# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- EKLF_TAD1 PF16832.5 EAU80160.2 - 0.39 10.6 7.9 0.93 9.4 0.2 3.7 3 0 0 3 3 3 0 Erythroid krueppel-like transcription factor, transactivation 1 Citrate_synt PF00285.21 EAU80161.1 - 7e-20 71.4 0.0 9e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EAU80161.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Methyltransf_4 PF02390.17 EAU80162.1 - 3.8e-51 173.0 0.0 4.9e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EAU80162.1 - 1.6e-05 25.5 0.0 0.0003 21.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU80162.1 - 0.0003 21.4 0.0 0.0074 16.9 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU80162.1 - 0.0099 16.6 0.0 0.045 14.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAU80162.1 - 0.022 14.3 0.0 0.28 10.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EAU80162.1 - 0.09 12.6 0.0 0.59 9.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain NAPRTase_N PF17767.1 EAU80163.2 - 4.9e-36 123.9 0.0 6.6e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 EAU80163.2 - 3.1e-12 46.6 0.0 4.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Cohesin PF00963.18 EAU80167.2 - 0.14 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Cohesin domain NAPRTase PF04095.16 EAU80168.2 - 4.6e-30 105.0 0.0 5.4e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Radial_spoke PF04712.12 EAU80171.1 - 0.081 11.9 0.9 0.082 11.8 0.9 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 EAU80171.1 - 3.5 5.6 6.9 4 5.4 6.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_7 PF00840.20 EAU80190.1 - 6.7e-206 684.1 7.3 7.6e-206 684.0 7.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 EAU80191.2 - 3.3e-89 299.6 5.6 4e-89 299.3 5.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF3043 PF11241.8 EAU80192.1 - 0.37 10.8 6.9 0.57 10.2 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PRC PF05239.16 EAU80198.1 - 0.0034 17.4 0.9 1.5 8.9 0.1 2.3 1 1 1 2 2 2 2 PRC-barrel domain DUF2171 PF09939.9 EAU80198.1 - 0.026 14.8 0.1 5.7 7.3 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) Baculo_DNA_bind PF04786.12 EAU80200.2 - 0.018 14.4 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 ssDNA binding protein Helicase_C PF00271.31 EAU80211.1 - 1.9e-08 34.6 0.0 4.7e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAU80211.1 - 4.7e-08 32.1 0.0 7e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 EAU80211.1 - 0.00012 21.4 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF4805 PF16063.5 EAU80211.1 - 0.075 12.4 0.4 0.59 9.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4805) Sigma70_r4 PF04545.16 EAU80211.1 - 0.093 12.3 0.3 0.29 10.7 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Pox_A_type_inc PF04508.12 EAU80214.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA_22 PF13401.6 EAU80217.1 - 0.19 12.0 0.0 0.66 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AXE1 PF05448.12 EAU80217.1 - 0.21 10.2 0.3 0.35 9.5 0.3 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) SRP-alpha_N PF04086.13 EAU80219.2 - 4.3 7.2 7.2 0.36 10.7 2.4 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Helicase_C PF00271.31 EAU80222.2 - 3e-10 40.4 0.1 8e-08 32.6 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU80222.2 - 1.5e-08 34.6 0.0 1.5e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EAU80222.2 - 0.0027 17.7 0.0 0.0088 16.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EAU80222.2 - 0.16 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.21 EAU80222.2 - 0.18 11.3 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SIN1 PF05422.12 EAU80228.2 - 5.1 7.6 13.5 0.22 12.1 1.6 2.8 2 1 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) DUF3987 PF13148.6 EAU80228.2 - 6.4 5.7 7.6 12 4.8 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Cwf_Cwc_15 PF04889.12 EAU80229.1 - 2.5 7.8 11.9 8 6.1 11.9 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPR_10 PF13374.6 EAU80230.2 - 8.7e-94 305.2 31.3 5.1e-08 32.5 0.0 13.8 12 1 1 13 13 13 13 Tetratricopeptide repeat TPR_12 PF13424.6 EAU80230.2 - 8e-35 119.0 27.1 0.031 14.6 0.0 14.1 14 1 0 14 14 14 11 Tetratricopeptide repeat CHAT PF12770.7 EAU80230.2 - 1.3e-25 90.5 0.0 2.1e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.6 EAU80230.2 - 1.6e-17 62.5 9.3 3.6 8.2 0.0 11.8 11 0 0 11 11 11 3 Tetratricopeptide repeat Yopt PF09467.10 EAU80230.2 - 1e-05 25.5 0.2 36 4.5 0.0 7.5 9 0 0 9 9 9 0 Hypothetical protein Yopt MAGI_u1 PF16663.5 EAU80230.2 - 0.00025 21.1 0.0 2.3e+02 1.9 0.0 7.5 11 0 0 11 11 11 0 Unstructured region on MAGI Glyco_hydro_65N PF03636.15 EAU80230.2 - 0.00088 19.0 0.1 13 5.4 0.0 5.8 5 2 1 8 8 8 1 Glycosyl hydrolase family 65, N-terminal domain TPR_14 PF13428.6 EAU80230.2 - 0.0053 17.5 30.9 2.4e+02 3.0 0.0 14.6 16 2 2 18 18 15 0 Tetratricopeptide repeat DUF4404 PF14357.6 EAU80230.2 - 0.0065 17.1 8.5 57 4.4 0.0 7.7 6 3 3 9 9 9 0 Domain of unknown function (DUF4404) Lantibiotic_a PF14867.6 EAU80230.2 - 0.17 11.6 2.2 60 3.5 0.0 4.8 6 0 0 6 6 5 0 Lantibiotic alpha TPR_1 PF00515.28 EAU80230.2 - 0.97 9.4 40.6 1.5e+02 2.4 0.0 16.0 21 0 0 21 21 21 0 Tetratricopeptide repeat UBA_4 PF14555.6 EAU80230.2 - 3.9 7.4 9.4 2.7e+02 1.5 0.1 6.2 6 0 0 6 6 6 0 UBA-like domain PIF1 PF05970.14 EAU80232.1 - 2.3e-25 89.6 0.1 7.7e-25 87.8 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU80232.1 - 4.9e-11 42.7 0.0 2e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU80232.1 - 2.9e-08 34.2 0.0 6.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU80232.1 - 0.21 11.3 0.5 1.2 8.8 0.5 2.2 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pkinase PF00069.25 EAU80233.2 - 2.1e-10 40.4 0.1 7e-10 38.7 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80233.2 - 2.5e-06 27.0 0.0 3.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU80233.2 - 0.038 13.3 0.0 0.092 12.0 0.0 1.5 1 1 1 2 2 2 0 Kinase-like Cas_Csa4 PF09703.10 EAU80233.2 - 0.096 12.0 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) zf-C2H2 PF00096.26 EAU80238.2 - 0.0043 17.4 2.2 0.0043 17.4 2.2 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 EAU80238.2 - 0.007 16.6 3.4 0.007 16.6 3.4 2.5 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EAU80238.2 - 0.11 12.5 3.1 0.33 11.0 1.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 EAU80238.2 - 0.12 12.1 4.9 0.41 10.4 0.9 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf_C2H2_ZHX PF18387.1 EAU80238.2 - 1.1 9.0 6.7 15 5.3 0.1 3.6 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 EAU80238.2 - 5.9 7.4 14.3 5.6 7.4 2.8 3.3 2 2 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 EAU80238.2 - 8.1 7.6 30.0 0.097 13.6 4.2 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 EAU80238.2 - 8.8 6.4 10.8 3 7.8 1.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain BUD22 PF09073.10 EAU80240.2 - 0.0022 17.4 29.7 0.0022 17.4 29.7 2.2 3 0 0 3 3 3 1 BUD22 GMC_oxred_N PF00732.19 EAU80241.2 - 1.6e-62 211.6 0.0 2e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU80241.2 - 7.6e-32 110.8 0.0 1.3e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU80241.2 - 0.00071 19.7 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU80241.2 - 0.0095 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAU80241.2 - 0.02 14.0 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EAU80241.2 - 0.02 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EAU80241.2 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Tet_JBP PF12851.7 EAU80242.2 - 0.065 12.6 0.0 1 8.6 0.0 2.0 1 1 1 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily DUF4510 PF14971.6 EAU80243.2 - 0.065 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Peptidase_C2 PF00648.21 EAU80258.2 - 6.9e-55 186.2 0.0 1.3e-53 181.9 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Peptidase_M43 PF05572.13 EAU80259.2 - 2.6e-16 59.9 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EAU80259.2 - 6e-05 23.6 0.0 0.0001 22.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EAU80259.2 - 0.00016 21.9 2.1 0.00028 21.1 2.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAU80259.2 - 0.0065 16.1 0.8 0.013 15.2 0.4 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU80259.2 - 0.015 15.2 0.1 0.036 13.9 0.1 1.5 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 EAU80259.2 - 0.22 10.7 0.1 0.34 10.1 0.1 1.2 1 0 0 1 1 1 0 Met-zincin PBP PF01161.20 EAU80267.2 - 2.2e-14 53.9 0.8 6e-14 52.5 0.8 1.7 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FYVE PF01363.21 EAU80269.1 - 4.5e-18 65.1 2.3 9.5e-18 64.1 2.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 EAU80269.1 - 0.28 11.4 5.8 1.3 9.3 3.3 2.7 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain CytochromB561_N PF09786.9 EAU80271.1 - 0.94 8.4 8.0 1.5 7.8 8.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Laminin_II PF06009.12 EAU80272.2 - 0.0017 18.4 4.2 0.0041 17.1 4.2 1.6 1 0 0 1 1 1 1 Laminin Domain II GAS PF13851.6 EAU80272.2 - 0.002 17.5 10.4 0.0033 16.8 10.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding EzrA PF06160.12 EAU80272.2 - 0.0025 16.1 5.3 0.0035 15.6 5.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Occludin_ELL PF07303.13 EAU80272.2 - 0.018 15.7 3.2 0.06 14.1 3.2 1.8 1 0 0 1 1 1 0 Occludin homology domain Sec8_exocyst PF04048.14 EAU80272.2 - 0.053 13.4 2.7 0.11 12.4 2.7 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TMPIT PF07851.13 EAU80272.2 - 0.065 12.5 6.5 0.12 11.6 6.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EAU80272.2 - 0.077 11.6 3.6 0.13 10.9 3.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PHTB1_C PF14728.6 EAU80272.2 - 0.11 11.6 2.2 0.17 11.0 2.2 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus TSNAXIP1_N PF15739.5 EAU80272.2 - 0.12 12.7 5.9 0.27 11.6 5.9 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus FUSC PF04632.12 EAU80272.2 - 0.13 10.7 0.5 0.18 10.3 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HsbA PF12296.8 EAU80272.2 - 0.14 12.6 0.3 0.32 11.4 0.3 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A BLOC1_2 PF10046.9 EAU80272.2 - 0.17 12.2 4.3 0.38 11.1 4.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.12 EAU80272.2 - 0.21 11.2 8.4 0.42 10.2 8.4 1.4 1 0 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.11 EAU80272.2 - 0.24 10.2 8.1 0.4 9.5 8.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 EAU80272.2 - 0.28 11.9 5.8 3.4 8.4 5.5 2.4 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EAU80272.2 - 0.41 11.1 11.3 2.3 8.7 0.2 2.4 1 1 1 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 EAU80272.2 - 0.44 9.8 6.3 0.91 8.8 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 EAU80272.2 - 0.5 9.3 16.3 0.015 14.3 7.4 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF5595 PF18077.1 EAU80272.2 - 0.62 10.2 4.9 0.55 10.3 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DivIVA PF05103.13 EAU80272.2 - 0.85 9.7 6.1 1.7 8.8 4.7 2.1 1 1 1 2 2 2 0 DivIVA protein Med9 PF07544.13 EAU80272.2 - 2.2 8.4 9.3 1.1 9.4 6.2 2.1 2 1 0 2 2 1 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.8 EAU80272.2 - 3.8 7.6 13.9 1.9 8.5 11.3 1.8 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding THOC7 PF05615.13 EAU80272.2 - 4.3 7.6 9.0 4.9 7.4 5.7 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 DivIC PF04977.15 EAU80272.2 - 5.4 6.8 10.2 5.2 6.9 2.0 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF349 PF03993.12 EAU80272.2 - 6 7.2 7.1 17 5.8 7.1 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) Seryl_tRNA_N PF02403.22 EAU80272.2 - 6.4 7.1 10.1 1.4 9.1 3.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF812 PF05667.11 EAU80272.2 - 7.9 5.2 13.6 13 4.6 13.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CENP-H PF05837.12 EAU80272.2 - 8 6.9 9.2 31 5.0 9.2 2.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) gag-asp_proteas PF13975.6 EAU80276.1 - 9.4e-05 22.9 0.8 0.00089 19.8 0.0 2.6 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EAU80276.1 - 0.00016 22.2 1.1 0.00048 20.7 0.0 2.4 3 0 0 3 3 3 1 Aspartyl protease zf-CCHC PF00098.23 EAU80276.1 - 0.0041 17.1 0.9 0.0079 16.2 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EAU80276.1 - 0.064 13.1 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Actin_micro PF17003.5 EAU80279.2 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Putative actin-like family zf-Di19 PF05605.12 EAU80279.2 - 0.03 14.6 0.3 0.042 14.1 0.3 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Pkinase_fungal PF17667.1 EAU80281.1 - 1.5e-51 175.5 0.0 2.1e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU80281.1 - 1.8e-07 30.8 0.0 5.8e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80281.1 - 0.025 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU80282.2 - 1.1e-45 156.2 0.0 1.2e-42 146.2 0.0 2.8 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU80282.2 - 3.3e-07 29.9 0.0 5.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80282.2 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Cauli_AT PF03233.13 EAU80283.2 - 0.014 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein SYF2 PF08231.12 EAU80283.2 - 0.041 14.3 0.0 0.074 13.5 0.0 1.4 1 1 0 1 1 1 0 SYF2 splicing factor SLR1-BP PF07333.12 EAU80285.2 - 0.51 10.8 7.6 0.8 10.2 7.6 1.2 1 0 0 1 1 1 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) TFIIA PF03153.13 EAU80286.2 - 0.63 10.0 19.8 0.94 9.4 19.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HeLo PF14479.6 EAU80287.2 - 0.005 16.7 3.8 0.005 16.7 3.8 2.4 2 0 0 2 2 2 1 Prion-inhibition and propagation NPV_P10 PF05531.12 EAU80287.2 - 0.013 16.0 1.5 0.03 14.8 0.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Noelin-1 PF12308.8 EAU80287.2 - 0.024 14.6 1.0 0.11 12.5 1.0 2.1 1 0 0 1 1 1 0 Neurogenesis glycoprotein BLOC1_2 PF10046.9 EAU80287.2 - 0.78 10.1 11.9 8 6.8 0.2 4.0 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lipoprotein_7 PF01540.16 EAU80287.2 - 2.1 7.5 9.5 4.9 6.4 9.5 1.5 1 1 0 1 1 1 0 Adhesin lipoprotein Laminin_II PF06009.12 EAU80287.2 - 3 7.9 15.7 0.18 11.8 2.9 3.1 3 1 0 3 3 3 0 Laminin Domain II AAA_13 PF13166.6 EAU80287.2 - 3 6.4 10.1 4.4 5.8 10.1 1.3 1 0 0 1 1 1 0 AAA domain Prefoldin PF02996.17 EAU80287.2 - 3.1 7.8 8.7 4.3 7.3 0.3 3.9 2 1 0 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 EAU80287.2 - 3.6 7.6 14.1 0.36 10.9 0.9 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EAU80287.2 - 5.9 4.7 5.6 2.3 6.1 2.0 1.8 2 0 0 2 2 2 0 Prominin Sec34 PF04136.15 EAU80287.2 - 8 6.3 7.8 27 4.6 3.1 2.5 2 0 0 2 2 2 0 Sec34-like family F-box PF00646.33 EAU80288.2 - 0.022 14.6 0.2 0.048 13.6 0.2 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EAU80288.2 - 0.038 13.9 0.2 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 F-box-like Nup84_Nup100 PF04121.13 EAU80288.2 - 0.097 10.8 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 ICMT PF04140.14 EAU80289.1 - 5.8e-13 49.1 1.3 5.5e-12 45.9 0.3 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAU80289.1 - 1.1e-08 35.5 3.4 2.3e-07 31.2 3.4 2.3 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EAU80289.1 - 0.018 13.8 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family DUF3955 PF13127.6 EAU80289.1 - 1.6 8.6 5.2 0.89 9.4 2.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3955) PTR2 PF00854.21 EAU80290.1 - 3.4e-72 243.5 4.7 5e-72 242.9 4.7 1.2 1 0 0 1 1 1 1 POT family CcmH PF03918.14 EAU80290.1 - 0.3 10.4 3.1 0.74 9.1 0.0 2.9 2 1 1 3 3 3 0 Cytochrome C biogenesis protein zf-MYND PF01753.18 EAU80291.2 - 2.6e-09 37.0 9.3 4.4e-09 36.3 9.3 1.4 1 0 0 1 1 1 1 MYND finger HATPase_c PF02518.26 EAU80294.2 - 2.5e-30 105.3 0.6 8.5e-30 103.5 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAU80294.2 - 1.7e-23 82.9 0.1 4.7e-23 81.5 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HAMP PF00672.25 EAU80294.2 - 5.9e-19 68.2 6.7 5e-07 30.0 0.1 4.7 4 0 0 4 4 4 3 HAMP domain HisKA PF00512.25 EAU80294.2 - 1.8e-17 63.1 1.1 6.9e-17 61.2 1.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain F-box-like PF12937.7 EAU80295.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like DsbD PF02683.15 EAU80296.1 - 0.059 13.3 1.5 0.23 11.3 1.0 1.8 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Peptidase_M43 PF05572.13 EAU80298.2 - 2.4e-09 37.3 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU80298.2 - 2.2e-06 27.9 0.2 3.9e-06 27.1 0.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU80298.2 - 0.00039 20.9 0.0 0.00069 20.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU80298.2 - 0.0082 16.0 0.3 0.01 15.7 0.3 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 EAU80298.2 - 0.017 14.8 0.4 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EAU80298.2 - 0.04 13.1 0.2 0.07 12.3 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_2 PF13574.6 EAU80298.2 - 0.079 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like GntP_permease PF02447.16 EAU80301.2 - 0.023 13.4 0.1 0.023 13.4 0.1 1.0 1 0 0 1 1 1 0 GntP family permease F-box-like PF12937.7 EAU80302.2 - 1.2e-07 31.5 1.5 1.2e-07 31.5 1.5 2.3 2 0 0 2 2 2 1 F-box-like Glyco_hydro_61 PF03443.14 EAU80304.1 - 5.2e-50 170.2 0.0 6.2e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MA-Mit PF09245.10 EAU80305.2 - 0.074 12.5 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen zf-C2HE PF16278.5 EAU80306.2 - 0.18 12.3 0.0 0.42 11.1 0.0 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Ferritin_2 PF13668.6 EAU80307.1 - 1.5e-35 122.4 0.0 2e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 EAU80308.1 - 4.7e-35 120.7 0.1 7.2e-35 120.1 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain DUF4231 PF14015.6 EAU80310.2 - 0.11 13.0 3.5 0.34 11.4 0.3 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) SHR3_chaperone PF08229.11 EAU80310.2 - 0.63 9.0 2.9 0.65 9.0 0.6 2.1 2 1 0 2 2 2 0 ER membrane protein SH3 Nop14 PF04147.12 EAU80311.1 - 4.3 5.4 22.6 5.4 5.1 22.6 1.0 1 0 0 1 1 1 0 Nop14-like family G-alpha PF00503.20 EAU80314.1 - 7.2e-112 374.0 0.0 8.5e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU80314.1 - 2.3e-11 43.5 0.0 2.1e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.6 EAU80314.1 - 0.014 15.7 0.2 0.14 12.4 0.0 2.8 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EAU80314.1 - 0.029 14.9 0.0 0.13 12.7 0.0 2.2 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EAU80314.1 - 0.03 13.5 0.1 0.054 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 EAU80314.1 - 0.039 13.7 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 EAU80314.1 - 0.042 14.1 0.0 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EAU80314.1 - 0.061 12.9 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EAU80314.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 EAU80314.1 - 0.077 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EAU80314.1 - 0.17 12.3 2.7 0.63 10.4 2.7 2.1 1 1 0 1 1 1 0 AAA ATPase domain MscS_porin PF12795.7 EAU80346.2 - 0.0067 16.0 0.6 0.017 14.7 0.6 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Tropomyosin_1 PF12718.7 EAU80346.2 - 0.095 12.9 0.4 0.2 11.8 0.4 1.5 1 0 0 1 1 1 0 Tropomyosin like SCAB_CC PF16712.5 EAU80346.2 - 0.098 12.5 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein SnAPC_2_like PF11035.8 EAU80347.2 - 0.025 14.7 1.0 0.025 14.7 1.0 1.4 2 0 0 2 2 2 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb Syntaxin-6_N PF09177.11 EAU80348.1 - 0.00071 20.1 0.3 0.001 19.6 0.3 1.2 1 0 0 1 1 1 1 Syntaxin 6, N-terminal DUF4795 PF16043.5 EAU80348.1 - 0.016 14.8 0.5 0.022 14.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) FlgN PF05130.12 EAU80348.1 - 0.058 13.9 0.2 0.079 13.5 0.2 1.2 1 0 0 1 1 1 0 FlgN protein JIP_LZII PF16471.5 EAU80348.1 - 0.069 13.3 0.4 0.21 11.8 0.1 1.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II NitrOD2 PF18550.1 EAU80348.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Nitrososphaera output domain 2 NUC130_3NT PF08158.12 EAU80348.1 - 0.17 12.3 0.2 4.8 7.6 0.1 2.1 2 0 0 2 2 2 0 NUC130/3NT domain zf-RVT PF13966.6 EAU80349.2 - 3.5e-06 27.7 1.3 1.3e-05 25.8 1.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF240 PF03086.14 EAU80349.2 - 0.15 12.0 0.2 0.77 9.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF240) KDZ PF18758.1 EAU80350.2 - 6.6e-58 196.0 0.0 1.1e-57 195.2 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Baculo_PEP_C PF04513.12 EAU80350.2 - 1.1 9.4 5.6 0.25 11.4 0.9 2.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus UPF0242 PF06785.11 EAU80350.2 - 4.1 7.5 6.0 0.33 11.0 0.1 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CCD PF07860.11 EAU80351.2 - 0.059 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 WisP family C-Terminal Region Reprolysin_2 PF13574.6 EAU80352.2 - 0.04 13.8 2.3 0.093 12.6 2.3 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3528 PF12045.8 EAU80353.2 - 0.0015 19.2 5.0 2.1 8.9 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3528) Anillin_N PF16018.5 EAU80353.2 - 0.0093 16.6 0.7 29 5.3 0.0 3.8 3 1 1 4 4 4 1 Anillin N-terminus DUF5308 PF17233.2 EAU80353.2 - 0.45 10.7 9.6 5.8 7.1 0.3 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5308) DUF1658 PF07871.11 EAU80353.2 - 3 7.9 15.7 32 4.7 0.3 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1658) SNF2_N PF00176.23 EAU80360.1 - 9.4e-22 77.2 0.0 1.5e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU80360.1 - 2.4e-14 53.6 0.0 5.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EAU80360.1 - 1.9e-07 30.6 0.1 3.8e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EAU80360.1 - 0.0004 20.4 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma70_r4 PF04545.16 EAU80360.1 - 0.9 9.1 3.0 0.35 10.4 0.1 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Cwf_Cwc_15 PF04889.12 EAU80361.1 - 0.073 12.8 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DPBB_1 PF03330.18 EAU80365.1 - 0.19 12.0 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 Lytic transglycolase TTSSLRR PF12468.8 EAU80366.2 - 0.061 13.6 0.8 0.35 11.1 0.8 2.3 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein GREB1 PF15782.5 EAU80366.2 - 7.7 3.5 9.5 12 2.8 9.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5082 PF16888.5 EAU80370.2 - 0.1 12.9 0.3 18 5.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Perilipin PF03036.16 EAU80371.2 - 0.00049 19.2 0.1 0.00062 18.9 0.1 1.0 1 0 0 1 1 1 1 Perilipin family Myc_target_1 PF15179.6 EAU80371.2 - 0.035 14.0 0.6 0.078 12.9 0.2 1.7 1 1 1 2 2 2 0 Myc target protein 1 LPD11 PF18824.1 EAU80371.2 - 0.11 12.5 0.0 6.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 End3 PF12761.7 EAU80374.1 - 0.066 13.4 3.1 0.085 13.0 0.9 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Zn_clus PF00172.18 EAU80376.2 - 1.9 8.7 8.0 1.7 8.9 0.7 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.7 EAU80378.2 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Zn-ribbon_8 PF09723.10 EAU80383.2 - 0.21 11.7 2.6 1.8 8.7 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain YhfH PF14149.6 EAU80383.2 - 3.6 7.6 5.8 7.4 6.6 5.8 1.5 1 0 0 1 1 1 0 YhfH-like protein zf-CCHC_2 PF13696.6 EAU80383.2 - 6.8 6.6 10.2 15 5.5 2.0 2.7 2 0 0 2 2 2 0 Zinc knuckle TACC_C PF05010.14 EAU80386.2 - 0.0029 17.4 4.0 0.0057 16.5 4.0 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 EAU80386.2 - 0.033 12.9 2.7 0.051 12.2 2.7 1.2 1 0 0 1 1 1 0 AAA domain DUF2721 PF11026.8 EAU80386.2 - 0.05 13.5 0.4 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Spc7 PF08317.11 EAU80386.2 - 0.06 12.2 5.3 0.11 11.4 5.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 EAU80386.2 - 0.15 12.3 2.7 0.46 10.8 2.7 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein Fib_alpha PF08702.10 EAU80386.2 - 0.16 12.2 3.1 0.41 10.8 3.1 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IFT57 PF10498.9 EAU80386.2 - 0.18 10.7 4.9 0.45 9.4 4.9 1.6 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMPIT PF07851.13 EAU80386.2 - 0.21 10.8 3.0 0.37 10.0 3.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF812 PF05667.11 EAU80386.2 - 0.55 9.0 11.9 0.026 13.4 5.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ZapB PF06005.12 EAU80386.2 - 1.1 9.8 9.6 1 9.9 7.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Cortex-I_coil PF09304.10 EAU80386.2 - 1.1 9.5 9.7 2.4 8.4 0.4 2.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil YqeY PF09424.10 EAU80386.2 - 2 8.5 6.9 0.71 9.9 4.0 1.7 2 0 0 2 2 2 0 Yqey-like protein UPF0242 PF06785.11 EAU80386.2 - 6.9 6.7 9.2 1.5 8.9 5.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LRR_8 PF13855.6 EAU80388.2 - 0.073 12.9 0.4 1.5 8.6 0.2 2.6 2 0 0 2 2 2 0 Leucine rich repeat DUF3944 PF13099.6 EAU80388.2 - 0.19 11.6 1.1 6.6 6.7 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) Helitron_like_N PF14214.6 EAU80393.2 - 3.4e-33 115.5 0.0 7.1e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Ran-binding PF05508.11 EAU80397.1 - 0.0011 18.1 0.8 0.0013 17.7 0.8 1.0 1 0 0 1 1 1 1 RanGTP-binding protein PLU-1 PF08429.11 EAU80397.1 - 0.027 13.6 0.2 0.03 13.5 0.2 1.2 1 0 0 1 1 1 0 PLU-1-like protein HBM PF16591.5 EAU80397.1 - 0.059 12.8 0.2 0.062 12.7 0.2 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF1664 PF07889.12 EAU80397.1 - 0.12 12.4 0.3 0.23 11.5 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) zf-CCHC PF00098.23 EAU80402.2 - 0.007 16.4 1.4 0.014 15.4 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EAU80402.2 - 0.0079 15.9 2.0 0.015 15.0 2.0 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EAU80402.2 - 0.022 14.6 1.7 0.044 13.6 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EAU80402.2 - 0.21 11.6 1.3 0.44 10.6 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Retrotran_gag_2 PF14223.6 EAU80413.2 - 3e-10 39.9 0.0 4.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EAU80413.2 - 0.00014 21.5 0.2 0.00024 20.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) PIH1_CS PF18201.1 EAU80413.2 - 0.058 13.8 0.7 0.16 12.4 0.7 1.7 1 0 0 1 1 1 0 PIH1 CS-like domain Presenilin PF01080.17 EAU80413.2 - 0.74 8.5 4.0 1.1 7.9 4.0 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EAU80413.2 - 1.3 8.2 2.6 1.9 7.7 2.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zf-BED PF02892.15 EAU80422.2 - 0.0002 21.3 0.9 0.00038 20.4 0.9 1.5 1 0 0 1 1 1 1 BED zinc finger HTH_Tnp_Tc5 PF03221.16 EAU80422.2 - 0.039 14.0 0.0 0.33 11.0 0.0 2.4 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain Retrotran_gag_2 PF14223.6 EAU80427.2 - 7.3e-09 35.4 0.4 1.1e-08 34.8 0.4 1.3 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF659 PF04937.15 EAU80430.2 - 0.011 15.6 0.2 0.025 14.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) RT_RNaseH_2 PF17919.1 EAU80432.2 - 4.2e-05 23.5 0.0 5.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EAU80432.2 - 8.1e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NAM PF02365.15 EAU80436.2 - 8.4 7.3 8.6 9.4 7.2 0.3 3.1 1 1 1 2 2 2 0 No apical meristem (NAM) protein DUF1688 PF07958.11 EAU80439.1 - 1.8e-173 577.1 0.0 2e-173 577.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.6 EAU80440.1 - 1.1e-09 37.4 31.2 5e-07 28.6 31.2 3.1 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 EAU80440.1 - 0.00079 18.4 3.4 0.0014 17.6 3.4 1.5 1 1 0 1 1 1 1 MFS_1 like family BT1 PF03092.16 EAU80440.1 - 0.0012 17.1 1.1 0.0027 16.0 1.1 1.5 1 0 0 1 1 1 1 BT1 family HPP PF04982.13 EAU80440.1 - 2.1 8.5 13.8 0.19 11.9 1.7 3.0 3 0 0 3 3 3 0 HPP family tRNA-synt_2b PF00587.25 EAU80442.2 - 3.3e-37 128.2 0.0 7.6e-37 127.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EAU80442.2 - 1.3e-17 63.7 0.2 1.5e-16 60.3 0.1 2.4 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 EAU80442.2 - 3e-14 52.8 0.0 2.4e-13 49.9 0.0 2.3 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 EAU80442.2 - 8.5e-13 48.2 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Big_4 PF07532.11 EAU80442.2 - 0.16 11.8 0.2 2.1 8.2 0.5 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) AAA_18 PF13238.6 EAU80443.2 - 0.00021 21.8 0.5 0.0014 19.2 0.5 2.1 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 EAU80443.2 - 0.0088 15.9 0.1 0.029 14.2 0.1 1.9 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 EAU80443.2 - 0.014 15.1 0.5 0.21 11.3 0.5 2.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EAU80443.2 - 0.04 14.1 0.1 0.26 11.4 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAU80443.2 - 0.04 14.2 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EAU80443.2 - 0.044 13.6 0.0 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase T2SSE PF00437.20 EAU80443.2 - 0.12 11.4 0.1 0.24 10.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EAU80443.2 - 0.2 11.4 0.0 0.33 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAU80443.2 - 0.2 12.1 0.0 0.25 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Spo7 PF03907.13 EAU80444.2 - 4.2e-43 147.4 0.1 6.3e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 EAU80444.2 - 0.0047 17.3 0.3 0.0047 17.3 0.3 1.7 2 1 0 2 2 2 1 Transmembrane protein 188 Adeno_E3B PF03376.14 EAU80445.2 - 0.085 13.1 4.2 0.1 12.8 0.5 2.3 2 0 0 2 2 2 0 Adenovirus E3B protein DUF4034 PF13226.6 EAU80445.2 - 0.12 11.7 1.7 0.35 10.2 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4034) Asp PF00026.23 EAU80448.2 - 2.5e-21 76.4 0.0 3.3e-19 69.5 0.0 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease CAS_CSE1 PF03378.15 EAU80449.1 - 5.8e-116 387.6 0.0 1e-115 386.8 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EAU80449.1 - 4.5e-105 351.5 0.0 8.1e-105 350.7 0.0 1.4 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.19 EAU80449.1 - 2.5e-13 49.7 0.1 1e-12 47.7 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EAU80449.1 - 0.004 17.5 0.1 1.8 9.0 0.1 3.3 2 0 0 2 2 2 1 HEAT repeats RsbRD_N PF14361.6 EAU80449.1 - 0.013 16.2 0.7 14 6.5 0.0 3.5 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Xpo1 PF08389.12 EAU80449.1 - 0.015 15.4 0.1 0.071 13.2 0.1 2.3 1 0 0 1 1 1 0 Exportin 1-like protein ANAPC4_WD40 PF12894.7 EAU80450.1 - 8.2e-19 67.7 3.0 7.9e-07 29.3 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU80450.1 - 6.7e-15 55.2 18.5 7.8e-06 26.5 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 EAU80450.1 - 0.00014 21.8 0.0 0.0097 15.8 0.0 3.1 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAU80450.1 - 0.045 12.7 0.1 4.9 6.0 0.0 3.4 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EAU80451.1 - 0.13 12.6 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Sec10 PF07393.11 EAU80452.2 - 1e-130 437.4 0.0 1.2e-130 437.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EAU80452.2 - 0.0023 17.8 0.0 0.0055 16.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain YscO PF07321.12 EAU80453.1 - 0.0035 17.3 0.2 0.0035 17.3 0.2 2.0 2 0 0 2 2 2 1 Type III secretion protein YscO HisKA PF00512.25 EAU80453.1 - 0.078 13.0 3.8 0.91 9.6 0.3 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain HpaP PF09483.10 EAU80453.1 - 0.31 11.3 2.5 0.26 11.5 0.6 1.7 2 0 0 2 2 2 0 Type III secretion protein (HpaP) Med17 PF10156.9 EAU80453.1 - 1.7 7.3 4.7 0.45 9.2 1.0 1.7 2 0 0 2 2 2 0 Subunit 17 of Mediator complex Tet_JBP PF12851.7 EAU80456.2 - 9.9e-10 38.3 0.0 1.5e-07 31.1 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily AIP3 PF03915.13 EAU80457.1 - 0.17 10.9 3.9 0.11 11.5 2.1 1.5 2 0 0 2 2 2 0 Actin interacting protein 3 KDZ PF18758.1 EAU80458.2 - 2.7e-47 161.2 0.1 5.2e-47 160.3 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU80458.2 - 2e-24 85.8 0.1 5.2e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU80458.2 - 0.0013 18.9 0.1 0.0032 17.6 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases C_Hendra PF16821.5 EAU80458.2 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 C protein from hendra and measles viruses Zn_clus PF00172.18 EAU80460.2 - 0.06 13.5 4.6 0.41 10.8 0.2 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.12 EAU80462.2 - 0.25 11.8 4.2 3.3 8.3 0.8 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Cytochrom_C_2 PF01322.20 EAU80465.2 - 0.088 13.7 0.0 0.22 12.4 0.0 1.6 2 0 0 2 2 2 0 Cytochrome C' FSIP1 PF15554.6 EAU80465.2 - 0.12 11.4 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 FSIP1 family TACC_C PF05010.14 EAU80468.2 - 0.003 17.4 4.3 0.0057 16.5 4.3 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AAA_13 PF13166.6 EAU80468.2 - 0.027 13.1 2.7 0.041 12.5 2.7 1.2 1 0 0 1 1 1 0 AAA domain DUF2721 PF11026.8 EAU80468.2 - 0.04 13.8 0.4 0.087 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Spc7 PF08317.11 EAU80468.2 - 0.05 12.5 5.3 0.089 11.7 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 EAU80468.2 - 0.12 12.6 2.6 0.35 11.2 2.6 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein Fib_alpha PF08702.10 EAU80468.2 - 0.14 12.4 3.1 0.34 11.1 3.1 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 EAU80468.2 - 0.18 11.0 3.0 0.31 10.3 3.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EAU80468.2 - 0.21 10.2 1.9 0.33 9.5 1.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF812 PF05667.11 EAU80468.2 - 0.44 9.4 11.9 0.021 13.8 5.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Cortex-I_coil PF09304.10 EAU80468.2 - 0.7 10.1 9.6 2.3 8.5 0.4 2.7 1 1 1 2 2 2 0 Cortexillin I, coiled coil ZapB PF06005.12 EAU80468.2 - 1.3 9.5 10.2 0.83 10.1 7.0 2.2 2 0 0 2 2 2 0 Cell division protein ZapB YqeY PF09424.10 EAU80468.2 - 1.6 8.8 6.9 0.59 10.2 4.0 1.7 2 0 0 2 2 2 0 Yqey-like protein HemX PF04375.14 EAU80468.2 - 3.1 7.0 9.4 0.62 9.3 5.4 1.8 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase IFT57 PF10498.9 EAU80468.2 - 3.7 6.4 9.5 0.37 9.7 4.9 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 GREB1 PF15782.5 EAU80469.1 - 1.8 5.6 9.6 2.4 5.2 9.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Med13_C PF06333.12 EAU80481.1 - 0.049 12.9 3.3 0.061 12.6 3.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain FXMRP1_C_core PF12235.8 EAU80481.1 - 0.067 13.8 2.8 0.11 13.1 2.8 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal RNA_pol_Rpb1_R PF05001.13 EAU80481.1 - 0.068 13.6 7.9 0.068 13.6 7.9 4.4 4 1 0 4 4 4 0 RNA polymerase Rpb1 C-terminal repeat Med3 PF11593.8 EAU80481.1 - 0.069 12.3 12.3 0.034 13.3 10.7 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal ORC6 PF05460.13 EAU80481.1 - 0.11 11.7 7.2 0.15 11.3 7.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TMEM61 PF15105.6 EAU80481.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 TMEM61 protein family SOG2 PF10428.9 EAU80481.1 - 0.18 11.0 3.1 0.18 11.0 3.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EAU80481.1 - 2.1 6.9 4.7 2.1 6.9 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein Proteasome PF00227.26 EAU80485.1 - 7.3e-40 136.5 0.0 9e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit 4HBT PF03061.22 EAU80486.1 - 1.5e-08 34.9 0.0 1.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EAU80486.1 - 0.00014 22.4 0.0 0.00017 22.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EAU80486.1 - 0.00085 18.7 1.0 0.0014 17.9 1.0 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Ribosomal_60s PF00428.19 EAU80487.2 - 6.3e-27 94.0 10.9 2.3e-26 92.2 10.9 2.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3695 PF12494.8 EAU80487.2 - 0.016 15.1 0.5 0.69 9.8 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) DUF4734 PF15881.5 EAU80487.2 - 0.1 12.8 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) LRAT PF04970.13 EAU80489.2 - 0.0068 16.7 1.2 0.03 14.6 0.0 2.2 1 1 0 2 2 2 1 Lecithin retinol acyltransferase Peptidase_C97 PF05903.14 EAU80489.2 - 0.15 11.9 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain ETF_QO PF05187.13 EAU80495.2 - 1e-12 48.0 0.1 1.9e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 EAU80495.2 - 1.3e-07 31.7 0.0 5.7e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU80495.2 - 1.9e-06 27.7 0.0 9.4e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU80495.2 - 9.6e-06 25.0 0.3 2.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU80495.2 - 1.3e-05 24.6 0.1 0.0012 18.2 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EAU80495.2 - 5.1e-05 22.5 0.6 0.00011 21.4 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAU80495.2 - 9.9e-05 21.2 0.3 0.00016 20.6 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EAU80495.2 - 0.00018 20.9 0.4 0.00034 20.0 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAU80495.2 - 0.00022 20.6 0.2 0.00037 19.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EAU80495.2 - 0.00023 21.2 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EAU80495.2 - 0.0046 16.0 0.1 0.007 15.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EAU80495.2 - 0.0072 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EAU80495.2 - 0.037 12.9 0.2 0.064 12.1 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 EAU80495.2 - 0.13 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A CTP_transf_1 PF01148.20 EAU80496.2 - 0.017 14.9 2.3 0.032 14.0 2.3 1.6 1 1 0 1 1 1 0 Cytidylyltransferase family MNHE PF01899.16 EAU80496.2 - 1.4 8.7 4.7 0.33 10.7 1.1 1.9 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit Docking PF08990.11 EAU80496.2 - 1.8 8.3 3.6 3.2 7.5 3.6 1.4 1 0 0 1 1 1 0 Erythronolide synthase docking HhH-GPD PF00730.25 EAU80497.2 - 0.0013 19.2 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_S17e PF00833.18 EAU80498.1 - 1.3e-60 202.6 0.0 1.6e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 EAU80499.1 - 5.3e-25 87.8 0.1 7.1e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 5_nucleotid_C PF02872.18 EAU80500.2 - 5.2e-26 91.8 0.0 1.1e-25 90.7 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EAU80500.2 - 4.6e-08 33.8 0.1 1.2e-07 32.4 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Endonuc-HincII PF09226.11 EAU80500.2 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease HincII LRR_4 PF12799.7 EAU80502.1 - 1.9 9.0 4.1 28 5.3 0.2 3.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) 4HBT PF03061.22 EAU80503.2 - 9.3e-07 29.1 0.1 3.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Fer2 PF00111.27 EAU80504.2 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PsbQ PF05757.11 EAU80505.1 - 0.26 11.0 2.2 0.25 11.0 0.3 1.9 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Plavaka PF18759.1 EAU80506.2 - 1.7e-39 136.0 0.0 1.9e-39 135.8 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase PQ-loop PF04193.14 EAU80507.2 - 1.5e-11 43.9 6.9 5.6e-11 42.0 0.3 3.2 3 0 0 3 3 3 2 PQ loop repeat DUF3382 PF11862.8 EAU80507.2 - 0.021 15.1 9.3 0.025 14.9 0.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF4191 PF13829.6 EAU80507.2 - 0.42 9.9 4.7 0.074 12.4 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) UPF0093 PF03653.13 EAU80507.2 - 1.3 9.2 9.8 1.1 9.5 0.2 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) Tet_JBP PF12851.7 EAU80519.2 - 9.9e-10 38.3 0.0 1.5e-07 31.1 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily HisKA PF00512.25 EAU80521.1 - 0.075 13.1 3.8 0.91 9.6 0.3 2.3 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain HpaP PF09483.10 EAU80521.1 - 0.29 11.4 2.5 0.26 11.5 0.6 1.8 2 0 0 2 2 2 0 Type III secretion protein (HpaP) DUF2383 PF09537.10 EAU80521.1 - 0.3 11.4 3.3 0.53 10.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) YscO PF07321.12 EAU80521.1 - 0.42 10.6 12.7 2.2 8.2 12.7 1.9 1 1 0 1 1 1 0 Type III secretion protein YscO Med17 PF10156.9 EAU80521.1 - 0.93 8.1 3.9 0.34 9.6 0.6 1.7 2 0 0 2 2 2 0 Subunit 17 of Mediator complex NOA36 PF06524.12 EAU80522.2 - 9.9 5.4 11.8 15 4.8 11.8 1.1 1 0 0 1 1 1 0 NOA36 protein KDZ PF18758.1 EAU80524.2 - 1.1e-44 152.7 0.4 1.9e-44 151.9 0.4 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU80524.2 - 3.8e-22 78.5 0.3 9.9e-22 77.1 0.3 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU80524.2 - 7.9e-05 22.8 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU80524.2 - 0.16 11.8 0.1 0.49 10.3 0.1 1.8 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases Perilipin PF03036.16 EAU80527.2 - 0.00049 19.2 0.1 0.00062 18.9 0.1 1.0 1 0 0 1 1 1 1 Perilipin family Myc_target_1 PF15179.6 EAU80527.2 - 0.035 14.0 0.6 0.078 12.9 0.2 1.7 1 1 1 2 2 2 0 Myc target protein 1 LPD11 PF18824.1 EAU80527.2 - 0.11 12.5 0.0 6.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 DDE_2 PF02914.15 EAU80532.2 - 0.0061 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage Mu transposase FAM195 PF14799.6 EAU80533.2 - 0.051 13.9 0.3 0.074 13.4 0.3 1.2 1 0 0 1 1 1 0 FAM195 family PIF1 PF05970.14 EAU80534.2 - 3.9e-05 23.0 0.4 0.0015 17.8 0.1 2.7 3 0 0 3 3 3 1 PIF1-like helicase AAA_30 PF13604.6 EAU80534.2 - 0.00043 20.1 0.1 0.00099 18.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU80534.2 - 0.0031 17.8 0.0 0.02 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.11 EAU80535.1 - 0.00058 18.8 6.8 0.00067 18.6 6.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein zf-CpG_bind_C PF12269.8 EAU80535.1 - 0.0055 16.5 0.9 0.0071 16.1 0.9 1.2 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain DUF4201 PF13870.6 EAU80535.1 - 0.018 14.7 5.8 0.021 14.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 EAU80535.1 - 0.093 12.8 1.1 0.17 11.9 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SapB_1 PF05184.15 EAU80535.1 - 0.16 12.0 0.3 0.37 10.9 0.3 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 ADH_zinc_N PF00107.26 EAU80537.2 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ATP_bind_3 PF01171.20 EAU80538.1 - 2e-18 66.8 0.1 3.7e-18 65.9 0.0 1.4 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 EAU80538.1 - 1.2e-15 56.7 5.0 1.2e-15 56.7 5.0 3.3 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 EAU80538.1 - 0.023 13.5 0.0 0.036 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RecR PF02132.15 EAU80538.1 - 1.2 8.7 8.6 0.067 12.8 1.4 2.6 3 0 0 3 3 3 0 RecR protein Peptidase_S9_N PF02897.15 EAU80539.1 - 1.3e-86 291.0 6.5 1.7e-86 290.7 6.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EAU80539.1 - 2.9e-61 206.6 0.5 3.8e-60 203.0 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EAU80539.1 - 0.013 15.4 0.1 0.12 12.2 0.1 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold EAF PF09816.9 EAU80540.1 - 2.8e-23 82.2 1.0 4.4e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor FAM220 PF15487.6 EAU80540.1 - 2 8.0 11.5 11 5.5 6.4 2.4 2 0 0 2 2 2 0 FAM220 family Ferritin_2 PF13668.6 EAU80541.1 - 1.8e-34 118.8 1.4 2.8e-34 118.2 1.4 1.3 1 0 0 1 1 1 1 Ferritin-like domain KH_8 PF17903.1 EAU80543.2 - 2.3e-33 114.1 0.5 2.1e-32 111.1 0.0 2.4 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EAU80543.2 - 0.00043 20.1 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EAU80543.2 - 0.02 14.7 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 KH domain Amidase PF01425.21 EAU80543.2 - 0.65 8.9 2.8 1 8.3 2.8 1.2 1 0 0 1 1 1 0 Amidase SNF2_N PF00176.23 EAU80544.2 - 3.8e-40 137.7 12.1 1.8e-39 135.5 0.0 4.1 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU80544.2 - 2.6e-12 47.1 0.1 1.1e-11 45.0 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 EAU80544.2 - 2.9e-05 24.3 6.2 2.9e-05 24.3 6.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EAU80544.2 - 3.2e-05 23.7 5.8 3.2e-05 23.7 5.8 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU80544.2 - 9e-05 22.2 5.7 9e-05 22.2 5.7 2.3 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EAU80544.2 - 0.00012 21.8 2.6 0.00031 20.5 2.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EAU80544.2 - 0.00034 20.9 3.9 0.00079 19.7 3.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EAU80544.2 - 0.0039 17.0 4.1 0.0039 17.0 4.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU80544.2 - 0.0085 16.2 5.5 0.0085 16.2 5.5 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EAU80544.2 - 0.011 15.7 1.0 0.029 14.4 1.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DEAD PF00270.29 EAU80544.2 - 0.046 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 EAU80544.2 - 3.2 7.9 14.7 0.022 14.8 5.5 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Apelin PF15360.6 EAU80544.2 - 4.6 7.9 6.4 16 6.1 0.1 2.7 2 0 0 2 2 2 0 APJ endogenous ligand Acyl-CoA_dh_1 PF00441.24 EAU80545.1 - 6.5e-25 88.1 0.4 9.7e-25 87.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAU80545.1 - 1.4e-17 63.6 1.5 1.6e-17 63.5 0.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EAU80545.1 - 3.4e-16 59.1 0.1 1.3e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EAU80545.1 - 1.7e-14 54.5 0.1 5.1e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain TAF1_subA PF14929.6 EAU80546.2 - 0.13 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A RRM_3 PF08777.11 EAU80548.1 - 3.6e-05 23.8 0.0 0.00032 20.7 0.0 2.4 1 1 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 EAU80548.1 - 0.0028 17.4 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box PF00646.33 EAU80551.1 - 7.4e-06 25.7 0.6 2.5e-05 24.0 0.6 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU80551.1 - 3e-05 23.8 0.3 8.3e-05 22.4 0.3 1.8 1 0 0 1 1 1 1 F-box-like UPF0242 PF06785.11 EAU80551.1 - 0.48 10.5 2.3 3.1 7.8 1.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_hydro_61 PF03443.14 EAU80552.2 - 6.5e-47 160.1 0.0 7.9e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DnaJ_CXXCXGXG PF00684.19 EAU80553.2 - 0.00071 19.9 6.2 0.078 13.4 0.8 2.5 2 0 0 2 2 2 2 DnaJ central domain Cytochrom_c3_2 PF14537.6 EAU80553.2 - 0.16 12.5 0.7 10 6.6 0.2 2.4 2 0 0 2 2 2 0 Cytochrome c3 Anti-TRAP PF15777.5 EAU80553.2 - 2.3 8.3 7.8 0.13 12.3 0.7 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein SH3_1 PF00018.28 EAU80555.2 - 3.8e-15 55.2 0.1 6.1e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU80555.2 - 2.2e-13 49.8 0.1 3.7e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU80555.2 - 1.1e-11 44.2 0.0 1.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L2_C PF03947.18 EAU80558.1 - 1.1e-46 158.1 3.6 1.7e-46 157.5 3.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAU80558.1 - 1.7e-15 56.7 0.1 4.4e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Response_reg PF00072.24 EAU80559.1 - 3e-20 72.5 0.2 5.4e-15 55.5 0.2 2.5 2 0 0 2 2 2 2 Response regulator receiver domain DUF3546 PF12066.8 EAU80560.1 - 3e-15 56.4 0.9 1.1e-14 54.5 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EAU80560.1 - 5.4e-15 56.3 1.3 2e-14 54.4 0.2 2.6 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 EAU80560.1 - 0.00034 20.3 3.5 0.00046 19.9 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 EAU80560.1 - 0.02 15.2 2.5 0.49 10.8 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.22 EAU80560.1 - 0.025 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EAU80561.1 - 0.00021 21.1 0.0 0.026 14.3 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GD_N PF16030.5 EAU80561.1 - 0.075 13.3 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 Serine protease gd N-terminus LRR_6 PF13516.6 EAU80563.2 - 0.45 10.7 2.8 8.4 6.7 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat ERG2_Sigma1R PF04622.12 EAU80564.2 - 8e-101 335.7 0.5 1e-100 335.3 0.5 1.1 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3950 PF13132.6 EAU80564.2 - 0.18 11.6 0.8 0.34 10.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) UAA PF08449.11 EAU80565.2 - 3.1e-63 213.8 9.4 3.8e-29 101.8 0.4 4.0 3 1 1 4 4 4 4 UAA transporter family YpmT PF17431.2 EAU80565.2 - 0.2 11.7 0.2 0.2 11.7 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized YmpT-like Cyclin_N PF00134.23 EAU80566.2 - 2.7e-11 43.3 0.0 4.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EAU80566.2 - 2.2e-10 41.2 0.0 2.2e-10 41.2 0.0 2.4 2 1 0 2 2 2 1 Cyclin F-box-like PF12937.7 EAU80567.2 - 1.6e-06 27.9 0.0 3.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like RCC1 PF00415.18 EAU80568.1 - 4.1e-19 68.9 8.2 2.7e-07 31.1 0.2 7.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAU80568.1 - 4.2e-09 36.0 15.8 5.2e-06 26.1 0.1 5.8 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat NmrA PF05368.13 EAU80569.1 - 8.5e-27 94.2 0.0 9.9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAU80569.1 - 2.4e-07 30.8 0.0 4.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding MIF4G_like_2 PF09090.11 EAU80570.1 - 5.6e-75 252.3 0.0 8.3e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 EAU80570.1 - 1.4e-65 220.6 0.0 2.6e-65 219.8 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 EAU80570.1 - 0.017 14.7 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 0 MIF4G domain DUF4407 PF14362.6 EAU80570.1 - 0.036 13.4 0.2 0.055 12.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4633 PF15464.6 EAU80570.1 - 0.15 12.2 0.2 0.37 11.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) PPR PF01535.20 EAU80571.2 - 0.024 14.8 0.1 97 3.6 0.0 3.8 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.6 EAU80571.2 - 0.047 13.9 0.0 14 6.0 0.0 3.6 3 0 0 3 3 3 0 PPR repeat family IF3_N PF05198.16 EAU80572.1 - 0.0025 18.1 0.0 0.005 17.1 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 EAU80572.1 - 0.0031 17.5 0.3 0.0031 17.5 0.3 2.1 1 1 1 2 2 2 1 Translation initiation factor IF-3, C-terminal domain adh_short PF00106.25 EAU80573.1 - 2.2e-05 24.0 0.1 0.16 11.4 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU80573.1 - 0.017 14.7 0.0 0.3 10.6 0.0 2.1 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase EMG1 PF03587.14 EAU80576.2 - 5.5e-25 88.2 0.0 1.9e-13 50.5 0.0 2.0 2 0 0 2 2 2 2 EMG1/NEP1 methyltransferase CRAL_TRIO PF00650.20 EAU80577.1 - 3e-36 124.5 0.0 4.8e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAU80577.1 - 8.3e-09 35.5 0.6 8.3e-09 35.5 0.6 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EAU80577.1 - 0.0056 16.8 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Porphobil_deam PF01379.20 EAU80578.1 - 2.4e-73 246.0 0.0 3.4e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EAU80578.1 - 1.1e-20 73.8 0.8 2.1e-20 72.9 0.8 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain S36_mt PF10937.8 EAU80579.1 - 8.1e-10 40.3 4.0 1.3e-07 33.2 4.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial IMUP PF15761.5 EAU80579.1 - 0.011 16.4 1.4 0.013 16.1 1.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EAU80579.1 - 0.077 12.6 3.2 0.078 12.6 3.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUZ PF12752.7 EAU80579.1 - 0.093 13.5 0.2 0.15 12.8 0.2 1.4 1 0 0 1 1 1 0 SUZ domain RCDG1 PF15725.5 EAU80579.1 - 0.31 11.5 7.5 0.46 11.0 7.3 1.5 1 1 0 1 1 1 0 Renal cancer differentiation gene 1 protein AF-4 PF05110.13 EAU80579.1 - 1.4 6.9 7.9 1.8 6.6 7.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Proteasome PF00227.26 EAU80580.1 - 6.4e-44 149.7 0.0 2.3e-43 147.9 0.0 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAU80580.1 - 1.1e-14 53.7 0.3 2.1e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb1_1 PF04997.12 EAU80581.1 - 1.1e-85 287.7 0.0 1.9e-85 287.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EAU80581.1 - 1.1e-80 270.9 0.1 1.7e-80 270.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EAU80581.1 - 3.9e-74 248.4 0.0 7.4e-74 247.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EAU80581.1 - 8.6e-38 129.7 0.0 5.9e-36 123.8 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EAU80581.1 - 1.1e-32 112.1 0.0 2.6e-32 111.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 WW PF00397.26 EAU80582.1 - 0.034 14.2 0.8 0.062 13.4 0.8 1.4 1 0 0 1 1 1 0 WW domain HTH_1 PF00126.27 EAU80583.2 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family S4 PF01479.25 EAU80584.2 - 7.4e-11 41.6 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EAU80584.2 - 1.7e-10 41.6 0.2 2.5e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain LIM_bind PF01803.16 EAU80585.2 - 1e-66 224.9 0.3 6.4e-66 222.3 0.0 2.6 2 0 0 2 2 2 1 LIM-domain binding protein Kinesin PF00225.23 EAU80586.2 - 8.3e-87 291.2 0.0 1.3e-86 290.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 EAU80586.2 - 3e-42 144.9 0.0 7.7e-42 143.6 0.0 1.8 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EAU80586.2 - 7.6e-27 94.6 7.5 1.2e-17 64.6 2.6 3.3 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 EAU80586.2 - 7.9e-11 42.1 0.0 1.7e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 EAU80586.2 - 5.2e-10 39.8 0.0 1.6e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 PH domain KIF1B PF12423.8 EAU80586.2 - 7.7e-06 26.2 2.3 2.9e-05 24.4 0.6 2.8 2 0 0 2 2 2 1 Kinesin protein 1B FHA PF00498.26 EAU80586.2 - 2.6e-05 24.5 0.0 0.00011 22.5 0.0 2.1 2 0 0 2 2 2 1 FHA domain CMAS PF02353.20 EAU80587.1 - 9.1e-55 185.9 0.0 1.2e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EAU80587.1 - 2.4e-08 34.5 0.0 5.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU80587.1 - 8e-06 26.4 0.0 1.8e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU80587.1 - 0.0021 17.9 0.0 0.0036 17.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain ELFV_dehydrog_N PF02812.18 EAU80587.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Methyltransf_31 PF13847.6 EAU80587.1 - 0.055 13.3 0.0 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.25 EAU80594.2 - 0.00059 19.7 0.0 0.13 12.1 0.0 2.6 1 1 1 2 2 2 2 Lipase (class 3) Peptidase_M24 PF00557.24 EAU80595.2 - 2.1e-54 184.4 0.1 2.9e-54 183.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EAU80595.2 - 7e-35 119.4 0.0 1.5e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Nop PF01798.18 EAU80596.1 - 4.9e-86 287.9 0.2 4.9e-86 287.9 0.2 2.2 2 1 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EAU80596.1 - 3.5e-21 75.3 0.1 3.5e-21 75.3 0.1 2.8 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF2052 PF09747.9 EAU80596.1 - 1.7 8.7 23.6 3.1 7.9 23.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) F-box-like PF12937.7 EAU80597.1 - 5.1e-07 29.5 0.6 2.2e-06 27.5 0.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU80597.1 - 0.0041 17.5 5.5 0.55 10.7 0.3 4.7 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) Med26 PF08711.11 EAU80599.2 - 4.3e-10 39.5 0.0 8.9e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF1572 PF07609.11 EAU80599.2 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) HMG_box PF00505.19 EAU80600.1 - 1e-19 70.7 3.5 2.3e-19 69.6 3.5 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU80600.1 - 2.6e-14 53.5 3.4 2.6e-14 53.5 3.4 2.0 2 0 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 EAU80600.1 - 4.4e-05 23.4 0.0 7.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF2924 PF11149.8 EAU80600.1 - 0.14 12.5 2.1 0.35 11.3 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Hid1 PF12722.7 EAU80600.1 - 0.48 8.5 20.9 0.59 8.2 20.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WW PF00397.26 EAU80601.1 - 1.7e-08 34.4 7.3 1.7e-08 34.4 7.3 1.7 2 0 0 2 2 2 1 WW domain F-box-like PF12937.7 EAU80602.2 - 1.5e-08 34.3 1.9 2.7e-07 30.4 0.0 2.8 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.6 EAU80602.2 - 0.15 11.8 7.6 0.24 11.2 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat FumaraseC_C PF10415.9 EAU80602.2 - 0.15 12.5 0.3 0.26 11.7 0.3 1.3 1 0 0 1 1 1 0 Fumarase C C-terminus F-box-like PF12937.7 EAU80603.1 - 0.00027 20.8 0.0 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 F-box-like PHINT_rpt PF14882.6 EAU80604.2 - 0.67 10.3 2.1 0.97 9.8 0.0 2.3 2 0 0 2 2 2 0 Phage-integrase repeat unit HlyC PF02794.16 EAU80608.2 - 0.031 14.2 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 RTX toxin acyltransferase family Hydrophobin PF01185.18 EAU80609.1 - 1e-27 96.6 13.2 1.3e-27 96.2 13.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin PhoLip_ATPase_C PF16212.5 EAU80611.2 - 5.6e-71 239.2 28.4 5.6e-71 239.2 28.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAU80611.2 - 1.2e-21 76.2 1.8 3e-21 74.9 1.8 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAU80611.2 - 1.8e-12 48.0 1.1 4e-06 27.3 0.0 3.7 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAU80611.2 - 3.6e-11 43.0 0.0 2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU80611.2 - 3.2e-05 23.8 1.4 0.0075 16.0 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAU80611.2 - 0.0017 17.9 0.0 0.0017 17.9 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase DUF4175 PF13779.6 EAU80614.2 - 0.025 12.5 6.4 0.037 11.9 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF812 PF05667.11 EAU80614.2 - 0.028 13.3 1.9 0.035 13.0 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) UPF0242 PF06785.11 EAU80614.2 - 0.26 11.4 2.1 0.36 10.9 2.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SOGA PF11365.8 EAU80614.2 - 0.35 12.0 4.6 11 7.3 0.2 2.3 2 0 0 2 2 2 0 Protein SOGA YlqD PF11068.8 EAU80614.2 - 1.7 9.0 9.5 2.7 8.4 9.5 1.2 1 0 0 1 1 1 0 YlqD protein HemX PF04375.14 EAU80614.2 - 4.8 6.4 8.9 8.8 5.5 8.9 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 EAU80614.2 - 6 7.2 7.7 11 6.3 7.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ANAPC4_WD40 PF12894.7 EAU80615.2 - 0.0022 18.3 0.0 0.15 12.4 0.0 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU80615.2 - 0.014 16.2 4.2 9.8 7.2 0.5 4.4 3 1 1 4 4 4 0 WD domain, G-beta repeat PRKG1_interact PF15898.5 EAU80615.2 - 0.057 14.3 0.7 0.17 12.8 0.7 1.8 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain NRBF2 PF08961.10 EAU80615.2 - 2.9 7.5 8.6 0.26 10.9 2.6 2.1 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator UCH PF00443.29 EAU80616.2 - 1e-35 123.5 0.0 1.5e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EAU80616.2 - 5.9e-32 110.9 0.0 9.6e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 EAU80616.2 - 1.3e-06 28.2 0.0 0.00012 21.8 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF382 PF04037.13 EAU80617.2 - 2.1e-60 202.4 0.5 2.1e-60 202.4 0.5 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EAU80617.2 - 1.3e-17 63.4 4.7 2.6e-17 62.4 4.7 1.5 1 0 0 1 1 1 1 PSP hNIFK_binding PF12196.8 EAU80617.2 - 0.044 13.3 0.2 0.15 11.5 0.2 2.0 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK BSP_II PF05432.11 EAU80617.2 - 2.6 7.7 20.1 5.6 6.6 4.2 2.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) MitMem_reg PF13012.6 EAU80618.2 - 2e-34 118.4 1.0 3.3e-34 117.7 1.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EAU80618.2 - 1.1e-30 106.1 0.0 2.3e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Connexin PF00029.19 EAU80618.2 - 0.037 13.8 0.7 0.059 13.1 0.7 1.3 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 EAU80618.2 - 0.14 12.2 1.5 0.24 11.5 1.5 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Hydrophobin PF01185.18 EAU80619.1 - 1.5e-27 96.1 13.5 1.8e-27 95.7 13.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EAU80621.1 - 1.6e-27 96.0 13.2 2e-27 95.6 13.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EAU80622.1 - 1.4e-23 83.3 11.4 1.7e-23 83.0 11.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.7 EAU80623.2 - 5.7e-05 22.9 0.6 0.00019 21.3 0.6 2.0 1 1 0 1 1 1 1 F-box-like DUF4921 PF16268.5 EAU80623.2 - 0.056 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) Coa1 PF08695.10 EAU80624.1 - 5.5e-29 100.3 0.0 6.9e-28 96.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Glyco_hydro_16 PF00722.21 EAU80625.1 - 2.3e-19 69.6 0.1 2.3e-19 69.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 EAU80626.1 - 3.3e-57 193.6 0.2 3.3e-57 193.6 0.2 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAU80626.1 - 3.1e-07 30.5 0.0 1.6e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EAU80626.1 - 0.0021 17.9 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 ADH_zinc_N PF00107.26 EAU80627.1 - 6.1e-21 74.8 0.3 9.2e-21 74.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU80627.1 - 1.3e-08 35.9 0.4 2.2e-08 35.2 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU80627.1 - 4.2e-07 29.8 0.2 5.2e-06 26.3 0.0 2.6 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EAU80627.1 - 0.0058 16.1 0.5 0.0076 15.8 0.5 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ACP_syn_III_C PF08541.10 EAU80627.1 - 0.014 15.5 1.0 0.39 10.9 0.6 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.21 EAU80627.1 - 0.065 12.5 3.1 0.13 11.6 3.1 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-C2H2 PF00096.26 EAU80632.2 - 0.0011 19.3 13.3 0.45 11.1 0.0 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type Clathrin PF00637.20 EAU80634.2 - 3.1e-17 62.8 0.3 7.9e-13 48.5 0.1 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 EAU80634.2 - 8e-10 38.8 0.3 1.7e-09 37.7 0.3 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EAU80634.2 - 4.4e-07 29.8 8.9 7.8e-07 29.0 8.9 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EAU80634.2 - 0.00011 21.9 8.6 0.0002 21.2 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU80634.2 - 0.0056 16.6 8.3 0.0093 15.9 8.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAU80634.2 - 0.0092 16.3 8.9 0.018 15.4 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU80634.2 - 0.013 15.6 6.9 0.026 14.6 6.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger TPR_11 PF13414.6 EAU80634.2 - 0.017 14.8 0.1 0.21 11.3 0.2 2.3 2 0 0 2 2 2 0 TPR repeat RPN7 PF10602.9 EAU80634.2 - 0.026 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 FliG_N PF14842.6 EAU80634.2 - 0.1 13.1 0.3 0.41 11.2 0.1 2.1 2 0 0 2 2 2 0 FliG N-terminal domain zf-rbx1 PF12678.7 EAU80634.2 - 3.8 7.9 7.8 7.6 6.9 7.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAU80634.2 - 8.4 6.4 8.4 16 5.5 8.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cerato-platanin PF07249.12 EAU80636.2 - 1.1e-26 93.2 0.3 1.4e-26 93.0 0.3 1.1 1 0 0 1 1 1 1 Cerato-platanin GFA PF04828.14 EAU80637.2 - 1.7e-18 66.7 0.3 2.3e-18 66.3 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 EAU80637.2 - 0.031 14.8 1.0 1.9 9.1 0.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Hydrophobin PF01185.18 EAU80639.1 - 2.7e-27 95.2 14.2 3.3e-27 94.9 14.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin HSF_DNA-bind PF00447.17 EAU80641.1 - 1.1e-33 115.7 1.3 1.8e-33 115.0 1.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EAU80641.1 - 0.14 12.7 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 Ets-domain 4HBT_3 PF13622.6 EAU80644.1 - 1.9e-23 84.0 0.5 2.9e-23 83.4 0.4 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Glyco_hydro_11 PF00457.17 EAU80651.2 - 2.4e-51 173.9 2.1 2.8e-51 173.6 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 F-box-like PF12937.7 EAU80652.1 - 1.2e-10 41.1 0.0 3.6e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU80652.1 - 0.00026 20.8 0.3 0.0011 18.7 0.3 2.1 1 1 0 1 1 1 1 F-box domain Defensin_5 PF18251.1 EAU80653.2 - 4.7e-05 23.4 16.9 4.7e-05 23.4 16.9 1.9 2 0 0 2 2 2 1 Fungal defensin Copsin DUF4360 PF14273.6 EAU80661.2 - 2.8e-31 108.8 0.1 5.8e-31 107.7 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 EAU80662.2 - 1.8e-20 73.5 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase_fungal PF17667.1 EAU80664.2 - 1.4e-46 159.1 0.0 1.5e-23 83.3 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU80664.2 - 2.3e-10 40.3 0.0 3.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SWIM PF04434.17 EAU80667.2 - 0.0083 15.8 0.3 0.0083 15.8 0.3 1.7 2 0 0 2 2 2 1 SWIM zinc finger F-box-like PF12937.7 EAU80668.2 - 4.6e-15 55.2 0.1 1.2e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU80668.2 - 7.9e-07 28.8 0.0 2.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 EAU80668.2 - 0.052 13.1 3.3 0.35 10.5 1.6 2.4 2 0 0 2 2 2 0 F-box Glyco_hydro_6 PF01341.17 EAU80669.1 - 5.2e-96 322.0 1.2 6.4e-96 321.7 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.17 EAU80670.2 - 1.2e-94 317.5 0.1 1.5e-94 317.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Response_reg PF00072.24 EAU80672.1 - 8.9e-25 87.0 0.1 1.5e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain SUIM_assoc PF16619.5 EAU80672.1 - 1.7 8.8 16.7 1.3 9.2 0.4 4.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 HSF_DNA-bind PF00447.17 EAU80674.2 - 3.2e-32 111.0 1.8 5.5e-32 110.2 1.8 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Leu_zip PF15294.6 EAU80674.2 - 0.002 17.7 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Leucine zipper CCDC92 PF14916.6 EAU80674.2 - 0.018 14.8 0.2 0.047 13.5 0.2 1.7 1 0 0 1 1 1 0 Coiled-coil domain of unknown function UPF0242 PF06785.11 EAU80674.2 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 EAU80674.2 - 0.15 11.9 5.8 0.4 10.5 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 EAU80674.2 - 0.21 12.1 2.7 9.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 EAU80674.2 - 0.33 11.4 0.1 0.33 11.4 0.1 2.3 2 0 0 2 2 2 0 Cell division protein ZapB DUF4404 PF14357.6 EAU80674.2 - 2.3 8.9 5.0 7.1 7.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) CFEM PF05730.11 EAU80675.2 - 5.3e-07 29.6 7.0 9.7e-07 28.8 7.0 1.4 1 0 0 1 1 1 1 CFEM domain ABC_tran PF00005.27 EAU80676.2 - 1.8e-14 54.4 0.0 1.3e-13 51.7 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EAU80676.2 - 7.1e-05 22.5 0.1 0.00018 21.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EAU80676.2 - 9.1e-05 22.4 0.0 0.073 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EAU80676.2 - 0.0012 19.2 0.0 0.0035 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EAU80676.2 - 0.0082 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.17 EAU80676.2 - 0.0086 15.8 0.1 0.71 9.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 EAU80676.2 - 0.015 15.0 0.1 0.054 13.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAU80676.2 - 0.021 15.1 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAU80676.2 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EAU80676.2 - 0.16 12.3 0.1 0.48 10.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EAU80676.2 - 0.19 11.8 0.3 9.3 6.3 0.4 2.4 2 0 0 2 2 2 0 Dynamin family Cellulase PF00150.18 EAU80677.2 - 3.5e-09 36.5 0.0 5.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.32 EAU80678.2 - 2.3e-114 370.0 33.7 4.3e-09 36.8 0.0 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU80678.2 - 8.4e-50 167.0 0.8 0.00011 22.4 0.0 12.9 2 2 11 13 13 13 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU80678.2 - 1.5e-21 76.7 3.2 0.045 12.7 0.0 10.9 4 3 6 11 11 11 5 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 EAU80678.2 - 8.9e-09 35.5 0.0 1.6e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 EAU80678.2 - 3e-08 33.4 8.1 2.5 8.2 0.0 9.4 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EAU80678.2 - 4e-08 32.4 6.3 0.55 8.8 0.0 7.9 6 4 3 10 10 10 3 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 EAU80678.2 - 1.1e-05 25.0 7.4 1 9.1 0.0 7.4 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature AAA PF00004.29 EAU80678.2 - 9.4e-05 22.9 0.0 0.00029 21.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytochrom_D1 PF02239.16 EAU80678.2 - 9.9e-05 21.0 0.4 0.13 10.8 0.0 4.0 4 1 0 4 4 4 1 Cytochrome D1 heme domain AAA_22 PF13401.6 EAU80678.2 - 0.00014 22.2 0.1 0.00054 20.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Peptidase_S9_N PF02897.15 EAU80678.2 - 0.0002 20.3 0.1 4.5 5.9 0.0 4.9 4 2 1 5 5 5 2 Prolyl oligopeptidase, N-terminal beta-propeller domain WD40_like PF17005.5 EAU80678.2 - 0.00021 20.7 0.0 3.4 6.9 0.0 5.1 5 2 2 7 7 7 1 WD40-like domain AAA_16 PF13191.6 EAU80678.2 - 0.0049 17.3 0.0 0.02 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EAU80678.2 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EAU80678.2 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Nucleoporin_N PF08801.11 EAU80678.2 - 0.076 11.7 0.1 81 1.8 0.0 4.3 4 1 1 5 5 5 0 Nup133 N terminal like VID27 PF08553.10 EAU80678.2 - 0.09 11.8 0.0 2 7.4 0.0 2.9 4 0 0 4 4 4 0 VID27 C-terminal WD40-like domain PQQ_2 PF13360.6 EAU80678.2 - 0.094 12.3 2.7 9.5 5.7 0.3 3.8 2 2 1 3 3 3 0 PQQ-like domain AAA_19 PF13245.6 EAU80678.2 - 0.1 12.9 0.0 7.2 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ret2_MD PF18528.1 EAU80678.2 - 0.13 12.7 0.0 1.3e+02 3.0 0.0 4.5 5 0 0 5 5 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain PQQ_3 PF13570.6 EAU80678.2 - 1.1 9.9 13.9 11 6.6 0.0 6.3 6 1 1 7 7 6 0 PQQ-like domain Ras PF00071.22 EAU80679.1 - 1.7e-50 170.8 0.0 5.6e-50 169.1 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAU80679.1 - 8.3e-30 103.5 0.0 1.2e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU80679.1 - 2.1e-11 43.6 0.0 2.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAU80679.1 - 0.0001 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAU80679.1 - 0.0012 18.4 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DEAD PF00270.29 EAU80684.1 - 1.3e-44 152.1 2.3 1.3e-44 152.1 0.6 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU80684.1 - 6.8e-33 113.3 0.4 2.2e-31 108.5 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU80684.1 - 2.7e-06 27.5 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAU80684.1 - 0.00022 21.6 1.6 0.0043 17.4 0.4 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU80684.1 - 0.00048 19.9 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EAU80684.1 - 0.081 12.9 0.1 0.3 11.1 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 EAU80684.1 - 0.097 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase DSPc PF00782.20 EAU80685.2 - 4.5e-23 81.5 0.0 5.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EAU80685.2 - 0.00036 20.8 0.0 0.00057 20.2 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EAU80685.2 - 0.0034 17.0 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase MFS_1 PF07690.16 EAU80686.2 - 1.2e-24 86.9 76.0 1.5e-17 63.5 42.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sporozoite_P67 PF05642.11 EAU80686.2 - 0.11 10.6 1.4 0.14 10.2 1.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen E1-E2_ATPase PF00122.20 EAU80686.2 - 2.5 7.6 5.4 0.39 10.2 1.5 1.6 2 0 0 2 2 2 0 E1-E2 ATPase Chibby PF14645.6 EAU80690.2 - 0.049 14.0 0.3 0.049 14.0 0.3 3.6 3 1 0 4 4 4 0 Chibby family Spc7 PF08317.11 EAU80690.2 - 0.84 8.5 30.5 0.88 8.4 7.3 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein tRNA-synt_1d PF00750.19 EAU80690.2 - 1.5 7.6 6.9 0.25 10.3 1.3 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) DUF4407 PF14362.6 EAU80690.2 - 2 7.7 34.3 0.012 14.9 13.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) GAS PF13851.6 EAU80690.2 - 2.8 7.2 38.6 0.57 9.5 13.1 3.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding UPF0231 PF06062.11 EAU80690.2 - 4.7 7.5 6.1 30 4.9 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0231) DUF1003 PF06210.11 EAU80691.2 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) F-box-like PF12937.7 EAU80692.1 - 1.7e-10 40.6 0.6 5.6e-10 39.0 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU80692.1 - 0.00039 20.2 0.6 0.0016 18.3 0.6 2.1 1 1 0 1 1 1 1 F-box domain zf-CCHC PF00098.23 EAU80696.2 - 2.1e-54 179.3 62.7 1.3e-08 34.5 3.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EAU80696.2 - 6e-11 41.9 44.3 0.0038 16.9 1.1 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EAU80696.2 - 4e-10 39.5 42.1 0.042 13.8 0.2 7.0 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.6 EAU80696.2 - 0.0044 16.8 53.8 0.075 12.9 1.6 7.1 6 1 1 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 EAU80696.2 - 0.011 15.5 0.6 0.011 15.5 0.6 7.4 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_5 PF14787.6 EAU80696.2 - 0.027 14.2 45.9 0.066 12.9 2.8 6.7 6 1 1 7 7 7 0 GAG-polyprotein viral zinc-finger COX4 PF02936.14 EAU80697.1 - 1.5e-36 125.5 0.0 1.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 EAU80697.1 - 0.096 13.2 1.1 0.26 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Unstab_antitox PF09720.10 EAU80697.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.4 2 1 0 2 2 2 0 Putative addiction module component Solute_trans_a PF03619.16 EAU80699.2 - 7.4e-52 176.5 20.1 3.2e-29 102.3 9.1 3.0 1 1 1 2 2 2 2 Organic solute transporter Ostalpha Fibrillarin PF01269.17 EAU80700.1 - 7.5e-101 336.0 0.0 8.5e-101 335.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EAU80700.1 - 1.4e-05 24.9 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EAU80700.1 - 0.003 17.3 0.1 0.0054 16.5 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_MCEL PF03291.16 EAU80700.1 - 0.014 14.5 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_25 PF13649.6 EAU80700.1 - 0.017 15.8 0.0 0.026 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EAU80700.1 - 0.042 14.0 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EAU80700.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF2423 PF10338.9 EAU80700.1 - 0.14 12.4 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) PMT PF02366.18 EAU80701.2 - 1.1e-82 277.3 17.3 1.1e-82 277.3 17.3 1.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAU80701.2 - 1.6e-59 200.9 15.9 1.6e-59 200.9 15.9 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EAU80701.2 - 2.5e-26 92.7 0.7 3.9e-26 92.0 0.7 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EAU80701.2 - 0.002 18.4 12.6 0.002 18.4 12.6 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4969 PF16339.5 EAU80701.2 - 0.013 15.8 0.1 0.068 13.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) Abhydrolase_9_N PF15420.6 EAU80701.2 - 8.4 6.3 16.2 0.14 12.1 0.5 3.7 3 1 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus MFS_1 PF07690.16 EAU80704.2 - 1.2e-19 70.5 75.5 1e-16 60.8 43.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ING PF12998.7 EAU80706.1 - 6.8e-15 55.5 0.1 1e-14 54.9 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EAU80706.1 - 6.7e-05 22.7 9.3 0.00011 22.0 9.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EAU80706.1 - 0.014 15.6 0.3 0.031 14.5 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hydrophobin PF01185.18 EAU80707.1 - 1.6e-27 96.0 13.8 1.9e-27 95.7 13.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin FAD_binding_4 PF01565.23 EAU80708.1 - 4.7e-21 75.0 0.1 8.2e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU80708.1 - 4.8e-13 49.0 0.1 9.4e-13 48.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like RuBisCO_large PF00016.20 EAU80708.1 - 0.029 13.6 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Acetyltransf_1 PF00583.25 EAU80718.1 - 3.2e-14 53.2 0.0 4.8e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU80718.1 - 1.4e-12 47.7 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU80718.1 - 6.9e-11 42.4 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAU80718.1 - 0.00065 19.8 0.0 0.0024 18.0 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAU80718.1 - 0.002 18.2 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EAU80718.1 - 0.0022 18.2 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU80718.1 - 0.0026 17.7 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EAU80718.1 - 0.0034 18.1 0.0 0.0087 16.7 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Piwi PF02171.17 EAU80720.2 - 3.9e-80 269.3 0.0 5.6e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EAU80720.2 - 9.5e-25 87.8 0.0 2.7e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoMid PF16487.5 EAU80720.2 - 1.3e-15 57.4 0.0 2.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 EAU80720.2 - 4.5e-15 55.1 0.0 9.6e-15 54.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EAU80720.2 - 3.3e-11 43.3 0.0 7.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EAU80720.2 - 9.4e-08 32.0 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Carn_acyltransf PF00755.20 EAU80725.2 - 1.6e-208 694.1 0.0 1.9e-208 693.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CLP1_P PF16575.5 EAU80730.2 - 2.5e-33 115.5 0.0 1.3e-26 93.6 0.0 2.7 3 0 0 3 3 3 2 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 EAU80730.2 - 0.00029 20.8 0.0 0.00065 19.7 0.0 1.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EAU80730.2 - 0.0011 19.0 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU80730.2 - 0.004 17.6 0.0 0.0085 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAU80730.2 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 EAU80732.2 - 2.2e-19 69.4 1.9 2.2e-19 69.4 1.9 1.8 2 0 0 2 2 2 1 DnaJ domain Hydrophobin PF01185.18 EAU80733.1 - 3.3e-26 91.7 11.4 3.9e-26 91.5 11.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin 5_nucleotid_C PF02872.18 EAU80734.1 - 2.4e-28 99.4 0.0 5.2e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EAU80734.1 - 3.6e-10 40.7 0.1 1e-09 39.2 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Piwi PF02171.17 EAU80736.2 - 8.2e-52 176.3 0.0 7.5e-45 153.4 0.0 2.8 2 1 1 3 3 3 2 Piwi domain ArgoN PF16486.5 EAU80736.2 - 6.3e-13 49.5 0.0 2e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EAU80736.2 - 9.4e-13 47.6 0.0 2.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 EAU80736.2 - 0.00061 20.0 0.0 0.0021 18.3 0.0 1.9 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 EAU80736.2 - 0.0035 17.2 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 PAZ domain VWA PF00092.28 EAU80736.2 - 0.028 14.7 0.0 19 5.5 0.0 3.2 2 1 1 3 3 3 0 von Willebrand factor type A domain ArgoL2 PF16488.5 EAU80736.2 - 0.044 14.1 0.0 0.3 11.4 0.0 2.5 2 1 0 2 2 2 0 Argonaute linker 2 domain Methyltransf_PK PF05891.12 EAU80736.2 - 0.2 11.2 0.0 0.6 9.6 0.0 1.8 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glyco_hydro_61 PF03443.14 EAU80738.1 - 5.7e-54 183.2 0.0 6.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 EAU80739.1 - 8.5e-54 182.6 0.0 1e-53 182.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BT1 PF03092.16 EAU80739.1 - 0.061 11.5 0.1 0.081 11.1 0.1 1.1 1 0 0 1 1 1 0 BT1 family Mur_ligase_M PF08245.12 EAU80740.2 - 0.00038 20.5 0.0 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain TOM6p PF15184.6 EAU80740.2 - 0.089 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog ABC_membrane PF00664.23 EAU80745.2 - 4.2e-104 348.0 18.2 1.2e-54 185.8 4.2 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAU80745.2 - 1.2e-56 191.0 0.0 7.6e-34 117.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 EAU80745.2 - 1.5e-06 27.8 5.2 0.029 14.1 0.0 3.7 4 0 0 4 4 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 EAU80745.2 - 4.3e-06 26.3 4.5 0.0023 17.4 0.0 3.8 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAU80745.2 - 8.5e-06 25.8 0.2 0.12 12.2 0.0 2.8 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EAU80745.2 - 9.5e-06 25.0 0.0 0.019 14.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 EAU80745.2 - 2.9e-05 24.4 0.9 0.29 11.4 0.0 3.5 3 1 0 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 EAU80745.2 - 3.2e-05 23.9 0.0 0.3 11.0 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EAU80745.2 - 3.4e-05 24.3 2.0 0.079 13.3 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 EAU80745.2 - 3.8e-05 23.6 0.0 0.21 11.3 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EAU80745.2 - 0.00056 19.7 4.8 1.1 8.9 0.1 4.0 4 0 0 4 4 4 2 AAA domain G-alpha PF00503.20 EAU80745.2 - 0.001 18.3 0.0 0.89 8.6 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 EAU80745.2 - 0.0026 17.4 0.1 2.2 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EAU80745.2 - 0.0037 17.8 0.0 1.7 9.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAU80745.2 - 0.0041 17.3 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EAU80745.2 - 0.0047 17.5 0.0 3.5 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EAU80745.2 - 0.0082 15.5 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family APS_kinase PF01583.20 EAU80745.2 - 0.012 15.5 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF815 PF05673.13 EAU80745.2 - 0.013 14.6 0.0 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EAU80745.2 - 0.018 14.6 0.0 8.1 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 EAU80745.2 - 0.031 14.4 0.5 5.1 7.1 0.3 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 EAU80745.2 - 0.034 14.1 0.0 5.2 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EAU80745.2 - 0.037 14.3 0.5 7.2 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 EAU80745.2 - 0.05 13.7 0.4 12 6.1 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF3987 PF13148.6 EAU80745.2 - 0.051 12.6 0.5 0.3 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) ABC_ATPase PF09818.9 EAU80745.2 - 0.061 12.1 0.1 0.31 9.8 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 EAU80745.2 - 0.077 12.7 0.1 13 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EAU80745.2 - 0.077 13.4 1.8 14 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 EAU80745.2 - 0.13 12.0 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 EAU80745.2 - 0.21 11.4 0.1 23 4.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SIR4_SID PF16991.5 EAU80746.1 - 0.2 11.7 2.4 0.4 10.7 2.4 1.4 1 0 0 1 1 1 0 Sir4 SID domain Ndc1_Nup PF09531.10 EAU80746.1 - 9.4 4.8 8.6 15 4.1 8.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EAU80746.1 - 9.7 5.3 18.7 14 4.8 18.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PP2C PF00481.21 EAU80748.2 - 2.7e-05 23.9 0.0 0.00024 20.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C CBM_14 PF01607.24 EAU80749.2 - 0.047 13.9 0.1 0.067 13.4 0.1 1.2 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain CBM_19 PF03427.13 EAU80749.2 - 0.082 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) ARF7EP_C PF14949.6 EAU80751.2 - 0.013 16.1 2.7 0.015 15.9 2.7 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Glyco_hydro_31 PF01055.26 EAU80752.2 - 2.6e-135 452.0 0.1 6.9e-95 318.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EAU80752.2 - 1.9e-38 131.2 0.1 3.8e-38 130.2 0.1 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EAU80752.2 - 2e-11 44.1 0.6 2e-11 44.1 0.6 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF2523 PF10734.9 EAU80753.2 - 0.047 14.3 0.3 0.096 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) DUF2835 PF11197.8 EAU80753.2 - 0.14 12.0 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Pkinase PF00069.25 EAU80755.2 - 9.9e-49 166.1 0.0 5.7e-48 163.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80755.2 - 1.4e-23 83.6 0.0 3.5e-23 82.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU80755.2 - 0.00068 18.5 0.1 0.0011 17.8 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase YL1 PF05764.13 EAU80755.2 - 0.0044 17.2 6.8 0.0044 17.2 6.8 2.0 2 0 0 2 2 2 1 YL1 nuclear protein Pox_ser-thr_kin PF05445.11 EAU80755.2 - 0.018 14.0 0.1 0.026 13.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EAU80755.2 - 0.07 12.5 0.3 0.16 11.3 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_polI_A34 PF08208.11 EAU80755.2 - 0.12 12.5 5.9 0.28 11.2 5.9 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 APH PF01636.23 EAU80755.2 - 0.12 12.2 0.2 0.51 10.2 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3381 PF11861.8 EAU80755.2 - 0.21 11.4 6.8 0.54 10.1 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) BUD22 PF09073.10 EAU80755.2 - 1.2 8.4 14.6 1.7 7.9 13.8 1.6 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 EAU80755.2 - 2.9 6.0 15.2 5.5 5.1 15.2 1.3 1 0 0 1 1 1 0 Nop14-like family GEN1_C PF18380.1 EAU80755.2 - 7.9 7.4 9.8 1.3 10.0 3.9 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain p450 PF00067.22 EAU80756.1 - 1.2e-64 218.8 0.0 1.4e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_18 PF00704.28 EAU80760.2 - 3.5e-84 283.2 0.0 4.2e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.25 EAU80763.1 - 3.5e-38 131.0 0.0 4.2e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU80763.1 - 2e-28 99.5 0.0 2.7e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU80763.1 - 2.2e-09 37.5 0.0 6.9e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EAU80763.1 - 0.018 14.9 0.1 0.039 13.8 0.0 1.5 2 0 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 EAU80763.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAU80763.1 - 0.06 12.3 0.0 0.64 9.0 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shugoshin_C PF07557.11 EAU80764.1 - 3.7e-09 36.2 5.1 3.7e-09 36.2 5.1 3.7 5 0 0 5 5 5 1 Shugoshin C terminus Shugoshin_N PF07558.11 EAU80764.1 - 2.8e-06 27.1 2.4 5.9e-06 26.1 2.4 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region GIT_CC PF16559.5 EAU80764.1 - 0.034 14.0 0.2 0.086 12.7 0.2 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 EAU80764.1 - 6.6 6.6 6.3 2 8.2 1.1 2.3 2 0 0 2 2 2 0 Septum formation initiator Hydrophobin PF01185.18 EAU80765.2 - 3.7e-20 72.3 7.8 4.5e-20 72.1 7.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Glyco_hydro_31 PF01055.26 EAU80766.2 - 9.5e-152 506.2 0.6 1.2e-151 505.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EAU80766.2 - 5.2e-37 126.6 0.1 1.2e-36 125.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EAU80766.2 - 5.4e-11 42.7 1.8 5.4e-11 42.7 1.8 2.5 3 0 0 3 3 3 1 Galactose mutarotase-like MMR_HSR1 PF01926.23 EAU80767.2 - 2.8e-08 33.8 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EAU80767.2 - 7.4e-06 25.5 0.0 2e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 Septin AIG1 PF04548.16 EAU80767.2 - 3.2e-05 23.4 0.0 9.5e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EAU80767.2 - 6.6e-05 22.9 0.2 0.00043 20.2 0.2 2.1 1 1 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EAU80767.2 - 0.00013 22.5 0.1 0.00051 20.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 EAU80767.2 - 0.00036 20.6 3.0 0.62 10.1 0.0 2.8 2 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EAU80767.2 - 0.0063 16.1 0.1 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAU80767.2 - 0.0093 16.4 0.4 0.27 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU80767.2 - 0.022 15.1 0.0 0.078 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EAU80767.2 - 0.027 14.2 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EAU80767.2 - 0.03 13.4 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EAU80767.2 - 0.034 14.7 3.1 0.12 12.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EAU80767.2 - 0.12 12.0 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EAU80767.2 - 0.22 11.3 0.3 12 5.5 0.1 2.6 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EAU80767.2 - 1.6 9.3 3.9 4.1 8.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain Vpu PF00558.19 EAU80768.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Vpu protein OAD_gamma PF04277.13 EAU80769.1 - 0.1 13.2 5.8 0.18 12.4 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain OppC_N PF12911.7 EAU80769.1 - 0.12 12.4 0.2 0.29 11.1 0.2 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Spore_YhaL PF14147.6 EAU80772.2 - 0.24 11.1 1.5 0.47 10.2 1.5 1.4 1 0 0 1 1 1 0 Sporulation protein YhaL zinc_ribbon_6 PF14599.6 EAU80779.2 - 0.079 13.0 1.2 0.079 13.0 1.2 2.7 3 0 0 3 3 3 0 Zinc-ribbon FAD_binding_4 PF01565.23 EAU80782.2 - 2e-22 79.4 0.3 3.3e-22 78.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU80782.2 - 1e-14 54.3 0.2 2e-14 53.4 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like RuBisCO_large PF00016.20 EAU80782.2 - 0.076 12.2 0.3 0.13 11.4 0.3 1.3 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Hydrophobin PF01185.18 EAU80783.1 - 5.2e-21 75.1 13.0 6.4e-21 74.8 13.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF3760 PF12586.8 EAU80784.1 - 0.042 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) zf-C2H2 PF00096.26 EAU80785.2 - 2e-08 34.2 10.2 3.9e-05 23.9 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU80785.2 - 0.00044 20.5 3.4 0.0016 18.8 3.4 2.0 1 0 0 1 1 1 1 Zinc-finger double domain Pkinase PF00069.25 EAU80789.2 - 8.1e-40 136.8 2.6 6.2e-17 61.8 0.0 3.5 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80789.2 - 4.5e-12 45.8 8.2 0.00021 20.7 0.3 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase PrmA PF06325.13 EAU80789.2 - 0.044 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_ser-thr_kin PF05445.11 EAU80789.2 - 0.24 10.3 0.1 0.4 9.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro_3_C PF01915.22 EAU80790.2 - 5.1e-61 206.2 0.0 7.4e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAU80790.2 - 6.5e-38 130.9 0.0 1e-37 130.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAU80790.2 - 6.4e-20 71.1 0.9 1.6e-19 69.8 0.7 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EAU80790.2 - 3e-12 46.6 0.0 6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PQQ PF01011.21 EAU80795.1 - 0.073 13.0 7.3 0.55 10.3 0.2 3.2 1 1 2 3 3 3 0 PQQ enzyme repeat VWA_3_C PF18571.1 EAU80795.1 - 0.27 11.1 4.5 13 5.7 0.2 3.3 1 1 2 3 3 3 0 von Willebrand factor type A C-terminal domain Mito_fiss_reg PF05308.11 EAU80802.2 - 0.38 10.8 2.7 0.41 10.7 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.16 EAU80804.2 - 3.6e-32 111.7 28.3 3.6e-32 111.7 28.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU80804.2 - 2.7e-08 33.1 13.0 2.7e-08 33.1 13.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PEN-2 PF10251.9 EAU80805.2 - 0.038 14.4 0.6 0.062 13.7 0.1 1.6 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase AflR PF08493.10 EAU80805.2 - 0.17 11.3 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein PKD PF00801.20 EAU80806.2 - 0.05 13.4 0.1 5.5 6.9 0.1 2.5 2 0 0 2 2 2 0 PKD domain Glyco_hydro_61 PF03443.14 EAU80807.2 - 9.4e-57 192.3 0.1 1.2e-56 191.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAU80807.2 - 4.1e-11 42.6 9.7 1.6e-10 40.7 9.7 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain zf-C2H2 PF00096.26 EAU80808.1 - 0.0032 17.8 0.1 0.0077 16.6 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF4764 PF15961.5 EAU80808.1 - 0.018 13.8 0.3 0.019 13.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_11 PF16622.5 EAU80808.1 - 0.092 12.5 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-MYND PF01753.18 EAU80810.2 - 8.1e-11 41.8 3.0 1.7e-10 40.8 3.0 1.6 1 0 0 1 1 1 1 MYND finger Amastin PF07344.11 EAU80812.2 - 0.0021 17.9 1.2 0.0039 17.1 1.2 1.5 1 0 0 1 1 1 1 Amastin surface glycoprotein FAD_binding_4 PF01565.23 EAU80813.2 - 1.8e-19 69.9 1.3 3.5e-19 68.9 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU80813.2 - 6.8e-09 35.7 0.1 1.3e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like TGT PF01702.18 EAU80814.2 - 7.5e-30 104.3 0.0 3.6e-10 39.5 0.0 3.4 3 1 0 3 3 3 3 Queuine tRNA-ribosyltransferase Tyr-DNA_phospho PF06087.12 EAU80814.2 - 0.23 10.3 2.4 1.7 7.5 0.1 2.1 2 0 0 2 2 2 0 Tyrosyl-DNA phosphodiesterase Peptidase_M28 PF04389.17 EAU80818.1 - 8.9e-39 133.2 0.0 1.2e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAU80818.1 - 2.9e-12 46.5 0.2 6e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EAU80818.1 - 0.00087 19.0 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Gpr1_Fun34_YaaH PF01184.19 EAU80823.1 - 9.3e-47 159.3 16.6 1.1e-46 159.1 16.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Filo_glycop PF01611.16 EAU80823.1 - 0.12 11.3 0.7 0.15 11.0 0.7 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein DEC-1_N PF04625.13 EAU80823.1 - 0.24 10.4 3.6 0.29 10.1 3.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ATG101 PF07855.12 EAU80824.2 - 1.9e-17 63.6 1.0 2.1e-17 63.5 1.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 PHD PF00628.29 EAU80825.2 - 3.7e-06 26.7 5.7 2.4e-05 24.2 2.5 2.3 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 EAU80825.2 - 0.0013 18.6 3.4 0.0013 18.6 3.4 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Reg_prop PF07494.11 EAU80825.2 - 0.071 13.4 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Two component regulator propeller zf-RING_9 PF13901.6 EAU80825.2 - 0.073 13.0 1.4 0.13 12.2 1.4 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zinc_ribbon_4 PF13717.6 EAU80825.2 - 0.15 12.0 4.2 0.25 11.3 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TerY_C PF15616.6 EAU80825.2 - 0.43 10.7 2.7 0.24 11.5 0.7 1.5 2 0 0 2 2 2 0 TerY-C metal binding domain MFS_1 PF07690.16 EAU80827.1 - 1.2e-30 106.7 31.6 1.6e-30 106.2 31.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU80827.1 - 1.9e-10 40.2 4.2 1.9e-10 40.2 4.2 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EAU80827.1 - 0.18 10.1 2.8 0.51 8.6 0.4 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pol_alpha_B_N PF08418.10 EAU80828.2 - 0.0037 17.3 3.6 0.0037 17.3 3.6 2.3 1 1 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal RAP1 PF07218.11 EAU80828.2 - 1.9 6.7 5.2 3.3 5.9 5.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Plavaka PF18759.1 EAU80829.2 - 2.3e-111 372.1 0.0 3.2e-111 371.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase PIF1 PF05970.14 EAU80832.2 - 1.8e-29 103.1 0.0 9.2e-29 100.7 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EAU80832.2 - 4.5e-23 82.5 0.0 1.4e-22 80.9 0.0 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAU80832.2 - 1.3e-09 38.1 0.0 3.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU80832.2 - 0.00026 21.4 0.0 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 EAU80832.2 - 0.01 13.8 0.0 0.018 13.0 0.0 1.3 1 0 0 1 1 1 1 Helicase NB-ARC PF00931.22 EAU80832.2 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EAU80832.2 - 1.8 8.9 7.4 0.34 11.3 0.1 3.4 4 1 0 4 4 4 0 AAA ATPase domain Peptidase_M28 PF04389.17 EAU80838.1 - 5.7e-35 120.8 0.0 8.7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAU80838.1 - 1.9e-11 43.8 0.1 4.4e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EAU80838.1 - 0.0016 18.2 0.0 0.0052 16.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.16 EAU80839.2 - 1.6e-09 37.2 21.8 1.6e-09 37.2 21.8 4.1 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 EAU80839.2 - 0.014 13.7 0.1 0.014 13.7 0.1 2.1 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DLP_helical PF18709.1 EAU80845.1 - 0.0081 15.4 0.8 0.011 15.0 0.8 1.1 1 0 0 1 1 1 1 Dynamin-like helical domain Aminotran_1_2 PF00155.21 EAU80845.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II GRIN_C PF15235.6 EAU80845.1 - 0.26 11.5 2.3 0.65 10.2 2.3 2.0 1 1 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus MukF_M PF17192.4 EAU80848.2 - 0.082 12.6 1.2 2 8.1 0.0 2.8 3 0 0 3 3 3 0 MukF middle domain CRF1 PF10380.9 EAU80849.1 - 0.18 12.1 0.4 2.8 8.3 0.0 2.2 1 1 1 2 2 2 0 Transcription factor CRF1 Asp PF00026.23 EAU80857.2 - 2.5e-32 112.6 0.0 3.1e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU80857.2 - 0.0085 16.3 0.1 0.029 14.6 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal LapA_dom PF06305.11 EAU80857.2 - 0.031 14.1 1.9 0.067 13.0 1.9 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 EAU80857.2 - 0.24 10.1 0.0 0.36 9.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Motilin_ghrelin PF04644.12 EAU80857.2 - 0.82 9.5 4.6 3.1 7.7 1.7 2.4 2 0 0 2 2 2 0 Motilin/ghrelin DUF3043 PF11241.8 EAU80858.2 - 0.19 11.8 7.0 0.27 11.3 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) F-box-like PF12937.7 EAU80859.2 - 0.012 15.5 0.4 0.054 13.4 0.1 2.1 2 0 0 2 2 2 0 F-box-like EB1 PF03271.17 EAU80860.1 - 2.2e-16 59.8 4.7 4.1e-16 58.9 4.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EAU80860.1 - 0.00049 20.3 0.6 0.0011 19.2 0.3 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 EAU80860.1 - 0.015 13.9 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Suppressor_APC PF11414.8 EAU80860.1 - 0.11 12.5 1.3 0.23 11.5 1.3 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein LMP PF04778.12 EAU80860.1 - 0.12 12.3 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 LMP repeated region FlxA PF14282.6 EAU80860.1 - 0.32 11.0 2.6 0.53 10.3 2.6 1.4 1 1 0 1 1 1 0 FlxA-like protein SUIM_assoc PF16619.5 EAU80860.1 - 0.33 11.0 2.0 0.6 10.2 2.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 EAU80861.2 - 3.1e-15 56.0 35.2 2.7e-11 43.0 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PSK_trans_fac PF07704.11 EAU80863.1 - 0.077 13.8 0.2 0.077 13.8 0.2 3.2 3 0 0 3 3 3 0 Rv0623-like transcription factor Hydin_ADK PF17213.3 EAU80863.1 - 1.9 8.7 6.3 1.7 8.9 4.9 1.5 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain Phage_lysozyme PF00959.19 EAU80864.1 - 4.6e-18 65.7 0.0 6.8e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme NAAA-beta PF15508.6 EAU80865.2 - 1.1e-13 51.3 0.0 5.5e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Phage_lysozyme PF00959.19 EAU80866.1 - 2.1e-18 66.8 0.0 3.1e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme zf-RING_2 PF13639.6 EAU80868.2 - 9.4e-13 48.3 6.1 1.5e-12 47.6 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU80868.2 - 1.6e-08 34.3 5.5 2.6e-08 33.6 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU80868.2 - 3.9e-08 33.5 6.7 8e-08 32.5 6.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAU80868.2 - 5.9e-08 32.3 3.8 1.1e-07 31.4 3.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EAU80868.2 - 1.1e-07 31.6 5.2 1.8e-07 30.9 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU80868.2 - 3e-06 27.1 4.4 4.7e-06 26.4 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAU80868.2 - 9.4e-06 25.4 3.7 1.5e-05 24.7 3.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAU80868.2 - 2.8e-05 24.1 2.0 5.4e-05 23.2 2.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EAU80868.2 - 0.00042 20.3 4.2 0.00082 19.4 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EAU80868.2 - 0.0037 17.0 6.7 0.0065 16.2 6.7 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EAU80868.2 - 0.0042 16.9 3.6 0.0072 16.2 3.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EAU80868.2 - 0.0061 16.2 5.2 0.011 15.4 5.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EAU80868.2 - 0.02 15.2 3.8 0.039 14.3 3.8 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EAU80868.2 - 0.072 13.2 6.2 0.13 12.4 6.2 1.4 1 0 0 1 1 1 0 RING-variant domain Nop14 PF04147.12 EAU80868.2 - 0.12 10.6 23.7 0.075 11.2 18.9 2.1 2 0 0 2 2 2 0 Nop14-like family zf-C3HC4_5 PF17121.5 EAU80868.2 - 0.18 11.7 2.7 0.37 10.7 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EAU80868.2 - 1.5 9.1 4.0 3.1 8.0 4.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EAU80868.2 - 2 8.4 6.7 3.5 7.6 6.7 1.4 1 0 0 1 1 1 0 PHD-finger MFS_1 PF07690.16 EAU80869.2 - 1.6e-26 93.1 40.9 2.3e-24 86.0 32.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EAU80869.2 - 5.8e-06 25.8 7.6 5.8e-06 25.8 7.6 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Phage_lysozyme PF00959.19 EAU80871.2 - 1.2e-14 54.6 0.0 1.8e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme MPS2 PF17060.5 EAU80872.2 - 0.2 10.9 0.1 0.36 10.0 0.1 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Phage_lysozyme PF00959.19 EAU80873.1 - 5e-15 55.9 0.0 7.5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme BTB PF00651.31 EAU80874.2 - 5.4e-07 29.8 0.0 1.5e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EAU80875.2 - 8e-08 32.5 0.0 2.1e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Abhydrolase_1 PF00561.20 EAU80876.2 - 0.049 13.3 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_61 PF03443.14 EAU80877.2 - 1.6e-39 136.0 0.0 2e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 VCBS PF13517.6 EAU80877.2 - 0.024 15.2 0.9 0.22 12.1 0.0 2.7 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4139 PF13598.6 EAU80878.2 - 4.6e-54 183.3 0.0 9.6e-52 175.7 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EAU80878.2 - 4.1e-27 94.5 4.3 7.2e-26 90.5 0.1 2.6 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EAU80878.2 - 1.5e-05 24.1 1.9 2.4e-05 23.4 1.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein V_ATPase_I PF01496.19 EAU80878.2 - 0.035 12.0 0.4 0.046 11.6 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI3K_P85_iSH2 PF16454.5 EAU80878.2 - 0.078 12.6 5.1 1.8 8.1 0.3 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FAA_hydro_N_2 PF18288.1 EAU80878.2 - 0.08 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 ATG16 PF08614.11 EAU80878.2 - 0.13 12.5 2.8 0.2 11.8 2.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 EAU80878.2 - 0.16 12.4 1.4 0.35 11.3 1.4 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF5082 PF16888.5 EAU80878.2 - 0.25 11.6 2.5 0.57 10.5 2.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Snapin_Pallidin PF14712.6 EAU80878.2 - 0.54 10.7 2.7 1.1 9.7 0.6 2.2 1 1 2 3 3 3 0 Snapin/Pallidin DUF848 PF05852.11 EAU80878.2 - 0.97 9.5 3.3 1.8 8.6 3.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 EAU80878.2 - 4.7 7.2 7.1 35 4.4 7.1 2.1 1 1 0 1 1 1 0 Prefoldin subunit Trypan_PARP PF05887.11 EAU80881.1 - 0.0053 16.7 9.0 0.0053 16.7 9.0 5.3 6 0 0 6 6 6 1 Procyclic acidic repetitive protein (PARP) ETF PF01012.21 EAU80882.1 - 2.1e-27 96.2 0.3 2.5e-27 95.9 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Pro_CA PF00484.19 EAU80883.2 - 1.2e-30 106.9 0.0 2.5e-29 102.6 0.0 2.2 1 1 0 1 1 1 1 Carbonic anhydrase BTB PF00651.31 EAU80884.1 - 1.7e-08 34.7 0.1 6.2e-08 32.8 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Ndc1_Nup PF09531.10 EAU80884.1 - 0.036 12.8 0.3 0.038 12.7 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zn_Tnp_IS1595 PF12760.7 EAU80884.1 - 0.037 14.0 0.2 0.037 14.0 0.2 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain HHH PF00633.23 EAU80884.1 - 0.14 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pex14_N PF04695.13 EAU80884.1 - 0.55 10.9 10.7 1.1 9.9 10.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase_fungal PF17667.1 EAU80886.2 - 4.3e-20 71.9 0.0 7.2e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU80886.2 - 5.9e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80886.2 - 0.00019 20.8 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU80887.2 - 2.2e-23 82.7 0.1 3e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU80887.2 - 3.6e-08 33.1 0.0 4.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80887.2 - 2.8e-05 23.5 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU80888.2 - 3.9e-21 75.3 0.0 5.1e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU80888.2 - 5.9e-06 25.8 0.0 8.4e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU80888.2 - 0.00087 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase BTB PF00651.31 EAU80889.1 - 2e-08 34.4 0.0 6.3e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain DUF4139 PF13598.6 EAU80890.1 - 2.2e-53 181.1 0.0 4.4e-51 173.5 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EAU80890.1 - 4.6e-24 84.7 2.0 1.2e-21 76.9 2.0 2.7 1 1 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 EAU80890.1 - 0.014 14.3 1.1 0.022 13.6 1.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein KASH_CCD PF14662.6 EAU80890.1 - 0.031 14.1 0.4 0.049 13.5 0.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Snapin_Pallidin PF14712.6 EAU80890.1 - 0.039 14.4 0.5 0.11 13.0 0.5 1.7 1 0 0 1 1 1 0 Snapin/Pallidin CBM_35 PF16990.5 EAU80890.1 - 0.098 12.9 0.1 3.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Carbohydrate binding module (family 35) PI3K_P85_iSH2 PF16454.5 EAU80890.1 - 0.58 9.7 3.3 1 9.0 1.1 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Glyco_hydro_61 PF03443.14 EAU80891.2 - 4.8e-34 118.1 0.0 9.8e-34 117.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 VCBS PF13517.6 EAU80891.2 - 0.14 12.8 3.7 0.39 11.3 1.7 2.5 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Abhydrolase_6 PF12697.7 EAU80892.1 - 1.7e-10 41.9 6.2 1.7e-10 41.9 6.2 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU80892.1 - 8.9e-09 35.4 0.0 8.9e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold CMD PF02627.20 EAU80892.1 - 7e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Hydrolase_4 PF12146.8 EAU80892.1 - 0.011 15.1 0.1 0.032 13.5 0.1 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 TIR_3 PF18567.1 EAU80893.2 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain UQ_con PF00179.26 EAU80894.2 - 1.4e-39 134.9 0.0 1.9e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EAU80894.2 - 2.5e-18 65.6 0.0 3.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EAU80894.2 - 0.0068 16.1 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_6 PF18039.1 EAU80894.2 - 0.041 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain ArfGap PF01412.18 EAU80895.2 - 1.4e-32 112.2 0.9 3.3e-32 111.0 0.9 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GEN1_C PF18380.1 EAU80898.1 - 1.9e-26 93.0 0.0 1.9e-26 93.0 0.0 3.3 4 1 0 4 4 4 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EAU80898.1 - 7.4e-18 64.7 0.0 2e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EAU80898.1 - 0.00012 22.5 0.0 0.0004 20.8 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain BTB PF00651.31 EAU80899.1 - 4.8e-06 26.8 0.0 9.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Phage_lysozyme PF00959.19 EAU80900.1 - 1.1e-18 67.6 0.0 2.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Phage lysozyme DUF4139 PF13598.6 EAU80901.1 - 1.1e-49 169.0 0.0 1e-48 165.8 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EAU80901.1 - 1e-21 77.2 4.3 1.8e-21 76.4 0.2 2.9 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) DHR10 PF18595.1 EAU80901.1 - 2.3 8.3 7.8 3.9 7.6 7.8 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF202 PF02656.15 EAU80903.1 - 8.4e-17 61.4 0.4 8.4e-17 61.4 0.4 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF1685 PF07939.11 EAU80905.2 - 0.047 13.4 0.1 4.5 7.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1685) MFS_1 PF07690.16 EAU80906.2 - 2.3e-22 79.4 40.4 1.5e-19 70.2 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TPP_enzyme_N PF02776.18 EAU80907.1 - 6.7e-33 113.7 0.1 1.4e-32 112.7 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EAU80907.1 - 3.6e-12 46.3 0.2 9e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAU80907.1 - 0.00033 20.4 0.0 0.0054 16.5 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain F-box-like PF12937.7 EAU80908.2 - 0.027 14.4 0.0 0.094 12.6 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EAU80908.2 - 0.089 12.7 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 F-box domain Clat_adaptor_s PF01217.20 EAU80909.1 - 2.8e-56 189.4 3.6 3.1e-56 189.3 3.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 EAU80909.1 - 0.038 13.6 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Ferric_reduct PF01794.19 EAU80911.1 - 1.7e-21 76.6 16.3 4.9e-21 75.1 16.3 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAU80911.1 - 2.1e-05 24.7 0.2 0.029 14.5 0.1 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAU80911.1 - 0.00078 19.5 0.3 0.0049 16.9 0.3 2.2 1 1 0 1 1 1 1 FAD-binding domain DUF2427 PF10348.9 EAU80911.1 - 0.32 10.8 4.0 0.17 11.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) CPBP PF02517.16 EAU80912.2 - 0.00058 20.2 3.8 0.00063 20.1 0.5 2.3 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Pyr_redox_2 PF07992.14 EAU80914.1 - 1.1e-12 47.8 0.0 2.8e-12 46.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU80914.1 - 2.6e-10 40.1 0.2 0.00017 20.9 0.1 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU80914.1 - 3.6e-09 36.7 1.0 5.9e-07 29.6 0.1 3.4 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EAU80914.1 - 3.8e-09 36.1 0.5 1.5e-07 30.9 0.0 2.8 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EAU80914.1 - 6.1e-09 36.1 0.0 0.016 15.2 0.0 3.9 4 0 0 4 4 4 2 FAD-NAD(P)-binding FMO-like PF00743.19 EAU80914.1 - 8.7e-07 27.7 0.0 8.5e-06 24.5 0.0 2.5 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 EAU80914.1 - 1.5e-06 28.6 0.1 0.098 13.1 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.20 EAU80914.1 - 3e-06 27.3 0.3 0.092 12.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EAU80914.1 - 5.9e-06 26.7 1.2 0.00018 22.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU80914.1 - 2.7e-05 23.9 8.7 0.00087 19.0 0.3 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAU80914.1 - 9.5e-05 21.8 1.2 0.0028 17.0 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 EAU80914.1 - 0.0015 17.7 2.2 0.0069 15.5 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 EAU80914.1 - 0.0016 17.6 0.7 2.1 7.3 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.22 EAU80914.1 - 0.0018 17.4 0.5 0.22 10.6 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EAU80914.1 - 0.002 17.5 0.0 0.047 13.0 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EAU80914.1 - 0.0029 16.9 0.7 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Glu_dehyd_C PF16912.5 EAU80914.1 - 0.0073 15.8 0.0 0.026 14.0 0.0 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 EAU80914.1 - 0.032 13.0 0.1 0.032 13.0 0.1 2.5 4 0 0 4 4 4 0 HI0933-like protein 3HCDH_N PF02737.18 EAU80914.1 - 0.037 13.9 0.8 0.73 9.7 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EAU80914.1 - 0.09 13.0 0.2 9.6 6.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 EAU80914.1 - 0.098 12.3 0.2 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA YjeF_N PF03853.15 EAU80914.1 - 0.11 12.4 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus VCBS PF13517.6 EAU80915.2 - 4.7e-20 71.9 28.9 5.7e-06 26.8 3.6 5.4 3 2 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BTB PF00651.31 EAU80916.2 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain SPX PF03105.19 EAU80916.2 - 0.0083 16.1 2.4 0.01 15.8 2.4 1.2 1 0 0 1 1 1 1 SPX domain SpoIIIAH PF12685.7 EAU80916.2 - 0.033 14.0 2.0 0.046 13.5 2.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Macoilin PF09726.9 EAU80916.2 - 0.04 12.5 8.0 0.055 12.0 8.0 1.1 1 0 0 1 1 1 0 Macoilin family RRN3 PF05327.11 EAU80916.2 - 0.084 11.4 1.8 0.12 10.9 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EAU80916.2 - 0.12 10.7 3.1 0.16 10.3 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein IFRD PF05004.13 EAU80916.2 - 0.32 10.0 9.0 0.52 9.4 9.0 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Sec3_C PF09763.9 EAU80916.2 - 0.9 7.8 2.9 1.2 7.4 2.9 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Apt1 PF10351.9 EAU80916.2 - 1.2 7.9 8.8 1.6 7.5 8.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4698 PF15769.5 EAU80916.2 - 1.5 7.8 3.9 2 7.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Nop14 PF04147.12 EAU80916.2 - 2.1 6.5 7.3 2.9 6.0 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EAU80916.2 - 3.1 5.8 11.9 4.6 5.2 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi RAP1 PF07218.11 EAU80916.2 - 3.5 5.8 11.9 4.5 5.4 11.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BTB PF00651.31 EAU80918.2 - 0.028 14.6 0.0 0.081 13.2 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain Chitin_synth_1 PF01644.17 EAU80919.2 - 4.2e-79 264.2 0.1 5.9e-79 263.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EAU80919.2 - 8.4e-29 99.3 0.0 2.9e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EAU80919.2 - 2.6e-23 82.4 0.8 5.2e-17 61.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAU80919.2 - 0.039 13.9 19.9 1.5 8.7 19.9 2.8 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Pkinase PF00069.25 EAU80920.1 - 1.8e-07 30.8 0.0 3.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAU80920.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EAU80920.1 - 0.0016 17.8 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU80920.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MMR_HSR1 PF01926.23 EAU80922.1 - 9.1e-11 41.9 0.2 1.7e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EAU80922.1 - 4e-07 30.3 0.0 7.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EAU80922.1 - 8.9e-07 29.1 0.1 2.9e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 Dynamin family AIG1 PF04548.16 EAU80922.1 - 1.8e-06 27.5 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 EAU80922.1 - 5.3e-05 22.9 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EAU80922.1 - 0.00015 21.7 0.1 0.0003 20.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EAU80922.1 - 0.00026 21.5 0.1 0.0012 19.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter IIGP PF05049.13 EAU80922.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 EAU80922.1 - 0.0018 17.8 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EAU80922.1 - 0.0035 17.6 0.1 0.013 15.7 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU80922.1 - 0.0097 16.3 0.2 0.025 15.0 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EAU80922.1 - 0.027 14.8 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 EAU80922.1 - 0.044 13.1 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 EAU80922.1 - 0.12 12.8 0.5 0.23 12.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EAU80922.1 - 0.13 11.7 0.0 0.56 9.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 EAU80922.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family WD40 PF00400.32 EAU80927.2 - 2.6e-72 236.9 41.7 1.5e-10 41.4 0.0 14.8 14 0 0 14 14 14 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU80927.2 - 4.4e-31 107.0 0.0 0.00078 19.7 0.0 12.3 1 1 12 13 13 13 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU80927.2 - 1.6e-07 30.6 0.0 1.1 8.1 0.0 6.7 2 1 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 EAU80927.2 - 3e-07 30.5 0.0 5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU80927.2 - 2.1e-05 24.9 0.0 5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ChapFlgA PF13144.6 EAU80927.2 - 7.3e-05 22.8 0.0 35 4.5 0.0 5.3 4 2 2 6 6 6 0 Chaperone for flagella basal body P-ring formation AAA_22 PF13401.6 EAU80927.2 - 0.00089 19.6 0.0 0.0024 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF5046 PF16465.5 EAU80927.2 - 0.0029 17.1 0.0 15 5.0 0.0 3.8 1 1 1 3 3 3 0 Domain of unknown function (DUF5046) Nup160 PF11715.8 EAU80927.2 - 0.0075 15.0 0.4 18 3.8 0.0 4.8 2 1 3 6 6 6 0 Nucleoporin Nup120/160 NB-ARC PF00931.22 EAU80927.2 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PD40 PF07676.12 EAU80927.2 - 0.028 14.4 0.3 11 6.1 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EAU80927.2 - 0.038 13.7 3.3 7.8 6.3 0.0 5.4 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature PIF1 PF05970.14 EAU80927.2 - 0.07 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_33 PF13671.6 EAU80927.2 - 0.16 12.1 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU80927.2 - 0.2 12.1 0.0 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Complex1_51K PF01512.17 EAU80928.1 - 1.5e-48 164.5 0.0 2.8e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EAU80928.1 - 2.9e-32 110.6 1.3 5.3e-32 109.7 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EAU80928.1 - 2.7e-08 33.6 0.0 6.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EAU80928.1 - 0.2 11.7 0.6 0.38 10.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) RCDG1 PF15725.5 EAU80928.1 - 4.1 7.9 5.9 4.3 7.8 3.1 2.3 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein Methyltransf_10 PF05971.12 EAU80929.2 - 5.7e-25 88.3 1.0 2.1e-13 50.3 0.0 3.3 2 1 1 3 3 3 3 RNA methyltransferase ABC_tran_CTD PF16326.5 EAU80929.2 - 0.017 15.4 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain MTS PF05175.14 EAU80929.2 - 0.14 11.7 0.0 0.32 10.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_15 PF00723.21 EAU80931.2 - 6.6e-20 71.3 0.0 1.3e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 BTB PF00651.31 EAU80932.2 - 0.00036 20.7 0.0 0.00065 19.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-H2C2_5 PF13909.6 EAU80933.2 - 0.0044 16.7 0.8 0.0044 16.7 0.8 2.0 2 0 0 2 2 2 1 C2H2-type zinc-finger domain SpdB PF05122.13 EAU80933.2 - 0.099 12.8 0.6 0.099 12.8 0.6 2.2 2 0 0 2 2 2 0 Mobile element transfer protein F1F0-ATPsyn_F PF10791.9 EAU80934.1 - 2.6e-29 101.5 0.0 3e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Gpi16 PF04113.14 EAU80935.2 - 3.1e-136 455.1 4.1 1.2e-134 449.8 4.1 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component AAA PF00004.29 EAU80936.2 - 1.9e-83 277.4 0.0 1.1e-40 139.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU80936.2 - 3.7e-25 87.5 0.2 9.5e-14 50.9 0.2 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EAU80936.2 - 1.5e-12 47.6 0.0 0.00063 19.5 0.0 3.6 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EAU80936.2 - 1.2e-11 44.8 0.0 1.3e-05 25.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU80936.2 - 1.7e-11 44.8 1.6 1.8e-05 25.2 0.1 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EAU80936.2 - 1.5e-10 41.4 0.0 0.00048 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAU80936.2 - 4.6e-08 33.3 0.0 0.00028 21.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EAU80936.2 - 5.2e-08 33.3 0.8 0.0012 19.1 0.0 4.5 3 2 1 4 4 3 1 AAA domain IstB_IS21 PF01695.17 EAU80936.2 - 7.5e-08 32.3 0.0 0.0009 19.0 0.0 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EAU80936.2 - 2.9e-07 30.0 0.0 0.0072 15.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EAU80936.2 - 1.2e-05 25.3 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EAU80936.2 - 0.00012 22.1 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EAU80936.2 - 0.00014 21.2 0.0 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 EAU80936.2 - 0.00019 20.9 0.1 0.21 11.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAU80936.2 - 0.00026 21.3 0.0 0.062 13.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_11 PF13086.6 EAU80936.2 - 0.0007 19.5 0.0 0.021 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAU80936.2 - 0.00074 19.1 3.7 3.8 7.0 0.0 4.3 2 2 2 4 4 4 1 AAA domain AAA_18 PF13238.6 EAU80936.2 - 0.00091 19.8 0.0 0.013 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU80936.2 - 0.00099 19.1 0.8 0.062 13.2 0.0 3.4 4 0 0 4 4 4 1 NACHT domain AAA_28 PF13521.6 EAU80936.2 - 0.0011 19.3 0.0 0.14 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAU80936.2 - 0.0013 18.3 0.0 0.7 9.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 EAU80936.2 - 0.0037 17.0 0.0 0.077 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EAU80936.2 - 0.0038 17.2 0.5 1.3 8.9 0.1 3.4 2 2 1 3 3 3 1 Rad17 P-loop domain Sigma54_activat PF00158.26 EAU80936.2 - 0.0054 16.5 0.0 0.89 9.2 0.0 3.3 2 1 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EAU80936.2 - 0.0055 16.5 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 EAU80936.2 - 0.0057 16.5 0.0 0.22 11.3 0.0 2.9 2 1 0 2 2 2 1 Bacterial dnaA protein ATPase_2 PF01637.18 EAU80936.2 - 0.0057 16.6 0.1 9.3 6.1 0.0 3.6 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EAU80936.2 - 0.0062 16.4 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 EAU80936.2 - 0.018 14.2 0.0 0.08 12.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.27 EAU80936.2 - 0.021 15.3 0.0 0.51 10.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Vps4_C PF09336.10 EAU80936.2 - 0.024 14.6 0.1 0.27 11.2 0.0 2.7 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 EAU80936.2 - 0.029 13.8 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EAU80936.2 - 0.03 13.5 0.1 2 7.6 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Parvo_NS1 PF01057.17 EAU80936.2 - 0.062 12.4 0.0 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 EAU80936.2 - 0.065 13.6 0.3 0.53 10.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAU80936.2 - 0.08 12.6 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EAU80936.2 - 0.095 12.0 0.0 7.5 5.8 0.0 2.5 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 EAU80936.2 - 0.1 12.7 0.0 9.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 EAU80936.2 - 0.12 11.2 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase DUF815 PF05673.13 EAU80936.2 - 0.13 11.4 0.0 3 6.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EAU80936.2 - 0.13 12.2 0.3 3.3 7.6 0.0 3.2 3 2 1 4 4 4 0 NTPase Adeno_IVa2 PF02456.15 EAU80936.2 - 0.27 10.0 0.1 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein adh_short PF00106.25 EAU80937.1 - 1e-38 132.8 0.0 1.4e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU80937.1 - 1.5e-28 99.9 0.0 2e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EAU80937.1 - 8.1e-08 32.0 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EAU80937.1 - 1.8e-05 24.8 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU80937.1 - 0.005 16.3 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAU80937.1 - 0.11 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EAU80937.1 - 0.18 11.3 0.2 0.27 10.8 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Kelch_6 PF13964.6 EAU80938.2 - 9.9e-15 54.2 11.8 2.8e-06 27.4 0.1 7.2 7 1 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 EAU80938.2 - 1.5e-11 44.0 2.6 0.058 13.4 0.1 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EAU80938.2 - 4.7e-09 36.1 6.9 0.44 10.6 0.0 6.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EAU80938.2 - 4.7e-06 26.8 9.3 0.26 11.6 0.0 6.1 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EAU80938.2 - 6.2e-06 26.0 3.0 0.05 13.6 0.0 5.4 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 EAU80938.2 - 3.8e-05 23.2 7.2 0.25 10.9 0.0 5.2 7 0 0 7 7 7 2 Kelch motif zf-MYND PF01753.18 EAU80938.2 - 0.00043 20.3 8.3 0.00083 19.4 8.3 1.5 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 EAU80938.2 - 0.018 15.1 0.0 0.6 10.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 EAU80938.2 - 0.027 14.8 9.3 0.074 13.4 9.3 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Shadoo PF14999.6 EAU80938.2 - 0.15 12.2 6.8 0.41 10.7 6.8 1.7 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TPR_1 PF00515.28 EAU80938.2 - 0.17 11.8 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat NACHT PF05729.12 EAU80940.1 - 2.4e-09 37.3 0.0 4.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU80940.1 - 2.9e-06 27.8 0.1 6e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAU80940.1 - 0.00066 19.4 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU80940.1 - 0.0025 18.1 0.0 0.0075 16.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EAU80940.1 - 0.0074 16.4 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EAU80940.1 - 0.093 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 EAU80940.1 - 0.11 13.0 1.8 1.2 9.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAU80940.1 - 0.12 12.7 0.2 0.45 10.9 0.1 2.0 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EAU80940.1 - 0.13 12.8 0.0 0.75 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Tae4 PF14113.6 EAU80940.1 - 0.21 11.8 0.0 0.49 10.6 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 cwf21 PF08312.12 EAU80940.1 - 1.7 8.8 4.5 7.4 6.8 4.5 2.1 1 1 0 1 1 1 0 cwf21 domain FAD_binding_3 PF01494.19 EAU80941.1 - 3.2e-10 39.8 0.0 0.0013 18.1 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.24 EAU80941.1 - 0.0081 15.8 0.2 0.02 14.5 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAU80941.1 - 0.0086 16.1 0.3 0.093 12.7 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EAU80941.1 - 0.016 15.4 0.1 0.037 14.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EAU80941.1 - 0.084 11.7 0.2 3.2 6.5 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase DSPc PF00782.20 EAU80942.1 - 3e-31 108.0 0.0 3.6e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EAU80942.1 - 7.6e-05 23.0 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EAU80942.1 - 0.035 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Glu_syn_central PF04898.14 EAU80942.1 - 0.11 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Myotub-related PF06602.14 EAU80942.1 - 0.21 10.5 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain SE PF08491.10 EAU80943.1 - 1.5e-82 276.7 0.0 2e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EAU80943.1 - 4.2e-08 33.2 0.1 9.6e-06 25.4 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAU80943.1 - 4e-06 26.3 0.2 6.4e-05 22.3 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EAU80943.1 - 0.00011 21.2 0.2 0.0015 17.5 0.4 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EAU80943.1 - 0.0004 19.7 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU80943.1 - 0.00049 19.3 0.8 0.0011 18.1 0.1 1.9 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU80943.1 - 0.0025 18.0 0.6 0.0047 17.1 0.6 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU80943.1 - 0.012 14.7 0.9 0.02 14.0 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EAU80943.1 - 0.023 14.7 0.1 0.075 13.1 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EAU80943.1 - 0.024 14.9 0.2 0.041 14.2 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 EAU80943.1 - 0.076 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EAU80943.1 - 0.15 11.9 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EAU80943.1 - 0.16 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EAU80943.1 - 0.17 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 EAU80943.1 - 0.17 10.9 1.5 0.15 11.1 0.4 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_hydro_61 PF03443.14 EAU80944.1 - 5.3e-43 147.4 0.1 9.2e-43 146.6 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Mannosidase_ig PF17786.1 EAU80945.1 - 3.5e-16 59.6 0.0 8.1e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 EAU80945.1 - 0.00034 20.3 0.0 0.00073 19.2 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EAU80945.1 - 0.00092 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EAU80945.1 - 0.00098 19.8 0.0 0.003 18.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Peptidase_S8 PF00082.22 EAU80946.2 - 1e-14 54.5 8.2 1.5e-14 54.0 8.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAU80946.2 - 0.0058 17.3 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DLH PF01738.18 EAU80947.2 - 5.2e-19 68.7 0.0 2.4e-15 56.7 0.1 2.0 2 0 0 2 2 2 2 Dienelactone hydrolase family BNIP3 PF06553.12 EAU80948.1 - 0.0035 17.1 0.3 0.0081 15.9 0.3 1.6 1 0 0 1 1 1 1 BNIP3 Mhr1 PF12829.7 EAU80948.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination SWIRM-assoc_2 PF16496.5 EAU80948.1 - 8.6 5.1 9.3 9.1 5.0 1.2 2.1 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal LRR_4 PF12799.7 EAU80949.2 - 0.13 12.7 8.8 3.9 8.0 0.2 4.8 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) EZH2_WD-Binding PF11616.8 EAU80950.2 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 WD repeat binding protein EZH2 WD40 PF00400.32 EAU80951.2 - 3.2e-44 148.0 6.7 4.3e-11 43.2 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU80951.2 - 5.1e-11 42.7 0.0 0.00071 19.8 0.0 4.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EAU80951.2 - 4.5e-10 39.7 0.1 2.2e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 EAU80951.2 - 7.4e-06 25.2 0.0 0.13 11.2 0.0 3.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EAU80951.2 - 0.00072 20.0 0.0 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EAU80951.2 - 0.012 16.1 0.1 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAU80951.2 - 0.014 15.6 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU80951.2 - 0.052 14.1 0.0 0.2 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU80951.2 - 0.073 13.5 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Tae4 PF14113.6 EAU80951.2 - 0.13 12.5 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase effector protein 4 DUF4596 PF15363.6 EAU80951.2 - 0.15 12.4 0.7 14 6.0 0.3 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) PD40 PF07676.12 EAU80951.2 - 0.15 12.1 0.0 29 4.8 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat B_solenoid_ydck PF18836.1 EAU80954.1 - 0.12 12.3 0.9 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Beta solenoid repeat from YDCK Pyr_redox_2 PF07992.14 EAU80955.2 - 5.7e-09 35.6 1.0 9.5e-07 28.3 0.8 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU80955.2 - 4.7e-06 26.7 0.3 7.4e-05 22.9 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU80955.2 - 4.8e-05 23.1 1.4 0.17 11.4 0.2 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAU80955.2 - 5.2e-05 22.6 0.0 1.9 7.7 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAU80955.2 - 6.1e-05 22.3 0.0 0.00052 19.3 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EAU80955.2 - 9e-05 22.5 2.8 2.4 8.1 0.0 4.5 4 0 0 4 4 4 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EAU80955.2 - 0.00016 20.5 2.3 0.47 9.1 0.1 3.6 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 EAU80955.2 - 0.00074 18.7 1.3 0.1 11.6 0.1 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 EAU80955.2 - 0.0017 18.7 0.0 2.8 8.4 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Amino_oxidase PF01593.24 EAU80955.2 - 0.0025 17.2 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EAU80955.2 - 0.019 15.5 1.8 3.1 8.4 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EAU80955.2 - 0.025 14.2 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 EAU80955.2 - 0.048 12.9 0.5 0.28 10.4 0.0 2.4 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 EAU80955.2 - 0.087 11.9 2.0 5 6.1 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EAU80955.2 - 0.11 12.6 0.0 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EAU80955.2 - 0.14 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DIOX_N PF14226.6 EAU80956.2 - 6.7e-26 91.4 0.0 1.1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAU80956.2 - 1.6e-18 67.0 0.0 3.5e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Hva1_TUDOR PF11160.8 EAU80958.2 - 0.0011 19.1 2.1 0.0031 17.6 2.1 1.8 1 1 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain PRONE PF03759.13 EAU80966.2 - 0.59 8.9 4.0 0.86 8.4 4.0 1.1 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) Lactamase_B_3 PF13483.6 EAU80968.1 - 1.7e-13 50.8 0.5 2.9e-12 46.8 0.5 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EAU80968.1 - 7.5e-13 48.4 2.3 4.5e-12 45.9 2.2 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAU80968.1 - 0.003 17.6 5.1 0.013 15.5 4.6 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily zf-MYND PF01753.18 EAU80969.2 - 1.1e-10 41.4 5.5 2.2e-10 40.5 5.5 1.5 1 0 0 1 1 1 1 MYND finger Inhibitor_I66 PF16850.5 EAU80970.1 - 1.3e-56 190.6 0.0 1.4e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 RicinB_lectin_2 PF14200.6 EAU80970.1 - 0.0094 16.7 0.0 0.85 10.4 0.0 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF4028 PF13220.6 EAU80970.1 - 0.056 13.2 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) zf-H2C2_5 PF13909.6 EAU80975.2 - 6.6e-19 67.3 22.1 0.001 18.8 0.6 7.6 7 0 0 7 7 7 5 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EAU80975.2 - 6.6e-08 32.6 57.8 0.00047 20.5 0.9 8.4 10 0 0 10 10 8 6 Zinc finger, C2H2 type FOXP-CC PF16159.5 EAU80975.2 - 1.8e-06 28.5 28.7 0.3 11.7 1.5 7.5 1 1 6 7 7 7 3 FOXP coiled-coil domain Ribosomal_L35p PF01632.19 EAU80975.2 - 0.00026 21.4 0.5 19 5.8 0.0 5.1 5 0 0 5 5 5 0 Ribosomal protein L35 OrsD PF12013.8 EAU80975.2 - 0.0018 18.7 26.2 5.4 7.5 0.8 7.8 7 2 2 9 9 9 3 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_6 PF13912.6 EAU80975.2 - 0.0048 16.9 0.1 0.017 15.1 0.1 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger PGM_PMM_II PF02879.16 EAU80975.2 - 0.015 15.9 0.0 40 4.9 0.0 4.3 3 2 1 4 4 4 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II zf-C2H2_4 PF13894.6 EAU80975.2 - 0.031 15.1 45.9 0.061 14.2 1.1 8.9 9 0 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU80975.2 - 0.2 12.0 0.2 0.2 12.0 0.2 3.2 4 0 0 4 4 2 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 EAU80975.2 - 0.5 10.1 0.0 0.5 10.1 0.0 5.7 3 2 3 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 EAU80975.2 - 0.82 10.1 11.6 0.82 10.2 0.4 4.1 4 0 0 4 4 3 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 EAU80975.2 - 3.2 6.8 4.7 8.7 5.4 4.7 1.8 1 1 0 1 1 1 0 Putative actin-like family SpdB PF05122.13 EAU80975.2 - 5 7.4 16.4 23 5.2 0.1 6.0 7 0 0 7 7 7 0 Mobile element transfer protein zf-H2C2_5 PF13909.6 EAU80976.2 - 8.5e-11 41.4 6.6 0.048 13.4 0.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EAU80976.2 - 5.9e-07 29.6 29.4 0.0019 18.5 2.0 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type FOXP-CC PF16159.5 EAU80976.2 - 0.00022 21.8 16.4 0.44 11.2 0.4 4.9 1 1 4 5 5 5 2 FOXP coiled-coil domain OrsD PF12013.8 EAU80976.2 - 0.00089 19.7 18.8 1.5 9.3 0.2 4.9 3 2 2 5 5 5 3 Orsellinic acid/F9775 biosynthesis cluster protein D Ribosomal_L35p PF01632.19 EAU80976.2 - 0.0015 19.0 1.7 0.51 10.9 0.0 3.0 3 1 0 3 3 3 2 Ribosomal protein L35 zf-H2C2_2 PF13465.6 EAU80976.2 - 0.023 15.1 28.4 0.028 14.9 2.4 5.7 6 0 0 6 6 6 0 Zinc-finger double domain Ntox5 PF15543.6 EAU80976.2 - 0.028 14.3 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial toxin 5 zf-C2H2_8 PF15909.5 EAU80976.2 - 0.056 13.7 13.5 0.28 11.5 3.8 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EAU80976.2 - 1.1 10.2 28.8 0.47 11.4 2.0 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger Megourin PF17560.2 EAU80976.2 - 1.6 9.1 7.9 1.5 9.1 0.5 3.2 4 0 0 4 4 4 0 Aphid Megourins His_Phos_1 PF00300.22 EAU80977.2 - 1.4e-10 41.2 0.2 1.1e-09 38.3 0.2 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phosducin PF02114.16 EAU80977.2 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosducin Inhibitor_I66 PF16850.5 EAU80979.1 - 1.1e-55 187.5 0.1 1.2e-55 187.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 zf-MYND PF01753.18 EAU80980.2 - 8.2e-10 38.6 6.6 2e-09 37.3 6.6 1.7 1 0 0 1 1 1 1 MYND finger SecY PF00344.20 EAU80981.2 - 2.2e-70 237.3 8.7 2.8e-70 237.0 8.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EAU80981.2 - 3.7e-19 68.3 0.1 2.2e-18 65.8 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p DUF4235 PF14019.6 EAU80981.2 - 0.2 11.8 0.9 12 6.0 0.6 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4235) Claudin_3 PF06653.11 EAU80981.2 - 0.95 9.4 0.0 0.95 9.4 0.0 3.1 3 1 1 4 4 4 0 Tight junction protein, Claudin-like DUF805 PF05656.14 EAU80981.2 - 4.7 7.7 6.5 1.2 9.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) ApoLp-III PF07464.11 EAU80982.1 - 0.027 14.6 0.4 0.04 14.0 0.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF5063 PF16702.5 EAU80982.1 - 0.067 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) COG2 PF06148.11 EAU80982.1 - 0.17 12.0 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1129 PF06570.11 EAU80984.2 - 0.27 10.7 0.1 0.27 10.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) AKAP7_NLS PF10469.9 EAU80986.2 - 4.2e-16 59.5 0.0 2.1e-14 53.9 0.0 2.7 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Ras PF00071.22 EAU80987.2 - 1.2e-25 90.1 0.0 1.2e-18 67.2 0.0 3.0 2 1 1 3 3 3 3 Ras family Roc PF08477.13 EAU80987.2 - 4.8e-09 36.5 0.0 4.8e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU80988.2 - 1.6e-20 73.3 0.0 7.1e-15 55.0 0.0 2.5 2 1 0 2 2 2 2 Ras family Roc PF08477.13 EAU80988.2 - 1.8e-12 47.5 0.0 2.1e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EAU80988.2 - 0.00047 20.1 0.1 0.0089 15.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EAU80988.2 - 0.013 16.0 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EAU80988.2 - 0.021 15.1 0.1 8.5 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAU80988.2 - 0.021 14.9 0.2 0.046 13.8 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 EAU80988.2 - 0.025 14.0 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_7 PF12775.7 EAU80988.2 - 0.049 13.1 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EAU80988.2 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Chor_lyase PF04345.13 EAU80988.2 - 0.15 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Chorismate lyase Gtr1_RagA PF04670.12 EAU80988.2 - 0.16 11.3 0.1 1.2 8.4 0.0 2.1 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Ras PF00071.22 EAU80990.2 - 2.2e-55 186.7 0.0 2.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU80990.2 - 9.1e-22 77.5 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU80990.2 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAU80990.2 - 0.0031 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAU80990.2 - 0.22 10.8 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 EAU80991.2 - 2.8e-18 66.0 0.0 6e-07 29.2 0.0 3.1 2 1 1 3 3 3 3 Ras family Roc PF08477.13 EAU80991.2 - 5.2e-09 36.4 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU80993.2 - 8.5e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Sugar_tr PF00083.24 EAU80994.2 - 1.4e-45 156.0 11.5 1.2e-25 90.3 0.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAU80994.2 - 6.2e-24 84.6 18.1 2e-15 56.6 0.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EAU80994.2 - 0.00037 18.9 0.5 0.0017 16.7 0.0 2.2 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 EAU80995.1 - 0.00021 21.1 0.7 0.00037 20.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU80995.1 - 0.0031 17.9 6.6 0.016 15.6 0.7 3.9 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF1996 PF09362.10 EAU80996.2 - 2.5e-65 220.8 0.0 3.3e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 EAU80997.2 - 8e-62 209.3 0.0 1.3e-61 208.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) GTP_CH_N PF12471.8 EAU81000.2 - 5.4e-91 303.6 0.0 7.5e-91 303.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EAU81000.2 - 5.8e-14 52.0 0.0 9.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II HTH_10 PF04967.12 EAU81000.2 - 0.088 12.6 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain GntR PF00392.21 EAU81000.2 - 0.13 11.9 0.1 40 4.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family BCA_ABC_TP_C PF12399.8 EAU81003.2 - 0.17 11.8 0.2 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter HsbA PF12296.8 EAU81004.1 - 0.051 14.0 1.1 0.16 12.4 0.9 1.9 1 1 1 2 2 2 0 Hydrophobic surface binding protein A ApoLp-III PF07464.11 EAU81004.1 - 0.18 11.9 0.4 0.25 11.4 0.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Ribonuclease_3 PF00636.26 EAU81005.1 - 4.5e-36 123.6 0.0 9.1e-17 61.6 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EAU81005.1 - 6.1e-22 77.6 0.1 2.1e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EAU81005.1 - 1.7e-20 73.5 0.0 1.2e-08 35.2 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.29 EAU81005.1 - 7.5e-16 58.4 0.0 1.4e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAU81005.1 - 1.4e-14 54.5 0.0 5.9e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAU81005.1 - 2.3e-14 53.6 0.0 5.1e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-MYND PF01753.18 EAU81006.2 - 1.2e-09 38.1 8.6 2.6e-09 37.0 8.6 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 EAU81007.2 - 5.8e-11 42.3 6.5 1.1e-10 41.4 6.5 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 EAU81007.2 - 0.037 15.2 0.1 0.072 14.3 0.1 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins LRRNT PF01462.18 EAU81007.2 - 0.34 10.6 2.3 3 7.6 0.8 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain H_lectin PF09458.10 EAU81009.1 - 1.7e-32 111.4 6.9 2.4e-14 53.2 0.2 3.4 3 0 0 3 3 3 3 H-type lectin domain NT-C2 PF10358.9 EAU81009.1 - 0.039 13.7 0.0 0.09 12.5 0.0 1.4 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins zf-MYND PF01753.18 EAU81010.1 - 1.2e-09 38.1 5.6 2e-09 37.3 5.6 1.4 1 0 0 1 1 1 1 MYND finger CENP-B_dimeris PF09026.10 EAU81012.2 - 0.06 13.7 3.8 0.075 13.4 0.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HBS1_N PF08938.10 EAU81012.2 - 0.23 11.8 4.1 0.5 10.7 4.1 1.5 1 0 0 1 1 1 0 HBS1 N-terminus zf-CCHC_6 PF15288.6 EAU81017.2 - 0.041 13.7 0.7 0.041 13.7 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EAU81017.2 - 0.19 11.6 13.0 2.5 8.0 2.7 3.1 2 1 0 2 2 2 0 Zinc knuckle Zn-ribbon_8 PF09723.10 EAU81017.2 - 0.2 11.8 3.5 1.6 9.0 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain YhfH PF14149.6 EAU81017.2 - 0.78 9.8 5.9 1.5 8.8 5.9 1.5 1 0 0 1 1 1 0 YhfH-like protein zf-C2H2_6 PF13912.6 EAU81017.2 - 0.8 9.8 6.5 4.6 7.4 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Desulfoferrod_N PF06397.12 EAU81017.2 - 0.93 9.2 4.5 2.3 7.9 0.4 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain HypA PF01155.19 EAU81017.2 - 0.93 9.5 3.1 1.4 8.9 3.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RPN6_N PF18055.1 EAU81018.2 - 3.4e-43 146.7 3.1 3.4e-43 146.7 3.1 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EAU81018.2 - 6.1e-17 62.0 0.0 1.8e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 EAU81018.2 - 4.9e-07 29.4 0.1 1.4e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EAU81018.2 - 0.001 19.3 14.7 1.2 9.5 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU81018.2 - 0.0019 18.1 6.5 0.13 12.4 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU81018.2 - 4 8.5 11.5 36 5.5 0.6 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat HNH_2 PF13391.6 EAU81019.1 - 0.00097 19.2 0.1 0.002 18.2 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Helitron_like_N PF14214.6 EAU81021.2 - 4.4e-23 82.5 0.0 5.7e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus KDZ PF18758.1 EAU81022.1 - 3e-18 66.3 0.0 4.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase RNR_Alpha PF17975.1 EAU81022.1 - 0.0066 16.9 0.3 0.027 15.0 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain F-box PF00646.33 EAU81025.2 - 3.4e-06 26.8 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain PSI_integrin PF17205.3 EAU81025.2 - 0.037 13.8 0.7 0.1 12.3 0.7 1.7 1 0 0 1 1 1 0 Integrin plexin domain F-box-like PF12937.7 EAU81025.2 - 0.053 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like DUF3701 PF12482.8 EAU81025.2 - 0.069 13.2 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Phage integrase protein Cyclin_N PF00134.23 EAU81026.2 - 6.4e-10 38.9 0.0 8.7e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Fungal_trans PF04082.18 EAU81027.2 - 5.1e-15 55.2 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GLTP PF08718.11 EAU81028.2 - 3.3e-35 121.5 0.0 4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pertussis_S1 PF02917.14 EAU81030.1 - 0.046 13.5 0.1 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Chs7 PF12271.8 EAU81033.2 - 5.2e-34 117.9 3.4 6.3e-34 117.7 3.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone BPD_transp_2 PF02653.16 EAU81033.2 - 0.025 13.8 0.5 0.025 13.8 0.5 1.9 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component DUF2070 PF09843.9 EAU81033.2 - 3.4 5.8 5.7 4.2 5.5 5.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) NfeD PF01957.18 EAU81040.2 - 0.037 14.4 0.0 0.087 13.2 0.0 1.6 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Cyt-b5 PF00173.28 EAU81041.1 - 1.6e-11 44.2 0.1 2.1e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Serglycin PF04360.12 EAU81042.1 - 0.13 12.2 3.1 0.17 11.8 3.1 1.3 1 0 0 1 1 1 0 Serglycin Herpes_capsid PF06112.11 EAU81042.1 - 1.8 8.6 10.9 2.4 8.2 10.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DJ-1_PfpI PF01965.24 EAU81043.1 - 9.3e-14 51.6 0.0 1.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EAU81043.1 - 9.4e-12 45.0 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like zf-MYND PF01753.18 EAU81044.2 - 1.9e-10 40.7 6.1 1.9e-10 40.7 6.1 2.2 2 0 0 2 2 2 1 MYND finger Meleagrin PF08189.11 EAU81044.2 - 0.12 12.0 1.0 0.32 10.7 1.0 1.6 1 0 0 1 1 1 0 Meleagrin/Cygnin family ATG7_N PF16420.5 EAU81046.2 - 7.2e-88 295.1 0.0 1e-87 294.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EAU81046.2 - 1.9e-37 128.9 0.0 2.7e-36 125.2 0.0 2.3 2 1 1 3 3 3 1 ThiF family Shikimate_DH PF01488.20 EAU81046.2 - 0.031 14.3 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FCD PF07729.12 EAU81048.1 - 0.0018 18.7 0.9 0.0067 16.8 0.3 2.0 2 0 0 2 2 2 1 FCD domain IML1 PF12257.8 EAU81048.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 BDHCT_assoc PF16204.5 EAU81049.2 - 0.15 11.7 2.1 0.21 11.3 2.1 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein Flg_hook PF02120.16 EAU81049.2 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Sugar_tr PF00083.24 EAU81051.1 - 4.6e-35 121.3 19.0 7.4e-35 120.7 19.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU81051.1 - 4.7e-35 121.2 27.9 4.7e-35 121.2 27.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily RPN7 PF10602.9 EAU81052.1 - 3.7e-56 189.6 0.5 5.3e-56 189.1 0.5 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EAU81052.1 - 7.3e-16 58.6 0.0 3.1e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain SR-25 PF10500.9 EAU81052.1 - 0.12 12.0 0.6 0.18 11.4 0.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_2 PF07719.17 EAU81052.1 - 0.2 11.8 4.9 1.6 9.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sharpin_PH PF16764.5 EAU81053.2 - 0.089 12.6 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Sharpin PH domain DUF1652 PF07865.11 EAU81054.2 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) DUF3327 PF11806.8 EAU81056.2 - 0.037 14.7 0.1 0.21 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3327) Pkinase_fungal PF17667.1 EAU81059.1 - 2.8e-42 144.9 0.0 3.6e-22 78.7 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EAU81059.1 - 0.14 12.1 0.0 0.5 10.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF594 PF04578.13 EAU81060.2 - 0.054 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF594 LBP_BPI_CETP PF01273.25 EAU81061.1 - 0.032 13.8 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain F-box-like PF12937.7 EAU81061.1 - 0.073 13.0 0.4 0.55 10.2 0.1 2.6 2 0 0 2 2 2 0 F-box-like Glyoxal_oxid_N PF07250.11 EAU81062.2 - 1.1e-37 129.6 0.0 7e-30 104.0 0.0 3.2 3 0 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EAU81062.2 - 2.9e-23 82.0 0.0 6.4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 EAU81062.2 - 0.011 15.7 0.1 6.9 6.8 0.0 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain LAM_C PF12544.8 EAU81064.1 - 0.54 10.4 2.5 0.55 10.4 0.1 2.0 1 1 1 2 2 2 0 Lysine-2,3-aminomutase Epimerase PF01370.21 EAU81065.2 - 6.3e-06 25.8 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAU81065.2 - 4.1e-05 23.6 0.0 0.00052 19.9 0.0 2.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAU81065.2 - 0.00015 21.4 0.3 0.00028 20.5 0.3 1.6 1 1 0 1 1 1 1 NmrA-like family Sortilin-Vps10 PF15902.5 EAU81066.2 - 2e-300 995.9 0.6 1.9e-151 504.9 0.1 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EAU81066.2 - 7.1e-96 319.4 12.8 7.2e-52 176.1 3.4 2.6 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EAU81066.2 - 4.6e-13 47.0 29.2 1 9.7 0.1 11.3 10 0 0 10 10 10 5 BNR/Asp-box repeat BNR_2 PF13088.6 EAU81066.2 - 0.00024 20.5 6.0 3.4 6.9 0.0 5.3 5 2 0 5 5 5 2 BNR repeat-like domain PSII_BNR PF14870.6 EAU81066.2 - 0.0011 18.3 2.2 4 6.6 0.0 4.5 4 1 1 5 5 5 2 Photosynthesis system II assembly factor YCF48 F5_F8_type_C PF00754.25 EAU81066.2 - 0.0015 18.6 6.3 2.6 8.2 0.0 6.5 8 1 0 8 8 8 1 F5/8 type C domain CHB_HEX_C PF03174.13 EAU81066.2 - 0.02 14.9 7.5 16 5.5 0.0 5.8 7 1 1 8 8 8 0 Chitobiase/beta-hexosaminidase C-terminal domain DR2241 PF18069.1 EAU81066.2 - 0.043 13.7 0.2 0.16 11.8 0.1 2.1 2 0 0 2 2 2 0 DR2241 stabilising domain Fe_dep_repr_C PF02742.15 EAU81066.2 - 0.15 12.1 0.0 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain DUF1860 PF08949.10 EAU81066.2 - 0.31 10.7 1.9 1.8 8.3 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) BNR_6 PF15899.5 EAU81066.2 - 0.51 10.5 7.5 9.9 6.5 0.1 4.4 4 0 0 4 4 4 0 BNR-Asp box repeat Pkinase_fungal PF17667.1 EAU81067.1 - 4.5e-30 104.8 0.0 7.1e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 EAU81068.2 - 3.2e-56 190.9 0.0 4.6e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU81068.2 - 0.00036 20.5 0.0 0.013 15.5 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EAU81068.2 - 0.0034 16.8 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU81069.2 - 1e-05 24.5 0.1 1.7e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase DUF155 PF02582.14 EAU81069.2 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 ImpA_N PF06812.12 EAU81069.2 - 0.25 11.5 0.9 2.8 8.1 0.0 2.6 2 1 1 3 3 3 0 ImpA, N-terminal, type VI secretion system Pkinase_fungal PF17667.1 EAU81070.1 - 6.5e-70 236.0 3.5 2.2e-37 128.8 0.1 3.4 3 1 1 4 4 4 3 Fungal protein kinase APH PF01636.23 EAU81070.1 - 0.0039 17.2 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EAU81070.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 EAU81070.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-MYND PF01753.18 EAU81072.2 - 4.1e-08 33.2 9.4 8.3e-08 32.2 9.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C2H2_assoc PF16606.5 EAU81074.2 - 0.0034 17.6 0.8 0.036 14.3 0.4 2.3 2 0 0 2 2 2 1 Unstructured conserved, between two C2H2-type zinc-fingers MMPL PF03176.15 EAU81074.2 - 1.1 8.1 2.9 0.68 8.8 1.3 1.4 2 0 0 2 2 2 0 MMPL family Asp PF00026.23 EAU81075.2 - 1.9e-07 30.8 0.0 9.3e-05 22.0 0.0 3.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Cellulase PF00150.18 EAU81078.2 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pheromone PF08015.11 EAU81081.1 - 1.6 9.8 4.5 5.5 8.1 0.4 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone RAG1 PF12940.7 EAU81083.2 - 0.13 10.3 0.4 8.2 4.4 0.4 2.1 2 0 0 2 2 2 0 Recombination-activation protein 1 (RAG1), recombinase zf-MYST PF17772.1 EAU81083.2 - 1.1 8.9 2.9 0.84 9.3 0.3 2.0 2 0 0 2 2 2 0 MYST family zinc finger domain Antimicrobial10 PF08105.11 EAU81084.2 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Metchnikowin family KASH_CCD PF14662.6 EAU81085.1 - 3.5e-05 23.7 2.2 6.8e-05 22.8 2.2 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH KELK PF15796.5 EAU81085.1 - 0.00032 21.1 1.3 0.0008 19.8 1.3 1.7 1 0 0 1 1 1 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase CdvA PF18822.1 EAU81085.1 - 0.00051 19.9 1.7 0.66 9.8 0.1 2.3 2 0 0 2 2 2 2 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 EAU81085.1 - 0.00052 19.9 3.8 0.0024 17.8 1.5 2.2 2 0 0 2 2 2 1 Prefoldin subunit FlaC_arch PF05377.11 EAU81085.1 - 0.00075 19.8 3.4 0.0046 17.3 1.7 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) ERM PF00769.19 EAU81085.1 - 0.0012 18.7 1.7 0.0016 18.3 1.7 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family ZapB PF06005.12 EAU81085.1 - 0.0024 18.3 3.1 0.08 13.4 2.4 2.4 2 0 0 2 2 2 1 Cell division protein ZapB DUF4988 PF16378.5 EAU81085.1 - 0.004 16.8 0.1 0.79 9.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function Cep57_MT_bd PF06657.13 EAU81085.1 - 0.0047 17.3 2.2 0.0085 16.5 0.5 2.4 2 1 0 2 2 1 1 Centrosome microtubule-binding domain of Cep57 Med21 PF11221.8 EAU81085.1 - 0.005 17.1 1.7 0.005 17.1 1.7 1.8 2 0 0 2 2 1 1 Subunit 21 of Mediator complex YabA PF06156.13 EAU81085.1 - 0.0052 17.4 3.3 0.057 14.1 3.3 2.3 1 1 0 1 1 1 1 Initiation control protein YabA AKNA PF12443.8 EAU81085.1 - 0.0061 17.2 0.5 0.76 10.5 0.1 2.6 2 0 0 2 2 2 1 AT-hook-containing transcription factor MAD PF05557.13 EAU81085.1 - 0.0068 14.8 2.0 0.011 14.2 2.0 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.18 EAU81085.1 - 0.0089 16.3 10.5 0.08 13.3 4.4 3.2 3 0 0 3 3 3 1 TSC-22/dip/bun family DUF16 PF01519.16 EAU81085.1 - 0.011 16.2 0.1 0.02 15.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Cnn_1N PF07989.11 EAU81085.1 - 0.012 15.8 1.8 0.12 12.6 0.6 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 EAU81085.1 - 0.012 15.7 9.9 0.054 13.6 4.5 2.8 3 0 0 3 3 2 0 bZIP transcription factor DUF4140 PF13600.6 EAU81085.1 - 0.012 16.0 0.4 0.069 13.6 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.22 EAU81085.1 - 0.012 15.8 2.7 0.16 12.2 3.1 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 EAU81085.1 - 0.012 15.8 2.6 0.021 15.0 2.6 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIVA PF05103.13 EAU81085.1 - 0.016 15.3 1.9 1.5 8.9 1.2 2.3 2 0 0 2 2 2 0 DivIVA protein Syntaxin-6_N PF09177.11 EAU81085.1 - 0.018 15.5 0.3 0.056 14.0 0.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 EAU81085.1 - 0.019 14.3 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 EAU81085.1 - 0.02 14.9 7.6 0.28 11.2 7.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 EAU81085.1 - 0.021 14.9 0.4 0.04 14.0 0.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 EAU81085.1 - 0.022 14.0 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein GIT_CC PF16559.5 EAU81085.1 - 0.022 14.6 0.1 0.82 9.6 0.0 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Mod_r PF07200.13 EAU81085.1 - 0.027 14.6 0.1 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CC2-LZ PF16516.5 EAU81085.1 - 0.037 14.4 6.0 0.19 12.1 1.6 2.3 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CASP_C PF08172.12 EAU81085.1 - 0.042 13.2 0.3 0.064 12.6 0.3 1.5 1 0 0 1 1 1 0 CASP C terminal Macoilin PF09726.9 EAU81085.1 - 0.044 12.4 0.4 0.063 11.8 0.4 1.2 1 0 0 1 1 1 0 Macoilin family DUF1664 PF07889.12 EAU81085.1 - 0.044 13.8 0.7 0.15 12.1 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG17 PF04108.12 EAU81085.1 - 0.047 12.8 0.3 0.068 12.3 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 ORF6C PF10552.9 EAU81085.1 - 0.048 13.7 2.3 0.051 13.7 0.6 1.8 2 0 0 2 2 1 0 ORF6C domain DUF3450 PF11932.8 EAU81085.1 - 0.05 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FliT PF05400.13 EAU81085.1 - 0.057 14.2 2.5 5.1 8.0 0.6 2.6 2 0 0 2 2 2 0 Flagellar protein FliT GCN5L1 PF06320.13 EAU81085.1 - 0.068 13.3 0.2 0.19 11.9 0.1 1.9 2 1 0 2 2 1 0 GCN5-like protein 1 (GCN5L1) DUF812 PF05667.11 EAU81085.1 - 0.071 12.0 3.9 0.17 10.7 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Snapin_Pallidin PF14712.6 EAU81085.1 - 0.075 13.5 0.3 0.22 12.0 0.3 1.8 1 1 0 1 1 1 0 Snapin/Pallidin SHE3 PF17078.5 EAU81085.1 - 0.1 12.3 1.4 0.17 11.6 0.4 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4200 PF13863.6 EAU81085.1 - 0.11 12.9 4.7 0.45 10.9 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) MCU PF04678.13 EAU81085.1 - 0.11 12.5 1.0 0.14 12.3 0.3 1.6 2 0 0 2 2 1 0 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 EAU81085.1 - 0.12 11.9 1.7 0.19 11.3 0.6 1.8 1 1 1 2 2 2 0 fzo-like conserved region LMBR1 PF04791.16 EAU81085.1 - 0.14 11.1 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1515 PF07439.11 EAU81085.1 - 0.15 12.1 1.3 0.3 11.1 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TACC_C PF05010.14 EAU81085.1 - 0.15 11.8 6.1 1.2 8.9 2.7 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal V_ATPase_I PF01496.19 EAU81085.1 - 0.16 9.9 0.1 0.18 9.7 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EzrA PF06160.12 EAU81085.1 - 0.18 9.9 1.3 0.48 8.5 1.4 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.6 EAU81085.1 - 0.19 11.0 5.4 0.72 9.2 5.4 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC-167 PF15188.6 EAU81085.1 - 0.21 11.9 9.1 0.85 10.0 3.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Tropomyosin_1 PF12718.7 EAU81085.1 - 0.23 11.6 9.4 0.62 10.2 6.8 2.5 2 1 0 2 2 2 0 Tropomyosin like DUF4446 PF14584.6 EAU81085.1 - 0.23 11.4 2.5 0.36 10.8 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DivIC PF04977.15 EAU81085.1 - 0.25 11.2 2.9 0.36 10.6 2.3 1.7 1 1 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.6 EAU81085.1 - 0.26 9.9 1.4 0.46 9.1 1.3 1.5 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.11 EAU81085.1 - 0.3 9.9 4.9 0.66 8.8 4.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 EAU81085.1 - 0.37 11.1 2.6 8.2 6.8 0.3 2.6 2 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uds1 PF15456.6 EAU81085.1 - 0.38 10.9 4.7 13 5.9 0.0 2.4 2 1 0 2 2 2 0 Up-regulated During Septation Phage_GP20 PF06810.11 EAU81085.1 - 0.38 10.5 1.8 2.3 8.0 1.9 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 HOOK PF05622.12 EAU81085.1 - 0.48 8.5 7.3 0.37 8.9 5.6 1.4 1 1 0 1 1 1 0 HOOK protein SKA2 PF16740.5 EAU81085.1 - 0.76 9.6 5.2 2 8.3 1.1 2.5 2 1 1 3 3 2 0 Spindle and kinetochore-associated protein 2 TMF_TATA_bd PF12325.8 EAU81085.1 - 1.3 9.3 8.7 7.7 6.8 8.7 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.19 EAU81085.1 - 1.5 8.4 6.5 7.1 6.3 6.5 2.0 1 1 0 1 1 1 0 GrpE Spc24 PF08286.11 EAU81085.1 - 1.6 9.0 4.7 16 5.8 4.7 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Troponin PF00992.20 EAU81085.1 - 3 8.1 9.9 0.88 9.9 5.8 2.1 1 1 1 2 2 2 0 Troponin TPR_MLP1_2 PF07926.12 EAU81085.1 - 3.2 7.8 7.3 6.4 6.9 4.1 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 EAU81085.1 - 4.5 7.4 10.3 0.67 10.1 4.8 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Tnp_22_trimer PF17489.2 EAU81085.1 - 5.2 7.1 12.7 0.66 10.0 1.0 2.8 2 1 0 2 2 2 0 L1 transposable element trimerization domain DUF1394 PF07159.12 EAU81092.1 - 0.008 15.5 0.0 0.0089 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Ntox28 PF15605.6 EAU81092.1 - 0.045 14.0 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 Bacterial toxin 28 LMBR1 PF04791.16 EAU81092.1 - 0.22 10.4 0.2 0.25 10.2 0.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein YqaJ PF09588.10 EAU81096.2 - 0.093 12.9 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain KDZ PF18758.1 EAU81104.2 - 3.3e-28 98.8 0.2 4.3e-25 88.6 0.1 2.4 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU81104.2 - 5.4e-22 78.0 0.2 1.8e-21 76.3 0.2 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU81104.2 - 0.0038 17.4 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU81104.2 - 0.035 13.9 0.0 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases HMG_box_2 PF09011.10 EAU81105.1 - 1.1e-05 25.9 0.1 5.3e-05 23.7 0.1 2.1 1 0 0 1 1 1 1 HMG-box domain DUF5644 PF18712.1 EAU81106.1 - 0.2 11.7 0.1 0.38 10.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5644) Csm1_N PF18504.1 EAU81106.1 - 0.62 10.4 4.9 1.6 9.1 1.9 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain DASH_Spc34 PF08657.10 EAU81106.1 - 7.4 6.3 11.8 0.052 13.3 3.4 1.7 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF745 PF05335.13 EAU81108.1 - 0.017 14.8 0.2 0.025 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ZYG-11_interact PF05884.12 EAU81108.1 - 0.025 14.0 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 THOC7 PF05615.13 EAU81108.1 - 0.082 13.2 0.6 0.11 12.7 0.6 1.4 1 1 0 1 1 1 0 Tho complex subunit 7 BLOC1_2 PF10046.9 EAU81108.1 - 0.11 12.8 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SH2_2 PF14633.6 EAU81111.2 - 1.8e-35 122.3 0.5 2.7e-35 121.8 0.5 1.2 1 0 0 1 1 1 1 SH2 domain S1 PF00575.23 EAU81111.2 - 8.2e-07 29.3 0.7 1.7e-06 28.3 0.6 1.6 1 1 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 EAU81111.2 - 0.00027 21.0 0.0 0.00077 19.5 0.0 1.7 2 0 0 2 2 2 1 SH2 domain DUF2110 PF09883.9 EAU81111.2 - 0.018 14.6 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) Arrestin_N PF00339.29 EAU81111.2 - 0.032 14.3 0.4 0.051 13.6 0.4 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain SH2_2 PF14633.6 EAU81112.2 - 6.6e-23 81.3 0.2 8.7e-22 77.6 0.2 2.0 1 1 0 1 1 1 1 SH2 domain Apolipoprotein PF01442.18 EAU81113.2 - 0.0032 17.4 13.9 0.0032 17.4 13.9 2.3 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain HIP1_clath_bdg PF16515.5 EAU81113.2 - 0.042 14.5 21.7 2 9.1 5.2 3.3 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Rab5-bind PF09311.11 EAU81113.2 - 0.094 12.1 16.3 0.11 11.9 15.3 1.5 1 1 0 1 1 1 0 Rabaptin-like protein ApoLp-III PF07464.11 EAU81113.2 - 0.096 12.8 7.2 0.43 10.7 3.6 2.7 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 EAU81113.2 - 0.097 13.1 0.4 0.097 13.1 0.4 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EAU81113.2 - 0.25 11.4 2.8 0.32 11.0 0.5 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 EAU81113.2 - 0.29 9.2 11.3 0.091 10.9 7.7 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Syntaxin-6_N PF09177.11 EAU81113.2 - 0.47 11.0 12.9 2.8 8.5 2.7 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PXA PF02194.15 EAU81113.2 - 0.78 9.7 12.3 1.1 9.2 8.6 2.2 1 1 1 2 2 2 0 PXA domain Prominin PF05478.11 EAU81113.2 - 0.88 7.4 10.1 1.7 6.5 10.1 1.4 1 1 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.12 EAU81113.2 - 1.4 9.0 21.9 0.13 12.4 13.8 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EAU81113.2 - 1.7 8.7 11.9 1.3 9.0 3.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Lectin_N PF03954.14 EAU81113.2 - 1.8 8.3 6.5 0.17 11.6 1.2 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 EAU81113.2 - 2.2 8.4 13.9 21 5.3 8.4 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 EAU81113.2 - 3.5 7.4 12.5 0.97 9.2 7.8 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 Laminin_I PF06008.14 EAU81113.2 - 4 7.1 16.9 0.7 9.5 12.4 1.9 2 1 0 2 2 2 0 Laminin Domain I ERM PF00769.19 EAU81113.2 - 4.4 7.0 20.1 4.5 7.0 9.0 2.3 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Spore_III_AB PF09548.10 EAU81113.2 - 5.3 7.1 7.9 11 6.1 7.9 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) GAS PF13851.6 EAU81113.2 - 5.3 6.3 24.0 1.1 8.5 5.2 2.6 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 EAU81113.2 - 6.6 6.8 21.0 0.032 14.4 5.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus IFT57 PF10498.9 EAU81113.2 - 7 5.5 16.6 34 3.3 16.6 2.1 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 KxDL PF10241.9 EAU81113.2 - 7.8 6.8 12.9 0.69 10.2 1.8 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.6 EAU81113.2 - 9.1 5.5 9.8 43 3.3 9.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 EAU81113.2 - 9.8 6.2 17.4 0.27 11.2 4.0 3.3 3 1 1 4 4 4 0 Prefoldin subunit Sad1_UNC PF07738.13 EAU81114.2 - 2.4e-10 40.5 0.0 8.9e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal zf-C3HC4 PF00097.25 EAU81115.2 - 0.003 17.4 6.9 0.003 17.4 6.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU81115.2 - 0.014 15.6 5.9 0.044 13.9 5.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAU81115.2 - 0.015 15.4 4.7 0.015 15.4 4.7 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAU81115.2 - 0.08 12.8 11.6 0.059 13.2 4.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-FCS PF06467.14 EAU81115.2 - 0.091 12.7 0.1 0.091 12.7 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-RING_2 PF13639.6 EAU81115.2 - 0.34 11.3 9.1 0.18 12.1 5.4 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 EAU81115.2 - 0.47 10.3 11.9 0.099 12.5 7.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU81115.2 - 6.6 6.8 13.4 2.9 7.9 9.3 2.4 2 1 1 3 3 3 0 zinc-RING finger domain PKD PF00801.20 EAU81116.2 - 0.019 14.8 1.4 0.075 12.9 1.0 2.1 2 0 0 2 2 2 0 PKD domain DUF2502 PF10697.9 EAU81116.2 - 0.72 10.2 4.2 0.21 12.0 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) NPL PF17800.1 EAU81117.1 - 0.00038 21.0 0.0 0.00076 20.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin-like domain F-box-like PF12937.7 EAU81119.2 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like Blt1_C PF17183.4 EAU81119.2 - 0.14 11.8 0.0 0.95 9.1 0.0 2.1 2 0 0 2 2 2 0 Get5 carboxyl domain F-box-like PF12937.7 EAU81120.1 - 0.00023 21.0 0.2 0.00023 21.0 0.2 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EAU81120.1 - 0.0084 16.0 0.1 0.036 14.0 0.1 2.1 1 1 0 1 1 1 1 F-box domain NPL PF17800.1 EAU81121.1 - 0.021 15.4 0.0 0.052 14.1 0.0 1.7 2 0 0 2 2 2 0 Nucleoplasmin-like domain RAB3GAP2_N PF14655.6 EAU81122.2 - 0.00027 20.4 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 EAU81122.2 - 0.0004 21.1 7.1 0.27 12.2 0.0 4.8 6 0 0 6 6 6 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EAU81122.2 - 0.0065 15.3 0.1 0.0097 14.7 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Ras PF00071.22 EAU81123.2 - 4.3e-14 52.4 0.3 5.6e-07 29.3 0.0 2.1 1 1 1 2 2 2 2 Ras family Transposase_21 PF02992.14 EAU81124.2 - 4.2e-16 58.8 0.0 8e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 EAU81124.2 - 2.2e-06 27.3 0.3 4.9e-06 26.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SAP PF02037.27 EAU81124.2 - 0.042 13.6 0.2 0.2 11.5 0.2 2.3 1 1 0 1 1 1 0 SAP domain Plavaka PF18759.1 EAU81124.2 - 0.059 12.6 0.8 0.14 11.3 0.2 1.8 2 0 0 2 2 2 0 Plavaka transposase zf-MYND PF01753.18 EAU81127.2 - 9e-08 32.1 5.4 1.8e-07 31.2 5.4 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 EAU81127.2 - 0.0064 17.7 3.0 0.015 16.5 3.0 1.6 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins TetR_C_32 PF09209.11 EAU81127.2 - 0.036 14.0 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CDC45 PF02724.14 EAU81127.2 - 0.066 11.5 5.6 0.092 11.0 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EAU81127.2 - 0.48 9.8 14.8 0.77 9.1 14.8 1.3 1 0 0 1 1 1 0 SDA1 GMC_oxred_N PF00732.19 EAU81128.2 - 1.4e-50 172.3 0.0 2.3e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU81128.2 - 1.3e-28 100.3 0.0 3.2e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU81128.2 - 0.00025 21.2 0.5 0.0007 19.8 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU81128.2 - 0.00057 19.1 0.0 0.00085 18.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAU81128.2 - 0.0023 17.1 0.7 0.0038 16.4 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAU81128.2 - 0.0047 16.6 0.4 0.0099 15.5 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EAU81128.2 - 0.03 13.6 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EAU81128.2 - 0.034 13.4 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_oprn_chp PF09534.10 EAU81128.2 - 0.041 13.7 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Pkinase_fungal PF17667.1 EAU81129.1 - 7e-08 31.7 0.0 1.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Fis1_TPR_C PF14853.6 EAU81129.1 - 0.09 12.9 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat PRANC PF09372.10 EAU81136.1 - 0.0051 17.1 0.8 0.013 15.8 0.1 2.0 2 0 0 2 2 2 1 PRANC domain LRR_8 PF13855.6 EAU81139.2 - 0.013 15.2 2.0 1.5 8.6 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat LBP_C PF17386.2 EAU81141.1 - 0.13 12.1 0.1 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Lacto-N-biose phosphorylase C-terminal domain p450 PF00067.22 EAU81142.1 - 2.8e-29 102.2 0.0 1.3e-28 100.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.27 EAU81143.2 - 3.5e-53 177.5 1.8 2.2e-22 78.8 0.4 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SWI2_SNF2 PF18766.1 EAU81143.2 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase FtsJ PF01728.19 EAU81144.1 - 8.6e-41 140.0 0.0 1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Y_phosphatase2 PF03162.13 EAU81145.2 - 0.15 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Kelch_6 PF13964.6 EAU81146.1 - 2.1e-13 50.0 11.0 8.2e-09 35.4 0.1 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 EAU81146.1 - 3.6e-09 36.7 1.5 0.0031 17.7 0.0 5.7 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EAU81146.1 - 3.7e-09 36.4 0.1 0.062 13.3 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EAU81146.1 - 9e-09 34.8 5.9 0.097 12.3 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 EAU81146.1 - 1.2e-07 31.6 15.3 0.63 10.1 0.1 7.4 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EAU81146.1 - 4.4e-07 29.6 10.7 0.23 11.5 0.1 6.0 6 0 0 6 6 6 1 Kelch motif zf-C6H2 PF15801.5 EAU81146.1 - 0.0012 19.1 6.8 0.0032 17.7 6.8 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EAU81146.1 - 0.0048 17.0 4.7 0.011 15.8 4.7 1.6 1 0 0 1 1 1 1 MYND finger PPR PF01535.20 EAU81146.1 - 0.058 13.7 0.3 0.058 13.7 0.3 3.6 5 0 0 5 5 5 0 PPR repeat PPR_2 PF13041.6 EAU81146.1 - 0.68 10.2 5.1 0.37 11.0 0.1 2.9 3 0 0 3 3 3 0 PPR repeat family DUF1996 PF09362.10 EAU81147.2 - 3.4e-66 223.6 7.0 3.7e-66 223.5 3.7 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU81147.2 - 9.8e-12 44.6 12.3 9.8e-12 44.6 12.3 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAU81147.2 - 0.032 14.5 0.4 0.075 13.3 0.4 1.6 1 0 0 1 1 1 0 Toxin 7 zf-TFIIIC PF12660.7 EAU81148.2 - 0.045 13.7 0.1 0.078 12.9 0.1 1.5 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex RNA_pol_Rbc25 PF08292.12 EAU81149.1 - 5.1e-33 114.1 0.1 9.8e-33 113.1 0.1 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EAU81149.1 - 1.5e-22 79.7 0.0 2.9e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase_fungal PF17667.1 EAU81150.2 - 5.3e-64 216.5 0.0 1e-31 110.2 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EAU81150.2 - 0.055 13.4 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAU81150.2 - 0.068 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 EAU81150.2 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 EAU81151.1 - 6.3e-38 130.6 0.0 1.7e-32 112.7 0.0 2.7 2 1 1 3 3 3 2 Fungal protein kinase Pkinase_fungal PF17667.1 EAU81152.1 - 5.2e-37 127.6 0.2 2.7e-26 92.3 0.0 2.6 2 1 1 3 3 3 2 Fungal protein kinase PMI_typeI PF01238.21 EAU81153.1 - 7e-119 397.3 0.0 8.2e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EAU81153.1 - 0.0067 16.1 0.1 3.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EAU81153.1 - 0.0072 16.2 0.0 6.3 6.7 0.0 3.0 3 0 0 3 3 3 2 AraC-like ligand binding domain Aminotran_5 PF00266.19 EAU81154.1 - 2.1e-18 66.5 0.0 3.6e-18 65.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EAU81154.1 - 2.7e-06 26.8 0.0 4.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EAU81154.1 - 8.2e-06 25.4 0.0 0.039 13.3 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EAU81154.1 - 0.16 10.6 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF368 PF04018.13 EAU81155.2 - 0.11 12.0 6.1 0.048 13.2 1.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF368) Pkinase_fungal PF17667.1 EAU81156.1 - 7e-43 146.9 0.0 7e-22 77.8 0.0 2.2 1 1 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EAU81156.1 - 0.00086 19.3 0.0 0.3 10.9 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family GMC_oxred_N PF00732.19 EAU81159.1 - 2.1e-56 191.5 0.0 3.1e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU81159.1 - 2.8e-34 118.7 0.0 5.3e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAU81159.1 - 0.00016 20.9 1.2 0.059 12.4 1.8 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EAU81159.1 - 0.0041 17.3 0.3 0.013 15.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU81159.1 - 0.022 14.3 0.8 0.28 10.7 1.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAU81159.1 - 0.044 13.0 0.1 0.49 9.6 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EAU81159.1 - 0.048 12.9 0.3 1.1 8.5 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU81159.1 - 0.083 12.1 0.0 0.63 9.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU81159.1 - 0.17 10.9 0.7 0.27 10.3 0.7 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fungal_trans PF04082.18 EAU81161.2 - 7.6e-22 77.6 0.0 1.8e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain SapB_2 PF03489.17 EAU81162.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Saposin-like type B, region 2 Tet_JBP PF12851.7 EAU81164.2 - 6e-09 35.7 0.0 8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy PF03171.20 EAU81164.2 - 0.0024 18.3 0.0 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily KDZ PF18758.1 EAU81166.2 - 1.1e-42 146.2 0.1 2.2e-42 145.2 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU81166.2 - 4.2e-25 88.0 0.1 5.8e-22 77.9 0.1 2.5 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases CCDC71L PF15374.6 EAU81166.2 - 0.026 13.8 2.1 0.059 12.6 2.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L CxC3 PF18804.1 EAU81166.2 - 0.074 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases HMG_box_2 PF09011.10 EAU81167.2 - 0.19 12.4 2.1 0.95 10.1 2.1 2.2 1 1 1 2 2 2 0 HMG-box domain EzrA PF06160.12 EAU81168.1 - 0.0043 15.3 0.5 0.0068 14.6 0.5 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF1664 PF07889.12 EAU81168.1 - 0.069 13.2 6.5 0.33 11.0 3.1 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EAU81168.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 EAU81168.1 - 1.6 9.2 4.4 2.4 8.7 1.4 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EAU81168.1 - 1.8 8.6 6.2 1.8 8.5 1.5 2.9 2 2 0 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 EAU81168.1 - 4.1 7.5 8.4 0.089 12.9 0.4 2.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein zf-MYND PF01753.18 EAU81170.1 - 0.00036 20.6 11.1 0.00081 19.4 11.1 1.6 1 0 0 1 1 1 1 MYND finger zf-Tim10_DDP PF02953.15 EAU81182.2 - 1.6e-13 50.1 2.0 1.4e-11 43.9 2.0 2.1 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Fer4_12 PF13353.6 EAU81182.2 - 0.053 13.8 0.1 0.056 13.7 0.1 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain Molybdopterin PF00384.22 EAU81183.2 - 7.9e-68 229.4 0.0 4e-67 227.1 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EAU81183.2 - 1.2e-20 73.4 0.3 4e-20 71.7 0.3 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EAU81183.2 - 2.7e-17 62.0 0.2 2.7e-17 62.0 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 EAU81183.2 - 9.6e-16 58.2 0.0 2.4e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 EAU81183.2 - 8.7e-09 35.2 0.7 8.7e-09 35.2 0.7 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EAU81183.2 - 0.0083 15.9 0.1 0.25 11.1 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 EAU81183.2 - 0.1 12.5 1.1 4.9 7.1 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Cut8 PF08559.10 EAU81187.1 - 0.11 12.1 0.5 0.19 11.3 0.5 1.3 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein VLPT PF07122.11 EAU81187.1 - 3.1 7.6 8.2 5.5 6.8 0.0 3.3 3 0 0 3 3 3 0 Variable length PCR target protein (VLPT) Chitin_synth_2 PF03142.15 EAU81188.2 - 9.6e-238 790.0 0.0 1.3e-237 789.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EAU81188.2 - 6e-121 404.8 0.0 3.1e-108 362.8 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 EAU81188.2 - 5e-19 68.0 0.2 1.6e-18 66.4 0.4 1.8 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EAU81188.2 - 4.4e-12 46.0 0.1 9.1e-07 28.9 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EAU81188.2 - 3.7e-09 36.8 3.6 9.2e-09 35.5 3.6 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAU81188.2 - 1.3e-08 35.1 0.0 2.2e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EAU81188.2 - 0.011 15.5 0.0 4 7.2 0.0 2.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 PTPA PF03095.15 EAU81189.2 - 3.2e-129 430.7 0.0 3.9e-129 430.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein SURF6 PF04935.12 EAU81190.1 - 1.1e-45 156.0 44.6 1.1e-45 156.0 44.6 2.6 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EAU81190.1 - 2.1e-17 63.4 4.1 2.1e-17 63.4 4.1 5.6 4 1 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 RR_TM4-6 PF06459.12 EAU81192.2 - 1.2 8.9 14.4 1.5 8.5 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 EAU81192.2 - 2.2 7.8 9.3 3 7.3 9.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 F-box-like PF12937.7 EAU81193.1 - 2.6e-10 40.0 6.6 7.1e-10 38.6 4.7 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU81193.1 - 0.0011 18.8 1.1 0.0037 17.1 0.4 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EAU81193.1 - 0.21 12.1 0.7 23 5.6 0.2 3.9 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU81195.1 - 1.7e-06 27.8 2.0 4.3e-06 26.5 2.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU81195.1 - 6.8e-05 22.6 0.4 6.8e-05 22.6 0.4 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EAU81195.1 - 0.00039 20.3 0.2 0.0013 18.6 0.1 1.9 2 0 0 2 2 2 1 F-box Polysacc_synt_4 PF04669.13 EAU81198.2 - 3.2e-18 66.0 0.8 2.7e-16 59.7 0.8 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis Myb_DNA-binding PF00249.31 EAU81199.2 - 4.6e-08 33.1 0.2 8.4e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ETX_MTX2 PF03318.13 EAU81199.2 - 2.7 7.7 8.0 4.2 7.1 8.0 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Glyco_hydro_47 PF01532.20 EAU81201.1 - 5e-134 447.6 0.0 5.8e-134 447.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 F-box-like PF12937.7 EAU81202.1 - 0.017 15.0 0.2 0.042 13.7 0.2 1.7 1 0 0 1 1 1 0 F-box-like LCE PF14672.6 EAU81202.1 - 1.5 9.5 10.3 4.1 8.1 10.3 1.7 1 0 0 1 1 1 0 Late cornified envelope Lipase_3 PF01764.25 EAU81203.1 - 3.2e-15 56.2 0.0 6.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAU81203.1 - 0.011 16.3 0.1 0.024 15.2 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_MLP1_2 PF07926.12 EAU81206.2 - 6.2e-05 23.1 7.7 6.2e-05 23.1 7.7 1.6 2 0 0 2 2 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 EAU81206.2 - 0.00014 21.2 4.8 0.00023 20.5 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF4201 PF13870.6 EAU81206.2 - 0.0011 18.7 7.5 0.0021 17.8 7.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 EAU81206.2 - 0.0031 17.4 6.0 0.0066 16.3 6.0 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 EAU81206.2 - 0.0039 15.4 5.6 0.0058 14.9 5.6 1.2 1 0 0 1 1 1 1 HOOK protein Cnn_1N PF07989.11 EAU81206.2 - 0.0044 17.1 2.2 0.014 15.5 2.2 1.9 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 DUF4686 PF15742.5 EAU81206.2 - 0.0047 16.1 6.0 0.0082 15.3 6.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) ZapB PF06005.12 EAU81206.2 - 0.0048 17.3 6.5 0.0048 17.3 6.5 2.5 2 1 0 2 2 1 1 Cell division protein ZapB GAS PF13851.6 EAU81206.2 - 0.0061 15.9 7.6 0.012 15.0 7.6 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EAU81206.2 - 0.013 15.5 2.2 0.022 14.7 2.2 1.3 1 0 0 1 1 1 0 Laminin Domain II bZIP_1 PF00170.21 EAU81206.2 - 0.019 15.1 5.5 0.12 12.4 3.3 2.8 1 1 1 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 EAU81206.2 - 0.022 14.8 1.6 0.022 14.8 1.6 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 FPP PF05911.11 EAU81206.2 - 0.038 12.2 7.1 0.018 13.2 5.3 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil PCRF PF03462.18 EAU81206.2 - 0.045 13.6 1.5 0.09 12.6 1.5 1.5 1 0 0 1 1 1 0 PCRF domain DivIC PF04977.15 EAU81206.2 - 0.06 13.1 8.1 0.16 11.7 2.5 2.5 1 1 1 2 2 2 0 Septum formation initiator EzrA PF06160.12 EAU81206.2 - 0.064 11.4 4.3 0.093 10.9 4.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 EAU81206.2 - 0.081 11.8 6.7 0.14 11.0 6.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein BAR_3 PF16746.5 EAU81206.2 - 0.084 12.6 1.4 0.17 11.5 1.4 1.4 1 0 0 1 1 1 0 BAR domain of APPL family UPF0242 PF06785.11 EAU81206.2 - 0.089 12.9 2.7 0.18 11.9 2.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Vip3A_N PF12495.8 EAU81206.2 - 0.1 12.5 0.4 0.15 11.9 0.4 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Rootletin PF15035.6 EAU81206.2 - 0.11 12.5 7.1 0.25 11.3 7.1 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF812 PF05667.11 EAU81206.2 - 0.13 11.2 5.4 0.17 10.7 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TolA_bind_tri PF16331.5 EAU81206.2 - 0.13 12.4 4.2 2 8.5 0.7 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation Syntaxin-6_N PF09177.11 EAU81206.2 - 0.14 12.7 6.4 0.54 10.9 6.2 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 EAU81206.2 - 0.21 11.9 3.7 0.54 10.6 2.8 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 EAU81206.2 - 0.22 11.9 5.0 0.94 9.9 2.9 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain TMF_TATA_bd PF12325.8 EAU81206.2 - 0.29 11.4 8.3 1.1 9.5 6.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.13 EAU81206.2 - 0.3 11.8 2.0 0.78 10.5 2.0 1.7 1 0 0 1 1 1 0 Occludin homology domain Nup54 PF13874.6 EAU81206.2 - 0.51 10.4 5.8 0.85 9.7 5.8 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 XhlA PF10779.9 EAU81206.2 - 0.56 10.4 3.4 5.9 7.2 3.2 2.3 1 1 1 2 2 2 0 Haemolysin XhlA Sec34 PF04136.15 EAU81206.2 - 0.61 9.9 3.1 0.84 9.5 0.8 1.8 1 1 1 2 2 2 0 Sec34-like family NPV_P10 PF05531.12 EAU81206.2 - 1 9.9 3.4 18 5.9 2.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.18 EAU81206.2 - 1.3 9.4 7.8 0.98 9.7 4.1 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper KxDL PF10241.9 EAU81206.2 - 2.2 8.6 11.5 19 5.7 1.6 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein JIP_LZII PF16471.5 EAU81206.2 - 2.4 8.4 6.1 6.6 7.0 4.5 2.3 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II YabA PF06156.13 EAU81206.2 - 5.8 7.6 12.4 0.09 13.4 3.3 2.6 2 1 1 3 3 2 0 Initiation control protein YabA bZIP_2 PF07716.15 EAU81206.2 - 8.9 6.5 9.5 2.1 8.5 2.3 3.0 2 1 0 3 3 2 0 Basic region leucine zipper Fez1 PF06818.15 EAU81206.2 - 9.1 6.7 14.0 0.23 11.9 5.9 2.0 2 0 0 2 2 2 0 Fez1 DUF1972 PF09314.11 EAU81207.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) KDZ PF18758.1 EAU81208.2 - 1.4e-45 155.6 0.4 3.1e-45 154.5 0.4 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU81208.2 - 8.5e-23 80.6 0.2 2.3e-22 79.2 0.2 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU81208.2 - 0.00012 22.2 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU81208.2 - 0.0092 15.8 0.1 0.034 14.0 0.1 2.0 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases DUF4101 PF13355.6 EAU81208.2 - 0.066 13.7 1.4 1.5 9.3 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4101) TTSSLRR PF12468.8 EAU81209.1 - 4.5 7.6 8.9 1 9.7 0.2 2.9 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein FAM199X PF15814.5 EAU81209.1 - 6.2 5.8 26.4 24 3.8 20.9 3.0 2 1 1 3 3 3 0 Protein family FAM199X Macoilin PF09726.9 EAU81209.1 - 6.3 5.2 12.8 10 4.5 12.8 1.3 1 0 0 1 1 1 0 Macoilin family Pkinase_fungal PF17667.1 EAU81211.2 - 2.9e-43 148.2 0.0 1e-23 83.8 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU81211.2 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC_membrane PF00664.23 EAU81212.1 - 4.3e-36 125.0 5.7 6e-36 124.5 5.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAU81212.1 - 4.9e-27 95.1 0.0 9.5e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EAU81212.1 - 5.9e-05 23.5 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAU81212.1 - 0.0025 17.8 0.0 0.0097 15.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAU81212.1 - 0.008 16.7 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EAU81212.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EAU81212.1 - 0.016 15.1 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAU81212.1 - 0.016 15.5 0.2 0.1 12.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EAU81212.1 - 0.039 13.6 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EAU81212.1 - 0.045 13.3 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EAU81212.1 - 0.073 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 EAU81212.1 - 0.097 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 EAU81212.1 - 0.11 12.7 0.1 0.51 10.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAU81212.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_membrane PF00664.23 EAU81213.2 - 1.2e-46 159.6 4.2 3.4e-46 158.1 4.2 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAU81213.2 - 1.2e-09 38.9 0.1 1.2e-05 25.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EAU81213.2 - 0.0041 17.5 0.1 0.012 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EAU81213.2 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAU81213.2 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EAU81213.2 - 0.01 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EAU81213.2 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EAU81213.2 - 0.08 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU81213.2 - 0.088 13.1 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EAU81213.2 - 0.11 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.26 EAU81213.2 - 0.13 11.9 0.0 0.82 9.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EAU81213.2 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PBP_like_2 PF12849.7 EAU81214.1 - 8.8e-11 42.0 0.1 1.2e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 PBP superfamily domain Pkinase_fungal PF17667.1 EAU81216.2 - 1.8e-28 99.5 0.0 3.4e-17 62.3 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 EAU81217.2 - 5.4e-42 144.0 0.0 2.8e-23 82.3 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU81217.2 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PI-PLC-X PF00388.19 EAU81219.2 - 2.2e-56 189.5 0.0 4.3e-56 188.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAU81219.2 - 1.1e-39 135.3 0.0 2.1e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EAU81219.2 - 7.6e-09 35.8 0.0 7.6e-08 32.6 0.0 2.4 1 1 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EAU81219.2 - 6.2e-07 29.8 1.2 0.00027 21.3 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAU81219.2 - 7.2e-05 22.1 0.2 0.013 15.0 0.0 3.1 2 0 0 2 2 2 1 EF hand EF-hand_like PF09279.11 EAU81219.2 - 0.0001 22.7 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 EAU81219.2 - 0.0089 15.9 3.0 0.87 9.7 0.0 3.9 4 1 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 EAU81219.2 - 0.027 14.3 0.1 1.6 8.7 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain pair Spore_YpjB PF09577.10 EAU81219.2 - 0.033 14.0 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) EF-hand_10 PF14788.6 EAU81219.2 - 0.063 13.1 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 EF hand DUF4470 PF14737.6 EAU81220.2 - 0.00036 20.6 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_19 PF14559.6 EAU81220.2 - 0.017 15.6 0.0 0.051 14.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAU81220.2 - 0.053 14.2 0.2 0.2 12.3 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU81220.2 - 0.062 13.4 1.3 14 6.1 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU81220.2 - 0.16 12.2 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 FTSW_RODA_SPOVE PF01098.19 EAU81220.2 - 0.17 10.9 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 Cell cycle protein Chromo_2 PF18704.1 EAU81220.2 - 0.53 10.6 3.4 2.2 8.6 0.6 2.7 2 0 0 2 2 2 0 Chromatin organization modifier domain 2 Ank_2 PF12796.7 EAU81222.2 - 1.1e-69 231.0 10.4 1e-17 64.5 0.1 7.1 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU81222.2 - 3.6e-63 202.0 3.4 5.7e-06 26.3 0.0 12.5 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 EAU81222.2 - 3.1e-52 172.8 23.2 6.4e-06 26.4 0.1 13.1 12 1 1 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 EAU81222.2 - 1.7e-48 162.0 23.0 9.5e-09 35.4 0.1 10.8 3 1 9 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU81222.2 - 2.3e-43 146.0 13.4 2.5e-08 34.3 0.1 10.7 1 1 10 11 11 11 11 Ankyrin repeats (many copies) UBA_4 PF14555.6 EAU81222.2 - 1.4e-07 31.2 1.8 8 6.4 0.0 8.0 8 0 0 8 8 8 1 UBA-like domain NapD PF03927.13 EAU81222.2 - 0.00027 20.9 5.5 11 6.1 0.0 6.1 3 2 2 6 6 6 1 NapD protein AAA_22 PF13401.6 EAU81222.2 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Clp_N PF02861.20 EAU81222.2 - 0.00078 19.5 6.3 78 3.5 0.1 8.3 9 0 0 9 9 8 0 Clp amino terminal domain, pathogenicity island component DUF1858 PF08984.11 EAU81222.2 - 0.013 15.7 4.9 1.7e+02 2.4 0.0 6.7 8 0 0 8 8 7 0 Domain of unknown function (DUF1858) WIYLD PF10440.9 EAU81222.2 - 0.057 13.2 1.3 56 3.6 0.0 5.2 7 0 0 7 7 7 0 Ubiquitin-binding WIYLD domain DUF2075 PF09848.9 EAU81222.2 - 0.064 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EAU81222.2 - 0.15 11.9 0.0 0.64 9.9 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Nitro_FeMo-Co PF02579.17 EAU81222.2 - 0.17 12.2 9.1 26 5.2 0.2 5.0 3 2 2 5 5 5 0 Dinitrogenase iron-molybdenum cofactor NMT1_2 PF13379.6 EAU81222.2 - 0.35 10.5 6.7 11 5.6 1.1 3.8 2 2 2 4 4 4 0 NMT1-like family 3HCDH_RFF PF18321.1 EAU81222.2 - 6.7 7.2 6.3 33 5.0 0.0 5.0 6 0 0 6 6 3 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain AMP-binding PF00501.28 EAU81223.1 - 2.7e-96 322.8 0.1 3.2e-96 322.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU81223.1 - 4.5e-25 88.4 0.1 5.9e-24 84.8 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EAU81223.1 - 2.6e-14 52.9 0.9 7.9e-14 51.3 0.9 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Crp PF00325.20 EAU81223.1 - 0.0027 17.3 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family DUF2461 PF09365.10 EAU81224.2 - 4.9e-44 150.8 0.2 1.4e-43 149.3 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) Ank_2 PF12796.7 EAU81226.2 - 1.9e-80 265.5 9.5 3.4e-18 66.0 0.0 6.0 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU81226.2 - 4.9e-53 170.9 0.9 2.2e-05 24.5 0.0 10.7 10 0 0 10 10 10 8 Ankyrin repeat Ank PF00023.30 EAU81226.2 - 1.5e-46 154.8 19.4 8.1e-06 26.0 0.2 10.9 10 1 1 11 11 10 9 Ankyrin repeat Ank_5 PF13857.6 EAU81226.2 - 1.1e-41 140.4 13.0 1.6e-08 34.7 0.3 8.2 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU81226.2 - 5.9e-32 109.6 15.2 8.3e-05 23.1 0.1 8.7 1 1 7 8 8 8 7 Ankyrin repeats (many copies) NapD PF03927.13 EAU81226.2 - 1.7e-05 24.8 0.8 21 5.3 0.0 6.2 2 2 3 6 6 6 0 NapD protein AAA_22 PF13401.6 EAU81226.2 - 9.9e-05 22.6 0.0 0.00034 20.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU81226.2 - 0.0064 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain UBA_4 PF14555.6 EAU81226.2 - 0.007 16.2 0.0 10 6.0 0.0 5.1 6 0 0 6 6 6 1 UBA-like domain NB-ARC PF00931.22 EAU81226.2 - 0.01 15.0 0.0 0.023 13.9 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EAU81226.2 - 0.03 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF1858 PF08984.11 EAU81226.2 - 0.12 12.6 4.6 1.7e+02 2.4 0.0 5.9 7 0 0 7 7 6 0 Domain of unknown function (DUF1858) Phenol_Hydrox PF02332.18 EAU81226.2 - 0.81 9.2 4.1 45 3.5 0.1 3.2 1 1 1 4 4 4 0 Methane/Phenol/Toluene Hydroxylase Nitro_FeMo-Co PF02579.17 EAU81226.2 - 0.86 10.0 4.4 72 3.8 0.1 4.3 2 1 4 6 6 6 0 Dinitrogenase iron-molybdenum cofactor Imm53 PF15580.6 EAU81226.2 - 7.1 6.4 8.5 50 3.7 0.2 4.5 2 2 0 4 4 4 0 Immunity protein 53 HHH PF00633.23 EAU81226.2 - 8.6 6.4 7.7 1e+02 3.0 0.1 4.7 4 0 0 4 4 4 0 Helix-hairpin-helix motif Tryp_inh PF17983.1 EAU81227.2 - 0.014 15.5 6.6 0.014 15.5 6.6 2.1 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 DUF1515 PF07439.11 EAU81229.2 - 0.18 11.9 0.1 0.18 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Zn_clus PF00172.18 EAU81232.2 - 1.7e-05 24.8 9.2 2.9e-05 24.1 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EAU81232.2 - 0.0082 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF104 PF01954.16 EAU81232.2 - 0.02 15.3 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF104 Glyco_hydro_1 PF00232.18 EAU81233.2 - 1.7e-143 478.3 3.1 1.4e-142 475.4 3.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 GFO_IDH_MocA PF01408.22 EAU81234.2 - 9.3e-15 55.5 0.1 2e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAU81234.2 - 7e-07 29.3 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EAU81234.2 - 0.036 14.7 0.3 0.073 13.7 0.3 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Inhibitor_I66 PF16850.5 EAU81235.1 - 3.9e-40 137.1 0.0 4.3e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 RicinB_lectin_2 PF14200.6 EAU81235.1 - 0.013 16.2 0.0 0.2 12.4 0.0 2.1 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Inhibitor_I66 PF16850.5 EAU81236.1 - 3.1e-55 186.1 0.0 3.4e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 Abhydrolase_3 PF07859.13 EAU81237.2 - 1.3e-55 188.6 0.3 1.2e-48 165.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU81237.2 - 0.062 12.8 0.1 10 5.5 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.28 EAU81237.2 - 0.073 11.9 0.0 0.17 10.7 0.0 1.6 1 1 0 1 1 1 0 Carboxylesterase family SSP160 PF06933.11 EAU81237.2 - 3 5.9 10.1 4.1 5.5 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-RVT PF13966.6 EAU81240.2 - 0.0057 17.4 0.1 0.013 16.2 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_S32 PF05579.13 EAU81240.2 - 0.032 13.4 0.2 0.97 8.6 0.4 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 LRR_4 PF12799.7 EAU81241.1 - 0.036 14.5 6.1 0.19 12.2 0.8 4.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAU81242.2 - 0.042 13.6 0.5 1.1 9.0 0.1 3.4 2 2 1 3 3 3 0 Leucine rich repeat Erf4 PF10256.9 EAU81245.1 - 1.3e-05 25.2 0.1 0.00026 21.1 0.0 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.6 EAU81245.1 - 0.004 17.7 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF3179 PF11376.8 EAU81245.1 - 0.21 10.9 2.4 0.37 10.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) Remorin_C PF03763.13 EAU81245.1 - 0.41 10.5 32.6 0.097 12.6 17.8 2.6 1 1 1 2 2 2 0 Remorin, C-terminal region Neur_chan_memb PF02932.16 EAU81245.1 - 9.4 6.2 8.0 13 5.8 8.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 EAU81246.2 - 0.4 10.6 5.2 0.56 10.2 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Borrelia_P83 PF05262.11 EAU81246.2 - 0.96 7.9 13.4 1.2 7.5 13.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MscL PF01741.18 EAU81263.2 - 0.013 15.8 1.1 0.017 15.4 0.8 1.4 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Cpta_toxin PF07254.12 EAU81263.2 - 0.032 14.2 0.7 0.054 13.5 0.1 1.7 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system DHHC PF01529.20 EAU81263.2 - 0.11 12.6 2.3 0.1 12.7 1.3 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Smac_DIABLO PF09057.10 EAU81265.2 - 0.39 10.0 3.3 1.1 8.5 3.3 1.7 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Fzo_mitofusin PF04799.13 EAU81266.2 - 0.012 15.2 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 fzo-like conserved region Phasin PF05597.11 EAU81266.2 - 0.012 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ATG16 PF08614.11 EAU81266.2 - 0.015 15.5 0.1 0.024 14.8 0.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 EAU81266.2 - 0.016 15.2 0.5 0.033 14.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf-C3HC4_3 PF13920.6 EAU81267.2 - 0.41 10.5 9.1 0.8 9.6 9.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4360 PF14273.6 EAU81273.2 - 7.9e-43 146.4 1.5 1e-42 146.1 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 EAU81274.2 - 1.3e-24 87.0 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 EAU81275.1 - 2.5e-39 135.0 5.3 2.8e-39 134.8 5.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase_fungal PF17667.1 EAU81277.2 - 1.6e-47 162.2 0.0 3.9e-47 160.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU81277.2 - 0.0032 16.9 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain F-box-like PF12937.7 EAU81282.1 - 0.0029 17.5 0.0 0.0072 16.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like PI-PLC-X PF00388.19 EAU81283.1 - 1.5e-54 183.5 0.0 2.5e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAU81283.1 - 3e-43 146.8 0.2 1.6e-42 144.4 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.6 EAU81283.1 - 9.1e-07 29.2 1.2 3e-06 27.6 1.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair C2 PF00168.30 EAU81283.1 - 1.1e-06 28.9 0.0 0.014 15.7 0.0 3.1 3 0 0 3 3 3 2 C2 domain EF-hand_10 PF14788.6 EAU81283.1 - 9.9e-06 25.3 0.6 2.1e-05 24.3 0.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EAU81283.1 - 2.9e-05 23.3 1.0 0.011 15.2 0.4 2.9 2 0 0 2 2 2 2 EF hand PH_14 PF17787.1 EAU81283.1 - 0.00053 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_like PF09279.11 EAU81283.1 - 0.00079 19.9 0.2 0.0022 18.4 0.2 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.6 EAU81283.1 - 0.0059 16.4 4.4 0.21 11.6 1.1 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_4 PF12763.7 EAU81283.1 - 0.13 12.2 0.1 0.48 10.4 0.1 1.9 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF4470 PF14737.6 EAU81284.1 - 5e-09 36.2 0.0 7.6e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EAU81284.1 - 1.3e-05 24.8 0.6 2.3e-05 24.0 0.6 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EAU81284.1 - 2.2e-05 24.2 1.3 0.0026 17.7 0.7 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU81284.1 - 0.00049 19.8 2.3 0.0036 17.1 0.9 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU81284.1 - 0.018 15.7 0.1 0.052 14.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU81284.1 - 0.05 13.8 0.8 0.2 12.0 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU81284.1 - 0.13 12.6 0.8 3.2 8.1 0.9 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_3 PF07720.12 EAU81284.1 - 0.16 12.0 2.1 0.23 11.5 0.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat CAAD PF14159.6 EAU81286.2 - 0.072 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase COX7C PF02935.16 EAU81286.2 - 0.38 11.0 1.4 0.67 10.3 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc FH2 PF02181.23 EAU81287.2 - 0.0015 17.7 1.7 0.003 16.8 1.6 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain BLOC1_2 PF10046.9 EAU81287.2 - 0.0024 18.1 2.5 0.0035 17.6 1.3 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 MAD PF05557.13 EAU81287.2 - 0.0029 16.0 5.2 0.0037 15.7 5.2 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Spc7 PF08317.11 EAU81287.2 - 0.0058 15.6 7.9 0.0079 15.1 7.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EAU81287.2 - 0.017 14.7 2.1 0.019 14.5 2.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EAU81287.2 - 0.026 14.6 0.9 0.026 14.6 0.9 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) MMS22L_C PF14911.6 EAU81287.2 - 0.026 13.6 1.3 0.032 13.3 1.3 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Jnk-SapK_ap_N PF09744.9 EAU81287.2 - 0.051 13.8 8.2 0.088 13.0 8.2 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Bestrophin PF01062.21 EAU81287.2 - 0.059 12.8 0.4 0.086 12.2 0.3 1.4 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel ERM PF00769.19 EAU81287.2 - 0.08 12.7 10.6 0.12 12.2 10.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Aida_N PF08910.10 EAU81287.2 - 0.095 13.1 3.4 0.13 12.6 1.9 1.8 1 1 1 2 2 2 0 Aida N-terminus SNARE PF05739.19 EAU81287.2 - 0.1 12.6 0.1 17 5.5 0.0 2.6 3 0 0 3 3 2 0 SNARE domain RabGAP-TBC PF00566.18 EAU81287.2 - 0.11 12.2 0.5 0.29 10.7 0.1 1.7 1 1 1 2 2 2 0 Rab-GTPase-TBC domain MCU PF04678.13 EAU81287.2 - 0.12 12.4 2.0 0.16 12.0 2.0 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DHR10 PF18595.1 EAU81287.2 - 0.12 12.4 11.4 0.037 14.1 6.1 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain GHL15 PF14885.6 EAU81287.2 - 0.13 12.2 0.1 2.8 7.8 0.1 2.0 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Laminin_II PF06009.12 EAU81287.2 - 0.17 11.9 4.8 0.37 10.8 4.8 1.6 1 1 0 1 1 1 0 Laminin Domain II zf-C4H2 PF10146.9 EAU81287.2 - 0.2 12.0 7.8 0.28 11.5 7.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein EMP24_GP25L PF01105.24 EAU81287.2 - 0.26 11.2 4.3 2 8.3 4.1 2.1 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Uso1_p115_C PF04871.13 EAU81287.2 - 0.31 11.4 6.6 0.63 10.4 6.6 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Snapin_Pallidin PF14712.6 EAU81287.2 - 0.32 11.5 6.1 0.12 12.8 2.1 2.2 1 1 0 2 2 2 0 Snapin/Pallidin Tup_N PF08581.10 EAU81287.2 - 0.33 11.3 9.5 1.6 9.1 1.4 3.0 2 1 1 3 3 3 0 Tup N-terminal DUF4988 PF16378.5 EAU81287.2 - 0.35 10.5 1.9 4.8 6.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function FlaC_arch PF05377.11 EAU81287.2 - 0.49 10.8 3.8 5.9 7.4 0.6 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) WD40_alt PF14077.6 EAU81287.2 - 0.66 9.9 18.4 0.81 9.6 1.8 3.7 2 1 2 4 4 4 0 Alternative WD40 repeat motif Paralemmin PF03285.15 EAU81287.2 - 0.67 9.5 8.2 2.5 7.6 8.2 1.7 1 1 0 1 1 1 0 Paralemmin Ax_dynein_light PF10211.9 EAU81287.2 - 0.76 9.7 10.7 0.21 11.5 2.6 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain ATG16 PF08614.11 EAU81287.2 - 0.83 9.8 12.7 2.1 8.5 12.7 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 EAU81287.2 - 0.98 9.8 9.0 0.16 12.4 1.2 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-H PF05837.12 EAU81287.2 - 1.4 9.4 7.9 2.3 8.7 7.9 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YabA PF06156.13 EAU81287.2 - 1.8 9.3 6.5 2.1 9.0 3.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA GrpE PF01025.19 EAU81287.2 - 2.8 7.6 9.1 23 4.6 9.0 1.9 1 1 0 1 1 1 0 GrpE DUF3287 PF11690.8 EAU81287.2 - 6.4 6.5 7.6 1.1 9.0 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) XhlA PF10779.9 EAU81287.2 - 6.6 7.0 11.1 0.6 10.3 2.7 2.7 2 1 1 3 3 3 0 Haemolysin XhlA DivIC PF04977.15 EAU81287.2 - 7.5 6.4 9.0 5.8 6.8 0.9 2.7 2 1 1 3 3 3 0 Septum formation initiator AcetDehyd-dimer PF09290.11 EAU81289.2 - 0.092 12.9 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation LegC3_N PF18654.1 EAU81293.1 - 0.14 11.3 6.0 0.19 10.9 4.1 1.8 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain KDZ PF18758.1 EAU81294.2 - 3.6e-52 177.2 0.0 5.8e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EAU81294.2 - 4.4e-09 36.4 0.2 9.4e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU81294.2 - 2.8e-06 27.4 0.2 5.5e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases AT_hook PF02178.19 EAU81294.2 - 0.024 14.5 23.5 0.47 10.5 6.6 3.1 2 0 0 2 2 2 0 AT hook motif CxC3 PF18804.1 EAU81294.2 - 0.031 14.1 1.8 0.17 11.7 0.1 2.3 2 0 0 2 2 2 0 CxC3 like cysteine cluster associated with KDZ transposases OrsD PF12013.8 EAU81294.2 - 0.045 14.2 0.1 0.35 11.3 0.0 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D ORC6 PF05460.13 EAU81294.2 - 7.8 5.7 9.0 13 4.9 9.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PHD PF00628.29 EAU81295.2 - 6e-05 22.9 8.5 0.00014 21.6 8.5 1.7 1 0 0 1 1 1 1 PHD-finger YfiO PF13525.6 EAU81295.2 - 0.1 12.3 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein PHD_4 PF16866.5 EAU81295.2 - 0.3 11.2 6.2 0.75 9.9 6.2 1.7 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 EAU81295.2 - 0.93 9.7 4.6 2.6 8.2 4.6 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 EAU81295.2 - 3.6 7.5 7.7 0.26 11.2 1.3 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Metallophos PF00149.28 EAU81296.2 - 1.1e-10 42.4 0.4 1.8e-10 41.7 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU81296.2 - 9.8e-06 25.9 0.0 0.00023 21.4 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EAU81297.2 - 2.6e-12 47.7 0.9 5.4e-12 46.7 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU81297.2 - 1.3e-05 25.5 0.1 0.00025 21.3 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pyr_redox_2 PF07992.14 EAU81298.2 - 8.8e-35 120.4 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EAU81298.2 - 1.6e-20 73.2 0.0 3.7e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Fer2_BFD PF04324.15 EAU81298.2 - 2.4e-15 56.6 3.7 7.4e-11 42.2 3.3 2.8 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 EAU81298.2 - 1.3e-11 44.2 0.0 3.2e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.27 EAU81298.2 - 5.4e-11 42.9 0.0 1.4e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EAU81298.2 - 9.8e-10 38.3 0.0 4.9e-09 36.1 0.0 2.3 2 1 0 2 2 2 1 Rieske-like [2Fe-2S] domain Rubredoxin_C PF18267.1 EAU81298.2 - 0.00028 20.8 0.1 0.042 13.8 0.1 3.5 3 0 0 3 3 3 1 Rubredoxin NAD+ reductase C-terminal domain Rieske PF00355.26 EAU81298.2 - 0.088 12.8 0.2 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain MFS_1 PF07690.16 EAU81299.2 - 1.4e-29 103.2 18.2 1.4e-29 103.2 18.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily YnfE PF17452.2 EAU81299.2 - 0.068 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized YnfE-like DUF3242 PF11586.8 EAU81299.2 - 0.074 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Mcp5_PH PF12814.7 EAU81299.2 - 0.19 11.9 0.1 0.33 11.1 0.1 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Sugar_tr PF00083.24 EAU81299.2 - 0.32 9.8 19.5 0.011 14.7 7.7 2.8 3 0 0 3 3 3 0 Sugar (and other) transporter Oxidored_molyb PF00174.19 EAU81300.2 - 1.8e-56 190.4 0.0 3.4e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EAU81300.2 - 1.7e-50 170.6 0.1 2.8e-50 169.9 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 EAU81300.2 - 1.5e-25 89.4 0.0 3.5e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EAU81300.2 - 3.3e-24 85.6 0.0 7.7e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EAU81300.2 - 2.3e-20 72.5 0.0 5.6e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EAU81300.2 - 0.00036 20.7 0.0 0.016 15.4 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Phytase PF02333.15 EAU81300.2 - 0.19 10.6 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Phytase DNA_pol3_finger PF17657.1 EAU81301.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit finger domain DUF1996 PF09362.10 EAU81302.2 - 3.2e-65 220.4 0.0 4.3e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CHAT PF12770.7 EAU81303.2 - 3.3e-13 49.7 0.6 2.7e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.6 EAU81303.2 - 2.2e-09 36.9 15.1 0.00058 19.6 0.0 9.0 10 2 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAU81303.2 - 0.00082 19.6 12.8 1.7 9.0 0.1 5.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU81303.2 - 0.0083 16.1 4.1 42 4.5 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU81303.2 - 0.11 12.7 9.6 18 5.7 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU81303.2 - 0.15 12.0 3.7 24 4.9 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU81303.2 - 0.17 12.8 11.7 12 7.0 0.1 6.1 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAU81303.2 - 0.28 11.7 4.5 14 6.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU81303.2 - 1.5 8.5 6.6 13 5.5 0.1 4.9 7 0 0 7 7 7 0 TPR repeat NLE PF08154.12 EAU81305.1 - 1.5e-14 54.3 0.0 3.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 EAU81305.1 - 5.1e-12 46.1 9.1 0.016 16.0 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat OspD PF03207.13 EAU81305.1 - 0.058 12.7 0.1 0.09 12.1 0.1 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) Prominin PF05478.11 EAU81309.2 - 0.0036 15.4 1.0 0.0051 14.8 1.0 1.1 1 0 0 1 1 1 1 Prominin EspB PF05802.11 EAU81309.2 - 0.044 13.8 3.8 0.15 12.0 0.6 2.3 2 0 0 2 2 2 0 Enterobacterial EspB protein DNA_primase_S PF01896.19 EAU81311.2 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA primase small subunit Pectate_lyase_2 PF06917.12 EAU81311.2 - 0.19 10.2 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Periplasmic pectate lyase DUF1360 PF07098.11 EAU81314.1 - 1.2 9.1 4.6 0.74 9.8 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1360) DUF1394 PF07159.12 EAU81316.1 - 0.0041 16.4 0.0 0.0043 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) ERM PF00769.19 EAU81317.1 - 0.0093 15.8 2.5 0.011 15.5 2.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MPS2 PF17060.5 EAU81317.1 - 0.019 14.3 0.2 0.022 14.1 0.2 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Spc7 PF08317.11 EAU81317.1 - 0.047 12.6 2.3 0.066 12.1 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 EAU81317.1 - 0.13 12.4 0.7 0.23 11.6 0.7 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.9 EAU81317.1 - 2.9 6.9 6.8 0.2 10.7 2.2 1.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 KDZ PF18758.1 EAU81323.2 - 8.6e-46 156.3 0.4 1.4e-45 155.7 0.4 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU81323.2 - 2.3e-21 75.9 1.7 4.1e-21 75.1 0.3 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU81323.2 - 0.0047 17.0 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU81323.2 - 0.09 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases HMG_box_2 PF09011.10 EAU81324.1 - 1.4e-05 25.6 2.0 6.7e-05 23.4 2.0 2.3 1 0 0 1 1 1 1 HMG-box domain DUF5644 PF18712.1 EAU81325.2 - 0.09 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5644) Csm1_N PF18504.1 EAU81325.2 - 0.36 11.2 5.3 1.4 9.3 1.3 3.2 1 1 2 3 3 3 0 Csm1 N-terminal domain TctB PF07331.11 EAU81329.2 - 0.0026 18.1 2.1 0.003 17.8 2.1 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctB family Pkinase_fungal PF17667.1 EAU81338.1 - 1.8e-37 129.1 0.0 3.8e-25 88.5 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU81338.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4051 PF13260.6 EAU81339.1 - 0.03 14.1 0.1 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Peroxin-3 PF04882.12 EAU81340.1 - 9.5e-116 387.6 0.4 3.4e-96 323.1 7.8 2.6 2 1 0 2 2 2 2 Peroxin-3 PIN_6 PF17146.4 EAU81341.1 - 0.12 12.9 0.2 9.7 6.8 0.1 2.3 2 0 0 2 2 2 0 PIN domain of ribonuclease Mitochondr_Som1 PF11093.8 EAU81341.1 - 0.15 12.1 0.1 0.48 10.4 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial export protein Som1 eIF-3c_N PF05470.12 EAU81341.1 - 0.28 9.5 3.5 0.63 8.3 3.8 1.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 EAU81341.1 - 0.39 8.9 12.8 0.54 8.5 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Plavaka PF18759.1 EAU81343.2 - 2.2e-28 99.5 0.0 4.2e-14 52.5 0.0 2.5 1 1 1 2 2 2 2 Plavaka transposase Acetyltransf_10 PF13673.7 EAU81346.2 - 1.8e-10 40.9 0.0 2.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU81346.2 - 1.7e-08 34.8 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU81346.2 - 7.2e-08 32.7 0.0 9.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fil_haemagg_2 PF13332.6 EAU81346.2 - 0.034 14.3 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Hemagglutinin repeat baeRF_family10 PF18854.1 EAU81346.2 - 0.062 13.6 0.0 0.099 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Acetyltransf_9 PF13527.7 EAU81346.2 - 0.073 13.1 0.0 0.5 10.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAU81346.2 - 0.1 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Form-deh_trans PF09163.11 EAU81346.2 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane YL1 PF05764.13 EAU81347.1 - 0.0014 18.8 2.9 0.0018 18.4 2.9 1.1 1 0 0 1 1 1 1 YL1 nuclear protein CCDC24 PF15669.5 EAU81347.1 - 0.025 14.5 0.2 0.04 13.8 0.2 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family CDC45 PF02724.14 EAU81347.1 - 0.046 12.0 0.9 0.06 11.6 0.9 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EAU81347.1 - 0.43 9.9 5.9 0.61 9.4 5.9 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EAU81347.1 - 0.9 7.6 9.3 1.5 6.8 9.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Aldedh PF00171.22 EAU81348.1 - 3.5e-126 421.4 0.0 4.1e-126 421.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EAU81348.1 - 7.8e-07 28.5 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) AA_kinase PF00696.28 EAU81349.2 - 6.3e-39 134.0 0.0 6.9e-38 130.6 0.0 2.3 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EAU81349.2 - 7.1e-11 41.7 3.3 1.6e-08 34.2 0.2 2.8 3 0 0 3 3 3 2 ACT domain ACT PF01842.25 EAU81349.2 - 4.5e-10 39.1 5.2 5.8e-06 26.0 0.1 3.3 3 0 0 3 3 3 2 ACT domain FMN_red PF03358.15 EAU81349.2 - 0.085 12.6 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Pkinase_fungal PF17667.1 EAU81350.2 - 5.3e-25 88.1 0.0 1.2e-17 63.8 0.0 2.7 2 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU81350.2 - 0.0076 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU81350.2 - 0.039 13.9 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCCH PF00642.24 EAU81351.2 - 3e-10 39.7 6.9 0.0027 17.6 3.1 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EAU81351.2 - 5.6e-08 32.5 0.0 8.6e-07 28.7 0.0 2.6 3 0 0 3 3 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EAU81351.2 - 9.4e-08 32.7 0.1 0.52 11.0 0.0 3.6 3 0 0 3 3 3 2 Torus domain zf-C3HC4_4 PF15227.6 EAU81351.2 - 3.8e-06 27.0 5.5 3.8e-06 27.0 5.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EAU81351.2 - 7.8e-06 25.6 2.9 7.8e-06 25.6 2.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU81351.2 - 2.9e-05 24.0 5.1 7e-05 22.8 5.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAU81351.2 - 3.8e-05 23.5 5.3 9.8e-05 22.2 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 EAU81351.2 - 0.00014 21.8 16.1 0.015 15.3 0.2 3.5 3 0 0 3 3 3 2 Zinc finger domain zf-C3HC4_3 PF13920.6 EAU81351.2 - 0.00055 19.7 2.3 0.00055 19.7 2.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU81351.2 - 0.0028 17.6 4.7 0.0076 16.2 4.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH_4 PF18044.1 EAU81351.2 - 0.0032 17.2 8.8 0.41 10.5 2.1 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger Limkain-b1 PF11608.8 EAU81351.2 - 0.0083 16.2 0.0 0.1 12.7 0.0 2.4 2 0 0 2 2 2 1 Limkain b1 zf-RING_2 PF13639.6 EAU81351.2 - 0.0084 16.4 4.6 0.0084 16.4 4.6 2.2 2 0 0 2 2 1 1 Ring finger domain Fer2 PF00111.27 EAU81351.2 - 0.022 14.7 1.3 0.054 13.5 1.3 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-CCCH_3 PF15663.5 EAU81351.2 - 0.032 14.4 1.1 5.1 7.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger containing family GST_N PF02798.20 EAU81355.2 - 9.5e-14 51.5 0.1 2.3e-13 50.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU81355.2 - 3.7e-09 36.9 0.0 7.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAU81355.2 - 2.9e-08 33.8 0.0 5.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAU81355.2 - 7.5e-06 26.2 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU81355.2 - 0.00093 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EAU81355.2 - 0.1 12.9 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Phage_portal_2 PF05136.13 EAU81356.2 - 0.057 12.6 0.1 0.081 12.1 0.1 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family Macoilin PF09726.9 EAU81356.2 - 0.17 10.4 0.1 0.21 10.1 0.1 1.1 1 0 0 1 1 1 0 Macoilin family Pox_A_type_inc PF04508.12 EAU81356.2 - 0.45 10.5 4.9 0.85 9.6 4.9 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AdoHcyase PF05221.17 EAU81357.2 - 6.8e-136 452.3 0.0 2.1e-75 253.7 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EAU81357.2 - 1.2e-85 285.5 0.6 1.9e-85 284.9 0.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EAU81357.2 - 3.8e-08 32.9 0.0 8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EAU81357.2 - 3.4e-05 23.5 0.1 5.7e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EAU81357.2 - 0.0015 18.8 0.1 0.0042 17.3 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 EAU81357.2 - 0.066 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EAU81357.2 - 0.13 12.7 0.1 0.39 11.2 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Forkhead_N PF08430.12 EAU81363.1 - 0.43 11.2 4.4 12 6.5 0.2 2.6 2 0 0 2 2 2 0 Forkhead N-terminal region ABC_tran PF00005.27 EAU81372.2 - 9.9e-19 68.2 0.0 1.6e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AA_permease_N PF08403.10 EAU81372.2 - 0.013 15.0 0.0 0.039 13.4 0.0 1.8 1 0 0 1 1 1 0 Amino acid permease N-terminal ABC_membrane PF00664.23 EAU81372.2 - 0.027 14.1 2.6 0.052 13.2 2.2 1.6 1 1 0 1 1 1 0 ABC transporter transmembrane region DUF4405 PF14358.6 EAU81372.2 - 0.078 13.5 0.5 0.16 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) VirC1 PF07015.11 EAU81373.2 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein zf-MYND PF01753.18 EAU81374.2 - 1.1e-09 38.1 16.6 2.8e-09 36.9 16.6 1.7 1 0 0 1 1 1 1 MYND finger DUF3136 PF11334.8 EAU81374.2 - 0.08 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Bestrophin PF01062.21 EAU81378.1 - 2.6e-37 128.8 0.1 6.1e-20 71.8 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4164 PF13747.6 EAU81379.2 - 0.27 11.5 3.3 0.43 10.9 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TT_ORF2 PF02957.15 EAU81379.2 - 1.2 10.1 4.3 0.76 10.7 0.4 2.4 2 0 0 2 2 2 0 TT viral ORF2 p450 PF00067.22 EAU81380.2 - 4.3e-67 226.8 0.0 4.9e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GP44 PF17510.2 EAU81380.2 - 0.14 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Gene product 44 Glyco_hydro_88 PF07470.13 EAU81382.1 - 1e-16 61.0 0.0 4.1e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.13 EAU81383.2 - 8.1e-13 48.2 0.1 2.7e-12 46.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 p450 PF00067.22 EAU81384.2 - 9e-64 215.9 0.0 1.1e-63 215.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EPL1 PF10513.9 EAU81386.1 - 4.1e-23 82.5 0.1 4.1e-23 82.5 0.1 2.7 3 0 0 3 3 3 1 Enhancer of polycomb-like ANAPC_CDC26 PF10471.9 EAU81386.1 - 0.0022 18.8 3.9 0.0022 18.8 3.9 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex APC subunit CDC26 Pesticin PF16754.5 EAU81386.1 - 0.12 12.4 0.2 1.2 9.1 0.1 2.3 2 0 0 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term FlgM PF04316.13 EAU81386.1 - 0.18 12.2 0.0 0.18 12.2 0.0 3.0 4 0 0 4 4 4 0 Anti-sigma-28 factor, FlgM DUF1974 PF09317.11 EAU81386.1 - 0.6 9.6 4.1 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1974) Oxidored-like PF09791.9 EAU81387.2 - 3e-20 71.6 0.8 7.2e-20 70.4 0.8 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal CCSAP PF15748.5 EAU81387.2 - 9.4 6.3 13.6 0.81 9.8 4.5 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Transp_cyt_pur PF02133.15 EAU81388.1 - 1.1e-23 83.7 39.1 1.2e-22 80.3 39.1 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3179 PF11376.8 EAU81388.1 - 0.26 10.6 0.1 0.57 9.5 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3179) Reticulon PF02453.17 EAU81388.1 - 0.83 9.6 6.7 0.16 11.9 1.6 2.5 2 0 0 2 2 2 0 Reticulon Transp_cyt_pur PF02133.15 EAU81390.1 - 2.2e-30 105.8 38.8 6e-30 104.4 38.8 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1211 PF06736.11 EAU81390.1 - 0.036 14.5 7.8 7.8 7.0 0.6 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1211) MutS_V PF00488.21 EAU81391.2 - 1.6e-83 279.4 0.1 3.1e-83 278.4 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAU81391.2 - 1.8e-35 122.9 0.1 4.1e-35 121.7 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EAU81391.2 - 1e-16 61.1 0.8 2.6e-16 59.7 0.8 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EAU81391.2 - 2.8e-14 53.6 0.0 9e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 EAU81391.2 - 6.8e-09 36.0 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 EAU81391.2 - 0.089 12.4 0.0 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain EMP24_GP25L PF01105.24 EAU81391.2 - 0.18 11.8 1.2 2.2 8.2 0.0 2.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD Sld7_C PF18596.1 EAU81391.2 - 0.18 12.0 0.2 8 6.7 0.0 2.6 2 0 0 2 2 2 0 Sld7 C-terminal domain AAA_23 PF13476.6 EAU81391.2 - 0.22 12.0 5.1 6.4 7.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain DUF1275 PF06912.11 EAU81392.2 - 1.5e-28 100.0 17.9 2.2e-28 99.5 17.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1275 PF06912.11 EAU81393.2 - 1.4e-18 67.5 12.2 5.1e-18 65.7 12.9 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1275) P5CR_dimer PF14748.6 EAU81394.2 - 0.012 15.9 0.0 0.065 13.5 0.0 2.1 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation Caps_assemb_Wzi PF14052.6 EAU81394.2 - 0.048 12.7 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Capsule assembly protein Wzi ATP1G1_PLM_MAT8 PF02038.16 EAU81394.2 - 5.4 6.5 4.8 1.1e+02 2.3 5.0 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Motile_Sperm PF00635.26 EAU81396.2 - 6.3e-16 58.2 0.0 8.9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Motile_Sperm PF00635.26 EAU81397.2 - 7.4e-17 61.2 0.0 9.4e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 EAU81397.2 - 0.084 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Trypan_PARP PF05887.11 EAU81400.1 - 3.3e-06 27.1 38.5 3.3e-06 27.1 38.5 7.5 6 2 2 8 8 8 1 Procyclic acidic repetitive protein (PARP) Borrelia_P83 PF05262.11 EAU81400.1 - 0.00051 18.7 1.1 0.00051 18.7 1.1 6.2 4 2 3 7 7 7 1 Borrelia P83/100 protein Drf_GBD PF06371.13 EAU81401.1 - 0.55 9.8 6.1 1.2 8.7 6.1 1.5 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain F-box PF00646.33 EAU81402.2 - 0.0077 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EAU81402.2 - 4 8.0 12.5 5 7.7 0.8 5.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 EAU81405.1 - 2.5e-05 24.6 1.0 1.2 9.6 0.1 4.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU81405.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EAU81405.1 - 0.017 14.9 0.1 14 5.5 0.1 3.2 2 0 0 2 2 2 0 Leucine rich repeat F-box PF00646.33 EAU81405.1 - 0.077 12.9 0.3 0.5 10.3 0.1 2.4 1 1 1 2 2 2 0 F-box domain Pyridoxal_deC PF00282.19 EAU81406.1 - 1.1e-64 218.5 0.0 1.5e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EAU81406.1 - 0.0038 16.2 0.0 0.0062 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V dCache_3 PF14827.6 EAU81406.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase DUF4309 PF14172.6 EAU81406.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) Ribosomal_L16 PF00252.18 EAU81407.1 - 2.1e-38 131.3 0.3 2.6e-38 131.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PRP3 PF08572.10 EAU81408.2 - 1.4e-69 234.3 8.1 1.4e-69 234.3 8.1 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EAU81408.2 - 7.7e-45 152.6 0.8 3e-44 150.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) WW PF00397.26 EAU81409.1 - 0.014 15.4 0.1 0.014 15.4 0.1 2.0 2 0 0 2 2 2 0 WW domain DUF4081 PF13312.6 EAU81410.2 - 0.31 11.3 1.8 0.85 9.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) adh_short PF00106.25 EAU81412.1 - 6.9e-16 58.3 0.0 8.7e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU81412.1 - 1.9e-10 40.7 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1424 PF07232.11 EAU81413.2 - 0.014 14.4 0.3 0.027 13.5 0.3 1.4 1 0 0 1 1 1 0 Putative rep protein (DUF1424) EF-hand_14 PF17959.1 EAU81413.2 - 0.018 15.3 0.1 0.046 14.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain DUF4449 PF14613.6 EAU81413.2 - 5.7 7.0 10.6 0.057 13.5 0.3 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4449) p450 PF00067.22 EAU81414.2 - 7.2e-55 186.6 0.0 1.4e-52 179.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ORC2 PF04084.14 EAU81415.2 - 3.9e-94 315.3 0.0 4.8e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Treacle PF03546.14 EAU81415.2 - 0.17 10.7 4.3 0.28 9.9 4.3 1.2 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle Ricin_B_lectin PF00652.22 EAU81416.1 - 2.9e-16 59.9 0.2 4.9e-16 59.1 0.2 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU81416.1 - 9.7e-10 39.1 0.6 2.5e-06 28.1 0.2 2.8 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_1 PF00232.18 EAU81417.2 - 9.2e-130 433.1 0.9 2.4e-129 431.7 0.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Mito_carr PF00153.27 EAU81419.2 - 1.8e-56 188.0 6.5 2.1e-21 75.7 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein His_Phos_2 PF00328.22 EAU81420.2 - 3.5e-19 69.4 0.0 2e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAM183 PF14886.6 EAU81421.1 - 0.095 13.4 0.2 0.12 13.1 0.2 1.3 1 0 0 1 1 1 0 FAM183A and FAM183B related DCP1 PF06058.13 EAU81422.1 - 2.2e-20 72.7 0.0 7.3e-20 71.0 0.0 1.8 1 1 0 1 1 1 1 Dcp1-like decapping family RAG2 PF03089.14 EAU81422.1 - 0.031 13.3 1.2 0.12 11.3 0.0 2.0 2 0 0 2 2 2 0 Recombination activating protein 2 F-box PF00646.33 EAU81423.1 - 1.6e-05 24.7 0.1 4.5e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU81423.1 - 0.0005 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU81423.1 - 0.003 17.9 0.4 7.4 7.1 0.1 3.9 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) Pmp3 PF01679.17 EAU81424.1 - 4.2e-17 62.1 7.9 5e-17 61.8 7.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UCH PF00443.29 EAU81425.1 - 4.9e-38 131.1 0.0 4.7e-35 121.3 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAU81425.1 - 2.1e-09 37.4 0.0 0.0026 17.4 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Jak1_Phl PF17887.1 EAU81425.1 - 2 8.4 5.7 13 5.8 1.6 2.6 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain F-box-like PF12937.7 EAU81426.2 - 8.5e-09 35.2 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU81426.2 - 8.2e-06 25.6 0.0 3.8e-05 23.4 0.0 2.3 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EAU81426.2 - 0.00044 20.6 0.1 1.7 9.2 0.0 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 EAU81426.2 - 0.034 14.0 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 F-box AMP-binding PF00501.28 EAU81427.2 - 2.8e-81 273.3 0.1 3.6e-79 266.3 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU81427.2 - 5.6e-11 43.3 0.0 1.5e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain tRNA-synt_1 PF00133.22 EAU81428.2 - 8.3e-149 496.6 0.0 1e-148 496.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAU81428.2 - 4.7e-18 65.6 0.0 1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAU81428.2 - 2.2e-17 62.9 0.0 3.3e-12 45.8 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 EAU81428.2 - 0.00068 19.4 6.5 0.0018 18.1 6.5 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 EAU81428.2 - 0.0024 17.3 0.0 0.89 8.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain LRR_4 PF12799.7 EAU81429.2 - 0.036 14.5 1.2 2.7 8.5 0.4 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU81429.2 - 0.064 13.2 1.2 0.28 11.1 0.1 2.5 2 0 0 2 2 2 0 F-box-like JUPITER PF17054.5 EAU81429.2 - 0.31 10.5 6.5 0.47 9.9 6.5 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter ProRS-C_1 PF09180.11 EAU81430.2 - 6.2e-29 100.0 0.6 1.3e-28 98.9 0.6 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EAU81430.2 - 3.3e-17 62.4 0.0 9.2e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.15 EAU81430.2 - 4.1e-16 59.2 0.1 7.3e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.25 EAU81430.2 - 4.4e-13 49.6 0.0 7.7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) THDPS_N_2 PF14805.6 EAU81430.2 - 0.09 13.0 0.1 0.28 11.4 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Bin3 PF06859.12 EAU81431.2 - 1.2e-36 125.7 0.0 1.7e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 EAU81431.2 - 0.0029 18.3 0.0 1.3 9.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EAU81431.2 - 0.038 14.6 0.0 5.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain SURF4 PF02077.15 EAU81432.1 - 1.2e-96 323.5 7.3 1.3e-96 323.3 7.3 1.0 1 0 0 1 1 1 1 SURF4 family SURF4 PF02077.15 EAU81433.1 - 1.5e-87 293.6 2.1 1.8e-87 293.4 2.1 1.0 1 0 0 1 1 1 1 SURF4 family Gti1_Pac2 PF09729.9 EAU81436.2 - 2e-22 80.2 5.1 1.2e-19 71.1 0.1 3.1 3 0 0 3 3 3 3 Gti1/Pac2 family DUF155 PF02582.14 EAU81437.2 - 8.2e-42 143.3 0.0 4e-41 141.0 0.0 2.1 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sec5 PF15469.6 EAU81438.2 - 2.6e-57 193.7 1.3 1.8e-56 190.9 0.3 2.7 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 EAU81438.2 - 0.0012 18.9 0.0 0.0058 16.7 0.0 2.3 1 0 0 1 1 1 1 Vps51/Vps67 Phasin_2 PF09361.10 EAU81438.2 - 0.13 12.5 4.2 1 9.7 0.1 3.4 3 0 0 3 3 3 0 Phasin protein CK2S PF15011.6 EAU81438.2 - 0.13 12.1 2.1 0.25 11.2 0.4 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate COG2 PF06148.11 EAU81438.2 - 1.8 8.7 5.4 1.7 8.7 0.0 3.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Mod_r PF07200.13 EAU81438.2 - 2.5 8.2 9.5 1.4 9.0 0.1 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SURF4 PF02077.15 EAU81440.1 - 1.3e-09 38.1 0.3 1.6e-09 37.8 0.3 1.1 1 0 0 1 1 1 1 SURF4 family NUC153 PF08159.12 EAU81442.1 - 1.1e-12 47.5 0.3 2e-12 46.7 0.3 1.4 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EAU81442.1 - 0.029 15.3 0.4 90 4.2 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat BUD22 PF09073.10 EAU81442.1 - 1 8.6 34.8 1.6 8.0 34.8 1.3 1 0 0 1 1 1 0 BUD22 ADH_N PF08240.12 EAU81443.2 - 8e-31 106.1 2.3 1.6e-30 105.2 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU81443.2 - 8.4e-10 38.7 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAU81443.2 - 2.2e-06 27.3 0.1 4.5e-05 23.0 0.0 2.7 1 1 1 2 2 2 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 EAU81443.2 - 0.04 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 EAU81443.2 - 0.058 14.5 0.0 0.25 12.4 0.0 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase HMG-CoA_red PF00368.18 EAU81445.1 - 3.4e-143 477.1 6.3 5e-143 476.6 6.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EAU81445.1 - 8e-10 38.8 0.3 0.0018 18.1 0.1 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Herpes_LMP1 PF05297.11 EAU81445.1 - 0.41 9.8 4.6 0.79 8.9 4.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ribosomal_L44 PF00935.19 EAU81446.2 - 6.2e-37 125.9 12.1 1e-36 125.2 12.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 EAU81446.2 - 0.018 15.3 1.0 0.035 14.4 1.0 1.4 1 0 0 1 1 1 0 Cathelicidin Acetyltransf_3 PF13302.7 EAU81447.2 - 2.7e-06 28.1 0.0 6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU81447.2 - 0.0051 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HEAT PF02985.22 EAU81450.2 - 0.0035 17.5 6.8 15 6.2 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EAU81450.2 - 0.04 14.3 12.9 0.78 10.2 0.3 5.8 5 1 1 6 6 6 0 HEAT repeats Nucleo_P87 PF07267.11 EAU81450.2 - 0.097 11.5 1.5 0.17 10.7 1.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 UNC45-central PF11701.8 EAU81450.2 - 0.21 11.6 1.4 2.4 8.1 0.0 3.3 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central Pox_Ag35 PF03286.14 EAU81450.2 - 0.3 10.9 7.7 0.57 10.0 6.4 2.2 3 0 0 3 3 3 0 Pox virus Ag35 surface protein COesterase PF00135.28 EAU81452.2 - 8e-57 193.3 0.0 6.9e-51 173.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU81452.2 - 0.0026 17.6 0.3 0.0064 16.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.10 EAU81452.2 - 0.057 12.5 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) SRP19 PF01922.17 EAU81453.2 - 3.4e-27 95.2 0.0 5.4e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein JTB PF05439.12 EAU81454.2 - 0.0001 22.3 0.0 0.00011 22.2 0.0 1.0 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) Glyco_hydro_18 PF00704.28 EAU81455.1 - 7.7e-61 206.5 0.0 9.2e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EAU81455.1 - 0.16 11.4 0.2 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 85 TPR_1 PF00515.28 EAU81456.1 - 1.1e-05 25.0 3.4 0.09 12.6 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAU81456.1 - 0.00016 21.5 5.8 0.1 12.8 1.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU81456.1 - 0.00076 19.5 1.1 0.023 14.9 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU81456.1 - 0.0027 18.0 3.6 0.0042 17.4 2.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU81456.1 - 0.0067 16.4 1.5 2.1 8.5 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ENT PF03735.14 EAU81456.1 - 0.02 14.9 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 ENT domain TPR_12 PF13424.6 EAU81456.1 - 0.047 14.0 4.0 4.1 7.8 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF859 PF05895.12 EAU81456.1 - 0.052 12.0 0.0 0.072 11.6 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) TPR_19 PF14559.6 EAU81456.1 - 0.081 13.4 1.2 0.081 13.4 1.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU81456.1 - 0.66 11.0 3.8 4.5 8.4 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAU81456.1 - 4.9 8.0 6.6 30 5.6 2.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.28 EAU81457.1 - 1.9e-12 47.9 0.0 3.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 SET domain HTH_21 PF13276.6 EAU81457.1 - 0.00074 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 HTH-like domain Herpes_capsid PF06112.11 EAU81457.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Myticin-prepro PF10690.9 EAU81457.1 - 0.15 12.3 3.7 6.9 7.0 1.0 2.4 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Glyco_hydro_18 PF00704.28 EAU81461.1 - 3.2e-59 201.2 0.0 3.8e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 EAU81461.1 - 0.0086 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_hydro_114 PF03537.13 EAU81461.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 BCNT PF07572.12 EAU81462.1 - 3.9e-20 71.7 0.1 7.3e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development DNA_pol_phi PF04931.13 EAU81462.1 - 1.2 7.2 11.3 1.6 6.7 11.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi PDCD2_C PF04194.13 EAU81462.1 - 1.6 8.8 6.6 4.3 7.4 6.6 1.6 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CDC45 PF02724.14 EAU81462.1 - 5.8 5.1 8.0 7 4.8 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DSPc PF00782.20 EAU81463.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EAU81463.1 - 0.011 15.9 0.1 0.056 13.6 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EAU81463.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family OPA3 PF07047.12 EAU81464.1 - 2.2e-45 153.4 0.2 3.2e-45 152.9 0.2 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FlxA PF14282.6 EAU81464.1 - 0.029 14.3 0.2 0.068 13.2 0.2 1.6 1 0 0 1 1 1 0 FlxA-like protein LPP PF04728.13 EAU81464.1 - 0.048 14.1 0.1 0.09 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper CHDCT2 PF08074.11 EAU81464.1 - 0.058 13.6 0.0 0.078 13.2 0.0 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Hemagglutinin PF00509.18 EAU81464.1 - 0.086 11.2 0.2 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Haemagglutinin Snf7 PF03357.21 EAU81464.1 - 0.1 12.2 0.8 3.2 7.3 0.1 2.1 2 0 0 2 2 2 0 Snf7 DUF3573 PF12097.8 EAU81464.1 - 0.2 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Alpha-L-AF_C PF06964.12 EAU81465.2 - 2.4e-21 76.6 0.3 1.2e-12 48.3 0.0 3.1 2 1 1 3 3 3 2 Alpha-L-arabinofuranosidase C-terminal domain CBM_6 PF03422.15 EAU81465.2 - 5e-05 23.6 1.4 5e-05 23.6 1.4 1.7 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) CBM_4_9 PF02018.17 EAU81465.2 - 0.0038 17.5 0.1 0.0083 16.4 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain Gmad2 PF10648.9 EAU81465.2 - 0.097 12.9 0.2 0.37 11.1 0.1 2.0 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination Ribosomal_S8 PF00410.19 EAU81466.2 - 4.5e-12 46.0 0.0 1.4e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 RicinB_lectin_2 PF14200.6 EAU81467.1 - 6.8e-18 65.2 13.2 1.4e-14 54.6 6.8 2.6 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU81467.1 - 4.3e-05 23.8 3.3 8.2e-05 22.9 0.5 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain FGF PF00167.18 EAU81467.1 - 0.084 13.0 0.0 0.57 10.3 0.0 2.2 1 1 1 2 2 2 0 Fibroblast growth factor RicinB_lectin_2 PF14200.6 EAU81468.2 - 2.3e-27 95.6 4.4 3.8e-15 56.4 0.1 2.3 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU81468.2 - 0.00088 19.5 0.6 0.027 14.7 1.0 2.1 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU81469.2 - 9.1e-16 58.4 2.8 1.4e-11 44.9 0.6 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU81469.2 - 0.00016 21.9 0.1 0.098 12.9 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain MatE PF01554.18 EAU81470.1 - 6.7e-53 178.6 24.4 3.9e-28 98.1 7.6 2.4 2 0 0 2 2 2 2 MatE DUF4577 PF15145.6 EAU81470.1 - 0.086 12.9 0.9 0.54 10.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4577) Bac_surface_Ag PF01103.23 EAU81471.1 - 9.7e-38 130.4 0.2 1.3e-37 130.0 0.2 1.2 1 0 0 1 1 1 1 Surface antigen ShlB PF03865.13 EAU81471.1 - 0.07 12.6 0.1 0.79 9.1 0.0 2.2 2 1 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Hist_deacetyl PF00850.19 EAU81472.2 - 5.1e-56 190.4 0.0 7e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RhgB_N PF09284.10 EAU81474.2 - 1.2e-103 346.0 0.8 1.8e-103 345.5 0.8 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EAU81474.2 - 2.9e-35 121.6 0.0 7.8e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EAU81474.2 - 2e-21 75.5 2.2 2e-21 75.5 2.2 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EAU81474.2 - 0.00017 21.8 3.0 0.0005 20.3 3.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EAU81474.2 - 0.02 14.9 0.1 0.06 13.4 0.1 1.8 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Cyclin_N PF00134.23 EAU81475.2 - 2e-41 140.7 0.3 6.4e-41 139.1 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAU81475.2 - 1.5e-24 86.3 0.0 3.3e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain p450 PF00067.22 EAU81476.2 - 3.6e-66 223.8 0.0 1.3e-65 221.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.26 EAU81477.1 - 9.4e-49 165.5 0.2 1.4e-48 164.9 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EAU81477.1 - 6.7e-14 51.0 0.3 6.7e-14 51.0 0.3 1.6 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NAD_Gly3P_dh_C PF07479.14 EAU81477.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Arm PF00514.23 EAU81478.1 - 4.5e-08 32.9 4.6 0.56 10.3 0.0 6.9 6 1 1 7 7 7 3 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EAU81478.1 - 0.0002 20.1 0.7 0.17 10.4 0.0 4.0 4 0 0 4 4 4 1 Adaptin N terminal region HEAT PF02985.22 EAU81478.1 - 0.0017 18.4 8.6 0.08 13.2 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat MMS19_C PF12460.8 EAU81478.1 - 0.027 13.6 0.6 4 6.4 0.0 3.6 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 EAU81478.1 - 0.074 13.4 17.6 3 8.3 0.1 7.6 8 1 0 8 8 8 0 HEAT repeats HEAT_EZ PF13513.6 EAU81478.1 - 0.97 10.0 6.2 36 5.0 0.0 6.4 7 1 1 8 8 8 0 HEAT-like repeat Ribosomal_L28e PF01778.17 EAU81481.2 - 5.2e-39 133.6 2.7 5.2e-39 133.6 2.7 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EAU81481.2 - 5.9e-28 97.4 17.0 5.9e-28 97.4 17.0 2.6 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EAU81481.2 - 2e-06 27.4 20.5 2.7e-06 27.0 20.5 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EAU81481.2 - 0.19 11.4 3.0 0.37 10.5 2.9 1.7 1 1 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 EAU81481.2 - 0.62 8.6 35.5 0.89 8.1 35.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.7 EAU81481.2 - 0.66 8.0 10.4 1 7.4 10.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 EAU81481.2 - 1.7 7.3 10.8 2.2 7.0 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRN3 PF05327.11 EAU81481.2 - 2.4 6.6 20.2 3.6 6.0 20.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EAU81481.2 - 6.4 4.9 38.2 9.1 4.3 38.2 1.1 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.14 EAU81481.2 - 8.7 6.8 43.8 2.8 8.5 15.8 2.4 1 1 1 2 2 2 0 Prothymosin/parathymosin family S1-P1_nuclease PF02265.16 EAU81483.1 - 5.2e-38 131.3 0.9 3.1e-34 118.9 0.2 3.1 2 1 0 2 2 2 2 S1/P1 Nuclease SH3_16 PF18348.1 EAU81483.1 - 0.049 13.4 0.4 0.14 12.0 0.0 2.0 3 0 0 3 3 3 0 Bacterial dipeptidyl-peptidase Sh3 domain Aminotran_1_2 PF00155.21 EAU81484.1 - 1.4e-50 172.5 0.0 1.8e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 EAU81486.2 - 4.8e-41 138.0 18.6 2.6e-11 43.9 1.5 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU81486.2 - 1.2e-15 57.6 3.6 0.0017 18.6 0.1 5.7 4 3 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU81486.2 - 1.2e-07 31.0 2.6 0.18 10.7 0.0 5.1 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 EAU81486.2 - 0.0002 20.2 2.2 0.087 11.6 0.1 2.8 2 2 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 EAU81486.2 - 0.00095 19.1 0.5 0.6 10.0 0.0 2.8 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EAU81486.2 - 0.0041 17.0 1.6 0.49 10.4 0.2 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 EAU81486.2 - 0.0098 15.8 1.5 0.79 9.6 0.1 2.5 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term Lactonase PF10282.9 EAU81486.2 - 0.03 13.6 0.0 7.2 5.8 0.0 2.9 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller IKI3 PF04762.12 EAU81486.2 - 0.13 10.2 3.5 6.5 4.6 0.7 2.9 2 1 0 2 2 2 0 IKI3 family DUF4082 PF13313.6 EAU81486.2 - 5.1 7.1 6.6 1.1 9.3 0.5 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4082) Snurportin1 PF11538.8 EAU81487.2 - 0.0008 19.5 6.7 0.0008 19.5 6.7 2.3 2 0 0 2 2 2 1 Snurportin1 DUF2408 PF10303.9 EAU81488.2 - 0.056 14.0 1.1 0.89 10.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF4510 PF14971.6 EAU81488.2 - 0.21 12.0 6.0 1.9 8.8 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4510) Sin3a_C PF16879.5 EAU81489.2 - 2.7e-81 273.4 1.2 5.5e-80 269.1 0.2 3.1 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EAU81489.2 - 6.3e-38 128.8 0.5 2e-37 127.2 0.5 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor 2-Hacid_dh_C PF02826.19 EAU81489.2 - 4e-37 127.3 0.0 7.4e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAH PF02671.21 EAU81489.2 - 4.5e-34 116.3 11.0 3e-19 68.9 0.2 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat 2-Hacid_dh PF00389.30 EAU81489.2 - 1.6e-25 89.3 0.0 3.4e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 EAU81489.2 - 0.033 14.8 0.0 0.11 13.1 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cyclin_N PF00134.23 EAU81490.1 - 3.4e-45 152.9 1.2 7.9e-45 151.7 0.5 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAU81490.1 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_S15 PF00312.22 EAU81491.1 - 5.7e-21 74.5 1.4 9.5e-21 73.8 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 Mlh1_C PF16413.5 EAU81492.2 - 1.4e-95 319.7 0.0 2.7e-95 318.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EAU81492.2 - 8.9e-30 102.8 0.1 1.7e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EAU81492.2 - 5.4e-13 48.9 0.2 3.1e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAU81492.2 - 1.8e-07 31.6 0.0 4.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOR2-PAG1_N PF14222.6 EAU81493.2 - 9.4e-164 546.4 0.3 8.9e-163 543.2 0.0 2.4 3 0 0 3 3 3 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EAU81493.2 - 2.1e-90 303.0 2.2 2.1e-90 303.0 2.2 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EAU81493.2 - 7.5e-13 47.1 2.1 1.2e-08 33.2 0.2 3.0 3 0 0 3 3 3 2 Cell morphogenesis central region Nipped-B_C PF12830.7 EAU81493.2 - 0.057 13.4 0.4 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus CENP-B_dimeris PF09026.10 EAU81493.2 - 0.72 10.3 6.8 2.2 8.7 6.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RPN1_RPN2_N PF17781.1 EAU81494.2 - 2.1e-106 355.8 0.0 3.2e-106 355.2 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EAU81494.2 - 2.3e-30 104.4 0.1 4.3e-30 103.5 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EAU81494.2 - 7.5e-20 70.3 26.6 2.6e-05 24.4 0.5 8.6 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EAU81494.2 - 6.2e-06 26.5 0.2 0.28 11.6 0.0 4.5 5 0 0 5 5 5 2 HEAT repeats THOC2_N PF16134.5 EAU81494.2 - 0.024 13.3 0.0 0.048 12.3 0.0 1.4 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Adaptin_N PF01602.20 EAU81494.2 - 0.034 12.7 0.0 0.22 10.0 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Phage_TAC_11 PF11836.8 EAU81494.2 - 0.3 11.3 1.6 3.9 7.7 0.2 3.0 2 0 0 2 2 2 0 Phage tail tube protein, GTA-gp10 UPF0242 PF06785.11 EAU81494.2 - 0.51 10.4 4.7 1.4 9.0 4.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CBS PF00571.28 EAU81495.1 - 2e-07 31.3 0.0 8.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 CBS domain Adaptin_binding PF10199.9 EAU81502.2 - 0.0032 18.1 15.3 0.082 13.5 0.1 2.8 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Roughex PF06020.11 EAU81502.2 - 1.2 8.1 14.9 2.3 7.3 14.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein NPR3 PF03666.13 EAU81502.2 - 1.3 7.7 8.3 1.9 7.2 8.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 EAU81502.2 - 2.2 7.6 8.6 3.7 6.8 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PPP4R2 PF09184.11 EAU81502.2 - 2.3 7.7 19.0 4.9 6.7 19.0 1.6 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 EAU81502.2 - 2.6 6.3 18.5 3.6 5.8 18.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EAU81502.2 - 2.7 6.1 26.8 4.2 5.5 26.8 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 EAU81502.2 - 3.5 7.4 14.6 6.5 6.5 14.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF2457 PF10446.9 EAU81502.2 - 3.6 6.6 34.5 7.9 5.5 34.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 EAU81502.2 - 5.3 6.4 28.3 11 5.4 28.3 1.5 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EAU81502.2 - 9 6.0 23.3 23 4.6 23.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Toxin-JAB1 PF15659.6 EAU81504.2 - 0.077 13.3 1.3 2.3 8.6 0.1 2.6 2 0 0 2 2 2 0 JAB-like toxin 1 F-box-like PF12937.7 EAU81505.2 - 1.4e-05 24.9 6.6 3.4e-05 23.6 6.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU81505.2 - 0.03 14.2 3.3 0.093 12.6 3.3 1.9 1 0 0 1 1 1 0 F-box domain CEP63 PF17045.5 EAU81505.2 - 0.23 11.3 0.9 0.34 10.8 0.9 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF5446 PF17522.2 EAU81505.2 - 0.28 11.4 1.4 0.53 10.5 1.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5446) RRM_1 PF00076.22 EAU81508.2 - 2.8e-17 62.3 0.0 2.1e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Orbi_VP6 PF01516.16 EAU81508.2 - 2.8 7.4 7.3 5.5 6.4 7.3 1.4 1 0 0 1 1 1 0 Orbivirus helicase VP6 APH PF01636.23 EAU81509.2 - 4.5e-12 46.4 0.0 2.4e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family SDP_N PF12278.8 EAU81509.2 - 0.44 10.7 1.8 1.1 9.4 1.8 1.6 1 0 0 1 1 1 0 Sex determination protein N terminal Metallophos PF00149.28 EAU81511.2 - 3e-18 67.1 0.8 4.9e-18 66.4 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_carr PF00153.27 EAU81512.2 - 6.1e-53 176.7 1.2 4.3e-19 68.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAU81512.2 - 0.093 11.9 0.2 14 4.8 0.1 2.5 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Methyltr_RsmB-F PF01189.17 EAU81513.1 - 3.3e-35 121.6 0.0 5e-34 117.7 0.0 2.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EAU81513.1 - 0.059 13.9 0.0 0.17 12.4 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EAU81513.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase LRR_4 PF12799.7 EAU81514.1 - 0.051 14.0 13.9 4.5 7.8 0.1 5.4 5 3 0 5 5 5 0 Leucine Rich repeats (2 copies) Pmp3 PF01679.17 EAU81515.1 - 1.3e-23 82.9 10.6 1.5e-23 82.7 10.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.11 EAU81515.1 - 0.00012 22.4 1.0 0.00014 22.1 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1056) Kinetochor_Ybp2 PF08568.10 EAU81517.1 - 2.7e-20 72.4 0.8 6.4e-19 67.9 0.1 2.3 1 1 2 3 3 3 2 Uncharacterised protein family, YAP/Alf4/glomulin F-box-like PF12937.7 EAU81523.1 - 0.0032 17.3 0.3 0.0032 17.3 0.3 2.4 3 0 0 3 3 3 1 F-box-like CH PF00307.31 EAU81525.2 - 6.7e-74 245.1 0.0 2.2e-20 72.9 0.0 4.6 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EAU81525.2 - 0.0002 21.1 0.0 8.3 6.3 0.0 3.7 3 0 0 3 3 3 3 CAMSAP CH domain EF-hand_7 PF13499.6 EAU81525.2 - 0.0035 17.8 0.0 0.014 15.9 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair Complex1_49kDa PF00346.19 EAU81525.2 - 0.085 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit CH_2 PF06294.11 EAU81525.2 - 0.12 12.5 0.1 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 CH-like domain in sperm protein OPT PF03169.15 EAU81526.2 - 1.4e-171 572.3 59.3 2.3e-171 571.5 59.3 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Helitron_like_N PF14214.6 EAU81530.1 - 3e-06 27.6 0.0 4.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus p450 PF00067.22 EAU81537.2 - 1.7e-14 53.4 0.0 2.8e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 EAU81538.2 - 3.3e-47 159.0 0.2 1.3e-12 48.2 0.0 5.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU81538.2 - 1e-38 126.9 4.8 4.1e-05 23.6 0.0 9.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 EAU81538.2 - 1.6e-35 121.0 9.8 5.6e-08 33.2 0.7 8.5 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU81538.2 - 5.9e-35 118.9 14.5 7.4e-11 42.1 0.2 7.3 2 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU81538.2 - 1.3e-33 114.0 11.2 2.3e-05 24.6 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat NACHT PF05729.12 EAU81538.2 - 2.2e-05 24.4 0.0 5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EAU81538.2 - 0.00085 18.6 0.0 0.0018 17.5 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain NapD PF03927.13 EAU81538.2 - 0.004 17.2 0.3 8.6 6.5 0.0 3.6 3 1 1 4 4 3 2 NapD protein AAA_16 PF13191.6 EAU81538.2 - 0.035 14.5 0.0 0.17 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 EAU81538.2 - 0.062 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EAU81538.2 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Acetyltransf_3 PF13302.7 EAU81539.1 - 3.3e-11 44.0 0.0 4.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU81539.1 - 0.013 15.7 0.0 6.2 7.1 0.0 2.4 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family SEP PF08059.13 EAU81540.2 - 1.2e-20 73.9 0.0 2.7e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EAU81540.2 - 2.1e-16 59.9 0.1 3.7e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 UBX domain Acetyltransf_3 PF13302.7 EAU81541.1 - 2.6e-10 41.1 0.0 7.9e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU81541.1 - 0.14 12.4 0.0 23 5.2 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Diphthamide_syn PF01866.17 EAU81544.2 - 8.7e-86 288.1 0.1 4.9e-53 180.5 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Aldo_ket_red PF00248.21 EAU81547.1 - 3.2e-72 243.2 0.0 4.1e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TetR_C_10 PF16295.5 EAU81547.1 - 0.14 12.4 0.3 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cpn60_TCP1 PF00118.24 EAU81548.1 - 1.6e-83 281.0 7.5 2.7e-83 280.3 7.5 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rubella_E2 PF05749.11 EAU81548.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 RNase_II_C_S1 PF18614.1 EAU81549.2 - 0.089 12.8 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain Polysacc_deac_1 PF01522.21 EAU81555.2 - 4.2e-23 81.6 0.0 6.8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Cys_Met_Meta_PP PF01053.20 EAU81556.1 - 1.7e-105 352.7 0.0 2.8e-80 269.7 0.0 2.7 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EAU81556.1 - 0.00084 18.6 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EAU81556.1 - 0.14 10.6 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase DUF5533 PF17685.1 EAU81557.1 - 0.084 13.3 0.1 0.19 12.1 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5533) PsiA PF06952.11 EAU81557.1 - 0.19 11.0 0.6 5.4 6.2 0.1 2.1 2 0 0 2 2 2 0 PsiA protein Pro_isomerase PF00160.21 EAU81559.1 - 1.6e-49 168.2 0.0 2.5e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CHRD PF07452.12 EAU81559.1 - 0.085 13.8 2.6 0.23 12.4 2.6 1.9 1 1 0 1 1 1 0 CHRD domain AJAP1_PANP_C PF15298.6 EAU81559.1 - 0.44 10.7 4.4 0.68 10.1 4.4 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus SelP_N PF04592.14 EAU81562.1 - 2.6 7.4 15.9 3.8 6.8 15.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Asp4 PF16996.5 EAU81563.2 - 0.39 10.5 1.0 0.89 9.4 1.0 1.6 1 1 0 1 1 1 0 Accessory secretory protein Sec Asp4 polyprenyl_synt PF00348.17 EAU81564.1 - 3.3e-84 282.0 0.0 3.5e-83 278.6 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase Metal_resist PF13801.6 EAU81564.1 - 0.0092 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal resistance DUF347 PF03988.12 EAU81567.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 EAU81567.1 - 0.087 13.7 0.7 0.17 12.8 0.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rpr2 PF04032.16 EAU81568.2 - 0.005 17.1 1.7 0.018 15.3 1.7 2.0 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain FAR1 PF03101.15 EAU81568.2 - 0.0071 17.0 0.2 0.025 15.3 0.2 1.9 1 0 0 1 1 1 1 FAR1 DNA-binding domain COX7C PF02935.16 EAU81571.2 - 2.4e-14 53.3 3.3 2.8e-14 53.1 3.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc COX7C PF02935.16 EAU81572.1 - 2e-12 47.2 2.6 2.3e-12 47.0 2.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc FA_desaturase PF00487.24 EAU81573.1 - 2e-25 90.1 25.8 3.4e-25 89.4 25.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EAU81573.1 - 0.0019 18.4 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 EAU81574.2 - 8.9e-28 97.8 26.3 1.5e-27 97.1 26.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EAU81574.2 - 0.0042 17.3 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) PI3K_1B_p101 PF10486.9 EAU81575.1 - 1.1 6.9 2.4 1.4 6.6 2.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit BolA PF01722.18 EAU81577.2 - 1.6e-18 66.7 0.1 4.1e-18 65.4 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein ATP-grasp_3 PF02655.14 EAU81578.2 - 5.6e-10 39.5 0.0 9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 EAU81578.2 - 0.031 13.5 0.0 0.43 9.8 0.0 2.1 1 1 1 2 2 2 0 YheC/D like ATP-grasp DJ-1_PfpI PF01965.24 EAU81579.1 - 6.8e-18 65.0 0.0 1e-17 64.4 0.0 1.3 1 1 0 1 1 1 1 DJ-1/PfpI family BTB PF00651.31 EAU81580.2 - 0.0017 18.6 0.0 0.0041 17.3 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Ricin_B_lectin PF00652.22 EAU81581.1 - 3.8e-18 66.0 9.7 3.8e-18 66.0 9.7 1.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU81581.1 - 9e-08 32.7 12.4 1.1e-05 26.0 3.6 3.4 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like ET PF01684.16 EAU81581.1 - 0.044 14.1 0.9 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 ET module Methyltransf_16 PF10294.9 EAU81582.2 - 2.8e-19 69.5 0.0 3.4e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EAU81582.2 - 0.0025 17.6 0.0 0.0033 17.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU81582.2 - 0.038 14.7 0.0 0.094 13.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EAU81582.2 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cu_bind_like PF02298.17 EAU81583.2 - 6.7e-05 22.8 1.0 0.0054 16.7 0.1 2.9 2 1 0 2 2 2 2 Plastocyanin-like domain Kelch_3 PF13415.6 EAU81585.2 - 1.4e-24 85.8 9.4 7.2e-08 32.5 0.0 5.3 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF4110 PF13422.6 EAU81585.2 - 6.4e-21 74.2 0.7 6.4e-21 74.2 0.7 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EAU81585.2 - 1.8e-18 66.3 12.6 1.8e-06 27.9 0.1 5.4 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EAU81585.2 - 3.1e-15 55.8 3.0 1.1e-06 28.7 0.0 3.8 2 1 1 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EAU81585.2 - 2.8e-12 46.0 5.7 4.4e-06 26.2 0.1 4.0 3 1 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EAU81585.2 - 1.2e-09 37.7 10.3 2.9e-06 27.0 0.1 3.8 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EAU81585.2 - 2.8e-09 36.8 7.7 8.7e-05 22.4 0.1 4.2 5 0 0 5 5 5 2 Kelch motif Glyco_hydro_16 PF00722.21 EAU81587.2 - 6e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 EAU81588.1 - 3.7e-05 23.3 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 EAU81589.2 - 6.5e-05 22.5 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Pkinase_fungal PF17667.1 EAU81592.2 - 2.1e-43 148.6 0.0 7.2e-43 146.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU81592.2 - 0.00024 20.5 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU81592.2 - 0.0083 16.1 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAU81592.2 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU81593.2 - 2.9e-24 85.6 0.0 4.3e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PIN_4 PF13638.6 EAU81595.1 - 5.1e-07 30.0 0.0 8.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 PIN domain DUF2325 PF10087.9 EAU81595.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) NB-LRR PF12061.8 EAU81595.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 Pkinase_fungal PF17667.1 EAU81596.2 - 1.4e-46 159.1 0.0 1.2e-45 156.0 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase SARAF PF06682.12 EAU81597.2 - 0.012 15.3 0.0 0.05 13.2 0.0 2.1 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Shisa PF13908.6 EAU81597.2 - 0.35 11.1 1.3 3.1 8.0 0.0 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Vpu PF00558.19 EAU81597.2 - 3.6 7.4 5.7 21 5.0 0.2 3.4 4 0 0 4 4 4 0 Vpu protein MAD PF05557.13 EAU81598.1 - 4.2e-46 157.6 74.1 7.3e-46 156.8 74.1 1.3 1 1 0 1 1 1 1 Mitotic checkpoint protein UPF0242 PF06785.11 EAU81598.1 - 0.00022 21.4 18.1 0.00022 21.4 18.1 6.1 2 1 3 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus MPS2 PF17060.5 EAU81598.1 - 0.018 14.3 0.6 0.018 14.3 0.6 5.9 2 1 4 7 7 7 0 Monopolar spindle protein 2 ATP-grasp_3 PF02655.14 EAU81598.1 - 0.043 13.9 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain NRN1 PF15056.6 EAU81598.1 - 0.071 13.2 0.4 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 Neuritin protein family Fib_alpha PF08702.10 EAU81598.1 - 0.42 10.8 46.9 0.069 13.3 4.6 6.3 4 1 2 7 7 7 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 EAU81598.1 - 2.7 7.7 29.1 1.5 8.5 1.6 4.9 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain YL1 PF05764.13 EAU81599.2 - 0.0014 18.8 0.6 0.0021 18.2 0.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Ribosomal_60s PF00428.19 EAU81599.2 - 0.2 12.2 4.6 0.087 13.4 1.7 1.9 1 1 1 2 2 2 0 60s Acidic ribosomal protein Lactamase_B_2 PF12706.7 EAU81600.1 - 1.4e-34 119.4 0.0 2.4e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAU81600.1 - 8.3e-09 35.5 0.0 2e-05 24.6 0.0 3.0 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Hol_Tox PF16935.5 EAU81600.1 - 0.043 13.9 0.0 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative Holin-like Toxin (Hol-Tox) Lactamase_B PF00753.27 EAU81600.1 - 0.088 12.8 4.1 0.28 11.2 2.4 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily GTP_EFTU PF00009.27 EAU81604.2 - 3.5e-51 173.5 0.0 5e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAU81604.2 - 8e-18 64.3 0.3 3.5e-17 62.2 0.1 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAU81604.2 - 6.8e-09 36.0 1.5 1.8e-08 34.7 1.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAU81604.2 - 6e-07 29.5 0.1 2.3e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAU81604.2 - 0.041 13.3 0.1 2.8 7.3 0.1 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TTRAP PF14203.6 EAU81604.2 - 0.12 12.4 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein FeoB_N PF02421.18 EAU81604.2 - 0.12 11.9 0.0 1.2 8.6 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAU81604.2 - 0.16 11.9 0.1 1.6 8.6 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Pkinase_fungal PF17667.1 EAU81605.2 - 2.2e-50 171.6 0.0 3.1e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU81605.2 - 5.1e-08 32.6 0.0 8.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU81605.2 - 0.017 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 EAU81606.1 - 5.9e-14 52.4 0.0 3.5e-11 43.5 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU81606.1 - 1.4e-09 37.4 0.1 0.012 16.1 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EAU81606.1 - 2.1e-09 37.7 0.2 2.6e-05 24.7 0.0 4.4 3 2 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EAU81606.1 - 6.7e-08 32.6 0.5 0.028 14.9 0.2 4.3 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAU81606.1 - 1.9e-07 31.2 1.4 0.00071 19.8 0.2 3.6 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Pdase_M17_N2 PF18295.1 EAU81607.2 - 0.00042 20.6 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 2 M17 aminopeptidase N-terminal domain 2 Glyco_hydro_88 PF07470.13 EAU81609.2 - 1.7e-16 60.2 0.5 2.4e-16 59.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 F-box-like PF12937.7 EAU81610.1 - 9.3e-12 44.7 1.4 2.1e-11 43.5 1.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU81610.1 - 0.038 13.9 1.1 0.46 10.4 1.1 2.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 EAU81611.1 - 0.00012 21.9 0.4 0.00025 20.9 0.4 1.6 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.26 EAU81612.2 - 1e-11 44.6 8.5 5.5e-07 29.7 0.9 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU81612.2 - 3.3e-07 30.6 6.4 6.1e-05 23.5 0.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU81612.2 - 5.6e-06 26.5 11.9 0.00017 21.8 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EAU81612.2 - 6.3e-05 22.9 1.4 0.00018 21.4 0.4 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 EAU81612.2 - 0.0065 16.8 3.4 0.15 12.5 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAU81612.2 - 0.009 16.3 2.8 0.73 10.2 0.0 2.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EAU81612.2 - 0.038 14.3 0.3 0.069 13.5 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SPX PF03105.19 EAU81612.2 - 2 8.2 5.7 2.6 7.9 5.7 1.1 1 0 0 1 1 1 0 SPX domain Sugar_tr PF00083.24 EAU81614.1 - 2.7e-94 316.6 21.8 3.1e-94 316.4 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU81614.1 - 7.4e-18 64.6 39.7 1.7e-11 43.7 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HA2 PF04408.23 EAU81615.1 - 1.2e-23 83.4 0.0 2.6e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAU81615.1 - 5.5e-22 77.9 0.0 4.7e-21 74.9 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAU81615.1 - 4.2e-10 39.9 0.0 2.4e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU81615.1 - 1.6e-08 34.6 0.2 3.2e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.22 EAU81615.1 - 0.0001 22.0 0.4 0.00044 19.9 0.4 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 EAU81615.1 - 0.00018 21.8 0.0 0.00053 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU81615.1 - 0.00082 19.7 0.3 0.0019 18.5 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU81615.1 - 0.0049 16.6 0.1 0.0084 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAU81615.1 - 0.0083 15.2 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 EAU81615.1 - 0.013 15.5 0.1 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EAU81615.1 - 0.036 13.6 0.2 0.24 10.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAU81615.1 - 0.042 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 EAU81615.1 - 0.053 13.0 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Flavi_DEAD PF07652.14 EAU81615.1 - 0.057 13.4 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 EAU81615.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EAU81615.1 - 0.071 12.4 0.1 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EAU81615.1 - 0.09 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 EAU81616.1 - 5.6e-60 203.1 0.0 1.2e-59 202.0 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DnaJ-X PF14308.6 EAU81617.2 - 4.8e-54 183.0 0.0 4.8e-54 183.0 0.0 2.6 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EAU81617.2 - 2e-25 88.7 0.2 5.2e-25 87.4 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain Rtf2 PF04641.12 EAU81617.2 - 0.028 13.8 0.7 0.061 12.7 0.7 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger Casc1_N PF15927.5 EAU81617.2 - 0.18 11.5 8.4 0.059 13.1 3.9 2.3 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF1441 PF07278.11 EAU81617.2 - 0.37 10.7 2.9 1.4 8.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) DUF2058 PF09831.9 EAU81617.2 - 0.47 10.6 7.6 1.1 9.5 7.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) PEX11 PF05648.14 EAU81617.2 - 1.4 8.4 3.1 0.73 9.3 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2514 PF10721.9 EAU81617.2 - 2.3 8.2 8.0 3.4 7.7 6.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) MMR_HSR1 PF01926.23 EAU81619.1 - 4e-10 39.8 0.0 8.2e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU81619.1 - 1.3e-09 37.7 0.0 1.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 EAU81619.1 - 2.5e-07 30.9 0.0 7.4e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU81619.1 - 6.3e-07 29.1 0.0 2.7e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Ras family RsgA_GTPase PF03193.16 EAU81619.1 - 4.2e-06 26.8 0.0 8.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EAU81619.1 - 5.8e-05 23.5 0.1 0.00014 22.3 0.1 1.6 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EAU81619.1 - 0.00027 21.5 0.0 0.00054 20.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 EAU81619.1 - 0.001 19.1 0.1 0.02 15.0 0.1 2.3 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.6 EAU81619.1 - 0.0019 18.5 0.0 0.0039 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAU81619.1 - 0.0023 17.2 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EAU81619.1 - 0.003 17.9 0.0 0.0056 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase IIGP PF05049.13 EAU81619.1 - 0.0031 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Arf PF00025.21 EAU81619.1 - 0.013 15.0 0.0 0.11 12.0 0.0 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.10 EAU81619.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EAU81619.1 - 0.024 14.1 0.0 0.08 12.5 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Guanylate_kin PF00625.21 EAU81619.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase AAA_7 PF12775.7 EAU81619.1 - 0.035 13.6 0.0 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 EAU81619.1 - 0.075 12.8 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA PF00004.29 EAU81619.1 - 0.081 13.4 0.0 0.73 10.3 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAU81619.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 EAU81619.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.2 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 EAU81620.2 - 5e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU81620.2 - 0.00035 20.0 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EAU81620.2 - 0.00038 20.4 0.3 0.001 19.0 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EAU81620.2 - 0.0023 18.3 0.0 0.0057 17.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 EAU81620.2 - 0.011 16.0 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EAU81620.2 - 0.013 16.1 0.1 0.03 14.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Ras PF00071.22 EAU81620.2 - 0.021 14.4 0.2 0.57 9.8 0.2 2.5 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 EAU81620.2 - 0.06 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAU81620.2 - 0.072 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EAU81620.2 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EAU81620.2 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EAU81620.2 - 0.21 12.1 0.9 0.38 11.2 0.7 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EAU81622.1 - 1e-112 376.1 0.4 1.4e-112 375.6 0.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EAU81622.1 - 8.6e-08 32.3 0.0 2.3e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU81622.1 - 1.7e-07 31.3 0.8 4.1e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EAU81622.1 - 5.7e-06 26.0 1.5 0.00067 19.2 0.0 2.7 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EAU81622.1 - 0.00021 21.5 0.0 0.00046 20.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EAU81622.1 - 0.00064 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 EAU81622.1 - 0.00073 19.8 1.9 0.0038 17.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU81622.1 - 0.0016 18.9 0.1 0.0066 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 EAU81622.1 - 0.0018 17.9 0.2 0.0073 15.9 0.2 2.0 1 1 0 1 1 1 1 Ras family PduV-EutP PF10662.9 EAU81622.1 - 0.0038 17.0 0.3 0.15 11.8 0.1 2.5 1 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EAU81622.1 - 0.0067 16.0 0.1 0.013 15.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 EAU81622.1 - 0.0069 16.9 0.1 0.018 15.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 EAU81622.1 - 0.02 15.0 0.5 0.055 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAU81622.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EAU81622.1 - 0.05 13.2 0.4 0.13 11.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAU81622.1 - 0.065 12.9 0.2 0.065 12.9 0.2 1.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EAU81622.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Dynamin_N PF00350.23 EAU81622.1 - 0.074 13.1 5.8 1.2 9.1 0.1 3.0 2 1 1 3 3 3 0 Dynamin family Sigma54_activat PF00158.26 EAU81622.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 EAU81622.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 EAU81622.1 - 0.16 11.5 0.2 0.57 9.7 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B F-box-like PF12937.7 EAU81623.1 - 1e-05 25.3 8.9 1.6e-05 24.7 3.5 3.3 3 1 0 3 3 3 1 F-box-like NIF PF03031.18 EAU81625.2 - 1.7e-16 60.3 0.0 3e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Adaptin_binding PF10199.9 EAU81625.2 - 0.0088 16.6 1.9 0.017 15.7 1.9 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 HSP90 PF00183.18 EAU81625.2 - 8.4 5.2 7.7 15 4.3 7.7 1.3 1 0 0 1 1 1 0 Hsp90 protein DUF3337 PF11816.8 EAU81628.2 - 1.4e-39 135.8 0.6 3.5e-39 134.4 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EAU81628.2 - 1.2e-20 73.4 20.4 1.7e-05 25.4 0.3 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat RAWUL PF16207.5 EAU81628.2 - 0.0035 18.0 0.0 0.0071 17.0 0.0 1.5 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like ANAPC4_WD40 PF12894.7 EAU81628.2 - 0.012 15.9 0.0 0.052 13.8 0.0 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU81628.2 - 0.034 13.1 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M48 PF01435.18 EAU81629.1 - 2.2e-26 92.8 0.1 8.3e-26 91.0 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 EAU81629.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) NAD_binding_9 PF13454.6 EAU81630.1 - 3.1e-05 24.0 0.0 0.00012 22.1 0.0 2.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAU81630.1 - 0.00019 20.8 0.0 0.21 10.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU81630.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF1996 PF09362.10 EAU81631.2 - 2.3e-61 207.8 0.1 3e-61 207.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HNH PF01844.23 EAU81632.1 - 0.0017 18.5 1.2 0.0046 17.1 1.2 1.7 1 1 0 1 1 1 1 HNH endonuclease C1_1 PF00130.22 EAU81632.1 - 0.044 13.7 0.6 0.13 12.1 0.6 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Phage_int_SAM_3 PF14659.6 EAU81632.1 - 0.078 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HNH_5 PF14279.6 EAU81632.1 - 0.71 9.8 2.4 11 6.0 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease CybS PF05328.12 EAU81634.1 - 5.6e-42 142.6 0.0 7.1e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit TPPK_C PF12555.8 EAU81634.1 - 0.076 13.1 3.1 0.25 11.4 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Dynamin_M PF01031.20 EAU81635.1 - 1e-27 97.1 0.3 1.6e-27 96.5 0.3 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EAU81635.1 - 2.6e-22 79.6 0.0 9e-22 77.9 0.0 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 EAU81635.1 - 5.2e-10 39.4 0.2 1.7e-09 37.7 0.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAU81635.1 - 1.2e-05 25.3 0.2 0.0004 20.4 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU81635.1 - 0.0043 16.4 0.0 0.44 9.8 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 EAU81635.1 - 0.059 12.9 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EAU81635.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 EAU81635.1 - 0.2 11.3 0.2 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 EF hand Ank_2 PF12796.7 EAU81638.2 - 1.4e-145 474.2 0.0 9.1e-20 71.0 0.0 11.4 1 1 11 12 12 12 11 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU81638.2 - 1.1e-107 350.7 45.2 2.2e-09 37.4 0.0 16.8 1 1 17 18 18 18 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU81638.2 - 9.5e-106 332.8 0.6 1.8e-05 24.8 0.0 20.1 19 0 0 19 19 19 18 Ankyrin repeat Ank_4 PF13637.6 EAU81638.2 - 9.3e-101 329.0 0.2 8e-11 42.3 0.0 17.4 1 1 16 18 18 18 18 Ankyrin repeats (many copies) Ank PF00023.30 EAU81638.2 - 2e-94 306.3 0.1 0.00044 20.6 0.0 19.7 19 0 0 19 19 19 18 Ankyrin repeat NapD PF03927.13 EAU81638.2 - 1.2e-10 41.2 31.9 0.11 12.5 0.2 15.7 9 4 11 20 20 19 2 NapD protein NACHT PF05729.12 EAU81638.2 - 3.4e-06 27.1 0.1 1.1e-05 25.5 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAU81638.2 - 0.0002 21.6 0.1 0.0011 19.2 0.1 2.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EAU81638.2 - 0.00083 19.3 2.9 0.73 9.7 0.0 5.3 5 1 0 5 5 5 1 NTPase IF2_N PF04760.15 EAU81638.2 - 0.0035 17.1 0.0 1.3e+02 2.5 0.0 7.7 12 0 0 12 12 11 0 Translation initiation factor IF-2, N-terminal region MeaB PF03308.16 EAU81638.2 - 0.0046 16.0 0.0 0.012 14.6 0.0 1.7 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EAU81638.2 - 0.0083 16.5 0.1 0.058 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EAU81638.2 - 0.0094 15.2 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF108 PF01958.18 EAU81638.2 - 0.011 16.1 15.8 63 4.0 0.1 9.3 4 4 7 11 11 11 0 Domain of unknown function DUF108 UPF0146 PF03686.13 EAU81638.2 - 0.044 13.7 15.5 1.4e+02 2.4 0.0 9.3 2 2 12 14 14 14 0 Uncharacterised protein family (UPF0146) AAA_14 PF13173.6 EAU81638.2 - 0.046 13.8 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAU81638.2 - 0.053 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2150 PF09920.9 EAU81638.2 - 0.096 12.7 0.8 0.24 11.4 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) E3_binding PF02817.17 EAU81638.2 - 4.1 7.8 32.2 26 5.2 0.0 12.0 15 0 0 15 15 14 0 e3 binding domain Alba PF01918.21 EAU81639.2 - 9.5e-05 22.1 0.9 0.11 12.3 0.1 3.1 3 1 0 3 3 3 2 Alba Peptidase_C12 PF01088.21 EAU81640.1 - 2.9e-49 167.7 0.0 4.8e-49 167.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-ZPR1 PF03367.13 EAU81641.2 - 1.8e-112 372.4 0.1 2.4e-55 186.7 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EAU81641.2 - 0.0051 16.8 1.5 1.2 9.1 0.1 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2688 PF10892.8 EAU81641.2 - 0.014 14.9 1.0 0.34 10.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) FpoO PF10621.9 EAU81641.2 - 0.099 13.0 0.2 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO DZR PF12773.7 EAU81641.2 - 0.3 11.1 4.7 2 8.5 0.1 2.9 2 1 0 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EAU81641.2 - 0.32 11.1 5.3 3.9 7.7 0.2 3.2 3 0 0 3 3 3 0 Zinc ribbon domain DUF983 PF06170.12 EAU81641.2 - 0.62 10.5 1.6 45 4.6 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF983) Rubredoxin_2 PF18073.1 EAU81641.2 - 2.8 7.7 10.5 4.2 7.2 0.6 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain Abhydrolase_3 PF07859.13 EAU81642.2 - 1.7e-14 54.2 0.0 2.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU81642.2 - 3.7e-13 49.1 0.0 6e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase RVT_3 PF13456.6 EAU81643.1 - 7.8e-05 22.5 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like Tup_N PF08581.10 EAU81643.1 - 0.0051 17.1 4.2 0.0095 16.2 4.2 1.3 1 0 0 1 1 1 1 Tup N-terminal Golgin_A5 PF09787.9 EAU81643.1 - 0.038 13.4 1.8 0.064 12.7 1.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 NAM-associated PF14303.6 EAU81648.1 - 0.043 14.5 1.9 0.055 14.2 1.9 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FAM199X PF15814.5 EAU81648.1 - 0.052 12.6 3.3 0.067 12.3 3.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Herpes_pp85 PF04637.12 EAU81648.1 - 6.3 5.1 10.5 7.8 4.8 10.5 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TFIIS_M PF07500.14 EAU81649.1 - 1.6e-33 115.5 2.4 1.7e-33 115.5 1.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EAU81649.1 - 1.9e-17 62.8 10.0 3e-17 62.2 10.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EAU81649.1 - 3.5e-11 42.9 1.5 1.1e-10 41.4 1.4 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF2062 PF09835.9 EAU81653.2 - 0.0089 15.9 1.4 0.0089 15.9 1.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2062) Glyco_hydro_88 PF07470.13 EAU81654.1 - 4e-22 78.8 0.0 5.4e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CH PF00307.31 EAU81655.2 - 0.12 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain NAM-associated PF14303.6 EAU81655.2 - 0.46 11.2 10.4 0.53 11.0 1.9 2.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Redoxin PF08534.10 EAU81656.1 - 2.3e-25 89.0 0.0 2.7e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EAU81656.1 - 9.5e-12 44.9 0.0 1.2e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family F-box-like PF12937.7 EAU81659.1 - 5.8e-06 26.1 0.4 1.3e-05 25.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU81659.1 - 0.0048 16.7 1.6 0.039 13.8 1.6 2.4 1 1 0 1 1 1 1 F-box domain MRG PF05712.13 EAU81662.2 - 3.1e-37 127.8 0.1 4.3e-28 98.0 0.0 2.1 2 0 0 2 2 2 2 MRG Tudor-knot PF11717.8 EAU81662.2 - 9.5e-10 38.2 0.1 1.8e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DSS1_SEM1 PF05160.13 EAU81663.1 - 1.2e-24 86.1 7.2 1.6e-24 85.7 7.2 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Ribosomal_S10 PF00338.22 EAU81665.2 - 7.8e-29 99.8 0.0 1.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Glyco_transf_4 PF13439.6 EAU81665.2 - 0.041 13.9 2.0 0.063 13.3 2.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 EnY2 PF10163.9 EAU81666.2 - 4.7e-16 58.9 0.2 7.6e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 Mago_nashi PF02792.14 EAU81667.1 - 2.4e-73 244.9 0.2 2.7e-73 244.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF4436 PF14494.6 EAU81668.2 - 4.4e-11 42.6 2.7 6.2e-11 42.1 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF2793 PF10983.8 EAU81670.2 - 0.073 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Hydantoinase_A PF01968.18 EAU81671.2 - 9e-95 317.3 0.2 1.5e-94 316.5 0.2 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EAU81671.2 - 2.9e-57 193.3 0.1 1.3e-54 184.6 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Sdh_cyt PF01127.22 EAU81672.2 - 0.21 11.6 2.9 0.65 10.0 0.2 2.7 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit F-box PF00646.33 EAU81673.2 - 0.0065 16.3 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EAU81673.2 - 0.013 15.2 3.4 0.11 12.3 2.2 3.0 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 EAU81673.2 - 0.056 13.3 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like Fungal_trans PF04082.18 EAU81674.2 - 2.2e-15 56.4 1.0 1.7e-14 53.5 1.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABA_WDS PF02496.16 EAU81675.2 - 0.094 13.2 0.4 0.26 11.8 0.0 1.8 2 0 0 2 2 2 0 ABA/WDS induced protein TssO PF17561.2 EAU81676.1 - 0.66 10.1 3.9 0.89 9.7 0.8 2.4 2 1 1 3 3 3 0 Type VI secretion system, TssO Tmp39 PF10271.9 EAU81676.1 - 1.5 7.7 3.9 2.8 6.8 1.3 2.0 2 0 0 2 2 2 0 Putative transmembrane protein KELK PF15796.5 EAU81676.1 - 2.6 8.6 25.2 0.6 10.6 8.2 2.8 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Glyco_hydro_61 PF03443.14 EAU81677.2 - 9.3e-44 149.8 0.0 1.1e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MHC2-interact PF09307.10 EAU81678.2 - 0.19 11.7 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting GIDA PF01134.22 EAU81679.1 - 2.8e-153 510.7 0.0 4e-153 510.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EAU81679.1 - 1.1e-56 192.3 0.0 1.6e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EAU81679.1 - 9.1e-07 28.6 0.8 1.7e-06 27.7 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU81679.1 - 1.3e-06 27.9 0.9 2e-05 24.0 0.6 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU81679.1 - 0.00023 20.4 1.7 0.00043 19.5 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAU81679.1 - 0.0012 17.6 0.6 0.053 12.2 0.3 2.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EAU81679.1 - 0.0018 17.6 0.2 0.0036 16.6 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EAU81679.1 - 0.031 13.5 0.0 0.088 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU81679.1 - 0.074 13.6 0.3 0.17 12.5 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAU81679.1 - 0.084 12.1 0.3 0.17 11.1 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 EAU81679.1 - 0.16 12.3 1.0 0.38 11.0 1.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU81679.1 - 0.17 11.4 2.5 0.86 9.1 1.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 EAU81681.2 - 1.5e-19 70.2 0.7 1.1e-14 54.4 0.4 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU81681.2 - 4.9e-09 36.1 0.1 2.5e-05 24.0 0.1 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 EAU81681.2 - 2.8e-05 24.2 0.0 6.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 EAU81681.2 - 4.5e-05 23.5 0.2 0.00013 21.9 0.2 1.8 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EAU81681.2 - 0.0013 19.0 0.2 0.0031 17.8 0.2 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EAU81681.2 - 0.01 15.0 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 EAU81681.2 - 0.079 13.4 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.25 EAU81682.2 - 3.4e-64 216.8 0.0 2.1e-59 201.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU81682.2 - 8.4e-35 120.3 0.1 5.9e-34 117.5 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EAU81682.2 - 1.1e-17 63.5 0.1 1.9e-17 62.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EAU81682.2 - 4e-06 26.3 0.1 6.9e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAU81682.2 - 6.8e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAU81682.2 - 0.00037 19.6 0.2 0.0006 18.9 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAU81682.2 - 0.00066 19.7 2.6 0.043 13.7 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.11 EAU81682.2 - 0.079 12.6 0.4 0.13 11.8 0.4 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) SPC12 PF06645.13 EAU81683.1 - 3.7e-29 100.6 1.0 4.3e-29 100.4 1.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Phage_holin_3_6 PF07332.11 EAU81683.1 - 0.012 15.6 4.6 0.016 15.2 4.6 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TMEM100 PF16311.5 EAU81683.1 - 0.063 12.9 0.3 0.07 12.7 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 Sugar_tr PF00083.24 EAU81684.2 - 1.7e-85 287.6 21.1 4.1e-84 283.0 21.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU81684.2 - 1.9e-08 33.6 38.4 5.8e-05 22.2 12.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 EAU81685.2 - 5e-07 29.5 0.2 1.3e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU81685.2 - 0.00038 20.8 5.0 2.6 8.6 0.2 5.2 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) Pkinase PF00069.25 EAU81687.2 - 4.4e-71 239.3 0.0 5.2e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU81687.2 - 1.3e-31 109.8 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAU81687.2 - 0.0002 20.4 0.6 0.0041 16.1 0.6 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAU81687.2 - 0.0026 17.7 0.2 0.0076 16.2 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAU81687.2 - 0.032 13.3 0.0 0.073 12.1 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 EAU81687.2 - 0.05 12.9 0.0 0.15 11.4 0.0 1.7 1 1 1 2 2 2 0 Kinase-like ATP_bind_1 PF03029.17 EAU81688.1 - 1.9e-75 253.8 0.0 3e-75 253.1 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EAU81688.1 - 6.1e-05 22.6 0.0 0.0017 17.9 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAU81688.1 - 0.0003 20.9 0.0 0.0016 18.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EAU81688.1 - 0.0023 17.7 0.0 0.0051 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EAU81688.1 - 0.003 16.6 0.0 0.81 8.6 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EAU81688.1 - 0.0036 16.9 0.1 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAU81688.1 - 0.0097 15.8 0.0 1.3 8.9 0.0 2.9 3 1 0 3 3 3 1 RsgA GTPase G-alpha PF00503.20 EAU81688.1 - 0.012 14.8 0.5 0.36 9.9 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.6 EAU81688.1 - 0.013 15.6 0.0 0.042 14.0 0.0 1.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAU81688.1 - 0.021 14.9 0.1 5.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 EAU81688.1 - 0.024 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GrpE PF01025.19 EAU81688.1 - 0.034 13.8 2.1 5.7 6.6 0.0 2.3 1 1 1 2 2 2 0 GrpE PAPA-1 PF04795.12 EAU81688.1 - 0.035 14.9 0.3 0.066 14.0 0.3 1.4 1 0 0 1 1 1 0 PAPA-1-like conserved region cobW PF02492.19 EAU81688.1 - 0.038 13.6 0.1 4.5 6.8 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EAU81688.1 - 0.1 12.5 0.1 1.7 8.5 0.0 2.4 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 EAU81688.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arf PF00025.21 EAU81688.1 - 0.13 11.7 0.0 0.75 9.2 0.0 2.2 3 0 0 3 3 3 0 ADP-ribosylation factor family SAD_SRA PF02182.17 EAU81689.1 - 7.9e-54 181.6 0.4 9.2e-54 181.4 0.4 1.0 1 0 0 1 1 1 1 SAD/SRA domain adh_short PF00106.25 EAU81690.1 - 8.4e-24 84.1 0.0 3.8e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU81690.1 - 4.8e-15 55.8 0.0 1.9e-12 47.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU81690.1 - 4.8e-05 23.3 0.0 8.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAU81690.1 - 0.002 17.3 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EAU81690.1 - 0.0028 17.7 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TPPII_N PF12583.8 EAU81691.1 - 1.4 9.5 7.8 87 3.7 0.1 4.5 1 1 4 5 5 5 0 Tripeptidyl peptidase II N terminal NACHT PF05729.12 EAU81692.2 - 2.1e-09 37.5 0.1 1.3e-07 31.7 0.0 3.1 4 0 0 4 4 4 1 NACHT domain AAA_16 PF13191.6 EAU81692.2 - 0.00019 21.9 0.1 0.0012 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU81692.2 - 0.0056 17.0 0.0 0.028 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU81692.2 - 0.02 14.6 0.1 0.044 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF3350 PF11830.8 EAU81692.2 - 0.14 12.5 0.3 0.36 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) TsaE PF02367.17 EAU81692.2 - 0.27 11.2 1.1 1.6 8.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE BTB PF00651.31 EAU81693.2 - 2.7e-13 50.1 0.0 7.2e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain HATPase_c_3 PF13589.6 EAU81693.2 - 0.0086 15.9 0.1 8.2 6.3 0.0 3.1 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF455 PF04305.14 EAU81694.2 - 9.1e-87 290.7 0.1 1.2e-86 290.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 EAU81694.2 - 8.9e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EAU81694.2 - 0.038 13.9 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain TMEM51 PF15345.6 EAU81695.2 - 0.011 15.6 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 SKG6 PF08693.10 EAU81695.2 - 0.025 14.0 2.4 0.025 14.0 2.4 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Stevor PF17410.2 EAU81695.2 - 0.19 11.3 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CD34_antigen PF06365.12 EAU81695.2 - 0.2 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF1708 PF08101.11 EAU81697.1 - 3.2e-19 69.4 0.0 1.1e-18 67.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 EAU81697.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain Dyp_perox PF04261.12 EAU81698.1 - 6.9e-07 28.6 0.1 3.2e-05 23.1 0.0 3.1 3 1 0 3 3 3 1 Dyp-type peroxidase family DUF2470 PF10615.9 EAU81699.1 - 8.1e-19 68.0 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 EAU81699.1 - 2.4e-10 40.6 0.9 4.6e-10 39.7 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) RSD-2 PF07547.13 EAU81699.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 RSD-2 N-terminal domain DUF2279 PF10043.9 EAU81699.1 - 0.13 13.1 0.0 0.25 12.2 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2279) NACHT PF05729.12 EAU81701.2 - 3.3e-13 49.9 0.1 6e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU81701.2 - 6.9e-07 29.8 0.0 2.5e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAU81701.2 - 0.00025 21.5 0.0 0.00071 20.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EAU81701.2 - 0.00065 18.9 0.1 0.083 12.0 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 EAU81701.2 - 0.00099 19.4 0.0 0.0047 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EAU81701.2 - 0.0017 18.1 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EAU81701.2 - 0.019 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EAU81701.2 - 0.02 15.0 0.0 0.077 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 EAU81701.2 - 0.057 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.22 EAU81701.2 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EAU81701.2 - 0.15 12.5 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 EAU81701.2 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 EAU81701.2 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 EAU81701.2 - 0.18 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF262 PF03235.14 EAU81702.2 - 2.5e-17 63.8 4.9 6.6e-17 62.4 4.9 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF262 APC_u15 PF16636.5 EAU81702.2 - 0.54 10.7 8.8 1.9 8.9 7.0 3.2 1 1 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 Pkinase PF00069.25 EAU81703.2 - 5.2e-25 88.3 0.0 8.9e-24 84.3 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU81703.2 - 5.2e-09 35.8 0.0 0.045 13.0 0.0 3.8 4 0 0 4 4 4 3 Protein tyrosine kinase adh_short PF00106.25 EAU81704.1 - 1.5e-22 80.0 0.0 6.6e-20 71.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU81704.1 - 1.6e-13 50.7 0.1 5.4e-12 45.8 0.1 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU81704.1 - 1.1e-05 25.4 0.1 2.7e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 KR domain DUF4449 PF14613.6 EAU81705.1 - 6.6e-15 55.6 0.0 6.6e-15 55.6 0.0 4.4 5 1 1 6 6 6 1 Protein of unknown function (DUF4449) TED PF08341.11 EAU81705.1 - 0.0045 17.3 0.5 0.017 15.5 0.5 2.0 1 0 0 1 1 1 1 Thioester domain RNase_H2-Ydr279 PF09468.10 EAU81705.1 - 0.011 16.0 2.8 0.037 14.2 2.8 2.2 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF4521 PF15021.6 EAU81705.1 - 0.014 15.3 2.3 0.022 14.7 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4521) Myb_DNA-bind_3 PF12776.7 EAU81705.1 - 0.12 13.4 4.2 4.2 8.4 1.4 2.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Apolipoprotein PF01442.18 EAU81705.1 - 0.12 12.2 35.7 0.079 12.8 0.5 5.0 2 1 3 5 5 5 0 Apolipoprotein A1/A4/E domain FTO_CTD PF12934.7 EAU81705.1 - 0.19 11.5 3.1 1 9.1 0.8 2.6 2 0 0 2 2 2 0 FTO C-terminal domain HisKA_3 PF07730.13 EAU81705.1 - 0.61 10.6 6.8 5.4 7.6 0.2 4.9 5 1 1 6 6 5 0 Histidine kinase Flu_NS2 PF00601.19 EAU81705.1 - 1.3 9.3 3.5 42 4.5 0.1 3.5 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) eIF3m_C_helix PF18005.1 EAU81705.1 - 2.8 7.7 7.7 7.8 6.3 2.3 2.8 2 0 0 2 2 2 0 eIF3 subunit M, C-terminal helix DUF2379 PF09543.10 EAU81705.1 - 3.8 7.7 7.6 0.46 10.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2379) TMEM154 PF15102.6 EAU81706.1 - 0.0046 16.9 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family DUF2076 PF09849.9 EAU81707.2 - 1 9.3 12.8 1.6 8.7 12.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 EAU81707.2 - 4.7 7.1 10.5 5.4 6.9 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EAU81707.2 - 5.7 5.5 11.1 6.1 5.4 11.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SH3_1 PF00018.28 EAU81708.2 - 2.9e-05 23.6 0.0 2.9e-05 23.6 0.0 3.1 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 EAU81708.2 - 0.00028 20.7 0.0 0.00063 19.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LPG_synthase_TM PF03706.13 EAU81708.2 - 0.025 14.1 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region SH3_2 PF07653.17 EAU81708.2 - 0.03 14.0 0.0 0.03 14.0 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain VirB3 PF05101.13 EAU81708.2 - 0.12 12.6 0.8 0.22 11.7 0.8 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DUF2207 PF09972.9 EAU81708.2 - 0.16 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5305 PF17231.2 EAU81708.2 - 0.26 10.7 0.0 0.42 10.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) BTB PF00651.31 EAU81709.2 - 1.4e-12 47.8 0.1 4e-12 46.3 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain HATPase_c_3 PF13589.6 EAU81709.2 - 0.14 11.9 0.1 16 5.4 0.1 3.0 2 2 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phosphodiest PF01663.22 EAU81710.2 - 4.5e-10 39.6 0.4 8.2e-10 38.8 0.1 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EAU81710.2 - 0.00019 20.9 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EAU81710.2 - 0.0027 17.2 0.3 0.014 14.8 0.3 2.0 1 1 0 1 1 1 1 Sulfatase F-box PF00646.33 EAU81711.2 - 7e-07 29.0 1.1 1.7e-06 27.8 1.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU81711.2 - 4.1e-05 23.4 0.9 0.00013 21.8 0.9 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU81711.2 - 0.067 13.1 0.8 0.13 12.1 0.8 1.5 1 0 0 1 1 1 0 F-box AA_permease_2 PF13520.6 EAU81715.2 - 6e-25 87.9 28.0 1.4e-14 53.7 14.0 2.0 2 0 0 2 2 2 2 Amino acid permease Rft-1 PF04506.13 EAU81715.2 - 0.01 14.6 1.2 0.03 13.1 1.2 1.7 1 0 0 1 1 1 0 Rft protein Phage_glycop_gL PF11108.8 EAU81715.2 - 0.12 12.4 0.4 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 Viral glycoprotein L OppC_N PF12911.7 EAU81715.2 - 2.5 8.1 11.5 0.17 11.9 1.9 3.4 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Proteasome PF00227.26 EAU81717.2 - 1.1e-30 106.6 0.2 1.2e-30 106.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1996 PF09362.10 EAU81719.2 - 4.6e-64 216.6 0.0 6.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Sugar_tr PF00083.24 EAU81720.2 - 1.1e-92 311.2 21.3 1.3e-92 311.0 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU81720.2 - 1.3e-21 76.9 38.0 1.6e-19 70.1 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Esterase_phd PF10503.9 EAU81722.1 - 7.5e-17 61.6 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EAU81722.1 - 8.7e-14 51.2 6.3 8.7e-14 51.2 6.3 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EAU81722.1 - 3.6e-08 33.2 0.2 6.3e-08 32.3 0.2 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 EAU81722.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EAU81722.1 - 0.02 14.7 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EAU81722.1 - 0.029 14.0 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 EAU81722.1 - 0.058 12.6 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 EAU81722.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1264 PF06884.11 EAU81723.1 - 1.6e-76 255.7 0.0 2.4e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TPR_11 PF13414.6 EAU81724.1 - 1.1e-09 37.8 2.2 2.9e-06 26.8 0.8 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 EAU81724.1 - 7e-09 35.1 1.9 0.0003 20.7 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAU81724.1 - 3.1e-06 27.2 0.6 6.5e-06 26.2 0.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat zf_CCCH_4 PF18345.1 EAU81724.1 - 3.2e-06 27.0 11.4 0.0018 18.2 5.8 2.8 2 1 0 2 2 2 2 Zinc finger domain TPR_1 PF00515.28 EAU81724.1 - 1.1e-05 25.1 4.3 0.046 13.5 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-CCCH_4 PF18044.1 EAU81724.1 - 1.5e-05 24.6 11.0 0.00054 19.7 0.6 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger TPR_8 PF13181.6 EAU81724.1 - 0.00092 19.2 5.4 0.0037 17.3 0.1 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat zf-CCCH_2 PF14608.6 EAU81724.1 - 0.0017 18.8 9.9 0.065 13.7 2.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EAU81724.1 - 0.0026 17.6 10.8 0.0044 16.9 2.9 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_17 PF13431.6 EAU81724.1 - 0.0037 17.6 0.7 6.2 7.4 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Torus PF16131.5 EAU81724.1 - 0.0043 17.7 7.9 0.037 14.7 1.3 2.8 1 1 1 2 2 2 1 Torus domain TPR_19 PF14559.6 EAU81724.1 - 0.016 15.7 2.0 0.091 13.3 0.7 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU81724.1 - 0.018 15.8 4.3 1.4 10.0 1.5 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAU81724.1 - 0.026 15.2 8.2 0.26 12.0 4.7 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU81724.1 - 0.2 12.0 9.1 0.48 10.7 0.3 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU81724.1 - 0.34 11.2 3.2 0.47 10.7 1.2 2.3 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCCH_3 PF15663.5 EAU81724.1 - 2.2 8.5 5.9 55 4.0 6.1 2.2 1 1 1 2 2 2 0 Zinc-finger containing family Aldo_ket_red PF00248.21 EAU81725.1 - 4.2e-42 144.3 0.0 5.2e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family SF3b1 PF08920.10 EAU81725.1 - 0.034 14.7 0.2 0.057 13.9 0.2 1.3 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 Lactamase_B PF00753.27 EAU81726.2 - 2.1e-17 63.8 1.5 3e-17 63.3 1.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAU81726.2 - 0.00032 20.3 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_61 PF03443.14 EAU81728.2 - 7.4e-37 127.3 0.2 9e-37 127.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ChiC PF06483.11 EAU81728.2 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Chitinase C Actin PF00022.19 EAU81730.1 - 8.9e-143 475.8 0.0 4.7e-142 473.4 0.0 1.8 1 1 0 1 1 1 1 Actin GerD PF17898.1 EAU81730.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Spore germination GerD central core domain DUF4249 PF14054.6 EAU81731.2 - 0.15 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4249) Actin PF00022.19 EAU81732.2 - 2e-103 346.2 0.0 2e-96 323.1 0.0 3.0 1 1 1 2 2 2 2 Actin F-box-like PF12937.7 EAU81733.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EAU81733.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 F-box domain Rick_17kDa_Anti PF05433.15 EAU81736.2 - 0.047 13.5 4.1 0.096 12.6 4.1 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Mucin15 PF15672.5 EAU81736.2 - 0.054 13.0 0.1 0.085 12.3 0.1 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 CARDB PF07705.11 EAU81736.2 - 0.085 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 CARDB HECT PF00632.25 EAU81738.2 - 1.6e-76 257.8 0.0 1.9e-71 241.1 0.0 2.6 2 1 0 2 2 2 2 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EAU81738.2 - 0.0083 15.8 0.7 0.032 14.0 0.7 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif CorA PF01544.18 EAU81740.2 - 0.065 12.5 9.0 0.059 12.7 2.2 2.5 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein zf-MYND PF01753.18 EAU81744.1 - 2.2e-11 43.7 6.8 4e-11 42.8 6.8 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 EAU81744.1 - 0.00057 21.1 0.3 0.00099 20.3 0.3 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins F-box-like PF12937.7 EAU81746.2 - 1.1e-07 31.7 0.0 8.8e-06 25.5 0.0 3.4 2 1 1 3 3 3 1 F-box-like F-box PF00646.33 EAU81746.2 - 0.079 12.9 2.7 1.7 8.6 2.0 3.1 2 1 0 2 2 2 0 F-box domain Ubiq_cyt_C_chap PF03981.12 EAU81748.1 - 4.6e-25 88.3 0.0 7.3e-13 48.8 0.0 3.2 3 0 0 3 3 3 3 Ubiquinol-cytochrome C chaperone Cyclin PF08613.11 EAU81748.1 - 0.023 15.1 0.1 0.031 14.6 0.1 1.2 1 0 0 1 1 1 0 Cyclin SR-25 PF10500.9 EAU81748.1 - 0.14 11.8 7.3 0.29 10.7 7.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MAGE_N PF12440.8 EAU81748.1 - 0.67 10.7 16.2 1.6 9.5 1.8 2.2 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal IMUP PF15761.5 EAU81748.1 - 5.8 7.6 12.0 0.52 11.0 5.5 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein SSP160 PF06933.11 EAU81748.1 - 6.9 4.7 8.3 11 4.1 8.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Aminotran_1_2 PF00155.21 EAU81749.2 - 7.2e-18 64.9 0.0 3.5e-09 36.3 0.0 3.4 4 0 0 4 4 4 2 Aminotransferase class I and II Sporozoite_P67 PF05642.11 EAU81749.2 - 0.0095 14.1 0.7 0.013 13.6 0.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SPX PF03105.19 EAU81749.2 - 0.031 14.2 4.6 0.042 13.8 4.6 1.1 1 0 0 1 1 1 0 SPX domain KDZ PF18758.1 EAU81753.2 - 3.4e-54 183.8 1.1 8.2e-54 182.6 1.1 1.7 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU81753.2 - 1.8e-29 102.0 2.1 1.2e-28 99.4 0.1 2.7 3 0 0 3 3 3 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU81753.2 - 1.8e-11 44.1 0.0 6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU81753.2 - 3.5e-06 26.9 0.0 7.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases zf-like PF04071.12 EAU81753.2 - 2.7 8.0 6.3 1.4 8.9 0.4 3.1 3 0 0 3 3 3 0 Cysteine-rich small domain SNF2_N PF00176.23 EAU81754.1 - 0.051 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain HMG14_17 PF01101.18 EAU81756.1 - 0.8 10.7 3.8 2.1 9.3 3.8 1.7 1 0 0 1 1 1 0 HMG14 and HMG17 PBP1_TM PF14812.6 EAU81757.2 - 0.39 11.1 0.0 0.39 11.1 0.0 2.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DPBB_1 PF03330.18 EAU81758.2 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase APG6_N PF17675.1 EAU81760.2 - 0.37 11.3 6.3 1 9.9 6.3 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EAU81760.2 - 0.76 10.2 2.9 6.4 7.3 0.4 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 EAU81760.2 - 1.4 9.0 4.1 3.1 7.9 4.1 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AID PF18767.1 EAU81761.2 - 0.056 13.5 0.4 0.071 13.1 0.4 1.1 1 0 0 1 1 1 0 Activation induced deaminase Metaviral_G PF09595.10 EAU81761.2 - 2.2 8.3 10.6 2.6 8.1 10.6 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein BAR PF03114.18 EAU81763.2 - 0.079 12.6 0.1 7.7 6.1 0.0 2.1 2 0 0 2 2 2 0 BAR domain Tet_JBP PF12851.7 EAU81764.2 - 4.2e-09 36.2 0.0 2.8e-08 33.5 0.0 1.9 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily KDZ PF18758.1 EAU81766.2 - 2.5e-46 158.1 0.1 5.6e-46 156.9 0.1 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU81766.2 - 2.4e-24 85.6 0.2 5.2e-24 84.5 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU81766.2 - 1.8e-07 31.2 0.0 4.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU81766.2 - 0.013 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Tropomyosin_1 PF12718.7 EAU81768.1 - 0.0001 22.5 0.3 0.0001 22.5 0.3 3.0 2 1 0 3 3 3 1 Tropomyosin like FlgN PF05130.12 EAU81768.1 - 0.0084 16.6 0.1 0.017 15.7 0.1 1.5 1 0 0 1 1 1 1 FlgN protein ABC_tran_CTD PF16326.5 EAU81768.1 - 0.016 15.5 0.8 0.016 15.5 0.8 3.5 3 1 1 4 4 4 0 ABC transporter C-terminal domain DUF1664 PF07889.12 EAU81768.1 - 0.18 11.8 0.4 0.71 9.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EAU81768.1 - 0.64 10.3 1.7 46 4.3 0.0 3.4 2 1 2 4 4 4 0 Haemolysin XhlA Nop14 PF04147.12 EAU81768.1 - 1.7 6.7 18.4 0.74 8.0 13.4 2.2 2 0 0 2 2 2 0 Nop14-like family DUF3348 PF11828.8 EAU81768.1 - 3.9 7.1 8.0 0.08 12.6 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) Astro_capsid_p PF12226.8 EAU81768.1 - 8.6 5.4 8.6 13 4.8 8.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GTF2I PF02946.14 EAU81769.1 - 0.0018 18.3 0.0 0.06 13.4 0.0 2.4 1 1 0 1 1 1 1 GTF2I-like repeat RRN3 PF05327.11 EAU81769.1 - 0.016 13.8 5.8 0.022 13.3 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EAU81769.1 - 0.017 13.5 10.6 0.023 13.0 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein HMG_box PF00505.19 EAU81769.1 - 0.019 15.3 1.3 2.2 8.7 0.0 3.5 4 0 0 4 4 4 0 HMG (high mobility group) box YL1 PF05764.13 EAU81769.1 - 0.049 13.7 14.5 0.13 12.4 14.5 1.6 1 0 0 1 1 1 0 YL1 nuclear protein HMG_box_2 PF09011.10 EAU81769.1 - 0.051 14.2 0.6 0.13 12.9 0.6 1.7 1 0 0 1 1 1 0 HMG-box domain Nop14 PF04147.12 EAU81769.1 - 0.68 8.1 12.3 0.92 7.6 12.3 1.1 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.6 EAU81769.1 - 3 8.3 15.2 7.8 6.9 15.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tet_JBP PF12851.7 EAU81773.2 - 0.00028 20.3 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily p450 PF00067.22 EAU81779.2 - 1.4e-07 30.6 0.0 1.7e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU81781.2 - 3.4e-62 210.7 0.0 5.6e-62 210.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU81782.2 - 1.5e-61 208.6 0.0 2.1e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PTR2 PF00854.21 EAU81782.2 - 0.073 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 POT family p450 PF00067.22 EAU81783.2 - 7.3e-65 219.5 0.0 9.9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU81789.2 - 5.2e-62 210.1 0.0 6.4e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_3 PF01764.25 EAU81790.2 - 2e-06 27.7 0.2 6.4e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 Lipase (class 3) TMEM65 PF10507.9 EAU81790.2 - 0.14 12.1 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 65 Vfa1 PF08432.10 EAU81791.1 - 0.61 10.4 13.1 0.92 9.8 13.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MecA PF05389.12 EAU81791.1 - 1.3 8.6 12.3 3.1 7.4 12.3 1.9 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) SAPS PF04499.15 EAU81791.1 - 2.2 6.9 7.2 2.5 6.8 7.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ribosomal_60s PF00428.19 EAU81792.1 - 0.025 15.1 15.3 0.072 13.7 0.3 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Coilin_N PF15862.5 EAU81795.1 - 0.0042 16.9 1.6 0.0042 16.9 1.6 3.5 1 1 2 3 3 3 1 Coilin N-terminus Macoilin PF09726.9 EAU81795.1 - 8.8 4.7 53.4 12 4.3 53.4 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_S7 PF00177.21 EAU81796.1 - 3.8e-30 104.5 0.3 4.9e-30 104.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MTA_R1 PF17226.2 EAU81796.1 - 0.22 11.7 1.9 0.63 10.2 0.2 2.3 2 0 0 2 2 2 0 MTA R1 domain SUV3_C PF12513.8 EAU81797.1 - 3.3e-14 52.5 0.6 7.7e-14 51.4 0.6 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EAU81797.1 - 2.3e-11 44.0 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LrgB PF04172.16 EAU81798.1 - 7.5e-05 22.3 0.9 9.4e-05 22.0 0.9 1.1 1 0 0 1 1 1 1 LrgB-like family Mito_carr PF00153.27 EAU81800.1 - 3.8e-30 103.7 3.4 3.8e-15 55.6 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FAM199X PF15814.5 EAU81802.2 - 2.2 7.3 5.3 3.2 6.7 5.3 1.1 1 0 0 1 1 1 0 Protein family FAM199X RAP1 PF07218.11 EAU81802.2 - 3.7 5.7 10.3 4.5 5.4 10.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SOG2 PF10428.9 EAU81802.2 - 7.5 5.6 9.4 9.4 5.3 9.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein F-box-like PF12937.7 EAU81803.1 - 3.4e-05 23.6 2.3 5.2e-05 23.1 0.4 2.4 2 1 0 2 2 2 1 F-box-like LRR_2 PF07723.13 EAU81803.1 - 0.3 11.8 1.7 18 6.2 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat p450 PF00067.22 EAU81805.2 - 1.6e-72 244.8 0.0 1.9e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 gpUL132 PF11359.8 EAU81805.2 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 p450 PF00067.22 EAU81806.2 - 6.9e-73 246.0 0.0 8.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF2A PF08662.11 EAU81809.2 - 2.2e-80 269.1 0.0 5.7e-80 267.8 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EAU81809.2 - 0.019 15.8 0.2 1.3 10.0 0.1 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Proteasome_A_N PF10584.9 EAU81809.2 - 0.15 11.7 4.0 13 5.6 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 EAU81809.2 - 1.1 9.2 3.1 58 3.8 0.2 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CxC4 PF18717.1 EAU81812.2 - 3.9e-46 156.1 0.2 8.3e-46 155.1 0.2 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases Ribosomal_S30AE PF02482.19 EAU81813.1 - 0.011 16.5 0.6 0.019 15.8 0.6 1.3 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein SWI-SNF_Ssr4 PF08549.10 EAU81813.1 - 0.02 13.6 6.8 0.0094 14.6 1.3 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Laminin_II PF06009.12 EAU81813.1 - 0.026 14.6 3.2 0.081 12.9 2.5 1.9 2 0 0 2 2 2 0 Laminin Domain II Csm2_III-A PF03750.13 EAU81813.1 - 0.033 15.0 1.0 0.059 14.2 1.0 1.3 1 0 0 1 1 1 0 Csm2 Type III-A DUF241 PF03087.14 EAU81813.1 - 0.096 12.5 2.8 0.37 10.6 2.7 1.7 1 1 1 2 2 2 0 Arabidopsis protein of unknown function Matrilin_ccoil PF10393.9 EAU81813.1 - 3.9 7.4 5.4 4.9 7.1 1.3 2.6 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin MethyltransfD12 PF02086.15 EAU81814.1 - 0.018 14.7 1.6 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase SWIRM-assoc_3 PF16498.5 EAU81814.1 - 0.071 13.4 0.0 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal DUF3873 PF12989.7 EAU81814.1 - 0.084 13.3 0.9 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) DUF4407 PF14362.6 EAU81816.2 - 0.21 10.9 0.2 0.23 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1932 PF09130.11 EAU81819.1 - 0.012 15.6 0.2 0.59 10.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1932) FlgN PF05130.12 EAU81820.1 - 0.16 12.5 1.6 1.7 9.2 1.7 2.0 1 1 1 2 2 2 0 FlgN protein zf-HIT PF04438.16 EAU81821.2 - 2.5 8.0 7.8 0.92 9.4 1.5 2.3 2 0 0 2 2 2 0 HIT zinc finger CENP-K PF11802.8 EAU81824.2 - 0.016 14.8 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Sec2p PF06428.11 EAU81824.2 - 0.034 14.1 0.4 0.066 13.2 0.4 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Tropomyosin_1 PF12718.7 EAU81824.2 - 0.052 13.7 0.2 0.095 12.9 0.2 1.4 1 0 0 1 1 1 0 Tropomyosin like Sigma70_ner PF04546.13 EAU81826.2 - 0.39 10.6 7.4 0.87 9.4 7.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region eIF3_subunit PF08597.10 EAU81826.2 - 3.4 7.5 14.6 0.5 10.2 10.1 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit BSP_II PF05432.11 EAU81826.2 - 4.1 7.0 19.5 0.038 13.7 11.2 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) KDZ PF18758.1 EAU81827.2 - 7.2e-49 166.4 0.3 1.2e-48 165.7 0.3 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU81827.2 - 1.4e-22 79.8 0.1 4e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU81827.2 - 0.0017 18.5 0.0 0.0047 17.1 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases DUF2096 PF09869.9 EAU81827.2 - 0.042 13.9 1.1 0.08 13.0 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) p450 PF00067.22 EAU81832.2 - 1.6e-37 129.3 0.0 1.9e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.7 EAU81835.2 - 3.4e-11 43.4 0.0 6.8e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU81835.2 - 3e-10 40.4 0.0 5.3e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU81835.2 - 3.4e-06 27.0 0.0 0.0021 18.0 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAU81835.2 - 0.0023 18.0 0.0 0.007 16.5 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Kri1 PF05178.12 EAU81837.1 - 0.0018 18.8 2.7 0.0081 16.7 2.7 2.0 1 1 0 1 1 1 1 KRI1-like family Transglut_i_TM PF14400.6 EAU81837.1 - 0.11 12.5 0.1 0.95 9.5 0.1 2.0 1 1 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices Myb_DNA-bind_2 PF08914.11 EAU81838.2 - 3.7e-12 46.2 3.9 1.1e-11 44.7 3.9 1.9 1 1 0 1 1 1 1 Rap1 Myb domain Complex1_LYR PF05347.15 EAU81838.2 - 5.1 7.2 7.1 34 4.6 2.1 2.8 2 0 0 2 2 2 0 Complex 1 protein (LYR family) COesterase PF00135.28 EAU81840.2 - 3.9e-72 243.8 0.5 9.2e-69 232.6 0.0 2.7 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU81840.2 - 0.00021 21.2 0.3 0.026 14.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU81840.2 - 0.01 15.3 0.8 0.018 14.5 0.8 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 EAU81841.2 - 4.2e-83 280.0 0.0 6.9e-83 279.2 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU81841.2 - 3.6e-07 30.3 0.1 4.8e-06 26.6 0.1 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU81841.2 - 0.091 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family FMO-like PF00743.19 EAU81842.2 - 1.4e-15 56.7 0.0 4.1e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAU81842.2 - 8.5e-13 48.2 0.1 7.9e-12 45.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU81842.2 - 3.4e-11 42.9 0.0 3.6e-09 36.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAU81842.2 - 1.6e-09 37.4 0.0 5.1e-08 32.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EAU81842.2 - 2e-09 37.6 0.0 6.7e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU81842.2 - 0.0021 17.7 0.2 0.033 13.8 0.1 2.4 2 2 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAU81842.2 - 0.0029 17.6 0.0 0.01 15.8 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EAU81842.2 - 0.027 13.5 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EAU81842.2 - 0.053 12.8 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 EAU81842.2 - 0.3 11.7 1.0 2.8 8.5 0.3 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 EAU81843.2 - 1.1e-60 205.8 0.0 1.9e-60 204.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU81844.2 - 2.6e-65 221.0 0.0 3.4e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Per1 PF04080.13 EAU81846.1 - 2.8e-103 345.1 4.1 3.5e-103 344.8 4.1 1.1 1 0 0 1 1 1 1 Per1-like family Ribonuc_L-PSP PF01042.21 EAU81847.1 - 1.8e-22 79.6 0.0 2.2e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PC-Esterase PF13839.6 EAU81848.2 - 3.4e-07 30.3 2.3 0.0016 18.2 2.1 3.2 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MgtE PF01769.16 EAU81850.1 - 5.1e-41 139.9 17.2 2.6e-23 82.7 7.2 3.1 2 1 1 3 3 3 2 Divalent cation transporter DUF1129 PF06570.11 EAU81850.1 - 0.88 9.0 6.8 0.079 12.4 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ada3 PF10198.9 EAU81851.2 - 2e-29 102.4 3.0 2e-29 102.4 3.0 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 FH2 PF02181.23 EAU81851.2 - 0.065 12.3 0.3 0.11 11.6 0.3 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain FokI_N PF02981.15 EAU81851.2 - 0.33 11.1 1.8 5.4 7.2 0.1 2.7 4 0 0 4 4 4 0 Restriction endonuclease FokI, recognition domain RNA_polI_A34 PF08208.11 EAU81852.1 - 5e-33 114.9 19.7 5e-33 114.9 19.7 1.5 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Mak10 PF04112.13 EAU81853.1 - 7.7e-37 126.4 0.7 1.3e-36 125.7 0.0 1.6 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase XET_C PF06955.12 EAU81853.1 - 0.028 14.3 0.1 0.092 12.6 0.1 1.9 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus Polysacc_lyase PF14099.6 EAU81856.1 - 0.00014 21.8 0.3 0.0003 20.7 0.3 1.5 1 1 0 1 1 1 1 Polysaccharide lyase Polysacc_lyase PF14099.6 EAU81857.1 - 0.0095 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase Methyltransf_23 PF13489.6 EAU81858.2 - 4.2e-16 59.2 0.0 5.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU81858.2 - 5.3e-15 55.9 0.0 1.1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU81858.2 - 2.9e-13 50.3 0.0 5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU81858.2 - 7.8e-11 42.0 0.0 2e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU81858.2 - 1e-10 42.2 0.0 2.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU81858.2 - 8.3e-06 25.3 0.0 1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EAU81858.2 - 3.7e-05 23.9 0.2 6.2e-05 23.2 0.2 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EAU81858.2 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EAU81858.2 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EAU81858.2 - 0.0056 16.1 0.0 0.0081 15.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EAU81858.2 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EAU81858.2 - 0.037 13.1 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DREV PF05219.12 EAU81858.2 - 0.041 13.0 0.0 0.11 11.6 0.0 1.7 1 1 0 1 1 1 0 DREV methyltransferase DUF43 PF01861.16 EAU81858.2 - 0.048 12.9 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain IMS PF00817.20 EAU81859.1 - 1.3e-41 142.1 0.5 3.3e-41 140.7 0.2 1.9 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 EAU81859.1 - 1.6e-25 89.3 3.5 3.4e-25 88.3 1.8 2.3 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 EAU81859.1 - 3.7e-16 59.9 0.0 2.6e-15 57.2 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EAU81859.1 - 3.1e-10 40.3 0.0 8.3e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 EAU81859.1 - 2.2e-05 24.5 0.3 9.5e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 IMS family HHH motif UBM PF14377.6 EAU81859.1 - 3.6e-05 23.1 2.6 0.24 10.9 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin binding region BRCT PF00533.26 EAU81859.1 - 0.00023 21.5 0.1 0.00098 19.5 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EAU81859.1 - 0.00034 20.5 0.0 0.00093 19.1 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain DUF1805 PF08827.11 EAU81859.1 - 0.023 15.0 0.0 0.082 13.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) XTBD PF11952.8 EAU81860.2 - 0.031 14.0 1.7 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD Glyco_hydro_79C PF16862.5 EAU81861.2 - 1.7e-20 73.8 0.0 4.5e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain p450 PF00067.22 EAU81862.2 - 2.6e-58 197.9 0.0 3.6e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.21 EAU81863.2 - 8.1e-28 96.8 0.0 1.3e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pribosyltran_N PF13793.6 EAU81864.1 - 1.5e-51 173.3 0.3 1.1e-50 170.4 0.1 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EAU81864.1 - 2.1e-35 122.4 1.4 3.5e-32 111.9 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EAU81864.1 - 3.7e-16 59.0 0.9 6.3e-15 55.0 0.2 2.3 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAU81864.1 - 9.9e-06 25.1 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EAU81864.1 - 0.0006 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase AA_kinase PF00696.28 EAU81865.1 - 2.7e-42 145.0 1.5 3.4e-42 144.7 0.8 1.4 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 EAU81865.1 - 1.4e-09 37.8 0.8 4e-05 23.5 0.3 2.7 2 0 0 2 2 2 2 PUA domain Hydrophobin PF01185.18 EAU81871.2 - 1.6e-23 83.1 11.0 1.9e-23 82.9 11.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CLIP_SPH_mas PF18398.1 EAU81871.2 - 0.069 13.6 6.7 0.3 11.5 1.1 2.6 3 0 0 3 3 3 0 Clip-domain serine protease homolog masquerade FAD_binding_2 PF00890.24 EAU81873.1 - 2.2e-124 415.7 3.9 2.7e-124 415.4 3.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EAU81873.1 - 3.7e-44 149.8 0.2 5.6e-44 149.2 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EAU81873.1 - 7.9e-07 28.6 0.4 0.00025 20.4 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU81873.1 - 3.2e-06 26.6 0.3 0.0051 16.1 0.0 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EAU81873.1 - 1.1e-05 24.8 1.7 0.0072 15.4 2.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EAU81873.1 - 0.0021 17.4 0.2 0.0042 16.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAU81873.1 - 0.039 13.5 1.3 0.11 12.1 1.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAU81873.1 - 0.075 12.1 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EAU81873.1 - 0.094 11.4 2.1 0.31 9.7 0.7 2.5 4 0 0 4 4 4 0 HI0933-like protein Hamartin PF04388.12 EAU81874.1 - 2.5 6.7 5.6 2.6 6.6 5.6 1.2 1 0 0 1 1 1 0 Hamartin protein Hydrophobin PF01185.18 EAU81875.2 - 3.4e-27 94.9 5.9 4.1e-27 94.6 5.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Mito_carr PF00153.27 EAU81876.2 - 6.6e-58 192.6 3.5 6.7e-20 70.8 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein V_ATPase_I PF01496.19 EAU81878.1 - 0 1044.2 0.0 0 1044.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.12 EAU81878.1 - 0.025 15.2 1.0 0.025 15.2 1.0 2.3 3 0 0 3 3 3 0 SlyX TBCC_N PF16752.5 EAU81878.1 - 0.067 13.6 1.7 3 8.3 0.8 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Mt_ATP-synt_B PF05405.14 EAU81878.1 - 0.15 11.6 0.3 0.31 10.6 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TMEM213 PF15192.6 EAU81878.1 - 0.33 10.9 1.1 0.71 9.9 1.1 1.5 1 0 0 1 1 1 0 TMEM213 family ABC_tran_CTD PF16326.5 EAU81878.1 - 0.75 10.1 4.5 2.1 8.6 3.0 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain ABC_tran PF00005.27 EAU81879.1 - 1.3e-44 152.0 0.1 6.3e-22 78.6 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EAU81879.1 - 4e-18 66.3 2.6 2.3e-07 31.0 0.6 4.6 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU81879.1 - 8.3e-14 51.6 0.8 0.00095 18.7 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAU81879.1 - 2.6e-09 37.9 0.4 0.003 18.1 0.6 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAU81879.1 - 1.9e-08 33.9 0.2 0.0033 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAU81879.1 - 2.4e-06 27.9 0.0 0.074 13.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 EAU81879.1 - 4.7e-06 26.9 0.1 0.0045 17.1 0.1 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_18 PF13238.6 EAU81879.1 - 6.8e-06 26.7 0.1 0.032 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EAU81879.1 - 7.4e-06 26.0 0.0 0.26 11.4 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EAU81879.1 - 1.4e-05 25.4 0.0 0.1 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EAU81879.1 - 1.6e-05 24.9 0.1 0.045 13.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EAU81879.1 - 2.8e-05 24.6 1.6 0.026 14.9 0.0 3.8 4 1 0 4 4 3 1 AAA ATPase domain AAA_15 PF13175.6 EAU81879.1 - 6.1e-05 22.9 0.7 0.47 10.1 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 EAU81879.1 - 8.2e-05 23.0 0.0 1.9 8.9 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAU81879.1 - 0.00022 21.6 0.0 0.78 10.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase MeaB PF03308.16 EAU81879.1 - 0.00024 20.2 2.8 0.29 10.1 0.1 3.3 3 1 1 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EAU81879.1 - 0.00041 20.5 0.0 1.7 8.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAU81879.1 - 0.0013 18.5 0.3 4.5 7.0 0.0 3.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EAU81879.1 - 0.0015 18.5 1.0 1 9.2 0.1 2.9 2 1 0 2 2 2 1 NACHT domain HEAT_2 PF13646.6 EAU81879.1 - 0.0015 18.9 17.6 0.058 13.8 0.4 5.0 5 1 0 5 5 4 1 HEAT repeats AAA_24 PF13479.6 EAU81879.1 - 0.0019 17.9 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAU81879.1 - 0.0035 16.9 0.3 3.1 7.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_13 PF13166.6 EAU81879.1 - 0.004 15.9 0.0 2.3 6.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EAU81879.1 - 0.0046 17.2 0.1 1.3 9.3 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 EAU81879.1 - 0.0053 16.0 0.2 2.6 7.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) 4HB PF17947.1 EAU81879.1 - 0.0054 16.8 0.1 0.025 14.7 0.1 2.1 1 0 0 1 1 1 1 Four helical bundle domain Chromo PF00385.24 EAU81879.1 - 0.007 16.3 0.2 0.018 14.9 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ATPase_2 PF01637.18 EAU81879.1 - 0.0087 16.0 3.9 5.7 6.8 0.0 3.9 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 EAU81879.1 - 0.026 14.8 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EAU81879.1 - 0.027 14.5 0.3 10 6.1 0.1 2.6 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 EAU81879.1 - 0.029 13.5 0.2 1.4 8.0 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 EAU81879.1 - 0.036 13.2 0.0 5 6.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain CLP1_P PF16575.5 EAU81879.1 - 0.057 13.2 1.7 12 5.6 0.0 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NTPase_1 PF03266.15 EAU81879.1 - 0.062 13.2 0.1 8 6.3 0.0 2.8 2 0 0 2 2 2 0 NTPase DUF3437 PF11919.8 EAU81879.1 - 0.063 13.2 1.3 0.67 9.9 0.1 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF3437) Dynamin_N PF00350.23 EAU81879.1 - 0.071 13.2 0.2 0.94 9.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_27 PF13514.6 EAU81879.1 - 0.076 12.6 0.6 11 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.14 EAU81879.1 - 0.11 11.7 1.3 0.26 10.5 0.0 2.2 3 0 0 3 3 3 0 KAP family P-loop domain ATP-synt_ab PF00006.25 EAU81879.1 - 0.17 11.5 1.5 3.7 7.2 0.0 3.4 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 EAU81879.1 - 0.21 11.6 0.6 18 5.3 0.7 3.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAU81879.1 - 0.48 10.4 6.7 7.3 6.6 0.1 4.5 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) U3snoRNP10 PF12397.8 EAU81879.1 - 0.49 10.8 2.6 1.1 9.6 1.0 2.5 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Zeta_toxin PF06414.12 EAU81879.1 - 0.9 8.8 4.6 12 5.1 0.1 3.8 4 0 0 4 4 4 0 Zeta toxin HEAT PF02985.22 EAU81879.1 - 1.2 9.6 4.6 88 3.8 0.0 4.8 5 0 0 5 5 3 0 HEAT repeat F-box-like PF12937.7 EAU81881.1 - 6.9e-06 25.9 0.9 2.6e-05 24.0 0.9 2.1 1 0 0 1 1 1 1 F-box-like Oxidored_q3 PF00499.20 EAU81882.1 - 0.024 14.4 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 AA_permease_2 PF13520.6 EAU81882.1 - 0.034 13.0 1.6 0.071 11.9 1.8 1.4 1 1 0 1 1 1 0 Amino acid permease 7TMR-DISM_7TM PF07695.11 EAU81884.2 - 0.0055 16.6 0.5 0.0071 16.3 0.5 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling Ras PF00071.22 EAU81885.1 - 1.4e-62 210.0 0.2 1.7e-62 209.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU81885.1 - 9.4e-35 119.4 0.1 1.4e-34 118.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU81885.1 - 6.5e-12 45.2 0.0 8.4e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAU81885.1 - 4.1e-07 30.1 0.1 6.3e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU81885.1 - 8.6e-05 22.5 0.1 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAU81885.1 - 0.00021 20.9 0.2 0.00074 19.1 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EAU81885.1 - 0.0032 17.7 0.0 0.037 14.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EAU81885.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EAU81885.1 - 0.016 15.0 0.0 0.051 13.3 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EAU81885.1 - 0.016 15.6 0.1 0.027 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 EAU81885.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EAU81885.1 - 0.032 13.8 0.2 0.095 12.2 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 EAU81885.1 - 0.032 14.8 0.1 0.053 14.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EAU81885.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 1 0 2 2 2 0 AAA domain TniB PF05621.11 EAU81885.1 - 0.09 12.2 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein MCM PF00493.23 EAU81885.1 - 0.096 11.8 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 EAU81885.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region YvfG PF09628.10 EAU81885.1 - 0.15 12.4 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 YvfG protein AAA_5 PF07728.14 EAU81885.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EAU81885.1 - 0.18 11.6 0.7 0.28 10.9 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system F-box-like PF12937.7 EAU81886.1 - 0.00064 19.6 0.0 0.0019 18.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU81886.1 - 0.0017 18.2 0.1 0.006 16.4 0.0 1.9 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 EAU81886.1 - 0.14 12.6 1.3 0.63 10.6 0.2 2.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Peptidase_M50B PF13398.6 EAU81887.2 - 2e-50 171.2 18.2 3e-50 170.7 18.2 1.2 1 0 0 1 1 1 1 Peptidase M50B-like CDP-OH_P_transf PF01066.21 EAU81887.2 - 0.27 12.0 6.8 1.6 9.5 6.8 2.5 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase p450 PF00067.22 EAU81889.2 - 1.6e-62 211.7 0.0 2.9e-62 210.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Plavaka PF18759.1 EAU81890.2 - 9.1e-32 110.6 0.0 1.9e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 Plavaka transposase Strep_his_triad PF04270.13 EAU81890.2 - 0.19 11.8 1.1 12 6.0 0.2 2.8 2 0 0 2 2 2 0 Streptococcal histidine triad protein LepB_GAP_N PF18172.1 EAU81892.2 - 0.043 13.7 0.4 0.081 12.8 0.4 1.4 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain RMI1_N PF08585.12 EAU81894.2 - 2.3e-11 43.9 0.0 3.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Hydrophobin PF01185.18 EAU81903.1 - 7.7e-22 77.7 8.2 9.4e-22 77.5 8.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AMP-binding PF00501.28 EAU81904.1 - 8.6e-87 291.4 0.0 1.1e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU81904.1 - 0.036 15.0 0.0 0.083 13.9 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain KDZ PF18758.1 EAU81905.2 - 9.9e-48 162.7 0.0 1.8e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 EAU81905.2 - 2.9e-12 46.9 0.0 5.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 EAU81905.2 - 2.3e-09 37.3 0.1 5.7e-09 36.1 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU81905.2 - 0.028 14.6 0.2 0.061 13.5 0.2 1.5 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Pox_Ag35 PF03286.14 EAU81906.2 - 0.061 13.1 8.9 2.5 7.9 8.0 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-I PF07778.11 EAU81906.2 - 0.1 11.3 3.1 0.12 11.0 3.1 1.1 1 0 0 1 1 1 0 Mis6 Mu-like_Pro PF10123.9 EAU81906.2 - 0.19 11.2 6.3 0.24 10.9 6.3 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein OmpH PF03938.14 EAU81906.2 - 0.64 10.4 12.5 1.3 9.4 12.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Paramyxo_ncap PF00973.19 EAU81906.2 - 1.2 8.0 7.6 1.6 7.6 7.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Spem1 PF15670.5 EAU81906.2 - 1.5 8.4 10.1 2.1 7.8 10.1 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 Neur_chan_memb PF02932.16 EAU81906.2 - 6.1 6.8 7.4 8.8 6.3 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EAU81906.2 - 7.4 5.2 7.0 8 5.1 7.0 1.1 1 0 0 1 1 1 0 Presenilin Cauli_VI PF01693.16 EAU81908.1 - 0.015 15.6 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 Caulimovirus viroplasmin Nop14 PF04147.12 EAU81909.2 - 0.067 11.4 13.0 0.079 11.2 13.0 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EAU81909.2 - 0.17 11.3 16.4 0.21 11.0 16.4 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EAU81909.2 - 0.2 11.4 20.2 0.31 10.7 20.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EAU81909.2 - 0.78 9.0 17.4 1.2 8.4 17.4 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 EAU81909.2 - 1.9 8.7 20.2 3.2 8.0 20.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 EAU81909.2 - 8.6 4.5 13.9 12 4.1 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 EAU81911.1 - 0.0022 16.8 0.0 0.022 13.5 0.1 2.3 2 1 0 2 2 2 1 Cytochrome P450 RhoGEF PF00621.20 EAU81913.2 - 6.1e-38 130.9 6.5 1.2e-37 129.9 6.5 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 EAU81913.2 - 1.1e-21 76.4 4.7 3.3e-11 42.9 0.4 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 EAU81913.2 - 1.8e-18 65.9 5.0 3.1e-11 42.7 0.1 2.8 3 0 0 3 3 3 2 SH3 domain EF-hand_4 PF12763.7 EAU81913.2 - 9.2e-15 54.5 0.0 2.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.17 EAU81913.2 - 3e-13 49.2 0.0 1.5e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 EAU81913.2 - 1.3e-10 41.3 0.0 1.3e-10 41.3 0.0 3.4 3 1 0 3 3 2 1 Pleckstrin homology domain WH2 PF02205.20 EAU81913.2 - 6.6e-05 22.6 0.0 0.00021 21.0 0.0 1.9 1 0 0 1 1 1 1 WH2 motif PH PF00169.29 EAU81913.2 - 7.9e-05 23.1 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 EAU81913.2 - 0.00019 20.7 0.1 0.28 10.9 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EAU81913.2 - 0.00054 20.4 0.0 0.0065 16.9 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain pair SH3_10 PF17902.1 EAU81913.2 - 0.024 14.7 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 SH3 domain EF-hand_6 PF13405.6 EAU81913.2 - 0.12 12.4 0.1 8.2 6.6 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Vma12 PF11712.8 EAU81913.2 - 2.7 8.1 4.9 18 5.4 4.6 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase F-box-like PF12937.7 EAU81915.2 - 3.8e-07 29.9 3.5 1.2e-06 28.3 3.5 1.9 1 0 0 1 1 1 1 F-box-like TPR_10 PF13374.6 EAU81916.2 - 2.5e-31 106.6 6.7 0.00057 19.7 0.0 8.8 8 0 0 8 8 8 7 Tetratricopeptide repeat CHAT PF12770.7 EAU81916.2 - 4.5e-30 105.1 0.0 8.1e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU81916.2 - 2.9e-07 30.7 0.5 3.9 7.8 0.0 7.0 6 2 3 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU81916.2 - 5.2e-05 23.8 3.5 4.6 8.0 0.1 5.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU81916.2 - 0.0089 15.7 0.0 17 5.2 0.0 4.7 6 0 0 6 6 6 1 TPR repeat TniB PF05621.11 EAU81916.2 - 0.066 12.6 0.0 1.1 8.6 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein TPR_8 PF13181.6 EAU81916.2 - 0.1 12.9 0.0 55 4.3 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat F-box PF00646.33 EAU81917.2 - 1.7e-06 27.7 0.1 2.7e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU81917.2 - 0.0019 18.0 0.4 0.0032 17.3 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU81918.2 - 0.0075 16.1 0.7 0.021 14.7 0.7 1.8 1 0 0 1 1 1 1 F-box-like CBM_21 PF03370.13 EAU81920.2 - 1.7e-28 99.0 0.0 2.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EAU81920.2 - 4.9e-10 39.8 0.1 9.6e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) ADK PF00406.22 EAU81921.1 - 1.4e-58 197.3 0.0 1.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAU81921.1 - 1.6e-21 77.2 0.1 4.2e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EAU81921.1 - 5.7e-17 61.4 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EAU81921.1 - 0.00099 19.7 0.0 0.0019 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAU81921.1 - 0.0033 17.6 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain p450 PF00067.22 EAU81922.1 - 1.3e-69 235.1 0.0 1.8e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU81926.2 - 1.2e-39 136.3 0.1 2.4e-16 59.5 0.0 3.7 3 1 1 4 4 4 3 Cytochrome P450 p450 PF00067.22 EAU81927.1 - 6.2e-68 229.6 0.0 8.2e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4083 PF13314.6 EAU81927.1 - 0.16 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) p450 PF00067.22 EAU81929.2 - 7.5e-69 232.7 0.0 1.5e-68 231.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Fusion_gly_K PF01621.17 EAU81931.2 - 0.17 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Cell fusion glycoprotein K Antimicrobial_2 PF08023.12 EAU81932.1 - 0.025 15.1 4.3 0.12 12.9 1.0 2.3 2 0 0 2 2 2 0 Frog antimicrobial peptide THUMP PF02926.17 EAU81933.1 - 3.3e-14 53.2 0.8 4.6e-14 52.7 0.8 1.2 1 0 0 1 1 1 1 THUMP domain KSHV_K8 PF07188.11 EAU81933.1 - 0.052 12.9 0.1 0.075 12.4 0.1 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein F-box-like PF12937.7 EAU81934.1 - 0.0023 17.8 0.2 0.0062 16.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like IPK PF03770.16 EAU81936.1 - 1.6e-44 152.2 0.0 2.2e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_60s PF00428.19 EAU81936.1 - 0.0044 17.6 9.7 0.011 16.3 9.7 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein GCIP PF13324.6 EAU81936.1 - 0.089 12.4 1.8 0.14 11.7 1.8 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EAU81936.1 - 0.093 13.1 8.7 0.18 12.2 8.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EAU81936.1 - 0.31 10.3 8.5 0.46 9.8 8.5 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 EAU81936.1 - 1.4 8.5 4.3 2.9 7.6 4.3 1.4 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 EAU81936.1 - 4.8 7.5 10.5 18 5.6 8.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Methyltransf_31 PF13847.6 EAU81938.1 - 1.6e-19 70.2 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU81938.1 - 6.5e-17 62.0 0.0 1.2e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU81938.1 - 8.8e-17 61.6 0.0 1.8e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.10 EAU81938.1 - 3.8e-15 55.9 0.1 7.1e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.20 EAU81938.1 - 7.5e-14 51.7 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EAU81938.1 - 3.7e-12 46.4 0.0 5.6e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU81938.1 - 7.3e-11 42.7 0.0 1.7e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU81938.1 - 4.6e-08 32.7 0.0 8.5e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EAU81938.1 - 4e-06 26.7 0.0 6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EAU81938.1 - 0.00027 20.5 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EAU81938.1 - 0.00052 19.6 0.0 0.00076 19.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 EAU81938.1 - 0.00065 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_2 PF00891.18 EAU81938.1 - 0.0012 18.2 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 EAU81938.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 EAU81938.1 - 0.0024 18.8 0.0 0.0093 17.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 EAU81938.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.17 EAU81938.1 - 0.075 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 EAU81938.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Helicase_C PF00271.31 EAU81942.1 - 2.8e-08 34.1 0.0 4.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain adh_short PF00106.25 EAU81947.1 - 9.4e-47 159.0 0.2 1.6e-46 158.2 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU81947.1 - 2.1e-46 158.4 0.0 3e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU81947.1 - 2e-07 31.1 0.0 2.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAU81947.1 - 0.002 17.3 0.1 0.0029 16.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Big_9 PF17963.1 EAU81947.1 - 0.012 16.4 0.1 0.022 15.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig domain 3HCDH_N PF02737.18 EAU81947.1 - 0.013 15.4 0.2 0.019 14.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EAU81947.1 - 0.026 14.9 0.2 0.049 14.1 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 EAU81947.1 - 0.042 13.2 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cadherin_5 PF17892.1 EAU81947.1 - 0.096 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like domain F-box-like PF12937.7 EAU81948.2 - 0.0079 16.1 0.3 0.014 15.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like Glyco_hydro_20 PF00728.22 EAU81953.2 - 0.29 10.5 1.6 6.2 6.1 0.8 3.1 3 1 0 3 3 3 0 Glycosyl hydrolase family 20, catalytic domain Ribosomal_S14 PF00253.21 EAU81953.2 - 7.1 6.5 5.7 0.95 9.3 1.3 1.7 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e F-box PF00646.33 EAU81954.1 - 0.00064 19.5 0.1 0.00088 19.1 0.1 1.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU81954.1 - 0.092 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 F-box-like CDC45 PF02724.14 EAU81954.1 - 0.31 9.3 6.7 0.36 9.1 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EAU81954.1 - 0.83 10.1 7.1 0.37 11.2 2.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 EAU81955.1 - 3.7e-38 131.4 0.0 1.4e-37 129.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU81955.1 - 2e-19 69.9 0.0 1.5e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EAU81955.1 - 0.00036 20.0 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAU81955.1 - 0.058 12.7 0.0 0.9 8.8 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Glyco_hydro_3_C PF01915.22 EAU81960.2 - 3.1e-44 151.4 0.0 4.3e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAU81960.2 - 1.9e-31 109.6 0.0 3e-25 89.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAU81960.2 - 4.6e-19 68.3 0.0 8.1e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PAN_4 PF14295.6 EAU81962.1 - 0.045 13.7 1.0 0.082 12.8 1.0 1.5 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 EAU81963.1 - 0.068 13.1 1.9 0.14 12.1 1.9 1.6 1 0 0 1 1 1 0 PAN domain DUF1691 PF07950.11 EAU81964.1 - 4.1e-08 33.9 0.0 2.5e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) PsbX PF06596.11 EAU81964.1 - 0.8 9.8 4.8 1 9.4 0.1 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) E1-E2_ATPase PF00122.20 EAU81965.2 - 2.2e-32 112.1 2.9 4.4e-28 98.0 0.6 3.4 2 1 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAU81965.2 - 5.3e-26 91.5 14.3 9.6e-20 71.0 0.4 3.8 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EAU81965.2 - 2.8e-18 65.8 0.0 6.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAU81965.2 - 3e-15 57.1 0.0 1.8e-14 54.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAU81965.2 - 6.6e-15 54.5 0.0 1.6e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAU81965.2 - 7.7e-05 22.5 1.6 0.0072 16.1 1.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2269 PF10027.9 EAU81965.2 - 0.26 11.4 5.9 3.7 7.6 0.0 3.4 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) MARVEL PF01284.23 EAU81965.2 - 5.5 7.0 11.0 0.14 12.1 1.2 2.6 2 0 0 2 2 2 0 Membrane-associating domain DUF4131 PF13567.6 EAU81965.2 - 6.1 6.5 13.8 0.53 9.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3087 PF11286.8 EAU81965.2 - 6.5 6.2 5.5 30 4.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) ABC2_membrane PF01061.24 EAU81966.2 - 1e-37 129.7 17.2 1e-37 129.7 17.2 2.7 4 0 0 4 4 3 1 ABC-2 type transporter ABC_tran PF00005.27 EAU81966.2 - 8.1e-25 87.9 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EAU81966.2 - 0.00029 20.1 26.5 0.00029 20.1 26.5 2.1 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EAU81966.2 - 0.00065 19.6 0.1 0.0015 18.5 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EAU81966.2 - 0.013 15.3 1.5 0.095 12.5 0.3 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAU81966.2 - 0.021 14.6 0.2 0.052 13.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EAU81966.2 - 0.028 14.4 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 EAU81966.2 - 0.048 14.1 0.5 0.083 13.4 0.5 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU81966.2 - 0.054 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAU81966.2 - 0.08 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EAU81966.2 - 0.14 12.6 0.1 0.47 10.9 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EAU81966.2 - 0.19 11.9 1.0 0.36 11.1 1.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU81966.2 - 0.2 11.2 0.2 0.44 10.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU81966.2 - 0.24 12.0 0.0 0.43 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAU81966.2 - 0.26 11.0 0.6 0.42 10.3 0.6 1.3 1 0 0 1 1 1 0 AAA domain Cerato-platanin PF07249.12 EAU81968.1 - 7.8e-40 135.7 0.7 9.2e-40 135.5 0.7 1.0 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 EAU81969.2 - 5e-46 155.7 0.2 5.9e-46 155.4 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin F-box PF00646.33 EAU81970.1 - 2.1e-09 37.0 0.1 6.2e-09 35.5 0.0 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAU81970.1 - 7.7e-07 28.9 0.1 2.3e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU81970.1 - 0.0015 18.4 0.1 0.0035 17.2 0.1 1.6 1 0 0 1 1 1 1 F-box Elongin_A PF06881.11 EAU81970.1 - 0.23 12.0 3.0 1 9.9 0.0 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 EAU81971.2 - 1.7e-05 24.6 0.1 5.4e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU81971.2 - 0.00036 20.4 0.0 0.00085 19.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU81971.2 - 0.088 12.7 0.2 0.32 10.9 0.2 2.0 1 0 0 1 1 1 0 F-box LIM PF00412.22 EAU81971.2 - 0.35 11.1 4.4 1.9 8.8 0.0 3.4 3 0 0 3 3 3 0 LIM domain Hydrophobin PF01185.18 EAU81972.1 - 6.3e-26 90.8 13.1 7.6e-26 90.6 13.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin VCBS PF13517.6 EAU81973.2 - 1e-25 90.0 14.9 4.3e-08 33.6 0.0 5.3 3 3 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EAU81973.2 - 0.00037 20.6 18.1 0.55 10.4 0.0 6.1 7 0 0 7 7 7 4 FG-GAP repeat Itfg2 PF15907.5 EAU81973.2 - 0.014 14.4 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 p450 PF00067.22 EAU81974.2 - 2.6e-67 227.6 0.1 1.5e-65 221.7 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 Med25_VWA PF11265.8 EAU81974.2 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A MFS_1 PF07690.16 EAU81975.2 - 1.6e-26 93.1 28.8 2.2e-26 92.6 28.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EAU81975.2 - 2.2e-06 26.4 3.4 3.9e-06 25.6 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAU81975.2 - 0.00017 20.6 13.2 0.00017 20.6 13.2 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter Furin-like_2 PF15913.5 EAU81977.1 - 1.9e-07 31.2 31.3 2.4e-07 30.9 9.5 7.4 1 1 6 7 7 7 4 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 EAU81977.1 - 0.0056 17.0 8.9 0.0056 17.0 8.9 11.6 9 4 2 11 11 11 2 EGF-like domain Laminin_EGF PF00053.24 EAU81977.1 - 0.0084 16.2 19.3 0.0084 16.2 19.3 9.8 2 1 4 6 6 6 1 Laminin EGF domain DUF4381 PF14316.6 EAU81977.1 - 0.17 12.1 1.4 0.3 11.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2236 PF09995.9 EAU81978.2 - 2.1e-06 28.1 1.3 1e-05 25.9 0.2 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) MA3 PF02847.17 EAU81980.2 - 2.6e-26 91.8 0.2 5e-26 90.9 0.2 1.5 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 EAU81980.2 - 1.5e-10 41.1 3.1 1.7e-10 40.9 0.1 2.3 2 1 0 2 2 2 1 MIF4G domain DUF4505 PF14956.6 EAU81983.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) PP2C PF00481.21 EAU81984.2 - 2.8e-17 63.2 0.0 7.2e-14 52.0 0.0 3.3 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 EAU81984.2 - 0.039 13.9 0.0 12 5.7 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) F-box-like PF12937.7 EAU81985.2 - 0.035 14.0 6.5 0.037 13.9 2.9 3.0 2 1 0 2 2 2 0 F-box-like F-box-like PF12937.7 EAU81987.1 - 2.5e-05 24.1 3.8 3.9e-05 23.4 0.9 2.7 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU81987.1 - 0.21 12.1 0.4 12 6.5 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DDOST_48kD PF03345.14 EAU81990.1 - 4.5e-125 417.8 0.0 5.5e-125 417.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta XPA_C PF05181.12 EAU81990.1 - 0.0097 15.8 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus SID-1_RNA_chan PF13965.6 EAU81991.1 - 0.17 10.2 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HemY_N PF07219.13 EAU81991.1 - 0.23 11.7 0.8 0.44 10.8 0.3 1.5 1 1 0 1 1 1 0 HemY protein N-terminus Peptidase_S10 PF00450.22 EAU81994.2 - 9.9e-117 390.9 0.0 1.3e-116 390.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF357 PF04010.13 EAU81994.2 - 0.09 12.9 0.1 2.4 8.3 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF357) Calcipressin PF04847.12 EAU81995.1 - 9e-34 116.8 0.0 9e-34 116.8 0.0 1.8 2 0 0 2 2 2 1 Calcipressin RRM_1 PF00076.22 EAU81995.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ccdc124 PF06244.12 EAU81996.2 - 1.5e-26 93.4 20.1 1.5e-26 93.4 20.1 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 MFS_1 PF07690.16 EAU81997.2 - 2e-29 102.6 17.3 2.7e-29 102.2 17.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU81997.2 - 2.2e-08 33.4 5.4 2.4e-07 30.0 5.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3995 PF13160.6 EAU81997.2 - 1.7 9.0 12.0 0.069 13.5 3.7 2.8 3 1 0 4 4 4 0 Protein of unknown function (DUF3995) CDC73_C PF05179.14 EAU82000.1 - 2.3e-54 183.3 1.0 3.8e-54 182.6 1.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EAU82000.1 - 2.9e-07 30.1 0.0 0.013 14.9 0.0 2.2 2 0 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal SSP160 PF06933.11 EAU82000.1 - 0.00098 17.5 0.3 0.0014 17.0 0.3 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 F-box PF00646.33 EAU82002.2 - 8e-07 28.8 0.1 2.5e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU82002.2 - 0.0018 18.2 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like EH_Signature PF15611.6 EAU82002.2 - 0.035 13.5 2.6 0.06 12.8 2.6 1.3 1 0 0 1 1 1 0 EH_Signature domain F-box_4 PF15966.5 EAU82002.2 - 0.095 12.6 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 F-box DUF3138 PF11336.8 EAU82002.2 - 0.19 10.3 0.1 0.28 9.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Hydrophobin PF01185.18 EAU82003.1 - 2.1e-26 92.3 11.8 2.5e-26 92.1 11.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Dor1 PF04124.12 EAU82004.2 - 0.00077 18.2 10.7 0.006 15.3 8.9 2.1 1 1 1 2 2 2 2 Dor1-like family HOOK PF05622.12 EAU82004.2 - 0.0019 16.4 18.6 0.0025 16.1 18.6 1.1 1 0 0 1 1 1 1 HOOK protein Fmp27_WPPW PF10359.9 EAU82004.2 - 0.0072 15.2 12.6 0.01 14.7 12.6 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain AIP3 PF03915.13 EAU82004.2 - 0.0084 15.2 10.0 0.01 15.0 10.0 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 GAS PF13851.6 EAU82004.2 - 0.011 15.1 20.8 0.014 14.7 20.1 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prominin PF05478.11 EAU82004.2 - 0.016 13.2 9.2 0.02 12.9 9.2 1.1 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.9 EAU82004.2 - 0.028 14.7 1.4 0.028 14.7 1.4 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMCO5 PF14992.6 EAU82004.2 - 0.047 13.3 11.3 0.073 12.6 11.3 1.3 1 0 0 1 1 1 0 TMCO5 family Sec2p PF06428.11 EAU82004.2 - 0.049 13.6 14.7 0.16 11.9 12.6 2.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p FUSC PF04632.12 EAU82004.2 - 0.054 12.0 13.1 0.064 11.8 13.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MerR-DNA-bind PF09278.11 EAU82004.2 - 0.061 13.9 14.6 0.098 13.2 1.8 3.1 2 1 2 4 4 3 0 MerR, DNA binding NPV_P10 PF05531.12 EAU82004.2 - 0.071 13.6 5.9 5.3 7.6 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Dzip-like_N PF13815.6 EAU82004.2 - 0.072 13.1 14.1 0.05 13.6 2.7 2.3 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Med10 PF09748.9 EAU82004.2 - 0.091 12.7 4.6 1.6 8.7 1.1 2.4 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex ATG16 PF08614.11 EAU82004.2 - 0.094 12.9 26.3 0.55 10.4 24.2 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EAU82004.2 - 0.1 11.5 21.3 0.15 10.9 20.7 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EAU82004.2 - 0.14 12.3 10.3 1.6 8.9 2.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.10 EAU82004.2 - 0.25 11.4 9.2 1.2 9.2 1.3 2.1 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF2205 PF10224.9 EAU82004.2 - 0.38 10.8 9.7 0.17 11.9 1.5 2.6 2 2 0 2 2 2 0 Short coiled-coil protein DASH_Dam1 PF08653.10 EAU82004.2 - 0.63 9.9 3.7 21 5.0 0.9 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Spectrin PF00435.21 EAU82004.2 - 0.86 10.1 15.0 2.2 8.8 4.8 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.12 EAU82004.2 - 0.87 9.6 9.3 0.57 10.2 4.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CLZ PF16526.5 EAU82004.2 - 0.88 10.0 13.9 3.5 8.0 3.6 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TMF_DNA_bd PF12329.8 EAU82004.2 - 0.96 9.5 13.3 0.2 11.7 5.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DASH_Hsk3 PF08227.11 EAU82004.2 - 0.96 9.9 12.3 1.8 9.0 1.9 3.4 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like Phage_lysozyme2 PF18013.1 EAU82004.2 - 0.99 9.4 5.1 0.89 9.6 2.9 1.9 1 1 1 2 2 2 0 Phage tail lysozyme Spc24 PF08286.11 EAU82004.2 - 1.1 9.5 16.9 1.9 8.8 6.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.7 EAU82004.2 - 1.2 9.3 23.7 1.9 8.7 9.5 2.2 1 1 2 3 3 3 0 Tropomyosin like Sec34 PF04136.15 EAU82004.2 - 1.3 8.9 10.6 0.87 9.5 3.8 2.3 1 1 1 2 2 2 0 Sec34-like family DUF812 PF05667.11 EAU82004.2 - 1.3 7.8 19.3 2.4 6.9 19.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) RF-1 PF00472.20 EAU82004.2 - 1.4 8.8 15.2 0.019 14.9 2.8 2.2 1 1 1 2 2 2 0 RF-1 domain DivIC PF04977.15 EAU82004.2 - 1.9 8.3 19.3 1.1 9.0 1.4 3.4 1 1 2 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.19 EAU82004.2 - 2.7 5.8 9.5 3.6 5.4 9.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.6 EAU82004.2 - 2.7 8.2 26.8 5.8 7.1 11.0 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HAUS-augmin3 PF14932.6 EAU82004.2 - 3.3 7.2 20.9 3.9 7.0 8.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 EAU82004.2 - 5.1 7.8 15.9 9 7.0 5.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 EAU82004.2 - 6.4 6.6 16.9 1.5 8.6 10.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EAU82004.2 - 7.2 6.7 19.7 3.5 7.7 11.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EAU82004.2 - 7.8 7.0 25.9 5.8 7.5 11.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 EAU82004.2 - 8.3 4.9 10.7 13 4.2 2.9 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A WXG100 PF06013.12 EAU82004.2 - 9.6 6.5 12.8 4 7.7 2.8 3.2 2 2 1 4 4 3 0 Proteins of 100 residues with WXG FlxA PF14282.6 EAU82004.2 - 9.8 6.2 16.9 39 4.3 13.8 2.5 2 1 0 2 2 1 0 FlxA-like protein JSRP PF15312.6 EAU82005.1 - 0.75 9.8 12.4 15 5.6 0.2 4.3 1 1 3 4 4 4 0 Junctional sarcoplasmic reticulum protein tRNA-synt_1b PF00579.25 EAU82006.2 - 4.1e-75 252.8 0.0 5e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 EAU82006.2 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) F-box-like PF12937.7 EAU82007.1 - 2.8e-07 30.3 0.0 1.1e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 F-box-like APG6_N PF17675.1 EAU82007.1 - 0.0059 17.1 2.6 0.01 16.4 2.6 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF3287 PF11690.8 EAU82007.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) CCDC-167 PF15188.6 EAU82007.1 - 0.28 11.6 1.1 0.73 10.2 1.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF349 PF03993.12 EAU82007.1 - 0.56 10.5 2.5 1.1 9.6 2.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) F-box-like PF12937.7 EAU82008.1 - 0.048 13.5 0.3 0.17 11.8 0.3 2.0 1 0 0 1 1 1 0 F-box-like Cellulase PF00150.18 EAU82009.1 - 8.9e-12 45.0 0.0 7.4e-09 35.4 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EAU82009.1 - 2.6e-06 27.9 0.0 6.7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain F-box-like PF12937.7 EAU82011.2 - 7.3e-05 22.6 0.1 0.00021 21.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like Glyco_transf_28 PF03033.20 EAU82012.2 - 5.5e-20 71.8 0.4 5.5e-19 68.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EAU82012.2 - 0.00037 19.4 0.2 0.0007 18.5 0.2 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF2870 PF11069.8 EAU82012.2 - 0.27 11.7 2.1 0.62 10.5 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) PRANC PF09372.10 EAU82014.1 - 0.00021 21.6 0.0 0.00052 20.3 0.0 1.7 1 0 0 1 1 1 1 PRANC domain F-box PF00646.33 EAU82014.1 - 0.0038 17.1 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU82014.1 - 0.019 14.9 0.1 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 F-box-like Dioxygenase_C PF00775.21 EAU82014.1 - 0.066 12.6 0.6 0.11 11.9 0.6 1.3 1 0 0 1 1 1 0 Dioxygenase DUF553 PF04473.12 EAU82015.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like domain GHL13 PF14883.6 EAU82015.1 - 0.044 12.8 1.9 0.16 11.0 1.5 1.8 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 13 PIF1 PF05970.14 EAU82018.2 - 2.6e-30 105.8 0.0 3.8e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EAU82018.2 - 2.5e-13 50.7 0.4 3.7e-12 46.9 0.0 2.5 1 1 1 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAU82018.2 - 4.4e-12 46.1 0.0 1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU82018.2 - 0.00014 22.2 0.0 0.00039 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU82018.2 - 0.0012 19.2 1.2 0.11 12.9 0.0 3.6 2 2 2 4 4 4 1 AAA ATPase domain POTRA_TamA_1 PF17243.2 EAU82018.2 - 0.0068 16.5 0.0 0.029 14.4 0.0 2.1 2 0 0 2 2 2 1 POTRA domain TamA domain 1 Herpes_Helicase PF02689.14 EAU82018.2 - 0.0078 14.2 0.0 0.012 13.5 0.0 1.2 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 EAU82018.2 - 0.097 12.4 2.4 0.59 9.8 0.0 3.2 4 1 0 4 4 4 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 EAU82018.2 - 0.18 11.0 0.1 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Alpha_kinase PF02816.18 EAU82028.2 - 2.2e-24 86.6 0.0 3.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family zinc-ribbons_6 PF07191.12 EAU82028.2 - 1.3 9.1 5.6 3.5 7.7 5.6 1.7 1 0 0 1 1 1 0 zinc-ribbons TackOD1 PF18551.1 EAU82028.2 - 2.5 7.8 7.5 1.5 8.5 1.1 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 KxDL PF10241.9 EAU82033.2 - 0.0015 18.8 1.2 0.0017 18.6 1.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein MEIOC PF15189.6 EAU82033.2 - 0.015 14.9 0.6 0.016 14.8 0.6 1.2 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC T6PP_N PF18572.1 EAU82033.2 - 0.038 13.8 0.3 0.041 13.7 0.3 1.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1664 PF07889.12 EAU82033.2 - 0.1 12.7 1.1 0.13 12.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Med9 PF07544.13 EAU82033.2 - 0.11 12.6 1.4 0.15 12.1 1.4 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Rad60-SLD_2 PF13881.6 EAU82036.1 - 6.8e-12 45.5 0.0 1.1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAU82036.1 - 0.15 11.8 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family SPX PF03105.19 EAU82036.1 - 3.3 7.5 7.0 4.3 7.2 7.0 1.3 1 0 0 1 1 1 0 SPX domain CDK2AP PF09806.9 EAU82039.2 - 0.097 12.7 7.1 0.16 12.0 7.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Apt1 PF10351.9 EAU82039.2 - 2.1 7.1 7.9 2.7 6.8 7.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EAU82039.2 - 5.8 5.4 10.1 7.5 5.0 10.1 1.1 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 EAU82040.2 - 1.8e-30 106.1 28.2 4.6e-30 104.7 28.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Iron_permease PF04120.12 EAU82040.2 - 0.075 12.8 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Low affinity iron permease Trp_oprn_chp PF09534.10 EAU82040.2 - 0.27 11.0 1.8 0.37 10.6 0.0 2.1 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MMPL PF03176.15 EAU82040.2 - 1 8.2 5.7 1 8.3 1.0 2.4 2 0 0 2 2 2 0 MMPL family Pkinase_fungal PF17667.1 EAU82041.1 - 6.6e-49 166.8 2.7 1.9e-29 102.7 0.0 2.6 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 EAU82041.1 - 0.031 14.2 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAU82044.1 - 1.1e-36 126.6 0.5 3.3e-21 75.5 0.0 3.5 2 2 1 3 3 3 2 Fungal protein kinase adh_short PF00106.25 EAU82046.1 - 2.1e-15 56.7 0.4 3.2e-07 30.0 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU82046.1 - 2.6e-07 30.4 0.7 0.052 13.1 0.2 3.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Caudo_TAP PF02413.17 EAU82046.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK NAD_binding_7 PF13241.6 EAU82046.1 - 0.18 12.2 0.0 0.44 11.0 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Flot PF15975.5 EAU82049.1 - 0.12 12.6 1.7 0.37 11.0 1.7 1.8 1 0 0 1 1 1 0 Flotillin FliD_N PF02465.18 EAU82049.1 - 0.12 13.1 0.2 0.12 13.1 0.2 2.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus THUMP PF02926.17 EAU82049.1 - 0.23 11.6 5.3 16 5.5 3.5 2.8 2 1 1 3 3 3 0 THUMP domain PI3K_P85_iSH2 PF16454.5 EAU82049.1 - 0.64 9.6 12.1 0.36 10.4 2.2 2.8 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain KxDL PF10241.9 EAU82049.1 - 4.7 7.6 17.4 2 8.8 0.3 4.2 4 0 0 4 4 4 0 Uncharacterized conserved protein FUSC PF04632.12 EAU82049.1 - 5.6 5.4 9.0 5.4 5.4 5.2 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Prefoldin PF02996.17 EAU82049.1 - 7.6 6.5 13.1 6.3 6.7 4.6 3.5 3 0 0 3 3 3 0 Prefoldin subunit Plasmid_RAQPRD PF09686.10 EAU82049.1 - 9 6.6 9.4 0.84 9.9 1.5 3.0 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) BUD22 PF09073.10 EAU82050.1 - 0.012 15.0 8.2 0.012 14.9 8.2 1.1 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 EAU82050.1 - 0.76 9.1 8.8 1 8.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 EAU82050.1 - 4.1 5.5 19.4 5 5.2 19.4 1.0 1 0 0 1 1 1 0 Nop14-like family Citrate_bind PF16114.5 EAU82052.2 - 4.7e-90 299.8 0.0 7.9e-90 299.1 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 EAU82052.2 - 1.5e-19 70.3 0.1 5.1e-17 62.0 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EAU82052.2 - 1.9e-15 57.0 0.0 4.5e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EAU82052.2 - 7.7e-12 45.7 0.0 2.1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 EAU82052.2 - 5.4e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 EAU82052.2 - 1.3e-05 25.0 0.0 5.7e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain PPP1R35_C PF15503.6 EAU82055.1 - 0.016 15.0 3.8 0.063 13.1 0.0 2.9 3 1 0 3 3 3 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Phage_min_cap2 PF06152.11 EAU82055.1 - 0.028 13.3 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF3618 PF12277.8 EAU82055.1 - 0.18 12.1 5.1 3.2 8.1 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DUF1216 PF06746.11 EAU82055.1 - 2 8.4 5.1 2.9 7.9 2.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1216) TFB6 PF17110.5 EAU82056.1 - 0.0033 17.2 0.6 0.0059 16.4 0.6 1.4 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH PTPRCAP PF15713.5 EAU82056.1 - 0.036 14.3 5.3 0.082 13.2 5.3 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Ribosomal_60s PF00428.19 EAU82056.1 - 0.2 12.3 6.0 0.54 10.9 6.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein RRN3 PF05327.11 EAU82056.1 - 0.5 8.9 6.4 10 4.5 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 EAU82056.1 - 0.61 9.5 11.1 0.18 11.2 7.9 1.7 2 0 0 2 2 2 0 SDA1 DNA_pol_phi PF04931.13 EAU82056.1 - 0.61 8.1 13.4 0.91 7.5 13.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EAU82056.1 - 0.93 7.6 10.7 0.39 8.9 7.3 1.8 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 EAU82056.1 - 2 7.7 10.1 4.1 6.7 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein GPI-anchored PF10342.9 EAU82057.2 - 0.0036 18.0 0.0 0.0051 17.5 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4148 PF13663.6 EAU82057.2 - 0.48 10.6 0.1 0.48 10.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) HrpB7 PF09486.10 EAU82058.2 - 0.01 16.2 1.7 0.01 16.2 1.7 3.7 3 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) Matrilin_ccoil PF10393.9 EAU82058.2 - 0.045 13.6 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4172 PF13776.6 EAU82058.2 - 0.076 13.4 0.6 1.5 9.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4172) IFT57 PF10498.9 EAU82058.2 - 0.14 11.1 8.0 1.5 7.7 0.1 3.2 3 1 0 3 3 3 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 EAU82058.2 - 0.23 11.5 2.2 8.6 6.4 0.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 EAU82058.2 - 0.8 9.7 4.4 0.23 11.5 0.9 1.9 2 0 0 2 2 2 0 FlxA-like protein COG5 PF10392.9 EAU82058.2 - 1.2 9.3 7.4 2 8.6 0.2 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 SlyX PF04102.12 EAU82058.2 - 1.4 9.6 5.4 3.3 8.4 0.1 3.6 4 0 0 4 4 4 0 SlyX NleF_casp_inhib PF16809.5 EAU82058.2 - 2.7 7.9 6.0 17 5.3 2.8 3.1 2 1 0 2 2 2 0 NleF caspase inhibitor Med21 PF11221.8 EAU82058.2 - 8.1 6.7 8.2 18 5.6 0.2 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex 2OG-FeII_Oxy_3 PF13640.6 EAU82059.1 - 5.3e-10 40.1 0.1 1.4e-09 38.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF3258 PF11646.8 EAU82059.1 - 0.074 13.2 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF3258 p450 PF00067.22 EAU82060.2 - 2.3e-34 118.9 0.0 5e-34 117.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU82062.2 - 3.6e-23 82.0 0.0 6.3e-23 81.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF563 PF04577.14 EAU82063.2 - 0.00069 19.8 0.0 0.002 18.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Laminin_II PF06009.12 EAU82063.2 - 0.007 16.4 3.8 0.22 11.6 0.1 2.9 2 1 1 3 3 3 2 Laminin Domain II NCKAP5 PF15246.6 EAU82063.2 - 0.015 14.9 5.3 0.026 14.1 5.3 1.3 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein MutS_III PF05192.18 EAU82063.2 - 0.6 10.3 2.6 0.52 10.5 0.8 1.7 2 0 0 2 2 2 0 MutS domain III KELK PF15796.5 EAU82064.1 - 0.0049 17.3 1.1 0.0049 17.3 1.1 4.6 4 1 0 5 5 5 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Syntaxin-6_N PF09177.11 EAU82064.1 - 0.014 16.0 12.9 0.57 10.8 3.1 3.9 3 1 0 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 EAU82064.1 - 0.11 12.9 3.7 36 4.9 0.2 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 EAU82064.1 - 0.17 12.0 4.7 1.7 8.8 0.0 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Occludin_ELL PF07303.13 EAU82064.1 - 0.37 11.5 13.2 6.1 7.6 0.1 4.2 4 2 1 5 5 5 0 Occludin homology domain Spc24 PF08286.11 EAU82064.1 - 0.78 10.0 11.1 8.2 6.7 0.2 4.0 3 1 1 5 5 5 0 Spc24 subunit of Ndc80 Pox_A_type_inc PF04508.12 EAU82064.1 - 2 8.4 6.7 0.54 10.2 1.9 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF5339 PF17274.2 EAU82064.1 - 2.9 8.8 6.6 11 6.9 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5339) DUF5320 PF17253.2 EAU82064.1 - 3.8 8.7 6.2 4.4 8.4 0.4 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5320) SGS PF05002.15 EAU82065.2 - 0.074 13.2 0.7 0.23 11.6 0.7 1.8 1 0 0 1 1 1 0 SGS domain EVI2A PF05399.11 EAU82065.2 - 0.5 9.9 1.8 1.1 8.7 1.8 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Cutinase PF01083.22 EAU82066.1 - 9e-43 146.3 0.0 1e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 EAU82066.1 - 2.3e-05 24.3 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.11 EAU82066.1 - 6.5e-05 22.6 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 EAU82066.1 - 0.0099 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) VirJ PF06057.11 EAU82066.1 - 0.025 14.5 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 EAU82066.1 - 0.13 12.1 0.5 0.44 10.4 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EAU82066.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NEMO PF11577.8 EAU82067.1 - 0.21 11.6 0.4 6.9 6.8 0.1 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO F-box-like PF12937.7 EAU82068.1 - 0.0019 18.0 0.0 0.0078 16.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like VGPC1_C PF16799.5 EAU82068.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Fanconi_A PF03511.14 EAU82068.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Fanconi anaemia group A protein DUF3915 PF13054.6 EAU82069.2 - 0.79 9.7 2.4 1.8 8.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Nop53 PF07767.11 EAU82069.2 - 2.8 7.2 9.9 4.6 6.5 9.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.25 EAU82071.2 - 2.4e-09 36.9 0.0 1.9e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU82071.2 - 0.1 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Zn_clus PF00172.18 EAU82075.2 - 1 9.5 9.4 3.6 7.8 0.9 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 EAU82075.2 - 1.1 9.8 5.6 3.9 8.0 5.7 1.8 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region BPS PF08947.10 EAU82076.1 - 0.13 12.1 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 BPS (Between PH and SH2) zf-A20 PF01754.16 EAU82077.1 - 0.77 9.8 2.5 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 A20-like zinc finger Helitron_like_N PF14214.6 EAU82081.2 - 2.8e-11 44.0 0.0 4.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAU82082.1 - 7.9e-07 28.6 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU82082.1 - 4.8e-05 23.1 0.0 9.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EAU82082.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EAU82082.1 - 0.023 15.0 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EAU82082.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein UPF0565 PF10561.9 EAU82086.2 - 0.071 12.3 0.0 0.082 12.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 MFS_1 PF07690.16 EAU82087.2 - 2.3e-18 66.2 27.6 2.3e-18 66.2 27.6 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 EAU82087.2 - 3.5 5.8 19.4 0.04 12.2 4.8 3.3 2 2 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family HpcH_HpaI PF03328.14 EAU82088.1 - 3.7e-28 98.2 0.0 3.8e-27 94.9 0.0 1.9 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 EAU82088.1 - 0.046 13.2 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase PK PF00224.21 EAU82088.1 - 0.056 12.3 0.0 2.8 6.8 0.0 2.0 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain adh_short_C2 PF13561.6 EAU82090.2 - 6e-27 94.7 2.8 4.9e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU82090.2 - 6.8e-20 71.4 1.6 2e-13 50.2 0.8 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EAU82090.2 - 0.0039 17.1 0.1 0.0068 16.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Peroxin-13_N PF04088.13 EAU82091.1 - 1.4e-44 151.9 0.0 1.9e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EAU82091.1 - 8.9e-11 41.3 0.0 2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAU82091.1 - 2.8e-09 36.4 1.8 0.0036 16.9 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EAU82091.1 - 4.4e-08 32.9 0.1 8.6e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3915 PF13054.6 EAU82092.2 - 2.1 8.3 6.1 6.3 6.8 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Pkinase_fungal PF17667.1 EAU82093.2 - 6e-55 186.7 0.0 1.2e-54 185.7 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU82093.2 - 4.5e-05 23.0 0.1 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU82093.2 - 0.00044 20.2 2.7 0.0005 20.1 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAU82093.2 - 0.16 11.5 0.1 0.47 10.0 0.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase KDZ PF18758.1 EAU82094.1 - 1.8e-44 152.0 0.0 2.9e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 EAU82094.1 - 4.2e-11 43.1 0.0 8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 EAU82094.1 - 2.7e-08 33.9 0.1 5.6e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU82094.1 - 0.006 16.7 0.2 0.014 15.5 0.2 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF276 PF03434.13 EAU82095.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 DUF276 AMP-binding_C PF13193.6 EAU82098.1 - 0.21 12.6 2.6 0.56 11.2 1.0 2.1 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain DUF550 PF04447.12 EAU82099.2 - 0.023 14.8 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) BUD22 PF09073.10 EAU82099.2 - 1.3 8.3 6.4 1.7 7.9 6.4 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EAU82099.2 - 2.9 5.9 10.8 3.7 5.5 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EAU82099.2 - 6.3 4.9 7.5 8.7 4.4 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase_fungal PF17667.1 EAU82101.2 - 2.4e-57 194.6 0.0 6.3e-57 193.2 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU82101.2 - 0.0004 19.8 0.0 0.0009 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU82101.2 - 0.01 15.8 0.3 0.035 14.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sel_put PF04328.13 EAU82102.2 - 0.017 15.1 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Selenoprotein, putative WD40 PF00400.32 EAU82103.2 - 2.3e-132 427.0 33.1 1.2e-09 38.6 0.1 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82103.2 - 2.1e-73 242.6 0.0 9.9e-05 22.6 0.0 14.4 1 1 13 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU82103.2 - 3.8e-32 111.6 16.7 0.013 14.4 0.0 13.8 1 1 13 14 14 14 10 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAU82103.2 - 2.8e-19 68.5 20.2 0.33 10.9 0.0 14.0 14 0 0 14 14 14 3 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EAU82103.2 - 1.7e-11 44.4 4.4 0.046 13.5 0.0 8.6 1 1 6 8 8 8 4 Lipoprotein LpqB beta-propeller domain Frtz PF11768.8 EAU82103.2 - 3.5e-09 35.5 0.0 0.79 8.0 0.0 7.4 2 1 8 10 10 10 2 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 EAU82103.2 - 1.8e-08 34.5 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF374 PF04028.13 EAU82103.2 - 3.9e-08 32.7 1.1 28 4.3 0.0 8.3 6 1 3 9 9 9 0 Domain of unknown function (DUF374) WD40_like PF17005.5 EAU82103.2 - 6.1e-07 29.0 0.0 56 2.9 0.0 8.8 6 4 4 11 11 11 0 WD40-like domain AAA_16 PF13191.6 EAU82103.2 - 3.9e-05 24.1 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.6 EAU82103.2 - 4.4e-05 23.2 1.0 4.5 6.8 0.1 4.3 1 1 2 3 3 3 3 PQQ-like domain Nbas_N PF15492.6 EAU82103.2 - 6.8e-05 22.3 7.0 1.9 7.7 0.0 7.4 3 2 7 10 10 10 2 Neuroblastoma-amplified sequence, N terminal KAP_NTPase PF07693.14 EAU82103.2 - 0.0029 16.9 0.6 0.073 12.3 0.1 2.5 2 1 1 3 3 3 1 KAP family P-loop domain Peptidase_S9_N PF02897.15 EAU82103.2 - 0.0047 15.8 0.0 24 3.6 0.0 4.9 3 2 1 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain potato_inhibit PF00280.18 EAU82103.2 - 0.0051 17.4 0.0 40 5.0 0.0 5.1 6 1 1 7 7 3 0 Potato inhibitor I family AAA_22 PF13401.6 EAU82103.2 - 0.0056 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.16 EAU82103.2 - 0.013 14.1 0.2 0.41 9.1 0.0 3.5 2 1 2 5 5 5 0 Cytochrome D1 heme domain WD40_3 PF15911.5 EAU82103.2 - 0.014 15.3 0.0 30 4.7 0.0 5.9 7 0 0 7 7 6 0 WD domain, G-beta repeat PQQ PF01011.21 EAU82103.2 - 0.017 15.1 0.4 0.62 10.1 0.1 3.6 3 0 0 3 3 3 0 PQQ enzyme repeat AAA_7 PF12775.7 EAU82103.2 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EAU82103.2 - 0.058 13.5 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4684 PF15736.5 EAU82103.2 - 0.067 11.9 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) RNA_helicase PF00910.22 EAU82103.2 - 0.11 12.9 0.0 0.45 10.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Arch_fla_DE PF04659.13 EAU82103.2 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 1 0 0 1 1 1 0 Archaeal flagella protein DUF4596 PF15363.6 EAU82103.2 - 1 9.6 22.0 21 5.5 0.0 9.0 11 0 0 11 11 10 0 Domain of unknown function (DUF4596) PQQ_3 PF13570.6 EAU82103.2 - 1.9 9.1 7.9 9.2 6.9 0.9 5.0 6 0 0 6 6 3 0 PQQ-like domain CHAT PF12770.7 EAU82104.2 - 2.8e-26 92.6 0.0 5e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 CHAT domain Hydrolase PF00702.26 EAU82104.2 - 0.0053 17.1 0.1 0.0088 16.3 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Mob1_phocein PF03637.17 EAU82105.1 - 1.6e-25 90.0 0.0 2.5e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Hva1_TUDOR PF11160.8 EAU82110.2 - 5.1e-14 52.2 3.1 5.1e-14 52.2 3.1 3.5 4 0 0 4 4 4 1 Hypervirulence associated proteins TUDOR domain DUF2097 PF09870.9 EAU82110.2 - 0.012 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) Pro_isomerase PF00160.21 EAU82113.1 - 1.2e-48 165.4 0.4 1.3e-48 165.3 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AA_permease_2 PF13520.6 EAU82114.2 - 1.2e-67 228.6 29.5 1.2e-67 228.6 29.5 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAU82114.2 - 1e-16 60.6 22.9 1.5e-16 60.1 22.9 1.2 1 0 0 1 1 1 1 Amino acid permease Dioxygenase_C PF00775.21 EAU82116.2 - 1e-44 152.2 0.0 1.5e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EAU82116.2 - 2.2e-32 110.7 0.0 3.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EAU82116.2 - 0.00023 21.4 0.1 0.003 17.8 0.0 2.6 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF2075 PF09848.9 EAU82117.2 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF563 PF04577.14 EAU82118.2 - 4.4e-22 79.2 0.1 1.3e-21 77.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) KDZ PF18758.1 EAU82120.2 - 2.2e-50 171.3 0.0 6.5e-50 169.8 0.0 1.9 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU82120.2 - 4.7e-31 107.1 0.2 1.3e-30 105.7 0.2 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU82120.2 - 1.6e-09 37.8 0.1 4.8e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU82120.2 - 6.5e-07 29.2 0.0 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases DUF563 PF04577.14 EAU82121.2 - 3.3e-21 76.4 0.1 1.7e-20 74.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Hva1_TUDOR PF11160.8 EAU82122.1 - 2.7e-13 49.8 2.4 3.4e-13 49.5 2.4 1.1 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain CSN5_C PF18323.1 EAU82123.2 - 1.3e-30 106.2 2.8 2.5e-30 105.2 2.8 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 EAU82123.2 - 5.9e-26 90.8 0.1 1.4e-25 89.6 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EAU82123.2 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Amidase PF01425.21 EAU82124.2 - 7.1e-74 249.4 0.0 2.1e-73 247.8 0.0 1.7 1 1 0 1 1 1 1 Amidase UPF0180 PF03698.13 EAU82124.2 - 0.2 11.9 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) DUF3328 PF11807.8 EAU82125.1 - 9.4e-18 64.8 0.0 1.4e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EAU82127.2 - 1.1e-18 67.9 0.1 1.3e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Flagellin_N PF00669.20 EAU82128.1 - 0.089 12.9 1.5 0.14 12.3 1.5 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FHA PF00498.26 EAU82129.1 - 2.7e-13 50.1 0.0 4.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAU82129.1 - 6.2e-07 29.6 0.0 3.4e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Ribonucleas_3_3 PF14622.6 EAU82130.1 - 5.1e-13 49.3 0.0 7.3e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like WD40 PF00400.32 EAU82131.1 - 2.4e-104 338.3 16.6 9.4e-11 42.1 0.0 11.0 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82131.1 - 1.3e-54 182.4 0.0 0.00032 20.9 0.0 10.4 1 1 9 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU82131.1 - 1.6e-21 76.6 6.1 1.5 7.7 0.0 10.5 3 1 8 11 11 11 10 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAU82131.1 - 1.1e-17 63.4 24.8 2.4 8.2 0.0 12.3 12 0 0 12 12 12 8 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EAU82131.1 - 9.4e-14 51.8 9.4 0.00053 19.8 0.0 7.3 3 1 6 9 9 9 6 Lipoprotein LpqB beta-propeller domain NACHT PF05729.12 EAU82131.1 - 9.2e-10 38.7 0.0 1.9e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF374 PF04028.13 EAU82131.1 - 1.1e-07 31.3 6.2 4 7.1 0.0 7.9 2 1 7 9 9 8 1 Domain of unknown function (DUF374) AAA_16 PF13191.6 EAU82131.1 - 1.8e-07 31.7 0.1 5.1e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain CHAP PF05257.16 EAU82131.1 - 6.1e-07 29.9 1.9 3.2 8.4 0.0 6.9 2 2 6 8 8 8 1 CHAP domain WD40_like PF17005.5 EAU82131.1 - 5e-06 26.1 0.0 72 2.6 0.0 7.5 5 3 4 9 9 9 0 WD40-like domain Frtz PF11768.8 EAU82131.1 - 6.2e-05 21.5 0.0 19 3.4 0.0 5.7 1 1 6 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4596 PF15363.6 EAU82131.1 - 7.2e-05 22.9 20.2 9.3 6.6 0.2 9.1 9 0 0 9 9 9 1 Domain of unknown function (DUF4596) Peptidase_S9_N PF02897.15 EAU82131.1 - 0.00027 19.9 0.1 38 2.9 0.0 6.3 1 1 5 6 6 6 0 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_22 PF13401.6 EAU82131.1 - 0.0011 19.3 0.0 0.0042 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 EAU82131.1 - 0.0013 18.0 1.8 0.0048 16.2 0.3 2.0 1 1 1 2 2 2 1 KAP family P-loop domain APS_kinase PF01583.20 EAU82131.1 - 0.035 14.0 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Arch_fla_DE PF04659.13 EAU82131.1 - 0.14 12.1 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal flagella protein AAA_18 PF13238.6 EAU82131.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 EAU82133.2 - 1.6e-59 201.8 0.0 4.5e-59 200.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU82133.2 - 0.00046 19.6 0.0 0.00098 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU82133.2 - 0.028 14.4 2.0 0.031 14.2 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family ATP-cone PF03477.16 EAU82133.2 - 0.25 11.9 0.6 5.2 7.7 0.1 3.1 3 0 0 3 3 3 0 ATP cone domain DUF4983 PF16356.5 EAU82136.2 - 0.034 15.0 0.1 0.061 14.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4983) Ammonium_transp PF00909.21 EAU82143.2 - 6.5e-113 377.4 33.5 7.3e-106 354.2 24.3 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family PLAC8 PF04749.17 EAU82149.2 - 2.3e-17 63.8 0.2 3.5e-17 63.2 0.2 1.3 1 0 0 1 1 1 1 PLAC8 family Ammonium_transp PF00909.21 EAU82151.2 - 1e-106 357.0 28.4 6.3e-58 196.4 15.3 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family WD40 PF00400.32 EAU82152.2 - 8e-62 203.7 26.3 6.2e-10 39.5 0.2 8.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82152.2 - 2.7e-30 104.5 0.1 0.001 19.3 0.0 7.5 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU82152.2 - 2.6e-15 56.2 3.0 0.11 11.5 0.0 7.1 1 1 6 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 EAU82152.2 - 7.7e-10 38.9 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.12 EAU82152.2 - 3.5e-08 33.2 14.4 6.1 6.9 0.0 8.3 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 EAU82152.2 - 1e-07 32.5 0.2 2.6e-07 31.2 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU82152.2 - 0.00055 20.2 0.0 0.0027 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Frtz PF11768.8 EAU82152.2 - 0.0006 18.3 0.0 0.99 7.6 0.0 3.6 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz KAP_NTPase PF07693.14 EAU82152.2 - 0.0016 17.7 2.1 0.0053 16.0 0.3 2.0 1 1 0 2 2 2 1 KAP family P-loop domain APS_kinase PF01583.20 EAU82152.2 - 0.034 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase WD40_like PF17005.5 EAU82152.2 - 0.093 12.0 0.0 19 4.4 0.0 3.9 2 2 4 6 6 6 0 WD40-like domain AAA_18 PF13238.6 EAU82152.2 - 0.12 12.9 0.0 0.41 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Helitron_like_N PF14214.6 EAU82153.2 - 8.2e-27 94.7 0.1 6.6e-26 91.7 0.0 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DUF3938 PF13074.6 EAU82153.2 - 0.033 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Dehydratase_SU PF02287.15 EAU82153.2 - 0.042 13.9 0.6 0.32 11.1 0.2 2.3 2 0 0 2 2 2 0 Dehydratase small subunit D-ser_dehydrat PF14031.6 EAU82157.2 - 0.098 13.3 0.0 0.18 12.5 0.0 1.6 1 1 0 1 1 1 0 Putative serine dehydratase domain DUF3696 PF12476.8 EAU82157.2 - 0.18 12.2 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) FAD_binding_4 PF01565.23 EAU82165.2 - 2e-23 82.6 1.2 3.8e-23 81.8 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU82165.2 - 4.5e-08 33.1 0.0 9.1e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DAP10 PF07213.11 EAU82165.2 - 0.15 12.0 0.2 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 DAP10 membrane protein Ras PF00071.22 EAU82166.2 - 5.7e-28 97.5 0.0 9.6e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Pkinase_Tyr PF07714.17 EAU82166.2 - 3.4e-23 82.3 0.0 1.4e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EAU82166.2 - 1.2e-22 80.5 0.0 1.4e-12 47.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Roc PF08477.13 EAU82166.2 - 7.7e-11 42.3 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU82166.2 - 0.00038 20.0 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EAU82166.2 - 0.0099 15.4 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EAU82166.2 - 0.033 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit VSP PF03302.13 EAU82167.2 - 0.061 12.2 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Herpes_gE PF02480.16 EAU82168.2 - 0.055 12.2 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PTP_tm PF18861.1 EAU82168.2 - 0.15 12.0 0.2 0.24 11.3 0.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adeno_E3_CR2 PF02439.15 EAU82168.2 - 0.21 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FMN_red PF03358.15 EAU82169.2 - 2.3e-08 33.9 0.1 2.9e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EAU82169.2 - 0.00091 19.0 0.1 0.0011 18.7 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EAU82170.1 - 3.5e-08 33.3 0.0 4.4e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EAU82170.1 - 1.5e-05 24.8 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EAU82170.1 - 0.00093 19.4 2.0 0.52 10.5 0.1 2.8 1 1 1 2 2 2 2 Flavodoxin AdoMet_MTase PF07757.13 EAU82171.1 - 5.6e-34 116.8 0.1 7.7e-33 113.2 0.1 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 EAU82171.1 - 0.0047 16.8 0.0 0.0081 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EAU82171.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAU82171.1 - 0.17 12.7 0.0 0.34 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Aldose_epim PF01263.20 EAU82172.2 - 2.1e-51 175.0 0.0 1.2e-49 169.3 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase IL13 PF03487.13 EAU82173.1 - 0.13 12.1 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Interleukin-13 DUF2749 PF10907.8 EAU82174.1 - 2.8e-05 24.2 0.0 0.00013 22.0 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2749) Sin_N PF04801.13 EAU82177.2 - 0.0012 18.1 4.2 0.0016 17.7 4.2 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Nop53 PF07767.11 EAU82177.2 - 0.18 11.2 16.9 0.26 10.6 16.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Ribosomal_L18A PF01775.17 EAU82178.1 - 1.3e-54 183.5 0.2 1.6e-54 183.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF2264 PF10022.9 EAU82182.2 - 3.4e-142 473.7 0.6 4.3e-142 473.4 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DUF202 PF02656.15 EAU82183.2 - 0.1 13.0 0.3 0.23 11.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PLAC8 PF04749.17 EAU82184.2 - 2.5e-27 95.8 13.7 3e-27 95.5 13.7 1.1 1 0 0 1 1 1 1 PLAC8 family HTH_21 PF13276.6 EAU82186.2 - 0.0049 17.0 0.1 2.1 8.5 0.0 2.5 2 0 0 2 2 2 2 HTH-like domain NepR PF18557.1 EAU82186.2 - 0.16 11.6 0.6 0.35 10.5 0.6 1.5 1 0 0 1 1 1 0 Anti-sigma factor NepR GST_N_2 PF13409.6 EAU82189.1 - 9.8e-12 45.0 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU82189.1 - 1.4e-10 41.4 0.0 2.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EAU82189.1 - 6.3e-09 36.1 0.0 1.3e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EAU82189.1 - 0.0022 18.2 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 EAU82189.1 - 0.0023 17.9 0.1 0.0056 16.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EAU82189.1 - 0.081 13.5 0.0 0.17 12.4 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_S8 PF00082.22 EAU82190.1 - 7.8e-29 100.9 25.2 2.1e-28 99.5 25.2 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAU82190.1 - 1.4e-06 28.9 0.0 0.00031 21.3 0.0 2.3 1 1 1 2 2 2 2 Peptidase inhibitor I9 F-box-like PF12937.7 EAU82193.1 - 0.0049 16.7 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like Suf PF05843.14 EAU82196.2 - 0.86 9.5 5.1 1.1 9.2 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Trypan_PARP PF05887.11 EAU82196.2 - 4.7 7.2 5.5 8.5 6.4 5.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trp_DMAT PF11991.8 EAU82198.2 - 4.3e-56 190.9 0.0 1.1e-55 189.6 0.0 1.6 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase MFS_1 PF07690.16 EAU82199.2 - 9.9e-38 130.0 26.5 9.9e-38 130.0 26.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_DMAT PF11991.8 EAU82200.1 - 2e-75 254.5 0.0 2.6e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Ricin_B_lectin PF00652.22 EAU82201.2 - 4.5e-16 59.2 0.3 7.5e-16 58.5 0.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU82201.2 - 1.6e-11 44.7 5.1 3.6e-09 37.2 0.3 3.1 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_61 PF03443.14 EAU82202.1 - 1.3e-43 149.4 0.0 1.6e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_6 PF01341.17 EAU82203.1 - 2.2e-99 333.0 0.4 2.8e-99 332.7 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Peptidase_S8 PF00082.22 EAU82204.2 - 1.9e-28 99.6 19.3 8.3e-28 97.5 19.3 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAU82204.2 - 4.4e-07 30.5 0.0 3.2e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 Tmem26 PF09772.9 EAU82206.1 - 0.22 10.8 0.1 0.31 10.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 26 Zip PF02535.22 EAU82206.1 - 0.28 10.4 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TT_ORF1 PF02956.14 EAU82206.1 - 4.5 5.8 9.2 5.3 5.6 9.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 stn_TNFRSF12A PF12191.8 EAU82207.1 - 0.00011 22.5 0.2 0.00039 20.6 0.0 1.9 2 0 0 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CwsA PF10814.8 EAU82207.1 - 0.016 15.4 1.3 0.03 14.5 1.3 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA TMEM154 PF15102.6 EAU82207.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF3169 PF11368.8 EAU82207.1 - 0.032 13.8 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Herpes_gE PF02480.16 EAU82207.1 - 0.066 12.0 0.0 0.092 11.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 EAU82207.1 - 0.12 13.3 0.0 0.19 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4597 PF15366.6 EAU82207.1 - 0.13 12.0 1.4 3.7 7.3 0.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4597) PGI PF00342.19 EAU82208.1 - 3.3e-233 774.6 0.4 3.9e-233 774.4 0.4 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Defensin_5 PF18251.1 EAU82209.1 - 6.2e-21 74.2 22.3 6.2e-21 74.2 22.3 2.3 3 0 0 3 3 3 1 Fungal defensin Copsin CFEM PF05730.11 EAU82209.1 - 0.00079 19.5 7.1 0.00079 19.5 7.1 2.7 2 1 0 2 2 2 1 CFEM domain CFEM PF05730.11 EAU82212.2 - 6.1e-05 23.0 3.3 0.00011 22.2 3.3 1.4 1 0 0 1 1 1 1 CFEM domain Peptidase_S8 PF00082.22 EAU82213.1 - 5.1e-31 108.1 25.4 1.8e-30 106.3 25.4 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAU82213.1 - 3.4e-08 34.0 0.1 1.9e-05 25.2 0.0 2.4 1 1 1 2 2 2 2 Peptidase inhibitor I9 TPP_enzyme_N PF02776.18 EAU82213.1 - 0.047 13.3 2.0 0.12 12.0 2.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF5039 PF16442.5 EAU82214.1 - 0.83 9.2 5.0 0.51 9.8 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) 7TM_GPCR_Sru PF10322.9 EAU82217.2 - 0.037 13.4 0.8 0.049 13.0 0.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Neil1-DNA_bind PF09292.10 EAU82218.2 - 0.082 12.9 1.5 0.39 10.7 0.1 2.6 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind BBE PF08031.12 EAU82222.2 - 4.8e-09 36.2 0.0 9.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EAU82222.2 - 7e-06 25.8 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain GST_N_2 PF13409.6 EAU82225.1 - 9.8e-10 38.6 0.0 2.1e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU82225.1 - 1e-09 38.7 0.1 5.7e-09 36.3 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU82225.1 - 0.00026 21.1 0.2 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU82225.1 - 0.0061 16.6 0.1 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain V_ATPase_I PF01496.19 EAU82228.2 - 0.0047 14.9 0.7 0.0095 13.9 0.7 1.4 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CREPT PF16566.5 EAU82228.2 - 0.19 11.9 1.4 0.43 10.7 1.4 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF3340 PF11818.8 EAU82228.2 - 1.9 8.6 6.1 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) ProQ PF04352.13 EAU82233.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 ProQ/FINO family Type_III_YscX PF09474.10 EAU82234.1 - 0.089 13.1 0.1 0.15 12.4 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Vma12 PF11712.8 EAU82235.1 - 0.68 10.0 2.4 4.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase FHA PF00498.26 EAU82236.2 - 3.7e-17 62.4 0.0 8.6e-17 61.3 0.0 1.7 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAU82236.2 - 0.00039 20.7 0.0 0.0015 18.8 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain CAP_N PF01213.19 EAU82236.2 - 0.43 10.0 7.0 0.15 11.6 4.0 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EAU82236.2 - 3.1 7.8 12.2 0.023 14.8 3.1 2.1 3 0 0 3 3 3 0 Mitochondrial fission regulator YabA PF06156.13 EAU82236.2 - 6.7 7.4 8.3 1.5 9.5 3.9 2.1 2 0 0 2 2 2 0 Initiation control protein YabA STE2 PF02116.15 EAU82237.2 - 0.26 10.6 6.9 0.43 9.9 6.9 1.3 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR PAPA-1 PF04795.12 EAU82238.2 - 1.4e-18 67.4 8.1 1.4e-18 67.4 8.1 5.5 5 3 1 6 6 6 1 PAPA-1-like conserved region DUF3602 PF12223.8 EAU82241.2 - 7.3e-23 81.0 30.3 2.3e-08 34.5 5.9 5.0 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) zf-MYND PF01753.18 EAU82242.2 - 2.1e-10 40.5 8.7 5.8e-10 39.1 8.7 1.8 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 EAU82242.2 - 0.017 16.3 0.2 0.039 15.1 0.2 1.7 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF735 PF05246.11 EAU82243.1 - 0.082 12.9 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF735) Na_K-ATPase PF00287.18 EAU82243.1 - 1.8 7.7 2.7 3.5 6.7 0.2 1.9 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain TctB PF07331.11 EAU82243.1 - 3.1 8.1 11.0 1.8 8.9 1.5 2.3 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Pheromone PF08015.11 EAU82247.1 - 0.0094 17.0 4.0 0.0094 17.0 4.0 2.1 2 1 0 2 2 2 1 Fungal mating-type pheromone NAM-associated PF14303.6 EAU82247.1 - 0.07 13.8 0.8 0.13 13.0 0.8 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SSP160 PF06933.11 EAU82247.1 - 0.095 10.9 4.5 0.13 10.4 4.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Kdo PF06293.14 EAU82253.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Complex1_LYR PF05347.15 EAU82253.1 - 1.3 9.1 4.7 4.5 7.4 4.7 1.9 1 0 0 1 1 1 0 Complex 1 protein (LYR family) HNH_2 PF13391.6 EAU82257.2 - 0.0013 18.8 0.1 0.0019 18.3 0.1 1.3 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_11 PF00457.17 EAU82258.1 - 1.1e-70 236.9 19.7 1.2e-70 236.7 19.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DEAD PF00270.29 EAU82260.2 - 1.8e-15 57.1 0.0 2.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU82260.2 - 9.3e-08 32.4 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU82260.2 - 0.12 12.4 0.0 0.52 10.3 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit F-box-like PF12937.7 EAU82261.1 - 6.7e-08 32.3 1.2 6.7e-08 32.3 1.2 2.0 2 1 0 2 2 2 1 F-box-like GNAT_acetyltr_2 PF13718.6 EAU82262.2 - 5.3e-88 294.2 0.0 1.1e-87 293.2 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EAU82262.2 - 4.2e-70 236.1 4.6 3.5e-38 131.6 0.0 2.6 2 1 0 2 2 2 2 Possible tRNA binding domain Helicase_RecD PF05127.14 EAU82262.2 - 2.2e-58 197.0 0.1 1.3e-57 194.5 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EAU82262.2 - 2.4e-33 114.0 0.8 5e-33 112.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 EAU82262.2 - 0.0013 19.0 0.0 0.02 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Acetyltransf_7 PF13508.7 EAU82262.2 - 0.023 15.1 0.0 0.1 13.0 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU82262.2 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family eIF3_N PF09440.10 EAU82264.1 - 3.9e-47 160.0 2.7 3.9e-47 160.0 2.7 2.7 2 1 1 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EAU82264.1 - 9.5e-11 42.1 0.1 3.7e-10 40.2 0.1 2.1 1 0 0 1 1 1 1 PCI domain CagZ PF09053.10 EAU82264.1 - 0.013 15.2 0.2 0.022 14.4 0.2 1.3 1 0 0 1 1 1 0 CagZ CSN8_PSD8_EIF3K PF10075.9 EAU82264.1 - 0.04 13.9 0.4 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family TipAS PF07739.13 EAU82264.1 - 0.049 14.2 1.4 0.076 13.6 0.1 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain zf-C2H2 PF00096.26 EAU82265.2 - 1.2e-09 38.1 9.7 0.00028 21.2 2.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU82265.2 - 2.5e-06 27.9 7.0 0.02 15.7 1.7 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU82265.2 - 0.00028 21.2 8.9 0.0053 17.1 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EAU82265.2 - 0.35 11.2 1.4 2.3 8.6 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EAU82265.2 - 4.4 7.3 8.7 4.6 7.3 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Hydrolase_6 PF13344.6 EAU82267.1 - 2.4e-13 50.1 0.0 4.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU82267.1 - 1.3e-10 41.2 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like PLAC8 PF04749.17 EAU82268.2 - 1.6e-22 80.3 7.2 2e-22 80.0 7.2 1.1 1 0 0 1 1 1 1 PLAC8 family Extensin_2 PF04554.13 EAU82268.2 - 0.55 10.3 33.6 0.37 10.9 25.8 2.9 2 1 0 2 2 2 0 Extensin-like region DnaJ PF00226.31 EAU82269.1 - 7.6e-18 64.4 0.3 7.6e-18 64.4 0.3 2.3 4 0 0 4 4 2 1 DnaJ domain TPR_19 PF14559.6 EAU82269.1 - 2.1e-15 57.0 3.6 8.3e-05 23.0 0.1 5.9 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAU82269.1 - 5.6e-15 54.4 1.3 0.00038 20.2 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAU82269.1 - 2.2e-13 49.2 12.0 0.00085 19.3 0.0 6.8 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU82269.1 - 5.2e-11 41.9 6.8 0.032 14.4 0.1 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU82269.1 - 5.9e-11 42.8 10.7 5.8e-06 26.9 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAU82269.1 - 2.5e-10 40.3 6.7 0.017 15.9 0.0 5.8 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EAU82269.1 - 2.3e-09 37.0 1.3 0.0037 17.5 0.1 5.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU82269.1 - 6.5e-09 36.0 4.0 0.017 15.4 0.5 4.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 EAU82269.1 - 1.7e-07 31.1 0.1 0.2 12.4 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU82269.1 - 5.5e-06 26.0 0.8 7.7e-05 22.3 0.3 3.2 2 1 1 3 3 3 1 TPR repeat TPR_9 PF13371.6 EAU82269.1 - 7e-06 26.1 3.7 0.1 12.8 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU82269.1 - 7.3e-06 25.6 2.9 0.21 11.7 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAU82269.1 - 2.2e-05 24.8 6.7 6 7.7 0.2 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAU82269.1 - 0.00017 21.3 5.5 1.2 9.1 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF3808 PF10300.9 EAU82269.1 - 0.0015 17.4 0.1 0.0042 15.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 EAU82269.1 - 0.0047 17.1 7.6 0.031 14.5 0.6 4.1 3 3 3 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 EAU82269.1 - 0.02 13.6 0.7 0.29 9.8 0.0 2.8 2 1 1 3 3 3 0 Protein kinase G tetratricopeptide repeat Thioredoxin_8 PF13905.6 EAU82269.1 - 0.039 14.3 0.1 0.18 12.2 0.0 2.1 2 0 0 2 2 1 0 Thioredoxin-like MIT PF04212.18 EAU82269.1 - 0.04 14.0 1.1 2.3 8.4 0.0 3.7 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain TMF_TATA_bd PF12325.8 EAU82269.1 - 0.083 13.1 1.1 0.51 10.6 0.1 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_20 PF14561.6 EAU82269.1 - 0.92 9.9 6.0 1.1 9.6 0.1 3.7 3 2 2 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 EAU82269.1 - 1.4 9.4 5.7 13 6.2 0.0 3.7 2 1 1 3 3 3 0 Bacterial transcriptional activator domain AcetylCoA_hyd_C PF13336.6 EAU82276.1 - 1.6e-41 141.8 0.0 2.4e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 EAU82276.1 - 3e-41 141.6 0.0 4.7e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain Tom37 PF10568.9 EAU82276.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein DUF4029 PF13221.6 EAU82277.2 - 0.063 13.9 0.3 0.063 13.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Srg PF02118.21 EAU82277.2 - 0.069 12.8 7.6 0.064 12.9 4.3 1.9 2 0 0 2 2 2 0 Srg family chemoreceptor TraP PF07296.11 EAU82277.2 - 0.26 10.4 1.6 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 TraP protein Wzz PF02706.15 EAU82278.2 - 0.12 12.6 0.2 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 Chain length determinant protein Syndecan PF01034.20 EAU82279.1 - 0.00062 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 EAU82279.1 - 0.079 13.9 0.0 0.13 13.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 EAU82279.1 - 0.097 12.7 1.1 0.14 12.1 0.2 1.6 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2062 PF09835.9 EAU82279.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) stn_TNFRSF12A PF12191.8 EAU82279.1 - 0.3 11.3 0.8 1.7 8.8 0.2 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zf-MYND PF01753.18 EAU82280.2 - 1.6e-09 37.7 11.2 2.7e-09 37.0 11.2 1.4 1 0 0 1 1 1 1 MYND finger DUF3514 PF12027.8 EAU82280.2 - 0.08 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) zf-Mss51 PF13824.6 EAU82280.2 - 0.1 12.7 5.3 0.2 11.8 5.3 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EAU82282.1 - 5.1e-11 42.5 8.5 7.8e-11 41.9 8.5 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EAU82282.1 - 0.0075 16.3 5.6 0.014 15.5 5.6 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EAU82284.2 - 1.1e-06 28.7 12.1 1.1e-06 28.7 12.1 2.3 2 0 0 2 2 2 1 MYND finger Viral_helicase1 PF01443.18 EAU82284.2 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DEC-1_N PF04625.13 EAU82285.1 - 0.39 9.7 2.6 0.71 8.8 2.6 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 EAU82285.1 - 3.4 7.1 4.4 4.8 6.6 4.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal F-box-like PF12937.7 EAU82286.2 - 0.011 15.6 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 EAU82287.2 - 5.6e-32 111.0 28.4 5.6e-32 111.0 28.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DEC-1_N PF04625.13 EAU82289.1 - 0.0054 15.8 10.8 0.0051 15.9 10.8 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region ATP19 PF11022.8 EAU82292.1 - 0.036 14.4 0.1 7.8 7.0 0.1 2.3 2 0 0 2 2 2 0 ATP synthase subunit K DUF1996 PF09362.10 EAU82295.2 - 8.9e-71 238.6 0.0 1.1e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF5553 PF17707.1 EAU82296.2 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5553) GRDP-like PF07173.12 EAU82297.1 - 0.057 14.1 0.1 0.068 13.8 0.1 1.1 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like EphA2_TM PF14575.6 EAU82300.2 - 0.064 14.1 0.0 0.35 11.8 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LST1 PF05083.13 EAU82300.2 - 0.08 13.2 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein FeoB_associated PF12669.7 EAU82300.2 - 0.095 13.1 0.2 0.15 12.5 0.2 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3923 PF13061.6 EAU82301.1 - 3.6 7.7 7.4 0.35 11.0 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) DUF5624 PF18538.1 EAU82304.2 - 0.18 11.9 0.4 0.36 10.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) DUF4470 PF14737.6 EAU82305.1 - 2.2e-20 72.6 0.0 4.3e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EAU82305.1 - 1.5e-10 40.9 16.5 3.4e-10 39.9 16.5 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EAU82305.1 - 2.2 8.2 10.0 6.9 6.6 10.0 1.9 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 EAU82305.1 - 4 7.8 11.8 12 6.3 11.8 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Plavaka PF18759.1 EAU82306.2 - 8.4e-124 413.0 0.0 1.2e-123 412.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase DNA_pol_phi PF04931.13 EAU82306.2 - 0.042 12.0 5.0 0.078 11.1 5.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EAU82306.2 - 0.14 11.4 8.7 0.27 10.5 8.7 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3245 PF11595.8 EAU82306.2 - 0.27 11.7 2.0 1.9 8.9 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) CDC45 PF02724.14 EAU82306.2 - 0.35 9.1 0.7 0.5 8.6 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EAU82306.2 - 0.88 9.2 5.2 1.5 8.5 5.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EAU82306.2 - 4.5 5.4 6.7 7.1 4.7 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family Rax2 PF12768.7 EAU82308.1 - 0.0079 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity SKG6 PF08693.10 EAU82308.1 - 0.012 15.0 2.4 0.024 14.1 2.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EAU82308.1 - 0.029 15.2 0.0 0.047 14.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 EAU82308.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF1996 PF09362.10 EAU82309.1 - 2.3e-83 279.8 0.3 2.7e-83 279.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NPR3 PF03666.13 EAU82312.1 - 0.003 16.4 2.4 0.0039 16.1 2.4 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.7 EAU82312.1 - 0.51 8.4 1.1 0.59 8.2 1.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DPM3 PF08285.11 EAU82315.2 - 1.1 9.5 3.5 0.34 11.1 0.4 1.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RRM_1 PF00076.22 EAU82321.1 - 1.4e-31 108.2 0.1 2e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU82321.1 - 1.5e-11 44.3 0.1 5.4e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EAU82321.1 - 0.015 15.3 0.0 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HNF-1_N PF04814.13 EAU82321.1 - 0.9 10.1 8.4 1.4 9.5 8.4 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Mucin PF01456.17 EAU82321.1 - 2.2 8.3 25.7 3.6 7.6 25.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PRCC PF10253.9 EAU82321.1 - 2.7 8.7 12.9 4.5 8.0 12.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SNO PF01174.19 EAU82322.1 - 5e-48 163.5 0.0 5.2e-47 160.1 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EAU82322.1 - 7.7e-11 41.9 0.0 9.8e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EAU82322.1 - 7.5e-06 25.7 0.1 1.6e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EAU82322.1 - 0.00077 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EAU82322.1 - 0.034 13.9 0.2 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Aldolase PF01081.19 EAU82322.1 - 0.067 12.6 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 KDPG and KHG aldolase NARP1 PF12569.8 EAU82326.2 - 0.3 10.0 1.8 0.49 9.2 1.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4436 PF14494.6 EAU82328.2 - 2.8e-08 33.4 2.4 3.8e-08 32.9 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Proton_antipo_N PF00662.20 EAU82328.2 - 0.1 12.7 2.7 0.14 12.3 0.1 2.4 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Sigma_M_inh PF17453.2 EAU82328.2 - 0.25 11.8 5.0 0.47 10.9 5.0 1.4 1 0 0 1 1 1 0 Sigma-M inhibitor p450 PF00067.22 EAU82330.1 - 2.4e-57 194.7 0.0 3.4e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_1 PF00561.20 EAU82331.1 - 2.8e-18 66.5 0.0 2.5e-16 60.1 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU82331.1 - 1.2e-17 65.2 0.1 1.6e-17 64.9 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU82331.1 - 1.3e-10 41.0 0.0 3.6e-07 29.7 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EAU82331.1 - 6.9e-08 32.4 0.0 0.0084 15.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ndr PF03096.14 EAU82331.1 - 2.2e-05 23.3 0.0 2.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family FSH1 PF03959.13 EAU82331.1 - 0.0052 16.5 0.0 0.062 13.0 0.0 2.4 3 0 0 3 3 3 1 Serine hydrolase (FSH1) DLH PF01738.18 EAU82331.1 - 0.027 14.0 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Sec63 PF02889.16 EAU82333.1 - 5.7e-16 58.5 0.0 8.7e-15 54.6 0.0 2.2 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 EAU82333.1 - 1.1e-15 57.4 0.3 2.5e-15 56.3 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4605 PF15378.6 EAU82333.1 - 0.098 12.5 0.6 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Myb_DNA-bind_4 PF13837.6 EAU82333.1 - 0.16 12.3 0.7 0.52 10.7 0.7 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Methyltransf_2 PF00891.18 EAU82335.1 - 1.6e-25 89.7 0.0 6.6e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 EAU82335.1 - 5.6e-05 23.0 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU82335.1 - 0.00028 21.5 0.0 0.00059 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU82335.1 - 0.0054 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EAU82335.1 - 0.017 15.0 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAU82335.1 - 0.032 15.0 0.0 0.079 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation2 PF16864.5 EAU82335.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Cpn60_TCP1 PF00118.24 EAU82336.1 - 6.8e-147 490.0 14.4 7.7e-147 489.9 14.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EAU82336.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat PMT PF02366.18 EAU82337.2 - 4.7e-83 278.5 11.1 4.7e-83 278.5 11.1 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAU82337.2 - 5.2e-66 222.1 16.7 5.2e-66 222.1 16.7 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EAU82337.2 - 5.9e-40 137.1 0.2 1.3e-39 136.0 0.2 1.6 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EAU82337.2 - 3.2e-06 27.4 7.0 3.2e-06 27.4 7.0 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.12 EAU82337.2 - 0.92 10.1 4.5 34 5.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) HRG PF16954.5 EAU82338.2 - 0.02 15.3 0.6 0.061 13.7 0.6 1.8 1 0 0 1 1 1 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene p450 PF00067.22 EAU82339.2 - 2.1e-66 224.6 0.0 3.2e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyc_hyd_38C_2 PF18230.1 EAU82342.2 - 0.16 12.1 0.1 0.95 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal sub-domain F_bP_aldolase PF01116.20 EAU82343.1 - 2.8e-92 309.2 0.0 3.1e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Cyclin_C_2 PF16899.5 EAU82345.2 - 0.017 15.5 0.1 0.045 14.2 0.1 1.6 1 0 0 1 1 1 0 Cyclin C-terminal domain Ldh_1_C PF02866.18 EAU82346.1 - 2.6e-46 157.6 0.0 5.1e-46 156.6 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EAU82346.1 - 2.4e-44 150.9 0.0 3.4e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EAU82346.1 - 0.00047 19.3 0.0 0.00068 18.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EAU82346.1 - 0.058 12.9 0.1 3.9 7.0 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 EAU82346.1 - 0.067 13.6 0.1 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EAU82346.1 - 0.095 12.8 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Abhydrolase_1 PF00561.20 EAU82347.2 - 1.3e-24 87.2 0.0 2.9e-24 86.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EAU82347.2 - 2.2e-24 85.5 0.0 5e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein GPI2 PF06432.11 EAU82347.2 - 0.22 10.9 0.3 0.36 10.2 0.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase UPRTase PF14681.6 EAU82349.2 - 6.1e-60 202.2 0.0 2.7e-59 200.1 0.0 1.8 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Abhydrolase_1 PF00561.20 EAU82350.1 - 1.2e-29 103.7 0.0 9.2e-29 100.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EAU82350.1 - 1e-22 80.2 0.0 2.2e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EAU82351.2 - 3.1e-23 82.7 0.1 4.7e-23 82.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EAU82351.2 - 7.8e-15 54.9 0.0 6.2e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 TAP-like protein Glyco_hydro_30 PF02055.16 EAU82351.2 - 0.18 10.8 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain Tcf25 PF04910.14 EAU82353.2 - 2.2e-78 263.8 0.0 1.1e-77 261.5 0.0 2.1 2 1 1 3 3 3 1 Transcriptional repressor TCF25 Ndc1_Nup PF09531.10 EAU82353.2 - 3.5 6.2 10.5 5.5 5.6 10.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_phi PF04931.13 EAU82353.2 - 6 4.8 22.9 0.99 7.4 14.1 2.2 2 0 0 2 2 2 0 DNA polymerase phi TIP49 PF06068.13 EAU82356.1 - 1.9e-160 533.9 0.1 2.2e-160 533.6 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EAU82356.1 - 1.6e-19 69.8 0.0 3.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EAU82356.1 - 1.3e-10 41.8 0.0 1.5e-06 28.7 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAU82356.1 - 4.1e-09 36.4 0.0 2e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAU82356.1 - 4.5e-06 27.0 0.1 0.054 13.8 0.2 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EAU82356.1 - 1.1e-05 25.9 0.0 7.4e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAU82356.1 - 1.5e-05 25.0 0.1 0.008 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EAU82356.1 - 0.00089 19.5 0.1 0.0019 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU82356.1 - 0.00094 19.5 0.5 0.0054 17.1 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAU82356.1 - 0.005 16.4 0.6 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EAU82356.1 - 0.014 15.9 0.0 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAU82356.1 - 0.017 15.3 0.0 0.07 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EAU82356.1 - 0.018 14.4 0.1 0.09 12.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAU82356.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EAU82356.1 - 0.023 14.4 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 EAU82356.1 - 0.033 14.2 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 EAU82356.1 - 0.035 13.4 0.3 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 EAU82356.1 - 0.048 13.1 0.3 1.9 7.9 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein AAA_7 PF12775.7 EAU82356.1 - 0.049 13.1 0.1 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EAU82356.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_lid_2 PF17863.1 EAU82356.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA lid domain AAA_14 PF13173.6 EAU82356.1 - 0.14 12.2 0.0 17 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EAU82356.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PNP_UDP_1 PF01048.20 EAU82357.1 - 1.1e-31 109.9 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.18 EAU82358.2 - 5.2e-33 114.2 0.0 7.9e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU82358.2 - 4.5e-07 29.9 9.2 7.8e-07 29.1 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.6 EAU82363.2 - 3.6e-08 34.0 0.0 7.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EAU82363.2 - 1e-05 25.5 0.0 3.3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 EAU82363.2 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EAU82363.2 - 0.002 18.4 0.0 0.0066 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EAU82363.2 - 0.0032 17.8 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EAU82363.2 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EAU82363.2 - 0.033 13.4 0.3 0.11 11.8 0.1 1.8 1 1 1 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 EAU82363.2 - 0.1 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 EAU82364.1 - 2.6e-12 46.7 0.0 7.3e-10 38.7 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU82364.1 - 0.0021 17.4 0.0 0.005 16.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU82364.1 - 0.0024 16.7 0.0 0.0028 16.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EAU82364.1 - 0.051 13.2 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA_16 PF13191.6 EAU82365.2 - 2.7e-05 24.6 0.0 4.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EAU82365.2 - 0.0047 17.0 0.0 2 8.4 0.0 2.6 2 1 0 3 3 3 2 AAA domain Tnp_DNA_bind PF14706.6 EAU82365.2 - 0.055 13.3 0.4 0.15 11.9 0.4 1.7 1 0 0 1 1 1 0 Transposase DNA-binding NACHT PF05729.12 EAU82365.2 - 0.08 12.8 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Topoisom_I_N PF02919.15 EAU82365.2 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Pkinase PF00069.25 EAU82366.1 - 7.5e-14 51.7 0.1 7.4e-12 45.2 0.1 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU82366.1 - 4e-06 26.3 0.1 1.5e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU82366.1 - 0.005 15.7 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4962 PF16332.5 EAU82368.1 - 0.0079 14.8 1.7 0.018 13.6 1.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4962) Abhydrolase_6 PF12697.7 EAU82371.1 - 1.8e-16 61.5 1.0 2.1e-16 61.2 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU82371.1 - 0.056 12.7 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LysM PF01476.20 EAU82372.2 - 4.5e-15 55.4 0.1 5e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 LysM domain F-box-like PF12937.7 EAU82373.2 - 0.003 17.4 0.2 0.0071 16.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU82373.2 - 0.015 15.2 0.3 0.044 13.7 0.2 1.8 2 0 0 2 2 2 0 F-box domain LysM PF01476.20 EAU82374.2 - 4.7e-19 68.2 0.0 1.5e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 LysM domain Npa1 PF11707.8 EAU82375.1 - 1.3e-72 245.1 0.0 3.4e-72 243.7 0.0 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EAU82375.1 - 1.7e-54 184.5 0.5 7.3e-54 182.4 0.3 2.3 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 EAU82375.1 - 0.0002 22.0 0.3 0.0024 18.6 0.0 2.8 3 0 0 3 3 3 1 Creb binding CDC45 PF02724.14 EAU82375.1 - 0.056 11.7 2.0 0.09 11.1 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein UTP15_C PF09384.10 EAU82375.1 - 0.11 12.1 0.8 5.1 6.8 0.3 3.1 3 0 0 3 3 3 0 UTP15 C terminal RPN2_C PF18004.1 EAU82375.1 - 0.39 10.6 1.7 0.85 9.5 1.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 EAU82375.1 - 0.64 8.2 8.6 2.1 6.5 8.6 1.8 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EAU82375.1 - 8.2 5.7 12.2 0.16 11.3 5.3 1.5 2 0 0 2 2 2 0 SDA1 Fungal_trans PF04082.18 EAU82376.2 - 1.9e-27 96.0 0.1 3.4e-27 95.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU82376.2 - 0.0017 18.4 6.1 0.0033 17.5 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRBF2 PF08961.10 EAU82377.2 - 0.0053 16.4 0.4 0.0053 16.4 0.4 2.1 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator DUF4055 PF13264.6 EAU82377.2 - 0.094 12.9 3.7 0.15 12.2 1.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) YabA PF06156.13 EAU82377.2 - 0.29 11.8 1.5 0.96 10.1 1.5 1.9 1 0 0 1 1 1 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 EAU82377.2 - 1.4 9.2 9.0 0.054 13.7 2.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 EAU82377.2 - 5.4 7.1 12.6 0.064 13.3 4.3 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NUDIX PF00293.28 EAU82378.2 - 3e-10 40.2 0.0 3.1e-08 33.7 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain NUDIX_4 PF14815.6 EAU82378.2 - 0.069 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain OTT_1508_deam PF14441.6 EAU82381.1 - 2e-07 30.9 0.1 4.1e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase F-box-like PF12937.7 EAU82383.1 - 0.0012 18.6 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU82383.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.7 2 0 0 2 2 2 0 F-box domain WGG PF10273.9 EAU82384.1 - 9.6e-29 99.9 0.3 2.2e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 NOA36 PF06524.12 EAU82384.1 - 8.5 5.6 7.2 11 5.2 7.2 1.1 1 0 0 1 1 1 0 NOA36 protein CBFD_NFYB_HMF PF00808.23 EAU82385.2 - 2.6e-14 53.3 0.9 2.2e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU82385.2 - 3.6e-07 30.6 0.4 1.8e-06 28.3 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CAF1-p150_N PF15557.6 EAU82385.2 - 0.054 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA CCB2_CCB4 PF11152.8 EAU82385.2 - 0.07 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 F-box-like PF12937.7 EAU82387.2 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like RNA_pol_L PF01193.24 EAU82387.2 - 0.029 13.8 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain F-box PF00646.33 EAU82387.2 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain RTA1 PF04479.13 EAU82388.1 - 6.6e-65 218.6 3.1 1.1e-64 217.9 3.1 1.3 1 0 0 1 1 1 1 RTA1 like protein CitMHS PF03600.16 EAU82388.1 - 0.0064 15.7 2.6 0.0088 15.3 2.6 1.2 1 0 0 1 1 1 1 Citrate transporter PsbH PF00737.20 EAU82388.1 - 0.039 13.7 0.7 0.27 11.0 0.0 2.7 3 0 0 3 3 3 0 Photosystem II 10 kDa phosphoprotein Glyco_hydro_92 PF07971.12 EAU82390.2 - 8.8e-126 420.5 0.7 1.1e-125 420.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EAU82390.2 - 3.7e-36 125.2 0.6 6.7e-36 124.4 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain F-box-like PF12937.7 EAU82391.1 - 0.08 12.8 2.1 0.18 11.7 0.1 2.6 3 0 0 3 3 3 0 F-box-like RRM_5 PF13893.6 EAU82391.1 - 0.084 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5402 PF17393.2 EAU82394.2 - 0.054 13.4 0.0 0.092 12.7 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5402) F-box-like PF12937.7 EAU82397.2 - 0.0093 15.8 1.2 0.022 14.7 0.0 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EAU82397.2 - 0.029 14.3 1.7 0.06 13.2 0.1 2.4 2 0 0 2 2 2 0 F-box domain DUF3557 PF12078.8 EAU82397.2 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) RTA1 PF04479.13 EAU82398.1 - 7.5e-62 208.6 3.2 7.5e-62 208.6 3.2 1.4 1 1 1 2 2 2 1 RTA1 like protein F-box-like PF12937.7 EAU82399.2 - 0.00099 19.0 0.1 0.007 16.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like Peroxidase_2 PF01328.17 EAU82400.2 - 7.6e-32 111.4 0.0 9.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Ald_Xan_dh_C2 PF02738.18 EAU82400.2 - 0.093 11.2 0.4 0.18 10.2 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin-binding domain of aldehyde dehydrogenase MIT PF04212.18 EAU82401.2 - 0.00057 19.9 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FANCA_interact PF15751.5 EAU82401.2 - 0.0017 18.8 0.9 0.057 13.9 0.1 2.5 2 0 0 2 2 2 1 FAAP20 FANCA interaction domain Suf PF05843.14 EAU82402.2 - 1.3e-76 258.4 5.1 1.5e-74 251.6 0.0 4.1 3 2 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EAU82402.2 - 6.8e-09 35.8 5.0 0.28 12.1 0.0 7.7 5 3 4 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAU82402.2 - 1.8e-05 25.2 0.2 1.9 9.1 0.0 4.5 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EAU82402.2 - 0.00017 20.9 5.8 0.84 8.8 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat FTCD_C PF04961.12 EAU82402.2 - 0.0066 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase TPR_6 PF13174.6 EAU82402.2 - 0.054 14.1 1.2 16 6.4 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat RP-C_C PF11800.8 EAU82402.2 - 4.8 7.2 5.1 4.8 7.2 2.6 2.2 2 1 0 2 2 2 0 Replication protein C C-terminal region TPR_2 PF07719.17 EAU82402.2 - 6.5 7.1 5.3 1.2e+02 3.2 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Rsa3 PF14615.6 EAU82404.1 - 1.1e-15 56.9 0.1 1.5e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 IMUP PF15761.5 EAU82404.1 - 0.053 14.2 11.2 0.053 14.2 11.2 2.6 1 1 1 2 2 2 0 Immortalisation up-regulated protein Macoilin PF09726.9 EAU82404.1 - 0.15 10.6 12.2 0.18 10.4 12.2 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EAU82404.1 - 0.38 9.6 18.1 0.46 9.3 18.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EAU82404.1 - 0.89 8.7 24.4 1.1 8.4 24.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PNISR PF15996.5 EAU82404.1 - 0.94 9.7 11.0 1.2 9.3 11.0 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR LAP1C PF05609.12 EAU82404.1 - 1.1 8.3 12.4 1.4 8.0 12.4 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 EAU82404.1 - 1.3 7.7 10.7 1.6 7.4 10.7 1.2 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 EAU82404.1 - 1.8 7.1 24.5 2.1 6.8 24.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sec10 PF07393.11 EAU82404.1 - 2.1 6.6 7.4 2.7 6.3 7.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 XAP5 PF04921.14 EAU82404.1 - 2.3 8.0 12.0 0.27 11.0 2.4 2.0 1 1 1 2 2 2 0 XAP5, circadian clock regulator Zip PF02535.22 EAU82404.1 - 2.4 7.3 5.0 3 7.0 5.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Sporozoite_P67 PF05642.11 EAU82404.1 - 3.2 5.7 19.9 4.2 5.3 19.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Totivirus_coat PF05518.11 EAU82404.1 - 3.7 5.5 8.0 4.4 5.2 8.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF4551 PF15087.6 EAU82404.1 - 4.7 5.9 14.3 4.8 5.9 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM60A PF15396.6 EAU82404.1 - 5.7 6.9 12.1 8.7 6.3 12.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S64 PF08192.11 EAU82404.1 - 7.2 5.0 11.5 7.3 4.9 11.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 NST1 PF13945.6 EAU82404.1 - 9.1 6.3 18.3 2.1 8.4 1.0 2.2 1 1 1 2 2 2 0 Salt tolerance down-regulator SPX PF03105.19 EAU82404.1 - 9.5 6.0 26.0 11 5.8 26.0 1.1 1 0 0 1 1 1 0 SPX domain AIRC PF00731.20 EAU82405.2 - 1.3e-63 213.0 2.1 2.7e-63 212.0 2.1 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EAU82405.2 - 1.4e-57 194.0 0.0 2.1e-57 193.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EAU82405.2 - 6.7e-21 73.7 0.0 1.4e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EAU82405.2 - 0.0032 17.0 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.11 EAU82405.2 - 0.026 14.1 0.5 0.22 11.1 0.1 2.3 2 0 0 2 2 2 0 Propionate catabolism activator ATP-grasp_3 PF02655.14 EAU82405.2 - 0.099 12.7 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain CoA_binding_2 PF13380.6 EAU82405.2 - 0.13 12.8 2.7 17 5.9 0.1 4.0 3 2 1 4 4 4 0 CoA binding domain TPR_1 PF00515.28 EAU82406.2 - 7.3e-06 25.6 0.4 0.00015 21.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU82406.2 - 0.0014 18.5 0.3 0.0068 16.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU82406.2 - 0.0099 15.5 0.4 0.02 14.6 0.4 1.5 1 0 0 1 1 1 1 TPR repeat TPR_3 PF07720.12 EAU82406.2 - 0.034 14.1 0.7 0.057 13.4 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU82406.2 - 0.098 12.9 0.3 0.59 10.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU82406.2 - 0.1 12.9 0.0 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU82407.2 - 3.5e-13 48.8 3.1 6.3e-05 22.6 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU82407.2 - 1.6e-12 46.5 3.6 0.00056 19.8 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU82407.2 - 5.8e-06 26.1 1.1 0.05 13.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU82407.2 - 1.4e-05 25.2 2.0 0.00054 20.2 1.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU82407.2 - 0.009 15.7 0.4 0.028 14.1 0.3 1.9 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EAU82407.2 - 0.037 14.7 0.1 0.21 12.3 0.0 2.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU82407.2 - 0.039 14.0 1.1 35 4.7 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAU82407.2 - 0.063 13.9 0.1 21 6.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU82407.2 - 0.13 12.2 1.2 1.3 9.0 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec8_exocyst PF04048.14 EAU82407.2 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TPR_1 PF00515.28 EAU82408.2 - 2e-10 40.0 0.2 0.00037 20.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU82408.2 - 5.5e-09 35.5 0.5 0.035 14.2 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAU82408.2 - 3e-07 30.6 1.5 0.37 11.5 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU82408.2 - 7.5e-06 25.8 0.3 0.067 13.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU82408.2 - 0.00023 21.4 0.2 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU82408.2 - 0.014 16.1 0.8 20 6.3 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAU82408.2 - 0.05 14.1 0.2 6.8 7.3 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU82408.2 - 0.057 13.7 0.4 9.5 6.5 0.1 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EAU82408.2 - 0.1 12.7 0.6 9.8 6.5 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 EAU82409.1 - 1.3e-47 161.5 0.0 3.1e-41 140.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU82409.1 - 3e-10 39.8 0.0 9.6e-10 38.1 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EAU82409.1 - 1.4e-06 28.8 0.4 4.8e-05 23.8 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EAU82409.1 - 8e-06 25.7 0.0 5.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EAU82409.1 - 2.2e-05 24.6 0.0 8.3e-05 22.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 EAU82409.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.14 EAU82409.1 - 0.004 17.2 0.0 0.019 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EAU82409.1 - 0.0041 17.4 2.1 0.15 12.3 0.2 3.9 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EAU82409.1 - 0.005 16.4 0.0 0.55 9.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EAU82409.1 - 0.011 16.3 0.6 0.054 14.0 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EAU82409.1 - 0.024 14.8 1.8 0.047 13.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAU82409.1 - 0.026 15.1 0.2 0.45 11.0 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 EAU82409.1 - 0.058 12.8 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAU82409.1 - 0.064 13.5 1.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EAU82409.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 EAU82409.1 - 0.12 11.8 0.0 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 EAU82409.1 - 0.12 12.0 0.0 1.6 8.4 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain TIP49 PF06068.13 EAU82409.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EAU82409.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EAU82409.1 - 0.94 9.2 0.0 0.94 9.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain Exo_endo_phos PF03372.23 EAU82410.2 - 2.9e-10 40.1 0.1 6.3e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nodulin-like PF06813.13 EAU82411.2 - 1.3e-12 47.8 1.9 4.8e-12 45.9 1.9 2.0 1 1 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 EAU82411.2 - 2.2e-12 46.6 28.6 4.7e-12 45.5 21.2 3.5 2 1 1 3 3 3 1 Major Facilitator Superfamily CcmD PF04995.14 EAU82411.2 - 0.004 17.2 0.6 0.016 15.3 0.6 2.0 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Pec_lyase_C PF00544.19 EAU82412.2 - 1.3e-34 119.7 7.9 1.7e-34 119.3 7.9 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EAU82412.2 - 3.2e-07 30.3 11.9 0.0007 19.5 6.2 2.3 2 0 0 2 2 2 2 Right handed beta helix region RA PF00788.23 EAU82413.1 - 1.5e-11 44.8 1.8 4.7e-09 36.8 0.0 4.1 3 1 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 EAU82413.1 - 3e-06 26.8 0.1 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EAU82413.1 - 0.0011 18.8 0.2 0.0048 16.7 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Par3_HAL_N_term PF12053.8 EAU82413.1 - 0.1 12.8 0.0 0.55 10.5 0.0 2.3 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins Ank_2 PF12796.7 EAU82414.1 - 5.3e-41 139.1 4.4 9.8e-11 42.1 0.2 8.7 6 1 2 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU82414.1 - 1.8e-32 111.3 6.1 4e-07 30.4 0.1 9.0 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU82414.1 - 3.1e-29 97.7 3.7 0.02 15.4 0.0 11.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 EAU82414.1 - 5e-25 87.2 8.0 0.0054 17.0 0.0 10.4 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 EAU82414.1 - 9.9e-21 73.2 7.3 0.025 15.0 0.0 10.6 11 0 0 11 11 11 5 Ankyrin repeat DNA_binding_1 PF01035.20 EAU82415.2 - 3.8e-27 94.2 0.0 5.2e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Glyco_hydro_85 PF03644.13 EAU82416.1 - 1.2e-82 277.8 0.2 1.8e-82 277.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SDA1 PF05285.12 EAU82417.2 - 0.00038 20.0 12.6 0.00043 19.8 12.6 1.2 1 0 0 1 1 1 1 SDA1 TFIIF_alpha PF05793.12 EAU82417.2 - 0.026 13.2 12.8 0.032 12.8 12.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.12 EAU82417.2 - 0.37 9.2 13.6 0.53 8.7 13.6 1.2 1 0 0 1 1 1 0 Mpp10 protein AF-4 PF05110.13 EAU82417.2 - 0.55 8.3 12.4 0.67 8.0 12.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Herpes_LMP1 PF05297.11 EAU82417.2 - 1.3 8.1 9.1 1.6 7.8 9.1 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Presenilin PF01080.17 EAU82417.2 - 1.5 7.5 3.3 2.3 6.9 3.3 1.3 1 0 0 1 1 1 0 Presenilin SURF2 PF05477.11 EAU82417.2 - 1.6 8.4 7.3 2.2 7.9 7.3 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 EAU82417.2 - 2.6 6.2 15.3 0.22 9.7 11.0 1.4 2 0 0 2 2 2 0 CDC45-like protein eIF-3c_N PF05470.12 EAU82417.2 - 2.7 6.2 6.8 1.5 7.0 4.9 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2457 PF10446.9 EAU82417.2 - 2.8 7.0 19.0 4.2 6.4 19.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Apt1 PF10351.9 EAU82417.2 - 3.9 6.2 9.7 1.3 7.8 5.9 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain SAPS PF04499.15 EAU82417.2 - 4.9 5.8 5.7 6 5.5 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UbiA PF01040.18 EAU82418.2 - 7.3e-48 163.1 20.3 1e-47 162.6 20.3 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Coilin_N PF15862.5 EAU82421.2 - 0.00012 21.9 1.7 0.00012 21.9 1.7 4.5 4 1 0 4 4 4 1 Coilin N-terminus Mem_trans PF03547.18 EAU82421.2 - 0.026 12.9 0.0 0.28 9.5 0.0 2.0 1 1 0 1 1 1 0 Membrane transport protein DUF4614 PF15391.6 EAU82421.2 - 5.4 7.0 60.7 2.5 8.1 29.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) PPR_2 PF13041.6 EAU82422.1 - 3.1e-49 164.9 1.4 1e-08 35.2 0.0 13.5 10 3 4 14 14 14 10 PPR repeat family PPR PF01535.20 EAU82422.1 - 5.3e-44 145.4 14.6 9.6e-05 22.4 0.0 15.9 17 0 0 17 17 17 9 PPR repeat PPR_3 PF13812.6 EAU82422.1 - 5.8e-38 128.8 0.1 3.1e-09 36.8 0.0 10.6 9 2 2 11 11 11 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 EAU82422.1 - 3.3e-30 103.5 0.0 6.3e-05 22.6 0.0 11.3 11 0 0 11 11 11 8 PPR repeat PPR_long PF17177.4 EAU82422.1 - 2.1e-19 69.7 3.1 3.3e-13 49.5 0.0 5.6 5 1 0 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EAU82422.1 - 1.9e-09 37.5 7.8 0.091 13.6 0.0 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU82422.1 - 0.00049 19.9 0.2 31 4.9 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat MRP-S27 PF10037.9 EAU82422.1 - 0.071 12.0 0.0 0.27 10.0 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 TPR_16 PF13432.6 EAU82422.1 - 0.2 12.3 5.0 33 5.2 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat F-box-like PF12937.7 EAU82423.2 - 8.1e-07 28.8 0.3 2.6e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 EAU82423.2 - 0.46 11.2 0.1 0.46 11.2 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.7 EAU82424.1 - 1.2e-08 34.7 0.3 1.4e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 EAU82424.1 - 0.52 11.1 2.8 0.99 10.2 0.5 2.7 3 0 0 3 3 3 0 Leucine Rich Repeat UbiA PF01040.18 EAU82425.2 - 4.2e-27 95.0 15.2 5.6e-22 78.2 8.1 2.2 1 1 1 2 2 2 2 UbiA prenyltransferase family DUF1033 PF06279.11 EAU82426.2 - 0.04 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) RFC1 PF08519.12 EAU82427.1 - 7.8e-56 188.6 0.2 2e-54 184.0 0.0 2.8 4 0 0 4 4 3 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EAU82427.1 - 3.5e-13 49.7 0.0 1.2e-12 48.0 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EAU82427.1 - 1.5e-09 38.3 0.0 3.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAU82427.1 - 4.5e-05 23.4 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EAU82427.1 - 0.0034 17.1 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EAU82427.1 - 0.022 15.1 0.0 0.078 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain DNA_pol3_delta PF06144.13 EAU82427.1 - 0.029 14.2 0.0 0.082 12.7 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 EAU82427.1 - 0.033 14.2 0.0 0.095 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAU82427.1 - 0.037 13.8 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAU82427.1 - 0.038 14.4 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EAU82427.1 - 0.054 13.4 0.0 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 EAU82427.1 - 0.075 12.9 0.3 0.36 10.7 0.1 2.2 3 0 0 3 3 3 0 NTPase YhdB PF14148.6 EAU82427.1 - 0.088 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 YhdB-like protein AAA_22 PF13401.6 EAU82427.1 - 0.12 12.6 0.2 1.2 9.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EAU82427.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EAU82427.1 - 0.33 10.3 1.4 0.76 9.1 0.2 2.0 1 1 1 2 2 2 0 KaiC Penaeidin PF05927.11 EAU82431.1 - 2.5 8.9 6.9 11 6.9 6.9 2.2 1 1 0 1 1 1 0 Penaeidin F-box-like PF12937.7 EAU82433.1 - 1.1e-07 31.6 0.4 2.8e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU82433.1 - 0.085 12.8 0.1 4.4 7.3 0.0 3.1 3 0 0 3 3 3 0 F-box domain Pheromone PF08015.11 EAU82434.2 - 7e-06 27.0 1.3 0.00038 21.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone F-box-like PF12937.7 EAU82436.2 - 2.1e-07 30.7 0.0 7.6e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU82436.2 - 0.081 13.4 12.3 3.4 8.2 0.1 5.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAU82436.2 - 0.18 11.3 1.8 28 4.2 0.0 3.6 2 2 2 4 4 4 0 Leucine-rich repeat CDC45 PF02724.14 EAU82437.1 - 0.0071 14.7 1.2 0.0084 14.5 1.2 1.1 1 0 0 1 1 1 1 CDC45-like protein BBS2_C PF14782.6 EAU82437.1 - 0.22 10.2 5.0 0.31 9.7 5.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal RAP1 PF07218.11 EAU82437.1 - 3 6.0 11.0 4.5 5.4 11.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_13 PF13166.6 EAU82437.1 - 7.6 5.0 10.1 10 4.6 10.1 1.1 1 0 0 1 1 1 0 AAA domain MRI PF15325.6 EAU82439.2 - 0.46 11.6 10.1 0.74 10.9 4.0 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection F-box-like PF12937.7 EAU82440.1 - 3.4e-06 26.8 0.0 7.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Type_III_YscG PF09477.10 EAU82440.1 - 0.2 11.8 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) F-box-like PF12937.7 EAU82441.2 - 0.00076 19.3 0.1 0.00076 19.3 0.1 1.9 2 0 0 2 2 2 1 F-box-like WD40 PF00400.32 EAU82442.1 - 4.4e-06 27.3 9.1 0.11 13.4 0.6 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat CDC45 PF02724.14 EAU82442.1 - 0.19 10.0 6.9 0.21 9.9 5.4 1.8 2 0 0 2 2 2 0 CDC45-like protein EF-hand_1 PF00036.32 EAU82443.2 - 9.2e-28 93.7 9.5 1.7e-06 27.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAU82443.2 - 1.3e-24 86.4 4.2 1.8e-14 53.9 0.8 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAU82443.2 - 4.8e-21 72.8 6.8 2.8e-05 23.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAU82443.2 - 1.3e-18 65.6 11.1 5.3e-06 25.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EAU82443.2 - 1.4e-11 44.0 14.0 0.00056 19.7 0.5 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 EAU82443.2 - 2e-06 27.7 5.6 0.0024 17.8 0.4 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAU82443.2 - 3e-06 27.5 0.0 0.011 16.0 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EAU82443.2 - 0.0052 17.1 0.1 1.4 9.3 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain Anthrax-tox_M PF09156.10 EAU82443.2 - 0.045 13.1 0.4 0.14 11.4 0.1 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain VCBS PF13517.6 EAU82443.2 - 0.14 12.8 1.3 19 5.9 0.4 2.5 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Dockerin_1 PF00404.18 EAU82443.2 - 0.16 12.2 5.1 0.15 12.3 1.8 2.6 2 2 1 3 3 3 0 Dockerin type I domain WD40 PF00400.32 EAU82444.1 - 5.7e-12 45.9 9.8 8.3e-07 29.6 1.2 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82444.1 - 3.8e-06 27.1 0.0 0.082 13.2 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAU82444.1 - 2e-05 24.6 1.2 0.0096 15.8 0.1 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EAU82444.1 - 0.0051 14.9 0.1 0.11 10.5 0.0 2.2 2 1 0 2 2 2 1 IKI3 family PTPRCAP PF15713.5 EAU82444.1 - 0.0062 16.8 0.4 0.013 15.7 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 EAU82445.1 - 0.034 13.5 3.9 0.039 13.3 3.9 1.1 1 0 0 1 1 1 0 BUD22 MRI PF15325.6 EAU82445.1 - 0.5 11.5 9.4 0.62 11.2 5.5 2.0 1 1 1 2 2 2 0 Modulator of retrovirus infection MitMem_reg PF13012.6 EAU82446.2 - 0.091 13.2 0.2 0.31 11.5 0.2 2.2 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function zf-C4H2 PF10146.9 EAU82446.2 - 0.15 12.4 5.2 1.2 9.4 4.8 2.7 1 1 0 1 1 1 0 Zinc finger-containing protein MCM6_C PF18263.1 EAU82446.2 - 0.35 11.1 2.4 2.1 8.6 0.2 2.4 2 0 0 2 2 2 0 MCM6 C-terminal winged-helix domain FapA PF03961.13 EAU82446.2 - 0.73 8.4 4.8 1.6 7.2 0.7 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF92 PF01940.16 EAU82447.2 - 0.017 14.6 0.3 0.026 13.9 0.3 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 UBA_3 PF09288.10 EAU82447.2 - 0.046 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain ING PF12998.7 EAU82448.2 - 0.018 15.6 0.8 0.018 15.6 0.8 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DHR10 PF18595.1 EAU82448.2 - 0.047 13.7 0.1 0.047 13.7 0.1 3.1 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain DUF5388 PF17363.2 EAU82448.2 - 0.17 12.1 2.7 0.27 11.5 0.1 2.6 2 2 0 2 2 2 0 Family of unknown function (DUF5388) CLZ PF16526.5 EAU82448.2 - 0.48 10.8 5.6 2.3 8.7 0.3 2.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1640 PF07798.11 EAU82448.2 - 0.62 10.1 7.9 0.17 11.9 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) PRKCSH-like PF12999.7 EAU82449.1 - 1.5e-54 184.5 2.5 1.6e-54 184.4 1.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EAU82449.1 - 1.2e-22 80.2 1.0 1.9e-22 79.6 0.0 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EAU82449.1 - 9.4e-13 49.0 0.9 2.7e-12 47.5 0.9 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 EAU82449.1 - 0.00078 19.6 15.0 0.052 13.8 2.1 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Cob_adeno_trans PF01923.18 EAU82449.1 - 0.022 14.9 1.7 0.37 10.9 0.4 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase BRE1 PF08647.11 EAU82449.1 - 0.042 13.9 14.4 0.84 9.8 0.2 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 EAU82449.1 - 0.091 12.1 10.7 0.17 11.2 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EAU82449.1 - 0.13 12.0 9.1 0.043 13.6 1.9 2.7 2 0 0 2 2 2 0 Septum formation initiator Phage_HK97_TLTM PF06120.11 EAU82449.1 - 0.3 10.2 5.8 6.8 5.8 0.1 2.2 2 0 0 2 2 2 0 Tail length tape measure protein Spc7 PF08317.11 EAU82449.1 - 0.35 9.7 12.1 1.1 8.1 8.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.11 EAU82449.1 - 0.79 10.0 7.6 8.1 6.7 2.7 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Exonuc_VII_L PF02601.15 EAU82449.1 - 0.82 9.2 6.2 1.1 8.8 3.7 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 EAU82449.1 - 0.93 9.9 14.9 4.2 7.8 0.7 2.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMF_TATA_bd PF12325.8 EAU82449.1 - 0.93 9.7 12.1 12 6.2 7.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.11 EAU82449.1 - 1.8 8.3 12.7 0.49 10.2 6.8 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 V_ATPase_I PF01496.19 EAU82449.1 - 1.9 6.3 3.6 3.4 5.5 3.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 EAU82449.1 - 2.7 6.8 3.2 24 3.7 1.7 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein Prefoldin_2 PF01920.20 EAU82449.1 - 3.1 7.8 11.7 0.5 10.3 3.6 2.8 2 0 0 2 2 2 0 Prefoldin subunit Atg14 PF10186.9 EAU82449.1 - 3.5 6.6 13.1 2.2 7.3 10.1 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PEP-utilisers_N PF05524.13 EAU82449.1 - 5.8 7.1 12.0 2.2 8.5 0.7 2.7 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal APG6_N PF17675.1 EAU82449.1 - 5.9 7.4 19.0 5.8 7.5 0.2 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region Ribosomal_S25 PF03297.15 EAU82450.2 - 6.3e-38 129.0 3.0 7.8e-38 128.8 3.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FGGY_C PF02782.16 EAU82451.2 - 3.8e-27 95.3 0.9 1.1e-26 93.8 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EAU82451.2 - 4.3e-16 59.2 0.2 1.8e-13 50.6 0.1 3.3 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain AnmK PF03702.14 EAU82451.2 - 0.00046 19.4 0.0 0.00081 18.6 0.0 1.3 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase BcrAD_BadFG PF01869.20 EAU82451.2 - 0.12 11.9 1.6 0.28 10.6 0.3 2.1 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MARVEL PF01284.23 EAU82453.1 - 2.9e-05 24.2 20.7 3.8e-05 23.8 20.3 1.3 1 1 0 1 1 1 1 Membrane-associating domain MBOAT PF03062.19 EAU82454.1 - 1.8e-52 178.8 5.2 6.3e-52 177.1 5.2 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Mito_carr PF00153.27 EAU82456.1 - 1e-56 188.8 6.1 2.4e-20 72.3 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein JmjC PF02373.22 EAU82457.2 - 5.3e-11 43.0 0.0 1.4e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EAU82457.2 - 1.4e-05 24.9 0.0 0.00027 20.7 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain C1_1 PF00130.22 EAU82457.2 - 0.048 13.6 2.2 0.12 12.3 2.2 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EAU82457.2 - 0.59 10.3 4.7 0.19 11.9 1.2 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger Prok-RING_2 PF14445.6 EAU82457.2 - 2.2 8.5 13.7 0.64 10.2 6.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Ribosomal_L18 PF17135.4 EAU82460.1 - 1.8e-88 294.9 3.4 2e-88 294.7 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EAU82460.1 - 0.00039 21.1 0.1 0.00093 19.9 0.1 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Adenylate_cycl PF01295.18 EAU82460.1 - 0.24 10.0 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I RRM_1 PF00076.22 EAU82461.2 - 3.4e-14 52.4 0.0 1.7e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAU82461.2 - 0.0068 16.0 0.0 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU82461.2 - 0.17 11.8 0.0 1.3 8.9 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif GN3L_Grn1 PF08701.11 EAU82462.2 - 2.6e-24 85.1 18.6 2.6e-24 85.1 18.6 2.9 3 0 0 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EAU82462.2 - 9.3e-16 57.9 0.6 4e-12 46.2 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU82462.2 - 1.5e-08 34.7 0.0 5.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EAU82462.2 - 9.6e-07 28.3 0.2 2.3e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 EAU82462.2 - 6.6e-06 25.7 0.0 0.0032 17.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EAU82462.2 - 1.8e-05 24.3 0.0 0.15 11.6 0.0 3.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Septin PF00735.18 EAU82462.2 - 0.00025 20.4 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EAU82462.2 - 0.00031 20.9 17.0 0.00097 19.2 0.2 4.4 4 2 1 5 5 5 2 Dynamin family IIGP PF05049.13 EAU82462.2 - 0.075 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) F-box-like PF12937.7 EAU82464.1 - 3.1e-08 33.4 0.8 3.9e-07 29.9 0.1 3.0 3 0 0 3 3 3 1 F-box-like ECR1_N PF14382.6 EAU82465.1 - 3e-15 55.7 0.3 5.4e-15 54.9 0.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EAU82465.1 - 8.7e-14 51.6 0.1 1.6e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EAU82465.1 - 0.069 13.8 0.1 1.1 9.9 0.1 2.3 1 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 PUF PF00806.19 EAU82466.1 - 6.9e-16 57.0 0.0 0.0062 16.2 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat Katanin_con80 PF13925.6 EAU82466.1 - 0.032 14.3 0.1 0.078 13.0 0.1 1.6 1 0 0 1 1 1 0 con80 domain of Katanin SCO1-SenC PF02630.14 EAU82467.1 - 1.1e-46 158.1 0.0 2.1e-46 157.1 0.0 1.5 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.21 EAU82467.1 - 8.2e-06 25.8 0.0 3.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EAU82467.1 - 0.038 14.3 0.0 0.065 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Ank_2 PF12796.7 EAU82468.2 - 3.7e-69 229.3 6.1 5.6e-19 68.5 0.3 7.0 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU82468.2 - 2.2e-55 178.1 3.9 3.5e-06 26.9 0.0 12.9 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.6 EAU82468.2 - 4.3e-50 167.5 7.9 1.5e-09 38.2 0.1 9.3 3 1 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU82468.2 - 2.5e-41 139.2 9.3 2.9e-07 30.6 0.0 10.8 1 1 11 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.30 EAU82468.2 - 8.2e-40 133.5 11.7 2.2e-06 27.8 0.1 12.4 11 1 1 12 12 12 7 Ankyrin repeat BRCA-2_helical PF09169.10 EAU82468.2 - 2.8e-05 23.9 0.3 0.094 12.4 0.0 4.1 4 1 1 5 5 5 1 BRCA2, helical AAA_22 PF13401.6 EAU82468.2 - 6.2e-05 23.3 0.0 0.00087 19.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAU82468.2 - 0.00081 18.7 0.0 0.002 17.4 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EAU82468.2 - 0.018 15.4 0.0 0.081 13.3 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain Nitro_FeMo-Co PF02579.17 EAU82468.2 - 0.042 14.2 6.3 1.6 9.1 0.1 4.7 2 2 4 6 6 6 0 Dinitrogenase iron-molybdenum cofactor DUF2075 PF09848.9 EAU82468.2 - 0.043 13.0 0.0 0.082 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EAU82468.2 - 0.052 13.5 0.2 0.48 10.3 0.0 2.7 3 1 0 3 3 3 0 NACHT domain DUF4988 PF16378.5 EAU82468.2 - 0.054 13.2 0.1 11 5.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function DUF2007 PF09413.10 EAU82468.2 - 0.077 13.2 1.2 13 6.1 0.0 4.5 4 1 1 5 5 5 0 Putative prokaryotic signal transducing protein OpuAC PF04069.12 EAU82468.2 - 0.13 11.8 1.7 5.5 6.5 0.0 3.6 3 1 1 4 4 4 0 Substrate binding domain of ABC-type glycine betaine transport system AAA PF00004.29 EAU82468.2 - 0.13 12.7 0.0 0.65 10.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NAD_binding_10 PF13460.6 EAU82471.1 - 1.3e-09 38.2 0.1 6.6e-08 32.7 0.1 2.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAU82471.1 - 0.00013 21.5 0.0 0.0086 15.6 0.0 2.6 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EAU82471.1 - 0.012 15.2 0.0 0.12 11.9 0.0 2.3 1 1 1 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 EAU82471.1 - 0.031 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain SEO_C PF14577.6 EAU82471.1 - 0.075 12.5 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Sieve element occlusion C-terminus PTR2 PF00854.21 EAU82472.1 - 3.8e-72 243.3 4.7 5.2e-72 242.9 4.7 1.1 1 0 0 1 1 1 1 POT family CcmH PF03918.14 EAU82472.1 - 3.7 6.9 5.1 8.8 5.6 0.0 3.1 2 1 1 3 3 3 0 Cytochrome C biogenesis protein F-box-like PF12937.7 EAU82477.1 - 9.4e-05 22.2 3.7 9.4e-05 22.2 3.7 2.4 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EAU82477.1 - 10 6.7 15.5 3.9 8.0 2.3 5.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Abhydrolase_1 PF00561.20 EAU82478.2 - 6.5e-09 35.8 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAU82478.2 - 8.7e-08 31.7 0.0 1.3e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU82478.2 - 6.4e-07 30.2 0.4 1e-06 29.6 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EAU82478.2 - 0.028 13.9 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S10 PF00450.22 EAU82478.2 - 0.072 12.5 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase F-box-like PF12937.7 EAU82479.2 - 2e-06 27.6 0.2 6.6e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like Actin PF00022.19 EAU82481.1 - 2.3e-146 487.6 0.0 1.2e-145 485.2 0.0 1.8 1 1 0 1 1 1 1 Actin p450 PF00067.22 EAU82482.2 - 4.6e-70 236.6 0.2 4.2e-67 226.9 0.2 2.1 1 1 0 1 1 1 1 Cytochrome P450 VWA_2 PF13519.6 EAU82483.1 - 4.7e-24 85.1 0.1 3.9e-23 82.1 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EAU82483.1 - 1.4e-05 25.0 0.1 3.6e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Ssl1-like UIM PF02809.20 EAU82483.1 - 3.7e-05 23.3 13.1 0.00012 21.8 4.2 4.4 5 0 0 5 5 5 3 Ubiquitin interaction motif DUF3138 PF11336.8 EAU82483.1 - 0.29 9.7 7.7 0.5 8.9 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NESP55 PF06390.12 EAU82483.1 - 2.7 7.5 15.3 4.7 6.7 15.3 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) MSP1_C PF07462.11 EAU82483.1 - 3.5 6.2 8.8 5 5.7 8.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CGI-121 PF08617.10 EAU82484.1 - 2.2e-51 174.2 0.9 2.5e-51 174.0 0.9 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.20 EAU82485.2 - 2.1e-52 175.4 0.1 3.8e-26 91.1 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EAU82485.2 - 6.5e-11 42.5 0.0 1.3e-05 25.2 0.0 4.2 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EAU82485.2 - 7.3e-09 36.1 0.2 0.0028 18.1 0.0 3.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAU82485.2 - 0.00017 21.9 0.4 0.33 11.3 0.0 4.7 4 2 1 5 5 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EAU82485.2 - 0.014 15.6 0.1 0.48 10.6 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin-like CDC45 PF02724.14 EAU82485.2 - 0.032 12.5 3.3 0.05 11.9 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SAM_3 PF18016.1 EAU82485.2 - 0.038 13.8 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RXT2_N PF08595.11 EAU82485.2 - 0.045 13.8 2.0 0.1 12.7 2.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal TraF PF13728.6 EAU82485.2 - 0.065 13.0 0.0 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 EAU82485.2 - 0.11 12.1 0.3 3.1 7.4 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin DinB PF05163.12 EAU82485.2 - 0.18 11.7 0.0 6 6.8 0.0 2.3 2 0 0 2 2 2 0 DinB family YL1 PF05764.13 EAU82485.2 - 0.19 11.8 3.0 0.33 11.0 3.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 EAU82485.2 - 0.54 10.1 4.6 1.2 9.0 4.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Utp14 PF04615.13 EAU82485.2 - 0.98 7.9 4.8 1.6 7.2 4.8 1.2 1 0 0 1 1 1 0 Utp14 protein TFIIF_alpha PF05793.12 EAU82485.2 - 1.4 7.4 10.3 2.4 6.6 10.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.12 EAU82485.2 - 2 7.6 12.6 3.9 6.7 12.6 1.4 1 0 0 1 1 1 0 NOA36 protein SGT1 PF07093.11 EAU82485.2 - 2.7 6.3 4.8 4.5 5.6 4.8 1.3 1 0 0 1 1 1 0 SGT1 protein Osteopontin PF00865.18 EAU82485.2 - 5 6.5 16.8 9.7 5.6 16.8 1.4 1 0 0 1 1 1 0 Osteopontin Cwf_Cwc_15 PF04889.12 EAU82485.2 - 6.7 6.4 15.5 18 4.9 15.5 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EAU82485.2 - 7.6 4.5 13.0 12 3.9 13.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EAU82485.2 - 8.6 4.4 7.0 13 3.8 7.0 1.2 1 0 0 1 1 1 0 Nop14-like family TPPK_C PF12555.8 EAU82488.1 - 0.18 11.9 1.0 0.33 11.0 1.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Penaeidin PF05927.11 EAU82489.1 - 0.1 13.4 0.1 0.16 12.7 0.1 1.3 1 0 0 1 1 1 0 Penaeidin F-box-like PF12937.7 EAU82491.2 - 0.00014 21.7 0.0 0.00038 20.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_9 PF14580.6 EAU82491.2 - 0.16 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat EMG1 PF03587.14 EAU82492.2 - 2.1e-76 255.9 0.0 2.8e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Filaggrin PF03516.13 EAU82492.2 - 0.028 15.1 21.3 0.094 13.4 9.1 2.7 2 0 0 2 2 2 0 Filaggrin F-box-like PF12937.7 EAU82495.1 - 0.0014 18.5 2.3 0.0016 18.3 0.1 2.3 3 0 0 3 3 3 1 F-box-like Pex24p PF06398.11 EAU82496.2 - 1.6e-15 57.0 13.8 1.2e-07 31.1 0.0 3.1 2 1 1 3 3 3 3 Integral peroxisomal membrane peroxin Phg_2220_C PF09524.10 EAU82497.2 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) F-box-like PF12937.7 EAU82500.2 - 6.3e-09 35.6 0.2 2.7e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU82500.2 - 0.00051 19.9 0.1 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAU82501.2 - 2.1e-05 24.3 0.2 7.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU82501.2 - 0.001 19.4 9.6 5.2 7.6 0.1 5.5 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 EAU82501.2 - 0.14 12.8 1.5 17 6.3 0.1 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat F-box PF00646.33 EAU82501.2 - 0.16 11.9 0.6 3.7 7.5 0.0 3.2 3 0 0 3 3 3 0 F-box domain SNF2_N PF00176.23 EAU82504.2 - 2e-12 46.5 0.0 1.7e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU82504.2 - 8.4e-09 35.8 0.6 2.8e-08 34.1 0.6 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EAU82504.2 - 2.2e-06 27.1 0.2 2.2e-06 27.1 0.2 2.1 2 1 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DUF5310 PF17237.2 EAU82507.2 - 0.16 11.9 1.2 0.32 10.9 1.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Pkinase_fungal PF17667.1 EAU82508.2 - 1.1e-09 37.6 0.3 0.0017 17.2 0.0 2.8 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 EAU82508.2 - 0.033 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tubulin_3 PF14881.6 EAU82508.2 - 0.097 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Tubulin domain Ku_PK_bind PF08785.11 EAU82508.2 - 0.17 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Ku C terminal domain like TMEM220 PF15071.6 EAU82509.2 - 0.67 10.7 0.1 0.67 10.7 0.1 2.6 3 0 0 3 3 3 0 Transmembrane family 220, helix Peptidase_M36 PF02128.15 EAU82511.2 - 2.8e-143 477.6 3.4 3.4e-143 477.3 3.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EAU82511.2 - 0.00045 20.0 0.1 0.00045 20.0 0.1 2.1 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif DUF1202 PF06717.11 EAU82511.2 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF1996 PF09362.10 EAU82513.2 - 1.2e-67 228.3 0.1 1.7e-67 227.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU82513.2 - 1.8e-09 37.4 8.6 1.8e-09 37.4 8.6 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain zf-C2H2 PF00096.26 EAU82516.1 - 1.3e-08 34.8 13.1 7.2e-05 23.0 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU82516.1 - 3.3e-05 24.1 15.6 0.0018 18.6 3.0 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU82516.1 - 0.0026 18.5 10.9 0.12 13.2 1.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EAU82516.1 - 0.009 16.6 2.9 0.13 12.9 0.4 2.4 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 EAU82516.1 - 0.067 13.0 0.7 0.28 11.0 0.7 2.1 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-met PF12874.7 EAU82516.1 - 2.4 8.7 13.0 3.2 8.3 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF1996 PF09362.10 EAU82517.2 - 6.1e-67 226.0 0.0 8e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MLTD_N PF06474.12 EAU82518.2 - 0.013 15.7 0.4 0.021 15.0 0.1 1.6 2 0 0 2 2 2 0 MltD lipid attachment motif DUF1996 PF09362.10 EAU82519.2 - 6e-39 134.4 2.4 4.4e-26 92.3 0.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) Coatomer_WDAD PF04053.14 EAU82527.2 - 7.3e-59 200.0 0.1 5.9e-58 197.0 0.0 2.3 2 1 0 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 EAU82527.2 - 6.6e-37 124.9 6.3 2.3e-06 28.2 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82527.2 - 1.3e-10 41.5 0.1 0.05 13.9 0.0 6.7 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EAU82527.2 - 0.00011 22.2 0.0 9 6.4 0.0 5.0 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EAU82527.2 - 0.0002 20.1 0.9 0.23 10.1 0.0 3.7 2 2 2 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EAU82527.2 - 0.0039 16.6 0.0 0.62 9.3 0.0 2.7 3 0 0 3 3 3 2 WD40-like domain SPT6_acidic PF14632.6 EAU82528.2 - 0.19 12.3 8.3 0.34 11.5 8.3 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Chitin_synth_2 PF03142.15 EAU82533.2 - 5.3e-212 705.1 0.8 7.7e-171 569.3 0.0 2.1 1 1 1 2 2 2 2 Chitin synthase Myosin_head PF00063.21 EAU82533.2 - 3.4e-69 233.8 0.0 3.6e-63 213.9 0.0 3.9 4 0 0 4 4 4 2 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.6 EAU82533.2 - 2.9e-16 60.0 0.0 1.1e-14 55.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 EAU82533.2 - 1.5e-15 56.8 0.3 3.2e-15 55.8 0.3 1.6 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EAU82533.2 - 1.4e-14 54.5 2.1 1.4e-14 54.5 2.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 EAU82533.2 - 4.3e-13 49.2 0.0 1.2e-08 34.9 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 EAU82533.2 - 5.3e-08 32.8 0.0 0.0003 20.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAU82533.2 - 1.7e-05 24.4 0.0 0.016 14.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 DUF1240 PF06836.12 EAU82534.2 - 0.44 11.1 3.8 0.34 11.4 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DLH PF01738.18 EAU82536.2 - 2.2e-14 53.5 0.0 2.8e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Mucin PF01456.17 EAU82536.2 - 8 6.4 29.1 17 5.4 29.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Multi_Drug_Res PF00893.19 EAU82537.2 - 0.053 14.2 1.4 0.099 13.3 1.4 1.5 1 1 0 1 1 1 0 Small Multidrug Resistance protein DUF4153 PF13687.6 EAU82537.2 - 3.8 7.1 9.6 1.1 8.9 1.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4153) TrkH PF02386.16 EAU82540.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Cation transport protein Shugoshin_N PF07558.11 EAU82542.2 - 0.084 12.8 1.1 0.14 12.1 1.1 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Transposase_21 PF02992.14 EAU82543.2 - 1.3e-05 24.6 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 EAU82543.2 - 0.046 13.3 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF2981 PF11200.8 EAU82543.2 - 0.96 9.1 5.8 2.1 8.0 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Lin-8 PF03353.15 EAU82543.2 - 4.8 6.7 9.4 8.6 5.8 9.4 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Coat_F PF07875.12 EAU82544.2 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Coat F domain ABC_tran PF00005.27 EAU82547.2 - 3.2e-41 141.0 0.0 1.6e-20 74.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EAU82547.2 - 5.3e-22 77.6 3.9 5.3e-22 77.6 3.9 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EAU82547.2 - 2.6e-15 57.0 1.2 0.00056 19.8 0.1 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU82547.2 - 5.2e-07 29.3 1.2 0.23 10.9 0.1 4.2 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU82547.2 - 9.4e-07 28.5 1.1 0.049 13.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EAU82547.2 - 4.5e-06 27.3 8.1 0.025 15.1 0.1 3.9 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EAU82547.2 - 3.3e-05 24.3 0.0 0.42 11.0 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EAU82547.2 - 0.00015 21.8 0.2 0.79 9.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 EAU82547.2 - 0.0015 19.1 0.0 3 8.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EAU82547.2 - 0.0016 18.2 3.3 1.9 8.1 0.2 3.7 2 2 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 EAU82547.2 - 0.0021 18.1 0.0 0.44 10.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EAU82547.2 - 0.0029 17.3 0.5 4.7 6.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 EAU82547.2 - 0.0036 17.6 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU82547.2 - 0.0053 16.5 0.0 1.8 8.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EAU82547.2 - 0.0064 16.4 1.9 0.35 10.8 0.1 2.8 3 0 0 3 3 3 1 RsgA GTPase RNA_helicase PF00910.22 EAU82547.2 - 0.017 15.5 2.3 9.8 6.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 EAU82547.2 - 0.019 14.6 0.3 8.4 5.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EAU82547.2 - 0.026 14.8 0.0 8.5 6.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EAU82547.2 - 0.029 14.4 5.2 2.4 8.2 0.0 3.9 2 1 1 3 3 3 0 Dynamin family FtsK_SpoIIIE PF01580.18 EAU82547.2 - 0.049 13.0 1.0 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EAU82547.2 - 0.056 13.7 0.0 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EAU82547.2 - 0.057 13.5 7.9 1.6 8.7 0.1 3.6 3 1 1 4 4 4 0 Helicase HerA, central domain AAA_14 PF13173.6 EAU82547.2 - 0.059 13.4 0.0 24 4.9 0.0 3.6 5 0 0 5 5 3 0 AAA domain NB-ARC PF00931.22 EAU82547.2 - 0.077 12.2 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EAU82547.2 - 0.095 12.9 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAU82547.2 - 0.12 12.7 0.0 26 5.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 EAU82547.2 - 0.13 11.4 2.2 13 4.8 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.15 EAU82547.2 - 0.15 12.0 0.1 3.6 7.5 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 EAU82547.2 - 0.16 11.9 0.0 20 5.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.12 EAU82547.2 - 0.49 9.8 7.7 13 5.2 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A32 protein DUF4395 PF14340.6 EAU82548.2 - 0.016 15.6 1.9 0.024 15.0 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) F-box PF00646.33 EAU82549.1 - 0.00025 20.9 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU82549.1 - 0.00058 19.7 0.3 0.0014 18.5 0.3 1.7 1 0 0 1 1 1 1 F-box-like MSA-2c PF12238.8 EAU82549.1 - 1.3 9.0 3.9 5.9 6.8 2.9 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c zf-MYND PF01753.18 EAU82551.2 - 3e-09 36.8 7.1 3e-09 36.8 7.1 2.1 2 0 0 2 2 2 1 MYND finger CxC5 PF18718.1 EAU82555.2 - 0.019 15.1 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases zinc_ribbon_10 PF10058.9 EAU82556.1 - 4.3e-21 74.4 0.4 6.5e-21 73.8 0.4 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein HOIP-UBA PF16678.5 EAU82556.1 - 0.012 15.6 0.6 0.025 14.6 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair GAPT PF11770.8 EAU82556.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Zn-ribbon_8 PF09723.10 EAU82556.1 - 0.11 12.6 0.5 0.22 11.7 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 EAU82556.1 - 3.6 7.6 4.9 28 4.7 4.9 2.1 1 1 0 1 1 1 0 PhnA Zinc-Ribbon SKI PF01202.22 EAU82558.2 - 0.15 12.2 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate kinase Adeno_E3_CR2 PF02439.15 EAU82559.2 - 0.097 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4536 PF15055.6 EAU82559.2 - 0.49 10.7 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) SKG6 PF08693.10 EAU82560.1 - 0.0047 16.3 0.2 0.0086 15.5 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.12 EAU82560.1 - 0.0094 16.1 0.1 0.017 15.3 0.1 1.3 1 0 0 1 1 1 1 Repeat of Unknown Function (DUF347) Stevor PF17410.2 EAU82560.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LapA_dom PF06305.11 EAU82560.1 - 1.1 9.1 3.6 1.9 8.3 3.6 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RicinB_lectin_2 PF14200.6 EAU82561.2 - 9.8e-08 32.6 3.2 1.1e-06 29.3 0.7 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU82561.2 - 4.1e-07 30.3 2.0 7.1e-07 29.5 0.8 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.22 EAU82562.1 - 5.5e-15 55.7 3.7 4.2e-13 49.7 3.9 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU82562.1 - 5.4e-12 46.3 3.7 0.00027 21.6 0.4 3.8 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 EAU82562.1 - 0.00026 20.6 0.4 0.071 12.7 0.1 2.9 1 1 1 2 2 2 2 Cytolethal distending toxin A/C domain GRDP-like PF07173.12 EAU82563.2 - 4.5e-20 72.8 4.0 8.9e-17 62.1 0.0 3.0 3 1 0 3 3 3 2 Glycine-rich domain-containing protein-like TRAF6_Z2 PF18048.1 EAU82563.2 - 0.028 14.5 0.6 0.073 13.2 0.6 1.7 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 DsbD_2 PF13386.6 EAU82566.2 - 1.4 8.8 12.7 0.018 15.0 3.9 2.2 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Circo_capsid PF02443.15 EAU82567.2 - 0.2 11.2 0.1 19 4.7 0.0 2.1 2 0 0 2 2 2 0 Circovirus capsid protein DLH PF01738.18 EAU82569.1 - 3e-06 26.9 0.0 4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family MSA-2c PF12238.8 EAU82569.1 - 0.11 12.5 1.1 0.17 11.8 1.1 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Pkinase_fungal PF17667.1 EAU82570.2 - 5.7e-26 91.2 0.0 5.5e-18 64.9 0.0 3.2 2 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU82570.2 - 0.00054 19.4 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU82570.2 - 0.0069 16.3 0.0 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAU82571.2 - 6.6e-27 94.3 0.0 4.1e-17 62.1 0.0 3.5 3 1 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 EAU82571.2 - 0.0014 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU82571.2 - 0.0024 17.8 0.0 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short_C2 PF13561.6 EAU82572.1 - 7.8e-52 176.2 0.2 9.9e-52 175.8 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU82572.1 - 2.2e-35 121.9 1.5 2.7e-35 121.6 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 EAU82572.1 - 0.0046 16.4 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Alk_phosphatase PF00245.20 EAU82572.1 - 0.011 14.7 0.3 0.016 14.1 0.3 1.1 1 0 0 1 1 1 0 Alkaline phosphatase F-box-like PF12937.7 EAU82573.1 - 2.3e-13 49.8 0.0 5.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU82573.1 - 0.00014 21.6 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 EAU82573.1 - 0.021 14.4 1.4 0.19 11.3 1.4 2.3 1 1 0 1 1 1 0 F-box RicinB_lectin_2 PF14200.6 EAU82577.2 - 1.3e-11 45.1 6.3 2.7e-10 40.9 1.8 2.4 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU82577.2 - 1.9e-10 41.1 4.7 1.4e-09 38.3 1.3 2.7 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain TraE PF05309.11 EAU82579.2 - 0.073 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 TraE protein Sugar_tr PF00083.24 EAU82583.1 - 2e-82 277.5 29.0 2.4e-82 277.2 29.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU82583.1 - 6.2e-29 101.0 50.8 3.1e-27 95.4 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAU82583.1 - 0.00042 18.9 5.5 0.00077 18.0 5.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EAU82583.1 - 0.039 12.3 11.9 2.3 6.4 1.0 3.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ubiquitin PF00240.23 EAU82584.2 - 2.4e-24 84.9 0.1 2.6e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAU82584.2 - 5.7e-13 48.5 0.4 6.2e-13 48.4 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EAU82584.2 - 8.1e-05 22.5 0.0 9.1e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EAU82584.2 - 0.00013 22.3 0.0 0.00029 21.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain His_Phos_2 PF00328.22 EAU82589.2 - 1e-37 130.5 0.0 1.5e-37 129.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SPT6_acidic PF14632.6 EAU82589.2 - 0.15 12.7 3.1 0.26 11.9 3.1 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 AMP-binding PF00501.28 EAU82590.1 - 4.5e-86 289.1 0.0 5.8e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU82590.1 - 9.4e-09 36.1 0.0 2.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Semialdhyde_dhC PF02774.18 EAU82596.1 - 4.9e-37 127.8 0.0 7e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EAU82596.1 - 4.9e-29 101.2 0.0 8.1e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Rab5ip PF07019.12 EAU82597.2 - 2.3e-20 73.0 3.5 2.8e-20 72.7 3.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_2 PF07719.17 EAU82600.1 - 1.3e-09 37.4 3.6 0.00085 19.3 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU82600.1 - 5.2e-09 35.5 0.0 0.0008 19.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU82600.1 - 2.1e-07 30.5 0.1 4e-05 23.2 0.0 3.5 4 0 0 4 4 4 1 TPR repeat TPR_9 PF13371.6 EAU82600.1 - 5.2e-06 26.5 0.5 0.035 14.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU82600.1 - 9.9e-06 26.1 4.3 0.0042 17.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAU82600.1 - 2.1e-05 24.9 0.3 0.47 11.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU82600.1 - 3.8e-05 23.9 0.1 0.15 12.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU82600.1 - 0.00016 21.6 0.0 0.46 10.8 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU82600.1 - 0.00018 21.3 3.9 0.23 11.6 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU82600.1 - 0.00028 21.4 12.5 0.0076 17.0 0.0 6.7 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAU82600.1 - 0.0006 19.6 3.9 0.041 13.8 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU82600.1 - 0.00068 19.8 0.2 1.3 9.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU82600.1 - 0.0091 16.2 0.0 2.2 8.6 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EAU82600.1 - 0.012 15.3 0.1 1 9.0 0.0 3.5 4 0 0 4 4 4 0 26S proteasome subunit RPN7 UAF_Rrn10 PF05234.11 EAU82602.2 - 0.001 19.3 0.0 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 UAF complex subunit Rrn10 FancD2 PF14631.6 EAU82602.2 - 0.18 9.2 0.9 0.23 8.8 0.9 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ribosomal_L13 PF00572.18 EAU82603.1 - 1.2e-51 174.2 0.0 1.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 zf_CCCH_4 PF18345.1 EAU82604.2 - 0.0001 22.2 3.8 0.00019 21.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EAU82604.2 - 0.0017 18.3 1.1 0.0028 17.5 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EAU82604.2 - 0.0036 17.1 2.3 0.0062 16.3 2.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Pkinase PF00069.25 EAU82605.1 - 1.6e-65 221.1 0.0 2e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU82605.1 - 4.6e-30 104.8 0.0 8.8e-30 103.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAU82605.1 - 0.029 13.3 0.1 0.04 12.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EAU82605.1 - 0.073 12.4 0.2 0.14 11.4 0.2 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EAU82605.1 - 0.08 12.9 0.2 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.7 EAU82606.2 - 4.3e-13 48.9 0.4 7.1e-12 45.0 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU82607.2 - 2.4e-11 43.3 0.3 5.5e-11 42.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EAU82607.2 - 0.097 12.5 0.2 0.097 12.5 0.2 3.5 4 0 0 4 4 4 0 Leucine rich repeat DivIC PF04977.15 EAU82607.2 - 0.47 10.2 1.4 0.98 9.2 1.4 1.5 1 0 0 1 1 1 0 Septum formation initiator F-box PF00646.33 EAU82607.2 - 1.1 9.3 4.4 2.6 8.0 0.3 3.1 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.7 EAU82607.2 - 9.4 6.8 8.4 5.7 7.5 2.1 3.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU82608.1 - 2.4e-10 40.2 0.9 4.8e-10 39.2 0.9 1.6 1 0 0 1 1 1 1 F-box-like DUF3375 PF11855.8 EAU82608.1 - 0.021 13.7 0.3 0.038 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) MerR-DNA-bind PF09278.11 EAU82608.1 - 0.035 14.6 0.3 0.11 13.0 0.3 1.9 1 0 0 1 1 1 0 MerR, DNA binding DUF1192 PF06698.11 EAU82608.1 - 0.1 12.7 0.3 0.3 11.2 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) F-box-like PF12937.7 EAU82610.2 - 4.4e-07 29.7 2.5 1.1e-06 28.4 2.5 1.7 1 0 0 1 1 1 1 F-box-like DivIC PF04977.15 EAU82610.2 - 0.0026 17.5 1.7 0.0048 16.6 1.7 1.3 1 0 0 1 1 1 1 Septum formation initiator MerR-DNA-bind PF09278.11 EAU82610.2 - 0.11 13.1 2.1 0.23 12.0 2.1 1.5 1 0 0 1 1 1 0 MerR, DNA binding FlxA PF14282.6 EAU82610.2 - 0.13 12.2 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 FlxA-like protein NUDIX PF00293.28 EAU82611.1 - 2.5e-13 50.2 0.0 4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DSPc PF00782.20 EAU82612.2 - 1.8e-32 111.9 0.0 1.1e-30 106.1 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAU82612.2 - 0.0044 16.6 0.0 0.0068 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EAU82612.2 - 0.028 14.7 0.0 0.058 13.7 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain p450 PF00067.22 EAU82615.2 - 1.9e-64 218.2 0.0 2.6e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF5323 PF17257.2 EAU82615.2 - 0.15 11.9 0.2 0.39 10.6 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5323) GST_N_3 PF13417.6 EAU82618.1 - 6.4e-21 74.6 0.1 1.5e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU82618.1 - 7.4e-12 45.4 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU82618.1 - 0.016 15.4 0.1 0.027 14.7 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAU82618.1 - 0.035 14.4 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU82618.1 - 0.082 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BTB PF00651.31 EAU82619.1 - 0.0022 18.2 0.1 0.0071 16.6 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain GAS PF13851.6 EAU82619.1 - 0.0086 15.4 18.2 0.014 14.7 18.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.6 EAU82619.1 - 0.028 14.0 14.7 0.016 14.8 11.7 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Gp-FAR-1 PF05823.12 EAU82619.1 - 0.036 14.4 4.3 0.076 13.4 4.3 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) GMC_oxred_C PF05199.13 EAU82619.1 - 0.093 13.3 0.4 0.21 12.1 0.4 1.6 1 0 0 1 1 1 0 GMC oxidoreductase Atg14 PF10186.9 EAU82619.1 - 0.49 9.4 9.8 0.86 8.6 9.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HALZ PF02183.18 EAU82619.1 - 0.57 10.4 5.0 2.6 8.3 5.1 2.0 1 1 0 1 1 1 0 Homeobox associated leucine zipper ApoLp-III PF07464.11 EAU82619.1 - 0.66 10.1 10.0 1.4 9.0 9.6 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.11 EAU82619.1 - 1.5 7.6 18.6 2.4 7.0 18.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 EAU82619.1 - 1.7 7.2 6.3 2.5 6.6 6.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 EAU82619.1 - 1.7 8.7 16.2 3.3 7.8 16.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cortex-I_coil PF09304.10 EAU82619.1 - 2.3 8.5 12.7 1.1 9.5 8.5 2.4 1 1 2 3 3 3 0 Cortexillin I, coiled coil BBP1_C PF15272.6 EAU82619.1 - 3.1 7.6 16.8 0.097 12.5 10.3 1.8 2 1 0 2 2 2 0 Spindle pole body component BBP1, C-terminal ARD PF03079.14 EAU82619.1 - 4.7 7.4 7.7 1.2 9.3 3.8 1.9 1 1 0 1 1 1 0 ARD/ARD' family TMPIT PF07851.13 EAU82619.1 - 5.4 6.2 9.3 11 5.1 9.3 1.5 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 EAU82619.1 - 8.9 4.7 6.8 11 4.3 6.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BST2 PF16716.5 EAU82619.1 - 9.5 6.9 16.0 3.7 8.2 8.3 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 GST_N_3 PF13417.6 EAU82620.1 - 1.6e-12 47.6 0.0 6.5e-12 45.7 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU82620.1 - 7.2e-10 39.0 0.0 2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU82620.1 - 7.7e-05 22.7 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU82620.1 - 0.0019 18.4 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU82620.1 - 0.0042 17.3 0.1 0.0084 16.3 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAU82620.1 - 0.059 13.7 0.1 0.56 10.6 0.0 2.5 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU82621.1 - 3.6e-12 46.5 0.0 8.2e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU82621.1 - 1e-11 44.9 0.1 4.3e-11 43.0 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU82621.1 - 6.1e-07 29.4 0.7 1.4e-06 28.2 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU82621.1 - 1.9e-06 28.0 0.1 6.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU82621.1 - 0.0009 19.4 0.1 0.0031 17.7 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EAU82621.1 - 0.052 14.3 0.0 0.46 11.2 0.0 2.2 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain F-box-like PF12937.7 EAU82628.1 - 2.9e-09 36.7 0.8 7.2e-09 35.4 0.8 1.7 1 0 0 1 1 1 1 F-box-like DivIC PF04977.15 EAU82628.1 - 0.041 13.6 0.6 0.088 12.6 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator F-box-like PF12937.7 EAU82629.2 - 5.9e-16 58.1 0.6 5.9e-16 58.1 0.6 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU82629.2 - 0.00057 20.2 0.1 1.3 9.5 0.1 4.7 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) FlxA PF14282.6 EAU82629.2 - 0.15 12.0 0.3 0.28 11.2 0.3 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF349 PF03993.12 EAU82629.2 - 0.16 12.3 0.3 0.32 11.3 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) tRNA-synt_1g PF09334.11 EAU82630.2 - 2.4e-66 224.1 0.0 3e-65 220.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EAU82630.2 - 1.4e-11 43.4 0.3 1.8e-09 36.5 0.0 2.9 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EAU82630.2 - 1.1e-07 31.6 0.2 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EAU82630.2 - 0.00024 21.1 0.0 0.0055 16.7 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA LacI PF00356.21 EAU82630.2 - 0.12 12.2 0.1 24 4.8 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF4448 PF14610.6 EAU82631.1 - 0.041 13.7 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rax2 PF12768.7 EAU82632.2 - 0.0086 15.6 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF1180 PF06679.12 EAU82632.2 - 0.022 15.2 0.0 0.059 13.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2207 PF09972.9 EAU82632.2 - 0.054 12.3 0.0 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 EAU82632.2 - 0.081 12.8 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF4672 PF15716.5 EAU82632.2 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) SOXp PF12336.8 EAU82632.2 - 7.5 7.7 7.1 93 4.2 7.1 2.5 1 1 0 1 1 1 0 SOX transcription factor F-box-like PF12937.7 EAU82633.1 - 0.11 12.4 0.7 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 F-box-like Phage_SSB PF16773.5 EAU82636.1 - 0.082 13.0 0.0 2.5 8.2 0.0 2.0 1 1 1 2 2 2 0 Lactococcus phage single-stranded DNA binding protein Nas2_N PF18265.1 EAU82637.2 - 0.94 9.4 2.9 2 8.4 0.0 2.7 3 0 0 3 3 3 0 Nas2 N_terminal domain F-box-like PF12937.7 EAU82638.2 - 3.5e-09 36.4 0.6 8.7e-09 35.1 0.6 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU82638.2 - 0.0039 17.6 1.7 3 8.4 0.0 4.2 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) DivIC PF04977.15 EAU82638.2 - 0.29 10.9 1.9 0.27 11.0 0.5 1.7 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 EAU82639.1 - 1.2e-11 44.3 0.5 2.9e-11 43.1 0.5 1.7 1 0 0 1 1 1 1 F-box-like MerR-DNA-bind PF09278.11 EAU82639.1 - 0.013 16.1 0.9 0.045 14.3 0.7 2.1 2 0 0 2 2 2 0 MerR, DNA binding DUF1102 PF06510.11 EAU82639.1 - 0.032 14.4 0.1 0.075 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1102) DivIC PF04977.15 EAU82639.1 - 3.7 7.4 4.6 1.8 8.4 2.0 1.7 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 EAU82640.1 - 3e-10 39.8 0.9 3e-10 39.8 0.9 2.5 3 0 0 3 3 3 1 F-box-like FlxA PF14282.6 EAU82640.1 - 0.19 11.7 1.3 0.3 11.1 1.3 1.3 1 0 0 1 1 1 0 FlxA-like protein HMG_box PF00505.19 EAU82642.2 - 0.0029 18.0 0.0 0.0029 18.0 0.0 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box DUF442 PF04273.13 EAU82643.2 - 0.093 12.8 0.7 8.7 6.5 0.0 3.1 3 2 0 3 3 3 0 Putative phosphatase (DUF442) GST_N_3 PF13417.6 EAU82645.1 - 1.3e-13 51.1 0.8 4.6e-13 49.4 0.8 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU82645.1 - 5e-11 42.7 0.0 9.3e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU82645.1 - 5.1e-06 26.4 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAU82645.1 - 0.063 13.6 0.1 1.6 9.1 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU82646.1 - 3e-13 50.0 0.2 9.1e-13 48.4 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU82646.1 - 5.8e-09 36.1 0.0 1.8e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU82646.1 - 0.033 14.2 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TMEM51 PF15345.6 EAU82647.2 - 0.00094 19.1 0.0 0.00094 19.1 0.0 1.6 2 0 0 2 2 2 1 Transmembrane protein 51 SARAF PF06682.12 EAU82647.2 - 0.011 15.4 5.0 0.016 14.9 5.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF1180 PF06679.12 EAU82647.2 - 0.017 15.6 0.4 0.017 15.6 0.4 3.0 1 1 1 2 2 1 0 Protein of unknown function (DUF1180) DUF5305 PF17231.2 EAU82647.2 - 0.022 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4381 PF14316.6 EAU82647.2 - 0.025 14.8 0.1 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Orf78 PF06024.12 EAU82647.2 - 0.043 14.1 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Orf78 (ac78) DUF4131 PF13567.6 EAU82647.2 - 0.075 12.7 1.1 8.6 6.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Herpes_gE PF02480.16 EAU82647.2 - 0.1 11.3 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MASE1 PF05231.14 EAU82647.2 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 MASE1 TMEM154 PF15102.6 EAU82647.2 - 0.23 11.4 1.9 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family LapA_dom PF06305.11 EAU82647.2 - 0.3 10.9 0.7 0.73 9.7 0.7 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Miga PF10265.9 EAU82647.2 - 0.37 9.7 6.2 0.28 10.1 3.3 1.8 1 1 1 2 2 2 0 Mitoguardin DUF3614 PF12267.8 EAU82647.2 - 0.59 10.6 0.0 0.59 10.6 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3614) Rootletin PF15035.6 EAU82648.2 - 0.00075 19.6 2.4 0.00075 19.6 2.4 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF1515 PF07439.11 EAU82648.2 - 0.031 14.3 0.6 0.08 13.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) GIT_CC PF16559.5 EAU82648.2 - 0.16 11.9 3.9 2.7 7.9 0.7 3.0 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TFIIA PF03153.13 EAU82648.2 - 0.27 11.2 10.0 0.34 10.9 1.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.11 EAU82648.2 - 0.98 9.6 25.8 0.78 9.9 3.9 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) WD40_alt PF14077.6 EAU82648.2 - 2.8 7.9 4.5 8.1 6.4 0.3 2.9 1 1 1 2 2 2 0 Alternative WD40 repeat motif FAM76 PF16046.5 EAU82648.2 - 4.2 6.6 10.8 0.57 9.5 3.2 2.2 2 0 0 2 2 2 0 FAM76 protein DivIC PF04977.15 EAU82648.2 - 4.6 7.1 13.5 3.3 7.5 2.0 3.5 2 1 2 4 4 4 0 Septum formation initiator DUF3446 PF11928.8 EAU82648.2 - 5 7.5 10.6 0.95 9.8 0.3 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain PspA_IM30 PF04012.12 EAU82648.2 - 6.4 6.3 13.9 2 8.0 8.3 2.5 2 1 0 2 2 2 0 PspA/IM30 family ZapB PF06005.12 EAU82648.2 - 9.6 6.7 18.4 33 5.0 11.1 3.7 2 1 1 3 3 3 0 Cell division protein ZapB DNA_ligase_OB_2 PF14743.6 EAU82651.2 - 6.5e-28 96.6 0.3 1.4e-27 95.5 0.3 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 EAU82651.2 - 2.4e-13 50.2 0.0 6.4e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EAU82651.2 - 3e-06 27.6 0.0 7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 RNA ligase DUF3246 PF11596.8 EAU82651.2 - 4.4 6.7 6.4 0.81 9.1 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) FixS PF03597.15 EAU82652.1 - 0.81 9.4 4.7 1.6 8.5 4.7 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Cu_amine_oxid PF01179.20 EAU82653.2 - 6.9e-82 275.5 0.0 4.5e-40 137.8 0.0 3.1 2 1 1 3 3 3 3 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EAU82653.2 - 7.6e-11 41.6 0.1 2.1e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EAU82653.2 - 6.7e-07 29.5 0.0 4.2e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 EAU82654.2 - 1.4e-110 370.1 0.1 1.9e-110 369.6 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain SAP18 PF06487.12 EAU82654.2 - 1.1e-32 113.1 0.0 1.9e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF1965 PF09248.10 EAU82654.2 - 9.6e-08 31.7 0.0 2.8e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EAU82654.2 - 0.0019 18.4 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Corona_nucleoca PF00937.18 EAU82654.2 - 0.71 8.8 5.8 1.2 8.1 5.8 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2457 PF10446.9 EAU82654.2 - 7.5 5.6 8.8 12 4.9 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Arrestin_N PF00339.29 EAU82656.1 - 2e-07 31.2 0.0 2.5e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Peptidase_M35 PF02102.15 EAU82657.2 - 2.5e-21 76.0 16.4 7.5e-21 74.4 16.4 1.7 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EAU82657.2 - 7.5e-21 75.2 2.0 1.4e-20 74.3 2.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EAU82657.2 - 2.3e-05 24.1 0.5 3.6e-05 23.5 0.5 1.3 1 0 0 1 1 1 1 Putative peptidase family CARDB PF07705.11 EAU82657.2 - 0.002 18.3 0.9 0.0056 16.9 0.1 2.2 2 0 0 2 2 2 1 CARDB Abhydrolase_1 PF00561.20 EAU82658.2 - 7.9e-19 68.3 0.2 5.8e-18 65.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAU82658.2 - 1e-17 64.3 0.1 2.7e-17 62.9 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU82658.2 - 2.7e-17 64.1 1.4 4e-17 63.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 EAU82658.2 - 9e-06 24.6 0.0 0.013 14.2 0.0 2.3 3 0 0 3 3 3 2 Ndr family Peptidase_S9 PF00326.21 EAU82658.2 - 0.00046 19.7 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EAU82658.2 - 0.00072 19.2 0.0 0.024 14.2 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EAU82658.2 - 0.001 18.8 0.1 1.4 8.7 0.0 3.0 3 0 0 3 3 3 2 Alpha/beta hydrolase family BAAT_C PF08840.11 EAU82658.2 - 0.004 17.1 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 EAU82658.2 - 0.022 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Peptidase_S28 PF05577.12 EAU82658.2 - 0.034 12.9 0.0 0.07 11.9 0.0 1.6 2 0 0 2 2 2 0 Serine carboxypeptidase S28 AidB_N PF18158.1 EAU82658.2 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Adaptive response protein AidB N-terminal domain Ribosomal_L7Ae PF01248.26 EAU82659.1 - 7.7e-27 92.9 2.8 9.4e-27 92.6 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.32 EAU82660.2 - 3.1e-18 65.8 22.5 1.2e-07 32.3 1.0 6.4 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82660.2 - 1.6e-08 34.7 0.2 0.00022 21.5 0.1 4.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EAU82660.2 - 0.00016 20.1 0.0 0.00025 19.5 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EAU82660.2 - 0.00093 18.6 0.4 1.9 7.7 0.0 3.3 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 EAU82660.2 - 0.0052 14.9 0.0 0.0081 14.2 0.0 1.2 1 0 0 1 1 1 1 IKI3 family PD40 PF07676.12 EAU82660.2 - 0.052 13.5 7.8 17 5.5 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EAU82660.2 - 0.063 12.2 0.3 1.8 7.5 0.1 3.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TruB_C PF09142.11 EAU82660.2 - 0.069 12.9 0.0 0.37 10.6 0.0 2.3 1 1 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal VID27 PF08553.10 EAU82660.2 - 0.24 10.4 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain WD40_like PF17005.5 EAU82660.2 - 0.25 10.6 0.0 11 5.2 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain WW PF00397.26 EAU82661.1 - 0.00036 20.6 0.3 0.00076 19.5 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF3095 PF11294.8 EAU82661.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) AT_hook PF02178.19 EAU82662.1 - 0.67 10.0 23.1 0.19 11.7 2.7 3.9 3 0 0 3 3 3 0 AT hook motif fn3_2 PF16893.5 EAU82663.1 - 5.7e-39 132.1 0.1 1.1e-38 131.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EAU82663.1 - 6e-26 90.1 0.1 1e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 EAU82663.1 - 2e-08 34.5 0.0 3.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EAU82663.1 - 2.9e-07 30.3 0.0 1.8e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 EAU82663.1 - 0.00067 19.8 0.1 0.0018 18.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EAU82663.1 - 0.001 19.4 0.2 0.0042 17.4 0.2 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 EAU82663.1 - 0.0025 18.2 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain F-box-like PF12937.7 EAU82664.1 - 7.4e-11 41.8 1.1 1.6e-10 40.7 1.1 1.6 1 0 0 1 1 1 1 F-box-like SMC_N PF02463.19 EAU82665.1 - 4.6e-21 75.3 0.2 6.7e-21 74.7 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAU82665.1 - 1.5e-10 41.9 25.6 1.5e-10 41.9 25.6 5.7 3 2 1 4 4 3 1 AAA domain AAA_15 PF13175.6 EAU82665.1 - 0.00017 21.5 11.2 0.00017 21.5 11.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EAU82665.1 - 0.00024 21.0 6.6 0.0023 17.8 0.3 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system HALZ PF02183.18 EAU82665.1 - 0.0016 18.7 11.3 0.14 12.4 1.5 5.6 5 0 0 5 5 5 1 Homeobox associated leucine zipper AAA_29 PF13555.6 EAU82665.1 - 0.0039 16.9 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 EAU82665.1 - 0.0073 16.3 11.9 1.2 9.1 0.1 5.9 6 1 1 7 7 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.8 EAU82665.1 - 0.021 15.1 1.2 4.2 7.7 0.0 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) IstB_IS21 PF01695.17 EAU82665.1 - 0.022 14.5 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4201 PF13870.6 EAU82665.1 - 0.047 13.4 0.2 0.047 13.4 0.2 7.1 4 2 2 6 6 5 0 Domain of unknown function (DUF4201) Phage_int_SAM_2 PF12834.7 EAU82665.1 - 0.15 12.8 2.7 5.3 7.8 0.0 4.3 3 0 0 3 3 3 0 Phage integrase, N-terminal TcpS PF17456.2 EAU82665.1 - 0.16 12.0 0.1 0.16 12.0 0.1 3.9 4 2 1 5 5 4 0 Toxin-coregulated pilus protein S AAA PF00004.29 EAU82665.1 - 0.45 10.9 0.0 0.45 10.9 0.0 3.6 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EAU82665.1 - 0.78 9.3 0.0 0.78 9.3 0.0 5.0 4 2 0 4 4 4 0 AAA domain DUF2443 PF10398.9 EAU82665.1 - 3.4 7.8 6.1 15 5.7 0.2 4.9 4 2 2 6 6 6 0 Protein of unknown function (DUF2443) Occludin_ELL PF07303.13 EAU82665.1 - 6 7.7 40.3 0.58 10.9 0.9 6.7 4 1 3 7 7 7 0 Occludin homology domain DUF4094 PF13334.6 EAU82665.1 - 6.8 7.2 24.8 0.034 14.6 3.1 5.3 5 1 0 5 5 4 0 Domain of unknown function (DUF4094) RNase_PH PF01138.21 EAU82666.1 - 1.9e-09 38.1 0.0 5.5e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EAU82666.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 HECW1_helix PF18436.1 EAU82667.1 - 0.2 11.8 1.5 0.46 10.6 0.2 2.0 2 0 0 2 2 2 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 SPX PF03105.19 EAU82667.1 - 4.8 7.0 20.1 6.7 6.5 20.1 1.2 1 0 0 1 1 1 0 SPX domain F-box-like PF12937.7 EAU82669.1 - 6.3e-08 32.4 5.1 6.9e-08 32.3 0.4 3.2 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EAU82669.1 - 0.0065 16.9 14.3 0.11 12.9 0.6 6.4 5 1 3 8 8 8 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAU82669.1 - 0.07 12.6 0.0 0.59 9.6 0.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat TAF4 PF05236.14 EAU82670.2 - 2.4e-32 112.8 5.0 2.4e-32 112.8 5.0 2.3 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF1682 PF07946.14 EAU82670.2 - 0.14 11.3 1.4 0.28 10.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pkinase PF00069.25 EAU82671.2 - 9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAU82671.2 - 0.0028 17.0 0.3 0.0048 16.3 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU82671.2 - 0.025 14.5 0.4 3.6 7.4 0.5 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.7 EAU82672.1 - 3.7e-11 42.7 0.8 1.1e-10 41.2 0.8 1.9 1 0 0 1 1 1 1 F-box-like zf-dskA_traR PF01258.17 EAU82672.1 - 0.22 11.5 0.7 0.5 10.3 0.2 1.8 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger F-box-like PF12937.7 EAU82673.1 - 1.9e-10 40.4 1.1 7.3e-10 38.6 1.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU82673.1 - 0.068 13.6 3.9 37 4.9 0.5 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF1992 PF09350.10 EAU82674.2 - 7.3e-22 77.3 0.1 2.7e-21 75.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Fe_bilin_red PF05996.12 EAU82674.2 - 0.06 13.0 0.4 4.9 6.8 0.2 2.1 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase UCH PF00443.29 EAU82675.1 - 4.5e-31 108.3 0.0 6.8e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAU82675.1 - 4e-06 26.7 0.0 2.9e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 EAU82676.2 - 6.8e-21 74.8 0.0 2.8e-12 46.6 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EAU82676.2 - 0.00034 20.0 0.0 0.13 11.5 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase AAR2 PF05282.11 EAU82676.2 - 0.042 13.2 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 AAR2 protein Vps36_ESCRT-II PF11605.8 EAU82678.1 - 0.00011 22.3 0.0 0.00037 20.6 0.0 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 EAU82678.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 GRAM domain p450 PF00067.22 EAU82679.2 - 3.3e-40 138.2 0.0 3.8e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EAU82680.2 - 7.5e-08 32.1 3.8 2.6e-07 30.4 3.8 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EAU82680.2 - 0.0021 17.8 1.9 2.3 8.1 0.1 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EAU82680.2 - 0.031 14.7 4.7 17 6.0 0.1 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAU82680.2 - 0.037 14.5 6.5 1.7 9.5 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.7 EAU82681.1 - 4e-11 42.6 2.0 4e-11 42.6 2.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU82681.1 - 0.00034 20.4 4.2 0.002 17.9 4.2 2.4 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EAU82681.1 - 0.59 10.6 10.0 24 5.5 1.5 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) RRP7 PF12923.7 EAU82682.1 - 2.9e-31 108.1 7.6 2.9e-31 108.1 7.6 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EAU82682.1 - 3.4e-13 49.7 0.6 6.4e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 EAU82682.1 - 8.6e-05 22.3 0.0 0.0014 18.4 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU82682.1 - 0.13 12.4 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif DUF5093 PF17011.5 EAU82682.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF5093) Aspzincin_M35 PF14521.6 EAU82683.2 - 2.5e-18 67.0 2.2 3.8e-18 66.4 2.2 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EAU82683.2 - 2e-14 53.2 4.6 2.2e-14 53.1 4.6 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 EAU82683.2 - 2.4e-06 27.3 0.4 3.7e-06 26.7 0.4 1.3 1 1 0 1 1 1 1 Putative peptidase family Band_7 PF01145.25 EAU82684.1 - 7e-23 81.5 4.6 1.1e-22 80.9 4.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Piwi PF02171.17 EAU82685.2 - 1.5e-73 247.7 0.0 2.2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 EAU82685.2 - 9.2e-15 54.7 0.0 4.2e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 EAU82685.2 - 9.3e-15 54.0 0.4 3.3e-14 52.3 0.4 2.0 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 EAU82685.2 - 4.6e-09 36.4 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoN PF16486.5 EAU82685.2 - 7.7e-06 26.6 0.0 2.9e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute 4HBT PF03061.22 EAU82686.2 - 1.6e-08 34.8 0.0 2.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DASH_Spc19 PF08287.11 EAU82687.1 - 3.2e-26 92.1 5.9 8.8e-25 87.4 5.1 2.0 1 1 0 1 1 1 1 Spc19 bZIP_1 PF00170.21 EAU82692.2 - 2 8.6 11.9 3.3 7.9 1.3 3.8 3 0 0 3 3 3 0 bZIP transcription factor RRM_1 PF00076.22 EAU82695.2 - 2.6e-33 113.6 0.0 2.3e-16 59.4 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAU82695.2 - 1.4e-05 25.0 0.0 5.5e-05 23.2 0.0 1.9 1 1 1 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EAU82695.2 - 0.00073 19.5 0.0 0.0037 17.2 0.0 2.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAU82695.2 - 0.0013 18.8 0.0 0.69 10.1 0.0 3.2 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 EAU82695.2 - 0.042 13.5 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU82695.2 - 0.089 12.7 0.0 0.61 10.0 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif F-box-like PF12937.7 EAU82696.2 - 6.9e-05 22.7 0.5 0.00019 21.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like TSC22 PF01166.18 EAU82696.2 - 0.0065 16.8 0.1 0.038 14.3 0.0 2.3 2 0 0 2 2 2 1 TSC-22/dip/bun family F-box-like PF12937.7 EAU82697.1 - 0.03 14.2 0.0 0.09 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box-like IFP_35_N PF07334.13 EAU82697.1 - 0.26 11.4 1.0 0.58 10.3 1.0 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus F-box-like PF12937.7 EAU82701.2 - 1.4e-11 44.1 1.2 2.6e-11 43.2 1.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU82701.2 - 0.00076 19.3 0.2 0.0018 18.1 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU82702.1 - 5.7e-11 42.1 0.1 1.4e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF2723 PF11028.8 EAU82702.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Na_H_Exchanger PF00999.21 EAU82703.1 - 2e-53 181.6 48.4 2.8e-53 181.1 48.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G10 PF01125.17 EAU82704.1 - 2.5e-68 228.5 6.8 2.7e-68 228.3 6.8 1.0 1 0 0 1 1 1 1 G10 protein TB2_DP1_HVA22 PF03134.19 EAU82705.2 - 7.1e-12 45.1 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CCDC53 PF10152.9 EAU82706.1 - 2.7 8.4 4.8 6 7.3 0.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex MWFE PF15879.5 EAU82707.1 - 2e-21 75.9 0.0 2.4e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Lip_prot_lig_C PF10437.9 EAU82708.2 - 6.4e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus CX9C PF16860.5 EAU82710.1 - 0.0019 18.2 11.5 0.33 11.0 0.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EAU82710.1 - 0.0025 17.9 4.0 0.0025 17.9 4.0 2.8 1 1 2 3 3 3 2 CHCH domain PBP_GOBP PF01395.22 EAU82710.1 - 0.0047 17.1 1.2 0.0047 17.1 1.2 1.4 2 0 0 2 2 2 1 PBP/GOBP family Pet191_N PF10203.9 EAU82710.1 - 0.23 11.8 12.7 0.97 9.8 8.8 2.8 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 EAU82710.1 - 6.7 7.0 13.0 1.1 9.5 6.0 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 EAU82710.1 - 9.6 6.3 15.5 32 4.7 3.1 2.7 1 1 3 4 4 4 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF498 PF04430.14 EAU82712.1 - 1.9e-34 118.0 0.0 2.4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Clathrin PF00637.20 EAU82714.2 - 2.7e-26 92.2 0.5 5.5e-26 91.2 0.5 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.32 EAU82714.2 - 0.0031 18.3 0.0 0.012 16.5 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Vps39_1 PF10366.9 EAU82714.2 - 0.0067 16.7 1.4 0.69 10.2 0.1 3.1 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Histone PF00125.24 EAU82714.2 - 0.27 11.6 1.2 0.78 10.1 1.2 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 zf-RING_2 PF13639.6 EAU82714.2 - 0.72 10.2 1.7 46 4.5 0.1 2.5 2 0 0 2 2 2 0 Ring finger domain DNA_pol_phi PF04931.13 EAU82714.2 - 3.9 5.4 34.7 9 4.3 34.7 1.5 1 0 0 1 1 1 0 DNA polymerase phi LRR_4 PF12799.7 EAU82715.1 - 0.2 12.2 4.3 44 4.7 0.8 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Alpha_kinase PF02816.18 EAU82716.1 - 2.5e-24 86.4 0.0 3.9e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family zinc-ribbons_6 PF07191.12 EAU82716.1 - 1.4 9.0 5.6 3.8 7.6 5.6 1.7 1 0 0 1 1 1 0 zinc-ribbons TackOD1 PF18551.1 EAU82716.1 - 2.9 7.5 7.5 1.6 8.4 1.0 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF3375 PF11855.8 EAU82719.1 - 0.0038 16.2 0.1 0.0043 16.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) F-box-like PF12937.7 EAU82719.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF1192 PF06698.11 EAU82719.1 - 0.059 13.4 0.1 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MerR-DNA-bind PF09278.11 EAU82719.1 - 0.075 13.6 0.1 0.095 13.3 0.1 1.2 1 0 0 1 1 1 0 MerR, DNA binding DUF3435 PF11917.8 EAU82720.1 - 0.021 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FAM216B PF15107.6 EAU82720.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 FAM216B protein family F-box-like PF12937.7 EAU82726.2 - 7.8e-14 51.3 1.0 1.5e-13 50.4 1.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU82726.2 - 0.2 11.5 4.6 0.41 10.6 0.4 3.1 2 1 0 2 2 2 0 F-box domain FAD_binding_4 PF01565.23 EAU82727.1 - 6.9e-29 100.4 4.2 6.9e-29 100.4 4.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EAU82727.1 - 1.3e-08 34.8 0.1 2.9e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EAU82728.1 - 1.8e-31 108.8 3.6 6.1e-31 107.0 2.6 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EAU82728.1 - 5.9e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Hemocyanin_N PF03722.14 EAU82728.1 - 0.011 16.2 0.0 0.086 13.4 0.0 2.1 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain Arb1 PF09692.10 EAU82729.1 - 0.00016 21.0 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PH PF00169.29 EAU82730.2 - 1.3e-12 48.2 0.1 3.6e-12 46.7 0.1 1.8 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 EAU82730.2 - 2.2e-12 46.9 0.0 3.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EAU82730.2 - 9.2e-11 42.0 0.1 2.1e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EAU82730.2 - 4.5e-05 23.2 0.1 0.00028 20.7 0.1 2.3 1 1 0 1 1 1 1 Variant SH3 domain SAM_3 PF18016.1 EAU82730.2 - 0.00051 19.8 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 EAU82730.2 - 0.015 14.9 0.1 0.07 12.7 0.1 2.2 1 1 0 1 1 1 0 SH3 domain SAM_Ste50p PF09235.10 EAU82730.2 - 0.018 15.3 0.3 0.036 14.3 0.3 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EAU82730.2 - 0.2 11.7 0.2 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF4470 PF14737.6 EAU82731.1 - 1.3e-20 73.4 0.0 3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EAU82731.1 - 3.2e-10 39.9 13.1 6.8e-10 38.9 13.1 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU82731.1 - 0.19 12.0 9.9 0.41 11.0 9.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 EAU82732.1 - 1.3e-07 31.4 2.4 4.7e-07 29.6 2.4 2.0 1 0 0 1 1 1 1 F-box-like CM_2 PF01817.21 EAU82732.1 - 0.088 13.2 0.1 2 8.8 0.1 2.6 2 0 0 2 2 2 0 Chorismate mutase type II F-box-like PF12937.7 EAU82734.2 - 7.4e-11 41.8 1.7 1.8e-10 40.5 1.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU82734.2 - 0.15 11.9 2.5 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 F-box domain YL1 PF05764.13 EAU82734.2 - 0.16 12.1 1.9 0.32 11.1 1.9 1.6 1 0 0 1 1 1 0 YL1 nuclear protein LRR_4 PF12799.7 EAU82734.2 - 4.2 7.9 10.2 23 5.6 0.2 4.7 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) MIG-14_Wnt-bd PF06664.12 EAU82735.1 - 0.058 12.6 4.0 0.37 10.0 0.1 2.3 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion SLY PF12485.8 EAU82736.1 - 0.25 12.1 1.6 0.47 11.2 1.6 1.4 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein F-box-like PF12937.7 EAU82737.1 - 1.2e-09 37.9 0.8 2.6e-09 36.8 0.8 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EAU82738.1 - 3.5e-31 106.8 9.0 4.6e-05 24.1 0.0 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82738.1 - 1.1e-14 54.4 0.0 0.00025 21.3 0.0 5.0 3 3 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAU82738.1 - 0.003 17.4 0.0 0.2 11.5 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EAU82738.1 - 0.0038 15.8 0.1 0.05 12.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 EAU82738.1 - 0.016 14.6 0.0 2.6 7.3 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Frtz PF11768.8 EAU82738.1 - 0.079 11.3 0.0 0.56 8.5 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Cullin PF00888.22 EAU82739.1 - 1.1e-184 615.5 15.4 1.1e-184 615.5 15.4 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EAU82739.1 - 4.4e-26 90.7 3.4 4.4e-26 90.7 3.4 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain MarR_2 PF12802.7 EAU82739.1 - 0.016 15.0 0.0 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 MarR family DUF1727 PF08353.10 EAU82739.1 - 0.06 13.3 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) Rrf2 PF02082.20 EAU82739.1 - 0.076 13.4 1.1 0.28 11.6 0.4 2.2 2 0 0 2 2 2 0 Transcriptional regulator Aldedh PF00171.22 EAU82741.1 - 3.7e-104 348.8 0.0 4.6e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.31 EAU82742.1 - 7e-11 42.3 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pro_isomerase PF00160.21 EAU82743.2 - 3.5e-39 134.6 0.0 5.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CDC45 PF02724.14 EAU82743.2 - 0.93 7.7 7.1 1.2 7.4 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nup188 PF10487.9 EAU82745.2 - 1e-31 109.7 0.0 6.2e-18 64.2 0.0 3.4 3 1 0 3 3 3 3 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EAU82745.2 - 1.3e-05 24.2 0.0 2.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup192 PF11894.8 EAU82745.2 - 0.00021 18.6 1.2 0.036 11.2 0.0 2.7 3 0 0 3 3 3 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 XPC-binding PF09280.11 EAU82745.2 - 0.0009 18.9 0.5 0.2 11.4 0.2 2.9 2 0 0 2 2 2 2 XPC-binding domain CSTF2_hinge PF14327.6 EAU82745.2 - 0.0059 17.0 2.4 12 6.4 0.1 4.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 MMR_HSR1 PF01926.23 EAU82746.2 - 5.5e-09 36.1 0.0 5.5e-09 36.1 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU82746.2 - 1.1e-08 34.7 0.0 1.1e-08 34.7 0.0 2.4 2 1 1 3 3 3 1 AIG1 family Dynamin_N PF00350.23 EAU82746.2 - 4.6e-06 26.8 5.0 0.001 19.1 1.7 4.2 2 2 1 3 3 2 2 Dynamin family Septin PF00735.18 EAU82746.2 - 0.00011 21.7 0.0 0.00011 21.7 0.0 2.2 2 1 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 EAU82746.2 - 0.00032 20.7 0.6 0.0014 18.5 0.6 2.1 1 0 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 EAU82746.2 - 0.0046 16.1 0.5 0.0046 16.1 0.5 2.2 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) GBP PF02263.19 EAU82746.2 - 0.0061 15.8 0.0 0.23 10.7 0.0 2.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain FeoB_N PF02421.18 EAU82746.2 - 0.0071 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.6 EAU82746.2 - 0.065 13.0 0.6 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAU82746.2 - 0.14 12.7 15.7 14 6.2 15.7 2.8 1 1 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 EAU82746.2 - 0.16 11.2 2.9 0.14 11.4 0.6 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Xan_ur_permease PF00860.20 EAU82748.2 - 1e-57 195.6 31.4 3.7e-56 190.5 31.4 2.1 1 1 0 1 1 1 1 Permease family HXXEE PF13787.6 EAU82748.2 - 0.14 13.0 0.1 0.14 13.0 0.1 3.7 4 1 1 5 5 5 0 Protein of unknown function with HXXEE motif IncD PF17628.2 EAU82748.2 - 2.3 8.0 9.5 0.16 11.8 2.2 2.6 3 0 0 3 3 3 0 Inclusion membrane protein D Hist_deacetyl PF00850.19 EAU82749.2 - 7.1e-82 275.3 0.1 1e-81 274.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 EAU82750.2 - 1.7e-11 44.0 0.0 5.4e-10 39.1 0.0 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU82750.2 - 0.00012 21.5 0.1 0.00067 19.0 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase 2OG-FeII_Oxy_2 PF13532.6 EAU82752.2 - 6.3e-10 39.6 0.0 8.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 4HBT PF03061.22 EAU82753.1 - 9.7e-09 35.5 0.1 1.7e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily PigN PF04987.14 EAU82755.2 - 1.2e-129 433.2 29.8 1.6e-129 432.8 29.8 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EAU82755.2 - 6.5e-09 35.8 0.3 1.3e-06 28.2 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EAU82755.2 - 4e-05 23.2 0.1 9.3e-05 22.0 0.1 1.7 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EAU82755.2 - 0.0057 16.0 0.0 0.0097 15.3 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Arrestin_N PF00339.29 EAU82756.2 - 1.4e-09 38.2 0.0 3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EAU82756.2 - 0.011 16.2 0.1 1.5 9.2 0.1 3.0 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain EVE PF01878.18 EAU82757.2 - 8.5e-42 142.6 0.0 1.9e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 EVE domain Paf1 PF03985.13 EAU82757.2 - 0.0071 15.4 2.0 0.013 14.5 2.0 1.4 1 0 0 1 1 1 1 Paf1 CRISPR_assoc PF08798.11 EAU82764.2 - 0.0067 16.5 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 2 CRISPR associated protein F-box-like PF12937.7 EAU82764.2 - 0.067 13.1 0.9 0.25 11.3 0.9 2.1 1 1 0 1 1 1 0 F-box-like Stevor PF17410.2 EAU82768.2 - 0.0026 17.3 0.1 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4381 PF14316.6 EAU82768.2 - 0.0083 16.4 1.2 0.016 15.4 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) MFS_1 PF07690.16 EAU82768.2 - 0.067 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily 7tm_3 PF00003.22 EAU82768.2 - 0.12 12.1 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR LPG_synthase_TM PF03706.13 EAU82768.2 - 0.15 11.5 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region TMIE PF16038.5 EAU82768.2 - 0.15 11.9 1.0 0.34 10.8 1.0 1.5 1 0 0 1 1 1 0 TMIE protein G-alpha PF00503.20 EAU82769.1 - 8.3e-114 380.4 0.0 9.8e-114 380.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU82769.1 - 2.4e-12 46.7 0.0 4e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 EAU82769.1 - 0.00017 21.1 0.1 0.00028 20.3 0.1 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 EAU82769.1 - 0.0026 18.0 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EAU82769.1 - 0.046 13.5 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EAU82769.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 EAU82771.2 - 4.9e-45 154.3 0.0 6.3e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Questin_oxidase PF14027.6 EAU82773.1 - 2.5e-86 290.3 0.1 2.9e-86 290.1 0.1 1.0 1 0 0 1 1 1 1 Questin oxidase-like Beta-lactamase PF00144.24 EAU82774.1 - 3e-44 151.6 0.0 4.1e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Pyr_redox_2 PF07992.14 EAU82775.2 - 5.6e-26 91.5 0.0 7.8e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU82775.2 - 8.3e-10 39.1 0.8 1.4e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU82775.2 - 0.00059 19.5 0.1 0.0019 17.8 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAU82775.2 - 0.06 12.6 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EAU82775.2 - 0.091 13.0 0.0 0.4 11.0 0.0 2.1 2 1 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 EAU82775.2 - 0.17 10.9 0.2 1.5 7.8 0.1 1.9 1 1 1 2 2 2 0 Lycopene cyclase protein 3Beta_HSD PF01073.19 EAU82776.1 - 1.2e-23 83.6 0.0 4.5e-09 35.7 0.0 3.3 3 0 0 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAU82776.1 - 8.8e-16 57.8 0.0 5.6e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EAU82776.1 - 1.1e-07 31.6 0.0 0.0048 16.4 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EAU82776.1 - 1.7e-05 24.9 0.0 0.00041 20.3 0.0 2.2 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAU82776.1 - 0.00051 19.5 0.0 0.069 12.5 0.0 2.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAU82776.1 - 0.0036 16.5 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EAU82776.1 - 0.14 11.6 0.0 0.65 9.4 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DUF3584 PF12128.8 EAU82778.2 - 0.74 7.2 30.1 1.4 6.4 30.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 EAU82778.2 - 9 6.7 36.6 93 3.4 35.2 2.3 1 1 1 2 2 2 0 Fez1 CorA PF01544.18 EAU82778.2 - 9.5 5.4 7.3 2.2 7.5 1.6 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein 3Beta_HSD PF01073.19 EAU82779.2 - 3.1e-20 72.3 0.0 3.4e-19 68.9 0.0 2.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAU82779.2 - 2.8e-07 30.0 0.0 4.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EAU82779.2 - 5.1e-06 26.1 0.0 2.2e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAU82779.2 - 0.0014 18.5 0.0 0.0072 16.2 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EAU82779.2 - 0.015 14.4 0.0 0.036 13.2 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AP_endonuc_2 PF01261.24 EAU82779.2 - 0.055 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel RmlD_sub_bind PF04321.17 EAU82779.2 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4616 PF15394.6 EAU82785.2 - 5.6e-05 22.3 0.0 0.00035 19.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4616) DUF5094 PF17015.5 EAU82785.2 - 2.1 8.4 7.2 21 5.2 6.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) DUF1258 PF06869.12 EAU82786.2 - 0.00088 18.8 0.0 0.002 17.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4218 PF13960.6 EAU82786.2 - 0.0035 17.0 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF953 PF06110.11 EAU82787.1 - 0.17 11.5 0.3 0.32 10.6 0.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Nucleo_P87 PF07267.11 EAU82787.1 - 0.34 9.7 1.5 0.4 9.5 1.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RVP_2 PF08284.11 EAU82797.2 - 0.032 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.23 EAU82797.2 - 0.61 10.3 8.5 0.74 10.0 1.5 2.4 2 0 0 2 2 2 0 Zinc knuckle Zn_Tnp_IS1595 PF12760.7 EAU82797.2 - 0.66 10.0 3.2 1.6 8.8 3.2 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.13 EAU82797.2 - 0.92 9.6 3.1 39 4.4 0.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-CCHC_4 PF14392.6 EAU82797.2 - 4 7.3 6.3 0.63 9.8 1.6 2.0 2 0 0 2 2 2 0 Zinc knuckle PCI PF01399.27 EAU82800.1 - 1.6e-06 28.6 0.0 2.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain HNH_2 PF13391.6 EAU82801.2 - 0.002 18.2 0.1 0.0049 17.0 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Podoplanin PF05808.11 EAU82802.1 - 0.025 14.7 0.0 0.025 14.7 0.0 2.3 3 0 0 3 3 3 0 Podoplanin SKG6 PF08693.10 EAU82802.1 - 0.036 13.5 4.3 0.077 12.4 4.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EAU82802.1 - 0.068 14.1 0.0 0.19 12.7 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmH PF03918.14 EAU82802.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein GDPD PF03009.17 EAU82804.2 - 1.3e-22 80.7 0.3 5.3e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EAU82804.2 - 0.00047 20.5 0.7 0.0012 19.2 0.7 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family AAA_12 PF13087.6 EAU82805.2 - 8.9e-43 146.2 0.0 1.5e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU82805.2 - 5.3e-22 78.9 0.0 1e-20 74.6 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU82805.2 - 0.00018 21.3 0.0 0.022 14.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAU82805.2 - 0.0014 19.0 0.0 0.0058 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EAU82805.2 - 0.0091 15.6 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EAU82805.2 - 0.079 12.8 0.2 0.27 11.1 0.2 1.9 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Dpy19 PF10034.9 EAU82807.1 - 0.22 9.7 0.1 0.31 9.2 0.1 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Pkinase PF00069.25 EAU82808.2 - 4.7e-69 232.7 0.0 5.8e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU82808.2 - 4.4e-32 111.4 0.0 6.1e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAU82808.2 - 0.00048 19.2 0.0 0.0007 18.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Ribosomal_S26e PF01283.19 EAU82809.2 - 3.5e-54 181.8 8.8 4.2e-54 181.6 8.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EAU82809.2 - 0.023 14.6 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc binding domain 3Beta_HSD PF01073.19 EAU82814.1 - 7.9e-27 94.0 0.0 4.5e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAU82814.1 - 2.2e-11 43.4 0.0 1.2e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EAU82814.1 - 4.6e-08 32.8 0.0 1.2e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAU82814.1 - 6.7e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EAU82814.1 - 3.7e-06 26.9 0.0 6.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EAU82814.1 - 0.00027 20.4 0.0 0.0013 18.3 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAU82814.1 - 0.009 15.2 0.0 0.019 14.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EAU82814.1 - 0.046 14.0 0.1 0.62 10.3 0.1 2.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EAU82814.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 EAU82815.1 - 7.8e-27 94.0 0.0 2.2e-26 92.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAU82815.1 - 1.5e-09 37.4 0.0 5.6e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EAU82815.1 - 2.7e-08 33.6 0.0 9.2e-08 31.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAU82815.1 - 0.00014 21.1 0.0 0.00047 19.4 0.0 1.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EAU82815.1 - 0.00017 21.6 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EAU82815.1 - 0.00023 21.1 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Pkinase_fungal PF17667.1 EAU82816.2 - 6.8e-15 54.8 0.0 3.6e-10 39.2 0.0 2.6 2 1 0 2 2 2 2 Fungal protein kinase Questin_oxidase PF14027.6 EAU82817.2 - 2.5e-76 257.4 0.0 2.9e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like Epimerase PF01370.21 EAU82818.1 - 9.3e-06 25.3 0.0 0.035 13.6 0.0 2.2 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EAU82818.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAU82818.1 - 0.0011 18.9 0.2 0.0027 17.6 0.2 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EAU82818.1 - 0.0014 17.9 0.0 0.0033 16.6 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 EAU82818.1 - 0.019 15.4 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EAU82818.1 - 0.047 14.3 0.0 0.23 12.1 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EAU82818.1 - 0.05 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain zf-PARP PF00645.18 EAU82819.1 - 5.2e-25 88.1 0.1 5.2e-25 88.1 0.1 2.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MFS_1 PF07690.16 EAU82820.1 - 1.1e-13 50.9 20.1 1.5e-13 50.4 20.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Hira PF07569.11 EAU82822.2 - 1.6e-35 122.9 0.0 2.9e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 EAU82822.2 - 7.8e-30 102.5 23.8 6.8e-07 29.9 0.3 8.1 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82822.2 - 1.4e-15 57.4 1.9 0.0025 18.1 0.0 6.1 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain zf-C2H2_jaz PF12171.8 EAU82823.2 - 4.7e-18 65.0 12.9 0.0038 17.5 0.0 6.4 5 1 1 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU82823.2 - 5.1e-13 48.9 12.2 0.00046 20.5 0.1 6.6 7 0 0 7 7 6 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EAU82823.2 - 1.8e-10 40.7 32.4 0.038 14.4 0.1 7.4 8 0 0 8 8 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU82823.2 - 2.8e-10 40.2 33.4 0.019 15.7 0.1 7.8 8 0 0 8 8 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAU82823.2 - 5e-06 26.4 15.8 0.0031 17.5 0.0 5.6 4 1 1 5 5 5 2 C2H2-type zinc finger zf-C3HC4 PF00097.25 EAU82823.2 - 0.00028 20.7 13.0 0.00028 20.7 13.0 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU82823.2 - 0.0022 17.9 13.3 0.0022 17.9 13.3 3.9 2 1 2 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAU82823.2 - 0.0049 16.7 12.6 0.0049 16.7 12.6 3.7 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU82823.2 - 0.0052 17.1 12.7 0.0052 17.1 12.7 4.2 3 1 1 4 4 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EAU82823.2 - 0.0076 16.1 11.3 0.0076 16.1 11.3 4.2 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_2 PF12756.7 EAU82823.2 - 0.034 14.5 20.7 4.1 7.8 0.1 5.8 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 EAU82823.2 - 0.081 13.6 9.7 5.7 7.6 3.5 3.7 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-RING_6 PF14835.6 EAU82823.2 - 0.15 12.0 8.6 0.4 10.6 8.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF951 PF06107.11 EAU82823.2 - 0.17 11.8 0.2 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-RING_UBOX PF13445.6 EAU82823.2 - 6.5 6.9 17.9 0.46 10.6 8.5 3.1 3 0 0 3 3 3 0 RING-type zinc-finger DUF4336 PF14234.6 EAU82824.2 - 3.1e-13 49.6 0.0 2.1e-07 30.4 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Big_1 PF02369.16 EAU82825.1 - 4.7 7.3 14.6 0.11 12.6 6.2 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) DUF647 PF04884.14 EAU82827.2 - 5.7e-79 265.1 3.6 9e-79 264.5 3.6 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Aldo_ket_red PF00248.21 EAU82827.2 - 1.1e-77 261.2 0.0 1.4e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PHtD_u1 PF16645.5 EAU82828.2 - 0.18 12.3 0.6 0.29 11.6 0.6 1.3 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein ABC_membrane_2 PF06472.15 EAU82829.1 - 4.1e-71 239.5 0.1 9.1e-71 238.4 0.0 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EAU82829.1 - 6.2e-18 65.6 0.0 1.3e-17 64.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAU82829.1 - 0.042 13.3 0.1 2.8 7.3 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 EAU82829.1 - 0.043 13.2 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_26 PF13500.6 EAU82829.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lentiviral_Tat PF02998.14 EAU82830.2 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Lentiviral Tat protein Mif2_N PF15624.6 EAU82830.2 - 0.79 10.4 3.3 1.4 9.7 3.3 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal IF4E PF01652.18 EAU82831.1 - 2.7e-54 183.3 0.0 3.9e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glyco_transf_8 PF01501.20 EAU82832.1 - 3.7e-24 85.7 0.0 7.8e-23 81.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.6 EAU82832.1 - 8.9e-18 65.3 0.0 2.3e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EAU82832.1 - 1.3e-06 27.8 0.0 2.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Glyco_transf_24 PF18404.1 EAU82832.1 - 3.8e-05 23.2 0.1 0.00027 20.5 0.1 2.0 1 1 0 1 1 1 1 Glucosyltransferase 24 DUF938 PF06080.12 EAU82832.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 EAU82832.1 - 0.23 11.2 0.0 0.46 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) F-box-like PF12937.7 EAU82834.2 - 1.4e-05 24.9 1.9 6.7e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU82834.2 - 7.8e-05 22.4 3.8 0.0003 20.6 0.0 3.0 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 EAU82834.2 - 0.068 13.1 0.9 0.29 11.0 0.1 2.0 2 0 0 2 2 2 0 F-box DUF4246 PF14033.6 EAU82835.2 - 1.6e-177 591.2 0.0 1.9e-177 590.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EAU82835.2 - 0.021 15.2 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CENP-T_C PF15511.6 EAU82836.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAU82836.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EAU82836.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EAU82836.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU82836.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAU82836.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C3HC4_3 PF13920.6 EAU82838.2 - 7.8e-06 25.6 4.0 1.3e-05 24.9 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU82838.2 - 0.00011 22.1 4.7 0.00018 21.4 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAU82838.2 - 0.0037 17.6 6.1 0.0068 16.7 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAU82838.2 - 0.0044 16.9 6.1 0.0079 16.0 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU82838.2 - 0.019 14.8 6.7 0.036 13.9 6.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RRM_1 PF00076.22 EAU82838.2 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.6 EAU82838.2 - 0.17 12.0 7.1 0.36 10.9 7.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAU82838.2 - 0.3 11.0 6.1 0.64 9.9 6.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3295 PF11702.8 EAU82839.1 - 0.067 12.5 0.8 0.093 12.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Toxin_10 PF05431.11 EAU82839.1 - 0.092 12.2 3.3 0.21 11.0 3.3 1.6 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 VP4_helical PF17478.2 EAU82839.1 - 0.1 12.0 2.5 0.18 11.2 1.8 1.6 2 0 0 2 2 2 0 Rotavirus VP4 helical domain CEL_III_C PF18054.1 EAU82839.1 - 3.3 7.8 8.5 1.2 9.1 5.5 1.9 2 0 0 2 2 2 0 CEL-III C-terminal CCDC106 PF15794.5 EAU82842.2 - 1.2 8.8 4.6 0.2 11.4 0.9 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 bZIP_1 PF00170.21 EAU82846.2 - 2.2e-05 24.5 8.9 8.4e-05 22.6 8.9 2.1 1 0 0 1 1 1 1 bZIP transcription factor LRR19-TM PF15176.6 EAU82846.2 - 0.45 10.5 2.4 1.5 8.8 2.4 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain WD40 PF00400.32 EAU82848.1 - 2.5e-14 53.4 15.2 0.00069 20.4 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU82848.1 - 2.9e-05 24.3 2.6 0.0032 17.7 0.3 3.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU82848.1 - 0.0013 17.8 0.0 1.9 7.4 0.1 3.8 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2486 PF10667.9 EAU82849.1 - 0.39 10.9 5.5 0.42 10.8 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) F-box-like PF12937.7 EAU82857.1 - 0.0088 15.9 0.2 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU82857.1 - 0.0091 15.9 0.1 0.032 14.1 0.1 1.8 2 0 0 2 2 2 1 F-box AAA_12 PF13087.6 EAU82858.2 - 7.1e-45 153.1 0.0 1.3e-44 152.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU82858.2 - 1.5e-24 87.2 0.0 1.2e-11 44.9 0.0 3.1 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 EAU82858.2 - 8.7e-12 45.2 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU82858.2 - 2.2e-09 37.8 0.0 1.2e-08 35.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EAU82858.2 - 0.00013 21.6 0.0 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EAU82858.2 - 0.00016 21.7 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EAU82858.2 - 0.0022 18.4 0.0 0.0073 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU82858.2 - 0.004 17.4 0.0 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EAU82858.2 - 0.006 16.1 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 EAU82858.2 - 0.0096 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 EAU82858.2 - 0.02 14.0 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein UvrD_C_2 PF13538.6 EAU82858.2 - 0.033 14.0 0.2 0.23 11.3 0.2 2.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EAU82858.2 - 0.035 13.4 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_10 PF13374.6 EAU82858.2 - 0.04 13.8 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA PF00004.29 EAU82858.2 - 0.045 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ASH PF15780.5 EAU82858.2 - 0.15 12.3 0.0 0.73 10.1 0.0 2.2 1 1 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CTP_synth_N PF06418.14 EAU82860.1 - 4.5e-121 403.2 0.2 5.8e-121 402.8 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EAU82860.1 - 3.1e-47 160.8 0.0 5.5e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAU82860.1 - 0.0064 16.3 0.0 0.049 13.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 EAU82860.1 - 0.056 13.5 0.0 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ELFV_dehydrog PF00208.21 EAU82861.1 - 7.6e-74 248.5 0.2 9.3e-74 248.2 0.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EAU82861.1 - 1.5e-50 170.4 0.0 2.9e-50 169.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain F-box PF00646.33 EAU82864.2 - 1.6e-07 31.0 2.3 3.2e-07 30.1 2.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU82864.2 - 7.1e-06 25.8 1.8 1.6e-05 24.7 1.8 1.6 1 0 0 1 1 1 1 F-box-like LepA_C PF06421.12 EAU82865.1 - 0.14 12.3 0.8 0.24 11.6 0.8 1.4 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus Pribosyltran PF00156.27 EAU82866.2 - 6.5e-17 61.5 0.3 8.8e-17 61.1 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C2H2 PF00096.26 EAU82867.1 - 0.0013 19.0 0.5 0.003 17.9 0.1 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EAU82867.1 - 0.21 12.2 0.6 0.49 11.1 0.6 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain AA_kinase PF00696.28 EAU82868.2 - 1.2e-36 126.6 0.0 1.6e-35 122.9 0.0 2.3 1 1 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EAU82868.2 - 7.9e-15 54.4 3.8 3.1e-12 46.1 0.6 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EAU82868.2 - 8.1e-12 44.7 1.1 5.6e-06 26.0 0.1 2.9 2 0 0 2 2 2 2 ACT domain F-box-like PF12937.7 EAU82869.1 - 2.6e-06 27.2 0.0 7.9e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU82869.1 - 6.2e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EAU82869.1 - 4.2 7.9 9.8 5.5 7.6 0.0 4.4 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) zf-H2C2_5 PF13909.6 EAU82870.1 - 2.2e-09 36.9 6.5 0.00027 20.6 0.3 4.4 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EAU82870.1 - 2.2e-08 34.1 10.0 0.00065 20.0 0.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU82870.1 - 2.6e-05 24.7 10.0 0.014 16.2 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU82870.1 - 0.0001 22.6 10.4 1 9.9 0.2 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 EAU82870.1 - 0.0041 17.4 5.3 0.0066 16.7 2.5 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 EAU82870.1 - 0.013 16.1 1.4 18 6.1 0.0 3.4 2 1 1 3 3 3 0 FOXP coiled-coil domain OrsD PF12013.8 EAU82870.1 - 0.02 15.4 2.5 0.38 11.2 0.4 2.9 2 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Vac_Fusion PF02346.16 EAU82872.1 - 0.022 14.4 2.7 0.052 13.2 0.3 2.8 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 T6SS_VasE PF05936.12 EAU82872.1 - 0.076 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE DUF1664 PF07889.12 EAU82872.1 - 0.65 10.0 6.1 0.5 10.4 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EAU82872.1 - 0.73 10.1 2.9 3.4 7.9 1.5 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Fib_alpha PF08702.10 EAU82872.1 - 0.84 9.8 7.9 2.8 8.1 4.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EAU82872.1 - 1.2 9.6 7.1 0.19 12.2 0.5 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 EAU82872.1 - 3.3 8.0 6.3 58 4.0 0.0 3.2 2 2 3 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF681 PF05080.12 EAU82873.1 - 0.2 12.3 0.0 0.44 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF681) WRNPLPNID PF15017.6 EAU82873.1 - 2.4 9.1 8.5 6.5 7.7 8.5 1.7 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box CxC2 PF18803.1 EAU82874.2 - 5.4e-22 78.0 0.1 1e-18 67.5 0.0 2.5 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 EAU82875.2 - 1.9e-05 24.2 0.0 0.00023 20.6 0.0 2.0 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily p450 PF00067.22 EAU82876.2 - 8.4e-72 242.4 0.0 1.3e-71 241.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Creatinase_N_2 PF16189.5 EAU82877.1 - 4.9e-53 179.5 0.1 9.1e-52 175.4 0.0 2.6 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EAU82877.1 - 9.5e-46 156.1 0.0 1.4e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EAU82877.1 - 2.9e-27 94.5 0.9 7.9e-27 93.1 0.3 2.2 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EAU82877.1 - 1.9e-24 86.8 0.0 9e-18 65.2 0.0 2.6 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Propep_M14 PF02244.16 EAU82877.1 - 0.037 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Oxysterol_BP PF01237.18 EAU82879.1 - 4.4e-45 154.1 0.1 3.6e-44 151.1 0.1 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein MIP PF00230.20 EAU82880.2 - 2.1e-44 151.9 5.2 4.6e-42 144.3 5.2 2.0 1 1 0 1 1 1 1 Major intrinsic protein AAA PF00004.29 EAU82882.2 - 5.1e-44 149.9 0.0 9.6e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU82882.2 - 1.4e-11 43.9 0.1 3.2e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EAU82882.2 - 2e-08 34.6 0.0 5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EAU82882.2 - 4.7e-07 29.7 0.7 1.1e-06 28.4 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EAU82882.2 - 2.2e-06 27.7 0.0 8.1e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU82882.2 - 7e-06 26.5 0.0 8.1e-05 23.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU82882.2 - 1.1e-05 25.8 0.5 0.0053 17.0 0.2 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EAU82882.2 - 5.6e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EAU82882.2 - 0.00046 20.7 0.4 0.017 15.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 EAU82882.2 - 0.00094 18.5 0.0 0.0022 17.3 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EAU82882.2 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAU82882.2 - 0.0022 17.8 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EAU82882.2 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EAU82882.2 - 0.0052 16.3 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EAU82882.2 - 0.0067 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAU82882.2 - 0.0093 16.2 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAU82882.2 - 0.012 15.4 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EAU82882.2 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EAU82882.2 - 0.016 14.5 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 EAU82882.2 - 0.019 14.7 0.0 0.098 12.4 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.13 EAU82882.2 - 0.024 13.8 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EAU82882.2 - 0.03 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EAU82882.2 - 0.03 14.3 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU82882.2 - 0.04 14.3 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 EAU82882.2 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EAU82882.2 - 0.07 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAU82882.2 - 0.071 13.4 0.1 0.42 10.9 0.0 2.2 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 EAU82882.2 - 0.099 11.9 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 EAU82882.2 - 0.11 13.0 0.0 0.37 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF5406 PF17400.2 EAU82882.2 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5406) AAA_11 PF13086.6 EAU82882.2 - 0.12 12.1 0.2 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAU82882.2 - 0.15 12.0 0.0 0.7 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain RdRP PF05183.12 EAU82883.2 - 2e-160 535.3 0.0 9e-160 533.1 0.0 1.9 2 0 0 2 2 2 1 RNA dependent RNA polymerase G-alpha PF00503.20 EAU82885.2 - 5.2e-141 469.9 0.0 6.3e-141 469.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU82885.2 - 2.3e-06 27.2 0.1 0.0039 16.7 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 EAU82885.2 - 0.00087 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 EAU82885.2 - 0.042 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_12 PF13087.6 EAU82886.2 - 8.2e-44 149.6 0.0 2.2e-43 148.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EAU82886.2 - 2.2e-31 109.6 0.1 2.2e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAU82886.2 - 4.3e-14 52.7 0.0 7.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU82886.2 - 1.6e-11 44.7 0.0 7.3e-11 42.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EAU82886.2 - 2.8e-07 30.4 0.0 0.00037 20.1 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain ResIII PF04851.15 EAU82886.2 - 6e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAU82886.2 - 0.0001 21.9 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.6 EAU82886.2 - 0.0023 18.3 0.0 0.0051 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.14 EAU82886.2 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Helicase DEAD PF00270.29 EAU82886.2 - 0.0053 16.5 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU82886.2 - 0.0078 16.5 0.0 0.076 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EAU82886.2 - 0.0088 15.8 0.0 10 5.8 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EAU82886.2 - 0.019 14.8 0.2 0.053 13.4 0.2 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 EAU82886.2 - 0.034 14.6 0.0 0.098 13.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EAU82886.2 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EAU82886.2 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 EAU82886.2 - 0.18 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 EAU82886.2 - 0.19 10.9 0.0 2.9 7.0 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase ERG4_ERG24 PF01222.17 EAU82887.2 - 3.8e-111 371.9 7.0 5e-111 371.5 6.7 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EAU82887.2 - 3.9e-05 23.3 0.5 0.0001 22.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EAU82887.2 - 0.0014 19.0 1.2 0.0014 19.0 1.2 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EAU82887.2 - 0.01 16.2 0.0 0.01 16.2 0.0 2.1 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NnrU PF07298.11 EAU82887.2 - 3.6 7.0 10.3 2.8 7.4 0.4 3.8 3 1 1 4 4 4 0 NnrU protein FAD_binding_4 PF01565.23 EAU82888.1 - 2.3e-24 85.7 0.4 4.5e-24 84.8 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU82888.1 - 1.2e-11 44.5 0.1 2.8e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Carboxyl_trans PF01039.22 EAU82889.2 - 5.9e-81 272.6 0.0 1.1e-80 271.7 0.0 1.3 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EAU82890.2 - 9.2e-55 185.4 0.0 1.4e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EAU82890.2 - 6.3e-23 80.9 0.0 5.2e-22 78.0 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EAU82890.2 - 8.2e-19 68.2 0.3 9.7e-17 61.5 0.1 2.3 1 1 1 2 2 2 2 Biotin carboxylase, N-terminal domain ATP-grasp PF02222.22 EAU82890.2 - 3e-08 33.4 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAU82890.2 - 6.6e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 EAU82890.2 - 3e-06 27.0 1.0 7.1e-06 25.8 1.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.6 EAU82890.2 - 0.015 14.9 0.0 0.1 12.2 0.0 2.1 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 EAU82890.2 - 0.061 12.9 0.1 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_3 PF02655.14 EAU82890.2 - 0.13 12.3 0.1 1.2 9.2 0.1 2.2 1 1 0 1 1 1 0 ATP-grasp domain FA_desaturase PF00487.24 EAU82891.1 - 7.6e-25 88.2 11.9 7.6e-25 88.2 11.9 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EAU82891.1 - 1e-18 66.5 0.6 1.9e-18 65.7 0.6 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HXXEE PF13787.6 EAU82891.1 - 3.1 8.6 7.3 0.31 11.9 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif HLH PF00010.26 EAU82892.1 - 8e-11 41.7 0.0 2.2e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.6 EAU82892.1 - 0.0087 16.3 3.0 0.0087 16.3 3.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4611) YL1 PF05764.13 EAU82892.1 - 0.0098 16.0 4.8 0.0098 16.0 4.8 2.3 2 0 0 2 2 2 1 YL1 nuclear protein Sigma70_ner PF04546.13 EAU82892.1 - 0.071 13.0 2.2 0.19 11.6 2.2 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 EAU82892.1 - 0.097 10.9 2.0 0.18 10.1 2.0 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 EAU82892.1 - 0.22 11.5 29.7 1.1 9.2 6.5 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AT_hook PF02178.19 EAU82892.1 - 0.44 10.6 7.7 1.9 8.7 7.7 2.2 1 0 0 1 1 1 0 AT hook motif DAO PF01266.24 EAU82893.1 - 1.4e-31 110.4 0.0 1.8e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU82893.1 - 0.03 13.6 0.0 0.085 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU82893.1 - 0.034 13.2 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Glu_dehyd_C PF16912.5 EAU82893.1 - 0.04 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_8 PF13450.6 EAU82893.1 - 0.053 13.8 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EAU82893.1 - 0.094 12.4 0.3 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EAU82893.1 - 0.16 12.6 0.6 0.46 11.1 0.6 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CBM_21 PF03370.13 EAU82894.1 - 1.5e-11 44.4 0.7 3.1e-11 43.4 0.7 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) Alpha-amylase PF00128.24 EAU82894.1 - 4.2e-11 43.0 0.0 8.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CDC45 PF02724.14 EAU82895.2 - 1.5 7.0 5.3 2.1 6.5 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.9 EAU82895.2 - 9 6.2 12.9 21 5.0 12.9 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DEAD PF00270.29 EAU82896.2 - 3.9e-39 134.2 0.2 8.7e-39 133.1 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU82896.2 - 1.6e-20 73.5 0.0 6.5e-18 65.1 0.0 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EAU82896.2 - 2.9e-05 24.1 0.0 5.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EAU82896.2 - 0.0032 16.3 0.2 0.053 12.3 0.1 2.5 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF3037 PF11236.8 EAU82896.2 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) ERCC3_RAD25_C PF16203.5 EAU82896.2 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase FAD_binding_4 PF01565.23 EAU82898.1 - 8.9e-24 83.8 0.8 1.6e-23 83.0 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU82898.1 - 1.3e-11 44.3 0.4 3.5e-11 43.0 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like DER1 PF04511.15 EAU82899.2 - 3.1e-13 50.1 4.6 3.4e-07 30.4 0.5 2.1 2 0 0 2 2 2 2 Der1-like family DER1 PF04511.15 EAU82900.1 - 2.4e-30 105.9 3.0 3e-30 105.6 3.0 1.0 1 0 0 1 1 1 1 Der1-like family Ycf4 PF02392.16 EAU82900.1 - 2.2 7.8 4.0 9.2 5.8 0.5 2.1 2 0 0 2 2 2 0 Ycf4 AAA_12 PF13087.6 EAU82902.2 - 2.3e-45 154.7 0.0 3.5e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU82902.2 - 3.5e-27 95.8 0.1 8.3e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EAU82902.2 - 3.5e-12 46.9 0.0 9.8e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU82902.2 - 7.1e-12 45.4 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EAU82902.2 - 2.8e-05 23.8 0.0 0.029 13.9 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EAU82902.2 - 0.00067 19.5 0.0 5.6 6.6 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EAU82902.2 - 0.0028 17.7 0.0 0.007 16.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAU82902.2 - 0.013 15.0 0.0 5.5 6.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Cwf_Cwc_15 PF04889.12 EAU82902.2 - 0.021 14.6 0.3 0.036 13.8 0.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein OrsD PF12013.8 EAU82902.2 - 0.021 15.3 1.2 3.1 8.3 0.4 2.5 1 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D AAA_22 PF13401.6 EAU82902.2 - 0.024 14.9 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.6 EAU82902.2 - 0.04 13.8 0.4 0.15 11.9 0.4 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 EAU82902.2 - 0.055 13.9 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EAU82902.2 - 0.064 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EAU82902.2 - 0.082 13.3 0.0 0.45 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EAU82902.2 - 0.09 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PreAtp-grasp PF18604.1 EAU82902.2 - 0.2 11.3 0.1 2.1 8.0 0.0 2.8 4 0 0 4 4 4 0 Pre ATP-grasp domain Phytase PF02333.15 EAU82906.2 - 2.1e-60 204.7 2.4 3.7e-60 203.9 0.2 2.0 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.13 EAU82906.2 - 1.8e-07 31.4 26.2 0.00011 22.5 13.1 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EAU82906.2 - 0.0069 16.4 10.0 0.0069 16.4 10.0 3.0 3 0 0 3 3 3 1 Tenascin EGF domain PQQ_3 PF13570.6 EAU82906.2 - 0.049 14.1 0.4 0.46 11.0 0.4 2.7 1 0 0 1 1 1 0 PQQ-like domain EGF PF00008.27 EAU82906.2 - 0.14 12.5 23.4 0.69 10.3 3.2 2.6 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 EAU82906.2 - 6.2 7.1 19.3 0.69 10.1 2.6 2.5 2 0 0 2 2 2 0 Laminin EGF domain PBP1_TM PF14812.6 EAU82907.2 - 9.6 6.7 11.4 0.15 12.4 0.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mg_trans_NIPA PF05653.14 EAU82908.2 - 2.2e-95 319.1 17.2 4.9e-95 318.0 17.2 1.5 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EAU82908.2 - 3 8.0 28.3 0.049 13.8 5.4 3.6 3 1 0 3 3 3 0 EamA-like transporter family Roughex PF06020.11 EAU82909.2 - 2.5 7.1 5.3 2.6 7.1 5.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein XPA_C PF05181.12 EAU82910.2 - 0.028 14.4 0.6 0.55 10.2 0.2 2.5 2 0 0 2 2 2 0 XPA protein C-terminus DUF2046 PF09755.9 EAU82911.1 - 1.9e-12 47.1 7.8 8.7e-12 44.9 5.6 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) TORC_N PF12884.7 EAU82911.1 - 0.036 14.8 0.2 0.17 12.7 0.2 2.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus CK2S PF15011.6 EAU82911.1 - 0.91 9.4 6.6 11 5.9 6.6 2.1 1 1 0 1 1 1 0 Casein Kinase 2 substrate Abhydrolase_1 PF00561.20 EAU82912.1 - 8.6e-17 61.6 0.0 1.3e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU82912.1 - 9.8e-11 42.7 0.0 2.1e-10 41.6 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU82912.1 - 2.1e-08 33.7 0.0 3.3e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 EAU82912.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ndr PF03096.14 EAU82912.1 - 0.022 13.5 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Thioesterase PF00975.20 EAU82912.1 - 0.042 13.9 0.1 1.9 8.5 0.1 2.4 1 1 1 2 2 2 0 Thioesterase domain DUF89 PF01937.19 EAU82914.2 - 7.2e-103 344.2 0.2 9.8e-103 343.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 WW PF00397.26 EAU82915.2 - 4.3e-09 36.3 6.2 1.1e-08 35.0 6.2 1.8 1 0 0 1 1 1 1 WW domain UNC-50 PF05216.13 EAU82916.2 - 1.3e-86 289.7 15.8 1.5e-86 289.6 15.8 1.0 1 0 0 1 1 1 1 UNC-50 family DUF1772 PF08592.11 EAU82916.2 - 0.0067 16.7 8.7 1.1 9.5 4.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Metallophos PF00149.28 EAU82917.1 - 7.3e-36 124.6 0.3 1.4e-35 123.6 0.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EAU82917.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) CorA PF01544.18 EAU82919.2 - 0.00084 18.7 1.8 0.8 9.0 0.4 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein LRR_4 PF12799.7 EAU82921.2 - 0.00025 21.3 3.2 0.86 10.1 0.0 4.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAU82921.2 - 0.0014 18.4 0.5 0.12 12.1 0.0 3.0 2 0 0 2 2 2 1 Leucine rich repeat Mpp10 PF04006.12 EAU82921.2 - 0.0086 14.6 5.0 0.012 14.1 5.0 1.1 1 0 0 1 1 1 1 Mpp10 protein NUDIX PF00293.28 EAU82922.2 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain IATP PF04568.12 EAU82926.1 - 0.76 10.2 2.9 1.4 9.4 2.9 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF2034 PF10356.9 EAU82927.1 - 1.9e-19 69.8 0.3 3.6e-18 65.6 0.3 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EAU82927.1 - 3e-05 24.0 0.0 6.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease G-alpha PF00503.20 EAU82928.2 - 5.9e-73 246.1 0.0 2.3e-36 125.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit AurF PF11583.8 EAU82928.2 - 0.1 11.8 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF Arf PF00025.21 EAU82928.2 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family LRR_4 PF12799.7 EAU82930.2 - 3.4e-06 27.3 0.4 5.3 7.6 0.2 5.5 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) PRANC PF09372.10 EAU82930.2 - 0.081 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 PRANC domain F-box-like PF12937.7 EAU82930.2 - 0.12 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 EAU82930.2 - 8.2 6.8 5.8 10 6.4 0.0 3.7 5 0 0 5 5 5 0 Leucine Rich repeat Glyco_hydro_10 PF00331.20 EAU82931.1 - 1.2e-105 353.2 0.0 1.4e-105 352.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GH114_assoc PF14741.6 EAU82931.1 - 0.076 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Ank_2 PF12796.7 EAU82932.2 - 1.1e-56 189.3 0.8 1.1e-14 54.8 0.1 6.8 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU82932.2 - 4.3e-44 148.3 8.9 1.2e-07 32.2 0.1 11.1 5 2 8 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 EAU82932.2 - 2.2e-40 135.4 7.0 0.00035 20.9 0.0 12.1 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.6 EAU82932.2 - 1.1e-37 123.7 8.5 0.00027 21.1 0.0 13.4 13 1 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 EAU82932.2 - 4e-37 125.8 11.7 1.3e-09 38.1 0.0 9.9 5 2 5 10 10 10 7 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU82932.2 - 2.8e-05 24.4 0.0 0.00058 20.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU82932.2 - 0.00013 21.9 0.1 0.00047 20.1 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU82932.2 - 0.0091 16.4 0.0 0.052 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 EAU82932.2 - 0.036 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.9 EAU82932.2 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 EAU82932.2 - 0.13 11.6 0.0 4.7 6.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein Ank_2 PF12796.7 EAU82933.1 - 4.3e-20 72.1 0.0 4e-10 40.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU82933.1 - 3.2e-18 65.6 0.2 3.8e-09 36.6 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU82933.1 - 2.6e-12 47.0 0.1 7.7e-05 23.2 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAU82933.1 - 6.7e-11 42.1 0.0 0.017 15.5 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EAU82933.1 - 5.8e-10 38.5 0.0 0.082 13.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Cyclin_N PF00134.23 EAU82933.1 - 0.17 11.6 0.0 0.5 10.1 0.0 1.7 1 1 1 2 2 2 0 Cyclin, N-terminal domain TPD52 PF04201.15 EAU82934.1 - 0.053 13.1 3.3 0.34 10.5 0.2 3.2 3 1 1 4 4 4 0 Tumour protein D52 family ATP19 PF11022.8 EAU82935.2 - 6e-17 61.8 0.0 1.5e-16 60.5 0.0 1.6 1 1 0 1 1 1 1 ATP synthase subunit K Mito_carr PF00153.27 EAU82936.2 - 3.6e-61 203.1 0.5 1.3e-21 76.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MgtC PF02308.16 EAU82937.1 - 0.0034 17.7 2.8 0.0082 16.5 2.8 1.6 1 0 0 1 1 1 1 MgtC family Ni_hydr_CYTB PF01292.20 EAU82937.1 - 0.21 11.1 6.0 0.13 11.9 3.3 1.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF4293 PF14126.6 EAU82937.1 - 0.4 10.9 3.9 0.96 9.7 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Ran-binding PF05508.11 EAU82940.2 - 0.2 10.6 0.1 0.38 9.7 0.1 1.3 1 0 0 1 1 1 0 RanGTP-binding protein Exo70 PF03081.15 EAU82941.2 - 4.6e-36 124.7 0.0 6.6e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DUF3377 PF11857.8 EAU82943.2 - 0.43 10.5 3.2 11 6.0 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Barttin PF15462.6 EAU82945.2 - 0.023 14.5 1.2 0.034 13.9 1.2 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) PS_Dcarbxylase PF02666.15 EAU82946.1 - 7.3e-38 130.1 0.0 1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EAU82946.1 - 2.4e-37 128.0 0.0 3.9e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase BTB PF00651.31 EAU82947.1 - 3.6e-07 30.4 0.0 5.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PilP PF04351.13 EAU82948.2 - 4.5 7.2 6.8 0.16 12.0 0.6 1.7 2 0 0 2 2 2 0 Pilus assembly protein, PilP LZ_Tnp_IS66 PF13007.7 EAU82948.2 - 7.6 7.4 20.6 1.2 10.0 4.4 4.8 4 1 1 5 5 5 0 Transposase C of IS166 homeodomain zf-MYND PF01753.18 EAU82949.2 - 3e-07 30.4 12.9 5.7e-07 29.5 12.9 1.5 1 0 0 1 1 1 1 MYND finger BTB PF00651.31 EAU82950.2 - 3e-11 43.5 0.1 9.5e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain RHH_1 PF01402.21 EAU82950.2 - 0.06 13.3 1.3 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Megourin PF17560.2 EAU82950.2 - 0.15 12.3 1.1 0.26 11.5 1.1 1.4 1 0 0 1 1 1 0 Aphid Megourins CBFD_NFYB_HMF PF00808.23 EAU82951.1 - 3.7e-28 97.6 0.7 6.2e-28 96.9 0.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU82951.1 - 5.1e-05 23.6 0.5 7.4e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAU82951.1 - 0.028 14.5 0.0 0.037 14.2 0.0 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EAU82951.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EAU82951.1 - 0.053 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PAN_3 PF08277.12 EAU82951.1 - 0.079 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain Peptidase_M36 PF02128.15 EAU82952.2 - 4.4e-82 276.2 0.0 2.6e-80 270.3 0.0 2.2 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) PepSY PF03413.19 EAU82952.2 - 0.03 14.9 0.1 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain FTP PF07504.13 EAU82952.2 - 0.064 13.1 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Barttin PF15462.6 EAU82954.2 - 0.055 13.2 1.0 0.08 12.7 1.0 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Peptidase_M36 PF02128.15 EAU82955.2 - 6.5e-107 357.9 1.1 9.1e-107 357.4 1.1 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EAU82955.2 - 0.00063 19.5 0.1 0.0019 18.0 0.0 1.8 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EAU82955.2 - 0.047 14.3 0.2 0.088 13.4 0.2 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain CPSF_A PF03178.15 EAU82960.1 - 2e-82 277.1 0.0 3.2e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 EAU82960.1 - 2.2e-18 66.2 0.0 3.4e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_M36 PF02128.15 EAU82961.1 - 7e-141 469.7 4.2 9.1e-141 469.3 4.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EAU82961.1 - 0.013 15.3 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Beta-lactamase PF00144.24 EAU82962.2 - 1.1e-06 28.1 0.0 2e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase YesK PF14150.6 EAU82963.1 - 3 8.1 10.1 9.5 6.5 2.0 2.9 3 0 0 3 3 3 0 YesK-like protein ATP_bind_1 PF03029.17 EAU82965.1 - 1.6e-77 260.6 0.0 1.9e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ter PF05472.11 EAU82965.1 - 0.2 10.6 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 DNA replication terminus site-binding protein (Ter protein) DUF4805 PF16063.5 EAU82966.2 - 0.014 14.7 0.9 0.02 14.2 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) AAA_28 PF13521.6 EAU82967.2 - 1.6e-22 80.5 0.0 1.9e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAU82967.2 - 2.4e-05 24.8 0.0 3.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EAU82967.2 - 2.6e-05 24.8 0.0 4.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU82967.2 - 0.00013 22.4 0.1 0.00027 21.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EAU82967.2 - 0.0039 17.4 0.2 0.0097 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EAU82967.2 - 0.0044 16.9 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase Cytidylate_kin PF02224.18 EAU82967.2 - 0.0052 16.6 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Rad17 PF03215.15 EAU82967.2 - 0.0054 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 EAU82967.2 - 0.0063 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 EAU82967.2 - 0.0096 16.4 0.0 0.015 15.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EAU82967.2 - 0.014 15.7 0.3 0.028 14.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EAU82967.2 - 0.03 14.7 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAU82967.2 - 0.032 14.3 0.0 0.037 14.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 EAU82967.2 - 0.042 13.5 0.2 0.15 11.7 0.2 1.9 1 1 0 1 1 1 0 Thymidylate kinase APS_kinase PF01583.20 EAU82967.2 - 0.048 13.6 0.1 0.078 12.9 0.1 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase BTAD PF03704.17 EAU82967.2 - 0.061 13.8 0.1 5.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Cytidylate_kin2 PF13189.6 EAU82967.2 - 0.085 13.0 0.1 0.14 12.2 0.1 1.5 1 1 0 1 1 1 0 Cytidylate kinase-like family ATPase_2 PF01637.18 EAU82967.2 - 0.088 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Guanylate_kin PF00625.21 EAU82967.2 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase PduV-EutP PF10662.9 EAU82967.2 - 0.12 12.1 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EAU82967.2 - 0.12 12.3 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 EAU82967.2 - 0.13 12.3 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EAU82967.2 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_PrkA PF08298.11 EAU82967.2 - 0.16 10.8 0.0 0.27 10.1 0.0 1.5 1 1 0 1 1 1 0 PrkA AAA domain RdRP PF05183.12 EAU82968.2 - 1.1e-70 239.0 0.0 1.3e-43 149.6 0.0 2.4 2 0 0 2 2 2 2 RNA dependent RNA polymerase AAA_12 PF13087.6 EAU82968.2 - 3.9e-41 140.9 0.0 7.7e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU82968.2 - 5.6e-08 32.9 2.4 0.017 14.9 0.1 3.4 1 1 2 3 3 3 2 AAA domain TFIIA PF03153.13 EAU82968.2 - 1.1 9.2 7.6 0.43 10.5 3.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CoA_transf_3 PF02515.17 EAU82969.2 - 1.7e-36 126.2 0.0 2.1e-32 112.7 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III WD40 PF00400.32 EAU82970.2 - 7.6e-08 32.9 6.1 0.13 13.2 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.11 EAU82970.2 - 1.8e-07 31.1 0.2 1.8e-07 31.1 0.2 3.1 1 1 1 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 EAU82970.2 - 0.0075 16.0 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EAU82970.2 - 0.043 14.4 0.1 0.092 13.3 0.1 1.5 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Prp18 PF02840.15 EAU82970.2 - 0.05 13.7 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain DUF2749 PF10907.8 EAU82971.2 - 0.18 12.0 1.2 0.88 9.8 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) TFIIIC_sub6 PF10419.9 EAU82972.1 - 2.1e-09 37.1 0.1 6.5e-07 29.1 0.0 2.3 1 1 1 2 2 2 2 TFIIIC subunit triple barrel domain SPATIAL PF15256.6 EAU82972.1 - 0.07 13.5 1.1 0.081 13.2 1.1 1.1 1 0 0 1 1 1 0 SPATIAL PS_Dcarbxylase PF02666.15 EAU82973.2 - 3.7e-37 127.8 0.0 5.5e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EAU82973.2 - 4.5e-35 120.7 0.0 7.6e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase TOM20_plant PF06552.12 EAU82973.2 - 0.04 13.6 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 RnfC_N PF13375.6 EAU82973.2 - 0.12 12.3 0.1 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain SET PF00856.28 EAU82974.2 - 5.2e-14 53.0 0.0 1.7e-13 51.3 0.0 1.9 1 1 0 1 1 1 1 SET domain PS_Dcarbxylase PF02666.15 EAU82975.1 - 1.9e-36 125.5 0.0 2.5e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EAU82975.1 - 3.5e-34 117.8 0.0 5.8e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 EAU82975.1 - 0.075 13.0 0.1 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain TOM20_plant PF06552.12 EAU82975.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 ESCRT-II PF05871.12 EAU82975.1 - 0.15 12.3 0.5 0.25 11.6 0.5 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit PSDC PF12588.8 EAU82976.1 - 9.5e-40 135.8 0.0 1.5e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EAU82976.1 - 8.4e-37 126.7 0.0 1.2e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EAU82978.1 - 1.4e-38 132.5 0.0 2e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EAU82978.1 - 2e-37 128.3 0.0 3.2e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 EAU82978.1 - 0.074 13.0 0.1 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 EAU82978.1 - 0.083 12.6 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 EAU82978.1 - 0.14 12.4 0.1 0.77 10.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M23 PS_Dcarbxylase PF02666.15 EAU82979.1 - 4.1e-38 131.0 0.0 7.1e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EAU82979.1 - 3e-37 127.7 0.0 6e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Peptidase_M23 PF01551.22 EAU82979.1 - 0.15 12.3 0.2 0.76 10.0 0.0 2.3 3 0 0 3 3 3 0 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 EAU82979.1 - 0.3 11.0 3.0 0.86 9.5 0.9 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like SNF2_N PF00176.23 EAU82980.1 - 0.25 10.0 1.9 0.92 8.2 0.8 1.9 1 1 1 2 2 2 0 SNF2 family N-terminal domain SNF2_N PF00176.23 EAU82981.2 - 9.3e-34 116.7 0.5 1.5e-33 116.0 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU82981.2 - 1.9e-12 47.5 0.1 6e-12 45.9 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EAU82981.2 - 4.8e-08 32.7 7.7 9.5e-08 31.8 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU82981.2 - 2.5e-06 27.2 5.1 4.9e-06 26.3 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU82981.2 - 8.7e-06 25.5 9.3 2.7e-05 23.9 9.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU82981.2 - 2.4e-05 24.2 6.6 5.5e-05 23.0 6.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAU82981.2 - 4.6e-05 23.7 6.9 0.0001 22.6 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU82981.2 - 6.9e-05 22.8 1.5 0.00011 22.1 0.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-4CXXC_R1 PF10497.9 EAU82981.2 - 0.0023 18.1 1.4 0.0053 17.0 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_6 PF14835.6 EAU82981.2 - 0.058 13.3 1.2 0.15 12.0 1.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EAU82981.2 - 0.071 13.3 6.8 0.18 12.0 6.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EAU82981.2 - 0.071 12.9 6.8 0.16 11.8 6.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EAU82981.2 - 0.13 12.6 5.9 0.4 11.0 5.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAU82981.2 - 0.2 11.4 7.7 0.6 9.9 7.7 1.9 1 0 0 1 1 1 0 RING-like zinc finger CDC45 PF02724.14 EAU82981.2 - 0.24 9.7 17.6 0.13 10.5 11.9 2.3 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 EAU82981.2 - 0.45 8.6 20.3 0.78 7.8 20.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EAU82981.2 - 0.67 9.2 24.1 0.025 14.0 15.6 2.2 2 0 0 2 2 2 0 BUD22 Prok-RING_4 PF14447.6 EAU82981.2 - 0.94 9.4 7.2 4 7.4 7.2 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_Tnp_IS91 PF14319.6 EAU82981.2 - 3.9 7.6 6.3 2.1 8.4 1.8 2.6 1 1 1 2 2 2 0 Transposase zinc-binding domain SPT6_acidic PF14632.6 EAU82981.2 - 7.1 7.3 49.5 1.6 9.4 1.1 4.6 3 1 1 4 4 4 0 Acidic N-terminal SPT6 FA_desaturase PF00487.24 EAU82982.2 - 8e-17 61.9 16.6 1.4e-09 38.2 6.1 2.5 2 1 0 2 2 2 2 Fatty acid desaturase DUF3474 PF11960.8 EAU82982.2 - 1.3e-05 25.5 0.0 2.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Sec63 PF02889.16 EAU82983.1 - 6.9e-159 526.8 0.0 3.1e-87 292.0 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EAU82983.1 - 3e-36 124.8 1.5 1.2e-16 61.0 0.2 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EAU82983.1 - 2e-17 63.7 0.1 3e-08 33.9 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAU82983.1 - 4.1e-14 52.9 0.0 1.2e-08 35.3 0.0 4.7 4 2 0 4 4 4 2 Helicase conserved C-terminal domain PhoH PF02562.16 EAU82983.1 - 0.0025 17.3 0.0 0.006 16.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Peptidase_C39 PF03412.15 EAU82983.1 - 0.0093 15.8 0.0 0.6 9.9 0.0 2.9 2 0 0 2 2 2 1 Peptidase C39 family T2SSE PF00437.20 EAU82983.1 - 0.088 11.8 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_PWI PF18149.1 EAU82984.1 - 7.6e-34 116.2 0.0 2.4e-33 114.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain DUF4661 PF15576.6 EAU82984.1 - 2 8.2 4.7 0.31 10.9 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) UDG PF03167.19 EAU82985.2 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF1056 PF06341.11 EAU82987.2 - 6.4 7.2 8.9 12 6.3 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) Fer2_3 PF13085.6 EAU82988.1 - 1.1e-33 115.4 0.1 1.8e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EAU82988.1 - 2.6e-10 40.7 8.0 2.6e-10 40.7 8.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAU82988.1 - 3.3e-07 30.3 4.1 3.3e-07 30.3 4.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EAU82988.1 - 4.7e-07 30.2 9.4 4.7e-07 30.2 9.4 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EAU82988.1 - 0.0011 19.5 6.7 0.0011 19.5 6.7 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EAU82988.1 - 0.004 17.1 0.4 0.004 17.1 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EAU82988.1 - 0.4 10.9 5.5 0.86 9.8 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAU82988.1 - 4 8.5 13.4 0.9 10.5 8.5 2.4 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain F-box-like PF12937.7 EAU82989.1 - 6.3e-06 26.0 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like PAP2 PF01569.21 EAU82992.1 - 5.7e-18 65.0 10.3 5.7e-18 65.0 10.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily DUF1614 PF07758.11 EAU82992.1 - 0.034 14.2 0.3 1.7 8.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1614) PAP2_3 PF14378.6 EAU82992.1 - 7.5 6.2 19.6 7.6 6.2 15.1 3.1 2 1 0 2 2 2 0 PAP2 superfamily DUF2204 PF09970.9 EAU82993.1 - 0.018 14.7 0.0 0.045 13.4 0.0 1.6 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) AbiEii PF08843.11 EAU82993.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF1282 PF06930.12 EAU82999.2 - 0.0061 16.4 0.6 0.0099 15.7 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF3306 PF11748.8 EAU83000.2 - 0.023 15.5 4.0 0.023 15.5 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3306) MGC-24 PF05283.11 EAU83000.2 - 5.8 7.4 5.7 29 5.1 0.7 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CorA PF01544.18 EAU83001.2 - 0.007 15.7 1.7 0.016 14.5 1.7 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF5343 PF17278.2 EAU83001.2 - 0.081 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5343) CorA PF01544.18 EAU83003.1 - 0.012 15.0 2.7 0.025 13.9 2.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 EAU83003.1 - 0.025 14.6 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CPBP PF02517.16 EAU83003.1 - 0.12 12.7 2.1 0.35 11.3 2.0 1.6 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease RAB3GAP2_N PF14655.6 EAU83004.1 - 0.21 10.8 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus UPF0203 PF05254.12 EAU83005.1 - 3.3e-26 91.3 1.3 4e-26 91.0 1.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Methyltrn_RNA_2 PF04013.12 EAU83005.1 - 0.025 14.3 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase UCR_hinge PF02320.16 EAU83005.1 - 0.094 12.9 2.0 2.7 8.3 0.5 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein p450 PF00067.22 EAU83008.2 - 1.7e-63 215.0 0.0 4.2e-63 213.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_11 PF00457.17 EAU83009.1 - 4e-69 231.8 11.2 4e-69 231.8 11.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 EAU83009.1 - 3.5e-13 49.3 14.3 3.5e-13 49.3 14.3 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAU83009.1 - 0.013 15.7 2.7 0.025 14.8 2.7 1.5 1 0 0 1 1 1 0 Toxin 7 CFEM PF05730.11 EAU83012.1 - 0.027 14.6 5.3 0.032 14.3 5.3 1.1 1 0 0 1 1 1 0 CFEM domain Peptidase_M43 PF05572.13 EAU83013.1 - 2.4e-17 63.2 0.0 5.7e-17 62.0 0.0 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU83013.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU83013.1 - 0.0004 20.9 0.0 0.00068 20.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU83013.1 - 0.0037 16.9 0.2 0.011 15.4 0.0 1.8 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU83013.1 - 0.0096 15.8 0.2 0.027 14.3 0.2 1.7 1 1 0 1 1 1 1 Matrixin DUF4953 PF16313.5 EAU83013.1 - 0.057 12.6 0.0 0.11 11.7 0.0 1.4 2 0 0 2 2 2 0 Met-zincin Peptidase_M57 PF12388.8 EAU83013.1 - 0.098 12.3 1.8 0.48 10.0 1.8 2.0 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 EAU83013.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 EAU83013.1 - 0.17 11.4 0.5 0.34 10.5 0.5 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M66 PF10462.9 EAU83013.1 - 0.18 10.8 0.6 0.29 10.0 0.6 1.3 1 0 0 1 1 1 0 Peptidase M66 DHHC PF01529.20 EAU83014.2 - 4.1 7.5 11.2 2.2 8.4 0.6 2.7 2 1 1 3 3 3 0 DHHC palmitoyltransferase zf-MYND PF01753.18 EAU83015.1 - 7.3e-11 42.0 7.3 1.4e-10 41.0 7.3 1.5 1 0 0 1 1 1 1 MYND finger CorA PF01544.18 EAU83018.2 - 0.00036 19.9 0.2 0.00056 19.3 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 EAU83018.2 - 0.013 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4271 PF14093.6 EAU83018.2 - 0.11 12.4 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) FtsX PF02687.21 EAU83018.2 - 0.24 11.9 1.1 0.45 11.0 1.1 1.4 1 0 0 1 1 1 0 FtsX-like permease family Abhydrolase_9_N PF15420.6 EAU83019.1 - 0.0015 18.6 0.5 0.0024 17.9 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus DUF373 PF04123.13 EAU83019.1 - 5.7 6.3 12.2 1.1 8.6 7.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Ribosomal_L14e PF01929.17 EAU83020.2 - 1.3e-30 105.7 1.4 1.3e-30 105.7 0.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 EAU83020.2 - 0.00021 21.1 0.3 0.00043 20.1 0.3 1.5 1 0 0 1 1 1 1 KOW motif ATP_bind_2 PF03668.15 EAU83021.2 - 1e-09 38.1 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family Ndc1_Nup PF09531.10 EAU83021.2 - 0.041 12.6 5.3 0.043 12.5 5.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mago-bind PF09282.10 EAU83021.2 - 0.063 13.2 1.6 0.12 12.3 1.6 1.4 1 0 0 1 1 1 0 Mago binding Apt1 PF10351.9 EAU83021.2 - 0.093 11.6 2.8 0.08 11.8 2.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EAU83021.2 - 0.31 10.2 12.4 0.35 10.0 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 EAU83021.2 - 0.82 8.2 4.6 0.91 8.0 4.6 1.1 1 0 0 1 1 1 0 Macoilin family RsbRD_N PF14361.6 EAU83023.1 - 0.11 13.2 0.4 0.34 11.6 0.1 2.0 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF5500 PF17604.2 EAU83023.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5500) tRNA-synt_1 PF00133.22 EAU83024.2 - 0.18 10.0 0.0 0.24 9.6 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) DUF5336 PF17270.2 EAU83026.2 - 0.077 12.6 1.4 0.21 11.2 1.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5336) HPP PF04982.13 EAU83028.1 - 2.7e-43 147.0 5.8 4.8e-43 146.2 5.8 1.4 1 0 0 1 1 1 1 HPP family Neur_chan_memb PF02932.16 EAU83028.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Auts2 PF15336.6 EAU83028.1 - 0.4 10.8 2.8 0.68 10.0 2.8 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein zf-MYND PF01753.18 EAU83029.2 - 1.6e-09 37.7 1.5 3.4e-09 36.6 1.5 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 EAU83031.2 - 5e-10 39.3 8.4 1.1e-09 38.3 8.4 1.6 1 0 0 1 1 1 1 MYND finger DUF3849 PF12960.7 EAU83031.2 - 0.012 15.6 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) RseC_MucC PF04246.12 EAU83032.2 - 0.16 11.9 0.2 0.16 11.9 0.2 2.4 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC RNA_lig_T4_1 PF09511.10 EAU83033.1 - 4.4e-85 285.0 0.0 7.8e-85 284.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EAU83033.1 - 4.6e-23 82.2 0.0 3.4e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EAU83033.1 - 1.2e-07 31.5 0.0 4.1e-06 26.4 0.0 2.7 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain Pantoate_ligase PF02569.15 EAU83034.2 - 0.044 13.0 0.1 0.063 12.5 0.1 1.2 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase DUF5381 PF17353.2 EAU83034.2 - 7.5 6.3 11.9 0.052 13.3 1.6 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5381) Peroxidase_2 PF01328.17 EAU83038.2 - 3.5e-46 158.1 0.0 4.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 TPD PF14811.6 EAU83038.2 - 0.098 12.5 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif zf-MYND PF01753.18 EAU83041.2 - 7.8e-18 64.3 39.1 8.6e-11 41.7 9.9 2.9 3 0 0 3 3 3 2 MYND finger Ecl1 PF12855.7 EAU83041.2 - 0.099 13.8 10.9 2.4 9.3 3.4 2.6 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 EAU83041.2 - 3.6 8.0 16.4 5.6 7.4 4.7 2.6 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding HPP PF04982.13 EAU83042.2 - 1.1e-41 141.8 7.1 3.5e-41 140.2 6.4 1.9 2 0 0 2 2 2 1 HPP family ABC_trans_CmpB PF06541.11 EAU83042.2 - 0.0045 17.2 1.7 0.01 16.0 1.8 1.6 1 1 0 1 1 1 1 Putative ABC-transporter type IV FecCD PF01032.18 EAU83042.2 - 0.0087 15.1 4.5 0.064 12.3 3.5 2.0 2 0 0 2 2 2 1 FecCD transport family Transgly_assoc PF04226.13 EAU83042.2 - 0.13 12.5 7.1 0.58 10.5 0.2 3.2 3 0 0 3 3 3 0 Transglycosylase associated protein Acyl_transf_3 PF01757.22 EAU83042.2 - 0.53 9.3 8.5 0.13 11.3 3.9 1.8 1 1 1 2 2 2 0 Acyltransferase family DUF3792 PF12670.7 EAU83042.2 - 0.83 9.8 7.6 0.24 11.6 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) zf-MYND PF01753.18 EAU83043.1 - 4.2e-07 29.9 18.7 1.4e-06 28.2 18.7 1.9 1 1 0 1 1 1 1 MYND finger Peroxidase_2 PF01328.17 EAU83044.1 - 2.8e-48 164.9 0.0 3.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 TPD PF14811.6 EAU83044.1 - 0.12 12.3 0.4 0.21 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif DUF2183 PF09949.9 EAU83045.2 - 6.7e-25 87.3 0.0 1.4e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EAU83045.2 - 0.061 12.8 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF2561 PF10812.8 EAU83047.2 - 0.36 10.8 4.3 0.78 9.7 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) ANAPC4_WD40 PF12894.7 EAU83049.2 - 3.3e-05 24.1 0.0 0.14 12.4 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU83049.2 - 4.9e-05 24.0 0.0 0.21 12.5 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat CD52 PF15116.6 EAU83049.2 - 8.2 6.6 9.5 7 6.8 6.4 2.6 2 0 0 2 2 2 0 CAMPATH-1 antigen zf-C2H2_jaz PF12171.8 EAU83051.1 - 0.0006 20.0 0.2 0.001 19.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU83051.1 - 0.0032 17.8 0.6 0.0055 17.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAU83051.1 - 0.091 13.1 0.3 0.19 12.1 0.2 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 EAU83051.1 - 0.72 10.3 7.5 0.19 12.2 3.8 2.0 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Citrate_synt PF00285.21 EAU83052.2 - 4.4e-68 230.0 0.0 5.3e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Prp18 PF02840.15 EAU83053.1 - 3.1e-62 208.9 0.2 3.1e-62 208.9 0.2 2.6 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 EAU83053.1 - 5.8e-12 44.9 5.3 1.8e-11 43.4 5.3 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like COX6B PF02297.17 EAU83054.2 - 8.3e-19 67.6 10.2 9.7e-19 67.4 10.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EAU83054.2 - 0.55 10.3 5.1 0.93 9.6 5.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Oxidored_molyb PF00174.19 EAU83055.2 - 2.6e-58 196.4 0.0 4.1e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EAU83055.2 - 3.3e-18 66.0 1.1 9e-18 64.6 0.5 1.9 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain DUF1748 PF08520.10 EAU83056.2 - 2.9e-25 87.9 0.0 3.3e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) zf-Tim10_DDP PF02953.15 EAU83058.2 - 5.7e-09 35.5 2.1 5.7e-09 35.5 2.1 2.3 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DnaJ PF00226.31 EAU83059.2 - 3e-24 84.9 2.8 9.8e-24 83.3 2.3 2.1 2 0 0 2 2 2 1 DnaJ domain Mei5_like PF17021.5 EAU83059.2 - 0.012 15.7 0.1 0.037 14.1 0.1 1.8 1 0 0 1 1 1 0 Putative double-strand recombination repair-like ROS_MUCR PF05443.11 EAU83059.2 - 4.6 7.3 6.4 0.42 10.7 0.3 2.4 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein Cyt-b5 PF00173.28 EAU83062.1 - 3.8e-18 65.4 0.0 5.5e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ApoL PF05461.11 EAU83063.2 - 0.013 14.9 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein L CRAL_TRIO PF00650.20 EAU83065.1 - 6.3e-26 91.0 0.0 1.1e-25 90.2 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAU83065.1 - 6.2e-20 71.1 1.5 1.3e-19 70.1 1.5 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF4366 PF14283.6 EAU83065.1 - 0.083 12.9 1.2 0.25 11.4 1.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Fungal_trans PF04082.18 EAU83066.2 - 6e-20 71.4 0.2 9.5e-11 41.2 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Dynamitin PF04912.14 EAU83066.2 - 0.02 14.2 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Dynamitin Zn_clus PF00172.18 EAU83066.2 - 1.4 9.1 7.4 3.1 8.0 7.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MMR_HSR1 PF01926.23 EAU83067.2 - 2.1e-07 31.0 0.2 2.1e-07 31.0 0.2 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU83067.2 - 1.9e-06 27.4 0.1 1.9e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 AIG1 family Septin PF00735.18 EAU83067.2 - 0.00015 21.2 0.0 0.00015 21.2 0.0 2.0 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 EAU83067.2 - 0.00076 19.0 2.0 0.0013 18.3 0.0 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAU83067.2 - 0.00093 19.3 14.8 0.01 15.9 0.1 3.7 2 2 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EAU83067.2 - 0.0044 16.9 0.4 0.0044 16.9 0.4 2.3 2 1 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EAU83067.2 - 0.0061 15.7 0.5 0.018 14.1 0.5 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein IIGP PF05049.13 EAU83067.2 - 0.018 14.1 0.0 0.018 14.1 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EAU83067.2 - 0.028 14.2 1.0 0.037 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAU83067.2 - 0.04 14.2 4.5 0.21 11.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EAU83067.2 - 0.041 13.2 0.1 0.041 13.2 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EAU83067.2 - 0.15 12.5 0.1 0.15 12.5 0.1 2.6 2 1 0 2 2 1 0 ABC transporter AAA_29 PF13555.6 EAU83067.2 - 0.18 11.6 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 EAU83067.2 - 0.46 9.6 6.3 1.1 8.4 0.1 2.6 3 0 0 3 3 3 0 G-protein alpha subunit zf-C4H2 PF10146.9 EAU83067.2 - 0.51 10.6 13.4 0.99 9.7 13.4 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein RR_TM4-6 PF06459.12 EAU83067.2 - 0.55 10.0 10.2 0.97 9.2 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 EAU83067.2 - 0.8 7.8 12.7 1.2 7.3 12.7 1.1 1 0 0 1 1 1 0 Hsp70 protein V_ATPase_I PF01496.19 EAU83067.2 - 0.82 7.5 10.3 1.1 7.1 10.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NB-ARC PF00931.22 EAU83067.2 - 0.82 8.8 4.4 0.62 9.2 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain Cupin_8 PF13621.6 EAU83067.2 - 1.1 9.0 3.5 1.6 8.4 3.5 1.2 1 0 0 1 1 1 0 Cupin-like domain YlqD PF11068.8 EAU83067.2 - 1.3 9.3 27.2 1.4 9.3 11.5 2.2 1 1 1 2 2 2 0 YlqD protein Syntaxin_2 PF14523.6 EAU83067.2 - 1.6 9.1 13.4 0.83 10.1 8.6 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Fez1 PF06818.15 EAU83067.2 - 1.7 9.0 24.7 3 8.3 24.7 1.3 1 0 0 1 1 1 0 Fez1 Prominin PF05478.11 EAU83067.2 - 3.6 5.4 8.8 5.2 4.9 8.8 1.1 1 0 0 1 1 1 0 Prominin DnaJ_C PF01556.18 EAU83068.2 - 3.6e-18 66.1 0.0 5.2e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain F-box-like PF12937.7 EAU83069.1 - 2.2e-07 30.6 0.4 4.7e-05 23.2 0.2 2.5 2 0 0 2 2 2 2 F-box-like LIN37 PF15306.6 EAU83069.1 - 0.039 14.2 0.2 0.069 13.4 0.2 1.3 1 0 0 1 1 1 0 LIN37 UbiA PF01040.18 EAU83070.2 - 5.3e-58 196.3 20.2 5.3e-58 196.3 20.2 1.4 2 0 0 2 2 2 1 UbiA prenyltransferase family U1snRNP70_N PF12220.8 EAU83071.1 - 2.3e-27 95.5 4.7 3.4e-27 94.9 4.7 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EAU83071.1 - 1.2e-18 66.6 0.0 2.1e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeodomain PF00046.29 EAU83072.2 - 3.7e-17 61.9 3.2 7.8e-17 60.9 3.2 1.6 1 0 0 1 1 1 1 Homeodomain LRR_4 PF12799.7 EAU83074.2 - 0.3 11.6 2.7 16 6.1 0.4 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) TEA PF01285.18 EAU83076.1 - 4.5e-21 74.7 0.0 1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Zip PF02535.22 EAU83077.2 - 5.6e-42 144.1 10.7 1.3e-41 142.9 10.7 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Peptidase_C15 PF01470.17 EAU83078.2 - 1e-19 71.5 0.0 5.2e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 Pyroglutamyl peptidase HD PF01966.22 EAU83079.1 - 6.6e-07 29.6 0.2 1.4e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 HD domain DNA_pol3_delta2 PF13177.6 EAU83080.2 - 9.9e-14 51.4 0.2 3.2e-13 49.8 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EAU83080.2 - 2.9e-06 27.7 0.7 6.2e-06 26.7 0.7 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EAU83080.2 - 4.2e-06 26.6 0.2 6.7e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EAU83080.2 - 0.0068 16.8 0.1 0.027 14.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Rep_fac_C PF08542.11 EAU83080.2 - 0.01 16.2 0.2 0.032 14.6 0.0 1.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain AAA_5 PF07728.14 EAU83080.2 - 0.024 14.6 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PRK PF00485.18 EAU83080.2 - 0.035 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EAU83080.2 - 0.041 14.1 1.0 0.38 11.0 1.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAU83080.2 - 0.069 12.9 0.3 0.15 11.8 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAU83080.2 - 0.095 12.9 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Alk_phosphatase PF00245.20 EAU83081.2 - 1.4e-68 231.8 0.1 3.1e-68 230.6 0.1 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EAU83081.2 - 3.7e-06 26.6 0.2 1.1e-05 25.0 0.2 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EAU83081.2 - 0.0001 22.1 0.4 0.00023 20.9 0.1 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EAU83081.2 - 0.0098 14.5 0.2 0.015 14.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EAU83081.2 - 0.012 14.9 0.6 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 Metalloenzyme superfamily Flavi_M PF01004.19 EAU83081.2 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M Bud13 PF09736.9 EAU83082.2 - 1.3e-54 184.5 11.0 1.3e-54 184.5 11.0 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex KLRAQ PF10205.9 EAU83083.2 - 0.055 13.7 0.1 0.099 12.9 0.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein EMP70 PF02990.16 EAU83083.2 - 0.082 11.6 1.8 0.13 10.8 1.8 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 CorA PF01544.18 EAU83083.2 - 0.17 11.2 6.2 1.2 8.4 2.3 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Sigma54_AID PF00309.20 EAU83083.2 - 0.79 9.6 2.8 2.5 8.0 2.8 1.8 1 1 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) MFS_1 PF07690.16 EAU83084.2 - 3.1e-13 49.4 21.2 3.1e-13 49.4 21.2 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2407_C PF13373.6 EAU83084.2 - 0.22 11.7 0.0 8 6.6 0.1 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain Fungal_trans PF04082.18 EAU83086.2 - 4.7e-24 84.9 0.1 2.4e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU83086.2 - 2.4e-08 34.0 9.3 4.2e-08 33.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COQ9 PF08511.11 EAU83087.2 - 6.6e-12 45.0 0.1 2.1e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 COQ9 eIF3_subunit PF08597.10 EAU83088.1 - 1.2e-59 202.2 20.5 1.4e-59 202.0 20.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PHC2_SAM_assoc PF16616.5 EAU83088.1 - 0.21 12.4 4.5 12 6.8 0.5 2.8 2 1 1 3 3 3 0 Unstructured region on Polyhomeotic-like protein 1 and 2 HLH PF00010.26 EAU83089.1 - 8.3e-06 25.7 0.0 3.9e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain F-box-like PF12937.7 EAU83091.1 - 3.2e-09 36.5 0.1 0.0017 18.2 0.0 2.7 2 0 0 2 2 2 2 F-box-like Cu_amine_oxid PF01179.20 EAU83093.2 - 8.6e-129 430.0 8.2 1.4e-128 429.3 8.2 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EAU83093.2 - 1.2e-26 92.3 0.1 2.6e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EAU83093.2 - 0.00084 19.5 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Fungal_trans PF04082.18 EAU83094.2 - 8.8e-29 100.3 0.0 1.5e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU83094.2 - 5.4e-06 26.4 12.3 9.8e-06 25.6 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamitin PF04912.14 EAU83094.2 - 0.044 13.1 0.8 0.065 12.6 0.8 1.2 1 0 0 1 1 1 0 Dynamitin Whi5 PF08528.11 EAU83097.2 - 6.3e-05 22.5 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Whi5 like HIT PF01230.23 EAU83098.1 - 4.4e-24 85.1 0.2 6e-24 84.6 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EAU83098.1 - 9e-12 45.5 0.2 1.3e-11 45.0 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EAU83098.1 - 1.4e-05 24.9 0.7 2.4e-05 24.2 0.7 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Enterotoxin_HS1 PF08090.11 EAU83098.1 - 0.083 12.9 0.4 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 DUF1161 PF06649.12 EAU83098.1 - 0.099 12.9 0.1 4.2 7.6 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1161) SUR7 PF06687.12 EAU83099.2 - 0.015 14.9 0.6 0.017 14.8 0.6 1.1 1 0 0 1 1 1 0 SUR7/PalI family Metallophos PF00149.28 EAU83101.1 - 2.5e-10 41.2 0.8 1.4e-09 38.7 0.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 EAU83101.1 - 0.035 12.4 0.7 0.075 11.3 0.0 1.7 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase ACPS PF01648.20 EAU83102.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Ago_PAZ PF18309.1 EAU83102.1 - 0.12 13.0 0.0 0.39 11.4 0.0 1.8 2 0 0 2 2 2 0 Argonaute PAZ domain ECH_1 PF00378.20 EAU83103.1 - 6.4e-32 110.8 0.0 8.9e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAU83103.1 - 4.7e-11 42.8 0.0 1.2e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 EAU83105.1 - 1.8e-55 188.2 0.0 6.4e-55 186.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU83105.1 - 2.6e-32 112.1 0.0 2.2e-22 79.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EAU83105.1 - 4.8e-06 26.7 0.1 8.3e-05 22.6 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EAU83105.1 - 2.6e-05 23.7 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAU83105.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EAU83105.1 - 0.0024 16.9 0.2 0.0081 15.1 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAU83105.1 - 0.0093 15.3 0.1 0.3 10.4 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EAU83105.1 - 0.02 13.7 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PEX11 PF05648.14 EAU83106.1 - 1.3e-15 57.5 0.3 7e-14 51.8 0.3 2.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HMG_box PF00505.19 EAU83107.2 - 3e-07 30.7 0.1 6e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU83107.2 - 1.1e-06 29.1 0.2 2.6e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 EAU83107.2 - 0.13 12.4 0.2 0.29 11.3 0.2 1.5 1 0 0 1 1 1 0 Protamine and protamine like NAD_binding_10 PF13460.6 EAU83108.1 - 3.3e-13 49.9 0.0 5.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAU83108.1 - 2e-11 43.9 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EAU83108.1 - 4e-07 29.7 0.0 9.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAU83108.1 - 7.4e-07 28.5 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAU83108.1 - 3.2e-05 23.2 0.0 5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 EAU83108.1 - 0.0002 21.8 0.0 0.00033 21.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EAU83108.1 - 0.00042 20.6 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.20 EAU83108.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 EAU83108.1 - 0.03 14.9 0.0 0.063 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 EAU83108.1 - 0.065 13.1 0.0 4.1 7.3 0.1 2.2 1 1 1 2 2 2 0 KR domain NAD_binding_10 PF13460.6 EAU83109.1 - 1.2e-09 38.4 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAU83109.1 - 4.5e-09 36.2 0.0 6.7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EAU83109.1 - 5e-06 26.8 0.0 9.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EAU83109.1 - 0.00011 21.3 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EAU83109.1 - 0.00028 20.1 0.1 0.00041 19.6 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 EAU83109.1 - 0.00035 20.8 0.0 0.00073 19.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 EAU83109.1 - 0.00061 19.3 0.1 0.0064 16.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAU83109.1 - 0.0057 16.6 0.3 2.3 8.1 0.1 2.2 1 1 1 2 2 2 2 KR domain Semialdhyde_dh PF01118.24 EAU83109.1 - 0.04 14.4 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EAU83109.1 - 0.088 12.2 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_3 PF03447.16 EAU83109.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ribosomal_L4 PF00573.22 EAU83110.1 - 1.8e-39 135.4 1.9 2.6e-39 134.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EAU83110.1 - 2.3e-29 101.2 5.6 5.6e-29 100.0 2.4 2.5 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PARP PF00644.20 EAU83112.2 - 9.1e-15 54.8 2.8 1.6e-11 44.1 2.8 3.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.14 EAU83112.2 - 0.027 14.4 3.3 0.027 14.4 3.3 4.7 5 1 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif CAP_N PF01213.19 EAU83112.2 - 7.3 6.0 6.7 13 5.2 6.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal YacG PF03884.14 EAU83112.2 - 8.8 6.2 19.9 0.36 10.6 2.4 3.5 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG PARP PF00644.20 EAU83113.2 - 0.027 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 EAU83114.1 - 9.2e-16 58.0 0.3 1.1e-09 38.2 0.3 3.0 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 EAU83115.2 - 4.7e-18 66.0 0.2 8.3e-18 65.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Mito_fiss_reg PF05308.11 EAU83116.1 - 0.33 11.0 4.5 0.67 10.0 4.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-FLZ PF04570.14 EAU83116.1 - 1.4 8.4 10.3 2.4 7.7 0.3 3.3 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 zf-MYND PF01753.18 EAU83116.1 - 3.7 7.7 27.9 4.7 7.4 4.7 4.5 2 2 0 2 2 2 0 MYND finger Coq4 PF05019.13 EAU83118.2 - 2.6e-100 334.3 0.0 3.4e-100 333.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 YibE_F PF07907.11 EAU83119.2 - 0.0083 15.7 0.3 0.0083 15.7 0.3 1.6 2 0 0 2 2 2 1 YibE/F-like protein DUF2157 PF09925.9 EAU83119.2 - 0.01 15.7 0.2 0.017 14.9 0.2 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) PLDc_2 PF13091.6 EAU83121.2 - 9.3e-13 48.2 0.0 5e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EAU83121.2 - 8.4e-08 32.1 0.6 0.011 15.9 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif F-box-like PF12937.7 EAU83123.1 - 1.4e-07 31.3 0.0 5.2e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU83123.1 - 0.00077 19.3 1.5 0.27 11.2 0.0 3.1 3 0 0 3 3 3 2 F-box domain PI3K_P85_iSH2 PF16454.5 EAU83123.1 - 0.12 11.9 4.7 0.081 12.5 2.8 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-Q PF13094.6 EAU83123.1 - 0.14 12.4 4.9 0.27 11.4 4.9 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1319 PF07028.11 EAU83123.1 - 0.26 11.5 2.1 9.4 6.5 1.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1319) Lebercilin PF15619.6 EAU83123.1 - 0.42 10.2 11.3 0.66 9.6 11.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease LRR_4 PF12799.7 EAU83123.1 - 2.5 8.7 9.5 10 6.7 0.1 4.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) p450 PF00067.22 EAU83133.2 - 9.3e-10 37.8 1.0 0.0068 15.2 0.1 3.1 2 1 1 3 3 3 3 Cytochrome P450 CDC45 PF02724.14 EAU83134.2 - 0.019 13.3 4.3 0.032 12.5 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EAU83134.2 - 0.037 12.3 4.5 0.055 11.7 4.5 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EAU83134.2 - 5.8 6.1 7.0 11 5.2 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.22 EAU83136.2 - 2.4e-61 207.9 0.0 4e-61 207.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EAU83138.2 - 3e-15 56.4 0.0 6.5e-15 55.3 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU83138.2 - 1.6e-10 40.8 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EAU83138.2 - 3.7e-05 24.8 0.0 6.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Lactonase PF10282.9 EAU83139.2 - 4.4e-35 121.5 0.0 9.5e-31 107.3 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller UPF0014 PF03649.13 EAU83140.2 - 4.9e-58 196.4 24.8 9.3e-44 149.6 7.5 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0014) DFRP_C PF16543.5 EAU83147.2 - 7.2e-31 106.5 1.1 7.2e-31 106.5 1.1 3.5 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EAU83147.2 - 5.8e-06 26.1 0.7 5.8e-06 26.1 0.7 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAU83147.2 - 8.3e-06 26.5 8.1 9.9e-05 23.0 2.8 2.9 1 1 1 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 EAU83147.2 - 5e-05 23.2 5.5 5e-05 23.2 5.5 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 EAU83147.2 - 0.00025 20.8 8.4 0.00031 20.5 1.2 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger F-box-like PF12937.7 EAU83147.2 - 0.0025 17.7 0.0 0.0078 16.1 0.0 1.8 2 0 0 2 2 2 1 F-box-like zf-CCCH_3 PF15663.5 EAU83147.2 - 0.0073 16.5 1.8 0.17 12.1 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger containing family Ndc1_Nup PF09531.10 EAU83147.2 - 0.045 12.5 2.8 0.063 12.0 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-CCCH_2 PF14608.6 EAU83147.2 - 0.63 10.6 8.9 0.43 11.1 3.5 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EAU83148.1 - 5.8e-39 133.2 2.6 1e-38 132.4 2.6 1.4 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EAU83148.1 - 2.9e-07 30.2 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAU83148.1 - 6.1e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 EAU83148.1 - 0.067 13.0 6.8 0.14 12.0 6.8 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAU83148.1 - 0.22 11.6 7.3 0.42 10.7 7.3 1.5 1 0 0 1 1 1 0 Zinc finger domain PI3K_P85_iSH2 PF16454.5 EAU83152.2 - 0.035 13.7 0.2 0.047 13.3 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ABC_membrane PF00664.23 EAU83155.1 - 2e-40 139.2 11.4 2.5e-40 138.9 11.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAU83155.1 - 5.7e-34 117.6 0.0 1.3e-33 116.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAU83155.1 - 5.5e-07 29.2 1.5 0.0011 18.5 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EAU83155.1 - 0.00035 20.9 0.1 0.0036 17.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU83155.1 - 0.0051 17.2 0.1 0.012 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAU83155.1 - 0.0062 17.0 0.0 0.074 13.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EAU83155.1 - 0.0063 16.4 0.1 0.14 12.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EAU83155.1 - 0.012 15.4 0.0 0.12 12.1 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.6 EAU83155.1 - 0.016 15.2 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EAU83155.1 - 0.022 14.7 0.0 0.38 10.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EAU83155.1 - 0.025 14.7 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EAU83155.1 - 0.039 13.9 0.0 0.15 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EAU83155.1 - 0.04 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 EAU83155.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 EAU83155.1 - 0.041 13.6 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_33 PF13671.6 EAU83155.1 - 0.047 13.8 0.0 0.8 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAU83155.1 - 0.053 14.0 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAU83155.1 - 0.084 13.4 0.0 0.34 11.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EAU83155.1 - 0.093 13.0 0.0 0.67 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EAU83155.1 - 0.14 12.4 1.5 1 9.6 0.4 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Lipase_GDSL_3 PF14606.6 EAU83156.2 - 0.43 10.7 6.9 0.31 11.1 4.8 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF150_C PF17384.2 EAU83156.2 - 0.47 10.6 10.6 20 5.4 7.8 3.7 2 1 0 2 2 2 0 RimP C-terminal SH3 domain DUF2415 PF10313.9 EAU83158.1 - 1.1e-06 28.5 0.0 5.5e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 EAU83158.1 - 1.1e-05 25.7 0.0 2.5 8.5 0.0 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU83158.1 - 0.15 11.0 0.0 28 3.5 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 EAU83158.1 - 0.19 12.7 1.1 2e+02 3.1 0.0 4.1 5 0 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 EAU83158.1 - 0.93 9.5 3.9 15 5.7 0.0 4.0 4 1 0 4 4 4 0 WD40-like Beta Propeller Repeat CENP-B_dimeris PF09026.10 EAU83158.1 - 2.5 8.5 7.7 4.9 7.6 7.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain F-box-like PF12937.7 EAU83161.2 - 0.081 12.8 0.2 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 F-box-like NACHT PF05729.12 EAU83162.2 - 2.3e-08 34.1 0.0 4.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83162.2 - 0.00035 21.0 0.1 0.00086 19.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU83162.2 - 0.001 19.3 0.0 0.018 15.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAU83162.2 - 0.091 13.2 0.0 0.22 11.9 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KH_6 PF15985.5 EAU83162.2 - 0.18 12.2 0.1 12 6.4 0.0 2.8 2 0 0 2 2 2 0 KH domain Macoilin PF09726.9 EAU83164.2 - 0.0011 17.7 12.9 0.0011 17.7 12.9 6.1 3 2 0 5 5 5 2 Macoilin family Atrophin-1 PF03154.15 EAU83164.2 - 0.0012 17.3 7.1 0.0012 17.3 7.1 9.7 6 3 1 8 8 8 1 Atrophin-1 family DUF641 PF04859.12 EAU83164.2 - 5.7 7.3 24.9 0.13 12.6 1.4 3.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) F-box-like PF12937.7 EAU83167.2 - 0.00085 19.2 0.2 0.0026 17.6 0.2 1.9 1 1 0 1 1 1 1 F-box-like UBX PF00789.20 EAU83168.1 - 0.13 12.5 0.0 0.46 10.7 0.0 1.9 1 0 0 1 1 1 0 UBX domain DUF2415 PF10313.9 EAU83170.2 - 1e-08 34.9 0.0 3.1e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) TFIIA PF03153.13 EAU83170.2 - 0.16 11.9 6.7 0.21 11.5 0.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.14 EAU83170.2 - 0.38 10.5 0.0 0.38 10.5 0.0 3.1 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Zn_Tnp_IS91 PF14319.6 EAU83172.1 - 0.68 10.0 8.0 62 3.7 8.0 2.4 1 1 0 1 1 1 0 Transposase zinc-binding domain HMG_box PF00505.19 EAU83173.1 - 1.3e-06 28.8 0.8 0.00092 19.6 0.1 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box Ferritin_2 PF13668.6 EAU83174.1 - 5.2e-17 62.3 0.1 7.6e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF900 PF05990.12 EAU83174.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ferritin-like PF12902.7 EAU83174.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like Myb_DNA-binding PF00249.31 EAU83174.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain HMG_box PF00505.19 EAU83176.1 - 2.7e-09 37.3 0.4 5e-09 36.4 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU83176.1 - 3.1e-06 27.7 0.1 8.8e-06 26.2 0.1 1.8 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EAU83177.2 - 7.4e-07 29.5 0.1 1.4e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 EAU83177.2 - 0.0004 19.7 0.1 0.00074 18.9 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 EAU83177.2 - 0.0054 17.3 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain Protamine_like PF06382.11 EAU83177.2 - 0.45 10.7 3.2 1.5 9.0 0.1 2.1 1 1 1 2 2 2 0 Protamine and protamine like DSPc PF00782.20 EAU83178.2 - 1.8e-23 82.8 0.0 3.2e-20 72.3 0.0 3.3 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAU83178.2 - 0.076 12.6 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ifi-6-16 PF06140.13 EAU83179.2 - 3.6e-06 26.8 23.0 3.6e-06 26.8 23.0 2.1 1 1 1 2 2 2 1 Interferon-induced 6-16 family GMC_oxred_N PF00732.19 EAU83180.1 - 7.7e-61 206.0 0.0 1.1e-60 205.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU83180.1 - 4.6e-33 114.8 0.0 7.5e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EAU83180.1 - 8e-07 28.4 0.1 1.2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EAU83180.1 - 0.0004 20.1 0.7 0.0033 17.1 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU83180.1 - 0.0009 19.4 0.7 0.0033 17.6 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU83180.1 - 0.00091 18.5 0.3 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU83180.1 - 0.0068 15.7 0.5 0.016 14.4 0.5 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EAU83180.1 - 0.02 14.1 0.1 0.092 12.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU83180.1 - 0.024 13.7 1.0 0.05 12.7 1.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EAU83180.1 - 0.043 12.5 0.3 0.079 11.6 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EAU83180.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NTP_transf_9 PF04248.12 EAU83182.1 - 2.6e-10 40.0 1.3 3.1e-10 39.8 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Tudor_2 PF18104.1 EAU83182.1 - 0.081 12.6 1.9 0.27 11.0 0.2 2.1 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain DUF202 PF02656.15 EAU83183.1 - 6e-14 52.2 5.3 7.8e-14 51.9 1.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF5539 PF17693.1 EAU83183.1 - 0.045 13.4 0.4 0.063 12.9 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) DnaJ_C PF01556.18 EAU83184.1 - 1.9e-38 131.9 0.4 2.5e-38 131.5 0.4 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAU83184.1 - 4.3e-28 97.2 1.9 8.5e-28 96.3 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain F_actin_cap_B PF01115.17 EAU83187.1 - 5.9e-107 356.7 0.0 6.8e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pro_isomerase PF00160.21 EAU83188.2 - 2.1e-50 171.1 0.1 2.3e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.20 EAU83189.1 - 2e-102 343.0 0.0 2.2e-102 342.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU83189.1 - 2.1e-14 53.4 0.1 2.6e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EAU83189.1 - 2e-05 24.8 0.0 0.14 12.4 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU83189.1 - 7.2e-05 22.4 0.0 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 Ras family Gtr1_RagA PF04670.12 EAU83189.1 - 0.0019 17.6 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 EAU83189.1 - 0.0024 17.3 0.1 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 EAU83189.1 - 0.022 14.5 0.0 0.072 12.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EAU83189.1 - 0.048 13.4 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EAU83189.1 - 0.051 13.1 0.1 1.1 8.7 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain BCD PF15461.6 EAU83189.1 - 0.09 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase RsgA_GTPase PF03193.16 EAU83189.1 - 0.15 11.9 0.1 21 5.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase Stomoxyn PF11585.8 EAU83191.1 - 0.088 12.8 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn GNVR PF13807.6 EAU83191.1 - 0.27 11.2 8.3 3.8 7.5 0.6 2.6 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase GAS PF13851.6 EAU83191.1 - 2.9 7.2 31.4 2.6 7.3 18.4 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.6 EAU83191.1 - 4.7 7.4 27.1 0.84 9.8 4.3 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Aminotran_1_2 PF00155.21 EAU83192.1 - 5.7e-15 55.3 0.0 8.3e-08 31.8 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.7 EAU83192.1 - 6.1e-06 25.3 0.0 7.7e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase PEP-utilisers_N PF05524.13 EAU83192.1 - 0.15 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Pkinase PF00069.25 EAU83193.2 - 2.5e-44 151.7 0.0 2.2e-32 112.5 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU83193.2 - 6.1e-24 84.7 0.0 4.4e-19 68.8 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU83193.2 - 5.9e-05 22.0 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU83193.2 - 0.00074 19.5 0.1 0.11 12.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU83193.2 - 0.0065 15.8 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like SelP_N PF04592.14 EAU83193.2 - 1.1 8.6 4.4 2.5 7.4 4.4 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HMG_box PF00505.19 EAU83194.2 - 5.6e-08 33.1 2.0 9.5e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 EAU83194.2 - 1e-07 31.5 0.5 2e-07 30.5 0.1 1.6 2 0 0 2 2 2 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 EAU83194.2 - 4.1e-06 27.3 0.1 8.5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain SOBP PF15279.6 EAU83194.2 - 0.02 15.5 9.5 0.025 15.2 9.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Protamine_like PF06382.11 EAU83194.2 - 0.035 14.3 0.1 0.035 14.3 0.1 2.1 1 1 1 2 2 2 0 Protamine and protamine like MAP65_ASE1 PF03999.12 EAU83194.2 - 0.18 10.5 5.7 0.2 10.3 5.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GREB1 PF15782.5 EAU83194.2 - 1.5 5.9 4.2 1.8 5.6 4.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Epimerase PF01370.21 EAU83195.2 - 7.6e-06 25.6 0.0 0.00062 19.3 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EAU83195.2 - 6e-05 23.3 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EAU83195.2 - 8.6e-05 21.7 0.0 0.00016 20.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EAU83195.2 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NmrA PF05368.13 EAU83195.2 - 0.00069 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EAU83195.2 - 0.0085 16.5 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EAU83195.2 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 EAU83195.2 - 0.11 11.7 0.0 0.27 10.4 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein IL34 PF15036.6 EAU83197.2 - 0.14 12.2 0.0 0.26 11.3 0.0 1.5 1 1 0 1 1 1 0 Interleukin 34 p450 PF00067.22 EAU83198.2 - 7.7e-62 209.5 0.0 9.7e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NTP_transf_9 PF04248.12 EAU83200.1 - 5.4e-32 109.5 0.0 7.3e-26 89.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Glyco_transf_22 PF03901.17 EAU83201.2 - 5.6e-40 137.8 23.5 7.7e-40 137.4 23.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_61 PF03443.14 EAU83203.1 - 1e-56 192.2 0.0 1.1e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ala_racemase_N PF01168.20 EAU83204.2 - 2e-18 66.9 0.0 2.1e-17 63.5 0.0 1.9 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Popeye PF04831.13 EAU83205.2 - 4.9 7.3 6.3 16 5.7 6.0 1.9 2 0 0 2 2 2 0 Popeye protein conserved region p450 PF00067.22 EAU83206.2 - 1.3e-49 169.2 0.0 1.6e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3823 PF12866.7 EAU83206.2 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain Nop14 PF04147.12 EAU83207.2 - 0.21 9.8 11.8 0.29 9.3 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 EAU83207.2 - 0.36 10.8 13.4 0.72 9.8 13.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 EAU83212.2 - 3.3e-07 29.4 0.0 4.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.6 EAU83213.1 - 0.00056 19.7 0.0 0.032 14.0 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease Sirohm_synth_M PF14824.6 EAU83213.1 - 0.26 10.8 2.2 0.27 10.7 0.2 2.0 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Atg14 PF10186.9 EAU83218.2 - 0.0011 18.2 1.0 0.0024 17.0 1.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 EAU83218.2 - 0.0045 17.2 9.1 0.0081 16.4 9.1 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 EAU83218.2 - 0.018 15.3 5.1 0.046 14.0 5.1 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 EAU83218.2 - 0.05 12.3 0.4 0.072 11.7 0.4 1.1 1 0 0 1 1 1 0 AAA domain PI3K_P85_iSH2 PF16454.5 EAU83218.2 - 0.054 13.1 4.7 0.14 11.8 4.7 1.7 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TSC22 PF01166.18 EAU83218.2 - 0.075 13.3 0.4 0.23 11.8 0.4 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family PspA_IM30 PF04012.12 EAU83218.2 - 0.089 12.4 3.4 0.21 11.1 3.5 1.6 1 1 0 1 1 1 0 PspA/IM30 family KLRAQ PF10205.9 EAU83218.2 - 0.11 12.7 4.6 0.25 11.6 4.6 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF4407 PF14362.6 EAU83218.2 - 0.16 11.3 4.0 0.24 10.7 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 EAU83218.2 - 0.16 11.3 7.3 0.27 10.6 7.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding GreA_GreB_N PF03449.15 EAU83218.2 - 0.19 11.9 1.2 0.44 10.7 1.0 1.8 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal zf-CpG_bind_C PF12269.8 EAU83218.2 - 0.2 11.4 2.4 0.28 10.9 1.8 1.5 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DUF4201 PF13870.6 EAU83218.2 - 0.2 11.4 7.1 0.35 10.6 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) bZIP_2 PF07716.15 EAU83218.2 - 0.23 11.6 1.3 0.57 10.3 1.3 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Spc7 PF08317.11 EAU83218.2 - 0.27 10.1 7.8 0.74 8.6 6.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein CtIP_N PF10482.9 EAU83218.2 - 0.35 10.9 5.5 6.1 6.9 5.5 2.4 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain FapA PF03961.13 EAU83218.2 - 0.38 9.3 3.2 0.59 8.7 3.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A LPP PF04728.13 EAU83218.2 - 0.43 11.0 4.5 19 5.8 0.2 2.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper MAD PF05557.13 EAU83218.2 - 0.44 8.9 8.5 0.65 8.3 8.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc24 PF08286.11 EAU83218.2 - 0.75 10.1 9.4 1.7 8.9 1.2 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.9 EAU83218.2 - 0.96 9.5 11.3 2.4 8.2 4.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 EAU83218.2 - 1.4 9.2 4.8 3.2 8.0 4.8 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 EAU83218.2 - 1.7 6.5 3.8 2.3 6.1 3.8 1.1 1 0 0 1 1 1 0 Prominin DUF724 PF05266.14 EAU83218.2 - 2.5 7.9 5.8 4.2 7.1 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6_N PF17675.1 EAU83218.2 - 4.1 7.9 14.5 6.8 7.2 1.9 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region LRR_6 PF13516.6 EAU83219.2 - 0.028 14.4 14.0 37 4.7 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich repeat KDZ PF18758.1 EAU83220.2 - 8.7e-45 153.0 1.3 8.7e-45 153.0 1.3 2.0 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU83220.2 - 6.3e-22 77.8 0.1 1.5e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU83220.2 - 0.00097 19.3 0.2 0.0025 17.9 0.2 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EAU83223.2 - 3.5e-48 164.2 0.2 8.6e-48 162.9 0.0 1.6 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase HA PF03457.14 EAU83223.2 - 0.051 13.9 0.6 0.22 11.9 0.6 2.1 1 0 0 1 1 1 0 Helicase associated domain DivIC PF04977.15 EAU83223.2 - 7.8 6.3 8.3 0.21 11.4 0.2 2.6 3 0 0 3 3 3 0 Septum formation initiator Fungal_trans PF04082.18 EAU83233.2 - 5.1e-23 81.4 0.1 1.1e-22 80.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU83233.2 - 0.043 13.9 7.4 0.036 14.2 3.7 2.4 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4907 PF16250.5 EAU83233.2 - 0.078 12.9 0.1 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4907) SelP_N PF04592.14 EAU83233.2 - 1.1 8.6 15.5 2.1 7.7 15.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Polysacc_deac_1 PF01522.21 EAU83234.2 - 3.1e-25 88.5 0.1 6e-25 87.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HNH_2 PF13391.6 EAU83234.2 - 0.025 14.7 1.1 0.089 12.9 0.0 2.3 2 1 1 3 3 3 0 HNH endonuclease Vps16_N PF04841.13 EAU83234.2 - 0.057 12.2 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region DUF2334 PF10096.9 EAU83234.2 - 0.065 12.9 0.2 0.091 12.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) EPV_E5 PF08135.11 EAU83235.1 - 4.2 7.8 6.9 0.45 10.9 2.2 1.8 2 0 0 2 2 2 0 Major transforming protein E5 family GST_N PF02798.20 EAU83236.1 - 3.1e-20 72.3 0.0 5.8e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU83236.1 - 3.6e-18 65.8 0.0 5.8e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU83236.1 - 6.1e-15 55.2 0.1 9.7e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAU83236.1 - 7.3e-12 45.4 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAU83236.1 - 9.5e-07 29.0 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU83236.1 - 7.1e-06 25.9 0.2 2.1e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EAU83236.1 - 0.0046 17.7 0.0 0.0089 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EAU83236.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.26 EAU83237.1 - 1.6e-13 50.8 0.0 3.5e-13 49.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU83237.1 - 7.1e-11 42.0 0.0 1.3e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EAU83237.1 - 0.0097 17.0 0.0 0.021 15.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CxC1 PF18802.1 EAU83239.2 - 3.4e-10 40.0 0.5 5.4e-10 39.4 0.5 1.2 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU83239.2 - 8.4e-05 22.7 0.7 0.00014 22.0 0.7 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF3295 PF11702.8 EAU83240.2 - 2.8e-09 36.9 2.4 2.8e-09 36.9 2.4 7.5 5 3 0 5 5 5 1 Protein of unknown function (DUF3295) SUIM_assoc PF16619.5 EAU83240.2 - 0.0034 17.4 38.1 0.22 11.6 0.0 8.3 4 2 2 6 6 6 2 Unstructured region C-term to UIM in Ataxin3 Plavaka PF18759.1 EAU83243.2 - 1.7e-24 86.7 0.0 3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase UCH PF00443.29 EAU83244.1 - 0.0083 15.6 1.3 0.04 13.4 1.3 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IL12p40_C PF10420.9 EAU83245.1 - 0.12 12.8 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus DivIC PF04977.15 EAU83245.1 - 0.17 11.7 0.1 0.46 10.3 0.1 1.7 1 0 0 1 1 1 0 Septum formation initiator Plavaka PF18759.1 EAU83246.2 - 3.1e-41 141.7 0.0 7.4e-41 140.4 0.0 1.6 2 0 0 2 2 2 1 Plavaka transposase NinG PF05766.12 EAU83246.2 - 0.44 10.5 3.4 0.8 9.6 3.4 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein RNF220 PF15926.5 EAU83246.2 - 5.8 6.4 9.2 0.2 11.3 0.5 2.4 3 0 0 3 3 3 0 E3 ubiquitin-protein ligase RNF220 TRCF PF03461.15 EAU83248.1 - 0.066 13.6 0.2 0.17 12.3 0.2 1.7 1 0 0 1 1 1 0 TRCF domain Myb_DNA-bind_4 PF13837.6 EAU83248.1 - 0.07 13.5 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PBP1_TM PF14812.6 EAU83248.1 - 2.4 8.6 10.7 1.1 9.7 0.7 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med26_C PF15693.5 EAU83248.1 - 3.4 7.8 8.1 0.094 12.9 0.4 2.1 2 1 0 2 2 2 0 Mediator complex subunit 26 C-terminal DDE_Tnp_4 PF13359.6 EAU83249.2 - 7e-29 100.5 0.0 9.4e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 EAU83249.2 - 6.5e-20 71.6 0.0 1.5e-19 70.4 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.21 EAU83249.2 - 3.2e-08 33.5 0.1 1.5e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Transposase DDE domain zf-H2C2_2 PF13465.6 EAU83250.2 - 0.069 13.6 0.3 0.069 13.6 0.3 3.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 EAU83250.2 - 6.8 7.4 16.6 0.29 11.7 1.6 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type ADH_zinc_N PF00107.26 EAU83251.2 - 2.9e-11 43.5 0.0 4.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU83251.2 - 8e-11 41.8 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EAU83251.2 - 0.056 13.3 0.1 0.17 11.8 0.1 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_N PF08240.12 EAU83252.2 - 2.5e-12 46.6 0.1 4e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU83252.2 - 2.8e-12 46.7 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU83252.2 - 0.054 14.5 0.0 0.11 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GST_C PF00043.25 EAU83254.2 - 5.7e-14 52.1 0.1 9.6e-14 51.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU83254.2 - 2.2e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU83254.2 - 7.6e-06 26.0 0.1 2e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SLATT_fungal PF18142.1 EAU83255.2 - 2.4e-38 130.8 0.1 3.8e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain XRN_M PF17846.1 EAU83256.2 - 2.2e-101 340.0 7.6 4.5e-101 339.0 7.6 1.5 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EAU83256.2 - 7.7e-84 280.9 0.0 1.5e-83 280.0 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EAU83256.2 - 7.4e-76 254.2 0.0 1.5e-75 253.2 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EAU83256.2 - 7.9e-32 109.3 0.0 2.4e-31 107.8 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EAU83256.2 - 7.1e-23 80.5 0.4 1.9e-22 79.1 0.4 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EAU83256.2 - 3.8e-09 36.5 0.5 8.2e-09 35.4 0.5 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 LexA_DNA_bind PF01726.16 EAU83256.2 - 0.026 14.3 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain GMP_synt_C PF00958.22 EAU83257.2 - 4.6e-45 151.6 0.1 9.8e-45 150.6 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EAU83257.2 - 3.6e-35 121.4 0.0 7.5e-35 120.4 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EAU83257.2 - 4.6e-10 39.0 0.1 2.8e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EAU83257.2 - 1.8e-08 34.4 0.0 4.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EAU83257.2 - 0.0013 17.6 0.1 0.0022 16.9 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 EAU83257.2 - 0.0023 17.5 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) QueC PF06508.13 EAU83257.2 - 0.0053 16.3 0.0 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 EAU83257.2 - 0.012 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 EAU83257.2 - 0.022 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 PP-loop family sCache_like PF16736.5 EAU83257.2 - 0.043 13.9 0.1 0.075 13.1 0.1 1.3 1 0 0 1 1 1 0 Single Cache-like PAPS_reduct PF01507.19 EAU83257.2 - 0.09 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Myb_DNA-binding PF00249.31 EAU83258.1 - 3.9e-39 132.6 8.6 1.5e-13 50.7 0.7 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU83258.1 - 3e-30 104.2 1.6 9.1e-13 48.3 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EAU83258.1 - 2.5e-05 24.1 0.0 0.18 11.7 0.0 2.7 2 1 0 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 EAU83258.1 - 0.0025 17.8 0.1 11 6.2 0.1 3.2 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EAU83258.1 - 0.0098 16.1 0.1 4.3 7.6 0.1 3.1 3 1 0 3 3 3 1 Rap1 Myb domain Glyco_hydro_12 PF01670.16 EAU83258.1 - 0.023 14.7 0.4 0.038 14.0 0.4 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 MADF_DNA_bdg PF10545.9 EAU83258.1 - 0.027 14.8 1.7 13 6.1 0.1 3.6 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 EAU83258.1 - 0.031 14.3 0.0 5.5 7.0 0.0 3.0 1 1 2 3 3 3 0 SLIDE SANT_DAMP1_like PF16282.5 EAU83258.1 - 0.032 14.4 0.6 1.6 9.0 0.0 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EAU83258.1 - 0.091 13.1 6.4 0.81 10.1 0.9 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Chorion_2 PF03964.15 EAU83258.1 - 0.59 11.0 7.6 3.9 8.4 0.7 2.7 2 0 0 2 2 2 0 Chorion family 2 Aldose_epim PF01263.20 EAU83259.1 - 1.3e-22 80.5 0.0 2.7e-22 79.4 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase Polysacc_deac_1 PF01522.21 EAU83261.2 - 1.2e-21 76.9 0.0 2.3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.18 EAU83262.2 - 7.6e-23 80.9 0.1 5.8e-22 78.0 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 EAU83262.2 - 0.0071 16.5 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 EAU83262.2 - 0.025 14.7 0.2 0.053 13.6 0.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC32 PF14989.6 EAU83262.2 - 1.8 8.5 4.2 0.43 10.6 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing 32 zf-C2H2_10 PF16588.5 EAU83263.2 - 0.002 17.8 0.5 0.0037 17.0 0.5 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 EAU83263.2 - 0.083 13.0 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF3510 PF12022.8 EAU83263.2 - 0.09 13.2 0.3 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) PRKG1_interact PF15898.5 EAU83263.2 - 0.22 12.4 6.4 6.1 7.8 0.8 2.7 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RGS-like PF09128.11 EAU83263.2 - 5.7 6.6 6.0 9.1 5.9 0.9 2.7 2 1 0 2 2 2 0 Regulator of G protein signalling-like domain RbsD_FucU PF05025.13 EAU83264.1 - 0.03 14.7 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family PEP_hydrolase PF09370.10 EAU83264.1 - 0.15 11.3 0.1 0.27 10.4 0.0 1.4 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like p450 PF00067.22 EAU83265.2 - 1.1e-57 195.9 0.0 3.8e-50 171.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EAU83268.1 - 4.6e-78 263.0 0.0 5.9e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SR-25 PF10500.9 EAU83272.2 - 0.029 14.0 3.8 0.047 13.3 3.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KDZ PF18758.1 EAU83273.2 - 1.8e-57 194.5 0.0 2.9e-57 193.8 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase PHA_synth_III_E PF09712.10 EAU83273.2 - 0.4 9.7 7.6 0.33 10.0 0.1 2.5 2 1 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Peptidase_S30 PF01577.16 EAU83274.1 - 0.036 13.7 4.0 0.063 12.9 4.0 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease Macoilin PF09726.9 EAU83274.1 - 0.63 8.5 5.6 0.8 8.2 5.6 1.0 1 0 0 1 1 1 0 Macoilin family Importin_rep_4 PF18808.1 EAU83277.1 - 1.7 8.9 6.9 4.9 7.5 3.2 3.2 4 0 0 4 4 4 0 Importin repeat UPF0561 PF10573.9 EAU83278.1 - 0.15 12.2 2.0 0.18 11.9 1.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 KDZ PF18758.1 EAU83280.2 - 1.4e-45 155.6 0.6 2.9e-45 154.6 0.6 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU83280.2 - 4e-09 36.6 2.0 7.6e-09 35.7 0.5 2.3 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 EAU83282.2 - 1.4e-11 44.4 0.0 2e-08 34.0 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily S10_plectin PF03501.15 EAU83289.2 - 3.6e-43 145.5 0.1 5.4e-43 145.0 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 EAU83289.2 - 0.056 13.3 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB O-FucT PF10250.9 EAU83290.2 - 3.9e-05 23.5 0.0 0.0031 17.3 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase SnoaL_2 PF12680.7 EAU83293.1 - 0.0016 19.0 2.4 0.0034 18.0 2.0 1.8 2 1 0 2 2 2 1 SnoaL-like domain Cytochrom_C PF00034.21 EAU83294.1 - 2.5e-10 41.4 0.0 3.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EAU83294.1 - 3e-08 33.9 1.6 3.2e-07 30.6 1.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EAU83294.1 - 0.00086 19.0 0.2 0.0042 16.8 0.0 2.0 2 1 0 2 2 2 1 Cytochrome c-550 domain DUF4670 PF15709.5 EAU83295.2 - 0.00033 20.1 0.2 0.0004 19.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4670) DUF5102 PF17104.5 EAU83295.2 - 0.15 12.1 2.3 0.19 11.7 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) COX14 PF14880.6 EAU83295.2 - 0.33 10.8 1.5 0.65 9.9 1.5 1.5 1 1 0 1 1 1 0 Cytochrome oxidase c assembly LCE PF14672.6 EAU83295.2 - 0.51 11.0 1.7 0.79 10.4 1.7 1.4 1 1 0 1 1 1 0 Late cornified envelope PBP1_TM PF14812.6 EAU83295.2 - 5.8 7.4 9.3 2.6 8.5 4.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 EAU83297.2 - 3e-36 125.1 33.4 3e-36 125.1 33.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 EAU83297.2 - 0.0065 15.8 7.1 0.0065 15.8 7.1 2.9 2 1 1 3 3 3 1 Sporulation factor SpoIIGA Hydrolase_4 PF12146.8 EAU83299.2 - 3.7e-14 52.6 0.0 1.5e-10 40.8 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAU83299.2 - 2.9e-09 36.9 0.1 0.00033 20.4 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU83299.2 - 2e-06 28.6 0.1 8.1e-06 26.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EAU83299.2 - 4.6e-05 23.0 0.0 0.00023 20.7 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EAU83299.2 - 0.001 18.7 0.0 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 EAU83299.2 - 0.0022 17.9 0.0 0.51 10.1 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EAU83299.2 - 0.15 11.7 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 EAU83299.2 - 0.24 10.0 0.2 2 7.0 0.1 2.3 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) GST_N PF02798.20 EAU83301.1 - 2.1e-18 66.4 0.2 8.8e-18 64.4 0.1 2.1 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU83301.1 - 1.7e-15 57.2 0.1 3.9e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU83301.1 - 1.9e-14 53.6 0.4 2.9e-14 53.1 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAU83301.1 - 4.2e-10 39.8 0.0 9.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU83301.1 - 1.5e-09 37.8 0.0 3.5e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU83301.1 - 2.5e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Polysacc_deac_1 PF01522.21 EAU83302.2 - 4.3e-25 88.0 0.0 6.7e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase p450 PF00067.22 EAU83306.2 - 1.7e-72 244.7 0.0 2.5e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1730 PF08331.10 EAU83306.2 - 0.19 11.6 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) Glyco_hydro_106 PF17132.4 EAU83306.2 - 0.25 9.6 0.0 0.35 9.1 0.0 1.1 1 0 0 1 1 1 0 alpha-L-rhamnosidase TraL PF07178.11 EAU83307.2 - 2.1 8.8 8.2 6 7.4 0.9 3.3 3 0 0 3 3 3 0 TraL protein MIS13 PF08202.11 EAU83308.2 - 1.9e-21 76.6 2.3 8.9e-21 74.5 0.2 2.7 3 0 0 3 3 3 1 Mis12-Mtw1 protein family GST_N PF02798.20 EAU83309.1 - 6.6e-19 68.0 0.0 1.3e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU83309.1 - 2.2e-17 63.2 0.0 3.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU83309.1 - 2.3e-11 43.7 0.1 5.2e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAU83309.1 - 2.3e-11 43.8 0.0 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAU83309.1 - 1.3e-06 28.6 0.0 2.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU83309.1 - 2.1e-06 27.7 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.22 EAU83310.2 - 2.1e-65 221.3 0.0 1.3e-43 149.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 F-box-like PF12937.7 EAU83314.1 - 6.1e-12 45.2 2.7 1.5e-11 44.0 2.7 1.7 1 1 0 1 1 1 1 F-box-like BrnA_antitoxin PF14384.6 EAU83314.1 - 0.016 15.7 0.1 0.047 14.2 0.0 1.8 2 0 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system LRR_4 PF12799.7 EAU83314.1 - 0.095 13.2 5.2 18 5.9 0.8 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EAU83314.1 - 0.13 12.2 4.3 0.28 11.1 0.1 2.4 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 EAU83314.1 - 1.1 10.1 4.1 8.2 7.4 0.5 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat ABC2_membrane PF01061.24 EAU83316.2 - 2.8e-35 121.6 20.9 2.8e-35 121.6 20.9 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 EAU83316.2 - 2.1e-28 99.5 0.1 6.4e-28 98.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EAU83316.2 - 3e-06 27.3 0.3 0.032 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 EAU83316.2 - 0.00016 22.0 10.7 0.00016 22.0 10.7 3.5 4 0 0 4 4 2 1 EGF-like domain AAA_29 PF13555.6 EAU83316.2 - 0.00069 19.3 0.1 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAU83316.2 - 0.0019 18.1 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 EAU83316.2 - 0.0044 16.2 27.5 0.0092 15.1 27.5 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.6 EAU83316.2 - 0.0087 15.7 0.0 0.023 14.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EAU83316.2 - 0.026 13.9 0.0 0.14 11.6 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAU83316.2 - 0.028 14.8 0.1 0.078 13.4 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain AAA_28 PF13521.6 EAU83316.2 - 0.028 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EAU83316.2 - 0.046 13.6 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 EAU83316.2 - 0.071 13.4 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAU83316.2 - 0.081 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 NACHT domain ATP-synt_ab PF00006.25 EAU83316.2 - 0.1 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 EAU83316.2 - 0.12 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EAU83316.2 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU83316.2 - 0.13 12.8 0.1 0.27 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain GBP PF02263.19 EAU83316.2 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Ank_4 PF13637.6 EAU83317.2 - 8e-13 48.6 0.5 9.7e-05 22.8 0.0 4.3 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EAU83317.2 - 6.1e-11 42.3 0.3 5.3e-05 23.5 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAU83317.2 - 9.9e-10 38.9 0.0 7.8e-09 36.0 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU83317.2 - 1.7e-09 37.1 0.4 0.015 15.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAU83317.2 - 7.8e-07 29.3 0.3 0.0002 21.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) zf-MYND PF01753.18 EAU83318.2 - 8.8e-11 41.7 15.0 1.7e-10 40.8 15.0 1.5 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 EAU83318.2 - 4.4e-07 30.3 0.0 0.038 14.6 0.0 4.2 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAU83318.2 - 6.2e-06 26.4 0.0 0.00011 22.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAU83318.2 - 6.8e-06 26.3 0.0 1.9 8.9 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU83318.2 - 1.3e-05 25.2 0.1 0.02 15.4 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 EAU83318.2 - 0.00026 21.5 0.0 0.0016 19.0 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) DUF2256 PF10013.9 EAU83318.2 - 0.059 13.5 6.4 0.12 12.6 6.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C6H2 PF15801.5 EAU83318.2 - 0.073 13.4 11.1 0.15 12.4 11.1 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 EAU83318.2 - 1.6 6.5 3.6 2.2 6.0 3.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cation_ATPase PF13246.6 EAU83329.1 - 0.036 14.2 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Tropomyosin_1 PF12718.7 EAU83331.1 - 0.0022 18.2 1.1 0.0049 17.0 1.1 1.5 1 0 0 1 1 1 1 Tropomyosin like MscS_porin PF12795.7 EAU83331.1 - 0.017 14.7 1.6 0.034 13.7 1.6 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Zn_ribbon_SprT PF17283.2 EAU83331.1 - 0.66 9.9 4.7 1.4 8.9 4.7 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain P3A PF08727.11 EAU83331.1 - 5.2 6.5 12.5 24 4.4 0.5 3.6 1 1 2 3 3 3 0 Poliovirus 3A protein like zf-MYND PF01753.18 EAU83334.1 - 7.6e-11 41.9 9.5 2e-10 40.6 9.5 1.8 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU83334.1 - 0.0023 18.2 5.1 0.0045 17.3 5.1 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf_C2H2_13 PF18508.1 EAU83334.1 - 0.017 14.7 3.0 0.17 11.5 0.4 2.7 1 1 1 2 2 2 0 Zinc finger domain Ribosomal_S14 PF00253.21 EAU83334.1 - 2.9 7.7 6.0 0.27 11.0 1.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e Syntaxin-6_N PF09177.11 EAU83336.1 - 0.0039 17.7 0.2 0.011 16.3 0.1 1.6 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF1627 PF07789.12 EAU83336.1 - 0.0042 16.7 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1627) DUF4201 PF13870.6 EAU83336.1 - 0.019 14.7 0.2 0.023 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF2564 PF10819.8 EAU83336.1 - 0.069 13.5 0.5 0.1 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Kre28 PF17097.5 EAU83336.1 - 0.14 11.1 1.4 0.16 10.9 1.4 1.0 1 0 0 1 1 1 0 Spindle pole body component HalX PF08663.10 EAU83336.1 - 0.17 12.2 0.8 0.31 11.4 0.6 1.5 1 1 1 2 2 2 0 HalX domain PPI_Ypi1 PF07491.11 EAU83337.2 - 3.2e-25 87.7 0.3 9.3e-25 86.2 0.3 1.8 1 0 0 1 1 1 1 Protein phosphatase inhibitor FAM104 PF15434.6 EAU83337.2 - 0.032 14.8 3.3 0.033 14.7 2.0 1.8 2 0 0 2 2 2 0 Family 104 CDC45 PF02724.14 EAU83337.2 - 0.2 9.9 0.4 0.21 9.8 0.4 1.0 1 0 0 1 1 1 0 CDC45-like protein IDO PF01231.18 EAU83338.1 - 3.6e-132 441.2 0.0 4.5e-132 440.9 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 EAU83338.1 - 0.032 13.0 0.0 2.7 6.7 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1864) DUF4140 PF13600.6 EAU83339.2 - 0.41 11.1 6.1 1.1 9.7 0.1 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 EAU83339.2 - 1 9.4 7.4 1 9.4 5.5 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 EAU83339.2 - 2.7 8.0 7.1 8.7 6.3 7.1 1.8 1 1 0 1 1 1 0 Prefoldin subunit KDZ PF18758.1 EAU83342.2 - 8e-46 156.4 0.0 4.5e-23 82.0 0.0 2.4 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU83342.2 - 2e-40 137.3 0.2 5.2e-39 132.7 0.0 2.3 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU83342.2 - 6.8e-06 26.2 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases FYVE PF01363.21 EAU83342.2 - 0.2 11.8 4.0 0.74 10.0 4.0 2.0 1 0 0 1 1 1 0 FYVE zinc finger Cauli_VI PF01693.16 EAU83345.1 - 0.00081 19.6 0.1 0.0019 18.4 0.1 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin Menin PF05053.13 EAU83345.1 - 0.2 10.0 0.2 0.29 9.4 0.2 1.2 1 0 0 1 1 1 0 Menin C2 PF00168.30 EAU83349.2 - 3.6e-08 33.6 0.0 5.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 C2 domain PS_Dcarbxylase PF02666.15 EAU83350.1 - 2.9e-60 203.2 0.0 4.3e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EAU83350.1 - 1.2e-18 67.3 0.0 2.6e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EAU83350.1 - 0.0014 19.1 0.1 0.0036 17.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EAU83350.1 - 0.034 14.1 0.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain zf-MYND PF01753.18 EAU83356.2 - 2.2e-09 37.3 4.1 3.5e-09 36.6 4.1 1.3 1 0 0 1 1 1 1 MYND finger HNF-1_N PF04814.13 EAU83361.2 - 0.095 13.3 5.3 0.29 11.7 5.3 1.8 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Ndc1_Nup PF09531.10 EAU83361.2 - 0.63 8.7 6.8 0.95 8.1 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PPIP5K2_N PF18086.1 EAU83362.2 - 0.06 13.5 0.1 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Polysacc_deac_1 PF01522.21 EAU83363.2 - 7.3e-24 84.0 0.0 1.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase YtpI PF14007.6 EAU83364.2 - 0.046 13.8 0.1 0.07 13.3 0.1 1.3 1 0 0 1 1 1 0 YtpI-like protein DUF3533 PF12051.8 EAU83366.2 - 2.2e-87 293.4 8.8 5.5e-86 288.9 8.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3533) DUF3533 PF12051.8 EAU83367.2 - 8.6e-87 291.5 8.5 1.1e-86 291.2 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Polysacc_deac_1 PF01522.21 EAU83368.2 - 3e-26 91.7 0.0 5.6e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase APH PF01636.23 EAU83369.2 - 2.4e-08 34.2 0.0 5.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family HTH_3 PF01381.22 EAU83369.2 - 4.2e-05 23.5 0.2 9.3e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EAU83369.2 - 0.003 17.5 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EAU83369.2 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Fructosamin_kin PF03881.14 EAU83369.2 - 0.088 12.0 0.9 0.89 8.7 0.1 2.2 2 0 0 2 2 2 0 Fructosamine kinase HTH_24 PF13412.6 EAU83369.2 - 0.089 12.4 0.2 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding EcKinase PF02958.20 EAU83369.2 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-MYND PF01753.18 EAU83370.2 - 2e-09 37.4 11.6 4e-09 36.4 11.6 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 EAU83371.2 - 9.3e-09 35.2 4.3 2e-08 34.1 4.3 1.5 1 0 0 1 1 1 1 MYND finger CitG PF01874.16 EAU83371.2 - 0.0056 16.4 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 ATP:dephospho-CoA triphosphoribosyl transferase Ribosomal_L14e PF01929.17 EAU83371.2 - 0.13 12.8 0.0 19 5.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L14 DUF4267 PF14087.6 EAU83373.2 - 0.051 13.6 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) SWM_repeat PF13753.6 EAU83374.1 - 0.038 14.1 0.1 0.091 12.9 0.1 1.6 1 0 0 1 1 1 0 Putative flagellar system-associated repeat Lon_C PF05362.13 EAU83375.2 - 6.3e-64 215.3 0.4 2.3e-63 213.5 0.5 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EAU83375.2 - 2.9e-23 82.8 2.8 4.5e-23 82.2 0.1 2.6 3 1 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EAU83375.2 - 2.9e-17 63.3 0.0 1.9e-16 60.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EAU83375.2 - 1.1e-06 28.5 0.2 3.2e-06 27.0 0.0 2.0 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 EAU83375.2 - 3.1e-05 24.3 0.0 0.00016 22.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAU83375.2 - 0.00021 21.3 0.0 0.00096 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU83375.2 - 0.00037 20.9 0.3 0.0023 18.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EAU83375.2 - 0.0043 17.2 0.0 0.041 14.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EAU83375.2 - 0.021 15.4 1.3 0.035 14.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain ClpB_D2-small PF10431.9 EAU83375.2 - 0.023 14.8 1.2 0.065 13.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein DNTTIP1_dimer PF18192.1 EAU83375.2 - 0.073 13.4 0.8 0.73 10.2 0.1 2.7 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain Neur_chan_memb PF02932.16 EAU83375.2 - 0.5 10.4 8.1 0.58 10.2 0.1 3.3 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region MIEAP PF16026.5 EAU83375.2 - 2.2 8.5 5.4 0.41 10.8 0.1 2.4 2 1 0 2 2 2 0 Mitochondria-eating protein Mito_fiss_reg PF05308.11 EAU83376.1 - 1.2 9.2 3.7 1.8 8.6 3.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-MYND PF01753.18 EAU83378.2 - 2.9e-09 36.9 4.2 6.3e-09 35.8 4.2 1.5 1 0 0 1 1 1 1 MYND finger Leuk-A4-hydro_C PF09127.11 EAU83378.2 - 0.15 12.1 0.0 6.7 6.8 0.0 3.0 3 0 0 3 3 3 0 Leukotriene A4 hydrolase, C-terminal zf-MYND PF01753.18 EAU83379.1 - 1.9e-09 37.5 10.8 4.1e-09 36.4 10.8 1.6 1 0 0 1 1 1 1 MYND finger NUDIX PF00293.28 EAU83380.2 - 6.2e-05 23.0 0.1 7.1e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DUF1653 PF07866.11 EAU83380.2 - 0.15 12.4 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) PHO4 PF01384.20 EAU83382.1 - 2.7e-108 362.0 16.9 3.2e-108 361.8 16.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF2474 PF10617.9 EAU83383.2 - 0.041 13.7 3.2 0.14 12.1 3.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) DUF4231 PF14015.6 EAU83383.2 - 0.16 12.5 2.7 0.97 9.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) COX7a PF02238.15 EAU83383.2 - 3.2 8.2 6.4 14 6.2 0.8 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII Ricin_B_lectin PF00652.22 EAU83384.2 - 4e-16 59.4 0.1 6.4e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU83384.2 - 1.6e-10 41.6 1.9 0.0012 19.6 1.6 3.2 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like F-box-like PF12937.7 EAU83385.2 - 1.3e-07 31.3 3.4 4.6e-07 29.6 3.4 2.0 1 1 0 1 1 1 1 F-box-like SKG6 PF08693.10 EAU83386.2 - 0.19 11.2 1.1 0.4 10.1 1.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EPL1 PF10513.9 EAU83387.1 - 0.27 11.6 11.5 0.55 10.6 3.7 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like E1_dh PF00676.20 EAU83388.1 - 7.8e-112 373.1 0.1 9.2e-112 372.8 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EAU83388.1 - 9.2e-05 21.8 0.0 0.00022 20.5 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EAU83388.1 - 0.00097 19.0 0.8 0.0017 18.1 0.8 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain F-box-like PF12937.7 EAU83389.2 - 8.5e-05 22.4 1.2 8.5e-05 22.4 1.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU83392.2 - 2.7e-06 27.2 0.4 6.8e-06 25.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.18 EAU83393.1 - 4.5e-11 42.6 5.7 4.5e-11 42.6 5.7 2.0 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.7 EAU83393.1 - 0.017 16.3 2.3 0.027 15.6 2.3 1.3 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-Mss51 PF13824.6 EAU83393.1 - 0.088 12.9 2.6 0.2 11.8 2.6 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 YjbE PF11106.8 EAU83394.1 - 2.4 8.4 17.3 0.5 10.6 13.1 2.0 1 1 1 2 2 2 0 Exopolysaccharide production protein YjbE HMG_box PF00505.19 EAU83395.2 - 5.5e-05 23.5 3.2 8e-05 23.0 2.5 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 EAU83395.2 - 0.0003 21.4 3.9 0.0003 21.4 3.9 2.0 1 1 0 2 2 2 1 YABBY protein zf-MYND PF01753.18 EAU83396.2 - 5.4e-11 42.4 6.8 1.2e-10 41.3 6.8 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EAU83396.2 - 0.014 15.5 2.7 0.04 14.0 2.7 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.7 EAU83396.2 - 0.024 15.8 1.2 0.042 15.0 1.2 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins F-box-like PF12937.7 EAU83397.2 - 3.7e-06 26.7 0.4 1.1e-05 25.2 0.4 1.8 1 0 0 1 1 1 1 F-box-like NmrA PF05368.13 EAU83398.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAU83398.1 - 0.00019 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAU83398.1 - 0.0032 16.9 0.0 0.0083 15.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Rrp40_N PF18311.1 EAU83398.1 - 0.15 12.0 0.1 0.86 9.6 0.0 2.2 2 0 0 2 2 2 0 Exosome complex exonuclease Rrp40 N-terminal domain NAD_binding_10 PF13460.6 EAU83399.1 - 2.8e-06 27.4 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAU83399.1 - 0.0002 21.0 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EAU83399.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Aldo_ket_red PF00248.21 EAU83400.2 - 3e-64 217.1 0.0 3.8e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TFIIF_beta PF02270.15 EAU83402.1 - 2e-28 98.3 0.3 3.2e-28 97.7 0.3 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EAU83402.1 - 1.3e-20 74.4 2.0 7.7e-20 72.0 2.0 2.2 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus DUF3591 PF12157.8 EAU83402.1 - 0.011 14.5 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) PhzC-PhzF PF02567.16 EAU83403.1 - 9e-25 87.7 0.0 1.5e-17 64.0 0.0 2.9 2 1 0 2 2 2 2 Phenazine biosynthesis-like protein CBF PF03914.17 EAU83418.2 - 6.9e-34 117.3 0.1 6.9e-34 117.3 0.1 3.3 3 1 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 EAU83418.2 - 0.033 14.2 0.1 0.087 12.9 0.0 1.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Gpi1 PF05024.15 EAU83419.2 - 3.7e-57 193.4 10.0 4.4e-57 193.2 9.2 1.5 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.22 EAU83420.1 - 6e-55 185.3 0.0 6.9e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU83420.1 - 1.7e-23 83.1 0.0 2.4e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU83420.1 - 9.6e-07 28.4 0.0 2e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAU83420.1 - 0.0032 16.8 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAU83420.1 - 0.0065 16.4 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EAU83420.1 - 0.14 12.5 0.0 0.42 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DAO PF01266.24 EAU83421.1 - 5e-34 118.4 0.1 6e-34 118.2 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU83421.1 - 0.034 14.4 0.1 0.1 12.8 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain CBP_BcsN PF17038.5 EAU83422.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN OPT PF03169.15 EAU83423.1 - 2e-190 634.5 60.6 2.3e-190 634.3 60.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SMC_N PF02463.19 EAU83424.2 - 1.7e-55 187.8 31.5 6.7e-55 185.9 31.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAU83424.2 - 1.6e-19 70.4 1.2 8.9e-19 67.9 0.1 2.6 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EAU83424.2 - 1.6e-13 51.6 11.8 1.6e-13 51.6 11.8 7.0 2 2 2 4 4 2 1 AAA domain AAA_21 PF13304.6 EAU83424.2 - 2.1e-11 44.2 6.1 6e-05 23.0 0.1 3.5 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EAU83424.2 - 3.5e-09 36.8 11.6 3.5e-09 36.8 11.6 4.3 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 EAU83424.2 - 3.3e-06 26.7 0.4 0.00016 21.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ERM PF00769.19 EAU83424.2 - 0.0054 16.6 11.0 0.0054 16.6 11.0 6.2 3 2 2 5 5 3 1 Ezrin/radixin/moesin family CLZ PF16526.5 EAU83424.2 - 0.014 15.7 3.7 0.014 15.7 3.7 10.5 6 4 5 11 11 11 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PhoU PF01895.19 EAU83424.2 - 0.022 15.2 1.5 0.022 15.2 1.5 5.5 5 1 0 5 5 5 0 PhoU domain ANAPC5 PF12862.7 EAU83424.2 - 0.079 13.0 2.9 0.61 10.2 0.1 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Fez1 PF06818.15 EAU83424.2 - 2.4 8.6 112.1 0.072 13.5 6.8 6.7 3 2 3 6 6 6 0 Fez1 RNase_H PF00075.24 EAU83425.2 - 0.0057 16.9 0.5 0.0057 16.9 0.5 2.9 3 1 0 3 3 3 1 RNase H DUF1524 PF07510.11 EAU83427.2 - 0.00012 22.0 0.0 0.00089 19.1 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1524) Cellulase PF00150.18 EAU83428.2 - 4.4e-31 108.3 3.8 7.3e-31 107.6 3.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_C12 PF01088.21 EAU83429.2 - 2e-47 161.7 0.0 2.8e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EAU83429.2 - 5.1e-06 26.3 0.1 5.1e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases TAF4 PF05236.14 EAU83429.2 - 0.038 13.8 0.6 0.059 13.1 0.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ASXH PF13919.6 EAU83430.1 - 5.5e-31 107.4 0.1 1.2e-30 106.4 0.1 1.6 2 0 0 2 2 2 1 Asx homology domain JmjC PF02373.22 EAU83432.2 - 1.3e-39 135.1 0.2 2.6e-39 134.2 0.2 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EAU83432.2 - 4.7e-15 55.3 0.4 1.1e-14 54.1 0.4 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 EAU83432.2 - 1.7e-13 50.6 0.7 4.6e-13 49.2 0.7 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EAU83432.2 - 1.2e-11 44.7 0.5 1.2e-11 44.7 0.5 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.29 EAU83432.2 - 0.027 14.3 3.1 0.075 12.9 3.1 1.8 1 0 0 1 1 1 0 PHD-finger CAP59_mtransfer PF11735.8 EAU83437.1 - 8.3e-37 127.1 0.0 1.5e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HAP1_N PF04849.13 EAU83439.2 - 0.0013 18.0 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region bZIP_1 PF00170.21 EAU83439.2 - 0.0025 17.9 1.0 0.0025 17.9 1.0 1.8 2 0 0 2 2 2 1 bZIP transcription factor ATG16 PF08614.11 EAU83439.2 - 0.0031 17.8 0.7 0.0037 17.5 0.7 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DivIC PF04977.15 EAU83439.2 - 0.0048 16.6 0.5 0.0075 16.0 0.1 1.5 2 0 0 2 2 2 1 Septum formation initiator ADIP PF11559.8 EAU83439.2 - 0.0059 16.7 0.2 0.01 15.9 0.2 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 EAU83439.2 - 0.017 15.5 0.7 0.017 15.5 0.7 1.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) KASH_CCD PF14662.6 EAU83439.2 - 0.017 14.9 0.6 0.025 14.4 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spc29 PF17082.5 EAU83439.2 - 0.038 13.9 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 ZapB PF06005.12 EAU83439.2 - 0.038 14.4 0.9 0.073 13.5 0.9 1.5 1 0 0 1 1 1 0 Cell division protein ZapB MAGSP PF03082.14 EAU83439.2 - 0.13 11.8 0.3 0.18 11.3 0.3 1.1 1 0 0 1 1 1 0 Male accessory gland secretory protein Spc7 PF08317.11 EAU83439.2 - 0.16 10.8 0.9 0.21 10.4 0.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Trypan_PARP PF05887.11 EAU83439.2 - 0.22 11.5 2.0 0.34 10.9 2.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YabA PF06156.13 EAU83439.2 - 0.24 12.0 0.2 0.24 12.0 0.2 1.4 2 0 0 2 2 1 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 EAU83439.2 - 0.25 11.6 1.9 0.28 11.5 0.2 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 EAU83439.2 - 2.1 8.4 5.6 0.34 10.9 0.7 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding F-box-like PF12937.7 EAU83441.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box-like NACHT PF05729.12 EAU83442.2 - 4.1e-07 30.1 0.0 9.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EAU83442.2 - 0.015 15.7 0.0 0.054 13.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU83442.2 - 0.035 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Cys_Met_Meta_PP PF01053.20 EAU83443.2 - 3.2e-134 447.3 0.0 3.9e-134 447.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EAU83443.2 - 2.7e-12 46.7 0.4 9.4e-12 44.9 0.3 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EAU83443.2 - 1.8e-09 37.3 0.1 2.8e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EAU83443.2 - 4.9e-09 35.6 0.7 9.5e-09 34.7 0.7 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EAU83443.2 - 2.4e-05 23.8 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EAU83443.2 - 0.0067 15.0 0.1 0.0096 14.5 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 EAU83443.2 - 0.02 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein F-box-like PF12937.7 EAU83444.1 - 1.3e-07 31.4 1.9 3.4e-07 30.0 1.9 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU83444.1 - 1.6 8.7 4.9 0.44 10.5 0.3 2.4 2 0 0 2 2 2 0 F-box domain Glyco_hydro_cc PF11790.8 EAU83450.1 - 2e-68 230.5 4.7 2.4e-68 230.3 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.17 EAU83450.1 - 0.045 12.3 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 MMR_HSR1 PF01926.23 EAU83452.2 - 4.8e-14 52.4 0.2 8.2e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU83452.2 - 0.0015 18.1 0.1 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAU83452.2 - 0.0032 17.5 1.9 1.3 9.0 0.1 3.2 4 0 0 4 4 4 2 Dynamin family RsgA_GTPase PF03193.16 EAU83452.2 - 0.016 15.1 0.4 0.12 12.3 0.4 2.3 1 1 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 EAU83452.2 - 0.089 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 EAU83452.2 - 0.11 11.9 0.1 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 EAU83452.2 - 0.12 12.9 0.2 0.52 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAU83452.2 - 0.18 11.5 0.0 7.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pkinase_Tyr PF07714.17 EAU83453.2 - 7.2e-36 123.8 0.0 8.5e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU83453.2 - 6.5e-35 120.8 0.0 8.2e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAU83453.2 - 0.0024 17.3 0.0 0.0051 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU83453.2 - 0.003 17.5 0.0 0.008 16.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU83453.2 - 0.024 13.9 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EAU83453.2 - 0.034 13.1 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EAU83453.2 - 0.13 11.3 0.0 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.22 EAU83453.2 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Gti1_Pac2 PF09729.9 EAU83455.1 - 4.5e-56 189.8 0.3 4.5e-56 189.8 0.3 3.2 2 2 0 2 2 2 1 Gti1/Pac2 family WSC PF01822.19 EAU83456.1 - 7.7e-66 218.3 52.1 6.2e-18 64.8 8.9 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 EAU83456.1 - 1.1e-25 90.2 0.0 2.8e-25 88.9 0.0 1.7 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EAU83456.1 - 4e-23 81.5 0.0 9.2e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 EAU83456.1 - 0.025 14.9 2.2 1.2 9.5 0.0 4.1 4 1 1 5 5 5 0 Kelch motif Glyco_trans_2_3 PF13632.6 EAU83457.1 - 1.8e-58 197.7 0.5 1.8e-58 197.7 0.5 3.3 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAU83457.1 - 1.5e-05 25.0 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EAU83457.1 - 0.00079 19.3 0.1 0.0071 16.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAU83457.1 - 0.19 11.2 0.0 0.78 9.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 EAU83458.2 - 1.6e-21 76.6 0.1 2.8e-21 75.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ras PF00071.22 EAU83465.2 - 1.4e-53 180.9 0.1 1.6e-53 180.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU83465.2 - 3.6e-32 111.1 0.0 6.5e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU83465.2 - 2.7e-13 49.7 0.0 3.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAU83465.2 - 2.8e-06 26.8 0.0 3.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU83465.2 - 2.9e-06 27.4 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAU83465.2 - 0.0015 19.0 0.0 0.0029 18.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 EAU83465.2 - 0.0022 17.6 0.3 0.027 14.0 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EAU83465.2 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EAU83465.2 - 0.023 14.0 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 EAU83465.2 - 0.031 14.0 0.0 0.062 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EAU83465.2 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF2119 PF09892.9 EAU83465.2 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) G-alpha PF00503.20 EAU83465.2 - 0.12 11.5 1.5 3.6 6.6 0.3 2.2 1 1 1 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 EAU83465.2 - 0.19 11.6 0.2 0.68 9.8 0.1 1.8 1 1 0 2 2 2 0 RsgA GTPase Questin_oxidase PF14027.6 EAU83469.2 - 2.2e-70 237.9 0.0 7.5e-66 223.0 0.0 2.1 1 1 1 2 2 2 2 Questin oxidase-like AT_hook PF02178.19 EAU83472.2 - 0.031 14.1 3.0 0.031 14.1 3.0 3.4 3 0 0 3 3 3 0 AT hook motif DUF4611 PF15387.6 EAU83472.2 - 0.085 13.1 6.2 1 9.6 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EAU83472.2 - 0.63 10.5 5.4 6.3 7.3 0.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peroxin-3 PF04882.12 EAU83472.2 - 0.83 8.6 3.4 1.3 7.9 3.4 1.2 1 0 0 1 1 1 0 Peroxin-3 AhpC-TSA PF00578.21 EAU83474.2 - 4.1e-30 104.3 0.0 1e-29 102.9 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EAU83474.2 - 3.5e-12 45.9 0.0 6.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EAU83474.2 - 1.6e-10 40.9 0.0 4.2e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 Redoxin Presenilin PF01080.17 EAU83477.1 - 4.2 6.0 9.6 9 4.9 9.6 1.5 1 0 0 1 1 1 0 Presenilin cEGF PF12662.7 EAU83478.1 - 0.16 12.0 0.7 0.16 12.0 0.7 4.9 5 0 0 5 5 5 0 Complement Clr-like EGF-like YiaAB PF05360.14 EAU83478.1 - 0.73 10.1 2.8 1.2 9.4 2.8 1.3 1 0 0 1 1 1 0 yiaA/B two helix domain F-box-like PF12937.7 EAU83479.2 - 4.4e-06 26.5 0.2 1.2e-05 25.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like Xan_ur_permease PF00860.20 EAU83480.2 - 3.6e-28 98.4 30.2 2.1e-26 92.5 30.2 2.7 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EAU83480.2 - 0.0016 18.8 3.5 0.0016 18.8 3.5 3.0 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 EAU83480.2 - 0.68 9.6 4.8 0.18 11.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) F-box-like PF12937.7 EAU83481.2 - 4.5e-05 23.3 0.1 0.0001 22.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like Baculo_LEF-11 PF06385.12 EAU83481.2 - 0.048 14.1 0.0 2.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Baculovirus LEF-11 protein PS_Dcarbxylase PF02666.15 EAU83481.2 - 0.22 11.0 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase FA_hydroxylase PF04116.13 EAU83482.1 - 3e-24 85.9 20.5 3e-24 85.9 20.5 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ntox1 PF15500.6 EAU83482.1 - 0.048 14.0 1.3 0.079 13.3 1.3 1.2 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 DUF89 PF01937.19 EAU83482.1 - 0.093 11.7 0.5 0.54 9.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF89 TFIIB PF00382.19 EAU83484.1 - 7.3e-33 112.4 0.0 2.3e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EAU83484.1 - 1e-14 53.8 1.1 1.6e-14 53.1 1.1 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.6 EAU83484.1 - 0.00076 18.8 1.3 0.18 11.2 0.0 3.9 5 0 0 5 5 5 1 Helix-turn-helix domain of transposase family ISL3 RB_B PF01857.20 EAU83484.1 - 0.0084 16.1 0.1 0.058 13.4 0.0 2.1 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Cyclin_N PF00134.23 EAU83484.1 - 0.014 15.1 0.2 0.026 14.3 0.2 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain zinc_ribbon_10 PF10058.9 EAU83484.1 - 0.019 14.6 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 EAU83484.1 - 0.045 13.2 1.8 0.52 9.8 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HTH_28 PF13518.6 EAU83484.1 - 0.058 13.5 0.1 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Pkinase_Tyr PF07714.17 EAU83485.2 - 2.7e-32 112.1 0.0 4e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU83485.2 - 3.1e-31 108.7 0.0 4.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU83485.2 - 0.038 13.9 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.7 EAU83486.1 - 2.3e-07 30.6 1.0 2.3e-07 30.6 1.0 2.2 3 0 0 3 3 3 1 F-box-like Tubulin PF00091.25 EAU83487.1 - 1.3e-68 231.0 0.0 2.9e-68 230.0 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAU83487.1 - 1.7e-42 144.6 0.1 2.7e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EAU83487.1 - 6.5e-06 26.4 0.0 1.9e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EAU83487.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EAU83487.1 - 0.0025 17.1 0.0 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Tubulin like CBFD_NFYB_HMF PF00808.23 EAU83488.1 - 1.3e-16 60.6 1.1 3.1e-16 59.4 1.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU83488.1 - 0.00051 20.4 0.2 0.00051 20.4 0.2 2.4 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EAU83488.1 - 0.02 15.0 1.1 0.041 14.0 1.1 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF778 PF05608.12 EAU83488.1 - 0.055 13.8 0.6 0.063 13.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF5427 PF10310.9 EAU83488.1 - 0.1 11.6 8.0 0.12 11.3 8.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLD5_C PF16922.5 EAU83489.1 - 1.2e-09 38.2 0.0 3.2e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EAU83489.1 - 0.00041 20.8 0.5 0.00089 19.7 0.5 1.7 1 1 0 1 1 1 1 GINS complex protein DUF4692 PF15763.5 EAU83490.1 - 1.6 9.2 6.1 0.27 11.7 0.1 2.3 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) NACHT PF05729.12 EAU83491.2 - 6.1e-11 42.5 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83491.2 - 1.2e-06 29.1 0.1 3.3e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAU83491.2 - 0.00051 20.5 0.0 0.0019 18.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAU83491.2 - 0.042 13.6 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EAU83491.2 - 0.09 11.8 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.15 EAU83491.2 - 0.12 12.3 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EAU83491.2 - 0.2 11.7 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peptidase_M48_N PF16491.5 EAU83492.1 - 2.2e-60 203.7 7.2 2.2e-60 203.7 7.2 2.2 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EAU83492.1 - 1.8e-34 119.2 0.1 3.5e-33 115.0 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M48 p450 PF00067.22 EAU83493.2 - 3.7e-66 223.8 0.0 8e-66 222.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ATG22 PF11700.8 EAU83494.2 - 4.7e-124 414.6 4.5 1.2e-70 238.5 0.0 2.8 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like F-box-like PF12937.7 EAU83495.2 - 6.9e-07 29.1 0.7 6.9e-07 29.1 0.7 1.8 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU83496.1 - 4.3e-07 29.7 1.9 8.6e-07 28.8 1.9 1.5 1 0 0 1 1 1 1 F-box-like Osmo_CC PF08946.10 EAU83496.1 - 0.021 15.0 0.2 0.054 13.8 0.2 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF3450 PF11932.8 EAU83496.1 - 0.04 13.2 0.7 0.08 12.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) F-box PF00646.33 EAU83496.1 - 0.43 10.5 1.8 6.4 6.8 1.8 2.4 1 1 0 1 1 1 0 F-box domain Spc7 PF08317.11 EAU83496.1 - 1.2 8.0 3.2 14 4.5 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein F-box-like PF12937.7 EAU83497.1 - 1.8e-06 27.7 0.9 8.7e-06 25.5 0.3 2.6 2 1 0 2 2 2 1 F-box-like Hydrophobin PF01185.18 EAU83498.1 - 6.2e-13 49.2 7.7 7.5e-13 48.9 7.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF3433 PF11915.8 EAU83499.2 - 4.9e-18 65.4 1.2 1.2e-17 64.1 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) OPT PF03169.15 EAU83499.2 - 0.074 11.7 2.5 0.82 8.2 0.4 2.1 2 0 0 2 2 2 0 OPT oligopeptide transporter protein EamA PF00892.20 EAU83500.1 - 1.2e-26 93.5 25.9 1.1e-13 51.5 5.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EAU83500.1 - 0.027 13.7 8.1 0.028 13.7 3.6 2.6 2 1 0 2 2 2 0 Purine nucleobase transmembrane transport TspO_MBR PF03073.15 EAU83500.1 - 7.1 6.7 10.2 0.19 11.8 2.7 2.1 2 1 0 2 2 2 0 TspO/MBR family zf-C2H2_aberr PF17017.5 EAU83502.2 - 0.036 14.2 6.5 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2 PF00096.26 EAU83502.2 - 0.17 12.4 13.2 0.068 13.7 1.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU83502.2 - 3.7 8.6 15.6 3 8.9 0.7 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger EamA PF00892.20 EAU83503.2 - 1.1e-28 100.1 37.0 1.7e-16 60.7 11.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family Gemini_AC4_5_2 PF08464.10 EAU83503.2 - 0.085 12.8 0.4 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region DUF2637 PF10935.8 EAU83503.2 - 1.9 8.4 8.6 1.7 8.5 3.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2637) OCD_Mu_crystall PF02423.15 EAU83505.1 - 1.7e-18 66.6 1.4 1.1e-08 34.4 0.0 3.3 3 0 0 3 3 3 3 Ornithine cyclodeaminase/mu-crystallin family THF_DHG_CYH_C PF02882.19 EAU83505.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 EAU83505.1 - 0.0044 17.1 0.0 0.046 13.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EAU83506.2 - 1.7e-29 103.0 0.0 3.3e-16 59.2 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EAU83506.2 - 1e-11 44.7 0.0 2.3e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAU83506.2 - 5.3e-06 25.9 0.0 9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU83506.2 - 9.4e-05 22.6 1.5 0.00012 22.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU83506.2 - 0.00011 21.9 1.2 0.0042 16.7 0.2 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EAU83506.2 - 0.00011 21.7 0.2 0.00043 19.8 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAU83506.2 - 0.00046 19.0 0.0 0.00082 18.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EAU83506.2 - 0.0011 19.5 0.1 0.023 15.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU83506.2 - 0.0068 15.7 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EAU83506.2 - 0.0084 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EAU83506.2 - 0.011 15.0 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU83506.2 - 0.013 14.6 0.1 0.027 13.5 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 EAU83506.2 - 0.016 15.7 0.1 0.14 12.6 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EAU83506.2 - 0.023 14.6 0.5 0.37 10.7 0.1 2.4 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EAU83506.2 - 0.17 10.9 0.0 0.41 9.6 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EAU83507.1 - 3.1e-31 108.7 0.0 2.8e-16 59.4 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EAU83507.1 - 3.3e-18 66.1 0.0 3.7e-14 52.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EAU83507.1 - 1.8e-07 30.9 0.0 4.5e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU83507.1 - 1.5e-05 24.4 0.0 2.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU83507.1 - 3.4e-05 22.7 0.0 0.00014 20.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EAU83507.1 - 4.1e-05 23.7 0.7 0.00011 22.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EAU83507.1 - 0.00015 21.0 0.1 0.0016 17.6 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EAU83507.1 - 0.00017 20.9 0.1 0.00056 19.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EAU83507.1 - 0.00046 19.9 0.1 0.014 15.0 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAU83507.1 - 0.0075 16.8 0.2 0.051 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU83507.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EAU83507.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EAU83507.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_D2 PF02786.17 EAU83508.2 - 5e-104 346.4 0.3 2.2e-70 236.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EAU83508.2 - 1e-48 164.3 0.0 2.8e-48 163.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EAU83508.2 - 2e-47 161.4 0.0 8.9e-46 156.1 0.0 2.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EAU83508.2 - 2.9e-46 157.1 0.0 6.2e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EAU83508.2 - 1.9e-39 134.7 0.2 7e-39 133.0 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EAU83508.2 - 1.9e-31 109.2 0.0 5.4e-31 107.8 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EAU83508.2 - 1.2e-19 70.2 0.0 6.1e-19 68.0 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EAU83508.2 - 1.3e-17 64.0 0.3 1.1e-09 38.1 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EAU83508.2 - 3.2e-17 62.6 0.5 5.1e-08 32.7 0.1 2.7 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 EAU83508.2 - 2.5e-06 27.4 0.0 0.00039 20.2 0.0 2.8 2 0 0 2 2 2 1 Peptidase C26 ATPgrasp_Ter PF15632.6 EAU83508.2 - 6.2e-05 22.7 0.0 0.00036 20.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 EAU83508.2 - 0.00023 20.8 0.0 0.27 10.8 0.1 2.7 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EAU83508.2 - 0.0034 17.4 0.1 0.011 15.8 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EAU83508.2 - 0.0034 17.2 0.1 0.31 10.8 0.0 2.5 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 EAU83508.2 - 0.0062 16.0 0.0 1.1 8.7 0.1 2.5 2 0 0 2 2 2 1 ATP-grasp domain DJ-1_PfpI PF01965.24 EAU83508.2 - 0.0077 16.0 0.0 4.4 7.1 0.0 4.6 5 0 0 5 5 5 1 DJ-1/PfpI family Isochorismatase PF00857.20 EAU83508.2 - 0.078 13.1 0.0 7.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Isochorismatase family Cyt-b5 PF00173.28 EAU83509.1 - 1.3e-12 47.7 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2236 PF09995.9 EAU83510.2 - 5.6e-09 36.5 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Imm61 PF15598.6 EAU83510.2 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 61 TAFII28 PF04719.14 EAU83511.2 - 4.2e-34 116.5 0.1 6.4e-34 115.9 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 EAU83511.2 - 0.0044 17.3 0.0 0.0067 16.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hydantoinase_A PF01968.18 EAU83511.2 - 0.16 11.2 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase AAA_16 PF13191.6 EAU83514.2 - 0.00044 20.7 0.0 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU83514.2 - 0.0054 17.0 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAU83514.2 - 0.064 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EAU83514.2 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EAU83514.2 - 0.18 11.3 0.0 0.75 9.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region SpoVAE PF14097.6 EAU83515.1 - 0.016 14.9 0.8 0.022 14.4 0.8 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Ribosomal_L27 PF01016.19 EAU83515.1 - 0.072 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L27 protein IER PF05760.12 EAU83515.1 - 2 8.6 7.5 2 8.7 6.5 1.4 1 1 0 1 1 1 0 Immediate early response protein (IER) Sugar_tr PF00083.24 EAU83517.1 - 9.5e-126 420.3 10.5 1.1e-125 420.1 10.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU83517.1 - 1.6e-17 63.5 31.1 1.9e-12 46.8 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 EAU83519.2 - 0.0019 18.0 0.0 0.0054 16.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU83519.2 - 0.078 12.9 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 EAU83522.1 - 7.2e-07 29.0 0.7 2.7e-06 27.2 0.5 2.2 2 0 0 2 2 2 1 F-box-like DUF992 PF06186.11 EAU83522.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) NACHT PF05729.12 EAU83523.2 - 2.5e-09 37.3 0.0 4.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83523.2 - 3.7e-06 27.4 0.0 8.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU83523.2 - 0.0031 17.8 0.0 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain zf-MYND PF01753.18 EAU83524.2 - 2.3e-11 43.6 6.1 4.2e-11 42.8 6.1 1.4 1 0 0 1 1 1 1 MYND finger SET PF00856.28 EAU83524.2 - 1.8e-07 31.7 0.0 4.4e-07 30.5 0.0 1.7 2 1 0 2 2 2 1 SET domain zf-C6H2 PF15801.5 EAU83524.2 - 2.2 8.6 6.4 4.4 7.7 6.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Prenyltrans PF00432.21 EAU83525.1 - 3.5e-60 199.4 6.0 4.2e-11 42.4 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EAU83525.1 - 0.00057 19.1 0.0 0.002 17.3 0.0 1.7 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EAU83525.1 - 0.00074 18.7 0.0 0.17 10.9 0.0 3.5 2 1 2 4 4 4 1 Squalene-hopene cyclase N-terminal domain zf-CSL PF05207.13 EAU83526.1 - 1.1e-21 76.3 0.8 1.1e-21 76.3 0.8 1.7 2 0 0 2 2 2 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EAU83526.1 - 0.0056 16.8 1.0 0.011 15.8 1.0 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 EAU83526.1 - 0.0065 15.1 0.4 0.0083 14.7 0.4 1.2 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) BUD22 PF09073.10 EAU83526.1 - 0.011 15.1 3.4 0.011 15.1 3.4 1.0 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 EAU83526.1 - 0.013 15.4 5.5 0.013 15.4 5.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 EAU83526.1 - 0.056 13.1 1.9 0.073 12.7 1.9 1.2 1 0 0 1 1 1 0 FAM176 family DUF688 PF05097.12 EAU83526.1 - 0.077 12.1 1.1 0.085 12.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) CDC45 PF02724.14 EAU83526.1 - 1.4 7.1 5.4 1.4 7.1 5.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EAU83526.1 - 4.4 5.7 6.4 4.8 5.6 6.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EAU83526.1 - 5.6 5.0 10.7 6.6 4.8 10.7 1.0 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.7 EAU83528.1 - 4.7e-05 23.2 1.1 0.00011 22.1 1.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU83528.1 - 0.42 11.1 7.7 8.8 6.9 0.1 4.9 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Mito_carr PF00153.27 EAU83529.1 - 1.7e-17 63.1 6.9 2.6e-07 30.5 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box PF00646.33 EAU83530.2 - 0.00067 19.5 0.2 0.0039 17.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAU83530.2 - 0.013 15.3 0.8 0.18 11.8 0.3 2.6 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EAU83531.2 - 0.00018 21.3 1.2 0.0042 16.9 0.0 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EAU83531.2 - 0.0067 16.3 0.0 0.061 13.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like Piwi PF02171.17 EAU83532.1 - 1.9e-76 257.2 0.0 2.7e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EAU83532.1 - 4.3e-19 69.5 0.1 1.1e-18 68.2 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EAU83532.1 - 3.5e-12 46.5 0.0 1.2e-11 44.8 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EAU83532.1 - 1.8e-11 44.0 0.0 3.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EAU83532.1 - 4.9e-11 42.1 0.2 1.7e-10 40.4 0.1 2.0 2 0 0 2 2 2 1 Argonaute linker 1 domain NACHT PF05729.12 EAU83537.2 - 0.00018 21.5 0.0 0.00035 20.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83537.2 - 0.0016 18.9 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAU83537.2 - 0.046 13.4 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_M1 PF01433.20 EAU83538.2 - 2.6e-37 128.5 0.1 3.5e-37 128.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EAU83538.2 - 2.4e-28 98.5 0.0 6e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EAU83538.2 - 9.9e-15 55.2 0.0 1.7e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EAU83538.2 - 0.36 11.2 4.0 11 6.5 4.1 2.5 1 1 0 1 1 1 0 M61 glycyl aminopeptidase TPR_1 PF00515.28 EAU83539.1 - 4e-41 137.2 12.6 6.5e-06 25.7 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 EAU83539.1 - 2.4e-39 130.3 12.8 2.3e-05 24.2 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 EAU83539.1 - 5.6e-23 79.2 10.3 0.0057 16.8 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAU83539.1 - 1.5e-21 75.8 15.7 1.9e-06 27.4 0.0 9.0 5 2 3 9 9 9 6 TPR repeat TPR_17 PF13431.6 EAU83539.1 - 4.5e-21 73.6 2.9 6.8e-05 23.0 0.0 8.8 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAU83539.1 - 8.7e-20 71.0 11.2 0.00015 22.2 0.9 7.2 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAU83539.1 - 1.4e-19 70.5 12.6 1e-05 26.1 0.0 6.9 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAU83539.1 - 4.1e-17 62.2 15.9 2.3e-05 24.6 0.0 7.8 5 2 4 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAU83539.1 - 4e-15 54.6 3.7 0.2 11.7 0.0 8.2 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAU83539.1 - 4.6e-15 55.5 1.3 0.0029 17.7 0.0 5.8 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAU83539.1 - 5.9e-15 54.7 14.9 6e-05 23.5 0.0 9.3 6 4 4 10 10 10 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAU83539.1 - 8.8e-08 32.3 10.9 0.31 11.8 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU83539.1 - 4.2e-07 30.1 11.0 0.03 14.5 0.0 5.2 4 3 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EAU83539.1 - 4.7e-07 29.5 0.8 0.0014 18.1 2.5 3.1 2 1 1 3 3 3 2 MalT-like TPR region TPR_15 PF13429.6 EAU83539.1 - 8.8e-06 25.1 4.7 0.063 12.5 0.0 4.2 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EAU83539.1 - 4.6e-05 23.7 13.2 9.6 6.6 0.0 6.5 4 2 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU83539.1 - 0.00031 20.5 10.7 4 7.4 0.3 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF3856 PF12968.7 EAU83539.1 - 0.00041 20.4 5.8 0.22 11.6 0.0 5.1 4 2 2 6 6 5 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 EAU83539.1 - 0.0011 18.0 0.1 0.0011 18.0 0.1 3.7 2 2 1 4 4 4 1 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.9 EAU83539.1 - 0.0015 17.9 5.2 26 4.4 0.1 5.1 5 0 0 5 5 5 0 SHNi-TPR DUF627 PF04781.12 EAU83539.1 - 0.014 15.4 1.4 0.069 13.2 0.0 3.1 4 0 0 4 4 3 0 Protein of unknown function (DUF627) Sel1 PF08238.12 EAU83539.1 - 0.021 15.5 0.1 17 6.3 0.0 3.7 2 0 0 2 2 2 0 Sel1 repeat Prolamin_like PF05617.11 EAU83539.1 - 0.051 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Prolamin-like MAS20 PF02064.15 EAU83539.1 - 0.058 13.5 15.2 2.2 8.4 4.9 5.1 4 2 1 5 5 5 0 MAS20 protein import receptor MIT PF04212.18 EAU83539.1 - 0.22 11.6 17.8 2.5 8.2 0.2 6.6 7 1 1 8 8 6 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EAU83539.1 - 0.5 10.8 6.7 2.8 8.3 0.0 4.1 3 1 2 5 5 4 0 Bacterial transcriptional activator domain ANAPC5 PF12862.7 EAU83539.1 - 4.4 7.4 7.5 13 5.9 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 EOS1 PF12326.8 EAU83540.2 - 9.4e-38 129.9 1.0 9.4e-38 129.9 1.0 2.7 3 1 0 3 3 3 1 N-glycosylation protein p450 PF00067.22 EAU83541.2 - 2.6e-33 115.5 0.0 3.2e-16 59.2 0.1 3.0 2 1 1 3 3 3 3 Cytochrome P450 L_biotic_typeA PF04604.13 EAU83541.2 - 0.13 12.1 0.1 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Type-A lantibiotic KCH PF16944.5 EAU83542.2 - 0.0075 16.1 2.9 0.011 15.5 2.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel CBM_1 PF00734.18 EAU83544.2 - 5.2e-14 51.9 10.7 1.6e-13 50.4 10.7 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain PhoPQ_related PF10142.9 EAU83544.2 - 0.043 12.5 0.1 0.064 11.9 0.1 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Toxin_7 PF05980.12 EAU83544.2 - 0.72 10.1 11.8 0.37 11.1 8.9 2.0 2 0 0 2 2 2 0 Toxin 7 F-box-like PF12937.7 EAU83545.2 - 3.7e-08 33.1 0.4 9.2e-08 31.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like Siah-Interact_N PF09032.11 EAU83545.2 - 1.2 9.5 4.5 1.5 9.2 1.2 2.6 3 0 0 3 3 3 0 Siah interacting protein, N terminal Pkinase PF00069.25 EAU83547.2 - 8.1e-20 71.3 0.0 1.7e-15 57.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU83547.2 - 3.9e-07 29.6 0.0 4.3e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU83547.2 - 0.00013 20.8 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase UvrB PF12344.8 EAU83547.2 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Ultra-violet resistance protein B Glycos_transf_1 PF00534.20 EAU83548.2 - 2.2e-24 85.9 0.0 8.4e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAU83548.2 - 1.8e-20 73.6 0.1 3.8e-20 72.6 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EAU83548.2 - 8.8e-12 45.6 0.0 8.3e-11 42.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EAU83548.2 - 4.5e-11 43.4 0.0 2.5e-09 37.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EAU83548.2 - 0.002 18.5 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 2OG-FeII_Oxy_2 PF13532.6 EAU83551.1 - 5.5e-26 92.0 0.0 7.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EAU83551.1 - 0.1 13.1 0.0 0.32 11.5 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Rad60-SLD PF11976.8 EAU83554.1 - 7.9e-24 83.3 0.1 1e-23 82.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAU83554.1 - 2.2e-13 49.7 0.1 2.7e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF5010_C PF18099.1 EAU83554.1 - 0.0073 16.4 0.1 0.0084 16.2 0.1 1.0 1 0 0 1 1 1 1 DUF5010 C-terminal domain NACHT PF05729.12 EAU83555.2 - 5.2e-07 29.7 0.0 1.6e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EAU83555.2 - 2.8e-06 27.8 0.0 7.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU83555.2 - 0.075 13.3 0.0 0.35 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EAU83555.2 - 0.11 13.0 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EAU83555.2 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Helitron_like_N PF14214.6 EAU83557.2 - 1.3e-31 110.3 0.0 3e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAU83557.2 - 1.1e-26 93.9 0.0 2.4e-25 89.5 0.0 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU83557.2 - 2.9e-10 40.2 0.0 9.3e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU83557.2 - 7.9e-06 26.3 0.0 2e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAU83557.2 - 0.0023 18.2 1.0 0.014 15.7 0.2 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAU83557.2 - 0.0046 16.2 0.1 0.0095 15.1 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.18 EAU83557.2 - 0.0067 16.2 0.3 1.3 8.7 0.2 3.4 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EAU83557.2 - 0.011 16.1 0.2 0.049 14.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EAU83557.2 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAU83557.2 - 0.064 13.2 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 EAU83557.2 - 0.083 12.9 0.2 32 4.5 0.0 3.5 2 1 0 2 2 2 0 AAA domain F-box-like PF12937.7 EAU83558.2 - 6.3e-10 38.8 2.0 1.8e-08 34.1 0.3 2.6 2 0 0 2 2 2 2 F-box-like LRR_2 PF07723.13 EAU83558.2 - 0.54 11.0 4.2 0.83 10.4 1.6 2.7 2 0 0 2 2 2 0 Leucine Rich Repeat Helitron_like_N PF14214.6 EAU83563.2 - 4.8e-33 115.0 0.1 1.1e-32 113.8 0.1 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAU83563.2 - 6.8e-24 84.7 0.0 1.3e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU83563.2 - 1.4e-11 44.4 0.0 3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU83563.2 - 3.4e-07 30.7 0.0 9.8e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RicinB_lectin_2 PF14200.6 EAU83564.2 - 2e-20 73.3 7.8 4.8e-12 46.5 0.4 3.0 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Sec7_N PF12783.7 EAU83566.2 - 1.7e-53 180.7 0.6 1.7e-53 180.7 0.6 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EAU83566.2 - 1.2e-36 126.0 2.7 1.7e-36 125.5 1.5 2.0 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EAU83566.2 - 9.7e-31 106.7 0.0 2.1e-15 56.0 0.0 3.6 2 2 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 EAU83566.2 - 0.00053 19.8 0.0 0.0081 16.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 EAU83566.2 - 0.019 15.1 0.0 0.37 11.0 0.0 3.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Glyco_transf_15 PF01793.16 EAU83567.1 - 3.1e-122 407.9 8.1 3.7e-122 407.6 8.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GTA_holin_3TM PF11351.8 EAU83567.1 - 0.13 12.8 0.1 0.24 11.9 0.1 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release GASA PF02704.14 EAU83568.1 - 0.0041 17.2 1.4 0.0075 16.4 1.4 1.4 1 0 0 1 1 1 1 Gibberellin regulated protein DUF3246 PF11596.8 EAU83568.1 - 0.42 10.0 16.2 0.58 9.6 16.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Hamartin PF04388.12 EAU83572.1 - 1 7.9 3.1 1 7.9 3.1 1.1 1 0 0 1 1 1 0 Hamartin protein adh_short PF00106.25 EAU83574.2 - 3.2e-26 92.0 0.0 4.1e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU83574.2 - 1.4e-21 77.2 0.1 1.8e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 EAU83574.2 - 9.8e-05 22.3 2.5 0.00023 21.1 0.2 2.2 2 1 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.18 EAU83574.2 - 0.02 14.8 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_3 PF13920.6 EAU83575.2 - 0.0061 16.4 0.5 0.011 15.6 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU83575.2 - 0.0074 16.1 1.6 0.012 15.5 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU83575.2 - 0.072 13.4 1.6 0.13 12.6 1.6 1.4 1 0 0 1 1 1 0 Ring finger domain Homeodomain PF00046.29 EAU83576.2 - 8.4e-15 54.4 1.1 1.7e-14 53.4 1.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EAU83576.2 - 0.053 13.4 2.3 0.075 13.0 0.1 2.4 2 0 0 2 2 2 0 Homeobox KN domain Bromodomain PF00439.25 EAU83578.1 - 9.4e-20 70.5 0.0 1.9e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain G5 PF07501.12 EAU83579.2 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 G5 domain PLDc PF00614.22 EAU83580.1 - 2.4e-12 46.5 2.7 2.1e-07 30.8 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EAU83580.1 - 2.4e-11 43.6 0.1 5.1e-07 29.6 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Nup84_Nup100 PF04121.13 EAU83582.2 - 1.6e-169 565.4 0.0 1.9e-169 565.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.14 EAU83582.2 - 0.032 12.7 0.1 0.056 11.9 0.1 1.3 1 0 0 1 1 1 0 Nup93/Nic96 Defensin_3 PF08131.11 EAU83583.2 - 0.035 14.3 2.4 0.17 12.1 2.4 2.2 2 1 0 2 2 2 0 Defensin-like peptide family Complex1_49kDa PF00346.19 EAU83583.2 - 0.13 11.3 0.1 0.19 10.8 0.1 1.3 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Cellulase PF00150.18 EAU83584.1 - 1.1e-11 44.7 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ThrE PF06738.12 EAU83585.2 - 5.3e-54 183.1 7.2 5.3e-54 183.1 7.2 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EAU83585.2 - 4.4e-10 39.8 29.7 2e-09 37.7 6.7 2.2 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Glyco_transf_15 PF01793.16 EAU83586.1 - 8.4e-125 416.3 10.5 1e-124 416.0 10.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PIP5K PF01504.18 EAU83589.2 - 1.9e-49 168.4 0.1 1.4e-40 139.3 0.1 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Pro_isomerase PF00160.21 EAU83590.2 - 9.8e-31 107.2 0.1 1.5e-30 106.5 0.1 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GMC_oxred_N PF00732.19 EAU83591.2 - 1.2e-59 202.1 0.0 1.8e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU83591.2 - 1.7e-33 116.2 0.0 3.5e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EAU83591.2 - 2.4e-06 26.9 0.1 3.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EAU83591.2 - 0.00052 19.3 0.0 0.0019 17.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EAU83591.2 - 0.0008 18.6 0.0 0.13 11.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 EAU83591.2 - 0.015 14.4 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EAU83591.2 - 0.048 12.9 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU83591.2 - 0.11 11.2 0.5 0.17 10.5 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein FGGY_N PF00370.21 EAU83592.1 - 0.043 13.4 0.0 6 6.3 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain DIM1 PF02966.16 EAU83593.2 - 3.8e-68 227.4 0.1 4.2e-68 227.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EAU83593.2 - 5.3e-05 23.1 0.0 6.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EAU83593.2 - 0.012 16.0 0.2 0.019 15.3 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like SNF2_N PF00176.23 EAU83594.1 - 2.3e-64 217.3 0.1 1e-63 215.2 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU83594.1 - 3.2e-17 62.9 0.0 9.3e-16 58.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU83594.1 - 1.8e-09 37.8 0.0 9.7e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAU83594.1 - 0.0083 15.9 0.0 0.82 9.4 0.0 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase PAP_assoc PF03828.19 EAU83595.2 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EAU83595.2 - 6.6e-07 29.5 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EAU83595.2 - 0.012 15.7 0.1 0.044 13.9 0.0 2.0 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 EAU83596.2 - 2.2e-06 27.8 0.0 4.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EAU83596.2 - 8.8e-06 25.9 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain MutL_C PF08676.11 EAU83597.2 - 7.3e-17 61.5 0.1 1.7e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EAU83597.2 - 8.3e-15 54.5 0.0 9.1e-08 31.8 0.0 2.4 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EAU83597.2 - 1.6e-14 53.9 0.2 3.5e-14 52.8 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EAU83597.2 - 4.1e-08 33.7 0.2 1.1e-07 32.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase G-alpha PF00503.20 EAU83598.2 - 4.8e-76 256.2 0.0 4.8e-72 243.1 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 EAU83598.2 - 4e-08 32.9 0.3 1.1e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Pyr_redox_2 PF07992.14 EAU83599.2 - 8.9e-17 61.3 0.0 1.2e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU83599.2 - 1.1e-06 29.0 2.4 1.2e-05 25.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2347 PF09804.9 EAU83600.2 - 1.2e-32 113.6 0.0 6.5e-32 111.3 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 EAU83600.2 - 5.2e-08 32.0 0.0 0.014 14.1 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 SPA PF08616.10 EAU83600.2 - 0.0016 18.4 0.0 0.006 16.5 0.0 1.8 1 1 0 1 1 1 1 Stabilization of polarity axis PI-PLC-X PF00388.19 EAU83602.2 - 6.6e-40 136.0 0.0 9.4e-39 132.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EAU83602.2 - 3.5e-27 95.0 0.0 1.5e-26 93.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EAU83602.2 - 0.028 14.7 0.0 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 C2 domain Prefoldin PF02996.17 EAU83606.1 - 6.6e-28 97.0 3.1 8.4e-28 96.7 3.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EAU83606.1 - 0.00017 21.6 0.7 0.0003 20.8 0.3 1.7 1 1 0 1 1 1 1 Prefoldin subunit Dynamitin PF04912.14 EAU83606.1 - 0.0017 17.8 2.5 0.0019 17.6 2.5 1.1 1 0 0 1 1 1 1 Dynamitin Prefoldin_2 PF01920.20 EAU83606.1 - 0.0056 16.6 7.4 0.046 13.7 0.8 2.3 2 0 0 2 2 2 2 Prefoldin subunit AIP3 PF03915.13 EAU83606.1 - 0.0068 15.5 1.2 0.0078 15.4 1.2 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 UPF0449 PF15136.6 EAU83606.1 - 0.009 16.5 2.8 0.46 11.0 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 CLZ PF16526.5 EAU83606.1 - 0.011 16.1 2.9 3.3 8.1 0.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Baculo_PEP_C PF04513.12 EAU83606.1 - 0.013 15.6 1.5 1.5 8.9 0.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.11 EAU83606.1 - 0.013 15.6 0.9 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med30 PF11315.8 EAU83606.1 - 0.028 14.6 2.5 0.071 13.3 0.9 2.0 1 1 1 2 2 2 0 Mediator complex subunit 30 PHM7_cyt PF14703.6 EAU83606.1 - 0.03 14.6 0.7 0.048 13.9 0.7 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter SYCE1 PF15233.6 EAU83606.1 - 0.031 14.4 2.7 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 FlaC_arch PF05377.11 EAU83606.1 - 0.036 14.5 1.9 2.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Filament PF00038.21 EAU83606.1 - 0.038 13.6 4.2 0.11 12.0 0.2 2.0 2 0 0 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 EAU83606.1 - 0.071 13.3 7.0 4.9 7.3 7.0 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family T3SSipB PF16535.5 EAU83606.1 - 0.075 13.5 8.5 0.11 13.0 1.9 2.1 2 0 0 2 2 2 0 Type III cell invasion protein SipB RasGAP_C PF03836.15 EAU83606.1 - 0.079 13.1 4.3 0.46 10.6 0.4 2.1 2 0 0 2 2 2 0 RasGAP C-terminus CEP63 PF17045.5 EAU83606.1 - 0.082 12.8 3.6 0.59 10.0 0.1 2.1 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF4164 PF13747.6 EAU83606.1 - 0.11 12.8 1.1 12 6.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TMF_TATA_bd PF12325.8 EAU83606.1 - 0.19 12.0 3.7 0.21 11.8 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CC2-LZ PF16516.5 EAU83606.1 - 0.38 11.1 7.8 0.21 12.0 1.6 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF5082 PF16888.5 EAU83606.1 - 0.42 10.9 7.5 1.4 9.2 2.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 EAU83606.1 - 0.42 10.6 4.0 1.6 8.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EAU83606.1 - 0.44 9.4 6.6 0.61 8.9 1.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 EAU83606.1 - 0.69 9.7 8.0 2.7 7.8 3.1 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 DHR10 PF18595.1 EAU83606.1 - 2.1 8.4 8.9 6.3 6.9 0.9 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Pex26 PF07163.12 EAU83608.1 - 0.029 13.7 0.2 0.042 13.1 0.2 1.2 1 0 0 1 1 1 0 Pex26 protein Methyltransf_23 PF13489.6 EAU83609.1 - 1.3e-12 47.9 0.0 1.6e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU83609.1 - 5.3e-06 27.0 0.0 7.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU83609.1 - 0.00012 22.7 0.0 0.00025 21.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU83609.1 - 0.00012 22.7 0.0 0.0002 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU83609.1 - 0.0042 16.9 0.0 0.052 13.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EAU83609.1 - 0.25 10.4 0.0 0.4 9.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NACHT PF05729.12 EAU83610.1 - 1.7e-07 31.3 0.1 3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83610.1 - 4.4e-05 23.9 0.2 7.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAU83610.1 - 0.013 16.0 0.0 0.038 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DDE_Tnp_IS66_C PF13817.6 EAU83610.1 - 0.32 11.2 1.2 20 5.5 0.0 3.4 3 0 0 3 3 3 0 IS66 C-terminal element PAP2_3 PF14378.6 EAU83611.1 - 8e-24 84.4 17.9 8e-24 84.4 17.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EAU83611.1 - 9.5e-11 41.6 5.6 9.5e-11 41.6 5.6 2.6 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 EAU83611.1 - 2.4 8.7 16.3 0.15 12.6 6.2 3.2 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Questin_oxidase PF14027.6 EAU83612.2 - 1e-94 317.9 0.0 1.4e-94 317.4 0.0 1.2 1 0 0 1 1 1 1 Questin oxidase-like MAGE PF01454.19 EAU83614.2 - 1.8e-49 168.4 0.0 2.6e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 MAGE family Sugar_tr PF00083.24 EAU83615.1 - 1.6e-122 409.7 24.6 1.6e-122 409.7 24.6 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU83615.1 - 2.1e-18 66.4 40.7 1.1e-12 47.6 18.4 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF2530 PF10745.9 EAU83615.1 - 0.37 11.1 7.5 0.27 11.5 4.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) NACHT PF05729.12 EAU83616.1 - 1.5e-06 28.3 0.1 3.1e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83616.1 - 0.028 14.8 0.2 0.066 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EAU83616.1 - 0.038 14.4 0.0 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DDE_Tnp_IS66_C PF13817.6 EAU83616.1 - 0.22 11.8 2.6 14 6.0 0.1 3.6 4 0 0 4 4 4 0 IS66 C-terminal element Peptidase_M36 PF02128.15 EAU83617.1 - 6.5e-161 535.6 1.3 8.7e-161 535.2 1.3 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EAU83617.1 - 6e-15 54.8 2.8 1.3e-14 53.7 2.8 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif RhoGEF PF00621.20 EAU83618.1 - 6.4e-16 59.1 0.0 1.1e-15 58.4 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.20 EAU83619.2 - 2.1e-60 204.5 18.2 2.1e-60 204.5 18.2 1.8 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 EAU83619.2 - 1.6e-12 47.3 0.0 4.3e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EAU83619.2 - 1e-10 41.2 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EAU83619.2 - 0.083 13.2 0.1 0.22 11.9 0.1 1.8 1 0 0 1 1 1 0 STAS domain DUF997 PF06196.12 EAU83619.2 - 2.3 8.3 6.5 0.4 10.7 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF997) NUDIX_2 PF13869.6 EAU83620.1 - 5e-84 280.6 0.0 5.7e-84 280.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ion_trans PF00520.31 EAU83622.2 - 2.4e-106 354.4 79.7 1.6e-35 122.5 12.9 6.1 5 1 1 6 6 6 6 Ion transport protein p450 PF00067.22 EAU83624.2 - 4.8e-33 114.6 0.0 6.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PCI PF01399.27 EAU83625.1 - 7.9e-08 32.8 6.4 1.3e-06 28.9 0.0 3.4 4 0 0 4 4 4 2 PCI domain GTP_EFTU PF00009.27 EAU83626.1 - 3.4e-59 199.7 0.0 7e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EAU83626.1 - 1.2e-39 134.9 0.2 6.9e-39 132.4 0.1 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 EAU83626.1 - 1.2e-30 105.4 0.0 2.4e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EAU83626.1 - 6.2e-22 77.4 0.1 2.8e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAU83626.1 - 9e-13 48.4 0.0 2.4e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EAU83626.1 - 1.2e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ank_2 PF12796.7 EAU83627.2 - 3e-77 255.3 2.8 1e-14 54.8 0.0 7.7 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAU83627.2 - 6.4e-47 156.0 3.3 0.00093 19.5 0.0 13.5 13 0 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.6 EAU83627.2 - 9.2e-46 153.7 14.7 3.9e-09 36.9 0.1 11.6 2 1 10 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU83627.2 - 1.4e-44 144.9 0.2 0.0033 17.8 0.0 13.2 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.6 EAU83627.2 - 2.6e-36 123.2 14.7 3.8e-06 27.1 0.1 7.9 5 3 1 7 7 7 6 Ankyrin repeats (many copies) E3_binding PF02817.17 EAU83627.2 - 0.056 13.8 2.4 0.65 10.4 0.0 3.7 5 0 0 5 5 5 0 e3 binding domain DUF1179 PF06678.11 EAU83628.2 - 0.47 10.5 6.7 0.4 10.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) CBFD_NFYB_HMF PF00808.23 EAU83629.1 - 1.6e-06 28.3 0.5 2.8e-06 27.5 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EAU83629.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Tenui_NCP PF04876.12 EAU83629.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein Acid_PPase PF12689.7 EAU83634.1 - 1e-59 201.1 0.0 1.2e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HTH_7 PF02796.15 EAU83634.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Defensin_3 PF08131.11 EAU83635.1 - 0.082 13.1 2.6 0.17 12.1 2.4 1.7 1 1 0 1 1 1 0 Defensin-like peptide family Kdo PF06293.14 EAU83637.2 - 1.4e-06 27.8 0.0 3.6e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU83637.2 - 2.1e-05 24.6 0.0 0.00052 20.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EAU83637.2 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.20 EAU83637.2 - 0.0069 15.7 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.17 EAU83637.2 - 0.081 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU83637.2 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4813 PF16072.5 EAU83637.2 - 0.21 11.2 0.6 0.31 10.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Defensin_3 PF08131.11 EAU83640.2 - 0.029 14.6 3.3 0.06 13.5 3.0 1.7 1 1 0 1 1 1 0 Defensin-like peptide family HAMP PF00672.25 EAU83641.2 - 3.3e-34 117.0 10.0 2e-07 31.2 0.1 6.1 5 1 0 5 5 5 5 HAMP domain Phage_tube PF04985.14 EAU83641.2 - 0.0021 17.8 5.7 2.3 7.9 0.1 4.2 3 1 1 4 4 4 2 Phage tail tube protein FII DUF948 PF06103.11 EAU83641.2 - 0.03 14.6 31.8 5.1 7.4 5.8 8.0 5 2 2 7 7 7 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EAU83641.2 - 0.034 14.3 3.1 5 7.3 0.1 4.2 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family PurA PF04845.13 EAU83641.2 - 0.036 13.4 0.2 9 5.6 0.0 2.4 1 1 1 2 2 2 0 PurA ssDNA and RNA-binding protein SpoIIID PF12116.8 EAU83641.2 - 0.19 11.9 0.7 35 4.6 0.0 3.4 3 0 0 3 3 3 0 Stage III sporulation protein D FlaC_arch PF05377.11 EAU83641.2 - 0.2 12.1 5.2 13 6.2 0.2 4.5 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Mito_fiss_reg PF05308.11 EAU83641.2 - 1.5 8.8 4.8 4.8 7.2 4.8 1.8 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box-like PF12937.7 EAU83642.2 - 5.3e-08 32.6 0.1 1.7e-07 31.0 0.1 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU83642.2 - 0.032 14.1 1.2 1.3 9.0 0.1 2.7 2 0 0 2 2 2 0 F-box domain CBM_1 PF00734.18 EAU83644.2 - 5.3e-05 23.1 3.0 7.8e-05 22.6 3.0 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.18 EAU83646.2 - 0.0067 16.4 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Clathrin-link PF09268.10 EAU83650.2 - 2.7 7.5 5.9 6 6.3 0.6 2.3 2 0 0 2 2 2 0 Clathrin, heavy-chain linker DUF1996 PF09362.10 EAU83652.2 - 1.8e-64 218.0 0.0 1.8e-64 218.0 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 EAU83655.2 - 7.1e-63 212.7 1.0 8.4e-63 212.5 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4448 PF14610.6 EAU83656.1 - 0.00028 20.7 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CENP-B_dimeris PF09026.10 EAU83656.1 - 0.012 16.0 2.8 0.012 16.0 2.8 1.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GPI-anchored PF10342.9 EAU83656.1 - 0.025 15.3 0.0 0.056 14.2 0.0 1.6 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NOA36 PF06524.12 EAU83656.1 - 0.74 9.1 4.3 0.95 8.7 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4448 PF14610.6 EAU83657.1 - 0.0016 18.2 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.9 EAU83657.1 - 0.0032 18.2 0.0 0.0088 16.8 0.0 1.8 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.10 EAU83657.1 - 0.072 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box-like PF12937.7 EAU83662.1 - 0.0012 18.7 0.5 0.013 15.4 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU83662.1 - 0.0092 15.8 0.6 0.15 12.0 0.6 2.5 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU83663.2 - 0.00013 21.8 0.1 0.00041 20.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU83663.2 - 0.00043 20.1 3.0 0.00089 19.1 0.8 2.7 2 1 0 2 2 2 1 F-box domain TFIIB PF00382.19 EAU83664.2 - 1.2e-35 121.4 0.5 4.1e-18 65.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EAU83664.2 - 4e-26 91.3 0.9 4e-26 91.3 0.9 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EAU83664.2 - 2.3e-08 33.4 2.5 5.3e-08 32.3 2.5 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EAU83664.2 - 6.1e-05 22.8 0.5 0.031 14.0 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 EAU83664.2 - 0.00025 21.0 1.3 0.00051 20.0 1.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon TackOD1 PF18551.1 EAU83664.2 - 0.017 14.8 0.4 0.034 13.8 0.4 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Ribosomal_S27e PF01667.17 EAU83664.2 - 0.17 11.7 1.4 0.36 10.6 1.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 AP3D1 PF06375.11 EAU83664.2 - 5.4 7.2 9.9 0.52 10.5 3.5 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 TatD_DNase PF01026.21 EAU83670.1 - 3.9e-45 154.2 0.1 4.7e-45 153.9 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EAU83670.1 - 0.011 15.6 0.0 0.031 14.1 0.0 2.0 1 1 0 1 1 1 0 Amidohydrolase F-box-like PF12937.7 EAU83671.1 - 0.00031 20.6 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU83671.1 - 0.00032 20.5 1.0 0.0078 16.1 1.0 2.5 1 1 0 1 1 1 1 F-box domain F-box PF00646.33 EAU83672.1 - 0.0048 16.7 0.5 0.043 13.7 0.1 2.7 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAU83672.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 F-box-like PBP PF01161.20 EAU83673.1 - 1e-18 67.9 0.0 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Prenyltrans PF00432.21 EAU83674.2 - 3.5e-36 122.6 8.2 2e-07 30.6 0.0 6.7 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EAU83674.2 - 0.17 11.0 0.0 7.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Glyoxalase PF00903.25 EAU83676.1 - 5.4e-07 29.8 0.0 6.3e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EAU83676.1 - 0.01 16.6 0.0 0.022 15.5 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain Porin_O_P PF07396.11 EAU83676.1 - 0.082 12.1 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosphate-selective porin O and P Sacchrp_dh_C PF16653.5 EAU83678.1 - 2.3e-90 303.3 0.0 4.1e-90 302.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 EAU83678.1 - 2.1e-66 222.9 0.0 4.3e-66 221.9 0.0 1.5 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 EAU83678.1 - 1.9e-27 96.1 2.2 6.4e-27 94.4 0.2 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 EAU83678.1 - 1.1e-23 82.8 1.4 2.7e-23 81.6 0.2 2.2 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 EAU83678.1 - 2.3e-08 34.2 0.2 1.1e-06 28.8 0.0 2.9 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 EAU83678.1 - 4.9e-07 30.4 0.0 1.6e-05 25.5 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain NAD_binding_10 PF13460.6 EAU83678.1 - 1.5e-05 25.0 0.1 2.7e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_11 PF08241.12 EAU83678.1 - 0.00034 21.2 0.0 0.28 11.8 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain F420_oxidored PF03807.17 EAU83678.1 - 0.00098 19.7 0.0 0.0026 18.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Methyltransf_12 PF08242.12 EAU83678.1 - 0.0019 18.9 0.1 0.03 15.1 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain GFO_IDH_MocA PF01408.22 EAU83678.1 - 0.021 15.6 0.5 0.065 14.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EAU83678.1 - 0.026 15.2 0.1 0.058 14.1 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain MTS PF05175.14 EAU83678.1 - 0.05 13.1 0.0 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.7 EAU83678.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Omp28 PF11551.8 EAU83679.2 - 0.1 12.4 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Outer membrane protein Omp28 F-box-like PF12937.7 EAU83680.1 - 8.8e-06 25.5 0.4 2.1e-05 24.3 0.4 1.6 1 0 0 1 1 1 1 F-box-like Tet_JBP PF12851.7 EAU83685.2 - 1.9e-08 34.1 0.0 2.9e-07 30.2 0.0 2.0 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily DUF1664 PF07889.12 EAU83688.1 - 0.00012 22.1 2.3 0.22 11.6 0.2 3.3 2 1 0 3 3 3 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EAU83688.1 - 0.00078 19.5 0.8 0.038 14.0 0.0 3.0 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus CHASE3 PF05227.13 EAU83688.1 - 0.0022 17.9 0.5 0.0065 16.4 0.3 1.9 1 1 0 1 1 1 1 CHASE3 domain Macoilin PF09726.9 EAU83688.1 - 0.003 16.2 0.0 0.003 16.2 0.0 2.1 2 0 0 2 2 2 1 Macoilin family Filament PF00038.21 EAU83688.1 - 0.01 15.4 0.5 0.025 14.1 0.5 1.6 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 EAU83688.1 - 0.011 14.6 0.1 0.026 13.4 0.1 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.12 EAU83688.1 - 0.024 12.8 0.8 0.036 12.2 0.8 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Laminin_I PF06008.14 EAU83688.1 - 0.032 14.0 0.4 0.084 12.6 0.4 1.7 1 0 0 1 1 1 0 Laminin Domain I Apolipoprotein PF01442.18 EAU83688.1 - 0.035 14.0 9.5 0.041 13.7 5.7 2.6 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain COG2 PF06148.11 EAU83688.1 - 0.044 13.9 0.2 0.21 11.6 0.0 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 EAU83688.1 - 0.055 13.5 0.4 41 4.3 0.0 3.5 3 0 0 3 3 3 0 TolA binding protein trimerisation Golgin_A5 PF09787.9 EAU83688.1 - 0.086 12.3 1.4 0.19 11.2 1.4 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EAU83688.1 - 0.097 12.8 0.4 0.33 11.0 0.3 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 EAU83688.1 - 0.12 12.8 0.9 28 5.2 0.1 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 EAU83688.1 - 0.13 12.3 1.2 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 EAU83688.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.19 EAU83688.1 - 0.27 9.1 0.3 0.63 7.9 0.2 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM104 PF15434.6 EAU83688.1 - 0.91 10.1 7.4 0.17 12.5 2.9 2.1 2 0 0 2 2 2 0 Family 104 Mucin PF01456.17 EAU83688.1 - 1.6 8.8 27.4 0.031 14.2 20.3 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Tropomyosin PF00261.20 EAU83688.1 - 2.4 7.5 5.2 4.7 6.5 5.2 1.4 1 0 0 1 1 1 0 Tropomyosin SKA2 PF16740.5 EAU83688.1 - 3.9 7.3 6.0 12 5.7 0.0 3.3 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 F-box-like PF12937.7 EAU83693.1 - 6.9e-05 22.7 0.5 0.00017 21.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like HMG_box PF00505.19 EAU83694.1 - 3.8e-08 33.6 0.0 6.9e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box Tyrosinase PF00264.20 EAU83695.1 - 3.2e-42 145.3 0.0 4.3e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Asp-Al_Ex PF06826.12 EAU83696.1 - 0.0048 16.7 0.1 0.0065 16.3 0.1 1.2 1 0 0 1 1 1 1 Predicted Permease Membrane Region Plavaka PF18759.1 EAU83698.2 - 1.5e-25 90.1 0.0 3.4e-25 88.9 0.0 1.5 1 1 0 1 1 1 1 Plavaka transposase Ion_trans_2 PF07885.16 EAU83700.2 - 5e-24 84.1 24.7 3.3e-14 52.6 8.8 2.7 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 EAU83700.2 - 0.19 11.0 14.4 0.085 12.1 3.5 2.3 2 0 0 2 2 2 0 Ion transport protein DUF4834 PF16118.5 EAU83700.2 - 0.27 12.2 2.8 26 5.9 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Flp_Fap PF04964.14 EAU83703.2 - 0.23 11.3 4.1 11 6.0 0.0 3.2 3 0 0 3 3 3 0 Flp/Fap pilin component UQ_con PF00179.26 EAU83704.2 - 3.1e-07 30.1 0.0 7.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PARP PF00644.20 EAU83704.2 - 1.8e-05 24.4 0.0 5.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RWD PF05773.22 EAU83704.2 - 0.14 12.5 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 RWD domain AMP-binding PF00501.28 EAU83705.2 - 8.4e-41 139.9 0.0 9.7e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU83705.2 - 5.3e-13 49.7 0.1 1.2e-12 48.6 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EAU83706.1 - 4.8e-26 91.3 0.0 7.8e-26 90.6 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme CCT_2 PF09425.10 EAU83707.1 - 0.011 15.6 2.4 0.027 14.3 2.4 1.7 1 0 0 1 1 1 0 Divergent CCT motif LRR_4 PF12799.7 EAU83707.1 - 1.5 9.4 8.5 10 6.7 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU83709.1 - 1.7e-06 27.8 2.4 4.5e-06 26.5 2.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU83709.1 - 0.0027 18.1 0.8 1.3 9.6 0.0 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Protoglobin PF11563.8 EAU83711.1 - 8.7e-52 175.2 0.1 1e-51 175.0 0.1 1.0 1 0 0 1 1 1 1 Protoglobin Sugar_tr PF00083.24 EAU83712.1 - 9.7e-110 367.5 17.7 1.1e-109 367.3 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU83712.1 - 3.5e-21 75.5 24.8 3.5e-21 75.5 24.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TMEM107 PF14995.6 EAU83712.1 - 0.021 15.3 0.7 0.074 13.5 0.7 1.9 1 0 0 1 1 1 0 Transmembrane protein DUF4381 PF14316.6 EAU83712.1 - 0.17 12.2 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) F-box-like PF12937.7 EAU83713.1 - 4.3e-05 23.3 0.8 0.0005 19.9 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU83713.1 - 0.022 14.6 0.1 0.088 12.7 0.1 2.0 2 0 0 2 2 2 0 F-box domain WD40 PF00400.32 EAU83715.2 - 1.3e-23 82.8 12.4 7.9e-05 23.3 0.6 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU83715.2 - 1.1e-07 32.0 4.7 0.076 13.3 0.1 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU83715.2 - 7.3e-07 28.5 0.0 0.18 10.7 0.0 3.4 2 2 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein p450 PF00067.22 EAU83716.2 - 3.5e-54 184.3 0.0 5e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.6 EAU83718.1 - 2.1e-16 60.1 0.0 2.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU83718.1 - 1.2e-13 51.2 0.0 1.7e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU83718.1 - 2.9e-11 43.9 0.0 5.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU83718.1 - 2.9e-11 43.9 0.0 6.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU83718.1 - 2.1e-10 41.2 0.0 3.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAU83718.1 - 8.4e-07 29.0 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EAU83718.1 - 1.1e-06 28.1 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Sterol_MT_C PF08498.10 EAU83718.1 - 6.9e-06 26.3 0.1 2.1e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.20 EAU83718.1 - 9.3e-06 25.1 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EAU83718.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 EAU83718.1 - 0.062 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.12 EAU83718.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Bmt2 PF11968.8 EAU83718.1 - 0.2 11.5 0.0 1.8 8.4 0.0 2.0 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 p450 PF00067.22 EAU83724.2 - 1.3e-15 57.1 0.1 4e-15 55.5 0.1 1.6 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EAU83726.1 - 5.6e-16 58.7 0.0 4.2e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU83726.1 - 3.5e-06 26.5 0.1 0.0013 18.1 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EAU83726.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 EAU83727.2 - 6.8e-07 29.1 2.2 2.5e-06 27.3 1.2 2.4 2 0 0 2 2 2 1 F-box-like Na_H_Exchanger PF00999.21 EAU83728.2 - 1.3e-54 185.4 48.0 1.8e-54 185.0 48.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PCNA_N PF00705.18 EAU83729.1 - 1.6e-52 176.5 2.0 8.5e-52 174.2 2.5 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EAU83729.1 - 1.1e-41 141.9 0.0 1e-19 71.0 0.0 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EAU83729.1 - 0.001 18.6 0.0 0.017 14.6 0.0 2.5 2 1 0 2 2 2 1 Rad9 BUD22 PF09073.10 EAU83729.1 - 0.27 10.5 26.4 0.39 10.0 26.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EAU83729.1 - 0.37 10.2 31.8 0.52 9.7 31.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EAU83729.1 - 0.66 8.1 29.2 0.92 7.6 29.2 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 EAU83729.1 - 2.5 7.8 13.1 4 7.2 13.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tub_N PF16322.5 EAU83729.1 - 2.6 8.4 18.6 3.9 7.8 18.6 1.3 1 0 0 1 1 1 0 Tubby N-terminal Hid1 PF12722.7 EAU83729.1 - 4.2 5.4 7.8 5.2 5.1 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NAPRTase_N PF17767.1 EAU83730.1 - 0.069 13.5 0.6 0.12 12.8 0.6 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Tyrosinase PF00264.20 EAU83732.2 - 1e-37 130.6 0.0 1.4e-37 130.1 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase F-box-like PF12937.7 EAU83733.2 - 0.0063 16.4 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU83733.2 - 0.0098 15.7 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain Ntox37 PF15535.6 EAU83734.1 - 0.054 13.9 0.1 0.088 13.3 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 37 Endonuc-BsobI PF09194.10 EAU83743.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BsobI TMEM154 PF15102.6 EAU83745.1 - 0.00016 21.6 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family GRP PF07172.11 EAU83745.1 - 0.012 16.3 13.1 0.012 16.3 13.1 5.3 6 0 0 6 6 6 0 Glycine rich protein family stn_TNFRSF12A PF12191.8 EAU83745.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Tweety PF04906.13 EAU83745.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Tweety SPX PF03105.19 EAU83745.1 - 0.39 10.6 10.6 0.12 12.3 0.8 2.2 2 0 0 2 2 2 0 SPX domain ENTH PF01417.20 EAU83746.1 - 3.2e-50 169.4 0.0 8.5e-50 168.0 0.0 1.8 1 0 0 1 1 1 1 ENTH domain DUF45 PF01863.17 EAU83746.1 - 5.7 6.9 13.5 0.6 10.1 1.2 2.9 3 1 1 4 4 4 0 Protein of unknown function DUF45 Polysacc_deac_1 PF01522.21 EAU83747.2 - 7.6e-06 25.8 0.0 2.3e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.25 EAU83748.2 - 9e-26 90.8 0.0 4.7e-25 88.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU83748.2 - 3.5e-22 78.9 0.0 5.9e-22 78.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAU83748.2 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAU83748.2 - 0.0093 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EAU83748.2 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5435 PF17503.2 EAU83750.2 - 0.13 12.0 1.2 0.21 11.3 1.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5435) SRP-alpha_N PF04086.13 EAU83751.2 - 1.4 8.8 19.3 3.2 7.6 5.4 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Rib_hydrolayse PF02267.17 EAU83753.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 ADP-ribosyl cyclase RNA_Me_trans PF04252.13 EAU83755.1 - 1.1e-74 250.3 0.0 1.2e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Glyco_hydro_10 PF00331.20 EAU83756.2 - 1.1e-30 106.9 0.0 2.2e-15 56.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 EAU83756.2 - 0.022 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Usp PF00582.26 EAU83757.1 - 1.2e-16 61.5 0.0 1.9e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family JAB PF01398.21 EAU83758.2 - 3e-15 56.3 0.2 8.9e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EAU83758.2 - 1.2e-09 38.4 0.0 3.1e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EAU83758.2 - 1.3e-06 28.2 0.0 1.3e-06 28.2 0.0 3.0 3 1 0 3 3 3 1 Prokaryotic homologs of the JAB domain DUF357 PF04010.13 EAU83758.2 - 0.00064 19.7 0.1 0.0016 18.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF357) F-box-like PF12937.7 EAU83760.2 - 5.9e-07 29.3 0.3 1.2e-06 28.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like N2227 PF07942.12 EAU83761.2 - 3.2e-97 325.0 0.0 3.9e-97 324.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EAU83761.2 - 0.0019 18.9 0.0 0.0085 16.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU83761.2 - 0.0026 17.6 0.0 0.024 14.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain GEMIN8 PF15348.6 EAU83761.2 - 0.012 16.0 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SelP_N PF04592.14 EAU83761.2 - 6.8 6.0 12.7 10 5.4 12.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Isy1 PF06246.12 EAU83762.2 - 1.8e-93 312.8 7.3 3.7e-93 311.8 7.3 1.5 1 1 0 1 1 1 1 Isy1-like splicing family UbiA PF01040.18 EAU83763.2 - 4.5e-37 127.7 15.2 9.4e-37 126.7 15.2 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family DEC-1_N PF04625.13 EAU83764.2 - 0.15 11.0 0.3 0.23 10.4 0.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_L31e PF01198.19 EAU83765.1 - 7.1e-41 138.3 0.5 9e-41 138.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CFEM PF05730.11 EAU83766.1 - 9.9e-10 38.4 8.8 1.4e-09 37.9 8.8 1.2 1 0 0 1 1 1 1 CFEM domain API5 PF05918.11 EAU83767.1 - 0.054 12.3 4.4 0.083 11.7 4.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF1682 PF07946.14 EAU83767.1 - 2.1 7.5 14.8 3.5 6.7 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ank_2 PF12796.7 EAU83768.2 - 1.6e-123 403.5 5.5 5.1e-17 62.2 0.1 11.7 2 1 8 12 12 12 11 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU83768.2 - 8.7e-109 342.2 0.4 2.3e-05 24.4 0.0 22.7 23 0 0 23 23 23 19 Ankyrin repeat Ank PF00023.30 EAU83768.2 - 5.3e-92 298.6 29.2 4.7e-06 26.8 0.0 22.7 22 1 1 23 23 22 19 Ankyrin repeat Ank_4 PF13637.6 EAU83768.2 - 1e-82 271.5 18.1 1.5e-05 25.5 0.0 19.7 2 1 19 21 21 21 19 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU83768.2 - 4.5e-78 256.3 34.3 6e-08 32.8 0.1 16.4 4 1 15 20 20 20 17 Ankyrin repeats (many copies) HHH_3 PF12836.7 EAU83768.2 - 0.0001 22.5 9.3 36 4.7 0.0 8.9 11 0 0 11 11 11 0 Helix-hairpin-helix motif AAA_22 PF13401.6 EAU83768.2 - 0.0071 16.6 0.0 0.025 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NapD PF03927.13 EAU83768.2 - 0.014 15.4 8.3 30 4.8 0.0 7.4 6 3 3 9 9 9 0 NapD protein NACHT PF05729.12 EAU83768.2 - 0.029 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EAU83768.2 - 0.12 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TPR_20 PF14561.6 EAU83768.2 - 0.25 11.7 1.1 4.4 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Phosphonate-bd PF12974.7 EAU83768.2 - 0.45 10.1 2.1 1.7 8.2 0.0 2.9 3 1 0 3 3 3 0 ABC transporter, phosphonate, periplasmic substrate-binding protein MFS_1 PF07690.16 EAU83773.2 - 2.7e-39 135.1 15.8 4e-39 134.5 15.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 EAU83773.2 - 0.03 14.2 1.1 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 VIT family SGL PF08450.12 EAU83775.2 - 0.001 18.7 0.3 0.32 10.5 0.2 2.7 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EAU83775.2 - 0.038 14.0 0.3 1.1 9.4 0.0 3.4 4 0 0 4 4 4 0 NHL repeat PD40 PF07676.12 EAU83775.2 - 0.04 13.9 0.2 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SBBP PF06739.11 EAU83775.2 - 0.17 11.9 1.5 0.48 10.5 0.1 2.6 2 0 0 2 2 2 0 Beta-propeller repeat Arylesterase PF01731.20 EAU83775.2 - 0.19 11.9 0.0 34 4.7 0.0 3.1 3 0 0 3 3 3 0 Arylesterase Hemerythrin PF01814.23 EAU83776.2 - 1.5e-05 25.6 0.1 0.00013 22.6 0.1 2.0 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain WW PF00397.26 EAU83777.1 - 7.3e-09 35.6 7.1 7.4e-09 35.6 4.8 2.2 2 0 0 2 2 2 1 WW domain FHA PF00498.26 EAU83778.2 - 5.1e-05 23.5 0.0 8.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAU83778.2 - 0.027 14.8 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain CAP59_mtransfer PF11735.8 EAU83779.1 - 1.9e-68 230.7 0.0 2.5e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Nop53 PF07767.11 EAU83781.2 - 5.8e-102 342.0 26.8 9.1e-102 341.4 26.8 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.12 EAU83781.2 - 1.6 8.6 14.3 0.23 11.4 6.8 2.7 2 1 0 2 2 2 0 BOP1NT (NUC169) domain Ank_2 PF12796.7 EAU83782.2 - 7.9e-91 298.8 0.0 4.9e-13 49.5 0.1 8.7 1 1 9 10 10 10 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU83782.2 - 1.7e-70 224.5 0.0 7.4e-06 25.9 0.0 15.7 15 0 0 15 15 15 14 Ankyrin repeat Ank PF00023.30 EAU83782.2 - 9.6e-61 199.7 8.5 2.7e-05 24.4 0.0 15.7 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 EAU83782.2 - 1.4e-53 178.2 18.7 2.3e-08 34.1 0.2 11.0 5 4 5 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU83782.2 - 4.5e-39 132.3 12.1 6.6e-06 26.6 0.0 14.1 5 3 9 14 14 14 12 Ankyrin repeats (many copies) RPN7 PF10602.9 EAU83783.2 - 4.7e-41 140.4 1.7 7.3e-41 139.8 1.7 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EAU83783.2 - 9.9e-16 58.2 0.7 3.3e-15 56.5 0.1 2.2 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EAU83783.2 - 9.7e-06 25.3 0.1 0.36 11.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU83783.2 - 0.00031 21.0 0.3 0.015 15.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU83783.2 - 0.0021 18.0 0.1 0.65 10.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat dsDNA_bind PF01984.20 EAU83783.2 - 0.0029 17.9 0.0 0.0081 16.4 0.0 1.7 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TPR_1 PF00515.28 EAU83783.2 - 0.018 14.8 0.3 10 6.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EAU83783.2 - 0.1 13.0 0.1 0.1 13.0 0.1 3.2 3 2 1 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 EAU83784.1 - 2.3e-37 128.7 13.8 2.3e-37 128.7 13.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 EAU83784.1 - 0.0058 16.0 8.2 0.0063 15.8 3.1 2.3 2 0 0 2 2 2 1 Sporulation factor SpoIIGA S_4TM PF18159.1 EAU83784.1 - 0.37 10.0 3.9 0.47 9.7 0.1 2.5 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain TPR_10 PF13374.6 EAU83785.2 - 2.9e-45 150.9 0.3 8.5e-08 31.8 0.1 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat CHAT PF12770.7 EAU83785.2 - 1e-26 94.0 0.0 1.7e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU83785.2 - 2.8e-17 62.8 2.1 0.036 14.4 0.1 8.1 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 EAU83785.2 - 3.3e-06 27.1 3.8 3.8 8.1 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat MAGI_u1 PF16663.5 EAU83785.2 - 0.008 16.2 0.0 99 3.1 0.0 5.4 6 0 0 6 6 6 0 Unstructured region on MAGI DUF4404 PF14357.6 EAU83785.2 - 0.0088 16.7 2.5 25 5.6 0.0 5.3 3 2 2 6 6 6 1 Domain of unknown function (DUF4404) TPR_1 PF00515.28 EAU83785.2 - 1.2 9.1 14.7 73 3.4 0.1 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat SET PF00856.28 EAU83786.1 - 5.3e-12 46.4 0.0 2.2e-11 44.4 0.0 2.1 2 1 0 2 2 2 1 SET domain SET PF00856.28 EAU83787.2 - 4.5e-12 46.7 0.0 4.2e-11 43.5 0.0 2.3 1 1 0 1 1 1 1 SET domain Ank_2 PF12796.7 EAU83788.1 - 2.7e-36 124.0 3.5 7.5e-15 55.3 0.1 5.1 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU83788.1 - 3.1e-29 100.7 8.1 9.9e-07 28.9 0.1 7.8 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU83788.1 - 2.3e-27 92.0 8.1 0.00047 20.4 0.0 10.0 10 0 0 10 10 9 5 Ankyrin repeat Ank_4 PF13637.6 EAU83788.1 - 4.4e-27 94.1 2.4 9.5e-09 35.6 0.1 8.2 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU83788.1 - 5.1e-24 83.6 7.0 0.0062 16.9 0.0 9.5 8 1 1 9 9 9 4 Ankyrin repeat AAA_22 PF13401.6 EAU83788.1 - 4.1e-07 30.4 0.0 3.5e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU83788.1 - 0.00033 20.6 0.0 0.00093 19.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83788.1 - 0.0033 17.8 1.0 0.013 15.8 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 EAU83788.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain Radial_spoke PF04712.12 EAU83788.1 - 0.085 11.8 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2075 PF09848.9 EAU83788.1 - 0.086 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EAU83788.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 NTPase Ank_2 PF12796.7 EAU83789.2 - 1.3e-29 102.6 3.5 2.8e-11 43.9 0.1 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU83789.2 - 4.6e-25 87.3 8.0 8.1e-08 32.4 0.1 7.5 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU83789.2 - 2.2e-22 76.7 2.6 0.038 14.5 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 EAU83789.2 - 2.4e-17 63.1 6.0 1.5e-05 25.5 0.1 6.5 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU83789.2 - 6.4e-16 58.0 9.1 0.23 12.0 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat AAA_22 PF13401.6 EAU83789.2 - 1.4e-06 28.6 0.0 4.2e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU83789.2 - 0.00034 20.6 0.0 0.00092 19.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83789.2 - 0.0017 18.8 0.3 0.012 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EAU83789.2 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EAU83789.2 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.7 EAU83790.1 - 4.9e-46 155.2 10.3 8.9e-16 58.3 0.0 5.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU83790.1 - 5.3e-28 94.0 3.5 0.00017 21.7 0.0 9.7 9 0 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.6 EAU83790.1 - 1.5e-23 82.9 0.0 6.7e-06 26.5 0.0 6.8 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU83790.1 - 3.2e-23 81.5 4.4 3.3e-06 27.3 0.2 7.0 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EAU83790.1 - 1.7e-21 75.6 9.3 0.0016 18.8 0.0 9.7 9 1 0 9 9 9 4 Ankyrin repeat AAA_22 PF13401.6 EAU83790.1 - 1e-06 29.0 0.0 6.3e-06 26.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EAU83790.1 - 0.0002 21.4 0.0 0.00057 19.8 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83790.1 - 0.0013 19.1 0.2 0.0074 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EAU83790.1 - 0.094 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EAU83790.1 - 0.094 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HTH_12 PF08461.10 EAU83790.1 - 0.97 9.4 6.1 0.06 13.3 0.5 1.9 2 0 0 2 2 1 0 Ribonuclease R winged-helix domain Ank_2 PF12796.7 EAU83791.1 - 3.3e-35 120.5 0.1 2.8e-15 56.6 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU83791.1 - 3.6e-25 87.7 1.8 0.0002 21.6 0.4 7.5 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU83791.1 - 4.4e-21 72.7 0.4 0.0029 17.9 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 EAU83791.1 - 2.5e-20 72.6 1.5 1.7e-06 28.4 0.1 7.0 4 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EAU83791.1 - 5e-20 71.0 8.6 0.003 17.9 0.0 8.4 8 1 0 8 8 8 5 Ankyrin repeat AAA_22 PF13401.6 EAU83791.1 - 1.9e-06 28.2 0.0 6.6e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU83791.1 - 0.0015 18.9 0.3 0.17 12.3 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EAU83791.1 - 0.0049 16.8 0.0 0.017 15.0 0.0 2.0 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 EAU83791.1 - 0.054 12.7 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Peptidase_S15 PF02129.18 EAU83791.1 - 0.15 11.7 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SOGA PF11365.8 EAU83792.2 - 0.022 15.9 0.9 0.083 14.0 0.9 2.0 1 0 0 1 1 1 0 Protein SOGA PhaP_Bmeg PF09602.10 EAU83792.2 - 0.023 14.6 0.7 0.023 14.6 0.7 1.7 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4618 PF15397.6 EAU83792.2 - 0.034 13.6 0.9 0.061 12.7 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Choline_kinase PF01633.20 EAU83792.2 - 0.068 12.7 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase D123 PF07065.14 EAU83792.2 - 0.69 9.0 3.8 1.5 7.9 0.6 2.3 2 0 0 2 2 2 0 D123 Aminotran_1_2 PF00155.21 EAU83793.1 - 2.2e-39 135.7 0.0 2.7e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EAU83793.1 - 0.0062 15.1 0.0 0.011 14.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_11 PF08279.12 EAU83793.1 - 0.063 13.2 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 HTH domain Con-6 PF10346.9 EAU83796.2 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Conidiation protein 6 Ank_2 PF12796.7 EAU83797.2 - 2.6e-46 156.1 0.5 1.1e-16 61.2 0.0 4.9 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU83797.2 - 4.3e-30 100.4 1.4 0.0003 21.0 0.0 9.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAU83797.2 - 1.5e-27 95.2 8.1 1e-06 28.9 0.1 8.2 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU83797.2 - 5.1e-25 87.5 4.4 2.9e-07 30.9 0.0 7.6 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU83797.2 - 2.4e-20 72.0 3.8 0.0026 18.2 0.0 8.4 7 1 1 8 8 8 4 Ankyrin repeat AAA_22 PF13401.6 EAU83797.2 - 1.9e-07 31.5 0.0 5.8e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU83797.2 - 9.7e-05 22.3 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU83797.2 - 0.0009 19.7 0.1 0.005 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 EAU83797.2 - 0.062 12.5 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EAU83797.2 - 0.085 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Con-6 PF10346.9 EAU83798.2 - 1.8e-17 63.0 0.4 2.7e-17 62.5 0.4 1.3 1 0 0 1 1 1 1 Conidiation protein 6 TIMELESS PF04821.14 EAU83799.2 - 1.1e-85 287.3 0.8 1.1e-85 287.3 0.8 1.9 2 0 0 2 2 2 1 Timeless protein bZIP_2 PF07716.15 EAU83801.2 - 2.3e-05 24.4 8.4 0.00066 19.7 1.3 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EAU83801.2 - 7.6e-05 22.7 7.6 0.0024 17.9 3.5 2.3 2 0 0 2 2 2 2 bZIP transcription factor CALCOCO1 PF07888.11 EAU83801.2 - 0.015 14.2 0.4 0.021 13.7 0.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ZapB PF06005.12 EAU83801.2 - 0.043 14.3 0.6 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF641 PF04859.12 EAU83801.2 - 0.044 14.1 2.3 0.17 12.2 2.3 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) TM231 PF10149.9 EAU83801.2 - 0.072 12.4 0.4 0.1 11.9 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 231 SIKE PF05769.11 EAU83801.2 - 0.075 13.0 1.5 0.14 12.1 1.5 1.4 1 1 0 1 1 1 0 SIKE family HALZ PF02183.18 EAU83801.2 - 0.079 13.2 1.0 0.17 12.1 1.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF4763 PF15960.5 EAU83801.2 - 0.096 12.0 1.4 0.16 11.3 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) GOLGA2L5 PF15070.6 EAU83801.2 - 0.097 11.3 1.9 0.14 10.8 1.9 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.15 EAU83801.2 - 0.17 11.7 3.4 1.1 9.1 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator PKcGMP_CC PF16808.5 EAU83801.2 - 0.21 11.5 2.5 0.43 10.5 2.5 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 EAU83801.2 - 2.3 8.9 9.7 0.88 10.2 3.0 3.0 2 1 1 3 3 3 0 SlyX ATG16 PF08614.11 EAU83801.2 - 5.4 7.2 9.5 2.7e+02 1.6 9.6 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TAL_FSA PF00923.19 EAU83802.2 - 5.1e-25 88.4 0.0 6.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Hydrolase_6 PF13344.6 EAU83803.1 - 5.6e-31 106.6 0.0 1.2e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU83803.1 - 3.7e-18 65.4 0.0 8.1e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EAU83803.1 - 4.1e-10 40.3 0.0 1e-09 39.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EAU83803.1 - 5.3e-08 33.2 0.0 0.00096 19.3 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EAU83803.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Ribosomal_L7Ae PF01248.26 EAU83803.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PIG-F PF06699.11 EAU83804.1 - 1.5e-33 116.5 2.5 1.6e-33 116.4 1.5 1.5 1 1 1 2 2 2 1 GPI biosynthesis protein family Pig-F Ribosomal_L34e PF01199.18 EAU83805.1 - 3e-43 146.0 2.2 4.6e-43 145.5 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 EAU83805.1 - 0.067 13.1 2.5 2.4 8.2 0.4 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain DUF89 PF01937.19 EAU83809.2 - 2.6e-104 349.0 0.0 3.3e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 NDUFV3 PF15880.5 EAU83809.2 - 0.027 14.5 0.1 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial Con-6 PF10346.9 EAU83811.2 - 2.2e-10 40.4 1.0 2e-09 37.3 1.0 2.1 1 1 0 1 1 1 1 Conidiation protein 6 LRR_4 PF12799.7 EAU83812.1 - 0.019 15.4 0.4 4.7 7.8 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Cation_efflux PF01545.21 EAU83814.1 - 0.0013 18.5 3.8 0.0013 18.5 3.8 2.4 2 1 0 2 2 2 1 Cation efflux family Lipase_3 PF01764.25 EAU83815.2 - 1.7e-15 57.2 0.1 4.5e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAU83815.2 - 0.0083 16.8 0.1 0.015 15.9 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family RMI1_N PF08585.12 EAU83821.1 - 3.2e-15 56.5 0.0 4.4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Presenilin PF01080.17 EAU83822.1 - 0.82 8.4 1.7 1.2 7.8 1.7 1.1 1 0 0 1 1 1 0 Presenilin DUF5598 PF18127.1 EAU83826.2 - 0.0018 18.7 0.0 2.3 8.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5598) zf-HC2 PF13490.6 EAU83826.2 - 0.77 10.1 3.0 27 5.1 0.3 2.6 2 0 0 2 2 2 0 Putative zinc-finger MFS_1 PF07690.16 EAU83827.2 - 2.2e-27 95.9 25.2 3.3e-27 95.3 25.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EAU83827.2 - 8.5 4.5 7.1 0.6 8.3 2.0 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family eIF-5_eIF-2B PF01873.17 EAU83828.2 - 1.8e-40 137.5 0.3 3.1e-40 136.7 0.3 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 EAU83828.2 - 0.0035 16.8 0.1 0.0071 15.8 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.15 EAU83828.2 - 0.011 15.6 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.12 EAU83828.2 - 0.022 14.5 0.1 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 EAU83828.2 - 1.3 9.4 5.1 8.5 6.8 0.0 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain NT-C2 PF10358.9 EAU83829.1 - 1.1e-13 51.2 0.0 4.1e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Nop25 PF09805.9 EAU83829.1 - 3.6 8.0 7.6 3.1 8.2 2.8 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) CDH-cyt PF16010.5 EAU83830.2 - 5.1e-09 36.1 0.7 7.7e-05 22.5 0.1 2.3 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase DUF1727 PF08353.10 EAU83830.2 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) LRR_4 PF12799.7 EAU83831.1 - 0.00041 20.7 3.9 3.6 8.1 0.2 5.8 6 1 0 6 6 6 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU83831.1 - 0.019 14.8 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 EAU83832.1 - 2.3e-05 24.2 8.3 4.4e-05 23.3 6.1 2.7 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU83832.1 - 0.89 10.1 4.3 90 3.7 0.1 4.5 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EAU83832.1 - 9.7 6.2 9.5 7.6 6.5 0.2 4.1 5 0 0 5 5 5 0 F-box domain MFS_1 PF07690.16 EAU83833.2 - 5.9e-16 58.3 44.1 5.1e-12 45.4 34.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrophobin PF01185.18 EAU83834.1 - 1.2e-19 70.7 12.0 1.5e-19 70.4 12.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ribosomal_L27e PF01777.18 EAU83835.1 - 3.2e-37 126.8 2.9 4.6e-37 126.2 2.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EAU83835.1 - 0.0047 16.8 0.4 0.012 15.6 0.4 1.8 1 0 0 1 1 1 1 KOW motif Nup54 PF13874.6 EAU83836.1 - 1.7e-32 112.5 0.2 1.7e-32 112.5 0.2 2.1 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EAU83836.1 - 8.1e-25 87.5 155.0 3.7e-10 40.5 46.8 5.4 1 1 3 5 5 5 5 Nucleoporin FG repeat region Nup54_C PF18437.1 EAU83836.1 - 0.015 15.2 3.0 0.015 15.2 3.0 3.7 4 1 0 4 4 4 0 Nup54 C-terminal interacting domain HWE_HK PF07536.14 EAU83836.1 - 0.05 14.3 1.4 0.05 14.3 1.4 1.8 2 0 0 2 2 2 0 HWE histidine kinase TPR_10 PF13374.6 EAU83838.2 - 2.6e-70 230.6 4.7 1e-07 31.6 0.0 12.0 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.6 EAU83838.2 - 1.9e-30 105.0 12.4 0.13 12.5 0.0 11.0 9 1 1 10 10 10 8 Tetratricopeptide repeat CHAT PF12770.7 EAU83838.2 - 3.1e-27 95.7 0.0 5.5e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.6 EAU83838.2 - 1.2e-16 59.8 8.0 2.6 8.6 0.0 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat DUF4404 PF14357.6 EAU83838.2 - 1.2e-06 29.0 2.6 1.2 9.8 0.0 6.4 4 2 1 6 6 6 2 Domain of unknown function (DUF4404) MAGI_u1 PF16663.5 EAU83838.2 - 0.00011 22.2 0.0 2.5e+02 1.8 0.0 8.2 10 0 0 10 10 10 0 Unstructured region on MAGI CNDH2_M PF16869.5 EAU83838.2 - 0.0058 17.3 10.5 20 5.9 0.0 6.7 2 1 6 8 8 8 0 PF16858 Peptidase_C25 PF01364.18 EAU83838.2 - 0.11 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 TPR_1 PF00515.28 EAU83838.2 - 0.57 10.1 37.3 34 4.5 0.0 13.5 15 0 0 15 15 15 0 Tetratricopeptide repeat ATP-synt PF00231.19 EAU83841.2 - 2.9e-77 260.1 3.8 3.5e-77 259.8 3.8 1.1 1 0 0 1 1 1 1 ATP synthase WD40 PF00400.32 EAU83842.1 - 4.2e-23 81.2 2.6 5.4e-05 23.9 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU83842.1 - 6.7e-12 45.6 0.0 0.0054 17.0 0.0 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAU83842.1 - 3.3e-05 23.8 0.1 0.32 10.9 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EAU83842.1 - 0.00061 19.7 0.3 0.29 11.1 0.1 4.0 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 EAU83842.1 - 0.003 16.7 0.0 1 8.3 0.0 3.0 2 1 0 3 3 3 1 Coatomer WD associated region C1-set PF07654.15 EAU83844.1 - 0.0024 18.2 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin C1-set domain TraC PF07820.12 EAU83845.2 - 0.23 11.8 1.3 0.72 10.2 1.3 1.9 1 0 0 1 1 1 0 TraC-like protein Fungal_trans_2 PF11951.8 EAU83846.1 - 0.1 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Peptidase_C98 PF15499.6 EAU83846.1 - 0.2 11.1 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CDH-cyt PF16010.5 EAU83849.2 - 3.2e-43 147.5 0.1 6.2e-43 146.6 0.0 1.5 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Methyltransf_22 PF13383.6 EAU83849.2 - 0.0057 16.2 0.0 0.015 14.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ribosomal_L28 PF00830.19 EAU83850.1 - 1.4e-23 82.9 0.6 2.3e-23 82.1 0.6 1.4 1 0 0 1 1 1 1 Ribosomal L28 family ELL PF10390.9 EAU83850.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Alginate_lyase PF05426.12 EAU83852.2 - 2e-39 135.8 0.9 1e-37 130.2 0.4 2.3 1 1 1 2 2 2 2 Alginate lyase DUF5127 PF17168.4 EAU83852.2 - 0.052 13.3 1.1 0.098 12.4 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) NTP_transf_9 PF04248.12 EAU83852.2 - 0.18 11.7 0.6 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF427) COesterase PF00135.28 EAU83853.2 - 1.4e-75 255.2 0.0 1.7e-75 254.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU83853.2 - 6.1e-06 26.2 0.5 3.8e-05 23.6 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold CDH-cyt PF16010.5 EAU83855.1 - 2.7e-42 144.5 0.3 5.2e-42 143.6 0.3 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CBM_1 PF00734.18 EAU83855.1 - 2.2e-11 43.5 8.5 6e-11 42.1 8.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DOMON PF03351.17 EAU83855.1 - 0.00022 21.4 0.0 0.00067 19.9 0.0 1.8 1 0 0 1 1 1 1 DOMON domain PD40 PF07676.12 EAU83855.1 - 0.021 14.8 0.2 0.16 12.0 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat NHL PF01436.21 EAU83855.1 - 0.11 12.6 0.1 16 5.8 0.0 3.4 3 0 0 3 3 3 0 NHL repeat CDH-cyt PF16010.5 EAU83856.1 - 3.7e-45 153.8 0.2 6.2e-45 153.1 0.2 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase CBM_1 PF00734.18 EAU83856.1 - 5.3e-12 45.5 8.8 1.6e-11 43.9 8.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain PD40 PF07676.12 EAU83856.1 - 0.018 15.0 0.1 0.44 10.6 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DOMON PF03351.17 EAU83856.1 - 0.02 15.1 0.1 0.079 13.2 0.0 2.0 2 0 0 2 2 2 0 DOMON domain Glyco_hydro_61 PF03443.14 EAU83857.1 - 3.7e-62 209.9 0.0 4.2e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CDC45 PF02724.14 EAU83858.1 - 0.13 10.6 0.4 0.13 10.6 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CAP_N PF01213.19 EAU83858.1 - 1.6 8.2 13.6 0.67 9.4 3.6 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF3884 PF13024.6 EAU83860.1 - 0.0039 16.7 0.0 3.5 7.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3884) Rap1a PF18602.1 EAU83860.1 - 0.017 15.4 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Rap1a immunity proteins DUF765 PF05570.11 EAU83860.1 - 0.027 14.7 7.4 1.4 9.2 0.3 2.7 3 0 0 3 3 3 0 Circovirus protein of unknown function (DUF765) Involucrin_N PF10583.9 EAU83860.1 - 0.056 14.0 0.3 9.9 6.8 0.0 2.8 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus Dicer_N PF17895.1 EAU83860.1 - 0.066 13.1 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Giardia Dicer N-terminal domain DUF3787 PF12655.7 EAU83860.1 - 0.15 12.0 3.4 6.1 6.9 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) Rtt106_N PF18215.1 EAU83860.1 - 0.19 11.5 0.2 9.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain SipA PF09052.10 EAU83860.1 - 0.26 10.9 1.6 4.2 6.9 0.1 2.2 2 0 0 2 2 2 0 SipA N-terminal domain DUF3564 PF12087.8 EAU83860.1 - 1.9 8.5 6.2 8.4 6.4 0.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3564) Peroxidase_2 PF01328.17 EAU83861.1 - 2.2e-50 171.8 0.0 3.3e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Metal_resist PF13801.6 EAU83862.1 - 0.0052 17.0 0.5 0.8 9.9 0.0 2.4 2 0 0 2 2 2 2 Heavy-metal resistance COG4 PF08318.12 EAU83862.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 COG4 transport protein Phage_ABA_S PF18066.1 EAU83862.1 - 0.19 12.5 0.0 23 5.8 0.0 2.2 2 0 0 2 2 2 0 Phage ABA sandwich domain Peptidase_M43 PF05572.13 EAU83863.2 - 6.6e-19 68.3 0.0 9.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU83863.2 - 0.0071 16.5 0.0 0.014 15.6 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 WT1 PF02165.15 EAU83863.2 - 0.017 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Wilm's tumour protein Reprolysin_3 PF13582.6 EAU83863.2 - 0.019 15.5 0.0 0.042 14.4 0.0 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU83863.2 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EAU83863.2 - 0.093 11.7 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Glyco_hydro_5_C PF18564.1 EAU83864.2 - 5.2e-24 84.6 0.0 1.1e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EAU83864.2 - 1.6e-11 44.2 0.0 4.4e-06 26.3 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) GWT1 PF06423.12 EAU83865.2 - 3e-40 137.8 0.0 1.1e-39 135.9 0.0 2.0 2 0 0 2 2 2 1 GWT1 CDH-cyt PF16010.5 EAU83866.2 - 5.7e-22 78.3 0.0 1.1e-14 54.5 0.0 2.3 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase CBM_1 PF00734.18 EAU83866.2 - 3.2e-10 39.8 5.2 3.2e-10 39.8 5.2 2.2 3 0 0 3 3 3 1 Fungal cellulose binding domain SBBP PF06739.11 EAU83866.2 - 0.18 11.8 1.3 36 4.5 0.1 4.2 4 0 0 4 4 4 0 Beta-propeller repeat GST_N_3 PF13417.6 EAU83867.1 - 2e-10 40.9 0.0 3.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU83867.1 - 1.4e-09 37.8 0.1 2.8e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU83867.1 - 3.9e-05 23.8 0.0 8.1e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAU83867.1 - 4.3e-05 23.7 0.0 7.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EAU83867.1 - 0.001 19.3 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU83867.1 - 0.0063 16.7 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EAU83867.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Ank_2 PF12796.7 EAU83868.2 - 1.8e-98 323.3 9.5 9.9e-17 61.3 0.1 9.4 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.30 EAU83868.2 - 1.5e-89 290.8 17.1 2.4e-07 30.9 0.0 17.6 15 2 1 16 16 16 15 Ankyrin repeat Ank_3 PF13606.6 EAU83868.2 - 6.1e-86 272.0 6.2 6.1e-05 23.1 0.0 17.6 16 1 1 17 17 17 15 Ankyrin repeat Ank_4 PF13637.6 EAU83868.2 - 1.2e-65 217.1 24.9 8e-07 29.5 0.1 14.9 3 2 12 15 15 15 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU83868.2 - 9.5e-53 175.6 33.2 2.2e-07 31.0 0.2 12.3 5 3 9 14 14 14 14 Ankyrin repeats (many copies) UBA_4 PF14555.6 EAU83868.2 - 0.00034 20.4 0.2 38 4.2 0.0 5.4 5 0 0 5 5 5 0 UBA-like domain Nitro_FeMo-Co PF02579.17 EAU83868.2 - 0.005 17.1 0.5 35 4.8 0.0 4.5 3 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor BRCA-2_helical PF09169.10 EAU83868.2 - 0.015 14.9 1.1 9.1 5.9 0.0 4.1 4 0 0 4 4 4 0 BRCA2, helical NACHT PF05729.12 EAU83868.2 - 0.067 13.1 0.1 0.22 11.4 0.1 1.8 1 0 0 1 1 1 0 NACHT domain E3_binding PF02817.17 EAU83868.2 - 0.26 11.6 1.3 26 5.3 0.0 4.4 4 0 0 4 4 3 0 e3 binding domain WGG PF10273.9 EAU83868.2 - 0.67 10.7 14.0 29 5.4 0.0 7.5 10 1 0 10 10 8 0 Pre-rRNA-processing protein TSR2 Ank_2 PF12796.7 EAU83870.2 - 1.2e-48 163.5 2.8 4.4e-15 56.0 0.0 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU83870.2 - 3.6e-31 103.7 2.4 0.0056 17.1 0.0 9.4 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 EAU83870.2 - 4.2e-27 93.4 16.1 0.0042 17.5 0.1 9.3 8 1 1 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 EAU83870.2 - 2.2e-25 88.4 12.3 1.9e-10 40.8 0.1 7.6 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU83870.2 - 5.3e-21 74.7 6.7 3.6e-05 24.2 0.1 7.4 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Plavaka PF18759.1 EAU83872.2 - 5e-11 42.4 0.0 4.8e-10 39.2 0.0 2.2 1 1 0 1 1 1 1 Plavaka transposase Epimerase PF01370.21 EAU83881.2 - 3.6e-15 56.1 0.1 8.1e-15 54.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAU83881.2 - 3.1e-11 42.8 0.0 2.1e-09 36.8 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAU83881.2 - 8.5e-09 35.3 0.1 4.4e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAU83881.2 - 1e-08 35.3 0.0 2.7e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EAU83881.2 - 1.5e-06 28.0 0.0 3.3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EAU83881.2 - 4.8e-05 22.6 0.0 0.00045 19.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EAU83881.2 - 0.00011 21.8 0.2 0.00041 19.9 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU83881.2 - 0.00062 19.7 0.0 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 KR domain HMG_box PF00505.19 EAU83886.2 - 3.2e-11 43.5 0.0 5.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU83886.2 - 0.00073 20.1 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 EAU83886.2 - 0.04 13.9 0.1 0.072 13.1 0.1 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 MCU PF04678.13 EAU83887.2 - 5.8e-36 124.2 0.1 8.9e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2721 PF11026.8 EAU83887.2 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Phage_holin_3_6 PF07332.11 EAU83887.2 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Abhydrolase_6 PF12697.7 EAU83888.2 - 2.1e-07 31.8 0.7 2.4e-07 31.6 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU83888.2 - 0.0017 18.0 0.0 0.0047 16.6 0.0 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ost5 PF05251.12 EAU83889.1 - 1.4 9.2 12.3 0.25 11.6 5.7 2.3 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 LRR_4 PF12799.7 EAU83890.2 - 0.29 11.6 8.5 9.3 6.8 1.4 5.3 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) Hexokinase_2 PF03727.16 EAU83892.2 - 6e-85 284.5 0.0 7.8e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EAU83892.2 - 2.3e-67 226.8 0.0 3.1e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Ribosomal_L14 PF00238.19 EAU83893.1 - 1.6e-46 157.3 3.0 1.8e-46 157.2 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Fungal_trans PF04082.18 EAU83894.2 - 4.2e-11 42.4 0.0 6.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU83894.2 - 7.5e-07 29.2 9.4 1.6e-06 28.2 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sin3_corepress PF08295.12 EAU83894.2 - 0.02 14.9 0.7 0.066 13.3 0.2 2.0 2 0 0 2 2 2 0 Sin3 family co-repressor TB2_DP1_HVA22 PF03134.19 EAU83895.2 - 1.4e-27 95.4 6.2 2.2e-27 94.8 6.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family M PF02370.16 EAU83895.2 - 0.074 13.6 1.1 0.16 12.6 1.1 1.6 1 0 0 1 1 1 0 M protein repeat Sugarporin_N PF11471.8 EAU83895.2 - 0.59 10.1 3.8 0.27 11.2 1.0 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Ribonuclease PF00545.20 EAU83898.2 - 0.0023 18.7 0.3 0.004 17.9 0.3 1.3 1 0 0 1 1 1 1 ribonuclease EHN PF06441.12 EAU83899.2 - 1.5e-34 118.6 3.4 2.5e-33 114.7 0.0 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EAU83899.2 - 6.7e-19 68.5 0.4 1.1e-18 67.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU83899.2 - 0.0039 17.8 10.5 0.0039 17.8 10.5 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF2157 PF09925.9 EAU83900.2 - 0.052 13.3 0.2 0.052 13.3 0.2 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) UcrQ PF02939.16 EAU83901.1 - 1.8e-27 95.1 1.3 2.3e-27 94.7 1.3 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 EAU83901.1 - 0.0048 17.3 0.1 0.0067 16.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 CBM_1 PF00734.18 EAU83902.1 - 2.6e-12 46.5 16.4 2.6e-12 46.5 16.4 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAU83902.1 - 0.0006 20.0 3.3 0.0013 18.9 3.3 1.6 1 0 0 1 1 1 1 Toxin 7 MSA-2c PF12238.8 EAU83902.1 - 2.8 7.9 8.6 4.1 7.3 8.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c F-box-like PF12937.7 EAU83905.1 - 0.0046 16.8 0.0 0.018 14.9 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU83906.1 - 0.02 14.8 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EAU83906.1 - 0.057 13.3 1.4 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 F-box domain ArfGap PF01412.18 EAU83907.2 - 1.2e-39 135.1 0.6 1.7e-39 134.5 0.6 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf F-box-like PF12937.7 EAU83908.2 - 2.6e-05 24.0 0.0 5.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like LEM PF03020.15 EAU83908.2 - 0.13 11.9 0.2 0.28 10.8 0.2 1.5 1 0 0 1 1 1 0 LEM domain Glyco_transf_90 PF05686.12 EAU83909.1 - 1.5e-16 60.3 1.2 5.2e-08 32.2 0.0 3.9 4 0 0 4 4 4 3 Glycosyl transferase family 90 GDP_Man_Dehyd PF16363.5 EAU83910.1 - 3.2e-159 529.7 0.0 3.7e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EAU83910.1 - 2.1e-73 246.7 0.0 3.1e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EAU83910.1 - 0.0037 16.4 0.0 0.0058 15.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EAU83910.1 - 0.016 14.4 0.0 0.051 12.7 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 EAU83910.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 EAU83911.2 - 5.5e-53 179.9 0.0 1.1e-52 179.0 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAU83911.2 - 1.6e-14 54.1 0.1 9.1e-14 51.6 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAU83911.2 - 1.3e-05 24.5 0.2 0.0019 17.4 0.2 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAU83911.2 - 0.0002 20.5 0.0 0.00044 19.4 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EAU83911.2 - 0.0043 16.1 0.0 0.007 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PAPS_reduct PF01507.19 EAU83912.2 - 1.2e-19 71.0 0.2 6.2e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ETX_MTX2 PF03318.13 EAU83913.2 - 2.2e-07 30.9 5.1 3.8e-07 30.1 5.1 1.4 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 EAU83913.2 - 9.1e-05 21.8 0.1 0.00014 21.2 0.1 1.2 1 0 0 1 1 1 1 Aerolysin toxin Mre11_DNA_bind PF04152.14 EAU83914.2 - 1.3e-52 178.5 0.2 1.3e-52 178.5 0.2 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EAU83914.2 - 8.5e-12 46.0 0.4 1.6e-11 45.1 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Prp18 PF02840.15 EAU83914.2 - 0.13 12.3 1.6 0.39 10.7 1.5 1.8 1 1 0 1 1 1 0 Prp18 domain Stm1_N PF09598.10 EAU83914.2 - 0.7 10.8 27.4 3.2 8.7 13.8 3.0 2 0 0 2 2 2 0 Stm1 TPT PF03151.16 EAU83915.2 - 9.3e-18 64.6 20.5 1.1e-17 64.3 20.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAU83915.2 - 5.6e-08 33.0 39.9 8.8e-06 25.9 14.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family p450 PF00067.22 EAU83916.2 - 2.2e-44 152.0 0.0 2.6e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alpha_kinase PF02816.18 EAU83917.2 - 6e-08 33.0 0.0 9.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family CxC5 PF18718.1 EAU83918.2 - 1.9e-32 111.8 3.0 3.7e-32 110.9 3.0 1.5 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EAU83918.2 - 3.2e-27 94.6 7.9 8.4e-27 93.2 7.9 1.7 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases p450 PF00067.22 EAU83918.2 - 1.8e-15 56.6 0.0 2.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Erythro-docking PF09277.11 EAU83918.2 - 0.17 11.8 0.2 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 Erythronolide synthase, docking YbjM PF11045.8 EAU83919.2 - 0.18 12.0 0.1 0.25 11.5 0.1 1.1 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae SYF2 PF08231.12 EAU83920.1 - 5.8e-59 199.0 15.2 5.8e-59 199.0 15.2 2.7 2 1 1 3 3 3 1 SYF2 splicing factor ALS2CR8 PF15299.6 EAU83920.1 - 3.9 7.3 10.5 5.7 6.8 7.8 2.3 2 1 0 2 2 2 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 TPT PF03151.16 EAU83921.2 - 1.8e-35 122.7 9.7 3.7e-26 92.1 1.2 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 EAU83921.2 - 1.8e-07 30.7 10.7 5.4e-05 22.5 1.1 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 EAU83921.2 - 0.0017 18.6 24.9 0.019 15.2 4.0 3.5 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 EAU83922.2 - 1.8e-37 129.3 9.5 2.8e-28 99.1 3.5 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 EAU83922.2 - 6.7e-08 32.1 6.7 1.6e-05 24.3 0.9 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 EAU83922.2 - 4.4e-05 23.7 27.0 0.0014 18.8 9.5 3.2 3 1 1 4 4 4 2 EamA-like transporter family Saf_2TM PF18303.1 EAU83922.2 - 0.37 10.4 2.2 1.1 8.8 0.1 2.5 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain DUF908 PF06012.12 EAU83922.2 - 0.54 9.6 7.1 4.4 6.6 2.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) SHMT PF00464.19 EAU83923.1 - 3e-173 576.0 0.0 3.5e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EAU83923.1 - 0.0072 15.6 0.0 0.021 14.1 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase zf-C3HC4_2 PF13923.6 EAU83924.2 - 6.5e-08 32.3 1.9 6.5e-08 32.3 1.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU83924.2 - 4.2e-06 26.7 3.3 4.2e-06 26.7 3.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAU83924.2 - 1.1e-05 25.2 1.5 1.1e-05 25.2 1.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU83924.2 - 2.1e-05 24.7 15.4 3.1e-05 24.2 1.5 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 EAU83924.2 - 9e-05 22.6 2.3 9e-05 22.6 2.3 2.5 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EAU83924.2 - 0.00011 22.0 15.5 0.0012 18.6 2.1 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU83924.2 - 0.00025 20.9 1.5 0.00025 20.9 1.5 3.3 3 0 0 3 3 3 1 zinc-RING finger domain Laminin_EGF PF00053.24 EAU83924.2 - 0.005 16.9 2.0 0.015 15.4 2.0 1.7 1 0 0 1 1 1 1 Laminin EGF domain zf-RING_6 PF14835.6 EAU83924.2 - 0.0079 16.0 0.2 0.0079 16.0 0.2 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein FOXP-CC PF16159.5 EAU83924.2 - 0.081 13.6 0.7 0.16 12.6 0.7 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-RING_10 PF16685.5 EAU83924.2 - 0.23 11.6 2.7 0.58 10.3 2.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EAU83924.2 - 1.6 9.1 5.5 14 6.0 0.8 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain ATPase_2 PF01637.18 EAU83925.2 - 2.5e-12 47.2 0.0 5.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EAU83925.2 - 6.2e-06 26.7 0.7 3.1e-05 24.4 0.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU83925.2 - 0.00017 21.8 0.1 0.07 13.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain ResIII PF04851.15 EAU83925.2 - 0.0069 16.4 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 EAU83925.2 - 0.013 15.9 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.9 EAU83925.2 - 0.028 13.2 0.0 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA12 protein AAA_11 PF13086.6 EAU83925.2 - 0.14 11.9 0.5 0.86 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Smg4_UPF3 PF03467.15 EAU83926.1 - 4e-52 176.7 1.2 4e-52 176.7 1.2 2.7 4 0 0 4 4 4 1 Smg-4/UPF3 family DUF4121 PF13497.6 EAU83926.1 - 0.074 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) COesterase PF00135.28 EAU83928.2 - 1.6e-79 268.1 0.0 2.1e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU83928.2 - 2.1e-06 27.8 2.9 1.7e-05 24.7 2.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU83928.2 - 0.0042 16.6 0.7 0.0073 15.8 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lectin_C PF00059.21 EAU83928.2 - 0.1 13.4 0.1 0.55 11.0 0.0 2.2 3 0 0 3 3 3 0 Lectin C-type domain Spt5-NGN PF03439.13 EAU83929.2 - 2.5e-21 75.4 0.0 5.2e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EAU83929.2 - 1.7e-16 61.0 10.4 1.7e-16 61.0 10.4 3.5 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EAU83929.2 - 3.3e-14 52.3 23.3 0.00012 21.9 0.3 7.1 7 0 0 7 7 7 4 KOW motif CTD PF12815.7 EAU83929.2 - 1e-09 38.8 58.5 1.9e-06 28.3 15.6 4.1 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 F-protein PF00469.20 EAU83929.2 - 1.9 8.0 8.2 10 5.6 6.6 2.4 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Epimerase PF01370.21 EAU83930.1 - 2.7e-14 53.2 0.0 1e-11 44.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAU83930.1 - 1.9e-11 43.5 0.0 6.6e-10 38.4 0.0 2.1 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EAU83930.1 - 3.1e-11 43.5 0.0 5.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EAU83930.1 - 5.5e-09 35.9 0.1 2.4e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EAU83930.1 - 2.1e-05 23.9 0.0 0.00032 20.0 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EAU83930.1 - 0.0012 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EAU83930.1 - 0.0033 16.9 0.0 0.0082 15.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EAU83930.1 - 0.045 12.9 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RRM_1 PF00076.22 EAU83930.1 - 0.2 11.5 0.1 0.77 9.6 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DJ-1_PfpI PF01965.24 EAU83931.1 - 1.5e-36 125.7 0.0 1.8e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EAU83931.1 - 0.019 14.7 0.0 0.059 13.1 0.0 1.7 2 0 0 2 2 2 0 ThiJ/PfpI family-like GATase_3 PF07685.14 EAU83931.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AIM5 PF17050.5 EAU83932.2 - 2.1e-07 31.6 0.0 2.1e-07 31.6 0.0 2.4 3 0 0 3 3 3 1 Altered inheritance of mitochondria 5 DUF543 PF04418.12 EAU83933.1 - 5.4e-28 96.8 0.2 6.1e-28 96.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-NOSIP PF15906.5 EAU83936.2 - 3e-11 43.3 0.2 3e-11 43.3 0.2 1.7 2 0 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 EAU83936.2 - 3.5e-11 42.8 16.4 3.1e-07 30.2 6.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EAU83936.2 - 1.4e-09 37.8 14.4 6.4e-07 29.0 1.3 2.8 2 1 1 3 3 3 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 EAU83936.2 - 7.6e-08 32.1 17.9 0.00013 21.7 9.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU83936.2 - 2.6e-07 30.9 17.5 0.00013 22.3 8.8 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 EAU83936.2 - 1.4e-06 28.2 15.6 0.00098 19.1 0.8 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 EAU83936.2 - 2.7e-06 27.2 20.6 1.2e-05 25.2 9.5 2.6 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 EAU83936.2 - 2e-05 24.3 20.2 0.013 15.4 10.4 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU83936.2 - 0.00017 21.4 21.1 0.03 14.2 9.8 3.2 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAU83936.2 - 0.00078 19.5 15.1 0.025 14.7 1.2 2.7 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING CALM_bind PF16025.5 EAU83936.2 - 0.019 15.4 0.2 3.4 8.2 0.2 2.3 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding zf-ribbon_3 PF13248.6 EAU83936.2 - 0.16 11.4 0.1 0.16 11.4 0.1 3.0 4 0 0 4 4 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EAU83936.2 - 0.22 11.5 14.4 0.66 10.0 6.5 2.4 2 0 0 2 2 2 0 zinc-ribbons FYVE PF01363.21 EAU83936.2 - 0.28 11.3 10.7 0.24 11.5 3.0 2.9 2 1 0 2 2 2 0 FYVE zinc finger Plasmid_RAQPRD PF09686.10 EAU83936.2 - 0.43 10.8 3.6 1.1 9.5 3.6 1.7 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Borrelia_P83 PF05262.11 EAU83936.2 - 4.3 5.7 6.3 6.6 5.1 6.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DZR PF12773.7 EAU83936.2 - 6.8 6.8 17.2 3.2 7.8 8.7 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-P11 PF03854.14 EAU83936.2 - 8.7 6.1 16.7 14 5.5 1.8 2.7 2 1 0 2 2 2 0 P-11 zinc finger DUF3833 PF12915.7 EAU83937.2 - 0.0062 16.1 0.2 0.03 13.9 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3833) SnoaL_2 PF12680.7 EAU83937.2 - 0.022 15.4 0.0 0.052 14.2 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain S_tail_recep_bd PF14928.6 EAU83937.2 - 0.32 11.6 3.0 16 6.2 0.0 2.3 1 1 0 2 2 2 0 Short tail fibre protein receptor-binding domain Arabinose_Iso_C PF11762.8 EAU83938.2 - 0.11 12.3 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain SCHIP-1 PF10148.9 EAU83938.2 - 0.22 11.1 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 N-glycanase_N PF09112.10 EAU83939.2 - 0.067 13.0 0.0 0.077 12.8 0.0 1.1 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal Sof1 PF04158.14 EAU83940.1 - 1.4e-27 95.7 6.5 1.4e-27 95.7 6.5 2.1 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 EAU83940.1 - 8e-22 77.1 11.3 2.8e-07 31.1 0.2 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU83940.1 - 5.5e-06 26.6 0.1 1.4 9.3 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RGS PF00615.19 EAU83942.1 - 0.00032 20.9 0.0 0.00055 20.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Lactamase_B_2 PF12706.7 EAU83943.2 - 2.8e-05 23.7 0.5 0.00021 20.9 0.5 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAU83943.2 - 0.41 10.6 3.0 1.8 8.5 3.0 2.0 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DMAP_binding PF06464.11 EAU83943.2 - 0.6 10.9 5.7 3.2 8.6 0.1 3.7 3 0 0 3 3 3 0 DMAP1-binding Domain DUF4298 PF14131.6 EAU83944.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Hydin_ADK PF17213.3 EAU83944.1 - 0.16 12.3 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain HAUS6_N PF14661.6 EAU83944.1 - 0.22 11.1 0.9 0.36 10.4 0.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Vps26 PF03643.15 EAU83945.1 - 2.6e-123 410.4 5.1 1.7e-122 407.7 5.1 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.22 EAU83945.1 - 0.0054 17.2 0.3 0.21 12.1 0.1 2.8 2 1 1 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EAU83945.1 - 0.049 13.7 1.1 0.33 11.0 0.5 2.6 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain AAA_5 PF07728.14 EAU83946.2 - 1.2e-68 229.4 0.0 1e-28 100.0 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 EAU83946.2 - 0.015 15.6 0.1 2.4 8.5 0.1 2.6 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal AAA_16 PF13191.6 EAU83946.2 - 0.026 14.9 2.6 5.9 7.2 0.0 4.2 4 1 1 5 5 5 0 AAA ATPase domain Phage_holin_3_6 PF07332.11 EAU83947.1 - 2.8 8.0 18.6 0.37 10.8 1.5 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NAD_binding_6 PF08030.12 EAU83948.1 - 4e-37 127.7 0.0 6.4e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAU83948.1 - 3.4e-22 78.6 0.0 7.4e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EAU83948.1 - 5.6e-18 65.2 10.5 5.6e-18 65.2 10.5 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EAU83948.1 - 0.071 13.8 0.1 0.48 11.1 0.1 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Saf_2TM PF18303.1 EAU83948.1 - 0.46 10.1 2.8 1.6 8.3 0.3 2.4 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain PNP_UDP_1 PF01048.20 EAU83949.1 - 3e-38 131.4 0.0 3.8e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Sds3 PF08598.11 EAU83950.2 - 1.2e-20 74.5 13.7 1.2e-20 74.5 13.7 3.3 2 1 1 3 3 3 1 Sds3-like Fungal_trans PF04082.18 EAU83952.2 - 2.6e-34 118.5 0.0 5.6e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU83952.2 - 0.0031 17.6 12.9 0.0059 16.7 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2013 PF09431.10 EAU83953.2 - 5.2e-43 146.5 2.4 1.2e-42 145.3 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Amidase PF01425.21 EAU83954.1 - 4.9e-107 358.7 0.0 5.8e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Amidase CLN6 PF15156.6 EAU83954.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 MFS_1 PF07690.16 EAU83958.2 - 2.9e-41 141.6 25.1 3.9e-41 141.2 25.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 EAU83958.2 - 0.16 11.2 19.5 0.01 15.2 5.4 2.7 2 1 0 2 2 2 0 Sporulation factor SpoIIGA VIT1 PF01988.19 EAU83958.2 - 6.5 6.6 20.7 0.46 10.3 1.2 4.2 1 1 1 4 4 4 0 VIT family MFS_1 PF07690.16 EAU83959.1 - 9.6e-38 130.0 37.9 1.3e-37 129.5 37.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M20 PF01546.28 EAU83960.1 - 9.2e-10 38.6 0.1 1.4e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAU83960.1 - 7.5e-07 29.0 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain AAA_11 PF13086.6 EAU83962.2 - 1.4e-60 205.3 0.0 1.4e-60 205.3 0.0 2.1 2 1 1 3 3 2 1 AAA domain AAA_12 PF13087.6 EAU83962.2 - 1.8e-57 194.2 0.0 2.9e-57 193.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU83962.2 - 8.7e-09 35.5 0.1 0.01 15.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EAU83962.2 - 1.6e-07 31.3 0.1 0.0063 16.3 0.7 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EAU83962.2 - 9.8e-06 26.0 0.1 0.00021 21.6 0.1 3.0 2 2 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EAU83962.2 - 0.00089 19.0 0.1 0.026 14.3 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 EAU83962.2 - 0.0015 18.6 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EAU83962.2 - 0.0059 15.9 0.3 0.22 10.7 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) DUF4641 PF15483.6 EAU83962.2 - 0.0077 15.4 1.2 0.0077 15.4 1.2 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4641) UvrD-helicase PF00580.21 EAU83962.2 - 0.12 11.8 0.0 2.2 7.7 0.0 2.3 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Spt5_N PF11942.8 EAU83962.2 - 2 9.5 12.0 0.64 11.0 8.0 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ApbA PF02558.16 EAU83963.1 - 2.4e-22 79.2 0.0 5.1e-22 78.1 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EAU83963.1 - 2e-19 70.0 0.0 1.9e-17 63.6 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.6 EAU83963.1 - 0.018 15.5 0.1 0.035 14.5 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Piwi PF02171.17 EAU83964.2 - 2.4e-80 270.0 0.0 3.7e-80 269.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EAU83964.2 - 1.9e-23 83.6 0.0 3.6e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EAU83964.2 - 9e-19 66.9 0.3 2.5e-18 65.5 0.3 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EAU83964.2 - 8.6e-15 54.7 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EAU83964.2 - 6.6e-12 45.6 0.1 1.9e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EAU83964.2 - 0.0014 18.8 0.0 0.0035 17.6 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute SBDS PF01172.18 EAU83968.1 - 3e-23 81.7 0.2 3.4e-23 81.5 0.2 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein EHN PF06441.12 EAU83969.2 - 1.6e-36 125.0 1.1 1.6e-34 118.5 0.0 2.4 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EAU83969.2 - 1.1e-17 64.6 0.0 1.7e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU83969.2 - 0.0041 17.7 4.9 0.0041 17.7 4.9 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family EST1_DNA_bind PF10373.9 EAU83974.2 - 3e-28 99.1 0.1 9.7e-28 97.4 0.1 1.9 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EAU83974.2 - 2.1e-23 83.5 1.8 6.1e-23 82.0 0.0 2.7 3 0 0 3 3 3 1 Telomerase activating protein Est1 DUF5572 PF17733.1 EAU83975.1 - 1.4e-19 69.6 0.9 3.2e-19 68.5 0.9 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF3480 PF11979.8 EAU83975.1 - 0.05 12.6 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) PrcB_C PF14343.6 EAU83975.1 - 0.17 12.1 0.6 0.31 11.2 0.1 1.7 2 0 0 2 2 2 0 PrcB C-terminal DEAD PF00270.29 EAU83976.2 - 1.1e-47 162.1 0.0 2.1e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU83976.2 - 5.6e-23 81.4 0.0 2.2e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAU83976.2 - 4.3e-15 55.7 0.0 1.9e-14 53.6 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAU83976.2 - 1.2e-05 25.3 0.0 5.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CLN3 PF02487.17 EAU83977.1 - 4e-130 434.5 0.4 4.7e-130 434.2 0.4 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EAU83977.1 - 0.22 10.4 21.8 0.98 8.3 21.8 2.2 1 1 0 1 1 1 0 Major Facilitator Superfamily UBM PF14377.6 EAU83979.2 - 0.047 13.1 0.0 0.16 11.5 0.0 2.0 1 0 0 1 1 1 0 Ubiquitin binding region Vac_Fusion PF02346.16 EAU83979.2 - 0.16 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Tropomyosin_1 PF12718.7 EAU83980.2 - 4.1e-06 27.0 1.7 0.088 13.0 0.1 2.4 1 1 1 2 2 2 2 Tropomyosin like HOOK PF05622.12 EAU83980.2 - 0.007 14.6 1.4 0.012 13.8 1.4 1.3 1 0 0 1 1 1 1 HOOK protein Tropomyosin PF00261.20 EAU83980.2 - 0.011 15.1 6.5 0.71 9.2 3.0 2.9 1 1 1 2 2 2 0 Tropomyosin Laminin_II PF06009.12 EAU83980.2 - 0.067 13.2 0.3 0.77 9.8 0.0 2.6 2 1 1 3 3 3 0 Laminin Domain II Sec34 PF04136.15 EAU83980.2 - 0.18 11.7 0.3 13 5.6 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family EzrA PF06160.12 EAU83980.2 - 0.2 9.8 0.0 0.55 8.3 0.0 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Nop14 PF04147.12 EAU83980.2 - 0.29 9.3 13.3 0.48 8.6 13.3 1.3 1 0 0 1 1 1 0 Nop14-like family GAS PF13851.6 EAU83980.2 - 0.43 9.9 2.2 1.7 7.9 1.3 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CDC45 PF02724.14 EAU83980.2 - 2.2 6.5 10.1 3.3 5.9 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.9 EAU83980.2 - 8.3 5.3 11.4 1 8.3 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DHR10 PF18595.1 EAU83980.2 - 8.3 6.5 9.3 2.5 8.2 0.7 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain HMG_box_2 PF09011.10 EAU83981.1 - 0.046 14.3 0.1 0.14 12.7 0.1 1.8 1 0 0 1 1 1 0 HMG-box domain Tet_JBP PF12851.7 EAU83986.2 - 3.9e-07 29.8 0.0 7.4e-06 25.5 0.0 2.0 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Spc7 PF08317.11 EAU83987.2 - 0.1 11.5 0.0 0.22 10.4 0.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Tet_JBP PF12851.7 EAU83988.1 - 6e-15 55.4 0.0 6.9e-12 45.4 0.0 2.2 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.7 EAU83989.2 - 3.5e-08 33.2 0.0 5.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HMG_box_2 PF09011.10 EAU83991.2 - 0.00013 22.5 0.2 0.00013 22.5 0.2 2.8 2 0 0 2 2 2 1 HMG-box domain Zn_clus PF00172.18 EAU83992.1 - 0.066 13.3 12.0 0.1 12.7 12.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CM_2 PF01817.21 EAU83997.2 - 7.5e-16 58.2 0.1 9.3e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Dor1 PF04124.12 EAU83997.2 - 0.019 13.6 0.1 0.023 13.4 0.1 1.0 1 0 0 1 1 1 0 Dor1-like family G-alpha PF00503.20 EAU83998.2 - 2.1e-106 356.1 0.0 2.5e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU83998.2 - 9.7e-08 31.7 0.5 1.9e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MIP PF00230.20 EAU83999.1 - 9.1e-54 182.6 11.6 1.2e-53 182.2 11.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.20 EAU83999.1 - 0.0015 18.7 9.1 0.0065 16.7 3.1 2.5 2 0 0 2 2 2 2 EamA-like transporter family Complex1_LYR PF05347.15 EAU84000.1 - 3.3e-16 59.1 0.2 4.2e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EAU84000.1 - 0.024 15.4 0.4 0.026 15.2 0.4 1.3 1 1 0 1 1 1 0 Complex1_LYR-like DUF5481 PF17578.2 EAU84000.1 - 0.031 14.7 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5481) Complex1_LYR_1 PF13232.6 EAU84000.1 - 0.037 14.6 0.0 0.27 11.9 0.0 1.8 1 1 1 2 2 2 0 Complex1_LYR-like PKHD_C PF18331.1 EAU84000.1 - 0.13 12.4 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain HIG_1_N PF04588.13 EAU84001.1 - 2.2e-21 75.8 0.5 4e-21 75.0 0.5 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region COX16 PF14138.6 EAU84001.1 - 0.083 13.4 0.5 0.15 12.6 0.5 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Urm1 PF09138.11 EAU84002.1 - 3.9e-34 116.9 0.2 4.8e-33 113.4 0.2 1.9 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EAU84002.1 - 6.7e-06 26.7 0.0 9.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ThiS family ThiS-like PF14453.6 EAU84002.1 - 0.1 12.6 0.1 0.35 11.0 0.0 1.9 2 0 0 2 2 2 0 ThiS-like ubiquitin TrkA_C PF02080.21 EAU84002.1 - 0.19 11.6 0.6 0.71 9.8 0.1 2.2 2 1 1 3 3 3 0 TrkA-C domain Ribosomal_S30 PF04758.14 EAU84003.2 - 3.6e-29 100.7 5.9 6.1e-29 100.0 5.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S30 zf-C2H2 PF00096.26 EAU84003.2 - 4.4e-06 26.9 4.3 0.01 16.2 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU84003.2 - 0.00013 22.5 3.6 0.06 14.2 0.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EAU84003.2 - 0.00025 21.3 2.2 0.0029 17.9 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SR-25 PF10500.9 EAU84003.2 - 0.0023 17.6 3.5 0.0029 17.3 3.5 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-C2H2_6 PF13912.6 EAU84003.2 - 0.0025 17.8 0.8 0.0025 17.8 0.8 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU84003.2 - 0.0026 18.0 2.6 0.006 16.8 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EAU84003.2 - 0.0037 17.6 4.3 0.28 11.7 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double domain IMUP PF15761.5 EAU84003.2 - 0.0098 16.6 3.6 0.022 15.4 3.6 1.6 1 0 0 1 1 1 1 Immortalisation up-regulated protein zf-C2H2_2 PF12756.7 EAU84003.2 - 0.027 14.8 1.9 0.093 13.1 1.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Caskin-tail PF16632.5 EAU84003.2 - 0.095 13.1 0.1 0.28 11.6 0.1 1.8 1 0 0 1 1 1 0 C-terminal region of Caskin 2-Hacid_dh_C PF02826.19 EAU84004.1 - 1.5e-54 184.1 0.0 2.2e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAU84004.1 - 2.6e-31 108.1 0.0 2.9e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAU84004.1 - 6.8e-05 23.1 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EAU84004.1 - 0.034 14.7 0.0 0.077 13.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EAU84004.1 - 0.043 13.4 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF374 PF04028.13 EAU84004.1 - 0.052 13.1 0.1 0.19 11.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF374) MCM PF00493.23 EAU84005.2 - 3.2e-99 330.6 0.0 4.6e-99 330.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAU84005.2 - 7.5e-37 126.0 0.5 1.4e-36 125.2 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAU84005.2 - 6.9e-29 100.1 2.6 1.5e-28 99.0 2.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAU84005.2 - 1.4e-16 61.0 0.1 4.9e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 EAU84005.2 - 2.5e-08 34.0 0.0 7.2e-08 32.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EAU84005.2 - 2e-07 30.6 0.0 5.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EAU84005.2 - 0.00021 21.1 0.0 0.0037 17.1 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAU84005.2 - 0.0012 18.6 0.1 0.96 9.1 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 EAU84005.2 - 0.0051 17.2 0.1 0.033 14.6 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain Con-6 PF10346.9 EAU84006.1 - 1.4e-34 117.8 0.7 4.1e-17 61.9 0.1 2.2 2 0 0 2 2 2 2 Conidiation protein 6 Abhydrolase_3 PF07859.13 EAU84007.2 - 6.6e-26 91.5 0.0 1e-20 74.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU84007.2 - 5.4e-10 38.7 0.0 9.1e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EAU84007.2 - 4.6e-07 29.3 0.0 1.8e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Con-6 PF10346.9 EAU84008.1 - 2.7e-29 100.9 3.6 2.8e-16 59.3 0.8 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 EAU84008.1 - 0.0094 15.8 1.2 1.2 8.9 0.0 2.2 1 1 1 2 2 2 2 SpoIIIAH-like protein GA-like PF17573.2 EAU84008.1 - 0.15 12.0 0.1 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 GA-like domain Glyco_hydro_16 PF00722.21 EAU84009.2 - 4.3e-06 26.3 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Con-6 PF10346.9 EAU84010.1 - 1.1e-06 28.5 0.3 0.00013 22.0 0.2 2.4 2 0 0 2 2 2 2 Conidiation protein 6 Con-6 PF10346.9 EAU84012.1 - 6.7e-32 109.2 4.3 2.2e-15 56.4 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 PASTA PF03793.19 EAU84012.1 - 0.00021 21.1 0.6 0.00059 19.6 0.1 1.8 2 0 0 2 2 2 1 PASTA domain YhzD PF14120.6 EAU84012.1 - 0.0078 16.3 0.7 1 9.5 0.1 2.2 2 0 0 2 2 2 2 YhzD-like protein SpoIIIAH PF12685.7 EAU84012.1 - 0.018 14.9 2.8 0.76 9.6 0.4 2.2 1 1 1 2 2 2 0 SpoIIIAH-like protein NuA4 PF09340.10 EAU84012.1 - 0.035 14.0 1.9 0.47 10.4 0.1 2.0 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 BTB PF00651.31 EAU84013.2 - 0.03 14.5 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain Coleoptericin PF06286.11 EAU84013.2 - 0.053 13.7 0.3 0.83 9.8 0.3 2.2 1 1 0 1 1 1 0 Coleoptericin p450 PF00067.22 EAU84014.2 - 6.3e-67 226.3 0.0 7.6e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU84016.2 - 3.3e-55 187.7 0.0 3.8e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU84017.2 - 1.7e-46 159.0 0.0 2.3e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.21 EAU84018.1 - 4e-47 160.4 0.0 6.1e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EAU84018.1 - 8.1e-06 25.6 11.2 0.0021 18.1 2.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU84018.1 - 0.00037 20.2 10.7 0.00039 20.1 1.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU84018.1 - 0.00099 19.1 1.1 0.00099 19.1 1.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU84018.1 - 0.0013 18.4 6.5 0.0016 18.0 0.2 3.3 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 EAU84018.1 - 0.0036 17.6 0.8 0.41 11.0 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU84018.1 - 0.0084 16.7 7.5 0.27 11.9 3.2 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF1796 PF08795.10 EAU84018.1 - 0.058 13.4 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) TPR_14 PF13428.6 EAU84018.1 - 0.18 12.7 5.0 0.57 11.1 2.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 EAU84018.1 - 0.49 10.6 2.4 2.9 8.1 2.2 2.1 2 0 0 2 2 2 0 HemY protein N-terminus TPR_6 PF13174.6 EAU84018.1 - 1.1 10.0 6.2 5.6 7.8 1.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat RhoGAP PF00620.27 EAU84019.2 - 9.5e-06 25.5 0.0 2.7e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain Motile_Sperm PF00635.26 EAU84019.2 - 0.018 14.9 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain PapD-like PF14874.6 EAU84019.2 - 0.035 14.3 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like PatG_D PF18047.1 EAU84019.2 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 PatG Domain INPP5B_PH PF16776.5 EAU84020.2 - 0.15 11.8 0.0 0.32 10.7 0.0 1.6 1 1 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain SET PF00856.28 EAU84021.1 - 3e-11 44.0 0.0 1.2e-09 38.8 0.0 2.6 2 1 0 2 2 2 1 SET domain Gemini_AC4_5 PF04807.12 EAU84021.1 - 0.16 11.7 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region HABP4_PAI-RBP1 PF04774.15 EAU84022.1 - 0.042 14.7 0.7 0.085 13.7 0.7 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family SET PF00856.28 EAU84025.1 - 2.1e-11 44.5 0.1 1.2e-10 42.1 0.0 2.2 2 1 0 2 2 2 1 SET domain PPR PF01535.20 EAU84025.1 - 1.4 9.4 3.6 0.4 11.1 0.1 2.0 2 0 0 2 2 2 0 PPR repeat Iso_dh PF00180.20 EAU84027.1 - 2.5e-75 253.8 0.0 3e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-CCHC_6 PF15288.6 EAU84029.2 - 0.01 15.6 1.5 0.026 14.3 1.5 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EAU84029.2 - 0.015 15.4 1.7 0.031 14.4 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EAU84029.2 - 0.16 11.7 2.2 0.33 10.7 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle PHD_3 PF13922.6 EAU84029.2 - 0.65 10.4 3.8 0.42 11.0 0.5 2.2 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Glyco_hydro_11 PF00457.17 EAU84034.1 - 5e-66 221.7 12.2 5.7e-66 221.5 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Dus PF01207.17 EAU84036.1 - 9.6e-54 182.6 0.0 1.6e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 EAU84036.1 - 1.2e-07 31.3 8.5 1.3e-05 24.9 0.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EAU84036.1 - 0.00013 21.8 5.1 0.15 12.0 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAU84036.1 - 0.00085 20.0 1.1 0.023 15.4 0.1 2.4 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 EAU84036.1 - 0.12 12.5 7.5 1.7 8.8 0.6 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 EAU84036.1 - 0.4 11.2 4.4 2.7 8.6 0.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger p450 PF00067.22 EAU84038.1 - 2.7e-71 240.7 0.0 2.5e-62 211.1 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 TPR_19 PF14559.6 EAU84041.1 - 8.8e-10 39.0 7.1 0.006 17.1 0.1 4.0 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAU84041.1 - 3.3e-06 27.4 2.5 0.00074 20.1 0.1 4.3 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU84041.1 - 5e-06 27.1 3.4 0.00092 19.8 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU84041.1 - 1.4e-05 24.8 2.5 0.0054 16.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU84041.1 - 1.4e-05 25.1 0.3 1.8 9.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU84041.1 - 0.00042 20.3 0.1 0.024 14.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAU84041.1 - 0.0016 18.5 1.7 0.016 15.3 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU84041.1 - 0.0037 17.0 0.1 0.031 14.1 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU84041.1 - 0.012 15.9 0.2 0.036 14.3 0.0 2.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TipAS PF07739.13 EAU84041.1 - 0.022 15.3 0.2 0.15 12.6 0.1 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain TPR_15 PF13429.6 EAU84041.1 - 0.029 13.6 1.9 0.038 13.2 0.6 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU84041.1 - 0.047 14.0 0.1 0.53 10.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU84041.1 - 0.051 13.3 2.7 2.4 7.9 0.1 3.5 2 1 1 3 3 3 0 TPR repeat DHHA2 PF02833.14 EAU84042.2 - 3.1e-27 95.5 2.0 6e-16 58.9 0.2 2.4 2 0 0 2 2 2 2 DHHA2 domain DHH PF01368.20 EAU84042.2 - 1.2e-10 41.5 0.0 3.9e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 DHH family SPX PF03105.19 EAU84043.2 - 0.19 11.6 5.0 0.2 11.5 5.0 1.3 1 0 0 1 1 1 0 SPX domain Mod_r PF07200.13 EAU84044.2 - 0.013 15.6 0.1 0.075 13.1 0.0 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TolA_bind_tri PF16331.5 EAU84044.2 - 0.023 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation SF-assemblin PF06705.11 EAU84044.2 - 0.034 13.5 0.0 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin SlyX PF04102.12 EAU84044.2 - 0.04 14.5 0.4 0.13 12.9 0.4 1.9 1 0 0 1 1 1 0 SlyX Macoilin PF09726.9 EAU84044.2 - 0.15 10.6 6.1 0.3 9.6 6.1 1.4 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 EAU84045.2 - 4.3e-07 30.5 4.1 0.08 13.8 0.0 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84045.2 - 4.5e-07 30.1 0.0 0.027 14.8 0.0 4.7 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Mlf1IP PF10248.9 EAU84046.2 - 0.11 12.5 0.7 0.27 11.2 0.7 1.7 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Aldedh PF00171.22 EAU84047.2 - 2.8e-129 431.6 0.0 3.3e-129 431.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3710 PF12502.8 EAU84047.2 - 0.0039 16.9 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3710) WD40 PF00400.32 EAU84048.2 - 3e-07 31.0 11.2 0.025 15.4 0.4 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40_like PF17005.5 EAU84048.2 - 0.027 13.8 0.0 1.2 8.4 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain BUD22 PF09073.10 EAU84048.2 - 0.12 11.7 18.3 0.19 11.0 18.3 1.2 1 0 0 1 1 1 0 BUD22 HGTP_anticodon2 PF12745.7 EAU84048.2 - 9.3 5.7 7.5 0.54 9.7 2.1 1.7 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Pkinase PF00069.25 EAU84049.1 - 1e-20 74.2 0.0 2.1e-20 73.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84049.1 - 7e-09 35.4 0.0 2.4e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAU84049.1 - 0.00051 19.4 0.2 0.00088 18.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAU84049.1 - 0.00053 18.9 0.1 0.00082 18.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU84049.1 - 0.0045 16.9 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU84049.1 - 0.097 12.0 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF4358 PF14270.6 EAU84049.1 - 0.15 12.3 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) NPR3 PF03666.13 EAU84050.2 - 2.3 6.9 4.2 2.9 6.6 4.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Thr_synth_N PF14821.6 EAU84052.2 - 4.7e-27 94.0 0.0 1.1e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EAU84052.2 - 6.9e-17 61.8 0.2 4.9e-16 59.0 0.2 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4440 PF14534.6 EAU84053.1 - 0.00031 21.1 0.0 0.00036 20.9 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EAU84053.1 - 0.0045 17.6 0.0 0.0071 17.0 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4829 PF16111.5 EAU84053.1 - 0.02 15.7 0.1 0.029 15.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4829) DUF5104 PF17117.5 EAU84053.1 - 0.025 15.0 0.0 0.037 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) DUF2683 PF10884.8 EAU84053.1 - 0.04 14.2 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) SnoaL_3 PF13474.6 EAU84053.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain Npa1 PF11707.8 EAU84054.2 - 0.009 15.4 0.4 0.013 14.9 0.4 1.2 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal DUF2935 PF11155.8 EAU84054.2 - 0.036 14.4 1.1 0.2 12.0 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2935) RNA_polI_A14 PF08203.11 EAU84054.2 - 0.093 13.5 0.2 0.23 12.2 0.2 1.7 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 ADIP PF11559.8 EAU84054.2 - 0.19 11.8 4.0 0.32 11.1 2.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Clusterin PF01093.17 EAU84054.2 - 0.31 10.0 2.8 0.65 9.0 2.7 1.5 1 1 0 1 1 1 0 Clusterin CLZ PF16526.5 EAU84054.2 - 2 8.9 4.3 7.8 6.9 0.1 3.4 3 2 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PP2C PF00481.21 EAU84055.2 - 1.6e-28 100.1 0.0 2.3e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EAU84055.2 - 2.2e-09 37.5 0.0 1.3e-05 25.2 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EAU84055.2 - 2e-06 27.6 0.0 2.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C STAG PF08514.11 EAU84056.2 - 1.2e-37 128.3 3.4 1.2e-37 128.3 0.3 2.8 2 1 0 2 2 2 1 STAG domain HEAT_2 PF13646.6 EAU84056.2 - 1.4e-09 38.2 0.1 3.7e-05 24.0 0.0 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 EAU84056.2 - 1.5e-06 28.0 0.4 0.39 11.1 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Trypan_PARP PF05887.11 EAU84056.2 - 0.0052 16.8 15.3 0.0052 16.8 15.3 3.5 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) Filament PF00038.21 EAU84056.2 - 0.17 11.5 3.1 0.15 11.6 1.2 1.8 2 0 0 2 2 2 0 Intermediate filament protein DUF2417 PF10329.9 EAU84059.2 - 0.037 13.5 0.8 0.065 12.6 0.8 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) CrgA PF06781.12 EAU84059.2 - 0.046 13.8 0.4 0.3 11.2 0.0 2.6 2 0 0 2 2 2 0 Cell division protein CrgA FxsA PF04186.13 EAU84059.2 - 0.099 12.8 5.9 0.63 10.2 0.1 2.9 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein OSTbeta PF15048.6 EAU84059.2 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Gram_pos_anchor PF00746.21 EAU84059.2 - 3.5 7.6 0.0 3.5 7.6 0.0 3.4 3 0 0 3 3 3 0 LPXTG cell wall anchor motif WD40 PF00400.32 EAU84060.2 - 9.1e-36 121.3 12.4 8.6e-07 29.6 0.1 8.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84060.2 - 2.2e-06 27.9 0.2 2.1 8.7 0.0 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAU84060.2 - 1.3e-05 24.7 0.0 0.00044 19.7 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 EAU84060.2 - 0.00025 19.8 10.8 0.077 11.6 0.0 4.8 3 1 2 5 5 5 2 Nucleoporin Nup120/160 F-box-like PF12937.7 EAU84060.2 - 0.00038 20.3 2.2 0.002 18.0 2.2 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84060.2 - 0.028 14.3 0.1 0.028 14.3 0.1 1.9 2 0 0 2 2 2 0 F-box domain DUF5046 PF16465.5 EAU84060.2 - 0.13 11.7 0.0 13 5.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5046) ApoLp-III PF07464.11 EAU84061.2 - 0.03 14.4 2.0 0.87 9.7 3.0 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Lebercilin PF15619.6 EAU84061.2 - 0.096 12.3 7.5 0.19 11.4 7.5 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Tektin PF03148.14 EAU84061.2 - 0.12 11.1 5.6 0.21 10.3 5.6 1.3 1 0 0 1 1 1 0 Tektin family UPF0242 PF06785.11 EAU84061.2 - 0.42 10.7 4.9 0.72 9.9 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4337 PF14235.6 EAU84061.2 - 0.72 10.0 2.9 1.4 9.0 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 EAU84061.2 - 1.6 8.0 3.2 3.3 7.0 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 EAU84062.2 - 7.8e-11 41.8 3.8 1.6e-10 40.8 3.8 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.18 EAU84063.2 - 7.5e-09 35.3 8.6 2.2e-08 33.7 8.6 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein LTXXQ PF07813.12 EAU84063.2 - 1.7 9.4 7.9 2.6 8.8 0.4 3.1 2 1 1 3 3 3 0 LTXXQ motif family protein ArsB PF02040.15 EAU84064.1 - 1e-08 35.0 10.7 1e-08 35.0 10.7 2.7 2 1 0 2 2 2 2 Arsenical pump membrane protein tRNA-synt_2b PF00587.25 EAU84065.1 - 7.5e-38 130.3 1.2 2.5e-37 128.6 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EAU84065.1 - 7.4e-20 71.2 8.3 7.4e-20 71.2 8.3 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 EAU84065.1 - 0.028 14.5 2.3 0.065 13.3 2.3 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 EAU84065.1 - 0.23 10.7 4.7 0.38 10.0 4.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein CCDC-167 PF15188.6 EAU84065.1 - 0.43 11.0 4.3 0.35 11.3 1.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Gly_transf_sug PF04488.15 EAU84066.2 - 2.7e-05 24.7 0.0 6.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EAU84066.2 - 0.05 13.0 0.2 0.08 12.3 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribonuc_2-5A PF06479.12 EAU84069.1 - 5.4e-46 155.9 0.1 9.4e-46 155.1 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EAU84069.1 - 2.7e-38 131.9 0.0 6.3e-30 104.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84069.1 - 2.2e-19 69.7 0.0 2.3e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU84069.1 - 9e-05 21.4 0.0 0.00018 20.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 EAU84069.1 - 0.00016 21.4 0.0 0.0047 16.8 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 EAU84069.1 - 0.0027 17.3 0.0 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.14 EAU84069.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MoCF_biosynth PF00994.24 EAU84070.1 - 4.9e-35 120.3 0.0 9.9e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain UPF0139 PF03669.13 EAU84071.1 - 0.0032 17.3 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Inhibitor_I9 PF05922.16 EAU84072.1 - 2.5e-06 28.1 0.0 4.6e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 BetaGal_dom2 PF10435.9 EAU84072.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 DUF1129 PF06570.11 EAU84073.2 - 0.0028 17.2 1.2 0.0032 17.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Peptidase_S24 PF00717.23 EAU84074.1 - 0.00026 20.9 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like GPI-anchored PF10342.9 EAU84075.2 - 1.5e-08 35.3 0.1 2.8e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zn_clus PF00172.18 EAU84076.1 - 7.2e-05 22.8 9.7 0.00012 22.1 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAU84076.1 - 0.02 13.9 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain GTP1_OBG PF01018.22 EAU84077.1 - 2.7e-42 144.0 0.6 1.7e-29 102.4 0.1 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EAU84077.1 - 6e-20 71.4 0.0 1.3e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU84077.1 - 1.1e-06 28.3 0.0 4.4e-06 26.3 0.0 2.0 3 0 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.21 EAU84077.1 - 0.00034 20.1 0.3 0.46 9.9 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.19 EAU84077.1 - 0.00064 19.4 0.1 0.22 11.1 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EAU84077.1 - 0.00094 18.8 0.8 0.1 12.1 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EAU84077.1 - 0.002 17.1 1.5 0.82 8.6 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EAU84077.1 - 0.012 15.7 0.0 0.033 14.2 0.0 1.8 1 1 0 1 1 1 0 Dynamin family ABC_tran PF00005.27 EAU84077.1 - 0.015 15.8 0.1 0.034 14.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 EAU84077.1 - 0.025 14.5 0.6 0.047 13.6 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Gtr1_RagA PF04670.12 EAU84077.1 - 0.033 13.6 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 EAU84077.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain HLH PF00010.26 EAU84078.2 - 1.8e-12 47.0 0.3 4.7e-12 45.7 0.3 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 EAU84079.2 - 3.1e-08 34.2 16.4 0.047 14.6 1.3 7.0 7 1 0 7 7 7 3 WD domain, G-beta repeat HAND PF09110.11 EAU84079.2 - 5 7.9 14.5 0.072 13.9 6.7 1.9 2 0 0 2 2 2 0 HAND Con-6 PF10346.9 EAU84080.1 - 2.3e-47 158.7 10.2 1.3e-15 57.1 0.2 3.1 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 EAU84080.1 - 0.00024 21.0 5.0 0.048 13.5 0.1 3.0 2 1 0 3 3 3 2 SpoIIIAH-like protein DEC-1_C PF04626.13 EAU84080.1 - 0.0014 19.0 0.8 0.013 15.9 0.4 2.3 1 1 1 2 2 2 1 Dec-1 protein, C terminal region Host_attach PF10116.9 EAU84080.1 - 0.095 13.3 1.3 0.16 12.6 0.3 1.8 1 1 1 2 2 2 0 Protein required for attachment to host cells UBA PF00627.31 EAU84080.1 - 0.14 12.1 0.2 0.96 9.4 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain ATP-synt_DE PF00401.20 EAU84080.1 - 0.16 12.3 4.0 20 5.5 0.0 3.2 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain LapD_MoxY_N PF16448.5 EAU84081.2 - 0.015 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain AAA_12 PF13087.6 EAU84082.2 - 7.8e-32 110.5 0.1 2.3e-31 109.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU84082.2 - 2.3e-20 73.1 0.0 2.1e-19 70.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EAU84082.2 - 1.9e-17 63.9 0.4 6.1e-09 36.0 0.0 2.9 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EAU84082.2 - 4.7e-12 46.5 0.0 3.7e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EAU84082.2 - 2.8e-05 24.0 0.1 0.57 9.9 0.0 3.4 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EAU84082.2 - 6e-05 23.5 0.0 0.00016 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU84082.2 - 0.00011 22.5 1.5 0.01 16.1 0.0 4.0 6 0 0 6 6 4 1 AAA domain AAA PF00004.29 EAU84082.2 - 0.0012 19.3 0.0 0.0037 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EAU84082.2 - 0.0017 17.7 0.0 0.93 8.7 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EAU84082.2 - 0.0021 17.2 0.0 0.0044 16.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.14 EAU84082.2 - 0.0027 16.9 0.0 0.006 15.8 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase Helicase_RecD PF05127.14 EAU84082.2 - 0.0036 17.2 0.9 0.074 12.9 0.0 3.2 3 1 0 3 3 3 1 Helicase AAA_28 PF13521.6 EAU84082.2 - 0.0064 16.8 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain Y_phosphatase PF00102.27 EAU84082.2 - 0.013 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ResIII PF04851.15 EAU84082.2 - 0.016 15.2 0.0 0.051 13.6 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EAU84082.2 - 0.02 15.5 0.0 0.079 13.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EAU84082.2 - 0.026 14.1 0.3 0.21 11.1 0.0 2.4 3 0 0 3 3 2 0 P-loop containing dynein motor region SRP54 PF00448.22 EAU84082.2 - 0.033 13.8 0.0 0.33 10.6 0.0 2.5 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EAU84082.2 - 0.054 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EAU84082.2 - 0.07 13.0 0.3 0.82 9.6 0.0 2.7 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 EAU84082.2 - 0.07 13.3 0.1 0.51 10.5 0.0 2.6 3 0 0 3 3 1 0 AAA domain NB-ARC PF00931.22 EAU84082.2 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Hydin_ADK PF17213.3 EAU84082.2 - 0.13 12.5 0.1 0.13 12.5 0.1 2.2 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain DEAD PF00270.29 EAU84082.2 - 0.13 12.0 0.1 0.61 9.8 0.1 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 EAU84082.2 - 0.16 11.4 0.0 0.35 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 EAU84082.2 - 0.19 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain CBM_1 PF00734.18 EAU84083.1 - 4.5e-11 42.5 15.9 4.5e-11 42.5 15.9 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_2 PF02230.16 EAU84083.1 - 0.00023 21.0 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EAU84083.1 - 0.0014 18.1 0.2 0.0027 17.2 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EAU84083.1 - 0.0021 17.6 0.0 0.0041 16.6 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 EAU84083.1 - 0.0031 17.2 0.4 0.021 14.5 0.5 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EAU84083.1 - 0.0079 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2156 PF09924.9 EAU84084.1 - 2.5e-13 49.7 0.0 1.6e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2156) BORG_CEP PF14957.6 EAU84084.1 - 0.013 16.7 1.6 0.028 15.6 1.6 1.6 1 0 0 1 1 1 0 Cdc42 effector Cu_amine_oxid PF01179.20 EAU84085.1 - 3.3e-128 428.1 7.6 5e-128 427.5 7.6 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EAU84085.1 - 2.8e-27 94.3 0.1 6e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EAU84085.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain GPI-anchored PF10342.9 EAU84087.1 - 2.5e-06 28.2 0.4 6.2e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UCH PF00443.29 EAU84089.2 - 2e-07 30.8 0.0 3.5e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MerR-DNA-bind PF09278.11 EAU84089.2 - 0.41 11.2 0.1 0.41 11.2 0.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding F-box-like PF12937.7 EAU84090.2 - 6.8e-06 25.9 0.8 3.3e-05 23.7 0.1 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EAU84090.2 - 2e-05 24.3 1.3 0.0068 16.3 0.0 3.6 4 0 0 4 4 4 2 F-box domain DUF775 PF05603.12 EAU84093.2 - 4.6e-26 91.6 0.0 5e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) F-box PF00646.33 EAU84094.1 - 2.1e-09 37.0 1.2 4.4e-09 36.0 1.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU84094.1 - 9.3e-08 31.8 0.8 1.9e-07 30.8 0.8 1.5 1 0 0 1 1 1 1 F-box-like Thaumatin PF00314.17 EAU84097.1 - 2.5e-73 246.3 3.9 2.8e-73 246.1 3.9 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EAU84097.1 - 0.033 13.5 0.0 0.16 11.2 0.0 1.8 1 1 0 1 1 1 0 Beta-1,3-glucanase Thaumatin PF00314.17 EAU84098.2 - 1.3e-72 243.9 5.8 1.5e-72 243.7 5.8 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EAU84098.2 - 0.13 11.5 0.6 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 Beta-1,3-glucanase Glucan_synthase PF02364.15 EAU84099.2 - 0 1312.2 0.0 0 1311.7 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EAU84099.2 - 7.9e-43 145.9 0.1 2.2e-42 144.4 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Velvet PF11754.8 EAU84100.2 - 3e-39 135.5 0.4 1.1e-38 133.6 0.0 1.9 2 0 0 2 2 2 1 Velvet factor Sod_Fe_C PF02777.18 EAU84101.2 - 7.1e-37 125.7 0.8 1.2e-36 125.0 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EAU84101.2 - 3.9e-31 107.4 2.7 3.9e-31 107.4 2.7 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ocnus PF05005.15 EAU84101.2 - 0.032 14.4 0.1 0.42 10.8 0.1 2.1 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) Cytochrome_P460 PF16694.5 EAU84101.2 - 0.25 11.7 1.5 0.8 10.1 1.5 1.8 1 1 0 1 1 1 0 Cytochrome P460 Plus-3 PF03126.18 EAU84104.2 - 4.2e-35 120.6 0.1 1.7e-34 118.6 0.1 2.1 2 0 0 2 2 2 1 Plus-3 domain WD40 PF00400.32 EAU84105.2 - 2.2e-39 132.7 15.0 1e-09 38.8 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84105.2 - 1.3e-12 47.8 1.2 0.016 15.5 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU84105.2 - 1.1e-08 34.5 0.4 0.14 11.1 0.0 4.6 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAU84105.2 - 5.8e-07 28.5 2.1 0.095 11.3 0.0 3.9 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Hira PF07569.11 EAU84105.2 - 4.1e-06 26.7 0.1 0.019 14.7 0.0 2.7 1 1 2 3 3 3 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EAU84105.2 - 5.9e-05 22.0 0.4 0.0013 17.6 0.1 2.9 1 1 1 2 2 2 1 Nup133 N terminal like PALB2_WD40 PF16756.5 EAU84105.2 - 0.00019 20.4 1.9 0.00041 19.4 0.1 2.3 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EAU84105.2 - 0.018 13.4 0.0 0.032 12.6 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF3642 PF12182.8 EAU84105.2 - 0.089 13.1 0.0 7.8 6.9 0.0 2.9 1 1 1 3 3 3 0 Bacterial lipoprotein Peptidase_M20 PF01546.28 EAU84106.1 - 1.4e-33 116.4 0.0 1.8e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAU84106.1 - 6.6e-14 51.8 0.0 1.1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain FMN_red PF03358.15 EAU84106.1 - 0.041 13.6 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Peptidase_M28 PF04389.17 EAU84106.1 - 0.074 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 SUZ PF12752.7 EAU84107.1 - 4.8e-15 56.1 3.2 4.8e-15 56.1 3.2 3.7 4 1 0 4 4 4 1 SUZ domain eIF3_subunit PF08597.10 EAU84107.1 - 0.31 10.9 17.3 0.91 9.4 17.3 1.7 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit MCLC PF05934.11 EAU84107.1 - 1.3 7.7 3.0 1.7 7.3 3.0 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) BLOC1S3 PF15753.5 EAU84107.1 - 4.7 7.3 6.8 3.1 7.9 4.6 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 UDPG_MGDP_dh_N PF03721.14 EAU84108.2 - 3.3e-59 199.6 0.0 6.7e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EAU84108.2 - 4.5e-35 120.3 0.1 4e-34 117.2 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EAU84108.2 - 1.4e-31 108.5 0.1 5.3e-31 106.7 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 EAU84108.2 - 0.098 12.9 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EAU84108.2 - 0.12 13.0 0.2 7.6 7.2 0.1 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Thaumatin PF00314.17 EAU84109.1 - 1.4e-73 247.1 9.2 1.6e-73 246.9 9.2 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EAU84109.1 - 0.063 12.6 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Beta-1,3-glucanase Pyr_redox_2 PF07992.14 EAU84110.2 - 7.7e-42 143.5 0.0 1e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU84110.2 - 1.5e-10 41.5 0.0 5.3e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU84110.2 - 0.0073 15.6 0.0 2.7 7.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Carbam_trans_C PF16861.5 EAU84110.2 - 0.11 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus WH1 PF00568.23 EAU84111.1 - 3.4e-10 39.9 0.1 2.8e-09 36.9 0.1 2.2 1 1 0 1 1 1 1 WH1 domain PBD PF00786.28 EAU84111.1 - 0.075 13.4 0.8 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 P21-Rho-binding domain SAP PF02037.27 EAU84113.1 - 1e-05 25.2 0.7 2.6e-05 23.8 0.7 1.7 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.13 EAU84113.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 LETM1-like protein DUF4855 PF16147.5 EAU84114.2 - 0.016 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) Aminotran_1_2 PF00155.21 EAU84115.2 - 2.2e-53 181.7 0.0 2.9e-51 174.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EAU84115.2 - 0.0053 16.1 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 EAU84115.2 - 0.0098 14.7 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 EAU84115.2 - 0.022 13.7 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Tmemb_18A PF09771.9 EAU84115.2 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 DAO PF01266.24 EAU84116.2 - 1.2e-61 209.2 1.6 1.2e-61 209.2 1.6 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU84116.2 - 2.8e-07 30.1 0.0 0.0027 17.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU84116.2 - 4.1e-05 23.7 0.0 0.00015 21.9 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 EAU84116.2 - 8.2e-05 22.1 0.0 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.27 EAU84116.2 - 0.00083 19.9 0.1 0.0031 18.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU84116.2 - 0.002 17.3 0.2 0.042 12.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EAU84116.2 - 0.007 16.4 0.6 0.071 13.1 0.2 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EAU84116.2 - 0.0076 15.2 0.1 0.12 11.1 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 EAU84116.2 - 0.36 9.9 1.2 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pkinase PF00069.25 EAU84121.2 - 6.2e-68 229.0 0.0 1.1e-38 133.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84121.2 - 1.7e-25 89.8 0.2 1e-13 51.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase VIT1 PF01988.19 EAU84122.1 - 4.2e-64 216.4 5.0 5e-64 216.1 5.0 1.1 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.11 EAU84122.1 - 0.071 13.0 5.0 0.12 12.3 5.0 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF4389 PF14333.6 EAU84122.1 - 0.084 12.8 0.8 4.6 7.2 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Adeno_E3 PF06040.11 EAU84122.1 - 0.18 12.0 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 protein Aminotran_1_2 PF00155.21 EAU84123.1 - 9.4e-39 133.6 0.0 1.3e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Gmx_para_CXXCG PF09535.10 EAU84123.1 - 0.16 11.3 0.0 6.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Copper-fist PF00649.18 EAU84124.2 - 7.1e-21 73.4 1.7 7.1e-21 73.4 1.7 2.5 3 0 0 3 3 3 1 Copper fist DNA binding domain DUF4199 PF13858.6 EAU84124.2 - 0.32 11.4 0.3 0.47 10.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) WD40 PF00400.32 EAU84125.2 - 1e-22 79.9 5.8 0.00029 21.6 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84125.2 - 0.001 19.3 0.1 0.1 12.9 0.1 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4813 PF16072.5 EAU84125.2 - 0.031 14.0 0.2 0.052 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) YiaAB PF05360.14 EAU84125.2 - 0.2 12.0 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 yiaA/B two helix domain Peptidase_C14 PF00656.22 EAU84126.2 - 4.6e-21 75.9 0.0 7.4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain GATA-N PF05349.12 EAU84126.2 - 0.035 14.4 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal Zn_ribbon_17 PF17120.5 EAU84127.2 - 7.4e-07 28.7 2.1 7.4e-07 28.7 2.1 2.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EAU84127.2 - 0.00088 20.0 12.3 0.33 11.9 1.4 5.3 5 1 0 5 5 5 2 WD domain, G-beta repeat Zf_RING PF16744.5 EAU84127.2 - 0.011 15.9 3.7 0.024 14.7 3.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 EAU84127.2 - 0.054 13.4 3.6 0.21 11.5 3.6 2.0 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 EAU84127.2 - 0.8 10.1 8.2 1.8 8.9 8.2 1.6 1 0 0 1 1 1 0 C1 domain CDC45 PF02724.14 EAU84127.2 - 1.7 6.9 11.1 2.6 6.2 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein C1_1 PF00130.22 EAU84127.2 - 5.1 7.1 9.7 21 5.1 9.7 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CCDC106 PF15794.5 EAU84127.2 - 8.8 6.0 8.3 31 4.2 8.3 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CRC_subunit PF08624.10 EAU84128.2 - 1.8e-43 148.2 0.0 3.1e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit HAT PF02184.16 EAU84129.2 - 4.7e-19 68.0 49.8 1e-09 38.2 2.0 11.0 12 1 0 12 12 11 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EAU84129.2 - 1.4e-16 59.7 13.5 0.0041 17.8 0.0 8.7 3 2 6 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAU84129.2 - 2.3e-11 42.9 0.7 0.68 10.2 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat Suf PF05843.14 EAU84129.2 - 2.4e-10 40.9 8.0 7.6e-06 26.1 0.4 3.7 2 1 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EAU84129.2 - 1.2e-07 32.2 0.0 0.017 15.7 0.0 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU84129.2 - 1.6e-07 31.9 6.7 0.017 15.8 0.0 5.3 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU84129.2 - 1.5e-05 24.5 0.1 0.4 10.4 0.0 4.7 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.6 EAU84129.2 - 8.2e-05 22.5 2.1 9 6.8 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAU84129.2 - 0.00011 22.2 5.2 1.1 9.4 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU84129.2 - 0.00035 20.3 0.0 11 6.0 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EAU84129.2 - 0.0004 20.4 7.1 0.12 12.4 0.3 5.0 4 2 1 5 5 5 1 U3 small nucleolar RNA-associated protein 6 Mad3_BUB1_I PF08311.12 EAU84129.2 - 0.0013 18.7 20.3 0.3 11.1 0.7 6.7 2 2 2 5 5 5 2 Mad3/BUB1 homology region 1 SNAP PF14938.6 EAU84129.2 - 0.0016 17.9 0.4 0.026 14.0 0.2 2.5 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EAU84129.2 - 0.0017 18.6 1.7 0.74 10.1 0.1 4.2 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU84129.2 - 0.24 11.5 7.6 13 6.1 0.0 5.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAU84129.2 - 0.27 12.0 3.6 62 4.6 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EAU84129.2 - 0.6 10.4 2.8 1.9 8.7 0.1 2.8 3 0 0 3 3 3 0 c-SKI Smad4 binding domain TAF4 PF05236.14 EAU84130.2 - 0.062 13.0 10.1 0.077 12.7 10.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Radial_spoke_3 PF06098.11 EAU84130.2 - 0.41 9.9 2.9 0.31 10.3 1.4 1.5 1 1 0 1 1 1 0 Radial spoke protein 3 PI3K_1B_p101 PF10486.9 EAU84130.2 - 0.83 7.4 4.3 1 7.0 4.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Miga PF10265.9 EAU84130.2 - 3.9 6.3 6.6 5 6.0 6.6 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 EAU84130.2 - 8.6 4.8 9.0 9.8 4.6 9.0 1.1 1 0 0 1 1 1 0 Macoilin family zf-rbx1 PF12678.7 EAU84133.2 - 3.1e-24 85.0 12.9 4.1e-24 84.6 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAU84133.2 - 1.7e-16 60.0 9.6 2.4e-16 59.6 9.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EAU84133.2 - 8.8e-06 26.0 15.5 0.00032 21.0 15.5 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU84133.2 - 4.6e-05 23.2 3.6 4.6e-05 23.2 3.6 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU84133.2 - 0.0013 18.5 11.8 0.025 14.5 11.8 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAU84133.2 - 0.042 13.5 2.6 0.042 13.5 2.6 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EAU84133.2 - 0.22 11.6 6.8 0.72 9.9 6.8 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAU84133.2 - 0.23 11.4 10.7 0.67 9.9 4.5 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EAU84133.2 - 0.27 11.4 9.4 1 9.6 9.5 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EAU84133.2 - 1.6 8.5 16.9 84 3.0 16.9 2.4 1 1 0 1 1 1 0 RING-like zinc finger TBCC PF07986.12 EAU84134.1 - 6.8e-20 71.0 1.3 3.3e-19 68.8 1.2 2.0 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EAU84134.1 - 8.5e-11 42.3 1.9 1.4e-10 41.6 1.9 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain ABC_tran_CTD PF16326.5 EAU84134.1 - 0.0071 16.6 1.0 0.15 12.4 0.1 2.2 2 0 0 2 2 2 1 ABC transporter C-terminal domain Cob_adeno_trans PF01923.18 EAU84134.1 - 0.01 16.0 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase CLZ PF16526.5 EAU84134.1 - 1.7 9.0 4.4 30 5.1 0.2 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSP20 PF00011.21 EAU84136.1 - 2.4e-14 53.3 0.0 3.6e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAU84136.1 - 9.3e-07 28.3 0.0 2.7e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CSTF_C PF14304.6 EAU84137.1 - 3.9e-14 51.9 3.1 9.2e-14 50.7 3.1 1.7 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 EAU84137.1 - 1.8e-12 47.6 0.5 4.6e-12 46.2 0.5 1.8 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 UQ_con PF00179.26 EAU84139.1 - 6.7e-12 45.2 0.0 2e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DUF5320 PF17253.2 EAU84139.1 - 0.015 16.4 0.1 0.034 15.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) FoP_duplication PF13865.6 EAU84139.1 - 8.8 7.0 8.2 21 5.8 8.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 VPS9 PF02204.18 EAU84140.2 - 1.3e-17 63.9 0.0 1.1e-14 54.5 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain FAM176 PF14851.6 EAU84140.2 - 3.6 7.2 15.8 0.85 9.3 6.3 2.4 2 0 0 2 2 2 0 FAM176 family DUF4764 PF15961.5 EAU84141.1 - 0.043 12.5 2.3 0.061 12.0 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) SDA1 PF05285.12 EAU84141.1 - 4.4 6.6 16.4 6.7 6.0 16.4 1.3 1 0 0 1 1 1 0 SDA1 SlyX PF04102.12 EAU84144.2 - 0.039 14.6 4.5 0.066 13.8 2.9 2.3 1 1 0 1 1 1 0 SlyX KASH_CCD PF14662.6 EAU84144.2 - 0.1 12.4 4.9 0.17 11.7 4.9 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH BRE1 PF08647.11 EAU84144.2 - 0.2 11.7 7.7 0.046 13.8 3.3 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 EAU84144.2 - 0.31 11.1 2.4 0.45 10.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EAU84144.2 - 0.36 10.6 3.9 0.77 9.6 3.9 1.5 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 EAU84144.2 - 0.8 10.2 6.6 1.9 9.0 6.6 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 EAU84144.2 - 1.4 9.0 7.7 2.1 8.4 7.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PHP PF02811.19 EAU84145.2 - 2.1e-14 54.1 0.0 3.2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 PHP domain DUF1308 PF07000.11 EAU84147.2 - 0.003 17.5 0.0 2.5 8.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1308) Mito_carr PF00153.27 EAU84148.2 - 1.6e-63 210.6 0.9 3.7e-23 81.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 EAU84149.1 - 1.5e-26 93.3 0.0 2.3e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84149.1 - 1.8e-15 56.9 0.0 2.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAU84149.1 - 4.3e-05 23.0 0.0 7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU84149.1 - 0.00068 19.6 0.1 0.0014 18.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EAU84149.1 - 0.036 13.7 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Cas9-BH PF16593.5 EAU84149.1 - 0.15 11.8 0.1 0.37 10.5 0.1 1.7 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Pkinase_fungal PF17667.1 EAU84149.1 - 6.6 5.4 7.5 37 2.9 7.5 2.0 1 1 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EAU84150.2 - 9.8e-16 57.9 0.0 6.6e-15 55.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EAU84150.2 - 6.7e-14 52.1 15.4 1.3e-07 32.1 0.2 6.3 6 0 0 6 6 5 2 WD domain, G-beta repeat HEAT PF02985.22 EAU84150.2 - 1.4e-11 43.6 5.5 0.0023 18.0 0.1 5.2 4 0 0 4 4 4 3 HEAT repeat Pkinase_Tyr PF07714.17 EAU84150.2 - 5.4e-07 29.1 0.0 9.6e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EAU84150.2 - 1.4e-05 25.3 0.5 0.077 13.4 0.1 3.5 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EAU84150.2 - 0.00086 19.8 0.3 0.21 12.1 0.1 3.0 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 EAU84150.2 - 0.0018 18.3 2.1 1.3 9.0 0.9 3.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 EAU84150.2 - 0.0064 16.8 0.3 2.2 8.6 0.0 3.2 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cohesin_HEAT PF12765.7 EAU84150.2 - 0.015 15.6 2.5 10 6.6 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 EAU84150.2 - 0.041 14.5 0.3 17 6.1 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Ge1_WD40 PF16529.5 EAU84150.2 - 0.047 12.6 0.1 0.085 11.8 0.1 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EAU84150.2 - 0.055 12.2 0.4 8.2 5.0 0.0 3.2 3 1 1 4 4 4 0 Nup133 N terminal like Tti2 PF10521.9 EAU84150.2 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Tti2 family Adaptin_N PF01602.20 EAU84150.2 - 0.15 10.6 2.7 0.45 9.0 0.6 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HAND PF09110.11 EAU84151.2 - 0.021 15.6 0.1 0.044 14.5 0.1 1.5 1 0 0 1 1 1 0 HAND Peptidase_S41 PF03572.18 EAU84152.2 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Abhydrolase_6 PF12697.7 EAU84154.1 - 3.9e-12 47.2 0.1 7.5e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU84154.1 - 9.2e-07 28.8 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU84154.1 - 0.00027 20.5 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EAU84154.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAU84154.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EAU84154.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_8 PF06259.12 EAU84154.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase PAF-AH_p_II PF03403.13 EAU84154.1 - 0.19 10.2 0.0 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II P66_CC PF16563.5 EAU84154.1 - 0.56 9.9 3.0 0.95 9.1 3.0 1.3 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 NYN PF01936.18 EAU84160.2 - 2.2e-05 25.0 0.0 3.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NYN domain DUF5584 PF17822.1 EAU84160.2 - 0.0004 19.9 0.0 0.00054 19.5 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5584) NYN PF01936.18 EAU84161.2 - 1.5e-09 38.4 0.0 3.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 NYN domain Abhydrolase_2 PF02230.16 EAU84164.1 - 4.2e-06 26.7 0.2 0.005 16.7 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EAU84164.1 - 0.093 13.3 2.9 0.71 10.4 2.9 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family IFT20 PF14931.6 EAU84168.1 - 0.034 14.3 0.7 0.046 13.9 0.7 1.4 1 1 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 ATPgrasp_N PF18130.1 EAU84168.1 - 0.067 13.8 0.1 0.19 12.3 0.0 1.9 1 1 1 2 2 2 0 ATP-grasp N-terminal domain ARGLU PF15346.6 EAU84168.1 - 0.086 12.7 3.3 0.2 11.6 3.3 1.6 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Baculo_gp41 PF04700.12 EAU84168.1 - 0.12 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region DnaT PF17948.1 EAU84171.1 - 0.21 11.3 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 DnaT DNA-binding domain Ecl1 PF12855.7 EAU84173.1 - 0.88 10.7 23.8 0.13 13.5 10.9 2.3 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins KDZ PF18758.1 EAU84174.2 - 5.3e-60 202.8 0.0 8.3e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EAU84174.2 - 9.3e-09 35.4 0.1 2.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU84174.2 - 0.00097 19.3 0.1 0.0018 18.4 0.1 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Fib_alpha PF08702.10 EAU84181.2 - 0.0022 18.2 1.7 0.0058 16.8 1.7 1.8 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family PV-1 PF06637.11 EAU84181.2 - 0.4 9.4 3.2 4.5 6.0 0.4 2.2 1 1 1 2 2 2 0 PV-1 protein (PLVAP) Spc7 PF08317.11 EAU84181.2 - 1.1 8.1 9.4 0.25 10.2 4.9 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein DHR10 PF18595.1 EAU84181.2 - 1.3 9.1 7.1 0.43 10.6 1.8 2.8 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Nop14 PF04147.12 EAU84182.2 - 0.014 13.7 9.7 0.02 13.1 9.7 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EAU84182.2 - 0.84 8.1 5.2 1.3 7.5 5.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Roughex PF06020.11 EAU84182.2 - 1.9 7.5 10.0 4.5 6.3 10.0 1.5 1 0 0 1 1 1 0 Drosophila roughex protein KDZ PF18758.1 EAU84183.2 - 8.6e-46 156.3 0.2 8.6e-46 156.3 0.2 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU84183.2 - 2.5e-21 75.9 0.0 5.9e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU84183.2 - 0.0011 19.1 0.0 0.0028 17.8 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases LPD22 PF18834.1 EAU84183.2 - 0.014 15.5 0.2 0.05 13.8 0.0 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 Tet_JBP PF12851.7 EAU84185.2 - 7.5e-07 28.8 0.0 9.9e-06 25.1 0.0 2.0 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Helitron_like_N PF14214.6 EAU84190.2 - 7.5e-28 98.0 0.0 1.9e-27 96.7 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAU84190.2 - 1.1e-24 87.4 0.1 2.7e-22 79.4 0.1 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAU84190.2 - 1.2e-10 41.5 0.0 2.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU84190.2 - 2.1e-05 24.9 0.0 4.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EAU84190.2 - 0.016 14.4 0.1 0.042 13.0 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain Nop14 PF04147.12 EAU84192.2 - 5e-297 987.8 15.7 5.9e-297 987.6 15.7 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 EAU84192.2 - 0.18 11.1 0.0 0.42 9.8 0.0 1.6 1 0 0 1 1 1 0 Noc2p family T6PP_N PF18572.1 EAU84192.2 - 0.25 11.2 2.9 5 7.0 0.1 3.0 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain PAP_central PF04928.17 EAU84193.2 - 3e-110 367.1 0.0 4.1e-110 366.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EAU84193.2 - 1.4e-57 194.1 0.0 2.3e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EAU84193.2 - 2.2e-11 43.9 0.0 5.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EAU84193.2 - 0.019 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 EAU84193.2 - 0.18 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF4487 PF14868.6 EAU84194.2 - 0.0038 16.1 0.9 0.6 8.9 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4487) Mgm101p PF06420.12 EAU84195.1 - 6.6e-88 292.6 0.0 9.1e-88 292.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PI3_PI4_kinase PF00454.27 EAU84196.2 - 2.5e-56 191.3 0.0 5.1e-56 190.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EAU84196.2 - 2.8e-26 92.6 0.5 1.1e-25 90.6 0.0 2.2 2 1 0 2 2 2 1 FAT domain UME PF08064.13 EAU84196.2 - 1.3e-24 86.0 0.1 4.5e-24 84.3 0.1 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 EAU84196.2 - 3.1e-10 39.7 0.0 8.8e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 EAU84196.2 - 4.8e-05 23.3 0.2 0.00094 19.1 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EAU84196.2 - 0.17 12.5 0.1 68 4.1 0.0 3.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region YEATS PF03366.16 EAU84197.1 - 2e-37 127.0 0.0 3e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 YEATS family PEP-utilisers_N PF05524.13 EAU84197.1 - 0.2 11.8 1.5 0.31 11.2 0.7 1.7 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Bap31_Bap29_C PF18035.1 EAU84197.1 - 0.5 10.4 4.5 0.99 9.5 4.5 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain COX7a PF02238.15 EAU84198.1 - 1.1e-19 70.5 0.1 1.5e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Thioredoxin_4 PF13462.6 EAU84200.1 - 2.4e-12 47.3 0.0 4.7e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EAU84200.1 - 0.023 14.5 0.0 0.18 11.6 0.0 2.2 2 1 0 2 2 2 0 DSBA-like thioredoxin domain PCI PF01399.27 EAU84202.2 - 5.1e-13 49.4 0.0 1.1e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain Cyclin_N PF00134.23 EAU84203.1 - 1.2e-05 25.0 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain IU_nuc_hydro PF01156.19 EAU84204.2 - 2.3e-81 273.7 0.0 2.6e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_S28 PF05577.12 EAU84205.2 - 1.5e-43 149.2 0.0 3.1e-31 108.6 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EAU84205.2 - 0.064 11.9 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 WD40 PF00400.32 EAU84207.2 - 3.3e-05 24.6 4.4 0.44 11.5 1.2 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat PD40 PF07676.12 EAU84207.2 - 0.11 12.4 0.0 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Sulfate_transp PF00916.20 EAU84208.2 - 1.3e-81 274.3 18.8 2.1e-81 273.6 18.8 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EAU84208.2 - 2.4e-18 65.9 0.0 4.7e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EAU84208.2 - 0.11 12.9 0.0 0.45 10.9 0.0 2.2 1 1 0 1 1 1 0 STAS domain TFIID-18kDa PF02269.16 EAU84209.1 - 2e-32 111.1 0.1 3.7e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 EAU84209.1 - 0.00033 20.9 2.4 0.002 18.4 0.9 2.3 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha Asp_protease PF09668.10 EAU84210.1 - 2.7e-58 195.1 0.1 4.8e-58 194.3 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EAU84210.1 - 1.2e-21 77.1 0.0 3.4e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EAU84210.1 - 3.4e-10 40.4 0.0 9.5e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 EAU84210.1 - 8.7e-09 35.0 0.0 1.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 EAU84210.1 - 0.0012 18.6 0.8 0.0027 17.4 0.8 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 EAU84210.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EAU84210.1 - 0.0018 18.2 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EAU84210.1 - 0.0029 17.4 0.2 0.013 15.3 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain RVP PF00077.20 EAU84210.1 - 0.0031 17.8 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_M8 PF01457.16 EAU84210.1 - 0.025 13.3 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 Leishmanolysin RVP_2 PF08284.11 EAU84210.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease HMG_box PF00505.19 EAU84211.1 - 1.5e-11 44.5 0.4 2.8e-11 43.7 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU84211.1 - 0.00013 22.5 0.1 0.00024 21.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EAU84211.1 - 0.045 13.1 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Rrn6 PF10214.9 EAU84211.1 - 0.62 8.5 4.0 0.84 8.0 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SR-25 PF10500.9 EAU84211.1 - 6 6.4 13.7 0.2 11.2 3.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cyclase PF04199.13 EAU84212.2 - 1.9e-25 89.7 0.0 2.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase PEPCK_ATP PF01293.20 EAU84212.2 - 0.18 10.4 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase zf-MYND PF01753.18 EAU84213.1 - 5.6e-07 29.5 10.3 1e-06 28.7 10.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EAU84213.1 - 0.72 10.0 3.5 1.1 9.5 2.0 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 VWA_2 PF13519.6 EAU84215.2 - 0.0001 22.9 0.0 0.00023 21.8 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain F-box-like PF12937.7 EAU84217.2 - 2.8e-06 27.1 0.1 9e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU84217.2 - 0.19 12.2 1.0 42 4.7 0.0 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) CNH PF00780.22 EAU84218.2 - 0.0041 16.8 0.0 0.75 9.3 0.0 2.2 2 0 0 2 2 2 2 CNH domain VWA_2 PF13519.6 EAU84219.1 - 0.00023 21.8 0.0 0.00076 20.1 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EAU84219.1 - 0.00054 20.1 0.0 0.00091 19.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EAU84219.1 - 0.0014 18.9 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Thr_synth_N PF14821.6 EAU84219.1 - 0.031 14.5 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonine synthase N terminus TRP PF06011.12 EAU84220.2 - 1.2e-26 93.4 20.0 1.4e-20 73.4 16.6 2.4 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EAU84220.2 - 0.00096 19.5 0.0 0.012 16.0 0.0 2.2 2 0 0 2 2 2 1 ML-like domain GFA PF04828.14 EAU84221.2 - 6.1e-13 48.9 1.7 4.7e-07 30.1 0.0 3.3 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme DUF1768 PF08719.11 EAU84223.2 - 1.7e-22 80.4 0.0 2.6e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 EAU84225.2 - 0.0022 18.3 0.0 0.007 16.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) DUF5096 PF17019.5 EAU84226.2 - 0.18 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) F-box-like PF12937.7 EAU84227.1 - 1.2e-08 34.7 0.8 1.2e-08 34.7 0.8 1.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU84228.2 - 1.5e-13 50.4 1.7 3.3e-13 49.3 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84228.2 - 0.0026 17.6 0.4 0.02 14.8 0.4 2.4 1 1 0 1 1 1 1 F-box domain RRM_1 PF00076.22 EAU84229.1 - 1.2e-24 85.9 0.1 2.4e-11 43.3 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EAU84229.1 - 0.00091 19.1 0.1 0.39 10.5 0.0 2.5 2 1 0 2 2 2 2 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 EAU84229.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EAU84229.1 - 0.0092 16.1 0.0 5.5 7.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EAU84229.1 - 0.063 13.2 0.0 89 3.1 0.0 3.6 4 0 0 4 4 4 0 Occluded RNA-recognition motif Ofd1_CTDD PF10637.9 EAU84230.2 - 1.3e-81 273.8 0.0 3e-79 266.0 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EAU84230.2 - 2.8e-32 111.3 0.0 1.2e-31 109.3 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EAU84230.2 - 1.5e-15 57.8 0.0 5.2e-15 56.1 0.0 2.0 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 EAU84231.2 - 1e-37 130.0 0.0 1.5e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 ATG22 PF11700.8 EAU84232.2 - 9.9e-98 327.8 26.4 5.5e-97 325.4 26.4 2.1 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EAU84232.2 - 1.2e-07 31.0 37.2 2.1e-06 26.9 7.8 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily V-ATPase_H_N PF03224.14 EAU84232.2 - 0.22 10.7 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H SPC25 PF06703.11 EAU84232.2 - 1.3 8.8 4.8 0.21 11.4 0.2 2.0 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) GST_N_3 PF13417.6 EAU84233.2 - 2.2e-18 66.4 0.0 4.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU84233.2 - 1.5e-15 57.3 0.0 4.5e-15 55.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF1768 PF08719.11 EAU84233.2 - 4.8e-10 39.9 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) GST_N PF02798.20 EAU84233.2 - 2.3e-07 31.1 0.0 5.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EAU84233.2 - 0.014 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C_2 PF13410.6 EAU84233.2 - 0.035 14.1 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Yip1 PF04893.17 EAU84233.2 - 0.18 11.5 4.8 0.39 10.4 4.8 1.6 1 0 0 1 1 1 0 Yip1 domain Frag1 PF10277.9 EAU84233.2 - 0.36 10.3 4.0 1.3 8.5 3.9 1.6 1 1 1 2 2 2 0 Frag1/DRAM/Sfk1 family F-box-like PF12937.7 EAU84234.2 - 6e-10 38.9 0.8 1.9e-09 37.3 0.8 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84234.2 - 0.11 12.4 0.7 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 F-box domain FlgN PF05130.12 EAU84235.2 - 0.00096 19.7 11.4 0.0084 16.6 0.1 3.1 3 0 0 3 3 3 1 FlgN protein BLOC1_2 PF10046.9 EAU84235.2 - 0.0066 16.7 5.0 0.0066 16.7 5.0 2.4 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5542 PF17696.1 EAU84235.2 - 0.041 14.0 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Atg14 PF10186.9 EAU84235.2 - 0.11 11.6 8.7 0.21 10.6 8.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RasGAP_C PF03836.15 EAU84235.2 - 0.12 12.6 12.4 0.14 12.3 1.3 3.5 3 1 1 4 4 4 0 RasGAP C-terminus Spc7 PF08317.11 EAU84235.2 - 0.19 10.5 17.9 0.058 12.3 10.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein MCRS_N PF13325.6 EAU84235.2 - 0.23 11.5 4.2 0.098 12.7 0.6 2.1 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein PEP-utilisers_N PF05524.13 EAU84235.2 - 0.25 11.5 3.5 2.2 8.5 1.6 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal TMCO5 PF14992.6 EAU84235.2 - 0.29 10.7 10.6 1.6 8.2 1.1 2.5 2 0 0 2 2 2 0 TMCO5 family Filament PF00038.21 EAU84235.2 - 0.4 10.2 14.5 0.56 9.7 7.5 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 EAU84235.2 - 0.92 9.6 12.2 0.81 9.7 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 EAU84235.2 - 0.97 8.2 11.0 0.099 11.5 3.0 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain TolA_bind_tri PF16331.5 EAU84235.2 - 1.2 9.2 18.2 0.1 12.7 5.5 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Hormone_1 PF00103.20 EAU84235.2 - 1.4 8.6 6.7 2.3 7.9 1.6 2.3 2 0 0 2 2 2 0 Somatotropin hormone family Herpes_UL6 PF01763.16 EAU84235.2 - 1.5 7.3 8.7 1.3 7.4 0.6 2.2 2 0 0 2 2 2 0 Herpesvirus UL6 like Golgin_A5 PF09787.9 EAU84235.2 - 1.8 8.0 20.0 0.16 11.4 12.1 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 EAU84235.2 - 2.5 8.2 21.2 5.5 7.1 11.3 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 EAU84235.2 - 2.5 7.6 11.7 0.27 10.8 3.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region HAUS-augmin3 PF14932.6 EAU84235.2 - 2.6 7.6 15.6 2 7.9 3.9 2.8 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 Phage_GPO PF05929.11 EAU84235.2 - 3 7.4 8.6 3.4 7.2 3.2 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase YabA PF06156.13 EAU84235.2 - 3.1 8.5 10.3 42 4.8 4.5 3.4 3 0 0 3 3 3 0 Initiation control protein YabA zf-CpG_bind_C PF12269.8 EAU84235.2 - 3.7 7.3 11.3 1.3 8.7 4.8 2.2 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain WXG100 PF06013.12 EAU84235.2 - 5 7.4 10.7 9.9 6.5 0.2 3.3 2 1 0 3 3 3 0 Proteins of 100 residues with WXG V_ATPase_I PF01496.19 EAU84235.2 - 5.5 4.8 6.6 1.5 6.7 2.4 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Syntaxin_2 PF14523.6 EAU84235.2 - 5.8 7.3 17.4 11 6.5 4.7 3.1 3 0 0 3 3 3 0 Syntaxin-like protein UPF0242 PF06785.11 EAU84235.2 - 6.2 6.9 16.4 2.8 8.0 7.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus eIF3_N PF09440.10 EAU84235.2 - 6.7 7.2 7.5 14 6.1 0.4 2.4 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain SLX9 PF15341.6 EAU84235.2 - 7 7.1 15.6 2.9 8.3 8.1 3.2 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 Sec34 PF04136.15 EAU84235.2 - 7 6.5 8.9 7.2 6.5 0.4 2.7 2 1 1 3 3 3 0 Sec34-like family DUF2203 PF09969.9 EAU84235.2 - 8.4 7.1 11.3 4.9 7.9 3.3 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 EAU84235.2 - 8.8 6.7 7.6 24 5.3 0.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4472 PF14739.6 EAU84235.2 - 9 7.1 16.3 5.3 7.8 7.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 EAU84235.2 - 9.5 6.8 29.1 6.6 7.3 12.6 3.5 2 1 1 3 3 3 0 Apg6 coiled-coil region CDC45 PF02724.14 EAU84236.2 - 5.6 5.1 30.7 1.3 7.2 4.9 2.4 2 0 0 2 2 2 0 CDC45-like protein Cyt-b5 PF00173.28 EAU84237.1 - 1.3e-23 82.9 0.0 1.7e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribonucleas_3_3 PF14622.6 EAU84240.2 - 4.6e-14 52.7 0.0 6.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EAU84240.2 - 2e-13 50.9 0.0 4.8e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EAU84240.2 - 1.5e-06 28.8 0.0 3.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif FAD_binding_4 PF01565.23 EAU84241.1 - 9.4e-31 106.4 5.0 9.4e-31 106.4 5.0 2.1 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 EAU84241.1 - 4.7e-07 29.8 0.0 9.4e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PAPS_reduct PF01507.19 EAU84242.1 - 3.2e-37 128.3 0.0 9.7e-37 126.7 0.0 1.7 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family TMEM135_C_rich PF15982.5 EAU84243.2 - 9.5e-05 23.0 1.5 5.2 7.7 0.1 3.4 2 1 1 3 3 3 3 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 EAU84243.2 - 0.09 13.2 1.2 9.5 6.6 0.1 3.3 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family F-box-like PF12937.7 EAU84245.2 - 9.9e-10 38.2 0.4 3.4e-09 36.5 0.4 2.0 1 0 0 1 1 1 1 F-box-like Ham1p_like PF01725.16 EAU84251.2 - 6.4e-56 189.2 0.0 7.3e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_M28 PF04389.17 EAU84252.1 - 2.3e-27 96.0 0.0 3.3e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAU84252.1 - 2.2e-07 30.8 0.1 4.9e-07 29.6 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L11 PF00298.19 EAU84253.1 - 6.2e-28 97.1 0.2 9.3e-28 96.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EAU84253.1 - 1.3e-27 95.4 0.6 2.5e-27 94.5 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain HisKA_2 PF07568.12 EAU84256.2 - 0.1 12.7 0.3 0.37 10.9 0.3 2.0 1 1 1 2 2 2 0 Histidine kinase Glyco_hydro_cc PF11790.8 EAU84257.1 - 7.6e-65 218.8 0.8 9.2e-65 218.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF4887 PF16228.5 EAU84257.1 - 3.4 7.8 10.5 4.5 7.4 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) RRM_1 PF00076.22 EAU84258.1 - 1.4e-30 104.9 0.1 6e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EAU84258.1 - 0.0017 18.3 0.1 0.43 10.6 0.0 2.3 2 0 0 2 2 2 2 DbpA RNA binding domain DUF4944 PF16302.5 EAU84258.1 - 0.011 15.7 0.6 1.2 9.2 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4944) RRM_5 PF13893.6 EAU84258.1 - 0.018 14.6 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAU84258.1 - 0.039 14.0 1.4 13 6.0 0.1 3.1 3 0 0 3 3 3 0 Limkain b1 Sigma70_ECF PF07638.11 EAU84258.1 - 0.073 13.0 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 ECF sigma factor OB_RNB PF08206.11 EAU84258.1 - 0.12 12.0 2.1 23 4.7 0.9 3.3 2 1 0 2 2 2 0 Ribonuclease B OB domain DUF1491 PF07372.12 EAU84258.1 - 0.32 11.4 1.6 0.45 10.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) DUF4187 PF13821.6 EAU84259.1 - 5e-23 80.6 1.2 1.2e-22 79.4 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EAU84259.1 - 9.9e-06 25.4 0.1 9.9e-06 25.4 0.1 2.9 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 EAU84259.1 - 0.15 12.2 0.9 1.1 9.4 0.2 2.6 2 0 0 2 2 2 0 G-patch domain DUF3425 PF11905.8 EAU84262.2 - 4e-15 55.9 0.4 2.9e-14 53.1 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EAU84262.2 - 1.1e-07 31.9 15.0 1.3e-07 31.6 7.4 3.0 2 1 0 2 2 2 1 bZIP transcription factor RtcB PF01139.17 EAU84262.2 - 0.0033 16.7 0.2 0.0049 16.1 0.2 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB bZIP_2 PF07716.15 EAU84262.2 - 0.0039 17.2 3.4 0.0039 17.2 3.4 2.9 3 0 0 3 3 3 2 Basic region leucine zipper DUF5101 PF17031.5 EAU84262.2 - 0.048 13.7 0.8 0.083 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5101) DLEU7 PF15760.5 EAU84262.2 - 0.062 12.8 1.3 0.14 11.7 1.3 1.5 1 0 0 1 1 1 0 Leukemia-associated protein 7 DUF3318 PF11780.8 EAU84262.2 - 0.21 11.5 3.1 7.7 6.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3318) Ribosomal_S14 PF00253.21 EAU84263.1 - 1.8e-23 82.1 0.5 3.1e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MFS_1 PF07690.16 EAU84264.2 - 5.6e-07 28.8 4.2 3.7e-05 22.8 0.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EAU84265.2 - 6.2e-72 242.1 0.0 8.3e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84265.2 - 5.7e-30 104.5 0.1 1e-27 97.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU84265.2 - 2.9e-09 36.7 0.5 2.5e-05 23.7 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAU84265.2 - 0.0019 17.0 0.1 0.0062 15.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EAU84265.2 - 0.032 14.2 0.0 1 9.2 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAU84265.2 - 0.07 12.5 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.17 EAU84266.2 - 2.6e-18 66.4 1.8 6.4e-18 65.2 0.0 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding SURF2 PF05477.11 EAU84266.2 - 0.016 14.9 4.4 0.029 14.1 4.4 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Spt20 PF12090.8 EAU84266.2 - 0.15 11.6 25.6 0.36 10.4 25.6 1.6 1 0 0 1 1 1 0 Spt20 family SKA1 PF07160.12 EAU84266.2 - 9.2 6.0 11.1 23 4.7 11.1 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 SNARE_assoc PF09335.11 EAU84267.2 - 1.2e-13 51.6 7.8 1.2e-13 51.6 7.8 2.3 2 1 1 3 3 3 1 SNARE associated Golgi protein Mucin-like PF16058.5 EAU84267.2 - 0.013 15.5 20.0 0.034 14.2 20.0 1.6 1 0 0 1 1 1 0 Mucin-like DUF2076 PF09849.9 EAU84268.2 - 0.16 12.0 0.1 0.18 11.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PEX11 PF05648.14 EAU84269.2 - 7.8e-13 48.4 2.6 1.5e-11 44.2 2.6 2.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.13 EAU84270.2 - 0.0027 17.9 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 Tctex-1 family Nop PF01798.18 EAU84273.1 - 2e-73 246.7 0.0 3.5e-73 245.9 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EAU84273.1 - 4.2e-37 127.7 6.3 1.1e-36 126.4 6.3 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain SoPB_HTH PF18090.1 EAU84273.1 - 0.02 15.0 0.1 0.84 9.8 0.1 2.9 2 0 0 2 2 2 0 Centromere-binding protein HTH domain NifU_N PF01592.16 EAU84274.1 - 3.3e-53 179.2 0.0 4e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain HTH_50 PF18024.1 EAU84274.1 - 0.012 15.2 0.1 0.038 13.6 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TFIID-31kDa PF02291.15 EAU84275.1 - 3.1e-20 72.5 0.0 4.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit WD40 PF00400.32 EAU84276.2 - 0.0058 17.5 0.3 3.3 8.7 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Mg_trans_NIPA PF05653.14 EAU84277.2 - 7.3e-51 173.0 18.6 1.7e-33 116.0 11.5 3.1 2 1 1 3 3 3 3 Magnesium transporter NIPA p450 PF00067.22 EAU84278.2 - 1.2e-57 195.7 0.0 1.6e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nup88 PF10168.9 EAU84279.2 - 2e-25 88.8 4.3 1.3e-12 46.5 0.0 2.9 2 1 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 EAU84279.2 - 0.0041 17.2 7.9 0.0041 17.2 7.9 2.8 3 1 1 4 4 4 1 Nucleoporin complex subunit 54 ExsD PF16806.5 EAU84279.2 - 0.082 12.8 2.2 0.18 11.7 2.2 1.5 1 0 0 1 1 1 0 Antiactivator protein ExsD BST2 PF16716.5 EAU84279.2 - 0.61 10.7 12.5 7.7 7.2 5.1 2.7 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 FliD_N PF02465.18 EAU84279.2 - 7.1 7.4 6.6 3 8.6 3.3 2.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Proteasome PF00227.26 EAU84280.2 - 7.8e-49 165.7 0.0 1.2e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAU84280.2 - 3.3e-12 45.8 0.2 6.4e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CSN8_PSD8_EIF3K PF10075.9 EAU84281.1 - 1.1e-33 116.3 0.2 1.7e-33 115.6 0.2 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EAU84281.1 - 2.8e-06 26.9 0.0 3.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 EAU84282.2 - 2.8e-31 108.5 0.0 3.4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit GFO_IDH_MocA PF01408.22 EAU84284.2 - 1.2e-19 71.3 0.1 2e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAU84284.2 - 3e-06 27.2 0.0 8.3e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sclerostin PF05463.11 EAU84284.2 - 0.0095 15.7 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 1 Sclerostin (SOST) MukB PF04310.12 EAU84284.2 - 0.023 14.5 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal TrkA_N PF02254.18 EAU84284.2 - 0.13 12.5 0.1 0.51 10.6 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain Cyt-b5 PF00173.28 EAU84286.1 - 3.7e-08 33.4 0.1 7.6e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.19 EAU84287.2 - 4.4e-42 143.1 0.0 1.2e-41 141.6 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EAU84287.2 - 2.8e-14 52.9 0.0 2.3e-07 30.8 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RNaseH_like PF04308.12 EAU84287.2 - 0.061 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease H-like Mrr_N PF14338.6 EAU84287.2 - 0.073 13.2 0.0 8.7 6.5 0.0 2.9 2 0 0 2 2 2 0 Mrr N-terminal domain TF_AP-2 PF03299.14 EAU84287.2 - 0.084 12.8 0.3 3.2 7.7 0.1 2.6 2 0 0 2 2 2 0 Transcription factor AP-2 Syntaxin PF00804.25 EAU84287.2 - 0.13 11.9 1.4 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Syntaxin DUF2458 PF10454.9 EAU84288.2 - 6.6e-06 25.9 1.2 1.3e-05 24.9 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 EAU84288.2 - 0.00053 19.7 0.2 0.001 18.7 0.2 1.4 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Arg_decarbox_C PF17944.1 EAU84288.2 - 0.062 13.9 1.3 0.088 13.4 0.1 1.9 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Hydrolase_4 PF12146.8 EAU84289.2 - 0.019 14.2 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 GDP_Man_Dehyd PF16363.5 EAU84290.2 - 6.5e-63 213.1 0.0 9.5e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EAU84290.2 - 1.4e-47 162.2 0.0 1.8e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAU84290.2 - 1.3e-09 37.5 0.0 1.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EAU84290.2 - 1.2e-07 31.2 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EAU84290.2 - 3.9e-07 29.5 0.1 0.003 16.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EAU84290.2 - 1.6e-06 27.5 0.5 0.0013 18.0 0.2 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Bystin PF05291.11 EAU84291.1 - 9.8e-129 428.8 0.0 1.2e-128 428.5 0.0 1.1 1 0 0 1 1 1 1 Bystin SnoaL_2 PF12680.7 EAU84292.2 - 0.00073 20.2 0.0 0.013 16.1 0.0 2.4 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EAU84292.2 - 0.0016 18.3 0.1 0.066 13.0 0.0 2.4 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase FAD_binding_3 PF01494.19 EAU84293.1 - 3.6e-22 79.1 0.0 7e-22 78.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAU84293.1 - 2.5e-05 23.7 1.0 0.00018 20.8 1.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU84293.1 - 2.8e-05 24.3 1.1 6.6e-05 23.1 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU84293.1 - 0.00043 19.4 0.1 0.00066 18.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EAU84293.1 - 0.0031 16.4 1.3 0.31 9.8 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase DAO PF01266.24 EAU84293.1 - 0.0047 16.5 3.9 0.0099 15.5 3.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EAU84293.1 - 0.0063 15.9 0.8 0.011 15.1 0.8 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAU84293.1 - 0.0076 15.4 3.2 0.022 13.9 3.2 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EAU84293.1 - 0.026 15.1 0.7 0.026 15.1 0.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAU84293.1 - 0.058 12.5 0.4 0.11 11.6 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EAU84293.1 - 0.75 8.4 3.0 0.92 8.1 1.9 1.9 2 1 0 2 2 2 0 HI0933-like protein Ribosomal_L3 PF00297.22 EAU84294.1 - 4.7e-185 614.8 8.4 5.3e-185 614.7 8.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_3 PF13812.6 EAU84295.2 - 4e-07 30.0 3.8 0.0032 17.5 0.0 4.5 4 1 2 6 6 6 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 EAU84295.2 - 1.5e-06 28.3 0.0 0.044 14.0 0.0 4.4 4 1 0 4 4 4 2 PPR repeat family PPR_1 PF12854.7 EAU84295.2 - 8.5e-05 22.2 2.1 0.062 13.0 0.5 3.8 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 EAU84295.2 - 0.11 11.9 0.0 5.9 6.2 0.0 2.3 1 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Ras PF00071.22 EAU84296.2 - 1.5e-41 141.7 0.0 1.5e-38 132.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAU84296.2 - 1.6e-28 99.3 0.0 2.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU84296.2 - 4.9e-09 35.9 0.0 1.1e-08 34.7 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAU84296.2 - 0.002 18.2 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAU84296.2 - 0.01 15.3 0.1 0.023 14.1 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DAO PF01266.24 EAU84299.1 - 1.1e-56 193.0 0.0 1.3e-56 192.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU84299.1 - 9.8e-05 22.5 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU84299.1 - 0.0018 17.6 0.0 0.0059 15.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU84299.1 - 0.033 13.2 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 EAU84299.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 EAU84299.1 - 0.11 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EAU84299.1 - 0.14 10.7 0.0 0.3 9.6 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 EAU84299.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Semialdhyde_dh PF01118.24 EAU84299.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NDUFA12 PF05071.16 EAU84300.1 - 2.1e-31 108.6 2.3 3e-31 108.1 2.3 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SH3_1 PF00018.28 EAU84301.2 - 5.7e-24 83.5 0.0 6e-11 41.8 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EAU84301.2 - 3.7e-16 58.7 0.0 3.3e-07 30.1 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 EAU84301.2 - 2.1e-15 56.1 0.0 5.6e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EAU84301.2 - 6.9e-06 26.0 0.0 1.6e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 EAU84301.2 - 0.0081 16.1 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 PB1 domain SOG2 PF10428.9 EAU84301.2 - 0.014 14.7 11.3 0.019 14.2 11.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Not3 PF04065.15 EAU84302.2 - 7.3e-90 300.4 29.2 1.2e-89 299.8 29.2 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EAU84302.2 - 1.9e-45 154.1 6.6 1.9e-45 154.1 6.6 2.9 5 0 0 5 5 5 1 NOT2 / NOT3 / NOT5 family SmpA_OmlA PF04355.13 EAU84302.2 - 0.051 13.4 0.4 0.51 10.2 0.4 2.6 1 1 0 1 1 1 0 SmpA / OmlA family DUF4407 PF14362.6 EAU84302.2 - 0.56 9.5 16.3 0.97 8.7 16.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 EAU84302.2 - 8.9 6.7 14.9 1.2 9.5 4.8 3.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cep57_MT_bd PF06657.13 EAU84302.2 - 9.4 6.8 14.4 15 6.1 3.3 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Ribosomal_L12 PF00542.19 EAU84303.2 - 2.2e-22 79.2 5.2 1.3e-20 73.5 3.8 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EAU84303.2 - 6.4e-15 54.6 1.6 6.4e-15 54.6 1.6 3.2 2 1 1 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain FliG_C PF01706.16 EAU84303.2 - 0.043 14.0 0.3 0.074 13.2 0.3 1.4 1 0 0 1 1 1 0 FliG C-terminal domain DUF5362 PF17319.2 EAU84303.2 - 0.24 11.2 0.1 1.1 9.2 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5362) Claudin_3 PF06653.11 EAU84304.2 - 7.2 6.5 12.7 3 7.8 1.8 2.8 2 1 0 2 2 2 0 Tight junction protein, Claudin-like GPHR_N PF12537.8 EAU84305.2 - 0.09 12.9 0.3 0.27 11.3 0.3 1.8 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF3180 PF11377.8 EAU84305.2 - 1.7 8.8 5.6 1.5 9.0 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) p450 PF00067.22 EAU84306.1 - 8.3e-51 173.2 0.0 1.1e-50 172.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COMPASS-Shg1 PF05205.12 EAU84307.2 - 5.7e-14 52.7 1.9 1.2e-13 51.6 1.8 1.5 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF445 PF04286.12 EAU84307.2 - 0.0083 16.0 0.8 0.011 15.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF445) EnY2 PF10163.9 EAU84307.2 - 0.057 13.8 0.2 0.21 12.0 0.0 1.8 1 1 1 2 2 2 0 Transcription factor e(y)2 URO-D PF01208.17 EAU84308.1 - 1.7e-131 438.5 0.0 1.9e-131 438.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF2520 PF10728.9 EAU84308.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) DSPn PF14671.6 EAU84309.2 - 8.5e-41 139.7 0.0 2e-39 135.2 0.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EAU84309.2 - 1.6e-14 53.8 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAU84309.2 - 0.00022 20.9 0.0 0.00056 19.6 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EAU84309.2 - 0.014 15.6 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ank_2 PF12796.7 EAU84310.2 - 7.2e-18 65.0 0.2 2.3e-08 34.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU84310.2 - 1.3e-15 57.5 1.6 4.9e-10 39.7 0.0 3.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EAU84310.2 - 6.4e-15 54.8 1.4 8.2e-05 22.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EAU84310.2 - 1.9e-12 46.2 0.6 0.00032 20.9 0.0 4.7 5 0 0 5 5 4 2 Ankyrin repeat Ank_5 PF13857.6 EAU84310.2 - 1.4e-10 41.2 0.9 0.00088 19.5 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EAU84310.2 - 0.00011 22.0 2.0 0.0024 17.7 0.1 3.3 2 2 1 3 3 3 1 KilA-N domain TMF_TATA_bd PF12325.8 EAU84310.2 - 0.0011 19.2 8.1 0.017 15.4 3.5 2.5 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding JAKMIP_CC3 PF16034.5 EAU84310.2 - 0.018 15.0 5.7 0.035 14.0 5.7 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Sec34 PF04136.15 EAU84310.2 - 0.031 14.2 5.3 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family Acyl-CoA_dh_C PF12806.7 EAU84310.2 - 0.1 12.8 1.4 0.65 10.2 0.0 2.6 3 0 0 3 3 2 0 Acetyl-CoA dehydrogenase C-terminal like RasGAP_C PF03836.15 EAU84310.2 - 0.14 12.3 7.3 1.4 9.0 1.9 2.3 2 0 0 2 2 2 0 RasGAP C-terminus UPF0449 PF15136.6 EAU84310.2 - 0.23 12.0 6.6 0.21 12.1 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 ABC_tran_Xtn PF12848.7 EAU84310.2 - 0.98 9.5 6.0 2.8 8.0 5.4 2.1 1 1 0 1 1 1 0 ABC transporter Bap31_Bap29_C PF18035.1 EAU84310.2 - 1.8 8.7 7.0 6.8 6.8 1.7 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain MscS_porin PF12795.7 EAU84310.2 - 2.6 7.5 17.3 2.9 7.4 11.0 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain GAS PF13851.6 EAU84310.2 - 3.1 7.1 11.1 0.93 8.8 2.9 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.13 EAU84310.2 - 3.6 7.7 7.8 8 6.6 0.3 2.5 2 0 0 2 2 2 0 DivIVA protein UPF0242 PF06785.11 EAU84310.2 - 4.9 7.2 7.7 2.3 8.3 2.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 EAU84310.2 - 8.2 6.6 15.8 2.1 8.5 0.4 3.2 3 1 0 3 3 3 0 TolA binding protein trimerisation Pept_S41_N PF18294.1 EAU84311.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Peptidase S41 N-terminal domain Hep_59 PF07052.11 EAU84311.1 - 0.46 11.3 6.0 0.9 10.3 6.0 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Nucleoside_tran PF01733.18 EAU84312.2 - 9.4e-41 140.2 3.2 9.4e-41 140.2 3.2 2.1 1 1 0 2 2 2 1 Nucleoside transporter Lig_chan PF00060.26 EAU84312.2 - 6.1 6.7 7.9 7.9 6.3 4.4 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel FAD_binding_4 PF01565.23 EAU84314.1 - 3.9e-33 114.1 4.0 7.6e-33 113.2 4.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU84314.1 - 5.6e-08 32.8 1.9 6.1e-08 32.6 0.2 1.9 2 0 0 2 2 2 1 Berberine and berberine like Zeta_toxin PF06414.12 EAU84314.1 - 0.062 12.6 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin MRC1 PF09444.10 EAU84315.2 - 4.5e-27 95.3 30.7 4.5e-27 95.3 30.7 6.7 5 2 2 7 7 7 1 MRC1-like domain Prim-Pol PF09250.11 EAU84315.2 - 0.053 13.9 0.8 4.2 7.7 0.2 2.9 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal Spore_III_AF PF09581.10 EAU84315.2 - 6.3 6.8 13.8 0.042 13.9 1.5 2.7 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Acyltransferase PF01553.21 EAU84316.2 - 5e-09 35.9 0.0 7.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Na_Ca_ex PF01699.24 EAU84317.2 - 4.3e-13 49.5 26.0 3.9e-07 30.1 6.2 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Glyco_hydro_88 PF07470.13 EAU84318.1 - 3.9e-21 75.5 0.1 5.4e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_18 PF00704.28 EAU84319.1 - 3.2e-67 227.5 0.0 3.9e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EAU84319.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Peptidase_M28 PF04389.17 EAU84320.2 - 2.3e-23 82.9 0.0 3.8e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAU84320.2 - 9.2e-06 25.5 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EAU84320.2 - 0.068 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Nicastrin Vac14_Fig4_bd PF11916.8 EAU84321.2 - 1.9e-79 265.5 7.6 3.3e-79 264.7 7.6 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EAU84321.2 - 4.5e-41 139.4 0.1 2.4e-37 127.4 0.0 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EAU84321.2 - 2.4e-09 36.6 0.4 0.049 13.9 0.0 6.1 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EAU84321.2 - 4.2e-06 27.1 0.1 2 9.0 0.0 5.7 4 2 2 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 EAU84321.2 - 5.4e-06 26.5 1.9 0.31 11.1 0.0 3.7 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAU84321.2 - 0.00028 21.2 0.0 9.1 6.8 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats CLASP_N PF12348.8 EAU84321.2 - 0.0016 18.1 1.1 15 5.0 0.0 4.5 5 1 0 5 5 5 1 CLASP N terminal SPX PF03105.19 EAU84321.2 - 0.1 12.5 2.5 0.13 12.2 0.8 1.9 2 0 0 2 2 2 0 SPX domain Y_phosphatase3 PF13350.6 EAU84322.2 - 7.5e-69 232.2 0.0 8.5e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EAU84322.2 - 0.032 13.8 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EAU84322.2 - 0.04 13.5 0.0 0.083 12.5 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Phage_TAC_3 PF06896.11 EAU84322.2 - 0.096 13.3 0.0 0.98 10.0 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC Filo_VP35 PF02097.15 EAU84322.2 - 0.17 11.0 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Filoviridae VP35 MCM PF00493.23 EAU84323.1 - 1.4e-104 348.1 0.3 2.2e-104 347.5 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAU84323.1 - 3.8e-38 130.2 0.1 7.2e-38 129.3 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EAU84323.1 - 5e-30 103.9 1.8 1.2e-29 102.7 1.8 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EAU84323.1 - 1e-24 86.7 1.9 3.2e-24 85.1 1.9 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAU84323.1 - 1.1e-23 83.7 1.6 2.6e-23 82.6 0.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAU84323.1 - 5.7e-08 32.4 0.0 8.8e-07 28.5 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EAU84323.1 - 0.0012 18.5 0.0 0.0045 16.7 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EAU84323.1 - 0.0017 18.2 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAU84323.1 - 0.021 14.8 0.0 0.082 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ank_2 PF12796.7 EAU84324.2 - 3.5e-52 174.9 11.5 6.4e-15 55.5 0.4 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Pex2_Pex12 PF04757.14 EAU84324.2 - 4.3e-46 157.3 8.2 6.3e-46 156.8 8.2 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Ank_4 PF13637.6 EAU84324.2 - 4.4e-33 113.2 12.4 2.4e-10 40.7 0.4 5.0 4 1 1 5 5 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU84324.2 - 1.8e-24 83.2 8.5 0.0029 18.0 0.1 7.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EAU84324.2 - 7.8e-21 73.9 19.3 1.6e-06 28.3 0.2 7.3 3 1 6 9 9 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAU84324.2 - 8.9e-20 70.2 14.5 0.011 16.2 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat SPX PF03105.19 EAU84324.2 - 8.5e-13 49.0 6.5 1e-09 38.8 0.0 3.1 2 1 1 3 3 3 2 SPX domain GDPD PF03009.17 EAU84324.2 - 4e-11 43.1 0.0 8.9e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-C3HC4_3 PF13920.6 EAU84324.2 - 1.1e-06 28.3 1.2 2.4e-06 27.3 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU84324.2 - 2.6e-05 23.9 1.5 6.5e-05 22.7 1.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU84324.2 - 0.00048 20.4 1.1 0.0015 18.8 1.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU84324.2 - 0.0015 18.6 2.6 0.0036 17.3 2.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EAU84324.2 - 0.04 14.1 2.4 0.087 13.0 2.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EAU84324.2 - 0.048 13.5 1.7 0.81 9.6 0.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EAU84324.2 - 0.097 12.6 1.9 0.21 11.5 1.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.13 EAU84324.2 - 0.12 12.6 1.3 0.25 11.5 1.3 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_5 PF14634.6 EAU84324.2 - 0.27 11.2 1.9 0.77 9.8 1.9 1.8 1 1 0 1 1 1 0 zinc-RING finger domain ABC_tran PF00005.27 EAU84325.2 - 5.6e-24 85.2 0.0 1.5e-23 83.8 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU84325.2 - 0.0008 19.3 0.4 0.0064 16.3 0.1 2.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 EAU84325.2 - 0.0013 18.5 0.0 0.0034 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU84325.2 - 0.0037 17.7 0.1 0.013 15.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EAU84325.2 - 0.012 15.1 0.0 0.29 10.5 0.1 2.9 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU84325.2 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EAU84325.2 - 0.016 15.8 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EAU84325.2 - 0.018 14.8 0.4 0.042 13.6 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EAU84325.2 - 0.026 14.8 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAU84325.2 - 0.026 15.0 0.0 0.048 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAU84325.2 - 0.031 13.6 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 EAU84325.2 - 0.041 13.9 0.0 18 5.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EAU84325.2 - 0.094 12.8 0.2 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 EAU84325.2 - 0.12 12.5 0.0 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EAU84325.2 - 0.14 11.0 0.0 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain RNF220 PF15926.5 EAU84327.2 - 2e-20 73.5 2.8 3.8e-20 72.6 2.8 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-Di19 PF05605.12 EAU84327.2 - 0.0052 17.0 1.3 1.7 9.0 0.1 3.3 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 EAU84327.2 - 0.25 11.2 1.8 3 7.8 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf_UBZ PF18439.1 EAU84327.2 - 0.6 9.8 3.7 1.6 8.3 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 EAU84327.2 - 1.2 9.7 5.7 2.6 8.6 0.0 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Tom7 PF08038.12 EAU84328.1 - 6.6e-23 80.1 0.3 7.4e-23 79.9 0.3 1.0 1 0 0 1 1 1 1 TOM7 family ETF_alpha PF00766.19 EAU84328.1 - 0.071 13.1 0.0 0.076 13.0 0.0 1.0 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain JAB PF01398.21 EAU84329.1 - 4.2e-25 88.0 0.1 7e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EAU84329.1 - 1.2e-18 67.5 0.1 2.2e-18 66.7 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.16 EAU84330.1 - 2.7e-27 96.0 1.2 3.8e-27 95.5 1.2 1.2 1 0 0 1 1 1 1 UreF AFG1_ATPase PF03969.16 EAU84331.2 - 3.1e-97 325.7 0.0 1.2e-93 314.0 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EAU84331.2 - 3.1e-05 24.4 0.0 0.034 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EAU84331.2 - 0.0055 17.0 0.0 0.026 14.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EAU84331.2 - 0.013 15.9 0.0 0.038 14.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAU84331.2 - 0.033 14.2 0.0 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EAU84331.2 - 0.052 13.0 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein Bac_DnaA PF00308.18 EAU84331.2 - 0.052 13.4 0.1 0.29 11.0 0.1 2.2 2 1 0 2 2 2 0 Bacterial dnaA protein TsaE PF02367.17 EAU84331.2 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SBDS PF01172.18 EAU84332.1 - 2.9e-20 72.1 0.0 3.6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FBD PF08387.10 EAU84332.1 - 0.027 14.4 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 FBD VRR_NUC PF08774.11 EAU84333.2 - 1e-22 80.2 0.0 2.4e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain DUF3263 PF11662.8 EAU84333.2 - 0.025 14.4 0.6 0.079 12.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) ArfGap PF01412.18 EAU84335.1 - 1.6e-15 57.2 1.6 2.5e-08 34.0 0.0 2.5 1 1 1 2 2 2 2 Putative GTPase activating protein for Arf Velvet PF11754.8 EAU84336.1 - 6.6e-64 216.2 3.4 5.8e-63 213.1 3.4 2.0 1 1 0 1 1 1 1 Velvet factor PPR_2 PF13041.6 EAU84337.1 - 2.1e-18 66.3 0.1 1.5e-06 28.3 0.0 7.0 6 2 2 8 8 8 2 PPR repeat family PPR PF01535.20 EAU84337.1 - 9.8e-18 63.1 0.0 0.056 13.7 0.0 9.8 12 0 0 12 12 12 5 PPR repeat PPR_3 PF13812.6 EAU84337.1 - 8e-10 38.7 0.1 0.012 15.6 0.0 6.3 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EAU84337.1 - 0.005 16.2 0.0 5.7 6.2 0.0 3.9 4 1 1 5 5 5 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EAU84337.1 - 0.0059 16.3 0.1 8.1 6.2 0.0 4.7 5 0 0 5 5 5 1 PPR repeat TPR_19 PF14559.6 EAU84337.1 - 0.0062 17.0 6.8 0.41 11.2 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat ATP13 PF12921.7 EAU84337.1 - 0.058 13.2 0.0 20 5.1 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial ATPase expression C8 PF08742.11 EAU84337.1 - 0.059 13.8 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 C8 domain DUF4817 PF16087.5 EAU84337.1 - 0.2 11.5 0.4 8.3 6.3 0.1 3.2 1 1 1 2 2 2 0 Helix-turn-helix domain (DUF4817) TPR_14 PF13428.6 EAU84337.1 - 0.35 11.8 9.3 24 6.1 0.1 7.3 9 1 1 10 10 10 0 Tetratricopeptide repeat HMG_box_2 PF09011.10 EAU84338.2 - 8.4e-15 55.1 13.3 1.3e-07 32.1 5.2 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 EAU84338.2 - 1.2e-14 54.5 15.7 8.5e-08 32.5 3.6 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box GRIM-19 PF06212.12 EAU84339.2 - 4.3e-31 107.6 0.1 7.9e-31 106.7 0.0 1.4 2 0 0 2 2 2 1 GRIM-19 protein bZIP_1 PF00170.21 EAU84340.2 - 0.065 13.3 3.9 0.17 12.0 3.9 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 EAU84340.2 - 0.84 9.4 3.2 1.5 8.6 3.2 1.4 1 0 0 1 1 1 0 Septum formation initiator SOR_SNZ PF01680.17 EAU84341.2 - 0.13 12.1 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 SOR/SNZ family Fer4 PF00037.27 EAU84342.1 - 2.2e-14 52.6 18.3 6.8e-09 35.2 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EAU84342.1 - 9.2e-13 48.6 10.5 1.5e-12 47.9 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAU84342.1 - 1.2e-10 42.1 10.2 4.9e-06 27.4 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EAU84342.1 - 1.1e-09 38.2 6.2 0.00023 21.2 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EAU84342.1 - 8.9e-09 35.4 10.7 1.4e-08 34.7 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EAU84342.1 - 1.1e-08 35.0 21.4 1.1e-06 28.6 12.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EAU84342.1 - 1.8e-07 30.9 18.4 0.00043 20.2 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EAU84342.1 - 5.5e-07 29.9 17.7 0.00027 21.3 10.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EAU84342.1 - 3.8e-06 26.7 12.2 0.0074 16.3 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EAU84342.1 - 4e-06 26.9 10.5 0.00029 21.1 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EAU84342.1 - 8.2e-05 23.1 10.5 0.022 15.3 12.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 EAU84342.1 - 0.0012 19.4 11.4 0.11 13.1 0.6 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 EAU84342.1 - 0.018 15.2 5.6 0.54 10.5 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EAU84342.1 - 0.021 15.0 9.0 0.8 9.9 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EAU84342.1 - 0.27 12.3 16.7 0.44 11.6 4.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EAU84342.1 - 0.36 11.7 12.8 1.7 9.6 1.5 2.7 2 1 2 4 4 4 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EAU84342.1 - 0.82 9.8 7.2 2.1 8.5 1.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Prefoldin_2 PF01920.20 EAU84343.1 - 2.1e-21 75.9 0.5 2.6e-21 75.6 0.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 EAU84343.1 - 0.013 15.5 1.0 0.023 14.8 0.7 1.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 TACC_C PF05010.14 EAU84343.1 - 0.022 14.5 0.3 3.9 7.2 0.0 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4924 PF16271.5 EAU84343.1 - 0.028 14.4 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) FlxA PF14282.6 EAU84343.1 - 0.043 13.8 1.4 8.8 6.4 0.9 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.6 EAU84343.1 - 0.07 12.5 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPACA9 PF15120.6 EAU84343.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 CAP PF00188.26 EAU84344.1 - 7.9e-16 59.0 0.0 1.2e-15 58.5 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family UPF0731 PF14982.6 EAU84344.1 - 0.14 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 UPF0731 family F-box-like PF12937.7 EAU84348.1 - 1.4e-06 28.1 0.1 3.2e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84348.1 - 5.5e-06 26.1 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EAU84348.1 - 0.0044 16.9 0.1 0.0082 16.0 0.1 1.4 1 0 0 1 1 1 1 F-box zf-C2H2 PF00096.26 EAU84349.1 - 2e-08 34.3 18.2 7.2e-06 26.2 0.3 4.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU84349.1 - 3.2e-07 30.5 1.5 3.2e-07 30.5 1.5 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU84349.1 - 1.7e-05 25.2 18.4 0.00029 21.4 0.2 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU84349.1 - 0.0002 21.6 0.7 0.4 11.0 0.0 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU84349.1 - 0.011 16.1 0.4 1.1 9.8 0.1 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EAU84349.1 - 0.11 12.5 2.3 0.14 12.2 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4451 PF14616.6 EAU84349.1 - 0.23 11.7 4.4 0.17 12.1 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-C2HE PF16278.5 EAU84349.1 - 0.31 11.5 2.2 0.32 11.5 0.6 1.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger UCH PF00443.29 EAU84350.1 - 6e-49 166.9 0.0 8.1e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAU84350.1 - 8.1e-22 78.2 0.0 2.6e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAU84350.1 - 0.0039 16.7 1.5 0.034 13.6 1.5 2.2 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.7 EAU84350.1 - 0.18 11.9 1.8 0.7 10.0 0.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon GFA PF04828.14 EAU84350.1 - 0.19 12.1 5.6 4.8 7.6 0.4 3.1 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme PP2C PF00481.21 EAU84351.2 - 8e-28 97.8 0.0 5.7e-25 88.4 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2914 PF11141.8 EAU84351.2 - 0.065 13.0 1.2 0.55 10.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) ACT_7 PF13840.6 EAU84353.2 - 2e-12 46.7 0.0 3.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain Castor1_N PF18700.1 EAU84353.2 - 0.0081 16.0 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Fer2_4 PF13510.6 EAU84354.2 - 0.17 12.0 0.0 2.9 8.0 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.25 EAU84355.1 - 8.5e-46 155.9 0.2 1.3e-45 155.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU84355.1 - 5.2e-31 108.0 0.0 7.6e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU84355.1 - 1.5e-12 47.8 1.1 3.8e-11 43.2 1.1 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU84355.1 - 0.089 12.2 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Trp_dioxygenase PF03301.13 EAU84356.2 - 0.2 10.9 0.1 0.3 10.4 0.1 1.1 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase Haspin_kinase PF12330.8 EAU84357.1 - 7.7e-55 186.3 0.0 1.1e-54 185.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Sld5 PF05916.11 EAU84358.2 - 1e-18 67.7 0.2 1.5e-18 67.2 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein MRVI1 PF05781.12 EAU84359.2 - 2.4 6.7 4.2 0.57 8.8 0.7 1.6 2 0 0 2 2 2 0 MRVI1 protein P21-Arc PF04062.14 EAU84360.2 - 2.8e-77 258.7 0.0 3.1e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.11 EAU84361.2 - 1e-29 102.5 0.9 1.7e-29 101.8 0.9 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EAU84361.2 - 3.9e-28 97.8 0.2 1e-27 96.4 0.0 1.8 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 EAU84361.2 - 0.025 14.2 1.5 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C2HC5 PF06221.13 EAU84361.2 - 0.084 12.9 1.8 0.17 11.9 1.8 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Nudix_N_2 PF14803.6 EAU84361.2 - 0.26 11.2 0.1 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Nudix N-terminal Iso_dh PF00180.20 EAU84362.1 - 6.6e-122 407.0 0.0 7.7e-122 406.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Alpha-amylase_C PF02806.18 EAU84363.1 - 4e-25 88.1 0.0 1.3e-24 86.4 0.0 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EAU84363.1 - 1.4e-19 70.2 0.0 3.1e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EAU84363.1 - 4.3e-15 56.1 0.3 1.3e-10 41.4 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF1732 PF08340.11 EAU84363.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) zf-C3HC4_3 PF13920.6 EAU84364.2 - 5.5e-07 29.4 12.9 8.4e-07 28.8 12.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU84364.2 - 1.8e-05 24.6 14.7 2.8e-05 24.0 14.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain KASH_CCD PF14662.6 EAU84364.2 - 0.00013 21.8 10.4 0.00013 21.8 10.4 1.8 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH zf-RING_2 PF13639.6 EAU84364.2 - 0.00017 21.8 14.3 0.00027 21.2 14.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU84364.2 - 0.00067 19.5 15.8 0.0011 18.7 15.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU84364.2 - 0.0011 18.8 14.9 0.0018 18.1 14.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU84364.2 - 0.0012 18.7 14.8 0.0027 17.5 10.0 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 ZapB PF06005.12 EAU84364.2 - 0.004 17.6 1.1 0.004 17.6 1.1 3.8 3 2 0 3 3 3 1 Cell division protein ZapB CENP-H PF05837.12 EAU84364.2 - 0.0046 17.3 7.6 0.0046 17.3 7.6 2.9 2 2 1 3 3 3 1 Centromere protein H (CENP-H) DivIC PF04977.15 EAU84364.2 - 0.029 14.1 2.0 0.029 14.1 2.0 3.4 3 1 1 4 4 4 0 Septum formation initiator UPF0029 PF01205.19 EAU84364.2 - 0.13 12.6 0.4 1.8 8.9 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein family UPF0029 zf-RING_4 PF14570.6 EAU84364.2 - 0.16 11.8 15.2 0.28 11.0 15.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EAU84364.2 - 0.28 11.3 13.1 0.52 10.4 13.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EAU84364.2 - 0.46 10.7 16.8 0.95 9.7 16.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Phage_GP20 PF06810.11 EAU84364.2 - 1.3 8.9 8.7 4.3 7.1 4.9 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 OmpH PF03938.14 EAU84364.2 - 3.5 8.0 10.4 1.2 9.4 4.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rep_fac-A_C PF08646.10 EAU84364.2 - 3.8 7.2 6.7 8.7 6.1 6.7 1.5 1 0 0 1 1 1 0 Replication factor-A C terminal domain Cep57_MT_bd PF06657.13 EAU84364.2 - 6.1 7.4 13.4 4.2 7.9 2.6 3.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 EAU84364.2 - 6.8 6.0 12.6 0.17 11.2 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RhoGEF PF00621.20 EAU84367.2 - 1.3e-22 80.9 0.0 1.1e-21 77.9 0.0 2.4 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 EAU84367.2 - 0.032 14.7 0.1 0.29 11.7 0.0 2.5 3 0 0 3 3 3 0 PH domain LRR_4 PF12799.7 EAU84369.2 - 4.3e-12 46.0 13.4 0.0025 18.2 0.6 7.1 5 2 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EAU84369.2 - 4.2e-08 32.6 17.7 0.28 11.3 0.3 7.7 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 EAU84369.2 - 0.00085 19.6 21.8 1.6 9.6 0.2 7.2 7 1 0 7 7 7 2 Leucine Rich Repeat Amidohydro_3 PF07969.11 EAU84370.1 - 4.3e-13 49.6 1.4 1.5e-07 31.3 0.1 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 EAU84370.1 - 2.9e-12 46.6 0.1 1.3e-08 34.5 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family HHH_2 PF12826.7 EAU84370.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3258 PF11646.8 EAU84370.1 - 0.19 11.8 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF3258 Myb_DNA-binding PF00249.31 EAU84371.2 - 8.6e-22 77.1 7.0 1e-11 44.8 0.1 4.3 4 1 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU84371.2 - 6.3e-17 61.6 3.2 9.6e-13 48.2 0.0 4.1 2 1 2 4 4 4 2 Myb-like DNA-binding domain MbeD_MobD PF04899.12 EAU84371.2 - 0.018 15.1 0.1 0.05 13.7 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like Rap1_C PF11626.8 EAU84371.2 - 0.3 11.2 2.5 0.28 11.3 0.2 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2052 PF09747.9 EAU84372.2 - 5.7e-07 29.9 20.5 1.8e-06 28.2 20.6 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) LcrV PF04792.12 EAU84372.2 - 0.18 11.1 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 V antigen (LcrV) protein DUF676 PF05057.14 EAU84374.2 - 7.3e-08 32.2 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAU84374.2 - 0.00089 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EAU84374.2 - 0.0063 17.1 12.8 0.013 16.2 12.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU84374.2 - 0.012 14.9 0.2 0.056 12.7 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EAU84374.2 - 0.015 15.2 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 EAU84374.2 - 0.02 14.4 0.0 0.069 12.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_3 PF07859.13 EAU84374.2 - 0.02 14.7 0.3 0.035 13.9 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EAU84374.2 - 0.06 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF915 PF06028.11 EAU84374.2 - 0.06 12.7 0.0 3.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Cyt_bd_oxida_II PF02322.15 EAU84374.2 - 0.061 12.7 0.4 0.1 11.9 0.4 1.3 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF2974 PF11187.8 EAU84374.2 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Acetyltransf_1 PF00583.25 EAU84375.1 - 1.1e-13 51.5 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU84375.1 - 4.6e-10 39.5 0.0 5.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU84375.1 - 3.9e-07 30.4 0.0 5.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU84375.1 - 4e-06 26.7 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EAU84375.1 - 0.00041 19.9 0.3 0.00041 19.9 0.3 1.5 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EAU84375.1 - 0.0065 16.5 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EAU84375.1 - 0.041 14.6 0.0 0.081 13.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PAF-AH_p_II PF03403.13 EAU84376.2 - 4.9e-13 48.3 0.0 6.3e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 EAU84376.2 - 0.00033 21.3 0.0 0.0004 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EAU84376.2 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase YjeF_N PF03853.15 EAU84377.2 - 3.2e-32 111.8 0.0 2.5e-30 105.6 0.0 2.1 1 1 0 1 1 1 1 YjeF-related protein N-terminus Abhydrolase_3 PF07859.13 EAU84378.2 - 3.1e-37 128.5 0.0 5.1e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU84378.2 - 4.2e-11 42.3 0.0 9.8e-11 41.1 0.0 1.5 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF664 PF04978.12 EAU84378.2 - 0.0024 18.3 0.5 0.89 10.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF664) COesterase PF00135.28 EAU84378.2 - 0.031 13.1 0.0 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Tubulin PF00091.25 EAU84379.1 - 1e-65 221.7 0.0 1.4e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAU84379.1 - 1.5e-49 167.4 0.0 2.5e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAU84379.1 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 EAU84379.1 - 0.13 12.1 0.0 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) Tubulin_2 PF13809.6 EAU84379.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin like tRNA-synt_1c PF00749.21 EAU84380.1 - 2.9e-109 364.8 0.0 4.1e-109 364.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EAU84380.1 - 6e-43 146.7 0.1 1e-42 145.9 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EAU84380.1 - 7.1e-31 107.4 0.0 1.5e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EAU84380.1 - 1.8e-08 35.2 4.6 8.4e-08 33.0 0.3 2.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 AAA PF00004.29 EAU84381.2 - 2.6e-21 76.4 0.0 7.3e-21 75.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EAU84381.2 - 0.0097 16.2 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAU84381.2 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EAU84381.2 - 0.087 13.2 0.6 5.2 7.4 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EAU84381.2 - 0.094 13.0 1.5 3 8.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain SANT_DAMP1_like PF16282.5 EAU84382.2 - 1.6e-26 92.3 3.9 3e-26 91.4 3.9 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EAU84382.2 - 0.03 14.2 7.9 0.089 12.7 4.8 2.8 3 1 0 3 3 3 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Tautomerase PF01361.21 EAU84382.2 - 0.21 11.5 0.6 0.59 10.1 0.6 1.7 1 0 0 1 1 1 0 Tautomerase enzyme DUF202 PF02656.15 EAU84383.1 - 1.3e-15 57.5 2.4 2.7e-15 56.6 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-U1 PF06220.12 EAU84384.1 - 1.6e-20 72.5 4.1 2.2e-20 72.1 4.1 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 EAU84384.1 - 0.11 12.4 1.5 0.17 11.8 1.5 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle LSM PF01423.22 EAU84385.1 - 3.2e-19 68.4 0.2 3.5e-19 68.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EAU84385.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain F-box-like PF12937.7 EAU84387.2 - 1.6e-10 40.7 1.3 3.6e-10 39.6 1.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU84387.2 - 2.1e-09 37.5 3.0 1.5 9.3 0.0 7.4 6 3 4 10 10 10 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EAU84387.2 - 2.8e-07 30.1 10.2 16 5.9 0.0 10.0 11 0 0 11 11 11 2 Leucine Rich repeat F-box PF00646.33 EAU84387.2 - 0.0001 22.1 0.3 0.00038 20.3 0.3 2.0 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EAU84387.2 - 0.34 10.7 4.6 7.2 6.5 0.0 4.1 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 EAU84388.2 - 1.1e-09 38.3 3.5 0.95 10.0 0.1 7.6 4 3 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAU84388.2 - 1.1e-05 25.3 0.2 1.1e+02 4.0 0.0 7.7 7 1 0 7 7 7 0 Leucine Rich Repeat F-box-like PF12937.7 EAU84388.2 - 2.1e-05 24.3 0.3 6.1e-05 22.8 0.3 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EAU84388.2 - 0.055 13.3 7.2 0.54 10.1 0.1 5.1 5 2 0 5 5 5 0 Leucine rich repeat F-box PF00646.33 EAU84388.2 - 0.11 12.5 0.2 0.64 10.0 0.2 2.4 1 0 0 1 1 1 0 F-box domain Lactamase_B_6 PF16661.5 EAU84389.1 - 1.3e-49 168.2 0.0 1.5e-46 158.3 0.0 2.5 1 1 1 2 2 2 2 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EAU84389.1 - 3.7e-25 89.1 9.0 5.5e-23 82.0 0.1 4.0 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EAU84389.1 - 9.1e-21 74.2 0.0 5e-20 71.8 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EAU84389.1 - 9.3e-06 25.5 0.0 2.8e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CDC45 PF02724.14 EAU84389.1 - 2 6.6 8.5 3.3 5.9 8.5 1.3 1 0 0 1 1 1 0 CDC45-like protein XRCC4 PF06632.12 EAU84389.1 - 5.7 5.7 9.1 1.3 7.8 3.9 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 LNS2 PF08235.13 EAU84390.1 - 6.1e-99 330.1 0.0 8.5e-99 329.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EAU84390.1 - 2e-36 124.0 0.0 5e-36 122.7 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 EAU84390.1 - 9.7e-07 28.9 0.2 3.7e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Acid_phosphat_B PF03767.14 EAU84390.1 - 0.15 11.6 0.2 0.48 10.0 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Complex1_LYR PF05347.15 EAU84391.1 - 1.1e-13 51.0 1.2 1.5e-13 50.6 1.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EAU84391.1 - 0.011 16.4 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like RRN3 PF05327.11 EAU84392.1 - 1.4e-202 674.2 0.0 1.4e-202 674.2 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EAU84392.1 - 0.014 13.6 19.1 0.04 12.2 8.8 2.2 2 0 0 2 2 2 0 Nop14-like family Na_trans_assoc PF06512.13 EAU84392.1 - 3.1 8.0 13.4 2.6 8.3 5.3 2.7 3 0 0 3 3 3 0 Sodium ion transport-associated SRP-alpha_N PF04086.13 EAU84393.1 - 6.3 6.6 7.0 10 6.0 7.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RRM_1 PF00076.22 EAU84394.1 - 2e-16 59.6 1.2 1e-15 57.3 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU84394.1 - 5.4e-07 29.6 0.0 7.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 EAU84394.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.4 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EAU84394.1 - 0.02 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EAU84394.1 - 0.14 12.0 0.0 4.3 7.3 0.0 2.3 2 1 0 2 2 2 0 Occluded RNA-recognition motif TFIID-18kDa PF02269.16 EAU84395.2 - 6.5e-21 74.2 0.1 1e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIA PF03153.13 EAU84395.2 - 0.76 9.7 2.7 0.71 9.8 2.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S10 PF00450.22 EAU84396.1 - 1.9e-93 314.2 0.0 2.3e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Stevor PF17410.2 EAU84396.1 - 0.027 14.0 0.1 0.048 13.2 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SAM_2 PF07647.17 EAU84396.1 - 0.039 14.1 0.0 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) RIFIN PF02009.16 EAU84396.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Rifin SKG6 PF08693.10 EAU84396.1 - 0.71 9.3 5.8 1.3 8.5 5.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GHMP_kinases_C PF08544.13 EAU84397.2 - 0.089 13.2 0.4 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1857 PF08982.11 EAU84399.2 - 1.1e-17 64.2 0.0 3.8e-17 62.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1857) GxDLY PF14607.6 EAU84399.2 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type Arrestin_N PF00339.29 EAU84400.2 - 0.0032 17.5 0.0 0.013 15.6 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 EAU84400.2 - 0.046 12.9 0.3 2.2 7.4 0.1 2.1 2 0 0 2 2 2 0 Rgp1 Abhydrolase_2 PF02230.16 EAU84403.1 - 5.3e-56 189.8 0.0 9.8e-56 189.0 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EAU84403.1 - 7e-07 30.1 0.0 8.8e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU84403.1 - 7.6e-06 25.4 0.0 0.00089 18.6 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EAU84403.1 - 8.1e-05 22.4 0.0 0.00013 21.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EAU84403.1 - 0.0056 16.6 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3700 PF12481.8 EAU84403.1 - 0.015 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Aluminium induced protein Abhydrolase_1 PF00561.20 EAU84403.1 - 0.021 14.4 0.3 1.2 8.7 0.0 2.4 2 1 1 3 3 3 0 alpha/beta hydrolase fold Esterase PF00756.20 EAU84403.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 EAU84403.1 - 0.041 13.4 0.0 0.32 10.5 0.0 2.0 1 1 1 2 2 2 0 Esterase PHB depolymerase DUF2048 PF09752.9 EAU84403.1 - 0.062 12.4 0.1 6.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 tRNA_m1G_MT PF01746.21 EAU84404.2 - 1.4e-28 100.0 0.0 5.8e-23 81.6 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DUF4106 PF13388.6 EAU84404.2 - 0.18 11.0 5.6 0.28 10.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DDRGK PF09756.9 EAU84404.2 - 3.5 7.2 12.9 5.9 6.4 12.9 1.3 1 0 0 1 1 1 0 DDRGK domain Methyltransf_23 PF13489.6 EAU84405.1 - 3.8e-11 43.1 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU84405.1 - 3.2e-08 34.1 0.0 7.2e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU84405.1 - 1.7e-06 28.6 0.0 3.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU84405.1 - 1.2e-05 25.9 0.0 2.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU84405.1 - 0.00024 21.0 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EAU84405.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.17 EAU84405.1 - 0.2 10.8 0.0 0.38 9.9 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family FOXP-CC PF16159.5 EAU84406.2 - 0.00054 20.5 12.3 0.0061 17.2 0.1 3.6 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EAU84406.2 - 0.04 14.1 1.0 0.64 10.1 0.1 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 EAU84406.2 - 0.11 12.8 2.8 0.35 11.2 2.8 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EAU84406.2 - 0.29 12.1 12.4 1.2 10.2 0.1 3.6 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU84406.2 - 0.85 10.2 0.0 0.85 10.2 0.0 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type RNA_pol_Rpb2_6 PF00562.28 EAU84409.2 - 7.9e-102 341.2 0.0 1.6e-101 340.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EAU84409.2 - 2.5e-33 115.3 0.0 5.6e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EAU84409.2 - 1.3e-27 95.8 0.0 3.3e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EAU84409.2 - 4.1e-23 82.0 0.0 1.1e-22 80.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EAU84409.2 - 2.4e-22 78.7 0.0 5.6e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EAU84409.2 - 2.5e-19 69.5 0.3 3e-15 56.4 0.1 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 GDPD PF03009.17 EAU84411.1 - 9.1e-30 104.2 0.1 2.3e-29 102.9 0.1 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EAU84411.1 - 0.00035 20.9 0.2 0.00035 20.9 0.2 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.21 EAU84412.2 - 2e-28 98.7 0.0 3.2e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MAGE_N PF12440.8 EAU84412.2 - 0.78 10.5 11.2 0.85 10.3 9.7 1.8 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Ribonuc_red_lgN PF00317.21 EAU84413.2 - 0.09 12.8 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain RRM_1 PF00076.22 EAU84414.2 - 1.9e-11 43.6 0.2 7.3e-07 28.9 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAS20 PF02064.15 EAU84415.2 - 2.7e-38 131.0 0.1 4.5e-38 130.3 0.1 1.3 1 0 0 1 1 1 1 MAS20 protein import receptor SET PF00856.28 EAU84415.2 - 8.8e-08 32.7 0.0 2.7e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EAU84415.2 - 0.047 14.3 0.2 8.3 7.1 0.0 2.9 2 0 0 2 2 2 0 SAF domain SMK-1 PF04802.15 EAU84416.2 - 3.8e-72 242.1 0.1 9.9e-72 240.8 0.1 1.7 1 1 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Baculo_LEF-10 PF07206.11 EAU84416.2 - 0.43 10.8 2.3 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) CLPTM1 PF05602.12 EAU84419.2 - 8.3e-154 512.7 0.0 9.8e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EAU84419.2 - 0.00046 19.9 0.3 0.0042 16.8 0.1 2.3 2 0 0 2 2 2 1 PQ loop repeat 2TM PF13239.6 EAU84419.2 - 2.3 8.6 7.9 0.76 10.1 1.0 2.9 3 0 0 3 3 3 0 2TM domain Tropomyosin_1 PF12718.7 EAU84420.1 - 0.045 13.9 2.2 0.066 13.4 2.2 1.2 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.20 EAU84420.1 - 0.095 12.1 5.5 0.13 11.6 5.5 1.1 1 0 0 1 1 1 0 Tropomyosin TSC22 PF01166.18 EAU84421.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family 14-3-3 PF00244.20 EAU84422.1 - 9.5e-108 358.8 3.3 1.1e-107 358.6 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EAU84422.1 - 0.32 11.5 2.6 0.63 10.6 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PLU-1 PF08429.11 EAU84425.2 - 5e-57 193.6 8.6 1.3e-56 192.2 5.1 3.0 3 1 1 4 4 4 1 PLU-1-like protein JmjC PF02373.22 EAU84425.2 - 1.1e-41 141.9 0.3 2.5e-41 140.7 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EAU84425.2 - 4.5e-19 68.9 0.1 2e-18 66.8 0.0 2.2 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EAU84425.2 - 4.1e-16 58.6 0.7 1.3e-15 57.1 0.7 1.9 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EAU84425.2 - 1.4e-14 54.2 10.7 1.4e-14 54.2 10.7 2.4 2 0 0 2 2 2 1 C5HC2 zinc finger PHD PF00628.29 EAU84425.2 - 2e-07 30.8 32.1 0.0016 18.3 0.2 4.7 4 0 0 4 4 4 2 PHD-finger MerR-DNA-bind PF09278.11 EAU84425.2 - 3.1 8.4 6.4 51 4.5 0.1 3.8 3 0 0 3 3 3 0 MerR, DNA binding CorA PF01544.18 EAU84426.1 - 2.5e-41 141.9 0.2 3.9e-41 141.3 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EAU84426.1 - 0.034 14.2 0.3 0.076 13.1 0.3 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus A_thal_3526 PF09713.10 EAU84426.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Spt20 PF12090.8 EAU84426.1 - 6.9 6.2 11.6 0.39 10.3 4.3 2.3 2 0 0 2 2 2 0 Spt20 family RCR PF12273.8 EAU84426.1 - 9.7 6.9 11.2 0.44 11.2 2.7 2.8 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red F-box-like PF12937.7 EAU84427.2 - 5.4e-08 32.6 1.5 2.5e-07 30.5 1.5 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU84427.2 - 3.2e-05 24.2 2.1 24 5.5 0.0 6.5 7 1 0 7 7 7 1 Leucine Rich repeats (2 copies) F-box PF00646.33 EAU84427.2 - 0.23 11.4 10.1 0.39 10.6 3.3 3.4 2 1 0 2 2 2 0 F-box domain Uds1 PF15456.6 EAU84429.1 - 3.5e-35 121.0 12.3 3.5e-35 121.0 12.3 6.4 3 2 2 5 5 5 1 Up-regulated During Septation HR1 PF02185.16 EAU84429.1 - 0.002 18.2 2.9 0.002 18.2 2.9 9.0 6 3 1 7 7 7 1 Hr1 repeat TOBE_3 PF12857.7 EAU84429.1 - 0.79 9.7 3.1 1.1 9.2 0.1 2.8 3 0 0 3 3 3 0 TOBE-like domain Tho1_MOS11_C PF18592.1 EAU84429.1 - 9.8 6.1 13.0 0.82 9.5 1.4 4.6 4 0 0 4 4 4 0 Tho1/MOS11 C-terminal domain VIR_N PF15912.5 EAU84430.1 - 2.8e-07 30.4 1.0 1.2e-06 28.4 0.6 2.0 1 1 0 1 1 1 1 Virilizer, N-terminal ORMDL PF04061.14 EAU84431.2 - 2.9e-45 153.4 0.8 3e-44 150.1 0.8 2.2 1 1 0 1 1 1 1 ORMDL family THF_DHG_CYH PF00763.23 EAU84432.1 - 1.7e-24 86.3 0.0 3.1e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EAU84432.1 - 1.8e-16 59.8 0.1 3.2e-08 33.0 0.0 2.7 1 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 EAU84432.1 - 0.025 13.5 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EAU84432.1 - 0.099 12.7 0.0 0.94 9.5 0.0 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase IPP-2 PF04979.14 EAU84433.1 - 8.4e-17 62.2 0.4 2.6e-16 60.6 0.4 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3246 PF11596.8 EAU84435.1 - 0.02 14.3 3.1 0.032 13.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) AAA PF00004.29 EAU84436.2 - 2.2e-48 164.0 0.0 2.1e-32 112.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAU84436.2 - 5.5e-10 39.6 0.4 0.0001 22.6 0.0 3.7 2 2 1 3 3 3 1 AAA domain AAA_lid_3 PF17862.1 EAU84436.2 - 4e-08 32.9 0.0 9e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 EAU84436.2 - 6.8e-08 32.6 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EAU84436.2 - 8.5e-08 32.8 1.0 0.015 15.7 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 EAU84436.2 - 9.6e-07 29.4 0.0 0.026 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EAU84436.2 - 1.8e-06 27.4 0.0 0.03 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 EAU84436.2 - 1.9e-06 27.9 0.0 0.0031 17.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EAU84436.2 - 2e-06 28.0 0.0 0.032 14.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EAU84436.2 - 2.1e-06 27.5 0.1 0.09 12.5 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 EAU84436.2 - 2.8e-06 27.0 0.1 7.8e-05 22.4 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.14 EAU84436.2 - 1.4e-05 25.3 0.0 0.0013 18.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EAU84436.2 - 1.7e-05 25.2 0.0 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EAU84436.2 - 3.8e-05 23.7 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAU84436.2 - 5e-05 22.8 0.4 0.015 14.7 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EAU84436.2 - 9.6e-05 22.2 0.4 0.42 10.3 0.2 2.6 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EAU84436.2 - 0.00024 20.9 0.4 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.11 EAU84436.2 - 0.00029 20.7 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EAU84436.2 - 0.00031 20.1 0.1 0.28 10.4 0.0 2.6 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EAU84436.2 - 0.00038 20.7 0.0 0.84 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAU84436.2 - 0.0012 18.6 0.2 0.2 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EAU84436.2 - 0.0015 18.3 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EAU84436.2 - 0.0016 19.0 0.3 0.1 13.1 0.1 2.5 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 EAU84436.2 - 0.0036 17.2 2.5 1.9 8.4 0.1 3.1 4 0 0 4 4 3 2 NACHT domain AAA_7 PF12775.7 EAU84436.2 - 0.0038 16.8 0.3 0.15 11.6 0.0 2.5 3 0 0 3 3 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 EAU84436.2 - 0.004 16.4 0.3 0.6 9.2 0.2 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 EAU84436.2 - 0.0047 16.5 3.2 6.7 6.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 EAU84436.2 - 0.01 15.2 0.1 0.82 8.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin CPT PF07931.12 EAU84436.2 - 0.013 15.4 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 EAU84436.2 - 0.018 14.4 7.5 0.24 10.7 0.2 3.7 3 1 1 4 4 4 0 KaiC ResIII PF04851.15 EAU84436.2 - 0.021 14.8 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SKI PF01202.22 EAU84436.2 - 0.022 14.9 0.0 0.86 9.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Parvo_NS1 PF01057.17 EAU84436.2 - 0.025 13.7 0.1 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 EAU84436.2 - 0.026 14.9 0.7 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EAU84436.2 - 0.034 14.6 0.1 4.9 7.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EAU84436.2 - 0.048 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 EAU84436.2 - 0.068 13.4 0.7 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF1657 PF07870.11 EAU84436.2 - 0.076 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) PhoH PF02562.16 EAU84436.2 - 0.15 11.5 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein STIMATE PF12400.8 EAU84437.1 - 5.5e-36 123.9 2.4 5.5e-36 123.9 2.4 1.5 2 0 0 2 2 2 1 STIMATE family DUF2009 PF09418.10 EAU84438.1 - 4.3e-213 708.4 0.0 4.9e-213 708.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 EAU84438.1 - 7.8e-07 29.1 3.6 1.4e-06 28.3 3.6 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 EAU84438.1 - 0.0098 16.1 2.7 0.023 15.0 2.7 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 EAU84438.1 - 0.1 12.5 3.5 0.19 11.6 3.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pro-kuma_activ PF09286.11 EAU84439.1 - 1.8e-38 132.1 0.1 3e-38 131.3 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EAU84439.1 - 0.00016 21.0 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family eIF3m_C_helix PF18005.1 EAU84440.1 - 4.8e-12 45.4 2.1 4.8e-12 45.4 2.1 2.0 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 EAU84440.1 - 7.5e-11 42.5 0.1 6.7e-10 39.4 0.0 2.4 2 1 0 2 2 2 1 PCI domain NA37 PF04245.13 EAU84440.1 - 0.0077 15.7 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 37-kD nucleoid-associated bacterial protein DUF1804 PF08822.11 EAU84440.1 - 0.022 14.7 0.3 0.78 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Hep_59 PF07052.11 EAU84441.2 - 9.4e-28 97.1 1.7 9.4e-28 97.1 1.7 2.2 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DLIC PF05783.11 EAU84443.2 - 2.4e-42 145.4 0.6 4e-38 131.5 0.0 3.1 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 EAU84443.2 - 6e-05 23.2 0.0 0.00024 21.3 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EAU84443.2 - 0.014 15.8 0.1 0.076 13.4 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EAU84443.2 - 0.047 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EAU84443.2 - 0.053 14.1 0.0 0.17 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EAU84443.2 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EAU84443.2 - 0.081 12.4 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Dynamin_N PF00350.23 EAU84443.2 - 0.13 12.3 0.0 0.64 10.1 0.1 1.9 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 EAU84443.2 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP41 PF04176.13 EAU84444.2 - 1.2e-59 200.6 0.0 1.5e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family TFIID_20kDa PF03847.13 EAU84445.1 - 1.8e-28 98.8 0.2 3e-28 98.1 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EAU84445.1 - 0.0002 21.6 0.0 0.00063 20.0 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EAU84445.1 - 0.0092 16.1 0.2 0.037 14.1 0.0 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EAU84445.1 - 0.013 15.6 2.1 0.088 12.9 0.0 3.0 3 1 0 3 3 3 0 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EAU84445.1 - 0.031 14.6 1.9 0.048 14.0 0.0 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 RRS1 PF04939.12 EAU84446.2 - 4.8e-59 198.9 6.0 4.8e-59 198.9 6.0 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) RPW8 PF05659.11 EAU84446.2 - 0.054 13.2 0.3 0.095 12.4 0.3 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FAD_binding_4 PF01565.23 EAU84447.2 - 4.5e-27 94.5 2.5 6.8e-27 93.9 2.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU84447.2 - 1.7e-05 24.8 0.1 6.7e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Btz PF09405.10 EAU84449.1 - 4e-10 40.1 8.7 4e-10 40.1 8.7 2.7 3 1 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding Lge1 PF11488.8 EAU84450.2 - 0.04 14.1 0.6 0.079 13.2 0.6 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Phos_pyr_kin PF08543.12 EAU84451.1 - 2.4e-83 279.3 2.3 7.6e-62 208.9 2.4 2.2 1 1 1 2 2 2 2 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EAU84451.1 - 5.3e-44 150.5 0.0 7.6e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 EAU84451.1 - 2e-06 27.3 2.4 0.026 13.8 0.2 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase PDE8 PF08629.10 EAU84451.1 - 0.13 12.3 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 PDE8 phosphodiesterase Carb_kinase PF01256.17 EAU84451.1 - 0.15 11.5 6.0 0.13 11.7 1.7 2.4 2 1 0 2 2 2 0 Carbohydrate kinase UPF0029 PF01205.19 EAU84452.2 - 6.8e-32 109.9 0.0 1.2e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EAU84452.2 - 6.1e-07 29.7 0.0 1.2e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 RWD domain Aldedh PF00171.22 EAU84453.2 - 3.2e-161 536.9 1.7 3.7e-161 536.7 1.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ldh_2 PF02615.14 EAU84453.2 - 0.071 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase FAA_hydrolase PF01557.18 EAU84454.1 - 5.5e-61 206.0 0.0 7.1e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Coiled-coil_56 PF09813.9 EAU84457.1 - 2.8e-07 30.5 0.0 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 TOM6p PF15184.6 EAU84457.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog DUF4514 PF14986.6 EAU84457.1 - 0.074 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) HSP9_HSP12 PF04119.12 EAU84457.1 - 0.15 12.5 1.7 0.23 11.9 1.7 1.3 1 0 0 1 1 1 0 Heat shock protein 9/12 DUF1556 PF07590.11 EAU84458.2 - 2.1 8.7 4.5 0.74 10.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) GCP_N_terminal PF17681.1 EAU84459.2 - 3.6e-36 125.4 0.0 5.6e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EAU84459.2 - 1.8e-34 119.6 4.6 1.8e-34 119.6 4.6 2.1 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal DUF3379 PF11859.8 EAU84460.2 - 0.072 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) End3 PF12761.7 EAU84460.2 - 1.2 9.2 4.7 11 6.1 4.7 2.0 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 RRM_1 PF00076.22 EAU84461.2 - 2e-19 69.2 0.0 3.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU84461.2 - 1.6e-07 31.3 0.0 3.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EAU84461.2 - 0.0005 19.7 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 PF05764.13 EAU84461.2 - 0.0068 16.6 14.0 0.01 16.0 14.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein PcfK PF14058.6 EAU84461.2 - 0.0076 16.5 9.3 0.012 15.9 9.3 1.3 1 0 0 1 1 1 1 PcfK-like protein DDRGK PF09756.9 EAU84461.2 - 0.056 13.0 10.9 0.095 12.3 10.9 1.3 1 0 0 1 1 1 0 DDRGK domain Nup35_RRM_2 PF14605.6 EAU84461.2 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Presenilin PF01080.17 EAU84461.2 - 0.22 10.3 2.0 0.26 10.0 2.0 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EAU84461.2 - 0.34 10.7 8.1 0.48 10.2 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 EAU84461.2 - 1.1 9.3 22.0 1.8 8.6 22.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 EAU84461.2 - 3.2 5.9 12.7 4.8 5.3 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 EAU84461.2 - 7.6 6.2 6.9 12 5.6 6.9 1.2 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 EAU84462.2 - 1.8e-212 707.0 0.0 2.1e-212 706.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EAU84462.2 - 0.0018 17.8 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 2 NMDA receptor-regulated gene protein 2 C-terminus Rhomboid PF01694.22 EAU84463.2 - 6.3e-07 29.5 8.3 9.9e-07 28.9 8.3 1.3 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.16 EAU84463.2 - 2.6e-05 23.8 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain DER1 PF04511.15 EAU84463.2 - 0.00019 21.4 5.1 0.00027 20.9 5.1 1.1 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 EAU84463.2 - 0.0021 18.6 0.4 0.0042 17.6 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) ING PF12998.7 EAU84464.2 - 1.1e-08 35.5 0.0 2.1e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EAU84464.2 - 3.3e-06 26.9 9.3 5.6e-06 26.2 9.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EAU84464.2 - 0.0057 16.8 0.2 0.011 15.9 0.2 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EAU84464.2 - 0.006 16.8 1.6 0.011 15.9 1.6 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Rubredoxin PF00301.20 EAU84464.2 - 0.039 14.0 3.9 0.05 13.6 1.3 2.4 2 0 0 2 2 2 0 Rubredoxin PHD_2 PF13831.6 EAU84464.2 - 0.29 10.7 3.1 0.58 9.8 3.1 1.5 1 0 0 1 1 1 0 PHD-finger GATA PF00320.27 EAU84465.1 - 3e-08 33.1 4.2 6.8e-08 32.0 4.2 1.7 1 0 0 1 1 1 1 GATA zinc finger CCDC106 PF15794.5 EAU84466.1 - 0.084 12.6 0.8 0.12 12.0 0.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Mucin PF01456.17 EAU84466.1 - 1.1 9.3 7.7 1.9 8.4 7.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF810 PF05664.11 EAU84468.2 - 0.11 11.1 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Pkinase PF00069.25 EAU84471.2 - 7.2e-28 97.7 0.0 1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84471.2 - 9.6e-15 54.6 0.2 1.5e-13 50.6 0.2 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU84471.2 - 0.02 13.7 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RVP_2 PF08284.11 EAU84488.2 - 1.9e-06 27.7 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EAU84488.2 - 1.7e-05 25.4 0.0 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EAU84488.2 - 0.00015 22.3 0.0 0.00032 21.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 EAU84488.2 - 0.003 17.6 1.1 0.007 16.4 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EAU84488.2 - 0.037 13.9 2.0 0.1 12.4 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Imm74 PF15603.6 EAU84488.2 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 74 zf-CCHC_2 PF13696.6 EAU84488.2 - 0.19 11.6 0.8 0.53 10.2 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF2433 PF10360.9 EAU84492.2 - 1.6e-46 157.5 0.0 4.7e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2433) RRM_1 PF00076.22 EAU84492.2 - 0.0045 16.8 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EAU84492.2 - 0.0066 17.0 0.0 0.014 15.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU84492.2 - 0.067 13.4 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Med13_C PF06333.12 EAU84493.2 - 6.2e-49 167.0 4.2 6.2e-49 167.0 4.2 3.3 3 1 1 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EAU84493.2 - 1.6e-31 109.9 0.7 1.6e-31 109.9 0.7 2.3 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Acyl-CoA_dh_1 PF00441.24 EAU84495.1 - 3.4e-43 147.4 3.5 4.9e-43 146.9 3.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EAU84495.1 - 3.4e-28 98.6 0.5 1.6e-27 96.4 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EAU84495.1 - 4e-22 78.2 0.0 7.6e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAU84495.1 - 2.2e-20 73.3 0.6 4.6e-20 72.3 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain COMMD1_N PF17221.3 EAU84495.1 - 0.037 14.3 0.6 0.99 9.7 0.1 2.5 1 1 1 2 2 2 0 COMMD1 N-terminal domain Acyl-CoA_ox_N PF14749.6 EAU84495.1 - 0.045 14.3 0.0 0.083 13.5 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal adh_short_C2 PF13561.6 EAU84496.1 - 3.8e-64 216.5 0.0 4.5e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU84496.1 - 1.7e-45 154.9 0.0 2.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU84496.1 - 1.2e-05 25.3 0.2 2.5e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF962 PF06127.11 EAU84497.1 - 4.6e-23 81.1 2.5 2.2e-22 78.9 2.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Osw5 PF17062.5 EAU84497.1 - 5.4 7.2 9.4 1.2 9.3 5.1 2.0 2 0 0 2 2 2 0 Outer spore wall 5 Longin PF13774.6 EAU84498.1 - 4.3e-25 87.6 0.1 7e-25 86.9 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EAU84498.1 - 1.3e-14 53.8 0.0 2.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Nab1 PF04902.12 EAU84498.1 - 0.032 14.6 0.3 0.054 13.9 0.3 1.3 1 0 0 1 1 1 0 Conserved region in Nab1 SLM4 PF16818.5 EAU84498.1 - 0.041 13.8 0.1 0.088 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein SLM4 DUF4646 PF15496.6 EAU84499.1 - 3.3e-11 43.9 1.2 2.2e-08 34.8 0.2 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4646) XRN_M PF17846.1 EAU84500.2 - 8.6e-147 489.7 0.6 5.3e-108 361.8 0.1 2.6 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 EAU84500.2 - 8e-92 307.0 0.1 3.3e-91 305.0 0.1 1.9 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 EAU84500.2 - 0.00023 21.1 2.4 0.0005 20.0 2.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EAU84500.2 - 0.021 14.8 1.0 0.042 13.8 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EAU84500.2 - 0.11 12.4 4.6 0.079 12.8 1.6 2.1 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 EAU84500.2 - 0.37 11.2 0.0 0.37 11.2 0.0 2.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G IF-2B PF01008.17 EAU84501.1 - 6.7e-81 271.6 0.0 8.2e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family GA-like PF17573.2 EAU84501.1 - 0.12 12.4 0.5 0.27 11.2 0.5 1.6 1 0 0 1 1 1 0 GA-like domain YihI PF04220.12 EAU84501.1 - 6.3 6.5 8.1 10 5.8 8.1 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) MTP18 PF10558.9 EAU84502.1 - 6.7e-65 218.2 5.2 1.2e-63 214.2 5.2 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Forkhead PF00250.18 EAU84503.1 - 1.1e-24 86.5 0.0 1.9e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EAU84503.1 - 2.8e-05 24.4 0.0 6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain BCAS3 PF12490.8 EAU84503.1 - 0.12 11.9 5.4 0.22 11.0 5.4 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 BRF1 PF07741.13 EAU84503.1 - 4.7 7.6 6.5 10 6.5 0.5 2.8 3 0 0 3 3 3 0 Brf1-like TBP-binding domain IPK PF03770.16 EAU84505.1 - 2.6e-51 174.3 0.0 3.9e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Sigma70_ner PF04546.13 EAU84511.2 - 0.21 11.5 1.0 0.35 10.7 1.0 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cactin_mid PF10312.9 EAU84512.1 - 3.5e-63 212.9 8.1 3.5e-63 212.9 8.1 3.1 3 1 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EAU84512.1 - 3.2e-60 201.6 7.1 6.2e-60 200.6 7.1 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein AAA_2 PF07724.14 EAU84513.2 - 1.1e-35 123.3 0.0 1.9e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EAU84513.2 - 2.3e-10 41.0 0.0 5.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EAU84513.2 - 1.7e-07 31.2 0.0 3.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein HeH PF12949.7 EAU84513.2 - 0.17 11.6 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain Ran_BP1 PF00638.18 EAU84514.2 - 6.2e-50 168.6 0.4 1.2e-49 167.7 0.4 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EAU84514.2 - 8e-06 25.8 0.2 4.9e-05 23.2 0.2 1.9 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.14 EAU84514.2 - 0.00016 21.4 0.7 0.00021 21.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) PBP_sp32 PF07222.12 EAU84514.2 - 0.86 9.0 8.3 1.2 8.5 8.3 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GOLD_2 PF13897.6 EAU84514.2 - 1.7 9.1 9.4 7.6 7.0 5.5 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking SAPS PF04499.15 EAU84514.2 - 2.8 6.6 10.2 3.4 6.3 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_Rpc4 PF05132.14 EAU84514.2 - 5.8 7.3 10.1 9.2 6.7 10.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 EMP24_GP25L PF01105.24 EAU84515.2 - 1.1e-50 172.1 0.0 1.3e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin PF00225.23 EAU84516.2 - 8.7e-87 291.1 0.4 3.6e-73 246.4 0.1 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EAU84516.2 - 5.2e-10 39.5 0.0 1.7e-06 28.0 0.0 2.6 1 1 1 2 2 2 2 Microtubule binding DUF4094 PF13334.6 EAU84516.2 - 0.17 12.3 0.8 0.51 10.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) GAS PF13851.6 EAU84516.2 - 0.18 11.1 8.0 0.59 9.4 0.2 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 EAU84516.2 - 1.6 9.0 9.2 1.5 9.1 1.6 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 EAU84516.2 - 4.3 8.0 5.9 3.3 8.4 1.6 2.5 2 0 0 2 2 2 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 EAU84516.2 - 4.5 7.9 10.0 9.1 7.0 1.7 2.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 EAU84516.2 - 9.8 6.7 8.8 9.6 6.7 1.4 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Amidohydro_2 PF04909.14 EAU84517.1 - 3.7e-08 33.5 0.1 3.8e-07 30.2 0.0 2.0 1 1 0 2 2 2 1 Amidohydrolase FAD_binding_6 PF00970.24 EAU84518.2 - 5.7e-08 33.0 0.0 1.1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EAU84518.2 - 2.7e-07 31.2 0.0 4.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EAU84518.2 - 0.00017 21.7 0.0 0.00023 21.3 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain zf-H2C2_2 PF13465.6 EAU84519.2 - 6.1e-05 23.3 12.5 0.0066 16.8 1.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EAU84519.2 - 0.00019 21.7 0.8 0.00019 21.7 0.8 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU84519.2 - 0.00049 20.7 16.7 0.026 15.4 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HE PF16278.5 EAU84519.2 - 0.6 10.6 2.9 7.8 7.0 0.7 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4366 PF14283.6 EAU84522.1 - 0.27 11.3 0.0 0.5 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Med18 PF09637.10 EAU84523.1 - 1.2e-08 35.1 0.0 1.3e-07 31.7 0.0 1.9 1 1 1 2 2 2 2 Med18 protein Cyclin_N PF00134.23 EAU84525.1 - 0.036 13.8 0.0 0.093 12.5 0.0 1.8 1 1 0 1 1 1 0 Cyclin, N-terminal domain QslA_E PF18226.1 EAU84526.2 - 0.096 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E Cyclin PF08613.11 EAU84529.1 - 3e-05 24.5 0.0 5.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.8 EAU84530.1 - 7.1e-123 411.1 0.2 2.7e-121 405.9 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EAU84530.1 - 3.8e-79 265.9 0.0 5.6e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Forkhead PF00250.18 EAU84531.2 - 5.2e-31 106.8 0.0 8.2e-31 106.1 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain CIAPIN1 PF05093.13 EAU84532.1 - 1.1e-31 109.3 3.5 2.1e-31 108.4 3.5 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EAU84532.1 - 6.3e-07 29.7 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus zf-HIT PF04438.16 EAU84533.2 - 2e-05 24.3 12.0 3.2e-05 23.7 12.0 1.3 1 0 0 1 1 1 1 HIT zinc finger Cwf_Cwc_15 PF04889.12 EAU84533.2 - 2.1 8.0 16.2 0.49 10.1 11.7 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Arf PF00025.21 EAU84534.1 - 4.6e-72 241.1 0.0 5.3e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAU84534.1 - 2.9e-15 56.2 0.0 3.9e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAU84534.1 - 3.3e-14 52.8 0.1 3.5e-09 36.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EAU84534.1 - 9.4e-14 51.7 0.0 1.2e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU84534.1 - 1.8e-10 40.6 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAU84534.1 - 1.5e-09 37.6 0.0 1.9e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU84534.1 - 0.00032 20.8 0.0 0.00054 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOG1 PF06858.14 EAU84534.1 - 0.047 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) WD40 PF00400.32 EAU84535.2 - 1.8e-19 69.7 11.0 0.00016 22.4 0.8 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84535.2 - 3.6e-10 40.0 0.8 2.8e-05 24.3 0.2 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAU84535.2 - 0.026 14.4 0.0 0.066 13.1 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF1481 PF07356.12 EAU84535.2 - 0.045 13.5 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) Iso_dh PF00180.20 EAU84536.1 - 1.2e-97 327.2 0.0 1.4e-97 327.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2373 PF10180.9 EAU84538.2 - 7.6e-20 70.5 0.8 1.4e-19 69.7 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Aminotran_1_2 PF00155.21 EAU84539.1 - 3.1e-74 250.3 0.0 4.3e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EAU84539.1 - 1.4e-05 23.8 0.0 2.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EAU84539.1 - 0.001 18.1 1.1 0.0017 17.4 0.0 1.9 3 0 0 3 3 3 1 Aminotransferase class-V Preseq_ALAS PF09029.10 EAU84539.1 - 2.3 8.8 13.3 9.5e+02 0.3 13.3 2.8 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence RTC4 PF14474.6 EAU84543.2 - 2.9e-08 33.9 0.0 6.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain SOG2 PF10428.9 EAU84543.2 - 0.62 9.2 25.3 0.91 8.6 25.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 EAU84543.2 - 0.72 8.3 20.7 0.99 7.9 20.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF572 PF04502.13 EAU84543.2 - 0.89 9.1 20.0 1.4 8.5 20.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dicty_REP PF05086.12 EAU84543.2 - 6.2 4.7 10.7 10 4.0 10.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 2OG-FeII_Oxy_3 PF13640.6 EAU84544.1 - 1.7e-11 44.9 0.0 4.6e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peripla_BP_2 PF01497.18 EAU84544.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein 2OG-FeII_Oxy_3 PF13640.6 EAU84546.1 - 6e-09 36.7 0.0 1.3e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.20 EAU84547.2 - 1.7e-22 80.3 0.0 2.3e-21 76.6 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU84547.2 - 9.3e-17 62.4 1.2 2.9e-16 60.8 1.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU84547.2 - 5.9e-14 51.9 0.0 1.5e-11 44.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EAU84547.2 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 EAU84547.2 - 0.00029 20.6 0.1 0.00085 19.0 0.1 1.8 2 1 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 EAU84547.2 - 0.0023 17.8 0.0 1.5 8.6 0.0 3.3 4 0 0 4 4 4 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EAU84547.2 - 0.0023 17.8 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EAU84547.2 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Ndr PF03096.14 EAU84547.2 - 0.0027 16.5 0.0 0.0047 15.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 EAU84547.2 - 0.035 14.0 0.0 6.4 6.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3530 PF12048.8 EAU84547.2 - 0.067 12.6 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) Peptidase_S9 PF00326.21 EAU84547.2 - 0.077 12.5 0.0 9.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family SL4P PF17618.2 EAU84547.2 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein cwf21 PF08312.12 EAU84548.2 - 4e-15 55.7 11.3 4e-15 55.7 11.3 2.6 2 1 0 2 2 2 1 cwf21 domain 2OG-FeII_Oxy_3 PF13640.6 EAU84549.2 - 6.5e-10 39.8 0.0 1.4e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.6 EAU84550.1 - 8e-09 35.4 0.0 1.3e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU84550.1 - 1.1e-08 34.8 0.0 3.5e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DUF2089 PF09862.9 EAU84551.2 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Zn_clus PF00172.18 EAU84551.2 - 0.21 11.7 10.7 1.6 9.0 0.7 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM208_SND2 PF05620.11 EAU84553.1 - 1.3e-56 190.9 0.0 1.5e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Myb_DNA-binding PF00249.31 EAU84554.2 - 1.6e-42 143.4 9.7 4.1e-13 49.3 0.1 5.2 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU84554.2 - 8.1e-38 128.5 0.0 1.9e-10 40.8 0.0 5.2 3 2 2 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 EAU84554.2 - 1.6e-05 24.9 0.0 0.12 12.4 0.0 3.0 3 0 0 3 3 3 2 SLIDE Rap1_C PF11626.8 EAU84554.2 - 8e-05 22.7 0.3 0.29 11.3 0.0 3.0 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain ERp29 PF07749.12 EAU84554.2 - 0.043 14.7 0.4 9.6 7.2 0.0 3.4 3 1 1 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain MADF_DNA_bdg PF10545.9 EAU84554.2 - 0.12 12.7 1.4 50 4.3 0.0 4.0 4 1 0 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TAF8_C PF10406.9 EAU84555.2 - 2.1e-10 41.0 5.1 2.1e-10 41.0 5.1 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EAU84555.2 - 3.7e-06 26.8 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Flavokinase PF01687.17 EAU84556.2 - 2.4e-30 105.1 0.0 3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.19 EAU84557.2 - 8.5e-11 42.2 0.0 1.9e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.12 EAU84558.1 - 5.2e-28 96.8 5.7 5.7e-28 96.6 5.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.6 EAU84558.1 - 0.0037 17.0 0.0 0.0037 17.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Patched PF02460.18 EAU84560.2 - 4.6e-67 226.8 1.1 1.1e-34 119.7 0.0 3.2 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 EAU84560.2 - 6.7e-46 155.9 13.1 4.7e-25 88.2 0.1 3.6 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 EAU84560.2 - 4.8e-42 144.2 2.0 6.2e-38 130.7 0.1 2.2 1 1 1 2 2 2 2 Niemann-Pick C1 N terminus ACR_tran PF00873.19 EAU84560.2 - 6.2e-07 27.5 3.8 1.6e-06 26.1 1.6 2.0 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EAU84560.2 - 2.6 6.9 23.2 0.036 13.0 0.9 4.0 4 0 0 4 4 4 0 MMPL family Diphthamide_syn PF01866.17 EAU84561.2 - 2.7e-96 322.6 0.3 2.9e-58 197.7 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Pkinase PF00069.25 EAU84562.1 - 7.6e-66 222.2 0.0 1e-65 221.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84562.1 - 5.7e-29 101.2 0.0 8.1e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EAU84562.1 - 1.4e-21 76.9 2.7 4.2e-21 75.4 0.3 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EAU84562.1 - 1.1e-09 37.7 0.0 2.4e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EAU84562.1 - 7.5e-09 35.8 0.1 9.3e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 EAU84562.1 - 1.3e-07 31.2 0.1 5.8e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EAU84562.1 - 0.0016 18.1 0.8 0.41 10.2 0.1 2.8 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAU84562.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EAU84562.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAU84562.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Chorion_2 PF03964.15 EAU84562.1 - 6.8 7.6 7.0 24 5.8 6.5 2.2 1 1 0 1 1 1 0 Chorion family 2 Suc_Fer-like PF06999.12 EAU84563.2 - 8.3e-55 185.7 0.0 1e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like SIR2 PF02146.17 EAU84564.2 - 1.1e-33 116.6 0.0 1.2e-32 113.2 0.0 2.5 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EAU84564.2 - 0.0029 17.3 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.16 EAU84564.2 - 0.018 14.0 0.1 3.3 6.5 0.0 2.1 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Zn-ribbon_8 PF09723.10 EAU84564.2 - 0.17 12.0 1.4 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EAU84564.2 - 3.5 7.2 4.9 19 4.8 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain MRP-S26 PF14943.6 EAU84565.1 - 0.022 14.6 0.1 0.036 14.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Acyl-CoA_dh_1 PF00441.24 EAU84567.2 - 7.9e-29 100.8 0.6 1.2e-28 100.3 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAU84567.2 - 1.6e-20 73.1 0.0 4.5e-20 71.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EAU84567.2 - 9.2e-12 45.6 0.0 2.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EAU84567.2 - 1.1e-10 41.8 0.5 2.1e-10 41.0 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 EAU84568.2 - 2.2e-31 108.9 0.0 3.3e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU84568.2 - 7.9e-09 35.5 10.8 1.5e-08 34.6 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 EAU84568.2 - 0.0077 15.9 0.9 0.028 14.2 0.9 1.9 1 0 0 1 1 1 1 Integrin plexin domain IMD PF08397.11 EAU84570.2 - 1.2e-06 28.1 1.2 1.7e-06 27.6 1.2 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain BAR_3 PF16746.5 EAU84570.2 - 0.00065 19.5 2.2 0.00096 18.9 2.2 1.2 1 0 0 1 1 1 1 BAR domain of APPL family End3 PF12761.7 EAU84570.2 - 0.0062 16.7 0.6 0.015 15.5 0.6 1.6 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 OmpH PF03938.14 EAU84570.2 - 0.032 14.6 1.2 0.063 13.6 1.2 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 EAU84570.2 - 0.064 13.5 0.2 0.064 13.5 0.2 2.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 EAU84570.2 - 0.18 9.7 0.6 0.29 9.1 0.6 1.2 1 0 0 1 1 1 0 Prominin tRNA-synt_2 PF00152.20 EAU84571.2 - 1.4e-85 287.2 0.0 7.6e-42 143.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAU84571.2 - 5.3e-06 26.3 0.0 1.4e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain F-box-like PF12937.7 EAU84572.1 - 4.2e-05 23.4 0.5 9.5e-05 22.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU84572.1 - 0.0047 16.8 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box RNA_pol_Rpc34 PF05158.12 EAU84573.2 - 2.5e-72 244.1 0.0 1.1e-62 212.4 0.0 2.3 1 1 0 2 2 2 2 RNA polymerase Rpc34 subunit HxlR PF01638.17 EAU84573.2 - 0.14 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Macoilin PF09726.9 EAU84573.2 - 3.8 6.0 21.9 5.3 5.5 21.9 1.1 1 0 0 1 1 1 0 Macoilin family PA26 PF04636.13 EAU84573.2 - 5.6 5.8 6.3 8.2 5.2 6.3 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ACPS PF01648.20 EAU84574.2 - 4.8e-10 39.6 0.0 3.8e-09 36.7 0.0 2.4 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Herpes_UL82_83 PF05784.11 EAU84574.2 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus PfkB PF00294.24 EAU84575.2 - 0.012 15.0 0.7 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 pfkB family carbohydrate kinase CBFD_NFYB_HMF PF00808.23 EAU84576.2 - 2.1e-19 69.6 1.0 3.6e-19 68.8 1.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2458 PF10454.9 EAU84576.2 - 0.0074 16.0 0.9 0.01 15.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Histone PF00125.24 EAU84576.2 - 0.046 14.1 1.7 0.055 13.8 0.1 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 4HB_MCP_1 PF12729.7 EAU84576.2 - 0.62 9.6 4.6 0.76 9.3 4.3 1.3 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction LSM PF01423.22 EAU84577.2 - 6.6e-22 77.0 0.0 7.3e-22 76.8 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAU84577.2 - 0.0055 16.8 0.0 0.0068 16.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2423 PF10338.9 EAU84578.1 - 2.9e-15 56.2 6.6 3.6e-15 55.9 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 EAU84578.1 - 0.078 13.6 1.4 0.1 13.2 1.4 1.2 1 0 0 1 1 1 0 Learning-associated protein DUF4013 PF13197.6 EAU84579.2 - 0.0061 16.4 4.7 0.0061 16.4 4.7 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF4013) BOP1NT PF08145.12 EAU84580.2 - 1.7e-96 323.1 13.4 5.3e-95 318.2 13.4 2.2 1 1 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EAU84580.2 - 2.1e-21 75.8 6.6 0.00011 22.9 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84580.2 - 7.5e-06 26.2 0.1 2.8 8.3 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SDA1 PF05285.12 EAU84580.2 - 0.0026 17.3 16.8 0.0036 16.8 16.8 1.3 1 0 0 1 1 1 1 SDA1 DUF4502 PF14950.6 EAU84580.2 - 0.029 13.8 13.8 0.045 13.2 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) FCP1_C PF09309.10 EAU84580.2 - 0.19 11.6 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 FCP1, C-terminal RAB3GAP2_N PF14655.6 EAU84580.2 - 0.19 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1939 PF09154.10 EAU84580.2 - 0.48 10.6 2.0 0.92 9.7 0.0 2.6 4 0 0 4 4 2 0 Domain of unknown function (DUF1939) DUF5523 PF17661.1 EAU84580.2 - 0.54 9.9 18.8 0.81 9.3 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) SURF2 PF05477.11 EAU84580.2 - 1.9 8.1 16.2 3.3 7.3 16.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.12 EAU84580.2 - 9.9 4.2 25.9 13 3.8 25.9 1.1 1 0 0 1 1 1 0 Nop14-like family Actin PF00022.19 EAU84581.1 - 1.8e-115 385.8 0.0 2e-115 385.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EAU84581.1 - 4.9e-08 32.2 0.0 0.0021 17.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Sedlin_N PF04628.13 EAU84583.2 - 8.3e-13 48.6 0.0 5.5e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Rhomboid PF01694.22 EAU84584.2 - 5.2e-28 97.9 4.2 8.5e-28 97.2 4.2 1.3 1 0 0 1 1 1 1 Rhomboid family CLASP_N PF12348.8 EAU84585.2 - 4.6e-61 206.3 0.7 3e-55 187.3 0.0 3.1 3 1 1 4 4 4 2 CLASP N terminal HEAT PF02985.22 EAU84585.2 - 4.3e-06 26.5 2.0 9.2 6.8 0.1 5.5 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EAU84585.2 - 0.00029 21.3 0.5 2.3 8.8 0.0 4.3 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 EAU84585.2 - 0.018 15.1 2.6 2.2 8.3 0.1 3.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 AAA PF00004.29 EAU84587.1 - 5.6e-32 110.9 0.0 8.8e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAU84587.1 - 1.5e-08 35.0 0.1 3.2e-07 30.7 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU84587.1 - 2.4e-07 31.3 0.0 5.2e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EAU84587.1 - 1.7e-05 25.4 0.0 3.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EAU84587.1 - 3.5e-05 24.0 0.0 9.2e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EAU84587.1 - 0.00014 21.1 0.1 0.016 14.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EAU84587.1 - 0.00016 21.9 0.0 0.00046 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EAU84587.1 - 0.00021 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU84587.1 - 0.00025 20.9 0.1 0.00064 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAU84587.1 - 0.00029 20.5 0.8 0.16 11.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 EAU84587.1 - 0.00031 20.5 0.0 0.00086 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EAU84587.1 - 0.0004 20.4 0.0 0.3 10.9 0.1 2.3 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EAU84587.1 - 0.0012 18.9 0.2 0.0044 17.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EAU84587.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 EAU84587.1 - 0.002 17.9 0.0 0.0056 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU84587.1 - 0.0022 17.9 0.1 0.005 16.8 0.1 1.8 1 1 0 1 1 1 1 NACHT domain TsaE PF02367.17 EAU84587.1 - 0.0025 17.8 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EAU84587.1 - 0.0028 18.0 0.0 0.0083 16.5 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.6 EAU84587.1 - 0.0028 17.9 0.0 0.0071 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EAU84587.1 - 0.0029 17.3 0.0 0.0074 16.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EAU84587.1 - 0.0031 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 EAU84587.1 - 0.0037 17.0 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase IstB_IS21 PF01695.17 EAU84587.1 - 0.0045 16.7 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein KAP_NTPase PF07693.14 EAU84587.1 - 0.019 14.2 0.0 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 EAU84587.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAU84587.1 - 0.026 15.1 0.0 0.061 13.8 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_3 PF07726.11 EAU84587.1 - 0.028 14.3 0.0 0.084 12.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAU84587.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain CPT PF07931.12 EAU84587.1 - 0.038 13.8 0.0 0.066 13.0 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 EAU84587.1 - 0.042 14.3 0.0 0.074 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EAU84587.1 - 0.047 14.0 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EAU84587.1 - 0.051 12.9 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EAU84587.1 - 0.07 13.6 0.0 0.19 12.1 0.0 1.7 1 1 0 2 2 1 0 AAA domain PhoH PF02562.16 EAU84587.1 - 0.073 12.5 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 EAU84587.1 - 0.085 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EAU84587.1 - 0.089 12.1 0.3 1.6 8.0 0.0 2.4 2 1 1 3 3 3 0 KaiC PduV-EutP PF10662.9 EAU84587.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 EAU84587.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.6 EAU84588.2 - 0.13 12.5 0.0 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 PPR repeat family LSM PF01423.22 EAU84589.1 - 1.4e-20 72.7 0.0 1.5e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EAU84589.1 - 0.055 13.1 0.1 0.081 12.6 0.1 1.4 1 1 0 1 1 1 0 Hfq protein MDM10 PF12519.8 EAU84591.1 - 1.2e-96 324.4 0.1 2.1e-85 287.4 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EAU84591.1 - 0.0028 17.2 0.2 4.2 6.8 0.0 3.9 4 1 0 4 4 4 2 Eukaryotic porin Pkinase PF00069.25 EAU84593.2 - 6.4e-34 117.5 0.0 4.2e-33 114.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84593.2 - 2e-31 109.2 0.0 3.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAU84593.2 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkr1 PF08636.10 EAU84594.1 - 1.9e-20 72.7 2.0 2.5e-20 72.4 2.0 1.0 1 0 0 1 1 1 1 ER protein Pkr1 Sld5 PF05916.11 EAU84595.1 - 1.4e-06 28.7 0.0 2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF1860 PF08949.10 EAU84595.1 - 0.11 12.2 0.2 0.15 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) EMP24_GP25L PF01105.24 EAU84599.1 - 4e-40 137.7 0.0 4.6e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 EAU84599.1 - 0.019 15.4 0.3 0.032 14.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) Acetyltransf_7 PF13508.7 EAU84600.2 - 0.00044 20.6 0.0 0.00099 19.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU84600.2 - 0.023 14.9 0.0 0.08 13.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EAU84600.2 - 0.14 12.2 0.3 0.46 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain BAR_2 PF10455.9 EAU84601.1 - 4.5e-48 163.8 0.2 1.3e-47 162.3 0.2 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EAU84601.1 - 1.6e-16 60.7 0.2 4.6e-13 49.4 0.1 2.1 2 0 0 2 2 2 2 BAR domain p450 PF00067.22 EAU84602.2 - 8.6e-67 225.9 0.0 2.6e-66 224.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Beta-APP PF03494.13 EAU84602.2 - 0.017 15.0 0.1 0.092 12.6 0.0 2.3 2 1 0 2 2 2 0 Beta-amyloid peptide (beta-APP) p450 PF00067.22 EAU84603.2 - 1.3e-64 218.7 0.0 4.9e-64 216.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PP2C PF00481.21 EAU84604.2 - 0.00022 20.9 0.1 0.017 14.7 0.0 2.7 3 0 0 3 3 3 1 Protein phosphatase 2C SpoIIE PF07228.12 EAU84604.2 - 0.0011 18.9 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EAU84604.2 - 0.017 14.8 0.4 0.095 12.3 0.0 2.3 2 1 0 2 2 2 0 Protein phosphatase 2C tRNA-synt_1 PF00133.22 EAU84605.1 - 1.1e-219 730.7 0.0 1.1e-218 727.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAU84605.1 - 2.4e-34 118.5 0.1 5.2e-34 117.4 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAU84605.1 - 1.4e-14 53.7 1.7 2.2e-07 30.0 0.0 4.7 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EAU84605.1 - 1.7e-12 47.2 0.1 2.6e-08 33.6 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EAU84605.1 - 0.013 14.9 0.0 0.42 9.9 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain YqfQ PF14181.6 EAU84605.1 - 1.9 8.7 11.4 3.6 7.8 11.4 1.4 1 0 0 1 1 1 0 YqfQ-like protein dUTPase PF00692.19 EAU84606.1 - 3.3e-43 146.4 0.0 4e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase Glu-tRNAGln PF02686.15 EAU84607.1 - 0.0062 16.8 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit MRP-S34 PF16053.5 EAU84608.1 - 2.2e-11 43.5 1.1 2.9e-11 43.1 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 DUF4531 PF15041.6 EAU84608.1 - 0.15 12.1 3.6 3.8 7.6 0.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4531) Peptidase_M43 PF05572.13 EAU84609.2 - 1e-17 64.5 0.0 1.5e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU84609.2 - 4.5e-06 27.0 0.1 5.9e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU84609.2 - 8.6e-05 23.0 0.0 0.00013 22.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU84609.2 - 0.0006 19.5 0.0 0.00084 19.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EAU84609.2 - 0.0057 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EAU84609.2 - 0.0063 15.5 1.1 0.01 14.8 1.1 1.2 1 0 0 1 1 1 1 Peptidase M66 MBOAT PF03062.19 EAU84610.2 - 8.3e-55 186.5 24.7 8.3e-55 186.5 24.7 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ACBP PF00887.19 EAU84611.2 - 2.3e-19 69.4 0.0 3.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein ADH_N PF08240.12 EAU84612.1 - 4.2e-25 87.8 1.2 8.4e-25 86.8 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU84612.1 - 6.5e-20 71.4 0.1 1.3e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EAU84612.1 - 0.00015 21.1 0.1 0.00028 20.2 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EAU84612.1 - 0.0009 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 EAU84612.1 - 0.017 14.5 0.5 0.14 11.5 0.5 2.1 2 0 0 2 2 2 0 ThiF family COX15-CtaA PF02628.15 EAU84615.2 - 2.5e-108 362.0 9.5 3.1e-108 361.7 9.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BolA PF01722.18 EAU84616.1 - 4.2e-13 49.4 0.0 1.4e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein TerB_C PF15615.6 EAU84616.1 - 0.2 12.0 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 TerB-C domain PQQ PF01011.21 EAU84617.2 - 2.9e-05 23.8 0.7 0.048 13.6 0.0 4.3 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_2 PF13360.6 EAU84617.2 - 0.00034 20.3 0.2 0.32 10.5 0.0 3.4 3 0 0 3 3 3 1 PQQ-like domain PQQ_3 PF13570.6 EAU84617.2 - 0.0079 16.7 14.4 0.55 10.8 0.1 5.8 6 1 0 6 6 6 2 PQQ-like domain DIM PF08194.12 EAU84617.2 - 0.26 11.5 0.9 1.7 8.9 0.4 2.3 2 0 0 2 2 2 0 DIM protein Methyltransf_16 PF10294.9 EAU84618.2 - 6.7e-48 162.7 0.0 1e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EAU84618.2 - 0.00034 20.5 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAU84618.2 - 0.0043 16.5 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EAU84618.2 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AMPK1_CBM PF16561.5 EAU84619.1 - 2.4e-17 62.9 0.5 3.8e-17 62.3 0.5 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase BTB PF00651.31 EAU84620.1 - 2.4e-05 24.5 0.0 6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Haem_degrading PF03928.14 EAU84624.2 - 1.3e-08 34.9 0.0 3.2e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Haem-degrading FH2 PF02181.23 EAU84626.2 - 3.3e-89 299.6 0.0 3.3e-89 299.6 0.0 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EAU84626.2 - 5.1e-26 91.4 0.5 3.2e-20 72.5 0.4 2.5 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EAU84626.2 - 1.1e-20 74.1 0.1 1.1e-20 74.1 0.1 2.5 2 1 1 3 3 3 1 Diaphanous FH3 Domain Mito_fiss_reg PF05308.11 EAU84626.2 - 0.0026 17.9 13.6 0.0026 17.9 13.6 7.0 3 1 1 5 5 4 1 Mitochondrial fission regulator Nmad5 PF18757.1 EAU84626.2 - 0.007 16.6 3.8 0.25 11.5 0.1 3.4 3 0 0 3 3 3 1 Nucleotide modification associated domain 5 SOGA PF11365.8 EAU84626.2 - 0.015 16.4 17.8 1.2 10.3 5.1 4.2 2 1 1 3 3 3 0 Protein SOGA XLF PF09302.11 EAU84626.2 - 0.048 13.8 4.3 0.03 14.5 0.8 2.5 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Spc7 PF08317.11 EAU84626.2 - 0.049 12.5 27.2 0.014 14.3 4.9 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein SKA2 PF16740.5 EAU84626.2 - 0.071 12.9 4.2 0.47 10.3 0.0 3.8 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Lzipper-MIP1 PF14389.6 EAU84626.2 - 0.079 13.3 13.5 0.031 14.6 3.6 3.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.18 EAU84626.2 - 0.096 13.0 12.5 1.4 9.3 2.8 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF4407 PF14362.6 EAU84626.2 - 0.17 11.2 10.7 26 4.0 10.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AATF-Che1 PF13339.6 EAU84626.2 - 0.33 11.6 15.6 0.75 10.5 4.4 5.6 5 1 0 5 5 5 0 Apoptosis antagonizing transcription factor SHE3 PF17078.5 EAU84626.2 - 0.6 9.8 20.5 4 7.1 4.6 3.9 2 2 1 3 3 3 0 SWI5-dependent HO expression protein 3 Seryl_tRNA_N PF02403.22 EAU84626.2 - 0.79 10.0 17.5 0.48 10.7 4.8 4.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.12 EAU84626.2 - 1.2 9.9 16.7 0.75 10.5 0.1 5.6 4 0 0 4 4 4 0 SlyX KASH_CCD PF14662.6 EAU84626.2 - 1.2 9.0 26.9 0.9 9.3 7.4 3.5 2 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DivIVA PF05103.13 EAU84626.2 - 1.9 8.6 12.1 3.9 7.6 4.6 3.1 3 0 0 3 3 2 0 DivIVA protein JIP_LZII PF16471.5 EAU84626.2 - 2.1 8.6 8.6 1.8 8.8 3.4 3.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FAM76 PF16046.5 EAU84626.2 - 2.3 7.5 10.4 9.5 5.5 10.1 2.3 1 1 0 1 1 1 0 FAM76 protein Tup_N PF08581.10 EAU84626.2 - 2.3 8.6 10.2 4.5 7.6 0.8 3.7 4 0 0 4 4 2 0 Tup N-terminal Atg14 PF10186.9 EAU84626.2 - 2.5 7.1 16.5 6.3 5.8 8.9 3.1 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF713 PF05218.14 EAU84626.2 - 5.5 6.7 6.4 3 7.6 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF713) CENP-F_leu_zip PF10473.9 EAU84626.2 - 7.8 6.5 22.2 0.59 10.2 1.3 3.2 3 0 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 EAU84626.2 - 8.3 6.0 19.0 9.7 5.8 12.1 3.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 EAU84626.2 - 9.1 6.8 32.1 0.12 13.0 5.1 3.8 2 1 1 3 3 3 0 Apg6 coiled-coil region Tubulin PF00091.25 EAU84627.1 - 2.9e-66 223.4 0.0 3.9e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAU84627.1 - 2.2e-47 160.3 0.0 3.4e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAU84627.1 - 0.00018 21.2 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 EAU84627.1 - 0.088 12.7 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) HAD_2 PF13419.6 EAU84628.1 - 6.5e-17 62.2 0.0 8.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU84628.1 - 3.3e-10 40.6 0.0 4e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU84628.1 - 4.6e-09 36.2 0.0 8.9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EAU84628.1 - 0.085 13.3 0.0 0.26 11.7 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sec15 PF04091.12 EAU84629.2 - 4.9e-98 328.4 0.4 1.2e-97 327.1 0.4 1.7 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 EAU84629.2 - 4.5e-08 33.3 0.6 4.5e-08 33.3 0.6 3.4 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 EAU84629.2 - 2.3e-05 24.3 2.1 3.1e-05 23.9 0.3 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps51 PF08700.11 EAU84629.2 - 0.00021 21.3 0.5 0.00021 21.3 0.5 3.4 3 0 0 3 3 3 1 Vps51/Vps67 DUF1351 PF07083.11 EAU84629.2 - 0.0084 15.9 0.8 0.025 14.4 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) COG2 PF06148.11 EAU84629.2 - 0.011 15.8 5.2 0.027 14.6 1.4 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prominin PF05478.11 EAU84629.2 - 0.021 12.8 5.0 0.15 10.0 0.1 2.4 2 0 0 2 2 2 0 Prominin HrpB7 PF09486.10 EAU84629.2 - 0.48 10.8 0.0 0.48 10.8 0.0 3.3 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) RAC_head PF16717.5 EAU84629.2 - 0.63 11.1 2.7 1.2 10.1 0.1 2.9 3 0 0 3 3 3 0 Ribosome-associated complex head domain Baculo_PEP_C PF04513.12 EAU84629.2 - 2.1 8.4 11.8 22 5.1 0.3 4.6 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Arf PF00025.21 EAU84630.1 - 2.1e-79 265.0 0.1 2.4e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAU84630.1 - 1.5e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAU84630.1 - 3.4e-14 52.7 0.0 4.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EAU84630.1 - 4.3e-13 49.2 1.0 4.2e-09 36.0 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EAU84630.1 - 8.1e-13 48.3 0.0 9.2e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAU84630.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU84630.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EAU84630.1 - 0.0068 15.7 0.6 0.019 14.3 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Chromate_transp PF02417.15 EAU84631.2 - 3.1e-58 196.4 35.5 1.6e-34 119.3 13.5 2.4 3 0 0 3 3 3 2 Chromate transporter DUF2076 PF09849.9 EAU84632.2 - 0.2 11.7 6.0 0.27 11.3 6.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3245 PF11595.8 EAU84634.2 - 4.7e-06 27.2 1.8 4.7e-06 27.2 1.8 3.7 2 2 1 3 3 3 1 Protein of unknown function (DUF3245) Soyouz_module PF14313.6 EAU84634.2 - 0.025 14.4 0.2 0.057 13.2 0.2 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) NOP19 PF10863.8 EAU84634.2 - 0.035 13.9 0.3 0.035 13.9 0.3 2.9 4 0 0 4 4 4 0 Nucleolar protein 19 G-patch_2 PF12656.7 EAU84634.2 - 0.54 10.4 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 G-patch domain SPT6_acidic PF14632.6 EAU84634.2 - 9.4 6.9 13.3 8 7.1 3.5 2.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 SIP1 PF04938.12 EAU84635.2 - 4e-23 82.3 0.0 8.1e-23 81.3 0.0 1.5 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Acetyltransf_10 PF13673.7 EAU84636.1 - 9.5e-08 32.0 0.0 1.5e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU84636.1 - 1.7e-07 31.5 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU84636.1 - 2.2e-05 24.7 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EAU84636.1 - 0.00073 19.6 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU84636.1 - 0.016 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Integrin_alpha2 PF08441.12 EAU84636.1 - 0.21 10.4 0.1 0.29 10.0 0.1 1.1 1 0 0 1 1 1 0 Integrin alpha GPI-anchored PF10342.9 EAU84637.1 - 4.2e-08 33.8 0.1 9.6e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box-like PF12937.7 EAU84638.1 - 0.0028 17.5 0.4 0.023 14.6 0.0 2.6 2 0 0 2 2 2 1 F-box-like GPI-anchored PF10342.9 EAU84639.2 - 1.4e-10 41.8 0.4 2.9e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MSP1_C PF07462.11 EAU84639.2 - 1.4 7.6 4.1 1.8 7.1 4.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Chromate_transp PF02417.15 EAU84640.1 - 7.9e-65 217.8 32.9 1.3e-38 132.6 10.7 2.7 2 1 1 3 3 3 2 Chromate transporter QRPTase_C PF01729.19 EAU84641.2 - 2.4e-48 164.1 0.0 3e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EAU84641.2 - 3.1e-20 72.0 0.0 9.9e-20 70.4 0.0 1.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain KDGP_aldolase PF07071.11 EAU84641.2 - 0.0027 17.5 0.0 0.05 13.4 0.0 2.2 2 0 0 2 2 2 1 KDGP aldolase HTH_51 PF18558.1 EAU84641.2 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain SBD_N PF07005.11 EAU84641.2 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Sugar-binding N-terminal domain ECH_1 PF00378.20 EAU84645.2 - 5.3e-53 179.9 0.0 6.6e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAU84645.2 - 2e-22 80.1 0.7 4.1e-19 69.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Sec10 PF07393.11 EAU84646.2 - 5.4e-218 725.9 0.1 8.9e-218 725.2 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 BAR_3_WASP_bdg PF10456.9 EAU84646.2 - 0.062 12.7 0.5 0.25 10.8 0.1 2.2 3 0 0 3 3 3 0 WASP-binding domain of Sorting nexin protein Peptidase_S46 PF10459.9 EAU84646.2 - 0.11 11.1 2.7 0.22 10.1 2.6 1.4 1 1 0 1 1 1 0 Peptidase S46 CHIP_TPR_N PF18391.1 EAU84646.2 - 0.58 11.0 3.9 8.3 7.3 0.4 2.9 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain RIX1 PF08167.12 EAU84647.2 - 2.3e-31 109.0 3.0 2.3e-31 109.0 3.0 2.7 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 EAU84648.1 - 0.034 15.0 0.8 10 7.2 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU84648.1 - 0.079 13.1 0.2 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_I_TF PF04090.12 EAU84648.1 - 0.18 11.3 0.2 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor DUF5102 PF17104.5 EAU84649.2 - 1.7e-73 248.2 0.3 2e-73 247.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Filament_head PF04732.14 EAU84652.2 - 6.4 7.7 11.7 12 6.9 2.6 3.0 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region PBP PF01161.20 EAU84653.2 - 8e-06 26.2 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CarboxypepD_reg PF13620.6 EAU84653.2 - 0.022 15.0 0.5 0.059 13.6 0.5 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain RRM_1 PF00076.22 EAU84654.1 - 1.1e-18 66.8 1.9 1.5e-18 66.4 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAU84654.1 - 1.8e-08 34.0 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU84654.1 - 0.086 12.7 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif DEAD PF00270.29 EAU84657.1 - 2.5e-43 147.8 0.1 4.6e-43 147.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU84657.1 - 7.3e-32 110.0 0.1 2.8e-31 108.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EAU84657.1 - 0.00039 20.8 0.1 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EAU84657.1 - 0.00083 19.4 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAU84657.1 - 0.043 13.5 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU84657.1 - 0.07 13.4 0.5 0.36 11.1 0.5 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 EAU84657.1 - 0.13 11.6 0.0 0.4 9.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.21 EAU84657.1 - 0.14 11.6 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3449 PF11931.8 EAU84658.2 - 3.7e-69 232.2 0.4 3.7e-69 232.2 0.4 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EAU84658.2 - 5.4e-24 84.5 4.7 5.4e-24 84.5 4.7 2.8 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EAU84658.2 - 3e-06 27.0 0.5 7e-06 25.8 0.5 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EAU84658.2 - 5.7e-06 26.5 5.1 2.9e-05 24.3 0.5 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAU84658.2 - 7e-06 26.2 2.4 1.3e-05 25.3 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding CDC27 PF09507.10 EAU84658.2 - 0.1 12.0 5.1 0.16 11.3 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2_2 PF12756.7 EAU84658.2 - 0.14 12.5 1.5 0.39 11.1 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Syja_N PF02383.18 EAU84659.2 - 6.9e-74 249.0 0.0 9.8e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Erv26 PF04148.13 EAU84659.2 - 1.5e-67 227.4 7.8 2.4e-67 226.8 7.8 1.3 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Exo_endo_phos PF03372.23 EAU84659.2 - 4.4e-14 52.6 0.2 8.8e-14 51.6 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Snf7 PF03357.21 EAU84660.2 - 1.4e-09 37.8 14.5 1.9e-09 37.3 14.5 1.3 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 EAU84660.2 - 0.0056 16.3 0.8 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase hGDE_central PF14702.6 EAU84660.2 - 0.057 13.1 2.3 0.069 12.8 2.3 1.2 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme NOG1_N PF17835.1 EAU84660.2 - 1.1 9.2 6.5 0.76 9.7 0.2 2.9 1 1 1 3 3 3 0 NOG1 N-terminal helical domain Abhydrolase_1 PF00561.20 EAU84662.1 - 2.7e-39 135.4 0.0 6.1e-39 134.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EAU84662.1 - 0.015 14.9 0.2 0.027 14.1 0.2 1.4 1 0 0 1 1 1 0 Putative esterase Snf7 PF03357.21 EAU84663.1 - 7.2e-46 155.9 14.8 8.8e-46 155.7 14.8 1.0 1 0 0 1 1 1 1 Snf7 FlxA PF14282.6 EAU84663.1 - 0.0066 16.4 16.0 0.049 13.6 9.8 2.3 1 1 1 2 2 2 1 FlxA-like protein NPV_P10 PF05531.12 EAU84663.1 - 0.028 14.9 1.7 0.24 11.9 0.2 2.6 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.11 EAU84663.1 - 0.033 14.4 2.5 0.054 13.7 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) TssC PF17541.2 EAU84663.1 - 0.07 11.9 3.5 0.086 11.7 3.5 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB TRPM_tetra PF16519.5 EAU84663.1 - 0.077 13.1 2.0 0.2 11.8 1.1 2.1 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Prefoldin_2 PF01920.20 EAU84663.1 - 0.27 11.2 14.6 6.7 6.7 0.0 3.6 2 1 0 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 EAU84663.1 - 0.41 10.7 5.4 0.38 10.8 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CPSase_L_D3 PF02787.19 EAU84663.1 - 0.46 10.8 4.2 0.41 11.0 2.5 1.8 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Prominin PF05478.11 EAU84663.1 - 0.53 8.2 6.2 0.61 8.0 6.2 1.1 1 0 0 1 1 1 0 Prominin GPS2_interact PF15784.5 EAU84663.1 - 0.91 10.0 7.2 0.19 12.2 1.7 2.4 1 1 2 3 3 3 0 G-protein pathway suppressor 2-interacting domain DUF5344 PF17279.2 EAU84663.1 - 1.1 9.9 11.6 0.91 10.1 6.0 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5344) FlaC_arch PF05377.11 EAU84663.1 - 1.5 9.3 10.7 3.3 8.2 0.0 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) MerR-DNA-bind PF09278.11 EAU84663.1 - 3.3 8.3 6.6 3.5 8.2 0.0 3.3 2 2 1 3 3 3 0 MerR, DNA binding FapA PF03961.13 EAU84663.1 - 4.5 5.8 12.6 2.3 6.7 3.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PepSY_TM_like_2 PF16357.5 EAU84663.1 - 6.3 6.7 5.1 32 4.4 5.1 1.9 1 1 0 1 1 1 0 Putative PepSY_TM-like TMCCDC2 PF15844.5 EAU84664.2 - 0.026 14.4 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 BTB PF00651.31 EAU84666.2 - 2.2e-06 27.9 0.0 8.1e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Vps52 PF04129.12 EAU84667.2 - 2.2e-59 201.6 2.9 1.2e-39 136.5 0.1 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 EAU84667.2 - 5.6e-06 25.1 0.6 0.00026 19.5 0.6 2.6 2 1 0 2 2 2 2 Exocyst complex component Sec3 DUF4201 PF13870.6 EAU84667.2 - 0.016 14.9 1.1 0.061 13.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) COG2 PF06148.11 EAU84667.2 - 0.15 12.2 2.3 0.65 10.1 0.3 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PhaP_Bmeg PF09602.10 EAU84667.2 - 3.4 7.6 6.6 1.4 8.9 0.4 2.9 3 1 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) THOC7 PF05615.13 EAU84668.2 - 2.6e-34 118.3 3.5 2.6e-34 118.3 3.5 2.2 1 1 1 2 2 2 2 Tho complex subunit 7 DUF4515 PF14988.6 EAU84668.2 - 0.013 15.4 9.8 0.021 14.7 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF87 PF01935.17 EAU84668.2 - 0.015 15.4 0.4 0.067 13.3 0.3 2.0 1 1 0 1 1 1 0 Helicase HerA, central domain PIN_8 PF18476.1 EAU84668.2 - 0.024 14.5 4.0 0.045 13.6 4.0 1.3 1 0 0 1 1 1 0 PIN like domain Biopterin_H PF00351.21 EAU84668.2 - 0.15 11.0 0.9 0.41 9.6 0.8 1.6 1 1 1 2 2 2 0 Biopterin-dependent aromatic amino acid hydroxylase FlaC_arch PF05377.11 EAU84668.2 - 0.16 12.4 5.1 1.4 9.4 0.1 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EAU84668.2 - 0.19 11.7 4.8 0.74 9.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EAU84668.2 - 0.24 11.4 13.0 1.1 9.3 0.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EAU84668.2 - 0.41 10.0 5.8 0.61 9.4 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 EAU84668.2 - 0.51 9.6 11.0 1.2 8.4 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NYD-SP28_assoc PF14775.6 EAU84668.2 - 0.68 10.1 4.2 6.5 7.0 2.1 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cortex-I_coil PF09304.10 EAU84668.2 - 1.7 8.9 11.1 1.8 8.8 0.7 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil Uds1 PF15456.6 EAU84668.2 - 6.1 7.0 12.8 0.12 12.6 5.4 1.8 2 1 0 2 2 2 0 Up-regulated During Septation Golgin_A5 PF09787.9 EAU84668.2 - 6.4 6.1 18.5 0.062 12.8 10.8 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Vps5 PF09325.10 EAU84670.1 - 5.1e-15 55.7 1.7 7.5e-15 55.1 1.7 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EAU84670.1 - 1.9e-10 40.7 0.0 4.2e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Glyco_hydro_17 PF00332.18 EAU84671.2 - 2.6e-10 40.4 0.0 1.2e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 GTP_cyclohydro2 PF00925.20 EAU84672.1 - 4.2e-59 198.8 0.0 6.5e-59 198.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Jnk-SapK_ap_N PF09744.9 EAU84673.1 - 0.0043 17.3 6.7 0.0094 16.2 6.7 1.6 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 EAU84673.1 - 0.032 14.5 11.5 0.055 13.7 0.7 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FapA PF03961.13 EAU84673.1 - 0.13 10.8 0.7 0.23 10.0 0.6 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A ZapB PF06005.12 EAU84673.1 - 0.36 11.3 14.0 2.1 8.8 4.6 3.3 1 1 1 2 2 2 0 Cell division protein ZapB Cnn_1N PF07989.11 EAU84673.1 - 0.39 10.9 3.2 0.49 10.6 0.4 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4201 PF13870.6 EAU84673.1 - 1.1 9.0 8.4 3.9 7.2 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) KASH_CCD PF14662.6 EAU84673.1 - 1.2 8.9 7.6 3.9 7.3 7.6 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Occludin_ELL PF07303.13 EAU84673.1 - 2.1 9.1 7.0 1.2 9.9 0.9 2.5 1 1 1 2 2 2 0 Occludin homology domain Syntaxin_2 PF14523.6 EAU84673.1 - 2.7 8.4 10.1 0.33 11.3 4.4 2.4 2 1 0 2 2 2 0 Syntaxin-like protein Leu_zip PF15294.6 EAU84673.1 - 4 6.9 9.0 0.16 11.4 3.0 1.6 2 0 0 2 2 2 0 Leucine zipper TACC_C PF05010.14 EAU84673.1 - 4.5 7.0 8.8 0.39 10.5 3.8 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YabA PF06156.13 EAU84673.1 - 8.7 7.0 9.0 23 5.7 4.8 3.0 2 1 1 3 3 3 0 Initiation control protein YabA TFR_dimer PF04253.15 EAU84674.2 - 1e-19 70.8 0.2 5.1e-18 65.3 0.0 2.8 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EAU84674.2 - 3.3e-09 36.7 0.0 1.3e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAU84674.2 - 1.4e-07 31.4 0.0 3.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF282 PF03380.14 EAU84675.1 - 0.08 12.9 0.3 0.34 10.9 0.3 2.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 CDP-OH_P_tran_2 PF08009.11 EAU84675.1 - 0.18 11.7 2.3 0.29 11.1 2.3 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 JAB PF01398.21 EAU84677.1 - 1.3e-33 115.4 0.1 2.3e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EAU84677.1 - 9.8e-14 51.7 1.0 1.7e-13 51.0 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EAU84677.1 - 3.9e-07 29.9 0.0 6.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain AAA_25 PF13481.6 EAU84677.1 - 0.046 13.3 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF5624 PF18538.1 EAU84677.1 - 0.054 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) UPF0172 PF03665.13 EAU84677.1 - 0.056 13.5 0.4 0.11 12.5 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.20 EAU84678.1 - 1.1e-15 57.5 0.3 1.7e-15 57.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 Cro PF09048.10 EAU84678.1 - 0.16 12.0 0.0 0.96 9.5 0.0 2.1 2 0 0 2 2 2 0 Cro UIM PF02809.20 EAU84680.2 - 0.0012 18.7 13.2 0.2 11.7 4.5 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Flavi_propep PF01570.17 EAU84680.2 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Flavivirus polyprotein propeptide RAP80_UIM PF18282.1 EAU84680.2 - 0.28 11.0 6.2 0.61 9.9 6.2 1.5 1 0 0 1 1 1 0 RAP80 N-terminal ubiquitin interaction motif Ribonuc_red_sm PF00268.21 EAU84681.2 - 3.3e-116 387.6 0.3 4e-116 387.4 0.3 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EAU84681.2 - 0.066 14.1 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Ribonuc_red_sm PF00268.21 EAU84682.1 - 1.8e-124 414.8 1.8 2.2e-124 414.5 1.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EAU84682.1 - 0.11 13.3 0.0 0.36 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Alg6_Alg8 PF03155.15 EAU84684.2 - 2.6e-128 429.0 24.3 3e-128 428.9 24.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family KCH PF16944.5 EAU84687.1 - 1.8e-87 293.3 15.2 2.2e-87 293.0 15.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF2593 PF10767.9 EAU84687.1 - 8.3 6.5 7.8 1.5 8.9 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2593) V-SNARE_C PF12352.8 EAU84688.2 - 1e-16 60.9 6.0 1.9e-16 60.1 5.2 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EAU84688.2 - 1e-07 32.2 8.1 2.4e-06 27.8 1.3 3.6 2 2 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 EAU84688.2 - 0.00023 21.0 0.4 0.00067 19.5 0.4 1.8 1 0 0 1 1 1 1 Sec20 TBCC_N PF16752.5 EAU84688.2 - 0.005 17.3 3.8 1.8 9.0 1.0 2.4 2 1 0 2 2 2 2 Tubulin-specific chaperone C N-terminal domain Phospholamban PF04272.14 EAU84688.2 - 0.0058 16.1 4.4 0.015 14.7 0.4 2.3 2 0 0 2 2 2 1 Phospholamban Sec8_exocyst PF04048.14 EAU84688.2 - 0.016 15.1 1.0 3.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain YqjK PF13997.6 EAU84688.2 - 0.063 13.5 3.2 0.079 13.2 0.9 2.3 1 1 1 2 2 2 0 YqjK-like protein DUF3619 PF12279.8 EAU84688.2 - 0.11 12.8 6.5 1.5 9.2 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) SNARE PF05739.19 EAU84688.2 - 0.69 10.0 3.4 0.33 11.0 0.7 1.9 2 0 0 2 2 2 0 SNARE domain EMC3_TMCO1 PF01956.16 EAU84689.2 - 3.5e-36 124.5 12.7 6.7e-33 113.8 8.1 2.3 2 1 0 2 2 2 2 Integral membrane protein EMC3/TMCO1-like EF-hand_1 PF00036.32 EAU84690.2 - 1.1e-24 84.1 13.0 4e-08 32.2 0.1 5.1 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EAU84690.2 - 1.8e-23 82.8 9.6 2.1e-15 56.9 2.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAU84690.2 - 1.9e-21 74.1 8.4 3.3e-06 26.6 0.2 5.3 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EAU84690.2 - 1.7e-13 50.2 9.4 1.2e-06 28.3 0.4 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EAU84690.2 - 5.3e-13 47.8 12.4 0.00051 19.4 0.4 4.6 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.9 EAU84690.2 - 6.8e-08 32.8 0.9 1.2e-05 25.6 0.1 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAU84690.2 - 7.2e-07 29.1 6.1 0.053 13.5 0.1 4.0 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EAU84690.2 - 9e-07 29.1 0.5 0.0082 16.4 0.1 3.0 3 1 1 4 4 4 2 EF-hand domain Pan3_PK PF18101.1 EAU84690.2 - 0.033 14.2 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain EF-hand_3 PF09069.11 EAU84690.2 - 0.06 13.8 0.2 0.3 11.5 0.1 2.1 2 0 0 2 2 2 0 EF-hand EF-hand_2 PF09068.11 EAU84690.2 - 0.097 12.8 0.1 16 5.7 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_14 PF17959.1 EAU84690.2 - 0.11 12.9 3.2 3 8.2 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain ATP-synt PF00231.19 EAU84690.2 - 0.13 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase p25-alpha PF05517.12 EAU84690.2 - 0.14 12.3 4.4 6.4 6.9 1.0 2.5 1 1 0 2 2 2 0 p25-alpha EF-hand_11 PF08976.11 EAU84690.2 - 0.15 12.9 0.4 2.8 8.9 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 EAU84690.2 - 0.16 11.9 1.7 6.1 6.8 0.2 3.4 4 0 0 4 4 4 0 EF hand Caleosin PF05042.13 EAU84690.2 - 0.23 11.4 6.1 5.6 6.9 0.2 3.4 1 1 1 3 3 3 0 Caleosin related protein ANAPC4_WD40 PF12894.7 EAU84692.1 - 0.0039 17.4 0.0 0.29 11.5 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU84692.1 - 0.011 16.6 0.0 1.5 9.8 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1513 PF07433.11 EAU84692.1 - 0.065 12.3 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DASH_Dad4 PF08650.10 EAU84693.1 - 2e-28 98.1 0.8 2.2e-28 98.0 0.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 RNaseH_like PF04308.12 EAU84693.1 - 0.055 13.4 0.2 0.057 13.3 0.2 1.1 1 0 0 1 1 1 0 Ribonuclease H-like Peptidase_M18 PF02127.15 EAU84696.1 - 1.2e-163 544.9 0.0 1.4e-163 544.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EAU84696.1 - 2e-05 23.8 0.0 0.00084 18.4 0.1 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase WD40 PF00400.32 EAU84697.2 - 2.6e-55 183.1 25.9 5e-07 30.3 0.1 12.1 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84697.2 - 2.3e-24 85.5 3.2 0.00059 20.1 0.0 9.5 4 3 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EAU84697.2 - 2.6e-19 69.5 0.6 4.4e-19 68.8 0.6 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EAU84697.2 - 1.1e-06 27.8 4.0 2 7.3 0.0 5.8 3 2 3 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EAU84697.2 - 2.9e-06 26.2 3.8 0.0037 16.0 0.1 4.2 5 0 0 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EAU84697.2 - 9.2e-06 25.2 0.0 0.56 9.5 0.1 3.9 5 0 0 5 5 5 2 WD40-like domain Utp21 PF04192.12 EAU84697.2 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Utp8 PF10395.9 EAU84697.2 - 0.015 13.8 0.1 0.99 7.8 0.0 2.9 2 1 0 2 2 2 0 Utp8 family Coatomer_WDAD PF04053.14 EAU84697.2 - 0.018 14.1 0.0 0.58 9.1 0.0 2.8 2 1 1 3 3 3 0 Coatomer WD associated region Nucleoporin_N PF08801.11 EAU84697.2 - 0.024 13.4 0.5 6.4 5.4 0.0 4.2 4 2 1 5 5 5 0 Nup133 N terminal like ELYS-bb PF16687.5 EAU84697.2 - 0.03 12.9 0.0 0.26 9.8 0.0 2.3 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin PALB2_WD40 PF16756.5 EAU84697.2 - 0.13 11.1 2.3 12 4.7 0.0 3.5 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DPBB_1 PF03330.18 EAU84698.1 - 2.7e-07 30.8 0.0 4.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Fungal_trans PF04082.18 EAU84699.2 - 5.6e-23 81.3 0.1 1.3e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sdh_cyt PF01127.22 EAU84699.2 - 0.15 12.1 0.4 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CrgA PF06781.12 EAU84701.1 - 0.12 12.4 1.2 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 Cell division protein CrgA SNARE_assoc PF09335.11 EAU84702.1 - 4.1e-16 59.5 7.1 4.1e-16 59.5 7.1 2.2 1 1 1 2 2 2 1 SNARE associated Golgi protein Syntaxin-18_N PF10496.9 EAU84703.1 - 6e-15 55.3 2.4 1.4e-14 54.1 0.0 2.9 4 1 1 5 5 5 1 SNARE-complex protein Syntaxin-18 N-terminus Ssu72 PF04722.13 EAU84704.2 - 4.5e-86 287.3 0.0 5.7e-86 287.0 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein Zn_clus PF00172.18 EAU84706.2 - 1.6e-07 31.4 13.4 2.5e-07 30.7 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.11 EAU84706.2 - 5 5.3 5.5 6.7 4.9 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) E1-E2_ATPase PF00122.20 EAU84709.1 - 1.9e-35 122.0 22.1 5.2e-28 97.8 0.5 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAU84709.1 - 7.1e-29 100.8 4.4 7.1e-29 100.8 4.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EAU84709.1 - 1.5e-16 59.8 0.1 1.5e-16 59.8 0.1 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EAU84709.1 - 4.3e-16 59.8 0.1 1.5e-14 54.8 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAU84709.1 - 2.6e-14 53.1 0.0 5.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU84709.1 - 0.0021 17.9 0.9 0.007 16.1 0.8 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase COX7C PF02935.16 EAU84710.1 - 6.4e-16 58.4 0.5 7.5e-16 58.1 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc TetR_N PF00440.23 EAU84710.1 - 0.04 13.7 0.7 0.073 12.9 0.7 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Ribonuclease_3 PF00636.26 EAU84711.2 - 1.1e-39 135.2 0.0 2.4e-19 69.9 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EAU84711.2 - 2.1e-26 92.6 0.1 2.9e-09 37.1 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.14 EAU84711.2 - 9.9e-11 41.7 0.0 2.5e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 EAU84711.2 - 7.5e-06 26.3 0.0 1.8e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 EAU84711.2 - 0.0058 16.5 0.1 0.018 14.9 0.1 1.8 1 1 0 1 1 1 1 PAZ domain DEAD PF00270.29 EAU84711.2 - 0.024 14.4 0.1 0.054 13.3 0.1 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ank_3 PF13606.6 EAU84712.1 - 0.066 13.8 0.0 0.18 12.4 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 EAU84712.1 - 0.17 12.5 0.0 0.41 11.3 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Auto_anti-p27 PF06677.12 EAU84716.2 - 2.2e-11 43.7 0.3 2.2e-11 43.7 0.3 2.0 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Glyco_hydro_47 PF01532.20 EAU84717.2 - 3.1e-109 365.9 0.0 4.9e-109 365.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.27 EAU84718.1 - 2.6e-15 56.3 0.1 3.3e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAU84718.1 - 0.017 14.6 0.1 0.029 13.8 0.1 1.6 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase Ribosomal_S3Ae PF01015.18 EAU84719.1 - 7.5e-93 309.7 2.3 9.1e-93 309.4 2.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EAU84719.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region LMP PF04778.12 EAU84719.1 - 0.035 14.0 0.2 0.068 13.1 0.2 1.6 1 0 0 1 1 1 0 LMP repeated region SUI1 PF01253.22 EAU84719.1 - 0.056 14.0 0.2 2 9.0 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor SUI1 Shugoshin_N PF07558.11 EAU84719.1 - 0.094 12.6 0.2 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Dynamin_N PF00350.23 EAU84723.2 - 9.5e-10 38.8 0.7 9.5e-10 38.8 0.7 4.4 2 2 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EAU84723.2 - 0.00068 19.6 0.1 0.0018 18.2 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EAU84723.2 - 0.0012 18.9 0.4 0.018 15.1 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EAU84723.2 - 0.0038 17.5 0.4 0.024 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EAU84723.2 - 0.004 17.7 0.5 0.004 17.7 0.5 3.4 4 1 0 4 4 4 1 ABC transporter Chrome_Resist PF09828.9 EAU84723.2 - 0.3 11.5 2.0 1.2 9.6 2.0 2.1 1 1 0 1 1 1 0 Chromate resistance exported protein AAA_16 PF13191.6 EAU84723.2 - 0.5 10.7 0.0 0.5 10.7 0.0 3.1 4 1 0 4 4 4 0 AAA ATPase domain ATP_bind_1 PF03029.17 EAU84725.1 - 9.8e-78 261.2 0.0 1.3e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EAU84725.1 - 0.0013 19.1 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EAU84725.1 - 0.0041 17.7 0.0 0.0085 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAU84725.1 - 0.0044 16.7 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 EAU84725.1 - 0.0066 15.7 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase T2SSE PF00437.20 EAU84725.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EAU84725.1 - 0.019 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain MeaB PF03308.16 EAU84725.1 - 0.025 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF463 PF04317.12 EAU84725.1 - 0.025 13.5 0.0 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_7 PF12775.7 EAU84725.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EAU84725.1 - 0.057 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAU84725.1 - 0.058 13.6 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAU84725.1 - 0.058 13.7 0.0 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EAU84725.1 - 0.064 13.3 0.0 0.094 12.8 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EAU84725.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EAU84725.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EAU84725.1 - 0.11 12.3 0.1 0.71 9.8 0.0 2.2 3 0 0 3 3 3 0 NTPase CLP1_P PF16575.5 EAU84725.1 - 0.12 12.1 0.0 0.82 9.4 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 EAU84725.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_24 PF13479.6 EAU84725.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EAU84725.1 - 0.2 10.9 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC Mago-bind PF09282.10 EAU84726.1 - 7.7e-14 51.3 1.5 1.4e-13 50.5 1.5 1.4 1 0 0 1 1 1 1 Mago binding NARP1 PF12569.8 EAU84726.1 - 1.8 7.3 8.7 2.2 7.1 8.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ACPS PF01648.20 EAU84730.2 - 3.7e-10 39.9 0.0 5.7e-10 39.3 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily WD40 PF00400.32 EAU84731.2 - 4.1e-31 106.5 16.7 2.1e-08 34.7 0.0 9.7 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84731.2 - 2.2e-08 34.3 0.6 1.3 9.4 0.2 6.1 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU84731.2 - 0.00027 20.0 1.6 4.3 6.2 0.1 5.0 4 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein HMG_box PF00505.19 EAU84736.2 - 9.4e-13 48.4 0.2 1.7e-12 47.5 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU84736.2 - 6.8e-05 23.4 0.0 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain DUF302 PF03625.14 EAU84737.1 - 0.00019 21.2 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 DEAD PF00270.29 EAU84738.2 - 5.4e-39 133.8 0.0 1e-38 132.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU84738.2 - 3.2e-25 88.6 0.0 1.1e-24 86.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU84738.2 - 0.0032 17.5 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAU84738.2 - 0.05 13.9 0.2 0.27 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain Mob1_phocein PF03637.17 EAU84740.2 - 1.5e-79 265.9 0.0 1.8e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DJ-1_PfpI PF01965.24 EAU84741.2 - 1.7e-12 47.4 0.0 4e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EAU84741.2 - 6.4e-06 26.0 0.0 7.1e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like RRM_1 PF00076.22 EAU84742.2 - 2.8e-09 36.7 0.1 8.4e-09 35.1 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAU84742.2 - 0.028 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pes-10 PF07149.11 EAU84742.2 - 0.078 12.0 2.2 0.1 11.6 2.2 1.1 1 0 0 1 1 1 0 Pes-10 TRAM_LAG1_CLN8 PF03798.16 EAU84743.1 - 5.1e-48 163.5 25.8 7.1e-48 163.0 25.8 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EAU84743.1 - 1.1e-07 31.3 0.0 1.1e-07 31.3 0.0 2.5 3 0 0 3 3 3 1 TRAM1-like protein Snf7 PF03357.21 EAU84744.1 - 7.1e-38 129.9 23.1 7.1e-38 129.9 23.1 1.3 1 1 0 1 1 1 1 Snf7 EPOP PF15223.6 EAU84744.1 - 0.036 13.4 2.7 0.047 13.1 2.7 1.2 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein Ribosomal_L29 PF00831.23 EAU84744.1 - 0.062 13.3 1.1 0.062 13.3 1.1 3.4 3 1 1 4 4 4 0 Ribosomal L29 protein Hydantoinase_B PF02538.14 EAU84744.1 - 0.15 10.4 2.1 0.17 10.2 1.3 1.4 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase NIF PF03031.18 EAU84745.2 - 5.3e-52 175.7 0.0 7.2e-52 175.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3580 PF12117.8 EAU84745.2 - 0.65 10.2 3.1 5.3 7.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) MFS_1 PF07690.16 EAU84746.2 - 3.9e-41 141.2 34.2 1.3e-38 132.8 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C3HC4 PF00097.25 EAU84747.1 - 4.1e-05 23.4 0.4 0.00014 21.6 0.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU84747.1 - 0.00036 20.8 6.7 0.00084 19.6 2.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EAU84747.1 - 0.0017 18.2 3.6 0.0044 16.8 1.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EAU84747.1 - 0.0021 17.8 1.8 0.0057 16.4 0.6 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EAU84747.1 - 0.004 17.1 2.3 0.046 13.8 1.9 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAU84747.1 - 0.0052 16.8 0.8 0.81 9.8 0.5 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EAU84747.1 - 0.0084 16.4 4.6 0.07 13.4 4.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EAU84747.1 - 0.014 15.2 2.1 0.014 15.2 2.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU84747.1 - 0.082 12.8 0.5 0.082 12.8 0.5 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAU84747.1 - 0.23 11.6 3.8 0.12 12.5 0.9 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-met2 PF12907.7 EAU84747.1 - 0.34 11.1 1.7 20 5.4 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding zf-RING_5 PF14634.6 EAU84747.1 - 0.42 10.6 3.7 1 9.4 2.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain tRNA-synt_2c PF01411.19 EAU84748.2 - 2e-05 23.3 0.0 2.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EAU84748.2 - 0.0024 17.9 0.0 0.0063 16.6 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Mannosidase_ig PF17786.1 EAU84749.2 - 2.1e-20 73.1 0.3 8.4e-20 71.2 0.1 2.2 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 EAU84749.2 - 1.6e-06 27.8 0.0 4.7e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 EAU84749.2 - 0.0011 18.1 0.6 0.0058 15.8 0.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EAU84749.2 - 0.029 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain Ras PF00071.22 EAU84750.1 - 2.6e-47 160.4 0.2 3.1e-47 160.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU84750.1 - 6.6e-16 58.6 0.0 1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU84750.1 - 0.00023 20.7 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAU84750.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 EAU84750.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EAU84750.1 - 0.0077 15.8 0.3 0.026 14.1 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAU84750.1 - 0.013 15.5 0.2 3.7 7.4 0.0 2.3 1 1 1 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EAU84750.1 - 0.013 14.9 0.1 0.016 14.6 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Spo12 PF05032.12 EAU84751.1 - 2.5e-15 56.1 0.7 2.5e-15 56.1 0.7 1.7 2 0 0 2 2 2 1 Spo12 family zf-RING_5 PF14634.6 EAU84752.2 - 5.4e-06 26.3 3.3 6.4e-05 22.8 3.3 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAU84752.2 - 5.5e-06 26.6 6.0 7.3e-06 26.2 2.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EAU84752.2 - 7.8e-06 25.7 4.5 3.4e-05 23.6 4.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU84752.2 - 9.5e-06 25.4 2.0 3.2e-05 23.7 0.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU84752.2 - 1.9e-05 24.4 1.8 1.9e-05 24.4 1.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU84752.2 - 0.00017 21.8 6.3 0.00029 21.0 6.3 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EAU84752.2 - 0.00017 21.4 1.2 0.00017 21.4 1.2 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C2HC5 PF06221.13 EAU84752.2 - 0.00047 20.1 0.5 0.0031 17.5 0.2 2.0 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-C3HC4_4 PF15227.6 EAU84752.2 - 0.00061 19.9 0.3 0.00061 19.9 0.3 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EAU84752.2 - 0.00078 19.5 0.8 0.0055 16.7 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EAU84752.2 - 0.0012 18.9 5.0 0.016 15.2 5.1 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 EAU84752.2 - 0.0042 16.8 2.2 0.0068 16.2 0.8 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EAU84752.2 - 0.0044 16.8 0.3 0.0074 16.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 EAU84752.2 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Chitin_synth_1 PF01644.17 EAU84753.2 - 2.2e-67 226.1 0.0 3.7e-67 225.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EAU84753.2 - 4.9e-28 96.9 0.2 8.6e-28 96.1 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EAU84753.2 - 3.1e-26 92.1 0.0 1.1e-19 70.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAU84753.2 - 3.4e-10 40.2 0.4 1.1e-09 38.4 0.4 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 GST_N_3 PF13417.6 EAU84754.2 - 1.9e-13 50.6 0.1 4e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU84754.2 - 2.2e-05 24.7 0.0 5.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain zf-CCHC PF00098.23 EAU84755.2 - 1.9e-19 68.7 21.5 7.2e-09 35.3 2.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 EAU84755.2 - 5.3e-06 26.3 2.3 0.26 11.3 1.4 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 EAU84755.2 - 5e-05 22.9 14.4 0.024 14.3 0.9 3.6 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 EAU84755.2 - 0.0031 17.2 8.3 0.55 10.0 0.3 3.2 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.6 EAU84755.2 - 2.2 8.2 15.1 1.2 9.0 2.3 3.3 3 0 0 3 3 3 0 Zinc knuckle TRAF6_Z2 PF18048.1 EAU84755.2 - 3.7 7.7 6.4 1.3 9.2 0.6 2.6 2 1 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 14-3-3 PF00244.20 EAU84756.2 - 2.1e-52 177.8 0.1 2.6e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DS PF01916.17 EAU84757.1 - 2.9e-136 453.4 0.0 3.3e-136 453.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase SpuA_C PF18033.1 EAU84757.1 - 0.19 11.8 0.1 6.8 6.8 0.0 2.3 2 0 0 2 2 2 0 SpuA C-terminal Sec7 PF01369.20 EAU84758.2 - 6.4e-69 231.3 0.0 1.6e-68 230.0 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EAU84758.2 - 3.9e-38 130.8 0.7 3.9e-38 130.8 0.7 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EAU84758.2 - 1.6e-30 104.8 0.1 1.6e-30 104.8 0.1 5.8 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 EAU84758.2 - 1.7e-21 76.7 5.0 1.7e-20 73.5 0.5 3.6 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 YmgB PF10798.8 EAU84758.2 - 0.11 12.3 0.3 13 5.7 0.0 3.3 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR SH3_9 PF14604.6 EAU84759.2 - 1.7e-39 133.4 7.1 5.9e-16 58.1 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 EAU84759.2 - 7.6e-39 131.1 5.3 3.3e-16 58.6 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 EAU84759.2 - 6.2e-30 102.8 0.0 1.4e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 EAU84759.2 - 1.5e-23 82.2 0.1 5.1e-08 32.5 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.11 EAU84759.2 - 2e-05 24.8 2.1 1.2 9.5 0.0 3.5 3 0 0 3 3 3 2 Bacterial SH3 domain ERM PF00769.19 EAU84759.2 - 2.5e-05 24.2 18.6 2.5e-05 24.2 18.6 2.0 3 0 0 3 3 3 1 Ezrin/radixin/moesin family SH3_10 PF17902.1 EAU84759.2 - 0.00012 22.1 0.5 0.029 14.4 0.0 2.9 3 0 0 3 3 2 1 SH3 domain SAM_4 PF18017.1 EAU84759.2 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1720 PF08226.11 EAU84759.2 - 0.0089 16.4 25.0 0.0089 16.4 25.0 6.2 1 1 2 3 3 2 1 Domain of unknown function (DUF1720) hSH3 PF14603.6 EAU84759.2 - 0.011 16.2 0.0 0.047 14.1 0.0 2.1 1 0 0 1 1 1 0 Helically-extended SH3 domain CAF-1_p150 PF11600.8 EAU84759.2 - 0.026 14.2 35.8 0.073 12.8 35.8 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAM_1 PF00536.30 EAU84759.2 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) RR_TM4-6 PF06459.12 EAU84759.2 - 3.7 7.3 13.6 8.8 6.1 13.6 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GTP_EFTU PF00009.27 EAU84760.1 - 2.3e-45 154.5 0.1 4.2e-45 153.7 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAU84760.1 - 2.1e-36 124.7 0.3 2.9e-35 120.9 0.1 2.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAU84760.1 - 3.7e-09 36.8 0.1 1.2e-08 35.2 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAU84760.1 - 0.0011 19.1 0.1 0.0079 16.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 EAU84760.1 - 0.19 11.5 1.3 0.37 10.6 0.1 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RTP1_C1 PF10363.9 EAU84761.2 - 7.7e-33 113.0 0.0 3.3e-31 107.8 0.0 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EAU84761.2 - 0.00048 20.1 0.5 6.4 7.3 0.0 6.2 7 0 0 7 7 7 1 HEAT repeat CarbopepD_reg_2 PF13715.6 EAU84761.2 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Urb2 PF10441.9 EAU84761.2 - 0.012 15.5 0.0 0.041 13.8 0.0 1.9 1 0 0 1 1 1 0 Urb2/Npa2 family Tti2 PF10521.9 EAU84761.2 - 0.019 14.5 0.1 6.6 6.2 0.0 2.9 2 0 0 2 2 2 0 Tti2 family RTP1_C2 PF10304.9 EAU84761.2 - 0.15 11.7 0.0 0.52 10.1 0.0 1.9 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 EAU84761.2 - 0.55 10.8 8.5 0.74 10.4 0.0 5.1 7 1 1 8 8 8 0 HEAT-like repeat UQ_con PF00179.26 EAU84763.2 - 2.2e-21 76.0 0.0 4e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 EAU84763.2 - 0.00024 21.3 1.2 0.00053 20.2 1.2 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DUF3287 PF11690.8 EAU84763.2 - 0.077 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Nop14 PF04147.12 EAU84763.2 - 0.24 9.6 4.7 0.39 8.9 4.7 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EAU84763.2 - 0.99 7.4 10.4 1.7 6.7 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi PepSY_TM PF03929.16 EAU84764.1 - 0.041 13.5 0.1 0.041 13.5 0.1 1.9 2 1 0 2 2 2 0 PepSY-associated TM region Opy2 PF09463.10 EAU84764.1 - 0.06 13.7 15.1 0.093 13.1 15.1 1.3 1 0 0 1 1 1 0 Opy2 protein DUF1216 PF06746.11 EAU84764.1 - 0.097 12.7 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) ABC_tran PF00005.27 EAU84765.2 - 1.2e-14 55.0 0.0 4.9e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU84765.2 - 3.8e-07 30.2 5.8 0.00011 22.1 0.8 2.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAU84765.2 - 0.00077 19.1 0.1 0.0016 18.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EAU84765.2 - 0.0014 18.2 0.7 0.0044 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EAU84765.2 - 0.0017 17.8 0.1 0.67 9.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAU84765.2 - 0.0023 17.8 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EAU84765.2 - 0.0066 16.2 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EAU84765.2 - 0.013 16.1 0.1 0.027 15.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EAU84765.2 - 0.039 13.7 0.1 0.1 12.3 0.1 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EAU84765.2 - 0.047 13.9 0.9 0.07 13.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EAU84765.2 - 0.056 13.5 0.2 0.095 12.8 0.2 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EAU84765.2 - 0.11 12.4 0.2 0.37 10.7 0.2 1.7 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 EAU84765.2 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.6 EAU84765.2 - 0.22 11.8 0.7 0.49 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EAU84765.2 - 0.24 11.4 0.2 0.38 10.8 0.2 1.3 1 0 0 1 1 1 0 Dynamin family AAA_5 PF07728.14 EAU84765.2 - 0.29 11.1 1.2 1.6 8.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) zf-CCHC PF00098.23 EAU84766.2 - 0.00066 19.6 3.3 0.00066 19.6 3.3 5.2 6 0 0 6 6 6 2 Zinc knuckle zf-CCHC_3 PF13917.6 EAU84766.2 - 2.3 8.3 25.7 0.64 10.0 3.1 4.8 3 1 1 4 4 4 0 Zinc knuckle UQ_con PF00179.26 EAU84767.2 - 9.8e-14 51.2 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAU84767.2 - 0.015 15.5 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain His_Phos_2 PF00328.22 EAU84768.2 - 3.1e-87 293.4 0.3 4.2e-87 293.0 0.3 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EAU84768.2 - 2.5e-36 123.7 0.0 6.1e-36 122.4 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EAU84768.2 - 6.7e-06 25.8 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain AMP-binding PF00501.28 EAU84769.2 - 5.3e-91 305.3 0.1 3.3e-47 161.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EAU84769.2 - 6.9e-11 43.0 1.4 1.5e-10 41.9 1.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGAP_C PF03836.15 EAU84770.2 - 4e-44 150.1 0.7 4e-44 150.1 0.7 2.4 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 EAU84770.2 - 1.4e-38 132.7 0.0 3.6e-38 131.4 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EAU84770.2 - 5.5e-25 84.8 59.5 0.008 15.9 0.1 14.0 13 0 0 13 13 13 12 IQ calmodulin-binding motif CH PF00307.31 EAU84770.2 - 4.6e-13 49.3 1.4 1.8e-12 47.4 0.0 2.6 3 0 0 3 3 3 1 Calponin homology (CH) domain ATP_sub_h PF10775.9 EAU84770.2 - 0.064 13.3 0.2 3.7 7.6 0.1 3.1 2 0 0 2 2 2 0 ATP synthase complex subunit h Sipho_Gp157 PF05565.11 EAU84770.2 - 1.1 9.2 6.1 0.39 10.7 1.1 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 Kelch_4 PF13418.6 EAU84773.2 - 8.7e-21 73.7 7.3 3e-06 27.1 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EAU84773.2 - 3.4e-16 59.1 18.0 0.00025 21.3 0.1 7.3 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EAU84773.2 - 5.1e-08 32.9 3.7 1.7 9.1 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 EAU84773.2 - 1.3e-06 27.9 1.0 2.2 7.9 0.0 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 EAU84773.2 - 2.5e-05 24.2 1.1 10 6.2 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EAU84773.2 - 0.13 12.3 2.4 17 5.6 0.0 4.4 5 0 0 5 5 5 0 Kelch motif OppC_N PF12911.7 EAU84773.2 - 7.5 6.6 8.1 12 6.0 0.1 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C zf-C2H2 PF00096.26 EAU84774.2 - 3.6e-06 27.1 9.2 0.00022 21.5 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU84774.2 - 4.4e-05 24.0 13.6 0.017 15.9 0.7 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU84774.2 - 0.00038 20.7 15.1 0.0063 16.9 0.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 EAU84774.2 - 0.079 13.4 1.4 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.14 EAU84774.2 - 0.11 12.3 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 EAU84774.2 - 0.12 12.7 2.9 0.83 10.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-FPG_IleRS PF06827.14 EAU84774.2 - 1.1 9.2 4.8 0.43 10.5 0.3 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DZR PF12773.7 EAU84774.2 - 2.2 8.4 8.6 24 5.1 8.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon Cid2 PF09774.9 EAU84775.2 - 1.2e-17 64.8 7.9 5.1e-17 62.7 7.9 1.8 1 1 0 1 1 1 1 Caffeine-induced death protein 2 GILT PF03227.16 EAU84776.2 - 3.3e-12 46.6 0.1 3.3e-12 46.6 0.1 1.5 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF19 PF01579.18 EAU84776.2 - 0.33 10.7 3.1 0.35 10.7 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF19) Ribosomal_L22 PF00237.19 EAU84777.1 - 1.2e-20 73.7 0.1 1.2e-20 73.7 0.1 2.0 3 0 0 3 3 3 1 Ribosomal protein L22p/L17e PUB_1 PF18486.1 EAU84777.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain IHABP4_N PF16174.5 EAU84777.1 - 1.7 9.3 5.9 0.37 11.4 2.3 1.7 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Ribophorin_I PF04597.14 EAU84778.1 - 1.1e-132 443.4 2.5 1.2e-132 443.3 2.5 1.0 1 0 0 1 1 1 1 Ribophorin I PPR_2 PF13041.6 EAU84780.1 - 1e-19 70.4 0.2 1.4e-12 47.6 0.1 4.8 5 0 0 5 5 5 3 PPR repeat family PPR PF01535.20 EAU84780.1 - 4.2e-14 51.7 0.1 0.0056 16.9 0.0 5.0 5 0 0 5 5 5 4 PPR repeat PPR_1 PF12854.7 EAU84780.1 - 0.0011 18.6 0.5 0.031 14.0 0.1 3.0 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.6 EAU84780.1 - 0.0036 18.0 0.0 13 7.0 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR_3 PF13812.6 EAU84780.1 - 0.0075 16.3 0.0 12 6.1 0.0 3.7 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EAU84780.1 - 0.055 12.8 0.0 15 4.9 0.0 3.2 3 1 1 4 4 4 0 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 EAU84780.1 - 0.061 13.8 0.0 1.6 9.3 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps54 PF07928.12 EAU84780.1 - 0.5 10.8 2.2 2.6 8.5 0.6 2.2 2 0 0 2 2 2 0 Vps54-like protein Asp PF00026.23 EAU84781.1 - 9.4e-27 94.2 0.0 1.5e-24 87.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EAU84781.1 - 0.00026 21.6 0.1 1.9 9.2 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.6 EAU84781.1 - 0.061 13.6 0.2 2.7 8.2 0.0 2.8 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal Fe-ADH PF00465.19 EAU84782.1 - 4.8e-90 302.0 0.0 6.1e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAU84782.1 - 4.6e-12 46.2 0.0 7.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase His_biosynth PF00977.21 EAU84783.2 - 4.9e-36 124.3 0.0 6.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_L29 PF00831.23 EAU84784.1 - 3.2e-19 68.7 7.1 3.5e-19 68.5 1.1 2.2 2 0 0 2 2 2 2 Ribosomal L29 protein MRP-L47 PF06984.13 EAU84784.1 - 0.0077 16.3 1.6 0.0098 16.0 0.2 1.8 2 1 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Pkinase PF00069.25 EAU84785.2 - 2.2e-70 237.0 0.0 3e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84785.2 - 5.2e-47 160.3 0.0 7.3e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU84785.2 - 0.00022 20.7 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAU84785.2 - 0.00077 18.3 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU84785.2 - 0.03 14.2 0.0 9 6.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Apolipoprotein PF01442.18 EAU84786.1 - 5.4e-08 32.9 3.6 3.2e-06 27.1 1.4 2.7 2 2 0 2 2 2 1 Apolipoprotein A1/A4/E domain Perilipin PF03036.16 EAU84786.1 - 4.5e-06 26.0 18.3 1.3e-05 24.5 0.4 2.6 1 1 1 2 2 2 1 Perilipin family DUF1640 PF07798.11 EAU84786.1 - 0.0094 16.0 3.4 0.02 15.0 3.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ApoLp-III PF07464.11 EAU84786.1 - 0.018 15.1 16.1 0.21 11.7 0.4 4.1 2 1 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) ATP-synt_D PF01813.17 EAU84786.1 - 0.021 14.7 0.8 0.05 13.4 0.8 1.7 1 0 0 1 1 1 0 ATP synthase subunit D DUF29 PF01724.16 EAU84786.1 - 0.022 15.0 1.9 0.022 15.0 1.9 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF29 Baculo_PEP_C PF04513.12 EAU84786.1 - 0.085 12.9 14.8 3.5 7.6 8.0 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.13 EAU84786.1 - 0.21 12.2 3.7 29 5.3 0.0 3.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Collagen_mid PF15984.5 EAU84786.1 - 0.23 11.2 3.9 0.53 10.0 3.9 1.7 1 1 0 1 1 1 0 Bacterial collagen, middle region DUF4088 PF13317.6 EAU84786.1 - 0.32 10.5 3.3 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) Prominin PF05478.11 EAU84786.1 - 0.4 8.6 6.7 0.19 9.6 4.0 1.8 2 0 0 2 2 2 0 Prominin Baculo_p24 PF05073.12 EAU84786.1 - 0.42 10.4 4.3 0.66 9.7 2.9 2.0 2 0 0 2 2 2 0 Baculovirus P24 capsid protein Fzo_mitofusin PF04799.13 EAU84786.1 - 3 7.4 9.5 14 5.2 8.9 2.3 2 1 0 2 2 2 0 fzo-like conserved region Muted PF14942.6 EAU84786.1 - 3.2 8.1 7.4 16 5.9 0.2 2.5 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1690 PF07956.11 EAU84786.1 - 6.6 7.1 12.7 1 9.8 5.5 3.1 3 1 1 4 4 4 0 Protein of Unknown function (DUF1690) PIN_8 PF18476.1 EAU84786.1 - 7.6 6.3 8.0 5.2 6.9 4.8 2.2 1 1 1 2 2 2 0 PIN like domain Polysacc_deac_1 PF01522.21 EAU84787.1 - 4.6e-20 71.8 0.0 7.8e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase AAA PF00004.29 EAU84789.2 - 6e-06 26.7 2.0 5.9e-05 23.5 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EAU84789.2 - 0.0012 18.8 0.1 0.39 10.6 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_5 PF07728.14 EAU84789.2 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU84789.2 - 0.014 15.7 0.0 0.045 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EAU84789.2 - 0.018 14.6 0.3 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EAU84789.2 - 0.065 13.0 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EAU84789.2 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 EAU84789.2 - 0.13 11.4 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 EAU84789.2 - 0.19 12.0 0.0 0.57 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ribosomal_L7Ae PF01248.26 EAU84790.2 - 8e-14 51.2 0.1 1.8e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PRKG1_interact PF15898.5 EAU84790.2 - 6.1 7.8 10.7 2.4 9.1 0.8 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RFX_DNA_binding PF02257.15 EAU84792.2 - 1.2e-27 96.3 0.1 2.4e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain DEAD PF00270.29 EAU84793.2 - 3.9e-41 140.8 0.1 1.3e-40 139.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EAU84793.2 - 4.7e-24 84.4 0.1 1.1e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EAU84793.2 - 3.8e-20 72.3 0.0 9.3e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU84793.2 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAU84793.2 - 0.0028 16.9 0.9 0.025 13.8 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EAU84793.2 - 0.088 13.1 0.6 0.6 10.4 0.2 2.6 2 1 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 EAU84793.2 - 0.17 11.3 3.6 0.53 9.8 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1682 PF07946.14 EAU84796.2 - 1.3e-85 287.5 0.6 1.6e-85 287.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2992 PF11208.8 EAU84796.2 - 6.8 6.9 18.2 9.8 6.4 18.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) G6PD_C PF02781.16 EAU84798.1 - 5.5e-112 373.7 0.0 8.6e-112 373.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EAU84798.1 - 9.5e-60 202.2 0.0 1.4e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FmiP_Thoc5 PF09766.9 EAU84799.1 - 4.6e-34 118.3 14.4 5.6e-34 118.0 14.4 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Mod_r PF07200.13 EAU84799.1 - 0.0024 18.0 11.0 0.0028 17.8 4.1 2.2 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein CREPT PF16566.5 EAU84799.1 - 0.033 14.4 7.2 0.056 13.6 1.6 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2935 PF11155.8 EAU84799.1 - 0.043 14.1 2.8 0.063 13.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF948 PF06103.11 EAU84799.1 - 0.067 13.5 1.0 7.6 6.9 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM76 PF16046.5 EAU84799.1 - 0.24 10.7 4.7 0.32 10.3 4.7 1.1 1 0 0 1 1 1 0 FAM76 protein T3SSipB PF16535.5 EAU84799.1 - 1.4 9.3 9.8 1.7 9.1 1.3 2.4 2 1 0 2 2 2 0 Type III cell invasion protein SipB DUF4559 PF15112.6 EAU84799.1 - 1.8 8.2 9.2 2.9 7.5 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) FlaC_arch PF05377.11 EAU84799.1 - 3.3 8.2 5.4 0.77 10.2 0.6 2.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) UQ_con PF00179.26 EAU84800.2 - 2.6e-39 134.1 0.1 3.2e-39 133.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uteroglobin PF01099.17 EAU84800.2 - 0.1 12.9 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 Uteroglobin family ThrE PF06738.12 EAU84801.2 - 0.0077 15.6 1.8 0.0091 15.4 1.8 1.1 1 0 0 1 1 1 1 Putative threonine/serine exporter ThrE_2 PF12821.7 EAU84801.2 - 0.015 15.4 0.4 0.025 14.7 0.4 1.3 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE EamA PF00892.20 EAU84801.2 - 0.017 15.3 2.9 0.023 14.9 2.9 1.1 1 0 0 1 1 1 0 EamA-like transporter family MARVEL PF01284.23 EAU84802.1 - 1.7e-05 24.9 12.3 2.3e-05 24.5 12.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain HlyIII PF03006.20 EAU84802.1 - 0.66 9.6 9.1 0.16 11.6 5.2 1.8 2 0 0 2 2 2 0 Haemolysin-III related Spore_YabQ PF09578.10 EAU84802.1 - 8 6.8 13.3 0.71 10.1 5.7 2.5 2 1 1 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) Mucin PF01456.17 EAU84803.2 - 0.0054 16.7 0.5 0.014 15.4 0.2 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF3810 PF12725.7 EAU84803.2 - 0.1 11.9 1.0 10 5.3 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) MARVEL PF01284.23 EAU84803.2 - 0.13 12.3 14.8 7.9 6.5 15.6 2.2 1 1 1 2 2 2 0 Membrane-associating domain DUF2070 PF09843.9 EAU84803.2 - 1.5 7.0 6.2 1.9 6.7 6.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Oxidored_q3 PF00499.20 EAU84803.2 - 3.1 7.5 9.6 7.9 6.2 9.8 1.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 LETM1 PF07766.13 EAU84803.2 - 6.2 6.1 6.0 0.53 9.6 1.4 1.4 2 0 0 2 2 2 0 LETM1-like protein ABC2_membrane_2 PF12679.7 EAU84803.2 - 6.7 5.9 14.1 21 4.3 14.1 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4131 PF13567.6 EAU84803.2 - 8.1 6.1 10.2 3.1 7.4 4.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) AMP-binding PF00501.28 EAU84804.2 - 2.4e-37 128.5 0.0 3.7e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EAU84804.2 - 1.3e-06 28.2 2.0 2.7e-06 27.2 2.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus SpoIIP PF07454.11 EAU84805.2 - 0.0084 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Pkinase PF00069.25 EAU84806.2 - 3.7e-65 219.9 0.2 1.6e-43 149.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84806.2 - 3.5e-28 98.6 0.1 6.7e-21 74.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EAU84806.2 - 2.3e-06 26.8 0.1 3.1e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAU84806.2 - 9.7e-05 21.8 0.2 0.00032 20.1 0.0 1.9 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU84806.2 - 0.00014 21.9 0.1 0.014 15.4 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAU84806.2 - 0.0083 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 EAU84806.2 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EAU84806.2 - 0.016 14.6 0.2 0.058 12.7 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 EAU84806.2 - 0.043 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAU84806.2 - 0.05 12.4 0.5 0.1 11.4 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase Pkinase_C PF00433.24 EAU84806.2 - 0.15 12.8 1.3 0.37 11.5 1.3 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain Prefoldin_2 PF01920.20 EAU84807.1 - 1.3e-22 79.8 9.0 1.5e-22 79.5 9.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 EAU84807.1 - 0.0016 18.1 6.8 0.052 13.3 0.6 2.1 2 0 0 2 2 2 2 Septum formation initiator DUF4988 PF16378.5 EAU84807.1 - 0.0092 15.7 1.8 0.42 10.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF2089 PF09862.9 EAU84807.1 - 0.018 15.1 1.0 0.027 14.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Laminin_II PF06009.12 EAU84807.1 - 0.022 14.8 3.4 1.7 8.7 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 EAU84807.1 - 0.035 14.6 1.5 0.56 10.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.17 EAU84807.1 - 0.036 14.0 6.9 0.17 11.8 0.1 2.1 1 1 0 2 2 2 0 Prefoldin subunit DASH_Dad4 PF08650.10 EAU84807.1 - 0.037 14.0 1.3 6.5 6.8 0.1 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF4600 PF15372.6 EAU84807.1 - 0.07 13.6 4.7 0.12 12.8 4.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) XhlA PF10779.9 EAU84807.1 - 0.076 13.2 5.3 0.21 11.8 0.7 2.3 2 0 0 2 2 2 0 Haemolysin XhlA I_LWEQ PF01608.17 EAU84807.1 - 0.13 12.5 6.2 2.1 8.6 0.4 2.0 2 0 0 2 2 2 0 I/LWEQ domain Spore_III_AB PF09548.10 EAU84807.1 - 0.16 12.1 3.3 0.2 11.7 3.3 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Spc24 PF08286.11 EAU84807.1 - 0.18 12.0 5.9 0.97 9.7 1.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 BLOC1_2 PF10046.9 EAU84807.1 - 0.22 11.8 7.0 3.3 8.1 1.5 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 EAU84807.1 - 0.22 11.6 8.0 0.27 11.3 8.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 EAU84807.1 - 0.27 9.1 3.1 0.31 8.9 3.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 EAU84807.1 - 0.53 10.5 8.1 1.4 9.2 1.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Nsp1_C PF05064.13 EAU84807.1 - 0.66 9.8 8.1 0.2 11.4 1.5 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region Plk4_PB2 PF18409.1 EAU84807.1 - 0.75 10.5 3.3 37 5.1 3.3 2.1 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 KfrA_N PF11740.8 EAU84807.1 - 2.7 8.7 7.8 2.5 8.8 6.0 1.8 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Med4 PF10018.9 EAU84807.1 - 6 6.5 9.2 0.75 9.4 3.0 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 HypA PF01155.19 EAU84808.1 - 0.051 13.6 0.0 0.099 12.7 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA VTC PF09359.10 EAU84808.1 - 0.085 12.2 0.1 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 VTC domain INO80_Ies4 PF08193.11 EAU84808.1 - 0.51 10.3 7.2 0.16 12.0 4.1 1.6 1 1 0 1 1 1 0 INO80 complex subunit Ies4 TCTP PF00838.17 EAU84809.1 - 6.5e-69 231.5 1.4 7.2e-69 231.4 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UTP15_C PF09384.10 EAU84810.1 - 5.8e-48 162.3 0.2 9.4e-48 161.6 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EAU84810.1 - 2.8e-22 78.6 2.8 0.00062 20.5 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU84810.1 - 3e-08 33.8 0.0 0.078 13.3 0.0 4.8 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EAU84810.1 - 0.0048 15.5 0.1 0.035 12.7 0.1 2.2 2 1 1 3 3 3 1 Cytochrome D1 heme domain Nup160 PF11715.8 EAU84810.1 - 0.013 14.1 0.9 1.2 7.7 0.3 2.4 1 1 0 2 2 2 0 Nucleoporin Nup120/160 CTNNBL PF08216.11 EAU84811.2 - 5.3e-35 119.7 0.7 2.6e-34 117.5 0.0 2.4 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.8 EAU84811.2 - 0.13 12.2 0.0 0.42 10.5 0.0 1.7 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central FAT PF02259.23 EAU84812.2 - 3.1e-62 210.8 3.5 6.8e-62 209.7 3.5 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EAU84812.2 - 5.1e-21 75.6 0.0 1.2e-20 74.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_2 PF07719.17 EAU84812.2 - 0.00013 21.8 0.1 0.0066 16.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU84812.2 - 0.0027 17.5 0.1 0.045 13.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU84812.2 - 0.034 14.3 0.0 0.034 14.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Homeobox_KN PF05920.11 EAU84812.2 - 0.057 13.3 0.1 0.19 11.7 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain TPR_11 PF13414.6 EAU84812.2 - 0.13 12.0 0.0 0.4 10.4 0.0 1.9 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.6 EAU84812.2 - 0.18 12.7 6.2 0.05 14.4 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp PF00026.23 EAU84813.1 - 4.9e-113 377.7 0.1 5.8e-113 377.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU84813.1 - 4.5e-13 49.8 3.5 1e-11 45.4 2.1 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EAU84813.1 - 3.8e-05 23.5 0.0 0.00079 19.2 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EAU84813.1 - 0.00032 21.3 0.1 0.68 10.6 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EAU84813.1 - 0.0026 18.3 0.1 5 7.7 0.0 2.7 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease BCDHK_Adom3 PF10436.9 EAU84818.1 - 1.4e-41 142.0 0.0 2.3e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EAU84818.1 - 5.1e-08 33.4 0.0 1.3e-06 28.9 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EAU84818.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PCI PF01399.27 EAU84822.1 - 5.4e-11 42.9 0.0 4.9e-10 39.9 0.0 2.5 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.9 EAU84822.1 - 0.032 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 RdRP PF05183.12 EAU84823.2 - 1.3e-126 423.6 0.0 1.6e-126 423.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase HJURP_mid PF12346.8 EAU84823.2 - 0.4 11.1 0.1 0.4 11.1 0.1 2.3 3 0 0 3 3 3 0 Holliday junction recognition protein-associated repeat GCP_N_terminal PF17681.1 EAU84824.2 - 2.6e-85 286.7 0.1 7.8e-66 222.8 0.0 3.6 2 1 0 2 2 2 2 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EAU84824.2 - 1.2e-83 281.1 4.0 1.2e-83 281.1 4.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Thioredoxin PF00085.20 EAU84825.1 - 1.2e-60 201.9 0.6 4.6e-32 110.1 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EAU84825.1 - 7.2e-39 133.6 0.1 3.1e-31 108.7 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EAU84825.1 - 3e-09 36.9 0.1 0.00021 21.4 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EAU84825.1 - 6.3e-08 32.8 0.4 0.065 13.6 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EAU84825.1 - 8.7e-08 32.6 1.1 0.043 14.3 0.1 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.17 EAU84825.1 - 1.2e-06 27.8 0.2 2.4e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.21 EAU84825.1 - 6.6e-06 26.1 0.7 0.098 12.6 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 EAU84825.1 - 0.0011 18.7 1.6 1.5 8.5 0.0 2.9 3 0 0 3 3 3 2 Redoxin OST3_OST6 PF04756.13 EAU84825.1 - 0.0043 16.5 0.3 0.36 10.1 0.0 3.0 2 1 1 3 3 3 1 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 EAU84825.1 - 0.011 15.9 0.8 6.3 6.9 0.0 3.3 2 1 0 2 2 2 0 Thioredoxin AbiEi_4 PF13338.6 EAU84825.1 - 0.2 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin Glutaredoxin PF00462.24 EAU84825.1 - 0.38 11.0 3.3 6.6 7.0 0.1 3.1 2 1 0 2 2 2 0 Glutaredoxin RRM_1 PF00076.22 EAU84826.2 - 1.2e-13 50.7 0.0 2.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L5e PF17144.4 EAU84827.1 - 7.3e-81 270.0 0.1 1.1e-80 269.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EAU84827.1 - 2.6e-36 124.4 2.8 2.6e-36 124.4 2.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Med17 PF10156.9 EAU84828.2 - 7.9e-38 130.3 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex RalF_SCD PF18248.1 EAU84828.2 - 0.042 13.8 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain TPR_19 PF14559.6 EAU84828.2 - 0.093 13.3 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EAU84829.2 - 7.5e-16 58.0 0.1 1.3e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain XOO_2897-deam PF14440.6 EAU84829.2 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Snf7 PF03357.21 EAU84830.1 - 1.3e-30 106.3 24.2 1.3e-30 106.3 24.2 1.6 1 1 0 1 1 1 1 Snf7 E2F_CC-MB PF16421.5 EAU84830.1 - 8.6 6.8 10.5 0.2 12.0 2.4 2.4 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain LUC7 PF03194.15 EAU84830.1 - 9.7 5.8 17.5 0.072 12.7 6.5 2.2 1 1 1 2 2 2 0 LUC7 N_terminus Iso_dh PF00180.20 EAU84831.1 - 7.1e-94 314.8 0.0 1.2e-93 314.1 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.19 EAU84832.1 - 8.8e-101 337.5 0.0 1.6e-100 336.7 0.0 1.4 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 EAU84832.1 - 2e-25 88.9 0.1 5.3e-25 87.6 0.1 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EAU84832.1 - 8.7e-25 86.6 0.0 1.8e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EAU84832.1 - 0.00022 21.3 0.0 0.069 13.3 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 EAU84832.1 - 0.00064 19.6 0.4 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 EAU84832.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain VID27 PF08553.10 EAU84835.1 - 8.9e-171 567.7 1.0 1.3e-170 567.2 1.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EAU84835.1 - 2.3e-55 187.1 0.4 2.3e-55 187.1 0.4 2.9 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 EAU84835.1 - 1.2e-25 89.8 0.7 4e-25 88.2 0.7 1.9 1 0 0 1 1 1 1 VID27 PH-like domain PI3K_p85B PF02192.16 EAU84835.1 - 0.015 15.0 0.4 0.037 13.8 0.4 1.6 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain DUF1282 PF06930.12 EAU84836.2 - 0.002 18.0 0.5 0.0023 17.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Nop14 PF04147.12 EAU84839.1 - 0.053 11.7 6.5 0.075 11.2 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family DnaJ PF00226.31 EAU84840.1 - 2.6e-18 65.9 0.0 4.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain gp37_C PF12604.8 EAU84840.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Tail fibre protein gp37 C terminal RdRP PF05183.12 EAU84841.2 - 3.9e-123 412.2 0.0 5e-123 411.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Clat_adaptor_s PF01217.20 EAU84842.2 - 2.1e-56 189.8 1.3 2.4e-56 189.6 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF262 PF03235.14 EAU84845.2 - 4.2e-15 56.5 1.5 6.1e-15 56.0 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function DUF262 PBP1_TM PF14812.6 EAU84845.2 - 0.53 10.7 7.1 2.1 8.7 2.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SR-25 PF10500.9 EAU84846.2 - 0.31 10.6 4.3 16 5.0 2.8 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TspO_MBR PF03073.15 EAU84847.1 - 5.8e-42 143.0 8.1 6.7e-42 142.8 8.1 1.0 1 0 0 1 1 1 1 TspO/MBR family Histidinol_dh PF00815.20 EAU84848.1 - 1.9e-164 547.5 1.1 3.4e-164 546.7 1.1 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EAU84848.1 - 3.7e-25 87.5 0.2 8.1e-25 86.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EAU84848.1 - 1.9e-10 41.0 2.1 2.8e-10 40.5 0.2 2.3 3 0 0 3 3 3 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG-like PF12643.7 EAU84848.1 - 0.023 15.0 0.2 0.048 13.9 0.2 1.5 1 0 0 1 1 1 0 MazG-like family NAD_binding_5 PF07994.12 EAU84848.1 - 0.035 13.5 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Transket_pyr PF02779.24 EAU84849.1 - 1.5e-48 164.9 0.0 3.1e-48 163.8 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAU84849.1 - 4.2e-41 139.7 0.1 8e-41 138.8 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EAU84849.1 - 0.016 15.5 0.1 0.036 14.4 0.1 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF3343 PF11823.8 EAU84849.1 - 0.11 11.9 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) adh_short PF00106.25 EAU84850.2 - 7.7e-42 143.0 0.0 1e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU84850.2 - 1.9e-32 112.7 0.0 2.3e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU84850.2 - 1.8e-15 57.3 0.6 2.2e-14 53.8 0.6 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU84850.2 - 4.8e-06 26.2 0.1 0.00014 21.4 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAU84850.2 - 5.5e-05 23.1 0.0 0.0003 20.7 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EAU84850.2 - 0.0012 17.9 0.2 0.0026 16.8 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EAU84850.2 - 0.0022 17.6 0.1 0.51 9.9 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 EAU84850.2 - 0.018 14.5 0.0 0.08 12.3 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Amidohydro_2 PF04909.14 EAU84851.1 - 2.1e-33 116.4 0.0 2.8e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Chlorophyllase2 PF12740.7 EAU84852.2 - 0.073 12.0 0.1 0.15 11.0 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Iso_dh PF00180.20 EAU84853.2 - 3.9e-81 272.9 0.1 4.9e-81 272.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Piwi PF02171.17 EAU84854.2 - 3.1e-57 194.1 0.0 9.6e-43 146.5 0.0 2.2 2 0 0 2 2 2 2 Piwi domain ArgoN PF16486.5 EAU84854.2 - 1.5e-21 77.4 0.0 4.9e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EAU84854.2 - 2.8e-16 58.9 0.8 5.5e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EAU84854.2 - 1.8e-13 50.6 0.0 5e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EAU84854.2 - 3.1e-09 37.0 0.3 1.5e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Mid domain of argonaute SNARE_assoc PF09335.11 EAU84857.2 - 4.8e-17 62.5 2.0 4.8e-17 62.5 2.0 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein Ribosomal_L36e PF01158.18 EAU84858.1 - 2.2e-39 133.6 4.3 2.5e-39 133.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 EAU84858.1 - 0.023 14.3 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CK_II_beta PF01214.18 EAU84859.2 - 1.9e-76 255.9 0.0 2.5e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.13 EAU84859.2 - 1.8e-05 25.0 6.0 2.4e-05 24.6 6.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein SDA1 PF05285.12 EAU84859.2 - 0.076 12.4 9.7 0.11 11.9 9.7 1.1 1 0 0 1 1 1 0 SDA1 DUF5102 PF17104.5 EAU84859.2 - 0.21 11.6 6.5 0.31 11.0 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5102) BUD22 PF09073.10 EAU84859.2 - 0.26 10.6 7.5 0.34 10.2 7.5 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EAU84859.2 - 0.38 9.0 5.2 0.5 8.6 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 EAU84859.2 - 0.94 9.8 13.0 2 8.7 13.0 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Nop14 PF04147.12 EAU84859.2 - 0.96 7.6 11.2 1.2 7.2 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4637 PF15470.6 EAU84859.2 - 4.2 7.1 13.2 12 5.5 10.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Roughex PF06020.11 EAU84859.2 - 6 5.9 7.8 8.9 5.3 7.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CRCB PF02537.15 EAU84860.2 - 2.8e-32 110.9 18.8 2.2e-18 66.3 6.6 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Snapin_Pallidin PF14712.6 EAU84861.2 - 0.046 14.1 0.3 0.07 13.6 0.3 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Globin PF00042.22 EAU84862.2 - 0.0031 18.1 0.0 0.0064 17.0 0.0 1.5 1 0 0 1 1 1 1 Globin DUF2608 PF11019.8 EAU84862.2 - 0.0088 15.6 0.0 2.8 7.4 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2608) Hydrolase PF00702.26 EAU84862.2 - 0.016 15.5 0.0 0.65 10.2 0.0 2.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L6e PF01159.19 EAU84863.1 - 2e-39 134.5 0.1 3.9e-39 133.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 EAU84863.1 - 2.9e-05 24.2 2.3 3e-05 24.2 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain 60KD_IMP PF02096.20 EAU84864.2 - 1.8e-13 50.7 1.3 3.8e-12 46.4 1.3 2.0 1 1 0 1 1 1 1 60Kd inner membrane protein Histone PF00125.24 EAU84865.2 - 4.1e-44 150.1 0.6 6.9e-44 149.4 0.6 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAU84865.2 - 0.0024 18.0 0.1 0.0037 17.4 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EAU84865.2 - 0.014 15.8 0.2 0.023 15.1 0.2 1.4 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 EAU84865.2 - 0.017 15.2 0.1 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EAU84865.2 - 0.019 15.3 0.6 0.051 13.9 0.6 1.8 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2833 PF11090.8 EAU84866.2 - 0.037 14.4 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Nrap_D6 PF17407.2 EAU84866.2 - 0.038 14.2 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 Nrap protein domain 6 TRAM_LAG1_CLN8 PF03798.16 EAU84867.2 - 7.4e-34 117.2 27.9 7.4e-34 117.2 27.9 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EAU84867.2 - 2.1e-15 56.1 0.1 2.1e-15 56.1 0.1 2.4 2 0 0 2 2 2 1 TRAM1-like protein TctB PF07331.11 EAU84867.2 - 4.6 7.5 8.0 1.3 9.3 2.0 2.7 3 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family EloA-BP1 PF15870.5 EAU84868.2 - 9e-06 26.0 0.4 3.3e-05 24.2 0.3 1.8 1 1 1 2 2 2 1 ElonginA binding-protein 1 RNase_T PF00929.24 EAU84868.2 - 1.1e-05 26.0 0.0 2.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.12 EAU84868.2 - 0.00062 20.4 3.3 0.0014 19.3 3.3 1.6 1 0 0 1 1 1 1 CHORD BBS1 PF14779.6 EAU84868.2 - 0.11 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 UPF0183 PF03676.14 EAU84869.1 - 1.1e-55 189.6 0.0 1.8e-55 188.8 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) DNA_pol_E_B PF04042.16 EAU84870.2 - 2.3e-46 157.8 0.6 2.3e-46 157.8 0.6 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EAU84870.2 - 0.00016 21.8 0.1 0.00044 20.4 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain Gly_transf_sug PF04488.15 EAU84871.2 - 1.3e-22 80.3 0.0 2.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EAU84871.2 - 0.073 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EAU84871.2 - 0.44 9.8 1.0 0.61 9.3 0.3 1.4 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Sensor PF13796.6 EAU84871.2 - 2.9 7.9 6.8 0.45 10.6 0.5 2.3 2 0 0 2 2 2 0 Putative sensor MFS_1 PF07690.16 EAU84872.2 - 2.7e-32 112.1 13.1 5.5e-32 111.1 12.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU84872.2 - 8.3e-06 24.9 4.0 1.7e-05 23.9 4.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 EAU84872.2 - 0.00042 19.4 0.9 0.0016 17.4 0.1 2.1 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM TruD PF01142.18 EAU84873.1 - 8.8e-76 255.4 0.2 1.1e-66 225.4 0.2 3.3 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) FoP_duplication PF13865.6 EAU84873.1 - 0.51 10.9 24.7 1.2 9.7 9.4 4.1 4 0 0 4 4 4 0 C-terminal duplication domain of Friend of PRMT1 GRP PF07172.11 EAU84873.1 - 6.3 7.6 14.5 2.7 8.7 0.9 2.7 2 0 0 2 2 2 0 Glycine rich protein family OMPdecase PF00215.24 EAU84874.2 - 1.3e-70 237.5 0.0 1.6e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ribosomal_L6 PF00347.23 EAU84876.1 - 3.3e-27 95.0 5.2 1.3e-16 61.1 1.9 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ICMT PF04140.14 EAU84877.1 - 8.4e-26 90.2 1.4 1.5e-25 89.4 1.4 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAU84877.1 - 4.5e-11 43.1 1.9 4.5e-11 43.1 1.9 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 EAU84877.1 - 1.1e-05 25.0 3.9 1.1e-05 25.0 3.9 1.7 2 0 0 2 2 2 1 NnrU protein GTP_EFTU PF00009.27 EAU84878.2 - 1.4e-46 158.5 0.0 2.2e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAU84878.2 - 2.5e-15 56.3 0.0 1.9e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.6 EAU84878.2 - 6.6e-12 45.4 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EAU84878.2 - 2.6e-05 24.3 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EAU84878.2 - 0.00077 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EAU84878.2 - 0.12 11.8 0.0 0.42 10.0 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ADH_N PF08240.12 EAU84880.1 - 1.6e-30 105.1 0.1 2.9e-30 104.3 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU84880.1 - 4.2e-22 78.5 0.0 6.6e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU84880.1 - 3.3e-07 31.4 0.2 1.4e-06 29.4 0.2 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAU84880.1 - 1e-06 28.4 0.7 0.0014 18.2 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus Methyltransf_25 PF13649.6 EAU84880.1 - 0.00098 19.8 0.0 0.0016 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 EAU84880.1 - 0.017 14.4 0.3 0.028 13.7 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EAU84880.1 - 0.026 14.1 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.12 EAU84880.1 - 0.063 13.9 0.0 0.15 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EAU84880.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PrmA PF06325.13 EAU84880.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.25 EAU84881.2 - 1e-43 149.6 0.0 1.3e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU84881.2 - 3.1e-21 75.8 0.0 4.2e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU84881.2 - 0.00036 19.9 0.0 0.00049 19.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAU84881.2 - 0.0052 16.2 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAU84881.2 - 0.058 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Meth_synt_2 PF01717.18 EAU84882.1 - 1.8e-149 497.4 0.0 1.8e-145 484.3 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EAU84882.1 - 5.8e-115 384.1 0.0 9.7e-109 363.7 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF863 PF05904.11 EAU84882.1 - 0.034 12.6 0.1 0.049 12.1 0.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) ETF PF01012.21 EAU84882.1 - 0.56 10.1 4.6 4.6 7.1 1.7 2.6 1 1 1 2 2 2 0 Electron transfer flavoprotein domain eRF1_1 PF03463.15 EAU84885.2 - 1.5e-49 167.3 0.0 2.2e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EAU84885.2 - 8.7e-22 77.7 0.0 1.5e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EAU84885.2 - 8.5e-19 68.2 0.0 1.4e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Phosducin PF02114.16 EAU84886.1 - 0.0026 16.8 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EAU84886.1 - 0.0029 17.6 0.1 0.0049 16.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Mob1_phocein PF03637.17 EAU84886.1 - 0.025 14.6 0.6 0.037 14.1 0.6 1.2 1 0 0 1 1 1 0 Mob1/phocein family SLS PF14611.6 EAU84886.1 - 0.08 12.8 0.3 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator PGA2 PF07543.12 EAU84886.1 - 0.44 10.5 4.3 0.16 12.0 1.0 1.7 2 0 0 2 2 2 0 Protein trafficking PGA2 Glyco_hydro_18 PF00704.28 EAU84887.2 - 1.2e-47 163.2 0.0 1.9e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Wtap PF17098.5 EAU84889.1 - 1.5e-13 50.9 9.0 1.1e-11 44.9 9.0 2.2 1 1 0 1 1 1 1 WTAP/Mum2p family PKcGMP_CC PF16808.5 EAU84889.1 - 0.057 13.3 3.2 6.7 6.7 1.9 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ank_2 PF12796.7 EAU84890.2 - 2.6e-11 43.9 0.0 0.00014 22.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU84890.2 - 6.3e-09 36.2 0.1 0.0039 17.7 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU84890.2 - 6.7e-07 29.5 0.1 2.4e-05 24.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU84890.2 - 1.8e-05 24.7 0.1 0.0099 16.3 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EAU84890.2 - 3.3e-05 24.1 0.0 0.00042 20.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat MFS_1 PF07690.16 EAU84891.2 - 3.5e-13 49.2 13.6 2.5e-07 29.9 0.1 3.3 1 1 2 4 4 4 4 Major Facilitator Superfamily MFS_2 PF13347.6 EAU84891.2 - 1.7e-11 43.3 4.2 4e-09 35.5 1.6 3.7 4 1 0 4 4 4 2 MFS/sugar transport protein DCX PF03607.17 EAU84891.2 - 0.097 12.8 0.0 13 6.0 0.0 3.0 3 0 0 3 3 3 0 Doublecortin Diphthami_syn_2 PF01902.17 EAU84892.2 - 1.5e-32 112.9 0.0 4.3e-30 104.9 0.0 2.4 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EAU84892.2 - 2.9e-15 56.3 0.0 5.9e-08 32.8 0.0 3.3 3 1 0 3 3 3 2 Endoribonuclease L-PSP tRNA_synthFbeta PF17759.1 EAU84893.2 - 5e-47 160.1 0.0 7.2e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EAU84893.2 - 8.4e-35 118.9 0.2 3.2e-32 110.6 0.1 2.5 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EAU84893.2 - 5.6e-27 94.5 0.0 1e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EAU84893.2 - 4.1e-20 71.8 0.0 3.8e-17 62.3 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain Endonuc-dimeris PF09124.10 EAU84893.2 - 0.13 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation tRNA-synt_2d PF01409.20 EAU84893.2 - 0.14 11.7 0.0 0.43 10.0 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) ThrE PF06738.12 EAU84897.2 - 2.2e-38 132.0 1.0 2.2e-38 132.0 1.0 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EAU84897.2 - 3.1e-05 24.1 7.2 3.1e-05 24.1 7.2 2.6 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE tRNA-synt_2d PF01409.20 EAU84898.2 - 2.4e-84 282.7 0.0 6.1e-55 186.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EAU84898.2 - 6.8e-18 64.7 0.8 3e-17 62.6 0.3 2.3 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EAU84898.2 - 2.7e-10 40.1 0.0 2.4e-05 23.9 0.0 2.6 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EAU84898.2 - 0.0021 17.2 0.3 0.025 13.6 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EAU84898.2 - 0.0023 17.9 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 EAU84898.2 - 0.0095 15.9 1.3 0.033 14.2 1.3 2.0 1 1 0 1 1 1 1 PheRS DNA binding domain 2 PheRS_DBD1 PF18552.1 EAU84898.2 - 0.027 14.2 0.2 0.15 11.8 0.2 2.2 1 1 0 1 1 1 0 PheRS DNA binding domain 1 Pex2_Pex12 PF04757.14 EAU84899.2 - 5.8e-36 124.2 7.7 8.1e-36 123.7 7.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 EAU84899.2 - 0.00014 21.7 2.6 0.00014 21.7 2.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU84899.2 - 0.0018 18.2 4.2 0.008 16.2 4.2 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAU84899.2 - 0.0025 17.7 3.8 0.01 15.7 3.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU84899.2 - 0.0035 17.1 0.5 0.0035 17.1 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU84899.2 - 0.009 16.1 3.9 0.03 14.5 3.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EAU84899.2 - 0.05 13.9 7.1 0.11 12.9 3.3 2.4 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 EAU84899.2 - 0.79 9.6 4.2 0.33 10.8 1.1 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EAU84899.2 - 2.8 8.3 6.5 23 5.4 6.5 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger domain IBN_N PF03810.19 EAU84900.2 - 0.00012 21.9 0.0 0.0028 17.5 0.2 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF1877 PF08974.10 EAU84900.2 - 0.1 12.7 0.0 1.6 8.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1877) ERbeta_N PF12497.8 EAU84900.2 - 0.15 11.9 0.2 7.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Estrogen receptor beta Slx4 PF09494.10 EAU84901.1 - 1.8e-08 34.2 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Mur_ligase_M PF08245.12 EAU84902.2 - 5.1e-08 33.1 0.1 4.2e-05 23.6 0.0 2.7 1 1 1 2 2 2 2 Mur ligase middle domain BRCT_2 PF16589.5 EAU84903.2 - 7.6e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EAU84903.2 - 2.5e-09 37.4 0.0 4.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EAU84903.2 - 0.00031 20.6 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Sec63 PF02889.16 EAU84905.2 - 1.4e-63 214.5 0.4 2.1e-63 213.9 0.4 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EAU84905.2 - 3.6e-36 124.6 0.1 5.5e-26 91.4 0.2 4.0 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EAU84905.2 - 4.4e-15 56.1 0.0 2.2e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAU84905.2 - 1.4e-08 34.7 0.0 0.00058 19.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 EAU84905.2 - 4.1e-07 30.4 0.2 0.015 15.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain Helicase_C PF00271.31 EAU84905.2 - 7.3e-07 29.5 0.1 6.7e-05 23.2 0.0 4.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAU84905.2 - 1.3e-06 28.7 0.3 0.036 14.4 0.3 3.2 2 1 0 2 2 2 2 AAA domain Helicase_RecD PF05127.14 EAU84905.2 - 3e-05 24.0 0.0 0.0039 17.1 0.0 2.8 3 0 0 3 3 2 1 Helicase AAA_11 PF13086.6 EAU84905.2 - 0.0018 18.1 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Helicase_PWI PF18149.1 EAU84905.2 - 0.0037 17.4 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_16 PF13191.6 EAU84905.2 - 0.0042 17.5 0.0 6.1 7.2 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 EAU84905.2 - 0.0076 15.3 0.1 4.3 6.3 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_25 PF13481.6 EAU84905.2 - 0.012 15.2 0.1 1.8 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAU84905.2 - 0.015 15.4 0.0 0.091 12.8 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 EAU84905.2 - 0.043 13.3 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EAU84905.2 - 0.058 13.1 0.3 17 5.1 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EAU84905.2 - 0.083 12.2 1.8 0.25 10.7 0.0 2.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 EAU84905.2 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Aminotran_1_2 PF00155.21 EAU84906.2 - 3.8e-61 207.3 0.0 4.2e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EAU84906.2 - 3.4e-06 26.6 0.0 6.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EAU84906.2 - 2.2e-05 23.2 0.1 7.5e-05 21.4 0.1 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EAU84906.2 - 0.00014 21.3 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EAU84906.2 - 0.005 15.8 0.0 0.083 11.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V NAD_binding_6 PF08030.12 EAU84907.2 - 4.3e-19 69.2 0.0 7e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAU84907.2 - 4.3e-18 65.4 0.0 1.6e-17 63.5 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EAU84907.2 - 8e-16 58.3 9.0 8e-16 58.3 9.0 2.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Ank_5 PF13857.6 EAU84908.2 - 3.1e-28 97.5 0.5 1.1e-08 35.2 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU84908.2 - 4.9e-27 94.0 0.6 3e-11 43.6 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAU84908.2 - 1.2e-26 93.1 0.0 2.1e-10 41.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU84908.2 - 2.5e-21 73.5 1.1 0.00017 21.8 0.0 5.3 5 0 0 5 5 4 4 Ankyrin repeat FYVE PF01363.21 EAU84908.2 - 2.9e-20 72.1 9.7 2.9e-20 72.1 9.7 2.0 2 0 0 2 2 1 1 FYVE zinc finger Ank PF00023.30 EAU84908.2 - 2e-18 65.9 0.6 0.0022 18.4 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat zf-RING_2 PF13639.6 EAU84908.2 - 6e-08 32.9 4.0 6e-08 32.9 4.0 3.8 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU84908.2 - 1.6e-05 24.6 3.0 1.6e-05 24.6 3.0 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU84908.2 - 0.00076 19.7 2.4 0.00076 19.7 2.4 2.4 3 0 0 3 3 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAU84908.2 - 0.004 16.9 4.9 0.004 16.9 4.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger DUF1843 PF08898.10 EAU84908.2 - 0.065 13.7 0.2 0.27 11.8 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) FANCL_C PF11793.8 EAU84908.2 - 0.075 13.2 6.7 0.04 14.1 3.2 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain FYVE_2 PF02318.16 EAU84908.2 - 3 8.1 10.4 0.16 12.2 3.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.6 EAU84908.2 - 4.6 7.3 25.8 2.6 8.1 4.8 3.3 3 0 0 3 3 3 0 zinc-RING finger domain HAUS4 PF14735.6 EAU84909.1 - 0.014 15.2 1.2 0.018 14.7 1.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF2870 PF11069.8 EAU84909.1 - 0.062 13.7 0.8 0.14 12.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Cwf_Cwc_15 PF04889.12 EAU84909.1 - 0.12 12.0 9.2 0.18 11.5 9.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF3g PF12353.8 EAU84909.1 - 0.16 12.3 0.5 0.27 11.6 0.5 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G PI31_Prot_N PF11566.8 EAU84910.1 - 1.1e-44 152.1 0.1 1.4e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EAU84910.1 - 4.3e-11 43.8 21.4 4.3e-11 43.8 21.4 2.4 2 1 0 2 2 2 1 PI31 proteasome regulator DEAD PF00270.29 EAU84911.2 - 1.7e-52 177.8 0.0 1.1e-51 175.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU84911.2 - 4.7e-26 91.3 0.0 3.5e-25 88.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU84911.2 - 0.00061 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CP12 PF02672.15 EAU84911.2 - 2.1 9.2 5.5 0.84 10.4 1.4 2.6 2 0 0 2 2 2 0 CP12 domain Nsp1_C PF05064.13 EAU84912.1 - 5.4e-30 103.6 1.0 8.9e-30 102.9 0.1 1.7 3 0 0 3 3 3 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EAU84912.1 - 6.3e-15 55.8 100.5 8e-08 33.0 28.8 4.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region Lebercilin PF15619.6 EAU84912.1 - 0.046 13.4 0.5 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PspA_IM30 PF04012.12 EAU84912.1 - 0.26 10.8 3.3 8 6.0 0.9 2.2 2 0 0 2 2 2 0 PspA/IM30 family Baculo_PEP_C PF04513.12 EAU84912.1 - 0.39 10.8 5.8 1.2 9.2 0.6 2.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dor1 PF04124.12 EAU84912.1 - 1.8 7.2 4.7 10 4.7 4.7 1.9 1 1 0 1 1 1 0 Dor1-like family NPV_P10 PF05531.12 EAU84912.1 - 2.1 8.9 3.9 74 3.9 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EAU84912.1 - 3.3 7.8 4.8 5.2 7.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 EAU84912.1 - 4.5 7.8 5.6 14 6.2 1.1 2.4 2 1 0 2 2 2 0 Snapin/Pallidin AAA_22 PF13401.6 EAU84914.2 - 0.00055 20.2 0.8 0.61 10.3 0.8 2.8 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 EAU84914.2 - 0.0066 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_10 PF12846.7 EAU84914.2 - 0.051 12.5 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.9 EAU84914.2 - 0.088 12.0 0.1 0.76 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EAU84914.2 - 0.092 12.0 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EAU84914.2 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Methyltransf_8 PF05148.15 EAU84915.1 - 4.1e-67 226.3 0.0 8.4e-67 225.2 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EAU84915.1 - 1.3e-06 29.0 0.0 4.4e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU84915.1 - 0.00047 20.8 0.1 0.0019 18.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU84915.1 - 0.0045 16.8 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU84915.1 - 0.31 11.8 1.5 1.1 10.1 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Peptidase_S64 PF08192.11 EAU84915.1 - 0.56 8.6 7.1 0.7 8.3 7.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 EAU84915.1 - 2.4 6.6 15.0 3 6.3 15.0 1.1 1 0 0 1 1 1 0 Macoilin family Methyltransf_32 PF13679.6 EAU84915.1 - 4.4 7.3 0.0 4.4 7.3 0.0 2.8 2 1 0 2 2 1 0 Methyltransferase domain PAT1 PF09770.9 EAU84915.1 - 4.6 5.4 13.9 5.9 5.0 13.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 EAU84915.1 - 5.4 5.6 13.1 8.6 4.9 13.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLX9 PF15341.6 EAU84915.1 - 7.1 7.0 28.1 0.49 10.8 17.2 2.4 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 UPRTase PF14681.6 EAU84916.2 - 1.3e-67 227.3 0.0 1.5e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EAU84916.2 - 0.0038 16.8 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_1 PF00667.20 EAU84917.2 - 1.4e-53 181.7 0.0 2.2e-53 181.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EAU84917.2 - 5e-08 33.6 0.0 1.6e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 EAU84917.2 - 7.8e-05 22.8 0.0 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 EAU84917.2 - 0.0008 19.7 0.2 0.0051 17.1 0.1 2.2 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 EAU84917.2 - 0.041 14.2 0.0 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.19 EAU84918.1 - 2e-109 366.7 11.4 2.4e-109 366.5 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Dicer_dimer PF03368.14 EAU84918.1 - 0.0088 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain GFO_IDH_MocA PF01408.22 EAU84919.1 - 6e-21 75.5 0.0 1e-20 74.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAU84919.1 - 2.6e-08 33.9 0.0 4.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EAU84919.1 - 0.0029 18.2 0.0 0.0052 17.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ubiquitin PF00240.23 EAU84920.2 - 7.2e-07 28.9 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EAU84920.2 - 0.051 14.1 0.0 0.16 12.6 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Trp_oprn_chp PF09534.10 EAU84920.2 - 0.066 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) cNMP_binding PF00027.29 EAU84921.1 - 1.8e-32 111.2 0.8 1.9e-14 53.4 0.1 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EAU84921.1 - 9.3e-10 38.0 0.2 2.5e-09 36.6 0.2 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Mid2 PF04478.12 EAU84922.2 - 0.036 13.9 0.4 0.071 13.0 0.4 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EAU84922.2 - 0.063 13.2 10.5 62 3.5 10.5 2.5 1 1 0 1 1 1 0 TMEM154 protein family LapA_dom PF06305.11 EAU84922.2 - 0.088 12.6 1.3 0.17 11.7 1.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Amnionless PF14828.6 EAU84922.2 - 0.099 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless MFS_1 PF07690.16 EAU84922.2 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Adipogenin PF15202.6 EAU84922.2 - 0.15 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Adipogenin DUF5305 PF17231.2 EAU84922.2 - 0.18 11.2 0.7 0.24 10.8 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Syndecan PF01034.20 EAU84922.2 - 0.23 11.4 0.4 0.46 10.4 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain Ytp1 PF10355.9 EAU84923.1 - 2.7e-109 364.7 5.1 3.7e-109 364.2 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EAU84923.1 - 4.6e-15 55.3 0.3 4.6e-15 55.3 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) PGPGW PF09656.10 EAU84923.1 - 0.049 13.1 0.2 0.049 13.1 0.2 2.5 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) Frag1 PF10277.9 EAU84923.1 - 4.7 6.7 10.3 4.2 6.9 0.0 3.1 2 1 1 3 3 3 0 Frag1/DRAM/Sfk1 family MbeD_MobD PF04899.12 EAU84925.2 - 0.026 14.6 1.9 0.48 10.6 0.2 2.5 1 1 1 2 2 2 0 MbeD/MobD like Wtap PF17098.5 EAU84926.2 - 0.029 14.3 2.5 0.058 13.3 2.5 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family Tmemb_cc2 PF10267.9 EAU84926.2 - 0.059 12.5 0.1 0.084 12.0 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Spc24 PF08286.11 EAU84926.2 - 0.099 12.9 0.3 0.21 11.9 0.3 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 HAUS-augmin3 PF14932.6 EAU84926.2 - 0.1 12.2 2.5 0.16 11.5 1.3 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 EAU84926.2 - 0.12 11.7 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GP20 PF06810.11 EAU84926.2 - 0.15 11.8 4.0 0.59 9.9 1.7 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 FlxA PF14282.6 EAU84926.2 - 0.41 10.7 5.2 0.83 9.7 5.2 1.4 1 0 0 1 1 1 0 FlxA-like protein AAA_23 PF13476.6 EAU84926.2 - 0.7 10.3 3.6 0.81 10.1 2.2 1.7 2 0 0 2 2 2 0 AAA domain CDT1_C PF16679.5 EAU84927.1 - 6.1e-14 52.2 0.4 2e-13 50.6 0.4 2.0 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Nup160 PF11715.8 EAU84928.1 - 2.5e-37 128.7 0.0 6.8e-37 127.3 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 TPR_19 PF14559.6 EAU84928.1 - 0.048 14.2 5.2 1.1 9.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU84928.1 - 0.12 12.5 1.4 0.88 9.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU84928.1 - 0.14 12.4 6.8 8 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU84928.1 - 0.41 10.6 1.8 29 4.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU84928.1 - 3.5 8.0 5.2 12 6.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAU84928.1 - 3.5 8.4 10.0 0.44 11.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EAU84929.1 - 2.4e-13 49.7 1.1 4.9e-13 48.7 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU84929.1 - 3.1e-05 24.0 9.2 5.9e-05 23.1 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 EAU84930.1 - 3.7e-44 146.8 25.0 2.3e-07 30.3 0.2 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 EAU84930.1 - 4.6e-38 126.3 35.0 0.00013 21.8 0.2 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat STI1 PF17830.1 EAU84930.1 - 5.1e-38 128.8 17.7 6.9e-20 70.7 5.0 3.4 4 0 0 4 4 3 2 STI1 domain TPR_11 PF13414.6 EAU84930.1 - 7.3e-24 83.2 23.4 9e-07 28.5 0.7 8.8 7 2 2 9 9 9 6 TPR repeat TPR_16 PF13432.6 EAU84930.1 - 7.2e-22 77.8 14.8 7.2e-06 26.6 0.1 6.7 4 2 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EAU84930.1 - 1.6e-21 74.6 29.6 0.00099 19.1 0.1 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EAU84930.1 - 3e-19 68.0 14.3 0.016 16.0 0.1 9.0 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EAU84930.1 - 8.2e-19 67.9 20.7 1.8e-07 31.5 0.0 8.2 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAU84930.1 - 2.7e-18 66.0 20.3 2.8e-09 37.1 0.1 7.7 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAU84930.1 - 7.6e-16 57.3 2.2 0.0067 16.7 0.0 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAU84930.1 - 1e-15 56.5 14.3 0.00054 19.8 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAU84930.1 - 1.2e-14 54.1 4.8 0.029 14.5 0.1 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 EAU84930.1 - 4.1e-10 39.2 17.8 0.13 12.2 0.0 9.3 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAU84930.1 - 4.9e-08 33.1 23.7 0.33 11.7 0.1 9.0 10 0 0 10 10 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU84930.1 - 3.3e-06 27.2 4.6 0.036 14.3 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EAU84930.1 - 0.00026 20.9 14.6 0.67 10.0 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EAU84930.1 - 0.001 19.3 10.0 8.8 6.7 0.0 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF357 PF04010.13 EAU84930.1 - 0.012 15.7 2.3 0.028 14.5 0.1 2.9 2 2 1 3 3 2 0 Protein of unknown function (DUF357) DUF5113 PF17140.4 EAU84930.1 - 0.018 14.8 3.7 26 4.6 0.1 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF5113) Alkyl_sulf_dimr PF14863.6 EAU84930.1 - 0.025 15.0 10.3 6.5 7.2 0.0 4.4 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation PPR PF01535.20 EAU84930.1 - 0.031 14.5 3.6 26 5.3 0.1 4.6 4 0 0 4 4 4 0 PPR repeat SRP_TPR_like PF17004.5 EAU84930.1 - 0.036 14.1 0.5 0.036 14.1 0.5 3.0 3 1 1 4 4 4 0 Putative TPR-like repeat BTAD PF03704.17 EAU84930.1 - 0.063 13.7 17.3 0.36 11.2 0.2 5.0 5 1 1 6 6 5 0 Bacterial transcriptional activator domain XPC-binding PF09280.11 EAU84930.1 - 0.083 12.6 13.5 0.88 9.4 2.7 2.7 2 0 0 2 2 2 0 XPC-binding domain SHNi-TPR PF10516.9 EAU84930.1 - 0.36 10.3 3.3 9.3 5.8 0.1 4.2 6 0 0 6 6 5 0 SHNi-TPR BNIP3 PF06553.12 EAU84930.1 - 0.63 9.7 3.8 1.8 8.2 3.8 1.7 1 0 0 1 1 1 0 BNIP3 SPO22 PF08631.10 EAU84930.1 - 3.6 7.0 8.3 9.5 5.6 0.0 4.0 4 1 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like DUF4200 PF13863.6 EAU84932.1 - 0.015 15.7 28.3 0.015 15.7 28.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) COG6 PF06419.11 EAU84932.1 - 0.3 9.3 16.5 0.15 10.2 14.6 1.3 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 DDE_Tnp_IS66 PF03050.14 EAU84932.1 - 0.5 9.8 13.5 0.65 9.4 13.5 1.1 1 0 0 1 1 1 0 Transposase IS66 family UPF0565 PF10561.9 EAU84932.1 - 2.2 7.4 10.0 2.9 7.0 10.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 APG6_N PF17675.1 EAU84932.1 - 3 8.4 29.1 4.2 7.9 28.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EAU84932.1 - 3.3 7.2 16.0 4.8 6.6 16.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 EAU84932.1 - 4.2 5.9 18.2 5 5.6 18.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Borrelia_P83 PF05262.11 EAU84932.1 - 5.7 5.3 29.3 7 5.0 29.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein HSP70 PF00012.20 EAU84932.1 - 7.5 4.6 21.7 9.4 4.3 21.7 1.1 1 0 0 1 1 1 0 Hsp70 protein Isochorismatase PF00857.20 EAU84933.2 - 8.7e-11 42.3 0.5 2.5e-08 34.3 0.5 2.6 1 1 0 1 1 1 1 Isochorismatase family AAA_13 PF13166.6 EAU84934.2 - 0.0058 15.3 5.3 0.0092 14.7 5.3 1.2 1 0 0 1 1 1 1 AAA domain STAT_alpha PF01017.20 EAU84934.2 - 0.011 15.6 5.2 0.024 14.6 5.2 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain AAA_23 PF13476.6 EAU84934.2 - 0.016 15.8 2.3 0.036 14.6 2.3 1.6 1 0 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.9 EAU84934.2 - 0.063 12.1 1.6 0.12 11.2 1.6 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 EAU84934.2 - 0.13 11.6 14.8 0.26 10.6 14.8 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EAU84934.2 - 0.17 10.7 16.0 0.34 9.8 16.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EAU84934.2 - 0.37 11.0 6.9 0.59 10.3 4.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EAU84934.2 - 0.69 9.9 25.8 0.62 10.1 0.2 2.7 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mto2_bdg PF12808.7 EAU84934.2 - 0.73 10.2 9.8 0.32 11.3 0.3 3.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region V_ATPase_I PF01496.19 EAU84934.2 - 0.79 7.6 2.4 1.2 7.0 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 EAU84934.2 - 1.1 9.4 16.9 7.7 6.6 12.5 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Phage_GP20 PF06810.11 EAU84934.2 - 1.1 9.0 15.8 1.1 9.1 11.7 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 EAU84934.2 - 1.4 9.4 4.8 5.6 7.5 4.8 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Ax_dynein_light PF10211.9 EAU84934.2 - 1.4 8.8 15.9 9.9 6.1 0.1 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain BRE1 PF08647.11 EAU84934.2 - 2.1 8.5 15.6 0.49 10.5 11.9 1.9 2 1 0 2 2 1 0 BRE1 E3 ubiquitin ligase DUF4200 PF13863.6 EAU84934.2 - 2.5 8.5 17.8 2.9 8.3 15.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) IFT20 PF14931.6 EAU84934.2 - 2.8 8.1 12.1 0.12 12.6 4.4 2.3 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF3450 PF11932.8 EAU84934.2 - 3.9 6.7 12.7 4.9 6.4 10.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 EAU84934.2 - 6.2 6.1 7.5 12 5.2 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) B12D PF06522.11 EAU84935.1 - 1.7e-13 50.1 0.1 2.2e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.21 EAU84936.2 - 5.7e-40 137.3 0.0 7.2e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family A_deamin PF02137.18 EAU84936.2 - 8.2e-18 64.9 0.0 1.1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2838 PF10998.8 EAU84937.1 - 3.3e-43 146.4 11.0 8.4e-43 145.1 11.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Cep57_CLD_2 PF14197.6 EAU84937.1 - 1 9.5 3.3 19 5.4 0.6 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Exo84_C PF16528.5 EAU84937.1 - 2.6 7.8 6.2 1.4 8.7 1.9 2.4 3 0 0 3 3 3 0 Exocyst component 84 C-terminal DUF1748 PF08520.10 EAU84938.2 - 4.7e-26 90.5 0.0 5.4e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DAD PF02109.16 EAU84939.1 - 8.8e-47 157.9 1.1 1.1e-46 157.7 1.1 1.0 1 0 0 1 1 1 1 DAD family Sod_Fe_C PF02777.18 EAU84940.1 - 9.2e-15 54.7 0.0 1.3e-06 28.5 0.0 2.5 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Hexokinase_2 PF03727.16 EAU84941.1 - 1.9e-78 263.2 0.0 3.5e-78 262.4 0.0 1.4 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EAU84941.1 - 5.9e-72 241.7 0.0 8.2e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Mt_ATP-synt_D PF05873.12 EAU84942.1 - 4.9e-17 62.2 3.8 5.9e-17 61.9 3.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) OmpH PF03938.14 EAU84942.1 - 0.006 16.9 3.0 0.068 13.5 2.7 2.0 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Phage_GP20 PF06810.11 EAU84942.1 - 0.03 14.1 4.0 0.053 13.3 3.9 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF3074 PF11274.8 EAU84942.1 - 0.04 13.9 0.4 0.051 13.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) RPW8 PF05659.11 EAU84942.1 - 0.11 12.2 1.4 0.76 9.5 0.8 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2408 PF10303.9 EAU84942.1 - 0.17 12.4 1.2 0.42 11.2 0.7 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) Aft1_HRA PF11786.8 EAU84943.1 - 2.8e-28 98.1 9.2 1.3e-27 96.0 9.2 2.2 1 0 0 1 1 1 1 Aft1 HRA domain bZIP_1 PF00170.21 EAU84943.1 - 2.8e-10 40.1 9.1 6.5e-10 39.0 9.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAU84943.1 - 1.7e-06 28.0 10.2 4.4e-06 26.7 10.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper GIT_CC PF16559.5 EAU84943.1 - 0.11 12.4 1.2 0.22 11.4 1.2 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF3445 PF11927.8 EAU84944.1 - 6.4e-71 238.6 0.0 8.3e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) GDI PF00996.18 EAU84945.1 - 6.6e-39 133.6 0.0 9.6e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EAU84945.1 - 0.041 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.22 EAU84946.1 - 2.4e-40 136.2 0.0 6.1e-19 67.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU84946.1 - 5.2e-05 23.3 0.0 0.33 11.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EAU84946.1 - 0.058 13.3 0.0 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EAU84946.1 - 0.059 13.4 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ric8 PF10165.9 EAU84947.2 - 7.5e-121 404.4 0.0 8.8e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.9 EAU84948.1 - 1.1e-19 70.5 0.3 1.2e-19 70.4 0.3 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.6 EAU84948.1 - 0.0022 18.3 0.1 0.0029 17.9 0.1 1.2 1 0 0 1 1 1 1 PIN domain Cyclin_N2 PF16500.5 EAU84949.1 - 0.0094 16.7 0.2 0.02 15.6 0.2 1.4 1 0 0 1 1 1 1 N-terminal region of cyclin_N Aconitase PF00330.20 EAU84950.1 - 3.3e-163 544.0 0.0 4e-163 543.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAU84950.1 - 2.8e-39 134.4 0.0 4.6e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_hydro_125 PF06824.11 EAU84952.2 - 1.1e-147 492.3 0.1 1.2e-147 492.1 0.1 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Prenyltransf PF01255.19 EAU84956.1 - 3.2e-77 259.1 0.0 3.9e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4426 PF14467.6 EAU84956.1 - 0.026 14.5 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) HTH_17 PF12728.7 EAU84956.1 - 0.072 13.3 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain FTHFS PF01268.19 EAU84956.1 - 0.12 10.5 0.2 0.34 9.1 0.1 1.6 2 0 0 2 2 2 0 Formate--tetrahydrofolate ligase Rib PF08428.10 EAU84956.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat F-box-like PF12937.7 EAU84957.1 - 0.00039 20.3 0.2 0.0012 18.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like DUF1411 PF07199.11 EAU84957.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) F-box PF00646.33 EAU84957.1 - 0.39 10.7 2.1 2.5 8.1 2.1 2.4 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 EAU84958.1 - 1.1e-11 44.4 0.1 2.9e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84958.1 - 0.00041 20.2 0.6 0.0012 18.7 0.0 2.2 2 1 0 2 2 2 1 F-box domain Prefoldin_2 PF01920.20 EAU84958.1 - 0.032 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Prefoldin subunit DUF1192 PF06698.11 EAU84958.1 - 0.11 12.6 1.3 0.27 11.3 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) F-box-like PF12937.7 EAU84959.1 - 9.3e-13 47.9 0.4 9.3e-13 47.9 0.4 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EAU84959.1 - 6.7e-05 22.7 0.1 0.00022 21.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain Uricase PF01014.18 EAU84962.2 - 1.9e-59 199.6 3.1 3.9e-36 124.2 1.8 2.1 2 0 0 2 2 2 2 Uricase Cellulase PF00150.18 EAU84963.2 - 1.5e-20 73.8 3.4 2.6e-20 73.0 3.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Hydrophobin PF01185.18 EAU84964.1 - 4.3e-25 88.2 11.6 5.8e-25 87.7 11.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EAU84965.2 - 2.7e-24 85.6 11.6 3.9e-24 85.1 11.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin HSP33 PF01430.19 EAU84965.2 - 0.082 12.3 0.2 0.14 11.6 0.2 1.5 1 1 0 1 1 1 0 Hsp33 protein F-box-like PF12937.7 EAU84970.1 - 4.3e-09 36.1 0.4 2.2e-08 33.8 0.4 2.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84970.1 - 0.00036 20.3 0.4 0.0013 18.5 0.4 2.1 1 1 0 1 1 1 1 F-box domain Lebercilin PF15619.6 EAU84970.1 - 0.053 13.2 0.2 0.085 12.5 0.2 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF745 PF05335.13 EAU84970.1 - 0.15 11.8 0.1 0.21 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) F-box-like PF12937.7 EAU84971.1 - 2.4e-07 30.5 1.9 6e-07 29.3 0.3 2.6 2 0 0 2 2 2 1 F-box-like Sec8_exocyst PF04048.14 EAU84971.1 - 0.017 15.0 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain F-box PF00646.33 EAU84971.1 - 0.019 14.8 0.8 0.019 14.8 0.8 2.9 3 0 0 3 3 3 0 F-box domain HrpB7 PF09486.10 EAU84971.1 - 0.025 14.9 0.1 0.041 14.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Phlebovirus_NSM PF07246.11 EAU84971.1 - 0.059 12.7 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF745 PF05335.13 EAU84971.1 - 0.14 11.9 0.2 0.2 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-MYND PF01753.18 EAU84972.2 - 2.3e-07 30.8 13.6 4.5e-07 29.8 13.6 1.5 1 0 0 1 1 1 1 MYND finger DUF3824 PF12868.7 EAU84972.2 - 0.014 16.1 5.8 0.014 16.1 5.8 7.3 6 3 2 8 8 8 0 Domain of unknwon function (DUF3824) TEA PF01285.18 EAU84973.1 - 2.5e-21 75.5 0.2 7.6e-21 74.0 0.1 1.8 2 0 0 2 2 2 1 TEA/ATTS domain Cpn10 PF00166.21 EAU84974.1 - 2.9e-28 97.8 0.0 3.3e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MFS_1 PF07690.16 EAU84975.2 - 8.2e-48 163.1 68.6 2.2e-40 138.7 53.5 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 EAU84976.1 - 5e-07 29.5 4.4 7.6e-07 28.9 0.9 3.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU84976.1 - 0.0018 18.1 4.1 0.0025 17.6 0.9 3.1 2 1 0 2 2 2 1 F-box domain DUF745 PF05335.13 EAU84976.1 - 0.0049 16.6 0.4 0.0079 15.9 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) Lebercilin PF15619.6 EAU84976.1 - 0.006 16.3 0.4 0.01 15.5 0.4 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease T3SS_needle_E PF08988.10 EAU84976.1 - 0.013 15.6 1.6 0.028 14.6 1.6 1.5 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle HrpB7 PF09486.10 EAU84976.1 - 0.014 15.8 1.0 0.024 15.0 1.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) PLU-1 PF08429.11 EAU84976.1 - 0.074 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 PLU-1-like protein HR1 PF02185.16 EAU84976.1 - 0.094 12.8 0.7 0.18 11.9 0.7 1.4 1 0 0 1 1 1 0 Hr1 repeat GAS PF13851.6 EAU84976.1 - 0.11 11.8 0.7 0.17 11.2 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 EAU84976.1 - 0.12 10.6 0.4 0.17 10.0 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HOOK PF05622.12 EAU84976.1 - 0.12 10.5 0.2 0.17 10.0 0.2 1.1 1 0 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 EAU84976.1 - 0.2 11.7 4.5 0.37 10.8 4.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein F-box-like PF12937.7 EAU84977.2 - 3.7e-11 42.7 0.5 7.3e-11 41.8 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84977.2 - 9.2e-05 22.2 6.2 0.002 18.0 6.2 2.6 1 1 0 1 1 1 1 F-box domain Arm-DNA-bind_3 PF13356.6 EAU84977.2 - 0.11 12.9 0.6 0.24 11.8 0.6 1.6 2 0 0 2 2 2 0 Arm DNA-binding domain AA_permease_2 PF13520.6 EAU84978.2 - 5.3e-37 127.6 7.6 4.5e-36 124.6 7.6 2.4 1 1 0 1 1 1 1 Amino acid permease dsrm PF00035.26 EAU84979.2 - 0.00013 22.5 0.1 0.00022 21.9 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif HTH_29 PF13551.6 EAU84979.2 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DUF3808 PF10300.9 EAU84983.2 - 6.6e-78 262.6 0.0 3.7e-77 260.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 EAU84983.2 - 0.00018 21.9 1.0 0.19 12.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU84983.2 - 0.00033 20.5 4.7 0.86 9.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU84983.2 - 0.01 16.5 0.1 0.31 11.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU84983.2 - 0.023 14.9 0.2 9.8 6.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU84983.2 - 0.027 14.7 3.2 18 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU84983.2 - 0.16 11.9 0.9 42 4.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4250 PF14056.6 EAU84988.2 - 0.13 12.3 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) PEPcase PF00311.17 EAU84989.2 - 3.8 5.5 5.9 20 3.1 0.0 2.0 1 1 0 2 2 2 0 Phosphoenolpyruvate carboxylase F-box-like PF12937.7 EAU84996.2 - 4.8e-06 26.4 0.0 9.3e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU84996.2 - 0.031 14.1 1.4 0.56 10.2 0.4 3.0 1 1 1 2 2 2 0 F-box domain Helitron_like_N PF14214.6 EAU84997.2 - 5.9e-28 98.4 0.0 1.2e-27 97.4 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAU84997.2 - 8.2e-27 94.3 0.0 1.6e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU84997.2 - 7.4e-12 45.4 0.0 1.6e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU84997.2 - 9.3e-10 39.0 0.0 2.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 EAU84997.2 - 0.13 11.2 0.1 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KCNQC3-Ank-G_bd PF11956.8 EAU85000.2 - 0.053 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 WD40 PF00400.32 EAU85001.1 - 2.3e-14 53.6 2.7 1.7e-07 31.8 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU85001.1 - 0.00011 22.4 0.2 0.019 15.3 0.0 3.3 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Atrophin-1 PF03154.15 EAU85004.2 - 0.99 7.6 16.2 1.6 6.9 16.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family RNA_pol_Rpc4 PF05132.14 EAU85004.2 - 3.5 8.1 9.5 0.54 10.7 5.2 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 ANAPC4_WD40 PF12894.7 EAU85006.1 - 8.1e-05 22.9 0.1 0.2 12.0 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU85006.1 - 0.00056 20.7 0.3 0.099 13.6 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAU85006.1 - 0.027 13.5 0.0 0.057 12.4 0.0 1.5 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein F-box-like PF12937.7 EAU85007.2 - 1e-08 34.9 0.1 4.3e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85007.2 - 0.59 10.1 3.4 11 6.0 3.4 2.7 1 1 0 1 1 1 0 F-box domain Peptidase_C48 PF02902.19 EAU85008.2 - 3.9e-34 118.4 0.2 5.5e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PROCN PF08083.11 EAU85009.2 - 2e-20 72.9 0.1 2.4e-20 72.6 0.1 1.1 1 0 0 1 1 1 1 PROCN (NUC071) domain POR PF01558.18 EAU85010.2 - 0.099 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase CE2_N PF17996.1 EAU85015.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Rick_17kDa_Anti PF05433.15 EAU85015.1 - 0.21 11.4 5.6 0.41 10.6 5.6 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gram_pos_anchor PF00746.21 EAU85015.1 - 0.98 9.4 4.7 1.9 8.5 4.7 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif FAP PF07174.11 EAU85015.1 - 2.4 7.5 22.4 4.3 6.7 22.4 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CbtA PF09490.10 EAU85016.2 - 0.038 13.8 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) LapA_dom PF06305.11 EAU85016.2 - 0.046 13.5 0.5 0.082 12.7 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CE2_N PF17996.1 EAU85016.2 - 0.052 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal stn_TNFRSF12A PF12191.8 EAU85016.2 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Pho88 PF10032.9 EAU85017.1 - 6.3e-74 247.2 0.1 7.1e-74 247.0 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) PH PF00169.29 EAU85018.2 - 0.0047 17.4 0.0 0.048 14.2 0.0 2.3 1 1 0 1 1 1 1 PH domain Cuticle_3 PF11018.8 EAU85018.2 - 1.3 9.2 14.8 0.033 14.4 3.9 3.1 4 0 0 4 4 4 0 Pupal cuticle protein C1 QWRF PF04484.12 EAU85018.2 - 1.4 8.6 5.5 0.38 10.4 1.2 2.2 2 0 0 2 2 2 0 QWRF family Amnionless PF14828.6 EAU85019.2 - 0.26 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless GST_N_2 PF13409.6 EAU85020.2 - 2.3e-21 75.8 0.0 4.1e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU85020.2 - 2.3e-14 53.2 0.0 4.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU85020.2 - 5.8e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU85020.2 - 2.9e-05 24.2 0.0 5.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EAU85020.2 - 0.0015 18.9 0.0 0.025 15.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aldedh PF00171.22 EAU85023.1 - 3.3e-71 240.2 0.0 4.2e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.18 EAU85023.1 - 0.016 16.1 0.0 0.11 13.4 0.0 2.4 2 0 0 2 2 2 0 Fic/DOC family ATP-synt_G PF04718.15 EAU85024.1 - 3.5e-17 63.1 1.1 9.6e-17 61.7 0.1 1.9 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit PriA_C PF18074.1 EAU85024.1 - 0.053 14.3 0.0 0.091 13.6 0.0 1.5 1 1 0 1 1 1 0 Primosomal protein N C-terminal domain HMG_box PF00505.19 EAU85025.2 - 1.1e-12 48.1 0.3 3e-12 46.8 0.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU85025.2 - 1.4e-05 25.6 0.2 3e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 EAU85025.2 - 0.071 13.1 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Complex1_LYR PF05347.15 EAU85028.1 - 2.9e-05 24.0 0.1 2.9e-05 24.0 0.1 3.1 3 0 0 3 3 3 1 Complex 1 protein (LYR family) TCL1_MTCP1 PF01840.17 EAU85028.1 - 0.1 12.2 0.1 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 TCL1/MTCP1 family Phage_holin_3_6 PF07332.11 EAU85029.1 - 0.33 11.0 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NapE PF06796.11 EAU85029.1 - 0.42 10.2 2.1 1.3 8.6 2.1 1.9 1 1 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Ribonuc_L-PSP PF01042.21 EAU85030.2 - 6e-13 48.9 0.0 9.8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP F-box-like PF12937.7 EAU85030.2 - 1.6e-05 24.7 3.3 4.2e-05 23.4 3.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU85030.2 - 0.62 10.6 2.5 17 6.0 0.1 3.5 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF1796 PF08795.10 EAU85033.1 - 0.015 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) LRR_4 PF12799.7 EAU85033.1 - 0.13 12.8 0.8 13 6.3 0.5 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) TauD PF02668.16 EAU85034.2 - 1.9e-56 191.9 0.4 2.4e-56 191.5 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MULE PF10551.9 EAU85035.2 - 1.6e-15 57.3 0.1 4.6e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 EAU85035.2 - 6.1e-09 36.5 0.4 1.3e-08 35.4 0.4 1.5 1 0 0 1 1 1 1 FAR1 DNA-binding domain DUF5575 PF17738.1 EAU85035.2 - 0.012 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5575) Transposase_mut PF00872.18 EAU85035.2 - 0.031 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family APOC4 PF15119.6 EAU85035.2 - 0.06 13.6 0.1 0.2 11.9 0.1 1.9 1 0 0 1 1 1 0 Apolipoprotein C4 Gag_p12 PF01141.18 EAU85035.2 - 0.14 12.5 5.7 0.18 12.2 1.3 2.7 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Helitron_like_N PF14214.6 EAU85037.2 - 2.5e-25 89.8 0.0 4.3e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EAU85037.2 - 1.9e-13 50.3 0.0 3e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU85037.2 - 9.1e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU85037.2 - 9.8e-07 29.2 0.0 6.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 EAU85037.2 - 0.004 16.1 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain MeaB PF03308.16 EAU85037.2 - 0.18 10.8 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EAU85037.2 - 0.18 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zds_C PF08632.10 EAU85038.2 - 0.16 11.7 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Elongin_A PF06881.11 EAU85039.2 - 0.033 14.7 0.0 0.05 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Goodbye PF17109.5 EAU85041.1 - 1.5 9.3 3.9 1.8 9.0 0.5 2.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain COG5 PF10392.9 EAU85041.1 - 3.1 8.0 7.2 1.9 8.6 3.2 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF812 PF05667.11 EAU85041.1 - 6.5 5.5 17.1 0.046 12.6 8.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ZapB PF06005.12 EAU85041.1 - 7.1 7.1 13.3 3.6 8.1 8.6 2.8 3 0 0 3 3 3 0 Cell division protein ZapB TTSSLRR PF12468.8 EAU85042.2 - 0.056 13.7 0.4 0.21 11.9 0.4 1.9 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein KDZ PF18758.1 EAU85043.2 - 1.8e-48 165.1 0.1 4e-48 164.0 0.1 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU85043.2 - 1.1e-25 89.9 0.1 2.6e-25 88.7 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU85043.2 - 0.00013 22.1 0.2 0.00054 20.1 0.0 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases Perilipin PF03036.16 EAU85045.1 - 0.042 12.9 0.1 0.049 12.7 0.1 1.1 1 0 0 1 1 1 0 Perilipin family Myc_target_1 PF15179.6 EAU85045.1 - 0.069 13.0 0.2 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 Myc target protein 1 NCOA_u2 PF16665.5 EAU85046.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Unstructured region on nuclear receptor coactivator protein DUF3327 PF11806.8 EAU85048.2 - 0.021 15.5 0.7 0.054 14.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3327) Aminotran_1_2 PF00155.21 EAU85048.2 - 0.13 11.4 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II DUF4226 PF10774.9 EAU85055.1 - 0.087 13.1 1.3 0.25 11.6 1.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4226) PRANC PF09372.10 EAU85056.1 - 0.00049 20.4 0.2 0.0025 18.1 0.0 2.1 2 0 0 2 2 2 1 PRANC domain F-box PF00646.33 EAU85056.1 - 0.0015 18.3 0.1 0.0032 17.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain 2-Hacid_dh_C PF02826.19 EAU85057.2 - 0.03 13.7 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Miff PF05644.11 EAU85058.2 - 0.12 11.9 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Ribosomal_L37ae PF01780.19 EAU85060.2 - 0.026 14.6 0.1 0.046 13.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family F-box-like PF12937.7 EAU85062.2 - 6.5e-08 32.3 0.1 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85062.2 - 0.0083 16.0 0.1 0.029 14.3 0.1 2.0 1 1 0 1 1 1 1 F-box domain SpoIIIAH PF12685.7 EAU85064.1 - 0.42 10.4 8.4 0.62 9.9 8.4 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 EAU85064.1 - 9.2 4.9 6.9 12 4.6 6.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SH3_1 PF00018.28 EAU85065.2 - 5.4e-12 45.1 0.4 8.5e-12 44.5 0.4 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU85065.2 - 2.6e-11 43.2 0.1 4e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU85065.2 - 1.9e-09 37.1 0.0 3.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Senescence PF06911.12 EAU85065.2 - 0.052 13.9 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein Polysacc_deac_1 PF01522.21 EAU85066.2 - 1.8e-22 79.5 0.0 4.9e-22 78.1 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase ATP-synt_I PF03899.15 EAU85067.1 - 0.007 16.7 0.1 0.21 12.0 0.1 2.0 2 0 0 2 2 2 2 ATP synthase I chain F-box-like PF12937.7 EAU85068.2 - 0.00094 19.0 0.1 0.0018 18.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like Cellulase PF00150.18 EAU85069.2 - 2.9e-05 23.6 0.0 6.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_6 PF01341.17 EAU85070.1 - 9e-98 327.8 0.9 1.1e-97 327.4 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF1996 PF09362.10 EAU85071.2 - 1.1e-78 264.5 1.6 1.3e-78 264.2 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Esterase_phd PF10503.9 EAU85072.2 - 5.1e-19 68.6 0.1 8.6e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EAU85072.2 - 6.7e-13 48.3 5.7 6.7e-13 48.3 5.7 2.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EAU85072.2 - 3.2e-07 30.1 0.0 5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EAU85072.2 - 0.057 13.3 0.1 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1996 PF09362.10 EAU85073.1 - 1.8e-82 276.9 0.5 2.7e-82 276.3 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU85073.1 - 1.7e-11 43.9 12.5 1.7e-11 43.9 12.5 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF1996 PF09362.10 EAU85074.1 - 6.5e-80 268.5 0.1 6.5e-80 268.5 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU85074.1 - 1.4e-11 44.2 12.7 1.4e-11 44.2 12.7 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Pkinase PF00069.25 EAU85079.2 - 5e-63 212.9 0.0 6.8e-38 130.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85079.2 - 2e-38 132.2 0.0 1.4e-23 83.5 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EAU85079.2 - 6.3e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAU85079.2 - 0.011 15.7 0.2 0.011 15.7 0.2 3.8 2 2 1 4 4 4 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAU85079.2 - 0.022 13.7 0.0 0.07 12.1 0.0 1.8 1 0 0 1 1 1 0 Haspin like kinase domain Macscav_rec PF03523.13 EAU85079.2 - 0.12 12.3 0.5 0.35 10.8 0.5 1.8 1 0 0 1 1 1 0 Macrophage scavenger receptor DivIC PF04977.15 EAU85079.2 - 10 6.0 15.7 7.9 6.3 1.1 3.1 2 1 0 2 2 2 0 Septum formation initiator Ferritin_2 PF13668.6 EAU85080.1 - 3.1e-34 118.1 0.5 4.7e-34 117.5 0.5 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyco_hydro_11 PF00457.17 EAU85081.1 - 2.5e-59 199.9 4.4 3e-59 199.6 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF3740 PF12548.8 EAU85081.1 - 0.1 13.0 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Sulfatase protein EptA_B_N PF08019.12 EAU85084.2 - 0.017 15.0 0.1 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB Ricin_B_lectin PF00652.22 EAU85085.2 - 2.1e-13 50.6 8.7 2.2e-13 50.6 6.0 2.1 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU85085.2 - 3e-11 43.9 13.3 8.7e-07 29.6 6.8 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like F-box-like PF12937.7 EAU85086.1 - 2.2e-07 30.7 0.5 6e-07 29.3 0.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU85086.1 - 0.015 15.7 0.2 1.5 9.4 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF16 PF01519.16 EAU85086.1 - 0.081 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF5340 PF17275.2 EAU85086.1 - 0.15 12.2 3.5 0.32 11.2 1.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5340) FlxA PF14282.6 EAU85086.1 - 0.99 9.4 6.6 1.8 8.6 6.6 1.3 1 0 0 1 1 1 0 FlxA-like protein F-box PF00646.33 EAU85086.1 - 2.8 7.9 5.0 31 4.6 0.1 3.1 3 0 0 3 3 3 0 F-box domain SlyX PF04102.12 EAU85086.1 - 3.7 8.3 7.6 1.2 9.9 3.8 2.1 2 0 0 2 2 2 0 SlyX zf-C3HC4_3 PF13920.6 EAU85088.2 - 4.5e-06 26.4 3.8 6.7e-06 25.9 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU85088.2 - 2.8e-05 23.9 6.0 4.5e-05 23.2 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU85088.2 - 0.00014 21.8 5.2 0.00022 21.1 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU85088.2 - 0.00028 20.9 7.1 0.0005 20.0 7.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAU85088.2 - 0.00064 20.0 4.0 0.0011 19.3 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU85088.2 - 0.0018 18.1 4.7 0.003 17.4 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU85088.2 - 0.013 15.3 8.0 0.046 13.6 8.1 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EAU85088.2 - 0.95 9.7 7.3 2.2 8.5 7.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING F-box-like PF12937.7 EAU85089.2 - 1.1e-08 34.8 0.1 2.2e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85089.2 - 0.092 12.7 0.9 0.58 10.1 0.1 2.3 2 0 0 2 2 2 0 F-box domain Pheromone PF08015.11 EAU85090.1 - 0.00044 21.2 7.0 0.0017 19.3 7.0 2.5 1 1 0 1 1 1 1 Fungal mating-type pheromone Hus1 PF04005.12 EAU85091.2 - 4.3e-57 193.5 0.0 4.9e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein UPF0086 PF01868.16 EAU85092.2 - 3.6e-31 106.9 0.0 1.2e-30 105.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Ricin_B_lectin PF00652.22 EAU85093.1 - 4.8e-23 81.8 9.0 4.8e-23 81.8 9.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU85093.1 - 8.6e-14 52.0 24.6 3.8e-08 34.0 0.9 3.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like PIF3 PF05006.12 EAU85093.1 - 0.059 13.4 0.9 1 9.5 0.1 2.3 1 1 1 2 2 2 0 Per os infectivity factor 3 Ricin_B_lectin PF00652.22 EAU85094.1 - 1.9e-20 73.4 4.5 1.9e-20 73.4 4.5 2.2 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU85094.1 - 1e-15 58.2 3.8 0.00023 21.8 2.6 3.4 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like DUF4360 PF14273.6 EAU85095.1 - 2.9e-42 144.6 0.4 3.3e-42 144.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Maf PF02545.14 EAU85097.1 - 2.3e-46 157.7 0.0 2.8e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein PhoLip_ATPase_C PF16212.5 EAU85098.2 - 0.0068 16.2 4.4 0.0068 16.2 4.4 1.8 1 1 1 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal DUF4396 PF14342.6 EAU85098.2 - 0.012 16.0 2.8 0.012 16.0 2.8 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4396) Cytochrom_B561 PF03188.16 EAU85098.2 - 0.13 12.4 2.5 0.38 10.9 2.0 1.9 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Cation_ATPase_C PF00689.21 EAU85098.2 - 0.83 9.3 10.5 0.041 13.6 4.7 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus NUDIX PF00293.28 EAU85100.2 - 1.2e-12 48.0 0.0 1.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain F-box-like PF12937.7 EAU85101.1 - 5.1e-09 35.9 0.0 3.6e-08 33.2 0.0 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85101.1 - 0.006 16.4 2.1 5.1 7.1 0.1 3.6 3 0 0 3 3 3 2 F-box domain Trimer_CC PF08954.11 EAU85101.1 - 0.1 12.1 0.9 0.26 10.9 0.9 1.6 1 0 0 1 1 1 0 Trimerisation motif DUF4407 PF14362.6 EAU85101.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 EAU85102.1 - 2.2e-06 27.5 0.7 5.9e-06 26.1 0.7 1.8 1 0 0 1 1 1 1 F-box-like SPX PF03105.19 EAU85102.1 - 1.2 9.0 10.7 2.3 8.0 10.7 1.5 1 0 0 1 1 1 0 SPX domain F-box-like PF12937.7 EAU85104.1 - 4.5e-09 36.1 0.7 1.7e-08 34.2 0.7 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85104.1 - 2.5 8.1 4.9 9.6 6.2 0.4 3.0 2 1 0 2 2 2 0 F-box domain Aminotran_3 PF00202.21 EAU85105.2 - 5e-105 351.5 0.0 8.2e-103 344.2 0.0 3.0 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EAU85105.2 - 0.0075 15.5 0.0 0.014 14.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II F-box-like PF12937.7 EAU85106.2 - 9.5e-09 35.0 2.4 9.5e-09 35.0 2.4 2.2 2 0 0 2 2 2 1 F-box-like SlyX PF04102.12 EAU85106.2 - 0.068 13.8 0.5 0.2 12.3 0.1 2.0 2 0 0 2 2 2 0 SlyX F-box-like PF12937.7 EAU85107.1 - 6.9e-07 29.1 0.7 6.9e-07 29.1 0.7 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85107.1 - 0.0069 16.2 2.4 0.89 9.5 1.0 3.5 3 1 0 3 3 3 1 F-box domain FliJ PF02050.16 EAU85107.1 - 0.024 14.9 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein FTH PF01827.27 EAU85107.1 - 0.099 12.4 0.2 0.29 10.9 0.2 1.8 1 1 0 1 1 1 0 FTH domain LigT_PEase PF02834.16 EAU85107.1 - 0.21 11.8 1.7 0.71 10.1 0.1 2.5 2 0 0 2 2 2 0 LigT like Phosphoesterase CFEM PF05730.11 EAU85108.2 - 0.14 12.3 0.9 0.28 11.3 0.9 1.4 1 0 0 1 1 1 0 CFEM domain FAD_binding_3 PF01494.19 EAU85110.2 - 4.4e-16 59.1 0.0 6.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAU85110.2 - 2.3e-10 40.2 1.0 4.6e-06 26.1 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU85110.2 - 3.3e-10 40.1 2.8 8.5e-07 28.9 1.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU85110.2 - 1.2e-09 38.3 2.1 3.2e-08 33.7 0.5 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EAU85110.2 - 7.8e-07 29.6 0.4 5.2e-06 26.9 0.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU85110.2 - 2.8e-06 26.7 0.2 4.5e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAU85110.2 - 5.5e-05 22.0 0.2 0.00042 19.1 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EAU85110.2 - 5.9e-05 22.5 0.9 0.025 13.9 0.0 2.8 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EAU85110.2 - 0.00036 19.9 0.1 0.0011 18.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EAU85110.2 - 0.00045 19.6 0.0 0.00087 18.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EAU85110.2 - 0.00058 19.0 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EAU85110.2 - 0.00099 18.6 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EAU85110.2 - 0.0027 16.6 1.2 0.053 12.4 0.2 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EAU85110.2 - 0.028 13.5 0.6 0.11 11.5 0.1 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 EAU85110.2 - 0.04 13.2 0.1 0.083 12.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EAU85110.2 - 0.071 13.4 0.5 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Peroxidase_2 PF01328.17 EAU85113.1 - 4.9e-44 151.1 0.0 7.3e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 RNase_P_Rpp14 PF01900.19 EAU85114.2 - 2.3e-14 53.5 0.0 1.4e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Rpp14/Pop5 family DUF4472 PF14739.6 EAU85115.1 - 0.006 17.3 0.7 0.011 16.5 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) MRPL52 PF18699.1 EAU85115.1 - 0.0073 16.5 0.6 0.015 15.5 0.6 1.5 1 0 0 1 1 1 1 Mitoribosomal protein mL52 BBP1_C PF15272.6 EAU85115.1 - 0.017 15.0 0.2 0.017 15.0 0.2 1.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal ATG16 PF08614.11 EAU85115.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EAU85115.1 - 0.27 11.9 1.8 0.49 11.0 1.8 1.4 1 0 0 1 1 1 0 SlyX WD40_alt PF14077.6 EAU85115.1 - 0.96 9.4 4.8 0.39 10.6 1.4 2.1 1 1 1 2 2 2 0 Alternative WD40 repeat motif Aminotran_1_2 PF00155.21 EAU85117.2 - 9.9e-39 133.5 0.0 5.5e-38 131.1 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EAU85117.2 - 0.001 17.7 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme F-box-like PF12937.7 EAU85118.2 - 1.4e-08 34.5 1.9 2.5e-08 33.7 0.3 2.2 2 0 0 2 2 2 1 F-box-like HIP1_clath_bdg PF16515.5 EAU85118.2 - 0.034 14.7 0.0 0.059 14.0 0.0 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LRR_4 PF12799.7 EAU85118.2 - 0.24 11.9 2.9 7.1 7.2 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Phage_antitermQ PF06530.12 EAU85120.2 - 0.22 11.5 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Phage antitermination protein Q AA_permease_2 PF13520.6 EAU85121.2 - 3.6e-84 283.0 40.2 4.4e-84 282.8 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAU85121.2 - 2e-14 53.1 28.4 2e-14 53.1 28.4 1.6 1 1 1 2 2 2 1 Amino acid permease F-box-like PF12937.7 EAU85123.2 - 7.2e-10 38.6 0.2 9.8e-09 35.0 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85123.2 - 0.071 13.0 2.9 0.14 12.1 0.5 2.8 3 1 0 3 3 3 0 F-box domain RasGAP_C PF03836.15 EAU85123.2 - 0.22 11.7 0.1 0.35 11.0 0.1 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Na_sulph_symp PF00939.19 EAU85125.2 - 9.2e-33 114.0 26.6 1.4e-32 113.4 26.6 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 EAU85125.2 - 3.6e-27 96.3 9.0 2.3e-22 80.5 1.7 2.2 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 EAU85125.2 - 1.3e-22 80.4 34.6 1.3e-18 67.2 22.4 2.2 1 1 1 2 2 2 2 Citrate transporter Orn_Arg_deC_N PF02784.16 EAU85127.1 - 1.6e-77 260.2 0.0 3.9e-77 259.0 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EAU85127.1 - 1.6e-15 57.1 0.0 2.1e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EAU85127.1 - 0.077 12.4 0.0 0.28 10.6 0.0 1.9 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel PTPA PF03095.15 EAU85128.2 - 2.6e-101 339.0 0.0 3.1e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NfrA_C PF13283.6 EAU85128.2 - 0.094 12.2 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term Ku PF02735.16 EAU85129.2 - 1.8e-21 76.8 0.0 7.2e-17 61.8 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 EAU85129.2 - 2.4e-15 57.0 2.8 7.1e-15 55.5 0.1 2.8 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm Ku_N PF03731.15 EAU85129.2 - 5.5e-09 36.1 0.0 5.1e-06 26.4 0.0 2.3 1 1 0 2 2 2 2 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.27 EAU85129.2 - 1.6e-08 34.1 0.3 3.9e-08 32.9 0.3 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.6 EAU85129.2 - 0.0021 18.7 0.0 0.0051 17.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ish1 PF10281.9 EAU85129.2 - 0.024 14.9 0.3 0.088 13.1 0.0 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Glutaredoxin PF00462.24 EAU85130.1 - 1e-18 67.2 0.0 7.5e-18 64.5 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EAU85130.1 - 3.3e-13 49.5 0.0 1e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.11 EAU85130.1 - 8.8e-06 25.7 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EAU85130.1 - 0.0013 19.0 0.1 0.54 10.6 0.0 2.9 2 2 1 3 3 3 2 Thioredoxin-like Phosducin PF02114.16 EAU85130.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin GST_N_3 PF13417.6 EAU85130.1 - 0.019 15.4 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 EAU85130.1 - 0.023 15.1 0.0 1.2 9.6 0.0 2.9 2 1 0 2 2 2 0 Thioredoxin-like domain SH3BGR PF04908.15 EAU85130.1 - 0.05 13.8 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.6 EAU85130.1 - 0.14 12.2 0.1 2.5 8.2 0.0 2.5 3 0 0 3 3 3 0 Thioredoxin domain zf-MYND PF01753.18 EAU85132.1 - 2.6e-09 37.0 8.4 4.6e-09 36.2 8.4 1.4 1 0 0 1 1 1 1 MYND finger Ank_5 PF13857.6 EAU85132.1 - 0.011 16.1 0.0 14 6.1 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF3552 PF12072.8 EAU85134.1 - 0.0014 18.1 46.9 1.4 8.3 19.6 3.5 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) SAM_PNT PF02198.16 EAU85134.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fib_alpha PF08702.10 EAU85134.1 - 0.55 10.4 8.2 0.15 12.2 1.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tet_JBP PF12851.7 EAU85137.2 - 1e-08 35.0 0.0 2e-08 34.0 0.0 1.3 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HMG_box_2 PF09011.10 EAU85139.1 - 0.014 16.0 1.0 0.074 13.6 1.0 2.3 1 1 0 1 1 1 0 HMG-box domain Baculo_PEP_C PF04513.12 EAU85140.2 - 0.0079 16.2 0.8 1.9 8.5 0.0 3.2 2 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.11 EAU85140.2 - 0.0079 15.1 2.2 0.014 14.3 2.2 1.4 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like TSKS PF15358.6 EAU85140.2 - 0.0092 14.4 0.9 0.022 13.2 0.0 2.1 2 0 0 2 2 2 1 Testis-specific serine kinase substrate DLP_helical PF18709.1 EAU85140.2 - 0.071 12.3 3.3 4.3 6.4 0.1 2.6 1 1 0 2 2 2 0 Dynamin-like helical domain DUF445 PF04286.12 EAU85140.2 - 0.082 12.7 4.1 0.13 12.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1664 PF07889.12 EAU85140.2 - 0.099 12.7 4.3 0.68 10.0 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) EzrA PF06160.12 EAU85140.2 - 0.1 10.8 0.0 0.2 9.8 0.0 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA BAR PF03114.18 EAU85140.2 - 0.11 12.2 0.6 1.2 8.8 0.1 2.2 1 1 1 2 2 2 0 BAR domain Fib_alpha PF08702.10 EAU85140.2 - 0.15 12.3 3.8 5.6 7.1 0.0 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HD_2 PF12917.7 EAU85140.2 - 0.16 11.7 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme TRPM_tetra PF16519.5 EAU85140.2 - 0.41 10.8 2.2 10 6.3 0.0 2.7 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Laminin_II PF06009.12 EAU85140.2 - 0.52 10.3 3.7 1.9 8.5 0.1 2.7 2 1 1 3 3 3 0 Laminin Domain II F-box-like PF12937.7 EAU85141.1 - 0.0012 18.7 0.5 0.003 17.4 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85141.1 - 0.14 12.1 1.5 0.87 9.5 1.5 2.4 1 1 0 1 1 1 0 F-box domain Prenyltransf PF01255.19 EAU85142.1 - 5.9e-79 264.7 0.0 7.1e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4426 PF14467.6 EAU85142.1 - 0.022 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) HTH_17 PF12728.7 EAU85142.1 - 0.071 13.3 0.0 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Trypsin_2 PF13365.6 EAU85144.1 - 0.00033 21.6 0.1 0.08 13.8 0.0 2.4 2 1 0 2 2 2 2 Trypsin-like peptidase domain Peptidase_S64 PF08192.11 EAU85144.1 - 0.014 14.0 0.6 0.02 13.4 0.4 1.4 1 1 0 1 1 1 0 Peptidase family S64 DUF31 PF01732.16 EAU85144.1 - 1.2 8.6 6.0 2 7.9 1.4 2.6 1 1 0 2 2 2 0 Putative peptidase (DUF31) DUF3841 PF12952.7 EAU85149.2 - 0.059 13.2 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) MFS_1 PF07690.16 EAU85151.2 - 1.8e-33 115.9 22.8 1.8e-33 115.9 22.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU85151.2 - 2.4e-05 23.4 23.0 0.00051 19.0 23.0 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EAU85151.2 - 0.0029 16.1 0.5 0.0029 16.1 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_3 PF13738.6 EAU85152.2 - 2.2e-16 60.0 0.2 1.6e-09 37.5 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EAU85152.2 - 6.8e-14 51.2 0.1 3.6e-08 32.3 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EAU85152.2 - 2.3e-12 46.8 0.1 4.5e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAU85152.2 - 2.8e-08 33.3 0.1 3.2e-05 23.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EAU85152.2 - 0.00021 21.5 0.6 0.00055 20.1 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAU85152.2 - 0.0031 17.5 0.6 0.67 9.9 0.3 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EAU85152.2 - 0.0068 15.7 0.1 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EAU85152.2 - 0.0083 15.7 1.5 0.078 12.6 0.1 2.7 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAU85152.2 - 0.015 14.4 0.3 0.027 13.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EAU85152.2 - 0.028 15.0 0.0 0.22 12.1 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAU85152.2 - 0.038 13.1 0.7 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 EAU85152.2 - 0.11 12.1 0.1 8.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA IF2_N PF04760.15 EAU85152.2 - 0.13 12.1 0.4 24 4.8 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region 2-Hacid_dh_C PF02826.19 EAU85152.2 - 0.16 11.3 0.0 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EAU85152.2 - 0.19 12.0 0.0 0.46 10.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain CoaE PF01121.20 EAU85154.1 - 1.6e-61 207.1 0.0 2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EAU85154.1 - 1.5e-05 25.6 0.0 4.1e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EAU85154.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAU85154.1 - 0.041 14.0 0.0 0.7 10.0 0.0 2.8 1 1 1 2 2 2 0 AAA domain PRK PF00485.18 EAU85154.1 - 0.15 11.8 0.9 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family zf-C2H2_4 PF13894.6 EAU85157.1 - 0.42 11.6 1.8 3.7 8.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU85157.1 - 1.1 9.8 3.0 1.8 9.1 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type HgmA PF04209.13 EAU85158.2 - 1.5e-156 521.4 0.0 3.4e-156 520.2 0.0 1.5 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Transketolase_N PF00456.21 EAU85159.2 - 4.1e-16 58.9 0.7 6.8e-15 54.8 0.7 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EAU85159.2 - 2e-08 34.1 0.0 1.8e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EAU85159.2 - 7.8e-05 22.4 0.3 0.00016 21.4 0.3 1.5 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 EAU85159.2 - 0.00013 21.8 0.1 0.00062 19.6 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EAU85159.2 - 0.013 14.5 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Cyanate_lyase PF02560.14 EAU85164.2 - 3e-33 113.5 0.0 4.7e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EAU85164.2 - 0.11 12.9 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Complex1_LYR_2 PF13233.6 EAU85165.2 - 5.5e-18 65.5 0.1 9.6e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EAU85165.2 - 5.3e-10 39.2 0.6 1.4e-09 37.9 0.0 2.0 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Sfi1 PF08457.10 EAU85165.2 - 0.086 11.4 0.9 0.29 9.6 0.0 1.8 2 0 0 2 2 2 0 Sfi1 spindle body protein Pkinase_Tyr PF07714.17 EAU85167.2 - 1.6e-37 129.2 0.0 2.7e-37 128.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU85167.2 - 4.3e-35 121.4 0.0 7.1e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EAU85167.2 - 0.0027 17.1 0.0 0.0052 16.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EAU85167.2 - 0.035 14.0 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.25 EAU85168.2 - 1.4e-53 182.1 0.0 2.1e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAU85168.2 - 2.9e-34 118.0 0.0 5.2e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EAU85168.2 - 0.00061 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EAU85168.2 - 0.00081 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.9 EAU85168.2 - 0.15 12.3 1.0 0.29 11.5 0.0 1.9 2 1 0 2 2 2 0 Misato Segment II tubulin-like domain DUF1479 PF07350.12 EAU85169.2 - 1.9e-112 376.1 0.0 2.4e-112 375.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EAU85169.2 - 0.00048 20.5 0.2 0.029 14.6 0.1 2.8 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 EAU85170.1 - 9e-38 130.1 22.9 1.4e-37 129.5 22.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.6 EAU85170.1 - 0.041 14.2 3.3 0.12 12.7 3.3 1.9 1 0 0 1 1 1 0 Stage V sporulation protein AB DUF1996 PF09362.10 EAU85171.2 - 1.2e-75 254.5 0.6 1.6e-75 254.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pkinase PF00069.25 EAU85172.2 - 2.5e-25 89.4 0.0 3.7e-24 85.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85172.2 - 2.8e-08 33.3 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 EAU85172.2 - 0.0067 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.11 EAU85172.2 - 0.014 14.4 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EAU85172.2 - 0.048 13.6 0.0 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAU85172.2 - 0.23 10.2 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_L30 PF00327.20 EAU85175.2 - 9.2e-13 47.9 0.0 1.4e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DEAD PF00270.29 EAU85177.2 - 1e-12 48.2 0.0 2.5e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU85177.2 - 2.6e-09 37.4 0.3 1.9e-07 31.4 0.3 3.3 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU85177.2 - 1.5e-06 28.3 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit F-box-like PF12937.7 EAU85179.2 - 0.00043 20.1 0.0 0.00099 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85179.2 - 0.0051 16.7 0.0 0.02 14.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EAU85179.2 - 0.43 11.1 10.9 24 5.5 0.1 6.2 6 2 1 7 7 7 0 Leucine Rich repeats (2 copies) Sdh_cyt PF01127.22 EAU85181.2 - 7.5e-25 87.3 0.9 9.6e-25 87.0 0.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF572 PF04502.13 EAU85185.1 - 0.0012 18.6 13.8 0.0016 18.2 13.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) SLC12 PF03522.15 EAU85185.1 - 0.75 8.8 9.2 1 8.3 9.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Rrn6 PF10214.9 EAU85185.1 - 1.3 7.5 10.9 1.6 7.1 10.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Atg14 PF10186.9 EAU85185.1 - 1.8 7.6 13.5 2.4 7.2 13.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CemA PF03040.14 EAU85185.1 - 5 7.0 6.4 8.6 6.2 6.4 1.4 1 0 0 1 1 1 0 CemA family RR_TM4-6 PF06459.12 EAU85185.1 - 7.8 6.2 14.7 11 5.8 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EAU85185.1 - 9.4 4.9 9.7 12 4.5 9.7 1.1 1 0 0 1 1 1 0 Presenilin OmpH PF03938.14 EAU85185.1 - 9.9 6.5 20.0 22 5.4 20.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) F-box PF00646.33 EAU85187.1 - 2e-06 27.5 0.0 8.1e-06 25.6 0.0 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU85187.1 - 5.3e-05 23.0 0.1 0.00016 21.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU85187.1 - 0.35 11.4 13.5 13 6.3 0.1 5.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) FixQ PF05545.11 EAU85188.1 - 0.014 15.4 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ AJAP1_PANP_C PF15298.6 EAU85188.1 - 0.096 12.9 5.5 0.025 14.8 2.2 1.6 2 0 0 2 2 2 0 AJAP1/PANP C-terminus MAP17 PF15807.5 EAU85188.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Podoplanin PF05808.11 EAU85188.1 - 0.26 11.4 4.3 0.071 13.2 0.6 1.9 2 0 0 2 2 2 0 Podoplanin MGC-24 PF05283.11 EAU85188.1 - 0.35 11.3 5.7 0.095 13.2 1.1 2.4 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin F-box-like PF12937.7 EAU85190.1 - 9.9e-07 28.6 0.4 3.3e-06 26.9 0.4 2.0 1 0 0 1 1 1 1 F-box-like Asp_protease_2 PF13650.6 EAU85191.2 - 0.0013 19.3 0.0 0.0046 17.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease EnY2 PF10163.9 EAU85191.2 - 0.17 12.2 0.5 0.51 10.8 0.5 1.7 1 0 0 1 1 1 0 Transcription factor e(y)2 LRR_8 PF13855.6 EAU85193.1 - 0.012 15.3 1.7 0.034 13.9 0.2 2.3 2 1 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 EAU85193.1 - 0.033 14.3 1.8 1.6 9.0 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 EAU85193.1 - 0.091 13.2 3.1 0.79 10.2 0.4 2.8 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) AAA PF00004.29 EAU85195.2 - 3.3e-93 309.1 0.0 2.2e-46 157.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU85195.2 - 5.4e-23 80.5 0.2 1.4e-10 40.8 0.0 3.0 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 EAU85195.2 - 1.9e-15 57.0 0.0 4.2e-08 33.1 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EAU85195.2 - 2.3e-12 47.6 1.2 0.00095 19.6 0.1 4.5 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EAU85195.2 - 3.4e-12 46.8 0.3 0.013 15.8 0.0 5.2 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 EAU85195.2 - 1.6e-10 41.3 0.0 0.00017 21.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EAU85195.2 - 6.1e-10 39.5 0.0 0.00072 19.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAU85195.2 - 6.3e-10 39.2 0.5 0.0035 17.4 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EAU85195.2 - 1e-08 34.8 0.0 9.5e-05 21.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EAU85195.2 - 1.1e-07 31.9 0.0 0.009 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EAU85195.2 - 2.6e-07 31.0 0.0 0.024 15.0 0.0 2.8 2 1 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EAU85195.2 - 4.3e-07 29.5 0.2 0.028 13.8 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAU85195.2 - 1.9e-06 27.8 0.0 0.074 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EAU85195.2 - 2.5e-06 27.9 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EAU85195.2 - 7.9e-06 25.3 0.0 0.052 12.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 EAU85195.2 - 8.1e-06 25.7 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAU85195.2 - 1.1e-05 25.4 0.4 0.1 12.5 0.0 3.4 3 1 0 4 4 3 2 NACHT domain ABC_tran PF00005.27 EAU85195.2 - 2.1e-05 25.1 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter TsaE PF02367.17 EAU85195.2 - 2.6e-05 24.2 0.0 0.09 12.8 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 EAU85195.2 - 3.2e-05 24.2 0.0 0.017 15.3 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activat PF00158.26 EAU85195.2 - 3.8e-05 23.5 0.1 0.39 10.4 0.0 3.7 3 1 0 3 3 3 2 Sigma-54 interaction domain Rad17 PF03215.15 EAU85195.2 - 5.5e-05 23.2 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_17 PF13207.6 EAU85195.2 - 7.8e-05 23.1 0.0 0.14 12.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 EAU85195.2 - 8e-05 22.6 0.0 0.09 12.8 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EAU85195.2 - 0.0001 22.9 0.0 0.39 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EAU85195.2 - 0.00024 20.7 0.0 0.63 9.5 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 EAU85195.2 - 0.00026 20.4 0.2 1.6 8.0 0.0 3.2 2 1 0 3 3 3 1 KaiC Viral_helicase1 PF01443.18 EAU85195.2 - 0.00035 20.4 0.0 0.56 9.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EAU85195.2 - 0.00036 20.2 2.0 2.8 7.5 0.0 4.2 3 1 0 4 4 4 1 AAA domain NB-ARC PF00931.22 EAU85195.2 - 0.00079 18.7 0.0 1.5 7.9 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 EAU85195.2 - 0.00092 19.3 0.0 1.3 9.1 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_11 PF13086.6 EAU85195.2 - 0.0011 18.8 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EAU85195.2 - 0.0024 17.0 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 SKI PF01202.22 EAU85195.2 - 0.0029 17.7 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase PhoH PF02562.16 EAU85195.2 - 0.0029 17.1 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein ATPase_2 PF01637.18 EAU85195.2 - 0.0049 16.8 0.0 3.2 7.6 0.0 2.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EAU85195.2 - 0.0059 15.8 0.0 0.2 10.8 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EAU85195.2 - 0.0094 15.7 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AFG1_ATPase PF03969.16 EAU85195.2 - 0.011 14.6 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase Bac_DnaA PF00308.18 EAU85195.2 - 0.018 14.9 0.0 7.8 6.3 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein DUF2075 PF09848.9 EAU85195.2 - 0.026 13.8 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EAU85195.2 - 0.057 13.3 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 EAU85195.2 - 0.11 12.2 0.0 20 4.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EAU85195.2 - 0.11 12.8 0.9 24 5.3 0.2 2.9 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EAU85196.2 - 6.1e-19 68.2 24.1 1.4e-14 53.8 17.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DPM2 PF07297.12 EAU85196.2 - 0.083 13.2 0.3 0.083 13.2 0.3 3.0 4 0 0 4 4 4 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HA2 PF04408.23 EAU85197.2 - 2.5e-23 82.4 0.0 5.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAU85197.2 - 8.6e-12 45.3 0.0 2.6e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAU85197.2 - 3.1e-11 43.6 0.0 1.9e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAU85197.2 - 5.2e-06 26.8 0.0 3.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EAU85197.2 - 6.1e-06 26.1 0.3 2.1e-05 24.4 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EAU85197.2 - 6.1e-05 23.4 0.2 0.00013 22.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU85197.2 - 0.001 18.8 0.1 0.0024 17.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EAU85197.2 - 0.0014 18.3 0.6 0.01 15.5 0.2 2.5 3 1 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EAU85197.2 - 0.02 15.0 0.1 0.23 11.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU85197.2 - 0.028 13.9 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAU85197.2 - 0.038 14.5 0.0 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 EAU85197.2 - 0.039 13.9 0.8 1.6 8.8 0.8 2.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EAU85197.2 - 0.1 12.4 0.0 16 5.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein GrpE PF01025.19 EAU85197.2 - 0.2 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 GrpE DEAD PF00270.29 EAU85201.2 - 3.2e-17 62.9 0.0 5.1e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU85201.2 - 1.2e-15 57.8 0.0 4.2e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU85201.2 - 2.3e-06 27.7 0.0 3.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 EAU85201.2 - 0.15 12.8 0.5 0.33 11.7 0.5 1.6 1 0 0 1 1 1 0 RecQ zinc-binding Pox_polyA_pol PF03296.13 EAU85202.2 - 0.17 11.8 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Protoglobin PF11563.8 EAU85203.1 - 5.6e-40 136.8 0.7 7.1e-40 136.5 0.7 1.1 1 0 0 1 1 1 1 Protoglobin DUF848 PF05852.11 EAU85203.1 - 0.05 13.7 0.0 5.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) F-box-like PF12937.7 EAU85204.2 - 2.8e-15 55.9 0.4 4.9e-14 52.0 0.3 2.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU85205.1 - 2.9e-07 30.3 2.2 1.5e-05 24.8 0.7 3.2 2 1 0 2 2 2 2 F-box-like F-box-like PF12937.7 EAU85208.1 - 2.2e-06 27.5 0.9 6.9e-06 25.9 0.9 2.0 1 0 0 1 1 1 1 F-box-like LRR_9 PF14580.6 EAU85208.1 - 0.0021 17.6 0.7 1.4 8.4 0.1 3.2 3 0 0 3 3 3 3 Leucine-rich repeat Cupin_1 PF00190.22 EAU85209.1 - 1.2e-41 141.8 0.1 1.5e-19 70.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EAU85209.1 - 1.4e-29 101.6 0.9 8.2e-14 51.1 0.0 2.6 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 EAU85209.1 - 3.7e-10 39.4 0.0 0.00072 19.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EAU85209.1 - 2.9e-07 30.5 0.2 1.4e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 EAU85209.1 - 3.7e-06 26.9 0.0 0.00043 20.2 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 EAU85209.1 - 0.00015 22.0 0.0 0.037 14.2 0.0 2.2 2 0 0 2 2 2 2 ARD/ARD' family 3-HAO PF06052.12 EAU85209.1 - 0.0038 16.9 0.0 0.46 10.1 0.0 2.5 3 0 0 3 3 3 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.12 EAU85209.1 - 0.0047 16.4 0.0 0.23 10.9 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 EAU85209.1 - 0.14 11.9 0.0 1.2 8.8 0.0 2.3 1 1 0 2 2 2 0 Cupin-like domain Tantalus PF15386.6 EAU85211.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 Drosophila Tantalus-like DUF829 PF05705.14 EAU85215.2 - 6.3e-25 88.5 0.0 1.6e-13 51.1 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) Thg1C PF14413.6 EAU85216.2 - 3.3e-44 150.0 1.0 1.8e-43 147.6 1.0 2.0 1 1 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 EAU85216.2 - 4.8e-23 81.5 0.0 7.4e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase SPX PF03105.19 EAU85216.2 - 1.6 8.6 13.9 2.1 8.2 13.9 1.2 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EAU85216.2 - 2.2 7.4 20.4 2.8 7.0 20.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ATF7IP_BD PF16788.5 EAU85216.2 - 3.3 7.8 13.7 4.4 7.4 13.7 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain SRP-alpha_N PF04086.13 EAU85216.2 - 7.8 6.3 11.3 12 5.8 11.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Abhydrolase_6 PF12697.7 EAU85217.2 - 1.6e-24 87.7 0.1 2.8e-24 87.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU85217.2 - 5.9e-08 32.3 0.0 9.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAU85217.2 - 1.3e-07 31.5 0.0 0.00036 20.3 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 EAU85217.2 - 0.0048 17.0 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain MAGE_N PF12440.8 EAU85217.2 - 0.18 12.5 14.0 5.8 7.7 2.6 3.3 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal SIR2 PF02146.17 EAU85218.2 - 5.6e-22 78.5 0.0 9.1e-09 35.5 0.0 3.3 2 2 1 3 3 3 3 Sir2 family AMP-binding PF00501.28 EAU85219.2 - 6.1e-75 252.4 0.7 1.8e-73 247.6 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU85219.2 - 0.012 16.6 0.0 0.032 15.2 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Cation_ATPase_C PF00689.21 EAU85219.2 - 0.026 14.2 10.1 0.068 12.9 9.8 1.9 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF4396 PF14342.6 EAU85219.2 - 0.079 13.3 2.6 0.19 12.0 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Cytochrom_B561 PF03188.16 EAU85219.2 - 0.091 12.9 1.3 0.35 11.0 0.8 1.8 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 PhoLip_ATPase_C PF16212.5 EAU85219.2 - 4.2 7.1 15.1 0.051 13.3 6.4 1.9 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal CK_II_beta PF01214.18 EAU85220.2 - 4.5e-80 267.8 0.0 5.3e-80 267.5 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PTCB-BRCT PF12738.7 EAU85222.2 - 4.4e-16 58.6 0.0 1.5e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.26 EAU85222.2 - 1.8e-08 34.6 0.0 0.00044 20.6 0.0 3.6 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAU85222.2 - 0.0029 18.0 0.0 0.27 11.7 0.0 3.1 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EAU85222.2 - 0.096 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Forkhead PF00250.18 EAU85223.1 - 9e-27 93.2 0.0 1.5e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain DcpS_C PF11969.8 EAU85225.2 - 2.1e-11 44.3 0.2 2.7e-11 43.9 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.7 EAU85228.2 - 0.00022 21.0 0.8 0.00047 20.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85228.2 - 0.00081 19.2 2.3 0.001 18.9 0.7 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EAU85228.2 - 0.006 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 F-box DUF4139 PF13598.6 EAU85229.1 - 5e-32 111.3 0.0 9.4e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EAU85229.1 - 3e-16 59.7 1.4 3e-16 59.7 1.4 2.2 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 EAU85229.1 - 0.0072 17.2 16.0 0.01 16.6 10.9 2.5 2 0 0 2 2 2 1 Nucleoporin FG repeat region MFS_1 PF07690.16 EAU85232.2 - 7e-15 54.8 46.3 8.2e-14 51.3 35.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 EAU85232.2 - 0.005 16.9 1.2 0.005 16.9 1.2 4.0 2 2 1 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III PS_Dcarbxylase PF02666.15 EAU85233.1 - 5.7e-38 130.5 0.0 7.7e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EAU85233.1 - 1.3e-34 119.1 0.0 2.2e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.6 EAU85233.1 - 0.013 15.4 0.1 5.1 7.1 0.0 2.6 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain AMP-binding PF00501.28 EAU85234.1 - 9.1e-83 278.2 0.0 1.2e-82 277.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Cation_ATPase_C PF00689.21 EAU85234.1 - 0.0021 17.8 4.8 0.0021 17.8 4.8 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus PhoLip_ATPase_C PF16212.5 EAU85234.1 - 0.0077 16.0 5.4 0.0077 16.0 5.4 1.6 1 1 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal AMP-binding_C PF13193.6 EAU85234.1 - 0.0083 17.1 0.0 0.024 15.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cytochrom_B561 PF03188.16 EAU85234.1 - 0.15 12.2 2.0 0.32 11.1 2.0 1.6 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Arrestin_N PF00339.29 EAU85235.1 - 0.00087 19.4 0.0 0.0024 17.9 0.0 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EAU85235.1 - 0.0035 17.8 0.0 0.034 14.6 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain COX6B PF02297.17 EAU85237.1 - 2.5e-20 72.5 4.7 3.7e-20 71.9 4.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EAU85237.1 - 0.00098 19.4 0.5 0.0021 18.3 0.4 1.6 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 RINGv PF12906.7 EAU85237.1 - 0.033 14.3 0.1 0.033 14.3 0.1 1.9 2 1 0 2 2 2 0 RING-variant domain RabGAP-TBC PF00566.18 EAU85238.2 - 5.3e-49 166.8 0.0 9.3e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain COPIIcoated_ERV PF07970.12 EAU85239.1 - 7.1e-37 127.4 1.8 9.9e-37 126.9 1.8 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EAU85239.1 - 1.8e-21 76.3 0.0 3e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) BTB PF00651.31 EAU85241.2 - 0.04 14.2 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain GABP-alpha PF11620.8 EAU85242.1 - 0.16 12.2 0.0 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 GA-binding protein alpha chain Glyco_hydro_61 PF03443.14 EAU85243.2 - 8.4e-50 169.6 0.0 1.1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4236 PF14020.6 EAU85243.2 - 0.042 14.4 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) CBM_1 PF00734.18 EAU85243.2 - 4.6 7.3 9.2 6.3 6.9 1.2 2.6 2 0 0 2 2 2 0 Fungal cellulose binding domain Abhydrolase_1 PF00561.20 EAU85244.2 - 2.6e-21 76.4 0.1 4.3e-21 75.7 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU85244.2 - 1.6e-17 64.9 0.1 2.1e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU85244.2 - 1.3e-10 40.9 0.0 2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EAU85244.2 - 5.5e-09 36.5 0.0 8.7e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 EAU85244.2 - 4e-05 23.2 0.0 6.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAU85244.2 - 8.1e-05 22.4 0.1 0.00068 19.4 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 EAU85244.2 - 0.00049 20.0 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 EAU85244.2 - 0.002 18.0 0.0 0.0026 17.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 EAU85244.2 - 0.0026 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF900 PF05990.12 EAU85244.2 - 0.0094 15.5 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 EAU85244.2 - 0.0099 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) LCAT PF02450.15 EAU85244.2 - 0.021 14.0 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase VirJ PF06057.11 EAU85244.2 - 0.068 13.0 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Chlorophyllase PF07224.11 EAU85244.2 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Steroid_dh PF02544.16 EAU85246.1 - 2.9e-31 108.5 3.3 2.9e-31 108.5 3.3 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 EAU85246.1 - 5.9e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Sde2_N_Ubi PF13019.6 EAU85246.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain COesterase PF00135.28 EAU85247.2 - 4e-82 276.7 0.0 1e-80 272.1 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU85247.2 - 7.9e-05 22.6 0.1 0.00028 20.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU85247.2 - 0.013 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAU85248.2 - 9.6e-14 51.6 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU85248.2 - 6.3e-13 49.8 0.0 8.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EAU85248.2 - 2.8e-10 40.7 0.0 5.1e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EAU85248.2 - 5.8e-10 38.8 0.0 7.8e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EAU85248.2 - 4e-07 30.0 0.2 1.7e-05 24.6 0.2 2.3 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EAU85248.2 - 9.5e-07 28.5 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 EAU85248.2 - 3.3e-05 22.9 0.0 5.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EAU85248.2 - 7.9e-05 21.8 0.0 0.00016 20.8 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase DUF900 PF05990.12 EAU85248.2 - 0.0047 16.5 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Palm_thioest PF02089.15 EAU85248.2 - 0.0076 16.1 0.0 0.0098 15.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 EAU85248.2 - 0.0082 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EAU85248.2 - 0.024 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 EAU85248.2 - 0.038 13.6 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 EAU85248.2 - 0.072 12.6 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF915 PF06028.11 EAU85248.2 - 0.11 11.8 0.1 0.95 8.7 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Arv1 PF04161.13 EAU85250.2 - 1.6e-36 126.4 0.0 2.1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family zf-Sec23_Sec24 PF04810.15 EAU85250.2 - 0.022 14.8 0.8 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger TM_helix PF05552.12 EAU85250.2 - 0.062 13.3 1.3 0.19 11.7 1.0 1.9 1 1 0 1 1 1 0 Conserved TM helix DUF410 PF04190.13 EAU85251.2 - 9.4e-72 241.9 0.0 1.1e-71 241.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Staufen_C PF16482.5 EAU85253.1 - 0.00024 21.2 0.0 0.00027 21.1 0.0 1.2 1 0 0 1 1 1 1 Staufen C-terminal domain dsrm PF00035.26 EAU85253.1 - 0.0011 19.7 0.0 0.0016 19.1 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif HSBP1 PF06825.12 EAU85255.1 - 1.4e-21 76.1 4.2 1.8e-21 75.7 4.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 GOLGA2L5 PF15070.6 EAU85255.1 - 0.0081 14.9 0.1 0.0088 14.8 0.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 FdhE PF04216.12 EAU85255.1 - 0.0099 15.8 0.1 0.012 15.5 0.1 1.0 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation Baculo_PEP_C PF04513.12 EAU85255.1 - 0.015 15.4 0.2 0.018 15.1 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 EAU85255.1 - 0.025 14.5 0.2 0.4 10.6 0.2 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin CLZ PF16526.5 EAU85255.1 - 0.055 13.8 0.1 0.075 13.4 0.1 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EspB PF05802.11 EAU85255.1 - 0.06 13.3 0.2 0.065 13.2 0.2 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein Gti1_Pac2 PF09729.9 EAU85258.2 - 1.1e-49 169.0 0.8 2.5e-39 135.2 0.2 2.5 1 1 1 2 2 2 2 Gti1/Pac2 family Tfb2 PF03849.14 EAU85259.2 - 1.3e-110 369.8 0.0 1.7e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EAU85259.2 - 2.1e-25 88.9 0.1 4.2e-25 88.0 0.1 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EAU85259.2 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank_2 PF12796.7 EAU85260.2 - 5.3e-39 132.7 0.4 4.8e-20 71.9 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU85260.2 - 2.7e-37 126.6 0.9 2.1e-17 63.3 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU85260.2 - 3.3e-35 116.1 0.2 5.9e-07 29.3 0.0 6.1 5 1 1 6 6 6 5 Ankyrin repeat Ank PF00023.30 EAU85260.2 - 6.5e-33 111.7 4.6 4.3e-06 26.9 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAU85260.2 - 2.2e-30 104.3 2.8 1.3e-07 31.8 0.0 5.9 2 1 4 6 6 6 6 Ankyrin repeats (many copies) DUF1996 PF09362.10 EAU85261.1 - 5.4e-81 272.0 0.5 7.2e-81 271.6 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Macoilin PF09726.9 EAU85262.2 - 0.69 8.4 1.8 0.95 7.9 1.8 1.1 1 0 0 1 1 1 0 Macoilin family Terpene_synth_C PF03936.16 EAU85264.1 - 6.1e-09 35.6 0.0 7.9e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 EAU85264.1 - 0.00011 21.1 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) SPOB_ab PF14682.6 EAU85264.1 - 0.0069 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal Zmiz1_N PF18028.1 EAU85264.1 - 0.13 12.6 0.1 1.5 9.2 0.0 2.2 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain RRM_1 PF00076.22 EAU85265.1 - 0.00023 20.9 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRI PF15325.6 EAU85265.1 - 0.84 10.8 3.9 1.8 9.7 3.9 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection SPA PF08616.10 EAU85266.2 - 1.2e-08 34.9 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis COesterase PF00135.28 EAU85269.2 - 2.6e-85 287.2 0.0 5.7e-85 286.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU85269.2 - 2.1e-08 34.3 2.0 3.6e-07 30.2 2.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU85269.2 - 0.15 11.5 0.3 0.26 10.7 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.16 EAU85270.2 - 1.2e-35 123.2 63.9 1.4e-30 106.4 34.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU85270.2 - 6.8e-08 31.8 24.3 2.6e-07 29.9 24.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EAU85270.2 - 0.00031 19.3 0.6 0.00031 19.3 0.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EAU85271.2 - 9.8e-34 116.8 62.0 1.1e-30 106.8 30.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EAU85271.2 - 0.0011 17.5 0.7 0.002 16.6 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Amidohydro_1 PF01979.20 EAU85273.2 - 2.4e-67 227.7 0.5 5e-67 226.7 0.5 1.5 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EAU85273.2 - 9.8e-56 187.3 2.4 2.4e-55 186.1 2.4 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EAU85273.2 - 7.2e-43 144.6 0.1 1.6e-42 143.5 0.1 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EAU85273.2 - 2.3e-40 136.9 0.0 6.5e-40 135.4 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EAU85273.2 - 0.00038 20.0 0.8 0.0024 17.4 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase family Peptidase_C97 PF05903.14 EAU85275.2 - 0.0041 16.9 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain RNase_PH PF01138.21 EAU85276.2 - 1.5e-07 32.0 9.3 0.0021 18.6 0.0 2.7 1 1 1 2 2 2 2 3' exoribonuclease family, domain 1 CTP_transf_like PF01467.26 EAU85276.2 - 0.012 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase-like Vps39_1 PF10366.9 EAU85277.2 - 2e-26 92.4 1.4 9.7e-26 90.2 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EAU85277.2 - 7e-21 74.7 0.1 1.4e-20 73.7 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EAU85277.2 - 2.7e-12 46.8 1.8 3e-10 40.2 0.3 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_4 PF07721.14 EAU85277.2 - 0.0011 19.4 4.4 0.74 10.6 1.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU85277.2 - 0.002 17.9 7.1 5.3 7.0 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAU85277.2 - 0.0052 17.3 3.7 0.04 14.4 0.2 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU85277.2 - 0.026 14.8 7.3 6.1 7.2 0.3 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU85277.2 - 0.036 14.2 8.6 11 6.5 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat CNH PF00780.22 EAU85277.2 - 0.053 13.1 0.0 0.18 11.4 0.0 1.8 2 1 0 2 2 2 0 CNH domain TPR_7 PF13176.6 EAU85277.2 - 0.081 13.0 6.7 21 5.4 0.2 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU85277.2 - 0.1 13.4 5.1 56 4.9 0.3 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 EAU85278.2 - 3.8e-25 88.3 0.1 2e-10 41.1 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU85278.2 - 4.9e-24 84.4 7.3 8.5e-07 29.4 0.0 6.7 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU85278.2 - 3.3e-21 75.1 3.5 6e-06 26.4 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU85278.2 - 1.1e-17 62.2 2.2 0.0012 19.1 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 EAU85278.2 - 1.6e-16 59.9 7.8 7.3e-05 23.0 0.0 8.1 9 0 0 9 9 9 5 Ankyrin repeat TAP_C PF03943.13 EAU85279.2 - 2e-11 43.3 0.0 4.9e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 EAU85279.2 - 1.4e-08 35.3 0.0 0.0024 18.5 0.0 2.3 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 EAU85279.2 - 9.5e-06 25.2 0.5 1.6e-05 24.4 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EAU85279.2 - 0.0085 16.5 7.9 0.04 14.3 4.7 2.9 1 1 2 3 3 3 1 Leucine Rich repeats (2 copies) UBA_4 PF14555.6 EAU85279.2 - 0.096 12.5 0.4 0.24 11.2 0.4 1.7 1 0 0 1 1 1 0 UBA-like domain Herpes_pp85 PF04637.12 EAU85279.2 - 0.096 11.1 1.3 0.16 10.4 1.3 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LRR_8 PF13855.6 EAU85279.2 - 2.1 8.2 6.3 9.3 6.1 6.3 2.2 1 1 0 1 1 1 0 Leucine rich repeat MFS_1 PF07690.16 EAU85281.2 - 1.7e-14 53.6 10.7 2.2e-10 40.0 3.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU85281.2 - 1.5e-07 30.6 0.7 2.8e-07 29.8 0.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EAU85281.2 - 0.014 13.8 0.3 0.02 13.4 0.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EAU85282.2 - 8.3e-24 84.2 25.0 8.3e-24 84.2 25.0 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU85282.2 - 7.5e-09 35.0 2.5 7.5e-09 35.0 2.5 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter PIF1 PF05970.14 EAU85285.2 - 5.2e-24 85.1 0.0 9.2e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU85285.2 - 2.1e-12 47.2 0.0 4.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU85285.2 - 9.8e-10 38.9 0.0 2.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 EAU85285.2 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 EAU85285.2 - 0.01 15.8 0.0 0.038 14.0 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PriA_3primeBD PF17764.1 EAU85285.2 - 0.017 15.0 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 3′ DNA-binding domain (3′BD) AAA_11 PF13086.6 EAU85285.2 - 0.13 12.0 3.0 4 7.1 0.0 3.2 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EAU85285.2 - 0.87 10.1 4.8 12 6.4 0.0 3.2 2 1 1 3 3 3 0 AAA domain Packaging_FI PF14000.6 EAU85286.1 - 0.11 12.9 0.4 0.21 12.0 0.4 1.5 1 0 0 1 1 1 0 DNA packaging protein FI DUF2192 PF09958.9 EAU85287.2 - 0.039 13.5 0.1 0.64 9.5 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2192) Intein_splicing PF14890.6 EAU85287.2 - 0.12 12.3 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Intein splicing domain DUF4589 PF15252.6 EAU85288.2 - 0.038 14.0 2.3 0.064 13.3 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) Cyclin_N PF00134.23 EAU85289.2 - 4.4e-12 45.9 0.0 6.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain APG6_N PF17675.1 EAU85290.2 - 0.85 10.2 18.7 1.1 9.7 18.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 EAU85290.2 - 0.89 9.6 10.4 1.2 9.2 10.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Casc1_N PF15927.5 EAU85290.2 - 1.9 8.1 25.0 3.2 7.4 25.0 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MCPVI PF02993.14 EAU85290.2 - 3.3 7.5 10.5 0.096 12.5 4.5 1.5 2 0 0 2 2 2 0 Minor capsid protein VI F-box-like PF12937.7 EAU85298.1 - 6.2e-09 35.6 0.8 1.3e-08 34.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85298.1 - 0.001 18.9 0.0 0.0038 17.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain Cation_ATPase_C PF00689.21 EAU85299.1 - 3.5e-45 153.9 5.5 3.5e-45 153.9 5.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EAU85299.1 - 3.6e-33 114.6 0.1 3.6e-33 114.6 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAU85299.1 - 3e-21 75.3 0.0 7e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAU85299.1 - 7.1e-15 55.9 0.2 2.7e-14 54.0 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAU85299.1 - 9.7e-08 31.6 0.1 4.7e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAU85299.1 - 0.00051 19.8 0.2 0.0095 15.7 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AP3D1 PF06375.11 EAU85299.1 - 0.031 14.5 4.5 0.065 13.5 4.5 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Glyco_transf_20 PF00982.21 EAU85301.2 - 3.5e-188 626.1 0.0 3.5e-187 622.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 EAU85301.2 - 0.00028 21.3 0.0 0.00052 20.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EAU85301.2 - 0.099 12.2 0.1 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Ribosomal_L10 PF00466.20 EAU85302.2 - 4.2e-25 87.8 0.5 8.8e-25 86.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EAU85302.2 - 5.6e-21 74.3 0.0 1.1e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EAU85302.2 - 1.4e-15 57.7 20.0 7.3e-15 55.3 16.0 3.2 2 1 0 2 2 2 1 60s Acidic ribosomal protein AA_permease_2 PF13520.6 EAU85304.1 - 2.1e-71 241.0 43.4 2.6e-71 240.7 43.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAU85304.1 - 2.4e-18 66.0 36.1 3.4e-18 65.5 36.1 1.2 1 0 0 1 1 1 1 Amino acid permease MtrF PF09472.10 EAU85304.1 - 1.5 8.2 6.4 0.82 9.1 0.6 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) zf-C3HC PF07967.13 EAU85305.1 - 2.2e-13 50.4 1.4 4.3e-06 26.8 0.0 4.0 3 2 1 4 4 4 3 C3HC zinc finger-like Rsm1 PF08600.10 EAU85305.1 - 3.1e-12 46.5 0.0 7.2e-10 38.9 0.0 3.0 3 0 0 3 3 3 1 Rsm1-like DM PF00751.18 EAU85305.1 - 0.12 12.3 2.3 7.7 6.5 0.6 2.5 2 0 0 2 2 2 0 DM DNA binding domain DEAD PF00270.29 EAU85306.2 - 1.1e-38 132.8 0.0 2.6e-38 131.5 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU85306.2 - 2.3e-22 79.4 0.0 1.5e-21 76.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU85306.2 - 1.6e-08 34.7 0.0 4.6e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EAU85306.2 - 0.032 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_19 PF13245.6 EAU85306.2 - 0.045 14.1 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU85306.2 - 0.2 11.9 0.7 4.4 7.6 0.8 2.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EAU85307.1 - 2.4e-35 121.9 0.1 3.9e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU85307.1 - 6.9e-28 97.2 0.2 2e-27 95.8 0.1 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAU85307.1 - 0.0037 17.6 0.7 0.089 13.1 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU85307.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EAU85308.2 - 8.3e-18 64.4 4.2 0.0034 18.2 0.0 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU85308.2 - 3.1e-12 46.6 0.0 7.4e-06 26.2 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU85308.2 - 0.0015 17.5 0.1 0.58 9.1 0.0 3.0 2 2 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAU85308.2 - 0.0096 15.8 0.0 0.39 10.6 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EAU85308.2 - 0.031 13.0 0.0 1.1 8.0 0.0 3.0 2 1 0 3 3 3 0 Nup133 N terminal like F-box-like PF12937.7 EAU85309.2 - 2.7e-09 36.8 0.1 6.4e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85309.2 - 7.5e-08 32.1 0.0 2.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain DnaJ_C PF01556.18 EAU85313.2 - 5.5e-32 110.9 0.1 8.2e-32 110.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAU85313.2 - 1e-14 54.4 0.4 1.8e-14 53.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAU85313.2 - 8.9e-14 51.6 16.8 1.4e-13 50.9 16.8 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EAU85313.2 - 0.00025 21.0 5.1 0.2 11.7 1.3 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_6 PF14599.6 EAU85313.2 - 0.017 15.1 1.0 0.017 15.1 1.0 2.5 2 0 0 2 2 2 0 Zinc-ribbon Anti-TRAP PF15777.5 EAU85313.2 - 0.12 12.3 8.9 0.41 10.6 1.9 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EAU85313.2 - 1.7 8.3 6.9 0.26 10.9 0.7 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 EAU85313.2 - 2.1 8.4 6.8 2.7 8.1 1.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 EAU85313.2 - 6.2 7.0 7.7 4.9 7.4 4.9 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 Asp PF00026.23 EAU85315.2 - 2.2e-44 152.2 0.0 3.1e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU85315.2 - 3e-09 37.4 0.3 1.1e-07 32.3 0.3 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RasGAP PF00616.19 EAU85316.1 - 4.1e-59 199.8 0.3 3.3e-58 196.8 0.0 2.4 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EAU85316.1 - 6.2e-38 130.0 0.4 6.2e-38 130.0 0.4 2.0 2 0 0 2 2 2 1 RasGAP C-terminus YabA PF06156.13 EAU85316.1 - 0.34 11.6 2.7 42 4.8 0.4 3.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF4047 PF13256.6 EAU85316.1 - 1.3 9.2 4.6 0.37 11.0 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) BRO1 PF03097.18 EAU85318.2 - 7.8e-105 350.8 0.0 1.5e-104 349.9 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EAU85318.2 - 3.4e-73 246.5 12.7 6.1e-73 245.7 12.7 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Tex_N PF09371.10 EAU85318.2 - 1.1 8.9 8.5 0.1 12.2 0.8 2.9 3 0 0 3 3 3 0 Tex-like protein N-terminal domain DUF3421 PF11901.8 EAU85319.1 - 1.3e-33 115.4 0.1 2.9e-33 114.3 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3421) Zip PF02535.22 EAU85319.1 - 0.063 12.5 1.7 0.065 12.4 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 EAU85319.1 - 0.59 10.4 17.4 0.82 10.0 17.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.8 EAU85319.1 - 4.4 6.0 10.9 5.9 5.6 10.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.6 EAU85319.1 - 5.2 6.7 6.7 7.6 6.2 6.7 1.3 1 0 0 1 1 1 0 FAM176 family SpoIIIAH PF12685.7 EAU85319.1 - 5.5 6.8 12.5 7.7 6.3 12.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein WLM PF08325.10 EAU85321.2 - 7.4e-33 114.2 9.0 1.8e-31 109.7 3.3 2.9 2 2 0 2 2 2 1 WLM domain DUF45 PF01863.17 EAU85321.2 - 2.7e-06 27.6 0.4 9.3e-06 25.8 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.18 EAU85321.2 - 4.8e-05 22.6 0.7 8.6e-05 21.8 0.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprT-like PF10263.9 EAU85321.2 - 0.00014 21.7 0.1 0.0008 19.2 0.0 2.1 2 0 0 2 2 2 1 SprT-like family PNISR PF15996.5 EAU85322.1 - 0.81 9.9 47.4 0.15 12.3 30.9 3.2 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR Peptidase_S64 PF08192.11 EAU85322.1 - 2 6.8 13.1 3.4 6.1 13.1 1.3 1 0 0 1 1 1 0 Peptidase family S64 RhoGAP PF00620.27 EAU85323.2 - 2.4e-38 131.4 0.0 3.7e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain GMC_oxred_N PF00732.19 EAU85325.2 - 2.1e-63 214.5 0.0 1.3e-32 113.3 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU85325.2 - 1.5e-35 122.8 0.0 2.9e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EAU85325.2 - 2.3e-06 27.5 0.4 0.00011 22.0 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAU85325.2 - 1.1e-05 24.6 0.1 2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EAU85325.2 - 1.3e-05 24.6 0.0 2.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EAU85325.2 - 2.1e-05 24.7 0.2 9.2e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU85325.2 - 2.2e-05 23.8 0.2 0.0041 16.3 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EAU85325.2 - 0.0038 16.5 0.1 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU85325.2 - 0.0099 14.6 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EAU85325.2 - 0.093 13.3 0.3 0.92 10.1 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAU85325.2 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Exo_endo_phos PF03372.23 EAU85326.2 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2956 PF11169.8 EAU85326.2 - 0.4 10.9 3.8 0.48 10.6 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) DUF3915 PF13054.6 EAU85326.2 - 9.9 6.2 7.1 17 5.4 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GCM PF03615.15 EAU85328.2 - 6.9e-05 22.8 0.9 0.00014 21.8 0.9 1.5 1 0 0 1 1 1 1 GCM motif protein GMC_oxred_N PF00732.19 EAU85330.2 - 4.4e-49 167.5 0.0 2.4e-32 112.5 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU85330.2 - 1e-39 136.3 0.0 1.6e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EAU85330.2 - 2.1e-06 27.0 0.6 3.7e-06 26.2 0.6 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EAU85330.2 - 6.9e-05 22.2 0.1 0.00013 21.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EAU85330.2 - 8e-05 22.8 0.9 0.00019 21.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU85330.2 - 0.00048 19.8 4.0 0.00052 19.7 1.3 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU85330.2 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU85330.2 - 0.0021 17.2 1.6 0.0021 17.2 1.6 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EAU85330.2 - 0.011 14.4 0.3 0.016 13.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EAU85330.2 - 0.087 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EAU85330.2 - 0.22 10.7 0.3 0.37 10.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Drf_GBD PF06371.13 EAU85331.2 - 6.6e-14 51.9 0.0 5.2e-10 39.2 0.1 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Glyco_hydro_17 PF00332.18 EAU85332.2 - 4.3e-15 56.1 0.7 3.8e-12 46.4 0.5 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 CwsA PF10814.8 EAU85332.2 - 0.056 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA RNB PF00773.19 EAU85333.1 - 1.4e-46 159.3 0.0 5e-46 157.5 0.0 1.9 1 1 0 1 1 1 1 RNB domain CHGN PF05679.16 EAU85333.1 - 0.2 10.4 0.0 7 5.3 0.0 2.3 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase ABC2_membrane PF01061.24 EAU85334.2 - 2.3e-80 269.0 50.7 1.8e-42 145.1 21.7 3.5 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EAU85334.2 - 8.3e-38 130.0 0.0 1.9e-17 64.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EAU85334.2 - 1.3e-36 124.4 10.3 4.4e-30 103.4 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EAU85334.2 - 1e-19 70.9 0.7 2.2e-19 69.9 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EAU85334.2 - 4.3e-08 32.7 46.9 2.2e-06 27.1 15.5 3.6 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 EAU85334.2 - 1.5e-07 31.9 0.0 0.00021 21.7 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EAU85334.2 - 6.1e-07 29.5 0.0 3.5e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EAU85334.2 - 3.1e-06 26.9 0.0 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU85334.2 - 7.9e-05 23.0 0.0 0.026 14.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAU85334.2 - 0.00047 20.4 0.1 1.1 9.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EAU85334.2 - 0.0017 18.4 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EAU85334.2 - 0.0024 18.4 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU85334.2 - 0.0032 17.4 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 EAU85334.2 - 0.004 16.8 0.5 0.25 11.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EAU85334.2 - 0.0043 17.2 0.1 2.2 8.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EAU85334.2 - 0.0053 16.4 0.1 0.26 10.8 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 EAU85334.2 - 0.0061 16.4 0.0 0.087 12.7 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase SMC_N PF02463.19 EAU85334.2 - 0.0073 15.8 0.0 2.2 7.6 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF3600 PF12207.8 EAU85334.2 - 0.0086 16.0 0.0 4 7.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3600) AAA_21 PF13304.6 EAU85334.2 - 0.012 15.4 0.0 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 EAU85334.2 - 0.038 14.4 0.0 15 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAU85334.2 - 0.039 13.7 0.3 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain DUF4059 PF13268.6 EAU85334.2 - 0.041 14.3 0.9 0.4 11.1 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) TsaE PF02367.17 EAU85334.2 - 0.047 13.7 0.2 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EAU85334.2 - 0.11 12.4 0.0 28 4.6 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EAU85334.2 - 0.12 11.7 0.0 2.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EAU85334.2 - 0.15 12.4 0.4 12 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAU85334.2 - 0.16 12.3 0.0 4.7 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EAU85334.2 - 0.17 12.4 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EAU85334.2 - 0.25 10.6 0.0 9.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Septin p450 PF00067.22 EAU85335.1 - 5.4e-82 276.0 0.0 6.9e-82 275.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EAU85336.1 - 3.7e-09 36.4 0.6 8.7e-09 35.1 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85336.1 - 7.9e-05 22.4 0.5 7.9e-05 22.4 0.5 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EAU85336.1 - 0.17 11.7 0.1 0.62 10.0 0.1 1.9 1 0 0 1 1 1 0 F-box Annexin PF00191.20 EAU85337.2 - 0.02 15.0 0.0 0.81 9.8 0.0 2.4 2 0 0 2 2 2 0 Annexin Adeno_E4 PF05385.11 EAU85338.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Sec3_C PF09763.9 EAU85339.2 - 0.078 11.4 0.1 0.082 11.3 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 B12-binding PF02310.19 EAU85339.2 - 0.15 12.1 0.0 20 5.3 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain SOG2 PF10428.9 EAU85339.2 - 0.19 10.9 7.8 0.23 10.6 7.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EAU85339.2 - 0.36 10.7 4.8 0.44 10.4 4.8 1.1 1 0 0 1 1 1 0 SPX domain MFS_1 PF07690.16 EAU85340.2 - 1.4e-30 106.4 27.4 1.3e-29 103.3 27.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU85340.2 - 8.6e-08 31.5 15.3 1.1e-05 24.5 3.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter NicO PF03824.16 EAU85340.2 - 0.12 11.7 4.9 0.16 11.3 0.6 2.2 2 0 0 2 2 2 0 High-affinity nickel-transport protein MFS_2 PF13347.6 EAU85340.2 - 8.3 4.8 18.6 0.027 13.1 6.1 2.5 3 0 0 3 3 3 0 MFS/sugar transport protein Choline_kin_N PF04428.14 EAU85342.2 - 0.0054 16.4 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 Choline kinase N terminus Pkinase PF00069.25 EAU85342.2 - 0.014 14.7 0.1 0.027 13.8 0.0 1.4 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85342.2 - 0.02 14.2 0.1 0.031 13.6 0.1 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase ATP-synt_J PF04911.12 EAU85342.2 - 0.087 12.4 0.5 7.6 6.2 0.1 2.5 2 0 0 2 2 2 0 ATP synthase j chain SPT2 PF08243.11 EAU85344.1 - 4.8e-18 65.7 17.5 4.8e-18 65.7 17.5 4.1 3 1 0 3 3 3 1 SPT2 chromatin protein Vps51 PF08700.11 EAU85348.1 - 5.8e-24 84.0 0.7 8.7e-24 83.4 0.7 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EAU85348.1 - 0.00033 20.8 3.1 0.00046 20.4 3.1 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 EAU85348.1 - 0.0024 16.6 1.5 0.003 16.3 1.5 1.1 1 0 0 1 1 1 1 Dor1-like family Abhydrolase_1 PF00561.20 EAU85348.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold FlgN PF05130.12 EAU85348.1 - 0.043 14.3 1.2 0.065 13.7 1.2 1.3 1 0 0 1 1 1 0 FlgN protein AAA PF00004.29 EAU85352.1 - 1.8e-42 144.9 0.0 3.1e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EAU85352.1 - 1.6e-10 40.8 0.0 3.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EAU85352.1 - 3.6e-09 36.3 0.3 7.8e-09 35.2 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EAU85352.1 - 3.4e-06 27.3 0.0 7.7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EAU85352.1 - 2.7e-05 24.4 0.2 0.032 14.5 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EAU85352.1 - 3.8e-05 23.7 0.1 0.00018 21.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EAU85352.1 - 5.7e-05 22.4 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EAU85352.1 - 0.00024 21.6 0.2 0.011 16.1 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EAU85352.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EAU85352.1 - 0.0057 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAU85352.1 - 0.0083 16.2 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAU85352.1 - 0.0083 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAU85352.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EAU85352.1 - 0.011 15.1 0.2 0.38 10.1 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.6 EAU85352.1 - 0.018 15.6 0.0 0.04 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAU85352.1 - 0.021 15.0 0.3 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EAU85352.1 - 0.031 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 EAU85352.1 - 0.042 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 EAU85352.1 - 0.085 12.6 0.2 0.25 11.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAU85352.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Prot_ATP_OB_N PF17758.1 EAU85352.1 - 0.11 12.1 0.2 0.91 9.2 0.0 2.6 3 0 0 3 3 3 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 EAU85352.1 - 0.13 11.8 0.8 5.4 6.5 0.2 2.4 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EAU85352.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EAU85352.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Med26 PF08711.11 EAU85354.1 - 1.3e-09 37.9 0.0 5e-09 36.0 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TPR_2 PF07719.17 EAU85357.2 - 1.5e-09 37.3 7.4 0.00089 19.2 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAU85357.2 - 5.7e-07 29.1 3.0 0.0072 16.1 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU85357.2 - 0.00013 22.5 0.1 3.5 8.7 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU85357.2 - 0.00027 20.7 0.0 6.2 7.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU85357.2 - 0.00044 20.4 0.6 0.0086 16.3 0.0 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EAU85357.2 - 0.00051 20.3 0.6 0.76 10.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAU85357.2 - 0.0014 19.1 0.6 12 6.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EAU85357.2 - 0.0017 18.5 0.3 0.32 11.4 0.0 3.2 3 0 0 3 3 3 1 PPR repeat TPR_19 PF14559.6 EAU85357.2 - 0.0048 17.4 3.5 0.21 12.1 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU85357.2 - 0.031 14.6 0.2 5 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FANCI_HD2 PF14680.6 EAU85357.2 - 0.036 13.3 0.1 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 FANCI helical domain 2 BTAD PF03704.17 EAU85357.2 - 0.065 13.7 0.8 19 5.6 0.0 2.9 2 1 0 2 2 2 0 Bacterial transcriptional activator domain DUF5113 PF17140.4 EAU85357.2 - 0.07 12.9 0.2 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) DUF3087 PF11286.8 EAU85357.2 - 0.12 11.9 0.1 0.22 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3087) TPR_11 PF13414.6 EAU85357.2 - 0.12 12.1 1.4 5.1 6.9 0.0 3.0 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.6 EAU85357.2 - 4 7.9 8.1 4.8 7.6 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NMT1 PF09084.11 EAU85358.2 - 0.00027 21.0 0.0 0.00052 20.0 0.0 1.5 1 1 1 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.7 EAU85358.2 - 0.00039 20.1 0.0 0.00052 19.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 EAU85358.2 - 0.0057 16.1 0.0 0.008 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 GSHPx PF00255.19 EAU85361.2 - 1.8e-15 56.5 0.0 5.5e-12 45.2 0.0 2.2 1 1 1 2 2 2 2 Glutathione peroxidase Ral PF11058.8 EAU85361.2 - 0.037 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein Ral Baculo_LEF-3 PF05847.11 EAU85361.2 - 0.1 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) ACBP PF00887.19 EAU85363.1 - 4.2e-27 94.2 0.1 6.2e-27 93.6 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.29 EAU85364.1 - 4.8e-35 120.2 0.5 2.3e-19 69.9 0.2 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 EAU85364.1 - 1.6e-12 47.8 10.0 1.5e-06 28.6 3.6 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 EAU85364.1 - 3.2e-12 46.5 0.0 1.6e-06 28.2 0.0 3.3 3 0 0 3 3 3 2 PH domain PH_8 PF15409.6 EAU85364.1 - 2.2e-06 27.9 0.4 0.00035 20.8 0.1 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 EAU85364.1 - 2.8e-05 24.5 0.8 0.0087 16.4 0.3 3.4 2 2 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 EAU85364.1 - 0.0021 17.9 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 EAU85364.1 - 0.01 16.0 0.2 3.1 7.9 0.3 2.8 2 1 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.6 EAU85364.1 - 0.04 13.7 0.0 0.35 10.6 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 EAU85365.2 - 9e-26 90.6 0.0 1.2e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU85365.2 - 0.00013 22.0 9.1 0.00027 21.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EAU85366.2 - 3.5e-46 157.7 1.1 4.4e-46 157.4 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU85366.2 - 0.00032 20.7 10.3 0.0006 19.9 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VTC PF09359.10 EAU85368.2 - 3.8e-94 315.1 0.0 7.4e-94 314.2 0.0 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EAU85368.2 - 3.7e-17 63.3 20.9 4e-09 36.9 2.8 3.4 2 1 0 3 3 3 3 SPX domain DUF202 PF02656.15 EAU85368.2 - 4.5e-08 33.4 3.5 9.3e-08 32.4 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Mak16 PF04874.14 EAU85368.2 - 0.0034 17.9 1.1 0.0034 17.9 1.1 2.9 3 0 0 3 3 3 1 Mak16 protein C-terminal region Clc-like PF07062.12 EAU85368.2 - 0.21 11.0 0.8 0.41 10.1 0.8 1.4 1 0 0 1 1 1 0 Clc-like Gtr1_RagA PF04670.12 EAU85369.2 - 6.8e-44 150.0 0.1 9.9e-44 149.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU85369.2 - 3.5e-05 23.8 0.0 7.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EAU85369.2 - 0.00039 19.9 0.1 0.0006 19.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAU85369.2 - 0.0006 20.0 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EAU85369.2 - 0.0074 16.3 0.2 0.022 14.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.10 EAU85369.2 - 0.035 13.6 0.1 0.085 12.3 0.1 1.6 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EAU85369.2 - 0.039 14.3 0.0 0.067 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 EAU85369.2 - 0.072 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Ras family DUF1729 PF08354.10 EAU85370.1 - 5.8e-152 505.6 0.0 1.1e-151 504.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Fas_alpha_ACP PF18325.1 EAU85370.1 - 2.3e-75 252.4 0.0 2e-74 249.3 0.0 2.5 3 0 0 3 3 2 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 EAU85370.1 - 7.6e-74 249.1 0.0 3e-71 240.5 0.0 3.4 3 0 0 3 3 3 1 Acyl transferase domain FAS_I_H PF18314.1 EAU85370.1 - 5.2e-71 238.5 0.1 1e-70 237.5 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain FAS_meander PF17951.1 EAU85370.1 - 3.8e-45 153.3 0.0 1.8e-44 151.1 0.0 2.1 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 EAU85370.1 - 7e-35 120.9 0.0 1.7e-34 119.7 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EAU85370.1 - 1.6e-25 89.1 0.0 5.2e-25 87.4 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.26 EAU85370.1 - 5.4e-25 88.4 0.7 1.1e-24 87.5 0.7 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_N PF17828.1 EAU85370.1 - 1.1e-24 86.9 0.3 2e-24 86.0 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EAU85370.1 - 1.3e-15 57.7 0.0 1.3e-14 54.5 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ACPS PF01648.20 EAU85370.1 - 2.8e-15 56.4 0.0 6.7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EAU85370.1 - 3.7e-15 56.0 0.0 8.5e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EAU85370.1 - 9.1e-09 35.1 0.0 5.1e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU85370.1 - 4.4e-07 29.7 0.0 3.3e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase IucA_IucC PF04183.12 EAU85373.2 - 4.7e-29 101.6 0.0 1.2e-28 100.4 0.1 1.6 2 0 0 2 2 2 1 IucA / IucC family FhuF PF06276.12 EAU85373.2 - 3.9e-12 46.9 0.1 9.5e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter FhuF PF06276.12 EAU85374.2 - 1.8e-13 51.2 0.3 3.1e-13 50.4 0.3 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 EAU85374.2 - 1.2e-12 47.9 0.1 1.1e-09 38.3 0.0 2.2 2 0 0 2 2 2 2 IucA / IucC family C2 PF00168.30 EAU85375.2 - 3.2e-17 62.7 0.1 5e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 C2 domain Frag1 PF10277.9 EAU85376.2 - 1.7e-36 125.9 19.1 8.4e-24 84.3 9.1 2.0 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family Voltage_CLC PF00654.20 EAU85376.2 - 0.0083 15.4 4.1 0.012 14.9 4.1 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel MIG-14_Wnt-bd PF06664.12 EAU85376.2 - 0.095 11.9 8.3 0.016 14.5 4.2 1.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion NEMP PF10225.9 EAU85376.2 - 0.11 12.2 6.9 0.17 11.5 6.9 1.3 1 0 0 1 1 1 0 NEMP family PalH PF08733.10 EAU85376.2 - 0.12 11.3 7.1 0.19 10.7 7.0 1.4 1 1 0 1 1 1 0 PalH/RIM21 DUF2070 PF09843.9 EAU85376.2 - 7.3 4.7 9.2 9.2 4.4 9.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DSBA PF01323.20 EAU85377.1 - 1.4e-26 93.4 0.0 1.8e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EAU85377.1 - 0.0056 16.7 0.1 0.1 12.7 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin domain Lsr2 PF11774.8 EAU85377.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Lsr2 Thioredoxin_5 PF13743.6 EAU85377.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin F-box-like PF12937.7 EAU85378.2 - 8.1e-10 38.4 1.7 1.9e-09 37.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.13 EAU85378.2 - 0.015 15.9 0.4 3.1 8.6 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat F-box PF00646.33 EAU85378.2 - 0.23 11.4 0.1 0.23 11.4 0.1 2.3 2 1 0 2 2 2 0 F-box domain SART-1 PF03343.13 EAU85380.2 - 5.1e-159 530.8 71.2 5.1e-159 530.8 71.2 1.9 1 1 1 2 2 2 1 SART-1 family DDE_Tnp_4 PF13359.6 EAU85380.2 - 0.044 13.4 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 DDE superfamily endonuclease IclR PF01614.18 EAU85380.2 - 0.1 12.4 0.6 0.8 9.5 0.1 2.5 2 0 0 2 2 2 0 Bacterial transcriptional regulator Arg_tRNA_synt_N PF03485.16 EAU85380.2 - 0.41 11.3 2.9 3 8.5 0.2 3.0 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain RNase_HII PF01351.18 EAU85381.1 - 6.2e-50 169.8 0.0 8.6e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII TFIIS_C PF01096.18 EAU85382.2 - 1.1e-13 50.8 1.6 1.1e-13 50.8 1.6 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EAU85382.2 - 4.4e-10 39.3 4.2 4.4e-10 39.3 4.2 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.6 EAU85382.2 - 0.0077 16.7 4.1 0.56 10.8 0.4 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 EAU85382.2 - 0.012 16.0 0.6 0.012 16.0 0.6 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar C1_1 PF00130.22 EAU85382.2 - 0.033 14.1 0.6 0.033 14.1 0.6 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 EAU85382.2 - 0.082 12.5 9.2 3 7.5 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 EAU85382.2 - 0.095 12.7 10.0 1.5 8.9 1.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon CpXC PF14353.6 EAU85382.2 - 0.12 12.4 4.5 4.6 7.3 1.3 2.7 2 1 0 2 2 2 0 CpXC protein UPF0547 PF10571.9 EAU85382.2 - 0.31 11.1 11.9 1.4 9.1 0.1 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 EAU85382.2 - 0.63 9.8 8.0 0.87 9.4 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-RRN7 PF11781.8 EAU85382.2 - 0.71 9.6 7.8 6.4 6.5 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 EAU85382.2 - 0.97 9.6 11.7 3.8 7.7 0.2 3.6 3 1 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.13 EAU85382.2 - 1.6 8.5 7.6 0.21 11.3 0.5 2.5 2 1 0 2 2 2 0 InsA N-terminal domain DUF3268 PF11672.8 EAU85382.2 - 1.8 8.9 5.6 0.91 9.9 0.6 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain Elf1 PF05129.13 EAU85382.2 - 1.9 8.6 9.1 1.2 9.3 1.1 2.6 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like zf-IS66 PF13005.7 EAU85382.2 - 2.4 8.6 8.6 7.1 7.1 0.0 3.4 3 1 1 4 4 3 0 zinc-finger binding domain of transposase IS66 zinc_ribbon_10 PF10058.9 EAU85382.2 - 5.1 6.9 11.1 2 8.2 2.2 3.0 2 2 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2387 PF09526.10 EAU85382.2 - 5.2 7.3 7.6 0.56 10.4 1.1 2.4 2 2 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc-ribbons_6 PF07191.12 EAU85382.2 - 5.9 7.0 12.0 9.2 6.3 1.0 3.0 2 2 0 2 2 2 0 zinc-ribbons RecR PF02132.15 EAU85382.2 - 6.9 6.3 11.7 0.25 10.9 1.4 3.0 3 1 0 3 3 3 0 RecR protein Zn_Tnp_IS1595 PF12760.7 EAU85382.2 - 9.1 6.4 11.6 0.11 12.5 1.3 2.6 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_S27e PF01667.17 EAU85382.2 - 9.4 6.0 9.1 1.7 8.4 1.5 3.2 2 2 0 2 2 2 0 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EAU85382.2 - 9.7 5.8 11.4 5.5 6.6 0.1 3.6 4 0 0 4 4 4 0 TFIIB zinc-binding LsmAD PF06741.13 EAU85383.2 - 7.3e-29 100.1 0.1 1.8e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 EAU85383.2 - 9.2e-06 25.7 0.1 1.8e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Sun2_CC2 PF18580.1 EAU85383.2 - 0.085 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 Mad3_BUB1_I PF08311.12 EAU85384.1 - 3.5e-36 123.9 4.3 6.3e-36 123.1 4.3 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EAU85384.1 - 1.3e-11 44.3 0.0 8.4e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 EAU85384.1 - 2.2e-07 31.0 0.3 7.7e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 EAU85384.1 - 5.4e-07 29.2 0.0 8.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 EAU85384.1 - 9.6e-07 28.9 0.2 6.4e-06 26.2 0.0 2.5 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Kdo PF06293.14 EAU85384.1 - 0.09 12.1 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CENP-F_N PF10481.9 EAU85385.2 - 0.015 15.0 1.3 0.035 13.7 1.3 1.6 1 0 0 1 1 1 0 Cenp-F N-terminal domain Acetyltransf_3 PF13302.7 EAU85386.1 - 5.2e-09 36.9 0.0 6.5e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU85386.1 - 0.00052 20.2 0.0 0.00077 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HicA_toxin PF07927.12 EAU85388.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.0 2 0 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Sugar_tr PF00083.24 EAU85390.1 - 3.5e-68 230.5 25.9 1.4e-48 165.9 2.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAU85390.1 - 1.6e-17 63.5 41.5 3.5e-15 55.8 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MGC-24 PF05283.11 EAU85391.2 - 6.2 7.3 11.0 0.79 10.2 7.1 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Exo_endo_phos PF03372.23 EAU85392.2 - 3.9e-09 36.4 0.0 6.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thioredoxin PF00085.20 EAU85393.2 - 1.2e-36 124.8 0.1 2e-18 66.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EAU85393.2 - 7.6e-23 81.2 3.9 1.9e-22 80.0 3.1 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EAU85393.2 - 4.6e-12 45.9 0.0 9.7e-06 25.1 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 EAU85393.2 - 3.8e-05 23.7 0.0 0.02 14.8 0.0 3.2 1 1 2 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EAU85393.2 - 0.00017 22.0 0.3 0.14 12.6 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.11 EAU85393.2 - 0.011 15.7 0.0 7.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EAU85393.2 - 0.014 15.3 0.0 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 AhpC/TSA family WD40 PF00400.32 EAU85394.1 - 8.2e-33 111.9 21.3 1.7e-08 34.9 0.3 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU85394.1 - 5.8e-14 52.2 0.1 1.3e-05 25.4 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU85394.1 - 2.1e-05 23.6 0.0 0.19 10.7 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EAU85394.1 - 0.00045 19.9 1.1 0.009 15.6 0.1 2.5 1 1 0 2 2 2 1 PQQ-like domain WD40_like PF17005.5 EAU85394.1 - 0.0055 16.1 0.0 7.1 5.9 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 EAU85394.1 - 0.17 10.5 0.0 0.68 8.5 0.0 1.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EAU85394.1 - 0.29 11.1 1.9 8.5 6.5 0.0 3.0 2 1 0 2 2 2 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 EAU85394.1 - 0.32 9.3 0.0 14 3.8 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Lipase_3 PF01764.25 EAU85395.2 - 1.3e-06 28.3 0.0 4.4e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 EAU85395.2 - 0.2 11.6 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 EAU85395.2 - 0.23 11.1 0.0 0.46 10.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EAU85395.2 - 2.3 8.7 5.9 0.43 11.2 1.1 2.1 2 2 0 2 2 2 0 Alpha/beta hydrolase family Trehalase PF01204.18 EAU85396.2 - 3.2e-167 557.4 0.0 4e-167 557.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EAU85396.2 - 3e-14 52.4 0.1 5e-14 51.7 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF155 PF02582.14 EAU85397.2 - 4.8e-49 166.8 0.0 8.6e-49 166.0 0.0 1.4 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Glutaredoxin2_C PF04399.13 EAU85397.2 - 0.091 12.6 0.1 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain RhoGEF PF00621.20 EAU85398.2 - 7.7e-32 111.0 0.1 1.2e-31 110.3 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 EAU85398.2 - 4.2e-17 62.7 0.0 9.2e-17 61.5 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH PF00169.29 EAU85398.2 - 0.047 14.2 0.0 0.093 13.3 0.0 1.5 1 0 0 1 1 1 0 PH domain PH_16 PF17838.1 EAU85398.2 - 0.12 12.2 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 PH domain eIF-6 PF01912.18 EAU85399.1 - 1.3e-84 282.6 0.3 1.3e-84 282.6 0.3 1.6 2 0 0 2 2 2 1 eIF-6 family Methyltransf_28 PF02636.17 EAU85400.2 - 8.3e-63 212.5 0.0 1e-62 212.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ctf8 PF09696.10 EAU85403.1 - 9.5e-16 58.4 0.1 1.8e-14 54.3 0.1 2.0 1 1 0 1 1 1 1 Ctf8 AhpC-TSA_2 PF13911.6 EAU85404.2 - 1.8e-15 57.0 0.0 3.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EAU85404.2 - 1.4e-05 25.0 0.0 0.00026 20.9 0.0 2.4 1 1 0 1 1 1 1 AhpC/TSA family Avidin PF01382.17 EAU85404.2 - 0.0051 17.3 0.1 0.01 16.3 0.1 1.4 1 0 0 1 1 1 1 Avidin family LPD5 PF18799.1 EAU85404.2 - 0.024 15.0 0.2 0.048 14.1 0.2 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 Redoxin PF08534.10 EAU85404.2 - 0.029 14.1 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Redoxin PTPlike_phytase PF14566.6 EAU85408.2 - 4.7e-142 468.6 0.0 1e-48 165.4 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 EAU85408.2 - 0.00032 20.5 0.0 0.17 11.7 0.0 3.3 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAU85408.2 - 0.0015 18.1 0.2 0.25 10.9 0.1 3.4 3 1 0 3 3 3 1 Protein-tyrosine phosphatase Cnn_1N PF07989.11 EAU85408.2 - 0.18 12.0 0.7 15 5.8 0.1 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 SIR2 PF02146.17 EAU85410.2 - 2.4e-32 112.3 0.0 1.3e-21 77.3 0.0 2.6 2 0 0 2 2 2 2 Sir2 family Trm112p PF03966.16 EAU85410.2 - 0.01 16.4 0.1 0.027 15.0 0.1 1.7 1 0 0 1 1 1 0 Trm112p-like protein TPP_enzyme_M PF00205.22 EAU85410.2 - 0.045 13.5 0.1 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain 6PF2K PF01591.18 EAU85412.2 - 1e-68 231.0 0.0 1.4e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EAU85412.2 - 1.5e-37 129.2 0.0 3.8e-37 127.9 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EAU85412.2 - 5e-05 23.5 0.0 9.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EAU85412.2 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Pkinase PF00069.25 EAU85414.2 - 3.7e-16 59.3 0.0 4.8e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU85414.2 - 3.7e-08 32.5 0.0 6.5e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EAU85414.2 - 1.7e-05 24.3 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3915 PF13054.6 EAU85414.2 - 0.021 14.8 2.7 0.047 13.7 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) MAP65_ASE1 PF03999.12 EAU85414.2 - 10 4.7 5.8 14 4.2 5.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ADH_N_2 PF16884.5 EAU85415.1 - 9e-28 96.3 0.0 1.4e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EAU85415.1 - 1.7e-17 63.6 0.0 3.5e-17 62.6 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU85415.1 - 8.3e-08 33.4 0.0 1.4e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2207 PF09972.9 EAU85416.2 - 0.13 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CE2_N PF17996.1 EAU85417.1 - 0.012 15.6 0.1 0.046 13.7 0.1 1.8 1 1 0 1 1 1 0 Carbohydrate esterase 2 N-terminal Con-6 PF10346.9 EAU85418.1 - 1e-31 108.6 1.4 1.1e-14 54.2 0.0 2.5 2 0 0 2 2 2 2 Conidiation protein 6 Phage_holin_3_6 PF07332.11 EAU85419.2 - 0.5 10.4 5.7 1.3 9.1 5.7 1.6 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Guanylate_cyc_2 PF09778.9 EAU85420.2 - 0.049 13.0 0.6 0.11 11.8 0.2 1.8 2 0 0 2 2 2 0 Guanylylate cyclase ColG_sub PF18496.1 EAU85420.2 - 0.24 11.6 0.1 0.24 11.6 0.1 2.3 2 1 1 3 3 3 0 Collagenase G catalytic helper subdomain DUF5333 PF17267.2 EAU85420.2 - 3.5 7.8 6.5 0.24 11.6 0.4 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5333) Spore_YhcN_YlaJ PF09580.10 EAU85420.2 - 4.6 7.3 9.2 11 6.1 9.2 1.7 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF737 PF05300.11 EAU85421.2 - 0.016 15.6 5.6 0.038 14.3 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DRY_EERY PF09750.9 EAU85421.2 - 0.11 12.7 5.9 0.2 11.9 5.9 1.4 1 0 0 1 1 1 0 Alternative splicing regulator Herpes_DNAp_acc PF04929.12 EAU85421.2 - 0.87 8.5 4.4 1.4 7.8 4.4 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor F-box-like PF12937.7 EAU85425.2 - 1.2e-08 34.7 1.1 3.8e-08 33.1 1.1 2.0 1 0 0 1 1 1 1 F-box-like SGL PF08450.12 EAU85427.2 - 9.6e-05 22.1 0.0 0.00049 19.8 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EAU85427.2 - 0.00073 19.7 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 2 Arylesterase Lactonase PF10282.9 EAU85427.2 - 0.01 15.1 0.0 0.066 12.5 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Str_synth PF03088.16 EAU85427.2 - 0.15 12.2 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase DUF2530 PF10745.9 EAU85428.2 - 7.2 6.9 6.1 7.9 6.8 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Xpo1 PF08389.12 EAU85429.2 - 1.4e-20 73.9 0.1 3.4e-19 69.4 0.0 3.4 4 1 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.22 EAU85429.2 - 0.076 13.3 0.6 8.9 6.9 0.2 4.0 3 0 0 3 3 3 0 HEAT repeat WD40 PF00400.32 EAU85430.1 - 1.3e-19 70.2 6.2 0.00011 22.9 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU85430.1 - 2.4e-10 40.6 0.0 4.1e-06 27.0 0.0 4.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAU85430.1 - 0.00076 19.4 0.1 0.66 9.8 0.0 3.2 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EAU85430.1 - 0.0028 17.0 0.0 0.1 11.9 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EAU85430.1 - 0.027 13.5 0.1 0.49 9.3 0.0 2.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein p450 PF00067.22 EAU85431.2 - 3.7e-48 164.4 0.0 4.8e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.13 EAU85433.2 - 2e-24 86.5 25.5 7.6e-24 84.6 21.6 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF1295 PF06966.12 EAU85434.2 - 6.8e-43 146.9 0.2 9.1e-43 146.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 EAU85434.2 - 1.5e-05 23.9 0.0 2.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 EAU85434.2 - 0.0002 21.7 1.0 0.00028 21.2 0.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EAU85434.2 - 0.00034 21.0 0.0 0.001 19.4 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EAU85434.2 - 0.0086 16.1 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Glyco_hydro_7 PF00840.20 EAU85436.1 - 3.1e-207 688.5 6.5 3.5e-207 688.3 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 EAU85437.1 - 2.1e-207 689.1 6.7 2.4e-207 688.9 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 EAU85438.2 - 6.4e-207 687.5 8.3 7.2e-207 687.3 8.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 UPRTase PF14681.6 EAU85440.1 - 1.3e-45 155.4 0.0 1.5e-43 148.6 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase PRK PF00485.18 EAU85440.1 - 3.9e-38 131.2 0.0 6.8e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 EAU85440.1 - 0.18 12.2 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_C14 PF00656.22 EAU85441.2 - 3.2e-64 217.3 0.0 3.8e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Sugar_tr PF00083.24 EAU85443.2 - 4.5e-114 381.8 19.9 5.9e-114 381.4 19.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU85443.2 - 1.4e-28 99.9 63.0 4.4e-23 81.8 27.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Isochorismatase PF00857.20 EAU85444.2 - 9.6e-16 58.4 0.0 1.2e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family COX5B PF01215.19 EAU85445.1 - 1.5e-49 166.9 0.0 1.8e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EAU85445.1 - 0.011 15.7 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger domain Collagen PF01391.18 EAU85447.1 - 1.1e-05 25.1 18.4 1.1e-05 25.1 18.4 2.7 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) FAD_binding_4 PF01565.23 EAU85448.2 - 2.6e-23 82.3 0.1 4.5e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU85448.2 - 1e-13 51.1 0.2 2.1e-13 50.1 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like CIA30 PF08547.12 EAU85450.1 - 1.6e-25 90.0 0.0 2e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) IMS PF00817.20 EAU85452.2 - 1.9e-36 125.3 0.0 3.6e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EAU85452.2 - 8.7e-15 55.5 0.0 9.5e-14 52.1 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EAU85452.2 - 2.3e-08 33.5 6.2 3.9e-05 23.1 2.7 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Mub_B2 PF17966.1 EAU85452.2 - 0.012 16.4 0.1 0.029 15.1 0.1 1.6 1 0 0 1 1 1 0 Mub B2-like domain IMS_HHH PF11798.8 EAU85452.2 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Pyr_redox_2 PF07992.14 EAU85453.1 - 1.3e-50 172.3 2.0 1.6e-50 172.0 2.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EAU85453.1 - 6.4e-18 64.5 0.0 1.5e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EAU85453.1 - 2.1e-10 41.0 0.2 2.1e-10 41.0 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU85453.1 - 4e-09 36.2 0.2 1e-08 34.8 0.1 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EAU85453.1 - 8.1e-08 32.7 0.0 2.5e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 EAU85453.1 - 1.9e-06 27.7 0.0 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.6 EAU85453.1 - 0.00076 18.7 0.0 0.15 11.2 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1295 PF06966.12 EAU85454.1 - 4e-33 114.9 10.4 1.6e-31 109.7 8.4 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1295) Metallophos PF00149.28 EAU85455.2 - 9.3e-10 39.3 0.3 2e-09 38.3 0.3 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU85455.2 - 5.1e-07 30.0 0.0 1.2e-06 28.8 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EAU85455.2 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Glyco_hydro_7 PF00840.20 EAU85456.2 - 3.2e-203 675.3 7.6 3.6e-203 675.1 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fungal_trans PF04082.18 EAU85461.2 - 5.1e-14 51.9 0.1 7.4e-14 51.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE_assoc PF09335.11 EAU85462.2 - 1.6e-11 44.7 4.4 1.6e-11 44.7 4.4 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein ARID PF01388.21 EAU85463.2 - 8.7e-14 52.0 0.0 2.4e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.12 EAU85463.2 - 9.8e-05 22.6 3.0 0.00012 22.3 0.1 2.7 2 1 0 2 2 2 1 Mediator complex subunit 15 DUF572 PF04502.13 EAU85464.2 - 1.9e-48 165.8 1.0 2.5e-48 165.4 1.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Chitin_bind_4 PF00379.23 EAU85464.2 - 0.33 11.5 2.9 12 6.5 0.2 3.0 3 0 0 3 3 3 0 Insect cuticle protein Pkinase PF00069.25 EAU85469.1 - 1.1e-41 142.9 0.0 1.4e-23 83.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85469.1 - 2.1e-20 73.1 0.0 5.5e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAU85469.1 - 4e-06 26.4 0.0 0.0047 16.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EAU85469.1 - 0.0035 17.3 0.3 0.024 14.6 0.2 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family MIF4G PF02854.19 EAU85470.2 - 2.4e-26 92.7 1.9 2.4e-26 92.7 1.9 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 EAU85470.2 - 1.3e-22 79.9 0.0 5e-22 78.0 0.0 2.1 1 1 0 1 1 1 1 MA3 domain Pox_P35 PF03213.14 EAU85470.2 - 0.096 11.9 0.6 0.28 10.4 0.1 1.9 2 0 0 2 2 2 0 Poxvirus P35 protein Ion_trans PF00520.31 EAU85471.1 - 0.003 16.8 22.8 0.0062 15.8 22.8 1.5 1 1 0 1 1 1 1 Ion transport protein YccJ PF13993.6 EAU85471.1 - 0.14 12.5 0.3 0.38 11.1 0.3 1.7 1 0 0 1 1 1 0 YccJ-like protein AzlD PF05437.12 EAU85471.1 - 3.6 7.8 14.1 12 6.2 3.7 3.6 2 1 1 3 3 3 0 Branched-chain amino acid transport protein (AzlD) Pkinase PF00069.25 EAU85472.2 - 1.9e-63 214.3 0.1 3.6e-63 213.4 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85472.2 - 3.3e-32 111.8 0.0 4.7e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU85472.2 - 3.9e-08 32.9 0.0 1.2e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAU85472.2 - 2.2e-05 23.4 0.0 4.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAU85472.2 - 0.0025 17.2 0.1 0.0069 15.8 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU85472.2 - 0.0042 17.0 0.3 0.0082 16.1 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAU85472.2 - 0.18 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Macro PF01661.21 EAU85473.2 - 2e-40 137.5 0.2 2.9e-40 137.0 0.2 1.2 1 0 0 1 1 1 1 Macro domain PTS_2-RNA PF01885.16 EAU85474.2 - 1.8e-16 60.7 0.0 6e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family RMI1_N PF08585.12 EAU85475.2 - 1.8e-28 99.8 0.0 1.8e-28 99.8 0.0 2.7 4 0 0 4 4 4 1 RecQ mediated genome instability protein TPR_19 PF14559.6 EAU85476.1 - 9.3e-14 51.7 5.8 5.9e-06 26.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU85476.1 - 1.2e-09 38.6 0.1 1.6e-05 25.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU85476.1 - 1.9e-09 37.6 0.1 0.00058 20.0 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EAU85476.1 - 3.2e-09 36.2 2.9 0.33 11.2 0.0 5.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAU85476.1 - 4.5e-08 33.3 7.0 0.2 12.5 0.1 5.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EAU85476.1 - 5.1e-07 29.6 0.2 0.043 14.2 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU85476.1 - 7.2e-07 28.8 1.0 1.3 9.0 0.3 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU85476.1 - 1.9e-05 24.9 2.7 0.32 11.3 0.0 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU85476.1 - 0.00021 21.2 0.8 3.4 8.1 0.0 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAU85476.1 - 0.00022 21.0 0.7 0.79 9.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EAU85476.1 - 0.00067 20.1 0.2 0.0082 16.6 0.1 2.3 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_6 PF13174.6 EAU85476.1 - 0.0022 18.5 5.7 1.3 9.8 0.0 5.0 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 EAU85476.1 - 0.029 14.7 3.0 2.3 8.6 0.2 3.1 3 1 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAU85476.1 - 0.07 13.2 0.5 3.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EAU85476.1 - 0.076 13.7 0.1 3.3 8.6 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat SRF-TF PF00319.18 EAU85476.1 - 0.086 12.3 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) TPR_7 PF13176.6 EAU85476.1 - 0.12 12.5 0.1 17 5.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_43 PF04616.14 EAU85477.2 - 1.4e-64 218.2 1.6 1.8e-64 217.8 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EAU85477.2 - 5.4e-23 81.8 0.0 8e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Svf1_C PF17187.4 EAU85479.2 - 3.7e-46 157.0 0.0 6.3e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EAU85479.2 - 1.7e-45 155.0 0.0 2.5e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Glyco_transf_90 PF05686.12 EAU85480.2 - 8.3e-20 71.0 0.1 2.1e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 Peptidase_M48 PF01435.18 EAU85481.2 - 1.5e-10 41.2 0.0 5.6e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M48 F_bP_aldolase PF01116.20 EAU85482.2 - 3.6e-47 161.2 0.0 6.4e-34 117.7 0.0 2.1 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-II Catalase_C PF18011.1 EAU85482.2 - 0.15 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases Na_Ca_ex PF01699.24 EAU85483.2 - 4.9e-30 104.5 37.6 3.1e-18 66.2 19.2 3.2 3 0 0 3 3 3 3 Sodium/calcium exchanger protein LRR_4 PF12799.7 EAU85484.2 - 0.00086 19.6 6.9 1.4 9.5 0.1 4.9 2 1 5 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU85484.2 - 0.0017 18.2 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EAU85484.2 - 0.0087 16.0 0.9 0.74 10.0 0.1 4.1 3 0 0 3 3 3 1 Leucine Rich repeat Lactococcin PF04369.13 EAU85484.2 - 0.22 11.7 0.9 3 8.0 0.2 2.3 2 0 0 2 2 2 0 Lactococcin-like family Erg28 PF03694.13 EAU85485.1 - 8e-44 148.5 5.6 9.7e-44 148.3 5.6 1.1 1 0 0 1 1 1 1 Erg28 like protein GIIM PF08388.11 EAU85485.1 - 0.00051 20.0 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 Group II intron, maturase-specific domain TPK_catalytic PF04263.16 EAU85487.2 - 8.5e-34 116.2 0.0 2.2e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EAU85487.2 - 1.1e-19 69.9 0.2 2.1e-19 69.0 0.2 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CS PF04969.16 EAU85487.2 - 3.1e-08 34.5 0.0 9.9e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 CS domain Sel1 PF08238.12 EAU85487.2 - 0.0088 16.7 1.7 1.4 9.7 0.1 2.6 2 0 0 2 2 2 2 Sel1 repeat TPR_2 PF07719.17 EAU85487.2 - 0.54 10.5 3.4 2.3 8.6 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4078 PF13300.6 EAU85488.1 - 3.1e-20 72.3 2.9 3.1e-20 72.3 2.9 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF4078) DUF903 PF06004.12 EAU85488.1 - 0.034 14.1 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) DUF4599 PF15371.6 EAU85488.1 - 0.83 10.2 5.5 1.1 9.9 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) LRR_4 PF12799.7 EAU85489.2 - 8.1e-37 124.6 33.0 2.6e-09 37.2 0.8 6.9 3 2 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAU85489.2 - 4.5e-30 103.2 34.6 1.4e-11 44.0 6.4 6.2 2 1 3 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 EAU85489.2 - 1.7e-18 66.8 14.6 2.6e-06 27.1 0.1 3.9 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EAU85489.2 - 1.5e-05 24.9 33.7 8.8 7.3 0.0 10.6 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 EAU85489.2 - 4.6e-05 23.1 29.1 2.1 8.6 0.2 9.2 9 1 2 11 11 11 4 Leucine Rich repeat LRR_5 PF13306.6 EAU85489.2 - 0.034 14.1 0.6 0.5 10.3 0.0 2.3 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) gag_pre-integrs PF13976.6 EAU85489.2 - 0.11 12.4 1.1 0.71 9.8 0.1 2.9 3 1 0 3 3 3 0 GAG-pre-integrase domain DHHW PF14286.6 EAU85489.2 - 3.9 6.7 4.8 5.8 6.1 4.8 1.2 1 0 0 1 1 1 0 DHHW protein GATA PF00320.27 EAU85490.2 - 5.5e-14 51.5 3.9 1.1e-13 50.6 3.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.6 EAU85490.2 - 0.014 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 EAU85490.2 - 0.024 14.9 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold Ank_4 PF13637.6 EAU85491.2 - 0.0013 19.3 0.0 0.84 10.3 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF5610 PF18433.1 EAU85491.2 - 0.069 13.7 0.2 0.11 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5610) Ank_5 PF13857.6 EAU85491.2 - 0.08 13.3 0.1 5.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) MaoC_dehydratas PF01575.19 EAU85494.2 - 7.3e-31 106.3 0.0 1.2e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EAU85494.2 - 5.6e-06 26.5 0.0 5.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 EAU85495.1 - 8e-86 286.5 19.2 1.1e-43 149.0 5.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU85495.1 - 9.1e-69 231.6 20.0 4.2e-34 118.1 5.1 3.1 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU85495.1 - 2.1e-29 102.7 10.2 2.3e-15 57.0 1.2 2.2 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.18 EAU85495.1 - 3.5e-05 23.8 10.3 0.0094 15.9 1.3 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EAU85495.1 - 3.7e-05 23.1 2.6 0.0031 16.9 0.8 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding PF02629.19 EAU85495.1 - 0.00092 19.8 1.9 0.96 10.2 0.1 3.1 2 0 0 2 2 2 2 CoA binding domain Shikimate_DH PF01488.20 EAU85495.1 - 0.2 11.7 1.5 8.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.23 EAU85495.1 - 0.4 10.8 7.1 2.1 8.5 0.8 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF543 PF04418.12 EAU85495.1 - 0.49 10.4 7.4 3.3 7.7 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF543) PglL_A PF15864.5 EAU85495.1 - 0.79 9.5 8.2 6.5 6.6 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase ADH_zinc_N PF00107.26 EAU85495.1 - 1.1 9.2 6.1 11 6.0 0.5 3.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase PDZ PF00595.24 EAU85495.1 - 2.6 8.4 5.0 4.3 7.8 0.2 2.5 2 0 0 2 2 2 0 PDZ domain Cyclin_N PF00134.23 EAU85496.2 - 1.8e-42 144.1 0.4 3.1e-42 143.3 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAU85496.2 - 9.7e-26 90.2 0.0 2.2e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain G-gamma PF00631.22 EAU85496.2 - 0.034 14.2 0.1 0.074 13.1 0.1 1.5 1 0 0 1 1 1 0 GGL domain SapB_2 PF03489.17 EAU85496.2 - 0.2 11.8 0.4 0.74 10.0 0.1 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 2 G-patch PF01585.23 EAU85497.1 - 2.5e-14 52.9 2.8 5.4e-14 51.8 2.8 1.6 1 1 0 1 1 1 1 G-patch domain FHA PF00498.26 EAU85497.1 - 8.8e-10 38.8 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 EAU85497.1 - 6.7e-06 26.1 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Ribosomal_60s PF00428.19 EAU85498.1 - 0.16 12.6 0.3 0.16 12.6 0.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TOM13 PF08219.11 EAU85500.1 - 3.5e-13 49.3 0.1 9.1e-13 48.0 0.1 1.7 1 0 0 1 1 1 1 Outer membrane protein TOM13 Acyl-CoA_dh_1 PF00441.24 EAU85501.1 - 1.1e-28 100.4 0.3 1.7e-28 99.7 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EAU85501.1 - 5.2e-19 68.2 0.0 1.3e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EAU85501.1 - 1.1e-17 64.0 0.4 2.4e-17 62.9 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EAU85501.1 - 3.4e-17 63.1 0.0 8.3e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EAU85501.1 - 0.0011 19.3 0.1 0.0018 18.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.24 EAU85502.1 - 8.3e-31 107.2 1.2 1.3e-30 106.6 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EAU85502.1 - 3.7e-17 62.2 0.0 9.8e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EAU85502.1 - 2e-16 60.0 0.3 3.9e-16 59.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EAU85502.1 - 3.5e-11 43.7 0.0 1.1e-10 42.2 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EAU85502.1 - 2.5e-07 31.0 0.8 5.2e-07 30.0 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EAU85502.1 - 0.019 14.7 0.0 3.6 7.2 0.0 2.3 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF4218 PF13960.6 EAU85504.2 - 7.2e-06 25.6 0.0 1.9e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) RyR PF02026.16 EAU85505.1 - 4.1 7.7 5.5 12 6.1 0.3 3.3 1 1 2 3 3 3 0 RyR domain CoA_transf_3 PF02515.17 EAU85506.2 - 1.1e-48 166.2 0.0 1.1e-23 84.0 0.0 2.7 1 1 1 2 2 2 2 CoA-transferase family III Acyl-CoA_dh_1 PF00441.24 EAU85507.1 - 5.3e-30 104.6 0.3 7.8e-30 104.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAU85507.1 - 1.5e-20 73.2 0.5 2.9e-20 72.3 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EAU85507.1 - 1e-17 64.0 0.0 2.5e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EAU85507.1 - 1e-16 61.6 0.0 2.5e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EAU85507.1 - 0.00013 22.2 0.1 0.00025 21.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 EAU85508.2 - 1.6e-12 47.0 0.4 4.1e-12 45.7 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU85508.2 - 0.0005 20.1 10.3 0.00082 19.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_3 PF01757.22 EAU85508.2 - 0.085 11.9 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Acyltransferase family Apolipoprotein PF01442.18 EAU85509.1 - 1e-05 25.5 16.6 1e-05 25.5 16.6 2.1 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EAU85509.1 - 0.011 16.2 23.6 0.059 13.9 2.5 4.3 1 1 1 2 2 2 0 YtxH-like protein NDUFA12 PF05071.16 EAU85509.1 - 0.12 13.3 0.7 0.22 12.4 0.1 1.8 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF883 PF05957.13 EAU85509.1 - 1 10.0 39.7 0.11 13.2 3.7 4.5 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) V-ATPase_G_2 PF16999.5 EAU85509.1 - 1.2 9.6 22.0 0.86 10.1 2.8 3.4 3 0 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit KfrA_N PF11740.8 EAU85509.1 - 6.4 7.5 18.3 0.22 12.2 4.0 3.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term ANTAR PF03861.14 EAU85511.1 - 0.12 12.3 0.9 0.23 11.3 0.9 1.4 1 0 0 1 1 1 0 ANTAR domain PsbJ PF01788.17 EAU85511.1 - 1.2 9.0 3.8 2.7 7.9 3.8 1.6 1 1 0 1 1 1 0 PsbJ UPF0154 PF03672.13 EAU85511.1 - 4.1 7.5 5.2 0.92 9.6 0.1 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0154) SH3_9 PF14604.6 EAU85512.1 - 0.0009 19.1 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain TMEM52 PF14979.6 EAU85512.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 DUF4059 PF13268.6 EAU85512.1 - 0.16 12.4 0.1 0.28 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) DUF2370 PF10176.9 EAU85513.2 - 3e-71 239.7 1.5 3.4e-71 239.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) WD40 PF00400.32 EAU85514.2 - 6.7e-07 29.9 3.1 0.36 11.8 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EAU85514.2 - 0.0086 14.9 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EAU85514.2 - 0.013 15.8 0.0 0.078 13.3 0.0 2.1 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SPC22 PF04573.12 EAU85515.2 - 5.3e-53 179.0 0.7 6.3e-53 178.8 0.7 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Pkinase PF00069.25 EAU85516.2 - 3.3e-48 164.3 0.0 9.7e-48 162.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85516.2 - 1.2e-18 67.4 0.0 6e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase LysM PF01476.20 EAU85518.1 - 0.14 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 LysM domain ABC_membrane PF00664.23 EAU85519.2 - 1.4e-57 195.4 25.3 1.9e-30 106.4 7.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAU85519.2 - 1.1e-51 175.0 0.0 3.3e-29 102.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAU85519.2 - 4.8e-08 32.7 3.7 0.0088 15.5 0.0 3.9 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAU85519.2 - 2.2e-05 24.9 0.0 0.036 14.5 0.0 3.2 2 1 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 EAU85519.2 - 3.1e-05 24.0 1.3 0.062 13.4 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EAU85519.2 - 5.1e-05 23.2 4.1 0.1 12.4 0.1 3.3 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAU85519.2 - 6.9e-05 22.5 0.9 0.2 11.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EAU85519.2 - 0.00046 20.8 5.3 0.38 11.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain Roc PF08477.13 EAU85519.2 - 0.00055 20.1 0.4 0.22 11.7 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EAU85519.2 - 0.00056 19.5 0.1 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EAU85519.2 - 0.00062 19.7 0.4 0.73 9.7 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EAU85519.2 - 0.0013 18.5 0.0 0.2 11.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 EAU85519.2 - 0.002 18.0 3.1 6.2 6.5 0.2 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EAU85519.2 - 0.0022 17.8 1.7 1 9.1 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EAU85519.2 - 0.0029 17.2 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAU85519.2 - 0.0062 15.8 1.3 0.74 9.1 0.2 2.7 3 0 0 3 3 3 1 Zeta toxin TsaE PF02367.17 EAU85519.2 - 0.0087 16.1 0.3 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EAU85519.2 - 0.0099 15.5 2.3 0.11 12.0 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EAU85519.2 - 0.01 15.8 0.4 0.062 13.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EAU85519.2 - 0.01 16.1 1.3 1.1 9.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 EAU85519.2 - 0.016 14.2 3.0 1.5 7.6 0.3 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 EAU85519.2 - 0.019 15.5 0.1 12 6.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EAU85519.2 - 0.033 14.3 2.7 3.1 7.8 0.2 2.6 2 0 0 2 2 2 0 Dynamin family ATP-synt_ab PF00006.25 EAU85519.2 - 0.051 13.2 0.0 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EAU85519.2 - 0.051 12.7 0.3 6.6 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EAU85519.2 - 0.059 13.3 0.1 2.1 8.2 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea MobB PF03205.14 EAU85519.2 - 0.077 12.9 1.1 0.47 10.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_11 PF13086.6 EAU85519.2 - 0.097 12.4 0.1 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RecA PF00154.21 EAU85519.2 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein RNA_helicase PF00910.22 EAU85519.2 - 0.18 12.2 0.1 34 4.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EAU85519.2 - 0.23 11.6 2.3 5.5 7.2 0.3 3.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EAU85519.2 - 0.67 9.7 2.2 31 4.2 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Actin PF00022.19 EAU85522.1 - 3.2e-88 296.1 0.0 9.8e-87 291.2 0.0 2.0 1 1 0 1 1 1 1 Actin UPF0061 PF02696.14 EAU85523.1 - 1.9e-102 343.5 0.0 2.8e-102 342.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family 7TMR-HDED PF07697.11 EAU85523.1 - 0.025 14.7 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 7TM-HD extracellular Pkinase PF00069.25 EAU85524.2 - 5.9e-41 140.6 0.0 8.9e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85524.2 - 6.7e-41 140.3 0.0 1e-40 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAU85524.2 - 0.0071 15.7 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU85524.2 - 0.021 14.8 1.9 0.05 13.5 0.1 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU85524.2 - 0.074 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EAU85524.2 - 0.1 12.2 0.3 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Hva1_TUDOR PF11160.8 EAU85525.2 - 1.4e-19 70.0 0.2 1.6e-19 69.8 0.2 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain HMG_box PF00505.19 EAU85526.1 - 3.4e-11 43.4 0.7 7e-11 42.4 0.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU85526.1 - 0.0034 17.9 0.1 0.0071 16.9 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain ECH_1 PF00378.20 EAU85527.1 - 2e-22 79.7 0.0 3.3e-22 79.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAU85527.1 - 4.6e-08 32.9 0.0 6.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase B12-binding_2 PF02607.17 EAU85527.1 - 0.099 13.1 0.2 5 7.6 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain T4_Rnl2_C PF18043.1 EAU85527.1 - 0.17 12.1 0.1 0.43 10.8 0.0 1.7 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal ThuA PF06283.11 EAU85529.2 - 2.2e-62 211.0 0.0 2.6e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation DnaJ_C PF01556.18 EAU85530.2 - 6.1e-38 130.2 0.2 8.5e-38 129.7 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EAU85530.2 - 1.9e-09 37.7 21.6 3.2e-09 37.0 21.6 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 EAU85530.2 - 2e-07 31.0 0.2 4.1e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.19 EAU85530.2 - 4.9 7.2 15.1 12 5.9 0.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EAU85530.2 - 8.5 6.4 19.7 1.9 8.5 5.7 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Methyltr_RsmB-F PF01189.17 EAU85531.2 - 4.3e-18 65.7 0.0 5.9e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 EAU85531.2 - 0.00057 19.1 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin SF1-HH PF16275.5 EAU85532.1 - 4e-40 136.7 1.7 8.5e-40 135.6 1.7 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EAU85532.1 - 1.1e-11 44.3 8.9 1.4e-05 24.9 0.3 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EAU85532.1 - 1.1e-06 28.4 3.7 0.0024 17.8 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EAU85532.1 - 1.9e-06 27.6 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 KH domain CCDC-167 PF15188.6 EAU85532.1 - 0.0009 19.5 1.2 1 9.8 0.1 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 zf-CCHC_6 PF15288.6 EAU85532.1 - 0.0032 17.3 8.6 0.54 10.1 0.9 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EAU85532.1 - 0.0059 16.3 7.1 0.41 10.4 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 EAU85532.1 - 0.17 12.3 4.5 0.38 11.1 4.5 1.6 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.6 EAU85532.1 - 3.6 7.5 9.8 0.36 10.7 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle ERCC3_RAD25_C PF16203.5 EAU85533.1 - 1.3e-123 411.1 0.0 2.7e-123 410.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EAU85533.1 - 4.6e-29 101.1 0.0 1.3e-28 99.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU85533.1 - 2.8e-16 60.0 0.0 5.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAU85533.1 - 2.2e-10 40.9 0.0 6.2e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAU85533.1 - 5.4e-10 38.5 0.0 7.1e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EAU85533.1 - 1.7e-05 24.7 0.1 2.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EAU85533.1 - 0.12 11.3 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 bZIP_1 PF00170.21 EAU85534.1 - 0.0002 21.4 2.5 0.00036 20.6 2.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAU85534.1 - 0.013 15.5 2.5 0.025 14.6 2.5 1.4 1 0 0 1 1 1 0 Basic region leucine zipper CCDC106 PF15794.5 EAU85534.1 - 0.068 12.9 0.7 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 TSC22 PF01166.18 EAU85534.1 - 0.087 13.1 0.3 0.18 12.1 0.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family HMGL-like PF00682.19 EAU85537.1 - 1.6e-80 270.5 0.3 2.3e-80 270.0 0.3 1.2 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 EAU85537.1 - 0.15 12.6 0.2 0.3 11.6 0.2 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Cys_Met_Meta_PP PF01053.20 EAU85539.1 - 1.4e-126 422.1 0.0 1.8e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 EAU85539.1 - 1.2e-15 57.4 0.5 4.8e-15 55.5 0.5 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EAU85539.1 - 3e-08 33.9 0.0 1.1e-07 32.1 0.0 2.0 1 1 1 2 2 2 1 GHMP kinases C terminal Aminotran_1_2 PF00155.21 EAU85539.1 - 0.00019 20.7 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EAU85539.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EAU85539.1 - 0.0028 16.3 0.0 0.0082 14.7 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase GalKase_gal_bdg PF10509.9 EAU85539.1 - 0.0033 17.0 0.0 0.0073 15.8 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature SelA PF03841.13 EAU85539.1 - 0.019 13.9 0.0 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.21 EAU85539.1 - 0.043 13.1 0.0 0.12 11.6 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Terpene_synth_C PF03936.16 EAU85540.1 - 5.3e-06 26.0 0.0 7.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.19 EAU85541.2 - 6.6e-33 112.4 0.4 4.9e-32 109.6 0.1 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EAU85541.2 - 8.4e-31 106.4 0.0 1.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EAU85541.2 - 0.00059 19.8 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease Trigger_C PF05698.14 EAU85541.2 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus WD40 PF00400.32 EAU85542.2 - 3.5e-16 59.3 4.3 0.00021 22.0 0.0 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU85542.2 - 1.1e-06 28.9 0.0 0.41 11.0 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 EAU85544.2 - 1.2e-57 194.0 0.1 1.4e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU85544.2 - 9.3e-20 71.0 0.0 1.9e-19 70.0 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU85544.2 - 5.5e-08 32.5 0.0 7.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAU85544.2 - 6.1e-05 23.0 0.0 0.094 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAU85544.2 - 6.6e-05 22.5 0.0 0.00016 21.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAU85544.2 - 0.0048 17.0 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU85544.2 - 0.0067 16.0 0.1 0.017 14.7 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Ser_hydrolase PF06821.13 EAU85544.2 - 0.18 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.17 EAU85544.2 - 0.19 11.5 1.7 1.5 8.6 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Mito_carr PF00153.27 EAU85546.2 - 8.4e-55 182.7 1.3 1.3e-23 82.8 1.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_16 PF10294.9 EAU85547.2 - 2e-22 79.8 0.0 3.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 EAU85548.2 - 4e-72 242.7 0.6 7.9e-72 241.7 0.2 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAU85548.2 - 2.5e-41 140.2 0.3 1.3e-40 137.9 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EAU85548.2 - 0.00017 21.2 0.4 0.00076 19.1 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EAU85548.2 - 0.00031 20.5 0.5 0.15 11.9 0.0 3.1 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glyco_hydro_79C PF16862.5 EAU85549.2 - 4e-14 53.4 0.0 7.9e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Rad51 PF08423.11 EAU85550.2 - 1.8e-12 47.0 0.0 2.5e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EAU85550.2 - 0.00011 21.8 0.0 0.00024 20.6 0.0 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EAU85550.2 - 0.011 15.1 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.15 EAU85550.2 - 0.018 14.4 0.0 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 EAU85550.2 - 0.044 13.8 0.0 0.089 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU85550.2 - 0.08 12.5 0.0 0.84 9.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU85550.2 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EAU85550.2 - 0.12 12.1 0.0 5.7 6.7 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase TauD PF02668.16 EAU85551.1 - 1.2e-59 202.3 0.1 1.5e-59 202.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATA PF00320.27 EAU85552.2 - 3.4e-15 55.4 4.2 6.3e-15 54.5 4.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Adaptin_N PF01602.20 EAU85554.2 - 5.8e-74 249.5 0.0 2e-73 247.8 0.0 1.7 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAU85554.2 - 1.1e-11 45.0 0.0 2e-08 34.5 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAU85554.2 - 0.00012 22.0 0.7 3 8.3 0.0 6.0 7 0 0 7 7 6 1 HEAT repeat HEAT_2 PF13646.6 EAU85554.2 - 0.00087 19.6 0.0 0.083 13.3 0.0 3.2 3 0 0 3 3 2 1 HEAT repeats Mpp10 PF04006.12 EAU85554.2 - 0.0026 16.3 16.3 0.0047 15.5 16.3 1.4 1 0 0 1 1 1 1 Mpp10 protein DUF2322 PF10084.9 EAU85554.2 - 0.13 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) SAPS PF04499.15 EAU85554.2 - 0.34 9.6 3.7 0.63 8.7 3.7 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAF PF15715.5 EAU85554.2 - 1 9.9 12.5 2.7 8.6 12.5 1.7 1 0 0 1 1 1 0 PCNA-associated factor histone like domain PPP4R2 PF09184.11 EAU85554.2 - 1.9 8.0 21.9 4.4 6.8 21.9 1.6 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 EAU85554.2 - 5.3 6.8 15.4 16 5.2 15.4 1.8 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EAU85554.2 - 6.5 7.2 10.9 1.2e+02 3.1 11.5 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF913 PF06025.12 EAU85554.2 - 8.2 5.3 9.5 2e+02 0.7 11.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) ATG16 PF08614.11 EAU85555.1 - 0.002 18.4 3.1 0.002 18.4 3.1 2.9 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) SlyX PF04102.12 EAU85555.1 - 9 7.0 11.1 3 8.5 2.0 2.7 2 0 0 2 2 2 0 SlyX WD40 PF00400.32 EAU85556.1 - 0.18 12.8 2.2 3.2e+02 2.4 0.0 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat FH2 PF02181.23 EAU85556.1 - 0.49 9.5 2.7 0.78 8.8 2.7 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Serinc PF03348.15 EAU85557.1 - 1.3e-146 488.9 9.2 1.5e-146 488.7 9.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) RRM_1 PF00076.22 EAU85560.1 - 2.2e-15 56.2 0.0 4.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRN3 PF05327.11 EAU85560.1 - 0.057 11.9 2.8 0.13 10.8 2.8 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MBOAT_2 PF13813.6 EAU85562.1 - 3.4e-17 62.5 3.0 1.3e-16 60.6 3.0 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_25 PF13649.6 EAU85563.2 - 0.0025 18.5 0.0 0.092 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Maf1 PF09174.10 EAU85564.1 - 7e-42 143.5 0.2 3.7e-35 121.6 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator Pectate_lyase PF03211.13 EAU85565.2 - 3.8e-70 235.6 0.1 4.8e-70 235.3 0.1 1.0 1 0 0 1 1 1 1 Pectate lyase Pectate_lyase PF03211.13 EAU85566.1 - 6.2e-82 274.1 4.6 7.5e-82 273.8 4.6 1.1 1 0 0 1 1 1 1 Pectate lyase TPR_2 PF07719.17 EAU85567.2 - 5.4e-27 91.7 14.8 2.8e-06 27.0 0.0 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU85567.2 - 3.6e-24 84.8 12.0 1.7e-11 44.1 0.1 6.2 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EAU85567.2 - 2.4e-21 74.6 8.2 2.6e-07 30.2 0.0 6.7 8 0 0 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAU85567.2 - 1.8e-17 63.6 4.7 0.00027 21.4 0.2 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU85567.2 - 7.6e-16 56.9 8.5 0.00038 20.4 0.0 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EAU85567.2 - 1.5e-13 51.2 9.2 1.3e-06 28.9 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU85567.2 - 4.9e-13 48.5 5.2 1.1e-05 25.0 0.0 6.2 6 1 1 7 7 7 2 TPR repeat TPR_12 PF13424.6 EAU85567.2 - 5.2e-13 49.1 17.0 2.6e-08 34.0 0.2 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU85567.2 - 1.2e-11 43.8 6.5 0.00029 20.6 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EAU85567.2 - 5.9e-10 38.7 6.1 0.0019 18.0 0.0 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAU85567.2 - 2.2e-08 33.9 11.4 0.0027 18.0 0.0 7.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAU85567.2 - 6.4e-07 29.6 18.2 0.48 11.2 0.1 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU85567.2 - 2.7e-06 27.7 18.2 0.12 13.3 0.0 8.0 5 2 4 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAU85567.2 - 2.3e-05 24.5 8.6 0.36 11.0 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAU85567.2 - 0.00017 21.5 3.2 0.01 15.9 0.1 4.3 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EAU85567.2 - 0.0012 18.9 0.3 12 6.4 0.0 3.9 3 0 0 3 3 3 0 PPR repeat DUF2225 PF09986.9 EAU85567.2 - 0.015 15.0 0.2 0.59 9.8 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 EAU85567.2 - 0.018 15.6 1.4 24 5.9 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF-1a PF01176.19 EAU85568.2 - 4e-22 77.8 0.0 5.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ank_2 PF12796.7 EAU85569.2 - 9.9e-09 35.7 0.0 2.6e-06 27.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU85569.2 - 0.00017 21.7 0.1 1.3 9.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAU85569.2 - 0.00093 19.5 0.2 2.4 8.6 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU85569.2 - 0.0056 17.2 0.1 0.054 14.1 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 EAU85569.2 - 0.12 12.4 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) YhhN PF07947.14 EAU85571.1 - 4.8e-27 94.8 12.1 1.1e-23 83.8 5.5 2.7 2 1 1 3 3 3 2 YhhN family DHDPS PF00701.22 EAU85572.2 - 1.5e-38 132.1 0.0 2.2e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Dynamin_N PF00350.23 EAU85573.1 - 9.6e-43 146.1 0.0 2.1e-42 145.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EAU85573.1 - 5.6e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EAU85573.1 - 5.8e-05 23.1 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase MetOD2 PF18548.1 EAU85573.1 - 0.97 9.6 3.5 5.9 7.1 0.0 3.3 4 0 0 4 4 4 0 Metanogen output domain 2 RecG_N PF17190.4 EAU85573.1 - 1.5 9.6 5.0 3.5 8.4 0.2 3.1 3 0 0 3 3 3 0 RecG N-terminal helical domain SCP2 PF02036.17 EAU85574.2 - 1.7e-24 86.2 1.4 2.1e-24 85.9 1.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EAU85574.2 - 8.3e-06 26.1 1.2 1e-05 25.8 1.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EAU85574.2 - 0.0025 18.2 0.2 0.0055 17.1 0.2 1.6 1 1 0 1 1 1 1 Sterol carrier protein domain Big_6 PF17936.1 EAU85574.2 - 0.081 13.2 0.3 0.36 11.1 0.1 2.1 1 1 1 2 2 2 0 Bacterial Ig domain AAA_12 PF13087.6 EAU85577.1 - 7e-34 117.2 0.1 1.8e-33 115.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU85577.1 - 2.4e-26 93.1 0.2 4.1e-12 46.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EAU85577.1 - 1.4e-15 57.5 0.0 4.4e-15 55.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU85577.1 - 6.3e-13 49.3 0.0 2.3e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EAU85577.1 - 9.2e-07 28.8 0.3 0.022 14.5 0.0 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EAU85577.1 - 5.3e-06 26.9 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EAU85577.1 - 1.1e-05 24.9 0.0 0.0023 17.2 0.0 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EAU85577.1 - 8.4e-05 22.9 0.1 0.001 19.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EAU85577.1 - 0.00012 22.0 0.0 0.00044 20.1 0.0 2.0 2 1 0 2 2 2 1 Helicase ResIII PF04851.15 EAU85577.1 - 0.00014 22.0 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAU85577.1 - 0.00093 19.0 0.0 0.0026 17.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 EAU85577.1 - 0.0034 17.8 0.0 0.0085 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EAU85577.1 - 0.0064 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EAU85577.1 - 0.025 14.0 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EAU85577.1 - 0.027 13.6 0.0 0.067 12.4 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 EAU85577.1 - 0.034 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU85577.1 - 0.037 13.5 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EAU85577.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EAU85577.1 - 0.06 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase PF06745.13 EAU85577.1 - 0.084 12.2 0.4 0.38 10.1 0.0 2.2 2 1 0 2 2 2 0 KaiC AAA_23 PF13476.6 EAU85577.1 - 0.093 13.2 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EAU85577.1 - 0.16 11.5 0.0 0.56 9.7 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_12 PF13087.6 EAU85578.2 - 1.7e-35 122.5 0.4 2.9e-35 121.7 0.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU85578.2 - 3e-17 63.3 0.0 4.6e-11 43.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EAU85578.2 - 3.2e-16 59.6 0.0 1.2e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU85578.2 - 2.9e-13 50.4 0.0 1.6e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EAU85578.2 - 2.8e-05 24.0 0.1 0.0075 16.0 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EAU85578.2 - 0.0006 19.2 0.7 0.18 11.0 0.2 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EAU85578.2 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.8 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 EAU85578.2 - 0.0016 18.0 0.1 0.038 13.4 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 EAU85578.2 - 0.0018 18.7 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU85578.2 - 0.02 15.2 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAU85578.2 - 0.023 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 EAU85578.2 - 0.032 14.0 0.1 0.08 12.7 0.1 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Shugoshin_C PF07557.11 EAU85578.2 - 0.13 12.1 0.9 0.23 11.3 0.9 1.4 1 0 0 1 1 1 0 Shugoshin C terminus UvrD-helicase PF00580.21 EAU85578.2 - 0.16 11.5 0.0 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Carn_acyltransf PF00755.20 EAU85579.2 - 4.1e-159 530.9 0.0 4.7e-159 530.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase XPG_I PF00867.18 EAU85580.2 - 1.2e-28 99.2 0.0 5.4e-28 97.2 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EAU85580.2 - 4.5e-22 78.4 0.0 1.2e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EAU85580.2 - 0.0028 17.2 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing CtaG_Cox11 PF04442.14 EAU85581.2 - 1.3e-60 203.9 0.1 1.7e-60 203.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.31 EAU85582.1 - 5.8e-15 55.2 0.7 1.8e-14 53.6 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain DUF2017 PF09438.10 EAU85582.1 - 0.013 15.4 3.0 0.022 14.6 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) PfkB PF00294.24 EAU85584.1 - 4.2e-14 52.5 0.0 2.3e-08 33.7 0.0 3.1 3 0 0 3 3 3 3 pfkB family carbohydrate kinase SH3_1 PF00018.28 EAU85585.1 - 2.7e-13 49.3 0.4 4.2e-13 48.7 0.4 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU85585.1 - 1.4e-11 44.0 0.1 2.4e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU85585.1 - 4.8e-11 42.2 0.0 7.9e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 EAU85585.1 - 1.4 8.9 9.9 2.7 8.0 9.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mce4_CUP1 PF11887.8 EAU85585.1 - 1.9 7.9 4.8 2.6 7.4 4.8 1.3 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Nup88 PF10168.9 EAU85586.2 - 0.34 8.7 9.8 0.53 8.0 9.8 1.2 1 0 0 1 1 1 0 Nuclear pore component Fib_alpha PF08702.10 EAU85586.2 - 0.58 10.3 4.7 1.4 9.1 4.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 EAU85586.2 - 3.3 8.0 13.0 11 6.2 0.6 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein UPF0242 PF06785.11 EAU85586.2 - 7.2 6.7 11.3 4.7 7.3 1.4 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 EAU85586.2 - 9.1 4.8 10.5 3.7 6.0 6.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Phage_holin_2_4 PF16082.5 EAU85587.2 - 0.068 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Chordopox_A13L PF05961.11 EAU85587.2 - 0.24 11.6 0.0 0.59 10.4 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SKG6 PF08693.10 EAU85587.2 - 0.55 9.7 3.1 1.3 8.5 3.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Voldacs PF03517.13 EAU85588.1 - 2.3e-28 99.0 0.2 2.3e-28 99.0 0.2 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling PI3Ka PF00613.20 EAU85589.2 - 3.5e-55 186.3 0.1 5.5e-55 185.6 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EAU85589.2 - 1.4e-47 162.6 0.0 5e-44 151.0 0.0 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EAU85589.2 - 2.1e-40 137.9 0.0 3.4e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 EAU85589.2 - 0.06 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Aminotran_3 PF00202.21 EAU85590.2 - 1.6e-44 152.2 0.0 2.1e-42 145.3 0.0 2.5 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.6 EAU85590.2 - 2.5e-17 63.4 0.0 4.5e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EAU85590.2 - 0.17 12.0 0.0 0.39 10.8 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain APOBEC4 PF18775.1 EAU85591.2 - 0.0058 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 APOBEC4 IlvN PF07991.12 EAU85592.1 - 3e-46 157.0 0.0 1.5e-45 154.7 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EAU85592.1 - 3.5e-38 131.1 0.0 5.1e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TauD PF02668.16 EAU85593.1 - 2e-38 132.8 0.0 3e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EAU85593.1 - 7.4e-19 68.2 1.4 9e-19 67.9 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 EAU85593.1 - 0.0041 16.3 0.0 0.018 14.2 0.0 1.8 2 0 0 2 2 2 1 CsiD DUF2973 PF11189.8 EAU85596.2 - 0.083 13.0 0.3 0.49 10.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Sde2_N_Ubi PF13019.6 EAU85597.1 - 5.8e-55 185.6 0.1 5.8e-55 185.6 0.1 1.7 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain GGACT PF06094.12 EAU85598.2 - 5e-12 46.5 0.0 7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Na_Ca_ex PF01699.24 EAU85600.2 - 4.7e-31 107.8 31.1 5.5e-18 65.4 17.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PTS_EIIB PF00367.20 EAU85600.2 - 0.082 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 phosphotransferase system, EIIB F-box_4 PF15966.5 EAU85601.2 - 0.077 12.9 0.1 0.27 11.1 0.1 2.0 1 0 0 1 1 1 0 F-box RNA_pol_Rpc34 PF05158.12 EAU85605.2 - 2.7e-35 122.4 0.0 3.1e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 EAU85605.2 - 0.0086 16.4 0.8 0.018 15.4 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulator MarR_2 PF12802.7 EAU85605.2 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 MarR family HSP20 PF00011.21 EAU85606.2 - 5.2e-06 26.6 0.0 9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PI3K_1B_p101 PF10486.9 EAU85608.2 - 0.00067 17.6 0.5 0.00078 17.4 0.5 1.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit IR1-M PF12185.8 EAU85608.2 - 0.016 15.1 0.8 0.016 15.1 0.8 2.4 1 1 1 2 2 2 0 Nup358/RanBP2 E3 ligase domain tRNA-synt_1g PF09334.11 EAU85609.1 - 5.2e-131 437.0 1.0 3.5e-129 431.0 1.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 EAU85609.1 - 1.5e-07 31.4 4.0 3.9e-07 30.1 4.0 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 EAU85609.1 - 0.00016 20.1 0.0 0.00039 18.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAU85609.1 - 0.0039 17.2 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA MCPVI PF02993.14 EAU85609.1 - 0.4 10.5 1.3 0.91 9.3 0.1 2.0 2 0 0 2 2 2 0 Minor capsid protein VI Cellulase PF00150.18 EAU85611.2 - 3.6e-39 134.9 0.1 5.6e-32 111.3 0.7 2.1 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EAU85611.2 - 5.3e-11 42.3 12.0 5.3e-11 42.3 12.0 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain MFS_1 PF07690.16 EAU85612.2 - 1.2e-10 40.9 25.5 5.9e-08 32.0 19.1 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EAU85612.2 - 0.014 13.7 0.0 0.014 13.7 0.0 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EAU85612.2 - 0.024 13.5 2.0 0.18 10.6 0.0 2.6 3 0 0 3 3 3 0 MFS_1 like family DUF4834 PF16118.5 EAU85612.2 - 0.12 13.4 0.0 43 5.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) F-box-like PF12937.7 EAU85613.2 - 7.4e-08 32.2 0.3 7.4e-08 32.2 0.3 2.5 3 0 0 3 3 3 1 F-box-like Rubrerythrin PF02915.17 EAU85615.2 - 0.0058 17.0 4.4 0.0058 17.0 4.4 1.7 2 0 0 2 2 2 1 Rubrerythrin BAR_3 PF16746.5 EAU85615.2 - 0.038 13.7 6.9 0.058 13.1 6.9 1.2 1 0 0 1 1 1 0 BAR domain of APPL family HIP1_clath_bdg PF16515.5 EAU85615.2 - 0.51 11.0 9.5 0.03 14.9 3.6 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Pheromone PF08015.11 EAU85615.2 - 0.72 10.9 0.0 0.72 10.9 0.0 4.7 4 0 0 4 4 4 0 Fungal mating-type pheromone OmpH PF03938.14 EAU85615.2 - 3 8.2 9.2 2.6 8.4 1.7 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) adh_short_C2 PF13561.6 EAU85616.1 - 1.1e-51 175.7 2.6 1.5e-51 175.2 2.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU85616.1 - 1.7e-48 164.7 5.0 2.1e-48 164.4 5.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU85616.1 - 4.1e-05 23.6 4.4 0.00044 20.2 4.4 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU85616.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GGGtGRT PF14057.6 EAU85616.1 - 0.012 14.6 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 0 GGGtGRT protein Eno-Rase_NADH_b PF12242.8 EAU85616.1 - 0.055 13.2 0.4 0.12 12.1 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_23 PF13489.6 EAU85617.1 - 0.0038 17.1 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU85617.1 - 0.11 12.3 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain ATP_synt_H PF05493.13 EAU85618.1 - 1.1e-19 70.6 4.1 1.3e-19 70.4 4.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H FliP PF00813.20 EAU85618.1 - 0.012 15.5 1.2 0.014 15.3 1.2 1.0 1 0 0 1 1 1 0 FliP family ARL6IP6 PF15062.6 EAU85618.1 - 0.059 13.5 1.2 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix YrhC PF14143.6 EAU85618.1 - 0.83 9.8 4.3 3.8 7.7 0.5 2.1 1 1 1 2 2 2 0 YrhC-like protein p450 PF00067.22 EAU85619.1 - 2.8e-72 244.0 0.4 2.9e-71 240.6 0.4 2.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1116 PF06545.11 EAU85619.1 - 0.096 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) MAP65_ASE1 PF03999.12 EAU85620.2 - 0.2 10.3 14.7 0.32 9.7 14.7 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GREB1 PF15782.5 EAU85620.2 - 1.9 5.5 7.1 2.4 5.1 7.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pol_alpha_B_N PF08418.10 EAU85620.2 - 6 6.8 8.9 9.5 6.1 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal p450 PF00067.22 EAU85621.2 - 5.1e-56 190.3 0.0 7.6e-55 186.5 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 PsbT PF01405.17 EAU85621.2 - 1 9.2 4.9 2.9 7.8 0.5 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre T protein Alpha_kinase PF02816.18 EAU85624.1 - 2e-05 24.8 0.0 2.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Citrate_synt PF00285.21 EAU85625.2 - 2e-26 92.9 0.0 2.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Peptidase_M24 PF00557.24 EAU85629.2 - 1.5e-11 44.4 0.3 2.6e-11 43.6 0.3 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_25 PF13649.6 EAU85630.2 - 9.9e-12 45.4 0.0 2.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU85630.2 - 2.6e-07 31.2 0.0 5.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU85630.2 - 1.6e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU85630.2 - 2.5e-05 24.2 0.0 5.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU85630.2 - 0.00031 20.2 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EAU85630.2 - 0.0043 17.8 0.0 0.031 15.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EAU85630.2 - 0.0082 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EAU85630.2 - 0.034 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 EAU85630.2 - 0.054 13.6 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EAU85630.2 - 0.21 11.0 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 EAU85630.2 - 0.23 10.8 0.0 0.69 9.2 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NDUF_B8 PF05821.11 EAU85631.2 - 0.0062 16.4 0.2 0.013 15.3 0.2 1.6 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pex14_N PF04695.13 EAU85631.2 - 0.036 14.7 0.1 0.072 13.8 0.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ODV-E18 PF10717.9 EAU85632.2 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 PsbJ PF01788.17 EAU85632.2 - 0.14 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 PsbJ PH PF00169.29 EAU85633.2 - 0.0041 17.6 0.0 0.016 15.7 0.0 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 EAU85633.2 - 0.0088 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain K_channel_TID PF07941.11 EAU85633.2 - 0.31 11.5 8.1 1.5 9.3 2.3 3.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DNA_pol_phi PF04931.13 EAU85633.2 - 1.7 6.7 3.4 3.3 5.7 3.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi DnaJ PF00226.31 EAU85634.2 - 1.8e-16 60.0 0.0 3.5e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.19 EAU85635.2 - 2.2e-38 131.6 0.0 2.9e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EAU85635.2 - 0.0086 16.0 0.0 0.034 14.0 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EAU85635.2 - 0.054 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF1574 PF07611.11 EAU85635.2 - 0.1 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) RsgA_GTPase PF03193.16 EAU85635.2 - 0.1 12.5 0.1 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Frag1 PF10277.9 EAU85636.2 - 2.5e-10 40.3 0.2 2.5e-10 40.3 0.2 2.7 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family RRF PF01765.19 EAU85637.2 - 1.1e-28 100.2 0.1 1.1e-28 100.2 0.1 1.8 1 1 1 2 2 2 1 Ribosome recycling factor CDC14 PF08045.11 EAU85637.2 - 0.06 12.4 0.2 0.06 12.4 0.2 1.7 2 0 0 2 2 2 0 Cell division control protein 14, SIN component Sas10 PF09368.10 EAU85637.2 - 0.084 13.4 5.9 0.25 11.9 0.4 2.7 2 1 1 3 3 3 0 Sas10 C-terminal domain DUF4168 PF13767.6 EAU85637.2 - 1.4 10.1 6.1 9.8 7.4 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) Peptidase_C14 PF00656.22 EAU85638.2 - 2.6e-12 47.3 0.0 5.3e-12 46.2 0.0 1.4 2 0 0 2 2 2 1 Caspase domain Raptor_N PF14538.6 EAU85638.2 - 0.046 13.7 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DDE_3 PF13358.6 EAU85642.2 - 0.00061 19.6 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease Sirohm_synth_M PF14824.6 EAU85642.2 - 0.32 10.5 2.2 0.31 10.5 0.2 2.0 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central RRM_1 PF00076.22 EAU85647.1 - 8.6e-11 41.5 1.3 1.3e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 EAU85649.2 - 9.3e-08 31.8 11.2 1.8e-07 31.0 11.2 1.5 1 0 0 1 1 1 1 PHD-finger WSD PF15613.6 EAU85649.2 - 0.0038 17.7 0.0 0.0038 17.7 0.0 4.3 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif 5_nucleotid PF05761.14 EAU85649.2 - 0.49 9.2 8.1 1 8.2 8.1 1.4 1 0 0 1 1 1 0 5' nucleotidase family ANAPC10 PF03256.16 EAU85650.2 - 1.6e-44 151.8 0.0 2e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EAU85650.2 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.5 1 1 0 1 1 1 1 F5/8 type C domain ThiF PF00899.21 EAU85651.2 - 3.4e-54 183.8 0.0 5.4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EAU85651.2 - 6.7e-12 45.9 0.0 1.7e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 EAU85651.2 - 0.018 15.1 0.0 0.078 13.0 0.0 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase UBX PF00789.20 EAU85652.1 - 2.3e-13 50.1 0.2 3.7e-13 49.5 0.2 1.3 1 0 0 1 1 1 1 UBX domain PITH PF06201.13 EAU85653.2 - 1.2e-39 136.0 0.0 1.5e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Med25_VWA PF11265.8 EAU85654.2 - 9.6e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A LUC7 PF03194.15 EAU85654.2 - 0.058 13.0 0.1 0.09 12.4 0.1 1.2 1 0 0 1 1 1 0 LUC7 N_terminus DUF2313 PF10076.9 EAU85654.2 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) YchF-GTPase_C PF06071.13 EAU85656.2 - 6.3e-36 122.4 0.0 2e-35 120.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EAU85656.2 - 1.5e-17 63.7 0.0 4.8e-17 62.1 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU85656.2 - 2.9e-05 23.6 0.0 5.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.6 EAU85656.2 - 0.084 12.5 0.1 0.58 9.8 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 MMtag PF10159.9 EAU85657.2 - 1.5e-30 105.3 3.0 1.5e-30 105.3 3.0 3.1 2 1 0 2 2 2 1 Multiple myeloma tumor-associated RR_TM4-6 PF06459.12 EAU85657.2 - 6.6 6.5 18.6 9 6.0 18.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 EAU85657.2 - 9.8 5.4 15.3 12 5.1 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.26 EAU85660.1 - 3e-10 40.0 9.9 0.00016 22.0 3.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU85660.1 - 1.4e-08 34.7 5.0 1.8e-06 28.1 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU85660.1 - 1.5e-06 28.6 10.6 0.0007 20.2 2.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU85660.1 - 0.00017 21.8 7.8 0.079 13.3 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU85660.1 - 0.0024 18.2 8.4 0.77 10.2 3.6 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EAU85660.1 - 0.003 17.3 1.6 0.91 9.3 0.0 2.6 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-LYAR PF08790.11 EAU85660.1 - 0.01 15.7 5.0 0.27 11.2 1.6 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 EAU85660.1 - 0.049 13.7 8.6 0.25 11.4 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EAU85660.1 - 0.052 13.5 1.1 0.052 13.5 1.1 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 EAU85660.1 - 0.055 13.8 2.2 0.14 12.5 2.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon Rad50_zn_hook PF04423.14 EAU85660.1 - 0.26 11.2 0.6 20 5.1 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 EAU85660.1 - 0.75 10.2 7.2 0.45 10.9 0.9 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 EAU85660.1 - 1.5 9.0 4.0 1.1 9.4 0.6 2.3 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 EAU85661.2 - 3.5e-10 39.7 9.6 0.00012 22.3 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EAU85661.2 - 2.1e-05 24.2 11.3 0.001 18.8 1.4 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EAU85661.2 - 7.1e-05 23.3 14.9 0.012 16.4 1.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU85661.2 - 0.00013 22.2 4.5 0.033 14.5 0.8 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EAU85661.2 - 0.0044 16.9 0.9 0.013 15.4 0.9 1.8 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 EAU85661.2 - 0.0081 16.5 6.4 0.023 15.1 0.5 3.4 4 0 0 4 4 3 1 Zinc-finger double domain zf-met PF12874.7 EAU85661.2 - 0.096 13.1 7.3 0.69 10.4 1.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ephrin_rec_like PF07699.13 EAU85661.2 - 0.16 11.8 2.1 8.1 6.3 0.2 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-LYAR PF08790.11 EAU85661.2 - 0.19 11.7 2.5 15 5.6 0.5 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 EAU85661.2 - 1.7 9.0 6.1 10 6.5 1.6 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EAU85661.2 - 7.3 6.7 9.3 21 5.3 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EAU85662.1 - 0.047 14.5 1.2 0.1 13.5 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger SpmSyn_N PF17950.1 EAU85662.1 - 0.052 13.7 0.0 8.5 6.6 0.0 2.5 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal Glyco_hydro_cc PF11790.8 EAU85663.1 - 1.7e-47 162.0 0.0 2.2e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ERG4_ERG24 PF01222.17 EAU85665.2 - 1.7e-137 458.8 4.5 1.9e-137 458.6 4.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EAU85665.2 - 0.00065 19.3 0.1 0.00065 19.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EAU85665.2 - 0.027 14.9 0.6 0.15 12.5 0.0 2.5 2 0 0 2 2 2 0 Phospholipid methyltransferase ICMT PF04140.14 EAU85665.2 - 0.028 14.8 0.0 0.12 12.9 0.0 2.0 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Acetate_kinase PF00871.17 EAU85667.2 - 7.8e-86 288.2 0.0 6.4e-85 285.2 0.0 2.0 1 1 0 1 1 1 1 Acetokinase family XFP_N PF09364.10 EAU85668.1 - 2.2e-153 510.4 0.0 2.8e-153 510.0 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EAU85668.1 - 2.2e-79 265.6 0.0 5e-79 264.5 0.0 1.6 2 0 0 2 2 2 1 XFP C-terminal domain XFP PF03894.15 EAU85668.1 - 2e-75 252.3 0.0 3.1e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EAU85668.1 - 0.0042 16.9 0.2 0.0095 15.7 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 EAU85668.1 - 0.074 12.9 0.6 0.22 11.4 0.3 1.9 2 0 0 2 2 2 0 Transketolase, C-terminal domain Nucleoporin_FG PF13634.6 EAU85669.1 - 1e-53 180.1 297.0 2.3e-13 50.8 40.9 4.9 1 1 5 6 6 6 6 Nucleoporin FG repeat region Dynein_C PF18199.1 EAU85669.1 - 0.016 14.4 0.0 0.049 12.8 0.0 1.7 2 0 0 2 2 2 0 Dynein heavy chain C-terminal domain Nucleoporin_FG2 PF15967.5 EAU85669.1 - 0.17 10.4 65.4 0.49 8.9 63.6 2.3 1 1 0 1 1 1 0 Nucleoporin FG repeated region DUF4924 PF16271.5 EAU85669.1 - 0.19 11.7 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) DUF1640 PF07798.11 EAU85669.1 - 0.29 11.2 2.0 0.43 10.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) USP8_interact PF08941.10 EAU85670.2 - 0.07 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 USP8 interacting DUF5491 PF17595.2 EAU85670.2 - 0.088 13.1 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5491) Mitofilin PF09731.9 EAU85671.1 - 2.4e-114 383.5 23.5 3.4e-114 383.0 23.5 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein PE PF00934.20 EAU85671.1 - 0.043 14.1 1.0 0.17 12.2 0.4 2.4 3 0 0 3 3 3 0 PE family efThoc1 PF11957.8 EAU85672.1 - 0.044 12.5 0.0 0.06 12.0 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Arrestin_N PF00339.29 EAU85672.1 - 0.13 12.3 0.0 0.45 10.6 0.0 1.8 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain PRiA4_ORF3 PF07929.11 EAU85675.2 - 1.3e-21 77.0 0.2 2.1e-21 76.4 0.2 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 EAU85675.2 - 3e-11 43.2 10.8 4.9e-11 42.5 10.8 1.3 1 0 0 1 1 1 1 MYND finger Med22 PF06179.12 EAU85676.1 - 3.5e-21 75.4 3.5 5.8e-21 74.7 3.5 1.4 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Exonuc_VII_L PF02601.15 EAU85678.1 - 0.077 12.5 4.7 0.11 12.0 4.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG5 PF10392.9 EAU85678.1 - 0.11 12.7 4.2 5.4 7.2 0.2 2.6 3 0 0 3 3 3 0 Golgi transport complex subunit 5 Syntaxin PF00804.25 EAU85678.1 - 0.2 11.3 6.9 0.72 9.5 0.7 3.1 3 0 0 3 3 3 0 Syntaxin NOA36 PF06524.12 EAU85678.1 - 0.35 10.1 3.6 0.51 9.6 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein PX PF00787.24 EAU85679.1 - 0.017 15.1 0.1 0.092 12.7 0.1 2.3 1 1 0 1 1 1 0 PX domain PB1 PF00564.24 EAU85679.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Actin PF00022.19 EAU85680.2 - 4.4e-37 127.7 0.0 2.1e-35 122.1 0.0 2.8 1 1 0 1 1 1 1 Actin Alpha_kinase PF02816.18 EAU85681.1 - 1.6e-05 25.1 0.5 2.4e-05 24.5 0.3 1.4 2 0 0 2 2 2 1 Alpha-kinase family MraZ PF02381.18 EAU85681.1 - 0.2 11.7 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like IL34 PF15036.6 EAU85684.2 - 0.056 13.5 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 zf-CCHC PF00098.23 EAU85686.1 - 0.044 13.9 7.8 0.17 12.0 1.5 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EAU85686.1 - 0.33 10.7 5.3 0.69 9.7 1.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Zn_ribbon_SprT PF17283.2 EAU85686.1 - 2.5 8.1 7.2 1.1 9.2 4.7 1.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain KDZ PF18758.1 EAU85687.2 - 4.6e-23 82.0 0.0 5.5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Retrotran_gag_2 PF14223.6 EAU85691.2 - 1.8e-07 30.9 0.1 3.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 EAU85691.2 - 0.0054 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Pkinase PF00069.25 EAU85693.2 - 1.8e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU85693.2 - 0.00023 21.2 0.5 0.00065 19.7 0.4 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAU85693.2 - 0.00043 19.9 0.0 0.00079 19.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EAU85693.2 - 0.0089 15.4 0.0 0.02 14.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Helo_like_N PF17111.5 EAU85703.2 - 0.1 12.0 0.1 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins GMC_oxred_N PF00732.19 EAU85704.2 - 7.9e-70 235.6 0.4 1e-69 235.2 0.4 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU85704.2 - 1e-30 107.1 0.0 1.8e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU85704.2 - 8e-05 22.8 0.1 0.00071 19.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU85704.2 - 9.9e-05 21.5 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAU85704.2 - 0.00011 21.4 0.2 0.01 14.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EAU85704.2 - 0.00046 19.9 1.3 0.0039 16.8 1.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU85704.2 - 0.0049 16.1 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU85704.2 - 0.0054 16.0 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 EAU85704.2 - 0.023 15.0 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 EAU85704.2 - 0.028 13.7 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1471 PF07338.13 EAU85704.2 - 0.058 13.4 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) GMC_oxred_N PF00732.19 EAU85705.1 - 3.3e-66 223.7 0.0 4.5e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU85705.1 - 1.3e-07 32.3 0.0 2.5e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Ntox37 PF15535.6 EAU85705.1 - 0.063 13.7 0.4 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin 37 GMC_oxred_C PF05199.13 EAU85706.1 - 1.4e-14 54.9 0.1 1.5e-14 54.8 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase DUF2076 PF09849.9 EAU85708.1 - 0.13 12.3 14.3 0.16 12.0 14.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Glyoxalase PF00903.25 EAU85709.1 - 0.00091 19.4 0.0 0.0029 17.8 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EAU85709.1 - 0.0011 19.7 0.0 0.0015 19.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Tudor-knot PF11717.8 EAU85709.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-H2C2_5 PF13909.6 EAU85710.2 - 0.0064 16.2 3.4 0.21 11.4 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain TAXi_N PF14543.6 EAU85710.2 - 4.4 7.5 7.5 8.1 6.6 7.5 1.6 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal zf-H2C2_5 PF13909.6 EAU85711.1 - 1.2e-05 24.9 0.9 0.0084 15.8 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EAU85711.1 - 0.0015 18.9 1.1 0.0015 18.9 1.1 2.7 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU85711.1 - 0.003 17.9 0.1 0.003 17.9 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU85711.1 - 0.0044 17.7 7.0 0.84 10.6 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger IBR PF01485.21 EAU85711.1 - 0.03 14.5 0.1 0.055 13.7 0.1 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.12 EAU85711.1 - 0.9 9.9 3.6 2.6 8.4 3.6 1.8 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding OrsD PF12013.8 EAU85711.1 - 2.4 8.6 9.1 1.2 9.5 0.3 3.1 3 1 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D Ribosomal_L23eN PF03939.13 EAU85713.2 - 2.1e-23 82.2 9.5 2.1e-23 82.2 9.5 3.0 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EAU85713.2 - 1.9e-15 57.0 3.1 1.9e-15 57.0 3.1 2.5 2 1 0 2 2 2 1 Ribosomal protein L23 TFIIA PF03153.13 EAU85713.2 - 1.1 9.2 5.5 1.2 9.0 5.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.7 EAU85721.2 - 0.029 14.2 0.5 0.073 13.0 0.1 1.9 2 0 0 2 2 2 0 F-box-like BTB PF00651.31 EAU85722.2 - 1.1e-09 38.5 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Transket_pyr PF02779.24 EAU85723.2 - 1.4e-65 220.3 0.0 2.2e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EAU85723.2 - 6.5e-61 205.9 0.0 9.8e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EAU85723.2 - 4.6e-52 175.8 0.0 8e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EAU85723.2 - 1.3e-17 63.1 0.7 2.7e-17 62.1 0.7 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus F-box-like PF12937.7 EAU85724.2 - 0.0025 17.7 0.0 0.007 16.2 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU85725.1 - 7.9e-05 22.5 0.0 0.00019 21.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like PKcGMP_CC PF16808.5 EAU85725.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase F-box-like PF12937.7 EAU85730.1 - 0.0021 17.9 1.4 0.0049 16.7 0.3 2.3 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU85731.1 - 4.3e-05 23.3 0.3 0.00019 21.2 0.3 2.2 1 1 0 1 1 1 1 F-box-like Ank_2 PF12796.7 EAU85732.2 - 7.4e-42 141.8 0.0 2.3e-12 47.3 0.0 5.9 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU85732.2 - 1.4e-25 89.3 0.4 2e-07 31.4 0.0 7.0 4 1 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU85732.2 - 2.3e-23 81.5 0.1 0.082 13.4 0.0 9.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 EAU85732.2 - 3.1e-23 79.3 0.1 0.0038 17.6 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAU85732.2 - 4.2e-22 77.9 1.8 2.6e-06 27.6 0.0 7.4 3 2 4 7 7 7 5 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU85732.2 - 8.7e-05 22.8 0.0 0.00027 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU85732.2 - 0.0004 20.4 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU85732.2 - 0.0026 18.2 0.0 0.009 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EAU85732.2 - 0.059 12.6 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EAU85732.2 - 0.13 11.4 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain adh_short PF00106.25 EAU85733.2 - 2.3e-42 144.7 2.7 1.6e-26 93.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU85733.2 - 1.2e-30 106.8 5.1 3.4e-17 62.8 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU85733.2 - 0.0001 22.3 1.2 0.042 13.8 0.2 2.3 2 0 0 2 2 2 2 KR domain DUF3012 PF11216.8 EAU85733.2 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) TerB_C PF15615.6 EAU85733.2 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 TerB-C domain DIT1_PvcA PF05141.12 EAU85733.2 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein AlaDh_PNT_C PF01262.21 EAU85733.2 - 1.3 8.3 4.3 1.2 8.4 1.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ZapB PF06005.12 EAU85736.2 - 0.0036 17.7 2.3 0.0036 17.7 2.3 3.0 2 1 1 3 3 3 1 Cell division protein ZapB Shugoshin_C PF07557.11 EAU85736.2 - 0.014 15.2 1.8 0.014 15.2 1.8 2.6 2 0 0 2 2 2 0 Shugoshin C terminus CENP-H PF05837.12 EAU85736.2 - 0.029 14.8 0.4 0.029 14.8 0.4 3.2 3 0 0 3 3 3 0 Centromere protein H (CENP-H) MbeD_MobD PF04899.12 EAU85736.2 - 0.14 12.3 8.8 0.86 9.8 2.5 2.5 1 1 1 2 2 2 0 MbeD/MobD like DUF3450 PF11932.8 EAU85736.2 - 0.39 10.0 18.2 2.6 7.3 17.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3552 PF12072.8 EAU85736.2 - 0.5 9.8 20.8 0.015 14.7 14.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Sec34 PF04136.15 EAU85736.2 - 0.54 10.1 3.4 0.15 12.0 0.4 1.5 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 EAU85736.2 - 0.57 10.2 4.0 0.34 10.9 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pilin PF00114.19 EAU85736.2 - 4.3 8.3 11.8 0.98 10.4 7.9 2.0 1 1 1 2 2 2 0 Pilin (bacterial filament) GAS PF13851.6 EAU85736.2 - 4.6 6.5 11.8 1 8.7 7.9 1.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 EAU85736.2 - 5.1 7.8 18.7 0.24 12.0 1.2 3.3 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 EAU85736.2 - 9.5 5.7 15.5 15 5.0 15.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit TPR_12 PF13424.6 EAU85739.2 - 9.2e-09 35.5 0.4 3.4e-06 27.3 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat NACHT PF05729.12 EAU85739.2 - 3e-06 27.2 0.0 9.1e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EAU85739.2 - 1.4e-05 24.4 0.0 5.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.17 EAU85739.2 - 1.5e-05 24.8 5.0 2.8 8.3 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Baculo_PEP_C PF04513.12 EAU85739.2 - 0.0008 19.5 2.2 0.0022 18.0 0.9 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 EAU85739.2 - 0.0017 18.6 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU85739.2 - 0.0032 17.9 0.0 0.015 15.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAU85739.2 - 0.018 15.4 0.0 0.1 13.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_19 PF14559.6 EAU85739.2 - 0.059 13.9 0.0 0.54 10.8 0.0 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU85739.2 - 0.075 12.9 1.3 9 6.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Nod1 PF17114.5 EAU85739.2 - 0.078 13.1 0.6 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 EzrA PF06160.12 EAU85739.2 - 0.13 10.4 1.8 0.63 8.2 0.1 2.3 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA TPR_9 PF13371.6 EAU85739.2 - 0.25 11.5 1.0 2.6 8.3 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 EAU85739.2 - 0.26 11.7 1.5 0.65 10.5 0.1 2.4 3 0 0 3 3 1 0 Snapin/Pallidin NPV_P10 PF05531.12 EAU85739.2 - 0.48 10.9 6.3 2.4 8.7 0.4 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EAU85739.2 - 1.1 9.3 3.8 8.2 6.5 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NCA2 PF08637.10 EAU85740.2 - 1.1e-70 238.1 0.2 4.8e-60 203.2 0.2 2.7 2 1 0 2 2 2 2 ATP synthase regulation protein NCA2 DUF1835 PF08874.10 EAU85740.2 - 0.043 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) TPR_12 PF13424.6 EAU85741.1 - 1.6e-07 31.5 0.7 4.3e-05 23.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_16 PF13191.6 EAU85741.1 - 0.00013 22.3 1.6 0.0011 19.4 0.1 3.2 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 EAU85741.1 - 0.00052 20.0 0.0 0.0021 18.0 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 EAU85741.1 - 0.00091 19.7 0.0 0.0033 17.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SNAP PF14938.6 EAU85741.1 - 0.0022 17.5 0.1 0.0041 16.6 0.1 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP AAA_22 PF13401.6 EAU85741.1 - 0.0058 16.9 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EAU85741.1 - 0.018 14.3 0.0 0.045 12.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TPR_19 PF14559.6 EAU85741.1 - 0.026 15.0 0.1 0.17 12.4 0.1 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.9 EAU85741.1 - 0.048 13.4 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 EAU85741.1 - 0.058 13.6 0.6 4.5 7.7 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU85741.1 - 0.084 13.0 0.9 4.9 7.5 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1033 PF06279.11 EAU85741.1 - 0.12 12.6 0.1 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) TPR_1 PF00515.28 EAU85741.1 - 0.21 11.5 0.8 2.6 8.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat EzrA PF06160.12 EAU85741.1 - 1.6 6.8 6.5 0.3 9.2 0.4 2.4 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA GST_N_3 PF13417.6 EAU85742.1 - 1.7e-10 41.2 0.2 8.3e-10 39.0 0.1 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU85742.1 - 3.7e-08 33.5 0.0 8.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU85742.1 - 4.1e-05 23.7 0.3 0.00016 21.8 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU85742.1 - 0.00042 20.3 0.1 0.001 19.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAU85742.1 - 0.098 13.0 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NMO PF03060.15 EAU85743.2 - 2.7e-55 188.1 0.3 2.2e-54 185.1 0.3 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EAU85743.2 - 7.4e-10 38.3 0.0 0.00012 21.2 0.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 EAU85743.2 - 0.029 13.7 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase His_biosynth PF00977.21 EAU85743.2 - 0.038 13.4 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.18 EAU85743.2 - 0.098 11.7 0.6 0.15 11.0 0.6 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase FXMRP1_C_core PF12235.8 EAU85744.1 - 7.1 7.3 15.2 6.9 7.3 8.6 2.5 2 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal TPR_12 PF13424.6 EAU85746.1 - 2.4e-10 40.6 5.7 3.7e-05 23.9 0.4 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 EAU85746.1 - 3.5e-05 24.3 0.6 0.00062 20.2 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain TPR_2 PF07719.17 EAU85746.1 - 0.0014 18.6 15.2 0.23 11.6 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 EAU85746.1 - 0.017 15.5 0.1 0.083 13.3 0.1 2.2 2 0 0 2 2 1 0 Snapin/Pallidin EzrA PF06160.12 EAU85746.1 - 0.018 13.2 1.1 0.83 7.7 0.0 2.6 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Baculo_PEP_C PF04513.12 EAU85746.1 - 0.024 14.7 0.8 0.078 13.0 0.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NB-ARC PF00931.22 EAU85746.1 - 0.032 13.4 0.0 0.099 11.8 0.0 1.9 1 0 0 1 1 1 0 NB-ARC domain TPR_14 PF13428.6 EAU85746.1 - 0.05 14.4 8.5 1 10.3 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU85746.1 - 0.073 13.3 1.5 3.4 8.0 0.1 3.2 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EAU85746.1 - 0.075 12.9 1.2 2.3 8.2 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_25 PF13481.6 EAU85746.1 - 0.093 12.3 0.2 18 4.8 0.1 2.9 1 1 1 2 2 2 0 AAA domain TPR_6 PF13174.6 EAU85746.1 - 0.094 13.4 1.5 96 4.0 0.2 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Nod1 PF17114.5 EAU85746.1 - 0.11 12.6 0.3 0.42 10.7 0.0 2.1 2 0 0 2 2 1 0 Gef2-related medial cortical node protein Nod1 GRAM PF02893.20 EAU85746.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 GRAM domain TPR_19 PF14559.6 EAU85746.1 - 0.42 11.2 5.0 0.76 10.3 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU85746.1 - 1.5 9.3 4.3 61 4.2 0.2 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 EAU85747.2 - 1.1e-11 44.7 0.1 1.1e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 EAU85748.1 - 3.8e-12 46.2 0.0 4.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AhpC-TSA PF00578.21 EAU85749.1 - 6.7e-27 93.9 0.0 8.3e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAU85749.1 - 2.8e-14 53.1 0.0 3.6e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EAU85749.1 - 0.065 13.3 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ribosomal_S19e PF01090.19 EAU85750.1 - 8.2e-59 197.2 0.1 9.4e-59 197.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.7 EAU85751.1 - 6.3e-11 42.0 0.7 1.7e-10 40.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85751.1 - 0.0019 18.0 1.2 0.015 15.1 1.2 2.6 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU85752.2 - 1.8e-08 34.1 0.2 4.5e-08 32.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85752.2 - 0.024 14.5 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain VWA PF00092.28 EAU85754.2 - 8.3e-10 39.2 0.0 1.6e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAU85754.2 - 6.4e-06 26.8 0.0 1.6e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Tautomerase PF01361.21 EAU85754.2 - 0.13 12.2 0.1 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 Tautomerase enzyme EF_assoc_2 PF08356.12 EAU85755.2 - 4.1e-36 122.8 0.0 8.3e-36 121.9 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EAU85755.2 - 2.4e-31 107.1 0.4 1e-30 105.1 0.4 2.1 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 EAU85755.2 - 7.5e-31 106.9 0.0 1.5e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAU85755.2 - 7.2e-18 65.0 0.0 5.3e-10 39.6 0.0 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 EAU85755.2 - 3.1e-11 42.3 0.2 0.00012 21.7 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EAU85755.2 - 1.4e-10 39.9 2.3 0.00032 20.0 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EAU85755.2 - 1.7e-10 41.2 0.1 0.00013 22.3 0.0 3.2 3 1 0 3 3 3 2 EF-hand domain pair Arf PF00025.21 EAU85755.2 - 1.3e-09 37.8 0.0 0.00042 19.8 0.0 2.9 2 2 0 2 2 2 2 ADP-ribosylation factor family EF-hand_5 PF13202.6 EAU85755.2 - 5.6e-08 31.9 3.7 0.0058 16.1 0.1 2.8 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 EAU85755.2 - 2.2e-07 30.9 0.1 0.0015 18.6 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EAU85755.2 - 4.5e-06 27.0 0.3 0.11 12.8 0.2 3.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EAU85755.2 - 1.4e-05 25.6 0.2 0.29 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EAU85755.2 - 2.3e-05 24.9 0.0 0.063 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EAU85755.2 - 4e-05 23.6 0.2 0.16 11.9 0.0 3.6 4 0 0 4 4 3 1 RsgA GTPase ABC_tran PF00005.27 EAU85755.2 - 4.7e-05 23.9 0.0 0.24 11.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_24 PF13479.6 EAU85755.2 - 5.4e-05 23.0 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAU85755.2 - 0.00011 21.9 0.1 0.068 12.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 EAU85755.2 - 0.00012 22.2 1.9 0.29 11.2 0.0 3.2 2 1 1 3 3 3 1 Dynamin family AAA_28 PF13521.6 EAU85755.2 - 0.00019 21.7 0.0 0.26 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAU85755.2 - 0.00025 21.2 0.4 0.71 10.0 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 EAU85755.2 - 0.00026 21.4 0.1 0.47 10.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAU85755.2 - 0.00052 20.0 0.1 0.53 10.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain Septin PF00735.18 EAU85755.2 - 0.00065 19.1 0.0 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 Septin AAA_7 PF12775.7 EAU85755.2 - 0.0016 18.0 0.1 0.051 13.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region G-alpha PF00503.20 EAU85755.2 - 0.0017 17.6 0.0 1.9 7.6 0.0 2.6 3 0 0 3 3 2 2 G-protein alpha subunit EF-hand_10 PF14788.6 EAU85755.2 - 0.0021 17.9 0.7 0.013 15.3 0.1 2.2 2 0 0 2 2 2 1 EF hand RNA_helicase PF00910.22 EAU85755.2 - 0.0022 18.4 0.0 0.98 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 EAU85755.2 - 0.0032 17.2 0.0 0.77 9.5 0.1 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 EAU85755.2 - 0.0036 17.0 0.0 0.56 10.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation EF-hand_8 PF13833.6 EAU85755.2 - 0.0054 16.6 1.0 1.8 8.5 0.1 3.1 3 0 0 3 3 2 1 EF-hand domain pair ATP_bind_1 PF03029.17 EAU85755.2 - 0.0062 16.3 3.9 8.7 6.0 0.3 4.0 3 1 0 4 4 4 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EAU85755.2 - 0.0064 15.7 0.0 0.62 9.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain VirE PF05272.11 EAU85755.2 - 0.0064 16.2 0.0 4.9 6.8 0.0 3.4 3 1 0 3 3 3 0 Virulence-associated protein E SRPRB PF09439.10 EAU85755.2 - 0.0075 15.7 0.0 2.6 7.5 0.0 2.5 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 EAU85755.2 - 0.0081 15.8 0.0 0.58 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EAU85755.2 - 0.0092 15.2 0.1 0.72 9.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MCM PF00493.23 EAU85755.2 - 0.017 14.2 0.0 0.099 11.7 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain Zeta_toxin PF06414.12 EAU85755.2 - 0.023 14.0 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NOG1 PF06858.14 EAU85755.2 - 0.025 14.3 0.2 2.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AIG1 PF04548.16 EAU85755.2 - 0.028 13.8 0.0 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family SPARC_Ca_bdg PF10591.9 EAU85755.2 - 0.03 14.7 1.8 0.79 10.1 0.0 3.0 3 1 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ploopntkinase3 PF18751.1 EAU85755.2 - 0.034 14.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 EAU85755.2 - 0.041 13.2 0.1 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 EAU85755.2 - 0.042 13.9 0.0 6.1 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EAU85755.2 - 0.046 13.3 0.6 3.7 7.1 0.1 3.0 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EAU85755.2 - 0.05 14.1 1.6 7 7.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_9 PF14658.6 EAU85755.2 - 0.051 13.9 0.0 3.3 8.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain TsaE PF02367.17 EAU85755.2 - 0.052 13.6 0.0 8.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EAU85755.2 - 0.055 13.2 0.1 2.4 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAU85755.2 - 0.065 13.2 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 EAU85755.2 - 0.073 12.8 0.1 0.31 10.7 0.1 2.0 2 0 0 2 2 2 0 Guanylate kinase Pox_A32 PF04665.12 EAU85755.2 - 0.078 12.4 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein TniB PF05621.11 EAU85755.2 - 0.1 12.0 0.0 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 EAU85755.2 - 0.1 12.5 0.1 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 EAU85755.2 - 0.23 11.1 0.0 24 4.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF4126 PF13548.6 EAU85755.2 - 0.5 10.0 3.8 0.14 11.8 0.9 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4126) F-box-like PF12937.7 EAU85756.2 - 4.3e-06 26.5 0.5 9.4e-06 25.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU85756.2 - 1.4e-05 24.8 0.4 2.7e-05 23.9 0.4 1.5 1 0 0 1 1 1 1 F-box domain RasGEF PF00617.19 EAU85757.2 - 1.3e-48 165.5 0.0 2.3e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAU85757.2 - 1.8e-20 73.1 0.0 5.5e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EAU85757.2 - 1.4e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU85757.2 - 3.2e-12 45.9 0.0 6.8e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAU85757.2 - 1.6e-11 43.6 0.0 2.9e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain MalF_P2 PF14785.6 EAU85757.2 - 0.15 12.1 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain OHCU_decarbox PF09349.10 EAU85757.2 - 0.16 12.4 1.2 0.49 10.9 0.1 2.2 2 0 0 2 2 2 0 OHCU decarboxylase Focal_AT PF03623.13 EAU85757.2 - 0.19 11.7 0.1 0.9 9.5 0.1 2.1 2 0 0 2 2 2 0 Focal adhesion targeting region Nas2_N PF18265.1 EAU85758.2 - 6.4e-28 96.5 0.0 8.7e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 EAU85758.2 - 0.00081 19.7 0.0 0.0015 18.8 0.0 1.7 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EAU85758.2 - 0.0053 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Thi4 PF01946.17 EAU85759.2 - 2.1e-103 344.6 0.1 2.5e-103 344.4 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAU85759.2 - 3.2e-09 36.9 4.3 2.5e-08 33.9 1.7 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAU85759.2 - 4.6e-07 29.2 1.1 3.9e-06 26.2 0.4 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EAU85759.2 - 6.5e-07 28.9 0.1 9.1e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU85759.2 - 1.6e-06 28.2 0.2 4.3e-06 26.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU85759.2 - 4.6e-06 26.0 4.1 5.2e-05 22.5 1.2 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EAU85759.2 - 2.7e-05 23.7 0.4 3.8e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAU85759.2 - 8.9e-05 22.5 4.2 0.00028 20.9 0.1 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EAU85759.2 - 0.0016 17.2 0.9 0.0031 16.3 0.6 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EAU85759.2 - 0.016 14.3 0.2 0.14 11.2 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EAU85759.2 - 0.021 14.1 0.3 0.045 13.0 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAU85759.2 - 0.045 12.6 0.4 0.07 12.0 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.19 EAU85759.2 - 0.088 12.2 0.1 3.4 6.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase CM_2 PF01817.21 EAU85760.1 - 3e-05 24.3 0.0 0.012 16.0 0.0 2.7 2 0 0 2 2 2 2 Chorismate mutase type II Septin PF00735.18 EAU85761.2 - 1.7e-47 162.1 0.2 3.6e-18 65.8 0.0 3.2 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 EAU85761.2 - 2.2e-05 24.5 0.1 5.3e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAU85761.2 - 7.9e-05 22.3 0.0 0.00028 20.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAU85761.2 - 0.013 15.9 0.2 0.029 14.8 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain MID_MedPIWI PF18296.1 EAU85761.2 - 0.044 13.6 2.7 0.091 12.5 0.0 2.4 2 1 0 2 2 2 0 MID domain of medPIWI AAA_22 PF13401.6 EAU85761.2 - 0.047 14.0 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAU85761.2 - 0.075 13.5 0.6 0.39 11.2 0.5 2.2 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 EAU85761.2 - 0.089 13.2 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EAU85762.2 - 1.4e-22 80.3 0.0 4.2e-08 32.8 0.0 4.0 3 1 0 3 3 3 3 Septin Zn_clus PF00172.18 EAU85762.2 - 5.4e-19 68.0 27.2 1.1e-09 38.3 10.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EAU85763.1 - 3e-11 43.2 7.7 4.6e-11 42.7 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.21 EAU85764.1 - 1.5e-208 693.6 0.1 1.8e-208 693.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family F-box-like PF12937.7 EAU85766.2 - 0.028 14.3 0.4 0.082 12.8 0.4 1.9 1 0 0 1 1 1 0 F-box-like Cys_rich_VLP PF14194.6 EAU85766.2 - 0.5 10.5 2.5 1.3 9.2 2.5 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP RIO1 PF01163.22 EAU85767.2 - 4.4e-68 228.6 0.0 7.6e-68 227.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAU85767.2 - 2.6e-05 24.3 0.2 0.085 12.8 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EAU85767.2 - 0.0051 16.2 1.9 1 8.7 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAU85767.2 - 0.02 14.2 0.0 0.045 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain GFA PF04828.14 EAU85769.2 - 2.9e-06 27.5 14.6 0.0028 18.0 0.1 3.3 2 1 1 3 3 3 3 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 EAU85769.2 - 8.5 6.2 12.8 0.32 10.8 1.5 3.1 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF3767 PF12597.8 EAU85770.2 - 1e-18 67.0 0.0 1.3e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Rhodanese PF00581.20 EAU85771.2 - 0.00014 22.4 0.0 0.00016 22.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain SL4P PF17618.2 EAU85771.2 - 0.031 14.3 0.1 0.07 13.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Tetraspanin PF00335.20 EAU85773.1 - 2.1e-10 40.7 13.4 2.9e-10 40.2 13.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2069 PF09842.9 EAU85773.1 - 0.18 12.0 9.3 0.075 13.2 1.8 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2069) F-box-like PF12937.7 EAU85775.1 - 9.9e-07 28.6 2.6 1.2e-06 28.3 0.5 2.4 2 0 0 2 2 2 1 F-box-like GSH_synth_ATP PF03917.17 EAU85776.2 - 3.1e-130 434.3 0.0 3.6e-130 434.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EAU85776.2 - 2.2e-32 111.5 0.1 3.5e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase F-box-like PF12937.7 EAU85777.2 - 1.1e-08 34.8 4.0 1.7e-07 31.0 2.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85777.2 - 1.1 9.2 11.5 13 5.8 0.1 3.7 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EAU85779.1 - 0.00024 20.9 0.0 0.00083 19.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like Glyco_hydro_15 PF00723.21 EAU85780.2 - 1.1e-93 314.5 0.0 1.4e-93 314.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EAU85780.2 - 3e-27 94.4 0.1 5.3e-27 93.6 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain Homeodomain PF00046.29 EAU85781.1 - 1.7e-11 43.8 0.1 3.8e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EAU85781.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.6 3 0 0 3 3 3 0 Homeobox KN domain adh_short PF00106.25 EAU85783.2 - 1.5e-23 83.2 0.7 1.8e-23 83.0 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU85783.2 - 1.2e-14 54.4 0.1 1.5e-14 54.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU85783.2 - 3.8e-10 39.9 0.2 4.5e-10 39.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU85783.2 - 8.8e-05 22.1 0.1 0.00011 21.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAU85783.2 - 9.1e-05 21.7 0.1 0.00011 21.5 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EAU85783.2 - 0.0018 18.5 0.3 0.0025 18.1 0.3 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EAU85783.2 - 0.004 17.2 0.1 0.0057 16.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EAU85783.2 - 0.0085 15.5 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 EAU85783.2 - 0.0096 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 EAU85783.2 - 0.021 14.4 0.5 0.028 14.0 0.5 1.1 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 EAU85783.2 - 0.021 14.0 0.6 0.032 13.4 0.6 1.4 1 1 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.6 EAU85783.2 - 0.038 13.9 0.4 0.05 13.5 0.4 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TAF PF02969.17 EAU85784.2 - 1.1e-19 70.4 0.2 2.1e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 EAU85784.2 - 1.2e-16 60.8 0.1 3.4e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Urb2 PF10441.9 EAU85784.2 - 0.011 15.6 2.7 0.016 15.1 1.3 1.8 1 1 1 2 2 2 0 Urb2/Npa2 family HEAT_EZ PF13513.6 EAU85784.2 - 0.03 14.8 5.2 1.5 9.4 0.0 4.5 3 1 1 5 5 5 0 HEAT-like repeat Histone PF00125.24 EAU85784.2 - 0.041 14.2 0.2 0.087 13.2 0.2 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4704 PF15787.5 EAU85784.2 - 0.066 12.4 0.6 0.12 11.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) Gal-bind_lectin PF00337.22 EAU85786.2 - 3.3e-08 33.1 0.0 4.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin Thioredoxin_15 PF18403.1 EAU85786.2 - 0.13 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Gal-bind_lectin PF00337.22 EAU85788.2 - 1.3e-07 31.3 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Galactoside-binding lectin Aldo_ket_red PF00248.21 EAU85789.2 - 1.2e-67 228.2 0.0 1.4e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AsnA PF03590.15 EAU85789.2 - 0.092 12.5 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Aspartate-ammonia ligase IMPa_N_2 PF18650.1 EAU85789.2 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Ribosomal_L5_C PF00673.21 EAU85790.2 - 2.5e-25 88.5 0.0 4e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Pkinase PF00069.25 EAU85791.2 - 1e-72 244.7 0.0 2.1e-72 243.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85791.2 - 4e-51 173.8 0.0 1.2e-50 172.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU85791.2 - 0.00041 19.8 0.0 0.0035 16.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAU85791.2 - 0.0036 16.1 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EAU85791.2 - 0.18 11.4 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cas_GSU0053 PF09617.10 EAU85795.2 - 0.056 13.4 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Syntaxin_2 PF14523.6 EAU85799.1 - 5e-22 78.2 7.8 6.2e-22 77.9 2.8 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EAU85799.1 - 1.5e-09 37.7 0.1 3.6e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EAU85799.1 - 1.1e-08 35.0 9.4 2.1e-08 34.1 9.4 1.5 1 1 0 1 1 1 1 Syntaxin TMPIT PF07851.13 EAU85799.1 - 0.0065 15.8 2.2 0.81 8.9 2.2 2.1 1 1 0 1 1 1 1 TMPIT-like protein DUF2730 PF10805.8 EAU85799.1 - 0.019 15.1 2.0 1.9 8.6 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) MPS2 PF17060.5 EAU85799.1 - 0.034 13.4 2.8 0.041 13.2 2.3 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 Prominin PF05478.11 EAU85799.1 - 0.14 10.1 3.0 0.19 9.7 3.0 1.3 1 1 0 1 1 1 0 Prominin DUF2203 PF09969.9 EAU85799.1 - 1.7 9.4 5.4 3.1 8.5 0.4 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) BST2 PF16716.5 EAU85799.1 - 2.3 8.9 10.7 0.18 12.4 1.1 3.0 2 2 1 3 3 3 0 Bone marrow stromal antigen 2 Exonuc_VII_L PF02601.15 EAU85799.1 - 7.3 6.1 12.7 10 5.6 12.3 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit AMP-binding PF00501.28 EAU85801.1 - 4.4e-77 259.5 0.0 5.5e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU85801.1 - 5.3e-14 53.0 0.1 1.2e-13 51.8 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DNA_ligase_OB PF03120.16 EAU85801.1 - 0.1 12.5 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain AMP-binding PF00501.28 EAU85802.2 - 2e-64 217.8 0.0 2.4e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU85802.2 - 7.2e-13 49.3 0.0 1.7e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SepRS_C PF18006.1 EAU85802.2 - 2.1 8.5 6.3 17 5.6 0.0 3.2 3 0 0 3 3 3 0 O-phosphoseryl-tRNA synthetase C-terminal domain Duffy_binding PF05424.11 EAU85803.1 - 0.063 13.3 0.4 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Duffy binding domain FIST PF08495.10 EAU85804.1 - 1.9e-05 24.8 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 FIST N domain SNAP-25 PF00835.19 EAU85804.1 - 0.088 13.1 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 SNAP-25 family TDRP PF15683.5 EAU85807.2 - 0.013 15.4 0.7 0.024 14.6 0.7 1.3 1 0 0 1 1 1 0 Testis development-related protein Phage_holin_3_6 PF07332.11 EAU85807.2 - 0.073 13.1 0.2 0.15 12.1 0.2 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MAP17 PF15807.5 EAU85807.2 - 0.099 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2207 PF09972.9 EAU85807.2 - 0.16 10.7 0.0 1.5 7.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Carn_acyltransf PF00755.20 EAU85810.1 - 1.4e-191 638.1 0.0 1.8e-191 637.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Tyrosinase PF00264.20 EAU85812.2 - 5e-27 95.6 0.2 1.1e-26 94.5 0.2 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EAU85812.2 - 3.6e-20 72.8 0.0 6.9e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain UPF0172 PF03665.13 EAU85815.1 - 2.7e-53 180.9 0.0 3.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EAU85815.1 - 0.0047 16.9 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ssDBP PF17878.1 EAU85815.1 - 0.03 14.5 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 Single-stranded DNA-binding protein Pkinase_fungal PF17667.1 EAU85816.2 - 4.4e-26 91.6 0.0 2.6e-23 82.5 0.0 2.6 2 1 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EAU85816.2 - 0.031 14.2 0.8 0.26 11.2 0.8 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EAU85816.2 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Fungal_trans PF04082.18 EAU85818.2 - 2.3e-12 46.5 0.1 6.4e-12 45.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain CAF1 PF04857.20 EAU85819.2 - 6.6e-21 74.8 0.1 1.2e-10 41.0 0.0 2.6 1 1 1 2 2 2 2 CAF1 family ribonuclease DPBB_1 PF03330.18 EAU85822.1 - 6.4e-06 26.4 0.2 5.9e-05 23.3 0.2 2.5 1 1 0 1 1 1 1 Lytic transglycolase F-box-like PF12937.7 EAU85824.1 - 4.8e-05 23.2 0.0 0.00019 21.2 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU85825.2 - 0.0025 17.7 0.2 0.01 15.7 0.2 2.1 1 0 0 1 1 1 1 F-box-like Desulfoferrod_N PF06397.12 EAU85826.2 - 0.0061 16.2 1.0 0.033 13.8 0.1 2.1 1 1 1 2 2 2 1 Desulfoferrodoxin, N-terminal domain DPBB_1 PF03330.18 EAU85826.2 - 0.043 14.1 0.1 0.41 10.9 0.1 2.5 1 1 0 1 1 1 0 Lytic transglycolase zf-C2H2 PF00096.26 EAU85828.2 - 3.8e-05 23.9 21.5 0.01 16.3 1.9 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU85828.2 - 0.059 14.2 21.8 1.1 10.3 1.0 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 EAU85828.2 - 0.09 12.5 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 EAU85828.2 - 0.11 12.9 16.6 7.2 7.2 1.8 4.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EAU85828.2 - 0.68 9.7 24.4 0.043 13.6 3.0 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_7 PF15269.6 EAU85828.2 - 2 8.6 5.5 21 5.3 1.0 2.5 2 0 0 2 2 2 0 Zinc-finger Zn-C2H2_12 PF18112.1 EAU85828.2 - 8.8 6.9 12.0 3 8.4 0.4 3.6 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain EBP PF05241.12 EAU85829.1 - 5e-59 198.7 8.3 5.9e-59 198.5 8.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein RPAP3_C PF13877.6 EAU85830.2 - 3.3e-15 56.4 0.0 1.3e-14 54.5 0.0 1.9 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 EAU85830.2 - 5.4e-14 51.3 3.2 7.7e-06 25.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU85830.2 - 1.3e-12 46.8 5.6 0.0019 18.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAU85830.2 - 7.1e-07 29.8 8.2 1.4e-05 25.6 7.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAU85830.2 - 3.8e-06 26.9 2.0 8.4e-06 25.8 2.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU85830.2 - 4.7e-06 26.4 1.2 0.36 11.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAU85830.2 - 5e-06 26.9 7.4 0.0045 17.5 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU85830.2 - 1.7e-05 24.4 2.5 0.054 13.2 0.2 3.1 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 EAU85830.2 - 0.00036 20.7 0.3 0.049 14.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU85830.2 - 0.0005 20.7 5.8 0.08 13.8 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU85830.2 - 0.0014 18.5 0.3 0.1 12.7 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU85830.2 - 0.0017 18.6 2.5 0.003 17.8 0.8 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU85830.2 - 0.0084 16.3 0.4 0.015 15.5 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EAU85830.2 - 0.032 14.3 0.2 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CMAS PF02353.20 EAU85831.2 - 2.1e-48 165.0 0.0 1.3e-23 83.7 0.0 3.2 3 0 0 3 3 3 3 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EAU85831.2 - 1.9e-06 28.5 0.0 0.014 16.1 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EAU85831.2 - 2.8e-05 24.8 0.0 0.00049 20.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU85831.2 - 0.0029 17.5 0.0 0.0061 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU85831.2 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EAU85831.2 - 0.19 11.5 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain BUD22 PF09073.10 EAU85831.2 - 0.31 10.3 4.3 0.43 9.9 4.3 1.1 1 0 0 1 1 1 0 BUD22 Pkinase_fungal PF17667.1 EAU85832.2 - 9.8e-16 57.5 0.0 1.7e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF1902 PF08972.11 EAU85833.1 - 0.16 12.0 0.7 0.4 10.7 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) FOXP-CC PF16159.5 EAU85834.1 - 0.58 10.8 2.2 0.74 10.5 0.1 2.2 3 0 0 3 3 3 0 FOXP coiled-coil domain Sina PF03145.16 EAU85834.1 - 1.7 8.5 4.9 0.8 9.6 2.6 1.5 2 0 0 2 2 2 0 Seven in absentia protein family Transferase PF02458.15 EAU85835.1 - 3.1e-23 82.1 0.0 1.1e-21 77.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family DUF4203 PF13886.6 EAU85836.1 - 0.00052 19.7 14.2 0.00087 19.0 14.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Troponin-I_N PF11636.8 EAU85836.1 - 0.13 12.3 0.8 12 5.9 0.1 2.7 2 0 0 2 2 2 0 Troponin I residues 1-32 DUF465 PF04325.13 EAU85836.1 - 0.3 11.2 3.5 0.95 9.6 3.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) AMP-binding PF00501.28 EAU85837.2 - 7.6e-74 248.8 0.1 7.1e-44 150.1 0.0 3.0 2 1 0 2 2 2 2 AMP-binding enzyme Fic_N PF13784.6 EAU85837.2 - 0.02 14.9 0.0 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Fic/DOC family N-terminal ELFV_dehydrog PF00208.21 EAU85838.2 - 4.2e-56 190.4 0.0 6.1e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EAU85838.2 - 1.9e-20 72.2 0.0 4e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase DIOX_N PF14226.6 EAU85839.2 - 1.5e-30 106.4 0.0 2.2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAU85839.2 - 2.3e-23 82.6 0.0 4.6e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 EAU85840.2 - 1.2e-27 96.7 0.0 6.6e-19 68.1 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU85840.2 - 4e-20 72.4 0.0 2.7e-11 43.5 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU85840.2 - 5.4e-07 29.7 0.3 1.2e-06 28.6 0.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU85840.2 - 0.0023 17.5 0.1 0.0039 16.7 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAU85840.2 - 0.012 15.0 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EAU85840.2 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.27 EAU85840.2 - 0.082 13.5 0.5 0.13 12.8 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU85841.1 - 2.7e-52 177.8 0.1 3.1e-52 177.6 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU85841.1 - 5.6e-18 65.3 0.3 6.5e-15 55.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU85841.1 - 2.6e-17 63.1 0.2 1.3e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU85841.1 - 3.3e-06 26.5 0.0 1.7e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EAU85841.1 - 0.00017 21.7 0.3 0.0083 16.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EAU85841.1 - 0.00038 19.7 6.2 0.0065 15.6 0.1 4.0 4 1 1 5 5 5 1 Glucose inhibited division protein A DAO PF01266.24 EAU85841.1 - 0.0005 19.8 1.8 0.24 10.9 0.3 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAU85841.1 - 0.00059 19.0 2.1 0.0064 15.6 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 EAU85841.1 - 0.00081 19.8 0.1 0.14 12.6 0.0 3.0 2 2 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.7 EAU85841.1 - 0.0011 18.4 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAU85841.1 - 0.0017 17.6 0.1 0.019 14.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.6 EAU85841.1 - 0.0021 17.3 0.1 0.5 9.5 0.0 3.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EAU85841.1 - 0.0053 16.8 0.8 5.2 7.1 0.0 3.3 3 1 1 4 4 4 1 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EAU85841.1 - 0.0091 14.9 0.1 0.051 12.4 0.1 2.1 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 EAU85841.1 - 0.0095 14.7 1.2 0.066 11.9 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein F420_oxidored PF03807.17 EAU85841.1 - 0.023 15.3 0.0 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 EAU85841.1 - 0.047 13.7 0.1 17 5.3 0.0 2.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 EAU85841.1 - 0.083 12.5 0.8 17 5.0 0.1 2.9 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA GPI-anchored PF10342.9 EAU85842.2 - 0.00074 20.2 0.0 0.0014 19.3 0.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 EAU85843.2 - 1e-08 35.8 0.1 1.8e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 EAU85843.2 - 0.072 12.9 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) zf-C2H2 PF00096.26 EAU85844.2 - 2.5e-08 33.9 13.3 0.003 17.9 0.3 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EAU85844.2 - 3.2e-08 33.2 12.0 0.00071 19.3 0.2 4.0 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-Di19 PF05605.12 EAU85844.2 - 9.6e-05 22.6 5.9 0.0055 17.0 2.2 2.3 1 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EAU85844.2 - 0.00081 19.7 12.4 0.21 12.1 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU85844.2 - 0.0016 19.1 14.1 0.22 12.5 0.9 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EAU85844.2 - 0.0051 17.0 1.7 0.21 11.7 0.5 2.1 1 1 1 2 2 2 2 Aberrant zinc-finger zf-C2H2_12 PF18658.1 EAU85844.2 - 0.014 15.0 1.3 0.24 11.0 0.3 2.3 1 1 0 2 2 2 0 Zinc-finger C2H2-type NtCtMGAM_N PF16863.5 EAU85844.2 - 0.094 12.9 0.0 1.3 9.2 0.0 2.2 1 1 1 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase zf-C2H2_8 PF15909.5 EAU85844.2 - 0.16 12.3 2.6 1.3 9.4 2.0 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon F-box-like PF12937.7 EAU85845.1 - 0.00034 20.5 0.7 0.0011 18.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU85845.1 - 0.015 15.2 1.7 0.15 12.0 0.4 2.9 2 1 0 2 2 2 0 F-box domain NACHT PF05729.12 EAU85846.2 - 1.2e-08 35.0 0.0 3.1e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU85846.2 - 4.1e-07 30.5 0.0 9.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAU85846.2 - 7.1e-05 22.8 0.0 0.001 19.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EAU85846.2 - 7.2e-05 22.2 0.0 0.0018 17.5 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.6 EAU85846.2 - 0.0059 16.9 0.0 0.022 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAU85846.2 - 0.0076 16.6 0.0 0.048 14.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EAU85846.2 - 0.03 13.8 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 EAU85846.2 - 0.14 12.6 0.1 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EAU85846.2 - 0.19 10.9 0.0 6.1 6.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Pkinase PF00069.25 EAU85847.2 - 1.4e-08 34.4 0.0 1e-07 31.6 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85847.2 - 0.0015 17.9 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU85847.2 - 0.043 12.6 0.0 0.048 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EAU85847.2 - 0.046 13.6 0.4 1.2 9.0 0.5 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.7 EAU85848.2 - 0.014 15.2 2.3 0.051 13.5 2.3 2.0 1 1 0 1 1 1 0 F-box-like F-box PF00646.33 EAU85848.2 - 0.12 12.3 0.7 1.9 8.4 0.7 2.7 1 1 0 1 1 1 0 F-box domain LRR_6 PF13516.6 EAU85848.2 - 0.83 9.9 4.4 14 6.0 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat Cep57_MT_bd PF06657.13 EAU85851.2 - 9.2e-21 74.1 0.1 9.2e-21 74.1 0.1 4.0 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EAU85851.2 - 1.2e-10 41.4 9.0 1.2e-10 41.4 9.0 3.7 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 Pox_A_type_inc PF04508.12 EAU85851.2 - 0.68 9.9 9.0 0.31 11.0 2.1 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4200 PF13863.6 EAU85851.2 - 1.5 9.3 25.2 0.043 14.2 14.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) BTB PF00651.31 EAU85853.1 - 1.7e-10 41.1 0.0 3.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Helitron_like_N PF14214.6 EAU85854.2 - 3.6e-13 50.2 0.0 4.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4191 PF13829.6 EAU85854.2 - 0.11 11.8 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Tcp11 PF05794.13 EAU85859.2 - 5.9e-80 269.5 0.0 1.6e-79 268.1 0.0 1.6 1 1 0 1 1 1 1 T-complex protein 11 ATP-synt_ab PF00006.25 EAU85860.1 - 7.2e-67 225.1 0.0 1e-66 224.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EAU85860.1 - 4.6e-11 43.1 0.7 8.3e-11 42.3 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain TFCD_C PF12612.8 EAU85861.2 - 1.2e-41 142.6 0.1 1.1e-40 139.5 0.0 2.5 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 EAU85861.2 - 0.00044 20.6 4.9 3.6 8.0 0.0 5.1 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EAU85861.2 - 0.0067 16.6 4.2 0.4 11.1 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EAU85861.2 - 0.05 14.2 0.0 0.91 10.2 0.0 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Isy1 PF06246.12 EAU85861.2 - 0.13 11.8 0.4 12 5.4 0.1 2.4 2 0 0 2 2 2 0 Isy1-like splicing family Cnd1 PF12717.7 EAU85861.2 - 0.16 12.0 0.0 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CHDCT2 PF08074.11 EAU85861.2 - 0.18 12.0 0.3 0.6 10.3 0.1 2.0 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain BUD22 PF09073.10 EAU85862.2 - 5.7e-92 309.3 28.6 6.5e-92 309.1 28.6 1.0 1 0 0 1 1 1 1 BUD22 PP1_inhibitor PF05361.12 EAU85862.2 - 0.02 14.9 0.4 0.047 13.7 0.4 1.6 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Efg1 PF10153.9 EAU85862.2 - 0.15 12.4 3.4 0.76 10.2 3.4 2.4 1 1 0 1 1 1 0 rRNA-processing protein Efg1 PP2C PF00481.21 EAU85866.2 - 1.3e-66 224.8 0.0 1.6e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EAU85866.2 - 0.036 13.7 0.0 0.058 13.0 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C PBSX_XtrA PF17356.2 EAU85866.2 - 0.085 12.8 0.0 1.3 9.0 0.0 2.5 3 0 0 3 3 3 0 Phage-like element PBSX protein XtrA CS PF04969.16 EAU85867.2 - 4.1e-10 40.5 0.1 7e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 CS domain DUF727 PF05303.12 EAU85868.2 - 0.0005 20.1 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) OGFr_N PF04664.13 EAU85869.1 - 8.7e-58 195.3 0.6 1e-57 195.0 0.6 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Tam41_Mmp37 PF09139.11 EAU85871.2 - 3e-114 381.8 0.0 3.5e-114 381.6 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial POX PF07526.11 EAU85872.2 - 0.14 12.7 0.7 0.25 11.9 0.7 1.3 1 0 0 1 1 1 0 Associated with HOX ATG16 PF08614.11 EAU85872.2 - 0.2 11.9 3.4 0.29 11.3 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Striatin PF08232.12 EAU85872.2 - 0.45 11.1 4.5 0.61 10.7 4.5 1.2 1 0 0 1 1 1 0 Striatin family YTH PF04146.15 EAU85874.2 - 3.2e-58 196.4 0.0 7.9e-58 195.1 0.0 1.7 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 EAU85874.2 - 3.9e-06 26.6 0.0 6.2e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EAU85875.2 - 8e-20 70.8 1.0 0.006 17.4 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU85875.2 - 7.8e-08 32.5 0.0 0.58 10.5 0.0 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EAU85875.2 - 0.0013 18.4 0.0 0.0036 16.9 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.11 EAU85875.2 - 0.0048 16.8 0.4 3.2 7.6 0.0 3.2 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EAU85875.2 - 0.0076 14.9 0.1 0.1 11.2 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EAU85875.2 - 0.065 12.2 0.5 2.9 6.8 0.1 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EAU85875.2 - 0.1 11.1 0.0 0.22 10.0 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain RNase_H_2 PF13482.6 EAU85876.2 - 0.0089 16.0 0.1 2.8 7.9 0.0 2.2 2 0 0 2 2 2 2 RNase_H superfamily Pkinase PF00069.25 EAU85877.2 - 1e-41 143.1 0.0 2e-41 142.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU85877.2 - 2.9e-21 75.9 0.0 1e-20 74.1 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAU85877.2 - 5.2e-05 23.3 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU85877.2 - 0.00023 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAU85877.2 - 0.022 14.4 0.1 0.07 12.7 0.1 1.8 1 0 0 1 1 1 0 RIO1 family Macoilin PF09726.9 EAU85877.2 - 0.35 9.4 12.2 0.57 8.7 12.2 1.2 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 EAU85877.2 - 0.42 8.9 5.3 0.6 8.3 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 EAU85877.2 - 2.4 7.5 14.7 1.1 8.6 9.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) HisG PF01634.18 EAU85878.2 - 2.9e-53 180.1 0.0 3.9e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EAU85878.2 - 1.3e-26 92.5 0.1 2.5e-26 91.6 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EAU85878.2 - 0.0014 18.6 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Rot1 PF10681.9 EAU85880.1 - 6.5e-55 185.9 0.0 7.2e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Proteasome PF00227.26 EAU85881.2 - 1.1e-32 113.1 0.0 1.3e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit RPN1_C PF18051.1 EAU85881.2 - 0.083 12.9 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal ADH_N PF08240.12 EAU85885.1 - 1.9e-23 82.4 1.1 2.8e-23 81.9 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU85885.1 - 9.4e-09 35.3 0.0 1.9e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_9 PF13454.6 EAU85885.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding TAN PF11640.8 EAU85886.2 - 0.055 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair YL1 PF05764.13 EAU85890.1 - 0.0069 16.5 0.6 0.0081 16.3 0.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein zf-C2H2_4 PF13894.6 EAU85890.1 - 0.0099 16.6 1.6 2.5 9.2 0.1 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HE PF16278.5 EAU85890.1 - 0.057 13.9 0.0 0.5 10.8 0.0 2.3 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EAU85890.1 - 0.11 12.9 0.3 3.9 8.0 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EAU85890.1 - 0.13 12.7 0.1 0.13 12.7 0.1 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type Sporozoite_P67 PF05642.11 EAU85890.1 - 0.23 9.5 3.0 0.29 9.2 3.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FHA PF00498.26 EAU85891.2 - 5.3e-18 65.1 0.0 9.4e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EAU85891.2 - 7.6e-08 32.6 0.0 0.003 17.8 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Zn_clus PF00172.18 EAU85892.2 - 2e-08 34.2 10.5 4e-08 33.2 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CRD PF17979.1 EAU85893.1 - 1.5e-09 38.2 0.0 1.5e-09 38.2 0.0 2.4 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-RING_2 PF13639.6 EAU85893.1 - 8.7e-06 26.0 12.7 8.7e-06 26.0 12.7 3.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU85893.1 - 1.1e-05 25.1 12.5 1.1e-05 25.1 12.5 3.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU85893.1 - 0.00011 21.9 9.5 0.00011 21.9 9.5 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU85893.1 - 0.0003 20.6 10.9 0.0003 20.6 10.9 3.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 EAU85893.1 - 0.00072 19.5 0.4 0.0017 18.3 0.4 1.6 1 0 0 1 1 1 1 PBZ domain CpXC PF14353.6 EAU85893.1 - 0.96 9.5 4.5 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 CpXC protein Kelch_6 PF13964.6 EAU85894.2 - 3.9e-25 87.2 3.5 2.2e-08 34.1 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 EAU85894.2 - 1.1e-16 60.2 2.3 0.00033 20.2 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EAU85894.2 - 1e-15 57.5 1.3 4.3e-05 23.4 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EAU85894.2 - 2.4e-15 56.4 1.7 3.1e-08 33.7 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EAU85894.2 - 2.6e-15 56.0 0.3 0.00074 19.4 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EAU85894.2 - 2.7e-14 52.5 4.5 0.0022 17.9 0.0 5.1 4 1 0 4 4 4 3 Kelch motif BTB PF00651.31 EAU85894.2 - 0.044 14.0 0.3 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Putative_PNPOx PF01243.20 EAU85895.2 - 2e-23 82.4 0.1 3.4e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EAU85895.2 - 1.9e-05 25.2 0.1 4.1e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EAU85895.2 - 0.026 14.5 0.2 0.049 13.6 0.2 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EAU85895.2 - 0.033 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Rep_fac-A_3 PF08661.11 EAU85895.2 - 0.16 12.4 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Replication factor A protein 3 SIKE PF05769.11 EAU85898.2 - 2.3e-05 24.4 13.5 0.011 15.7 8.4 2.3 2 1 0 2 2 2 2 SIKE family Nsp1_C PF05064.13 EAU85898.2 - 0.013 15.3 5.7 0.019 14.8 0.7 2.9 2 1 0 3 3 3 0 Nsp1-like C-terminal region Kdo_hydroxy PF11004.8 EAU85898.2 - 0.03 13.6 0.5 0.044 13.0 0.5 1.4 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF3920 PF13058.6 EAU85898.2 - 0.062 13.5 0.2 0.097 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) NYD-SP28_assoc PF14775.6 EAU85898.2 - 0.49 10.5 12.2 1.6 8.9 0.8 3.2 3 1 0 3 3 3 0 Sperm tail C-terminal domain TACC_C PF05010.14 EAU85898.2 - 0.58 9.9 12.3 0.42 10.4 5.2 2.8 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Prominin PF05478.11 EAU85898.2 - 1.2 7.0 5.9 1.5 6.7 5.9 1.1 1 0 0 1 1 1 0 Prominin Cnn_1N PF07989.11 EAU85898.2 - 1.7 8.8 8.6 4.7 7.4 2.2 3.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 EAU85898.2 - 2.5 8.3 8.2 5.2 7.2 0.6 3.1 2 1 0 3 3 3 0 bZIP transcription factor Spore_III_AB PF09548.10 EAU85898.2 - 4.5 7.4 11.1 1.8 8.7 6.7 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Rootletin PF15035.6 EAU85898.2 - 5.7 6.9 15.4 0.45 10.5 5.2 2.9 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Wtap PF17098.5 EAU85898.2 - 6.3 6.7 13.4 1.2 9.0 1.3 3.0 2 1 1 3 3 3 0 WTAP/Mum2p family E2F_CC-MB PF16421.5 EAU85898.2 - 6.3 7.2 8.2 0.52 10.7 1.7 2.5 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain PH PF00169.29 EAU85899.2 - 0.0049 17.3 0.0 0.019 15.4 0.0 2.1 2 0 0 2 2 2 1 PH domain HA2 PF04408.23 EAU85900.2 - 3.5e-25 88.4 1.0 2.4e-24 85.7 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAU85900.2 - 1.3e-18 67.1 0.0 3.1e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAU85900.2 - 1.7e-13 50.9 0.2 3e-10 40.4 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU85900.2 - 1.3e-06 28.3 0.2 3.2e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU85900.2 - 2.7e-06 27.7 0.0 1.6e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EAU85900.2 - 0.0098 15.9 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAU85900.2 - 0.016 15.6 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAU85900.2 - 0.017 14.9 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAU85900.2 - 0.017 14.4 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EAU85900.2 - 0.043 13.2 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 EAU85900.2 - 0.12 12.8 0.1 0.12 12.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain SEN1_N PF12726.7 EAU85901.2 - 8.5e-155 516.9 0.2 1.2e-154 516.4 0.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EAU85901.2 - 4e-69 233.3 0.9 4e-69 233.3 0.9 2.4 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 EAU85901.2 - 2.3e-59 200.4 0.0 4.8e-59 199.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU85901.2 - 3e-11 43.4 0.8 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EAU85901.2 - 3.1e-11 43.8 0.1 9.4e-11 42.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU85901.2 - 0.00012 21.9 0.2 0.082 12.6 0.0 3.8 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EAU85901.2 - 0.00015 21.5 0.1 0.00015 21.5 0.1 3.0 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 EAU85901.2 - 0.0012 18.7 0.1 0.0047 16.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 EAU85901.2 - 0.0021 17.9 0.1 0.63 9.9 0.0 3.2 3 1 0 3 3 3 1 Helicase AAA_22 PF13401.6 EAU85901.2 - 0.0055 17.0 0.1 0.058 13.7 0.0 2.8 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 EAU85901.2 - 0.0095 16.4 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU85901.2 - 0.018 15.4 1.3 0.057 13.8 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 EAU85901.2 - 0.02 14.9 0.0 0.11 12.4 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 EAU85901.2 - 0.039 13.0 0.0 0.097 11.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EAU85901.2 - 0.08 12.5 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Translin PF01997.16 EAU85902.1 - 5.6e-48 163.6 0.0 6.5e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Translin family CBFD_NFYB_HMF PF00808.23 EAU85903.1 - 1.4e-05 25.3 0.0 2.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Apt1 PF10351.9 EAU85903.1 - 0.14 11.0 3.0 0.21 10.4 3.0 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Histone PF00125.24 EAU85903.1 - 3.7 7.9 0.0 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DIOX_N PF14226.6 EAU85906.2 - 3.9e-25 88.9 0.1 6.6e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAU85906.2 - 3e-08 34.0 0.0 6.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA_bind PF01588.20 EAU85907.1 - 5.9e-29 100.0 0.0 1.1e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 EAU85907.1 - 0.0005 20.2 0.0 0.0016 18.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU85907.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU85907.1 - 0.026 14.5 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EAU85907.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NARP1 PF12569.8 EAU85907.1 - 4.8 6.0 7.7 6.6 5.5 7.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_L6 PF00347.23 EAU85908.2 - 2.2e-21 76.3 0.1 1.8e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 PLDc PF00614.22 EAU85909.2 - 4e-14 52.1 0.5 1.1e-05 25.4 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EAU85909.2 - 8.4e-13 48.4 0.0 5.1e-07 29.6 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EAU85909.2 - 9.9e-09 35.2 0.0 4.1e-07 30.0 0.0 2.8 2 0 0 2 2 2 1 PX domain ThiF PF00899.21 EAU85910.2 - 9.6e-28 97.2 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF3895 PF13034.6 EAU85910.2 - 0.11 12.5 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) Fungal_trans PF04082.18 EAU85911.2 - 3.3e-21 75.5 0.0 5e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPR_2 PF13041.6 EAU85912.1 - 4.5e-07 30.0 0.0 0.011 15.9 0.1 3.5 2 1 1 3 3 3 3 PPR repeat family GRASP55_65 PF04495.14 EAU85913.2 - 2.4e-52 176.9 0.0 4.3e-43 146.9 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EAU85913.2 - 6.9e-05 22.6 0.1 0.00057 19.7 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 EAU85913.2 - 0.00012 22.3 0.0 0.079 13.3 0.0 2.4 2 0 0 2 2 2 2 PDZ domain RhgB_N PF09284.10 EAU85914.2 - 7.6e-42 143.6 4.5 5.1e-21 75.4 0.1 2.4 1 1 1 2 2 2 2 Rhamnogalacturonan lyase B, N-terminal fn3_3 PF14686.6 EAU85914.2 - 5.9e-19 67.6 3.6 8.3e-17 60.7 0.7 2.7 2 0 0 2 2 2 2 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 EAU85914.2 - 1.3e-15 57.6 0.2 8.7e-15 55.0 0.2 2.3 1 1 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 EAU85914.2 - 0.00011 22.5 1.6 0.00042 20.5 1.6 2.0 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain MATH PF00917.26 EAU85915.2 - 1.2e-05 25.4 0.0 2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 EAU85915.2 - 0.0049 17.1 0.0 2.3 8.5 0.0 3.1 3 0 0 3 3 3 2 BTB/POZ domain RRM_1 PF00076.22 EAU85916.2 - 6.2e-46 154.1 1.1 4.2e-17 61.7 0.0 5.2 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU85916.2 - 3.1e-11 43.0 0.0 0.025 14.5 0.0 3.9 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EAU85916.2 - 0.00092 19.0 0.1 2.9 7.7 0.0 3.3 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain TPR_19 PF14559.6 EAU85916.2 - 0.0011 19.4 0.2 0.019 15.5 0.0 3.1 4 0 0 4 4 2 1 Tetratricopeptide repeat Suf PF05843.14 EAU85916.2 - 0.0015 18.6 5.9 0.0015 18.6 5.9 2.7 2 2 0 2 2 2 1 Suppressor of forked protein (Suf) RRM_7 PF16367.5 EAU85916.2 - 0.0024 17.9 0.1 6 7.1 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 EAU85916.2 - 0.0038 17.2 3.6 1 9.4 0.1 4.7 5 0 0 5 5 5 1 RNA binding motif Nup35_RRM_2 PF14605.6 EAU85916.2 - 0.014 15.4 0.0 6.6 6.8 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif NRDE-2 PF08424.10 EAU85916.2 - 0.042 13.0 6.3 7.4 5.6 4.5 3.6 2 2 0 2 2 2 0 NRDE-2, necessary for RNA interference PET122 PF05476.11 EAU85916.2 - 0.15 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 PET122 TPR_14 PF13428.6 EAU85916.2 - 8.2 7.5 9.0 27 5.9 0.0 5.6 5 1 1 6 6 5 0 Tetratricopeptide repeat F-box-like PF12937.7 EAU85917.2 - 2.3e-12 46.6 0.3 1.1e-11 44.4 0.3 2.3 1 0 0 1 1 1 1 F-box-like adh_short_C2 PF13561.6 EAU85918.1 - 1.7e-40 139.1 0.2 4.6e-39 134.3 0.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU85918.1 - 4.2e-39 134.0 0.3 7.3e-39 133.3 0.0 1.6 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAU85918.1 - 9.4e-07 28.9 0.4 2.3e-06 27.6 0.4 1.6 1 0 0 1 1 1 1 KR domain SKN1 PF03935.15 EAU85919.2 - 1.3e-196 653.9 0.1 1.6e-196 653.6 0.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RasGEF PF00617.19 EAU85921.2 - 3.2e-58 196.9 0.3 7.5e-58 195.6 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAU85921.2 - 3e-19 69.2 0.2 8.5e-19 67.7 0.2 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EAU85921.2 - 1.7e-15 56.3 0.1 4.1e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU85921.2 - 2.6e-13 49.6 0.1 6.3e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU85921.2 - 1.8e-12 46.7 0.0 3.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EAU85921.2 - 6.9e-08 32.5 11.2 1.4e-06 28.3 7.0 2.6 2 0 0 2 2 2 2 WW domain DUF3439 PF11921.8 EAU85921.2 - 5.9 6.9 8.3 15 5.6 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dehydrin PF00257.19 EAU85922.2 - 0.15 12.6 13.2 0.35 11.4 13.2 1.7 1 0 0 1 1 1 0 Dehydrin CBFD_NFYB_HMF PF00808.23 EAU85923.2 - 9.6e-17 61.0 0.2 2.1e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU85923.2 - 2.5e-07 31.1 0.6 4.2e-07 30.4 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EAU85923.2 - 0.065 13.3 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CDC45 PF02724.14 EAU85923.2 - 0.89 7.8 4.7 0.99 7.6 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_33 PF10017.9 EAU85926.1 - 7.7e-78 261.7 0.0 1.2e-77 261.1 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EAU85926.1 - 7.1e-26 91.3 1.3 1.9e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EAU85926.1 - 1.3e-07 32.2 0.6 2.6e-07 31.2 0.6 1.5 1 0 0 1 1 1 1 DinB superfamily Choline_kinase PF01633.20 EAU85927.2 - 0.00049 19.7 0.0 0.00064 19.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EAU85927.2 - 0.0045 16.4 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU85927.2 - 0.033 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EAU85927.2 - 0.055 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SET PF00856.28 EAU85929.2 - 3.8e-06 27.4 0.0 1.4e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 SET domain DUF202 PF02656.15 EAU85930.2 - 2.6e-16 59.8 0.1 2.6e-16 59.8 0.1 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF202) F-box-like PF12937.7 EAU85932.2 - 1.5e-07 31.2 0.5 1.5e-07 31.2 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EAU85932.2 - 0.084 12.8 0.7 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 F-box F-box PF00646.33 EAU85932.2 - 0.49 10.3 6.7 0.23 11.4 2.3 2.5 2 1 0 2 2 2 0 F-box domain UAA PF08449.11 EAU85933.2 - 9.6e-61 205.6 6.8 1e-60 205.5 6.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EAU85933.2 - 2.3e-10 40.8 13.9 5.9e-08 33.0 3.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EAU85933.2 - 1.6e-05 24.1 1.4 2.2e-05 23.6 1.3 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EAU85933.2 - 0.00026 20.5 4.1 0.0017 17.7 4.1 2.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 EAU85933.2 - 0.00087 18.6 10.0 0.0044 16.3 2.8 2.0 2 0 0 2 2 2 2 Purine nucleobase transmembrane transport SLC35F PF06027.12 EAU85933.2 - 0.0016 18.0 0.4 0.0016 18.0 0.4 1.7 2 0 0 2 2 2 1 Solute carrier family 35 Methyltransf_11 PF08241.12 EAU85934.2 - 8.6e-09 35.9 0.1 1.5e-07 32.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU85934.2 - 3.9e-08 33.2 0.0 2.2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU85934.2 - 3e-07 31.1 0.3 0.0056 17.4 0.0 2.9 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EAU85934.2 - 3.3e-07 30.3 0.0 8e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU85934.2 - 1.1e-06 29.2 0.1 0.0001 23.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAU85934.2 - 5.8e-06 25.5 0.0 6e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EAU85934.2 - 0.0012 18.4 0.1 0.018 14.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 EAU85934.2 - 0.0014 18.4 0.0 0.0052 16.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EAU85934.2 - 0.011 15.0 0.0 0.13 11.6 0.0 2.3 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EAU85934.2 - 0.025 13.8 0.0 0.069 12.4 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EAU85934.2 - 0.066 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N6_Mtase PF02384.16 EAU85934.2 - 0.17 11.1 0.0 0.39 9.9 0.0 1.5 2 0 0 2 2 2 0 N-6 DNA Methylase RRM_1 PF00076.22 EAU85935.2 - 1.8e-07 30.9 0.0 3.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU85935.2 - 0.00019 21.2 0.2 0.0005 19.9 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EAU85935.2 - 0.00023 21.2 0.7 0.00056 19.9 0.0 2.0 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EAU85935.2 - 0.00038 20.4 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Inj_translocase PF16928.5 EAU85935.2 - 0.1 12.0 1.5 0.31 10.5 1.3 1.7 1 1 1 2 2 2 0 DNA/protein translocase of phage P22 injectosome LRR_4 PF12799.7 EAU85938.2 - 1.1e-15 57.5 24.7 0.00044 20.6 0.5 5.7 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EAU85938.2 - 6.1e-12 45.1 21.6 1.5e-05 24.7 3.0 4.9 3 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EAU85938.2 - 4.7e-10 39.2 6.8 1.5e-05 24.5 2.4 3.2 1 1 2 3 3 3 3 Leucine-rich repeat Homeobox_KN PF05920.11 EAU85939.2 - 5.9e-19 67.7 1.8 1e-18 67.0 0.1 2.4 2 0 0 2 2 2 1 Homeobox KN domain LRR_8 PF13855.6 EAU85939.2 - 8.7e-07 28.6 0.5 1.7e-06 27.7 0.5 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EAU85939.2 - 1.5e-06 28.4 5.9 0.00062 20.1 1.2 2.4 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) Homeodomain PF00046.29 EAU85939.2 - 4e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 Homeodomain LRR_9 PF14580.6 EAU85939.2 - 9.3e-05 22.0 0.2 0.035 13.6 0.3 2.2 2 0 0 2 2 2 2 Leucine-rich repeat Anillin_N PF16018.5 EAU85939.2 - 0.8 10.4 3.6 2.7 8.7 3.6 1.9 1 0 0 1 1 1 0 Anillin N-terminus LRR_1 PF00560.33 EAU85939.2 - 1.1 10.0 3.4 2.9 8.8 0.3 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat cobW PF02492.19 EAU85940.2 - 7.3e-27 94.1 0.0 8.8e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.13 EAU85940.2 - 0.0037 16.5 0.0 0.0055 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain MMR_HSR1 PF01926.23 EAU85940.2 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EAU85940.2 - 0.019 15.5 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAU85940.2 - 0.039 14.4 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EAU85940.2 - 0.049 14.1 0.0 0.072 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EAU85940.2 - 0.071 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EAU85940.2 - 0.082 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 EAU85940.2 - 0.084 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 EAU85940.2 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 EAU85940.2 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.12 EAU85940.2 - 0.16 11.8 0.1 0.37 10.7 0.1 1.5 1 1 0 1 1 1 0 NACHT domain Iwr1 PF08574.10 EAU85941.1 - 2.3e-13 51.0 13.6 2.3e-13 51.0 13.6 2.3 3 0 0 3 3 3 1 Transcription factor Iwr1 HCO3_cotransp PF00955.21 EAU85942.2 - 1.2e-75 255.3 5.3 2.8e-34 118.9 2.2 3.1 2 1 1 3 3 3 3 HCO3- transporter family Ferric_reduct PF01794.19 EAU85942.2 - 1 9.5 11.0 0.047 13.8 4.1 2.3 3 0 0 3 3 3 0 Ferric reductase like transmembrane component Hydrolase_4 PF12146.8 EAU85943.2 - 8.3e-11 41.6 0.8 3.4e-10 39.6 0.8 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU85943.2 - 3.2e-10 41.0 0.6 4.7e-10 40.4 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU85943.2 - 4.3e-09 36.4 0.5 7.2e-08 32.4 0.2 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EAU85943.2 - 1.7e-08 34.6 0.4 3.2e-08 33.7 0.4 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 EAU85943.2 - 0.00076 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.18 EAU85943.2 - 0.019 14.6 0.1 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 EAU85943.2 - 0.17 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF126 PF01989.16 EAU85943.2 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Aconitase X swivel domain PHY PF00360.20 EAU85944.2 - 1.3e-21 76.8 0.0 2.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EAU85944.2 - 6.6e-21 74.9 0.2 1.3e-20 74.0 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAU85944.2 - 8.4e-20 71.0 0.2 3e-19 69.3 0.1 2.0 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EAU85944.2 - 1.6e-11 44.1 1.6 3.3e-11 43.0 1.6 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EAU85944.2 - 0.00017 22.2 0.0 0.00065 20.3 0.0 2.0 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 EAU85944.2 - 0.00066 20.3 0.0 0.0027 18.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold CwfJ_C_2 PF04676.14 EAU85946.1 - 4.7e-33 114.0 0.0 4.7e-33 114.0 0.0 3.4 3 1 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EAU85946.1 - 6.3e-32 110.0 0.1 9.7e-32 109.4 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 GTP_EFTU PF00009.27 EAU85947.2 - 8.1e-59 198.4 0.1 1.3e-58 197.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAU85947.2 - 1.4e-15 57.0 0.0 4.3e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAU85947.2 - 5.6e-09 36.3 0.0 1.5e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAU85947.2 - 3.3e-08 33.5 0.0 7.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EAU85947.2 - 6.6e-05 23.0 0.1 0.00015 21.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAU85947.2 - 0.054 12.9 0.1 0.19 11.2 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_IV PF03764.18 EAU85947.2 - 0.07 12.9 0.0 0.41 10.4 0.0 2.3 1 1 1 2 2 2 0 Elongation factor G, domain IV MMS1_N PF10433.9 EAU85948.2 - 4e-58 197.2 0.0 6.1e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EAU85948.2 - 5.2e-36 124.6 0.0 1.9e-35 122.7 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region Na_Ca_ex PF01699.24 EAU85949.2 - 2.6e-18 66.4 42.3 1.2e-12 48.1 10.4 3.4 3 1 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 EAU85949.2 - 3.8e-14 53.1 31.1 6.9e-12 45.9 12.9 4.0 2 0 0 2 2 2 2 Inner membrane component domain FAM209 PF15206.6 EAU85949.2 - 0.17 11.7 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 FAM209 family TMV_coat PF00721.21 EAU85950.1 - 0.023 14.5 0.3 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Virus coat protein (TMV like) Tmemb_cc2 PF10267.9 EAU85950.1 - 1.3 8.1 12.3 0.01 15.1 1.9 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Helicase_C_2 PF13307.6 EAU85951.2 - 3.3e-52 177.1 0.0 1.3e-50 171.9 0.0 3.0 3 1 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 EAU85951.2 - 1.1e-36 126.2 1.0 2.9e-23 82.4 0.0 3.5 1 1 1 2 2 2 2 DEAD_2 ResIII PF04851.15 EAU85951.2 - 7.1e-05 22.9 0.0 0.02 14.9 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EAU85951.2 - 0.0003 20.3 0.0 0.035 13.5 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 EAU85951.2 - 0.0049 16.6 1.1 0.05 13.4 1.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.6 EAU85951.2 - 0.014 15.0 0.7 0.041 13.5 0.7 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU85951.2 - 0.028 14.7 0.1 5.8 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF3510 PF12022.8 EAU85951.2 - 0.99 9.8 6.6 3.6 8.0 1.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF4553 PF15090.6 EAU85951.2 - 1.5 7.7 8.7 2.5 7.0 6.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4553) adh_short PF00106.25 EAU85953.2 - 1.2e-45 155.4 0.0 1.6e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU85953.2 - 3.2e-41 141.4 0.0 4e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU85953.2 - 5.1e-06 26.5 0.0 8.6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU85953.2 - 0.00058 19.4 0.0 0.00097 18.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EAU85953.2 - 0.11 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 EAU85953.2 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ACR_tran PF00873.19 EAU85954.2 - 0.083 10.5 0.1 0.13 9.8 0.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF5353 PF17304.2 EAU85954.2 - 0.15 11.8 0.3 0.33 10.7 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5353) HA2 PF04408.23 EAU85955.2 - 1.2e-22 80.3 0.0 1.2e-22 80.3 0.0 3.9 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAU85955.2 - 3.4e-20 72.2 0.5 8.2e-20 71.0 0.5 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAU85955.2 - 3.1e-15 56.5 0.0 9.2e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU85955.2 - 5.7e-08 32.7 0.6 8.8e-07 28.9 0.0 3.1 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EAU85955.2 - 6.9e-05 22.7 0.0 6.9e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU85955.2 - 0.00016 21.9 0.3 0.0011 19.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU85955.2 - 0.00081 19.8 0.7 0.0029 17.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EAU85955.2 - 0.0038 16.3 0.0 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 EAU85955.2 - 3 7.8 8.3 3.5 7.6 0.2 3.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit HpcH_HpaI PF03328.14 EAU85956.2 - 1.8e-44 151.5 0.0 3.3e-44 150.6 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EAU85956.2 - 5.9e-12 45.4 0.0 7.8e-09 35.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold dsrm PF00035.26 EAU85958.1 - 3.6e-10 40.4 0.1 7.4e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EAU85958.1 - 2.3e-08 34.3 0.0 3.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EAU85958.1 - 0.00037 21.1 0.0 0.00075 20.1 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain Glycos_transf_3 PF00591.21 EAU85959.2 - 4e-75 252.7 0.0 5.2e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EAU85959.2 - 1.1e-07 31.6 0.0 2.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain HEAT_2 PF13646.6 EAU85962.1 - 2.4e-34 117.6 2.8 5.5e-15 55.5 0.2 4.3 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 EAU85962.1 - 4.8e-25 85.7 0.6 0.0017 18.8 0.0 7.5 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EAU85962.1 - 3.5e-13 48.6 0.7 0.018 15.3 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EAU85962.1 - 4.8e-08 33.3 1.0 1.4 9.5 0.1 5.6 5 2 1 6 6 6 3 HEAT-like repeat Arm PF00514.23 EAU85962.1 - 4.3e-07 29.8 0.1 0.0038 17.2 0.0 3.7 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EAU85962.1 - 0.0072 16.4 0.0 3.7 7.6 0.0 3.2 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 LppA PF16708.5 EAU85962.1 - 0.058 13.3 0.9 2.4 8.1 0.2 2.3 2 1 0 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium RL10P_insert PF17777.1 EAU85963.2 - 1.9e-21 75.9 0.0 3.4e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EAU85963.2 - 7e-17 61.4 0.0 9.5e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_S9 PF00326.21 EAU85964.1 - 1.2e-42 145.9 0.0 2e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 EAU85964.1 - 0.055 12.6 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) DUF4936 PF16290.5 EAU85965.2 - 0.075 13.7 1.4 8.6 7.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) zf-CCHC_3 PF13917.6 EAU85966.2 - 8.3e-20 70.5 1.6 1.8e-19 69.4 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle IMUP PF15761.5 EAU85966.2 - 0.0034 18.0 13.7 0.0067 17.1 13.7 1.5 1 0 0 1 1 1 1 Immortalisation up-regulated protein AF-4 PF05110.13 EAU85966.2 - 0.0066 14.6 12.4 0.0074 14.5 12.4 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SR-25 PF10500.9 EAU85966.2 - 0.0072 16.0 16.5 0.01 15.5 16.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.12 EAU85966.2 - 0.018 13.7 10.8 0.021 13.5 10.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM60A PF15396.6 EAU85966.2 - 0.026 14.5 5.2 0.035 14.1 5.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RAP1 PF07218.11 EAU85966.2 - 0.085 11.1 5.7 0.1 10.9 5.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Atrophin-1 PF03154.15 EAU85966.2 - 0.17 10.1 10.6 0.19 9.9 10.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family SPATIAL PF15256.6 EAU85966.2 - 0.4 11.0 3.0 0.53 10.6 3.0 1.2 1 0 0 1 1 1 0 SPATIAL Afi1 PF07792.12 EAU85966.2 - 0.48 10.9 4.1 0.58 10.6 3.3 1.5 2 0 0 2 2 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Apt1 PF10351.9 EAU85966.2 - 0.64 8.8 6.4 0.69 8.7 6.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EAU85966.2 - 0.75 8.5 4.7 0.88 8.3 4.7 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EAU85966.2 - 0.87 7.6 2.0 0.91 7.6 2.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF755 PF05501.11 EAU85966.2 - 0.88 9.9 20.9 1.8 8.9 20.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Phage_Gp23 PF10669.9 EAU85966.2 - 1.1 9.6 7.3 27 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) CDC45 PF02724.14 EAU85966.2 - 1.2 7.3 6.2 1.3 7.2 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EAU85966.2 - 1.6 6.7 6.8 2 6.4 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 EAU85966.2 - 2.8 6.9 12.0 3.4 6.6 12.0 1.1 1 0 0 1 1 1 0 Paf1 EBP50_C PF09007.11 EAU85966.2 - 3.7 8.5 12.7 2.3 9.2 11.0 1.5 1 1 1 2 2 2 0 EBP50, C-terminal UPF0560 PF10577.9 EAU85966.2 - 3.9 5.8 8.5 4.7 5.6 8.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ATP-synt_C PF00137.21 EAU85967.2 - 6.1e-32 109.8 31.5 7e-20 71.1 11.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Zip PF02535.22 EAU85968.2 - 1.5e-30 106.6 7.9 2.5e-30 105.9 7.8 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter HPP PF04982.13 EAU85968.2 - 3.7 7.8 7.5 0.7 10.1 0.7 2.4 2 1 0 2 2 2 0 HPP family DUF1772 PF08592.11 EAU85968.2 - 4.4 7.6 6.7 4.9 7.5 3.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) E1_dh PF00676.20 EAU85969.2 - 1.1e-84 284.0 0.0 1.3e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Herpes_gE PF02480.16 EAU85970.2 - 0.005 15.6 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 EAU85970.2 - 0.064 14.1 0.0 0.14 13.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4051 PF13260.6 EAU85970.2 - 0.3 10.9 0.6 0.54 10.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) SNF5 PF04855.12 EAU85972.2 - 4.2e-74 249.3 0.0 1.7e-73 247.3 0.0 1.8 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 F-box-like PF12937.7 EAU85973.1 - 5.7e-05 22.9 0.5 0.00094 19.0 0.0 3.1 4 0 0 4 4 4 1 F-box-like LRR_9 PF14580.6 EAU85973.1 - 0.0095 15.5 3.0 0.36 10.3 0.1 3.2 2 1 1 3 3 3 2 Leucine-rich repeat Waikav_capsid_1 PF12264.8 EAU85973.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Waikavirus capsid protein 1 zf-C2H2 PF00096.26 EAU85975.1 - 2e-09 37.4 10.1 8e-05 22.9 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU85975.1 - 5.2e-07 29.8 14.5 3.9e-06 27.0 2.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU85975.1 - 1.9e-05 25.1 8.3 0.037 14.9 1.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger WD40 PF00400.32 EAU85977.2 - 3.6e-06 27.6 2.9 2.4 9.2 0.2 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4611 PF15387.6 EAU85977.2 - 0.2 11.9 1.4 0.45 10.7 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Q_salvage PF10343.9 EAU85978.1 - 1e-57 195.9 0.0 1.1e-57 195.7 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family BcsB PF03170.13 EAU85980.2 - 0.018 13.4 0.0 0.035 12.5 0.0 1.4 1 1 0 1 1 1 0 Bacterial cellulose synthase subunit Arrestin_N PF00339.29 EAU85980.2 - 0.08 13.0 0.0 0.37 10.8 0.0 1.9 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain TPR_MLP1_2 PF07926.12 EAU85981.2 - 3.1e-29 101.7 24.1 3.1e-29 101.7 24.1 17.6 6 4 8 16 16 16 5 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 EAU85981.2 - 9.1e-05 21.8 42.2 9.1e-05 21.8 42.2 10.3 4 3 2 7 7 7 1 Myosin-like coiled-coil protein FPP PF05911.11 EAU85981.2 - 9.3e-05 20.8 11.2 9.3e-05 20.8 11.2 10.1 2 2 5 7 7 7 3 Filament-like plant protein, long coiled-coil MtrB PF05440.12 EAU85981.2 - 0.31 11.5 0.9 27 5.3 0.0 4.5 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B FANCI_S1-cap PF14674.6 EAU85981.2 - 9.9 6.3 10.4 3.8 7.7 3.2 4.4 3 0 0 3 3 3 0 FANCI solenoid 1 cap Ribosomal_S10 PF00338.22 EAU85982.1 - 2.2e-28 98.3 0.4 2.6e-28 98.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e UPF0126 PF03458.13 EAU85983.2 - 0.017 15.0 0.1 5.4 7.0 0.0 2.7 2 0 0 2 2 2 0 UPF0126 domain AMP-binding PF00501.28 EAU85986.2 - 1e-76 258.2 0.0 1.7e-76 257.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU85986.2 - 0.0042 18.0 0.0 0.012 16.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cation_ATPase_C PF00689.21 EAU85986.2 - 0.0069 16.1 4.5 0.0069 16.1 4.5 1.7 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF4396 PF14342.6 EAU85986.2 - 0.039 14.3 2.1 0.086 13.2 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) Cytochrom_B561 PF03188.16 EAU85986.2 - 0.13 12.4 2.6 0.25 11.5 0.2 2.1 1 1 0 2 2 2 0 Eukaryotic cytochrome b561 PhoLip_ATPase_C PF16212.5 EAU85986.2 - 0.41 10.3 12.3 0.015 15.1 4.6 2.1 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Kinocilin PF15033.6 EAU85986.2 - 0.54 9.9 3.4 14 5.4 0.2 2.9 1 1 1 2 2 2 0 Kinocilin protein AAA_23 PF13476.6 EAU85987.1 - 1e-32 114.3 0.0 1e-32 114.3 0.0 8.8 1 1 2 3 3 1 1 AAA domain AAA_15 PF13175.6 EAU85987.1 - 1.3e-11 44.8 78.4 5e-11 42.9 1.6 5.6 1 1 2 4 4 3 3 AAA ATPase domain AAA_21 PF13304.6 EAU85987.1 - 3.7e-10 40.1 0.0 5.7e-06 26.4 0.1 4.7 4 1 1 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU85987.1 - 7.1e-10 38.7 0.1 7.1e-10 38.7 0.1 3.7 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EAU85987.1 - 1.4e-06 28.5 0.0 4.5e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Lebercilin PF15619.6 EAU85987.1 - 0.00042 20.0 10.7 0.00042 20.0 10.7 9.8 2 2 6 8 8 6 3 Ciliary protein causing Leber congenital amaurosis disease AAA_29 PF13555.6 EAU85987.1 - 0.00096 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EAU85987.1 - 0.0025 18.3 0.0 0.0025 18.3 0.0 7.0 4 3 0 4 4 2 1 ABC transporter AAA_13 PF13166.6 EAU85987.1 - 0.003 16.3 0.0 0.003 16.3 0.0 7.3 2 1 3 6 6 5 3 AAA domain ABC_tran_CTD PF16326.5 EAU85987.1 - 0.015 15.6 1.3 0.015 15.6 1.3 12.0 5 4 8 14 14 14 0 ABC transporter C-terminal domain Roc PF08477.13 EAU85987.1 - 0.062 13.5 1.3 0.19 11.9 0.0 2.6 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EAU85987.1 - 0.25 11.7 0.0 0.25 11.7 0.0 5.2 4 2 0 4 4 2 0 AAA ATPase domain GTP_EFTU PF00009.27 EAU85987.1 - 0.38 10.3 0.0 0.38 10.3 0.0 4.4 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.6 EAU85987.1 - 0.43 10.9 7.5 5.9 7.2 0.1 4.3 3 1 0 3 3 3 0 AAA domain Sec3_C_2 PF15278.6 EAU85987.1 - 0.78 10.1 9.0 4 7.9 0.4 4.8 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Mce4_CUP1 PF11887.8 EAU85987.1 - 4.4 6.7 14.1 21 4.5 3.4 3.9 2 2 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative MRP-L47 PF06984.13 EAU85989.2 - 1.7e-12 47.3 0.1 5.1e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Draxin PF15550.6 EAU85989.2 - 0.15 11.9 9.9 0.34 10.7 10.0 1.4 1 1 1 2 2 2 0 Draxin MAT1 PF06391.13 EAU85989.2 - 0.6 9.9 7.3 1.2 9.0 7.3 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 F-box-like PF12937.7 EAU85991.2 - 0.13 12.2 0.1 0.41 10.6 0.1 1.9 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 EAU85992.2 - 9e-29 100.5 35.4 4.2e-27 95.0 33.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EAU85992.2 - 0.11 12.3 7.1 6 6.6 0.1 2.7 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Glyco_hydro_71 PF03659.14 EAU85993.2 - 5.1e-111 371.1 0.0 7.8e-111 370.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CRAL_TRIO PF00650.20 EAU85993.2 - 1.1e-25 90.3 0.0 1.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAU85993.2 - 9.6e-05 22.5 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain vATP-synt_AC39 PF01992.16 EAU85994.1 - 1.7e-116 389.4 2.0 1.9e-116 389.3 2.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 EAU85994.1 - 0.036 14.0 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain DER1 PF04511.15 EAU85996.2 - 2.8e-48 164.4 3.1 3.6e-48 164.0 3.1 1.1 1 0 0 1 1 1 1 Der1-like family SAM_2 PF07647.17 EAU85997.2 - 2.3e-09 37.2 0.1 1.2e-08 35.0 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EAU85997.2 - 0.00032 21.1 0.0 0.0007 20.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1281 PF06924.11 EAU85997.2 - 0.011 15.2 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4508 PF14969.6 EAU85997.2 - 0.07 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) IGR PF09597.10 EAU85997.2 - 0.13 12.4 0.1 0.39 10.9 0.1 1.8 1 0 0 1 1 1 0 IGR protein motif His_Phos_2 PF00328.22 EAU85998.1 - 1.3e-43 149.8 0.0 1.6e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3752 PF12572.8 EAU85999.2 - 6e-41 140.5 8.9 6e-41 140.5 8.9 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) CRAL_TRIO PF00650.20 EAU86000.2 - 1.4e-23 83.4 0.0 2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAU86000.2 - 2.5e-07 30.7 0.0 6.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Motile_Sperm PF00635.26 EAU86001.2 - 1.7e-26 92.2 0.1 4e-26 91.0 0.1 1.7 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 EAU86001.2 - 0.0074 16.5 0.0 0.026 14.7 0.0 2.0 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 EAU86001.2 - 0.013 15.7 0.1 0.029 14.6 0.1 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase TolA_bind_tri PF16331.5 EAU86001.2 - 0.33 11.1 5.7 0.82 9.8 5.7 1.6 1 1 0 1 1 1 0 TolA binding protein trimerisation DivIC PF04977.15 EAU86001.2 - 0.92 9.3 4.5 2.1 8.2 4.5 1.5 1 0 0 1 1 1 0 Septum formation initiator ABC_membrane PF00664.23 EAU86002.1 - 4.3e-105 351.3 26.3 1.3e-53 182.4 14.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAU86002.1 - 1.9e-70 235.7 0.1 5.3e-34 117.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAU86002.1 - 3.2e-15 56.2 2.8 3.6e-05 23.3 0.4 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU86002.1 - 6.8e-08 32.1 0.9 0.0097 15.6 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EAU86002.1 - 8.9e-08 31.3 0.3 0.0012 17.8 0.0 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EAU86002.1 - 5.5e-07 30.1 2.9 0.0033 17.8 0.1 3.2 2 1 1 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 EAU86002.1 - 1.7e-06 28.0 0.7 0.021 14.6 0.0 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EAU86002.1 - 2.3e-06 27.6 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EAU86002.1 - 3e-06 27.6 1.0 0.034 14.4 0.1 3.6 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 EAU86002.1 - 8.6e-06 25.2 0.0 0.018 14.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EAU86002.1 - 1.9e-05 24.7 0.0 0.11 12.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAU86002.1 - 5.1e-05 22.6 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 EAU86002.1 - 0.00021 21.1 0.5 1.2 8.8 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EAU86002.1 - 0.00022 21.8 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EAU86002.1 - 0.00073 20.1 0.0 0.6 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EAU86002.1 - 0.0025 17.7 0.1 3.5 7.5 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_33 PF13671.6 EAU86002.1 - 0.0034 17.5 0.0 3.6 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAU86002.1 - 0.0041 16.7 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 EAU86002.1 - 0.0042 17.1 0.0 5.8 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EAU86002.1 - 0.008 15.4 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PRK PF00485.18 EAU86002.1 - 0.012 15.4 0.1 0.91 9.2 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 EAU86002.1 - 0.012 14.9 0.1 4 6.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 EAU86002.1 - 0.015 15.4 1.9 4.3 7.4 0.3 3.2 4 0 0 4 4 3 0 Helicase HerA, central domain AAA_28 PF13521.6 EAU86002.1 - 0.018 15.3 0.1 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EAU86002.1 - 0.02 15.1 3.6 4.9 7.5 0.5 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EAU86002.1 - 0.029 13.9 3.5 2.3 7.8 0.5 3.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EAU86002.1 - 0.03 14.4 0.0 8.9 6.4 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EAU86002.1 - 0.034 13.9 0.0 7.6 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EAU86002.1 - 0.052 14.0 0.5 21 5.6 0.0 3.4 4 0 0 4 4 2 0 AAA domain NB-ARC PF00931.22 EAU86002.1 - 0.057 12.6 0.1 5.8 6.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.6 EAU86002.1 - 0.06 12.3 0.0 0.53 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) ATP_bind_1 PF03029.17 EAU86002.1 - 0.092 12.5 0.1 6.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 EAU86002.1 - 0.1 13.0 0.0 12 6.3 0.0 3.2 3 0 0 3 3 2 0 RNA helicase Pkinase PF00069.25 EAU86003.1 - 1.6e-73 247.4 0.0 2e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86003.1 - 2.8e-32 112.0 0.0 4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EAU86003.1 - 8.1e-10 39.2 2.9 2.2e-09 37.9 2.9 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EAU86003.1 - 1.6e-07 30.6 0.1 2.7e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EAU86003.1 - 4.5e-05 22.9 0.0 0.00036 20.0 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EAU86003.1 - 0.0073 15.7 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAU86003.1 - 0.014 15.0 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAU86003.1 - 0.063 13.2 0.3 0.19 11.6 0.2 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family AFP PF02420.15 EAU86005.2 - 0.88 10.1 5.5 0.19 12.1 1.2 2.2 2 0 0 2 2 2 0 Insect antifreeze protein repeat Nop16 PF09420.10 EAU86007.1 - 0.048 13.7 0.7 0.12 12.4 0.7 1.6 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Pkinase PF00069.25 EAU86010.2 - 1.1e-54 185.6 0.0 1.6e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86010.2 - 4e-25 88.6 0.0 1.9e-24 86.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EAU86010.2 - 0.0015 18.2 2.3 0.0023 17.5 0.1 2.3 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 EAU86010.2 - 0.0015 17.9 0.1 0.0079 15.6 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EAU86010.2 - 0.0024 17.2 0.1 0.0043 16.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAU86010.2 - 0.0027 17.4 0.0 0.75 9.4 0.0 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAU86010.2 - 0.18 10.5 0.1 0.43 9.3 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase F-box-like PF12937.7 EAU86011.2 - 2.2e-09 37.1 0.5 9.9e-07 28.6 0.4 2.6 2 0 0 2 2 2 2 F-box-like zf-CCCH PF00642.24 EAU86012.1 - 1.5e-11 43.9 20.2 9.6e-06 25.4 1.0 3.5 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAU86012.1 - 9.1e-10 38.3 26.5 0.00014 21.8 2.0 4.2 3 1 0 3 3 3 3 Zinc finger domain Torus PF16131.5 EAU86012.1 - 1.1e-05 26.1 12.4 0.087 13.5 2.6 3.4 2 1 1 3 3 3 3 Torus domain zf-CCCH_4 PF18044.1 EAU86012.1 - 1.4e-05 24.8 22.9 0.00057 19.6 0.9 4.1 3 1 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EAU86012.1 - 0.00012 22.4 19.1 0.0055 17.1 1.6 3.6 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EAU86012.1 - 0.038 14.2 13.1 0.16 12.2 0.2 3.1 2 1 0 2 2 2 0 Zinc-finger containing family Heme_oxygenase PF01126.20 EAU86014.1 - 2.2e-39 135.4 0.0 3.7e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Heme oxygenase NUP PF06516.11 EAU86014.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Asp PF00026.23 EAU86015.1 - 9e-24 84.4 0.7 3.9e-22 79.1 0.7 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 EAU86015.1 - 0.0049 17.4 0.0 17 6.0 0.0 3.5 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EAU86015.1 - 0.011 16.4 0.2 0.47 11.1 0.0 2.9 3 0 0 3 3 3 0 Aspartyl protease Asp PF00026.23 EAU86016.1 - 4.1e-20 72.4 0.0 2.6e-05 23.8 0.3 3.2 2 1 1 3 3 3 3 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EAU86016.1 - 0.0028 18.3 0.1 0.022 15.4 0.1 2.6 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 EAU86016.1 - 0.023 14.9 0.7 0.55 10.4 0.1 2.4 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EAU86016.1 - 0.061 13.9 0.0 0.31 11.6 0.0 2.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease SKG6 PF08693.10 EAU86016.1 - 0.24 10.8 2.3 0.51 9.8 2.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DNA_pol_B_exo1 PF03104.19 EAU86017.1 - 5.4e-36 124.4 0.0 7.2e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 EAU86017.1 - 0.0037 17.0 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_exo1 PF03104.19 EAU86018.2 - 3.5e-40 138.2 0.0 4.5e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 EAU86018.2 - 0.04 13.6 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF5326 PF17260.2 EAU86020.1 - 0.25 11.5 3.0 0.96 9.6 0.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Dynactin_p62 PF05502.13 EAU86021.1 - 6.3e-41 140.6 0.0 1.8e-26 93.0 0.0 2.1 2 0 0 2 2 2 2 Dynactin p62 family Aminotran_1_2 PF00155.21 EAU86022.1 - 2.9e-28 99.1 0.0 3.5e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EAU86022.1 - 5.7e-09 35.3 0.0 8.6e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EAU86022.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_15 PF00723.21 EAU86023.1 - 1.7e-89 300.7 0.0 2e-89 300.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EAU86023.1 - 2.4e-26 91.5 0.2 5.3e-26 90.4 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain Ysc84 PF04366.12 EAU86024.1 - 4.9e-45 152.4 0.1 7.4e-45 151.8 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator Sec7 PF01369.20 EAU86024.1 - 0.0037 17.0 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Phosphodiest PF01663.22 EAU86025.1 - 2.7e-83 280.5 0.7 3.3e-83 280.2 0.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EAU86025.1 - 0.027 13.9 0.1 6.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Sulfatase Gelsolin PF00626.22 EAU86027.2 - 1.3e-27 95.5 0.0 1.1e-14 54.1 0.0 3.5 3 0 0 3 3 3 3 Gelsolin repeat F-box-like PF12937.7 EAU86028.1 - 2.6e-06 27.2 0.0 5.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86028.1 - 6e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain Spt5_N PF11942.8 EAU86029.1 - 0.6 11.1 10.1 3.5 8.7 3.6 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF2681 PF10883.8 EAU86029.1 - 0.81 10.1 6.0 1.2 9.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DJ-1_PfpI PF01965.24 EAU86030.2 - 2.6e-12 46.9 0.1 9.1e-12 45.1 0.1 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EAU86030.2 - 8.2e-08 32.2 0.0 2.4e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 ThiJ/PfpI family-like Porin_3 PF01459.22 EAU86031.2 - 1.3e-73 247.8 1.7 1.5e-73 247.6 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin mRNA_triPase PF02940.15 EAU86032.1 - 3.8e-51 173.9 0.0 4.5e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain GCFC PF07842.12 EAU86033.2 - 0.11 12.1 0.0 1.3 8.5 0.0 2.1 1 1 0 2 2 2 0 GC-rich sequence DNA-binding factor-like protein STELLO PF03385.17 EAU86033.2 - 0.18 10.6 0.2 0.29 9.9 0.2 1.2 1 0 0 1 1 1 0 STELLO glycosyltransferases Rad60-SLD PF11976.8 EAU86034.1 - 3.9e-11 42.6 0.0 1.7e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAU86034.1 - 0.00015 21.4 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family SPT6_acidic PF14632.6 EAU86034.1 - 0.18 12.4 7.7 0.04 14.5 2.5 2.7 2 1 0 2 2 2 0 Acidic N-terminal SPT6 AidB_N PF18158.1 EAU86035.1 - 3.1e-27 95.4 0.0 5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EAU86035.1 - 1.4e-19 70.7 1.1 2.9e-19 69.8 1.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAU86035.1 - 8.9e-11 41.9 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAU86035.1 - 6.7e-08 32.9 0.1 1.2e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EAU86035.1 - 0.019 15.6 0.0 0.053 14.2 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain 4HBT PF03061.22 EAU86036.1 - 4.8e-12 46.1 0.3 6.8e-12 45.6 0.3 1.2 1 0 0 1 1 1 1 Thioesterase superfamily ParA PF10609.9 EAU86037.2 - 2.8e-64 216.9 0.3 1.1e-41 142.9 0.0 2.1 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAU86037.2 - 4.1e-10 39.8 0.0 2.1e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EAU86037.2 - 1e-08 35.3 0.3 2.7e-05 24.2 0.1 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EAU86037.2 - 0.001 18.4 0.2 0.0027 17.0 0.1 1.6 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 EAU86037.2 - 0.0016 18.0 0.9 0.0049 16.5 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EAU86037.2 - 0.0023 17.8 1.1 0.0058 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EAU86037.2 - 0.0031 16.7 3.2 0.033 13.4 0.5 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase Alg6_Alg8 PF03155.15 EAU86038.2 - 2.9e-137 458.6 16.2 3.7e-137 458.2 16.2 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family MRP-L20 PF12824.7 EAU86039.1 - 1.6e-34 119.5 8.2 3.1e-34 118.5 8.2 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Malic_M PF03949.15 EAU86040.2 - 5.4e-93 311.0 0.0 7.4e-93 310.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EAU86040.2 - 3.9e-65 219.1 0.0 7.6e-65 218.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain dCMP_cyt_deam_1 PF00383.23 EAU86041.2 - 5.9e-08 32.5 0.0 1.2e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SET PF00856.28 EAU86041.2 - 1.2e-07 32.3 0.0 2.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 SET domain MafB19-deam PF14437.6 EAU86041.2 - 4.9e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Glycos_transf_4 PF00953.21 EAU86042.2 - 5.8e-29 101.1 7.7 5.8e-29 101.1 7.7 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 ICL PF00463.21 EAU86043.1 - 1.1e-261 869.0 0.4 1.2e-261 868.8 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EAU86043.1 - 2.7e-09 36.8 0.3 6.3e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.18 EAU86043.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain F-actin_cap_A PF01267.17 EAU86044.1 - 7.7e-107 356.7 0.0 8.7e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PROCN PF08083.11 EAU86045.1 - 2.8e-232 770.6 10.4 5.5e-232 769.7 9.5 1.9 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EAU86045.1 - 7.2e-127 421.7 0.6 1.8e-126 420.4 0.6 1.7 2 0 0 2 2 2 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EAU86045.1 - 1.6e-87 291.4 2.1 1.6e-87 291.4 2.1 2.4 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EAU86045.1 - 6.5e-86 285.9 2.9 6.5e-86 285.9 2.9 2.7 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EAU86045.1 - 3.1e-73 244.2 0.1 6.1e-73 243.2 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EAU86045.1 - 1.5e-46 156.6 0.3 3.3e-46 155.5 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EAU86045.1 - 6e-42 142.4 0.0 1.3e-41 141.4 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 EAU86045.1 - 0.00098 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Corona_5a PF06336.11 EAU86045.1 - 0.075 13.0 0.1 0.28 11.2 0.1 2.0 1 0 0 1 1 1 0 Coronavirus 5a protein DUF1353 PF07087.11 EAU86045.1 - 0.12 12.1 0.2 0.69 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) DAHP_synth_1 PF00793.20 EAU86046.2 - 1.5e-97 325.7 0.0 1.9e-97 325.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.15 EAU86047.1 - 6.5e-19 67.3 7.3 8.7e-19 66.9 7.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tam41_Mmp37 PF09139.11 EAU86047.1 - 0.079 12.4 0.1 0.079 12.4 0.1 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Band_7 PF01145.25 EAU86052.2 - 9.2e-19 68.1 0.2 1.3e-18 67.6 0.2 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PQ-loop PF04193.14 EAU86053.2 - 5.4e-34 115.8 8.9 1.8e-18 66.0 2.7 2.6 2 0 0 2 2 2 2 PQ loop repeat F-box-like PF12937.7 EAU86054.1 - 4.8e-10 39.2 1.3 1e-09 38.1 0.0 2.4 3 0 0 3 3 3 1 F-box-like G-patch PF01585.23 EAU86055.2 - 3.5e-06 26.8 0.1 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 2 G-patch domain Pantoate_transf PF02548.15 EAU86056.1 - 2.9e-102 341.5 0.4 3.5e-102 341.2 0.4 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EAU86056.1 - 0.0018 17.8 0.2 0.0081 15.6 0.1 1.9 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase TPR_2 PF07719.17 EAU86058.2 - 1.8e-11 43.2 0.5 0.00063 19.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAU86058.2 - 1.8e-07 30.7 1.0 0.0065 16.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 EAU86058.2 - 6.4e-07 29.2 0.3 1.5e-06 28.0 0.3 1.6 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.6 EAU86058.2 - 1.8e-06 28.2 0.2 0.005 17.1 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU86058.2 - 9.8e-06 25.4 0.7 0.047 13.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAU86058.2 - 3.9e-05 24.1 0.0 0.014 15.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU86058.2 - 4.5e-05 23.9 0.4 0.16 12.9 0.4 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU86058.2 - 0.00015 22.4 0.1 0.067 13.9 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU86058.2 - 0.0098 16.2 0.3 0.17 12.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EAU86058.2 - 0.012 15.6 0.4 0.024 14.6 0.4 1.5 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_11 PF13414.6 EAU86058.2 - 0.067 12.9 0.0 16 5.2 0.1 2.4 2 0 0 2 2 2 0 TPR repeat TPR_9 PF13371.6 EAU86058.2 - 0.091 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAU86058.2 - 0.099 12.7 0.5 9.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat LRR_4 PF12799.7 EAU86058.2 - 0.41 11.1 7.7 15 6.2 0.0 4.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAU86058.2 - 7.7 7.5 7.1 41 5.3 0.1 5.0 5 1 0 5 5 4 0 Leucine Rich Repeat ABM PF03992.16 EAU86060.2 - 0.0025 17.9 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase BTB PF00651.31 EAU86061.1 - 0.00036 20.7 0.0 0.00071 19.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Lactamase_B PF00753.27 EAU86063.1 - 1.4e-11 44.8 0.7 2e-11 44.2 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAU86063.1 - 0.013 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAU86064.1 - 1.7e-09 38.0 0.1 4.6e-09 36.6 0.0 1.7 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAU86064.1 - 0.0045 16.5 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ufd2P_core PF10408.9 EAU86067.1 - 1.6e-216 720.7 0.1 2e-216 720.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EAU86067.1 - 5.6e-28 96.9 0.5 3.5e-27 94.4 0.4 2.5 2 0 0 2 2 2 1 U-box domain Spore_III_AB PF09548.10 EAU86067.1 - 2.2 8.4 3.6 1.2 9.2 0.1 2.5 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_L35p PF01632.19 EAU86068.1 - 3.9e-20 72.1 6.7 5.2e-20 71.7 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 zf-AN1 PF01428.16 EAU86069.1 - 1.4e-20 73.2 34.2 1.1e-11 44.7 8.4 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EAU86069.1 - 0.0086 16.4 23.2 0.041 14.2 6.8 2.7 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain Microtub_bind PF13931.6 EAU86069.1 - 0.15 12.5 4.3 0.76 10.2 4.8 2.0 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding DUF4294 PF14127.6 EAU86069.1 - 0.39 10.6 3.8 0.6 10.0 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) IBR PF01485.21 EAU86069.1 - 6.1 7.1 25.3 4.3 7.6 9.9 3.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain His_Phos_1 PF00300.22 EAU86070.1 - 2.3e-26 92.7 0.1 3.8e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2487 PF10673.9 EAU86070.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Eaf7 PF07904.13 EAU86071.1 - 1.3e-16 60.9 0.0 2.4e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Cyclin_N PF00134.23 EAU86072.2 - 4.9e-08 32.8 0.0 2.8e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain MBOAT_2 PF13813.6 EAU86073.2 - 8.4e-14 51.6 2.6 8.4e-14 51.6 2.6 2.8 3 1 1 4 4 4 1 Membrane bound O-acyl transferase family NicO PF03824.16 EAU86074.1 - 6e-35 121.0 0.0 9.6e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein TMEM100 PF16311.5 EAU86074.1 - 0.63 9.6 2.2 1.1 8.9 0.3 2.1 2 0 0 2 2 2 0 Transmembrane protein 100 adh_short PF00106.25 EAU86075.2 - 2e-12 47.0 0.0 8.6e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86075.2 - 6.5e-09 35.7 0.0 1.6e-08 34.4 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU86075.2 - 3.2e-08 33.7 0.0 4.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EAU86075.2 - 0.0017 18.6 0.1 0.003 17.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3842 PF12953.7 EAU86075.2 - 0.003 17.9 0.1 0.0053 17.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3842) HECT PF00632.25 EAU86077.2 - 2.6e-98 329.3 0.0 3.5e-98 328.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EAU86077.2 - 6.9e-38 128.4 16.9 1.6e-12 47.3 2.1 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EAU86077.2 - 2.2e-17 63.3 0.0 4.9e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain ParBc_2 PF08857.11 EAU86077.2 - 0.011 15.8 0.7 0.024 14.7 0.1 1.8 2 0 0 2 2 2 0 Putative ParB-like nuclease GPS PF01825.21 EAU86079.2 - 0.068 13.7 0.9 0.11 13.1 0.9 1.3 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif SRF-TF PF00319.18 EAU86081.2 - 7.5e-21 73.4 0.1 1.2e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PGA2 PF07543.12 EAU86081.2 - 0.66 10.0 2.9 2.6 8.0 0.2 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 PBP1_TM PF14812.6 EAU86081.2 - 4.9 7.6 9.9 5.5 7.4 1.7 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGEF PF00617.19 EAU86082.2 - 2.7e-26 92.9 0.1 1.1e-24 87.6 0.1 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EAU86082.2 - 1.5e-12 47.6 1.3 4.2e-12 46.2 1.3 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Rx_N PF18052.1 EAU86082.2 - 0.9 9.9 3.3 7.1 7.0 0.2 2.6 2 0 0 2 2 2 0 Rx N-terminal domain ETC_C1_NDUFA4 PF04800.12 EAU86085.1 - 5.5e-37 125.9 0.1 7.3e-37 125.5 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region RSN1_7TM PF02714.15 EAU86086.2 - 2.1e-32 112.5 24.8 8e-32 110.6 24.8 1.9 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EAU86086.2 - 3.3e-22 79.6 0.8 4.9e-15 56.2 0.0 3.7 3 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EAU86086.2 - 2.5e-12 46.8 1.0 2.5e-12 46.8 1.0 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport SPT2 PF08243.11 EAU86086.2 - 0.069 13.7 0.5 0.22 12.1 0.5 1.8 1 0 0 1 1 1 0 SPT2 chromatin protein TPR_19 PF14559.6 EAU86086.2 - 0.58 10.7 3.7 0.77 10.3 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GH131_N PF18271.1 EAU86087.1 - 6.8e-59 199.6 0.5 8.8e-59 199.3 0.5 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 EAU86087.1 - 9.9e-11 41.4 9.7 9.9e-11 41.4 9.7 2.0 1 1 0 1 1 1 1 Fungal cellulose binding domain Sod_Cu PF00080.20 EAU86088.1 - 9.6e-46 155.5 3.8 1.2e-45 155.2 3.8 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L1 PF00687.21 EAU86090.1 - 1.2e-55 188.5 0.5 1.2e-55 188.5 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Peptidase_S9 PF00326.21 EAU86091.2 - 1.9e-07 30.8 0.7 1.3e-06 28.1 0.7 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EAU86091.2 - 1.4e-06 27.7 0.1 7.9e-05 22.0 0.1 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAU86091.2 - 6.8e-05 22.6 0.1 0.0093 15.6 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.10 EAU86091.2 - 0.00024 20.3 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF915 PF06028.11 EAU86091.2 - 0.004 16.5 0.0 0.0076 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 EAU86091.2 - 0.0062 16.2 0.0 0.018 14.7 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.26 EAU86092.2 - 6e-24 84.5 0.1 1.2e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU86092.2 - 9.5e-16 59.1 0.1 2.2e-15 57.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU86092.2 - 1.3e-08 34.6 0.0 2.5e-06 27.3 0.0 2.7 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 EAU86092.2 - 0.015 15.4 0.4 4.6 7.4 0.1 2.4 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus AAA_5 PF07728.14 EAU86094.2 - 2.4e-114 377.4 0.0 3.6e-20 72.4 0.0 9.8 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EAU86094.2 - 3.4e-56 188.0 3.8 3.7e-22 78.5 0.0 5.9 5 0 0 5 5 5 4 Midasin AAA lid domain AAA_3 PF07726.11 EAU86094.2 - 3.5e-27 94.8 0.0 8.6e-11 41.8 0.0 8.3 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 EAU86094.2 - 1.4e-26 92.6 0.1 9.3e-26 90.0 0.0 2.5 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 EAU86094.2 - 5e-19 69.0 0.2 0.0016 18.8 0.0 7.1 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 EAU86094.2 - 9.4e-19 67.7 0.0 0.017 15.2 0.0 6.5 6 0 0 6 6 5 5 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 EAU86094.2 - 1.1e-18 67.4 0.2 0.0003 20.4 0.0 5.5 6 0 0 6 6 6 4 P-loop containing dynein motor region Sigma54_activat PF00158.26 EAU86094.2 - 6.9e-18 64.9 0.0 0.0045 16.7 0.0 6.1 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_16 PF13191.6 EAU86094.2 - 1.8e-16 61.0 19.0 0.0011 19.4 0.2 9.7 9 1 0 9 9 8 4 AAA ATPase domain AAA_6 PF12774.7 EAU86094.2 - 2.9e-15 56.1 0.0 0.096 11.6 0.0 7.6 7 0 0 7 7 7 3 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 EAU86094.2 - 1.1e-14 54.9 0.2 0.04 14.2 0.0 7.9 7 0 0 7 7 6 3 AAA domain AAA_14 PF13173.6 EAU86094.2 - 3e-10 40.2 0.0 0.04 13.9 0.0 6.7 7 0 0 7 7 6 1 AAA domain ABC_tran PF00005.27 EAU86094.2 - 1e-09 39.1 0.6 0.15 12.6 0.0 5.8 5 0 0 5 5 5 1 ABC transporter Sigma54_activ_2 PF14532.6 EAU86094.2 - 2.2e-09 37.6 0.4 0.0087 16.2 0.0 5.4 5 0 0 5 5 4 1 Sigma-54 interaction domain TsaE PF02367.17 EAU86094.2 - 3.6e-09 36.7 0.5 0.56 10.2 0.0 6.0 6 0 0 6 6 5 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EAU86094.2 - 6.3e-09 36.5 0.1 1.8 9.1 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_30 PF13604.6 EAU86094.2 - 2.9e-08 33.7 0.0 0.9 9.2 0.0 5.9 6 1 0 6 6 6 2 AAA domain T2SSE PF00437.20 EAU86094.2 - 2.2e-07 30.2 0.6 0.031 13.3 0.0 5.1 6 0 0 6 6 5 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EAU86094.2 - 1.1e-06 28.2 0.1 1.5 8.2 0.0 6.2 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EAU86094.2 - 1e-05 25.4 0.1 1.9 8.2 0.0 4.5 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EAU86094.2 - 2.8e-05 24.1 2.6 4.1 7.3 0.1 5.6 6 0 0 6 6 5 0 NACHT domain AAA_29 PF13555.6 EAU86094.2 - 3.1e-05 23.6 2.2 3.5 7.4 0.1 5.1 6 0 0 6 6 5 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 EAU86094.2 - 3.4e-05 24.2 0.5 28 5.1 0.0 5.6 6 0 0 6 6 5 0 RNA helicase AAA_19 PF13245.6 EAU86094.2 - 5.9e-05 23.4 2.4 1.2 9.5 0.1 4.4 4 0 0 4 4 3 1 AAA domain DUF815 PF05673.13 EAU86094.2 - 9.4e-05 21.7 0.0 2.3 7.3 0.0 4.0 4 0 0 4 4 3 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EAU86094.2 - 0.00012 21.4 1.1 6.3 6.0 0.0 6.6 8 0 0 8 8 8 0 Zeta toxin AAA_28 PF13521.6 EAU86094.2 - 0.00017 21.8 3.6 2.8 8.2 0.0 5.2 6 0 0 6 6 3 2 AAA domain TniB PF05621.11 EAU86094.2 - 0.00019 20.9 0.0 1.7 8.0 0.0 4.5 4 0 0 4 4 4 1 Bacterial TniB protein AAA_8 PF12780.7 EAU86094.2 - 0.00019 20.8 0.3 1.3 8.3 0.0 5.1 5 0 0 5 5 5 1 P-loop containing dynein motor region D4 AAA_33 PF13671.6 EAU86094.2 - 0.00024 21.3 0.1 29 4.8 0.0 5.3 5 0 0 5 5 5 0 AAA domain Roc PF08477.13 EAU86094.2 - 0.00029 21.0 0.9 3.3 7.9 0.0 4.6 5 0 0 5 5 4 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 EAU86094.2 - 0.00074 19.2 0.2 11 5.6 0.0 4.4 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EAU86094.2 - 0.00092 19.0 0.2 5.6 6.6 0.0 4.8 6 0 0 6 6 4 0 AAA domain ATPase_2 PF01637.18 EAU86094.2 - 0.0011 18.9 0.0 3.5 7.5 0.0 4.5 5 0 0 5 5 5 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EAU86094.2 - 0.0012 18.8 0.1 0.93 9.4 0.0 3.8 3 0 0 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EAU86094.2 - 0.0035 17.1 0.5 0.8 9.4 0.0 3.8 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EAU86094.2 - 0.0039 17.0 0.0 7.3 6.3 0.0 4.3 4 0 0 4 4 4 0 IstB-like ATP binding protein DEAD PF00270.29 EAU86094.2 - 0.0041 16.9 0.0 10 5.9 0.0 3.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_25 PF13481.6 EAU86094.2 - 0.0069 16.0 3.0 10 5.6 0.2 5.2 5 0 0 5 5 5 0 AAA domain ResIII PF04851.15 EAU86094.2 - 0.015 15.3 0.1 13 5.7 0.0 3.8 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 EAU86094.2 - 0.021 14.7 0.1 19 5.1 0.0 4.4 5 0 0 5 5 4 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EAU86094.2 - 0.062 13.4 2.1 14 5.8 0.0 4.4 5 0 0 5 5 4 0 50S ribosome-binding GTPase Bac_DnaA PF00308.18 EAU86094.2 - 0.069 13.0 0.0 6.3 6.6 0.0 3.4 3 0 0 3 3 3 0 Bacterial dnaA protein NTPase_1 PF03266.15 EAU86094.2 - 0.079 12.9 1.4 33 4.3 0.1 4.1 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.6 EAU86094.2 - 0.096 12.4 7.1 6.3 6.5 0.0 4.7 5 0 0 5 5 4 0 AAA domain dNK PF01712.19 EAU86094.2 - 0.11 12.3 0.4 10 5.9 0.0 3.8 4 0 0 4 4 3 0 Deoxynucleoside kinase AAA_23 PF13476.6 EAU86094.2 - 0.15 12.5 14.0 8.3 6.9 0.0 5.8 6 0 0 6 6 5 0 AAA domain ATP_bind_1 PF03029.17 EAU86094.2 - 0.39 10.5 1.8 18 5.0 0.1 3.4 4 0 0 4 4 2 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 EAU86094.2 - 2 7.7 3.3 36 3.6 0.0 3.7 4 0 0 4 4 3 0 KaiC tRNA-synt_1d PF00750.19 EAU86095.1 - 3e-103 345.4 3.1 3.9e-103 345.1 3.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EAU86095.1 - 1.1e-20 74.0 0.0 2.7e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2250 PF10007.9 EAU86095.1 - 0.0046 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) DALR_2 PF09190.11 EAU86095.1 - 0.1 13.1 0.1 0.52 10.8 0.1 2.3 2 0 0 2 2 2 0 DALR domain TBPIP PF07106.13 EAU86095.1 - 0.1 12.5 0.1 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain TrmB PF01978.19 EAU86095.1 - 0.12 12.3 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB F-box-like PF12937.7 EAU86096.1 - 1.4e-10 40.8 0.3 3.4e-10 39.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU86096.1 - 9.6 6.8 10.3 81 3.8 1.3 4.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) AAA PF00004.29 EAU86097.1 - 1.8e-39 135.2 0.0 3.6e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EAU86097.1 - 4.5e-20 71.4 0.0 8.6e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EAU86097.1 - 5.7e-12 45.3 0.1 1.4e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EAU86097.1 - 5.5e-05 23.6 0.3 0.015 15.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EAU86097.1 - 0.00029 20.8 0.0 0.0018 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EAU86097.1 - 0.00043 20.4 0.0 0.0021 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EAU86097.1 - 0.0027 18.0 0.8 0.25 11.6 0.1 2.8 2 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EAU86097.1 - 0.0036 17.1 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 EAU86097.1 - 0.008 15.7 0.1 0.08 12.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EAU86097.1 - 0.016 14.6 0.1 0.043 13.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EAU86097.1 - 0.021 15.0 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAU86097.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EAU86097.1 - 0.052 13.3 0.2 0.67 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAU86097.1 - 0.074 12.8 1.4 0.27 10.9 0.1 2.6 3 1 0 3 3 3 0 AAA domain DUF815 PF05673.13 EAU86097.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NuA4 PF09340.10 EAU86098.1 - 1.6e-25 88.7 0.3 1.6e-25 88.7 0.3 1.9 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Mod_r PF07200.13 EAU86099.2 - 4.6e-46 156.5 6.9 5.5e-46 156.3 6.9 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 EAU86099.2 - 0.0087 16.1 2.7 0.0087 16.1 2.7 1.6 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF5638 PF18688.1 EAU86099.2 - 0.042 14.2 0.8 0.088 13.1 0.7 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5638) ABC_tran_CTD PF16326.5 EAU86099.2 - 1.3 9.3 9.8 5 7.4 6.7 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain Glyco_hydro_61 PF03443.14 EAU86100.1 - 1.1e-62 211.6 0.0 1.5e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAU86100.1 - 1.3e-12 47.4 8.3 1.3e-12 47.4 8.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Pkinase PF00069.25 EAU86101.2 - 9.5e-43 146.5 0.0 1.4e-30 106.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86101.2 - 3.2e-31 108.6 0.0 1.9e-26 92.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU86101.2 - 0.0033 16.3 0.1 0.0033 16.3 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EAU86101.2 - 0.015 14.6 0.0 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 EAU86101.2 - 0.21 11.2 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SWI-SNF_Ssr4 PF08549.10 EAU86102.1 - 2.6e-26 92.5 5.4 4.8e-19 68.5 0.0 2.3 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1750) DUF1192 PF06698.11 EAU86102.1 - 0.0092 16.0 0.3 0.0092 16.0 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) CG-1 PF03859.16 EAU86102.1 - 0.066 13.0 0.1 0.3 10.9 0.0 2.1 2 1 0 2 2 2 0 CG-1 domain DUF1840 PF08895.11 EAU86102.1 - 3.9 7.8 5.8 7.2 7.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) F-box-like PF12937.7 EAU86103.2 - 0.00011 22.1 0.1 0.00031 20.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86103.2 - 0.0026 17.6 3.5 0.0065 16.3 0.1 3.1 3 0 0 3 3 3 1 F-box domain UAA PF08449.11 EAU86104.1 - 1.5e-45 155.8 8.9 3.4e-45 154.6 7.6 1.8 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 EAU86104.1 - 2e-09 37.7 21.0 3.9e-07 30.3 9.4 4.0 4 1 0 4 4 4 2 EamA-like transporter family CRT-like PF08627.10 EAU86104.1 - 0.0012 17.9 5.5 0.018 14.0 0.3 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 EAU86104.1 - 0.0012 18.3 4.4 0.24 10.7 0.9 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EAU86104.1 - 0.0065 15.7 5.8 0.67 9.1 0.7 2.6 2 1 0 2 2 2 2 Nucleotide-sugar transporter Connexin PF00029.19 EAU86104.1 - 0.031 14.0 0.2 0.084 12.6 0.0 1.7 2 0 0 2 2 2 0 Connexin DSPc PF00782.20 EAU86105.2 - 8.7e-24 83.8 0.0 1.2e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EAU86105.2 - 0.0056 17.0 0.0 0.0089 16.3 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain SGS PF05002.15 EAU86105.2 - 0.057 13.5 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 SGS domain cobW PF02492.19 EAU86106.2 - 1.1e-44 152.2 0.0 1.5e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EAU86106.2 - 4.7e-05 23.0 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain CobW_C PF07683.14 EAU86106.2 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EAU86106.2 - 0.0017 18.3 0.0 0.44 10.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EAU86106.2 - 0.0024 18.2 0.0 0.0072 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EAU86106.2 - 0.0028 17.7 0.0 0.0092 16.1 0.0 1.9 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EAU86106.2 - 0.0059 16.8 0.0 0.0094 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 EAU86106.2 - 0.012 15.0 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 EAU86106.2 - 0.036 13.0 0.0 0.31 10.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EAU86106.2 - 0.061 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EAU86106.2 - 0.074 13.0 0.1 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EAU86106.2 - 0.087 12.5 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EAU86106.2 - 0.11 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DNA_pol_E_B PF04042.16 EAU86107.1 - 2e-32 112.3 0.1 3.4e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EAU86107.1 - 1.8e-22 80.5 2.6 1.6e-11 44.6 0.7 2.2 1 1 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal Nitr_red_assoc PF09655.10 EAU86107.1 - 0.087 13.5 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF4131 PF13567.6 EAU86107.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Endosulfine PF04667.17 EAU86108.2 - 1.9e-26 92.0 0.2 3.8e-26 91.0 0.2 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region N_NLPC_P60 PF12912.7 EAU86110.2 - 0.17 12.3 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Pkinase PF00069.25 EAU86111.2 - 4.2e-63 213.2 0.0 8.9e-63 212.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86111.2 - 2.5e-36 125.3 0.0 4.3e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EAU86111.2 - 4.5e-20 71.3 29.2 6.2e-12 45.2 10.5 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 EAU86111.2 - 4.4e-15 55.5 15.4 8.5e-12 45.0 3.2 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 EAU86111.2 - 1.5e-10 41.6 0.5 5.2e-10 39.9 0.5 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EAU86111.2 - 0.05 12.6 0.1 0.082 11.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EAU86111.2 - 0.052 13.2 0.3 2.7 7.6 0.1 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 C1_2 PF03107.16 EAU86111.2 - 0.15 12.4 23.3 0.27 11.6 7.9 2.4 2 0 0 2 2 2 0 C1 domain Peptidase_M64 PF09471.10 EAU86114.2 - 1.9e-06 27.6 0.1 5.9e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 IgA Peptidase M64 EHN PF06441.12 EAU86115.1 - 6.7e-35 119.7 1.4 2.4e-33 114.8 0.0 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EAU86115.1 - 8.1e-15 55.2 0.0 1.3e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU86115.1 - 0.0018 18.9 2.4 0.0018 18.9 2.4 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family F-box-like PF12937.7 EAU86116.2 - 2.8e-07 30.3 1.3 7.2e-07 29.0 0.2 2.3 2 0 0 2 2 2 1 F-box-like DNA_pol_B_exo1 PF03104.19 EAU86117.2 - 2.8e-34 118.8 0.0 3.1e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 EAU86117.2 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Methyltransf_33 PF10017.9 EAU86119.2 - 8.2e-56 189.4 0.0 9.9e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_33 PF10017.9 EAU86120.2 - 3e-16 59.5 0.0 3.5e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Glyco_hydro_15 PF00723.21 EAU86122.2 - 9.5e-90 301.5 0.0 1.1e-89 301.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EAU86122.2 - 2.4e-19 69.0 0.0 5.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain zf-RING_2 PF13639.6 EAU86123.1 - 1.3e-11 44.7 3.6 2.9e-11 43.5 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EAU86123.1 - 1e-10 41.2 2.8 2.3e-10 40.0 2.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 EAU86123.1 - 2.4e-08 33.9 0.0 5.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 EAU86123.1 - 1.8e-06 27.8 1.4 3.8e-06 26.7 1.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAU86123.1 - 1.9e-05 24.4 3.3 3.9e-05 23.4 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU86123.1 - 8.8e-05 22.3 2.2 0.00017 21.4 2.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU86123.1 - 0.00018 21.3 2.1 0.00039 20.2 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU86123.1 - 0.00031 21.0 7.0 0.0017 18.6 6.2 2.4 1 1 1 2 2 2 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EAU86123.1 - 0.004 16.7 2.8 0.0088 15.6 2.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EAU86123.1 - 0.0058 16.6 0.2 0.0058 16.6 0.2 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAU86123.1 - 0.013 15.5 2.8 0.044 13.8 2.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 EAU86123.1 - 0.15 12.2 0.7 0.3 11.3 0.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family Prok-RING_4 PF14447.6 EAU86123.1 - 0.19 11.6 6.8 0.039 13.8 2.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EAU86123.1 - 0.2 11.8 3.2 1.2 9.4 3.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PAS_3 PF08447.12 EAU86124.2 - 1.6e-08 34.7 0.0 3.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EAU86124.2 - 0.00019 21.4 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EAU86124.2 - 0.0033 17.5 0.0 0.01 15.9 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EAU86124.2 - 0.025 14.8 0.0 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 PAS fold Abhydrolase_1 PF00561.20 EAU86125.1 - 3.6e-19 69.4 0.0 2.1e-18 66.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU86125.1 - 2.5e-16 61.0 0.1 3.5e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU86125.1 - 4.9e-07 29.2 0.0 2.2e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1100 PF06500.11 EAU86125.1 - 0.05 12.4 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.7 EAU86125.1 - 0.058 13.2 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 EAU86125.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Aldolase_II PF00596.21 EAU86126.2 - 1.6e-41 142.3 0.0 1.8e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_M15_4 PF13539.6 EAU86126.2 - 0.13 12.8 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase DEAD PF00270.29 EAU86127.2 - 4.1e-23 82.0 0.0 1.1e-22 80.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU86127.2 - 7e-17 61.8 0.0 7.9e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EAU86127.2 - 1.3e-07 32.3 0.6 3.7e-07 30.8 0.6 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EAU86127.2 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAU86127.2 - 0.0087 16.3 0.2 0.051 13.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU86127.2 - 0.04 13.6 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.14 EAU86127.2 - 0.13 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Fasciclin PF02469.22 EAU86128.1 - 1.2e-41 142.0 0.1 2.3e-23 82.8 0.1 2.4 2 1 0 2 2 2 2 Fasciclin domain Abhydrolase_3 PF07859.13 EAU86130.1 - 5.6e-14 52.5 0.0 1.5e-09 38.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU86130.1 - 1.5e-05 24.6 0.4 0.0046 16.5 0.0 2.4 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EAU86130.1 - 0.0018 17.2 0.0 0.018 14.0 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_1 PF00561.20 EAU86130.1 - 0.028 14.0 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 EAU86130.1 - 0.045 13.3 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EAU86130.1 - 0.049 12.9 0.1 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EAU86130.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 EAU86131.2 - 6.3e-07 29.1 0.0 0.0084 15.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EAU86131.2 - 9.5e-07 28.9 0.0 0.00026 20.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 EAU86131.2 - 0.0079 15.8 0.3 0.48 9.9 0.0 2.5 3 0 0 3 3 3 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EAU86131.2 - 0.041 14.5 0.6 0.067 13.8 0.6 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 EAU86134.2 - 7.6e-16 58.0 47.0 1.5e-11 43.9 23.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily GntR PF00392.21 EAU86135.2 - 0.065 12.9 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family HTH_36 PF13730.6 EAU86135.2 - 0.07 13.1 0.0 0.82 9.7 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain zf-MYND PF01753.18 EAU86136.2 - 0.00045 20.2 1.8 0.00094 19.2 1.8 1.5 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 EAU86137.2 - 2.4e-07 30.5 0.4 2.4e-07 30.5 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU86137.2 - 1.1e-05 25.2 1.3 9.9e-05 22.1 1.3 2.6 1 1 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EAU86137.2 - 0.0022 17.8 0.1 0.18 11.7 0.0 3.0 3 0 0 3 3 3 1 F-box A_deaminase PF00962.22 EAU86138.2 - 2.1e-121 405.2 0.1 2.8e-121 404.9 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2235 PF09994.9 EAU86139.2 - 1.2e-86 290.6 0.0 1.5e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 EAU86139.2 - 0.038 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal zf-MYND PF01753.18 EAU86142.2 - 4.2e-09 36.3 13.5 9e-09 35.3 13.5 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU86142.2 - 0.78 10.1 8.6 2.2 8.6 8.6 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-NADH-PPase PF09297.11 EAU86142.2 - 0.95 9.2 5.8 6.5 6.5 1.7 2.7 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain PolC_DP2 PF03833.13 EAU86142.2 - 1.3 6.8 3.8 1.8 6.3 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DJ-1_PfpI PF01965.24 EAU86143.1 - 5.5e-12 45.8 0.0 7.9e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Dynamin_N PF00350.23 EAU86144.1 - 3.7e-18 66.1 0.5 1.2e-17 64.5 0.1 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EAU86144.1 - 6.7e-13 48.7 0.1 6.6e-12 45.5 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAU86144.1 - 1.5e-08 34.5 0.4 8.3e-08 32.0 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAU86144.1 - 6.2e-05 23.0 2.5 0.023 14.6 0.4 2.7 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 EAU86144.1 - 0.00026 20.7 0.1 0.03 13.9 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.12 EAU86144.1 - 0.0031 16.9 0.2 0.0078 15.6 0.2 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EAU86144.1 - 0.0033 17.6 0.0 1.7 8.9 0.0 3.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EAU86144.1 - 0.004 16.3 0.0 0.0081 15.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Arf PF00025.21 EAU86144.1 - 0.038 13.4 0.3 9.4 5.7 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_29 PF13555.6 EAU86144.1 - 0.041 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 EAU86144.1 - 0.057 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 EAU86144.1 - 0.15 11.5 0.1 8.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B adh_short PF00106.25 EAU86146.2 - 4.7e-26 91.5 0.0 2e-21 76.4 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86146.2 - 4.5e-17 62.4 0.0 6.4e-13 48.8 0.0 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU86146.2 - 3e-06 27.2 0.2 5.6e-06 26.4 0.0 1.4 2 0 0 2 2 2 1 KR domain ArenaCapSnatch PF17296.2 EAU86146.2 - 0.029 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Arenavirus cap snatching domain Polysacc_synt_2 PF02719.15 EAU86146.2 - 0.046 12.8 0.0 0.062 12.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_10 PF13374.6 EAU86147.2 - 2.7e-67 221.0 0.6 2.3e-06 27.3 0.0 12.7 11 1 1 12 12 12 10 Tetratricopeptide repeat CHAT PF12770.7 EAU86147.2 - 3.7e-26 92.2 0.0 8e-26 91.1 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU86147.2 - 4.3e-24 84.6 4.1 0.0059 16.9 0.0 11.3 10 2 1 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 EAU86147.2 - 1.4e-08 34.5 9.9 1.5 9.4 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat MAGI_u1 PF16663.5 EAU86147.2 - 0.00011 22.2 0.0 11 6.2 0.0 5.6 6 0 0 6 6 6 1 Unstructured region on MAGI TPR_1 PF00515.28 EAU86147.2 - 0.06 13.2 21.7 58 3.7 0.0 12.1 16 1 1 17 17 17 0 Tetratricopeptide repeat Glyco_hydro_65N PF03636.15 EAU86147.2 - 0.17 11.5 0.0 69 3.0 0.0 4.2 3 2 2 5 5 5 0 Glycosyl hydrolase family 65, N-terminal domain TPR_16 PF13432.6 EAU86147.2 - 0.27 11.9 8.2 12 6.7 0.1 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3158 PF11358.8 EAU86147.2 - 0.49 10.1 2.2 25 4.5 0.0 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF3158) F-box-like PF12937.7 EAU86148.1 - 2.5e-08 33.7 3.6 8.3e-08 32.0 3.6 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU86148.1 - 0.036 14.5 3.9 11 6.5 0.5 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Nipped-B_C PF12830.7 EAU86150.2 - 1.4e-34 119.7 2.1 8.2e-34 117.2 2.1 2.4 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EAU86150.2 - 1.4e-13 50.9 0.5 2.1e-11 43.9 0.1 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EAU86150.2 - 2e-05 24.4 0.2 0.78 10.2 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 EAU86150.2 - 0.0036 17.7 1.3 0.025 15.0 0.2 3.2 2 1 0 2 2 2 1 HEAT repeats Cnd1 PF12717.7 EAU86150.2 - 0.0047 17.0 0.0 0.022 14.8 0.0 2.2 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 TMEM252 PF15664.5 EAU86150.2 - 0.062 13.0 3.2 0.064 13.0 1.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 252 family PMC2NT PF08066.12 EAU86150.2 - 0.27 12.0 5.7 37 5.1 0.0 5.1 4 0 0 4 4 4 0 PMC2NT (NUC016) domain HA2 PF04408.23 EAU86151.2 - 4e-18 65.7 0.0 9.9e-18 64.4 0.0 1.8 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAU86151.2 - 1e-12 48.3 0.0 2.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EAU86151.2 - 3.2e-07 30.6 0.0 8.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EAU86151.2 - 1.7e-06 27.9 0.1 3.9e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU86151.2 - 0.00034 20.9 0.0 0.00078 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU86151.2 - 0.0018 18.0 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU86151.2 - 0.0055 17.1 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EAU86151.2 - 0.029 14.3 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 EAU86151.2 - 0.049 13.0 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EAU86151.2 - 0.054 12.9 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 EAU86151.2 - 0.092 13.3 0.3 0.99 9.9 0.3 2.3 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EAU86151.2 - 0.12 12.2 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EAU86151.2 - 0.19 12.2 0.1 0.57 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Patatin PF01734.22 EAU86152.2 - 1.4e-24 87.4 0.1 3e-24 86.4 0.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase CN_hydrolase PF00795.22 EAU86153.2 - 7.2e-19 68.1 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2235 PF09994.9 EAU86154.2 - 2.2e-89 299.7 0.1 3e-89 299.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TPR_10 PF13374.6 EAU86155.1 - 7.7e-48 159.1 10.7 1.4e-08 34.3 0.1 9.2 7 1 1 8 8 8 7 Tetratricopeptide repeat CHAT PF12770.7 EAU86155.1 - 2e-25 89.8 0.0 4.1e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU86155.1 - 3.7e-21 75.2 8.7 0.03 14.6 0.0 9.1 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 EAU86155.1 - 2.4e-10 40.1 8.2 2.4 8.7 0.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat CNDH2_M PF16869.5 EAU86155.1 - 0.022 15.5 2.0 5.8 7.6 0.0 4.1 3 1 1 4 4 4 0 PF16858 Glyco_hydro_65N PF03636.15 EAU86155.1 - 0.17 11.5 0.0 33 4.0 0.0 3.7 4 1 0 4 4 4 0 Glycosyl hydrolase family 65, N-terminal domain TPR_1 PF00515.28 EAU86155.1 - 0.34 10.8 15.9 60 3.7 0.0 9.8 13 0 0 13 13 13 0 Tetratricopeptide repeat AMPKBI PF04739.15 EAU86156.1 - 5.6e-26 90.6 3.6 8.2e-25 86.9 2.4 3.1 1 1 1 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EAU86156.1 - 7.5e-19 67.7 0.0 1.3e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pkinase PF00069.25 EAU86157.2 - 5.8e-66 222.6 0.0 8.6e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86157.2 - 2.9e-35 121.8 0.0 7.6e-35 120.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU86157.2 - 0.0026 17.1 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EAU86157.2 - 0.0033 16.5 0.1 0.0053 15.9 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAU86157.2 - 0.017 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EAU86157.2 - 0.065 12.2 0.1 0.088 11.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EAU86157.2 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 EAU86163.2 - 2.8e-102 342.3 0.0 4.6e-81 272.4 0.0 2.0 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EAU86163.2 - 2.7e-09 37.0 0.0 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 EAU86163.2 - 0.00019 21.1 0.6 0.00055 19.6 0.6 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Amino_oxidase PF01593.24 EAU86166.1 - 1.4e-33 116.9 0.0 1.9e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAU86166.1 - 3.7e-11 43.1 3.6 1.5e-10 41.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAU86166.1 - 8.5e-06 25.8 3.9 0.019 15.0 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EAU86166.1 - 1.3e-05 25.0 0.3 1.3e-05 25.0 0.3 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EAU86166.1 - 0.00022 20.5 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EAU86166.1 - 0.00069 18.4 0.0 0.91 8.2 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EAU86166.1 - 0.0045 16.3 0.4 0.24 10.6 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU86166.1 - 0.0078 15.3 0.0 4.3 6.3 0.0 2.6 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 EAU86166.1 - 0.075 13.6 1.0 1.3 9.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EAU86166.1 - 0.14 10.6 0.0 5.7 5.4 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MCRA PF06100.11 EAU86166.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 EAU86166.1 - 0.18 11.0 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CHAT PF12770.7 EAU86167.2 - 1.5e-28 100.1 0.0 2.8e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EAU86167.2 - 9e-27 92.2 10.4 2e-08 33.8 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 EAU86167.2 - 1.7e-08 34.6 11.4 0.18 12.1 0.0 7.2 5 3 3 8 8 8 3 Tetratricopeptide repeat Sel1 PF08238.12 EAU86167.2 - 0.1 13.3 0.1 1.1 10.0 0.0 2.9 2 0 0 2 2 2 0 Sel1 repeat TPR_2 PF07719.17 EAU86167.2 - 0.33 11.2 7.0 33 4.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU86167.2 - 3.8 7.5 5.3 43 4.2 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU86168.2 - 1.3e-111 361.8 39.5 4e-08 32.9 0.1 16.0 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_12 PF13424.6 EAU86168.2 - 1.4e-39 134.2 35.5 0.037 14.3 0.0 16.0 16 1 0 16 16 16 13 Tetratricopeptide repeat CHAT PF12770.7 EAU86168.2 - 3.4e-31 108.8 0.0 1.1e-30 107.1 0.0 1.8 2 0 0 2 2 2 1 CHAT domain TPR_17 PF13431.6 EAU86168.2 - 1.9e-20 71.7 10.6 7.2 7.2 0.0 13.7 13 0 0 13 13 13 4 Tetratricopeptide repeat Yopt PF09467.10 EAU86168.2 - 6.1e-08 32.6 1.1 41 4.3 0.0 9.8 12 0 0 12 12 12 0 Hypothetical protein Yopt MAGI_u1 PF16663.5 EAU86168.2 - 0.00075 19.5 0.0 2.7e+02 1.8 0.0 7.6 12 0 0 12 12 12 0 Unstructured region on MAGI DUF4404 PF14357.6 EAU86168.2 - 0.016 15.9 15.7 48 4.7 0.1 8.8 8 4 2 10 10 10 0 Domain of unknown function (DUF4404) TPR_14 PF13428.6 EAU86168.2 - 0.025 15.4 41.0 2.7e+02 2.8 0.0 17.0 19 2 2 21 21 21 0 Tetratricopeptide repeat Lantibiotic_a PF14867.6 EAU86168.2 - 0.045 13.5 0.4 69 3.3 0.0 5.0 6 0 0 6 6 6 0 Lantibiotic alpha UBA_4 PF14555.6 EAU86168.2 - 10 6.1 12.0 3.2e+02 1.3 0.1 7.1 7 0 0 7 7 7 0 UBA-like domain zf-MYND PF01753.18 EAU86169.2 - 9.6e-09 35.2 8.4 9.6e-09 35.2 8.4 2.7 2 1 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EAU86169.2 - 0.0019 18.3 2.3 0.0019 18.3 2.3 2.2 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 Secretin_N_2 PF07655.13 EAU86169.2 - 0.81 10.3 7.0 1.8 9.2 7.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain F-box-like PF12937.7 EAU86170.2 - 1e-14 54.1 0.8 2.2e-14 53.1 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86170.2 - 3.9e-05 23.4 0.1 0.0003 20.6 0.2 2.5 2 0 0 2 2 2 1 F-box domain DivIC PF04977.15 EAU86170.2 - 0.012 15.4 1.0 0.037 13.8 1.1 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 EAU86170.2 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF465 PF04325.13 EAU86170.2 - 0.084 12.9 1.5 0.16 12.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) FlxA PF14282.6 EAU86170.2 - 0.17 11.9 1.0 0.33 11.0 1.0 1.4 1 0 0 1 1 1 0 FlxA-like protein Pmp3 PF01679.17 EAU86171.2 - 4.3 7.6 6.3 0.97 9.7 1.4 2.2 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Ribonuc_red_lgC PF02867.15 EAU86172.2 - 1.3e-179 598.1 0.0 1.7e-179 597.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EAU86172.2 - 3.1e-24 84.8 0.1 7.9e-24 83.5 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EAU86172.2 - 7.3e-13 48.9 1.2 1.3e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain Gal11_ABD1 PF18535.1 EAU86172.2 - 0.099 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) DUF4813 PF16072.5 EAU86172.2 - 7.7 6.1 21.5 14 5.3 21.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) CE2_N PF17996.1 EAU86173.2 - 3.8e-08 33.3 0.0 0.0003 20.7 0.0 2.6 3 0 0 3 3 3 2 Carbohydrate esterase 2 N-terminal CHRD PF07452.12 EAU86173.2 - 0.12 13.3 1.2 1.1 10.3 0.0 2.5 2 1 0 2 2 2 0 CHRD domain Aldo_ket_red PF00248.21 EAU86176.2 - 7.3e-35 120.6 0.0 7.8e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family RHH_1 PF01402.21 EAU86176.2 - 0.017 15.0 0.1 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family DUF3701 PF12482.8 EAU86176.2 - 0.071 13.2 0.4 0.66 10.1 0.1 2.4 2 0 0 2 2 2 0 Phage integrase protein U79_P34 PF03064.16 EAU86179.2 - 5.2 6.3 9.5 11 5.3 9.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HTH_Mga PF08280.11 EAU86180.2 - 0.68 10.0 6.2 7 6.8 6.2 2.1 1 1 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Pkinase_Tyr PF07714.17 EAU86182.2 - 8.1e-42 143.3 0.0 1.2e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU86182.2 - 6.3e-31 107.7 0.0 1.3e-30 106.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain PH_10 PF15411.6 EAU86182.2 - 0.00053 20.2 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RIO1 PF01163.22 EAU86182.2 - 0.035 13.7 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family CDC24 PF06395.11 EAU86182.2 - 0.094 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin CH PF00307.31 EAU86184.2 - 5.3e-47 158.5 0.0 1.3e-24 86.5 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain Cofilin_ADF PF00241.20 EAU86184.2 - 4.5e-42 142.7 0.8 1.6e-41 140.9 0.8 2.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EFhand_Ca_insen PF08726.10 EAU86184.2 - 4.8e-14 52.2 0.8 5.6e-13 48.8 0.0 3.0 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EAU86184.2 - 4.6e-13 48.8 0.0 3.7e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Tektin PF03148.14 EAU86184.2 - 0.0034 16.2 3.4 0.0065 15.3 3.4 1.5 1 1 0 1 1 1 1 Tektin family Spc7 PF08317.11 EAU86184.2 - 0.0046 15.9 4.0 0.0046 15.9 4.0 2.0 2 0 0 2 2 2 1 Spc7 kinetochore protein EF-hand_14 PF17959.1 EAU86184.2 - 0.014 15.7 0.4 7 7.1 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_6 PF13405.6 EAU86184.2 - 0.024 14.5 0.0 0.096 12.7 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Baculo_PEP_C PF04513.12 EAU86184.2 - 0.3 11.1 1.9 1.2 9.2 0.2 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3106 PF11304.8 EAU86184.2 - 0.84 10.1 7.9 0.67 10.5 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3106) DMPK_coil PF08826.10 EAU86184.2 - 0.89 9.7 5.9 7.9 6.7 0.1 3.5 3 0 0 3 3 3 0 DMPK coiled coil domain like AAA_23 PF13476.6 EAU86184.2 - 1.7 9.1 6.3 2.4 8.6 2.6 2.5 2 0 0 2 2 2 0 AAA domain Apolipoprotein PF01442.18 EAU86184.2 - 2 8.3 10.5 0.49 10.3 5.6 2.3 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Spectrin PF00435.21 EAU86184.2 - 4.6 7.8 11.4 2 8.9 1.7 3.8 2 1 2 4 4 4 0 Spectrin repeat POB3_N PF17292.2 EAU86185.2 - 1.9e-31 108.4 0.2 8e-28 96.7 0.1 2.8 2 1 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 EAU86185.2 - 1.3e-25 89.1 0.0 4.1e-25 87.5 0.0 2.0 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EAU86185.2 - 3.2e-21 75.5 0.1 8.6e-20 71.0 0.1 2.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH PF00169.29 EAU86186.1 - 0.00031 21.2 0.6 0.00063 20.2 0.6 1.4 1 0 0 1 1 1 1 PH domain RasGEF PF00617.19 EAU86187.2 - 2.2e-52 177.8 0.1 3.8e-52 177.1 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RNA_pol_Rpb1_7 PF04990.12 EAU86187.2 - 0.032 14.2 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 adh_short PF00106.25 EAU86188.2 - 1.5e-25 89.9 0.1 1.7e-13 50.5 0.1 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86188.2 - 5.1e-12 45.9 0.0 0.00015 21.4 0.0 3.1 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAU86188.2 - 1.1e-06 28.3 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAU86188.2 - 5e-05 23.3 0.0 9.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EAU86188.2 - 0.0028 17.1 0.2 0.0049 16.3 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAU86188.2 - 0.0032 16.7 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EAU86188.2 - 0.07 13.0 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_7 PF13241.6 EAU86188.2 - 0.071 13.6 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 EAU86189.2 - 3.1e-23 82.3 0.0 1.8e-11 43.9 0.0 3.1 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86189.2 - 1.2e-10 41.3 0.0 0.025 14.2 0.0 3.1 3 0 0 3 3 3 3 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAU86189.2 - 0.00061 19.3 0.0 0.00086 18.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAU86189.2 - 0.0014 18.5 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAU86189.2 - 0.022 13.9 0.0 0.057 12.5 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 EAU86189.2 - 0.058 13.8 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 EAU86189.2 - 0.088 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Moricin PF06451.11 EAU86189.2 - 0.089 12.6 0.1 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Moricin DIOX_N PF14226.6 EAU86190.2 - 8.1e-32 110.5 0.0 1.5e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAU86190.2 - 7.6e-20 71.3 0.0 1.2e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_25 PF13649.6 EAU86192.1 - 1.4e-10 41.8 0.0 2.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAU86192.1 - 4.4e-10 39.4 0.0 6.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EAU86192.1 - 1.2e-08 35.4 0.0 3.1e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU86192.1 - 5.7e-08 32.7 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU86192.1 - 7.4e-08 32.4 0.0 6e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAU86192.1 - 0.00035 20.2 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EAU86192.1 - 0.00056 20.6 0.0 0.0013 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EAU86192.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EAU86192.1 - 0.013 16.5 0.1 0.056 14.5 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EAU86192.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 EAU86192.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EAU86192.1 - 0.031 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 EAU86192.1 - 0.045 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EAU86192.1 - 0.052 13.0 0.1 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB Met_10 PF02475.16 EAU86192.1 - 0.055 13.2 0.1 0.089 12.5 0.1 1.2 1 0 0 1 1 1 0 Met-10+ like-protein ADH_zinc_N PF00107.26 EAU86192.1 - 0.097 12.6 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Methyltransf_16 PF10294.9 EAU86192.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase SPX PF03105.19 EAU86193.1 - 6.8 6.5 13.6 8.5 6.2 13.6 1.1 1 0 0 1 1 1 0 SPX domain NFACT-R_1 PF05670.13 EAU86194.1 - 7e-42 142.5 0.0 1.1e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain RRM_1 PF00076.22 EAU86195.2 - 3.8e-09 36.3 0.0 8.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EAU86195.2 - 1.6e-05 25.1 0.3 4.4e-05 23.7 0.3 1.7 1 0 0 1 1 1 1 PWI domain Trehalase PF01204.18 EAU86196.1 - 1.1e-106 357.7 0.4 4.5e-96 322.7 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 EAU86196.1 - 0.0013 17.7 0.1 0.0035 16.3 0.0 1.6 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase COesterase PF00135.28 EAU86197.2 - 2.3e-89 300.6 0.0 2.9e-88 297.0 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU86197.2 - 3.2e-06 27.2 0.2 0.00022 21.1 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU86197.2 - 0.0021 17.5 0.2 0.0077 15.7 0.3 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AAA PF00004.29 EAU86198.2 - 3e-39 134.4 0.0 6.3e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU86198.2 - 6.3e-11 41.9 0.3 1.6e-10 40.6 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 EAU86198.2 - 5.2e-07 29.5 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EAU86198.2 - 6e-05 23.2 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EAU86198.2 - 9.9e-05 22.4 0.4 0.0017 18.4 0.4 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU86198.2 - 0.00013 22.4 0.1 0.003 18.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EAU86198.2 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EAU86198.2 - 0.00023 21.1 0.1 0.00078 19.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 EAU86198.2 - 0.00024 21.7 0.1 0.0011 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU86198.2 - 0.00028 21.2 0.2 0.0079 16.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EAU86198.2 - 0.00053 19.4 0.3 0.003 17.0 0.3 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAU86198.2 - 0.0011 18.8 0.1 0.0027 17.5 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EAU86198.2 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EAU86198.2 - 0.002 18.3 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain TniB PF05621.11 EAU86198.2 - 0.0026 17.2 0.3 2 7.8 0.0 2.5 2 1 1 3 3 2 2 Bacterial TniB protein RNA_helicase PF00910.22 EAU86198.2 - 0.0028 18.0 0.0 0.0075 16.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.6 EAU86198.2 - 0.0066 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EAU86198.2 - 0.0068 15.7 0.3 0.013 14.7 0.2 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain Hydin_ADK PF17213.3 EAU86198.2 - 0.0084 16.4 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 EAU86198.2 - 0.0098 16.3 0.0 0.032 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EAU86198.2 - 0.014 14.9 0.1 0.044 13.3 0.0 1.8 2 0 0 2 2 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EAU86198.2 - 0.026 13.8 0.1 0.044 13.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EAU86198.2 - 0.029 14.1 0.1 0.052 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU86198.2 - 0.033 13.7 0.2 0.27 10.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EAU86198.2 - 0.043 13.7 0.0 0.095 12.6 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAU86198.2 - 0.044 13.5 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 EAU86198.2 - 0.048 13.0 0.0 0.78 9.0 0.0 2.3 1 1 1 2 2 2 0 KaiC Viral_helicase1 PF01443.18 EAU86198.2 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EAU86198.2 - 0.074 13.6 0.0 0.14 12.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 EAU86198.2 - 0.075 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IPT PF01745.16 EAU86198.2 - 0.092 12.1 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Isopentenyl transferase NACHT PF05729.12 EAU86198.2 - 0.1 12.5 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.21 EAU86198.2 - 0.11 12.1 0.1 0.45 10.2 0.0 2.1 3 0 0 3 3 1 0 Guanylate kinase Parvo_NS1 PF01057.17 EAU86198.2 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ALG11_N PF15924.5 EAU86200.2 - 3.9e-82 275.3 0.1 5.8e-82 274.8 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EAU86200.2 - 3.2e-22 78.9 0.0 6.3e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAU86200.2 - 1.6e-11 44.8 0.0 3.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EAU86200.2 - 0.01 16.2 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2220 PF09983.9 EAU86200.2 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) FMN_dh PF01070.18 EAU86201.2 - 6.9e-112 373.9 0.0 8.4e-112 373.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EAU86201.2 - 3e-06 26.7 0.0 0.04 13.2 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EAU86201.2 - 5.8e-06 25.5 1.6 0.00011 21.4 0.6 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EAU86201.2 - 0.00015 21.1 0.0 0.00022 20.5 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EAU86201.2 - 0.0024 17.3 0.3 0.0037 16.7 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EAU86201.2 - 0.0042 16.6 0.1 0.39 10.1 0.1 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein Sad1_UNC PF07738.13 EAU86202.2 - 1.4e-29 102.8 0.0 2.5e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CCDC158 PF15921.5 EAU86202.2 - 0.1 10.4 3.5 0.17 9.7 3.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 TraC PF07820.12 EAU86202.2 - 0.33 11.3 1.5 2 8.8 0.1 2.7 2 0 0 2 2 2 0 TraC-like protein Prenyltrans PF00432.21 EAU86203.2 - 7.3e-38 128.0 4.4 3.7e-12 45.8 0.9 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EAU86203.2 - 8.3e-06 25.1 0.0 0.066 12.3 0.0 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EAU86203.2 - 0.0035 16.5 0.0 0.29 10.2 0.0 2.4 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain NOT2_3_5 PF04153.18 EAU86204.2 - 1.9e-29 102.4 0.4 5.7e-29 100.8 0.4 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RNA_pol_Rpb4 PF03874.16 EAU86205.1 - 2.7e-24 85.8 3.1 3.5e-24 85.5 3.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.21 EAU86205.1 - 0.00079 19.7 1.2 0.0029 17.9 0.1 2.2 2 0 0 2 2 2 1 Death effector domain EzrA PF06160.12 EAU86205.1 - 0.02 13.1 2.2 0.024 12.8 1.8 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA ENTH PF01417.20 EAU86208.1 - 2.3e-44 150.4 0.0 3.6e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 EAU86208.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain Glyco_hydro_20 PF00728.22 EAU86209.2 - 1.9e-85 287.4 0.2 2.6e-85 286.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EAU86209.2 - 1.1e-15 58.5 0.0 3.6e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EAU86209.2 - 1.9e-09 38.3 0.0 2.8e-08 34.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Bromo_TP PF07524.13 EAU86209.2 - 0.18 11.8 0.1 0.78 9.8 0.1 2.0 2 0 0 2 2 2 0 Bromodomain associated SSB PF00436.25 EAU86211.2 - 0.029 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Single-strand binding protein family DUF3632 PF12311.8 EAU86211.2 - 0.13 12.7 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Abhydrolase_6 PF12697.7 EAU86212.1 - 1.6e-18 68.2 0.6 2e-18 67.8 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU86212.1 - 8e-18 65.0 0.1 8.4e-17 61.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAU86212.1 - 1.8e-10 40.5 0.1 5.4e-10 38.9 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EAU86212.1 - 0.043 12.5 0.1 0.059 12.1 0.1 1.1 1 0 0 1 1 1 0 Ndr family Ser_hydrolase PF06821.13 EAU86212.1 - 0.19 11.6 0.1 29 4.5 0.1 2.8 2 1 0 3 3 3 0 Serine hydrolase Glyco_hydro_20 PF00728.22 EAU86214.2 - 1.3e-88 297.8 0.0 1.5e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EAU86214.2 - 4.5e-16 59.7 0.0 9.7e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EAU86214.2 - 0.00088 20.1 0.0 0.0031 18.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_6 PF01341.17 EAU86214.2 - 0.091 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 Glyco_hydro_97 PF10566.9 EAU86214.2 - 0.16 11.2 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 WD40 PF00400.32 EAU86217.2 - 8.6e-06 26.4 0.4 0.00055 20.7 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU86217.2 - 0.002 18.4 0.0 3 8.2 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_C PF00137.21 EAU86220.1 - 5.4e-34 116.3 34.8 6.3e-22 77.7 15.4 2.2 2 0 0 2 2 2 2 ATP synthase subunit C LRR_6 PF13516.6 EAU86222.1 - 4.5e-10 38.7 9.3 0.31 11.2 0.0 7.5 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 EAU86222.1 - 0.43 11.1 18.1 5 7.7 0.1 5.8 4 2 2 7 7 7 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAU86222.1 - 1.7 9.5 8.1 19 6.3 0.1 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat Aldo_ket_red PF00248.21 EAU86225.1 - 2.7e-48 164.6 0.0 2.4e-47 161.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_23 PF13384.6 EAU86225.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r3 PF04539.16 EAU86225.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 Homeodomain PF00046.29 EAU86225.1 - 0.14 12.0 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Homeodomain Methyltransf_25 PF13649.6 EAU86226.2 - 5.3e-17 62.3 0.0 1.2e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU86226.2 - 6e-13 49.3 0.0 1.2e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU86226.2 - 2e-10 40.7 0.0 3.9e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU86226.2 - 5.7e-08 32.7 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU86226.2 - 9.9e-08 31.6 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EAU86226.2 - 3e-06 27.9 0.0 5.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EAU86226.2 - 0.0064 16.0 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 EAU86226.2 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 EAU86226.2 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Rho_N PF07498.12 EAU86227.2 - 0.0032 17.4 0.2 0.0058 16.5 0.2 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.27 EAU86227.2 - 0.028 14.2 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 SAP domain AzlC PF03591.14 EAU86227.2 - 0.17 12.4 0.5 0.35 11.3 0.1 1.6 2 0 0 2 2 2 0 AzlC protein Peptidase_C48 PF02902.19 EAU86228.2 - 3.3e-34 118.6 0.5 5.6e-33 114.6 0.4 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Calpain_III PF01067.22 EAU86228.2 - 0.05 13.9 0.5 8.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Calpain large subunit, domain III Siah-Interact_N PF09032.11 EAU86228.2 - 0.1 12.9 3.2 0.35 11.2 1.5 2.8 2 0 0 2 2 2 0 Siah interacting protein, N terminal Glyco_transf_28 PF03033.20 EAU86229.2 - 2e-24 86.2 0.0 3.8e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EAU86229.2 - 5.3e-06 25.5 0.0 8.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.20 EAU86229.2 - 6.9e-05 22.7 0.1 1.1 9.2 0.0 3.4 3 1 1 4 4 4 2 GRAM domain PH PF00169.29 EAU86229.2 - 0.037 14.5 0.1 0.13 12.8 0.1 2.0 1 0 0 1 1 1 0 PH domain Pkinase_Tyr PF07714.17 EAU86230.2 - 8.5e-09 35.1 0.3 1.2e-07 31.3 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAU86230.2 - 9.2e-09 35.0 0.0 1e-06 28.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Plk4_PB2 PF18409.1 EAU86230.2 - 0.0031 18.2 0.0 0.0081 16.8 0.0 1.7 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 Kinase-like PF14531.6 EAU86230.2 - 0.11 11.8 0.4 7.5 5.8 0.0 2.1 1 1 1 2 2 2 0 Kinase-like Exo_endo_phos PF03372.23 EAU86231.2 - 6.2e-05 22.6 0.1 0.0003 20.4 0.0 2.0 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family PSD3 PF07626.11 EAU86231.2 - 0.082 13.4 0.0 21 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) Spc7 PF08317.11 EAU86233.1 - 0.021 13.7 2.2 0.033 13.1 2.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein CHASE3 PF05227.13 EAU86233.1 - 0.039 13.9 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 CHASE3 domain BLOC1_2 PF10046.9 EAU86233.1 - 0.043 14.1 1.6 0.11 12.8 0.7 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS6_N PF14661.6 EAU86233.1 - 0.045 13.3 0.6 0.069 12.7 0.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RRF PF01765.19 EAU86233.1 - 0.081 12.9 0.6 0.081 12.9 0.6 1.5 2 0 0 2 2 2 0 Ribosome recycling factor DUF1319 PF07028.11 EAU86233.1 - 0.13 12.5 1.8 0.2 11.9 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DHR10 PF18595.1 EAU86233.1 - 0.16 12.0 5.4 0.26 11.3 5.4 1.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 EAU86233.1 - 0.71 10.3 3.1 5.2 7.5 0.4 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) POPLD PF08170.12 EAU86234.2 - 1.5e-34 118.2 0.5 3.1e-34 117.2 0.5 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.11 EAU86234.2 - 4.8e-25 88.8 5.4 9.3e-24 84.6 0.7 2.8 3 0 0 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 GCV_T PF01571.21 EAU86234.2 - 0.055 12.8 0.0 0.91 8.8 0.0 2.5 3 0 0 3 3 3 0 Aminomethyltransferase folate-binding domain Nbl1_Borealin_N PF10444.9 EAU86235.2 - 1.2e-16 60.1 0.6 2.5e-16 59.0 0.1 1.8 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Borealin PF10512.9 EAU86235.2 - 0.0072 16.3 1.0 0.0072 16.3 1.0 4.0 4 1 1 5 5 5 2 Cell division cycle-associated protein 8 3Beta_HSD PF01073.19 EAU86236.1 - 1.8e-68 230.6 0.0 1.4e-61 208.0 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EAU86236.1 - 1e-32 113.5 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAU86236.1 - 2.2e-15 56.9 0.2 1.8e-12 47.3 0.2 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EAU86236.1 - 8.5e-13 48.0 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EAU86236.1 - 2.2e-12 47.3 0.0 3.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EAU86236.1 - 5.2e-11 42.2 0.0 4.4e-09 35.9 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EAU86236.1 - 4.9e-05 22.6 0.6 0.00013 21.3 0.6 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EAU86236.1 - 0.021 14.7 0.1 0.12 12.3 0.0 2.1 1 1 1 2 2 2 0 KR domain NmrA PF05368.13 EAU86236.1 - 0.021 14.4 0.2 0.089 12.3 0.2 1.8 1 1 0 1 1 1 0 NmrA-like family D123 PF07065.14 EAU86237.1 - 3.3e-99 331.9 0.0 3.8e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 EAU86237.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 FA_desaturase PF00487.24 EAU86238.1 - 1.2e-19 71.2 27.6 4e-19 69.4 27.6 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EAU86238.1 - 0.00077 19.7 0.1 0.0016 18.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Pkinase PF00069.25 EAU86239.1 - 1.1e-15 57.7 0.0 1.8e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86239.1 - 3.6e-07 29.7 0.0 2.3e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU86239.1 - 0.0089 14.8 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU86239.1 - 0.036 14.0 0.0 0.14 12.1 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pheromone PF08015.11 EAU86241.2 - 1.6e-05 25.9 1.7 0.00042 21.3 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone TPP_enzyme_N PF02776.18 EAU86242.1 - 1.2e-39 135.6 0.0 1.9e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EAU86242.1 - 9e-16 58.0 0.0 3.6e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAU86242.1 - 2.1e-14 53.4 0.0 1.4e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 EAU86242.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Peptidase_M3 PF01432.20 EAU86243.1 - 5.5e-136 454.5 0.0 7.4e-136 454.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EAU86243.1 - 0.036 13.7 0.2 0.059 13.0 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Usp PF00582.26 EAU86244.2 - 4.5e-21 75.8 0.1 1.5e-20 74.1 0.1 2.0 1 0 0 1 1 1 1 Universal stress protein family IBD PF10416.9 EAU86244.2 - 0.24 11.4 1.0 13 5.8 0.4 2.4 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD Pet127 PF08634.10 EAU86245.2 - 1.5e-109 365.6 0.8 3.8e-109 364.4 0.0 2.0 3 0 0 3 3 3 1 Mitochondrial protein Pet127 Arf PF00025.21 EAU86246.1 - 3.4e-42 143.8 0.0 3.9e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EAU86246.1 - 1.9e-20 73.1 0.0 2.2e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU86246.1 - 2.7e-15 56.7 0.0 4.3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EAU86246.1 - 2e-09 37.1 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAU86246.1 - 3.7e-08 33.0 0.0 4.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU86246.1 - 1.5e-07 31.5 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EAU86246.1 - 9e-06 25.1 0.4 0.00016 20.9 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 EAU86246.1 - 0.00043 20.4 0.4 0.074 13.1 0.4 2.2 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EAU86246.1 - 0.00043 19.9 0.0 0.00093 18.8 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAU86246.1 - 0.0022 17.9 0.0 0.053 13.4 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase DUF751 PF05421.11 EAU86246.1 - 0.0032 18.1 0.8 0.0058 17.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF751) AAA_7 PF12775.7 EAU86246.1 - 0.019 14.5 0.1 0.038 13.5 0.0 1.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EAU86246.1 - 0.064 13.0 0.2 6.7 6.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF2205 PF10224.9 EAU86247.1 - 8.9e-09 35.2 0.7 9.9e-09 35.1 0.7 1.1 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 EAU86247.1 - 0.0045 17.6 1.3 0.005 17.4 1.3 1.1 1 0 0 1 1 1 1 Initiation control protein YabA Bap31_Bap29_C PF18035.1 EAU86247.1 - 0.091 12.8 0.4 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Proteasom_Rpn13 PF04683.13 EAU86248.1 - 3e-26 91.8 0.0 4.4e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EAU86248.1 - 2.9e-25 88.6 0.0 5.4e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 UCH-binding domain zf-Nse PF11789.8 EAU86249.2 - 1.5e-16 59.9 0.0 2.6e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EAU86249.2 - 6.8e-05 23.0 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-C3HC4_2 PF13923.6 EAU86249.2 - 0.00071 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU86249.2 - 0.00092 19.2 0.1 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 RING-type zinc-finger DUF148 PF02520.17 EAU86249.2 - 0.032 14.3 0.7 2.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 zf-C3HC4 PF00097.25 EAU86249.2 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosom_S12_S23 PF00164.25 EAU86250.2 - 5e-32 109.9 1.5 6.7e-32 109.5 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PH_4 PF15404.6 EAU86251.1 - 1.2e-20 74.1 0.2 3.2e-19 69.5 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EAU86251.1 - 0.11 13.0 0.8 0.75 10.3 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain AOX PF01786.17 EAU86252.1 - 7e-96 319.9 0.0 9.4e-96 319.5 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase HTH_Tnp_Tc5 PF03221.16 EAU86253.2 - 7.5e-16 57.9 0.0 1.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EAU86253.2 - 3.8e-06 26.4 0.4 8.6e-06 25.3 0.4 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 EAU86253.2 - 0.00045 19.9 0.8 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 EAU86253.2 - 0.00058 19.3 0.1 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Crp_2 PF13545.6 EAU86253.2 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR_2 PF12802.7 EAU86253.2 - 0.0037 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_37 PF13744.6 EAU86253.2 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 EAU86253.2 - 0.0067 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_10 PF04967.12 EAU86253.2 - 0.0079 16.0 0.2 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 HTH DNA binding domain HTH_Tnp_4 PF13613.6 EAU86253.2 - 0.0097 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_38 PF13936.6 EAU86253.2 - 0.018 14.8 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.6 EAU86253.2 - 0.035 14.2 0.0 0.093 12.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 EAU86253.2 - 0.053 13.4 0.0 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Phage_terminase PF10668.9 EAU86253.2 - 0.059 13.4 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Phage terminase small subunit HTH_3 PF01381.22 EAU86253.2 - 0.075 13.1 0.0 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_26 PF13443.6 EAU86253.2 - 0.12 12.8 0.7 36 4.9 0.0 3.0 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain HTH_24 PF13412.6 EAU86253.2 - 0.15 11.6 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Mga PF05043.13 EAU86253.2 - 0.17 12.5 0.1 0.36 11.5 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain Fungal_trans PF04082.18 EAU86254.2 - 3.9e-05 22.8 0.0 7.8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU86254.2 - 9.5e-05 22.4 9.5 0.0013 18.8 6.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BLM_N PF16202.5 EAU86254.2 - 0.058 12.5 1.1 0.11 11.6 1.1 1.3 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Cucumopine_C PF18631.1 EAU86254.2 - 0.16 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain Tom22 PF04281.13 EAU86255.1 - 2.8e-39 134.0 1.3 3.4e-39 133.8 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NmrA PF05368.13 EAU86256.1 - 9.1e-14 51.6 0.0 1.2e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EAU86256.1 - 4.4e-13 49.3 0.2 4.7e-11 42.6 0.2 3.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAU86256.1 - 4.7e-13 49.4 0.0 8.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EAU86256.1 - 1.8e-11 43.7 0.0 5e-10 39.0 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EAU86256.1 - 2.9e-09 36.3 0.0 1.8e-08 33.8 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAU86256.1 - 1.4e-06 27.9 0.0 1e-05 25.1 0.0 2.0 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EAU86256.1 - 6.2e-05 22.3 0.4 0.43 9.7 0.0 3.0 1 1 1 3 3 3 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 EAU86256.1 - 0.0087 16.3 0.0 0.023 14.9 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EAU86256.1 - 0.056 12.6 0.0 0.13 11.3 0.0 1.6 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein PAP2 PF01569.21 EAU86256.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 PAP2 superfamily DUF2462 PF09495.10 EAU86257.2 - 3.6e-19 69.3 12.8 5.1e-19 68.8 12.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Sas10 PF09368.10 EAU86259.1 - 7.8e-26 90.4 7.7 7.8e-26 90.4 7.7 3.9 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EAU86259.1 - 8.4e-07 29.5 0.6 8.4e-07 29.5 0.6 3.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Fcf2 PF08698.11 EAU86260.1 - 1.6e-28 99.0 0.3 4.9e-28 97.4 0.0 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing SR-25 PF10500.9 EAU86260.1 - 0.00012 21.8 5.0 0.00012 21.8 5.0 1.9 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EAU86260.1 - 0.00014 20.1 11.7 0.00018 19.8 11.7 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Corona_nucleoca PF00937.18 EAU86260.1 - 0.082 11.9 5.8 0.13 11.2 5.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1635 PF07795.11 EAU86260.1 - 0.2 11.5 5.6 0.4 10.5 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DNA_pol_phi PF04931.13 EAU86260.1 - 0.45 8.6 18.8 0.6 8.1 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Menin PF05053.13 EAU86260.1 - 2.3 6.5 6.2 3.3 5.9 6.2 1.1 1 0 0 1 1 1 0 Menin CDC45 PF02724.14 EAU86260.1 - 2.7 6.2 9.4 3.9 5.6 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.6 EAU86260.1 - 3.3 8.9 11.5 7.9 7.6 11.5 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF4661 PF15576.6 EAU86260.1 - 5.5 6.8 8.3 9.1 6.1 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Ubie_methyltran PF01209.18 EAU86261.2 - 2.1e-79 266.1 0.0 1.1e-78 263.8 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EAU86261.2 - 8.5e-14 52.0 0.0 2e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU86261.2 - 6e-12 46.1 0.0 1.2e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU86261.2 - 1.5e-09 37.9 0.0 2.4e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU86261.2 - 4.1e-09 36.4 0.0 7.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU86261.2 - 1e-08 35.8 0.0 1.8e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAU86261.2 - 0.079 12.8 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Cullin PF00888.22 EAU86262.2 - 8.9e-184 612.5 14.6 1.3e-183 612.0 14.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAU86262.2 - 1.8e-26 91.9 1.4 5.8e-26 90.3 1.4 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4980 PF16352.5 EAU86262.2 - 0.012 15.6 0.0 0.043 13.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4980) Phage_rep_O PF04492.13 EAU86262.2 - 0.019 15.5 0.3 0.069 13.7 0.1 2.1 1 1 1 2 2 2 0 Bacteriophage replication protein O Rrf2 PF02082.20 EAU86262.2 - 0.031 14.6 0.1 0.3 11.5 0.1 2.5 3 0 0 3 3 3 0 Transcriptional regulator HTH_27 PF13463.6 EAU86262.2 - 0.13 12.8 0.5 24 5.5 0.1 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain HAT_KAT11 PF08214.11 EAU86263.1 - 1.9e-47 162.2 0.0 2.6e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein BshC PF10079.9 EAU86264.2 - 0.15 10.8 0.3 0.21 10.3 0.3 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF3915 PF13054.6 EAU86264.2 - 8.7 6.3 8.0 19 5.2 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Peptidase_S28 PF05577.12 EAU86268.2 - 1.3e-55 188.9 0.0 3.3e-45 154.7 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 BHD_1 PF10403.9 EAU86269.2 - 3.5e-21 74.8 0.1 1.3e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 EAU86269.2 - 6.7e-21 74.5 1.0 6.7e-21 74.5 1.0 3.5 3 1 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 EAU86269.2 - 3.2e-15 56.8 0.0 3.2e-15 56.8 0.0 5.0 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EAU86269.2 - 2.8e-07 31.0 0.0 6.6e-06 26.5 0.0 2.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF3134 PF11332.8 EAU86269.2 - 1.4 9.3 0.0 1.4 9.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) GCD14 PF08704.10 EAU86270.1 - 7.3e-94 314.0 0.1 1.2e-91 306.8 0.1 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EAU86270.1 - 1.1e-05 25.3 0.0 3.1e-05 23.8 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EAU86270.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 EAU86270.1 - 0.013 15.4 0.0 0.059 13.2 0.0 2.0 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term Fibrillarin PF01269.17 EAU86270.1 - 0.032 13.3 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin Gcd10p PF04189.13 EAU86270.1 - 0.045 12.9 4.9 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Gcd10p family Peptidase_C37 PF05416.12 EAU86270.1 - 0.085 11.4 0.4 0.12 10.8 0.4 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase zf-RING_2 PF13639.6 EAU86271.2 - 3.8e-08 33.5 3.9 1.1e-07 32.1 1.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EAU86271.2 - 1.1e-07 32.0 2.3 2.1e-07 31.1 2.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EAU86271.2 - 1.2e-05 25.1 2.3 2.2e-05 24.3 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EAU86271.2 - 2.1e-05 24.0 0.4 4.1e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EAU86271.2 - 5.1e-05 23.0 5.6 0.00012 21.8 3.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU86271.2 - 5.2e-05 23.1 1.2 8.5e-05 22.4 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU86271.2 - 5.4e-05 23.1 2.3 0.00017 21.5 2.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EAU86271.2 - 0.00089 19.0 1.6 0.0029 17.3 0.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 EAU86271.2 - 0.0015 18.3 1.1 0.0015 18.3 1.1 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EAU86271.2 - 0.0022 18.0 0.2 0.004 17.2 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EAU86271.2 - 0.0037 17.1 2.7 0.0044 16.9 0.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EAU86271.2 - 0.049 13.8 1.0 0.095 12.8 1.0 1.4 1 0 0 1 1 1 0 RING-variant domain Rtf2 PF04641.12 EAU86271.2 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING-like PF08746.11 EAU86271.2 - 0.21 11.9 2.0 0.36 11.2 2.0 1.3 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 EAU86271.2 - 0.21 11.8 4.1 0.068 13.3 0.9 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EAU86271.2 - 0.22 11.7 0.7 0.48 10.7 0.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EAU86271.2 - 2.3 8.3 5.2 5.3 7.2 5.2 1.6 1 1 0 1 1 1 0 Zinc-finger Nop PF01798.18 EAU86275.1 - 9.2e-86 287.0 0.0 9.2e-86 287.0 0.0 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EAU86275.1 - 3.5e-22 78.5 0.2 3.5e-22 78.5 0.2 2.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain HEAT_2 PF13646.6 EAU86276.1 - 3.6e-06 27.3 1.2 0.65 10.4 0.0 4.5 4 0 0 4 4 4 2 HEAT repeats IBN_N PF03810.19 EAU86276.1 - 2.3e-05 24.2 0.0 0.00021 21.1 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EAU86276.1 - 0.00078 18.1 3.0 0.0097 14.5 1.3 2.6 2 0 0 2 2 2 1 Adaptin N terminal region Xpo1 PF08389.12 EAU86276.1 - 0.0028 17.7 3.2 0.025 14.7 0.0 3.8 3 1 0 3 3 3 1 Exportin 1-like protein Cnd1 PF12717.7 EAU86276.1 - 0.0064 16.5 2.2 1.4 8.9 0.4 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cse1 PF08506.10 EAU86276.1 - 0.0065 15.3 0.9 0.017 14.0 0.0 2.3 2 1 0 2 2 2 1 Cse1 HEAT_EZ PF13513.6 EAU86276.1 - 0.03 14.8 0.2 3.9 8.1 0.0 4.2 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 EAU86276.1 - 0.097 13.0 0.1 11 6.6 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Actin PF00022.19 EAU86278.2 - 3e-82 276.4 0.0 3.1e-81 273.1 0.0 1.9 1 1 0 1 1 1 1 Actin TANGO2 PF05742.12 EAU86279.2 - 1.8e-48 165.8 0.0 2.1e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Zn_clus PF00172.18 EAU86280.1 - 1.6e-08 34.5 7.2 3.4e-08 33.5 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 EAU86280.1 - 0.03 14.2 0.9 1.2 9.1 0.4 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PSS PF03034.15 EAU86281.1 - 8.7e-117 389.7 10.4 1.1e-116 389.3 10.4 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase PET PF06297.14 EAU86281.1 - 0.014 15.6 0.0 0.041 14.2 0.0 1.7 2 0 0 2 2 2 0 PET Domain Kin17_mid PF10357.9 EAU86282.1 - 4.6e-51 172.0 0.7 1e-50 170.9 0.7 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EAU86282.1 - 0.00019 21.7 6.4 0.00041 20.6 6.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAU86282.1 - 0.00078 19.7 5.0 0.0017 18.6 5.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EAU86282.1 - 0.013 15.8 4.2 0.014 15.7 1.2 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Cellulase PF00150.18 EAU86284.2 - 1.4e-05 24.7 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.7 EAU86285.2 - 0.0001 22.1 0.3 0.00026 20.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like DUF1326 PF07040.11 EAU86285.2 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) F-box-like PF12937.7 EAU86286.2 - 1.8e-10 40.5 0.4 3.8e-10 39.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86286.2 - 1.3e-05 24.9 0.6 0.0001 22.0 0.2 2.5 2 0 0 2 2 2 1 F-box domain AMP-binding PF00501.28 EAU86288.2 - 3.6e-71 240.0 0.0 4.9e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU86288.2 - 4.7e-08 33.9 0.0 1.2e-07 32.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-MYND PF01753.18 EAU86289.2 - 2.9e-07 30.5 11.9 5.5e-07 29.6 11.9 1.4 1 0 0 1 1 1 1 MYND finger CRAL_TRIO_2 PF13716.6 EAU86290.2 - 3.6e-32 111.4 0.2 6e-32 110.7 0.2 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 EAU86290.2 - 3.4e-31 108.1 0.0 5.6e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 EAU86290.2 - 2.1e-05 24.3 0.1 7.3e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain Hist_deacetyl PF00850.19 EAU86292.2 - 1.9e-47 162.3 0.9 2.3e-47 162.0 0.9 1.2 1 0 0 1 1 1 1 Histone deacetylase domain EF-1_beta_acid PF10587.9 EAU86295.1 - 0.0034 17.8 1.7 0.0034 17.8 1.7 3.5 5 0 0 5 5 5 1 Eukaryotic elongation factor 1 beta central acidic region Cor1 PF04803.12 EAU86295.1 - 0.034 14.4 6.5 1.1 9.4 6.5 2.4 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region GAT PF03127.14 EAU86295.1 - 0.049 13.9 2.6 4.4 7.7 0.3 2.7 1 1 1 2 2 2 0 GAT domain Herpes_UL6 PF01763.16 EAU86295.1 - 0.056 12.0 0.9 0.068 11.7 0.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF2239 PF09998.9 EAU86295.1 - 0.067 13.0 1.0 7.5 6.3 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF1848 PF08902.11 EAU86295.1 - 0.13 11.9 1.1 0.17 11.6 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1848) TetR_C_23 PF17931.1 EAU86295.1 - 0.88 9.7 6.1 0.81 9.8 0.2 2.6 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Gluconate_2-dh3 PF13618.6 EAU86295.1 - 6.2 7.1 6.7 11 6.2 6.7 1.7 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF3552 PF12072.8 EAU86297.2 - 0.0012 18.4 9.3 0.0012 18.4 9.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Exonuc_VII_L PF02601.15 EAU86297.2 - 0.0023 17.6 3.2 0.0023 17.6 3.2 1.5 2 0 0 2 2 2 1 Exonuclease VII, large subunit VHS PF00790.19 EAU86297.2 - 0.047 13.5 1.6 0.052 13.4 0.2 1.7 2 0 0 2 2 2 0 VHS domain Atg14 PF10186.9 EAU86297.2 - 6.3 5.8 14.7 0.2 10.7 8.3 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 F-box-like PF12937.7 EAU86298.2 - 0.0014 18.4 0.5 0.0063 16.4 0.1 2.2 2 0 0 2 2 2 1 F-box-like Ski_Sno PF02437.17 EAU86298.2 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 SKI/SNO/DAC family Mito_carr PF00153.27 EAU86299.1 - 1.6e-59 197.8 6.6 2.9e-20 72.0 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EAU86299.1 - 3.3e-05 23.2 1.1 0.045 12.9 0.1 2.9 2 1 2 4 4 4 2 Gammaproteobacterial serine protease tRNA_int_end_N2 PF12928.7 EAU86300.1 - 3.5e-22 78.3 0.0 6.3e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EAU86300.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Asp PF00026.23 EAU86301.1 - 2.1e-28 99.6 0.0 3.3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU86301.1 - 1.7e-07 31.6 0.2 7.4e-05 23.1 0.5 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAU86301.1 - 0.0032 18.1 0.1 0.15 12.7 0.0 2.7 2 1 0 2 2 2 1 Aspartyl protease p450 PF00067.22 EAU86303.2 - 3.6e-29 101.8 0.0 5.2e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_10 PF13374.6 EAU86304.2 - 7.7e-32 108.3 1.3 2.8e-05 23.8 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat CHAT PF12770.7 EAU86304.2 - 1.1e-25 90.7 0.0 2.3e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU86304.2 - 1.7e-05 25.0 4.8 16 5.9 0.0 7.7 8 1 2 10 10 10 2 Tetratricopeptide repeat DUF3037 PF11236.8 EAU86304.2 - 0.097 13.1 0.4 14 6.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3037) Amino_oxidase PF01593.24 EAU86305.1 - 1.3e-20 74.1 0.0 1e-17 64.6 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAU86305.1 - 2.1e-13 50.3 0.0 8e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU86305.1 - 3.1e-05 23.7 0.3 0.0015 18.2 0.0 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAU86305.1 - 0.00086 19.3 0.0 0.43 10.6 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAU86305.1 - 0.0097 15.2 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1918 PF08940.11 EAU86305.1 - 0.044 13.4 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Thi4 PF01946.17 EAU86305.1 - 0.052 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_4 PF01565.23 EAU86306.2 - 1.5e-14 53.9 0.1 3.6e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU86306.2 - 1.7e-10 40.8 0.8 4.6e-10 39.4 0.8 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EAU86306.2 - 0.011 15.1 0.2 0.016 14.6 0.2 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Toxin_10 PF05431.11 EAU86306.2 - 0.082 12.4 0.2 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 DcpS PF05652.12 EAU86307.2 - 4.2e-28 98.2 0.0 7.7e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EAU86307.2 - 8.5e-19 68.1 1.0 2.9e-18 66.4 1.0 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GlutR_dimer PF00745.20 EAU86307.2 - 0.042 14.3 0.1 0.095 13.2 0.1 1.6 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain POPLD PF08170.12 EAU86308.2 - 0.48 10.8 3.7 1.1 9.6 3.7 1.6 1 0 0 1 1 1 0 POPLD (NUC188) domain NPR3 PF03666.13 EAU86308.2 - 0.97 8.1 5.8 1.4 7.6 5.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Spt20 PF12090.8 EAU86308.2 - 1.1 8.8 6.2 1.1 8.9 4.0 1.9 2 0 0 2 2 2 0 Spt20 family XPG_I PF00867.18 EAU86309.2 - 1.7e-29 102.0 0.0 5.5e-29 100.4 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EAU86309.2 - 1.8e-19 70.1 0.0 4.6e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EAU86309.2 - 2.9e-07 31.0 0.0 9.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF913 PF06025.12 EAU86309.2 - 2.1 7.2 5.5 3.8 6.4 5.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF565 PF04483.12 EAU86311.2 - 0.46 11.1 6.3 1.1 9.8 5.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF565) SAYSvFN PF10260.9 EAU86311.2 - 0.67 9.9 0.0 0.67 9.9 0.0 3.0 4 0 0 4 4 4 0 Uncharacterized conserved domain (SAYSvFN) FAD_binding_4 PF01565.23 EAU86312.2 - 2.5e-17 62.9 3.7 2.2e-10 40.4 1.6 2.9 2 1 1 3 3 3 2 FAD binding domain BBE PF08031.12 EAU86312.2 - 6.1e-09 35.8 0.3 1.4e-08 34.7 0.3 1.6 1 0 0 1 1 1 1 Berberine and berberine like VHS PF00790.19 EAU86313.2 - 2.8e-07 30.5 0.4 4.8e-07 29.7 0.4 1.3 1 0 0 1 1 1 1 VHS domain DUF3552 PF12072.8 EAU86313.2 - 0.006 16.0 12.5 0.011 15.1 12.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) 5_nucleotid PF05761.14 EAU86313.2 - 1.6 7.5 7.0 0.84 8.5 4.6 1.6 2 0 0 2 2 2 0 5' nucleotidase family Exonuc_VII_L PF02601.15 EAU86313.2 - 4.4 6.8 6.0 0.65 9.5 2.0 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit p450 PF00067.22 EAU86314.2 - 8.8e-47 159.9 0.0 2.3e-24 86.0 0.1 2.4 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EAU86315.2 - 2e-56 191.7 0.1 3.4e-29 101.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 FolB PF02152.18 EAU86317.2 - 0.054 14.1 0.0 0.083 13.4 0.0 1.2 1 0 0 1 1 1 0 Dihydroneopterin aldolase BTB PF00651.31 EAU86319.2 - 0.031 14.5 0.0 0.081 13.2 0.0 1.7 1 1 1 2 2 2 0 BTB/POZ domain 2OG-FeII_Oxy_3 PF13640.6 EAU86321.1 - 8.4e-14 52.2 0.0 2.2e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EAU86321.1 - 0.012 14.8 0.0 0.018 14.1 0.0 1.4 1 1 0 1 1 1 0 Poxvirus C4/C10 protein 2OG-FeII_Oxy PF03171.20 EAU86321.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Sen15 PF09631.10 EAU86322.2 - 1.8e-16 60.2 0.0 2.4e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein NAD_binding_10 PF13460.6 EAU86323.1 - 8.5e-08 32.3 0.0 1e-06 28.8 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAU86323.1 - 3.6e-05 23.4 0.0 0.00012 21.8 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EAU86323.1 - 0.16 11.4 0.0 1 8.8 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Tyrosinase PF00264.20 EAU86324.1 - 1.1e-39 137.0 0.0 1.8e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF4349 PF14257.6 EAU86325.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) F-box-like PF12937.7 EAU86328.2 - 3.2e-12 46.1 0.4 1.2e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU86328.2 - 0.0012 18.7 0.0 0.0044 16.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain Abhydrolase_3 PF07859.13 EAU86329.2 - 1.3e-14 54.5 0.0 1.9e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU86329.2 - 2.2e-10 40.4 0.0 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EAU86329.2 - 0.00054 19.7 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EAU86329.2 - 0.0062 16.1 0.0 0.089 12.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EAU86329.2 - 0.077 12.8 0.0 0.78 9.5 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FYRN PF05964.14 EAU86330.1 - 1.6e-18 66.3 1.2 3.7e-18 65.1 1.2 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EAU86330.1 - 2e-17 63.1 0.0 5.8e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 F/Y rich C-terminus Laminin_II PF06009.12 EAU86330.1 - 0.055 13.5 1.5 0.13 12.3 1.5 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF573 PF04504.14 EAU86330.1 - 0.1 13.3 1.2 0.27 11.9 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF573 DUF3450 PF11932.8 EAU86330.1 - 0.1 11.9 4.6 0.17 11.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) GAS PF13851.6 EAU86330.1 - 0.31 10.4 4.7 0.53 9.6 4.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 EAU86330.1 - 0.41 11.1 5.0 0.84 10.1 5.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB OmpH PF03938.14 EAU86330.1 - 6.8 7.0 8.7 12 6.2 8.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SIR2 PF02146.17 EAU86331.2 - 1.2e-60 204.5 0.0 1.6e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-LYAR PF08790.11 EAU86331.2 - 0.087 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger TRAF6_Z2 PF18048.1 EAU86331.2 - 0.14 12.2 0.2 0.27 11.3 0.2 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 DUF2721 PF11026.8 EAU86333.1 - 7.7 6.4 16.7 1.9 8.4 1.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) Prog_receptor PF02161.15 EAU86334.1 - 0.12 11.0 2.3 0.16 10.7 2.3 1.1 1 0 0 1 1 1 0 Progesterone receptor Gypsy PF07253.11 EAU86335.1 - 0.091 11.3 0.1 0.15 10.6 0.1 1.2 1 0 0 1 1 1 0 Gypsy protein DUF2721 PF11026.8 EAU86335.1 - 0.091 12.6 12.2 0.68 9.8 2.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DUF565 PF04483.12 EAU86336.2 - 0.04 14.4 0.2 0.12 13.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF565) TraP PF07296.11 EAU86336.2 - 0.13 11.4 2.5 7.7 5.6 0.0 2.3 2 0 0 2 2 2 0 TraP protein FAD-oxidase_C PF02913.19 EAU86338.2 - 1.4e-57 195.2 0.0 2e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EAU86338.2 - 2.5e-15 56.4 0.0 9.3e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain HAMP PF00672.25 EAU86338.2 - 0.14 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 HAMP domain Putative_PNPOx PF01243.20 EAU86339.1 - 1.7e-05 24.9 0.1 0.0026 17.9 0.0 3.9 4 1 0 4 4 4 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 EAU86339.1 - 0.0001 22.6 0.0 0.081 13.3 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EAU86339.1 - 0.0041 17.7 0.0 0.083 13.5 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EAU86339.1 - 0.005 17.0 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PQ-loop PF04193.14 EAU86340.1 - 1.2e-24 85.8 3.4 3.2e-12 46.0 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EAU86340.1 - 0.072 13.9 2.3 0.12 13.2 2.3 1.3 1 0 0 1 1 1 0 ER lumen protein retaining receptor DUF4203 PF13886.6 EAU86340.1 - 0.19 11.3 7.7 0.29 10.8 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4203) DUF1361 PF07099.11 EAU86341.2 - 0.0033 17.4 9.9 0.0065 16.5 2.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1361) Tmemb_170 PF10190.9 EAU86341.2 - 0.0041 17.5 4.7 0.0041 17.5 4.7 2.0 2 0 0 2 2 2 1 Putative transmembrane protein 170 IBV_3C PF03620.13 EAU86341.2 - 0.4 11.2 2.4 0.34 11.4 0.4 1.9 2 0 0 2 2 2 0 IBV 3C protein ABC_trans_CmpB PF06541.11 EAU86341.2 - 1.3 9.3 8.6 0.78 10.0 6.5 1.7 2 0 0 2 2 2 0 Putative ABC-transporter type IV DUF3270 PF11674.8 EAU86341.2 - 1.9 8.7 5.0 2.3 8.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Abhydrolase_9_N PF15420.6 EAU86343.2 - 0.047 13.7 7.0 0.091 12.8 7.0 1.6 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SHR3_chaperone PF08229.11 EAU86343.2 - 0.16 11.0 4.5 0.4 9.6 0.1 2.7 2 1 1 3 3 3 0 ER membrane protein SH3 DUF2721 PF11026.8 EAU86343.2 - 6.3 6.7 17.5 1.5 8.7 1.9 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) Hom_end PF05204.14 EAU86345.2 - 0.038 14.2 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 Homing endonuclease PRP1_N PF06424.12 EAU86347.2 - 1.1e-47 162.1 4.5 1.1e-47 162.1 4.5 2.8 2 1 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EAU86347.2 - 5.8e-22 76.5 37.1 0.0005 20.7 0.5 13.8 7 4 8 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 EAU86347.2 - 2.5e-13 50.3 15.7 0.018 15.5 0.4 8.6 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EAU86347.2 - 1.3e-11 45.0 13.8 0.013 16.1 0.0 7.3 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAU86347.2 - 1.4e-06 28.5 5.3 1.8 9.4 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU86347.2 - 0.00011 22.3 1.0 15 6.3 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.9 EAU86347.2 - 0.015 15.0 2.1 0.11 12.2 0.5 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 EAU86347.2 - 0.057 13.6 11.1 0.31 11.2 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EAU86347.2 - 0.27 11.2 0.9 53 3.7 0.0 3.9 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal FAT PF02259.23 EAU86347.2 - 0.43 9.7 7.2 0.44 9.7 0.3 3.9 3 1 0 4 4 4 0 FAT domain Pkinase PF00069.25 EAU86349.1 - 0.051 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86349.1 - 0.25 10.6 0.0 0.39 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 EAU86350.1 - 3.7e-12 46.7 0.0 0.00016 21.7 0.0 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family GDA1_CD39 PF01150.17 EAU86353.2 - 7.1e-90 301.7 0.0 1.1e-89 301.0 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF1996 PF09362.10 EAU86359.2 - 8.8e-62 209.2 0.4 1.1e-61 208.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SH3_1 PF00018.28 EAU86360.1 - 3.6e-06 26.5 0.1 1.2e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EAU86360.1 - 0.00016 21.5 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU86360.1 - 0.00029 20.5 0.0 0.00067 19.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Cadherin_C_2 PF16492.5 EAU86360.1 - 0.019 15.7 0.0 0.055 14.2 0.0 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal MAP17 PF15807.5 EAU86360.1 - 0.091 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PAP2 PF01569.21 EAU86361.2 - 0.00078 19.2 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily Polysacc_lyase PF14099.6 EAU86362.2 - 0.00014 21.8 0.0 0.00031 20.7 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide lyase Na_H_Exchanger PF00999.21 EAU86363.2 - 6.9e-52 176.5 21.6 1e-51 176.0 21.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sbt_1 PF05982.12 EAU86363.2 - 0.016 14.5 5.8 1.1 8.5 1.0 3.1 3 0 0 3 3 3 0 Na+-dependent bicarbonate transporter superfamily Collagen_mid PF15984.5 EAU86364.2 - 0.028 14.2 0.0 0.032 14.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial collagen, middle region Peptidase_M36 PF02128.15 EAU86365.2 - 2.3e-122 408.7 0.2 2.8e-122 408.5 0.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EAU86365.2 - 4.3e-08 32.9 1.2 1e-07 31.7 1.2 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EAU86365.2 - 0.046 14.3 0.0 0.16 12.6 0.0 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF1202 PF06717.11 EAU86365.2 - 0.2 11.1 0.1 0.31 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF2235 PF09994.9 EAU86367.2 - 2.1e-65 221.0 0.8 3.4e-64 217.0 0.8 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 EAU86367.2 - 0.0062 16.5 0.0 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EAU86367.2 - 0.01 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EAU86367.2 - 0.023 14.5 0.0 0.064 13.1 0.0 1.7 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF2235 PF09994.9 EAU86368.1 - 0.00044 19.7 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 EAU86369.2 - 1.6e-95 319.8 0.1 2.2e-95 319.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4699 PF15770.5 EAU86369.2 - 0.027 14.3 1.7 0.046 13.5 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) BAAT_C PF08840.11 EAU86369.2 - 0.1 12.5 0.0 0.73 9.7 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal MRI PF15325.6 EAU86369.2 - 0.1 13.7 5.4 8.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection F-box-like PF12937.7 EAU86370.2 - 4.5e-06 26.5 1.9 8.6e-06 25.6 1.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86370.2 - 1.6e-05 24.7 3.6 4e-05 23.4 3.6 1.8 1 0 0 1 1 1 1 F-box domain PhnG PF06754.12 EAU86373.1 - 0.099 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Kinesin PF00225.23 EAU86378.2 - 2.4e-91 306.1 0.0 3e-90 302.5 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAU86378.2 - 2.5e-22 79.4 0.0 6.7e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Med2 PF11214.8 EAU86378.2 - 0.0015 18.6 0.6 0.006 16.7 0.6 2.0 1 0 0 1 1 1 1 Mediator complex subunit 2 Pox_A_type_inc PF04508.12 EAU86378.2 - 0.04 13.8 3.2 0.13 12.1 1.9 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat BNIP2 PF12496.8 EAU86378.2 - 2.1 8.8 8.0 2.2 8.7 5.2 2.5 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SlyX PF04102.12 EAU86378.2 - 5.9 7.6 13.8 16 6.2 0.6 4.6 3 2 1 4 4 4 0 SlyX DUF3734 PF12536.8 EAU86380.1 - 0.011 16.1 8.6 0.54 10.6 1.8 2.2 2 0 0 2 2 2 0 Patatin phospholipase Atg14 PF10186.9 EAU86380.1 - 0.038 13.1 15.7 0.045 12.8 15.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EAU86380.1 - 0.05 13.2 9.1 0.055 13.0 9.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sfi1_C PF10638.9 EAU86380.1 - 1.1 10.1 10.6 1.5 9.6 4.5 2.7 1 1 2 3 3 3 0 Spindle body associated protein C-terminus Tho2 PF11262.8 EAU86380.1 - 1.5 8.0 9.1 2.1 7.5 9.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 HMMR_C PF15908.5 EAU86380.1 - 1.6 8.9 18.6 1.4 9.1 10.8 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal AAA_13 PF13166.6 EAU86380.1 - 1.9 7.0 18.0 2.3 6.7 18.0 1.0 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 EAU86380.1 - 2.1 7.1 18.6 2.8 6.7 18.1 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EAU86380.1 - 2.2 7.6 13.0 2.7 7.3 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EAU86380.1 - 2.5 8.3 12.6 0.39 10.9 6.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Borrelia_P83 PF05262.11 EAU86380.1 - 3.8 5.9 25.5 4.6 5.6 25.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein G-gamma PF00631.22 EAU86380.1 - 7.2 6.7 12.2 0.88 9.6 4.8 2.6 1 1 2 3 3 3 0 GGL domain TMF_DNA_bd PF12329.8 EAU86380.1 - 8.1 6.5 25.1 0.63 10.1 18.7 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 EAU86380.1 - 8.5 6.8 24.0 7.4 7.0 6.2 2.0 1 1 1 2 2 2 0 Fez1 Csm1_N PF18504.1 EAU86380.1 - 8.7 6.8 18.9 9.4 6.7 8.7 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain ketoacyl-synt PF00109.26 EAU86383.2 - 1.5e-70 237.7 0.1 2.3e-70 237.0 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EAU86383.2 - 2.2e-43 149.0 0.0 3.5e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EAU86383.2 - 5.9e-35 119.8 1.1 1.5e-34 118.5 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 EAU86383.2 - 1.3e-21 77.1 0.4 3.1e-21 75.9 0.4 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 EAU86383.2 - 3.3e-09 37.0 0.0 7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.20 EAU86383.2 - 1.2e-08 35.4 0.0 1.2e-06 28.8 0.0 2.8 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_6 PF12697.7 EAU86383.2 - 3.8e-05 24.4 1.5 0.12 13.0 0.0 3.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.23 EAU86383.2 - 0.00033 20.1 0.6 0.0006 19.3 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EAU86383.2 - 0.011 16.2 0.0 0.036 14.5 0.0 1.9 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Defb50 PF17546.2 EAU86385.1 - 0.048 13.6 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Beta defensin 50 adh_short PF00106.25 EAU86386.2 - 7.6e-34 116.9 0.9 1e-33 116.4 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86386.2 - 1.5e-13 50.8 0.8 2e-13 50.5 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU86386.2 - 2.7e-09 37.2 0.1 4.1e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EAU86386.2 - 0.043 13.6 0.3 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 EAU86387.2 - 1.5e-32 112.7 0.1 1.9e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86387.2 - 7e-11 42.1 0.0 8.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU86387.2 - 2.4e-07 30.8 0.0 3.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EAU86387.2 - 0.044 13.5 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_61 PF03443.14 EAU86388.2 - 2e-50 171.6 0.0 2.6e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 EAU86389.1 - 7.9e-49 166.4 0.0 1e-48 166.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 tRNA_bind PF01588.20 EAU86389.1 - 0.069 13.3 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative tRNA binding domain GST_C_2 PF13410.6 EAU86390.2 - 0.0032 17.5 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU86390.2 - 0.011 15.9 0.2 0.024 14.8 0.2 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Clathrin-link PF09268.10 EAU86390.2 - 0.12 11.8 0.4 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 Clathrin, heavy-chain linker SH3_1 PF00018.28 EAU86392.1 - 1.5e-11 43.7 0.1 2.3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAU86392.1 - 3.3e-10 39.5 0.0 5.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EAU86392.1 - 1e-09 38.1 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MASE3 PF17159.4 EAU86392.1 - 0.027 14.1 4.9 0.038 13.6 4.9 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain DUF2165 PF09933.9 EAU86392.1 - 0.04 14.0 2.5 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DUF2569 PF10754.9 EAU86392.1 - 0.81 10.1 8.3 2.1 8.8 8.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DAO PF01266.24 EAU86393.2 - 8.8e-52 176.8 0.1 1.5e-51 176.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EAU86393.2 - 1.7e-44 150.7 0.1 3.4e-44 149.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EAU86393.2 - 7.8e-08 31.8 2.4 6.6e-07 28.7 2.4 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EAU86393.2 - 0.00017 21.0 0.2 0.00029 20.3 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU86393.2 - 0.0034 16.7 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU86393.2 - 0.0064 16.7 0.7 0.017 15.3 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU86393.2 - 0.0065 15.6 0.2 1.2 8.1 0.8 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EAU86393.2 - 0.019 13.7 1.4 0.029 13.1 1.4 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EAU86393.2 - 0.026 13.6 0.9 0.054 12.6 0.2 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EAU86393.2 - 0.18 11.7 0.3 0.31 10.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EAU86393.2 - 0.42 9.8 1.7 0.69 9.1 0.8 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU86393.2 - 4.9 6.3 5.5 0.96 8.6 0.3 2.0 2 0 0 2 2 2 0 Thi4 family BNR_4 PF15892.5 EAU86395.1 - 1.7e-80 270.3 0.5 2.3e-80 269.9 0.5 1.2 1 0 0 1 1 1 1 BNR repeat-containing family member BNR PF02012.20 EAU86395.1 - 0.097 12.7 1.5 0.33 11.1 0.2 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat WW PF00397.26 EAU86397.1 - 1.4e-23 82.7 28.8 6.4e-05 23.0 0.1 6.7 6 0 0 6 6 6 6 WW domain PQQ_2 PF13360.6 EAU86397.1 - 0.12 12.0 0.3 0.6 9.6 0.0 2.2 2 2 0 2 2 2 0 PQQ-like domain RRM_1 PF00076.22 EAU86400.2 - 1.3e-09 37.7 1.1 0.00054 19.7 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 EAU86401.2 - 1.5e-21 76.8 4.6 6.4e-20 71.4 0.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAU86401.2 - 6.1e-17 61.6 25.6 4.3e-13 48.9 12.8 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Strabismus PF06638.11 EAU86401.2 - 0.04 12.6 0.6 0.091 11.4 0.6 1.5 1 0 0 1 1 1 0 Strabismus protein Pantoate_transf PF02548.15 EAU86404.1 - 1.5e-105 352.3 0.0 1.8e-105 352.0 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EAU86404.1 - 1.1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ribonuc_L-PSP PF01042.21 EAU86405.2 - 4.5e-19 68.6 0.0 5.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP F-box PF00646.33 EAU86408.2 - 1.9e-07 30.8 6.4 4.8e-07 29.5 6.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU86408.2 - 7.4e-06 25.8 3.0 7.4e-06 25.8 3.0 2.1 2 0 0 2 2 2 1 F-box-like NACHT PF05729.12 EAU86409.2 - 1.1e-07 32.0 0.0 1.3e-06 28.4 0.0 2.7 2 1 1 3 3 3 1 NACHT domain AAA_16 PF13191.6 EAU86409.2 - 1.3e-07 32.1 1.0 4.5e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU86409.2 - 0.00015 22.0 0.0 0.001 19.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU86409.2 - 0.0017 18.1 0.2 0.0034 17.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAU86409.2 - 0.041 14.4 0.1 0.67 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EAU86409.2 - 0.046 13.7 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EAU86409.2 - 0.091 11.9 0.2 0.2 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SSE PF00437.20 EAU86409.2 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein YjeJ PF15922.5 EAU86409.2 - 0.11 11.6 1.3 0.27 10.4 0.9 1.7 2 0 0 2 2 2 0 YjeJ-like NTPase_1 PF03266.15 EAU86409.2 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 EAU86409.2 - 0.16 11.1 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 EAU86409.2 - 0.44 10.1 3.4 0.2 11.2 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M43 PF05572.13 EAU86410.2 - 2.4e-17 63.2 0.0 4e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU86410.2 - 0.00044 20.5 0.1 0.00071 19.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAU86410.2 - 0.0024 17.5 0.3 0.0048 16.6 0.3 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EAU86410.2 - 0.026 13.5 0.6 0.041 12.8 0.6 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.6 EAU86410.2 - 0.13 12.8 0.3 0.22 12.1 0.3 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EAU86410.2 - 0.19 10.9 0.2 0.31 10.2 0.2 1.2 1 0 0 1 1 1 0 Met-zincin RTA1 PF04479.13 EAU86411.2 - 4.4e-63 212.6 7.7 4.4e-63 212.6 7.7 1.6 2 0 0 2 2 2 1 RTA1 like protein DUF2070 PF09843.9 EAU86411.2 - 6.4 4.9 8.4 17 3.6 8.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) bZIP_1 PF00170.21 EAU86412.1 - 3.4e-06 27.0 8.4 7.4e-06 26.0 8.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAU86412.1 - 3.9e-06 26.8 8.7 3.9e-06 26.8 8.7 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EAU86412.1 - 1 9.9 10.4 0.92 10.1 8.8 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor p450 PF00067.22 EAU86414.2 - 1.6e-49 168.9 1.7 1.7e-26 93.0 0.1 2.0 1 1 0 2 2 2 2 Cytochrome P450 DUF1033 PF06279.11 EAU86414.2 - 0.13 12.4 0.1 5.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) p450 PF00067.22 EAU86415.2 - 2.8e-63 214.3 0.0 4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SMC_N PF02463.19 EAU86418.1 - 4.1e-16 59.1 31.8 1.8e-15 57.0 29.2 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EAU86418.1 - 2.4e-14 54.3 17.2 2.4e-14 54.3 17.2 6.2 3 2 1 4 4 2 1 AAA domain AAA_15 PF13175.6 EAU86418.1 - 7.6e-12 45.6 16.0 7.6e-12 45.6 16.0 3.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 EAU86418.1 - 1.1e-05 25.4 1.4 0.0032 17.3 0.1 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAU86418.1 - 0.00082 19.1 0.0 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 EAU86418.1 - 0.001 18.0 89.8 0.0019 17.2 11.9 5.1 3 1 3 6 6 6 4 Spc7 kinetochore protein AAA_13 PF13166.6 EAU86418.1 - 0.0023 16.6 25.0 0.0023 16.6 25.0 5.4 3 2 3 6 6 6 2 AAA domain MscS_porin PF12795.7 EAU86418.1 - 0.0026 17.3 3.9 0.0026 17.3 3.9 5.3 3 2 1 4 4 4 3 Mechanosensitive ion channel porin domain GAS PF13851.6 EAU86418.1 - 0.0035 16.7 98.7 0.028 13.8 18.0 5.8 2 2 1 4 4 4 3 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.19 EAU86418.1 - 0.56 7.9 91.2 0.023 12.5 39.6 3.6 2 1 1 3 3 3 0 Myosin tail DUF1664 PF07889.12 EAU86418.1 - 4.4 7.4 50.5 3.6 7.7 0.3 7.8 4 2 4 8 8 8 0 Protein of unknown function (DUF1664) Cellulase PF00150.18 EAU86419.2 - 2.8e-11 43.4 0.0 4.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) OppC_N PF12911.7 EAU86419.2 - 0.016 15.1 0.7 0.49 10.4 0.1 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF515 PF04415.12 EAU86419.2 - 0.031 12.7 0.5 0.044 12.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Syndecan PF01034.20 EAU86419.2 - 0.12 12.4 0.3 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 Syndecan domain NACHT PF05729.12 EAU86422.2 - 1.9e-07 31.2 0.0 6.6e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU86422.2 - 1.1e-05 25.9 0.1 3.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU86422.2 - 5.9e-05 23.4 0.0 0.0028 17.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAU86422.2 - 0.0054 16.0 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EAU86422.2 - 0.013 15.9 0.2 0.1 13.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAU86422.2 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU86422.2 - 0.083 12.4 0.1 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EAU86422.2 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Syntaxin_2 PF14523.6 EAU86422.2 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Syntaxin-like protein ATPase_2 PF01637.18 EAU86422.2 - 0.12 12.2 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ResIII PF04851.15 EAU86422.2 - 0.15 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GST_N_3 PF13417.6 EAU86423.1 - 6.4e-13 48.9 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU86423.1 - 1.3e-09 38.2 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU86423.1 - 0.00021 21.2 0.1 0.00064 19.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU86423.1 - 0.0021 18.2 0.0 0.0047 17.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU86423.1 - 0.0028 17.8 0.0 0.0047 17.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EAU86423.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GMC_oxred_N PF00732.19 EAU86424.1 - 7.1e-68 229.1 0.0 8.8e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU86424.1 - 4.9e-36 124.4 0.0 1.3e-35 123.1 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EAU86424.1 - 0.0016 17.7 0.1 0.0033 16.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU86424.1 - 0.0026 17.1 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EAU86424.1 - 0.0027 17.9 0.0 0.0085 16.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU86424.1 - 0.005 15.9 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAU86424.1 - 0.0098 15.0 0.0 0.03 13.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EAU86424.1 - 0.043 13.4 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAU86424.1 - 0.064 12.5 0.0 4.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NACHT PF05729.12 EAU86425.2 - 7.7e-08 32.4 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU86425.2 - 0.00013 22.4 0.3 0.0036 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EAU86425.2 - 0.0016 18.8 0.1 0.073 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAU86425.2 - 0.007 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 EAU86425.2 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAU86425.2 - 0.025 13.8 0.0 0.063 12.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF3369 PF11849.8 EAU86425.2 - 0.047 13.9 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) ATP_bind_1 PF03029.17 EAU86425.2 - 0.098 12.4 2.3 0.41 10.4 0.1 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EAU86425.2 - 0.13 12.5 0.1 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2791 PF10923.8 EAU86425.2 - 0.18 10.7 0.0 0.34 9.7 0.0 1.5 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Wbp11 PF09429.10 EAU86425.2 - 0.94 9.9 4.7 3.9 7.9 0.2 2.6 2 0 0 2 2 2 0 WW domain binding protein 11 adh_short PF00106.25 EAU86426.2 - 1e-29 103.4 0.0 1.7e-25 89.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86426.2 - 1e-18 67.8 0.0 3.9e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU86426.2 - 1.1e-08 35.2 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU86426.2 - 8.8e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAU86426.2 - 0.00087 18.8 0.1 0.011 15.2 0.1 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EAU86426.2 - 0.0044 17.1 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EAU86426.2 - 0.02 14.0 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EAU86426.2 - 0.041 14.1 0.1 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 EAU86426.2 - 0.061 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4297 PF14130.6 EAU86426.2 - 0.083 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4297) ArenaCapSnatch PF17296.2 EAU86426.2 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Arenavirus cap snatching domain NAD_binding_10 PF13460.6 EAU86426.2 - 0.17 11.7 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Pkinase PF00069.25 EAU86427.1 - 3.1e-70 236.5 0.0 4e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86427.1 - 8.7e-42 143.2 0.0 1.2e-41 142.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU86427.1 - 5.9e-07 29.1 0.0 1.4e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EAU86427.1 - 0.03 14.2 0.6 2.7 7.8 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EAU86427.1 - 0.075 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAU86427.1 - 0.08 12.6 0.1 0.51 9.9 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EAU86427.1 - 0.089 11.5 2.0 0.22 10.3 1.7 1.6 1 1 0 1 1 1 0 Fungal protein kinase Apt1 PF10351.9 EAU86427.1 - 0.76 8.6 6.6 0.9 8.3 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EAU86427.1 - 6.4 5.2 13.4 9.5 4.6 13.4 1.3 1 1 0 1 1 1 0 Macoilin family Mob1_phocein PF03637.17 EAU86429.2 - 7.2e-67 224.6 0.5 9.4e-67 224.3 0.5 1.1 1 0 0 1 1 1 1 Mob1/phocein family ORC6 PF05460.13 EAU86429.2 - 0.51 9.6 4.7 0.097 11.9 1.5 1.4 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF5427 PF10310.9 EAU86429.2 - 0.72 8.7 3.6 0.59 9.0 1.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5427) TPR_10 PF13374.6 EAU86431.1 - 1.7e-05 24.5 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU86431.1 - 8.5e-05 22.8 0.0 1.7 9.0 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU86431.1 - 8.7e-05 22.2 0.2 0.49 10.3 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU86431.1 - 0.00091 18.9 0.0 2.6 7.8 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 EAU86431.1 - 0.0012 18.9 0.0 7.1 7.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU86431.1 - 0.0047 16.9 0.2 1.3 9.4 0.0 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF4246 PF14033.6 EAU86432.1 - 7.5e-178 592.3 0.0 9.5e-178 591.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) EBV-NA3 PF05009.12 EAU86432.1 - 0.012 15.1 0.5 0.02 14.4 0.5 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) 2OG-FeII_Oxy_5 PF13759.6 EAU86432.1 - 0.052 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DNA_pol_phi PF04931.13 EAU86432.1 - 6.2 4.8 11.4 9.3 4.2 11.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_28 PF00295.17 EAU86434.2 - 2e-42 145.4 0.0 4e-42 144.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 EAU86434.2 - 0.031 14.1 4.1 0.045 13.6 0.9 2.4 1 1 1 2 2 2 0 Right handed beta helix region Pro_isomerase PF00160.21 EAU86435.1 - 7e-50 169.4 0.2 2e-49 167.9 0.1 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EAU86435.1 - 1.8e-08 34.9 0.1 0.00071 20.3 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Casein PF00363.18 EAU86435.1 - 0.17 12.2 0.3 1.3 9.5 0.1 2.2 2 0 0 2 2 2 0 Casein Cutinase PF01083.22 EAU86436.1 - 1.9e-46 158.3 0.1 2.1e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EAU86436.1 - 0.00013 21.6 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EAU86436.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Lipase PF00151.19 EAU86436.1 - 0.067 12.5 0.1 0.091 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipase F-box-like PF12937.7 EAU86437.2 - 4.6e-11 42.4 0.2 1.4e-10 40.9 0.2 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86437.2 - 4.2e-05 23.3 0.3 0.00023 21.0 0.3 2.3 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EAU86437.2 - 0.15 12.5 1.1 1.1e+02 3.4 0.1 4.5 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) NAD_binding_10 PF13460.6 EAU86439.1 - 1.9e-05 24.6 0.0 0.00054 19.9 0.0 2.6 1 1 1 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EAU86439.1 - 0.051 13.0 0.3 1.2 8.5 0.1 2.6 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NDK PF00334.19 EAU86440.1 - 1e-16 61.2 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4246 PF14033.6 EAU86441.2 - 7.9e-177 588.9 0.0 9.6e-177 588.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EAU86441.2 - 0.011 16.1 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Ank_2 PF12796.7 EAU86442.2 - 3.3e-99 325.6 29.1 4.1e-14 52.9 0.1 7.6 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU86442.2 - 9.5e-54 179.1 17.3 1.8e-07 31.6 0.0 12.2 5 2 8 13 13 13 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU86442.2 - 1.8e-48 156.9 9.5 0.0028 18.0 0.0 14.0 13 1 0 13 13 13 12 Ankyrin repeat Ank PF00023.30 EAU86442.2 - 9.1e-45 149.2 21.1 8.4e-05 22.8 0.5 13.3 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 EAU86442.2 - 7.2e-38 128.2 25.0 1.6e-05 25.1 0.1 11.0 3 3 8 11 11 11 10 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU86442.2 - 4.6e-08 33.4 0.1 1.7e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU86442.2 - 3.3e-05 23.9 0.1 7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Ribosomal_S11 PF00411.19 EAU86442.2 - 0.0023 18.3 0.5 53 4.3 0.0 5.6 5 1 1 6 6 6 0 Ribosomal protein S11 COX2-transmemb PF09125.10 EAU86442.2 - 0.029 14.2 0.2 1e+02 2.8 0.0 4.0 4 0 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane NB-ARC PF00931.22 EAU86442.2 - 0.067 12.4 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF4246 PF14033.6 EAU86443.2 - 4.2e-167 556.8 0.0 5.7e-167 556.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EAU86443.2 - 0.022 15.1 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase OAR PF03826.17 EAU86443.2 - 0.11 12.4 0.3 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 OAR domain F-box-like PF12937.7 EAU86444.2 - 3.1e-08 33.4 0.8 6.4e-08 32.4 0.8 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU86444.2 - 0.023 15.1 1.0 28 5.3 0.1 4.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Prefoldin_2 PF01920.20 EAU86444.2 - 0.078 12.9 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF5082 PF16888.5 EAU86444.2 - 0.49 10.7 0.1 0.49 10.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CDC37_N PF03234.14 EAU86445.1 - 3.6e-43 147.6 0.6 3.6e-43 147.6 0.6 2.6 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EAU86445.1 - 9.4e-37 125.5 2.2 1e-36 125.4 0.0 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EAU86445.1 - 4.3e-19 68.5 0.1 4.3e-19 68.5 0.1 3.1 2 1 0 2 2 2 1 Cdc37 C terminal domain IZUMO PF15005.6 EAU86445.1 - 0.28 11.7 2.9 0.22 12.1 0.8 1.9 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Vir_act_alpha_C PF10400.9 EAU86446.2 - 0.036 14.7 1.3 0.062 14.0 1.3 1.3 1 0 0 1 1 1 0 Virulence activator alpha C-term Cu_bind_like PF02298.17 EAU86447.1 - 0.0024 17.9 0.1 0.011 15.8 0.1 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain MSP PF01716.18 EAU86447.1 - 0.11 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide DUF883 PF05957.13 EAU86447.1 - 0.2 12.3 1.6 0.39 11.3 1.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) BBIP10 PF14777.6 EAU86448.2 - 0.16 11.5 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 F-box-like PF12937.7 EAU86449.2 - 1e-07 31.7 0.8 3.6e-07 30.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like Mob1_phocein PF03637.17 EAU86452.1 - 9e-63 211.3 0.3 1.1e-62 211.0 0.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family zf-RING_2 PF13639.6 EAU86453.1 - 0.0018 18.6 0.2 0.0039 17.5 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU86453.1 - 0.049 13.7 0.3 0.16 12.0 0.1 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 EAU86453.1 - 0.063 13.0 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EAU86453.1 - 0.2 12.0 1.8 0.66 10.3 1.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain OATP PF03137.20 EAU86453.1 - 0.25 9.6 1.2 0.37 9.0 0.0 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Mucin PF01456.17 EAU86453.1 - 1.4 8.9 25.3 4.1 7.4 3.5 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DEAD PF00270.29 EAU86454.2 - 1.9e-07 31.0 0.0 0.0011 18.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU86454.2 - 2.6e-05 24.5 0.0 0.00031 21.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3707 PF12499.8 EAU86455.2 - 0.18 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Pherophorin Syntaxin-6_N PF09177.11 EAU86456.1 - 0.0032 18.0 3.6 0.0053 17.3 3.6 1.3 1 0 0 1 1 1 1 Syntaxin 6, N-terminal WXG100 PF06013.12 EAU86456.1 - 0.12 12.6 1.0 0.3 11.3 0.2 2.1 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Exonuc_VII_L PF02601.15 EAU86456.1 - 0.69 9.4 3.9 0.88 9.1 3.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5486 PF17588.2 EAU86461.1 - 0.057 13.3 0.9 0.15 12.0 0.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5486) DUF3340 PF11818.8 EAU86461.1 - 2.5 8.3 7.3 0.52 10.5 1.3 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) SOG2 PF10428.9 EAU86461.1 - 6.1 5.9 33.6 11 5.0 33.6 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein F-box-like PF12937.7 EAU86462.1 - 5.1e-05 23.1 0.7 0.00024 20.9 0.2 2.5 3 0 0 3 3 3 1 F-box-like Peptidase_M36 PF02128.15 EAU86463.1 - 7.7e-141 469.5 8.0 9.3e-141 469.3 8.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EAU86463.1 - 7.9e-05 22.4 0.1 0.00024 20.9 0.1 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PepSY PF03413.19 EAU86463.1 - 0.014 15.9 0.1 0.041 14.5 0.1 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF1202 PF06717.11 EAU86463.1 - 0.087 12.2 1.2 0.14 11.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Methyltransf_11 PF08241.12 EAU86466.2 - 3.1e-15 56.6 0.0 5.5e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU86466.2 - 4.1e-15 55.9 0.1 5.5e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU86466.2 - 5.3e-15 55.9 0.0 1.1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU86466.2 - 4e-14 52.8 0.0 9.3e-14 51.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU86466.2 - 7.3e-13 49.1 0.0 1.3e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU86466.2 - 8.1e-07 28.7 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EAU86466.2 - 1.5e-06 27.8 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EAU86466.2 - 7.6e-06 25.5 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EAU86466.2 - 0.00027 20.6 0.0 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TPMT PF05724.11 EAU86466.2 - 0.00097 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 EAU86466.2 - 0.0036 17.0 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EAU86466.2 - 0.0066 15.8 0.0 0.0081 15.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EAU86466.2 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 EAU86466.2 - 0.054 13.3 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.6 EAU86466.2 - 0.055 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EAU86466.2 - 0.12 11.5 0.0 0.21 10.6 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.20 EAU86466.2 - 0.17 10.9 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DLH PF01738.18 EAU86468.1 - 1.7e-18 67.0 0.2 2.1e-18 66.7 0.2 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EAU86468.1 - 0.057 12.9 0.1 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family GFO_IDH_MocA PF01408.22 EAU86469.1 - 2.4e-10 41.3 0.0 4.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold MutL PF13941.6 EAU86471.1 - 0.12 11.0 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 MutL protein CshA_NR2 PF18651.1 EAU86473.1 - 0.0098 15.1 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Surface adhesin CshA non-repetitive domain 2 DLH PF01738.18 EAU86474.1 - 1.3e-20 73.9 0.1 1.7e-20 73.5 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EAU86474.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family GFO_IDH_MocA PF01408.22 EAU86475.1 - 6.5e-11 43.1 0.0 1e-10 42.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cerato-platanin PF07249.12 EAU86476.1 - 1e-11 45.0 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.12 EAU86477.1 - 8.5e-07 29.1 0.1 1.4e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Cerato-platanin CAP_N PF01213.19 EAU86477.1 - 0.28 10.6 2.7 0.34 10.4 2.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EAU86477.1 - 2 8.4 6.4 2.8 7.9 6.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DDDD PF10161.9 EAU86478.1 - 0.002 17.8 0.1 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 Putative mitochondrial precursor protein YrhC PF14143.6 EAU86478.1 - 0.097 12.8 0.4 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 YrhC-like protein GFO_IDH_MocA PF01408.22 EAU86479.1 - 9e-05 23.3 0.0 0.00086 20.1 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAU86479.1 - 0.094 12.7 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain EphA2_TM PF14575.6 EAU86480.1 - 0.012 16.5 0.0 0.031 15.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rick_17kDa_Anti PF05433.15 EAU86480.1 - 0.019 14.8 4.5 0.053 13.4 4.5 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EAU86480.1 - 0.02 14.9 2.7 0.054 13.5 2.7 1.7 1 0 0 1 1 1 0 Glycine zipper Syndecan PF01034.20 EAU86480.1 - 0.028 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain MetRS-N PF09635.10 EAU86489.2 - 0.05 14.1 0.2 0.065 13.8 0.2 1.1 1 0 0 1 1 1 0 MetRS-N binding domain Focal_AT PF03623.13 EAU86489.2 - 0.053 13.5 0.2 0.15 12.0 0.2 1.7 1 1 0 1 1 1 0 Focal adhesion targeting region TACC_C PF05010.14 EAU86495.2 - 0.00098 19.0 5.2 0.0018 18.1 5.2 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF5644 PF18712.1 EAU86495.2 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5644) HMG_box_2 PF09011.10 EAU86496.2 - 0.0041 17.7 3.7 0.0041 17.7 3.7 2.6 2 0 0 2 2 2 1 HMG-box domain Tet_JBP PF12851.7 EAU86498.2 - 1.4e-13 50.9 0.0 3.8e-13 49.5 0.0 1.6 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.7 EAU86499.1 - 2.4e-11 43.6 0.0 5.7e-09 35.8 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily CCDC-167 PF15188.6 EAU86502.1 - 0.055 13.8 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 KDZ PF18758.1 EAU86504.2 - 3e-45 154.5 0.2 8.1e-45 153.2 0.2 1.8 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU86504.2 - 1.1e-20 73.7 0.0 2.7e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Rubredoxin_2 PF18073.1 EAU86504.2 - 0.33 10.7 13.0 0.28 10.9 5.8 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain HMG_box_2 PF09011.10 EAU86505.2 - 0.0021 18.6 0.1 0.0087 16.6 0.1 2.0 1 0 0 1 1 1 1 HMG-box domain DUF4482 PF14818.6 EAU86506.1 - 0.12 13.2 0.5 0.57 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Legionella_OMP PF05150.12 EAU86509.2 - 0.08 11.9 0.1 1.8 7.4 0.1 2.2 2 0 0 2 2 2 0 Legionella pneumophila major outer membrane protein precursor Pkinase PF00069.25 EAU86510.2 - 1.1e-20 74.2 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86510.2 - 4.6e-07 29.4 0.0 3.2e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase F-box PF00646.33 EAU86510.2 - 0.01 15.7 0.3 0.035 14.0 0.3 2.0 1 0 0 1 1 1 0 F-box domain PIF1 PF05970.14 EAU86511.2 - 0.0022 17.3 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase NB-ARC PF00931.22 EAU86511.2 - 0.0036 16.5 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EAU86511.2 - 0.01 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAU86511.2 - 0.03 14.7 0.0 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain PaaX_C PF08223.11 EAU86516.2 - 0.032 14.5 0.0 0.69 10.2 0.0 2.2 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Toxin_19 PF08088.12 EAU86516.2 - 0.62 10.2 3.1 1.1 9.5 3.1 1.4 1 0 0 1 1 1 0 Conotoxin I-superfamily F-box-like PF12937.7 EAU86517.1 - 1.6e-08 34.3 0.2 4.4e-08 32.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU86518.1 - 1.5e-06 28.0 0.1 4.7e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86518.1 - 0.00029 20.6 0.1 0.00029 20.6 0.1 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EAU86518.1 - 0.33 11.4 7.8 0.51 10.8 0.1 4.4 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) CBM_1 PF00734.18 EAU86519.2 - 1.8e-07 31.0 0.3 2.8e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain PIF1 PF05970.14 EAU86521.2 - 4.6e-112 374.8 0.0 6.4e-112 374.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EAU86521.2 - 8.2e-63 212.1 0.0 1.6e-62 211.1 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAU86521.2 - 3.9e-09 36.5 0.0 6.7e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EAU86521.2 - 0.00028 20.7 0.0 0.00066 19.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EAU86521.2 - 0.0047 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 EAU86521.2 - 0.0054 14.7 0.0 0.0081 14.1 0.0 1.1 1 0 0 1 1 1 1 Helicase Terminase_GpA PF05876.12 EAU86521.2 - 0.067 11.7 0.2 0.11 11.0 0.2 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) ResIII PF04851.15 EAU86521.2 - 0.074 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAU86521.2 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 EAU86521.2 - 0.16 10.8 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Torsin PF06309.11 EAU86521.2 - 0.21 11.7 0.2 1 9.5 0.0 2.2 3 0 0 3 3 2 0 Torsin F-box-like PF12937.7 EAU86522.2 - 0.021 14.7 0.6 0.21 11.5 0.1 2.9 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 EAU86522.2 - 0.025 14.4 0.1 0.025 14.4 0.1 2.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 EAU86523.2 - 5.4e-05 23.0 0.3 0.00012 21.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like Ribosomal_S13_N PF08069.12 EAU86525.2 - 0.009 16.0 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Rab5ip PF07019.12 EAU86525.2 - 0.012 16.2 0.4 0.62 10.7 0.0 2.1 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) PX PF00787.24 EAU86527.1 - 3.8e-14 52.6 0.0 8.9e-14 51.4 0.0 1.5 2 0 0 2 2 2 1 PX domain F-box PF00646.33 EAU86530.2 - 0.25 11.3 0.0 0.25 11.3 0.0 3.0 3 0 0 3 3 3 0 F-box domain Hva1_TUDOR PF11160.8 EAU86531.1 - 2.1e-19 69.5 0.1 2.3e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain CBM_1 PF00734.18 EAU86532.2 - 8.5e-11 41.6 1.7 8.5e-11 41.6 1.7 4.6 5 0 0 5 5 5 1 Fungal cellulose binding domain F-box-like PF12937.7 EAU86533.2 - 1.4e-07 31.3 5.8 0.0001 22.2 0.4 3.5 4 0 0 4 4 4 2 F-box-like F-box PF00646.33 EAU86533.2 - 0.0028 17.5 0.6 0.029 14.2 0.6 2.8 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 EAU86533.2 - 0.12 12.2 1.5 7 6.5 0.1 3.9 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.7 EAU86538.2 - 7.7e-08 32.1 0.0 2.5e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU86539.2 - 5.3e-07 29.4 2.3 1.9e-06 27.7 0.0 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EAU86539.2 - 0.0085 15.9 0.2 0.039 13.8 0.2 2.2 1 1 0 1 1 1 1 F-box domain CBM_1 PF00734.18 EAU86540.2 - 7.4e-07 29.0 0.3 7.4e-07 29.0 0.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Mpv17_PMP22 PF04117.12 EAU86541.1 - 1.2e-20 73.5 0.2 2.4e-20 72.5 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1129 PF06570.11 EAU86541.1 - 0.1 12.0 0.1 0.35 10.3 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) AhpC-TSA PF00578.21 EAU86548.1 - 8e-27 93.6 0.0 1e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAU86548.1 - 2e-19 69.7 0.0 2.8e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin HMG14_17 PF01101.18 EAU86548.1 - 1.9e-07 31.9 15.0 4.9e-07 30.6 15.0 1.7 1 0 0 1 1 1 1 HMG14 and HMG17 AhpC-TSA_2 PF13911.6 EAU86548.1 - 0.08 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme LRR_6 PF13516.6 EAU86549.2 - 3.3e-09 36.1 26.9 0.084 13.0 0.9 8.3 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 EAU86549.2 - 4.5e-05 23.7 18.8 0.25 11.8 0.3 5.6 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) GAT PF03127.14 EAU86549.2 - 0.018 15.4 0.1 0.047 14.0 0.1 1.7 1 0 0 1 1 1 0 GAT domain LRR_1 PF00560.33 EAU86549.2 - 0.29 11.8 14.1 46 5.1 0.1 6.8 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 EAU86549.2 - 0.45 10.3 23.2 14 5.5 3.3 6.2 5 2 0 5 5 5 0 Leucine rich repeat GST_N_3 PF13417.6 EAU86550.2 - 2.1e-06 28.1 0.0 4.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU86550.2 - 3.4e-05 24.1 0.1 5.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU86550.2 - 4e-05 23.5 1.2 7.3e-05 22.7 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU86550.2 - 0.0031 17.7 0.0 0.0073 16.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU86550.2 - 0.0074 16.5 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TAL_FSA PF00923.19 EAU86551.1 - 9.5e-94 313.9 0.0 1.1e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Solute_trans_a PF03619.16 EAU86552.2 - 3.3e-95 318.6 11.9 3.9e-95 318.4 11.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Redoxin PF08534.10 EAU86553.2 - 3.7e-37 127.3 0.0 4.2e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EAU86553.2 - 1.8e-12 47.3 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ribosomal_L7Ae PF01248.26 EAU86554.2 - 3.9e-22 77.8 1.1 6.4e-22 77.1 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pkinase PF00069.25 EAU86555.1 - 1.8e-11 44.0 0.0 2.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86555.1 - 2.7e-05 23.6 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU86555.1 - 9.1e-05 21.4 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase GRIP PF01465.20 EAU86555.1 - 0.03 14.2 0.2 0.3 11.0 0.2 2.3 1 1 0 1 1 1 0 GRIP domain PreAtp-grasp PF18604.1 EAU86555.1 - 0.087 12.5 0.2 13 5.4 0.0 2.3 2 0 0 2 2 2 0 Pre ATP-grasp domain Pex19 PF04614.12 EAU86564.1 - 6.4e-64 216.1 0.5 6.4e-64 216.1 0.5 1.5 2 0 0 2 2 2 1 Pex19 protein family Ribosomal_60s PF00428.19 EAU86564.1 - 4 8.1 10.0 11 6.7 1.4 3.7 2 1 2 4 4 4 0 60s Acidic ribosomal protein AA_permease PF00324.21 EAU86568.1 - 4.2e-139 464.2 31.7 4.9e-139 464.0 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAU86568.1 - 6.8e-36 124.0 36.0 8.8e-36 123.6 36.0 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0767 PF15990.5 EAU86568.1 - 0.19 11.9 0.1 4.1 7.6 0.0 2.6 2 0 0 2 2 2 0 UPF0767 family T_cell_tran_alt PF15128.6 EAU86568.1 - 1.5 8.6 5.4 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3413 PF11893.8 EAU86569.2 - 0.076 12.2 5.1 0.088 12.0 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) Asp PF00026.23 EAU86572.1 - 2.9e-06 27.0 0.0 6.7e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease PIF1 PF05970.14 EAU86573.2 - 0.00037 19.8 0.0 0.0026 17.0 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_33 PF13671.6 EAU86573.2 - 0.038 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAU86573.2 - 0.06 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAU86573.2 - 0.3 10.8 1.1 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase FCP1_C PF09309.10 EAU86576.2 - 0.14 12.0 4.3 0.31 10.9 1.4 2.2 2 0 0 2 2 2 0 FCP1, C-terminal Allexi_40kDa PF05549.11 EAU86579.1 - 0.041 13.4 2.4 0.051 13.1 2.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1635 PF07795.11 EAU86579.1 - 0.046 13.6 7.3 0.031 14.1 5.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) Asp PF00026.23 EAU86582.2 - 5.1e-07 29.4 2.0 2.3e-05 24.0 2.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU86582.2 - 0.042 14.1 0.2 1.1 9.4 0.0 2.4 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Peptidase_M14 PF00246.24 EAU86583.2 - 1e-59 202.8 0.0 1.4e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase FAD_binding_4 PF01565.23 EAU86584.1 - 3.3e-18 65.8 1.1 5e-18 65.2 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Acetyltransf_2 PF00797.17 EAU86585.1 - 4.4e-27 95.4 0.0 2.4e-26 93.0 0.0 2.0 1 1 0 1 1 1 1 N-acetyltransferase DPPIV_rep PF18811.1 EAU86585.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.0 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region p450 PF00067.22 EAU86586.2 - 1.7e-66 224.9 0.1 3e-66 224.0 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EAU86587.2 - 1.8e-42 145.6 41.1 1.8e-42 145.6 41.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EAU86587.2 - 1.7e-05 24.3 5.7 1.7e-05 24.3 5.7 2.9 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB FolB PF02152.18 EAU86588.2 - 1.8e-28 99.3 0.0 3.9e-16 59.6 0.0 2.5 2 1 0 2 2 2 2 Dihydroneopterin aldolase ATG13 PF10033.9 EAU86589.2 - 3.1e-38 131.8 0.0 4.3e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF3915 PF13054.6 EAU86589.2 - 5.2 7.1 5.2 11 6.0 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Chorion_3 PF05387.11 EAU86594.1 - 3.2 7.3 6.4 3 7.4 6.4 1.0 1 0 0 1 1 1 0 Chorion family 3 Peptidase_S8 PF00082.22 EAU86596.2 - 9.1e-21 74.4 13.4 8.4e-20 71.2 13.4 2.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAU86596.2 - 8.1e-06 26.4 0.0 3.9e-05 24.2 0.0 2.0 1 1 1 2 2 2 1 Peptidase inhibitor I9 FAM176 PF14851.6 EAU86599.1 - 0.56 9.9 1.4 1.5 8.5 0.1 2.0 2 0 0 2 2 2 0 FAM176 family Sugar_tr PF00083.24 EAU86601.1 - 1e-106 357.5 14.1 1.3e-106 357.2 14.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU86601.1 - 8.3e-20 71.0 29.4 3.4e-15 55.8 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EAU86601.1 - 1.4e-06 27.1 12.0 1e-05 24.3 0.3 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EAU86601.1 - 0.00078 18.0 0.8 0.00078 18.0 0.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 EAU86601.1 - 0.2 12.2 3.2 1.2 9.7 2.2 2.6 1 1 1 2 2 2 0 Phage holin family 2 CENP-B_dimeris PF09026.10 EAU86602.2 - 0.15 12.5 9.5 0.26 11.7 9.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EAU86602.2 - 0.22 11.6 0.9 0.35 10.9 0.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EAU86602.2 - 1.3 8.3 8.5 1.8 7.8 8.5 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EAU86602.2 - 1.7 6.8 3.2 2.4 6.3 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RNase_P_p30 PF01876.16 EAU86606.2 - 1.1e-37 129.6 0.0 1.4e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Acetyltransf_2 PF00797.17 EAU86607.2 - 1.2e-26 93.9 0.0 5.7e-24 85.2 0.0 2.5 2 1 0 2 2 2 2 N-acetyltransferase zf-CCCH PF00642.24 EAU86608.1 - 0.011 15.6 0.7 0.019 14.9 0.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EAU86608.1 - 0.13 12.1 0.9 0.21 11.4 0.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger THEG4 PF15834.5 EAU86609.1 - 0.015 15.4 0.5 0.025 14.6 0.5 1.4 1 0 0 1 1 1 0 Testis highly expressed protein 4 DBR1 PF05011.13 EAU86610.2 - 5.9e-40 136.9 0.0 7.9e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain zf-MYND PF01753.18 EAU86612.2 - 2.5e-10 40.3 5.5 5.5e-10 39.2 5.5 1.6 1 0 0 1 1 1 1 MYND finger tRNA_NucTran2_2 PF13735.6 EAU86612.2 - 0.018 15.1 0.2 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative F-box-like PF12937.7 EAU86613.2 - 4e-07 29.8 0.0 1.4e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like HTH_31 PF13560.6 EAU86618.1 - 8e-09 35.7 0.0 9e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EAU86618.1 - 1.2e-08 34.9 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EAU86618.1 - 0.00043 20.3 0.0 0.00047 20.1 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.6 EAU86618.1 - 0.001 19.4 0.0 0.0013 19.1 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain bVLRF1 PF18826.1 EAU86618.1 - 0.089 12.7 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor Ribosomal_S11 PF00411.19 EAU86619.1 - 8.7e-47 158.1 1.9 1.1e-46 157.7 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EAU86619.1 - 0.086 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Acyltransferase PF01553.21 EAU86620.2 - 2.6e-15 56.2 0.0 3.7e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-C3HC4_3 PF13920.6 EAU86621.2 - 1.4e-07 31.3 4.7 2.3e-07 30.5 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU86621.2 - 1.9e-07 31.0 5.1 3.1e-07 30.3 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU86621.2 - 2e-07 30.9 3.5 1e-06 28.6 3.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EAU86621.2 - 7.6e-07 28.9 5.6 1.5e-06 28.0 5.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAU86621.2 - 9e-07 29.1 7.8 1.5e-06 28.4 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAU86621.2 - 5.2e-05 23.0 7.4 8.8e-05 22.3 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU86621.2 - 0.00023 20.9 8.3 0.0004 20.2 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RasGAP_C PF03836.15 EAU86621.2 - 0.02 15.1 0.0 0.16 12.1 0.0 2.7 1 0 0 1 1 1 0 RasGAP C-terminus zf-RING_4 PF14570.6 EAU86621.2 - 0.071 12.9 7.1 0.11 12.3 7.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EAU86621.2 - 0.12 12.6 8.0 0.29 11.3 8.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EAU86621.2 - 0.14 11.9 3.6 0.28 10.9 3.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 EAU86621.2 - 0.23 11.4 1.1 0.43 10.5 1.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EAU86621.2 - 0.75 10.0 4.2 4.5 7.5 4.4 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 CorA PF01544.18 EAU86621.2 - 1.2 8.4 3.3 2.3 7.5 3.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein zf-rbx1 PF12678.7 EAU86621.2 - 3.9 7.8 5.9 8.8 6.7 5.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Synaptobrevin PF00957.21 EAU86622.2 - 1.5e-28 98.4 0.2 2.1e-28 97.9 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAU86622.2 - 5.6e-23 80.8 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec61_beta PF03911.16 EAU86624.1 - 2.1e-17 62.8 0.4 2.7e-17 62.5 0.4 1.2 1 0 0 1 1 1 1 Sec61beta family Pkinase PF00069.25 EAU86626.1 - 0.00026 20.5 0.0 0.00054 19.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86626.1 - 0.0019 17.6 0.0 0.0042 16.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU86626.1 - 0.0037 16.1 0.1 0.0099 14.7 0.0 1.5 1 1 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 EAU86626.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Wza_C PF18412.1 EAU86626.1 - 0.058 13.1 0.1 0.058 13.1 0.1 1.8 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain SET PF00856.28 EAU86628.2 - 1.2e-15 58.3 0.3 6.7e-13 49.4 0.3 2.4 1 1 0 1 1 1 1 SET domain DUF4834 PF16118.5 EAU86628.2 - 7.3 7.6 8.1 52 4.9 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) TIM PF00121.18 EAU86629.1 - 2.9e-91 305.2 0.0 3.3e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Glyco_hydro_15 PF00723.21 EAU86629.1 - 0.078 11.7 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Beach PF02138.18 EAU86631.2 - 2.3e-109 365.0 0.0 5.1e-109 363.9 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 EAU86631.2 - 8.1e-09 35.8 0.0 2.9e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 EAU86631.2 - 1.7e-07 31.3 0.0 3.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 EAU86631.2 - 9.3e-05 21.8 0.5 0.00063 19.1 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) MMS19_N PF14500.6 EAU86631.2 - 0.08 12.5 1.7 0.29 10.7 0.1 2.6 2 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II WD40 PF00400.32 EAU86631.2 - 0.14 13.1 0.9 1.7 9.7 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Mito_carr PF00153.27 EAU86632.2 - 5.8e-47 157.6 0.3 8.9e-17 60.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EthD PF07110.11 EAU86633.1 - 0.017 16.3 0.3 0.088 14.0 0.1 2.2 2 1 0 2 2 2 0 EthD domain F-box-like PF12937.7 EAU86634.1 - 1.7e-10 40.6 0.0 4.8e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86634.1 - 7.8e-05 22.4 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EAU86634.1 - 0.0024 17.7 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box Methyltransf_11 PF08241.12 EAU86635.2 - 4.7e-07 30.4 0.0 9.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU86635.2 - 2e-05 25.2 0.0 0.00012 22.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU86635.2 - 0.036 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EAU86635.2 - 0.044 14.5 0.0 0.084 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 EAU86638.1 - 4.1e-09 36.2 1.3 6.8e-09 35.5 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU86638.1 - 0.0021 17.9 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain Pkinase_fungal PF17667.1 EAU86639.1 - 1.2e-18 67.1 0.0 1.7e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU86639.1 - 0.0095 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU86640.2 - 5.6e-37 127.5 0.0 4.5e-29 101.5 0.3 2.2 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EAU86640.2 - 0.089 12.7 0.3 0.34 10.8 0.3 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Abhydrolase_9_N PF15420.6 EAU86642.2 - 0.069 13.1 2.6 0.059 13.4 1.1 1.6 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus G6B PF15096.6 EAU86642.2 - 0.09 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 G6B family PgaD PF13994.6 EAU86642.2 - 0.13 12.3 1.2 7.6 6.6 0.0 2.8 2 1 0 2 2 2 0 PgaD-like protein DUF872 PF05915.12 EAU86642.2 - 1.5 9.0 4.3 1.1 9.5 1.9 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Pil1 PF13805.6 EAU86643.2 - 2.6e-20 73.0 0.0 4e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 SAUGI PF06106.11 EAU86647.1 - 0.082 13.4 0.2 0.97 10.0 0.0 2.2 2 0 0 2 2 2 0 S. aureus uracil DNA glycosylase inhibitor Pox_G5 PF04599.12 EAU86647.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein F-box-like PF12937.7 EAU86648.1 - 2.8e-06 27.1 0.1 8e-06 25.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU86648.1 - 0.0002 21.1 0.1 0.00074 19.3 0.1 1.9 1 0 0 1 1 1 1 F-box domain DUF3666 PF12408.8 EAU86648.1 - 0.52 9.6 2.7 4.5 6.6 0.0 3.3 4 0 0 4 4 4 0 Ribose-5-phosphate isomerase SAUGI PF06106.11 EAU86649.1 - 0.0011 19.5 0.0 0.08 13.5 0.0 2.5 3 0 0 3 3 3 1 S. aureus uracil DNA glycosylase inhibitor F-box-like PF12937.7 EAU86649.1 - 0.004 17.0 0.9 0.014 15.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like CENP-B_dimeris PF09026.10 EAU86649.1 - 0.012 16.0 9.3 0.022 15.1 9.3 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain F-box PF00646.33 EAU86649.1 - 0.11 12.4 2.1 0.43 10.5 0.1 2.7 2 0 0 2 2 2 0 F-box domain RXT2_N PF08595.11 EAU86649.1 - 0.15 12.1 0.4 0.25 11.4 0.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 EAU86649.1 - 0.7 9.7 3.7 1.1 9.1 3.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 EAU86649.1 - 1.2 7.1 9.7 2 6.5 9.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EAU86649.1 - 9.3 5.6 6.6 13 5.1 6.6 1.1 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 EAU86651.2 - 1.2e-38 133.0 0.0 7.6e-38 130.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86651.2 - 3.9e-15 55.9 0.0 7.8e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAU86651.2 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU86651.2 - 0.028 14.3 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU86651.2 - 0.13 11.6 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pyr_redox_2 PF07992.14 EAU86652.1 - 3.1e-67 226.9 5.4 4.4e-67 226.4 5.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAU86652.1 - 3.5e-40 136.7 0.4 9.8e-40 135.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EAU86652.1 - 1.4e-20 73.6 8.5 1.4e-18 67.2 1.5 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAU86652.1 - 2.8e-12 46.5 4.3 7.5e-11 41.7 0.6 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EAU86652.1 - 8.6e-12 45.1 0.2 8.6e-12 45.1 0.2 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAU86652.1 - 5.4e-09 35.7 3.1 2.5e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU86652.1 - 1.8e-07 30.6 2.8 1.8e-07 30.6 2.8 2.6 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EAU86652.1 - 2.9e-07 30.6 7.6 0.00036 20.7 0.7 3.1 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EAU86652.1 - 1.6e-06 27.6 5.2 0.0091 15.3 0.7 3.2 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EAU86652.1 - 3.3e-06 26.5 0.5 0.089 11.9 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EAU86652.1 - 1.6e-05 23.8 14.8 0.00031 19.5 1.7 3.9 4 0 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 EAU86652.1 - 5.7e-05 22.5 11.0 0.009 15.3 0.8 3.9 3 1 1 4 4 4 1 FAD binding domain Thi4 PF01946.17 EAU86652.1 - 0.00017 20.9 4.4 0.001 18.3 0.2 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EAU86652.1 - 0.00051 19.7 16.4 0.11 12.0 0.3 3.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase THF_DHG_CYH_C PF02882.19 EAU86652.1 - 0.014 14.7 0.4 0.25 10.7 0.1 3.0 4 0 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 EAU86652.1 - 1.3 9.4 4.2 9.2 6.8 1.7 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EAU86652.1 - 7.5 5.5 9.5 1.4 7.9 1.1 3.2 3 1 0 3 3 3 0 Lycopene cyclase protein TMEM37 PF15108.6 EAU86654.1 - 0.057 13.3 2.3 0.058 13.3 0.6 1.7 1 1 1 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF3169 PF11368.8 EAU86654.1 - 0.2 11.1 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Pectate_lyase_3 PF12708.7 EAU86655.2 - 1.9e-96 322.1 2.7 4.4e-82 275.1 0.4 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EAU86655.2 - 6e-07 29.1 0.1 0.051 13.3 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase adh_short PF00106.25 EAU86656.2 - 1.2e-32 112.9 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86656.2 - 6.2e-25 88.1 0.0 8.5e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.19 EAU86657.2 - 3.1e-19 69.5 0.1 1.2e-18 67.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EAU86657.2 - 0.0013 19.0 0.1 0.0026 18.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAU86657.2 - 0.031 14.3 0.1 0.066 13.2 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAU86657.2 - 0.059 12.6 0.1 0.29 10.3 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase LPG_synthase_TM PF03706.13 EAU86658.2 - 0.002 17.7 1.1 0.024 14.2 0.1 2.0 2 0 0 2 2 2 2 Lysylphosphatidylglycerol synthase TM region HemY_N PF07219.13 EAU86658.2 - 0.04 14.1 0.8 2.2 8.5 0.1 2.7 2 1 1 3 3 3 0 HemY protein N-terminus PHO4 PF01384.20 EAU86659.2 - 2.1e-108 362.4 17.8 2.5e-108 362.1 17.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF3185 PF11381.8 EAU86659.2 - 0.071 13.1 0.1 0.071 13.1 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3185) DUF1673 PF07895.11 EAU86659.2 - 0.11 12.2 1.9 0.32 10.7 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF4010 PF13194.6 EAU86660.2 - 0.02 14.5 0.7 0.02 14.5 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Neurensin PF14927.6 EAU86660.2 - 0.084 12.6 3.5 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Neurensin DUF2613 PF11021.8 EAU86660.2 - 0.15 12.2 0.2 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) SUR7 PF06687.12 EAU86660.2 - 0.51 9.9 5.6 0.43 10.2 1.6 2.0 2 0 0 2 2 2 0 SUR7/PalI family adh_short PF00106.25 EAU86661.2 - 1.4e-29 103.0 0.0 6.9e-29 100.7 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU86661.2 - 8.3e-19 68.1 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU86661.2 - 0.0021 18.0 0.0 0.0029 17.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU86661.2 - 0.084 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hemerythrin PF01814.23 EAU86662.1 - 1.6e-09 38.5 0.8 2.3e-09 38.0 0.8 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4890 PF16231.5 EAU86662.1 - 0.014 15.9 0.5 0.027 15.0 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) FANCI_HD2 PF14680.6 EAU86662.1 - 0.04 13.2 1.2 0.059 12.6 1.2 1.2 1 0 0 1 1 1 0 FANCI helical domain 2 DUF4214 PF13946.6 EAU86662.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Hemerythrin PF01814.23 EAU86663.1 - 6.2e-10 39.8 1.2 1.7e-09 38.4 1.7 1.4 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF4207 PF13904.6 EAU86664.1 - 0.14 11.9 0.5 0.26 10.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) F-box-like PF12937.7 EAU86666.2 - 4.3e-05 23.3 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like V-SNARE_C PF12352.8 EAU86666.2 - 0.033 14.5 1.0 0.92 9.8 0.4 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Peptidase_U4 PF03419.13 EAU86670.2 - 0.096 12.0 5.8 0.13 11.6 5.8 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA FHA PF00498.26 EAU86673.2 - 1.9e-14 53.8 0.0 3.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EAU86673.2 - 6.5e-11 41.8 8.7 1.1e-10 41.1 8.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EAU86673.2 - 2e-07 31.2 14.6 2.9e-07 30.7 14.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EAU86673.2 - 0.0012 18.8 12.8 0.0019 18.1 12.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAU86673.2 - 0.0012 18.8 3.9 0.0019 18.2 3.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EAU86673.2 - 0.0024 17.7 15.4 0.0038 17.0 15.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU86673.2 - 0.0034 17.2 15.0 0.0053 16.6 15.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU86673.2 - 0.0096 16.2 9.4 0.017 15.4 9.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain SOG2 PF10428.9 EAU86673.2 - 1.1 8.3 3.9 1.5 7.9 3.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_UBOX PF13445.6 EAU86673.2 - 1.8 8.6 15.5 3.3 7.8 15.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EAU86673.2 - 2.2 8.0 7.6 3.9 7.2 7.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EAU86673.2 - 6.5 6.7 8.7 11 6.0 8.7 1.3 1 0 0 1 1 1 0 PHD-finger ABC_membrane PF00664.23 EAU86674.2 - 2.9e-61 207.5 34.4 4.2e-34 118.4 15.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAU86674.2 - 4.5e-54 182.7 0.1 2.5e-28 99.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAU86674.2 - 3.4e-08 33.2 5.9 0.01 15.3 0.1 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EAU86674.2 - 1e-07 32.0 0.9 0.0047 17.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EAU86674.2 - 9e-06 25.3 0.1 0.078 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EAU86674.2 - 9.7e-06 25.6 0.3 0.18 11.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EAU86674.2 - 9.7e-05 22.5 4.2 0.021 14.9 0.0 2.9 3 0 0 3 3 2 2 Dynamin family AAA_16 PF13191.6 EAU86674.2 - 0.00022 21.7 1.7 0.3 11.4 0.2 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 EAU86674.2 - 0.00022 21.8 2.0 0.47 10.9 0.0 3.2 2 1 1 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EAU86674.2 - 0.00023 21.1 0.3 0.37 10.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EAU86674.2 - 0.00064 20.0 0.9 0.092 13.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAU86674.2 - 0.00079 18.8 0.5 0.61 9.3 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.22 EAU86674.2 - 0.0048 16.1 0.2 3.5 6.7 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Roc PF08477.13 EAU86674.2 - 0.0057 16.9 0.2 4 7.7 0.1 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EAU86674.2 - 0.0068 15.8 2.1 2.2 7.6 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family DUF87 PF01935.17 EAU86674.2 - 0.013 15.6 1.8 0.67 10.0 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_pol_Rpc4 PF05132.14 EAU86674.2 - 0.021 15.2 0.3 0.021 15.2 0.3 2.8 3 0 0 3 3 3 0 RNA polymerase III RPC4 MeaB PF03308.16 EAU86674.2 - 0.028 13.4 1.3 1.8 7.5 0.2 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EAU86674.2 - 0.038 13.7 3.9 3.3 7.4 0.2 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAU86674.2 - 0.042 13.0 0.8 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 EAU86674.2 - 0.082 13.1 0.7 16 5.8 0.1 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 EAU86674.2 - 0.11 12.1 2.0 3.4 7.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EAU86674.2 - 0.15 12.0 1.5 16 5.4 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EAU86674.2 - 0.16 11.5 0.1 21 4.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EAU86674.2 - 0.18 10.6 5.2 2.9 6.7 0.0 2.7 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 EAU86674.2 - 0.19 11.5 0.6 75 3.0 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein CDC45 PF02724.14 EAU86674.2 - 0.34 9.1 4.2 0.87 7.8 4.2 1.6 1 0 0 1 1 1 0 CDC45-like protein NTPase_1 PF03266.15 EAU86674.2 - 0.55 10.1 4.2 18 5.2 0.7 3.2 3 1 0 3 3 3 0 NTPase AAA_15 PF13175.6 EAU86674.2 - 0.77 9.4 5.0 9 5.9 0.1 3.0 2 1 1 3 3 3 0 AAA ATPase domain DUF1281_C PF18406.1 EAU86675.2 - 0.11 12.2 0.0 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Ferredoxin-like domain in Api92-like protein DASH_Ask1 PF08655.10 EAU86675.2 - 0.25 11.3 0.3 2 8.4 0.5 2.5 2 1 1 3 3 3 0 DASH complex subunit Ask1 Fungal_trans PF04082.18 EAU86676.2 - 4.7e-24 84.8 0.0 8.3e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU86676.2 - 4.9e-10 39.4 10.8 1.1e-09 38.3 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 EAU86678.2 - 8.6e-29 100.9 0.0 4.2e-15 56.0 0.4 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EAU86678.2 - 0.0022 18.6 0.4 1 10.0 0.5 3.2 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 EAU86678.2 - 0.0029 17.8 3.2 0.7 10.1 1.8 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Inhibitor_I66 PF16850.5 EAU86679.2 - 2.4e-11 43.7 0.0 3.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I66 POR_N PF01855.19 EAU86679.2 - 0.19 11.4 0.6 0.24 11.1 0.6 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PhoLip_ATPase_C PF16212.5 EAU86680.1 - 9.8e-76 254.8 30.0 9.8e-76 254.8 30.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAU86680.1 - 2.7e-23 81.4 0.3 9.2e-23 79.7 0.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EAU86680.1 - 1.2e-12 47.7 0.0 2.7e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAU86680.1 - 1.8e-12 48.0 0.1 9.7e-07 29.3 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAU86680.1 - 0.00021 20.9 0.0 0.00021 20.9 0.0 3.4 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EAU86680.1 - 0.0042 16.8 0.1 0.05 13.3 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_trans_2_3 PF13632.6 EAU86690.2 - 6.2e-56 189.4 0.2 6.2e-56 189.4 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAU86690.2 - 0.00031 20.7 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EAU86690.2 - 0.0013 18.6 0.0 0.0078 16.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAU86690.2 - 0.063 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 EAU86691.2 - 2.2e-21 76.1 0.1 4.8e-21 75.0 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 vATP-synt_E PF01991.18 EAU86692.1 - 5.9e-56 189.0 12.3 6.8e-56 188.8 12.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Terminase_2 PF03592.16 EAU86692.1 - 0.085 13.3 6.6 0.31 11.5 0.0 2.5 2 1 0 2 2 2 0 Terminase small subunit DUF883 PF05957.13 EAU86692.1 - 5.3 7.7 11.8 0.92 10.2 5.4 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.9 EAU86692.1 - 6.9 5.7 10.2 9.2 5.2 10.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2_4 PF13894.6 EAU86693.2 - 5.4e-13 48.6 9.7 0.018 15.8 0.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU86693.2 - 1.3e-12 47.4 11.8 0.011 16.1 0.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.7 EAU86693.2 - 5.8e-12 45.6 3.1 0.18 12.3 0.0 4.5 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EAU86693.2 - 1.7e-07 31.0 3.8 0.17 12.0 0.0 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger ADK_lid PF05191.14 EAU86693.2 - 0.00013 21.8 0.2 6.5 6.8 0.0 4.0 3 1 0 3 3 3 1 Adenylate kinase, active site lid zf-C2H2_2 PF12756.7 EAU86693.2 - 0.0003 21.1 2.8 9.1 6.7 0.0 4.1 2 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) RNA_POL_M_15KD PF02150.16 EAU86693.2 - 0.0026 17.6 3.6 17 5.4 0.0 4.2 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit HNH_5 PF14279.6 EAU86693.2 - 0.0039 17.0 2.9 14 5.6 0.0 4.0 3 1 1 4 4 4 0 HNH endonuclease zf-C2H2_jaz PF12171.8 EAU86693.2 - 0.015 15.5 0.3 38 4.7 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Fer4_21 PF14697.6 EAU86693.2 - 0.022 14.9 3.4 9.1 6.5 0.3 3.9 4 0 0 4 4 4 0 4Fe-4S dicluster domain Rpr2 PF04032.16 EAU86693.2 - 0.034 14.4 5.7 3.3 8.0 0.4 3.7 2 1 2 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 EAU86693.2 - 0.046 13.7 12.4 3.2 7.7 0.1 4.3 4 0 0 4 4 4 0 Nudix N-terminal zinc_ribbon_4 PF13717.6 EAU86693.2 - 0.38 10.7 7.4 6.8 6.7 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Zf_RING PF16744.5 EAU86693.2 - 2.3 8.4 8.0 64 3.8 1.3 3.9 3 1 1 4 4 4 0 KIAA1045 RING finger Trm112p PF03966.16 EAU86693.2 - 5.1 7.8 7.6 67 4.2 0.0 4.0 3 2 0 3 3 3 0 Trm112p-like protein GMC_oxred_N PF00732.19 EAU86694.2 - 3.6e-67 226.8 0.0 4.5e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU86694.2 - 9.1e-32 110.6 0.0 1.6e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU86694.2 - 3.7e-05 23.9 0.0 0.00015 21.9 0.0 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU86694.2 - 0.00011 21.5 0.0 0.0069 15.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU86694.2 - 0.00027 20.1 0.1 0.02 14.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EAU86694.2 - 0.00038 19.6 0.0 0.00069 18.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EAU86694.2 - 0.0018 18.0 0.8 0.017 14.7 0.8 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EAU86694.2 - 0.0059 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.14 EAU86694.2 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 EAU86694.2 - 0.019 14.2 0.0 0.045 13.0 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EAU86694.2 - 0.095 13.3 0.1 7.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU86694.2 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EAU86695.2 - 1.2e-55 188.8 0.0 1.6e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU86695.2 - 2.8e-10 40.6 0.3 1.3e-08 35.3 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU86695.2 - 0.0056 16.0 0.1 1.9 7.6 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU86695.2 - 0.0058 16.2 0.4 0.094 12.3 0.0 2.6 1 1 2 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EAU86695.2 - 0.018 15.5 0.1 0.27 11.7 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EAU86695.2 - 0.057 13.4 1.0 12 5.9 0.0 3.1 2 1 0 2 2 2 0 FAD-NAD(P)-binding ICMT PF04140.14 EAU86696.2 - 1.3e-16 60.8 1.2 2.4e-16 59.9 0.1 2.0 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAU86696.2 - 4e-11 43.2 0.7 9e-11 42.1 0.5 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EAU86696.2 - 3.1e-06 26.2 0.1 4.6e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family RBP_receptor PF14752.6 EAU86696.2 - 0.028 13.0 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor DUF1295 PF06966.12 EAU86696.2 - 0.07 12.6 2.0 0.062 12.8 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Lipase_GDSL PF00657.22 EAU86697.1 - 2.1e-11 44.2 0.0 3.4e-11 43.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EAU86697.1 - 4.6e-05 23.9 1.4 0.0006 20.3 1.4 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SNARE PF05739.19 EAU86698.2 - 1.7e-12 47.2 0.5 2.1e-12 46.9 0.5 1.1 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 EAU86698.2 - 0.083 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Synaptobrevin RskA PF10099.9 EAU86698.2 - 0.13 12.6 0.0 0.15 12.4 0.0 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA ETRAMP PF09716.10 EAU86698.2 - 0.16 12.1 0.2 0.23 11.5 0.2 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Gram_pos_anchor PF00746.21 EAU86699.1 - 0.057 13.4 0.6 0.057 13.4 0.6 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif LnmK_N_HDF PF18238.1 EAU86699.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain ThiF PF00899.21 EAU86701.1 - 3.5e-70 236.1 0.0 5.1e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EAU86701.1 - 4.8e-15 56.2 0.1 4.2e-10 40.0 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 EAU86701.1 - 2.2e-05 25.0 0.0 5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 EAU86701.1 - 0.00011 22.5 0.0 0.00029 21.2 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EAU86701.1 - 0.088 13.1 0.1 0.89 9.8 0.1 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_71 PF03659.14 EAU86702.2 - 2.4e-107 359.0 0.0 2.9e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Rad17 PF03215.15 EAU86703.2 - 3.2e-25 89.1 0.0 5.6e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EAU86703.2 - 7.4e-05 23.2 0.0 0.00019 21.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAU86703.2 - 0.00074 19.8 0.1 0.0026 18.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU86703.2 - 0.0014 19.1 0.0 0.0042 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_6 PF12774.7 EAU86703.2 - 0.0028 16.7 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 EAU86703.2 - 0.0031 18.0 0.0 0.0067 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EAU86703.2 - 0.0035 17.7 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 EAU86703.2 - 0.0097 15.6 0.9 0.015 15.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EAU86703.2 - 0.025 14.3 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 EAU86703.2 - 0.03 14.8 0.0 0.093 13.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 EAU86703.2 - 0.045 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU86703.2 - 0.052 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EAU86703.2 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EAU86703.2 - 0.073 12.8 0.0 0.88 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SsgA PF04686.12 EAU86703.2 - 0.099 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA TsaE PF02367.17 EAU86703.2 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 3-HAO PF06052.12 EAU86705.2 - 2.9e-56 189.3 0.1 8.4e-36 122.9 0.1 2.0 1 1 1 2 2 2 2 3-hydroxyanthranilic acid dioxygenase FAD_binding_3 PF01494.19 EAU86707.2 - 2e-12 47.0 0.1 4.2e-06 26.2 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EAU86707.2 - 2.2e-09 37.0 0.7 9.6e-05 21.7 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU86707.2 - 2.2e-08 34.1 0.3 6.9e-05 22.6 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU86707.2 - 4.1e-08 33.3 0.9 2.8e-07 30.7 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU86707.2 - 4.5e-07 29.3 0.3 7.9e-07 28.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EAU86707.2 - 4.1e-06 26.3 0.6 0.021 14.1 0.3 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EAU86707.2 - 1.6e-05 25.3 0.2 0.027 15.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAU86707.2 - 4.6e-05 22.9 1.5 6.1e-05 22.5 0.8 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EAU86707.2 - 0.00022 20.1 0.1 0.021 13.5 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 EAU86707.2 - 0.0013 17.9 0.4 0.002 17.3 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EAU86707.2 - 0.0029 16.9 0.2 0.056 12.7 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAU86707.2 - 0.019 13.8 1.8 0.17 10.7 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 EAU86707.2 - 0.023 13.7 0.4 0.19 10.8 0.4 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 EAU86708.2 - 1.4e-21 76.9 50.7 4.6e-18 65.3 23.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_M PF02770.19 EAU86709.2 - 0.001 19.2 0.0 0.0031 17.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EAU86709.2 - 0.0014 18.9 0.1 0.0029 17.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HTH_24 PF13412.6 EAU86709.2 - 0.16 11.5 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PHD PF00628.29 EAU86710.2 - 0.00013 21.8 0.9 0.00013 21.8 0.9 2.8 3 0 0 3 3 3 1 PHD-finger Hydantoinase_B PF02538.14 EAU86711.2 - 8.9e-210 697.5 0.5 1e-209 697.3 0.5 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase WH1 PF00568.23 EAU86712.1 - 3.9e-20 71.8 0.0 5.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 EAU86712.1 - 7.7e-06 26.2 0.0 1.9e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 EAU86712.1 - 0.025 14.4 0.1 0.025 14.4 0.1 1.8 2 0 0 2 2 2 0 WH2 motif GMC_oxred_N PF00732.19 EAU86715.2 - 1.3e-68 231.5 0.0 1.7e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU86715.2 - 7.1e-34 117.4 0.0 1.2e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU86715.2 - 2.4e-05 24.5 1.0 5.7e-05 23.3 0.1 2.3 2 1 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU86715.2 - 7.3e-05 22.5 0.7 0.0041 16.8 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAU86715.2 - 0.00026 20.2 0.1 0.034 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EAU86715.2 - 0.00097 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein TrkA_N PF02254.18 EAU86715.2 - 0.0013 19.0 0.1 0.0039 17.4 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 EAU86715.2 - 0.0027 17.0 0.0 0.0058 15.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAU86715.2 - 0.0058 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.14 EAU86715.2 - 0.098 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EAU86715.2 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EAU86715.2 - 0.14 12.7 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU86715.2 - 0.15 12.0 0.1 0.45 10.5 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding zf-C2H2 PF00096.26 EAU86716.1 - 3.5e-09 36.6 20.4 2.1e-05 24.7 1.9 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU86716.1 - 2.8e-06 27.7 16.7 0.0004 21.0 0.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU86716.1 - 2.1e-05 24.7 13.4 0.05 14.1 1.5 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 EAU86716.1 - 0.00034 20.3 12.7 0.051 13.3 0.4 3.7 3 1 0 3 3 3 2 C2H2-type zinc-finger domain OrsD PF12013.8 EAU86716.1 - 0.0016 18.8 10.9 0.061 13.8 0.2 3.4 2 1 1 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D GAGA PF09237.11 EAU86716.1 - 0.017 14.9 1.6 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 GAGA factor zf-C2H2_jaz PF12171.8 EAU86716.1 - 0.054 13.8 1.2 0.088 13.1 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EAU86716.1 - 0.17 11.7 2.3 1.9 8.3 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EAU86716.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 EAU86716.1 - 0.69 10.6 8.4 8.8 7.0 1.7 3.5 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-Di19 PF05605.12 EAU86716.1 - 1.2 9.5 7.6 0.92 9.9 1.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EAU86716.1 - 2.7 8.1 9.5 1.6 8.8 0.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 EAU86716.1 - 3.3 7.8 12.0 0.81 9.8 0.8 2.5 2 1 1 3 3 3 0 BED zinc finger VHS PF00790.19 EAU86719.1 - 8.6e-39 132.6 0.0 5.4e-38 130.0 0.0 2.2 3 0 0 3 3 3 1 VHS domain GAT PF03127.14 EAU86719.1 - 5.7e-22 77.8 0.2 8e-21 74.1 0.0 2.6 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 EAU86719.1 - 0.0037 16.8 0.1 0.011 15.4 0.1 1.8 1 0 0 1 1 1 1 GGA N-GAT domain GATase PF00117.28 EAU86721.1 - 4.5e-12 46.1 0.0 1.4e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAU86721.1 - 0.056 13.2 1.9 0.14 11.9 0.4 2.2 2 1 0 2 2 2 0 Peptidase C26 HTS PF04204.16 EAU86721.1 - 0.063 12.2 0.0 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 Homoserine O-succinyltransferase GATase_3 PF07685.14 EAU86721.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNARE PF05739.19 EAU86722.2 - 4.9e-07 29.7 0.1 7.8e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 SNARE domain KxDL PF10241.9 EAU86722.2 - 0.039 14.2 0.6 11 6.3 0.2 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein DEC-1_N PF04625.13 EAU86722.2 - 9.6 5.1 12.1 1.8 7.5 8.2 1.5 1 1 0 2 2 2 0 DEC-1 protein, N-terminal region Hydrophobin PF01185.18 EAU86723.2 - 7.5e-27 93.8 14.5 9.3e-27 93.5 14.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin NADH_B2 PF14813.6 EAU86724.2 - 0.0026 17.5 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 EBP PF05241.12 EAU86724.2 - 0.083 12.4 9.7 0.15 11.5 9.7 1.5 1 1 0 1 1 1 0 Emopamil binding protein NADH_B2 PF14813.6 EAU86726.1 - 0.012 15.4 2.4 0.014 15.2 0.5 1.9 2 0 0 2 2 2 0 NADH dehydrogenase 1 beta subcomplex subunit 2 EBP PF05241.12 EAU86726.1 - 0.056 12.9 8.4 0.089 12.2 8.4 1.4 1 1 0 1 1 1 0 Emopamil binding protein SSF PF00474.17 EAU86727.1 - 8.7e-18 64.4 30.3 8.7e-18 64.4 30.3 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family zf-C2H2 PF00096.26 EAU86731.2 - 1.6e-10 40.8 13.6 3e-05 24.2 1.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU86731.2 - 6.1e-08 32.7 13.8 0.0015 18.9 0.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU86731.2 - 5.7e-06 26.7 11.3 0.00026 21.6 0.9 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EAU86731.2 - 5.6e-05 22.8 15.6 0.0029 17.3 0.5 3.9 3 1 0 3 3 3 2 C2H2-type zinc-finger domain OrsD PF12013.8 EAU86731.2 - 0.0015 18.9 5.6 0.63 10.5 0.2 3.3 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_jaz PF12171.8 EAU86731.2 - 0.066 13.5 0.9 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EAU86731.2 - 0.096 13.0 2.5 0.16 12.3 2.5 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon SPT_ssu-like PF11779.8 EAU86732.1 - 5e-14 51.7 10.1 7.3e-14 51.1 10.1 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like zf-C2H2 PF00096.26 EAU86733.1 - 8.2e-08 32.3 17.6 7.1e-05 23.0 2.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EAU86733.1 - 9e-05 22.1 9.8 0.014 15.1 0.4 3.8 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EAU86733.1 - 0.00016 22.2 14.2 0.0057 17.4 1.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU86733.1 - 0.00029 21.1 20.9 0.0018 18.6 1.7 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EAU86733.1 - 0.012 15.6 0.5 0.012 15.6 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EAU86733.1 - 0.17 11.7 3.7 0.19 11.5 0.7 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Pox_G9-A16 PF03003.16 EAU86733.1 - 0.37 10.5 4.0 0.65 9.7 4.0 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 FOXP-CC PF16159.5 EAU86733.1 - 0.48 11.1 1.8 24 5.6 0.1 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain OrsD PF12013.8 EAU86733.1 - 2 8.9 8.8 3 8.3 0.3 3.5 1 1 2 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-met PF12874.7 EAU86733.1 - 3.3 8.2 5.0 1.2 9.6 0.8 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type SPT_ssu-like PF11779.8 EAU86734.1 - 1.5e-09 37.3 8.3 2.3e-09 36.7 8.3 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like S4 PF01479.25 EAU86735.2 - 1.4e-09 37.5 0.0 2.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EAU86735.2 - 0.0012 18.6 0.1 0.0053 16.5 0.0 2.0 2 0 0 2 2 2 1 S4 domain Prot_ATP_ID_OB PF16450.5 EAU86735.2 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain WD40 PF00400.32 EAU86737.2 - 1.1e-85 279.3 29.7 8e-09 36.0 0.1 9.6 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU86737.2 - 2.6e-32 110.9 0.0 0.12 12.6 0.0 9.5 1 1 8 9 9 9 9 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU86737.2 - 8.7e-29 100.5 21.1 0.0027 16.7 0.0 9.2 1 1 7 9 9 9 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAU86737.2 - 4e-16 58.5 9.8 3.6 7.6 0.0 9.5 9 0 0 9 9 9 6 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EAU86737.2 - 2.8e-15 56.8 15.6 0.092 12.5 0.1 8.4 1 1 6 7 7 7 5 Lipoprotein LpqB beta-propeller domain NACHT PF05729.12 EAU86737.2 - 1.9e-07 31.2 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain CBM_5_12 PF02839.14 EAU86737.2 - 6.1e-07 29.7 10.3 65 4.4 0.2 8.8 9 0 0 9 9 9 0 Carbohydrate binding domain Hanta_G2 PF01561.16 EAU86737.2 - 1.1e-05 24.3 2.2 7.9 5.0 0.0 5.8 3 1 4 7 7 7 1 Hantavirus glycoprotein G2 AAA_16 PF13191.6 EAU86737.2 - 5.4e-05 23.6 0.7 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain CHAP PF05257.16 EAU86737.2 - 0.0019 18.7 8.7 20 5.8 0.1 7.2 4 1 4 8 8 8 0 CHAP domain HGWP PF03578.15 EAU86737.2 - 0.048 13.2 0.7 0.17 11.4 0.7 2.0 1 0 0 1 1 1 0 HGWP repeat E3_UbLigase_R4 PF13764.6 EAU86737.2 - 0.049 11.8 0.7 0.073 11.2 0.7 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Torsin PF06309.11 EAU86737.2 - 0.091 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin Apolipoprotein PF01442.18 EAU86737.2 - 0.13 12.1 5.0 0.22 11.4 5.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain APS_kinase PF01583.20 EAU86737.2 - 0.14 12.0 0.0 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase KfrA_N PF11740.8 EAU86737.2 - 0.58 10.8 2.6 1.2 9.9 2.6 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term KOW PF00467.29 EAU86737.2 - 1.6 8.8 6.1 63 3.7 0.1 5.0 6 0 0 6 6 6 0 KOW motif AAA_23 PF13476.6 EAU86737.2 - 3.2 8.2 5.0 11 6.4 2.1 2.2 2 0 0 2 2 2 0 AAA domain Nbas_N PF15492.6 EAU86737.2 - 7.4 5.8 10.9 69 2.6 0.3 5.9 5 2 1 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Ferric_reduct PF01794.19 EAU86738.1 - 7.4e-22 77.8 9.4 1.6e-21 76.7 9.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EAU86738.1 - 1.6e-12 47.5 0.0 3.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EAU86738.1 - 3.1e-10 40.4 0.0 2e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain WD40 PF00400.32 EAU86743.2 - 1.6e-07 31.9 0.3 0.088 13.7 0.0 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 EAU86743.2 - 8.4e-06 25.6 2.8 0.00011 22.1 0.4 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EAU86743.2 - 0.0058 16.5 0.4 0.046 13.6 0.0 2.4 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EAU86743.2 - 0.0083 16.4 0.1 1.9 8.8 0.0 3.4 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain NAT PF04768.13 EAU86745.1 - 2.8e-44 150.8 0.0 4.5e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 EAU86745.1 - 4.8e-27 95.1 0.0 1.1e-26 93.9 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 EAU86745.1 - 8.5e-22 77.9 0.0 2.1e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EAU86745.1 - 0.087 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Arm PF00514.23 EAU86745.1 - 0.22 11.6 0.4 25 5.1 0.0 3.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Col_cuticle_N PF01484.17 EAU86747.1 - 0.043 13.9 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain LANC_like PF05147.13 EAU86748.2 - 1.5e-29 102.7 0.0 2.5e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Glyoxal_oxid_N PF07250.11 EAU86749.1 - 3.7e-29 101.6 0.3 6.1e-14 51.8 0.1 4.9 3 1 2 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EAU86749.1 - 6e-21 74.5 0.2 1.6e-20 73.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 EAU86749.1 - 0.0072 16.3 6.7 0.043 13.8 0.1 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain Podoplanin PF05808.11 EAU86749.1 - 0.029 14.5 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 Podoplanin DUF5122 PF17164.4 EAU86749.1 - 0.13 12.6 5.6 29 5.1 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller Lactonase PF10282.9 EAU86750.2 - 1e-35 123.7 0.0 1.1e-35 123.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DAZAP2 PF11029.8 EAU86750.2 - 0.069 14.1 0.1 0.12 13.3 0.1 1.4 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Lactonase PF10282.9 EAU86751.1 - 2.3e-37 129.1 0.0 2.6e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Gpr1_Fun34_YaaH PF01184.19 EAU86752.1 - 2.5e-72 242.8 16.6 3.2e-72 242.5 16.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CoA_binding_3 PF13727.6 EAU86752.1 - 0.094 12.7 1.2 0.16 12.0 1.2 1.4 1 0 0 1 1 1 0 CoA-binding domain Glyco_transf_90 PF05686.12 EAU86753.2 - 2.4e-19 69.5 0.1 4.2e-17 62.1 0.0 2.4 3 0 0 3 3 3 2 Glycosyl transferase family 90 Profilin PF00235.19 EAU86754.1 - 1.8e-42 144.6 0.2 2e-42 144.4 0.2 1.0 1 0 0 1 1 1 1 Profilin AfaD PF05775.12 EAU86754.1 - 0.034 14.6 0.1 0.042 14.3 0.1 1.2 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein MbeD_MobD PF04899.12 EAU86755.1 - 0.23 11.6 0.1 0.23 11.6 0.1 4.1 3 1 2 5 5 5 0 MbeD/MobD like Fib_alpha PF08702.10 EAU86755.1 - 2.1 8.5 10.9 15 5.8 0.2 3.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 EAU86755.1 - 2.7 7.4 47.2 2 7.8 7.7 4.2 2 1 2 4 4 4 0 Golgin subfamily A member 5 TACC_C PF05010.14 EAU86755.1 - 3.7 7.3 20.9 0.32 10.7 8.8 3.5 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PspB PF06667.12 EAU86755.1 - 9 6.4 7.7 14 5.8 1.4 3.6 2 1 1 3 3 3 0 Phage shock protein B LPP PF04728.13 EAU86755.1 - 9.7 6.7 11.6 10 6.6 1.7 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper F-box PF00646.33 EAU86757.2 - 1.2e-05 25.1 1.5 1.2e-05 25.1 1.5 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAU86757.2 - 0.00012 21.8 1.4 0.00029 20.7 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EAU86757.2 - 0.063 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 F-box L51_S25_CI-B8 PF05047.16 EAU86759.1 - 1.4e-10 40.9 0.0 1.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.18 EAU86759.1 - 0.099 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain RGS PF00615.19 EAU86760.1 - 1.3e-09 38.4 1.0 0.00013 22.3 0.3 2.7 2 1 0 2 2 2 2 Regulator of G protein signaling domain EF-hand_1 PF00036.32 EAU86762.2 - 7.6e-31 103.3 7.1 8.3e-10 37.5 0.1 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EAU86762.2 - 7.2e-28 96.2 4.3 2e-13 49.9 0.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 EAU86762.2 - 4.9e-26 91.0 1.1 2e-16 60.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAU86762.2 - 1.3e-19 68.4 4.7 3.1e-09 36.0 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EAU86762.2 - 1.5e-19 68.6 6.2 8e-07 28.3 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EAU86762.2 - 5.1e-10 39.5 0.2 0.0002 21.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAU86762.2 - 1.3e-07 31.5 1.3 0.00048 20.1 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAU86762.2 - 5.6e-06 26.6 0.1 0.00097 19.4 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EAU86762.2 - 7.7e-05 23.5 0.0 0.0058 17.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EAU86762.2 - 0.00016 21.6 0.0 1.2 9.3 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 EAU86762.2 - 0.00051 20.2 3.0 0.019 15.1 0.3 2.7 1 1 2 3 3 3 1 Dockerin type I domain EFhand_Ca_insen PF08726.10 EAU86762.2 - 0.0029 17.7 0.1 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF5580 PF17743.1 EAU86762.2 - 0.007 15.0 0.0 0.008 14.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF1103 PF06513.11 EAU86762.2 - 0.023 14.3 1.0 0.031 13.9 1.0 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 EAU86762.2 - 0.031 14.1 1.5 0.18 11.7 0.7 2.0 1 1 1 2 2 2 0 SurA N-terminal domain DUF3349 PF11829.8 EAU86762.2 - 0.052 14.3 0.5 6 7.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) MotA_activ PF09114.10 EAU86762.2 - 0.07 13.3 0.1 0.24 11.6 0.1 1.7 1 1 1 2 2 2 0 Transcription factor MotA, activation domain DUF5132 PF17195.4 EAU86762.2 - 0.073 13.2 1.2 13 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Spore_III_AB PF09548.10 EAU86762.2 - 0.095 12.8 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) dCache_2 PF08269.11 EAU86762.2 - 0.11 11.7 0.1 7.7 5.6 0.0 2.4 1 1 1 3 3 3 0 Cache domain SPX PF03105.19 EAU86763.2 - 1.9e-53 182.8 1.2 2.6e-53 182.3 1.2 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EAU86763.2 - 4.9e-08 32.7 6.4 8.3e-08 32.0 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU86763.2 - 4.2e-07 30.0 7.1 7.8e-07 29.2 7.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EAU86763.2 - 4.6e-07 29.6 8.3 8.3e-07 28.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU86763.2 - 3.1e-06 26.9 7.3 5.6e-06 26.1 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAU86763.2 - 4.5e-06 26.9 7.8 7.6e-06 26.2 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EAU86763.2 - 0.0001 22.2 7.3 0.0002 21.3 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAU86763.2 - 0.00012 21.8 8.7 0.00021 21.0 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EAU86763.2 - 0.00022 21.0 2.4 0.00044 20.0 2.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EAU86763.2 - 0.00051 20.0 5.6 0.0011 19.0 5.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EAU86763.2 - 0.015 15.6 4.8 0.029 14.7 4.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAU86763.2 - 0.028 14.5 1.3 0.049 13.7 1.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EAU86763.2 - 0.079 13.1 4.2 0.15 12.2 4.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EAU86763.2 - 0.093 12.6 3.4 0.2 11.5 3.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein p450 PF00067.22 EAU86764.1 - 3.2e-65 220.7 0.0 4.1e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Virul_fac_BrkB PF03631.15 EAU86765.1 - 0.11 12.1 6.8 0.18 11.4 6.8 1.3 1 0 0 1 1 1 0 Virulence factor BrkB DUF420 PF04238.12 EAU86765.1 - 0.63 10.3 8.1 0.64 10.3 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF420) TarH PF02203.15 EAU86765.1 - 2 8.3 4.1 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Tar ligand binding domain homologue 4HB_MCP_1 PF12729.7 EAU86765.1 - 6.8 6.2 6.0 2.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction GLE1 PF07817.13 EAU86766.1 - 4.4e-49 167.0 0.0 4.4e-49 167.0 0.0 3.0 3 1 1 4 4 4 1 GLE1-like protein PrmC_N PF17827.1 EAU86767.1 - 3.1e-07 30.9 7.4 6.9 7.3 0.1 5.7 6 0 0 6 6 6 2 PrmC N-terminal domain TFIIIC_sub6 PF10419.9 EAU86767.1 - 0.0003 20.6 0.0 1.3e+02 2.5 0.0 6.4 3 3 3 7 7 7 0 TFIIIC subunit triple barrel domain TRH PF05438.12 EAU86767.1 - 0.0025 17.6 0.0 6.4 6.4 0.0 3.8 1 1 1 3 3 3 1 Thyrotropin-releasing hormone (TRH) U62_UL91 PF17442.2 EAU86767.1 - 0.059 13.4 11.9 10 6.2 0.1 6.4 3 3 5 8 8 8 0 Functional domain of U62 and UL91 proteins ThiS PF02597.20 EAU86767.1 - 0.083 13.5 2.4 2.5e+02 2.4 0.0 5.2 3 2 3 6 6 6 0 ThiS family DUF4238 PF14022.6 EAU86767.1 - 0.1 12.1 1.5 2.3 7.7 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4238) HDV_ag PF01517.18 EAU86767.1 - 0.24 11.2 8.5 8.1 6.2 0.2 4.6 1 1 3 5 5 5 0 Hepatitis delta virus delta antigen VapB_antitoxin PF09957.9 EAU86767.1 - 0.25 11.3 9.4 51 3.9 0.1 5.0 5 0 0 5 5 5 0 Bacterial antitoxin of type II TA system, VapB Skp1 PF01466.19 EAU86767.1 - 0.44 10.7 10.0 62 3.8 0.1 5.8 6 0 0 6 6 6 0 Skp1 family, dimerisation domain PNKP-ligase_C PF16536.5 EAU86767.1 - 1 9.7 5.4 1.6e+02 2.6 0.0 5.1 6 0 0 6 6 6 0 PNKP adenylyltransferase domain, C-terminal region DUF3040 PF11239.8 EAU86767.1 - 1.1 9.5 0.0 1.1 9.5 0.0 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF3040) RHH_4 PF13467.6 EAU86767.1 - 1.4 8.8 3.1 43 4.1 0.1 3.9 3 2 1 4 4 4 0 Ribbon-helix-helix domain DUF2076 PF09849.9 EAU86768.1 - 0.02 14.9 1.6 0.024 14.7 1.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mito_fiss_reg PF05308.11 EAU86768.1 - 0.028 14.5 2.3 0.03 14.4 2.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EAU86768.1 - 0.93 8.9 7.5 1.3 8.5 7.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TonB_N PF16031.5 EAU86768.1 - 8.1 7.0 28.4 12 6.4 28.4 1.2 1 0 0 1 1 1 0 TonB polyproline region PRCC PF10253.9 EAU86769.2 - 4.1 8.1 8.2 6.5 7.5 6.1 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Suc_Fer-like PF06999.12 EAU86770.2 - 1.1e-25 90.7 0.0 1.2e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like ABC_tran PF00005.27 EAU86771.2 - 2.2e-55 186.9 0.3 5.6e-31 107.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAU86771.2 - 2.8e-55 187.9 33.1 3e-29 102.5 14.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EAU86771.2 - 3.4e-11 43.0 3.4 0.0011 18.4 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAU86771.2 - 8.4e-09 35.7 1.8 0.042 13.7 0.1 4.8 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EAU86771.2 - 4.8e-08 33.1 2.2 0.0024 17.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EAU86771.2 - 9.8e-06 25.2 0.1 0.086 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EAU86771.2 - 3.9e-05 23.6 0.5 0.2 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EAU86771.2 - 0.00011 22.3 3.5 0.037 14.1 0.3 2.8 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 EAU86771.2 - 0.00011 22.6 0.6 0.13 12.7 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EAU86771.2 - 0.00019 21.7 1.4 0.13 12.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EAU86771.2 - 0.00039 21.0 4.1 0.14 12.7 0.0 3.3 3 1 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 EAU86771.2 - 0.00054 19.4 0.1 0.73 9.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 EAU86771.2 - 0.00057 19.7 0.7 0.62 9.8 0.3 2.4 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EAU86771.2 - 0.0015 17.8 1.1 1.3 8.3 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin MeaB PF03308.16 EAU86771.2 - 0.0042 16.1 0.4 1.3 8.0 0.1 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 EAU86771.2 - 0.0058 15.8 2.0 0.3 10.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 EAU86771.2 - 0.0091 15.2 0.1 3.3 6.8 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain TrwB_AAD_bind PF10412.9 EAU86771.2 - 0.0092 14.9 0.9 1.4 7.8 0.2 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 EAU86771.2 - 0.0094 16.2 0.4 1.9 8.7 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EAU86771.2 - 0.013 16.0 0.5 8.7 6.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.14 EAU86771.2 - 0.017 14.4 0.0 0.52 9.5 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain cobW PF02492.19 EAU86771.2 - 0.033 13.8 0.8 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EAU86771.2 - 0.041 14.3 0.1 14 6.1 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 EAU86771.2 - 0.044 13.3 0.5 8.5 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EAU86771.2 - 0.053 13.8 0.0 4 7.7 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EAU86771.2 - 0.059 13.1 0.1 5 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 EAU86771.2 - 0.065 12.9 3.8 4.3 7.0 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain ATP-synt_ab PF00006.25 EAU86771.2 - 0.077 12.6 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EAU86771.2 - 0.088 12.7 0.8 14 5.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain MobB PF03205.14 EAU86771.2 - 0.13 12.2 0.7 8.5 6.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 EAU86771.2 - 0.14 12.2 0.3 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 EAU86771.2 - 0.25 11.4 6.0 1.2 9.2 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain RRM_1 PF00076.22 EAU86772.1 - 3.5e-57 190.1 0.0 2.6e-15 56.0 0.0 6.9 6 1 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU86772.1 - 4.6e-12 45.9 0.0 0.00086 19.4 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif RRM_Rrp7 PF17799.1 EAU86772.1 - 0.0035 17.2 0.0 2.5 7.9 0.0 3.0 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain K_channel_TID PF07941.11 EAU86772.1 - 0.48 10.9 5.0 0.11 12.9 0.9 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain UBX PF00789.20 EAU86775.1 - 8e-11 42.0 0.0 5.2e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 EAU86775.1 - 2.4e-05 24.1 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Borrelia_P83 PF05262.11 EAU86775.1 - 0.26 9.7 4.6 0.35 9.3 4.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ank_2 PF12796.7 EAU86776.2 - 1.6e-136 445.2 1.3 8e-14 52.0 0.0 13.7 3 3 11 14 14 14 14 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU86776.2 - 4.8e-98 309.2 24.8 0.0011 19.3 0.0 25.9 27 0 0 27 27 26 20 Ankyrin repeat Ank_4 PF13637.6 EAU86776.2 - 7.5e-95 310.2 15.6 1.5e-11 44.6 0.0 19.1 8 6 10 19 19 19 17 Ankyrin repeats (many copies) Ank PF00023.30 EAU86776.2 - 7.6e-88 285.5 34.8 8.2e-05 22.9 0.0 23.5 22 1 1 23 23 23 20 Ankyrin repeat Ank_5 PF13857.6 EAU86776.2 - 2.2e-74 244.6 39.6 2.1e-07 31.1 0.0 18.8 5 5 17 22 22 22 20 Ankyrin repeats (many copies) VWA_3_C PF18571.1 EAU86776.2 - 3e-05 23.8 3.7 7.3 6.5 0.0 8.3 8 0 0 8 8 8 1 von Willebrand factor type A C-terminal domain NB-ARC PF00931.22 EAU86776.2 - 0.00014 21.1 0.1 0.00029 20.1 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EAU86776.2 - 0.0068 16.3 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU86776.2 - 0.022 15.2 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAU86776.2 - 0.089 13.1 0.0 0.37 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain E3_UbLigase_EDD PF11547.8 EAU86776.2 - 0.32 10.7 4.8 27 4.6 0.5 5.2 5 0 0 5 5 5 0 E3 ubiquitin ligase EDD EF-hand_7 PF13499.6 EAU86777.2 - 1.7e-11 44.4 0.0 1.8e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EAU86777.2 - 4.9e-11 41.6 0.1 0.00012 21.7 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EAU86777.2 - 3e-09 35.8 0.1 0.00032 20.0 0.0 3.5 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EAU86777.2 - 4.2e-06 27.0 0.0 0.0079 16.5 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EAU86777.2 - 0.0003 20.5 0.1 0.0017 18.2 0.1 2.3 3 1 0 3 3 3 1 EF-hand domain pair SapB_1 PF05184.15 EAU86777.2 - 0.0076 16.2 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 2 Saposin-like type B, region 1 EF-hand_11 PF08976.11 EAU86777.2 - 0.028 15.3 0.0 0.047 14.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Thioredoxin_3 PF13192.6 EAU86777.2 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain ExbD PF02472.16 EAU86777.2 - 0.11 12.7 0.0 1.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR DDE_Tnp_IS66_C PF13817.6 EAU86777.2 - 0.13 12.5 0.2 0.41 10.9 0.1 1.8 2 0 0 2 2 2 0 IS66 C-terminal element RSN1_7TM PF02714.15 EAU86779.2 - 2e-53 181.5 27.1 4.1e-29 101.7 9.2 3.3 3 0 0 3 3 3 3 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EAU86779.2 - 1.5e-36 126.3 0.0 2.1e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EAU86779.2 - 4.3e-08 33.1 9.2 6.8e-05 22.7 0.0 4.3 4 0 0 4 4 4 2 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 EAU86779.2 - 0.024 14.4 0.2 0.61 10.0 0.2 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCRF PF03462.18 EAU86782.2 - 1.5e-54 184.8 0.3 3.9e-54 183.5 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EAU86782.2 - 1.3e-35 121.8 3.0 2.8e-35 120.8 3.0 1.5 1 0 0 1 1 1 1 RF-1 domain LRR_4 PF12799.7 EAU86783.2 - 2.5 8.6 4.1 66 4.1 0.1 4.2 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF1744 PF08490.12 EAU86784.2 - 3.3e-135 450.7 0.0 5.9e-135 449.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EAU86784.2 - 8.4e-74 248.7 0.2 1.5e-73 247.8 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EAU86784.2 - 2.3e-11 43.1 0.4 7.2e-08 31.6 0.1 4.1 4 1 0 4 4 4 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EAU86784.2 - 6.9e-07 29.2 0.2 2.4e-06 27.4 0.2 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EAU86784.2 - 0.00057 19.9 0.0 0.0021 18.1 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily zf-C4pol PF14260.6 EAU86784.2 - 0.15 12.6 7.9 0.41 11.1 7.9 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta E1-E2_ATPase PF00122.20 EAU86785.2 - 3.1e-23 82.2 0.3 7.2e-23 81.0 0.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EAU86785.2 - 1.7e-17 64.4 0.0 1.1e-10 42.2 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAU86785.2 - 0.00024 21.1 0.0 0.00052 20.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU86785.2 - 0.0019 18.0 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L38e PF01781.18 EAU86786.1 - 6.9e-34 115.8 1.4 8.1e-34 115.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2344 PF10105.9 EAU86786.1 - 0.076 12.9 0.1 0.18 11.6 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Tetraspanin PF00335.20 EAU86787.1 - 1.3e-05 25.0 5.4 1.3e-05 25.0 5.4 1.5 1 1 0 1 1 1 1 Tetraspanin family Synaptobrevin PF00957.21 EAU86788.1 - 8.5e-15 54.3 1.1 1.4e-14 53.6 1.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EAU86788.1 - 2.1e-11 43.7 0.0 3.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain An_peroxidase PF03098.15 EAU86789.2 - 8.8e-33 113.7 0.0 2.9e-21 75.6 0.0 3.3 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EAU86789.2 - 3.1e-06 26.2 0.0 7.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 Myosin_head PF00063.21 EAU86790.2 - 1.4e-257 856.3 0.3 4.7e-256 851.3 0.0 2.9 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EAU86790.2 - 7.6e-18 63.8 310.4 1e-12 46.8 154.2 7.2 2 2 3 6 6 6 6 Myosin tail Myosin_N PF02736.19 EAU86790.2 - 2.9e-11 43.0 1.2 6.9e-11 41.8 1.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain APG6_N PF17675.1 EAU86790.2 - 0.00087 19.8 22.9 0.00087 19.8 22.9 16.3 4 3 11 15 15 15 3 Apg6 coiled-coil region AAA_22 PF13401.6 EAU86790.2 - 0.031 14.5 0.0 0.031 14.5 0.0 6.9 7 3 0 7 7 7 0 AAA domain IQ PF00612.27 EAU86790.2 - 0.34 10.8 3.8 0.28 11.1 0.5 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Pkinase PF00069.25 EAU86791.2 - 1.7e-63 214.5 0.0 2.3e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86791.2 - 4.9e-28 98.1 0.0 7.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EAU86791.2 - 2.9e-13 50.3 2.9 8.1e-13 48.9 2.9 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EAU86791.2 - 0.0038 16.2 0.0 0.0058 15.6 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 EAU86791.2 - 0.13 12.5 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 C2 domain MARVEL PF01284.23 EAU86795.2 - 0.00021 21.3 12.6 0.00032 20.7 12.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Sensor PF13796.6 EAU86795.2 - 0.00059 19.9 2.8 0.0011 19.1 2.8 1.4 1 0 0 1 1 1 1 Putative sensor zf-ISL3 PF14690.6 EAU86795.2 - 0.098 13.3 0.0 0.78 10.5 0.0 2.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2070 PF09843.9 EAU86795.2 - 8.6 4.5 9.1 11 4.1 9.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_hydro_18 PF00704.28 EAU86796.2 - 9.8e-57 193.0 7.5 2.9e-56 191.5 7.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 EAU86796.2 - 0.00093 19.7 3.4 0.00093 19.7 3.4 3.5 3 0 0 3 3 3 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 EAU86796.2 - 3.3 7.7 12.2 0.066 13.2 3.2 2.5 2 0 0 2 2 2 0 Cellulose-binding domain Ras PF00071.22 EAU86797.1 - 7.1e-34 116.7 0.3 8.4e-34 116.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU86797.1 - 1.3e-25 89.9 0.4 3e-25 88.8 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU86797.1 - 9.7e-08 31.7 0.1 1.2e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAU86797.1 - 4.5e-07 29.5 0.2 5.7e-07 29.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 EAU86797.1 - 0.01 15.2 0.0 2.2 7.6 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein DLIC PF05783.11 EAU86797.1 - 0.013 14.4 0.2 1.6 7.5 0.0 2.0 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 EAU86797.1 - 0.049 12.8 2.1 0.13 11.4 0.1 2.2 2 1 1 3 3 3 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EAU86797.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase CDH-cyt PF16010.5 EAU86798.2 - 7.1e-49 166.0 0.0 1.1e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_C PF05199.13 EAU86798.2 - 1.3e-18 67.9 0.0 2.8e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EAU86798.2 - 1.1e-16 61.1 0.0 3e-16 59.7 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAU86798.2 - 2.9e-07 29.9 0.1 0.00013 21.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EAU86798.2 - 1.3e-06 28.5 0.1 4.5e-06 26.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU86798.2 - 7.2e-06 25.8 0.2 0.00021 21.0 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU86798.2 - 1.4e-05 24.5 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU86798.2 - 0.0001 21.7 0.0 0.0062 15.8 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EAU86798.2 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAU86798.2 - 0.00022 20.0 0.1 0.00035 19.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EAU86798.2 - 0.00061 19.3 0.1 0.025 13.9 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAU86798.2 - 0.0044 16.3 0.2 0.028 13.7 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU86798.2 - 0.0089 15.1 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EAU86798.2 - 0.1 13.2 0.1 0.32 11.6 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EAU86798.2 - 0.15 11.1 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A V_ATPase_I PF01496.19 EAU86799.2 - 0.44 8.4 1.1 0.5 8.2 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2407 PF10302.9 EAU86799.2 - 0.51 10.9 2.9 0.89 10.1 2.9 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain rRNA_proc-arch PF13234.6 EAU86800.2 - 3.2e-89 299.5 0.0 6.1e-89 298.5 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EAU86800.2 - 1.2e-52 177.9 0.7 2.7e-52 176.8 0.7 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EAU86800.2 - 2.9e-17 63.0 0.0 2.5e-16 60.0 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU86800.2 - 1e-07 32.2 0.0 1e-06 29.1 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAU86800.2 - 0.001 19.4 0.1 0.1 12.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 EAU86800.2 - 0.0015 18.6 0.0 0.0046 17.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EAU86800.2 - 0.0094 15.0 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Catalase PF00199.19 EAU86801.2 - 2.8e-183 609.3 0.1 3.6e-183 609.0 0.1 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EAU86801.2 - 1.1e-16 60.8 0.1 2.4e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribosomal_L14 PF00238.19 EAU86802.2 - 7.4e-35 119.7 0.0 9.2e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Paf67 PF10255.9 EAU86804.1 - 2.9e-166 553.5 0.0 4.9e-166 552.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EAU86804.1 - 0.068 13.3 0.0 0.52 10.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF452 PF04301.13 EAU86819.2 - 0.053 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF452) KASH_CCD PF14662.6 EAU86820.1 - 0.063 13.1 0.2 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH RBP_receptor PF14752.6 EAU86823.1 - 0.011 14.3 0.0 0.013 14.1 0.0 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor JHD PF17811.1 EAU86824.1 - 0.027 15.0 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 Jumonji helical domain DUF659 PF04937.15 EAU86831.2 - 0.0077 16.1 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Tet_JBP PF12851.7 EAU86835.2 - 1.9e-07 30.7 0.0 1.2e-05 24.8 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily zf-C4_ClpX PF06689.13 EAU86835.2 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger GTF2I PF02946.14 EAU86838.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 GTF2I-like repeat HMG_box PF00505.19 EAU86838.1 - 0.028 14.8 0.1 0.59 10.6 0.1 2.6 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU86838.1 - 0.028 15.0 0.4 0.076 13.6 0.4 1.8 1 0 0 1 1 1 0 HMG-box domain Tropomyosin_1 PF12718.7 EAU86839.1 - 0.001 19.2 3.2 0.001 19.2 3.2 3.1 2 1 0 3 3 2 1 Tropomyosin like EzrA PF06160.12 EAU86839.1 - 0.0037 15.5 3.1 0.0061 14.8 3.1 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 EAU86839.1 - 0.0093 16.0 3.4 0.0093 16.0 3.4 3.2 3 1 0 3 3 2 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EAU86839.1 - 0.04 14.0 2.3 0.91 9.6 0.9 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 EAU86839.1 - 0.065 11.9 1.9 0.13 10.9 1.9 1.4 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.21 EAU86839.1 - 0.2 12.2 6.7 0.093 13.2 0.7 3.1 1 1 1 3 3 3 0 Spectrin repeat FlaC_arch PF05377.11 EAU86839.1 - 0.22 11.9 2.7 5.2 7.5 0.6 3.4 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EAU86839.1 - 0.26 10.1 9.3 0.61 8.9 6.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 EAU86839.1 - 0.33 11.3 4.4 8.9 6.7 2.7 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 EAU86839.1 - 0.66 9.2 3.7 1.3 8.3 3.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Nup54 PF13874.6 EAU86839.1 - 0.73 9.9 7.0 1.8 8.7 6.4 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FUSC PF04632.12 EAU86839.1 - 1.4 7.3 7.2 1.2 7.6 5.9 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 EAU86839.1 - 2.1 8.6 19.8 0.021 15.1 9.8 2.6 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 EAU86839.1 - 3 8.1 8.9 7.5 6.8 7.8 2.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 EAU86839.1 - 3.2 8.0 4.5 58 4.0 1.3 3.8 3 1 0 3 3 3 0 Haemolysin XhlA V_ATPase_I PF01496.19 EAU86839.1 - 4.6 5.0 14.0 0.0096 13.9 2.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family UBM PF14377.6 EAU86840.2 - 0.023 14.2 0.7 0.14 11.6 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin binding region Ank_2 PF12796.7 EAU86841.2 - 1.8e-117 384.2 2.3 3.4e-13 50.0 0.0 10.9 1 1 10 12 12 12 11 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU86841.2 - 4.6e-93 293.9 8.1 7.9e-05 22.8 0.0 20.7 20 0 0 20 20 20 19 Ankyrin repeat Ank_4 PF13637.6 EAU86841.2 - 3.5e-78 257.0 23.6 4.8e-07 30.2 0.1 17.3 4 2 15 19 19 19 19 Ankyrin repeats (many copies) Ank PF00023.30 EAU86841.2 - 3.7e-70 229.5 26.5 4e-05 23.9 0.1 19.8 19 0 0 19 19 19 17 Ankyrin repeat Ank_5 PF13857.6 EAU86841.2 - 1.2e-60 200.8 35.9 3.2e-07 30.5 0.3 15.7 2 2 15 18 18 18 17 Ankyrin repeats (many copies) NapD PF03927.13 EAU86841.2 - 3.7e-12 46.1 6.7 7.3 6.7 0.0 10.9 6 4 5 12 12 12 3 NapD protein Putative_PNPOx PF01243.20 EAU86841.2 - 0.0024 18.0 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF3325 PF11804.8 EAU86841.2 - 4 7.7 11.6 9.3 6.5 0.2 5.1 5 1 1 6 6 6 0 Protein of unknown function (DUF3325) AAA_12 PF13087.6 EAU86842.2 - 2e-50 171.2 0.0 3.4e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU86842.2 - 2.3e-32 112.8 3.7 1.5e-17 64.2 0.0 3.4 3 1 1 4 4 4 2 AAA domain Dna2 PF08696.11 EAU86842.2 - 1.7e-17 64.0 0.0 3.1e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_30 PF13604.6 EAU86842.2 - 2e-14 53.8 0.0 8.2e-14 51.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU86842.2 - 2.5e-10 40.8 0.0 5.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU86842.2 - 2.8e-06 27.2 0.1 1.3 8.7 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EAU86842.2 - 1.5e-05 25.5 0.0 8.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Helicase_RecD PF05127.14 EAU86842.2 - 0.00068 19.5 0.0 0.0065 16.3 0.0 2.2 1 1 0 1 1 1 1 Helicase Cas_Cas4 PF01930.17 EAU86842.2 - 0.001 19.2 0.1 0.021 14.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF83 ResIII PF04851.15 EAU86842.2 - 0.0039 17.2 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EAU86842.2 - 0.0044 16.6 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 EAU86842.2 - 0.011 15.4 0.2 0.028 14.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EAU86842.2 - 0.011 15.0 0.1 0.03 13.6 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.22 EAU86842.2 - 0.015 14.9 0.2 0.028 14.0 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain CbiA PF01656.23 EAU86842.2 - 0.016 15.3 0.0 0.087 12.9 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EAU86842.2 - 0.018 15.2 0.3 0.2 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAU86842.2 - 0.059 13.4 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EAU86842.2 - 0.081 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAU86842.2 - 0.11 12.0 0.1 0.34 10.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAU86842.2 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 EAU86842.2 - 0.14 12.7 0.1 0.3 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EAU86842.2 - 0.17 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 EAU86842.2 - 0.22 11.9 1.3 0.52 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_L24e PF01246.20 EAU86843.1 - 4.1e-30 103.8 0.2 4.1e-30 103.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e EF-hand_1 PF00036.32 EAU86845.2 - 2.6e-43 142.4 11.5 4e-10 38.5 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAU86845.2 - 1.9e-36 124.3 2.4 1.5e-18 67.0 0.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAU86845.2 - 4.5e-33 112.9 10.5 1e-13 50.9 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EAU86845.2 - 6.3e-32 106.8 5.9 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAU86845.2 - 2.4e-28 96.3 7.7 1.6e-06 27.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EAU86845.2 - 2.6e-16 59.7 0.1 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAU86845.2 - 1.3e-10 41.1 0.7 3.2e-05 23.8 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EAU86845.2 - 9.1e-09 35.6 0.0 0.00093 19.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EAU86845.2 - 9.9e-07 28.7 0.2 0.042 13.9 0.0 3.4 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EAU86845.2 - 2.4e-05 25.1 0.0 0.016 16.1 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 EAU86845.2 - 5.6e-05 23.1 1.0 0.00027 21.0 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 EAU86845.2 - 0.00016 21.8 5.1 0.023 14.9 0.6 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF1103 PF06513.11 EAU86845.2 - 0.00038 20.2 1.2 0.00043 20.0 1.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 EAU86845.2 - 0.00041 20.3 0.4 0.43 10.5 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 EAU86845.2 - 0.0018 19.0 0.2 1.5 9.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) TerB PF05099.13 EAU86845.2 - 0.0022 18.0 0.2 0.48 10.4 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.16 EAU86845.2 - 0.0025 18.0 0.1 0.46 10.7 0.0 3.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 EAU86845.2 - 0.0029 18.1 0.0 1.1 9.8 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) MotA_activ PF09114.10 EAU86845.2 - 0.0048 17.0 0.4 0.078 13.1 0.0 2.3 1 1 0 2 2 2 1 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.16 EAU86845.2 - 0.0051 17.1 0.4 3.2 8.1 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF5580 PF17743.1 EAU86845.2 - 0.0061 15.1 0.0 0.0061 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 EAU86845.2 - 0.01 16.2 0.1 4.8 7.6 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 EAU86845.2 - 0.016 15.1 0.5 1 9.2 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 EAU86845.2 - 0.059 13.0 0.2 0.1 12.3 0.2 1.5 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF1811 PF08838.10 EAU86845.2 - 0.063 13.5 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) Spore_III_AB PF09548.10 EAU86845.2 - 0.067 13.3 0.4 0.14 12.2 0.4 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HGTP_anticodon PF03129.20 EAU86846.1 - 3e-23 81.8 0.1 6.6e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EAU86846.1 - 2.4e-09 37.4 0.0 1.7e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4199 PF13858.6 EAU86847.1 - 0.078 13.4 0.5 0.18 12.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SseC PF04888.12 EAU86847.1 - 0.1 12.2 0.2 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family YqfD PF06898.11 EAU86847.1 - 0.37 9.6 2.6 0.42 9.4 2.6 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD PRANC PF09372.10 EAU86856.1 - 0.024 14.9 0.0 0.049 14.0 0.0 1.4 2 0 0 2 2 2 0 PRANC domain MFS_1 PF07690.16 EAU86868.2 - 4.4e-22 78.5 41.5 4.4e-22 78.5 41.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Putative_PNPOx PF01243.20 EAU86871.2 - 1.4e-05 25.2 0.0 2.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Bestrophin PF01062.21 EAU86873.1 - 3e-32 112.2 5.0 1.7e-22 80.2 0.1 2.3 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel APG12 PF04110.13 EAU86877.2 - 9.9e-30 102.8 0.0 1.2e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EAU86877.2 - 0.029 14.5 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like SUI1 PF01253.22 EAU86878.1 - 7.3e-23 80.9 0.5 1.4e-22 80.0 0.5 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 EAU86878.1 - 0.025 14.6 0.2 0.041 13.8 0.2 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Ank_2 PF12796.7 EAU86880.2 - 2.7e-85 281.1 3.9 4.3e-12 46.5 0.1 7.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EAU86880.2 - 1.6e-64 211.7 27.2 1.6e-06 28.3 0.1 14.3 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.6 EAU86880.2 - 1.7e-64 206.1 15.1 0.00066 19.9 0.0 15.8 15 0 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.6 EAU86880.2 - 1.6e-58 194.3 13.5 8e-10 39.1 0.1 10.5 6 3 5 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU86880.2 - 8.9e-40 134.2 28.2 1.9e-05 24.9 0.0 13.0 2 2 11 13 13 13 12 Ankyrin repeats (many copies) NB-ARC PF00931.22 EAU86880.2 - 0.00049 19.4 0.0 0.00086 18.6 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EAU86880.2 - 0.0073 16.2 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Acetyltransf_1 PF00583.25 EAU86882.2 - 3.1e-13 50.0 0.0 5.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU86882.2 - 3.3e-08 33.5 0.0 7.8e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU86882.2 - 3.5e-06 27.4 0.1 5.9e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GHL6 PF14871.6 EAU86882.2 - 0.036 14.2 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Pox_Ag35 PF03286.14 EAU86887.2 - 0.092 12.5 3.6 0.22 11.3 3.6 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDDD PF10161.9 EAU86888.1 - 0.38 10.5 2.6 1.5 8.7 2.6 2.0 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Ribosomal_60s PF00428.19 EAU86894.2 - 0.05 14.2 0.3 0.05 14.2 0.3 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Fzo_mitofusin PF04799.13 EAU86897.2 - 0.0027 17.3 1.0 0.0043 16.6 1.0 1.2 1 0 0 1 1 1 1 fzo-like conserved region Exonuc_VII_L PF02601.15 EAU86897.2 - 0.091 12.3 0.9 0.13 11.8 0.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HR1 PF02185.16 EAU86897.2 - 5.6 7.2 9.5 10 6.3 0.3 2.7 1 1 1 2 2 2 0 Hr1 repeat CxC4 PF18717.1 EAU86898.2 - 7.6e-46 155.2 0.0 1.6e-45 154.1 0.0 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EAU86898.2 - 0.011 15.4 0.2 0.017 14.8 0.2 1.2 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase VP_N-CPKC PF11475.8 EAU86898.2 - 0.027 14.3 0.1 0.092 12.7 0.1 1.9 1 0 0 1 1 1 0 Virion protein N terminal domain ABC_tran PF00005.27 EAU86903.2 - 1.7e-19 70.7 0.0 3.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU86903.2 - 2.8e-06 27.3 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EAU86903.2 - 0.00044 20.7 0.1 0.0055 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EAU86903.2 - 0.00082 19.1 0.1 0.002 17.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EAU86903.2 - 0.0033 17.2 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EAU86903.2 - 0.012 16.2 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EAU86903.2 - 0.026 14.0 0.4 0.057 12.8 0.3 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EAU86903.2 - 0.029 13.9 0.0 0.069 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAU86903.2 - 0.031 14.4 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EAU86903.2 - 0.037 13.9 0.1 0.063 13.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EAU86903.2 - 0.044 13.7 0.1 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EAU86903.2 - 0.046 14.0 0.0 0.076 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU86903.2 - 0.088 13.4 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EAU86903.2 - 0.095 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 EAU86903.2 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.6 EAU86903.2 - 0.12 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EAU86903.2 - 0.22 10.3 0.1 0.96 8.2 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Med8 PF10232.9 EAU86904.2 - 0.0056 16.3 0.8 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 YL1 PF05764.13 EAU86904.2 - 0.13 12.4 3.5 0.19 11.8 3.5 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EAU86904.2 - 0.23 9.6 6.9 0.29 9.3 6.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAU86904.2 - 0.35 9.1 3.5 0.42 8.8 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EAU86904.2 - 0.38 10.1 6.8 0.51 9.6 6.8 1.1 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 EAU86904.2 - 0.65 9.8 4.5 0.99 9.2 4.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CobT PF06213.12 EAU86904.2 - 0.74 9.1 11.3 1.1 8.6 11.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 EAU86904.2 - 1.6 8.0 11.6 2.3 7.5 11.6 1.1 1 0 0 1 1 1 0 NOA36 protein His_Phos_2 PF00328.22 EAU86905.2 - 0.00083 18.8 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) RII_binding_1 PF10522.9 EAU86905.2 - 0.22 11.8 0.1 0.58 10.5 0.1 1.6 1 0 0 1 1 1 0 RII binding domain DivIC PF04977.15 EAU86908.2 - 0.027 14.2 0.8 0.57 10.0 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator IHABP4_N PF16174.5 EAU86908.2 - 0.45 11.1 2.9 1.2 9.8 2.9 1.6 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF1258 PF06869.12 EAU86909.2 - 9.5e-05 22.0 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) DUF4218 PF13960.6 EAU86909.2 - 0.00038 20.1 0.0 0.00082 19.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.14 EAU86909.2 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 ABC_tran PF00005.27 EAU86911.2 - 3.3e-21 76.2 0.0 5.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU86911.2 - 5.7e-08 32.9 0.1 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU86911.2 - 1.6e-05 24.4 0.0 0.01 15.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAU86911.2 - 0.00063 19.6 0.0 0.00063 19.6 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 EAU86911.2 - 0.00068 19.3 0.2 0.0014 18.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU86911.2 - 0.0029 18.0 0.0 0.0059 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EAU86911.2 - 0.01 16.3 0.2 0.02 15.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain DLIC PF05783.11 EAU86911.2 - 0.021 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 EAU86911.2 - 0.051 13.5 0.2 0.096 12.6 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 EAU86911.2 - 0.068 12.0 0.1 0.63 8.8 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 EAU86911.2 - 0.072 13.4 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAU86911.2 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAU86911.2 - 0.095 12.6 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain UPF0139 PF03669.13 EAU86912.1 - 0.67 9.9 2.5 1.6 8.7 2.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Aconitase PF00330.20 EAU86914.2 - 3.5e-156 520.8 0.1 4.4e-156 520.5 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EAU86914.2 - 1.2e-44 151.8 0.0 2.3e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain HMG_box_2 PF09011.10 EAU86918.1 - 1.2e-11 45.0 14.3 6.8e-08 33.0 1.2 3.1 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 EAU86918.1 - 2.1e-09 37.6 21.0 0.0001 22.6 8.2 4.0 2 2 0 2 2 2 2 HMG (high mobility group) box Protamine_like PF06382.11 EAU86918.1 - 0.61 10.3 3.9 1.1 9.4 0.3 2.3 1 1 0 2 2 2 0 Protamine and protamine like GP67 PF17634.2 EAU86920.2 - 0.016 15.6 0.5 0.025 15.0 0.5 1.3 1 0 0 1 1 1 0 Gene product 67 PI-PLC-X PF00388.19 EAU86921.2 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain ABC_tran PF00005.27 EAU86922.2 - 3.1e-22 79.6 0.0 5.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAU86922.2 - 3.4e-06 26.6 0.1 0.089 12.2 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAU86922.2 - 5.7e-06 26.4 0.1 0.00029 20.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAU86922.2 - 0.00038 20.2 0.3 0.0016 18.1 0.2 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EAU86922.2 - 0.0017 18.1 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EAU86922.2 - 0.019 15.5 0.1 0.037 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EAU86922.2 - 0.038 12.7 0.0 0.096 11.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EAU86922.2 - 0.057 12.2 0.4 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 EAU86922.2 - 0.058 13.9 0.2 0.16 12.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU86922.2 - 0.076 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAU86922.2 - 0.082 13.1 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAU86922.2 - 0.083 13.3 0.1 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EAU86922.2 - 0.096 12.6 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 EAU86922.2 - 0.11 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF1887 PF09002.11 EAU86922.2 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) FtsK_SpoIIIE PF01580.18 EAU86922.2 - 0.16 11.3 0.2 0.32 10.3 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family p450 PF00067.22 EAU86925.2 - 1.8e-68 231.4 0.0 2.4e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spermine_synth PF01564.17 EAU86927.2 - 3.1e-07 30.0 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Blt1_C PF17183.4 EAU86927.2 - 0.13 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain IGPS PF00218.21 EAU86928.2 - 2e-79 266.3 0.1 3.1e-79 265.7 0.1 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EAU86928.2 - 1.9e-14 53.9 0.0 3.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.19 EAU86928.2 - 0.0002 21.2 0.2 0.00079 19.2 0.1 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 EAU86928.2 - 0.0096 15.1 0.1 0.018 14.2 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 EAU86928.2 - 0.027 13.7 0.6 0.21 10.7 0.1 2.4 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Pantoate_ligase PF02569.15 EAU86929.1 - 0.13 11.5 0.2 14 4.8 0.0 3.2 3 1 1 4 4 4 0 Pantoate-beta-alanine ligase Rx_N PF18052.1 EAU86930.2 - 0.019 15.2 1.2 0.032 14.5 0.7 1.6 2 0 0 2 2 2 0 Rx N-terminal domain GMC_oxred_N PF00732.19 EAU86932.2 - 6.4e-59 199.7 0.0 1.1e-58 198.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU86932.2 - 2.3e-32 112.5 0.0 4.2e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EAU86932.2 - 1.2e-06 28.0 0.1 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU86932.2 - 3.1e-06 27.0 0.7 2.4e-05 24.1 0.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAU86932.2 - 5.6e-06 25.6 0.1 2.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU86932.2 - 7.4e-06 26.1 0.1 0.00013 22.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EAU86932.2 - 4.2e-05 24.0 0.2 0.044 14.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU86932.2 - 0.00015 21.0 0.2 0.00089 18.4 0.0 2.1 2 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EAU86932.2 - 0.00028 20.2 0.0 0.00051 19.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EAU86932.2 - 0.0011 18.3 0.1 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EAU86932.2 - 0.04 14.2 0.1 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 EAU86932.2 - 0.042 12.7 0.2 0.34 9.7 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 EAU86932.2 - 0.11 11.2 0.1 0.27 9.9 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 EAU86932.2 - 0.39 10.7 2.0 0.93 9.5 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 EAU86933.2 - 7.6e-63 212.6 0.0 1e-62 212.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU86933.2 - 1.1e-23 84.3 0.0 2.5e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EAU86933.2 - 5.5e-06 25.7 0.0 9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU86933.2 - 6.7e-05 23.0 0.1 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU86933.2 - 0.00012 21.4 0.2 0.0013 17.9 0.0 2.3 2 1 1 3 3 3 1 FAD binding domain Thi4 PF01946.17 EAU86933.2 - 0.00033 20.0 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAU86933.2 - 0.0011 18.6 0.3 0.0047 16.6 0.0 2.1 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU86933.2 - 0.0042 16.4 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU86933.2 - 0.011 16.3 0.0 0.15 12.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EAU86933.2 - 0.039 14.2 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 EAU86933.2 - 0.23 10.1 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein TFIIIC_delta PF12657.7 EAU86934.2 - 3.4e-16 59.7 0.0 8.5e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EAU86934.2 - 7.6e-13 48.3 0.1 2.5e-10 40.2 0.1 2.5 2 0 0 2 2 2 2 Putative zinc-finger of transcription factor IIIC complex PAP2 PF01569.21 EAU86935.2 - 4.3e-14 52.4 10.3 4.3e-13 49.2 10.3 2.2 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EAU86935.2 - 0.0011 19.1 0.1 0.29 11.3 0.0 2.9 3 0 0 3 3 3 1 Divergent PAP2 family DUF3082 PF11282.8 EAU86935.2 - 0.014 15.7 0.6 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) Peptidase_M54 PF07998.11 EAU86935.2 - 0.13 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 Polysacc_synt_C PF14667.6 EAU86935.2 - 2.3 8.3 11.7 0.079 13.0 5.3 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF1772 PF08592.11 EAU86935.2 - 2.5 8.4 7.5 0.18 12.1 2.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 EAU86939.2 - 7.5e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86939.2 - 0.073 12.3 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 EAU86940.2 - 0.00024 20.6 0.0 0.00045 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86940.2 - 0.015 14.6 0.0 0.1 11.9 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU86940.2 - 0.046 12.5 0.0 0.45 9.2 0.0 1.9 1 1 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 EAU86942.2 - 2.4e-05 23.9 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86942.2 - 0.0038 16.5 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAU86942.2 - 0.0053 16.7 0.1 0.0088 16.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MAP65_ASE1 PF03999.12 EAU86943.2 - 1.9e-72 244.9 2.1 7.7e-68 229.7 0.3 2.3 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) NUFIP1 PF10453.9 EAU86943.2 - 0.12 12.2 0.6 0.44 10.4 0.6 1.9 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Exonuc_VII_L PF02601.15 EAU86943.2 - 2.3 7.7 8.5 4 6.9 0.1 2.6 2 1 0 2 2 2 0 Exonuclease VII, large subunit FIT1_2 PF17357.2 EAU86944.1 - 1.9 8.7 11.1 0.35 11.0 5.5 2.4 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 Tetraspanin PF00335.20 EAU86947.2 - 6.4 6.4 7.1 17 5.1 7.4 1.7 1 1 0 1 1 1 0 Tetraspanin family F-box-like PF12937.7 EAU86948.2 - 1e-08 34.9 1.2 2.2e-08 33.9 1.2 1.6 1 0 0 1 1 1 1 F-box-like AAA PF00004.29 EAU86949.2 - 1.2e-19 71.1 0.0 2.2e-09 37.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU86949.2 - 0.00014 22.3 0.0 0.0004 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain BCS1_N PF08740.11 EAU86949.2 - 0.00062 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal RuvB_N PF05496.12 EAU86949.2 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EAU86949.2 - 0.0081 15.4 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_11 PF13086.6 EAU86949.2 - 0.046 13.5 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAU86949.2 - 0.054 13.5 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EAU86949.2 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EAU86949.2 - 0.16 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tfb5 PF06331.12 EAU86950.1 - 1.8e-25 88.7 0.6 1.9e-25 88.6 0.6 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Binary_toxB_3 PF17476.2 EAU86950.1 - 0.035 14.3 0.1 0.041 14.0 0.1 1.0 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 DUF2554 PF10829.8 EAU86950.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) DUF3906 PF13046.6 EAU86950.1 - 0.13 12.4 0.6 6 7.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3906) Rib_5-P_isom_A PF06026.14 EAU86951.1 - 1.8e-60 203.5 0.0 2.3e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) EPSP_synthase PF00275.20 EAU86952.2 - 1.8e-111 372.8 0.0 2.8e-111 372.2 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EAU86952.2 - 4.7e-100 334.1 0.0 1e-99 333.0 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EAU86952.2 - 1e-52 179.7 0.0 1.8e-52 178.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EAU86952.2 - 1.9e-27 96.4 0.0 1.9e-26 93.1 0.0 2.5 2 1 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EAU86952.2 - 5.7e-25 87.4 0.0 4.6e-24 84.5 0.0 2.6 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EAU86952.2 - 4.7e-08 32.6 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EAU86952.2 - 7.6e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EAU86952.2 - 1.9e-05 24.7 0.0 4.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 EAU86952.2 - 0.036 14.4 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Sacchrp_dh_NADP PF03435.18 EAU86952.2 - 0.12 12.7 1.5 11 6.3 0.0 3.3 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain Pkinase_Tyr PF07714.17 EAU86953.2 - 0.0011 18.3 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU86953.2 - 0.002 17.5 0.1 0.0075 15.7 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Lactonase PF10282.9 EAU86955.1 - 1.7e-15 57.1 0.2 3.7e-15 56.0 0.1 1.5 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.21 EAU86956.1 - 3.2e-08 33.2 0.0 1.1e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Dioxygenase VWA PF00092.28 EAU86957.1 - 8.7e-11 42.4 0.0 3.3e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAU86957.1 - 1.2e-07 32.3 0.0 6.2e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Med25_VWA PF11265.8 EAU86957.1 - 5.6e-06 26.3 0.0 2.2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A Band_7 PF01145.25 EAU86957.1 - 0.019 15.0 0.2 0.019 15.0 0.2 1.5 2 0 0 2 2 2 0 SPFH domain / Band 7 family Integrin_beta PF00362.18 EAU86957.1 - 0.028 14.1 0.0 0.064 12.9 0.0 1.6 1 1 0 1 1 1 0 Integrin beta chain VWA domain COG4 PF08318.12 EAU86957.1 - 0.12 11.5 0.8 0.17 10.9 0.8 1.2 1 0 0 1 1 1 0 COG4 transport protein Pkinase_Tyr PF07714.17 EAU86958.2 - 0.0026 17.1 0.4 0.0075 15.6 0.1 1.7 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EAU86958.2 - 0.19 11.1 0.7 0.29 10.4 0.2 1.5 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 EAU86959.2 - 6.6e-05 22.3 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU86959.2 - 0.00053 19.4 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Spore_III_AB PF09548.10 EAU86961.2 - 0.13 12.4 0.3 5.1 7.2 0.0 2.5 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) TPR_1 PF00515.28 EAU86965.1 - 4e-12 45.4 0.5 0.0032 17.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU86965.1 - 1.1e-11 43.8 2.1 0.00043 20.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU86965.1 - 7.9e-11 41.5 2.5 6.6e-05 22.5 0.1 3.5 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 EAU86965.1 - 8.2e-07 28.8 2.0 0.00076 19.5 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU86965.1 - 0.0023 18.5 1.5 2.6 8.8 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU86965.1 - 0.0069 17.1 0.6 5.2 8.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Sec8_exocyst PF04048.14 EAU86965.1 - 0.016 15.1 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TPR_12 PF13424.6 EAU86965.1 - 0.017 15.4 1.8 3.8 7.9 0.1 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU86965.1 - 0.12 12.5 1.3 0.65 10.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EAU86965.1 - 0.29 11.2 1.1 5.7 7.1 0.1 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Nrap_D4 PF17405.2 EAU86967.1 - 3e-57 193.4 0.0 5.2e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 EAU86967.1 - 1.7e-40 138.7 0.0 5e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D2 PF17403.2 EAU86967.1 - 5.3e-38 130.2 0.0 6.7e-37 126.6 0.0 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 EAU86967.1 - 1.3e-37 129.2 0.2 2e-37 128.6 0.2 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 EAU86967.1 - 2.9e-32 111.7 0.0 8.6e-32 110.2 0.0 1.8 2 0 0 2 2 2 1 Nrap protein domain 6 Nrap_D5 PF17406.2 EAU86967.1 - 5.9e-25 87.9 0.0 1.5e-23 83.4 0.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 APH PF01636.23 EAU86968.2 - 2.9e-09 37.2 0.1 7.6e-09 35.8 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA4 PF13093.6 EAU86969.2 - 0.0019 18.1 4.3 0.0038 17.1 4.3 1.4 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APH PF01636.23 EAU86971.2 - 0.011 15.6 0.2 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.14 EAU86971.2 - 1.2 7.3 7.3 1.7 6.9 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 EAU86972.2 - 3.6 6.3 5.5 4.6 6.0 5.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-RVT PF13966.6 EAU86973.2 - 1e-05 26.1 0.8 2.2e-05 25.1 0.8 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF444 PF04285.12 EAU86974.1 - 0.22 10.6 0.3 0.31 10.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) YIF1 PF03878.15 EAU86975.2 - 1.8e-88 296.1 0.6 2.2e-88 295.8 0.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EAU86975.2 - 0.00013 21.7 1.9 0.00025 20.8 1.9 1.4 1 0 0 1 1 1 1 Yip1 domain DUF3301 PF11743.8 EAU86976.1 - 0.02 14.6 0.3 0.03 14.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Mo25 PF08569.11 EAU86979.2 - 1.4e-134 448.6 2.6 1.6e-134 448.4 2.6 1.0 1 0 0 1 1 1 1 Mo25-like Pyr_redox_2 PF07992.14 EAU86980.1 - 1.2e-29 103.5 0.0 1.7e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU86980.1 - 3.5e-13 49.9 0.0 7.1e-11 42.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU86980.1 - 3.3e-07 30.4 0.8 0.32 11.0 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EAU86980.1 - 0.0019 17.5 0.0 0.0099 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU86980.1 - 0.0027 17.4 9.5 2.5 7.6 0.0 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EAU86980.1 - 0.003 16.3 0.5 0.45 9.2 0.0 3.3 4 0 0 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.12 EAU86980.1 - 0.0037 16.4 0.1 2.8 6.9 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein Thi4 PF01946.17 EAU86980.1 - 0.011 15.0 0.0 1.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 EAU86980.1 - 0.011 14.6 1.6 0.71 8.7 0.0 3.2 4 0 0 4 4 4 0 Tryptophan halogenase GIDA PF01134.22 EAU86980.1 - 0.015 14.4 0.7 30 3.5 0.1 3.5 4 1 0 4 4 4 0 Glucose inhibited division protein A TrkA_N PF02254.18 EAU86980.1 - 0.016 15.4 0.1 4.8 7.5 0.0 2.7 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 EAU86980.1 - 0.017 14.3 0.0 3.3 6.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EAU86980.1 - 0.022 15.2 0.0 3 8.3 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EAU86980.1 - 0.14 12.4 0.2 4.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain MatE PF01554.18 EAU86983.2 - 0.0078 15.9 21.9 0.078 12.6 2.0 3.7 4 0 0 4 4 4 3 MatE Glyco_hydro_61 PF03443.14 EAU86984.1 - 1.4e-52 178.7 0.0 1.9e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pyr_redox_2 PF07992.14 EAU86985.1 - 1.6e-36 126.1 0.1 2.1e-36 125.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU86985.1 - 5.2e-17 62.2 0.1 4.2e-13 49.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU86985.1 - 4.3e-07 29.5 0.4 1.5e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU86985.1 - 1.1e-06 28.7 0.7 0.55 10.2 0.0 3.6 3 1 1 4 4 4 3 FAD-NAD(P)-binding DAO PF01266.24 EAU86985.1 - 8e-06 25.7 1.7 0.3 10.6 0.0 3.8 3 1 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 EAU86985.1 - 7e-05 22.2 0.1 0.37 10.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Trp_halogenase PF04820.14 EAU86985.1 - 9.4e-05 21.4 0.7 0.065 12.1 0.0 3.5 4 0 0 4 4 4 1 Tryptophan halogenase TrkA_N PF02254.18 EAU86985.1 - 0.00042 20.6 0.1 0.28 11.4 0.0 2.8 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 EAU86985.1 - 0.0023 18.3 0.6 0.065 13.7 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EAU86985.1 - 0.0028 16.8 0.0 5.7 5.9 0.0 3.7 3 1 1 4 4 4 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU86985.1 - 0.01 16.0 0.3 0.31 11.3 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EAU86985.1 - 0.032 13.3 0.6 3.8 6.5 0.0 3.0 4 0 0 4 4 4 0 Glucose inhibited division protein A HI0933_like PF03486.14 EAU86985.1 - 0.065 11.9 2.1 18 3.9 0.1 3.8 3 1 0 4 4 4 0 HI0933-like protein K_oxygenase PF13434.6 EAU86985.1 - 0.088 11.9 0.0 1.8 7.6 0.0 2.3 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EAU86985.1 - 0.12 11.5 0.1 0.74 9.0 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain F-box-like PF12937.7 EAU86986.1 - 1.3e-07 31.4 0.3 4e-07 29.8 0.3 2.0 1 0 0 1 1 1 1 F-box-like Utp14 PF04615.13 EAU86990.2 - 0.17 10.4 26.2 0.26 9.8 26.2 1.2 1 0 0 1 1 1 0 Utp14 protein KDZ PF18758.1 EAU86991.2 - 2.2e-48 164.8 0.0 3.7e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU86991.2 - 4.4e-27 94.3 0.8 3.3e-25 88.3 0.8 2.5 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 EAU86991.2 - 2.4e-07 30.9 0.1 5.9e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin LRR_4 PF12799.7 EAU86995.2 - 8.1 7.0 7.1 52 4.5 0.0 4.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) GCM PF03615.15 EAU87004.2 - 5.1e-10 39.4 1.4 1e-09 38.4 1.4 1.5 1 0 0 1 1 1 1 GCM motif protein Na_Ca_ex PF01699.24 EAU87006.1 - 2.4e-37 128.2 30.8 1.1e-18 67.6 11.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ctr PF04145.15 EAU87006.1 - 0.65 10.6 2.7 21 5.7 0.1 2.9 2 1 0 2 2 2 0 Ctr copper transporter family ThiF PF00899.21 EAU87007.2 - 3e-09 36.6 0.0 1.9e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 ThiF family TPR_MLP1_2 PF07926.12 EAU87009.2 - 0.0014 18.7 10.0 0.0042 17.1 10.0 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Rab5-bind PF09311.11 EAU87009.2 - 0.0034 16.8 8.5 0.0034 16.8 8.5 1.8 1 1 1 2 2 2 1 Rabaptin-like protein IFT57 PF10498.9 EAU87009.2 - 0.0039 16.2 6.8 0.0057 15.7 6.8 1.3 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 UPF0242 PF06785.11 EAU87009.2 - 0.0047 17.1 11.0 0.0067 16.6 11.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TRPM_tetra PF16519.5 EAU87009.2 - 0.014 15.5 2.3 0.014 15.5 2.3 2.3 1 1 1 2 2 2 0 Tetramerisation domain of TRPM Tmemb_cc2 PF10267.9 EAU87009.2 - 0.016 14.4 10.1 0.044 12.9 10.1 1.6 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Exonuc_VII_L PF02601.15 EAU87009.2 - 0.023 14.3 5.7 0.029 13.9 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1043 PF06295.12 EAU87009.2 - 0.024 14.6 1.3 0.037 14.0 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Taxilin PF09728.9 EAU87009.2 - 0.025 13.7 13.6 0.038 13.2 13.6 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF1664 PF07889.12 EAU87009.2 - 0.027 14.5 8.2 0.49 10.5 2.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) HSBP1 PF06825.12 EAU87009.2 - 0.033 14.0 2.6 0.13 12.2 1.1 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 EAU87009.2 - 0.039 14.0 0.1 0.8 9.7 0.1 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC144C PF14915.6 EAU87009.2 - 0.041 13.0 16.5 0.053 12.6 5.7 2.0 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region DUF713 PF05218.14 EAU87009.2 - 0.043 13.5 2.0 0.23 11.2 2.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF713) MbeD_MobD PF04899.12 EAU87009.2 - 0.052 13.7 0.2 2.7 8.2 0.1 2.4 2 0 0 2 2 2 0 MbeD/MobD like COG2 PF06148.11 EAU87009.2 - 0.072 13.2 12.4 0.21 11.7 10.2 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Golgin_A5 PF09787.9 EAU87009.2 - 0.073 12.5 13.3 0.099 12.1 13.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 YtxH PF12732.7 EAU87009.2 - 0.085 13.4 0.8 0.69 10.5 0.8 2.3 1 1 0 1 1 1 0 YtxH-like protein YscO PF07321.12 EAU87009.2 - 0.088 12.8 15.8 0.14 12.1 2.6 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO Laminin_II PF06009.12 EAU87009.2 - 0.089 12.8 5.6 0.66 10.0 3.0 2.5 1 1 2 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.9 EAU87009.2 - 0.095 13.0 5.1 3.8 7.9 4.7 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Macoilin PF09726.9 EAU87009.2 - 0.11 11.1 6.5 0.13 10.8 6.5 1.0 1 0 0 1 1 1 0 Macoilin family TMPIT PF07851.13 EAU87009.2 - 0.12 11.6 6.7 2.2 7.5 1.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF4795 PF16043.5 EAU87009.2 - 0.13 11.9 10.1 0.19 11.3 10.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) AAA_13 PF13166.6 EAU87009.2 - 0.17 10.5 5.1 0.21 10.2 5.1 1.1 1 0 0 1 1 1 0 AAA domain DUF2802 PF10975.8 EAU87009.2 - 0.2 11.8 6.6 0.26 11.4 1.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2802) Atg14 PF10186.9 EAU87009.2 - 0.24 10.4 6.7 0.33 10.0 6.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 EAU87009.2 - 0.25 10.7 15.2 1.4 8.2 15.2 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Nup54 PF13874.6 EAU87009.2 - 0.27 11.3 10.0 0.79 9.8 1.4 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 KxDL PF10241.9 EAU87009.2 - 0.3 11.4 5.7 7.5 6.9 0.7 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein CCDC53 PF10152.9 EAU87009.2 - 0.39 11.1 3.6 2.5 8.5 0.6 2.2 1 1 0 2 2 2 0 Subunit CCDC53 of WASH complex ADIP PF11559.8 EAU87009.2 - 0.42 10.7 12.4 0.89 9.6 4.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 EAU87009.2 - 0.42 9.1 8.3 0.62 8.6 8.2 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 EAU87009.2 - 0.43 10.8 14.4 0.15 12.3 6.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 EAU87009.2 - 0.45 10.9 9.7 0.22 11.9 4.4 2.9 1 1 1 2 2 2 0 Csm1 N-terminal domain XhlA PF10779.9 EAU87009.2 - 0.46 10.7 24.2 0.76 10.0 3.0 4.1 2 1 3 5 5 4 0 Haemolysin XhlA CdvA PF18822.1 EAU87009.2 - 0.49 10.2 12.2 1.8 8.4 4.1 2.7 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DLP_helical PF18709.1 EAU87009.2 - 0.5 9.5 6.1 0.23 10.6 1.8 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain Spc7 PF08317.11 EAU87009.2 - 0.52 9.1 14.2 1.3 7.9 14.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Vac_Fusion PF02346.16 EAU87009.2 - 0.56 9.9 9.9 0.76 9.5 3.0 3.1 1 1 2 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Noelin-1 PF12308.8 EAU87009.2 - 0.58 10.2 4.2 3.7 7.6 0.4 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein Matrilin_ccoil PF10393.9 EAU87009.2 - 0.59 10.0 4.4 1.3 8.9 0.4 2.8 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin V_ATPase_I PF01496.19 EAU87009.2 - 0.6 8.0 5.1 0.79 7.6 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 EAU87009.2 - 0.67 10.1 11.8 1.2 9.2 2.7 3.3 2 1 1 3 3 3 0 bZIP transcription factor CENP-Q PF13094.6 EAU87009.2 - 0.74 10.0 13.4 1.2 9.3 13.4 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Snapin_Pallidin PF14712.6 EAU87009.2 - 0.88 10.0 6.1 2.2 8.8 3.4 2.4 1 1 1 2 2 2 0 Snapin/Pallidin Fib_alpha PF08702.10 EAU87009.2 - 1.1 9.5 6.8 8.6 6.5 1.2 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AKNA PF12443.8 EAU87009.2 - 1.7 9.4 6.4 1.9 9.2 1.5 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor DUF812 PF05667.11 EAU87009.2 - 2 7.2 13.2 4.1 6.2 13.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Spectrin PF00435.21 EAU87009.2 - 2.2 8.8 10.6 34 5.0 0.8 2.2 1 1 1 2 2 2 0 Spectrin repeat DUF4446 PF14584.6 EAU87009.2 - 2.6 8.0 7.0 4.5 7.3 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) EMP24_GP25L PF01105.24 EAU87009.2 - 2.7 7.9 8.3 3.1 7.7 0.7 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF16 PF01519.16 EAU87009.2 - 2.8 8.5 10.2 4.2 7.9 9.2 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF2730 PF10805.8 EAU87009.2 - 2.9 8.0 8.2 11 6.1 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DivIC PF04977.15 EAU87009.2 - 3 7.7 10.4 10 6.0 0.1 3.2 1 1 2 3 3 3 0 Septum formation initiator CREPT PF16566.5 EAU87009.2 - 3.3 7.9 8.4 1.8 8.8 3.7 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour FlaC_arch PF05377.11 EAU87009.2 - 3.7 8.0 13.0 3.2 8.2 0.8 3.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EAU87009.2 - 3.7 8.2 9.9 25 5.6 1.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA FAM76 PF16046.5 EAU87009.2 - 5 6.4 8.6 18 4.6 8.6 1.8 1 1 0 1 1 1 0 FAM76 protein Cauli_AT PF03233.13 EAU87009.2 - 5.1 7.0 8.6 7.4 6.5 2.2 2.6 1 1 1 2 2 2 0 Aphid transmission protein DUF4337 PF14235.6 EAU87009.2 - 5.8 7.0 5.2 28 4.8 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Seryl_tRNA_N PF02403.22 EAU87009.2 - 6.3 7.1 13.8 7.8 6.8 4.6 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GMC_oxred_C PF05199.13 EAU87010.1 - 1.4e-33 116.5 0.0 2.2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EAU87010.1 - 2.3e-25 89.6 0.0 3.3e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EAU87011.2 - 3.1e-34 118.7 0.0 3.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EAU87011.2 - 2.8e-06 26.6 0.1 3.7e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU87011.2 - 7.2e-05 22.9 0.0 0.0002 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU87011.2 - 0.00016 21.4 0.0 0.00054 19.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU87011.2 - 0.00084 18.7 0.0 0.00098 18.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU87011.2 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAU87011.2 - 0.0014 17.9 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 EAU87011.2 - 0.014 15.7 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 EAU87011.2 - 0.041 13.9 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EAU87011.2 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EAU87011.2 - 0.15 10.8 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EAU87011.2 - 0.23 10.7 0.1 0.34 10.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Hydrolase_4 PF12146.8 EAU87012.2 - 3.7e-13 49.3 0.0 1.9e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAU87012.2 - 9.3e-11 41.9 0.1 4e-09 36.5 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU87012.2 - 4.7e-06 27.4 0.0 7.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EAU87012.2 - 0.00019 21.4 0.0 0.018 15.0 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EAU87012.2 - 0.00019 21.3 0.1 0.18 11.6 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 EAU87012.2 - 0.0025 17.4 0.0 0.079 12.5 0.0 2.7 3 1 0 3 3 3 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EAU87012.2 - 0.0042 16.7 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EAU87012.2 - 0.0068 15.9 0.0 0.043 13.3 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EAU87012.2 - 0.0098 14.6 0.2 1.5 7.4 0.2 2.3 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EAU87012.2 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.16 EAU87012.2 - 0.058 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Methyltransf_2 PF00891.18 EAU87013.2 - 2.6e-10 40.0 0.0 3.9e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 O-methyltransferase domain FeoB_associated PF12669.7 EAU87014.2 - 0.014 15.8 2.2 0.023 15.1 2.2 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein RIC3 PF15361.6 EAU87014.2 - 0.027 14.9 0.0 0.039 14.4 0.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 TNFR_16_TM PF18422.1 EAU87014.2 - 0.21 11.6 0.6 0.36 10.8 0.6 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain TSNAXIP1_N PF15739.5 EAU87015.1 - 0.00042 20.6 7.6 0.00042 20.6 7.6 2.2 1 1 2 3 3 3 1 Translin-associated factor X-interacting N-terminus FAM184 PF15665.5 EAU87015.1 - 0.0046 16.8 21.8 0.0048 16.7 9.1 2.5 1 1 1 2 2 2 2 Family with sequence similarity 184, A and B Gp-FAR-1 PF05823.12 EAU87015.1 - 0.0047 17.3 3.4 0.0047 17.3 3.4 1.8 2 0 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FliD_C PF07195.12 EAU87015.1 - 0.0087 15.5 0.8 0.0087 15.5 0.8 2.4 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Focal_AT PF03623.13 EAU87015.1 - 0.01 15.8 2.9 0.01 15.8 2.9 3.0 1 1 2 3 3 3 0 Focal adhesion targeting region PLC-beta_C PF08703.10 EAU87015.1 - 0.01 15.8 12.2 0.01 15.8 12.2 2.4 1 1 0 2 2 2 0 PLC-beta C terminal DUF2362 PF10154.9 EAU87015.1 - 0.018 14.0 9.6 0.026 13.5 9.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Gp49 PF05973.14 EAU87015.1 - 0.03 14.4 2.0 0.98 9.6 0.2 2.6 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) TPR_MLP1_2 PF07926.12 EAU87015.1 - 0.048 13.7 23.2 0.23 11.5 8.2 3.3 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Nbs1_C PF08599.10 EAU87015.1 - 0.073 13.2 0.1 0.073 13.2 0.1 2.6 3 0 0 3 3 2 0 DNA damage repair protein Nbs1 Fib_alpha PF08702.10 EAU87015.1 - 0.14 12.4 15.3 2.9 8.1 9.0 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Apolipoprotein PF01442.18 EAU87015.1 - 0.16 11.9 26.4 0.21 11.4 19.4 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EAU87015.1 - 0.23 11.7 5.8 0.13 12.6 1.0 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EAU87015.1 - 0.34 11.0 9.7 4.9 7.2 0.8 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2587 PF10759.9 EAU87015.1 - 0.35 10.4 5.9 0.17 11.4 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2587) Cor1 PF04803.12 EAU87015.1 - 0.39 10.9 9.2 0.59 10.3 6.6 2.8 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region HAUS6_N PF14661.6 EAU87015.1 - 2.4 7.7 18.3 1.3 8.5 9.6 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus YlqD PF11068.8 EAU87015.1 - 2.7 8.4 10.8 6.9 7.0 6.9 2.9 1 1 1 2 2 2 0 YlqD protein DUF1664 PF07889.12 EAU87015.1 - 3.1 7.9 13.9 5.9 6.9 1.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF1993 PF09351.10 EAU87015.1 - 3.2 7.9 6.4 1.1 9.3 2.4 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) Bacillus_HBL PF05791.11 EAU87015.1 - 3.3 7.5 7.3 1.7 8.4 2.7 2.5 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 EAU87015.1 - 4.5 6.6 16.9 8.5 5.6 16.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YtxH PF12732.7 EAU87015.1 - 7 7.3 7.0 3.6e+02 1.8 7.0 3.2 1 1 0 1 1 1 0 YtxH-like protein GvpL_GvpF PF06386.11 EAU87015.1 - 9.7 6.0 21.5 7.5 6.4 8.5 2.1 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF ZnuA PF01297.17 EAU87016.2 - 0.015 14.7 2.4 0.023 14.1 2.2 1.5 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Arena_nucleocap PF00843.17 EAU87016.2 - 0.021 13.8 1.1 0.031 13.2 1.1 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain PspA_IM30 PF04012.12 EAU87016.2 - 0.043 13.4 9.7 0.18 11.3 9.7 1.8 1 1 0 1 1 1 0 PspA/IM30 family Baculo_PEP_C PF04513.12 EAU87016.2 - 0.12 12.4 1.8 6.2 6.9 0.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CtIP_N PF10482.9 EAU87016.2 - 0.17 11.9 9.0 0.099 12.7 5.6 2.0 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain FliD_C PF07195.12 EAU87016.2 - 0.19 11.1 3.4 0.19 11.2 0.7 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Antigen_Bd37 PF11641.8 EAU87016.2 - 0.45 10.0 5.3 0.94 8.9 5.3 1.6 1 1 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein SPATA1_C PF15743.5 EAU87016.2 - 0.46 10.5 8.3 0.23 11.5 5.5 1.7 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus Apolipoprotein PF01442.18 EAU87016.2 - 0.59 10.0 13.4 1.9 8.3 13.4 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 EAU87016.2 - 0.82 9.9 6.2 1.4 9.1 1.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ApoLp-III PF07464.11 EAU87016.2 - 1.3 9.1 5.4 8.8 6.4 1.3 3.3 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) YlqD PF11068.8 EAU87016.2 - 2.3 8.6 7.3 10 6.5 2.1 2.6 1 1 1 2 2 2 0 YlqD protein CENP-H PF05837.12 EAU87016.2 - 6.3 7.2 12.4 11 6.5 0.7 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 EAU87016.2 - 9.6 5.7 9.6 15 5.0 9.6 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit GMC_oxred_N PF00732.19 EAU87019.2 - 4.2e-39 134.7 0.0 1.8e-37 129.4 0.0 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87019.2 - 8.6e-32 110.6 0.0 1.7e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAU87019.2 - 2.3e-07 30.3 0.0 0.0016 17.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EAU87019.2 - 1.5e-05 24.3 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU87019.2 - 0.00017 21.7 0.0 0.00082 19.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU87019.2 - 0.00071 19.3 0.3 0.0027 17.3 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EAU87019.2 - 0.0044 16.3 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EAU87019.2 - 0.028 13.7 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EAU87019.2 - 0.084 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.27 EAU87019.2 - 0.12 13.0 0.1 1.9 9.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU87019.2 - 0.15 12.1 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Metallophos PF00149.28 EAU87021.2 - 3.8e-34 119.0 0.0 5.8e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF658 PF04936.12 EAU87021.2 - 0.091 12.5 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Skp1_POZ PF03931.15 EAU87022.2 - 0.00066 19.8 0.0 0.0021 18.2 0.0 2.0 1 1 1 2 2 2 1 Skp1 family, tetramerisation domain F-box-like PF12937.7 EAU87029.1 - 2.1e-10 40.3 0.4 5.7e-10 38.9 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU87029.1 - 0.0088 15.9 0.3 0.8 9.7 0.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 EAU87029.1 - 0.099 13.1 0.2 0.65 10.5 0.2 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU87030.1 - 3.8e-08 33.1 0.4 7.8e-08 32.1 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU87030.1 - 0.0005 19.9 1.3 0.005 16.7 1.3 2.4 1 1 0 1 1 1 1 F-box domain Band_7 PF01145.25 EAU87031.1 - 4.2e-25 88.8 2.0 4.4e-25 88.7 0.1 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EAU87031.1 - 0.00094 18.9 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF3080 PF11279.8 EAU87031.1 - 0.0038 16.5 4.4 0.0038 16.5 4.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3080) Glyco_hydro_47 PF01532.20 EAU87032.2 - 1.7e-129 432.7 0.0 2.9e-129 432.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 F-box-like PF12937.7 EAU87035.1 - 0.00066 19.5 0.1 0.0019 18.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Sld5 PF05916.11 EAU87036.1 - 0.0046 17.4 0.1 0.0074 16.7 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 EAU87036.1 - 0.014 15.6 0.3 0.028 14.6 0.3 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Castor_Poll_mid PF06241.12 EAU87036.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel MARVEL PF01284.23 EAU87042.1 - 0.0022 18.0 7.4 0.073 13.1 7.4 2.3 1 1 0 1 1 1 1 Membrane-associating domain PRA1 PF03208.19 EAU87042.1 - 2 8.0 11.2 1.3 8.7 8.4 2.1 2 1 0 2 2 2 0 PRA1 family protein DUF4079 PF13301.6 EAU87042.1 - 3.9 7.6 6.4 0.81 9.8 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) DUF2530 PF10745.9 EAU87042.1 - 7.3 6.9 7.1 0.98 9.7 0.7 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) NPL PF17800.1 EAU87044.2 - 4.1e-05 24.1 0.0 4.1e-05 24.1 0.0 2.0 2 1 0 2 2 2 1 Nucleoplasmin-like domain BUD22 PF09073.10 EAU87044.2 - 0.31 10.3 8.3 0.38 10.0 8.3 1.0 1 0 0 1 1 1 0 BUD22 NPL PF17800.1 EAU87045.1 - 0.039 14.5 0.0 0.057 14.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin-like domain PatG_D PF18047.1 EAU87045.1 - 0.093 13.2 0.0 0.19 12.2 0.0 1.3 1 1 0 1 1 1 0 PatG Domain DUF749 PF05370.11 EAU87046.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF749) MOZ_SAS PF01853.18 EAU87047.2 - 0.0099 15.5 0.0 0.041 13.5 0.0 1.9 2 0 0 2 2 2 1 MOZ/SAS family SlyX PF04102.12 EAU87048.2 - 0.0017 18.9 3.1 9.6 6.9 0.1 4.0 3 1 0 3 3 3 1 SlyX BLOC1_2 PF10046.9 EAU87048.2 - 0.031 14.6 3.7 15 6.0 0.0 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EAU87048.2 - 0.042 14.2 9.0 15 6.1 1.7 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EAU87048.2 - 0.17 12.0 4.3 1.9 8.6 0.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 EAU87048.2 - 0.26 11.5 8.4 2.1 8.5 1.6 3.1 3 0 0 3 3 3 0 Tropomyosin like DUF1515 PF07439.11 EAU87048.2 - 0.46 10.5 5.7 4.3 7.4 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) Trimer_CC PF08954.11 EAU87048.2 - 0.61 9.7 5.0 1.8 8.2 0.0 3.3 3 0 0 3 3 3 0 Trimerisation motif HSBP1 PF06825.12 EAU87048.2 - 1 9.3 7.9 1.4 8.9 0.1 4.0 4 0 0 4 4 4 0 Heat shock factor binding protein 1 MAP65_ASE1 PF03999.12 EAU87048.2 - 1.1 7.8 7.0 18 3.8 7.0 2.0 1 1 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DHR10 PF18595.1 EAU87048.2 - 1.4 9.0 6.8 17 5.5 0.3 3.7 3 1 0 4 4 4 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 EAU87048.2 - 2.5 6.9 6.8 1.2 8.0 1.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 EAU87048.2 - 3 8.2 4.9 5.1 7.4 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein YscO-like PF16789.5 EAU87048.2 - 6 6.9 10.4 2.3 8.3 1.7 2.5 2 1 0 3 3 3 0 YscO-like protein AAA_22 PF13401.6 EAU87049.2 - 4e-07 30.4 0.0 3e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU87049.2 - 8.8e-06 25.7 0.0 2.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU87049.2 - 0.009 16.4 0.0 0.05 14.0 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EAU87049.2 - 0.017 14.3 0.0 0.1 11.7 0.0 2.2 2 1 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.9 EAU87049.2 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 EAU87049.2 - 0.14 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 EAU87049.2 - 0.22 11.4 0.2 0.49 10.3 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Ank_2 PF12796.7 EAU87050.2 - 2.8e-74 245.7 12.1 1.3e-12 48.1 0.0 8.7 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU87050.2 - 5.6e-52 173.1 27.4 1.6e-07 31.5 0.1 11.5 6 3 6 12 12 12 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU87050.2 - 1.5e-44 149.8 22.0 3.6e-05 24.2 0.0 14.3 4 4 10 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU87050.2 - 1.2e-39 129.7 7.7 0.00085 19.6 0.0 13.6 15 0 0 15 15 15 9 Ankyrin repeat Ank PF00023.30 EAU87050.2 - 2.4e-35 119.5 16.3 0.007 16.8 0.1 13.3 13 0 0 13 13 13 10 Ankyrin repeat Glyco_hydro_61 PF03443.14 EAU87051.1 - 2.1e-58 197.7 0.0 3e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-MYND PF01753.18 EAU87052.2 - 6.5e-11 42.1 7.0 1.6e-10 40.8 7.0 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU87052.2 - 5.3 7.4 16.2 0.038 14.3 6.7 2.2 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding p450 PF00067.22 EAU87054.2 - 3.5e-64 217.3 0.0 1.3e-63 215.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pre-SET PF05033.16 EAU87055.2 - 1.2e-18 67.7 2.0 1.2e-18 67.7 2.0 2.4 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 EAU87055.2 - 1.3e-11 45.2 2.5 4e-11 43.6 0.5 2.8 2 1 0 2 2 2 1 SET domain UQ_con PF00179.26 EAU87056.2 - 1.7e-20 73.1 0.0 4.1e-20 71.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Hamartin PF04388.12 EAU87056.2 - 7.1 5.2 6.9 8.2 5.0 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein PRCC PF10253.9 EAU87056.2 - 9.3 7.0 12.1 0.27 12.0 5.6 1.7 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Ank_2 PF12796.7 EAU87063.2 - 1.9e-19 70.0 0.8 1.6e-09 38.2 0.0 4.3 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU87063.2 - 1.9e-17 63.1 2.1 2.9e-06 27.5 0.1 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU87063.2 - 2.4e-15 56.7 1.2 0.031 14.9 0.0 5.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAU87063.2 - 3.3e-11 43.1 2.0 0.26 11.8 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EAU87063.2 - 6.5e-10 38.4 2.0 0.0059 17.0 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat NACHT PF05729.12 EAU87063.2 - 6.7e-05 22.9 0.3 0.00047 20.1 0.1 2.3 1 1 1 2 2 2 1 NACHT domain AAA_22 PF13401.6 EAU87063.2 - 0.00019 21.7 0.1 0.00051 20.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain REV PF00424.18 EAU87064.2 - 0.0016 18.5 0.3 0.0035 17.3 0.3 1.5 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) OPT PF03169.15 EAU87065.2 - 6.9e-185 616.2 54.1 7.8e-185 616.1 54.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Beta_helix PF13229.6 EAU87066.1 - 0.00045 20.1 28.7 0.0018 18.1 18.8 2.4 2 1 1 3 3 3 2 Right handed beta helix region Ank_2 PF12796.7 EAU87067.2 - 3.7e-68 226.1 24.3 3.6e-11 43.5 0.4 9.6 2 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU87067.2 - 2.1e-53 178.0 22.7 7.6e-08 32.8 0.2 14.9 6 2 9 15 15 15 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU87067.2 - 2.9e-49 164.5 34.4 8.9e-09 35.5 0.4 13.7 7 3 7 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 EAU87067.2 - 2.1e-37 125.9 23.8 0.008 16.6 0.0 16.8 16 1 0 16 16 16 10 Ankyrin repeat Ank_3 PF13606.6 EAU87067.2 - 3.8e-31 103.6 9.7 0.004 17.5 0.0 15.2 14 1 0 14 14 14 5 Ankyrin repeat AAA_22 PF13401.6 EAU87067.2 - 1.9e-05 24.9 0.0 0.00016 22.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU87067.2 - 5.9e-05 23.0 0.0 0.0002 21.4 0.0 2.0 1 0 0 1 1 1 1 NACHT domain DUF3126 PF11324.8 EAU87067.2 - 0.0022 17.8 0.5 6.5 6.7 0.0 5.2 7 0 0 7 7 7 1 Protein of unknown function (DUF3126) AAA_16 PF13191.6 EAU87067.2 - 0.0028 18.1 0.5 0.059 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain PSK_trans_fac PF07704.11 EAU87067.2 - 0.99 10.2 5.4 6.5 7.6 0.8 3.3 3 0 0 3 3 3 0 Rv0623-like transcription factor Ank_2 PF12796.7 EAU87068.2 - 1.1e-55 186.2 11.0 4.6e-11 43.2 0.2 7.7 2 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU87068.2 - 5.6e-37 125.3 20.4 5.9e-10 39.2 0.1 10.4 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU87068.2 - 7.5e-34 115.7 14.9 2.6e-07 31.0 0.1 11.3 4 3 7 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 EAU87068.2 - 4.1e-31 106.0 8.5 0.00028 21.2 0.0 12.0 11 1 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 EAU87068.2 - 1.8e-25 86.2 3.9 0.0023 18.3 0.0 12.0 13 0 0 13 13 13 5 Ankyrin repeat DUF3126 PF11324.8 EAU87068.2 - 0.011 15.5 0.0 13 5.7 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3126) CorA PF01544.18 EAU87069.2 - 1.8e-12 47.2 9.2 7.5e-12 45.2 9.2 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-MYND PF01753.18 EAU87070.1 - 5.8e-10 39.1 8.4 1.2e-09 38.1 8.4 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 EAU87070.1 - 0.023 15.9 0.2 0.038 15.1 0.2 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-C6H2 PF15801.5 EAU87070.1 - 1.5 9.1 4.2 3.4 8.0 4.2 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding WD40 PF00400.32 EAU87073.2 - 2.6e-06 28.1 5.9 0.039 14.8 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Rav1p_C PF12234.8 EAU87073.2 - 0.057 11.8 0.0 0.089 11.2 0.0 1.3 1 0 0 1 1 1 0 RAVE protein 1 C terminal PD40 PF07676.12 EAU87073.2 - 0.12 12.4 4.3 8.7 6.4 0.2 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-C3HC4 PF00097.25 EAU87075.2 - 4.8e-07 29.5 4.0 1e-06 28.5 1.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU87075.2 - 8.1e-07 28.8 5.7 3.4e-05 23.6 1.7 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU87075.2 - 7.7e-05 22.5 1.9 7.7e-05 22.5 1.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU87075.2 - 0.0001 22.3 3.1 0.00025 21.2 1.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAU87075.2 - 0.0013 18.7 0.5 0.0013 18.7 0.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAU87075.2 - 0.0014 18.5 5.7 0.0056 16.6 1.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAU87075.2 - 0.0017 18.7 6.0 0.0071 16.7 1.7 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EAU87075.2 - 0.0057 16.5 7.2 0.071 13.0 3.0 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EAU87075.2 - 0.31 11.2 3.2 0.23 11.6 1.4 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Zn_Tnp_IS91 PF14319.6 EAU87075.2 - 0.43 10.7 4.5 1.3 9.1 1.9 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF1644 PF07800.12 EAU87075.2 - 0.49 10.4 7.8 0.27 11.3 3.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) ORC6 PF05460.13 EAU87075.2 - 7.8 5.7 14.0 7.5 5.7 12.5 1.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Brr6_like_C_C PF10104.9 EAU87077.1 - 3.3e-28 98.1 0.0 4.2e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF4233 PF14017.6 EAU87080.2 - 0.0069 16.7 1.2 0.0082 16.5 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4233) COX1 PF00115.20 EAU87080.2 - 0.012 14.5 1.6 0.016 14.1 1.6 1.0 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Frag1 PF10277.9 EAU87080.2 - 0.016 14.8 0.5 0.02 14.4 0.5 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF962 PF06127.11 EAU87081.1 - 0.96 9.6 4.2 0.65 10.1 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Phage_holin_3_2 PF04550.12 EAU87082.2 - 0.074 13.6 0.9 0.69 10.5 0.4 2.1 2 0 0 2 2 2 0 Phage holin family 2 Glyco_hydro_47 PF01532.20 EAU87085.1 - 2e-128 429.2 0.1 2.4e-128 428.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Isochorismatase PF00857.20 EAU87087.2 - 1.3e-17 64.5 0.1 2.8e-17 63.5 0.1 1.5 1 1 0 1 1 1 1 Isochorismatase family Spore_GerQ PF09671.10 EAU87087.2 - 0.085 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) F-box-like PF12937.7 EAU87088.2 - 5.3e-08 32.6 4.2 1.2e-07 31.5 4.2 1.6 1 0 0 1 1 1 1 F-box-like Isochorismatase PF00857.20 EAU87089.1 - 1.1e-16 61.5 0.4 4.2e-16 59.6 0.4 1.7 1 1 0 1 1 1 1 Isochorismatase family Chordopox_G3 PF06129.12 EAU87089.1 - 0.17 12.6 0.1 0.32 11.7 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus G3 protein DUF2127 PF09900.9 EAU87090.2 - 0.018 15.3 4.1 0.018 15.3 4.1 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2127) Asp-Al_Ex PF06826.12 EAU87090.2 - 0.027 14.3 0.2 0.065 13.1 0.2 1.6 1 0 0 1 1 1 0 Predicted Permease Membrane Region DUF3671 PF12420.8 EAU87090.2 - 0.88 9.7 3.8 0.65 10.1 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function UPF0016 PF01169.19 EAU87091.1 - 9.1e-45 150.9 20.2 6.3e-24 84.1 6.3 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EAU87091.1 - 0.00027 20.7 9.7 0.0016 18.2 0.2 2.4 2 0 0 2 2 2 2 Putative manganese efflux pump TerC PF03741.16 EAU87091.1 - 0.001 18.8 3.9 0.0039 16.9 0.0 2.6 2 1 0 2 2 2 1 Integral membrane protein TerC family LysE PF01810.18 EAU87091.1 - 0.031 13.7 15.0 0.87 9.0 4.1 3.1 2 1 1 3 3 3 0 LysE type translocator DUF3995 PF13160.6 EAU87091.1 - 0.08 13.3 9.7 0.2 12.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) p450 PF00067.22 EAU87092.1 - 4.9e-66 223.4 0.0 5.9e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos_2 PF12850.7 EAU87095.2 - 3.2e-18 66.5 0.2 4.2e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EAU87095.2 - 0.00028 21.4 1.5 0.21 12.0 0.1 2.4 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase LIME1 PF15332.6 EAU87097.1 - 0.16 11.6 0.5 0.33 10.5 0.2 1.6 1 1 1 2 2 2 0 Lck-interacting transmembrane adapter 1 ArAE_2 PF10334.9 EAU87098.2 - 1.9e-56 191.5 0.0 2.8e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 EAU87098.2 - 5.3e-53 180.7 5.9 6e-52 177.2 4.3 3.1 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EAU87098.2 - 2.2e-07 31.0 16.1 2.2e-07 31.0 16.1 3.4 3 0 0 3 3 3 2 Fusaric acid resistance protein-like FAM176 PF14851.6 EAU87099.2 - 0.28 10.8 0.7 0.86 9.3 0.7 1.7 1 0 0 1 1 1 0 FAM176 family SHR3_chaperone PF08229.11 EAU87100.1 - 0.097 11.6 1.8 1.5 7.8 0.2 2.3 2 1 0 2 2 2 0 ER membrane protein SH3 VKOR PF07884.14 EAU87100.1 - 2.2 8.5 10.6 0.039 14.1 1.7 2.3 3 0 0 3 3 3 0 Vitamin K epoxide reductase family DEAD PF00270.29 EAU87101.1 - 1.3e-23 83.6 0.0 3.9e-23 82.1 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU87101.1 - 1.4e-11 44.7 0.1 1.6e-10 41.3 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU87101.1 - 0.016 15.3 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SHR3_chaperone PF08229.11 EAU87105.2 - 0.024 13.6 3.9 0.55 9.2 0.4 2.6 2 0 0 2 2 2 0 ER membrane protein SH3 DUF2721 PF11026.8 EAU87105.2 - 1.8 8.5 14.0 0.53 10.2 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) FMO-like PF00743.19 EAU87107.2 - 3.5e-30 104.9 0.0 3.5e-19 68.6 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAU87107.2 - 2e-15 56.8 0.0 1e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU87107.2 - 7.4e-13 48.4 0.0 7.2e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU87107.2 - 2.1e-07 31.1 0.0 7.4e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EAU87107.2 - 1.2e-06 28.0 0.1 1.6e-05 24.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EAU87107.2 - 0.00014 21.6 2.0 0.0079 15.8 0.0 2.6 3 1 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EAU87107.2 - 0.0011 18.4 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Catalase_C PF18011.1 EAU87107.2 - 0.012 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases Pyr_redox PF00070.27 EAU87107.2 - 0.042 14.4 0.1 17 6.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EAU87107.2 - 0.063 12.6 0.1 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EAU87107.2 - 0.08 12.2 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EAU87107.2 - 0.12 12.3 0.2 0.84 9.6 0.0 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_2 PF03446.15 EAU87107.2 - 0.13 12.4 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_C54 PF03416.19 EAU87108.2 - 7.8e-98 327.3 0.0 1.1e-97 326.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 K_channel_TID PF07941.11 EAU87108.2 - 0.032 14.7 0.1 0.11 13.0 0.1 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Dam PF05869.11 EAU87109.1 - 0.1 12.2 0.5 0.18 11.3 0.1 1.6 2 0 0 2 2 2 0 DNA N-6-adenine-methyltransferase (Dam) Peptidase_M43 PF05572.13 EAU87110.2 - 7.4e-18 64.9 0.3 1.9e-17 63.6 0.1 1.9 2 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87110.2 - 0.012 15.8 0.2 0.018 15.2 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU87110.2 - 0.017 15.7 0.8 0.066 13.7 0.8 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU87110.2 - 0.075 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PriCT_1 PF08708.11 EAU87110.2 - 0.076 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Reprolysin_2 PF13574.6 EAU87110.2 - 0.1 12.5 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like UCH PF00443.29 EAU87111.2 - 1.1e-37 130.0 0.0 3.1e-37 128.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAU87111.2 - 1.9e-25 89.0 10.0 2e-19 69.7 1.6 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EAU87111.2 - 8.9e-25 86.2 0.1 5.4e-11 42.2 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EAU87111.2 - 1.5e-23 82.3 2.6 1.4e-22 79.2 0.3 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 EAU87111.2 - 1.4e-19 70.9 0.3 8e-19 68.4 0.3 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase C1_2 PF03107.16 EAU87111.2 - 2.3 8.6 10.5 1.2 9.5 2.3 3.7 4 0 0 4 4 4 0 C1 domain zf-C2HE PF16278.5 EAU87111.2 - 4.1 7.9 6.7 2.3 8.7 0.5 3.3 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Aldedh PF00171.22 EAU87113.2 - 5.7e-170 565.8 1.1 2e-169 564.0 1.1 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family ECH_1 PF00378.20 EAU87114.1 - 1.9e-32 112.6 0.2 1e-29 103.6 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAU87114.1 - 3.4e-17 63.0 0.1 2e-16 60.4 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HSP70 PF00012.20 EAU87115.1 - 1.2e-57 195.5 0.3 7.5e-45 153.2 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EAU87115.1 - 1.7e-09 36.9 0.0 4.8e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 EAU87115.1 - 0.003 16.6 0.0 0.075 12.0 0.0 2.5 2 1 0 2 2 2 1 Type IV pilus assembly protein PilM; DUF2834 PF11196.8 EAU87116.2 - 1.8e-07 31.4 8.4 0.0012 19.1 0.6 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) DUF2214 PF09980.9 EAU87116.2 - 0.03 14.1 0.4 0.055 13.3 0.4 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2214) MerC PF03203.14 EAU87117.2 - 0.81 10.2 7.7 6.2 7.3 0.3 3.0 3 0 0 3 3 3 0 MerC mercury resistance protein DUF948 PF06103.11 EAU87120.2 - 0.014 15.6 2.5 0.032 14.5 2.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 EAU87120.2 - 0.15 12.6 4.3 0.28 11.7 4.3 1.4 1 0 0 1 1 1 0 YtxH-like protein NINJA_B PF16136.5 EAU87123.1 - 0.45 10.9 9.8 0.14 12.5 4.5 2.5 2 0 0 2 2 2 0 Putative nuclear localisation signal Rrn6 PF10214.9 EAU87123.1 - 9.2 4.6 22.7 1 7.8 11.8 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Oxysterol_BP PF01237.18 EAU87124.1 - 1.9e-132 441.6 0.0 3.1e-132 440.9 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 EAU87124.1 - 2.3e-12 47.3 0.1 7.3e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU87124.1 - 6.1e-12 45.5 0.6 2.8e-07 30.7 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 EAU87124.1 - 2.6e-11 43.9 0.0 7.2e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EAU87124.1 - 8.1e-10 39.0 0.1 5.2e-05 23.7 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EAU87124.1 - 1.4e-09 38.0 1.9 0.035 14.6 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EAU87124.1 - 1.6e-09 37.2 0.6 0.039 14.5 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat PH_8 PF15409.6 EAU87124.1 - 3e-09 37.0 1.8 9e-09 35.5 0.4 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EAU87124.1 - 1.3e-05 25.5 0.7 3.6e-05 24.1 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF5087 PF17006.5 EAU87126.2 - 0.12 12.0 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) ubiquitin PF00240.23 EAU87127.1 - 0.00019 21.1 0.2 0.012 15.4 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin family FAD_binding_3 PF01494.19 EAU87128.2 - 9.3e-20 71.2 0.0 9.7e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EAU87128.2 - 0.039 13.2 0.0 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU87128.2 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain BING4CT PF08149.11 EAU87129.1 - 8e-36 121.7 0.0 4.2e-34 116.2 0.0 2.5 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.32 EAU87129.1 - 8.2e-05 23.3 1.6 0.3 12.0 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat UPF0239 PF06783.11 EAU87130.1 - 2.8 8.2 7.8 5.8 7.2 7.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Romo1 PF10247.9 EAU87131.1 - 0.07 13.5 1.3 0.13 12.7 1.3 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF2076 PF09849.9 EAU87132.1 - 0.00072 19.7 0.4 0.00093 19.3 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF913 PF06025.12 EAU87132.1 - 0.13 11.2 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ATP11 PF06644.11 EAU87132.1 - 0.31 10.8 3.2 0.39 10.5 3.2 1.1 1 0 0 1 1 1 0 ATP11 protein MFS_1 PF07690.16 EAU87133.1 - 1.6e-36 125.9 37.3 1.6e-36 125.9 37.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU87133.1 - 3.1e-06 26.3 34.1 4.3e-05 22.6 33.7 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EAU87133.1 - 0.00047 18.7 1.7 0.00086 17.8 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CCSMST1 PF15013.6 EAU87135.1 - 0.12 12.5 0.4 23 5.3 0.1 2.5 2 0 0 2 2 2 0 CCSMST1 family Mem_trans PF03547.18 EAU87136.1 - 4.6e-19 68.1 0.0 7.8e-19 67.3 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein Aldedh PF00171.22 EAU87137.1 - 7.6e-185 614.8 1.4 8.6e-185 614.7 1.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EAU87137.1 - 0.0041 16.6 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Glyco_hydro_61 PF03443.14 EAU87138.1 - 1.2e-49 169.0 0.0 1.8e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Menin PF05053.13 EAU87138.1 - 0.51 8.6 3.4 0.68 8.2 3.4 1.1 1 0 0 1 1 1 0 Menin Pmp3 PF01679.17 EAU87139.1 - 2.3e-21 75.7 9.0 3e-21 75.3 9.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator YL1_C PF08265.11 EAU87140.2 - 3.2e-14 52.4 0.6 6.8e-14 51.3 0.6 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF3454 PF11936.8 EAU87140.2 - 1 9.8 6.5 0.2 12.1 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) CPL PF08144.11 EAU87141.1 - 9.6e-40 136.2 2.3 5.9e-35 120.7 0.0 4.9 4 2 2 6 6 6 2 CPL (NUC119) domain PUF PF00806.19 EAU87141.1 - 0.0063 16.1 1.9 1.7 8.5 0.1 3.9 4 0 0 4 4 4 1 Pumilio-family RNA binding repeat YqcI_YcgG PF08892.11 EAU87141.1 - 0.092 12.6 0.2 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 YqcI/YcgG family SRI PF08236.11 EAU87141.1 - 3.2 8.0 8.7 17 5.6 0.9 3.8 4 0 0 4 4 4 0 SRI (Set2 Rpb1 interacting) domain ubiquitin PF00240.23 EAU87142.1 - 1.4e-09 37.6 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAU87142.1 - 1.5e-06 28.0 0.0 2.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like F-box-like PF12937.7 EAU87143.1 - 3.2e-09 36.5 2.8 3.8e-09 36.3 0.9 2.2 2 0 0 2 2 2 1 F-box-like APC_N_CC PF16689.5 EAU87143.1 - 0.061 13.4 0.5 0.14 12.2 0.5 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain ESR1_C PF12743.7 EAU87143.1 - 0.14 11.9 3.2 0.074 12.8 0.5 1.9 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal F-box PF00646.33 EAU87143.1 - 0.55 10.2 2.6 1.7 8.6 0.3 2.6 2 0 0 2 2 2 0 F-box domain PNP_UDP_1 PF01048.20 EAU87144.2 - 4.5e-29 101.4 0.0 6e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_tran_WecB PF03808.13 EAU87144.2 - 0.097 12.6 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family HMG_box PF00505.19 EAU87145.2 - 3.6e-17 62.5 1.0 5.7e-17 61.9 1.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU87145.2 - 9.4e-16 58.2 0.6 1.7e-15 57.4 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EAU87145.2 - 0.0034 17.9 0.0 0.0062 17.1 0.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 adh_short_C2 PF13561.6 EAU87146.1 - 4.8e-48 163.8 1.3 6e-48 163.4 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU87146.1 - 6.6e-34 117.1 0.8 8.1e-34 116.8 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU87146.1 - 1e-09 38.6 0.2 1.5e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EAU87146.1 - 0.0061 16.0 0.3 0.0081 15.6 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3869 PF12985.7 EAU87146.1 - 0.12 12.8 1.5 3.5 8.0 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3869) Fasciclin PF02469.22 EAU87149.2 - 1.8e-26 92.9 0.0 4.3e-17 62.5 0.0 2.6 2 0 0 2 2 2 2 Fasciclin domain Selenoprotein_S PF06936.11 EAU87150.1 - 3.9 7.2 0.0 3.9 7.2 0.0 3.5 3 1 1 4 4 4 0 Selenoprotein S (SelS) NAP PF00956.18 EAU87151.2 - 9.6e-89 297.1 4.0 1.2e-88 296.8 4.0 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Drc1-Sld2 PF11719.8 EAU87151.2 - 0.059 12.9 3.7 0.078 12.5 3.7 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Cwf_Cwc_15 PF04889.12 EAU87151.2 - 6.8 6.3 16.4 0.34 10.6 10.8 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TauD PF02668.16 EAU87152.1 - 4.8e-57 193.8 0.9 5.8e-57 193.5 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Spt20 PF12090.8 EAU87153.1 - 1.3 8.6 6.8 1.6 8.2 6.8 1.1 1 0 0 1 1 1 0 Spt20 family U79_P34 PF03064.16 EAU87153.1 - 9.2 5.6 11.3 15 4.8 11.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 F-box-like PF12937.7 EAU87156.2 - 0.019 14.8 0.4 0.064 13.2 0.4 2.0 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EAU87156.2 - 0.09 12.7 0.3 0.35 10.8 0.3 2.0 1 0 0 1 1 1 0 F-box domain TauD PF02668.16 EAU87157.1 - 3.1e-63 214.1 0.5 3.8e-63 213.8 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fasciclin PF02469.22 EAU87158.1 - 1.3e-23 83.6 0.1 9.4e-14 51.7 0.0 2.6 2 1 0 2 2 2 2 Fasciclin domain SIS_2 PF13580.6 EAU87158.1 - 0.0092 16.0 0.2 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 SIS domain AXE1 PF05448.12 EAU87159.1 - 0.019 13.7 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF43 PF01861.16 EAU87159.1 - 0.096 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain F-box-like PF12937.7 EAU87160.2 - 2e-07 30.8 2.5 4.7e-07 29.6 0.8 2.6 2 1 0 2 2 2 1 F-box-like APG6_N PF17675.1 EAU87160.2 - 0.094 13.3 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Tektin PF03148.14 EAU87160.2 - 0.13 11.0 0.5 0.21 10.3 0.5 1.2 1 0 0 1 1 1 0 Tektin family Pkinase PF00069.25 EAU87161.2 - 9.1e-69 231.7 0.0 9.5e-67 225.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87161.2 - 9e-36 123.5 0.0 3.9e-32 111.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAU87161.2 - 4.1e-05 23.0 0.0 6.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAU87161.2 - 5e-05 22.3 0.1 5e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EAU87161.2 - 0.029 13.7 0.2 0.052 12.9 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EAU87161.2 - 0.11 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Zn_clus PF00172.18 EAU87165.2 - 1.4e-07 31.6 11.3 2e-07 31.0 11.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_1 PF00734.18 EAU87167.1 - 4.4e-13 48.9 14.1 4.4e-13 48.9 14.1 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain AXE1 PF05448.12 EAU87167.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CBM_1 PF00734.18 EAU87168.1 - 8.7e-11 41.6 12.0 8.7e-11 41.6 12.0 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Trypan_PARP PF05887.11 EAU87170.2 - 0.00012 22.1 24.0 0.00028 20.9 24.0 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) AXE1 PF05448.12 EAU87170.2 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) FAP PF07174.11 EAU87170.2 - 3.9 6.9 16.4 0.034 13.6 8.2 1.6 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) LysM PF01476.20 EAU87171.1 - 2.6e-13 49.8 0.0 9.1e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 LysM domain Epimerase PF01370.21 EAU87173.2 - 1.5e-12 47.5 0.1 1.7e-12 47.3 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EAU87173.2 - 5.8e-11 41.9 0.1 6.9e-11 41.7 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAU87173.2 - 3.4e-08 33.3 0.2 4e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EAU87173.2 - 2.5e-07 30.8 0.2 2.9e-07 30.6 0.2 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EAU87173.2 - 5.2e-06 26.2 0.4 5.9e-06 26.0 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EAU87173.2 - 5.4e-06 25.8 0.1 0.061 12.5 0.0 2.0 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EAU87173.2 - 0.00035 19.8 0.2 0.0023 17.1 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EAU87174.2 - 2.9e-22 79.1 17.9 4.3e-22 78.5 17.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_5 PF00266.19 EAU87175.1 - 4.9e-18 65.2 0.0 6.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EAU87175.1 - 4.1e-07 29.6 0.4 6.1e-06 25.8 0.4 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EAU87175.1 - 2.1e-05 23.9 0.0 2.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II polyprenyl_synt PF00348.17 EAU87176.2 - 5.8e-61 205.8 0.0 7.4e-57 192.3 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase DUF5429 PF17494.2 EAU87176.2 - 0.04 14.0 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5429) Chitin_synth_1 PF01644.17 EAU87177.1 - 4.6e-66 221.8 0.1 7.9e-66 221.0 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EAU87177.1 - 4.8e-29 100.1 0.1 1e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EAU87177.1 - 8.7e-25 87.3 0.1 2.7e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAU87177.1 - 7.4e-10 39.1 6.8 7.4e-10 39.1 6.8 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 zf-4CXXC_R1 PF10497.9 EAU87178.2 - 1.2e-08 35.1 15.7 2.6e-08 34.0 15.7 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 SR-25 PF10500.9 EAU87178.2 - 0.00099 18.8 11.1 0.00099 18.8 11.1 5.4 6 0 0 6 6 6 1 Nuclear RNA-splicing-associated protein HSP20 PF00011.21 EAU87179.1 - 7e-22 77.5 0.0 1e-21 76.9 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAU87179.1 - 1.9e-09 36.9 0.0 2.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FXMR_C2 PF16098.5 EAU87179.1 - 0.0045 17.4 1.1 0.037 14.5 0.1 2.1 2 0 0 2 2 2 1 Fragile X-related mental retardation protein C-terminal region 2 FKBP26_C PF18046.1 EAU87179.1 - 0.047 13.8 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 FKBP26_C-terminal TubC_N PF18563.1 EAU87179.1 - 0.061 13.3 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 TubC N-terminal docking domain CS PF04969.16 EAU87179.1 - 0.077 14.0 0.0 0.17 12.9 0.0 1.6 1 1 0 1 1 1 0 CS domain Cwf_Cwc_15 PF04889.12 EAU87180.2 - 0.057 13.2 1.1 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 EAU87180.2 - 0.26 11.2 15.1 0.11 12.5 8.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UPF0561 PF10573.9 EAU87180.2 - 0.64 10.2 6.0 0.14 12.3 1.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Acetyltransf_1 PF00583.25 EAU87181.1 - 5.6e-11 42.7 0.0 7.2e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU87181.1 - 5.4e-08 32.8 0.0 7.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU87181.1 - 6.7e-08 32.8 0.0 9.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.26 EAU87183.2 - 1.2e-08 35.0 0.0 2.2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU87183.2 - 7.8e-08 32.2 0.2 2.4e-07 30.6 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acyl_transf_1 PF00698.21 EAU87184.2 - 9.1e-44 150.2 0.0 1.4e-43 149.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EAU87184.2 - 5.3e-36 124.4 0.0 1.5e-35 122.9 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.10 EAU87184.2 - 3.6e-34 118.3 0.1 2e-31 109.3 0.0 2.4 2 0 0 2 2 2 2 KR domain NAD_binding_4 PF07993.12 EAU87184.2 - 2.3e-23 82.7 0.0 9.5e-11 41.3 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein Ketoacyl-synt_C PF02801.22 EAU87184.2 - 3.6e-21 75.4 0.0 6.8e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EAU87184.2 - 3.1e-13 50.1 0.0 7.7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EAU87184.2 - 6.3e-08 32.4 0.0 0.12 11.8 0.0 3.5 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EAU87184.2 - 3.5e-06 27.3 0.1 9.5e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EAU87184.2 - 0.00054 19.5 0.0 0.0065 15.9 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EAU87184.2 - 0.0037 16.7 0.0 1 8.7 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EAU87184.2 - 0.084 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 EAU87184.2 - 0.13 11.3 0.0 0.46 9.6 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF3290 PF11694.8 EAU87190.1 - 0.01 15.8 0.5 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ctr PF04145.15 EAU87190.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Ctr copper transporter family DUF373 PF04123.13 EAU87190.1 - 0.32 10.4 3.2 1.5 8.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Tyrosinase PF00264.20 EAU87191.2 - 1.9e-40 139.5 0.1 2.5e-40 139.1 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Peroxidase_2 PF01328.17 EAU87192.2 - 8.7e-53 179.6 0.0 1.1e-52 179.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 TPD PF14811.6 EAU87192.2 - 0.3 10.9 0.7 0.53 10.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif RabGAP-TBC PF00566.18 EAU87193.2 - 1.4e-26 93.5 0.0 2.5e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.17 EAU87193.2 - 0.0015 18.2 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Trypan_PARP PF05887.11 EAU87194.2 - 0.02 14.9 4.0 0.035 14.1 4.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ProQ_C PF17516.2 EAU87194.2 - 0.26 10.7 1.8 0.88 9.0 0.2 2.1 2 0 0 2 2 2 0 ProQ C-terminal domain Abhydrolase_9_N PF15420.6 EAU87195.1 - 0.97 9.4 8.5 0.46 10.4 5.0 1.9 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Peroxidase_2 PF01328.17 EAU87196.2 - 2.4e-40 139.1 0.0 4.1e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 TPD PF14811.6 EAU87196.2 - 0.3 11.0 0.3 0.52 10.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif DUF1996 PF09362.10 EAU87197.2 - 2.3e-63 214.4 0.0 4.4e-63 213.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1586 PF07625.11 EAU87198.1 - 0.021 14.9 0.6 0.043 13.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) AATF-Che1 PF13339.6 EAU87198.1 - 0.084 13.5 2.2 0.15 12.7 2.2 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor BphX PF06139.12 EAU87200.1 - 0.047 13.6 3.0 4.9 7.1 0.1 2.8 2 1 0 2 2 2 0 BphX-like Acyl_transf_3 PF01757.22 EAU87200.1 - 0.053 12.6 19.0 0.013 14.5 10.8 2.7 1 1 2 3 3 3 0 Acyltransferase family UPF0182 PF03699.13 EAU87200.1 - 1.5 6.8 5.1 0.28 9.3 1.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) 2TM PF13239.6 EAU87200.1 - 2.4 8.5 4.9 0.69 10.3 0.3 2.5 1 1 1 2 2 2 0 2TM domain NOA36 PF06524.12 EAU87209.2 - 0.082 12.2 10.4 0.12 11.6 10.4 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EAU87209.2 - 0.27 9.5 1.4 0.25 9.6 1.4 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EAU87209.2 - 0.3 10.5 2.6 0.3 10.5 2.6 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EAU87209.2 - 1.8 7.6 12.9 2 7.5 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 EAU87209.2 - 3.5 7.3 13.4 6.1 6.5 13.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PD-C2-AF1 PF09310.10 EAU87210.2 - 0.1 12.0 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 YdaS_antitoxin PF15943.5 EAU87213.2 - 0.0089 15.9 0.9 1.3 9.0 0.1 2.3 2 0 0 2 2 2 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeodomain PF00046.29 EAU87213.2 - 0.012 15.5 1.8 0.021 14.6 0.3 2.0 2 0 0 2 2 2 0 Homeodomain DUF4149 PF13664.6 EAU87215.2 - 0.29 11.5 3.1 0.86 10.0 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF2231 PF09990.9 EAU87216.2 - 0.54 10.7 9.2 0.37 11.2 0.7 2.9 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) G_glu_transpept PF01019.21 EAU87217.2 - 0.013 14.3 0.4 0.018 13.8 0.4 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Saf_2TM PF18303.1 EAU87218.1 - 0.0052 16.4 2.9 0.039 13.5 0.4 2.5 2 1 0 2 2 2 2 SAVED-fused 2TM effector domain Ras PF00071.22 EAU87220.2 - 1.6e-19 70.1 0.0 2.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU87220.2 - 1.4e-09 38.2 0.0 2.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU87220.2 - 0.019 14.4 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family PolyA_pol_arg_C PF12626.7 EAU87220.2 - 0.028 14.5 0.1 0.056 13.5 0.1 1.4 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus NADHdh_A3 PF14987.6 EAU87221.2 - 0.066 13.5 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 ABC2_membrane PF01061.24 EAU87223.1 - 6.5e-30 104.1 20.9 1.3e-29 103.2 20.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EAU87223.1 - 2.3e-26 92.9 0.0 3.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU87223.1 - 5.6e-06 26.4 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EAU87223.1 - 5.1e-05 22.9 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EAU87223.1 - 6.8e-05 22.4 0.0 0.083 12.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EAU87223.1 - 0.00019 21.4 0.5 0.00058 19.8 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EAU87223.1 - 0.0029 17.9 0.0 0.018 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU87223.1 - 0.0069 16.8 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EAU87223.1 - 0.022 15.3 0.0 0.037 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU87223.1 - 0.069 12.7 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EAU87223.1 - 0.084 13.1 1.2 0.19 12.0 0.1 2.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EAU87223.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain V-SNARE PF05008.15 EAU87224.1 - 2.3e-21 75.9 1.6 3.3e-21 75.5 0.3 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EAU87224.1 - 1.4e-13 50.9 2.0 4.1e-13 49.4 2.0 1.9 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EAU87224.1 - 0.046 13.6 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 Sec20 Prominin PF05478.11 EAU87224.1 - 0.086 10.8 0.1 0.33 8.8 0.0 1.7 2 0 0 2 2 2 0 Prominin HR1 PF02185.16 EAU87224.1 - 0.19 11.8 1.8 3.6 7.8 0.1 2.7 3 0 0 3 3 3 0 Hr1 repeat Nop14 PF04147.12 EAU87228.2 - 0.029 12.6 6.8 0.04 12.1 6.8 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4127 PF13552.6 EAU87228.2 - 0.062 11.9 0.2 0.11 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) FlbD PF06289.11 EAU87228.2 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Spore_GerQ PF09671.10 EAU87230.2 - 0.0064 16.5 1.0 9 6.4 0.1 3.4 1 1 3 4 4 4 3 Spore coat protein (Spore_GerQ) FadA PF09403.10 EAU87230.2 - 0.6 10.6 1.0 11 6.6 0.1 2.3 1 1 1 2 2 2 0 Adhesion protein FadA F-box-like PF12937.7 EAU87234.2 - 8.5e-05 22.4 0.2 0.00019 21.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU87235.1 - 0.0037 17.1 0.2 0.0089 15.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF1240 PF06836.12 EAU87236.2 - 0.033 14.7 1.5 0.067 13.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) 4HBT_2 PF13279.6 EAU87237.2 - 7.8e-07 29.6 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3808 PF10300.9 EAU87238.1 - 1.8e-80 271.0 0.0 2.7e-80 270.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 EAU87238.1 - 0.0032 17.5 11.0 0.015 15.4 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU87238.1 - 0.0063 17.1 1.1 0.27 11.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAU87238.1 - 0.022 14.6 0.3 1.7 8.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAU87238.1 - 0.28 11.9 0.1 0.28 11.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU87238.1 - 6.5 6.8 8.1 20 5.2 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_11 PF00457.17 EAU87239.1 - 6.3e-73 244.2 19.4 7.4e-73 244.0 19.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Barttin PF15462.6 EAU87241.1 - 0.0011 18.8 0.6 0.0014 18.5 0.6 1.3 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) CCDC14 PF15254.6 EAU87241.1 - 0.0084 14.8 1.1 0.01 14.6 1.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 OrfB_IS605 PF01385.19 EAU87243.2 - 0.062 13.5 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Probable transposase Aldo_ket_red PF00248.21 EAU87247.2 - 1.8e-38 132.4 0.0 2.5e-38 131.9 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3089 PF11288.8 EAU87248.2 - 0.03 13.9 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Fur_reg_FbpB PF13040.6 EAU87249.2 - 0.082 12.5 0.6 0.13 11.9 0.6 1.2 1 0 0 1 1 1 0 Fur-regulated basic protein B Peptidase_M43 PF05572.13 EAU87254.2 - 5.5e-19 68.6 0.0 8.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87254.2 - 7.2e-06 26.3 0.1 7.9e-05 22.9 0.1 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAU87254.2 - 0.00017 21.3 0.1 0.00053 19.7 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EAU87254.2 - 0.001 19.6 0.0 0.0022 18.5 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87254.2 - 0.0051 16.7 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 Matrixin DUF4953 PF16313.5 EAU87254.2 - 0.022 14.0 0.1 0.043 13.0 0.1 1.4 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 EAU87254.2 - 0.064 12.2 0.2 0.2 10.6 0.4 1.6 2 0 0 2 2 2 0 Peptidase M66 Reprolysin_2 PF13574.6 EAU87254.2 - 0.088 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 EAU87255.2 - 5.5e-16 58.8 0.3 1.9e-15 57.1 0.3 1.8 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87255.2 - 2.9e-06 27.6 0.0 4.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU87255.2 - 0.0003 21.3 0.0 0.00053 20.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EAU87255.2 - 0.024 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.6 EAU87255.2 - 0.073 12.7 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EAU87255.2 - 0.077 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87255.2 - 0.1 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Matrixin Gram_pos_anchor PF00746.21 EAU87256.1 - 0.06 13.3 0.5 0.06 13.3 0.5 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Peptidase_M43 PF05572.13 EAU87257.2 - 6.8e-14 52.1 0.8 1.5e-13 50.9 0.8 1.6 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87257.2 - 0.00022 21.4 0.0 0.00046 20.4 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU87257.2 - 0.00073 20.0 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87257.2 - 0.045 13.6 0.1 0.097 12.5 0.1 1.7 1 1 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.8 EAU87257.2 - 0.12 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase BTB PF00651.31 EAU87260.2 - 0.19 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-MYND PF01753.18 EAU87264.1 - 5.6e-08 32.7 8.8 1.2e-07 31.6 8.8 1.6 1 0 0 1 1 1 1 MYND finger TLD PF07534.16 EAU87265.2 - 7.9e-26 90.9 0.1 5.2e-25 88.3 0.1 2.1 1 1 0 1 1 1 1 TLD Oxidored_FMN PF00724.20 EAU87267.1 - 1.1e-94 317.5 0.0 1.3e-94 317.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EAU87267.1 - 0.074 12.5 0.1 0.19 11.1 0.0 1.7 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel OPT PF03169.15 EAU87268.2 - 1.5e-148 496.2 41.9 1.7e-148 496.0 41.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Tyrosinase PF00264.20 EAU87270.2 - 2.4e-32 113.0 0.0 4.3e-31 108.9 0.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase AIRS PF00586.24 EAU87270.2 - 0.12 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain F-box-like PF12937.7 EAU87273.1 - 2.2e-06 27.4 1.1 2.2e-06 27.4 1.1 3.1 4 0 0 4 4 4 1 F-box-like HMG_box PF00505.19 EAU87276.1 - 1.8e-10 41.1 4.9 1.8e-10 41.1 4.9 2.3 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU87276.1 - 0.0028 18.2 3.6 0.0082 16.7 3.6 1.8 1 0 0 1 1 1 1 HMG-box domain NYD-SP12_N PF15015.6 EAU87277.2 - 0.071 11.5 0.0 0.098 11.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Metallophos PF00149.28 EAU87279.2 - 1.7e-31 110.4 0.1 2.8e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EAU87279.2 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PSII_BNR PF14870.6 EAU87280.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.4 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 GPP34 PF05719.11 EAU87282.2 - 1.7e-64 217.6 0.0 2.1e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Herpes_capsid PF06112.11 EAU87282.2 - 0.86 9.6 11.1 0.65 10.1 0.6 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Tim54 PF11711.8 EAU87283.2 - 0.002 17.0 9.8 0.002 17.0 9.8 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Eapp_C PF10238.9 EAU87283.2 - 0.011 15.9 11.9 0.012 15.7 11.9 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DDHD PF02862.17 EAU87283.2 - 0.011 15.9 10.0 0.011 15.9 10.0 1.1 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 EAU87283.2 - 0.02 14.4 14.6 0.021 14.3 14.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 EAU87283.2 - 0.02 15.3 13.1 0.022 15.1 13.1 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like TERB2 PF15101.6 EAU87283.2 - 0.025 14.6 22.0 0.028 14.5 22.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CobT PF06213.12 EAU87283.2 - 0.026 13.9 21.4 0.029 13.8 21.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT EFTUD2 PF16004.5 EAU87283.2 - 0.073 13.7 15.3 0.09 13.4 15.3 1.1 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Asparaginase_2 PF01112.18 EAU87283.2 - 0.082 11.9 5.0 0.085 11.9 5.0 1.2 1 0 0 1 1 1 0 Asparaginase TFIIA PF03153.13 EAU87283.2 - 0.085 12.8 44.3 0.099 12.6 44.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XRN_M PF17846.1 EAU87283.2 - 0.094 11.6 8.7 0.098 11.6 8.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF4776 PF16003.5 EAU87283.2 - 0.12 11.3 12.0 0.13 11.2 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Atg14 PF10186.9 EAU87283.2 - 0.14 11.2 15.4 0.16 11.0 15.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3408 PF11888.8 EAU87283.2 - 0.18 11.9 15.1 0.23 11.6 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CPSF100_C PF13299.6 EAU87283.2 - 0.19 11.9 13.4 0.21 11.7 13.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S64 PF08192.11 EAU87283.2 - 0.23 9.9 10.8 0.24 9.8 10.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 EAU87283.2 - 0.25 9.6 11.3 0.26 9.5 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein PRC2_HTH_1 PF18118.1 EAU87283.2 - 0.27 12.1 8.8 0.35 11.7 8.8 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Presenilin PF01080.17 EAU87283.2 - 0.29 9.8 20.3 0.32 9.7 20.3 1.0 1 0 0 1 1 1 0 Presenilin Rxt3 PF08642.10 EAU87283.2 - 0.33 11.7 7.0 0.45 11.3 7.0 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 RR_TM4-6 PF06459.12 EAU87283.2 - 0.34 10.7 15.3 0.36 10.6 15.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 EAU87283.2 - 0.35 10.6 13.5 0.37 10.5 13.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 EAU87283.2 - 0.37 9.7 14.6 0.39 9.7 14.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 FAM176 PF14851.6 EAU87283.2 - 0.39 10.4 8.6 0.46 10.1 8.6 1.1 1 0 0 1 1 1 0 FAM176 family MecA PF05389.12 EAU87283.2 - 0.4 10.3 9.8 0.49 10.0 9.8 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF3438 PF11920.8 EAU87283.2 - 0.4 9.9 12.0 0.52 9.5 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) TFB6 PF17110.5 EAU87283.2 - 0.45 10.2 8.5 0.59 9.9 8.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RP-C_C PF11800.8 EAU87283.2 - 0.52 10.4 14.9 0.63 10.1 14.9 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region BORG_CEP PF14957.6 EAU87283.2 - 0.53 11.5 8.3 0.68 11.1 8.3 1.2 1 0 0 1 1 1 0 Cdc42 effector FAM91_C PF14648.6 EAU87283.2 - 0.53 9.1 7.5 0.6 8.9 7.5 1.2 1 0 0 1 1 1 0 FAM91 C-terminus ABC2_membrane_2 PF12679.7 EAU87283.2 - 0.62 9.3 4.6 0.56 9.4 4.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein YABBY PF04690.13 EAU87283.2 - 0.64 10.6 13.5 0.79 10.3 13.5 1.1 1 0 0 1 1 1 0 YABBY protein AUX_IAA PF02309.16 EAU87283.2 - 0.68 9.7 10.1 0.75 9.6 10.1 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4770 PF15994.5 EAU87283.2 - 0.75 10.0 17.1 0.94 9.7 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF1764 PF08576.10 EAU87283.2 - 0.76 10.7 13.7 1.1 10.2 13.7 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) PAT1 PF09770.9 EAU87283.2 - 0.81 7.9 31.2 0.88 7.8 31.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 EAU87283.2 - 0.88 8.5 24.6 0.99 8.3 24.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.8 EAU87283.2 - 0.9 7.5 14.5 1 7.4 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NPR3 PF03666.13 EAU87283.2 - 0.91 8.2 13.6 0.93 8.2 13.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 F-protein PF00469.20 EAU87283.2 - 0.95 9.0 12.6 1.1 8.8 12.6 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef CCDC53 PF10152.9 EAU87283.2 - 1.1 9.7 18.9 1.3 9.4 18.9 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM60A PF15396.6 EAU87283.2 - 1.1 9.2 10.9 1.2 9.1 10.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Sec62 PF03839.16 EAU87283.2 - 1.1 8.7 10.4 1.3 8.5 10.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Baculo_PP31 PF05311.11 EAU87283.2 - 1.1 8.7 14.2 1.4 8.4 14.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) ALMT PF11744.8 EAU87283.2 - 1.1 8.0 12.2 1.2 7.9 12.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SART-1 PF03343.13 EAU87283.2 - 1.1 7.7 18.3 1.2 7.6 18.3 1.0 1 0 0 1 1 1 0 SART-1 family CLN3 PF02487.17 EAU87283.2 - 1.2 8.1 11.6 1.3 8.0 11.6 1.0 1 0 0 1 1 1 0 CLN3 protein Ctr PF04145.15 EAU87283.2 - 1.2 9.7 8.6 1.4 9.6 8.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family CTU2 PF10288.9 EAU87283.2 - 1.3 9.3 12.9 1.7 8.9 12.9 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 RED_N PF07808.13 EAU87283.2 - 1.4 8.4 16.7 2 7.9 16.7 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region Neur_chan_memb PF02932.16 EAU87283.2 - 1.4 8.9 12.8 1.5 8.8 12.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDM10 PF12519.8 EAU87283.2 - 1.6 7.5 13.0 1.7 7.4 13.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 HGTP_anticodon2 PF12745.7 EAU87283.2 - 1.6 8.1 14.4 1.9 8.0 14.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Gti1_Pac2 PF09729.9 EAU87283.2 - 1.6 8.8 13.7 1.9 8.5 13.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Membralin PF09746.9 EAU87283.2 - 1.6 7.6 8.5 1.7 7.6 8.5 1.0 1 0 0 1 1 1 0 Tumour-associated protein MCM_bind PF09739.9 EAU87283.2 - 1.7 7.0 14.4 1.9 6.8 14.4 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Connexin PF00029.19 EAU87283.2 - 1.7 8.3 14.0 2 8.1 14.0 1.1 1 0 0 1 1 1 0 Connexin DUF4746 PF15928.5 EAU87283.2 - 1.7 8.0 11.9 2 7.7 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NARP1 PF12569.8 EAU87283.2 - 1.7 7.4 15.3 2 7.2 15.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UPF0560 PF10577.9 EAU87283.2 - 1.8 7.0 28.3 2 6.8 28.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MMR1 PF08505.10 EAU87283.2 - 2.1 8.6 19.8 2.4 8.4 19.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Ureide_permease PF07168.11 EAU87283.2 - 2.1 7.0 7.1 2.4 6.8 7.1 1.1 1 0 0 1 1 1 0 Ureide permease PepSY_TM PF03929.16 EAU87283.2 - 2.1 8.0 10.5 2.3 7.8 10.5 1.2 1 0 0 1 1 1 0 PepSY-associated TM region BRF1 PF07741.13 EAU87283.2 - 2.3 8.6 14.0 3.5 8.0 14.0 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF913 PF06025.12 EAU87283.2 - 2.4 7.0 11.3 2.7 6.9 11.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peroxin-13_N PF04088.13 EAU87283.2 - 2.5 8.4 10.1 3.4 7.9 10.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Folliculin PF11704.8 EAU87283.2 - 2.6 7.9 11.8 2.9 7.8 11.8 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PIP5K PF01504.18 EAU87283.2 - 2.7 7.2 15.2 3.4 6.8 15.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Plasmodium_Vir PF05795.11 EAU87283.2 - 3 7.2 10.6 3.2 7.1 10.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pal1 PF08316.11 EAU87283.2 - 3.3 8.5 9.5 4.9 7.9 9.5 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Lin-8 PF03353.15 EAU87283.2 - 3.4 7.2 24.3 4 6.9 24.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF966 PF06136.13 EAU87283.2 - 3.4 7.3 13.9 4 7.1 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Paf1 PF03985.13 EAU87283.2 - 3.4 6.6 21.1 4.1 6.3 21.1 1.0 1 0 0 1 1 1 0 Paf1 DUF1387 PF07139.11 EAU87283.2 - 3.6 7.2 18.3 4.2 7.0 18.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sin_N PF04801.13 EAU87283.2 - 3.7 6.7 24.6 3.6 6.7 24.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region FHIPEP PF00771.20 EAU87283.2 - 4.1 5.7 10.0 4.5 5.6 10.0 1.1 1 0 0 1 1 1 0 FHIPEP family G0-G1_switch_2 PF15103.6 EAU87283.2 - 4.9 7.6 12.2 7.2 7.1 12.2 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Paramyxo_ncap PF00973.19 EAU87283.2 - 5 5.9 10.4 5.3 5.8 10.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PPL5 PF18168.1 EAU87283.2 - 5.2 6.3 12.5 6.6 5.9 12.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 SprA-related PF12118.8 EAU87283.2 - 5.4 6.0 32.0 6 5.9 32.0 1.2 1 0 0 1 1 1 0 SprA-related family Pannexin_like PF12534.8 EAU87283.2 - 5.5 6.0 12.1 6.5 5.7 12.1 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 SID-1_RNA_chan PF13965.6 EAU87283.2 - 5.6 5.2 8.3 6.3 5.1 8.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4638 PF15472.6 EAU87283.2 - 5.6 6.6 14.4 6.3 6.4 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) GREB1 PF15782.5 EAU87283.2 - 6.1 3.8 19.3 7.1 3.6 19.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2072 PF09845.9 EAU87283.2 - 6.3 7.1 11.6 8.1 6.7 11.6 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein Otopetrin PF03189.13 EAU87283.2 - 7.3 5.3 10.0 8.3 5.1 10.0 1.1 1 0 0 1 1 1 0 Otopetrin Peptidase_S49_N PF08496.10 EAU87283.2 - 7.6 6.6 14.6 10 6.1 14.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EMC3_TMCO1 PF01956.16 EAU87283.2 - 7.6 6.2 14.5 8.2 6.1 14.5 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CSG2 PF16965.5 EAU87283.2 - 7.7 5.3 10.2 8.7 5.2 10.2 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator EOS1 PF12326.8 EAU87283.2 - 7.8 6.4 10.7 9.9 6.0 10.7 1.1 1 0 0 1 1 1 0 N-glycosylation protein AIF_C PF14721.6 EAU87283.2 - 8.1 6.8 15.7 12 6.3 15.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3381 PF11861.8 EAU87283.2 - 8.2 6.2 19.6 11 5.8 19.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) V_ATPase_I PF01496.19 EAU87283.2 - 9.3 4.0 19.7 11 3.8 19.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.10 EAU87283.2 - 9.9 6.0 15.9 13 5.6 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Dicty_REP PF05086.12 EAU87283.2 - 9.9 4.0 9.6 9.1 4.1 9.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein p450 PF00067.22 EAU87285.2 - 4.5e-64 216.9 0.0 5.8e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Spc29 PF17082.5 EAU87294.2 - 0.012 15.5 0.2 0.012 15.4 0.2 1.1 1 0 0 1 1 1 0 Spindle Pole Component 29 HTH_19 PF12844.7 EAU87294.2 - 0.024 14.7 0.9 0.043 13.8 0.9 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DHR10 PF18595.1 EAU87294.2 - 0.025 14.6 0.3 0.051 13.6 0.3 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain SlyX PF04102.12 EAU87294.2 - 0.14 12.8 0.2 0.4 11.3 0.2 1.8 1 1 0 1 1 1 0 SlyX DNA_topoisoIV PF00521.20 EAU87295.2 - 4.1e-49 167.6 6.4 5.3e-28 98.1 0.7 3.1 2 1 1 3 3 3 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EAU87295.2 - 1.5e-36 125.5 4.4 3.1e-36 124.5 4.4 1.6 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM HATPase_c PF02518.26 EAU87295.2 - 1.2e-12 48.3 0.0 2.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EAU87295.2 - 7.2e-09 35.8 0.0 2e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Toprim domain PspA_IM30 PF04012.12 EAU87295.2 - 0.00022 20.9 1.1 0.00043 19.9 1.1 1.4 1 0 0 1 1 1 1 PspA/IM30 family Phage_GP20 PF06810.11 EAU87295.2 - 0.00058 19.7 0.6 0.0024 17.7 0.6 2.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 APG6_N PF17675.1 EAU87295.2 - 0.0018 18.8 2.2 0.0049 17.4 2.2 1.7 1 0 0 1 1 1 1 Apg6 coiled-coil region Cauli_AT PF03233.13 EAU87295.2 - 0.0056 16.6 0.0 0.02 14.8 0.0 1.9 1 0 0 1 1 1 1 Aphid transmission protein TSC22 PF01166.18 EAU87295.2 - 0.01 16.1 2.3 0.01 16.1 2.3 2.4 2 1 0 2 2 2 0 TSC-22/dip/bun family HrpB7 PF09486.10 EAU87295.2 - 0.01 16.2 0.6 0.02 15.3 0.6 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 EAU87295.2 - 0.011 15.8 4.0 0.024 14.7 4.0 1.6 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DNA_gyraseB PF00204.25 EAU87295.2 - 0.019 14.5 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 DNA gyrase B HAUS-augmin3 PF14932.6 EAU87295.2 - 0.019 14.6 1.5 0.04 13.5 1.5 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.9 EAU87295.2 - 0.047 14.0 2.8 0.071 13.4 0.7 2.4 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.6 EAU87295.2 - 0.089 12.2 0.9 0.18 11.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Csm1_N PF18504.1 EAU87295.2 - 0.12 12.8 3.0 0.44 10.9 3.0 2.0 1 0 0 1 1 1 0 Csm1 N-terminal domain SlyX PF04102.12 EAU87295.2 - 0.13 12.9 1.6 0.4 11.3 1.6 1.8 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 EAU87295.2 - 0.75 9.6 2.9 2.9 7.7 2.9 2.1 1 0 0 1 1 1 0 Septum formation initiator Tet_JBP PF12851.7 EAU87306.1 - 6.7e-09 35.5 0.0 1.6e-08 34.3 0.0 1.5 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy PF03171.20 EAU87306.1 - 0.00082 19.8 0.0 0.027 15.0 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily KDZ PF18758.1 EAU87312.2 - 5.7e-41 140.6 0.1 1e-40 139.7 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU87312.2 - 2.4e-24 85.6 0.2 6e-21 74.6 0.1 2.6 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases DUF3673 PF12425.8 EAU87313.1 - 3.4 7.7 5.3 27 4.7 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3673) COG2 PF06148.11 EAU87314.1 - 0.00045 20.3 2.7 0.00045 20.3 2.7 2.7 2 1 1 3 3 2 1 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 EAU87314.1 - 0.00053 20.0 2.1 0.00053 20.0 2.1 3.4 3 0 0 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 EAU87314.1 - 0.00058 19.9 0.7 0.64 10.1 0.1 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.12 EAU87314.1 - 0.00084 17.6 6.8 0.012 13.9 2.6 2.2 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA DUF4795 PF16043.5 EAU87314.1 - 0.0018 17.9 7.0 0.0051 16.4 6.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Laminin_II PF06009.12 EAU87314.1 - 0.002 18.2 4.5 0.0044 17.0 2.9 2.3 1 1 1 2 2 2 1 Laminin Domain II Filament PF00038.21 EAU87314.1 - 0.0034 17.0 5.1 0.0034 17.0 5.1 2.6 1 1 1 2 2 2 1 Intermediate filament protein Macoilin PF09726.9 EAU87314.1 - 0.0064 15.1 10.0 0.013 14.1 10.0 1.4 1 0 0 1 1 1 1 Macoilin family Rootletin PF15035.6 EAU87314.1 - 0.007 16.4 7.6 0.0091 16.0 2.1 2.6 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.11 EAU87314.1 - 0.008 16.4 3.8 0.008 16.4 3.8 3.0 3 2 0 3 3 2 1 Autophagy protein 16 (ATG16) RasGAP_C PF03836.15 EAU87314.1 - 0.014 15.5 1.4 0.044 13.9 1.4 1.8 1 0 0 1 1 1 0 RasGAP C-terminus Exonuc_VII_L PF02601.15 EAU87314.1 - 0.015 14.9 1.7 0.029 14.0 1.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF713 PF05218.14 EAU87314.1 - 0.017 14.8 0.8 0.033 13.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF713) TBCC_N PF16752.5 EAU87314.1 - 0.023 15.1 0.7 0.023 15.1 0.7 2.9 4 0 0 4 4 2 0 Tubulin-specific chaperone C N-terminal domain FAM104 PF15434.6 EAU87314.1 - 0.029 14.9 1.4 0.085 13.4 1.4 1.7 1 0 0 1 1 1 0 Family 104 MscS_porin PF12795.7 EAU87314.1 - 0.034 13.7 3.8 2.5 7.6 4.4 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FUSC PF04632.12 EAU87314.1 - 0.046 12.3 0.4 0.069 11.7 0.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 EAU87314.1 - 0.049 12.9 3.3 0.083 12.1 2.6 1.7 1 1 0 1 1 1 0 TMPIT-like protein Nup88 PF10168.9 EAU87314.1 - 0.11 10.3 2.8 0.17 9.7 2.8 1.2 1 0 0 1 1 1 0 Nuclear pore component Atg14 PF10186.9 EAU87314.1 - 0.11 11.5 2.7 0.24 10.5 2.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 EAU87314.1 - 0.12 10.3 1.9 0.19 9.6 1.9 1.3 1 0 0 1 1 1 0 Prominin BBP1_C PF15272.6 EAU87314.1 - 0.13 12.1 10.4 0.45 10.3 4.7 2.6 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF3584 PF12128.8 EAU87314.1 - 0.14 9.6 15.8 0.017 12.6 10.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 EAU87314.1 - 0.24 11.6 5.8 0.45 10.7 4.1 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MPS2 PF17060.5 EAU87314.1 - 0.27 10.5 5.7 0.49 9.6 5.7 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 NPV_P10 PF05531.12 EAU87314.1 - 0.32 11.5 9.0 1 9.9 3.0 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Cluap1 PF10234.9 EAU87314.1 - 0.36 10.2 5.6 0.094 12.1 1.4 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF948 PF06103.11 EAU87314.1 - 0.48 10.7 5.3 0.67 10.3 1.2 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.10 EAU87314.1 - 0.94 9.8 8.2 0.4 11.0 3.7 2.7 2 1 0 3 3 3 0 Tup N-terminal DUF1664 PF07889.12 EAU87314.1 - 1.4 8.9 6.0 2 8.5 3.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EAU87314.1 - 1.5 9.2 6.1 5.1 7.5 0.0 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TolA_bind_tri PF16331.5 EAU87314.1 - 3 8.0 12.1 9.4 6.4 3.2 3.8 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF4763 PF15960.5 EAU87314.1 - 3.6 6.8 9.2 0.14 11.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Synaptobrevin PF00957.21 EAU87314.1 - 3.6 7.4 6.4 28 4.6 3.2 2.7 1 1 1 2 2 2 0 Synaptobrevin CALCOCO1 PF07888.11 EAU87320.2 - 0.005 15.8 3.7 0.0074 15.2 3.7 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like MTBP_C PF14920.6 EAU87320.2 - 0.039 13.7 0.4 0.039 13.7 0.4 1.7 2 0 0 2 2 2 0 MDM2-binding Fzo_mitofusin PF04799.13 EAU87320.2 - 0.05 13.1 0.5 0.075 12.6 0.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region YicC_N PF03755.13 EAU87320.2 - 0.054 13.9 0.3 0.091 13.2 0.3 1.3 1 0 0 1 1 1 0 YicC-like family, N-terminal region Fibin PF15819.5 EAU87320.2 - 0.075 12.8 0.3 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 Fin bud initiation factor homologue Cnn_1N PF07989.11 EAU87320.2 - 0.25 11.5 2.1 0.69 10.1 2.1 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ACR_tran PF00873.19 EAU87320.2 - 0.3 8.7 0.0 0.38 8.3 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Spc7 PF08317.11 EAU87320.2 - 0.46 9.3 3.9 0.72 8.7 3.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-MYND PF01753.18 EAU87325.2 - 1.3e-09 37.9 12.8 2.6e-09 37.0 12.8 1.5 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 EAU87325.2 - 8.3e-06 25.5 0.1 1.1 9.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU87325.2 - 3.7e-05 23.9 0.5 0.28 11.5 0.1 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU87325.2 - 0.00028 21.5 0.4 0.26 12.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU87325.2 - 0.025 14.4 0.1 4.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU87325.2 - 0.031 15.1 2.1 11 7.1 0.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU87325.2 - 0.042 13.7 0.5 42 4.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAU87325.2 - 0.1 12.7 0.4 29 4.8 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 EAU87325.2 - 0.13 12.5 0.0 5.4 7.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S19 PF00203.21 EAU87326.1 - 1.3e-26 92.3 0.1 1.7e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3592 PF12158.8 EAU87327.2 - 0.37 10.8 3.9 0.97 9.5 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Pkinase PF00069.25 EAU87328.1 - 1.2e-73 247.7 0.4 1.2e-73 247.7 0.4 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87328.1 - 1.8e-51 175.0 0.3 1.8e-51 175.0 0.3 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EAU87328.1 - 8.5e-23 80.5 0.3 3.2e-22 78.6 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EAU87328.1 - 4.5e-07 29.5 0.0 8.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAU87328.1 - 6.1e-07 28.6 1.6 5.7e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase PH PF00169.29 EAU87328.1 - 7e-07 29.7 0.4 1.5e-06 28.6 0.4 1.5 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 EAU87328.1 - 5.6e-06 25.5 0.2 1e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAU87328.1 - 0.0014 18.6 5.7 0.0043 17.0 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAU87328.1 - 0.034 13.2 0.1 0.065 12.3 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 CDC45 PF02724.14 EAU87328.1 - 0.1 10.9 3.7 0.13 10.5 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TERB2 PF15101.6 EAU87328.1 - 0.13 12.2 2.4 0.25 11.4 2.4 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 U1snRNP70_N PF12220.8 EAU87328.1 - 1.9 9.2 14.7 12 6.7 9.0 2.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RR_TM4-6 PF06459.12 EAU87328.1 - 4.2 7.1 8.7 8.5 6.1 8.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EAU87328.1 - 7.1 5.3 8.4 11 4.6 8.4 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 EAU87329.2 - 0.033 13.0 0.2 0.028 13.3 0.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 EAU87329.2 - 0.099 11.8 9.5 0.13 11.5 9.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CCDC24 PF15669.5 EAU87329.2 - 0.29 11.0 2.2 0.49 10.2 2.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SPX PF03105.19 EAU87329.2 - 0.85 9.5 7.7 1.1 9.1 7.7 1.1 1 0 0 1 1 1 0 SPX domain IBR PF01485.21 EAU87331.2 - 3.8e-15 55.9 30.8 1.1e-08 35.1 2.5 3.7 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Pkinase_fungal PF17667.1 EAU87334.1 - 1.1e-08 34.3 0.1 1.4e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase ApoO PF09769.9 EAU87335.1 - 5.1e-27 94.4 0.4 1.4e-26 92.9 0.0 1.8 2 1 0 2 2 2 1 Apolipoprotein O YtxH PF12732.7 EAU87335.1 - 0.097 13.2 1.1 0.28 11.8 0.7 2.0 2 0 0 2 2 2 0 YtxH-like protein DUF438 PF04282.13 EAU87335.1 - 0.13 12.2 0.7 0.27 11.2 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF438) Apolipoprotein PF01442.18 EAU87336.2 - 0.013 15.4 0.8 0.024 14.5 0.1 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain OTT_1508_deam PF14441.6 EAU87337.2 - 3.1e-13 49.5 0.0 8.8e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase Pkinase_fungal PF17667.1 EAU87338.1 - 8.5e-13 47.8 0.0 1.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU87338.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87338.1 - 0.21 10.8 0.0 0.31 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU87339.2 - 5.2e-12 45.2 0.0 6.5e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 EAU87340.2 - 2e-09 36.8 0.0 2.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase UnbV_ASPIC PF07593.12 EAU87340.2 - 0.17 11.9 0.1 0.39 10.7 0.1 1.6 1 0 0 1 1 1 0 ASPIC and UnbV Pkinase_fungal PF17667.1 EAU87341.2 - 1.9e-35 122.5 0.0 2.6e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 EAU87342.2 - 2e-23 82.9 0.0 7.4e-22 77.7 0.0 2.6 1 1 0 1 1 1 1 Fungal protein kinase Metallophos PF00149.28 EAU87343.2 - 1e-31 111.1 0.0 1.4e-31 110.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EAU87343.2 - 0.009 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 EAU87343.2 - 0.023 15.1 0.5 0.046 14.2 0.5 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain TAD2 PF18521.1 EAU87343.2 - 0.074 13.0 0.4 0.23 11.5 0.4 1.8 1 0 0 1 1 1 0 Transactivation domain 2 Peroxidase_ext PF11895.8 EAU87345.1 - 5e-27 93.6 0.2 9e-27 92.8 0.2 1.4 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 EAU87345.1 - 2.2e-24 86.4 0.0 3.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4588 PF15251.6 EAU87346.1 - 3.7e-06 26.9 0.0 8.5e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) LCE PF14672.6 EAU87346.1 - 0.047 14.3 1.1 0.047 14.3 1.1 1.9 2 0 0 2 2 2 0 Late cornified envelope CCDC53 PF10152.9 EAU87346.1 - 2 8.8 6.7 0.36 11.2 2.6 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex F-box-like PF12937.7 EAU87351.2 - 1.1e-06 28.4 0.3 1.8e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU87352.2 - 9.1e-06 25.5 2.4 0.00014 21.7 0.2 3.5 3 1 0 3 3 3 1 F-box-like F-box-like PF12937.7 EAU87353.2 - 1.9e-05 24.5 0.1 0.00071 19.4 0.0 3.1 3 1 0 3 3 3 1 F-box-like RCDG1 PF15725.5 EAU87353.2 - 0.066 13.6 0.3 0.16 12.4 0.3 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein SnoaL_2 PF12680.7 EAU87354.2 - 0.00036 21.1 0.0 0.00047 20.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF563 PF04577.14 EAU87355.2 - 6.5e-17 62.4 0.0 1.1e-15 58.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Vac7 PF12751.7 EAU87356.1 - 0.26 10.7 0.8 0.37 10.2 0.8 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 F-box-like PF12937.7 EAU87357.2 - 0.00039 20.3 3.1 0.00039 20.3 3.1 2.9 3 1 0 3 3 3 1 F-box-like LRR_6 PF13516.6 EAU87357.2 - 0.013 15.5 0.2 3.4 8.0 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat zf-MYND PF01753.18 EAU87358.1 - 7.1e-06 26.0 8.9 1.5e-05 25.0 8.9 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EAU87358.1 - 0.11 12.6 2.2 0.32 11.1 2.2 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ADH_zinc_N PF00107.26 EAU87359.1 - 3.1e-17 62.8 0.0 6e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU87359.1 - 3.6e-11 42.9 0.0 6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EAU87359.1 - 0.00097 20.2 0.0 0.0018 19.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box-like PF12937.7 EAU87360.2 - 1.1e-10 41.2 5.0 0.00012 21.9 0.6 4.0 3 0 0 3 3 3 2 F-box-like Ras PF00071.22 EAU87363.2 - 1e-39 135.7 0.3 2.5e-38 131.3 0.3 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAU87363.2 - 9.4e-24 83.9 0.0 5.2e-23 81.5 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU87363.2 - 1.8e-05 24.3 0.0 0.0011 18.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAU87363.2 - 5.1e-05 23.3 0.0 9.2e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAU87363.2 - 7.3e-05 22.4 0.0 0.00023 20.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAU87363.2 - 0.00071 19.5 0.2 0.002 18.1 0.2 1.8 1 1 1 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EAU87363.2 - 0.0012 19.2 0.3 0.0095 16.3 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 EAU87363.2 - 0.0046 16.7 0.5 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EAU87363.2 - 0.0058 16.6 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Septin PF00735.18 EAU87363.2 - 0.0074 15.6 0.3 0.012 14.9 0.1 1.5 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 EAU87363.2 - 0.0082 16.4 0.1 0.017 15.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EAU87363.2 - 0.018 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU87363.2 - 0.024 14.1 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EAU87363.2 - 0.036 13.5 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 EAU87363.2 - 0.04 13.8 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EAU87363.2 - 0.061 12.9 0.1 0.091 12.3 0.1 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EAU87363.2 - 0.07 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EAU87363.2 - 0.075 13.5 0.1 0.1 13.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter Proho_convert PF12177.8 EAU87363.2 - 0.079 13.0 0.4 0.44 10.6 0.2 2.2 3 0 0 3 3 2 0 Prohormone convertase enzyme RNA_helicase PF00910.22 EAU87363.2 - 0.12 12.8 0.0 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 EAU87363.2 - 0.17 11.9 0.1 0.42 10.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU87363.2 - 0.17 12.4 0.0 0.66 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAU87363.2 - 0.17 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain F-box-like PF12937.7 EAU87364.1 - 0.026 14.4 0.0 0.083 12.8 0.0 1.8 2 0 0 2 2 2 0 F-box-like Phage_holin_8 PF16931.5 EAU87365.2 - 0.45 10.5 4.5 2.9 7.9 3.0 2.4 2 1 0 2 2 2 0 Putative phage holin Neurensin PF14927.6 EAU87365.2 - 7.8 6.2 8.2 11 5.7 1.3 2.8 1 1 2 3 3 3 0 Neurensin SLATT_5 PF18160.1 EAU87367.1 - 0.0079 15.5 3.8 0.91 8.8 0.6 2.5 2 0 0 2 2 2 2 SMODS and SLOG-associating 2TM effector domain family 5 DHHC PF01529.20 EAU87367.1 - 0.013 15.6 3.3 0.12 12.5 0.8 3.0 2 1 1 3 3 3 0 DHHC palmitoyltransferase Zn_peptidase_2 PF04298.12 EAU87367.1 - 0.054 12.9 0.2 0.16 11.4 0.2 1.8 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Ndc1_Nup PF09531.10 EAU87368.2 - 0.014 14.1 1.3 0.022 13.5 0.9 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup STE3 PF02076.15 EAU87370.1 - 4e-113 377.4 22.7 4.8e-113 377.2 22.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor TadE PF07811.12 EAU87370.1 - 0.058 13.7 0.3 0.18 12.1 0.3 1.9 1 0 0 1 1 1 0 TadE-like protein bPH_4 PF06713.11 EAU87370.1 - 0.18 11.9 0.1 0.37 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial PH domain Pheromone PF08015.11 EAU87371.1 - 0.00027 21.9 0.5 0.00037 21.5 0.5 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EAU87373.1 - 2.6e-09 38.0 1.5 5.6e-09 36.9 1.5 1.6 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EAU87374.1 - 2.7e-09 38.0 0.4 2.4e-08 34.9 0.4 1.9 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EAU87375.2 - 1.1e-09 39.2 0.4 1.4e-09 38.9 0.4 1.1 1 0 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EAU87376.1 - 2.4e-11 44.5 0.3 2.7e-11 44.3 0.3 1.0 1 0 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.15 EAU87378.2 - 9.2e-115 382.8 18.2 1.1e-114 382.5 18.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor Multi_Drug_Res PF00893.19 EAU87378.2 - 0.081 13.6 2.0 0.33 11.6 1.1 2.4 2 2 0 2 2 2 0 Small Multidrug Resistance protein MFS_1 PF07690.16 EAU87380.2 - 1.1e-35 123.2 63.2 2.5e-34 118.7 25.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EAU87380.2 - 6e-20 71.2 19.0 9.4e-20 70.6 19.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAU87380.2 - 1.4e-11 43.9 12.3 1.4e-11 43.9 12.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EAU87380.2 - 0.56 8.4 6.7 0.16 10.2 1.0 2.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_3 PF07859.13 EAU87381.2 - 2.7e-18 66.6 0.0 3.8e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU87381.2 - 2.9e-17 62.6 0.0 3.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EAU87382.1 - 5.3e-14 52.6 0.0 7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU87382.1 - 1.1e-10 41.0 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EAU87382.1 - 0.0026 18.4 0.1 0.0041 17.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.16 EAU87383.2 - 1.2e-21 77.1 48.1 4.5e-21 75.2 15.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU87383.2 - 5.9e-09 35.3 5.7 5.9e-09 35.3 5.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EAU87383.2 - 0.021 13.3 16.8 3.8 5.8 17.8 3.2 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF962 PF06127.11 EAU87383.2 - 0.044 13.9 3.6 0.68 10.1 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF962) PCI PF01399.27 EAU87386.1 - 1.7e-09 38.1 0.0 5.3e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 PCI domain DUF2156 PF09924.9 EAU87386.1 - 0.11 11.5 0.2 0.41 9.6 0.1 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2156) Say1_Mug180 PF10340.9 EAU87388.2 - 2e-17 63.1 0.0 2.9e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EAU87388.2 - 6e-14 52.4 0.0 9.4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.16 EAU87389.2 - 3.9e-18 65.5 38.1 4.6e-09 35.7 6.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU87389.2 - 7.5e-12 44.8 15.9 6.9e-11 41.7 15.9 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF5360 PF17314.2 EAU87389.2 - 0.055 13.5 0.4 0.18 11.8 0.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5360) Pkinase_fungal PF17667.1 EAU87390.2 - 1e-36 126.7 0.0 6.4e-35 120.7 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU87390.2 - 1.3e-06 28.0 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87390.2 - 0.064 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF5503 PF17607.2 EAU87390.2 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5503) RIO1 PF01163.22 EAU87390.2 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EAU87391.2 - 5.4e-27 94.6 0.0 4.9e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU87391.2 - 9.4e-05 21.9 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain STE3 PF02076.15 EAU87392.2 - 7.4e-112 373.3 17.6 8.8e-112 373.0 17.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 EAU87394.2 - 1.1e-33 116.7 15.6 7.4e-26 91.0 6.1 2.1 1 1 1 2 2 2 2 Pheromone A receptor ERM PF00769.19 EAU87396.2 - 0.54 10.0 25.0 0.78 9.5 25.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-C4H2 PF10146.9 EAU87396.2 - 1.6 9.0 14.6 2.1 8.6 14.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4706 PF15797.5 EAU87396.2 - 5.5 7.6 8.7 24 5.5 7.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4706) Calici_MSP PF05752.11 EAU87396.2 - 7.2 6.4 7.4 40 4.0 7.4 1.9 1 1 0 1 1 1 0 Calicivirus minor structural protein Nup88 PF10168.9 EAU87396.2 - 9.2 3.9 12.7 12 3.6 12.7 1.1 1 0 0 1 1 1 0 Nuclear pore component Prefoldin PF02996.17 EAU87397.1 - 1.9e-26 92.4 0.1 1.4e-25 89.5 0.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit RRM_1 PF00076.22 EAU87398.1 - 1e-78 259.1 0.1 1.2e-20 73.1 0.0 5.7 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU87398.1 - 1.1e-05 25.1 0.0 0.0032 17.3 0.0 3.6 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EAU87398.1 - 0.00044 20.2 0.0 1.3 9.1 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Smg4_UPF3 PF03467.15 EAU87398.1 - 0.00045 20.3 0.6 0.35 10.9 0.0 3.6 3 1 1 4 4 4 2 Smg-4/UPF3 family Limkain-b1 PF11608.8 EAU87398.1 - 0.00095 19.2 0.0 26 5.0 0.0 4.6 4 0 0 4 4 4 0 Limkain b1 RRM_2 PF04059.12 EAU87398.1 - 0.0027 17.9 0.0 7.7 6.8 0.0 4.1 4 0 0 4 4 4 1 RNA recognition motif 2 Spore_coat_CotO PF14153.6 EAU87398.1 - 0.22 11.5 3.7 0.51 10.2 3.7 1.6 1 0 0 1 1 1 0 Spore coat protein CotO CytochromB561_N PF09786.9 EAU87398.1 - 0.9 8.5 5.6 1.7 7.5 5.6 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Myb_DNA-binding PF00249.31 EAU87399.2 - 3.5e-14 52.7 0.0 1.1e-06 28.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU87399.2 - 1.7e-11 44.2 0.0 1.5e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain TFIIA PF03153.13 EAU87399.2 - 0.45 10.4 48.8 0.22 11.5 15.9 3.7 4 0 0 4 4 4 0 Transcription factor IIA, alpha/beta subunit DUF812 PF05667.11 EAU87403.2 - 0.00059 18.9 3.4 0.00095 18.2 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) K-box PF01486.17 EAU87403.2 - 0.0072 16.5 2.2 0.017 15.3 2.2 1.6 1 0 0 1 1 1 1 K-box region Med4 PF10018.9 EAU87403.2 - 0.0074 16.0 2.7 0.018 14.7 2.7 1.6 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1515 PF07439.11 EAU87403.2 - 0.035 14.2 1.3 0.073 13.1 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) UPF0242 PF06785.11 EAU87403.2 - 0.035 14.2 0.3 0.081 13.0 0.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LPD39 PF18858.1 EAU87403.2 - 0.078 13.1 1.6 0.14 12.2 1.6 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 FemAB PF02388.16 EAU87403.2 - 0.095 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 FemAB family Spc7 PF08317.11 EAU87403.2 - 0.13 11.1 4.4 0.27 10.1 4.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2205 PF10224.9 EAU87403.2 - 0.17 11.9 3.0 0.4 10.7 3.0 1.6 1 0 0 1 1 1 0 Short coiled-coil protein DUF4407 PF14362.6 EAU87403.2 - 0.32 10.3 2.1 0.71 9.2 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EAU87403.2 - 0.34 10.7 3.3 1.1 9.0 3.3 1.9 1 0 0 1 1 1 0 Septum formation initiator PEARLI-4 PF05278.12 EAU87403.2 - 1.5 8.4 7.3 3.1 7.3 7.3 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) TPX2 PF06886.11 EAU87403.2 - 3.5 7.9 13.8 3.9 7.8 11.7 2.1 1 1 1 2 2 2 0 Targeting protein for Xklp2 (TPX2) Atg14 PF10186.9 EAU87403.2 - 8.1 5.4 10.1 0.25 10.4 4.0 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 JSRP PF15312.6 EAU87404.1 - 0.077 12.9 0.2 18 5.4 0.0 2.9 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF2207 PF09972.9 EAU87404.1 - 1.9 7.2 4.3 1.7 7.4 0.1 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SNF2_N PF00176.23 EAU87406.2 - 6.5e-50 169.8 0.0 1.4e-49 168.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PBP1_TM PF14812.6 EAU87406.2 - 2.6 8.5 5.7 12 6.3 5.7 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1687 PF07955.11 EAU87408.2 - 5e-21 75.5 0.0 7.1e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Bac_export_2 PF01312.19 EAU87409.2 - 0.29 10.3 0.0 1.9 7.7 0.0 1.9 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family EAP30 PF04157.16 EAU87410.2 - 1.6e-38 132.3 0.0 2.1e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EAU87410.2 - 3.1e-18 65.7 0.0 5.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 EAU87410.2 - 0.00013 21.2 5.4 0.026 13.8 1.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 EAU87410.2 - 0.015 15.3 6.3 0.081 13.0 0.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 EAU87410.2 - 0.086 12.2 0.1 0.086 12.2 0.1 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PLU-1 PF08429.11 EAU87410.2 - 0.16 11.1 0.5 0.23 10.6 0.5 1.1 1 0 0 1 1 1 0 PLU-1-like protein zf-Sec23_Sec24 PF04810.15 EAU87410.2 - 0.29 11.2 5.0 3.6 7.7 0.5 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Rhodanese PF00581.20 EAU87411.1 - 1.5e-08 35.1 0.0 4.7e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Mito_carr PF00153.27 EAU87412.2 - 1.4e-56 188.4 4.2 3e-18 65.5 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein SRP9-21 PF05486.12 EAU87413.1 - 1.1e-11 45.0 3.9 6.9e-11 42.4 1.1 2.4 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.17 EAU87413.1 - 0.043 13.8 0.1 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Hydrophobin PF01185.18 EAU87414.1 - 3.8e-07 30.6 0.4 8.3e-06 26.4 0.4 2.1 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EAU87415.2 - 1e-25 90.1 5.9 1.3e-25 89.8 5.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Herpes_gE PF02480.16 EAU87416.2 - 0.058 12.1 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 EAU87416.2 - 0.14 13.0 0.0 0.24 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NCU-G1 PF15065.6 EAU87416.2 - 0.18 10.8 0.2 0.26 10.3 0.2 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 VSP PF03302.13 EAU87416.2 - 0.2 10.5 0.7 0.28 10.0 0.7 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Syndecan PF01034.20 EAU87416.2 - 2.5 8.1 3.9 4.3 7.3 3.9 1.3 1 0 0 1 1 1 0 Syndecan domain Synaptobrevin PF00957.21 EAU87418.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Synaptobrevin DUF4834 PF16118.5 EAU87421.1 - 6.2 7.9 7.7 6.6 7.8 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Gly_rich PF12810.7 EAU87421.1 - 9.4 6.1 14.1 83 3.0 14.1 2.0 1 1 0 1 1 1 0 Glycine rich protein Hydrophobin PF01185.18 EAU87422.1 - 3.5e-27 94.8 7.4 4.3e-27 94.6 7.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EAU87423.1 - 1.9e-26 92.5 7.4 2.4e-26 92.2 7.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin IncD PF17628.2 EAU87423.1 - 0.06 13.1 0.3 0.099 12.4 0.3 1.3 1 0 0 1 1 1 0 Inclusion membrane protein D IglC PF11550.8 EAU87423.1 - 0.23 10.9 2.0 0.99 8.8 0.6 1.9 1 1 1 2 2 2 0 Intracellular growth locus C protein Hydrophobin PF01185.18 EAU87424.1 - 2.4e-27 95.3 9.1 2.9e-27 95.1 9.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 EAU87425.1 - 6.8e-28 97.1 7.7 8.2e-28 96.9 7.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF834 PF05754.14 EAU87425.1 - 0.86 9.7 3.1 6.7 6.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF834) Hydrophobin PF01185.18 EAU87426.1 - 3.2e-23 82.2 9.6 3.9e-23 81.9 9.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Glyco_hydro_61 PF03443.14 EAU87430.2 - 1.2e-50 172.3 0.6 1.8e-50 171.7 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAU87430.2 - 3.4e-11 42.9 12.5 3.4e-11 42.9 12.5 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAU87430.2 - 0.051 13.8 2.0 0.099 12.9 2.0 1.5 1 0 0 1 1 1 0 Toxin 7 DHHC PF01529.20 EAU87431.2 - 3.2e-33 114.7 10.1 6.8e-33 113.6 10.1 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase HemY_N PF07219.13 EAU87431.2 - 0.037 14.2 1.3 5.8 7.2 0.2 2.9 2 1 0 2 2 2 0 HemY protein N-terminus ArAE_1 PF06081.11 EAU87431.2 - 0.38 10.9 4.3 0.82 9.8 4.3 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 Glyco_hydro_61 PF03443.14 EAU87435.1 - 1.3e-59 201.6 0.1 1.6e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 EAU87436.2 - 3.5e-60 203.5 0.0 4.2e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N PF08240.12 EAU87437.2 - 1.9e-28 98.5 0.7 3.5e-28 97.7 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU87437.2 - 5.9e-13 48.9 0.0 1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU87437.2 - 0.00012 23.2 0.0 0.00024 22.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoLip_ATPase_C PF16212.5 EAU87439.2 - 1.4 8.7 18.8 2.6 7.7 18.1 1.7 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal ATG16 PF08614.11 EAU87440.1 - 0.33 11.2 23.7 0.094 12.9 1.6 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 EAU87442.1 - 0.00087 19.8 0.4 0.00087 19.8 0.4 1.6 2 0 0 2 2 2 1 Fez1 YabA PF06156.13 EAU87442.1 - 0.0042 17.7 2.2 0.009 16.6 2.2 1.6 1 0 0 1 1 1 1 Initiation control protein YabA Spc7 PF08317.11 EAU87442.1 - 0.031 13.1 3.5 0.054 12.4 3.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 EAU87442.1 - 0.077 10.5 4.6 0.11 10.0 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prok-RING_4 PF14447.6 EAU87442.1 - 0.18 11.7 1.5 0.38 10.6 1.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FAM76 PF16046.5 EAU87442.1 - 0.26 10.6 16.9 0.034 13.5 5.4 3.1 3 0 0 3 3 3 0 FAM76 protein RP-C_C PF11800.8 EAU87442.1 - 0.48 10.5 2.0 8.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Sas6_CC PF18594.1 EAU87442.1 - 1.4 8.8 5.2 0.14 11.9 1.0 1.6 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain DivIC PF04977.15 EAU87442.1 - 1.5 8.6 7.1 3.8 7.4 7.1 1.7 1 0 0 1 1 1 0 Septum formation initiator Radial_spoke PF04712.12 EAU87442.1 - 8.9 5.1 18.1 0.28 10.1 10.4 2.0 2 0 0 2 2 2 0 Radial spokehead-like protein adh_short PF00106.25 EAU87444.1 - 1e-25 90.3 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU87444.1 - 6.9e-12 45.4 0.1 8.9e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU87444.1 - 1.2e-08 35.1 0.9 2e-08 34.3 0.9 1.3 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.15 EAU87444.1 - 0.014 15.3 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus THF_DHG_CYH_C PF02882.19 EAU87444.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.6 EAU87444.1 - 0.049 13.5 1.6 0.2 11.5 1.7 1.9 1 1 0 1 1 1 0 NAD(P)H-binding NAD_binding_7 PF13241.6 EAU87444.1 - 0.097 13.1 0.0 1.9 8.9 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 EAU87444.1 - 0.13 12.2 0.4 0.33 10.9 0.1 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Glyco_trans_4_4 PF13579.6 EAU87444.1 - 0.14 12.5 1.4 0.63 10.5 1.4 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Phosphorylase PF00343.20 EAU87445.2 - 5e-297 987.0 0.0 5.8e-297 986.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 EAU87446.1 - 2.8e-58 197.4 0.0 7.5e-58 196.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87446.1 - 9.1e-30 103.8 0.0 5.6e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU87446.1 - 0.0023 17.3 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAU87446.1 - 0.0061 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EAU87446.1 - 0.078 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 EAU87447.2 - 7.1e-15 55.2 3.3 5.4e-05 23.9 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU87447.2 - 1.7e-07 31.5 0.0 0.14 12.5 0.0 4.6 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain STE PF02200.16 EAU87448.2 - 2.9e-46 156.4 0.0 4.9e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EAU87448.2 - 9.1e-10 38.5 12.8 2.1e-05 24.7 2.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU87448.2 - 2e-07 31.1 12.9 6.6e-07 29.5 5.3 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU87448.2 - 3.7e-07 30.4 10.2 0.001 19.7 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EAU87448.2 - 0.0013 18.7 1.0 0.0013 18.7 1.0 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EAU87448.2 - 0.0067 16.7 0.7 0.013 15.8 0.7 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 EAU87448.2 - 0.013 15.9 9.6 0.56 10.7 1.4 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 EAU87448.2 - 0.03 14.6 4.9 0.38 11.1 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EAU87448.2 - 0.95 9.8 3.4 2.1 8.7 1.9 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EAU87448.2 - 1.4 9.4 5.9 1.4 9.4 1.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 EAU87448.2 - 5.4 6.7 4.7 4.9 6.9 0.4 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Tad PF13400.6 EAU87449.2 - 0.044 14.1 2.9 0.084 13.2 2.9 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Herpes_gE PF02480.16 EAU87449.2 - 0.064 12.0 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1378 PF07125.11 EAU87449.2 - 0.22 11.7 0.1 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) Gram_pos_anchor PF00746.21 EAU87450.2 - 0.028 14.4 0.4 0.056 13.4 0.4 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Anoctamin PF04547.12 EAU87450.2 - 0.15 10.8 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel FixQ PF05545.11 EAU87450.2 - 0.21 11.6 0.6 0.32 11.0 0.6 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Rax2 PF12768.7 EAU87451.2 - 0.0031 17.0 0.0 0.0075 15.8 0.0 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Cadherin_C_2 PF16492.5 EAU87451.2 - 0.0039 17.9 0.0 0.0097 16.6 0.0 1.6 1 0 0 1 1 1 1 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 EAU87451.2 - 0.24 11.3 0.7 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family Aldo_ket_red PF00248.21 EAU87452.2 - 1.9e-73 247.3 0.0 2.1e-73 247.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT_2 PF13279.6 EAU87456.1 - 0.0008 19.9 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase_fungal PF17667.1 EAU87457.2 - 1.7e-49 168.7 0.0 2.5e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU87457.2 - 0.0018 17.7 0.0 0.0046 16.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain zf-AD PF07776.15 EAU87460.2 - 0.08 13.2 1.0 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Serglycin PF04360.12 EAU87462.2 - 0.0044 17.0 9.9 28 4.6 0.0 7.3 4 3 4 8 8 8 2 Serglycin MARVEL PF01284.23 EAU87463.1 - 0.00076 19.5 10.2 0.019 15.0 4.6 2.2 2 0 0 2 2 2 2 Membrane-associating domain TMEM132D_C PF15706.5 EAU87463.1 - 0.082 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term COX14 PF14880.6 EAU87463.1 - 0.082 12.8 0.0 0.98 9.3 0.0 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF3290 PF11694.8 EAU87463.1 - 0.082 12.9 0.2 0.082 12.9 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ni_hydr_CYTB PF01292.20 EAU87463.1 - 1.7 8.2 13.5 1.2e+02 2.2 13.5 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Ctr PF04145.15 EAU87464.1 - 3.8e-29 102.2 0.5 5.1e-29 101.8 0.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family CCDC24 PF15669.5 EAU87464.1 - 0.0044 16.9 0.0 0.0059 16.5 0.0 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Methyltransf_22 PF13383.6 EAU87466.2 - 5.2e-19 68.8 0.0 6.4e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EAU87466.2 - 2.3e-09 37.5 0.0 3.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain CAP59_mtransfer PF11735.8 EAU87467.2 - 2.9e-69 233.4 0.0 3.6e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Tubulin_3 PF14881.6 EAU87470.2 - 8e-32 110.4 0.0 1.1e-30 106.7 0.0 2.1 2 0 0 2 2 2 1 Tubulin domain Gti1_Pac2 PF09729.9 EAU87471.1 - 5e-30 104.9 0.3 9.8e-26 90.9 0.2 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family AIM3 PF17096.5 EAU87471.1 - 0.06 14.3 0.1 0.06 14.3 0.1 1.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 HsbA PF12296.8 EAU87472.1 - 5.4e-09 36.5 0.1 7.1e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Pkinase_Tyr PF07714.17 EAU87473.2 - 3.1e-51 174.2 0.0 4.6e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU87473.2 - 1.6e-37 129.3 0.0 9.7e-25 87.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 EAU87473.2 - 0.00037 20.2 0.2 0.0056 16.3 0.0 2.5 3 0 0 3 3 3 1 RIO1 family RPT PF13446.6 EAU87473.2 - 0.00039 20.3 0.2 0.0011 18.9 0.2 1.7 1 0 0 1 1 1 1 A repeated domain in UCH-protein Kdo PF06293.14 EAU87473.2 - 0.00046 19.6 0.0 0.0009 18.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU87473.2 - 0.013 15.4 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FAT PF02259.23 EAU87473.2 - 0.034 13.4 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 FAT domain O-FucT PF10250.9 EAU87475.2 - 0.0026 17.5 0.0 0.0069 16.1 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Peptidase_M43 PF05572.13 EAU87477.2 - 1.1e-15 57.9 0.0 1.8e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87477.2 - 8.5e-05 22.8 0.0 0.00024 21.3 0.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU87477.2 - 0.00016 22.2 0.0 0.00055 20.4 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU87477.2 - 0.012 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87477.2 - 0.045 13.6 0.4 0.1 12.4 0.3 1.3 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 EAU87477.2 - 0.059 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-zincin QLQ PF08880.11 EAU87477.2 - 0.07 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 QLQ Peptidase_M66 PF10462.9 EAU87477.2 - 0.17 10.8 0.4 0.34 9.8 0.3 1.5 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M54 PF07998.11 EAU87477.2 - 0.22 11.5 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 p450 PF00067.22 EAU87478.1 - 2.6e-69 234.2 0.0 3.7e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ALO PF04030.14 EAU87478.1 - 0.19 11.5 0.2 8.2 6.1 0.0 2.2 2 0 0 2 2 2 0 D-arabinono-1,4-lactone oxidase Peptidase_M43 PF05572.13 EAU87479.1 - 8.2e-19 68.0 0.0 1.3e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87479.1 - 1.1e-06 29.0 0.0 2.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU87479.1 - 0.00023 21.7 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU87479.1 - 0.00032 20.4 0.0 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EAU87479.1 - 0.0086 16.0 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87479.1 - 0.043 13.7 0.1 0.068 13.0 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.8 EAU87479.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase ABC_tran PF00005.27 EAU87480.2 - 2.8e-53 180.1 0.0 1.6e-30 106.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAU87480.2 - 9.7e-27 94.3 12.1 3.1e-16 59.8 0.8 3.8 4 1 1 5 5 5 2 ABC transporter transmembrane region T2SSE PF00437.20 EAU87480.2 - 5.1e-07 29.0 0.5 0.0015 17.6 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 EAU87480.2 - 8.8e-07 28.6 0.0 0.018 14.5 0.2 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU87480.2 - 6.8e-06 25.7 0.4 0.14 11.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EAU87480.2 - 7.7e-05 22.6 3.2 0.46 10.2 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EAU87480.2 - 0.00024 21.5 0.4 1.1 9.6 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EAU87480.2 - 0.00036 20.2 0.3 0.23 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EAU87480.2 - 0.00072 20.1 7.5 0.0011 19.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 EAU87480.2 - 0.027 14.6 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 EAU87480.2 - 0.029 14.3 0.1 12 5.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EAU87480.2 - 0.09 13.1 2.2 22 5.3 0.1 3.6 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 EAU87480.2 - 0.12 11.6 0.1 10 5.4 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.23 EAU87480.2 - 0.15 12.1 0.1 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 EAU87480.2 - 0.27 11.1 0.9 7.9 6.4 0.0 3.1 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 EAU87480.2 - 1.1 8.4 3.0 1.3 8.2 0.1 2.4 3 0 0 3 3 3 0 NB-ARC domain TPR_19 PF14559.6 EAU87481.2 - 1.3e-08 35.2 0.8 0.43 11.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU87481.2 - 5.8e-06 26.0 6.0 0.93 9.8 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU87481.2 - 2.5e-05 23.9 1.2 7.3 6.6 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU87481.2 - 0.00011 22.0 7.2 2.7 8.2 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU87481.2 - 0.00028 20.9 0.9 0.41 11.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAU87481.2 - 0.0015 19.0 3.9 42 5.1 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU87481.2 - 0.0029 17.9 5.3 6.3 7.2 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU87481.2 - 0.018 15.3 1.4 25 5.2 0.1 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EAU87481.2 - 0.019 15.8 8.3 3.9 8.6 0.3 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAU87481.2 - 0.02 15.2 1.1 2.8 8.5 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAU87481.2 - 0.76 10.5 3.3 1.7e+02 3.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU87482.2 - 5.1e-06 26.7 4.1 2.2e-05 24.6 0.4 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU87482.2 - 0.0035 17.4 5.1 0.45 10.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU87482.2 - 0.0092 15.9 0.8 0.19 11.9 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU87482.2 - 0.012 15.4 0.3 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Ndc1_Nup PF09531.10 EAU87482.2 - 0.019 13.7 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MSA-2c PF12238.8 EAU87482.2 - 0.052 13.6 4.0 0.089 12.8 4.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c TPR_2 PF07719.17 EAU87482.2 - 0.15 12.3 5.3 0.63 10.3 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Totivirus_coat PF05518.11 EAU87482.2 - 2.8 5.9 4.4 5.8 4.8 4.4 1.4 1 0 0 1 1 1 0 Totivirus coat protein Pkinase_fungal PF17667.1 EAU87483.2 - 1e-47 162.9 0.0 1.3e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU87483.2 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU87484.2 - 5.9e-44 150.5 0.0 8.3e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU87484.2 - 0.00037 19.9 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87484.2 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase p450 PF00067.22 EAU87485.1 - 2.5e-68 230.9 0.0 3.6e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tetraspanin PF00335.20 EAU87486.1 - 0.048 13.4 9.2 0.14 11.9 9.1 1.7 1 1 1 2 2 2 0 Tetraspanin family DUF4059 PF13268.6 EAU87486.1 - 0.054 13.9 0.2 0.054 13.9 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) HIG_1_N PF04588.13 EAU87486.1 - 0.093 13.0 1.4 10 6.4 0.0 3.4 3 0 0 3 3 3 0 Hypoxia induced protein conserved region DHHC PF01529.20 EAU87486.1 - 0.7 10.0 9.8 6.3 6.9 0.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Peptidase_M43 PF05572.13 EAU87488.2 - 1.5e-16 60.6 0.4 2.4e-16 60.0 0.4 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87488.2 - 0.00037 20.7 0.0 0.00068 19.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 EAU87488.2 - 0.0034 17.0 0.3 0.0057 16.3 0.3 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 EAU87488.2 - 0.0034 17.9 0.1 0.017 15.6 0.1 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87488.2 - 0.017 15.0 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.6 EAU87488.2 - 0.047 13.3 0.4 0.085 12.5 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SLC12 PF03522.15 EAU87490.2 - 1.4 7.9 11.6 1.8 7.5 11.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 EAU87490.2 - 1.6 6.9 24.1 1.8 6.7 24.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EAU87490.2 - 4.1 7.1 17.8 6.2 6.6 17.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 EAU87490.2 - 5.3 7.1 37.3 10 6.2 37.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pkinase PF00069.25 EAU87492.1 - 3.5e-11 43.0 0.0 1.1e-09 38.1 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain APH PF01636.23 EAU87492.1 - 6e-05 23.1 0.0 0.00014 21.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAU87492.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAU87492.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAU87492.1 - 0.0017 17.2 0.0 0.0022 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EAU87492.1 - 0.003 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EAU87492.1 - 0.0041 16.7 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EAU87492.1 - 0.15 11.1 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EAU87492.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like OTU PF02338.19 EAU87496.1 - 3.6e-14 53.4 0.0 5.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3915 PF13054.6 EAU87496.1 - 1.3 9.0 3.9 0.42 10.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) IHABP4_N PF16174.5 EAU87496.1 - 3.4 8.3 13.9 0.15 12.7 4.9 2.7 2 1 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal TRAP_alpha PF03896.16 EAU87498.1 - 0.17 11.1 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1180 PF06679.12 EAU87498.1 - 0.32 11.4 0.0 0.32 11.4 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1996 PF09362.10 EAU87499.2 - 7.5e-68 229.0 0.1 9.9e-68 228.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 EAU87500.2 - 6.4e-05 23.1 0.2 7.8e-05 22.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) F-box-like PF12937.7 EAU87502.2 - 6.6e-06 25.9 0.5 0.0001 22.1 0.1 3.1 2 1 0 2 2 2 1 F-box-like REV PF00424.18 EAU87502.2 - 0.78 9.8 3.8 3.6 7.7 1.2 3.1 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) F-box-like PF12937.7 EAU87503.2 - 0.021 14.7 6.4 0.05 13.5 2.4 3.5 3 1 0 3 3 3 0 F-box-like Plavaka PF18759.1 EAU87504.2 - 1.7e-41 142.6 0.0 1.9e-39 135.8 0.0 2.2 1 1 0 1 1 1 1 Plavaka transposase Ish1 PF10281.9 EAU87505.2 - 0.04 14.2 0.2 0.2 12.0 0.1 2.3 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Vma12 PF11712.8 EAU87505.2 - 0.095 12.8 1.0 2.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YabA PF06156.13 EAU87505.2 - 1.3 9.7 5.7 4.6 7.9 5.7 1.9 1 0 0 1 1 1 0 Initiation control protein YabA DUF2570 PF10828.8 EAU87505.2 - 5.8 6.8 9.1 12 5.7 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) F-box-like PF12937.7 EAU87506.2 - 4.9e-08 32.7 0.4 3.6e-07 30.0 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU87506.2 - 0.28 11.7 6.1 0.14 12.6 0.7 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_transf_20 PF00982.21 EAU87507.2 - 7.1e-133 443.7 0.0 1e-132 443.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EAU87507.2 - 5.3e-21 74.8 0.0 9.5e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 EAU87507.2 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain F-box-like PF12937.7 EAU87508.2 - 1e-10 41.3 0.1 2.5e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.13 EAU87508.2 - 0.091 13.5 1.9 0.4 11.4 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich Repeat F-box PF00646.33 EAU87508.2 - 0.26 11.2 2.7 0.84 9.6 0.3 3.1 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 EAU87511.2 - 2.3e-07 30.6 0.0 1.8e-05 24.5 0.0 3.0 2 1 0 2 2 2 1 F-box-like AAA_12 PF13087.6 EAU87511.2 - 0.008 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain F-box-like PF12937.7 EAU87512.2 - 6.4e-08 32.4 0.0 1.8e-06 27.8 0.0 2.8 2 1 0 2 2 2 1 F-box-like Aldo_ket_red PF00248.21 EAU87515.1 - 4.5e-36 124.5 0.0 1.5e-35 122.9 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Isochorismatase PF00857.20 EAU87516.2 - 1.3e-15 58.1 0.2 1.5e-15 57.8 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family Spore_GerQ PF09671.10 EAU87516.2 - 0.043 13.8 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) DUF4436 PF14494.6 EAU87517.2 - 0.00031 20.1 2.6 0.0005 19.5 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) MT-A70 PF05063.14 EAU87518.2 - 1.4e-40 139.0 0.0 2.4e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 EAU87518.2 - 0.052 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 EAU87518.2 - 0.23 11.1 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Kelch_4 PF13418.6 EAU87519.2 - 1.5e-38 130.5 8.8 4.9e-06 26.4 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EAU87519.2 - 2.4e-33 113.5 1.7 5.2e-07 29.5 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EAU87519.2 - 3.7e-31 106.5 1.9 6.9e-05 22.3 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EAU87519.2 - 2.3e-27 94.3 8.0 0.00017 21.7 0.1 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EAU87519.2 - 5e-27 92.8 4.3 0.00033 20.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EAU87519.2 - 1.8e-22 79.1 15.6 4.5e-07 30.0 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Peptidase_C14 PF00656.22 EAU87520.2 - 7.4e-18 65.4 0.0 3.4e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Caspase domain Fez1 PF06818.15 EAU87520.2 - 0.0012 19.3 1.9 0.0023 18.4 1.9 1.3 1 0 0 1 1 1 1 Fez1 CdvA PF18822.1 EAU87520.2 - 0.17 11.7 2.1 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Zein-binding PF04576.15 EAU87520.2 - 0.33 11.2 2.8 0.74 10.1 2.8 1.5 1 0 0 1 1 1 0 Zein-binding Glyco_hydro_28 PF00295.17 EAU87521.2 - 9.4e-40 136.6 0.6 1.3e-39 136.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Mucin PF01456.17 EAU87523.1 - 0.0091 16.0 11.8 3.7 7.6 0.0 2.5 2 0 0 2 2 2 2 Mucin-like glycoprotein Noc2 PF03715.13 EAU87524.1 - 2.2e-112 375.2 0.1 8.7e-112 373.2 0.0 1.9 2 0 0 2 2 2 1 Noc2p family HSP70 PF00012.20 EAU87526.2 - 0.024 12.8 0.0 0.13 10.4 0.0 2.1 2 1 0 2 2 2 0 Hsp70 protein ALO PF04030.14 EAU87527.2 - 4.9e-74 249.4 0.7 6.2e-74 249.1 0.7 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EAU87527.2 - 8.3e-29 100.1 0.2 1.3e-28 99.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.26 EAU87528.2 - 4e-13 49.2 0.0 3.3e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RNA_pol_Rpb2_6 PF00562.28 EAU87529.2 - 1.2e-121 406.4 0.2 6.3e-121 404.1 0.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EAU87529.2 - 1.3e-56 191.3 0.1 2.1e-56 190.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EAU87529.2 - 1.1e-31 109.0 0.3 3.1e-31 107.6 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EAU87529.2 - 2.6e-29 102.2 0.1 6.5e-29 100.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EAU87529.2 - 4.2e-27 94.2 3.1 2e-26 92.0 1.7 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EAU87529.2 - 5.3e-20 71.4 0.4 1.4e-19 70.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EAU87529.2 - 4.2e-10 40.0 2.2 1.3e-09 38.4 2.2 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 UQ_con PF00179.26 EAU87530.2 - 4.4e-46 156.0 0.0 5e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAU87530.2 - 0.012 15.3 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B SNF2_N PF00176.23 EAU87531.2 - 5.5e-44 150.3 0.1 2.6e-43 148.1 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EAU87531.2 - 2.2e-06 27.8 0.2 1.8e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAU87531.2 - 0.0055 17.0 0.0 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EAU87531.2 - 0.016 14.9 0.0 0.13 11.9 0.0 2.4 3 0 0 3 3 3 0 SWI2/SNF2 ATPase VIGSSK PF14773.6 EAU87531.2 - 0.02 15.0 0.0 0.02 15.0 0.0 2.9 2 0 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal Peptidase_C65 PF10275.9 EAU87532.2 - 1e-47 162.7 0.0 1.8e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase C65 Otubain K1377 PF15352.6 EAU87532.2 - 0.0045 15.4 1.5 0.006 14.9 1.5 1.1 1 0 0 1 1 1 1 Susceptibility to monomelic amyotrophy Nup192 PF11894.8 EAU87534.1 - 9.5e-242 805.4 0.0 1.2e-241 805.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 aGPT-Pplase1 PF18723.1 EAU87535.2 - 4.6e-97 324.8 0.3 6.1e-97 324.4 0.3 1.1 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 EAU87535.2 - 1e-08 35.0 0.7 2.5e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Plavaka PF18759.1 EAU87536.2 - 4.1e-42 144.5 0.1 1.2e-41 143.1 0.0 1.7 2 0 0 2 2 2 1 Plavaka transposase Cast PF10174.9 EAU87537.1 - 2.5e-06 26.1 26.1 3.2e-06 25.7 26.1 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Ribophorin_II PF05817.14 EAU87537.1 - 0.53 8.8 4.1 0.72 8.3 2.4 1.8 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II MscS_porin PF12795.7 EAU87537.1 - 0.89 9.0 28.7 0.027 14.0 11.0 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain TMPIT PF07851.13 EAU87537.1 - 1.8 7.7 14.6 0.22 10.7 5.0 2.1 2 0 0 2 2 2 0 TMPIT-like protein ATG16 PF08614.11 EAU87537.1 - 2.3 8.4 36.5 0.13 12.5 16.4 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CtIP_N PF10482.9 EAU87537.1 - 2.6 8.1 22.1 1.6 8.8 8.0 3.0 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Septin PF00735.18 EAU87538.2 - 1.4e-05 24.5 0.1 6.4e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Septin AIG1 PF04548.16 EAU87538.2 - 1.8e-05 24.2 0.1 3.8e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 EAU87538.2 - 2.4e-05 24.4 0.1 9.3e-05 22.5 0.1 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAU87538.2 - 0.002 18.5 0.7 0.0055 17.1 0.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EAU87538.2 - 0.006 16.1 0.0 0.015 14.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 EAU87538.2 - 0.02 15.3 0.3 0.049 14.1 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EAU87538.2 - 0.027 14.4 0.6 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EAU87538.2 - 0.028 14.1 0.3 0.053 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EAU87538.2 - 0.03 14.1 0.5 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAU87538.2 - 0.032 14.5 0.1 0.087 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EAU87538.2 - 0.032 14.8 0.5 0.76 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4972 PF16342.5 EAU87538.2 - 0.033 13.9 1.0 0.056 13.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Roc PF08477.13 EAU87538.2 - 0.097 12.9 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Uso1_p115_C PF04871.13 EAU87538.2 - 0.2 12.1 7.2 0.33 11.3 7.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region AAA_19 PF13245.6 EAU87538.2 - 0.27 11.6 1.2 0.64 10.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain EMC3_TMCO1 PF01956.16 EAU87538.2 - 0.6 9.8 2.2 1.1 9.0 2.2 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Dynamin_N PF00350.23 EAU87538.2 - 0.63 10.1 7.2 10 6.2 0.2 3.3 2 2 1 3 3 3 0 Dynamin family FapA PF03961.13 EAU87538.2 - 1.1 7.8 5.5 1.7 7.2 5.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TSC22 PF01166.18 EAU87538.2 - 1.4 9.3 5.0 8.1 6.8 0.1 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family AAA_23 PF13476.6 EAU87538.2 - 1.8 9.0 4.3 2.5 8.5 1.3 2.0 2 0 0 2 2 2 0 AAA domain Tho2 PF11262.8 EAU87538.2 - 2.1 7.5 4.1 3 7.0 4.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF2205 PF10224.9 EAU87538.2 - 2.5 8.1 6.3 7.7 6.6 1.1 2.3 1 1 1 2 2 2 0 Short coiled-coil protein zf-MYND PF01753.18 EAU87540.2 - 6.3e-06 26.2 16.5 0.00029 20.9 3.5 3.4 3 1 1 4 4 4 2 MYND finger zf-Mss51 PF13824.6 EAU87540.2 - 0.64 10.2 2.5 2.9 8.0 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Paramyx_P_V_C PF03210.13 EAU87541.1 - 0.044 13.6 0.7 0.08 12.7 0.7 1.3 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal MMR_HSR1 PF01926.23 EAU87543.2 - 1.1e-11 44.8 0.0 3.4e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU87543.2 - 3.1e-11 43.0 0.0 3.1e-11 43.0 0.0 2.5 3 0 0 3 3 3 1 AIG1 family RsgA_GTPase PF03193.16 EAU87543.2 - 1.9e-07 31.2 0.0 6.5e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EAU87543.2 - 2.2e-06 27.3 0.2 1.6e-05 24.4 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EAU87543.2 - 1.3e-05 25.3 9.7 0.00017 21.7 0.3 3.9 2 2 1 4 4 4 2 Dynamin family Gtr1_RagA PF04670.12 EAU87543.2 - 5.2e-05 22.7 0.0 0.00017 21.1 0.0 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 EAU87543.2 - 0.00087 19.8 0.0 0.00087 19.8 0.0 3.4 3 2 0 3 3 3 1 ABC transporter SRPRB PF09439.10 EAU87543.2 - 0.0017 17.9 0.0 0.0017 17.9 0.0 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Septin PF00735.18 EAU87543.2 - 0.0025 17.1 0.0 0.0078 15.5 0.0 1.8 1 0 0 1 1 1 1 Septin GAS PF13851.6 EAU87543.2 - 0.008 15.5 39.2 0.81 9.0 6.1 4.9 2 1 3 5 5 5 3 Growth-arrest specific micro-tubule binding Auts2 PF15336.6 EAU87543.2 - 0.017 15.2 0.3 0.017 15.2 0.3 2.5 3 0 0 3 3 2 0 Autism susceptibility gene 2 protein GTP_EFTU PF00009.27 EAU87543.2 - 0.019 14.5 1.3 0.057 12.9 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EAU87543.2 - 0.019 14.7 0.3 0.046 13.5 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIG-L PF02585.17 EAU87543.2 - 0.022 15.4 0.0 5 7.8 0.0 2.8 1 1 0 2 2 2 0 GlcNAc-PI de-N-acetylase Roc PF08477.13 EAU87543.2 - 0.12 12.6 0.3 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SMC_N PF02463.19 EAU87543.2 - 0.27 10.7 3.6 0.22 10.9 0.2 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain HOOK PF05622.12 EAU87543.2 - 0.36 8.9 36.9 0.66 8.0 36.9 1.3 1 0 0 1 1 1 0 HOOK protein AAA_23 PF13476.6 EAU87543.2 - 0.37 11.3 0.1 0.37 11.3 0.1 3.6 2 1 0 2 2 1 0 AAA domain MAD PF05557.13 EAU87543.2 - 0.45 8.8 42.6 0.2 10.0 19.6 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Spc7 PF08317.11 EAU87543.2 - 0.74 8.6 37.7 0.51 9.2 16.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Guanylate_kin PF00625.21 EAU87543.2 - 0.8 9.4 0.0 0.8 9.4 0.0 3.2 3 0 0 3 3 3 0 Guanylate kinase AAA_16 PF13191.6 EAU87543.2 - 1.5 9.2 0.0 1.5 9.2 0.0 3.2 2 1 0 2 2 1 0 AAA ATPase domain Seryl_tRNA_N PF02403.22 EAU87543.2 - 1.5 9.1 32.7 0.078 13.2 1.9 4.4 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 EAU87543.2 - 1.5 8.9 51.2 0.34 11.0 7.2 4.2 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein TFR_dimer PF04253.15 EAU87543.2 - 1.6 8.9 5.8 5.7 7.1 0.3 3.7 4 0 0 4 4 4 0 Transferrin receptor-like dimerisation domain FtsK_SpoIIIE PF01580.18 EAU87543.2 - 5.8 6.2 7.5 0.99 8.7 0.3 2.7 2 1 0 3 3 3 0 FtsK/SpoIIIE family PMEI PF04043.15 EAU87543.2 - 8.8 6.7 11.9 0.052 13.9 2.3 2.1 2 1 0 2 2 1 0 Plant invertase/pectin methylesterase inhibitor KASH_CCD PF14662.6 EAU87543.2 - 9.1 6.1 42.5 2.4 7.9 18.2 3.3 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH AIG1 PF04548.16 EAU87544.1 - 7.8e-13 48.2 0.1 7.8e-13 48.2 0.1 2.1 3 0 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.23 EAU87544.1 - 6e-10 39.2 0.1 1.7e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU87544.1 - 2.2e-05 24.4 0.2 6.8e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EAU87544.1 - 7.3e-05 22.3 0.1 0.00019 21.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EAU87544.1 - 0.00039 20.9 5.1 0.00048 20.6 0.0 2.7 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 EAU87544.1 - 0.012 15.7 12.5 0.017 15.2 0.1 3.9 4 2 1 5 5 5 0 Dynamin family SRPRB PF09439.10 EAU87544.1 - 0.022 14.2 0.8 0.068 12.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAU87544.1 - 0.023 14.2 0.6 0.19 11.3 0.6 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAU87544.1 - 0.027 13.8 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.18 EAU87544.1 - 0.039 13.2 0.0 0.097 11.9 0.0 1.6 1 0 0 1 1 1 0 Septin DinB_2 PF12867.7 EAU87544.1 - 0.066 13.7 5.4 0.43 11.1 0.2 3.2 3 1 0 3 3 3 0 DinB superfamily Golgin_A5 PF09787.9 EAU87544.1 - 0.35 10.3 23.4 0.43 10.0 8.1 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 EAU87544.1 - 0.49 9.7 18.7 1.3 8.4 9.1 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CP12 PF02672.15 EAU87544.1 - 0.78 10.5 3.6 4.3 8.2 0.1 3.7 3 1 1 4 4 4 0 CP12 domain GIT_CC PF16559.5 EAU87544.1 - 1.1 9.2 8.6 7.8 6.5 0.1 4.0 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5101 PF17031.5 EAU87544.1 - 1.1 9.3 4.5 5 7.3 0.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5101) MbeD_MobD PF04899.12 EAU87544.1 - 9.6 6.4 10.6 0.39 10.9 0.3 3.2 2 1 1 3 3 3 0 MbeD/MobD like Acetyltransf_1 PF00583.25 EAU87547.2 - 1.3e-14 54.4 0.0 1.8e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU87547.2 - 2.7e-09 37.0 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU87547.2 - 2.8e-09 37.3 0.0 4.2e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU87547.2 - 9.4e-08 31.9 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EAU87547.2 - 0.00013 22.7 0.0 0.00017 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAU87547.2 - 0.00046 20.3 0.0 0.00078 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EAU87547.2 - 0.00065 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAU87547.2 - 0.0015 18.7 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 EAU87548.1 - 6.7e-05 21.9 2.6 0.04 12.7 0.3 2.2 2 0 0 2 2 2 2 Amino acid permease HSP70 PF00012.20 EAU87549.2 - 5e-250 830.8 7.6 8.1e-250 830.1 7.6 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAU87549.2 - 2.5e-22 79.1 0.5 5.1e-21 74.8 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EAU87549.2 - 0.0011 18.0 0.4 0.038 13.0 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EAU87549.2 - 0.056 12.7 0.2 0.14 11.4 0.2 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase HOIP-UBA PF16678.5 EAU87549.2 - 0.088 12.8 0.3 0.42 10.6 0.0 2.2 2 0 0 2 2 2 0 HOIP UBA domain pair Spectrin PF00435.21 EAU87549.2 - 0.28 11.7 8.8 1.8 9.1 0.2 3.5 3 0 0 3 3 3 0 Spectrin repeat DUF948 PF06103.11 EAU87549.2 - 2.9 8.2 4.1 48 4.3 0.2 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FtsA PF14450.6 EAU87549.2 - 3.4 8.1 6.2 38 4.8 0.1 3.4 3 2 0 3 3 3 0 Cell division protein FtsA HMMR_N PF15905.5 EAU87550.2 - 0.0085 15.6 5.1 0.012 15.1 5.1 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal LUC7 PF03194.15 EAU87550.2 - 0.0091 15.7 1.3 0.014 15.1 1.3 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Dynamin_N PF00350.23 EAU87550.2 - 0.014 15.5 0.7 0.046 13.8 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Noelin-1 PF12308.8 EAU87550.2 - 0.26 11.3 3.0 0.56 10.2 3.0 1.4 1 0 0 1 1 1 0 Neurogenesis glycoprotein PCRF PF03462.18 EAU87550.2 - 0.36 10.7 4.0 0.72 9.7 4.0 1.4 1 0 0 1 1 1 0 PCRF domain Seryl_tRNA_N PF02403.22 EAU87550.2 - 0.48 10.7 5.7 0.89 9.8 5.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TauD PF02668.16 EAU87552.1 - 2.1e-61 208.1 0.3 2.5e-61 207.8 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transmemb_17 PF09799.9 EAU87553.2 - 0.74 10.4 10.0 0.11 13.0 5.2 2.2 2 1 0 2 2 2 0 Predicted membrane protein Crust_neurohorm PF01147.17 EAU87554.1 - 0.049 13.4 0.1 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family VHS PF00790.19 EAU87566.2 - 1.5e-09 37.9 0.0 2.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EAU87566.2 - 1.1e-08 35.2 1.0 8.7e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 GAT domain 4HBT PF03061.22 EAU87567.2 - 1.8e-05 25.0 0.0 0.11 12.8 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily MgtC PF02308.16 EAU87568.2 - 0.21 11.9 8.3 0.046 14.1 3.9 2.2 2 0 0 2 2 2 0 MgtC family tRNA-synt_1 PF00133.22 EAU87569.1 - 1e-33 116.5 0.0 1.8e-16 59.5 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAU87569.1 - 4.8e-15 55.8 0.2 1.6e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAU87569.1 - 1.5e-14 53.5 0.0 4.9e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EAU87569.1 - 4.7e-07 29.5 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain HMG_box PF00505.19 EAU87573.2 - 7.5e-24 83.9 1.9 7.5e-24 83.9 1.9 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU87573.2 - 4.1e-19 68.9 1.4 4.1e-19 68.9 1.4 1.7 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.13 EAU87573.2 - 0.00089 19.9 1.1 0.00089 19.9 1.1 2.0 1 1 1 2 2 2 1 YABBY protein CHDNT PF08073.12 EAU87573.2 - 0.0013 18.7 0.0 0.0028 17.6 0.0 1.5 2 0 0 2 2 2 1 CHDNT (NUC034) domain Protamine_like PF06382.11 EAU87573.2 - 0.012 15.8 0.4 0.015 15.5 0.4 1.2 1 0 0 1 1 1 0 Protamine and protamine like Oxysterol_BP PF01237.18 EAU87574.2 - 6.1e-53 180.0 6.9 3.7e-45 154.4 0.0 2.9 2 1 0 2 2 2 2 Oxysterol-binding protein SAB PF04382.13 EAU87580.2 - 0.0036 17.3 1.5 0.01 15.9 0.0 2.3 2 0 0 2 2 2 1 SAB domain CxC2 PF18803.1 EAU87583.2 - 1.8e-29 102.0 0.4 3.4e-29 101.1 0.4 1.4 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU87583.2 - 5.6e-10 39.3 0.1 1.2e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU87583.2 - 2.1e-05 24.4 0.0 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases SnoaL_2 PF12680.7 EAU87594.2 - 5.5e-06 27.0 0.0 7.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 EAU87594.2 - 0.0076 16.4 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain TFIIS_C PF01096.18 EAU87595.2 - 5.3e-15 55.0 0.5 5.3e-15 55.0 0.5 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EAU87595.2 - 2e-09 37.2 0.4 2e-09 37.2 0.4 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EAU87595.2 - 1.6e-05 24.8 1.2 0.084 12.9 0.3 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain IBR PF01485.21 EAU87595.2 - 0.014 15.6 2.4 1.2 9.4 0.6 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zinc-ribbons_6 PF07191.12 EAU87595.2 - 0.031 14.3 3.1 0.33 11.0 0.6 2.2 2 1 0 2 2 2 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.12 EAU87595.2 - 0.097 12.6 6.3 9.2 6.3 0.1 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-TFIIB PF13453.6 EAU87595.2 - 0.15 11.4 5.6 0.22 10.9 0.5 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf_C2H2_10 PF18414.1 EAU87595.2 - 0.64 9.6 0.2 0.64 9.6 0.2 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger zf-H2C2_2 PF13465.6 EAU87595.2 - 0.75 10.3 6.8 5.3 7.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain HypA PF01155.19 EAU87595.2 - 0.75 9.8 2.6 2 8.4 2.6 1.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-Sec23_Sec24 PF04810.15 EAU87595.2 - 1.5 8.9 7.2 0.74 9.9 2.5 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 EAU87595.2 - 1.9 8.0 7.6 5.8 6.5 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_4 PF15227.6 EAU87595.2 - 1.9 8.7 6.9 4.9 7.4 0.4 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Rubredoxin PF00301.20 EAU87595.2 - 4.5 7.4 8.4 6.9 6.8 0.2 3.1 3 0 0 3 3 3 0 Rubredoxin Opy2 PF09463.10 EAU87595.2 - 6.8 7.1 9.6 4.9 7.5 0.1 3.0 2 1 0 2 2 2 0 Opy2 protein Pyridoxal_deC PF00282.19 EAU87596.2 - 1.1e-18 67.2 0.0 7.8e-08 31.4 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EAU87596.2 - 0.0085 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase SPRY PF00622.28 EAU87597.1 - 2.7e-14 53.3 0.0 4.8e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain BTB PF00651.31 EAU87598.2 - 1.2e-09 38.4 0.0 2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain APC1_C PF18122.1 EAU87599.1 - 1.1e-29 103.5 0.0 2.2e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EAU87599.1 - 5e-09 36.8 0.3 2.3e-08 34.6 0.4 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EAU87599.1 - 3.8e-05 23.9 0.9 8.1 7.1 0.2 5.1 4 0 0 4 4 4 1 Proteasome/cyclosome repeat BAG PF02179.16 EAU87601.2 - 6.3e-09 36.1 0.0 6.3e-09 36.1 0.0 2.2 2 1 0 2 2 2 1 BAG domain Stathmin PF00836.19 EAU87601.2 - 0.96 9.4 20.7 2.9 7.9 20.7 1.8 1 0 0 1 1 1 0 Stathmin family Exonuc_VII_L PF02601.15 EAU87601.2 - 3.7 7.0 10.5 5 6.6 10.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Polyketide_cyc2 PF10604.9 EAU87604.2 - 7.4e-06 26.3 0.1 1.6e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EAU87604.2 - 0.023 14.9 0.1 0.05 13.8 0.0 1.6 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EAU87605.1 - 4.2e-10 40.1 1.1 3.5e-09 37.1 1.1 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EAU87605.1 - 3.7e-05 23.9 0.1 5.1e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport p450 PF00067.22 EAU87606.2 - 2.7e-68 230.8 0.0 3.3e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTP_transf_like PF01467.26 EAU87607.2 - 1.7e-26 93.1 0.0 2.5e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DSPc PF00782.20 EAU87608.2 - 3.2e-21 75.5 0.0 1e-20 73.9 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 EAU87608.2 - 4.7e-06 27.1 0.0 2.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain MLTR_LBD PF17765.1 EAU87608.2 - 0.098 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Y_phosphatase PF00102.27 EAU87608.2 - 0.2 11.2 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PIH1 PF08190.12 EAU87609.2 - 9.2e-13 48.0 0.6 5.1e-12 45.6 0.6 2.1 1 1 0 1 1 1 1 PIH1 N-terminal domain DAHP_synth_1 PF00793.20 EAU87610.2 - 7.2e-98 326.8 0.0 8.4e-98 326.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AAA_12 PF13087.6 EAU87611.2 - 1.1e-39 136.2 0.0 2e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU87611.2 - 2.7e-25 89.7 0.3 7.4e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EAU87611.2 - 4.4e-10 40.1 0.0 1.1e-09 38.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU87611.2 - 2.4e-07 30.6 0.0 1.8e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU87611.2 - 0.00022 21.1 1.3 1.3 8.7 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EAU87611.2 - 0.00026 20.6 0.0 0.0014 18.2 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EAU87611.2 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 EAU87611.2 - 0.016 15.2 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EAU87611.2 - 0.018 14.9 0.0 0.23 11.3 0.0 2.7 3 0 0 3 3 3 0 Helicase AAA_16 PF13191.6 EAU87611.2 - 0.029 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 EAU87611.2 - 0.063 12.4 0.0 9.3 5.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase UvrD_C PF13361.6 EAU87611.2 - 0.11 11.8 0.0 2.1 7.7 0.3 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF1365 PF07103.11 EAU87613.2 - 3.9e-57 193.7 0.0 5.1e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) AAA_12 PF13087.6 EAU87614.2 - 4.6e-57 192.9 0.0 9.5e-57 191.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU87614.2 - 6.9e-27 94.9 6.1 7.3e-23 81.7 0.8 2.6 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 EAU87614.2 - 8.5e-12 45.6 1.0 4.3e-11 43.3 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU87614.2 - 1.1e-08 35.1 0.2 2.7e-07 30.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EAU87614.2 - 1.2e-05 25.0 0.4 4.8e-05 23.0 0.4 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EAU87614.2 - 0.0024 17.6 0.0 3.7 7.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 EAU87614.2 - 0.021 14.2 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 EAU87614.2 - 0.051 13.1 0.1 4.7 6.7 0.1 2.4 1 1 1 2 2 2 0 P-loop containing dynein motor region PH_10 PF15411.6 EAU87614.2 - 0.059 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_16 PF13191.6 EAU87614.2 - 0.092 13.1 0.2 0.37 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain zf-RanBP PF00641.18 EAU87615.1 - 1.9e-05 23.9 15.8 0.00046 19.4 2.1 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others LIM PF00412.22 EAU87616.1 - 2.9e-22 78.7 23.3 1.4e-11 44.5 6.6 2.2 2 0 0 2 2 2 2 LIM domain zf-C3HC4_5 PF17121.5 EAU87616.1 - 0.11 12.5 14.2 0.065 13.1 2.9 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PADR1 PF08063.12 EAU87616.1 - 0.33 10.8 0.1 0.33 10.8 0.1 3.8 4 1 0 4 4 4 0 PADR1 (NUC008) domain zf_UBZ PF18439.1 EAU87616.1 - 8.7 6.0 17.0 5.3 6.7 0.2 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger eIF-5a PF01287.20 EAU87617.1 - 1.2e-29 102.1 0.2 1.8e-29 101.6 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EAU87617.1 - 0.0092 16.0 0.1 0.015 15.3 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Bromo_TP PF07524.13 EAU87618.2 - 3.7e-07 30.1 0.2 6.2e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 EAU87618.2 - 4.1 7.8 4.3 0.67 10.3 0.2 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SRAP PF02586.14 EAU87619.2 - 2.7e-65 220.0 0.1 4e-65 219.4 0.1 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) IMPDH PF00478.25 EAU87620.1 - 7.9e-132 439.4 0.1 1.4e-131 438.6 0.1 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EAU87620.1 - 4.3e-15 55.9 0.9 5.2e-08 33.2 0.0 3.0 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 EAU87620.1 - 5.9e-10 38.7 1.3 1.6e-09 37.3 1.1 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase ThiG PF05690.14 EAU87620.1 - 0.00011 21.6 0.8 0.00025 20.5 0.8 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 EAU87620.1 - 0.00017 21.1 12.9 0.0042 16.5 10.1 2.9 2 1 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.21 EAU87620.1 - 0.0005 19.6 2.8 0.0012 18.4 0.9 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein YpsA PF06908.11 EAU87620.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Glu_synthase PF01645.17 EAU87620.1 - 0.25 10.4 4.7 0.71 8.9 4.7 1.7 1 0 0 1 1 1 0 Conserved region in glutamate synthase Dus PF01207.17 EAU87620.1 - 0.43 9.6 1.7 1.5 7.8 0.2 2.1 1 1 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF2263 PF10021.9 EAU87621.1 - 3.6e-38 131.2 0.0 5.3e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) zf-C3HC4_3 PF13920.6 EAU87622.2 - 0.0015 18.3 4.5 0.0015 18.3 4.5 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PARP PF00644.20 EAU87623.2 - 1.1e-08 35.0 0.2 4.9e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 EAU87624.2 - 9.9e-08 31.8 2.4 1.4e-06 28.1 0.6 3.1 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain LAT PF15234.6 EAU87624.2 - 4.1 7.1 5.9 7.1 6.3 4.9 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells PARP PF00644.20 EAU87625.2 - 3.2e-07 30.1 2.1 0.00012 21.7 0.9 2.9 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Syja_N PF02383.18 EAU87629.2 - 2.6e-77 260.3 0.1 3.9e-77 259.7 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain PAN_4 PF14295.6 EAU87630.1 - 0.026 14.4 1.1 0.048 13.6 1.1 1.5 1 0 0 1 1 1 0 PAN domain DEC-1_N PF04625.13 EAU87630.1 - 0.93 8.4 2.7 1.1 8.2 2.7 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RRM_1 PF00076.22 EAU87631.2 - 1.3e-26 92.1 0.3 4.6e-15 55.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU87631.2 - 0.00085 19.4 0.0 0.41 10.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 EAU87631.2 - 0.016 14.9 0.0 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain TFIIA PF03153.13 EAU87631.2 - 2.3 8.1 11.4 0.27 11.2 2.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EAU87631.2 - 2.7 8.6 12.2 5.6 7.6 9.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 EAU87632.1 - 3.3e-47 161.1 0.0 5.1e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87632.1 - 2.9e-46 157.8 0.0 4.1e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EAU87632.1 - 3.2e-07 30.1 1.4 6.7e-07 29.1 1.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.14 EAU87632.1 - 0.003 17.0 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU87632.1 - 0.0044 17.0 0.0 0.0072 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family C1_2 PF03107.16 EAU87632.1 - 0.033 14.5 0.7 0.068 13.5 0.7 1.5 1 0 0 1 1 1 0 C1 domain Haspin_kinase PF12330.8 EAU87632.1 - 0.037 13.0 0.0 0.082 11.8 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain PHD PF00628.29 EAU87632.1 - 0.077 12.9 3.9 0.18 11.7 3.9 1.6 1 0 0 1 1 1 0 PHD-finger TFIIF_alpha PF05793.12 EAU87632.1 - 1 7.9 2.7 1.4 7.4 2.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Axin_b-cat_bind PF08833.10 EAU87633.2 - 8.7 6.5 13.1 0.76 9.9 0.9 4.1 3 1 0 3 3 3 0 Axin beta-catenin binding domain CxC5 PF18718.1 EAU87639.2 - 2.1e-33 114.9 3.9 2.1e-33 114.9 3.9 1.9 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EAU87639.2 - 2.3e-26 91.9 4.8 2.3e-26 91.9 4.8 2.2 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases NopRA1 PF16201.5 EAU87639.2 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 ADK_lid PF05191.14 EAU87639.2 - 2.3 8.3 6.2 2.4 8.2 1.2 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid SUR7 PF06687.12 EAU87640.1 - 1e-12 48.1 12.8 4.2e-12 46.2 12.8 1.8 1 1 0 1 1 1 1 SUR7/PalI family L_HMGIC_fpl PF10242.9 EAU87640.1 - 0.007 16.6 2.3 0.013 15.7 2.3 1.5 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF4381 PF14316.6 EAU87640.1 - 0.022 15.0 0.0 0.022 15.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Claudin_2 PF13903.6 EAU87640.1 - 0.05 13.4 8.7 0.054 13.2 7.3 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1218 PF06749.12 EAU87640.1 - 0.36 11.4 0.3 0.36 11.4 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) OAD_gamma PF04277.13 EAU87640.1 - 0.39 11.3 0.0 0.39 11.3 0.0 3.0 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain PhoLip_ATPase_C PF16212.5 EAU87640.1 - 1.3 8.7 8.5 0.073 12.8 3.4 1.4 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal DuoxA PF10204.9 EAU87640.1 - 6.6 5.6 10.2 0.07 12.1 2.6 1.5 2 0 0 2 2 2 0 Dual oxidase maturation factor Ish1 PF10281.9 EAU87641.2 - 5.9e-57 189.7 37.7 2.7e-10 40.4 2.9 8.0 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EAU87641.2 - 1.2e-05 24.9 3.2 7.3 6.4 0.0 5.2 6 0 0 6 6 6 3 HeH/LEM domain Vicilin_N PF04702.12 EAU87641.2 - 0.1 12.5 4.5 0.2 11.5 4.5 1.4 1 0 0 1 1 1 0 Vicilin N terminal region VPS13_C PF16909.5 EAU87641.2 - 0.12 12.2 0.1 0.82 9.4 0.1 2.0 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal ApoO PF09769.9 EAU87641.2 - 1.9 8.5 6.3 5.5 7.0 0.3 4.2 3 1 1 4 4 4 0 Apolipoprotein O Pan3_PK PF18101.1 EAU87642.1 - 1.2e-62 209.9 0.2 1.9e-62 209.3 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EAU87642.1 - 0.00025 20.5 0.0 0.033 13.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87642.1 - 0.0005 19.4 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LSM PF01423.22 EAU87644.2 - 6.7e-21 73.8 0.1 8e-21 73.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain HEAT_EZ PF13513.6 EAU87645.1 - 2.6e-17 62.9 6.9 5.9e-11 42.6 0.0 7.4 7 2 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 EAU87645.1 - 4.4e-17 60.7 9.6 0.00018 21.5 0.0 9.6 12 0 0 12 12 10 4 HEAT repeat HEAT_2 PF13646.6 EAU87645.1 - 4.4e-12 46.2 8.3 0.0015 18.9 0.0 7.6 3 2 1 5 5 5 3 HEAT repeats IBN_N PF03810.19 EAU87645.1 - 2.6e-11 43.3 1.0 3.7e-09 36.4 0.3 4.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.23 EAU87645.1 - 1.7e-08 34.2 3.7 0.004 17.2 0.1 4.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EAU87645.1 - 0.00024 21.2 1.9 0.017 15.1 0.0 3.8 2 2 3 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EAU87645.1 - 0.00041 20.3 0.2 0.049 13.5 0.0 4.0 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) IFRD PF05004.13 EAU87645.1 - 0.0055 15.8 5.0 1.4 7.9 0.0 3.6 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 EAU87645.1 - 0.017 14.3 1.4 0.65 9.0 0.0 3.5 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal TIP120 PF08623.10 EAU87645.1 - 0.018 14.8 1.0 0.71 9.6 0.0 3.4 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) DRIM PF07539.12 EAU87645.1 - 0.17 10.2 2.2 0.81 7.9 0.0 3.0 4 1 0 4 4 4 0 Down-regulated in metastasis RIX1 PF08167.12 EAU87645.1 - 0.21 11.3 2.1 3.5 7.3 0.1 3.5 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis p450 PF00067.22 EAU87646.2 - 2.1e-60 204.8 0.0 2.8e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.20 EAU87647.1 - 1.3e-74 251.5 6.4 1.3e-74 251.5 6.4 2.7 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EAU87647.1 - 2.1e-05 23.5 0.1 4e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein SR-25 PF10500.9 EAU87647.1 - 0.0061 16.2 8.0 0.0061 16.2 8.0 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Phage_tail_APC PF16778.5 EAU87647.1 - 0.1 12.5 0.9 0.24 11.3 0.9 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Coilin_N PF15862.5 EAU87647.1 - 4.2 7.2 9.1 11 5.8 9.1 1.7 1 0 0 1 1 1 0 Coilin N-terminus Membr_traf_MHD PF10540.9 EAU87648.2 - 2.3e-23 83.0 0.1 2.1e-10 40.9 0.0 3.0 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EAU87648.2 - 2.3e-10 40.7 0.0 1.1e-09 38.5 0.0 2.1 2 0 0 2 2 2 1 C2 domain CitG PF01874.16 EAU87648.2 - 0.004 16.9 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase HTH_54 PF18607.1 EAU87648.2 - 0.011 15.8 0.1 1.9 8.6 0.0 3.3 3 0 0 3 3 3 0 ParA helix turn helix domain DUF3285 PF11688.8 EAU87649.2 - 2 8.4 5.5 2.1 8.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) zf-C2H2 PF00096.26 EAU87650.2 - 1.1e-34 116.9 59.9 8.8e-05 22.7 1.0 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU87650.2 - 1.3e-24 85.4 62.1 2.2e-07 31.0 1.0 10.6 12 0 0 12 12 12 6 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU87650.2 - 1.6e-14 53.3 57.6 0.094 13.6 0.8 9.3 9 0 0 9 9 9 7 C2H2-type zinc finger FOXP-CC PF16159.5 EAU87650.2 - 9.3e-09 35.8 28.7 3.2 8.5 0.1 9.3 8 1 2 10 10 9 4 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EAU87650.2 - 6.5e-07 29.5 3.7 3.4 8.1 0.1 6.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 EAU87650.2 - 4.7e-05 24.0 13.2 0.18 12.5 1.9 3.7 3 0 0 3 3 3 3 TRAF-type zinc finger FYDLN_acid PF09538.10 EAU87650.2 - 0.00024 21.7 4.3 0.004 17.8 0.4 3.7 3 0 0 3 3 3 1 Protein of unknown function (FYDLN_acid) zf-met PF12874.7 EAU87650.2 - 0.00087 19.6 17.1 4.5 7.8 0.4 7.8 9 0 0 9 9 9 2 Zinc-finger of C2H2 type CpXC PF14353.6 EAU87650.2 - 0.058 13.4 0.0 3.4 7.8 0.0 3.0 3 0 0 3 3 3 0 CpXC protein GAGA PF09237.11 EAU87650.2 - 0.27 11.1 12.1 3.2 7.7 0.7 5.3 5 0 0 5 5 5 0 GAGA factor zf-LYAR PF08790.11 EAU87650.2 - 0.77 9.7 12.3 17 5.5 0.1 5.0 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 EAU87650.2 - 3.9 7.3 28.5 4.7 7.1 0.1 8.1 9 0 0 9 9 9 0 C2H2-type zinc-finger domain Tropomyosin_1 PF12718.7 EAU87651.2 - 0.00023 21.3 22.1 0.00023 21.3 22.1 5.8 1 1 5 6 6 6 1 Tropomyosin like ZapB PF06005.12 EAU87651.2 - 0.0027 18.1 0.5 0.0027 18.1 0.5 9.2 3 1 2 5 5 5 1 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EAU87651.2 - 0.0057 16.7 14.3 0.0057 16.7 14.3 7.4 1 1 5 6 6 6 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EAU87651.2 - 0.0095 16.0 19.5 0.0095 16.0 19.5 5.9 1 1 3 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 kleA_kleC PF17383.2 EAU87651.2 - 0.017 15.4 1.4 0.017 15.4 1.4 5.6 3 3 3 7 7 7 0 Uncharacterized KorC regulated protein A DUF1664 PF07889.12 EAU87651.2 - 0.43 10.6 53.9 0.46 10.5 2.3 6.9 2 2 5 7 7 7 0 Protein of unknown function (DUF1664) AA_permease_N PF08403.10 EAU87651.2 - 0.91 9.1 5.2 0.75 9.3 0.1 3.2 3 0 0 3 3 3 0 Amino acid permease N-terminal HMMR_N PF15905.5 EAU87651.2 - 1 8.8 99.7 1.9 7.9 22.8 5.7 1 1 4 5 5 5 0 Hyaluronan mediated motility receptor N-terminal DUF2935 PF11155.8 EAU87651.2 - 5.5 7.3 8.3 65 3.9 1.1 4.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) FPP PF05911.11 EAU87651.2 - 6.6 4.8 85.0 5.5 5.0 12.0 3.6 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil AA_permease_2 PF13520.6 EAU87652.2 - 1.1e-63 215.5 44.3 1.4e-63 215.2 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAU87652.2 - 3.9e-14 52.1 40.2 1.1e-13 50.7 40.2 1.6 1 1 0 1 1 1 1 Amino acid permease Ldh_1_N PF00056.23 EAU87654.2 - 2.9e-47 160.3 0.1 5.5e-47 159.4 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EAU87654.2 - 1.3e-40 139.0 0.0 1.9e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EAU87654.2 - 0.0028 16.7 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Gp_dh_C PF02800.20 EAU87655.2 - 1.7e-69 232.4 0.0 2.7e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EAU87655.2 - 2.8e-39 133.5 0.3 6.3e-39 132.4 0.3 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EAU87655.2 - 0.0057 16.8 0.2 0.019 15.1 0.2 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DUF2804 PF10974.8 EAU87655.2 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) 2-Hacid_dh_C PF02826.19 EAU87655.2 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 EAU87656.1 - 4.3e-67 224.6 0.0 5.9e-67 224.2 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EAU87656.1 - 2e-17 63.4 0.0 4.1e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peptidase_S26 PF10502.9 EAU87656.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 BP28CT PF08146.12 EAU87657.2 - 1.8e-26 92.9 0.1 9.8e-26 90.5 0.0 2.4 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EAU87657.2 - 7.9e-16 58.4 1.4 7.9e-16 58.4 1.4 6.9 9 0 0 9 9 9 1 U3 small nucleolar RNA-associated protein 10 SPO22 PF08631.10 EAU87657.2 - 2.1 7.7 8.7 0.58 9.6 0.0 4.2 6 0 0 6 6 6 0 Meiosis protein SPO22/ZIP4 like zinc_ribbon_9 PF14369.6 EAU87660.2 - 0.31 11.3 3.1 0.33 11.3 0.6 2.3 3 0 0 3 3 3 0 zinc-ribbon RNA_pol_I_A49 PF06870.12 EAU87662.1 - 2e-109 366.0 3.2 2.3e-109 365.8 3.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SRI PF08236.11 EAU87663.2 - 7.3e-18 64.5 20.8 8.1e-18 64.4 11.5 3.2 2 0 0 2 2 2 2 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EAU87663.2 - 5.4e-17 62.7 0.2 5.4e-17 62.7 0.2 4.2 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EAU87663.2 - 3.2e-13 49.5 11.2 3.2e-13 49.5 11.2 2.0 2 0 0 2 2 2 1 AWS domain CHAT PF12770.7 EAU87665.2 - 5.6e-26 91.6 0.0 1.3e-25 90.5 0.0 1.6 1 0 0 1 1 1 1 CHAT domain UBA2_C PF16195.5 EAU87666.2 - 0.88 10.3 5.3 0.54 11.0 3.4 1.7 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus SlyX PF04102.12 EAU87670.2 - 0.13 12.9 1.1 0.48 11.1 1.1 2.0 1 0 0 1 1 1 0 SlyX zf-CCHC PF00098.23 EAU87670.2 - 0.2 11.8 3.2 0.11 12.6 1.2 1.6 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 EAU87670.2 - 1.7 9.1 4.1 1.2 9.5 1.6 1.9 1 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF5133 PF17196.4 EAU87677.2 - 0.012 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) Cauli_VI PF01693.16 EAU87678.1 - 0.00051 20.3 0.2 0.00078 19.7 0.2 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3295 PF11702.8 EAU87680.2 - 0.00079 18.9 0.2 0.0013 18.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) COesterase PF00135.28 EAU87681.1 - 2.9e-75 254.1 0.0 6.6e-68 229.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU87681.1 - 3.3e-07 30.4 0.0 9.5e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 EAU87681.1 - 0.0052 16.3 0.1 0.0084 15.6 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EAU87681.1 - 0.014 16.0 0.3 0.014 16.0 0.3 2.4 2 1 1 3 3 3 0 Alpha/beta hydrolase family Esterase PF00756.20 EAU87681.1 - 0.05 13.2 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF348 PF03990.14 EAU87681.1 - 0.064 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Peptidase_S9 PF00326.21 EAU87681.1 - 0.094 12.2 0.1 0.25 10.8 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family UQ_con PF00179.26 EAU87683.2 - 3.2e-18 65.7 0.0 5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EBP50_C PF09007.11 EAU87683.2 - 0.21 12.6 6.1 0.066 14.2 3.1 1.7 2 0 0 2 2 2 0 EBP50, C-terminal PEMT PF04191.13 EAU87684.1 - 2.6e-32 111.3 2.9 5.3e-32 110.4 2.4 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase Glyco_hydro_3_C PF01915.22 EAU87685.2 - 1.4e-49 168.8 0.0 2.3e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAU87685.2 - 3.5e-34 118.6 0.0 5.3e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAU87685.2 - 1.7e-16 60.1 0.0 3.2e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 EAU87688.2 - 9.7e-47 159.6 0.0 1.8e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAU87688.2 - 6.1e-36 124.4 0.0 9.2e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAU87688.2 - 6.4e-20 71.0 0.0 1.3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain SKN1 PF03935.15 EAU87689.2 - 1.5e-174 581.1 7.5 1.7e-173 577.6 7.5 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 EAU87690.2 - 3.6e-172 573.2 2.8 4.6e-172 572.9 2.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GMC_oxred_N PF00732.19 EAU87691.1 - 3.3e-60 204.0 0.0 4.1e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87691.1 - 6.5e-33 114.3 0.0 1.2e-32 113.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU87691.1 - 8.1e-06 26.0 0.1 6.5e-05 23.1 0.2 2.6 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU87691.1 - 4.1e-05 22.8 0.1 0.0017 17.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain DUF723 PF05265.13 EAU87691.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF723) Lycopene_cycl PF05834.12 EAU87691.1 - 0.00067 18.8 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EAU87691.1 - 0.00098 18.4 0.0 0.0044 16.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU87691.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAU87691.1 - 0.0015 18.2 0.4 0.0032 17.1 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAU87691.1 - 0.0042 16.4 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU87691.1 - 0.053 12.2 0.1 0.1 11.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Glu_dehyd_C PF16912.5 EAU87691.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Rtt106 PF08512.12 EAU87692.1 - 8.4e-20 71.0 0.0 1.7e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EAU87692.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain BUD22 PF09073.10 EAU87692.1 - 0.43 9.9 15.8 0.94 8.7 15.8 1.6 1 0 0 1 1 1 0 BUD22 TrkH PF02386.16 EAU87693.2 - 8.8e-61 205.9 0.5 5.6e-55 186.7 0.0 2.8 2 1 0 2 2 2 2 Cation transport protein Mito_carr PF00153.27 EAU87694.2 - 6.1e-64 212.0 4.3 2.7e-21 75.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAU87694.2 - 0.07 12.3 2.9 0.23 10.6 0.1 2.9 1 1 0 2 2 2 0 Gammaproteobacterial serine protease HEM4 PF02602.15 EAU87695.1 - 1.2e-32 113.1 0.0 1.5e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD MnmE_helical PF12631.7 EAU87695.1 - 0.1 12.8 0.1 0.28 11.3 0.1 1.6 1 1 1 2 2 2 0 MnmE helical domain MIS13 PF08202.11 EAU87696.1 - 0.063 12.5 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Lyase_1 PF00206.20 EAU87697.1 - 3.7e-23 82.4 0.0 5.3e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EAU87697.1 - 1.5e-19 70.3 0.0 5.2e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.6 EAU87697.1 - 0.11 12.9 0.1 0.32 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Histone PF00125.24 EAU87700.2 - 5.4e-14 52.7 0.0 7.2e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAU87700.2 - 1.5e-08 34.2 0.0 1.5e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAU87700.2 - 0.0027 18.0 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Integrase_H2C2 PF17921.1 EAU87701.2 - 2.5e-09 37.1 2.3 5.5e-09 36.0 2.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 EAU87701.2 - 0.0028 17.8 0.1 0.0058 16.8 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger KA1 PF02149.19 EAU87703.2 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase PF00069.25 EAU87704.2 - 5.2e-70 235.8 0.0 7.4e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87704.2 - 4.3e-38 131.1 0.0 6.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU87704.2 - 8e-07 28.6 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 EAU87704.2 - 5.6e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EAU87704.2 - 0.006 15.6 0.5 0.012 14.6 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EAU87704.2 - 0.013 15.1 0.1 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EAU87704.2 - 0.045 13.7 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.22 EAU87705.2 - 5.5e-53 180.3 0.0 1.2e-52 179.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SNase PF00565.17 EAU87708.2 - 1.4e-19 70.5 0.0 2e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Baculo_PEP_C PF04513.12 EAU87709.1 - 0.0041 17.2 1.0 0.0051 16.8 1.0 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AI-2E_transport PF01594.16 EAU87709.1 - 0.031 13.4 1.8 0.041 13.0 1.8 1.2 1 0 0 1 1 1 0 AI-2E family transporter Nop14 PF04147.12 EAU87709.1 - 0.19 9.9 0.2 0.21 9.8 0.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF883 PF05957.13 EAU87709.1 - 0.79 10.4 4.9 5 7.8 4.8 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Bunya_RdRp PF04196.12 EAU87709.1 - 0.94 7.8 4.6 1.1 7.6 4.6 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase YtxH PF12732.7 EAU87709.1 - 1.5 9.4 13.6 0.26 11.8 1.0 2.4 2 1 0 2 2 2 0 YtxH-like protein TcdA_TcdB_pore PF12920.7 EAU87709.1 - 2.2 6.4 15.5 2.5 6.3 15.5 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain zf-C2H2 PF00096.26 EAU87710.2 - 0.0046 17.3 2.7 2 9.0 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU87710.2 - 0.093 13.6 8.2 0.42 11.6 0.1 3.1 3 1 0 3 3 3 0 C2H2-type zinc finger zf-RING_7 PF02591.15 EAU87710.2 - 0.21 11.8 1.4 5.2 7.3 0.2 2.9 3 0 0 3 3 3 0 C4-type zinc ribbon domain FOXP-CC PF16159.5 EAU87710.2 - 0.41 11.3 5.0 2.4 8.9 1.8 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain SWIB PF02201.18 EAU87711.1 - 8.4e-24 83.3 0.0 1.9e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3557 PF12078.8 EAU87711.1 - 0.094 12.7 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Ras PF00071.22 EAU87712.2 - 6.4e-46 155.9 0.3 1.6e-45 154.6 0.3 1.7 1 0 0 1 1 1 1 Ras family BAR PF03114.18 EAU87712.2 - 8.6e-36 123.8 9.7 1.3e-35 123.2 9.7 1.2 1 0 0 1 1 1 1 BAR domain Roc PF08477.13 EAU87712.2 - 2.1e-16 60.2 0.0 5.5e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SH3_1 PF00018.28 EAU87712.2 - 5.8e-10 38.6 0.1 1.2e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU87712.2 - 2.4e-08 33.7 0.0 5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU87712.2 - 8e-08 31.9 0.1 1.8e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arf PF00025.21 EAU87712.2 - 8.9e-08 31.8 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family BAR_3 PF16746.5 EAU87712.2 - 2.3e-06 27.5 8.1 4.2e-06 26.7 8.1 1.3 1 0 0 1 1 1 1 BAR domain of APPL family RsgA_GTPase PF03193.16 EAU87712.2 - 3.3e-05 23.8 0.1 0.16 11.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 EAU87712.2 - 0.00038 20.5 2.2 0.024 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 EAU87712.2 - 0.00041 19.9 2.7 0.0008 19.0 0.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAU87712.2 - 0.00043 20.3 0.0 0.0013 18.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EAU87712.2 - 0.016 14.9 1.8 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EAU87712.2 - 0.059 13.3 4.7 0.12 12.2 0.1 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea FeoB_N PF02421.18 EAU87712.2 - 0.11 12.0 0.0 0.86 9.1 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B LicD PF04991.13 EAU87712.2 - 0.12 12.5 1.5 0.26 11.4 1.5 1.6 1 0 0 1 1 1 0 LicD family Sec34 PF04136.15 EAU87712.2 - 0.13 12.2 6.5 0.26 11.2 6.5 1.5 1 0 0 1 1 1 0 Sec34-like family DUF2203 PF09969.9 EAU87712.2 - 0.38 11.5 8.4 1.8 9.3 4.3 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 EAU87712.2 - 1 7.9 6.8 2.3 6.7 6.8 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tho2 PF11262.8 EAU87712.2 - 1.9 7.6 7.6 3.3 6.8 7.6 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Dynamin_N PF00350.23 EAU87712.2 - 2.2 8.3 8.0 0.97 9.5 0.0 3.2 3 0 0 3 3 3 0 Dynamin family Fib_alpha PF08702.10 EAU87712.2 - 4 7.6 7.0 8.6 6.5 7.0 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EAU87712.2 - 4.1 5.2 6.5 6.5 4.5 6.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 EAU87712.2 - 4.6 7.6 16.1 0.42 10.9 11.0 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EAU87712.2 - 6.3 6.1 6.4 12 5.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OEP PF02321.18 EAU87712.2 - 7.5 6.3 9.9 14 5.4 9.9 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein P16-Arc PF04699.14 EAU87713.1 - 2.6e-52 177.3 0.0 2.9e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2711 PF10924.8 EAU87713.1 - 0.0076 15.9 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2711) Utp12 PF04003.12 EAU87713.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family p450 PF00067.22 EAU87714.2 - 2.6e-44 151.7 0.0 1.2e-28 100.1 0.1 2.9 2 1 0 2 2 2 2 Cytochrome P450 WD40 PF00400.32 EAU87715.2 - 0.26 12.2 5.3 1.5 9.8 0.7 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Afi1 PF07792.12 EAU87718.2 - 0.24 11.9 2.3 0.2 12.1 0.6 1.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PseudoU_synth_2 PF00849.22 EAU87719.2 - 4.2e-29 101.7 0.0 5.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase SNF2_N PF00176.23 EAU87720.1 - 1.5e-56 191.7 0.2 2.4e-56 190.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU87720.1 - 4.7e-17 62.3 0.0 1.3e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU87720.1 - 1.2e-06 28.7 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EAU87720.1 - 4.1e-06 26.6 3.9 2.5e-05 24.0 3.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU87720.1 - 9.6e-05 22.3 1.2 0.00024 21.0 1.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain SWI2_SNF2 PF18766.1 EAU87720.1 - 0.00038 20.2 0.0 0.00062 19.5 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-C3HC4_2 PF13923.6 EAU87720.1 - 0.00046 20.0 1.6 0.00046 20.0 1.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU87720.1 - 0.0032 17.7 5.0 0.0097 16.2 2.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU87720.1 - 0.0045 17.0 1.5 0.016 15.2 1.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAU87720.1 - 0.03 14.2 4.1 0.29 11.0 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 EAU87720.1 - 0.091 13.0 2.7 0.56 10.5 0.6 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Ada_Zn_binding PF02805.16 EAU87720.1 - 0.16 12.0 1.2 0.44 10.6 1.2 1.7 1 0 0 1 1 1 0 Metal binding domain of Ada Zn-C2H2_12 PF18112.1 EAU87720.1 - 0.22 12.0 1.5 1.5 9.4 0.0 2.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_4 PF15227.6 EAU87720.1 - 0.79 9.9 5.5 0.17 12.1 1.7 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EAU87720.1 - 2.3 8.2 7.1 51 3.8 4.9 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF1344 PF07076.11 EAU87721.1 - 0.61 10.0 1.9 1.2 9.1 0.7 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1344) Neisseria_TspB PF05616.13 EAU87723.1 - 0.011 14.2 2.3 0.012 14.1 2.3 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PT PF04886.12 EAU87723.1 - 0.5 9.9 9.3 12 5.6 9.3 3.0 1 1 0 1 1 1 0 PT repeat SKN1 PF03935.15 EAU87725.2 - 2.1e-177 590.5 0.1 2.4e-177 590.3 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 EAU87726.2 - 4.6e-180 599.3 0.0 5.3e-180 599.1 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) RrnaAD PF00398.20 EAU87730.2 - 1.1e-59 201.7 0.0 1.9e-59 200.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EAU87730.2 - 3.5e-06 27.6 0.0 7.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU87730.2 - 9.2e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAU87730.2 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EAU87730.2 - 0.00092 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EAU87730.2 - 0.0011 19.6 0.0 0.0024 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EAU87730.2 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EAU87730.2 - 0.0018 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EAU87730.2 - 0.0046 17.7 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU87730.2 - 0.021 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 EAU87730.2 - 0.058 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_28 PF02636.17 EAU87730.2 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 EAU87730.2 - 0.077 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.12 EAU87730.2 - 0.089 11.9 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase ATP-synt_ab PF00006.25 EAU87732.2 - 0.0049 16.5 0.1 0.0075 15.9 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain SUR7 PF06687.12 EAU87733.1 - 4e-05 23.4 6.6 0.00033 20.3 6.7 2.3 1 1 0 1 1 1 1 SUR7/PalI family DUF4915 PF16261.5 EAU87733.1 - 0.033 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) Phage_holin_3_6 PF07332.11 EAU87733.1 - 0.21 11.6 11.0 0.079 13.0 4.1 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4381 PF14316.6 EAU87733.1 - 0.46 10.7 0.0 0.46 10.7 0.0 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4381) Pkinase PF00069.25 EAU87734.2 - 3.6e-05 23.3 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Spo7_2_N PF15407.6 EAU87734.2 - 0.048 13.3 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 AAA_18 PF13238.6 EAU87738.2 - 3.7e-05 24.3 0.0 6.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAU87738.2 - 0.0012 19.1 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 EAU87738.2 - 0.0016 18.6 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 EAU87738.2 - 0.0019 18.4 0.0 0.0052 17.0 0.0 1.6 1 1 1 2 2 2 1 AAA domain G-alpha PF00503.20 EAU87738.2 - 0.0029 16.8 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_16 PF13191.6 EAU87738.2 - 0.0041 17.5 0.0 0.0072 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EAU87738.2 - 0.0044 17.0 0.0 0.0059 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EAU87738.2 - 0.0045 16.4 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.17 EAU87738.2 - 0.0051 16.9 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_24 PF13479.6 EAU87738.2 - 0.0054 16.5 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EAU87738.2 - 0.014 15.9 0.0 0.042 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAU87738.2 - 0.016 15.6 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EAU87738.2 - 0.024 14.4 0.1 0.057 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAU87738.2 - 0.026 15.1 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 EAU87738.2 - 0.03 14.3 0.0 0.074 13.0 0.0 1.6 1 1 1 2 2 2 0 NACHT domain PRK PF00485.18 EAU87738.2 - 0.031 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 EAU87738.2 - 0.043 13.5 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 EAU87738.2 - 0.064 13.5 0.0 0.091 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EAU87738.2 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 EAU87738.2 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EAU87738.2 - 0.25 10.8 0.0 0.38 10.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region OTT_1508_deam PF14441.6 EAU87739.1 - 8.3e-09 35.3 0.2 1.8e-08 34.2 0.2 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF3685 PF12452.8 EAU87739.1 - 0.17 11.5 0.3 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) PseudoU_synth_1 PF01416.20 EAU87740.1 - 9e-26 90.5 0.0 1.5e-24 86.5 0.0 2.7 2 1 0 2 2 2 1 tRNA pseudouridine synthase Lon_C PF05362.13 EAU87743.2 - 2.5e-59 200.3 2.5 2.2e-58 197.2 2.5 2.1 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EAU87743.2 - 4.8e-22 78.8 0.0 1.2e-21 77.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAU87743.2 - 1.3e-09 38.2 0.0 3.6e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 EAU87743.2 - 5e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 EAU87743.2 - 4.7e-05 23.2 0.2 0.00015 21.6 0.1 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EAU87743.2 - 0.00014 22.2 6.5 0.0022 18.4 0.1 3.7 2 2 1 4 4 4 1 AAA ATPase domain AAA_2 PF07724.14 EAU87743.2 - 0.0012 19.0 0.0 0.0046 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EAU87743.2 - 0.0023 18.2 1.3 0.34 11.2 0.1 3.6 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EAU87743.2 - 0.0039 16.9 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EAU87743.2 - 0.0053 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAU87743.2 - 0.0091 16.5 0.1 0.12 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EAU87743.2 - 0.025 14.4 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EAU87743.2 - 0.026 13.7 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain SKI PF01202.22 EAU87743.2 - 0.081 13.0 0.0 0.39 10.8 0.0 2.2 1 0 0 1 1 1 0 Shikimate kinase IstB_IS21 PF01695.17 EAU87743.2 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EAU87743.2 - 0.17 12.3 0.0 0.84 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase F-box-like PF12937.7 EAU87745.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Adaptin_N PF01602.20 EAU87746.1 - 8.5e-141 470.1 9.4 1.1e-140 469.7 9.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAU87746.1 - 9.1e-61 204.6 4.9 1.8e-59 200.4 0.9 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAU87746.1 - 2.2e-16 60.0 6.6 1.8e-06 28.2 0.0 6.2 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 EAU87746.1 - 8.1e-09 35.0 7.7 0.00014 21.8 0.1 6.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EAU87746.1 - 0.00013 22.4 2.4 1.9 9.1 0.1 5.7 5 1 1 6 6 6 1 HEAT-like repeat CLASP_N PF12348.8 EAU87746.1 - 0.0011 18.6 0.1 0.33 10.5 0.0 3.2 3 1 0 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 EAU87746.1 - 0.0012 19.0 0.6 0.6 10.3 0.0 3.8 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EAU87746.1 - 0.0027 17.7 5.1 4 7.6 0.0 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 EAU87746.1 - 0.064 13.2 1.6 0.33 10.8 0.2 2.8 1 1 2 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Nucleoporin_FG PF13634.6 EAU87746.1 - 0.081 13.8 7.5 0.22 12.4 7.5 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region DUF3678 PF12435.8 EAU87746.1 - 4.6 6.7 7.0 1.1 8.7 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Glyco_hydro_30 PF02055.16 EAU87747.2 - 2.1e-17 63.1 0.0 3.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAU87747.2 - 3.8e-06 26.4 0.0 6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 p450 PF00067.22 EAU87749.2 - 1.4e-66 225.2 0.0 1.7e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1289 PF06945.13 EAU87750.1 - 0.023 14.5 0.3 0.042 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) IATP PF04568.12 EAU87751.2 - 3.1e-10 40.4 3.6 3.2e-10 40.3 3.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF4140 PF13600.6 EAU87751.2 - 0.012 16.0 2.2 0.013 15.9 2.2 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 EAU87751.2 - 0.75 9.6 6.4 1.1 9.1 6.3 1.4 1 1 0 1 1 1 0 Septum formation initiator ATP_sub_h PF10775.9 EAU87752.1 - 1.6e-26 92.1 0.5 2.5e-26 91.5 0.5 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h RNA_pol PF00940.19 EAU87753.2 - 1.1e-179 597.6 0.0 1.5e-179 597.2 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EAU87753.2 - 1.9e-95 320.1 3.0 1.9e-95 320.1 3.0 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 EAU87753.2 - 0.00019 21.5 0.0 0.00042 20.4 0.0 1.6 1 0 0 1 1 1 1 PPR repeat family BCS1_N PF08740.11 EAU87757.2 - 6.3e-35 120.9 0.3 1.2e-34 119.9 0.3 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EAU87757.2 - 4.8e-18 65.9 0.0 1.1e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EAU87757.2 - 0.011 15.5 0.0 0.043 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAU87757.2 - 0.016 15.6 0.0 0.054 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EAU87757.2 - 0.016 15.6 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EAU87757.2 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 EAU87757.2 - 0.055 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EAU87757.2 - 0.091 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 EAU87757.2 - 0.095 12.7 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAU87757.2 - 0.12 13.0 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAU87757.2 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EAU87757.2 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) BCS1_N PF08740.11 EAU87758.2 - 1.7e-30 106.4 5.9 6.1e-30 104.6 0.4 2.3 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EAU87758.2 - 1.3e-21 77.4 0.0 2.8e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EAU87758.2 - 3.7e-05 23.7 5.5 0.0056 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU87758.2 - 0.0074 16.7 0.2 0.023 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ATPase PF06745.13 EAU87758.2 - 0.023 14.1 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 EAU87758.2 - 0.026 14.3 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EAU87758.2 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAU87758.2 - 0.16 11.7 0.2 0.16 11.7 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EAU87758.2 - 0.19 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Vfa1 PF08432.10 EAU87758.2 - 4.7 7.5 17.3 7.3 6.9 17.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 EAU87758.2 - 7.8 6.2 11.3 15 5.3 11.3 1.4 1 0 0 1 1 1 0 FAM176 family NARP1 PF12569.8 EAU87758.2 - 9.5 5.0 15.5 14 4.5 15.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 F-box-like PF12937.7 EAU87759.2 - 0.0033 17.3 0.0 0.55 10.2 0.0 3.0 2 1 0 2 2 2 2 F-box-like adh_short_C2 PF13561.6 EAU87762.2 - 2.7e-41 141.6 0.8 3.2e-41 141.4 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU87762.2 - 3.5e-36 124.5 0.2 4.4e-36 124.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU87762.2 - 8.3e-10 38.9 0.3 2.4e-09 37.4 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU87762.2 - 5.4e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAU87762.2 - 5.7e-05 23.1 0.3 0.00035 20.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EAU87762.2 - 0.00034 20.2 0.2 0.00067 19.3 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EAU87762.2 - 0.00074 18.7 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EAU87762.2 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EAU87762.2 - 0.0072 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EAU87762.2 - 0.061 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family STALD PF18185.1 EAU87762.2 - 0.061 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family RRM_1 PF00076.22 EAU87764.1 - 5.4e-14 51.8 0.2 4.4e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAU87764.1 - 0.04 13.9 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ABC1 PF03109.16 EAU87768.2 - 1.9e-23 82.9 0.0 1.4e-22 80.1 0.0 2.3 2 0 0 2 2 2 1 ABC1 family PRCC PF10253.9 EAU87768.2 - 0.0081 17.0 10.8 0.44 11.3 2.2 2.8 2 1 0 2 2 2 2 Mitotic checkpoint regulator, MAD2B-interacting DUF3533 PF12051.8 EAU87768.2 - 0.084 11.8 0.9 0.15 10.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) KDZ PF18758.1 EAU87769.2 - 4.2e-47 160.6 1.4 5.4e-47 160.3 0.1 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 EAU87769.2 - 2.8e-09 37.1 0.0 5.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 EAU87769.2 - 9.4e-09 35.4 0.1 5.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU87769.2 - 5.1e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases GcpE PF04551.14 EAU87769.2 - 0.11 11.6 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 GcpE protein End3 PF12761.7 EAU87769.2 - 0.4 10.8 3.5 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 OmpH PF03938.14 EAU87769.2 - 0.49 10.7 8.0 0.12 12.7 2.6 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EAU87769.2 - 0.91 8.8 7.0 1.7 7.9 3.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 EAU87769.2 - 2 8.9 6.2 32 5.1 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4378 PF14309.6 EAU87770.1 - 0.15 12.5 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Cucumo_coat PF00760.18 EAU87773.2 - 0.011 15.5 0.0 0.014 15.1 0.0 1.3 1 1 0 1 1 1 0 Cucumovirus coat protein eIF3g PF12353.8 EAU87775.2 - 0.0074 16.7 0.2 0.019 15.4 0.2 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 EAU87775.2 - 0.31 11.2 3.2 0.15 12.2 1.2 1.6 2 0 0 2 2 2 0 Zinc knuckle SlyX PF04102.12 EAU87775.2 - 0.71 10.5 3.5 0.7 10.6 1.1 2.3 2 0 0 2 2 2 0 SlyX SUIM_assoc PF16619.5 EAU87782.2 - 0.0052 16.8 0.6 0.0052 16.8 0.6 2.4 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 gpW PF02831.15 EAU87782.2 - 0.037 13.9 2.1 0.077 12.9 0.0 2.6 3 0 0 3 3 3 0 gpW Imm43 PF15570.6 EAU87782.2 - 0.049 13.6 0.7 2.8 8.0 0.2 2.3 2 0 0 2 2 2 0 Immunity protein 43 DUF2408 PF10303.9 EAU87782.2 - 0.055 14.0 10.3 0.4 11.2 7.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) Ndr PF03096.14 EAU87782.2 - 0.06 12.0 3.0 0.063 12.0 1.8 1.5 2 0 0 2 2 2 0 Ndr family DUF334 PF03904.13 EAU87782.2 - 0.19 11.2 6.9 0.33 10.4 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) LicD PF04991.13 EAU87782.2 - 0.3 11.2 2.8 17 5.5 2.1 2.3 2 0 0 2 2 2 0 LicD family COG5 PF10392.9 EAU87782.2 - 2.1 8.6 11.5 2.4 8.3 2.4 2.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF3584 PF12128.8 EAU87782.2 - 8.4 3.8 27.5 0.57 7.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) NOZZLE PF08744.10 EAU87783.2 - 0.087 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE EF1_GNE PF00736.19 EAU87784.1 - 1.1e-32 112.1 1.7 1.1e-32 112.1 1.7 1.9 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EAU87784.1 - 1.6e-12 47.7 5.3 1.6e-12 47.7 5.3 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 EAU87784.1 - 0.0024 17.9 0.1 0.041 13.9 0.1 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU87784.1 - 0.061 13.5 1.0 0.35 11.1 0.0 2.6 3 1 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DCR PF14047.6 EAU87787.1 - 0.0049 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Dppa2/4 conserved region NUDIX PF00293.28 EAU87791.2 - 3.9e-09 36.6 0.0 1.5e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain ANAPC4_WD40 PF12894.7 EAU87793.2 - 2.1e-07 31.1 1.2 0.13 12.5 0.0 4.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU87793.2 - 0.02 15.7 7.4 6.5 7.8 0.0 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat eIF2A PF08662.11 EAU87793.2 - 0.047 13.6 0.3 35 4.2 0.0 3.7 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EAU87794.2 - 2e-08 34.8 1.9 9.7e-05 23.1 0.2 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU87794.2 - 2.3e-07 31.0 0.8 7.3e-06 26.2 0.4 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU87794.2 - 0.0019 17.2 0.0 0.23 10.4 0.1 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase_Tyr PF07714.17 EAU87796.2 - 4.7e-47 160.4 0.0 7.6e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU87796.2 - 2e-34 119.1 0.0 1.3e-23 83.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 EAU87796.2 - 0.0023 17.5 0.1 0.0052 16.4 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EAU87796.2 - 0.021 14.2 0.0 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF713 PF05218.14 EAU87796.2 - 0.051 13.3 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF713) PPR_2 PF13041.6 EAU87799.2 - 0.0078 16.4 0.0 0.26 11.5 0.0 3.2 4 0 0 4 4 4 1 PPR repeat family Cas_Csy4 PF09618.10 EAU87799.2 - 0.056 13.6 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) TPR_10 PF13374.6 EAU87800.2 - 2.6e-16 58.9 1.9 0.029 14.3 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAU87800.2 - 6.3e-10 39.2 7.5 0.051 13.9 0.2 6.7 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAU87800.2 - 8.5e-09 34.9 0.0 2.1 8.6 0.0 6.3 7 0 0 7 7 5 3 Tetratricopeptide repeat NACHT PF05729.12 EAU87800.2 - 3.6e-07 30.2 0.1 1.9e-06 27.9 0.0 2.3 2 1 0 2 2 1 1 NACHT domain AAA_16 PF13191.6 EAU87800.2 - 3.3e-06 27.6 0.7 2.4e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.6 EAU87800.2 - 4.8e-05 23.1 1.3 14 6.0 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU87800.2 - 6.4e-05 22.6 0.3 8.4 6.4 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU87800.2 - 6.7e-05 23.4 12.1 7.4 7.7 0.1 8.3 7 1 2 9 9 7 1 Tetratricopeptide repeat AAA_33 PF13671.6 EAU87800.2 - 0.00012 22.3 0.0 0.00029 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAU87800.2 - 0.002 18.4 0.0 0.009 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAU87800.2 - 0.0028 18.1 0.0 0.012 16.1 0.0 2.1 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TPR_5 PF12688.7 EAU87800.2 - 0.0029 17.8 0.5 0.55 10.5 0.0 3.3 2 0 0 2 2 2 1 Tetratrico peptide repeat NB-ARC PF00931.22 EAU87800.2 - 0.0037 16.5 0.0 0.008 15.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.6 EAU87800.2 - 0.0048 17.0 0.0 4.9 7.6 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat RNA_helicase PF00910.22 EAU87800.2 - 0.0056 17.0 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EAU87800.2 - 0.0058 16.6 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Urb2 PF10441.9 EAU87800.2 - 0.024 14.6 0.5 0.7 9.8 0.1 2.5 2 0 0 2 2 2 0 Urb2/Npa2 family TsaE PF02367.17 EAU87800.2 - 0.029 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TPR_16 PF13432.6 EAU87800.2 - 0.043 14.5 8.5 4.6 8.0 0.0 5.7 4 2 2 6 6 5 0 Tetratricopeptide repeat AAA_5 PF07728.14 EAU87800.2 - 0.072 13.1 0.0 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PG_binding_1 PF01471.18 EAU87800.2 - 0.078 13.2 0.0 2 8.7 0.0 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain DUF4404 PF14357.6 EAU87800.2 - 2.9 8.6 7.1 31 5.3 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) Exonuc_VII_S PF02609.16 EAU87800.2 - 6.2 7.0 12.8 98 3.1 0.1 6.0 7 0 0 7 7 7 0 Exonuclease VII small subunit Terpene_synth_C PF03936.16 EAU87802.1 - 6.5e-06 25.7 0.0 8.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DrrA_P4M PF14860.6 EAU87802.1 - 0.097 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Aldo_ket_red PF00248.21 EAU87803.1 - 1.5e-53 182.0 0.0 1.7e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RINGv PF12906.7 EAU87804.1 - 3.9e-06 26.9 7.9 7.5e-06 26.0 7.9 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EAU87804.1 - 0.01 16.1 6.9 0.019 15.3 6.9 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 EAU87804.1 - 0.024 14.8 4.8 0.046 13.9 4.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EAU87804.1 - 0.099 12.7 0.9 0.24 11.5 0.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_5 PF13719.6 EAU87804.1 - 0.14 11.9 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4 PF00097.25 EAU87804.1 - 2.8 7.9 7.3 4.9 7.1 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU87804.1 - 3.6 7.9 7.2 7.4 7.0 7.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD_4 PF16866.5 EAU87804.1 - 7.7 6.7 8.9 16 5.7 8.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-primase PF09329.11 EAU87805.2 - 1.5e-16 59.9 5.0 2.8e-16 59.1 5.0 1.5 1 0 0 1 1 1 1 Primase zinc finger Snurportin1 PF11538.8 EAU87805.2 - 3 8.1 7.2 8.4 6.7 7.2 1.8 1 0 0 1 1 1 0 Snurportin1 ASF1_hist_chap PF04729.13 EAU87806.1 - 3.3e-65 218.8 0.0 3.8e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGEF PF00617.19 EAU87807.1 - 1e-32 113.8 0.1 3.7e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EAU87807.1 - 3.8e-10 39.9 0.5 1e-09 38.5 0.5 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif eIF2_C PF09173.11 EAU87810.1 - 1.9e-34 117.8 0.7 5.7e-34 116.2 0.7 1.9 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EAU87810.1 - 1.4e-21 77.0 2.1 2.3e-20 73.0 2.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EAU87810.1 - 1.7e-11 44.3 0.2 1.7e-11 44.3 0.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EAU87810.1 - 0.001 19.0 0.6 0.022 14.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EAU87810.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EAU87810.1 - 0.024 14.7 1.5 0.048 13.7 0.2 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain SIR2 PF02146.17 EAU87811.1 - 2e-27 96.2 0.0 1.5e-25 90.1 0.0 2.8 1 1 0 1 1 1 1 Sir2 family CBM_1 PF00734.18 EAU87811.1 - 0.37 10.8 3.3 6.5 6.8 0.7 2.6 2 0 0 2 2 2 0 Fungal cellulose binding domain p450 PF00067.22 EAU87812.2 - 1.9e-66 224.7 0.0 8.6e-62 209.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 PP28 PF10252.9 EAU87813.2 - 5e-26 91.0 16.7 5e-26 91.0 16.7 2.7 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Complex1_LYR PF05347.15 EAU87814.1 - 5.8e-10 39.1 0.7 9.5e-10 38.4 0.7 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EAU87814.1 - 0.00015 22.4 0.2 0.0002 22.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like F-box-like PF12937.7 EAU87817.1 - 1.7e-08 34.2 1.8 5.6e-08 32.6 1.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU87817.1 - 0.00062 19.6 3.0 0.0019 18.0 3.0 1.9 1 0 0 1 1 1 1 F-box domain CcmD PF04995.14 EAU87820.1 - 0.072 13.2 0.4 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) BatA PF07584.11 EAU87820.1 - 0.13 12.6 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal ArsR PF09824.9 EAU87820.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator Fes1 PF08609.10 EAU87822.1 - 3.7e-26 91.8 2.2 1.9e-25 89.6 2.5 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 EAU87822.1 - 0.00043 20.6 0.6 0.0052 17.2 0.1 2.8 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 EAU87822.1 - 0.0019 18.3 0.2 0.17 12.2 0.1 3.2 3 0 0 3 3 3 1 HEAT repeat TAN PF11640.8 EAU87822.1 - 0.0055 16.8 0.5 0.26 11.4 0.0 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 EAU87822.1 - 0.0076 16.7 0.3 0.95 10.0 0.1 2.9 1 1 2 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 EAU87822.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 EAU87822.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Glyco_hydro_115 PF15979.5 EAU87823.2 - 3.4e-138 460.7 0.8 6e-138 459.9 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EAU87823.2 - 1.4e-54 184.5 0.0 2.8e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 EAU87823.2 - 0.032 14.5 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus 60KD_IMP PF02096.20 EAU87824.1 - 2e-21 76.6 0.5 3.1e-21 76.0 0.5 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein EMC3_TMCO1 PF01956.16 EAU87824.1 - 0.014 15.1 0.8 0.028 14.2 0.1 1.9 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PIEZO PF15917.5 EAU87825.1 - 0.48 9.9 11.5 0.94 8.9 11.5 1.4 1 0 0 1 1 1 0 Piezo Atg14 PF10186.9 EAU87825.1 - 6.7 5.7 11.6 9.1 5.3 11.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DAZAP2 PF11029.8 EAU87826.1 - 0.03 15.2 1.4 0.042 14.8 1.1 1.4 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) FAM199X PF15814.5 EAU87827.1 - 9.7 5.1 17.7 6.3 5.8 13.7 2.5 2 0 0 2 2 2 0 Protein family FAM199X F-box-like PF12937.7 EAU87834.2 - 0.046 13.6 0.2 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EAU87834.2 - 0.77 9.7 5.2 14 5.7 0.1 4.0 4 0 0 4 4 4 0 F-box domain Ferritin_2 PF13668.6 EAU87835.1 - 1e-24 87.3 0.1 1.5e-24 86.8 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.6 EAU87836.1 - 8.4e-34 116.7 0.1 1.1e-33 116.3 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain ICMT PF04140.14 EAU87837.2 - 3.3e-11 43.5 0.2 3.3e-11 43.5 0.2 2.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAU87837.2 - 5e-09 36.5 0.3 7.4e-08 32.7 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EAU87837.2 - 0.0003 19.7 0.5 0.00043 19.2 0.2 1.4 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3955 PF13127.6 EAU87837.2 - 1.8 8.4 5.0 0.36 10.7 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) MFS_1 PF07690.16 EAU87838.2 - 1e-21 77.2 36.9 1.1e-14 54.1 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU87838.2 - 2e-18 66.5 13.6 7.9e-14 51.4 1.0 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter GST_N_3 PF13417.6 EAU87839.1 - 3.7e-09 36.9 0.1 3.5e-08 33.7 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU87839.1 - 5.5e-07 29.8 0.0 9.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU87839.1 - 1.4e-05 25.2 0.0 2.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU87839.1 - 0.00025 21.2 0.0 0.0012 19.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU87839.1 - 0.0026 17.8 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EAU87839.1 - 0.045 14.3 0.0 0.074 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF223 PF02721.14 EAU87845.2 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF223 DUF4050 PF13259.6 EAU87846.2 - 0.05 13.9 0.5 0.076 13.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PI31_Prot_C PF08577.11 EAU87849.2 - 0.14 13.3 3.4 0.43 11.8 3.4 2.1 1 1 0 1 1 1 0 PI31 proteasome regulator DLH PF01738.18 EAU87852.2 - 3.6e-17 62.6 0.0 4.4e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family GRP PF07172.11 EAU87852.2 - 0.005 17.5 11.9 0.0089 16.7 11.9 1.4 1 0 0 1 1 1 1 Glycine rich protein family CoA_trans PF01144.23 EAU87853.1 - 0.048 13.0 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Coenzyme A transferase LSM PF01423.22 EAU87855.2 - 1.5e-16 59.8 0.3 1.7e-16 59.6 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAU87855.2 - 0.00086 19.4 0.1 0.0011 19.1 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Peptidase_M43 PF05572.13 EAU87856.2 - 4.4e-17 62.4 0.0 6.4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EAU87856.2 - 0.00034 21.1 0.0 0.00082 19.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EAU87856.2 - 0.00034 20.8 0.2 0.00056 20.1 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAU87856.2 - 0.0046 16.6 0.2 0.0073 16.0 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87856.2 - 0.024 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 EAU87856.2 - 0.11 11.6 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_2 PF13574.6 EAU87856.2 - 0.17 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1996 PF09362.10 EAU87857.2 - 1.9e-70 237.5 0.5 2.6e-70 237.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU87857.2 - 1.4e-11 44.1 12.5 1.4e-11 44.1 12.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Prim-Pol PF09250.11 EAU87857.2 - 0.052 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Hydrophobin PF01185.18 EAU87858.1 - 2.1e-23 82.8 5.6 2.5e-23 82.5 5.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ras PF00071.22 EAU87860.2 - 1.6e-05 24.6 0.0 0.00015 21.4 0.0 2.4 2 1 0 2 2 2 1 Ras family Peptidase_C14 PF00656.22 EAU87861.2 - 1.1e-32 114.0 0.0 1.6e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Glyco_hydro_28 PF00295.17 EAU87862.2 - 3.9e-44 151.0 12.6 5.1e-44 150.6 12.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CLCA PF08434.11 EAU87863.2 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal CLCA PF08434.11 EAU87864.1 - 0.058 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel N terminal DLH PF01738.18 EAU87866.1 - 8.1e-17 61.5 0.0 9.8e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EAU87866.1 - 0.032 13.9 0.0 0.76 9.4 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Pheromone PF08015.11 EAU87868.2 - 0.031 15.3 0.7 0.047 14.7 0.7 1.5 1 1 0 1 1 1 0 Fungal mating-type pheromone Glyco_hydro_59 PF02057.15 EAU87869.2 - 9.2e-14 51.4 0.1 1.3e-13 50.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAU87869.2 - 9.5e-08 32.0 3.5 4.4e-05 23.2 0.1 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 EAU87869.2 - 2.4e-07 30.9 10.3 7.7e-07 29.2 9.2 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EAU87869.2 - 3.9e-06 26.1 0.0 6.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain SnoaL_2 PF12680.7 EAU87870.1 - 0.0036 17.9 1.7 0.0051 17.4 1.7 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EAU87870.1 - 0.0081 16.0 0.7 0.084 12.7 0.7 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SKG6 PF08693.10 EAU87871.2 - 5.1 6.6 7.5 13 5.3 7.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UCR_hinge PF02320.16 EAU87873.2 - 1.8e-12 47.3 3.9 3.3e-12 46.4 3.9 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Bindin PF02084.15 EAU87873.2 - 0.69 10.1 1.9 1 9.6 1.9 1.2 1 0 0 1 1 1 0 Bindin DLH PF01738.18 EAU87874.2 - 1.2e-16 60.9 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Ricin_B_lectin PF00652.22 EAU87875.1 - 1.5e-24 86.6 0.1 1.9e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU87875.1 - 1.8e-16 60.6 0.5 1.5e-07 32.0 0.5 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SnoaL_2 PF12680.7 EAU87876.1 - 0.00015 22.4 0.3 0.00021 21.9 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EAU87876.1 - 0.027 14.2 0.1 0.17 11.7 0.1 2.0 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase PMSR PF01625.21 EAU87877.1 - 4.7e-62 208.7 0.4 5.8e-62 208.4 0.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TAL_FSA PF00923.19 EAU87878.1 - 1.3e-55 188.8 0.0 5.4e-52 176.9 0.0 2.4 2 1 0 2 2 2 2 Transaldolase/Fructose-6-phosphate aldolase VapB_antitoxin PF09957.9 EAU87878.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB Baculo_PEP_C PF04513.12 EAU87881.1 - 0.0053 16.8 0.4 0.0053 16.8 0.4 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_38N PF01074.22 EAU87883.2 - 1.4e-79 267.5 0.2 2.1e-79 266.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EAU87883.2 - 1.5e-48 165.7 0.0 2.3e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EAU87883.2 - 1.8e-13 50.4 0.1 4.8e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EAU87883.2 - 4e-05 23.6 0.0 0.00013 22.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EAU87883.2 - 0.03 13.5 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Thymidylat_synt PF00303.19 EAU87885.1 - 2.9e-107 357.8 0.0 3.3e-107 357.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase NAD_binding_4 PF07993.12 EAU87887.2 - 9e-31 107.0 0.0 1.8e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EAU87887.2 - 5.8e-09 35.8 0.0 1.7e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 EAU87887.2 - 1.5e-05 23.8 0.2 5.2e-05 22.0 0.0 1.9 2 1 0 2 2 2 1 AMP-binding enzyme 3Beta_HSD PF01073.19 EAU87887.2 - 0.12 11.4 0.0 1.5 7.8 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAU87887.2 - 0.23 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF2062 PF09835.9 EAU87889.2 - 0.045 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) CE2_N PF17996.1 EAU87889.2 - 0.19 11.7 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal GMC_oxred_N PF00732.19 EAU87893.2 - 7.6e-62 209.3 0.0 9.6e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87893.2 - 2.8e-32 112.2 0.0 5e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU87893.2 - 2.7e-05 24.3 0.3 0.00014 22.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU87893.2 - 0.0032 17.1 0.6 0.01 15.4 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAU87893.2 - 0.0033 16.6 0.1 0.033 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EAU87893.2 - 0.0046 16.1 0.1 0.0068 15.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EAU87893.2 - 0.013 14.8 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EAU87893.2 - 0.046 12.9 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EAU87893.2 - 0.25 10.1 0.2 1.9 7.2 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 EAU87895.1 - 8.8e-65 219.0 0.0 1.1e-64 218.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87895.1 - 1.3e-33 116.5 0.0 2.6e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU87895.1 - 8.8e-06 25.9 0.1 0.00013 22.1 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU87895.1 - 0.00012 21.3 0.0 0.026 13.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EAU87895.1 - 0.00073 18.7 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EAU87895.1 - 0.00095 18.8 0.2 0.025 14.2 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EAU87895.1 - 0.03 14.6 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 EAU87895.1 - 0.038 13.2 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU87895.1 - 0.059 12.1 0.0 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EAU87895.1 - 0.093 11.6 0.9 0.36 9.6 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase Ntox37 PF15535.6 EAU87895.1 - 1.3 9.5 4.0 0.57 10.7 0.6 2.1 2 0 0 2 2 2 0 Bacterial toxin 37 Peptidase_M28 PF04389.17 EAU87896.1 - 5.3e-38 130.7 0.0 7.6e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAU87896.1 - 8.2e-15 54.6 0.4 2.1e-14 53.3 0.4 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EAU87896.1 - 0.00044 20.0 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 GMC_oxred_N PF00732.19 EAU87897.2 - 6.6e-61 206.3 0.0 9.5e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87897.2 - 2.8e-29 102.5 0.0 4.5e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU87897.2 - 0.00017 21.8 0.0 0.00044 20.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU87897.2 - 0.00068 18.8 0.1 0.001 18.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EAU87897.2 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EAU87897.2 - 0.014 14.5 0.0 0.058 12.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 EAU87897.2 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 EAU87897.2 - 0.025 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 EAU87898.1 - 8.6e-64 215.7 0.0 1.1e-63 215.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87898.1 - 9.4e-34 117.0 0.0 1.4e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU87898.1 - 0.01 16.0 0.1 0.059 13.6 0.0 2.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU87898.1 - 0.019 14.1 0.1 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EAU87898.1 - 0.019 14.1 0.1 0.032 13.3 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 EAU87899.2 - 8.6e-65 219.0 0.0 1.1e-64 218.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87899.2 - 4.2e-35 121.4 0.0 6.9e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAU87899.2 - 0.0065 15.6 0.1 0.58 9.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EAU87899.2 - 0.0067 15.5 0.1 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU87899.2 - 0.013 15.8 0.1 0.053 13.8 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UBN_AB PF14075.6 EAU87900.1 - 1.3e-42 145.9 0.0 1.3e-42 145.9 0.0 2.8 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 EAU87900.1 - 3.9e-13 49.2 0.3 3.9e-13 49.2 0.3 2.9 3 0 0 3 3 3 1 HPC2 and ubinuclein domain PI3K_1B_p101 PF10486.9 EAU87900.1 - 0.28 8.9 4.8 0.46 8.2 4.8 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GMC_oxred_N PF00732.19 EAU87901.2 - 3.6e-64 217.0 0.0 4.6e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU87901.2 - 1.1e-29 103.8 0.0 1.6e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EAU87901.2 - 0.00099 18.3 0.0 0.16 11.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EAU87901.2 - 0.0026 17.1 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EAU87901.2 - 0.012 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EAU87901.2 - 0.039 14.2 0.1 0.13 12.5 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Importin_rep PF18773.1 EAU87903.1 - 3.3e-11 42.7 0.0 7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 EAU87903.1 - 3e-08 33.8 0.2 4.2e-06 26.9 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein Importin_rep_3 PF18806.1 EAU87903.1 - 4.6e-06 26.6 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Importin 13 repeat CRM1_C PF08767.11 EAU87903.1 - 0.00089 18.5 0.0 0.0063 15.7 0.0 2.1 2 0 0 2 2 2 1 CRM1 C terminal Kdo PF06293.14 EAU87904.2 - 2e-05 24.0 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.14 EAU87904.2 - 0.00084 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase RIO1 PF01163.22 EAU87904.2 - 0.002 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAU87904.2 - 0.033 14.1 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HIT PF01230.23 EAU87904.2 - 0.075 13.8 0.3 0.87 10.4 0.0 2.3 2 0 0 2 2 2 0 HIT domain Choline_kinase PF01633.20 EAU87904.2 - 0.13 11.8 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 EAU87904.2 - 0.17 11.2 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain ACPS PF01648.20 EAU87907.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Peptidase_M16 PF00675.20 EAU87908.1 - 2.9e-21 76.0 0.1 5.8e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAU87908.1 - 0.011 15.8 0.0 0.048 13.7 0.0 2.1 1 1 0 1 1 1 0 Peptidase M16 inactive domain DUF383 PF04063.14 EAU87908.1 - 0.055 13.1 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) NST1 PF13945.6 EAU87909.2 - 3.9e-57 193.5 2.0 3.9e-57 193.5 2.0 5.6 3 2 3 6 6 6 1 Salt tolerance down-regulator Lipase_GDSL_2 PF13472.6 EAU87910.1 - 3.2e-14 53.7 1.5 4.8e-14 53.2 0.8 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU87910.1 - 6.7e-09 36.0 0.1 1.2e-08 35.2 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 EAU87910.1 - 0.0085 16.1 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_3 PF14606.6 EAU87910.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TMEM51 PF15345.6 EAU87914.2 - 0.091 12.6 0.8 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 Gram_pos_anchor PF00746.21 EAU87914.2 - 0.35 10.9 1.6 0.91 9.5 1.6 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif HEAT PF02985.22 EAU87915.2 - 1.5e-13 49.7 16.6 0.036 14.3 0.1 10.2 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 EAU87915.2 - 1.7e-13 50.8 20.4 0.0037 17.6 0.2 8.5 6 3 3 10 10 10 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EAU87915.2 - 9e-05 23.0 0.2 5.7 7.6 0.0 5.1 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 EAU87915.2 - 0.065 12.4 5.7 0.41 9.8 0.0 4.5 7 0 0 7 7 7 0 Nuclear condensing complex subunits, C-term domain IFRD PF05004.13 EAU87915.2 - 0.087 11.9 1.6 3.1 6.8 0.1 3.1 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) TIP120 PF08623.10 EAU87915.2 - 0.26 11.0 0.6 13 5.5 0.0 3.5 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 EAU87915.2 - 0.37 11.3 17.5 14 6.4 0.0 6.6 7 0 0 7 7 7 0 HEAT-like repeat HEAT_PBS PF03130.16 EAU87915.2 - 0.79 10.6 4.5 21 6.1 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Glyco_hydro_79C PF16862.5 EAU87916.1 - 4.4e-20 72.5 0.2 1.4e-19 70.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain F-box-like PF12937.7 EAU87917.2 - 0.0018 18.1 0.0 0.01 15.7 0.0 2.4 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU87917.2 - 0.07 13.6 1.5 40 4.8 0.0 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 EAU87918.2 - 7.3e-19 67.8 0.0 2.6e-17 62.7 0.0 2.2 1 1 1 2 2 2 2 Fungal protein kinase AMP-binding PF00501.28 EAU87919.1 - 1.1e-93 314.2 0.0 1.4e-93 313.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU87919.1 - 0.0058 17.6 0.0 0.015 16.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LRR_8 PF13855.6 EAU87920.2 - 0.00043 20.0 2.0 0.098 12.4 0.1 3.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EAU87920.2 - 0.031 14.7 0.2 2.2 8.8 0.1 3.7 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) AMP-binding PF00501.28 EAU87921.1 - 1.3e-93 313.9 0.0 1.8e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU87921.1 - 8.6e-05 23.4 0.6 0.00095 20.1 0.1 2.5 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain FAINT PF04385.15 EAU87921.1 - 0.066 13.3 0.6 0.14 12.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 DUF2104 PF09877.9 EAU87921.1 - 0.15 12.3 0.6 0.47 10.7 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) GATA PF00320.27 EAU87922.1 - 2.1e-25 88.0 19.5 4e-15 55.1 3.3 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 EAU87922.1 - 5.1e-11 42.2 0.3 1.1e-10 41.1 0.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Zn-ribbon_8 PF09723.10 EAU87922.1 - 0.022 14.9 5.4 2 8.6 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 EAU87922.1 - 0.17 11.8 6.2 4.7 7.1 0.4 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Auto_anti-p27 PF06677.12 EAU87922.1 - 0.17 12.1 5.9 0.73 10.0 0.9 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.12 EAU87922.1 - 0.45 10.1 7.2 0.49 10.0 0.8 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 EAU87922.1 - 0.66 10.3 2.9 1 9.7 0.8 2.4 3 0 0 3 3 3 0 zinc-ribbon zinc_ribbon_4 PF13717.6 EAU87922.1 - 1.5 8.8 4.8 2.4 8.1 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EAU87922.1 - 2 7.9 6.0 3.8 7.1 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EAU87922.1 - 2.2 8.4 9.7 25 5.0 9.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EAU87922.1 - 2.3 8.2 8.8 2.3 8.2 2.1 2.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Elf1 PF05129.13 EAU87922.1 - 5.8 7.0 7.0 2.4 8.2 0.3 2.8 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like AMP-binding PF00501.28 EAU87926.1 - 2e-25 89.3 0.0 2.6e-24 85.6 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 EAU87926.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Tyr-DNA_phospho PF06087.12 EAU87927.2 - 2.2e-64 217.9 0.0 3.2e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EAU87927.2 - 3.9e-05 23.3 11.6 6.7e-05 22.5 2.7 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif PLDc_2 PF13091.6 EAU87927.2 - 0.012 15.5 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain SPX PF03105.19 EAU87927.2 - 3.4 7.5 17.0 0.89 9.4 13.9 1.5 2 0 0 2 2 2 0 SPX domain NAD_binding_10 PF13460.6 EAU87928.2 - 5.2e-28 98.2 0.1 6.6e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAU87928.2 - 1.5e-05 24.6 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EAU87928.2 - 0.001 19.5 0.1 0.0018 18.7 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 EAU87928.2 - 0.048 13.7 0.3 0.092 12.8 0.3 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 EAU87928.2 - 0.067 12.7 0.3 0.1 12.2 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.12 EAU87928.2 - 0.081 12.1 0.0 0.21 10.7 0.0 1.7 1 1 1 2 2 2 0 Male sterility protein TrkA_N PF02254.18 EAU87928.2 - 0.086 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EAU87928.2 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EAU87928.2 - 0.15 12.5 0.2 0.27 11.7 0.2 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_62 PF03664.13 EAU87930.1 - 2.2e-62 210.9 2.4 2.7e-62 210.6 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 EAU87930.1 - 1.4e-13 50.5 5.7 1.4e-13 50.5 5.7 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain DEC-1_N PF04625.13 EAU87930.1 - 4.4 6.2 4.4 6.8 5.6 4.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_hydro_62 PF03664.13 EAU87931.2 - 2.9e-58 197.4 0.1 3.4e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Pkinase PF00069.25 EAU87932.2 - 2.4e-37 128.7 0.0 3e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU87932.2 - 1.5e-20 73.6 0.0 1.9e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M43 PF05572.13 EAU87934.1 - 2.7e-19 69.6 0.0 4.1e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87934.1 - 3e-07 30.8 0.0 5.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU87934.1 - 1.2e-05 25.8 0.0 1.8e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU87934.1 - 0.0095 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 EAU87934.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EAU87934.1 - 0.054 13.1 0.6 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 EAU87934.1 - 0.08 12.8 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EAU87934.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 EAU87934.1 - 0.32 9.9 3.4 0.48 9.3 3.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Trypan_PARP PF05887.11 EAU87934.1 - 4.8 7.2 27.5 2 8.4 24.8 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.22 EAU87935.2 - 4e-43 147.8 0.0 4.7e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU87936.1 - 5.2e-41 140.9 0.0 6.9e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU87937.1 - 2.8e-49 168.1 0.0 3.4e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU87938.2 - 4.5e-24 85.0 0.0 2.6e-21 75.9 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 HEAT_PBS PF03130.16 EAU87938.2 - 0.09 13.5 0.0 0.51 11.2 0.0 2.2 1 1 1 2 2 2 0 PBS lyase HEAT-like repeat Glyco_hydro_18 PF00704.28 EAU87939.1 - 6e-49 167.4 0.6 9e-49 166.9 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.24 EAU87939.1 - 5.1e-13 49.0 0.0 9.3e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 PX domain Glyco_hydro_114 PF03537.13 EAU87939.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Acetyltransf_9 PF13527.7 EAU87941.2 - 1.6e-05 25.0 0.3 0.0036 17.4 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU87941.2 - 0.0086 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU87941.2 - 0.025 14.8 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU87941.2 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAU87941.2 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 EAU87942.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EAU87942.1 - 0.025 14.7 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAU87942.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 EAU87942.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU87942.1 - 0.17 12.4 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_71 PF03659.14 EAU87943.2 - 1.3e-100 336.9 0.4 1.6e-100 336.6 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.19 EAU87943.2 - 7.5e-20 70.9 11.0 2.2e-14 53.4 7.9 2.3 2 0 0 2 2 2 2 WSC domain DUF3586 PF12131.8 EAU87943.2 - 1.3 9.3 9.2 4.8 7.5 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) La PF05383.17 EAU87944.1 - 1.5e-22 79.4 0.0 4.4e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EAU87944.1 - 7.8e-08 32.0 2.2 3.9e-07 29.8 0.5 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAU87944.1 - 1.1e-06 28.7 0.2 2.5e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif PhoLip_ATPase_C PF16212.5 EAU87947.2 - 1.6e-52 178.7 24.6 1.6e-52 178.7 24.6 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAU87947.2 - 8.9e-17 60.5 7.2 2.2e-16 59.3 7.2 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAU87947.2 - 2.3e-13 50.9 1.6 1e-07 32.5 0.7 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAU87947.2 - 7.1e-13 48.5 0.0 7.1e-13 48.5 0.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EAU87947.2 - 1.1e-09 38.3 0.0 1.5e-08 34.6 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU87947.2 - 0.00014 21.7 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Velvet PF11754.8 EAU87949.1 - 1.8e-58 198.5 0.1 1.9e-39 136.1 0.0 6.5 2 2 1 3 3 3 2 Velvet factor DNA_pol_lambd_f PF10391.9 EAU87950.2 - 3e-22 78.2 0.2 6.4e-22 77.1 0.2 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DPBB_1 PF03330.18 EAU87950.2 - 6.8e-09 35.9 0.0 1.7e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Lytic transglycolase DNA_pol_B_palm PF14792.6 EAU87950.2 - 5.6e-07 29.8 0.0 9.9e-06 25.7 0.0 2.4 1 1 1 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EAU87950.2 - 0.00016 21.7 0.1 0.0005 20.2 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_5 PF14520.6 EAU87950.2 - 0.071 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain LIG3_BRCT PF16759.5 EAU87950.2 - 0.16 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 EAU87950.2 - 0.17 12.3 0.0 0.5 10.8 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Methyltransf_31 PF13847.6 EAU87951.1 - 2.1e-13 50.3 0.0 8.3e-13 48.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU87951.1 - 2.2e-13 50.4 0.0 3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU87951.1 - 1.2e-12 48.4 0.0 3.3e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU87951.1 - 1.5e-10 41.6 0.0 2.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU87951.1 - 2e-06 28.4 0.0 4.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EAU87951.1 - 7.6e-06 25.5 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 EAU87951.1 - 8e-05 22.1 0.0 0.00054 19.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EAU87951.1 - 0.0027 17.8 0.0 0.0084 16.2 0.0 1.6 1 1 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 EAU87951.1 - 0.022 14.3 0.0 0.073 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_29 PF03141.16 EAU87951.1 - 0.076 11.5 0.0 0.093 11.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_17 PF12692.7 EAU87951.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase p450 PF00067.22 EAU87952.2 - 2.1e-43 148.8 0.0 2.7e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EphA2_TM PF14575.6 EAU87952.2 - 0.12 13.3 0.1 0.34 11.8 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ank_2 PF12796.7 EAU87956.2 - 1.9e-42 143.7 10.7 5.3e-13 49.4 0.4 3.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU87956.2 - 3.5e-24 84.5 6.3 5e-10 39.4 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EAU87956.2 - 8e-24 83.0 7.1 4.4e-05 23.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAU87956.2 - 7e-23 80.7 13.3 6.3e-06 26.6 0.1 5.4 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU87956.2 - 8.3e-21 71.9 8.4 0.00023 21.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat DHHC PF01529.20 EAU87956.2 - 5.5e-08 33.0 1.2 5.5e-08 33.0 1.2 3.4 2 1 1 3 3 3 2 DHHC palmitoyltransferase EF1G PF00647.19 EAU87957.1 - 1.4e-41 140.8 0.0 2.4e-41 140.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EAU87957.1 - 1.5e-11 44.5 0.0 3.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU87957.1 - 7.3e-11 42.1 0.0 2.1e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU87957.1 - 1e-08 35.3 0.0 5.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU87957.1 - 5.4e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EAU87957.1 - 0.0018 18.7 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EAU87957.1 - 0.025 14.4 0.0 0.085 12.7 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.19 EAU87957.1 - 0.057 14.0 5.5 0.19 12.4 5.5 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.7 EAU87958.2 - 2.4e-06 27.3 0.1 8.4e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU87958.2 - 0.00051 19.9 0.4 0.0031 17.4 0.4 2.4 1 1 0 1 1 1 1 F-box domain Peptidase_M43 PF05572.13 EAU87960.1 - 3.1e-18 66.1 0.5 6.6e-18 65.1 0.1 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU87960.1 - 0.00026 21.2 0.1 0.00041 20.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAU87960.1 - 0.0028 17.3 0.1 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EAU87960.1 - 0.0083 16.0 0.2 0.015 15.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EAU87960.1 - 0.019 15.5 0.5 0.035 14.6 0.5 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 EAU87960.1 - 0.054 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.24 EAU87960.1 - 0.06 13.2 0.3 0.094 12.6 0.3 1.5 1 1 0 1 1 1 0 Matrixin AAA PF00004.29 EAU87961.2 - 1.4e-20 74.1 0.0 2.2e-10 41.1 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EAU87961.2 - 5.3e-20 72.2 0.2 8.7e-14 51.9 0.1 2.6 1 1 1 2 2 2 2 BCS1 N terminal AAA_16 PF13191.6 EAU87961.2 - 0.001 19.5 0.2 0.0026 18.2 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 EAU87961.2 - 0.0012 18.7 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EAU87961.2 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EAU87961.2 - 0.017 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EAU87961.2 - 0.023 15.0 0.0 0.084 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EAU87961.2 - 0.028 14.4 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EAU87961.2 - 0.037 13.9 0.0 0.087 12.7 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_6 PF12774.7 EAU87961.2 - 0.042 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EAU87961.2 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EAU87961.2 - 0.051 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EAU87961.2 - 0.078 13.5 0.0 0.28 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EAU87961.2 - 0.081 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU87961.2 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAU87961.2 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.26 EAU87962.2 - 8.7e-28 96.9 0.2 1.3e-27 96.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU87962.2 - 3.8e-16 60.3 0.0 7.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU87962.2 - 7.7e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EAU87962.2 - 0.0031 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Cullin_binding PF03556.15 EAU87963.1 - 5e-37 127.0 0.0 8.8e-37 126.2 0.0 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EAU87963.1 - 6.2e-07 29.1 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain MPP6 PF10175.9 EAU87965.2 - 7.7e-08 32.9 0.3 7.7e-08 32.9 0.3 2.1 2 1 0 2 2 2 1 M-phase phosphoprotein 6 ADH_zinc_N PF00107.26 EAU87971.1 - 1.8e-29 102.3 0.3 3.3e-29 101.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU87971.1 - 1e-18 68.7 0.0 2.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU87971.1 - 1.1e-11 44.6 0.1 2.3e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EAU87971.1 - 0.037 13.3 0.1 0.058 12.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EAU87971.1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.22 EAU87972.2 - 1.4e-39 136.2 0.0 1.9e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU87973.1 - 1.9e-42 145.6 0.0 2.2e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU87974.2 - 7.5e-40 137.0 0.0 2e-39 135.6 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 Imm_superinfect PF14373.6 EAU87974.2 - 0.11 12.4 1.2 0.31 11.0 1.2 1.7 1 0 0 1 1 1 0 Superinfection immunity protein p450 PF00067.22 EAU87975.2 - 1.1e-44 153.0 0.0 1.3e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb5_C PF01191.19 EAU87975.2 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain NACHT PF05729.12 EAU87977.2 - 2.4e-10 40.6 0.0 3.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU87977.2 - 1.5e-06 28.7 0.0 3.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU87977.2 - 8e-05 22.9 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU87977.2 - 0.00047 19.9 0.0 0.00075 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EAU87977.2 - 0.0069 16.8 0.0 0.075 13.5 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EAU87977.2 - 0.039 13.5 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 EAU87977.2 - 0.086 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ATPase_2 PF01637.18 EAU87977.2 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EAU87977.2 - 0.14 12.1 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EAU87977.2 - 0.16 12.3 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Peptidase_S8 PF00082.22 EAU87978.1 - 2.4e-41 142.0 0.7 2.4e-41 142.0 0.7 1.5 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 EAU87978.1 - 1e-26 92.8 0.3 2.2e-26 91.7 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Sigma70_ner PF04546.13 EAU87978.1 - 0.1 12.5 7.9 0.25 11.2 7.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 EAU87978.1 - 0.32 10.3 10.1 0.48 9.7 10.1 1.3 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 EAU87978.1 - 0.53 9.8 9.6 0.92 9.0 9.6 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EAU87978.1 - 0.88 8.8 15.3 1.6 8.0 15.3 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EAU87978.1 - 0.89 7.7 12.8 1.3 7.2 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EAU87978.1 - 1.5 8.6 9.8 2.9 7.7 9.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sporozoite_P67 PF05642.11 EAU87978.1 - 1.5 6.8 9.7 2.4 6.1 9.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GEN1_C PF18380.1 EAU87978.1 - 1.6 9.7 8.2 6.1 7.8 8.2 2.0 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain FAM176 PF14851.6 EAU87978.1 - 1.6 8.4 10.2 3.4 7.3 10.2 1.5 1 0 0 1 1 1 0 FAM176 family CobT PF06213.12 EAU87978.1 - 3.1 7.1 13.4 5 6.4 13.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 EAU87978.1 - 3.7 5.5 20.1 5.5 5.0 20.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nucleo_P87 PF07267.11 EAU87978.1 - 9.9 4.9 5.6 15 4.3 5.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Methyltransf_11 PF08241.12 EAU87979.2 - 6.2e-16 58.8 0.0 1.2e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU87979.2 - 3.8e-14 53.2 0.0 1.2e-13 51.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU87979.2 - 2.8e-10 40.8 0.0 9.9e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU87979.2 - 1.3e-09 38.0 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU87979.2 - 2.9e-08 33.7 0.0 4.1e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAU87979.2 - 0.00034 20.5 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase MTS PF05175.14 EAU87979.2 - 0.006 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EAU87979.2 - 0.054 12.9 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DUF5133 PF17196.4 EAU87979.2 - 0.075 13.2 0.0 1.5 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) FtsJ PF01728.19 EAU87979.2 - 0.12 12.5 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase NodS PF05401.11 EAU87979.2 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Imm15 PF15561.6 EAU87980.1 - 0.041 14.1 0.1 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 15 zf-RING_2 PF13639.6 EAU87981.1 - 0.00099 19.4 5.2 0.0017 18.6 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAU87981.1 - 0.0048 16.7 3.9 0.008 16.0 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU87981.1 - 0.026 14.7 6.1 0.045 13.9 6.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EAU87981.1 - 0.068 13.0 5.1 0.12 12.2 5.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU87981.1 - 0.084 12.8 3.6 0.14 12.2 3.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAU87981.1 - 1.7 8.5 5.6 2.7 7.9 5.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Aminotran_3 PF00202.21 EAU87983.1 - 2.4e-113 378.8 0.0 5.7e-113 377.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EAU87983.1 - 0.0042 16.4 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EAU87983.1 - 0.0084 15.3 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_79C PF16862.5 EAU87987.2 - 5.3e-20 72.2 0.0 1.1e-19 71.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain PEMT PF04191.13 EAU87989.2 - 1.7e-53 179.4 10.0 4e-30 104.3 1.8 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 EAU87989.2 - 0.0098 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 ApoLp-III PF07464.11 EAU87989.2 - 0.014 15.5 0.6 0.027 14.6 0.6 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) SKICH PF17751.1 EAU87989.2 - 0.048 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 SKICH domain DUF4112 PF13430.6 EAU87989.2 - 0.45 10.8 1.8 21 5.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) 2OG-FeII_Oxy_2 PF13532.6 EAU87990.2 - 0.00054 20.2 0.0 0.00092 19.4 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 EAU87991.2 - 1.3e-42 146.1 0.0 1.8e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MvaI_BcnI PF15515.6 EAU87991.2 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family Amino_oxidase PF01593.24 EAU87992.1 - 1.6e-42 146.3 0.1 1.3e-41 143.4 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAU87992.1 - 8.7e-11 41.9 0.0 5e-10 39.5 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU87992.1 - 0.0037 16.5 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU87992.1 - 0.0046 16.1 0.5 0.0077 15.4 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EAU87992.1 - 0.028 13.5 0.2 0.072 12.2 0.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EAU87992.1 - 0.032 13.5 0.3 0.048 12.9 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EAU87992.1 - 0.043 13.1 1.0 0.068 12.4 1.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EAU87992.1 - 0.14 10.9 0.3 0.21 10.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EAU87992.1 - 0.18 11.2 0.4 0.27 10.5 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1996 PF09362.10 EAU87993.2 - 1.7e-78 263.8 0.3 2.4e-78 263.4 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PPR_2 PF13041.6 EAU87994.1 - 8.8e-09 35.4 0.0 0.00017 21.7 0.0 5.1 2 1 2 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EAU87994.1 - 7.9e-07 29.1 0.0 0.63 10.2 0.0 4.3 3 1 1 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 EAU87994.1 - 0.00073 19.6 4.5 1.6e+02 2.9 0.0 7.5 8 0 0 8 8 8 0 PPR repeat ATP13 PF12921.7 EAU87994.1 - 0.016 15.1 0.0 0.37 10.7 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ATPase expression Cyclin_N PF00134.23 EAU87995.2 - 3.9e-05 23.4 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain p450 PF00067.22 EAU87996.1 - 2e-43 148.8 0.0 2.4e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HATPase_c_2 PF13581.6 EAU87996.1 - 0.1 12.6 0.1 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain TFA2_Winged_2 PF18121.1 EAU88000.1 - 1.2e-20 73.0 0.0 2.4e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EAU88000.1 - 6.5e-18 64.8 0.2 3e-17 62.7 0.1 2.0 2 0 0 2 2 2 1 TFIIE beta subunit core domain Actino_peptide PF14408.6 EAU88000.1 - 3.1 8.0 11.3 27 5.0 0.1 2.8 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes Ricin_B_lectin PF00652.22 EAU88001.2 - 1.2e-09 38.5 0.2 2.1e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU88001.2 - 9.1e-09 35.9 0.1 1.7e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Yae1_N PF09811.9 EAU88002.1 - 6.9e-10 38.5 2.5 1.2e-09 37.7 2.5 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal F-box-like PF12937.7 EAU88003.2 - 3.2e-08 33.4 0.8 9.6e-08 31.8 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU88003.2 - 0.016 15.1 0.1 0.05 13.5 0.1 1.9 1 0 0 1 1 1 0 F-box domain Na_H_Exchanger PF00999.21 EAU88004.1 - 3.9e-68 230.0 38.8 4.9e-68 229.6 38.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Tim17 PF02466.19 EAU88004.1 - 0.0074 16.7 0.0 3.8 7.9 0.0 3.0 3 1 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_43 PF04616.14 EAU88005.2 - 6.1e-29 101.2 3.0 1.5e-27 96.7 3.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 RepA_N PF06970.11 EAU88005.2 - 0.15 12.0 0.3 38 4.3 0.0 3.2 3 0 0 3 3 3 0 Replication initiator protein A (RepA) N-terminus TPR_10 PF13374.6 EAU88006.1 - 2.5e-35 119.4 13.4 4.5e-06 26.4 0.3 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 EAU88006.1 - 1.6e-22 79.6 11.8 0.00085 19.6 0.1 8.9 6 1 4 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 EAU88006.1 - 1e-16 59.7 10.7 0.069 13.2 0.0 8.7 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 EAU88006.1 - 5.1e-14 51.7 0.8 0.0078 15.9 0.3 7.9 7 1 0 7 7 7 2 TPR repeat TPR_1 PF00515.28 EAU88006.1 - 9.5e-13 47.4 1.7 0.31 10.9 0.0 8.8 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU88006.1 - 4.6e-07 30.1 32.3 0.95 10.5 0.2 9.3 9 1 0 9 9 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 EAU88006.1 - 2.5e-06 28.0 4.5 6.9e-05 23.3 0.0 3.9 2 1 1 3 3 3 1 AAA ATPase domain TPR_2 PF07719.17 EAU88006.1 - 3e-06 26.9 15.0 0.42 10.8 0.1 9.0 10 1 0 10 10 8 1 Tetratricopeptide repeat AAA_22 PF13401.6 EAU88006.1 - 3.1e-06 27.5 0.1 0.00012 22.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EAU88006.1 - 3.1e-06 27.2 0.0 2.2e-05 24.4 0.0 2.6 1 1 0 1 1 1 1 NACHT domain TPR_17 PF13431.6 EAU88006.1 - 5.6e-06 26.4 0.6 11 6.7 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU88006.1 - 7.3e-06 25.8 0.5 5.3 7.5 0.0 7.1 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU88006.1 - 7.9e-06 26.4 14.9 0.068 13.8 0.3 6.3 3 1 3 6 6 6 3 Tetratricopeptide repeat MIT PF04212.18 EAU88006.1 - 8.5e-06 25.7 0.7 8.1 6.6 0.0 6.4 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain AAA_33 PF13671.6 EAU88006.1 - 0.00061 20.0 0.0 0.0021 18.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.6 EAU88006.1 - 0.00063 20.2 13.1 15 6.2 0.0 8.1 7 1 2 9 9 8 0 Tetratricopeptide repeat ATPase_2 PF01637.18 EAU88006.1 - 0.00081 19.4 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EAU88006.1 - 0.0042 16.3 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_6 PF13174.6 EAU88006.1 - 0.011 16.4 1.8 25 5.8 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat ArsR PF09824.9 EAU88006.1 - 0.012 15.2 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 ArsR transcriptional regulator RNA_helicase PF00910.22 EAU88006.1 - 0.022 15.2 0.0 0.089 13.2 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA PF00004.29 EAU88006.1 - 0.025 15.0 0.0 0.096 13.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Exonuc_VII_S PF02609.16 EAU88006.1 - 4.2 7.5 11.1 1.1e+02 2.9 0.0 5.9 6 0 0 6 6 6 0 Exonuclease VII small subunit F-box-like PF12937.7 EAU88007.1 - 5.1e-13 48.7 1.0 1.2e-12 47.5 1.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU88007.1 - 0.00031 21.1 1.6 10 6.7 0.1 5.6 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EAU88007.1 - 0.0011 18.8 0.8 0.0035 17.2 0.8 2.0 1 0 0 1 1 1 1 F-box domain Fib_alpha PF08702.10 EAU88007.1 - 0.13 12.4 0.3 0.25 11.5 0.3 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family G-alpha PF00503.20 EAU88009.2 - 2.5e-95 319.6 0.0 4.6e-95 318.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU88009.2 - 0.00037 20.0 0.8 2.4 7.6 0.1 3.2 3 0 0 3 3 3 2 ADP-ribosylation factor family TniB PF05621.11 EAU88009.2 - 0.0014 18.1 0.1 0.0033 16.8 0.0 1.7 2 0 0 2 2 2 1 Bacterial TniB protein Zeta_toxin PF06414.12 EAU88009.2 - 0.038 13.3 0.2 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Pox_A32 PF04665.12 EAU88009.2 - 0.086 12.3 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein HLH PF00010.26 EAU88010.2 - 3.3e-13 49.4 0.1 7e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC144C PF14915.6 EAU88010.2 - 0.037 13.1 3.6 0.058 12.5 3.6 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region YabA PF06156.13 EAU88010.2 - 0.41 11.3 2.6 0.38 11.4 1.0 1.8 2 0 0 2 2 2 0 Initiation control protein YabA DASH_Spc19 PF08287.11 EAU88010.2 - 1.2 9.0 5.0 2.3 8.1 5.0 1.5 1 0 0 1 1 1 0 Spc19 GMC_oxred_N PF00732.19 EAU88011.2 - 1.2e-52 179.1 0.0 1.5e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU88011.2 - 1.8e-33 116.1 0.0 2.8e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EAU88011.2 - 0.06 12.9 0.8 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU88011.2 - 0.084 13.1 0.5 0.22 11.8 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU88011.2 - 0.18 11.0 0.1 0.42 9.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU88011.2 - 0.22 10.5 0.2 0.31 10.0 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein 2TM PF13239.6 EAU88012.1 - 3.8 7.9 6.0 0.62 10.4 1.5 2.0 2 0 0 2 2 2 0 2TM domain SHR3_chaperone PF08229.11 EAU88014.2 - 0.21 10.5 0.4 8.2 5.4 0.0 2.4 2 0 0 2 2 2 0 ER membrane protein SH3 Bap31 PF05529.12 EAU88016.1 - 5e-44 149.4 4.6 7.1e-44 148.9 4.6 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EAU88016.1 - 2.5e-11 43.4 7.5 2.5e-11 43.4 7.5 1.7 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF883 PF05957.13 EAU88016.1 - 0.072 13.7 2.7 0.15 12.7 2.7 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RVT_1 PF00078.27 EAU88018.2 - 0.00013 21.6 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EAU88018.2 - 0.0037 18.0 0.1 0.0065 17.2 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Plavaka PF18759.1 EAU88020.1 - 2.7e-133 444.2 0.0 3.6e-133 443.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 EAU88020.1 - 0.00014 22.4 5.5 0.0028 18.4 1.2 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU88020.1 - 0.0007 19.9 2.1 0.0007 19.9 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EAU88020.1 - 0.0033 17.2 0.9 0.0076 16.0 0.9 1.6 1 0 0 1 1 1 1 zinc-finger C2H2-type Rnk_N PF14760.6 EAU88020.1 - 0.11 13.0 0.1 0.28 11.7 0.1 1.6 1 0 0 1 1 1 0 Rnk N-terminus zf-H2C2_2 PF13465.6 EAU88020.1 - 0.48 10.9 4.5 0.53 10.8 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 EAU88020.1 - 0.7 10.0 2.4 1.7 8.7 2.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger AP-5_subunit_s1 PF15001.6 EAU88021.2 - 7.4 6.5 6.3 13 5.7 0.0 2.5 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Transposase_21 PF02992.14 EAU88024.1 - 0.049 12.9 0.5 0.067 12.4 0.5 1.1 1 0 0 1 1 1 0 Transposase family tnp2 LTXXQ PF07813.12 EAU88026.1 - 0.1 13.4 2.8 4.4 8.1 0.2 2.6 2 0 0 2 2 2 0 LTXXQ motif family protein Asp_protease_2 PF13650.6 EAU88027.2 - 0.012 16.3 0.0 0.057 14.1 0.0 2.2 1 1 0 1 1 1 0 Aspartyl protease IL34 PF15036.6 EAU88027.2 - 0.075 13.1 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 Interleukin 34 gag-asp_proteas PF13975.6 EAU88027.2 - 0.097 13.2 0.0 0.35 11.5 0.0 2.0 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease PBP1_TM PF14812.6 EAU88027.2 - 1.2 9.5 4.6 5.2 7.5 4.6 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FXMRP1_C_core PF12235.8 EAU88029.1 - 0.11 13.1 1.9 0.23 12.1 1.9 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal MtaB PF12176.8 EAU88029.1 - 0.17 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Helicase_C PF00271.31 EAU88034.2 - 8.5e-13 48.6 0.0 1.7e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU88034.2 - 2.7e-07 30.5 0.1 5.2e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAU88034.2 - 0.023 14.7 0.0 0.097 12.7 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit zf-Di19 PF05605.12 EAU88034.2 - 2.2 8.7 11.6 0.069 13.5 3.7 2.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DPBB_1 PF03330.18 EAU88036.2 - 2.4e-05 24.5 0.1 4.9e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Lytic transglycolase DPBB_1 PF03330.18 EAU88037.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EAU88037.1 - 0.013 15.4 0.1 0.038 13.8 0.1 1.8 1 1 1 2 2 2 0 Barwin family DPBB_1 PF03330.18 EAU88038.1 - 2.2e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase SOG2 PF10428.9 EAU88039.2 - 0.058 12.6 1.9 0.057 12.6 1.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein E1-E2_ATPase PF00122.20 EAU88040.2 - 1.9e-53 180.7 5.2 2.2e-53 180.5 2.5 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAU88040.2 - 1e-46 158.9 8.2 1e-46 158.9 8.2 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAU88040.2 - 1.2e-21 78.0 1.8 1.3e-20 74.6 0.8 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAU88040.2 - 4e-20 71.3 0.3 3.7e-19 68.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EAU88040.2 - 4.4e-19 68.3 0.0 8.4e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU88040.2 - 1e-06 28.7 1.6 4e-06 26.8 1.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAU88040.2 - 2.1e-05 25.0 0.0 4.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 EAU88041.1 - 0.014 15.3 9.3 0.025 14.5 9.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 EAU88041.1 - 0.16 12.5 0.6 0.39 11.2 0.6 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain CBP4 PF07960.11 EAU88044.2 - 8.3e-13 48.3 0.0 8.9e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EAU88044.2 - 0.0032 17.4 0.5 0.0067 16.3 0.5 1.7 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 EamA PF00892.20 EAU88047.2 - 6.6e-08 32.8 13.8 1.9e-06 28.1 0.8 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EAU88047.2 - 8.2e-08 31.8 2.9 1.2e-07 31.2 2.9 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 EAU88047.2 - 3.9e-06 26.4 1.1 3.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 EAU88047.2 - 1.2e-05 24.7 1.4 1.7e-05 24.2 1.4 1.2 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 EAU88047.2 - 0.16 10.9 8.3 0.38 9.7 6.8 2.1 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like UPF0182 PF03699.13 EAU88047.2 - 0.97 7.5 2.9 0.47 8.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) SHQ1 PF04925.15 EAU88048.1 - 3.4e-57 192.8 0.0 5.1e-57 192.3 0.0 1.3 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.16 EAU88048.1 - 0.00035 21.5 0.0 0.00071 20.5 0.0 1.6 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 EAU88048.1 - 0.00069 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain ArsA_HSP20 PF17886.1 EAU88048.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Chorismate_bind PF00425.18 EAU88049.2 - 3.1e-89 299.0 0.0 4.8e-89 298.3 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EAU88049.2 - 3e-28 98.8 0.0 1.8e-27 96.3 0.0 2.4 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.20 EAU88050.1 - 8.5e-56 188.6 0.0 7.9e-33 113.5 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 AAA PF00004.29 EAU88052.1 - 2.9e-15 56.9 0.0 5.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EAU88052.1 - 8.1e-12 45.2 0.0 3.9e-10 39.7 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EAU88052.1 - 2e-10 40.9 0.0 5.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 EAU88052.1 - 1.4e-07 31.6 0.0 2.8e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EAU88052.1 - 3.2e-05 24.2 0.0 0.00012 22.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EAU88052.1 - 4.4e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 EAU88052.1 - 4.6e-05 23.9 0.1 0.00029 21.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EAU88052.1 - 5.5e-05 23.0 0.0 0.00019 21.2 0.0 1.9 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EAU88052.1 - 0.00017 21.4 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAU88052.1 - 0.0004 20.4 0.0 0.00096 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EAU88052.1 - 0.0014 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EAU88052.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EAU88052.1 - 0.002 17.5 0.0 0.045 13.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EAU88052.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EAU88052.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 EAU88052.1 - 0.0085 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EAU88052.1 - 0.01 16.2 0.0 0.073 13.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EAU88052.1 - 0.018 15.1 0.0 0.16 11.9 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DNA_pol3_delta PF06144.13 EAU88052.1 - 0.022 14.6 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF5338 PF17273.2 EAU88052.1 - 0.04 14.0 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) DUF815 PF05673.13 EAU88052.1 - 0.047 12.8 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 EAU88052.1 - 0.049 14.1 0.0 0.099 13.1 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EAU88052.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EAU88052.1 - 0.065 13.0 0.0 0.43 10.3 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 EAU88052.1 - 0.071 13.7 0.0 0.17 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU88052.1 - 0.14 11.7 0.2 0.35 10.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAU88052.1 - 0.15 12.5 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 EAU88052.1 - 0.18 11.2 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein CAF1A PF12253.8 EAU88053.1 - 3.3e-23 81.7 4.3 3.3e-23 81.7 4.3 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A PAP2 PF01569.21 EAU88054.2 - 2.2e-12 46.9 0.6 2.2e-12 46.9 0.6 2.1 3 0 0 3 3 3 1 PAP2 superfamily TNFR_16_TM PF18422.1 EAU88054.2 - 0.25 11.3 2.8 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Rpp20 PF12328.8 EAU88055.2 - 4.1e-05 23.5 0.0 8.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P MIF PF01187.18 EAU88060.2 - 9.7e-18 64.5 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Amidohydro_3 PF07969.11 EAU88062.2 - 3.1e-15 56.6 0.2 9.8e-07 28.6 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EAU88062.2 - 3.7e-14 52.8 0.1 4.6e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.12 EAU88062.2 - 0.023 14.6 0.3 7.3 6.7 0.2 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF1077 PF06417.12 EAU88063.2 - 1.4e-46 157.4 0.4 1.7e-46 157.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RRM_1 PF00076.22 EAU88064.2 - 3.9e-35 119.5 0.0 2.8e-19 68.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU88064.2 - 0.049 13.7 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif OB_RNB PF08206.11 EAU88064.2 - 0.083 12.6 0.2 0.94 9.2 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_5 PF13893.6 EAU88064.2 - 0.11 12.1 0.0 12 5.5 0.0 2.2 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 EAU88065.1 - 8.3e-54 181.6 0.0 9.5e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU88065.1 - 4.1e-19 69.0 0.0 5.5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU88065.1 - 3.7e-07 29.8 0.0 4.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAU88065.1 - 0.04 13.5 0.1 0.28 10.7 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 EAU88065.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial F-box PF00646.33 EAU88068.2 - 0.0036 17.1 0.3 0.0084 16.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU88068.2 - 0.073 13.0 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF1059 PF06348.11 EAU88068.2 - 0.099 12.9 0.4 1 9.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Phosducin PF02114.16 EAU88070.1 - 2.5e-07 29.9 0.0 3.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin DUF3886 PF13025.6 EAU88070.1 - 0.0018 18.4 0.9 0.0018 18.4 0.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3886) PsbJ PF01788.17 EAU88072.2 - 0.072 13.0 0.9 14 5.7 0.0 2.5 2 0 0 2 2 2 0 PsbJ GH-E PF14410.6 EAU88073.2 - 0.14 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Aminotran_5 PF00266.19 EAU88074.1 - 8.4e-35 120.4 0.0 1.1e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Troponin-I_N PF11636.8 EAU88075.2 - 0.12 12.3 0.8 0.12 12.3 0.8 3.4 3 1 1 4 4 4 0 Troponin I residues 1-32 DUF3603 PF12227.8 EAU88076.2 - 0.023 14.0 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Cutinase PF01083.22 EAU88080.1 - 2.1e-42 145.1 0.0 2.5e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 EAU88080.1 - 2.9e-07 30.4 0.0 4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.11 EAU88080.1 - 2.7e-05 23.8 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 EAU88080.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_8 PF06259.12 EAU88080.1 - 0.046 13.4 0.1 0.074 12.7 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase VirJ PF06057.11 EAU88080.1 - 0.065 13.1 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) TRAPPC10 PF12584.8 EAU88081.2 - 1.1e-44 151.9 0.0 2.3e-44 150.9 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DEAD PF00270.29 EAU88082.1 - 7e-48 162.7 0.0 1.1e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU88082.1 - 8.4e-31 106.6 0.1 2.7e-30 105.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU88082.1 - 2.8e-06 27.4 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAU88082.1 - 0.031 14.6 0.0 0.091 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Cellulase PF00150.18 EAU88084.2 - 1.4e-17 64.1 0.0 2.7e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TBP PF00352.21 EAU88086.1 - 1.3e-65 217.4 2.8 3.8e-32 110.1 0.1 2.7 3 0 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EAU88086.1 - 0.00056 20.0 4.5 0.37 10.9 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) Spt20 PF12090.8 EAU88086.1 - 0.0044 16.7 16.7 0.006 16.2 16.7 1.2 1 0 0 1 1 1 1 Spt20 family DUF2722 PF10846.8 EAU88086.1 - 0.15 11.0 13.5 0.2 10.6 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Ndc1_Nup PF09531.10 EAU88086.1 - 0.41 9.3 8.1 0.44 9.2 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM51 PF15345.6 EAU88086.1 - 0.76 9.6 8.7 1.1 9.0 8.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CDK2AP PF09806.9 EAU88086.1 - 2.8 7.9 9.4 24 4.9 10.2 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF4834 PF16118.5 EAU88086.1 - 2.9 8.9 6.4 7.4 7.6 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Dynamin_M PF01031.20 EAU88087.1 - 2.2e-100 335.6 0.0 2e-99 332.4 0.0 2.4 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 EAU88087.1 - 5.6e-56 189.2 0.0 1.1e-55 188.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAU88087.1 - 3.4e-29 100.9 3.9 6.9e-29 99.8 3.9 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAU88087.1 - 6.6e-05 23.0 0.1 0.00074 19.6 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_88 PF07470.13 EAU88088.1 - 6.5e-20 71.5 0.1 8.6e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 EAU88088.1 - 0.0046 16.5 0.3 0.012 15.1 0.1 1.6 1 1 1 2 2 2 1 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 EAU88088.1 - 0.028 13.7 0.7 1.9 7.7 0.0 2.9 1 1 1 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 EAU88088.1 - 0.096 11.2 0.1 0.97 7.9 0.1 2.0 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 NTF2 PF02136.20 EAU88089.1 - 8.9e-36 123.1 0.0 9.9e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Helicase_C PF00271.31 EAU88091.2 - 2.8e-08 34.1 0.0 4.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Linker_histone PF00538.19 EAU88093.2 - 0.00026 21.3 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family SAP PF02037.27 EAU88094.2 - 4.4e-06 26.3 0.9 2.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 SAP domain YacG PF03884.14 EAU88094.2 - 0.22 11.3 1.4 22 4.9 0.0 2.8 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Prok-RING_1 PF14446.6 EAU88094.2 - 0.4 10.6 2.2 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4192 PF13830.6 EAU88094.2 - 1.5 8.8 5.6 1.1 9.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) zf-H2C2_2 PF13465.6 EAU88094.2 - 6.8 7.3 9.1 19 5.9 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double domain FeS_assembly_P PF01883.19 EAU88096.2 - 6.7e-13 48.6 0.1 1.4e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Cullin_binding PF03556.15 EAU88097.2 - 4.8e-26 91.6 2.4 8.8e-26 90.7 2.4 1.4 1 0 0 1 1 1 1 Cullin binding P5CR_dimer PF14748.6 EAU88098.1 - 8.8e-39 131.9 1.8 1.8e-38 131.0 1.8 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EAU88098.1 - 4.6e-12 46.3 0.0 2.5e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent FAM60A PF15396.6 EAU88100.2 - 0.13 12.2 5.9 0.056 13.5 2.3 1.9 1 1 1 2 2 2 0 Protein Family FAM60A Macoilin PF09726.9 EAU88100.2 - 1.2 7.6 8.1 1.4 7.4 8.1 1.1 1 0 0 1 1 1 0 Macoilin family SRP-alpha_N PF04086.13 EAU88100.2 - 3 7.7 11.0 4.1 7.2 11.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAP2 PF01569.21 EAU88101.2 - 5.4e-24 84.5 2.8 5.4e-24 84.5 2.8 2.1 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 EAU88101.2 - 0.0011 19.5 2.2 0.0059 17.1 0.4 2.6 2 0 0 2 2 2 1 PAP2 superfamily C-terminal DPM3 PF08285.11 EAU88101.2 - 0.47 10.7 3.9 0.31 11.2 0.7 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PAP2_3 PF14378.6 EAU88101.2 - 0.84 9.3 11.5 27 4.4 11.5 2.9 1 1 0 1 1 1 0 PAP2 superfamily PAP2 PF01569.21 EAU88102.1 - 9.8e-26 90.1 4.6 9.8e-26 90.1 4.6 1.9 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 EAU88102.1 - 0.026 15.0 1.2 0.026 15.0 1.2 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Spc24 PF08286.11 EAU88103.1 - 6.6e-21 74.5 0.3 9.1e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF1845 PF08900.11 EAU88103.1 - 0.049 13.4 0.4 0.08 12.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) FAM76 PF16046.5 EAU88103.1 - 0.43 9.9 1.8 0.6 9.4 1.8 1.2 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 EAU88103.1 - 2 8.2 7.3 6.4 6.5 7.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Ferritin PF00210.24 EAU88103.1 - 2.3 8.2 8.1 0.43 10.5 2.2 2.5 2 1 0 2 2 2 0 Ferritin-like domain DUF2098 PF09871.9 EAU88103.1 - 4.3 7.7 5.2 2.8 8.4 1.0 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) AAA_13 PF13166.6 EAU88103.1 - 6.2 5.3 8.7 21 3.6 8.7 1.7 1 1 0 1 1 1 0 AAA domain DPBB_1 PF03330.18 EAU88104.2 - 0.00011 22.5 0.0 0.00021 21.5 0.0 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EAU88104.2 - 0.043 13.7 0.0 0.087 12.7 0.0 1.5 1 1 0 1 1 1 0 Barwin family SOG2 PF10428.9 EAU88104.2 - 0.14 11.4 8.6 0.17 11.0 8.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mucin PF01456.17 EAU88104.2 - 0.72 9.8 29.9 1.2 9.1 29.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1218 PF06749.12 EAU88105.2 - 0.35 11.4 18.0 0.99 10.0 0.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) DAGK_cat PF00781.24 EAU88106.1 - 6e-15 55.0 0.0 2.1e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain FH2 PF02181.23 EAU88107.2 - 6.1e-70 236.2 14.7 3.4e-69 233.7 4.7 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_GBD PF06371.13 EAU88107.2 - 3.3e-36 124.6 0.3 3.3e-36 124.6 0.3 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EAU88107.2 - 2.2e-32 112.3 2.8 4.2e-32 111.3 0.0 2.7 2 1 1 3 3 3 1 Diaphanous FH3 Domain YjcZ PF13990.6 EAU88107.2 - 0.0061 16.0 2.9 0.02 14.3 2.9 1.9 1 0 0 1 1 1 1 YjcZ-like protein Cortex-I_coil PF09304.10 EAU88107.2 - 0.43 10.8 14.0 0.064 13.5 4.0 3.8 3 0 0 3 3 3 0 Cortexillin I, coiled coil Fib_alpha PF08702.10 EAU88107.2 - 1.1 9.5 7.8 1 9.5 0.2 4.2 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Prominin PF05478.11 EAU88107.2 - 3.3 5.6 6.0 0.38 8.6 0.4 2.0 2 0 0 2 2 2 0 Prominin Med9 PF07544.13 EAU88107.2 - 3.7 7.7 9.8 0.14 12.2 0.9 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 EAU88107.2 - 8.3 6.8 14.9 9.6 6.6 0.0 4.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myosin_head PF00063.21 EAU88108.2 - 7.8e-260 863.8 0.6 2.6e-259 862.1 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 EAU88108.2 - 4.2e-26 91.2 2.0 4.2e-26 91.2 2.0 3.4 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 EAU88108.2 - 1.2e-10 40.2 33.6 0.012 15.3 0.4 7.1 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 EAU88108.2 - 0.00031 20.5 2.8 0.00064 19.5 2.5 1.7 1 1 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EAU88108.2 - 0.031 14.5 2.5 0.086 13.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain SNCAIP_SNCA_bd PF16700.5 EAU88108.2 - 0.16 11.7 6.5 0.56 10.0 6.5 1.9 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain AAA_16 PF13191.6 EAU88108.2 - 0.28 11.5 0.0 0.28 11.5 0.0 3.0 2 1 0 2 2 1 0 AAA ATPase domain Fib_alpha PF08702.10 EAU88108.2 - 0.33 11.1 19.4 0.16 12.2 14.7 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF572 PF04502.13 EAU88108.2 - 0.98 9.0 16.4 2 7.9 16.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF724 PF05266.14 EAU88108.2 - 3.3 7.5 25.0 1.1 9.0 6.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Phlebovirus_NSM PF07246.11 EAU88108.2 - 4.6 6.5 12.5 10 5.4 12.5 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ING PF12998.7 EAU88108.2 - 6.9 7.3 12.7 28 5.4 12.7 2.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-AN1 PF01428.16 EAU88109.2 - 5.4e-17 61.7 25.8 1.5e-09 37.8 10.2 2.3 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EAU88109.2 - 0.0033 17.6 3.8 0.0033 17.6 3.8 2.8 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain Snf7 PF03357.21 EAU88110.1 - 8.4e-41 139.4 21.2 2.3e-40 138.0 20.0 1.9 2 0 0 2 2 2 1 Snf7 HTH_6 PF01418.17 EAU88110.1 - 0.066 13.2 1.4 0.24 11.4 0.7 2.1 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family YlqD PF11068.8 EAU88110.1 - 0.53 10.7 13.8 0.76 10.2 5.9 2.1 1 1 1 2 2 2 0 YlqD protein DUF4407 PF14362.6 EAU88110.1 - 0.65 9.3 5.3 0.93 8.8 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EAU88110.1 - 3.4 7.2 10.3 4.5 6.7 10.2 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 EAU88110.1 - 6.7 6.8 14.2 0.4 10.8 8.3 2.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 EAU88110.1 - 8 6.6 10.5 0.74 9.9 4.3 2.3 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 COG4 PF08318.12 EAU88111.1 - 2.5e-89 299.7 0.0 3.6e-89 299.2 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein Lambda_CIII PF02061.16 EAU88111.1 - 0.053 13.6 0.1 0.33 11.1 0.1 2.4 1 1 0 1 1 1 0 Lambda Phage CIII ORF6C PF10552.9 EAU88111.1 - 0.11 12.6 0.2 0.34 11.0 0.2 1.8 1 0 0 1 1 1 0 ORF6C domain ECM11 PF15463.6 EAU88111.1 - 0.76 10.4 3.0 56 4.3 0.3 3.8 3 1 0 3 3 3 0 Extracellular mutant protein 11 Glyco_hydro_3_C PF01915.22 EAU88112.2 - 3.1e-59 200.3 0.0 4.9e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EAU88112.2 - 1.5e-47 162.6 0.0 2.8e-47 161.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EAU88112.2 - 4.9e-19 68.2 0.0 2.1e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EAU88112.2 - 3.2e-13 49.7 0.0 5.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.9 EAU88112.2 - 0.005 15.7 0.0 0.0077 15.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein CARDB PF07705.11 EAU88112.2 - 0.11 12.8 0.1 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 CARDB DUF2340 PF10209.9 EAU88113.1 - 1.1e-53 180.8 2.7 1.2e-53 180.6 2.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 EAU88113.1 - 6.4e-06 26.6 0.4 7.8e-06 26.3 0.4 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain DnaJ_C PF01556.18 EAU88114.1 - 4.8e-41 140.3 0.6 6.1e-41 140.0 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAU88114.1 - 7.8e-22 77.2 0.4 2e-21 75.9 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAU88114.1 - 8.7e-17 61.3 18.6 1.4e-16 60.6 18.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EAU88114.1 - 0.0026 17.7 17.2 0.022 14.7 4.1 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EAU88114.1 - 4.4 7.4 11.5 6 6.9 2.2 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CN_hydrolase PF00795.22 EAU88115.2 - 2.8e-46 158.0 0.0 6.6e-44 150.2 0.0 2.0 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase PALP PF00291.25 EAU88116.2 - 6.8e-63 212.8 0.0 8.3e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PrpR_N PF06506.11 EAU88116.2 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Propionate catabolism activator YjeF_N PF03853.15 EAU88116.2 - 0.12 12.2 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Pet100 PF09803.9 EAU88117.1 - 9.4e-28 96.6 0.0 1.3e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Pet100 Luteo_PO PF04662.13 EAU88117.1 - 0.019 14.6 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Luteovirus P0 protein Cwf_Cwc_15 PF04889.12 EAU88117.1 - 0.13 12.0 4.2 0.15 11.8 4.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1192 PF06698.11 EAU88117.1 - 0.15 12.1 5.6 0.19 11.8 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) EF-1_beta_acid PF10587.9 EAU88117.1 - 1.2 9.6 7.9 4.1 8.0 7.9 1.9 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Pyridoxal_deC PF00282.19 EAU88118.1 - 2.9e-62 210.6 0.0 4.2e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4407 PF14362.6 EAU88119.1 - 0.022 14.1 0.1 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BSD PF03909.17 EAU88119.1 - 2.1 8.4 4.3 1.2 9.2 0.4 2.4 2 0 0 2 2 2 0 BSD domain DNA_pol_D_N PF18018.1 EAU88120.2 - 3.5e-43 146.8 0.0 5.4e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 EAU88120.2 - 5.4e-29 101.1 0.0 1e-27 96.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B EAP30 PF04157.16 EAU88121.1 - 5.2e-68 228.8 0.0 6e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Exonuc_VII_L PF02601.15 EAU88121.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Viral_cys_rich PF08008.12 EAU88121.1 - 0.18 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Viral cysteine rich PBP PF01161.20 EAU88122.1 - 7.3e-12 45.7 0.0 1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Hid1 PF12722.7 EAU88123.2 - 9.3e-159 530.1 0.0 1.3e-158 529.6 0.0 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EAU88123.2 - 7.9e-75 252.5 0.0 1e-74 252.1 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DAZAP2 PF11029.8 EAU88123.2 - 0.11 13.4 0.2 0.11 13.4 0.2 3.4 4 0 0 4 4 4 0 DAZ associated protein 2 (DAZAP2) PBP PF01161.20 EAU88124.1 - 2.1e-10 41.0 0.1 3.4e-10 40.4 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein G-patch PF01585.23 EAU88125.2 - 4.8e-14 52.0 1.8 1.1e-13 50.8 1.8 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EAU88125.2 - 2.7e-06 27.1 0.8 0.0053 16.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EAU88125.2 - 1.1e-05 25.4 3.9 2.3e-05 24.4 2.2 2.5 2 0 0 2 2 2 1 G-patch domain RED_N PF07808.13 EAU88125.2 - 0.0067 16.0 0.4 0.021 14.4 0.4 1.9 1 0 0 1 1 1 1 RED-like protein N-terminal region NDUF_B4 PF07225.12 EAU88126.1 - 0.00012 21.9 0.1 0.00013 21.8 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF2544 PF11245.8 EAU88126.1 - 0.021 14.3 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) COQ7 PF03232.13 EAU88127.1 - 3.5e-70 235.2 0.6 4.2e-70 235.0 0.6 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 WD40 PF00400.32 EAU88129.2 - 1.2e-44 149.4 25.5 1.9e-08 34.8 0.4 8.9 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EAU88129.2 - 1.2e-14 53.9 1.1 2.2e-14 53.1 1.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU88129.2 - 1.5e-11 43.9 0.2 3e-11 42.9 0.2 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EAU88129.2 - 3.4e-07 30.5 1.4 0.19 12.1 0.1 5.1 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAU88129.2 - 6.4e-07 28.4 13.8 1.6 7.3 0.0 6.1 3 2 3 6 6 6 5 Nucleoporin Nup120/160 F-box_4 PF15966.5 EAU88129.2 - 0.0002 21.2 0.0 0.00086 19.2 0.0 2.1 1 0 0 1 1 1 1 F-box Pkinase PF00069.25 EAU88130.2 - 6.8e-65 219.0 0.0 8e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU88130.2 - 2.6e-25 89.2 0.0 3.4e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU88130.2 - 9.8e-05 21.8 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAU88130.2 - 0.00077 19.5 0.1 0.044 13.7 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAU88130.2 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 EAU88130.2 - 0.066 12.8 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EAU88130.2 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactamase_B_2 PF12706.7 EAU88134.1 - 4.7e-08 32.8 0.0 0.00017 21.1 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAU88134.1 - 0.00065 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 EAU88134.1 - 0.0059 15.8 0.0 0.024 13.7 0.0 1.9 3 0 0 3 3 3 1 cAMP phosphodiesterases class-II Phageshock_PspG PF09583.10 EAU88134.1 - 1.3 9.3 7.1 2.6 8.4 7.1 1.4 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) CoA_transf_3 PF02515.17 EAU88136.2 - 0.0078 15.4 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III HTH_31 PF13560.6 EAU88136.2 - 0.11 12.8 0.0 0.35 11.3 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain Linker_histone PF00538.19 EAU88138.2 - 1.2e-21 76.8 0.0 1.2e-21 76.8 0.0 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family AMP-binding PF00501.28 EAU88139.1 - 1.6e-16 60.0 0.0 1.2e-15 57.0 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.19 EAU88141.2 - 2.2e-23 82.4 2.5 2.6e-23 82.2 0.0 2.4 2 0 0 2 2 2 1 linker histone H1 and H5 family Telomere_reg-2 PF10193.9 EAU88142.1 - 2.4e-32 111.6 0.0 8e-32 109.9 0.0 2.0 1 0 0 1 1 1 1 Telomere length regulation protein DAP_epimerase PF01678.19 EAU88142.1 - 0.2 11.8 0.1 0.4 10.9 0.1 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase 2Fe-2S_thioredx PF01257.19 EAU88143.2 - 8.5e-60 200.8 0.1 1.1e-59 200.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.21 EAU88144.1 - 2.4e-42 145.3 0.0 4.9e-22 78.7 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2198 PF09964.9 EAU88144.1 - 3.7 7.7 6.2 0.75 9.9 1.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) Tower PF09121.10 EAU88145.2 - 0.38 11.0 4.4 0.15 12.2 0.5 2.3 2 0 0 2 2 2 0 Tower Glyco_hydro_63 PF03200.16 EAU88146.2 - 1.1e-151 505.9 0.4 2.3e-149 498.3 0.4 2.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EAU88146.2 - 1.2e-65 221.8 0.3 4.1e-65 220.1 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EAU88146.2 - 0.0043 15.9 0.3 0.014 14.2 0.0 1.8 2 0 0 2 2 2 1 Trehalase Band_7 PF01145.25 EAU88147.1 - 0.00011 22.2 0.0 0.00011 22.2 0.0 3.7 3 1 0 3 3 3 1 SPFH domain / Band 7 family Atg8 PF02991.16 EAU88148.1 - 6.2e-52 174.1 0.2 7.3e-52 173.9 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EAU88148.1 - 3.9e-07 30.4 0.0 4.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad51 PF08423.11 EAU88150.2 - 8e-38 130.1 0.0 1.2e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EAU88150.2 - 8.1e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EAU88150.2 - 3.7e-05 23.3 0.3 0.00079 19.0 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 EAU88150.2 - 0.0012 18.3 0.2 0.0078 15.6 0.2 2.1 1 1 0 1 1 1 1 KaiC ABC_tran PF00005.27 EAU88150.2 - 0.14 12.6 0.2 0.28 11.7 0.2 1.8 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EAU88150.2 - 0.14 12.3 0.1 0.75 10.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 EAU88152.1 - 0.0011 18.9 5.8 0.034 14.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU88152.1 - 0.0016 18.1 0.8 0.4 10.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU88152.1 - 0.12 12.7 3.4 1.5 9.2 0.0 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU88152.1 - 0.19 12.0 1.5 0.9 9.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU88152.1 - 0.26 11.4 3.3 1 9.6 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAU88152.1 - 0.28 11.9 6.5 9.5 7.0 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU88152.1 - 0.32 11.9 5.0 3.1 8.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EAU88152.1 - 0.95 9.6 10.1 0.3 11.2 2.4 2.9 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain SMBP PF16785.5 EAU88152.1 - 8.8 6.6 10.0 4.3 7.6 6.8 2.0 2 1 0 2 2 2 0 Small metal-binding protein NYN PF01936.18 EAU88153.1 - 1.7e-05 25.3 0.0 4.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 NYN domain CHCH PF06747.13 EAU88154.1 - 8.2e-05 22.6 0.8 0.0001 22.3 0.8 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EAU88154.1 - 0.031 14.3 0.2 0.043 13.8 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UQ_con PF00179.26 EAU88155.2 - 1.7e-19 69.9 0.0 2.7e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAU88155.2 - 0.053 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 RWD domain Vps36-NZF-N PF16988.5 EAU88155.2 - 0.076 12.4 0.1 0.076 12.4 0.1 2.3 3 0 0 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EAU88155.2 - 0.095 12.8 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 EAU88155.2 - 0.63 9.4 5.3 0.099 12.0 0.6 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRP21_like_P PF12230.8 EAU88157.1 - 1.4e-50 172.2 10.7 1.4e-50 172.2 10.7 2.4 3 1 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EAU88157.1 - 1.4e-35 121.0 0.6 1.7e-16 59.9 0.0 2.7 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EAU88157.1 - 7.1e-10 38.5 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 EAU88157.1 - 0.00011 21.8 0.2 0.00021 20.8 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Rad60-SLD PF11976.8 EAU88157.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAU88157.1 - 0.043 14.4 0.8 0.14 12.7 0.1 2.3 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain L31 PF09784.9 EAU88158.1 - 3.1e-41 139.9 0.1 3.4e-41 139.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.6 EAU88159.1 - 8.5e-107 356.2 4.5 1e-106 355.9 4.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RNase_T PF00929.24 EAU88160.2 - 1.3e-16 61.6 0.0 6.8e-16 59.2 0.0 1.9 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EAU88160.2 - 0.00089 19.3 0.0 0.0052 16.8 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like CDP-OH_P_tran_2 PF08009.11 EAU88160.2 - 0.16 11.9 5.4 0.38 10.7 5.4 1.7 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 Ndc80_HEC PF03801.13 EAU88162.2 - 1.9e-33 115.2 0.0 4.6e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 EAU88162.2 - 0.00075 19.5 2.8 0.00075 19.5 2.8 3.8 4 1 0 4 4 4 1 Domain of unknown function (DUF5595) Phage_GP20 PF06810.11 EAU88162.2 - 0.0047 16.7 4.7 0.0047 16.7 4.7 3.5 2 2 1 3 3 3 1 Phage minor structural protein GP20 DUF5588 PF17826.1 EAU88162.2 - 0.016 14.2 0.4 0.016 14.2 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5588) CDT1_C PF16679.5 EAU88162.2 - 0.16 12.4 4.2 1.8 9.0 0.2 3.5 3 0 0 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Cor1 PF04803.12 EAU88162.2 - 0.26 11.5 0.1 0.26 11.5 0.1 3.7 4 1 0 4 4 4 0 Cor1/Xlr/Xmr conserved region DUF2935 PF11155.8 EAU88162.2 - 0.37 11.1 3.4 8.5 6.7 0.2 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) Lebercilin PF15619.6 EAU88162.2 - 0.59 9.8 32.1 0.84 9.3 1.3 3.9 2 2 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Mce4_CUP1 PF11887.8 EAU88162.2 - 0.84 9.0 6.0 6.7 6.1 0.2 2.7 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative ZnuA PF01297.17 EAU88162.2 - 3.4 7.0 8.5 0.17 11.3 1.9 2.1 3 0 0 3 3 3 0 Zinc-uptake complex component A periplasmic Laminin_II PF06009.12 EAU88162.2 - 4.2 7.4 21.7 1.2 9.2 3.0 3.6 2 2 2 4 4 4 0 Laminin Domain II DUF724 PF05266.14 EAU88162.2 - 6.3 6.6 23.6 7 6.4 2.1 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF724) COG5 PF10392.9 EAU88162.2 - 6.9 6.9 15.5 2.4 8.4 8.1 3.5 2 2 1 3 3 3 0 Golgi transport complex subunit 5 Fib_alpha PF08702.10 EAU88162.2 - 8.3 6.6 22.0 4.9 7.3 1.2 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family FapA PF03961.13 EAU88162.2 - 8.8 4.8 22.3 2.4 6.7 10.5 3.1 1 1 1 3 3 3 0 Flagellar Assembly Protein A Mog1 PF04603.12 EAU88163.2 - 3e-41 141.0 0.1 3.6e-41 140.8 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein CCDC-167 PF15188.6 EAU88164.2 - 0.0017 18.6 6.4 0.12 12.7 1.1 2.6 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 Cnn_1N PF07989.11 EAU88164.2 - 0.0093 16.1 13.9 0.48 10.6 0.2 2.9 3 0 0 3 3 3 2 Centrosomin N-terminal motif 1 DUF2383 PF09537.10 EAU88164.2 - 0.0094 16.3 1.0 0.036 14.4 1.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF4407 PF14362.6 EAU88164.2 - 0.14 11.5 3.9 0.084 12.2 2.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 EAU88164.2 - 0.54 10.5 13.8 0.17 12.1 0.9 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 EAU88164.2 - 0.74 10.3 0.0 0.74 10.3 0.0 3.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) Ead_Ea22 PF13935.6 EAU88164.2 - 0.74 10.5 7.0 2.4 8.8 4.1 2.4 2 0 0 2 2 2 0 Ead/Ea22-like protein GAGA_bind PF06217.12 EAU88164.2 - 0.98 9.6 7.0 1.6 8.9 7.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Tli4_N PF18443.1 EAU88164.2 - 1.4 9.3 5.1 1.8 9.0 1.0 2.8 3 0 0 3 3 3 0 Tle cognate immunity protein 4 N-terminal domain Fib_alpha PF08702.10 EAU88164.2 - 2.9 8.1 4.9 1.3 9.2 1.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3496 PF12001.8 EAU88164.2 - 3.3 8.1 10.5 2.1 8.8 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Spectrin PF00435.21 EAU88164.2 - 5.8 7.5 11.3 4.5 7.8 3.3 2.8 3 0 0 3 3 3 0 Spectrin repeat HrpB7 PF09486.10 EAU88164.2 - 8.2 6.8 15.4 14 6.0 3.7 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FapA PF03961.13 EAU88164.2 - 8.2 4.9 7.9 9.3 4.7 5.0 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A TBCA PF02970.16 EAU88164.2 - 8.8 6.7 12.9 29 5.1 0.2 3.6 3 1 0 3 3 3 0 Tubulin binding cofactor A KELK PF15796.5 EAU88164.2 - 9.2 6.8 19.7 3.9 8.0 6.0 2.8 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DivIVA PF05103.13 EAU88164.2 - 9.7 6.3 20.0 4.6 7.3 2.0 2.8 3 0 0 3 3 3 0 DivIVA protein Filament PF00038.21 EAU88164.2 - 9.8 5.7 16.6 0.13 11.9 3.7 2.7 3 0 0 3 3 3 0 Intermediate filament protein HECT PF00632.25 EAU88165.2 - 5e-94 315.2 0.0 6.6e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EAU88165.2 - 3.2e-37 126.3 19.6 1.1e-12 47.9 6.6 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 EAU88165.2 - 5.3e-20 71.6 0.1 1.4e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 C2 domain DUF5611 PF18446.1 EAU88165.2 - 0.12 13.2 0.2 0.44 11.4 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5611) Lin-8 PF03353.15 EAU88165.2 - 5.3 6.5 7.6 8.5 5.8 7.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pox_MCEL PF03291.16 EAU88166.2 - 3.6e-87 292.6 0.0 4.8e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EAU88166.2 - 3.4e-12 46.9 0.0 9.2e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU88166.2 - 9.4e-09 35.2 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU88166.2 - 9.1e-08 32.7 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU88166.2 - 6.8e-07 30.0 0.0 1.9e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU88166.2 - 5.9e-06 26.2 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU88166.2 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 EAU88166.2 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family ERAP1_C PF11838.8 EAU88167.2 - 3.7e-74 250.1 0.2 7.1e-74 249.2 0.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EAU88167.2 - 1.4e-67 227.4 0.2 2.7e-67 226.5 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EAU88167.2 - 3.1e-48 164.4 0.3 1.1e-46 159.3 0.3 2.3 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3287 PF11690.8 EAU88167.2 - 0.021 14.6 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) NYN PF01936.18 EAU88168.2 - 1.4e-05 25.6 0.0 3.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NYN domain NYN PF01936.18 EAU88169.2 - 3.9e-05 24.2 0.0 7.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NYN domain NYN PF01936.18 EAU88170.1 - 6.9e-11 42.8 0.0 1.3e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 NYN domain NYN PF01936.18 EAU88171.1 - 1e-11 45.6 0.0 1.5e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 NYN domain PAM2 PF07145.15 EAU88171.1 - 0.024 14.3 0.3 0.061 13.0 0.3 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region NYN PF01936.18 EAU88172.1 - 8.1e-05 23.1 0.1 0.00015 22.3 0.1 1.4 1 0 0 1 1 1 1 NYN domain DUF1980 PF09323.10 EAU88177.1 - 0.17 11.8 0.7 0.48 10.3 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Cwf_Cwc_15 PF04889.12 EAU88177.1 - 3.6 7.3 24.1 0.52 10.0 10.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.10 EAU88177.1 - 3.6 7.9 8.7 11 6.3 1.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 EAU88177.1 - 4.9 6.0 15.2 0.36 9.8 2.5 2.1 2 0 0 2 2 2 0 Paf1 CENP-B_dimeris PF09026.10 EAU88177.1 - 5.2 7.5 20.5 0.029 14.8 10.5 2.3 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Pyr_redox_2 PF07992.14 EAU88178.1 - 6.1e-66 222.6 0.4 1e-65 221.9 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EAU88178.1 - 3.5e-33 114.2 0.2 1.1e-32 112.5 0.1 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EAU88178.1 - 8.7e-21 74.3 3.3 2.9e-18 66.2 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU88178.1 - 3.8e-17 62.5 0.4 9.3e-16 57.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU88178.1 - 4.2e-07 29.0 0.9 0.0022 16.8 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EAU88178.1 - 7.9e-07 28.8 0.4 1.5e-06 27.8 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EAU88178.1 - 1.2e-05 24.6 0.0 2.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EAU88178.1 - 3.2e-05 23.2 2.9 0.0048 16.0 1.6 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EAU88178.1 - 0.00048 20.3 0.9 0.0014 18.9 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU88178.1 - 0.0041 16.8 10.7 0.026 14.1 0.9 2.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAU88178.1 - 0.014 15.4 1.2 0.13 12.3 0.0 2.8 2 1 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 EAU88178.1 - 0.036 13.4 1.0 0.72 9.2 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 EAU88178.1 - 0.11 11.7 0.1 1.5 8.0 0.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 EAU88178.1 - 0.11 12.9 0.1 16 6.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 EAU88178.1 - 0.84 8.6 8.8 0.096 11.7 0.2 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 EAU88178.1 - 2.4 8.0 10.3 0.33 10.8 0.1 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PIN_4 PF13638.6 EAU88181.2 - 3.5e-23 82.3 0.2 3.5e-23 82.3 0.2 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 EAU88181.2 - 8.6e-11 41.8 0.0 6.2e-06 25.9 0.0 2.5 2 1 0 2 2 2 2 Est1 DNA/RNA binding domain Ax_dynein_light PF10211.9 EAU88181.2 - 1.4 8.8 8.2 0.11 12.4 1.8 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Cytochrom_B561 PF03188.16 EAU88182.2 - 2.2e-09 37.6 1.2 4e-09 36.7 1.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 EAU88182.2 - 6.7e-08 32.4 0.2 7.1e-07 29.1 0.2 2.2 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 EAU88182.2 - 0.0013 18.5 0.5 0.0092 15.8 0.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EAU88182.2 - 0.003 17.7 1.4 0.045 13.9 1.4 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DOMON PF03351.17 EAU88182.2 - 0.02 15.1 2.4 0.021 15.0 0.1 2.0 2 0 0 2 2 2 0 DOMON domain DUF2798 PF11391.8 EAU88182.2 - 4.4 7.4 9.0 3.4 7.8 2.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2798) NDK PF00334.19 EAU88183.1 - 2.5e-53 179.7 0.0 2.8e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase UCR_14kD PF02271.16 EAU88184.1 - 4.9e-41 138.8 1.0 5.7e-41 138.5 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.21 EAU88185.1 - 2.2e-153 510.1 0.0 3e-153 509.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EAU88185.1 - 3.8e-43 147.2 0.0 8.2e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAU88185.1 - 2.4e-15 56.5 0.0 5.2e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EAU88185.1 - 0.00054 19.2 0.0 0.00095 18.5 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EAU88185.1 - 0.0051 15.8 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component adh_short_C2 PF13561.6 EAU88186.2 - 7.4e-55 186.0 0.0 8.4e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU88186.2 - 1.5e-37 129.0 0.1 1.8e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU88186.2 - 1.3e-13 51.3 0.3 1.7e-13 50.9 0.3 1.2 1 0 0 1 1 1 1 KR domain DUF2358 PF10184.9 EAU88187.2 - 0.0018 18.5 0.0 0.0028 17.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EAU88187.2 - 0.0038 17.8 0.0 0.0058 17.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain WD40 PF00400.32 EAU88188.1 - 6.3e-28 96.5 12.4 2.5e-09 37.6 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU88188.1 - 2.6e-08 34.0 0.1 0.033 14.5 0.0 4.6 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU88188.1 - 0.0011 18.0 0.0 0.036 13.0 0.0 2.8 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Sulfate_transp PF00916.20 EAU88189.2 - 1.3e-107 359.8 15.8 1.3e-107 359.8 15.8 1.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 EAU88189.2 - 4.5e-09 36.0 0.0 1.2e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 EAU88189.2 - 0.0069 16.7 0.0 0.019 15.3 0.0 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EAU88189.2 - 0.15 12.5 17.0 0.067 13.6 4.7 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Transcrip_reg PF01709.20 EAU88190.1 - 1.3e-69 234.3 0.6 1.5e-69 234.1 0.6 1.0 1 0 0 1 1 1 1 Transcriptional regulator NYN PF01936.18 EAU88192.2 - 7e-25 88.2 0.0 1.5e-24 87.1 0.0 1.5 2 0 0 2 2 2 1 NYN domain Biotin_lipoyl PF00364.22 EAU88193.2 - 3.6e-09 36.3 0.3 5.3e-09 35.8 0.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EAU88193.2 - 0.0037 17.1 0.0 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like QRPTase_N PF02749.16 EAU88193.2 - 0.065 13.3 0.0 0.17 12.0 0.0 1.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_D23 PF16576.5 EAU88193.2 - 0.12 11.6 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Rad1 PF02144.16 EAU88194.2 - 1.1e-74 251.0 0.0 5.1e-38 130.7 0.0 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Biotin_lipoyl PF00364.22 EAU88195.1 - 2.5e-20 72.1 0.4 4.9e-20 71.1 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EAU88195.1 - 2.1e-09 37.5 1.8 3.8e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EAU88195.1 - 0.0015 18.3 0.0 0.0071 16.1 0.0 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like Sterol-sensing PF12349.8 EAU88196.2 - 4.1e-17 62.4 0.8 1.2e-16 60.9 0.8 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EAU88196.2 - 5.8e-05 21.4 0.3 8.4e-05 20.9 0.3 1.1 1 0 0 1 1 1 1 Patched family ANAPC4_WD40 PF12894.7 EAU88196.2 - 0.03 14.6 0.2 4 7.8 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4255 PF14065.6 EAU88196.2 - 0.052 13.2 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) Hat1_N PF10394.9 EAU88198.2 - 4.4e-54 183.1 0.0 7.9e-54 182.2 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EAU88198.2 - 0.00037 20.7 0.1 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Phage_lysozyme PF00959.19 EAU88198.2 - 0.091 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Phage lysozyme CoA_trans PF01144.23 EAU88199.2 - 2.5e-99 331.1 0.9 7e-59 198.8 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EAU88199.2 - 0.00024 21.0 0.1 0.00066 19.6 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Aldedh PF00171.22 EAU88201.1 - 6.6e-126 420.5 0.0 8.1e-126 420.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SMI1_KNR4 PF09346.10 EAU88202.2 - 5.4e-23 81.8 0.0 1.1e-22 80.9 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Oxidored_FMN PF00724.20 EAU88203.1 - 6.8e-16 58.5 0.0 2.7e-10 40.1 0.0 2.3 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family APH PF01636.23 EAU88204.1 - 6.1e-05 23.1 0.4 0.00093 19.2 0.4 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.29 EAU88205.1 - 2e-44 151.2 0.0 4.7e-44 150.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EAU88205.1 - 1.6e-09 37.5 0.1 1.3e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EAU88205.1 - 1.6e-08 34.6 0.1 5.1e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU88205.1 - 1.3e-07 32.2 0.1 2.7e-05 24.6 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EAU88205.1 - 1.3e-06 28.6 0.2 3.8e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EAU88205.1 - 5.1e-06 25.8 0.0 1.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EAU88205.1 - 0.00015 21.8 0.0 0.0017 18.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EAU88205.1 - 0.00018 22.1 0.0 0.0034 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAU88205.1 - 0.00024 21.4 0.0 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EAU88205.1 - 0.00044 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EAU88205.1 - 0.00058 19.9 0.0 0.0086 16.1 0.1 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAU88205.1 - 0.0008 19.7 3.4 0.012 15.9 0.1 2.9 2 1 1 3 3 2 1 AAA domain AAA_lid_3 PF17862.1 EAU88205.1 - 0.001 18.8 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RNA_helicase PF00910.22 EAU88205.1 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EAU88205.1 - 0.0027 17.0 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 EAU88205.1 - 0.0029 17.4 0.3 0.0083 15.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EAU88205.1 - 0.0035 17.3 0.0 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_7 PF12775.7 EAU88205.1 - 0.0043 16.6 0.1 0.026 14.0 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 EAU88205.1 - 0.0055 16.9 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EAU88205.1 - 0.0057 16.4 0.1 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAU88205.1 - 0.008 15.6 0.1 0.019 14.4 0.1 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EAU88205.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EAU88205.1 - 0.011 15.1 0.3 0.57 9.6 0.0 2.5 3 0 0 3 3 2 0 Bacterial TniB protein NACHT PF05729.12 EAU88205.1 - 0.014 15.3 0.1 0.077 12.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EAU88205.1 - 0.02 14.6 0.1 0.043 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU88205.1 - 0.025 14.2 1.7 0.042 13.4 0.1 2.0 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 EAU88205.1 - 0.045 14.1 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAU88205.1 - 0.056 13.1 0.1 1.1 8.9 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 EAU88205.1 - 0.06 13.1 0.2 0.11 12.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AFG1_ATPase PF03969.16 EAU88205.1 - 0.063 12.1 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase DUF3450 PF11932.8 EAU88205.1 - 0.076 12.3 0.8 0.12 11.7 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATPase_2 PF01637.18 EAU88205.1 - 0.082 12.8 0.4 0.65 9.9 0.0 2.5 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EAU88205.1 - 0.088 13.3 0.2 0.52 10.8 0.1 2.4 2 1 0 2 2 1 0 ABC transporter Bac_DnaA PF00308.18 EAU88205.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 EAU88205.1 - 0.13 11.5 0.8 0.46 9.8 0.0 2.1 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 EAU88205.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 cobW PF02492.19 EAU88205.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.22 EAU88206.2 - 0.0044 16.8 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Xrn1_D3 PF18194.1 EAU88207.2 - 0.21 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 SNRNP27 PF08648.12 EAU88208.2 - 1.5e-29 101.8 0.6 2.7e-29 101.0 0.6 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Rrn6 PF10214.9 EAU88208.2 - 1.5 7.2 8.5 2 6.8 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SUI1 PF01253.22 EAU88209.2 - 2.3e-28 98.5 0.2 3.1e-28 98.1 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.11 EAU88210.1 - 1.2 9.2 20.2 38 4.3 20.2 2.6 1 1 0 1 1 1 0 rRNA processing MIT PF04212.18 EAU88214.2 - 0.0026 17.8 0.1 3.4 7.8 0.0 3.8 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EAU88214.2 - 0.091 12.9 1.4 14 6.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Flu_PA PF00603.17 EAU88214.2 - 0.16 10.0 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA PAP2 PF01569.21 EAU88215.2 - 1.8e-32 112.0 1.1 1.8e-32 112.0 1.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF2339 PF10101.9 EAU88215.2 - 0.097 11.2 2.6 0.085 11.4 0.3 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) PPP4R2 PF09184.11 EAU88216.2 - 7.8e-21 74.9 19.7 6.2e-20 71.9 19.7 2.0 1 1 0 1 1 1 1 PPP4R2 CBS PF00571.28 EAU88216.2 - 0.18 12.3 0.3 0.43 11.1 0.3 1.6 1 0 0 1 1 1 0 CBS domain Parvo_coat PF00740.18 EAU88216.2 - 0.69 8.5 3.2 1 8.0 3.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Spore_III_AF PF09581.10 EAU88216.2 - 1.5 8.8 7.4 2.6 8.0 7.4 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF5327 PF17261.2 EAU88216.2 - 3 8.6 11.7 20 6.0 5.9 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5327) RRN3 PF05327.11 EAU88216.2 - 4 5.9 9.2 5.8 5.3 9.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATP-synt_B PF00430.18 EAU88216.2 - 4.4 7.4 7.1 7.6 6.6 7.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) HhH-GPD PF00730.25 EAU88217.1 - 8.4e-19 68.0 0.0 1.6e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EAU88217.1 - 1.3e-08 34.3 0.0 3.4e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EAU88217.1 - 0.0024 18.1 0.8 0.0053 17.1 0.8 1.6 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Catalase PF00199.19 EAU88218.2 - 1.9e-173 577.0 0.0 3.2e-173 576.2 0.0 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EAU88218.2 - 4.3e-21 74.9 0.1 8.6e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EAU88218.2 - 4.1e-13 49.2 0.1 7.2e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EAU88218.2 - 1.2e-12 48.0 0.1 1.9e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family SPRY PF00622.28 EAU88222.2 - 2e-08 34.4 0.5 4.2e-05 23.7 0.0 3.7 4 0 0 4 4 4 2 SPRY domain DNA_pol_phi PF04931.13 EAU88224.2 - 7.6e-235 781.6 24.8 7.6e-235 781.6 24.8 2.2 2 0 0 2 2 2 1 DNA polymerase phi RasGEF_N PF00618.20 EAU88224.2 - 0.14 12.4 0.4 24 5.2 0.0 3.3 2 0 0 2 2 2 0 RasGEF N-terminal motif MutS_V PF00488.21 EAU88225.2 - 6.6e-68 228.5 0.5 2.1e-67 226.8 0.1 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EAU88225.2 - 3e-36 125.4 0.9 7.1e-36 124.2 0.2 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EAU88225.2 - 2.6e-22 79.2 0.0 5.7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EAU88225.2 - 3.4e-10 40.3 0.0 4e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 MutS domain II Cas_APE2256 PF09651.10 EAU88225.2 - 0.15 12.0 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) ATP12 PF07542.11 EAU88226.1 - 3.6e-42 143.5 0.0 5.7e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Nt_Gln_amidase PF09764.9 EAU88229.2 - 3.7e-36 124.5 0.1 4.1e-36 124.3 0.1 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase UQ_con PF00179.26 EAU88233.1 - 9.5e-35 119.3 0.2 1.1e-34 119.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAU88233.1 - 0.00012 21.8 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAU88233.1 - 0.00041 20.6 0.1 0.00048 20.4 0.1 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EAU88233.1 - 0.0052 16.6 0.1 0.0092 15.8 0.1 1.4 1 0 0 1 1 1 1 UEV domain Glycos_transf_1 PF00534.20 EAU88234.1 - 6.6e-22 77.8 0.0 1.4e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAU88234.1 - 2.4e-13 50.7 0.0 4.6e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EAU88234.1 - 5.4e-07 29.9 0.0 1.2e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 LIP PF03583.14 EAU88234.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase TF_Zn_Ribbon PF08271.12 EAU88235.1 - 0.0042 16.6 1.6 0.0087 15.6 1.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 EAU88235.1 - 0.0056 16.7 0.6 0.039 14.0 0.0 2.6 2 1 1 3 3 3 1 Transcription factor TFIIB repeat CDC45 PF02724.14 EAU88235.1 - 0.86 7.8 6.6 1.2 7.4 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein CAP_N PF01213.19 EAU88236.1 - 6.6e-94 314.9 22.6 3.6e-93 312.5 22.6 2.6 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EAU88236.1 - 6e-60 201.4 6.8 7.8e-60 201.0 6.8 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EAU88236.1 - 0.00051 19.8 4.1 0.00083 19.1 4.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CCDC53 PF10152.9 EAU88236.1 - 0.0051 17.3 0.0 3.9 7.9 0.2 2.6 2 1 0 2 2 2 2 Subunit CCDC53 of WASH complex Mito_fiss_reg PF05308.11 EAU88236.1 - 0.013 15.6 2.6 0.013 15.6 2.6 2.9 2 1 1 3 3 3 0 Mitochondrial fission regulator RF-1 PF00472.20 EAU88237.1 - 6.5e-24 84.1 4.3 6.5e-24 84.1 4.3 1.7 2 0 0 2 2 2 1 RF-1 domain tRNA_int_endo PF01974.17 EAU88239.2 - 8.3e-06 25.8 1.2 1.9e-05 24.6 0.6 1.9 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain Remorin_C PF03763.13 EAU88239.2 - 0.029 14.2 9.3 0.035 14.0 6.7 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region tRNA_int_end_N2 PF12928.7 EAU88239.2 - 0.15 12.3 0.2 0.35 11.1 0.2 1.6 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term CDC27 PF09507.10 EAU88239.2 - 0.53 9.6 11.0 0.71 9.2 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rrn6 PF10214.9 EAU88239.2 - 0.9 7.9 10.2 1.1 7.6 10.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4551 PF15087.6 EAU88239.2 - 3.7 6.3 5.4 4.6 6.0 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Lipase_GDSL_2 PF13472.6 EAU88240.2 - 1.7e-30 106.7 0.0 3.3e-30 105.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU88240.2 - 8.6e-21 74.8 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.20 EAU88241.1 - 8e-13 48.8 0.0 1.5e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Cpn60_TCP1 PF00118.24 EAU88242.1 - 6.1e-149 496.8 13.4 6.9e-149 496.6 13.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 EAU88242.1 - 0.0013 18.3 0.1 0.0038 16.7 0.1 1.8 1 1 0 1 1 1 1 Telomere recombination TPR_1 PF00515.28 EAU88243.2 - 3.5e-28 96.2 12.4 1.5e-07 30.9 0.5 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAU88243.2 - 4.9e-25 85.6 18.2 5e-05 23.1 0.8 8.3 9 0 0 9 9 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU88243.2 - 5.2e-24 84.3 23.8 1.6e-16 60.3 2.4 6.0 4 1 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EAU88243.2 - 2e-19 68.5 12.6 0.012 16.0 0.3 7.5 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EAU88243.2 - 2.9e-18 66.1 18.0 8.7e-05 23.0 0.2 8.2 6 3 2 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 EAU88243.2 - 3.5e-18 64.7 13.2 0.00041 20.9 0.2 7.9 4 2 3 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAU88243.2 - 3.8e-17 62.4 21.3 0.0025 18.1 0.2 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EAU88243.2 - 4.1e-14 52.9 18.8 0.00013 22.5 0.3 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU88243.2 - 5.1e-14 51.2 7.7 0.012 15.7 0.0 6.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAU88243.2 - 2.1e-11 43.3 6.5 0.0014 18.3 0.3 6.9 5 2 2 7 7 7 2 TPR repeat TPR_6 PF13174.6 EAU88243.2 - 9.3e-11 41.7 10.8 0.92 10.3 0.0 7.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAU88243.2 - 2.3e-08 33.5 8.9 0.22 11.6 0.0 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 EAU88243.2 - 0.0003 21.1 1.9 0.54 10.6 0.2 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAU88243.2 - 0.00079 19.5 15.3 0.0029 17.7 0.6 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EAU88243.2 - 0.0023 17.9 0.4 0.06 13.4 0.2 3.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EAU88243.2 - 0.032 14.1 16.0 1.6 8.7 0.2 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat PPTA PF01239.22 EAU88243.2 - 0.077 12.7 0.4 8.6 6.2 0.0 3.2 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.6 EAU88243.2 - 0.38 10.8 9.7 46 4.2 0.1 6.1 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 EAU88243.2 - 0.97 10.2 7.6 13 6.6 0.0 4.3 4 0 0 4 4 4 0 Sel1 repeat TPR_21 PF09976.9 EAU88243.2 - 1.5 8.5 5.2 2.7 7.6 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain SNAP PF14938.6 EAU88243.2 - 2.1 7.7 9.4 0.91 8.9 0.4 3.6 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP TMEM174 PF15029.6 EAU88245.2 - 0.14 11.8 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 PUA PF01472.20 EAU88246.2 - 1.1e-08 34.9 0.1 1.4e-08 34.6 0.1 1.3 1 1 0 1 1 1 1 PUA domain CRM1_C PF08767.11 EAU88247.2 - 1.3e-134 448.4 0.7 1.3e-134 448.4 0.7 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EAU88247.2 - 7.8e-43 146.1 7.0 5.5e-41 140.1 7.4 3.6 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EAU88247.2 - 8.8e-34 115.0 4.0 2.1e-33 113.8 4.0 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EAU88247.2 - 1.6e-30 104.9 1.4 1.6e-30 104.9 1.4 3.2 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EAU88247.2 - 3.7e-19 67.9 2.6 3.7e-19 67.9 2.6 2.7 3 0 0 3 3 3 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EAU88247.2 - 3.1e-14 52.6 0.0 1.1e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EAU88247.2 - 0.027 14.4 0.1 0.46 10.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EAU88247.2 - 0.17 12.5 1.1 7.6 7.2 0.0 3.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region ADH_zinc_N_2 PF13602.6 EAU88249.1 - 1.4e-21 77.9 0.0 2.4e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EAU88249.1 - 6e-14 52.1 0.0 2.3e-13 50.3 0.0 1.8 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU88249.1 - 0.0024 17.7 0.0 0.15 11.9 0.0 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Cutinase PF01083.22 EAU88250.1 - 3.1e-42 144.5 0.0 3.5e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 EAU88250.1 - 1.6e-05 24.8 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.11 EAU88250.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 EAU88250.1 - 0.0098 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) VirJ PF06057.11 EAU88250.1 - 0.036 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.20 EAU88250.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 EAU88250.1 - 0.22 11.3 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_tran_28_C PF04101.16 EAU88251.1 - 1.6e-30 106.3 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 EAU88251.1 - 0.15 10.8 0.0 0.35 9.6 0.0 1.5 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_41 PF13844.6 EAU88251.1 - 0.15 10.5 0.0 8.3 4.7 0.0 2.0 1 1 1 2 2 2 0 Glycosyl transferase family 41 Methyltransf_25 PF13649.6 EAU88252.2 - 0.00052 20.7 0.0 0.00088 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU88252.2 - 0.00073 20.1 0.0 0.0014 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAC PF01849.18 EAU88253.1 - 3.6e-20 71.7 0.0 8.5e-20 70.5 0.0 1.6 2 0 0 2 2 2 1 NAC domain UBA_4 PF14555.6 EAU88253.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain PBP1_TM PF14812.6 EAU88253.1 - 2 8.9 5.5 3.6 8.0 0.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kinesin_assoc PF16183.5 EAU88254.2 - 0.29 11.3 7.4 0.76 9.9 7.4 1.7 1 0 0 1 1 1 0 Kinesin-associated BLOC1_2 PF10046.9 EAU88254.2 - 1.8 8.9 19.9 0.41 11.0 3.8 4.4 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF668 PF05003.12 EAU88254.2 - 2 8.9 4.5 3.4 8.2 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Fib_alpha PF08702.10 EAU88254.2 - 2.9 8.1 20.7 9.7 6.4 6.8 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 EAU88254.2 - 8.5 6.1 10.6 7.1 6.4 0.5 3.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain HSP90 PF00183.18 EAU88255.1 - 2.1e-231 769.3 27.2 2.6e-231 769.0 27.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EAU88255.1 - 5.5e-15 55.8 0.1 1.1e-14 54.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EAU88255.1 - 1.4e-09 37.9 0.1 3.8e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 EAU88255.1 - 0.054 13.5 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN DUF45 PF01863.17 EAU88255.1 - 0.96 9.4 12.8 1.4 8.9 7.5 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 Peptidase_C37 PF05416.12 EAU88255.1 - 2.1 6.8 7.0 3.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Retrotran_gag_2 PF14223.6 EAU88275.2 - 3.7e-09 36.4 0.0 5.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 EAU88275.2 - 8.1e-05 22.2 0.2 0.00017 21.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Rtf2 PF04641.12 EAU88275.2 - 0.34 10.3 11.5 0.53 9.6 11.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.7 EAU88275.2 - 0.77 7.8 8.7 0.98 7.5 8.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 EAU88275.2 - 1.1 8.0 9.0 1.6 7.4 9.0 1.2 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 EAU88275.2 - 2.5 7.9 12.9 4.9 7.0 12.9 1.5 1 0 0 1 1 1 0 Coilin N-terminus HA2 PF04408.23 EAU88277.2 - 5.4e-17 62.0 0.0 1.1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAU88277.2 - 2.1e-15 56.9 0.0 4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAU88277.2 - 2.2e-13 50.5 0.0 6.3e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU88277.2 - 6.2e-07 29.4 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU88277.2 - 3e-06 27.6 0.0 6.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU88277.2 - 0.00071 19.9 0.1 0.0022 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU88277.2 - 0.00082 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EAU88277.2 - 0.015 15.8 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EAU88277.2 - 0.02 15.4 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EAU88277.2 - 0.023 14.7 0.1 0.76 9.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF4096 PF13340.6 EAU88277.2 - 0.026 14.7 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) T2SSE PF00437.20 EAU88277.2 - 0.03 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 EAU88277.2 - 0.054 13.1 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EAU88277.2 - 0.068 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 KaiC TrwB_AAD_bind PF10412.9 EAU88277.2 - 0.17 10.8 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF572 PF04502.13 EAU88278.1 - 6.9e-67 226.4 11.2 7.9e-67 226.2 11.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 EAU88278.1 - 0.0024 17.8 0.8 0.54 10.2 0.1 2.3 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif zf-ACC PF17848.1 EAU88278.1 - 1 9.5 4.4 21 5.3 0.2 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Lar_restr_allev PF14354.6 EAU88278.1 - 2.3 8.7 5.1 0.42 11.0 0.5 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar Mis14 PF08641.12 EAU88279.2 - 3.3e-06 27.4 4.9 6.8e-06 26.4 4.9 1.6 1 0 0 1 1 1 1 Kinetochore protein Mis14 like DUF4559 PF15112.6 EAU88279.2 - 0.055 13.2 2.3 0.078 12.6 2.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) HWE_HK PF07536.14 EAU88279.2 - 0.095 13.4 0.2 0.095 13.4 0.2 2.5 3 0 0 3 3 3 0 HWE histidine kinase SLATT_5 PF18160.1 EAU88279.2 - 0.17 11.2 1.0 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Gar1 PF04410.14 EAU88280.1 - 1.2e-36 125.8 0.0 1.9e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.29 EAU88281.2 - 1.6e-48 164.5 0.0 3.4e-45 153.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU88281.2 - 1.4e-11 44.0 2.8 1.3e-06 28.1 0.2 2.8 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EAU88281.2 - 1.2e-05 25.8 0.0 0.012 16.0 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EAU88281.2 - 0.00012 21.8 0.0 0.0054 16.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 EAU88281.2 - 0.00052 19.9 0.0 0.0093 15.9 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 EAU88281.2 - 0.00056 20.2 0.1 0.052 13.8 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 EAU88281.2 - 0.00095 19.2 0.1 0.026 14.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TsaE PF02367.17 EAU88281.2 - 0.0014 18.7 0.1 0.28 11.2 0.0 3.2 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EAU88281.2 - 0.0016 19.0 0.0 0.018 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EAU88281.2 - 0.003 17.6 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAU88281.2 - 0.0039 17.0 0.0 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.6 EAU88281.2 - 0.004 16.7 0.1 0.027 14.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 EAU88281.2 - 0.0043 16.4 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_2 PF07724.14 EAU88281.2 - 0.0043 17.2 0.0 0.02 15.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EAU88281.2 - 0.0047 16.5 0.0 0.039 13.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EAU88281.2 - 0.0052 17.2 0.0 0.086 13.2 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.26 EAU88281.2 - 0.0074 16.0 0.0 0.83 9.3 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EAU88281.2 - 0.0085 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 EAU88281.2 - 0.0086 15.3 0.0 0.019 14.2 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EAU88281.2 - 0.016 14.6 0.1 0.045 13.1 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EAU88281.2 - 0.036 13.5 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 EAU88281.2 - 0.041 13.8 0.1 0.59 10.0 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EAU88281.2 - 0.098 11.8 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EAU88281.2 - 0.1 12.5 0.0 8 6.3 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.6 EAU88281.2 - 0.16 11.6 0.9 0.25 11.0 0.1 1.7 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 EAU88281.2 - 0.16 11.8 0.0 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 EAU88281.2 - 2.4 8.0 4.2 19 5.1 0.1 3.1 3 0 0 3 3 3 0 NACHT domain PhoD PF09423.10 EAU88282.1 - 4.1e-29 101.7 2.0 1.8e-28 99.6 2.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase DUF1690 PF07956.11 EAU88283.2 - 1.3e-23 84.0 1.9 1.6e-23 83.6 1.9 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Pyrid_oxidase_2 PF13883.6 EAU88283.2 - 0.022 14.7 0.1 0.7 9.8 0.0 2.0 1 1 1 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Metal_resist PF13801.6 EAU88283.2 - 0.039 14.2 2.4 0.077 13.2 2.4 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Glyco_trans_1_2 PF13524.6 EAU88283.2 - 0.52 10.7 3.4 6 7.3 0.0 2.3 1 1 1 2 2 2 0 Glycosyl transferases group 1 TPR_21 PF09976.9 EAU88284.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Myb_Cef PF11831.8 EAU88285.1 - 9.4e-61 205.4 1.0 9.4e-61 205.4 1.0 3.0 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EAU88285.1 - 2.5e-21 75.6 5.5 9.2e-11 41.8 1.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU88285.1 - 5.4e-18 65.0 6.5 3.2e-12 46.5 2.9 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Met_synt_B12 PF02965.17 EAU88285.1 - 0.14 11.6 1.7 0.71 9.3 0.1 2.4 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain XhlA PF10779.9 EAU88285.1 - 0.24 11.6 1.2 3.6 7.8 0.4 3.1 2 0 0 2 2 2 0 Haemolysin XhlA Fungal_trans PF04082.18 EAU88286.2 - 8.2e-10 38.1 0.5 1.7e-09 37.1 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.32 EAU88287.2 - 0.0021 18.8 2.7 0.072 14.0 0.5 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ADK PF00406.22 EAU88288.2 - 5.3e-43 146.7 0.0 1.1e-42 145.6 0.0 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAU88288.2 - 5.3e-31 107.8 0.0 7.9e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAU88288.2 - 3e-08 34.3 0.0 4.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EAU88288.2 - 0.00018 21.2 0.2 0.45 10.2 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EAU88288.2 - 0.00032 20.9 0.0 0.001 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 EAU88288.2 - 0.046 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Aldolase_II PF00596.21 EAU88311.1 - 1.8e-43 148.6 0.0 2.4e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain dsDNA_bind PF01984.20 EAU88312.2 - 2.1e-28 98.8 3.5 2.5e-28 98.6 3.5 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain YjbH PF06082.11 EAU88312.2 - 0.053 12.3 1.1 0.059 12.2 1.1 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4192 PF13830.6 EAU88312.2 - 0.087 12.9 2.9 0.11 12.6 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Cofilin_ADF PF00241.20 EAU88317.2 - 6.8e-24 84.0 0.0 6.3e-16 58.3 0.0 3.1 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Lysine_decarbox PF03641.14 EAU88318.2 - 6.3e-35 120.2 0.1 8.7e-35 119.7 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EAU88318.2 - 1.9e-09 37.3 2.1 3.4e-09 36.5 2.1 1.4 1 0 0 1 1 1 1 SLOG cluster4 family tRNA-synt_1b PF00579.25 EAU88319.1 - 7.3e-22 78.0 0.0 2.3e-21 76.4 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) RRM_1 PF00076.22 EAU88320.2 - 0.0067 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.19 EAU88321.2 - 7.9e-59 199.3 0.0 1.6e-58 198.3 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EAU88321.2 - 1.2e-31 109.3 0.0 2.4e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain HSA PF07529.13 EAU88322.2 - 4.7e-13 49.3 0.6 2.1e-12 47.2 0.6 2.1 1 0 0 1 1 1 1 HSA Myb_DNA-bind_6 PF13921.6 EAU88322.2 - 6e-09 36.0 0.1 1.5e-08 34.7 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EAU88322.2 - 1.2e-08 35.0 0.1 3.3e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cellulase PF00150.18 EAU88323.1 - 8.8e-10 38.5 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 EAU88323.1 - 0.13 12.6 0.0 0.51 10.7 0.0 1.8 2 0 0 2 2 2 0 Radical SAM superfamily DUF515 PF04415.12 EAU88323.1 - 0.24 9.7 0.1 0.35 9.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ETRAMP PF09716.10 EAU88323.1 - 0.27 11.3 0.7 0.45 10.6 0.7 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) IATP PF04568.12 EAU88324.1 - 7.6e-08 32.7 1.8 1e-07 32.3 1.5 1.5 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NmrA PF05368.13 EAU88325.1 - 7.2e-45 153.4 0.0 8.5e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EAU88325.1 - 8.8e-16 58.3 0.0 1.7e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAU88325.1 - 7.8e-06 25.5 0.1 2.3e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAU88325.1 - 0.00017 21.5 0.1 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EAU88325.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAU88325.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EAU88325.1 - 0.02 15.2 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EAU88325.1 - 0.062 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Acetyltransf_13 PF13880.6 EAU88327.1 - 1.5e-19 69.7 0.0 2.5e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EAU88327.1 - 3e-07 30.2 0.7 5e-07 29.4 0.7 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 EAU88327.1 - 3e-05 24.3 0.0 0.0002 21.7 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAU88327.1 - 0.00023 21.1 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU88327.1 - 0.001 19.3 0.0 0.0029 17.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EAU88327.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CDC45 PF02724.14 EAU88329.2 - 1.5e-214 714.0 0.0 1.6e-214 713.9 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Sec_GG PF07549.14 EAU88329.2 - 0.048 13.2 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif Phage_holin_2_1 PF04971.12 EAU88329.2 - 0.22 11.6 1.1 0.43 10.6 0.2 1.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S Scramblase PF03803.15 EAU88330.2 - 7e-26 90.9 0.0 5.6e-22 78.1 0.0 2.0 2 0 0 2 2 2 2 Scramblase GTP_EFTU PF00009.27 EAU88331.2 - 5.5e-31 107.6 1.9 1.5e-29 102.9 1.9 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EAU88331.2 - 2.2e-29 101.7 1.0 2.2e-29 101.7 1.0 2.0 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EAU88331.2 - 3.6e-07 30.3 1.2 6.3e-07 29.5 0.2 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.15 EAU88331.2 - 7.8e-06 25.6 0.0 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Arf PF00025.21 EAU88331.2 - 0.0028 17.1 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.6 EAU88331.2 - 0.011 15.6 6.4 1.1 9.1 0.4 3.0 3 0 0 3 3 3 0 Elongation factor Tu domain 4 PduV-EutP PF10662.9 EAU88331.2 - 0.011 15.5 0.3 0.098 12.4 0.3 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EAU88331.2 - 0.015 14.7 0.1 0.044 13.2 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_26 PF13500.6 EAU88331.2 - 0.018 14.8 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EAU88331.2 - 0.032 14.5 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 EAU88331.2 - 0.4 11.1 5.2 4.2 7.8 0.1 3.4 3 0 0 3 3 3 0 Elongation factor Tu domain 2 CHORD PF04968.12 EAU88332.2 - 1.1e-31 109.3 9.2 1.5e-23 83.3 3.8 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 EAU88332.2 - 0.00026 21.9 0.4 0.00043 21.2 0.4 1.4 1 0 0 1 1 1 1 CS domain Mito_carr PF00153.27 EAU88333.2 - 0.073 13.0 0.0 0.4 10.6 0.0 2.1 2 1 0 2 2 2 0 Mitochondrial carrier protein zf-Mss51 PF13824.6 EAU88336.1 - 7.2e-24 83.6 10.7 1.5e-23 82.6 10.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 EAU88336.1 - 0.086 13.2 5.4 0.17 12.3 5.4 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar IGPD PF00475.18 EAU88337.1 - 3.5e-58 196.0 0.1 5e-58 195.5 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Peptidase_M24 PF00557.24 EAU88339.2 - 2.2e-21 76.5 1.8 2.2e-19 70.0 0.0 2.2 1 1 1 2 2 2 2 Metallopeptidase family M24 MFS_1 PF07690.16 EAU88341.2 - 1.8e-23 83.1 25.5 3.1e-23 82.3 25.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU88341.2 - 2.8e-06 26.5 6.7 1.5e-05 24.0 6.6 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EAU88341.2 - 0.026 12.9 0.2 0.026 12.9 0.2 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ABC2_membrane_4 PF12730.7 EAU88341.2 - 2.6 8.0 12.9 0.03 14.3 2.5 2.8 1 1 1 2 2 2 0 ABC-2 family transporter protein EF-hand_1 PF00036.32 EAU88343.1 - 1.1e-22 77.8 0.1 9.9e-06 24.8 0.0 4.5 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EAU88343.1 - 6.7e-20 69.3 0.6 6e-06 25.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EAU88343.1 - 8.3e-18 63.0 0.0 0.00038 19.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EAU88343.1 - 1.3e-17 64.0 0.1 1.7e-07 31.6 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EAU88343.1 - 1.8e-14 53.3 1.9 1.5e-08 34.3 0.1 3.8 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EAU88343.1 - 0.017 15.5 0.0 21 5.5 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain HHV-5_US34A PF17087.5 EAU88343.1 - 0.021 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus US34A protein family Lambda_tail_I PF06805.12 EAU88343.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I HAD_2 PF13419.6 EAU88345.1 - 2.1e-07 31.2 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU88345.1 - 9.5e-05 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EAU88345.1 - 0.00042 20.6 0.0 0.0021 18.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EAU88345.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.6 1 1 0 1 1 1 0 Acid Phosphatase Ras PF00071.22 EAU88348.2 - 3.7e-65 218.5 0.8 4.3e-65 218.3 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU88348.2 - 1.8e-36 125.0 0.1 2.9e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU88348.2 - 4e-17 62.2 0.2 4.9e-17 61.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAU88348.2 - 1.8e-07 31.2 0.8 0.0023 17.9 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAU88348.2 - 4.2e-06 26.5 0.2 1.1e-05 25.0 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAU88348.2 - 3.7e-05 23.2 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU88348.2 - 4.8e-05 23.4 0.1 8.3e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EAU88348.2 - 5e-05 22.8 0.1 6.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EAU88348.2 - 0.0014 18.2 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 EAU88348.2 - 0.0025 18.3 0.1 0.6 10.5 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU88348.2 - 0.0087 16.5 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 EAU88348.2 - 0.014 15.0 0.0 0.087 12.3 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3873 PF12989.7 EAU88348.2 - 0.026 14.9 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_5 PF07728.14 EAU88348.2 - 0.031 14.3 0.0 0.081 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EAU88348.2 - 0.038 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EAU88348.2 - 0.048 13.9 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EAU88348.2 - 0.06 12.6 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Septin TniB PF05621.11 EAU88348.2 - 0.082 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 EAU88348.2 - 0.089 13.3 0.0 0.14 12.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PRIMA1 PF16101.5 EAU88351.2 - 1.1 9.3 5.9 2.2 8.4 5.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SOR_SNZ PF01680.17 EAU88352.1 - 2.8e-112 373.5 6.3 4e-112 373.0 6.3 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EAU88352.1 - 8.4e-10 38.4 4.8 1.5e-07 31.0 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EAU88352.1 - 7.5e-06 25.2 0.3 0.074 12.1 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 EAU88352.1 - 0.00024 21.1 0.0 0.00059 19.9 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 EAU88352.1 - 0.0022 17.2 0.2 0.16 11.1 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 EAU88352.1 - 0.0065 15.9 5.3 0.085 12.2 0.1 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.21 EAU88352.1 - 0.019 14.2 0.0 0.53 9.4 0.0 2.6 2 1 1 3 3 3 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 EAU88352.1 - 0.024 14.1 0.4 0.52 9.7 0.0 2.4 2 1 0 2 2 2 0 Histidine biosynthesis protein FMN_dh PF01070.18 EAU88352.1 - 0.024 13.6 0.7 0.05 12.6 0.0 1.9 2 1 0 2 2 2 0 FMN-dependent dehydrogenase RNA_pol_Rpc4 PF05132.14 EAU88352.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Img2 PF05046.14 EAU88353.1 - 4.2e-24 84.6 0.0 5e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Piwi PF02171.17 EAU88354.2 - 1.7e-60 204.8 0.0 5.4e-32 111.2 0.0 2.1 2 0 0 2 2 2 2 Piwi domain ArgoL1 PF08699.10 EAU88354.2 - 1e-07 31.5 0.0 3.5e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoN PF16486.5 EAU88354.2 - 6.9e-06 26.7 0.0 1.4e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EAU88354.2 - 3e-05 24.3 0.1 9.8e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 EAU88354.2 - 0.00013 21.8 0.5 0.00034 20.4 0.0 1.9 2 0 0 2 2 2 1 PAZ domain DUF1708 PF08101.11 EAU88356.2 - 9e-22 77.8 0.3 1.2e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 EAU88356.2 - 0.00015 21.6 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Hamartin PF04388.12 EAU88356.2 - 0.23 10.1 0.0 0.23 10.1 0.0 3.1 2 1 1 3 3 3 0 Hamartin protein stn_TNFRSF12A PF12191.8 EAU88357.2 - 0.083 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PetG PF02529.15 EAU88357.2 - 0.27 11.1 1.4 0.46 10.4 1.4 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 HAGH_C PF16123.5 EAU88359.2 - 4.3e-19 68.8 0.0 1e-18 67.6 0.0 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EAU88359.2 - 9.8e-12 45.3 1.5 3.7e-11 43.4 1.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EAU88359.2 - 0.00014 21.5 0.2 0.00071 19.2 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Got1 PF04178.12 EAU88360.1 - 7.9e-28 97.1 20.4 1e-27 96.8 20.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Rad21_Rec8 PF04824.16 EAU88361.2 - 9.3e-13 47.3 0.0 1.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF445 PF04286.12 EAU88362.2 - 0.17 11.7 6.6 0.34 10.7 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CelTOS PF18659.1 EAU88362.2 - 2.4 8.6 5.2 11 6.5 4.2 2.3 1 1 1 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites PPTA PF01239.22 EAU88364.2 - 5.3e-43 143.6 17.9 6.5e-11 41.6 0.6 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Telomere_reg-2 PF10193.9 EAU88364.2 - 0.046 14.2 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Telomere length regulation protein TPR_14 PF13428.6 EAU88365.2 - 2.5e-11 43.4 20.3 1.6 9.8 0.0 11.6 10 3 2 12 12 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAU88365.2 - 1.3e-05 25.6 12.4 1.5 9.3 0.1 6.6 5 1 0 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 EAU88365.2 - 2.8e-05 24.2 12.5 0.016 15.2 0.3 5.4 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 EAU88365.2 - 0.00017 21.5 11.2 1.3 9.0 0.2 7.4 8 0 0 8 8 8 1 Mad3/BUB1 homology region 1 TPR_7 PF13176.6 EAU88365.2 - 0.00062 19.6 1.2 2.4 8.4 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU88365.2 - 0.00078 19.7 10.3 11 6.4 0.1 7.0 6 1 2 8 8 7 0 Tetratricopeptide repeat MIT PF04212.18 EAU88365.2 - 0.0092 16.0 2.1 2.6 8.2 0.0 4.8 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EAU88365.2 - 0.017 15.2 0.1 0.24 11.6 0.0 8.5 11 0 0 11 11 9 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EAU88365.2 - 0.058 12.5 0.1 0.058 12.5 0.1 5.0 2 2 3 5 5 5 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 EAU88365.2 - 0.1 13.0 14.2 23 5.7 0.0 7.4 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU88365.2 - 0.11 12.4 7.8 4 7.4 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat HAT PF02184.16 EAU88365.2 - 0.21 11.6 6.6 2.7 8.1 0.1 5.5 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_8 PF13181.6 EAU88365.2 - 0.26 11.6 20.7 21 5.7 0.0 8.8 10 1 0 10 10 9 0 Tetratricopeptide repeat GEN1_C PF18380.1 EAU88365.2 - 0.3 12.0 3.2 1.4 9.8 0.4 3.3 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain TPR_4 PF07721.14 EAU88365.2 - 0.51 11.1 0.0 0.51 11.1 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat AATF-Che1 PF13339.6 EAU88365.2 - 1.3 9.8 4.2 21 5.8 0.0 4.1 4 1 0 4 4 3 0 Apoptosis antagonizing transcription factor PSII_Pbs27 PF13326.6 EAU88365.2 - 1.9 8.8 5.2 2.5 8.4 0.2 2.8 2 0 0 2 2 2 0 Photosystem II Pbs27 Syntaxin-6_N PF09177.11 EAU88366.1 - 0.011 16.2 0.3 2.2 8.9 0.0 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CK2S PF15011.6 EAU88366.1 - 0.17 11.8 0.8 0.57 10.1 0.1 2.0 2 1 0 3 3 3 0 Casein Kinase 2 substrate DUF148 PF02520.17 EAU88366.1 - 0.2 11.8 2.1 11 6.1 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 Brix PF04427.18 EAU88367.1 - 3.6e-45 154.5 0.0 4.8e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain Nop25 PF09805.9 EAU88367.1 - 0.79 10.2 22.4 1.7 9.1 22.4 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Dicty_REP PF05086.12 EAU88367.1 - 2.1 6.2 6.6 2.9 5.8 6.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM214 PF10151.9 EAU88367.1 - 7 5.0 7.4 10 4.4 7.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator SDA1 PF05285.12 EAU88367.1 - 7.2 5.9 26.5 12 5.2 26.5 1.3 1 0 0 1 1 1 0 SDA1 Cyto_heme_lyase PF01265.17 EAU88368.2 - 4.7e-46 157.7 15.0 5.2e-44 151.0 15.0 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase NMO PF03060.15 EAU88369.1 - 5.8e-50 170.6 1.4 9.6e-50 169.8 1.4 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EAU88369.1 - 1.3e-08 34.3 2.4 5.3e-07 29.0 2.4 2.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAU88369.1 - 0.00018 20.6 3.4 0.00018 20.6 3.4 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DUF3445 PF11927.8 EAU88370.2 - 1.5e-72 243.8 0.0 1.9e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) WD40 PF00400.32 EAU88371.2 - 2.9e-10 40.5 0.6 0.00029 21.6 0.3 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 EAU88371.2 - 0.0055 15.4 0.0 0.0063 15.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Peptidase_C97 PF05903.14 EAU88372.1 - 1.4e-40 138.6 0.0 2.1e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 EAU88372.1 - 2.9e-38 131.7 0.1 4.3e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 EAU88372.1 - 1.5e-14 53.8 0.0 3.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAU88372.1 - 6.6e-07 29.8 0.1 4.3e-06 27.1 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain TraF PF13728.6 EAU88372.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 EAU88372.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 EAU88372.1 - 0.14 12.3 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Endonuclease_NS PF01223.23 EAU88376.2 - 1.8e-55 188.2 0.0 2.5e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Not1 PF04054.15 EAU88377.2 - 1.2e-129 432.5 0.0 2.2e-129 431.6 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EAU88377.2 - 1.6e-95 318.8 0.7 4.7e-95 317.3 0.7 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain Sugar_tr PF00083.24 EAU88377.2 - 1.4e-55 189.0 11.6 1.5e-44 152.6 0.4 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter DUF3819 PF12842.7 EAU88377.2 - 2.7e-54 183.1 1.5 5e-54 182.2 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EAU88377.2 - 1.3e-51 174.5 0.0 3.3e-51 173.2 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EAU88377.2 - 3.6e-44 150.5 1.3 8.4e-44 149.3 1.3 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat MFS_1 PF07690.16 EAU88377.2 - 6.8e-12 45.0 28.7 9e-07 28.1 6.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.8 EAU88377.2 - 0.1 12.9 0.1 0.51 10.6 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Alpha-amylase PF00128.24 EAU88378.2 - 5.6e-51 174.1 0.2 5.1e-49 167.6 0.2 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EAU88378.2 - 6.8e-12 45.5 0.2 1.5e-11 44.4 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 EAU88378.2 - 0.021 13.9 0.2 0.044 12.9 0.0 1.5 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain JIP_LZII PF16471.5 EAU88378.2 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Tubulin PF00091.25 EAU88379.2 - 9e-71 238.1 0.0 5.3e-70 235.6 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EAU88379.2 - 2.4e-46 157.0 0.1 5e-46 156.0 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EAU88379.2 - 0.0013 19.0 0.0 0.0065 16.8 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EAU88379.2 - 0.0027 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EAU88379.2 - 0.012 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Hrs_helical PF12210.8 EAU88379.2 - 0.033 14.7 0.2 0.075 13.6 0.2 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Senescence PF06911.12 EAU88380.1 - 3.8e-58 196.8 0.2 5.6e-58 196.3 0.2 1.3 1 0 0 1 1 1 1 Senescence-associated protein MBF1 PF08523.10 EAU88381.2 - 1.2e-27 96.2 2.9 2.2e-27 95.3 2.9 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EAU88381.2 - 1.4e-14 53.9 0.1 2.3e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EAU88381.2 - 5.4e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EAU88381.2 - 0.0014 18.6 0.0 0.0037 17.3 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.6 EAU88381.2 - 0.0055 16.5 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HCNGP PF07818.13 EAU88381.2 - 0.12 13.1 0.0 0.19 12.4 0.0 1.4 1 0 0 1 1 1 0 HCNGP-like protein p53-inducible11 PF14936.6 EAU88382.1 - 3.1 7.8 12.6 0.35 10.9 7.7 1.8 2 1 1 3 3 3 0 Tumour protein p53-inducible protein 11 Tetraspanin PF00335.20 EAU88382.1 - 3.2 7.4 16.5 7.2 6.2 16.5 1.7 1 1 0 1 1 1 0 Tetraspanin family DUF805 PF05656.14 EAU88382.1 - 5.6 7.4 10.9 66 4.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Bmt2 PF11968.8 EAU88383.1 - 3.2e-65 220.0 0.0 3.9e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EAU88383.1 - 0.00082 19.2 0.0 0.0015 18.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Spt4 PF06093.13 EAU88384.1 - 4.6e-31 106.7 0.1 5.6e-31 106.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger T2SSJ PF11612.8 EAU88384.1 - 0.047 13.9 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein J 5_nucleotid_C PF02872.18 EAU88385.1 - 1.9e-27 96.4 0.0 4.7e-27 95.2 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EAU88385.1 - 1.3e-06 29.0 0.1 2.5e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PAP2_3 PF14378.6 EAU88386.2 - 0.046 13.4 0.5 0.063 13.0 0.5 1.4 1 1 0 1 1 1 0 PAP2 superfamily SH2 PF00017.24 EAU88386.2 - 0.048 13.8 0.0 0.09 12.9 0.0 1.4 1 0 0 1 1 1 0 SH2 domain DUF2420 PF10336.9 EAU88387.2 - 3.4e-08 33.5 0.2 7.7e-08 32.3 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2420) RNA_pol_Rpc82 PF05645.13 EAU88388.2 - 7.7e-18 65.2 0.5 7.7e-18 65.2 0.5 2.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 EAU88388.2 - 2.9e-08 33.5 0.0 3.6e-06 26.8 0.0 3.0 2 1 0 2 2 2 1 TFIIE alpha subunit HTH_9 PF08221.11 EAU88388.2 - 2.8e-05 24.1 0.3 0.23 11.6 0.0 3.7 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TetR_C_20 PF17925.1 EAU88388.2 - 0.14 12.5 0.9 22 5.4 0.0 2.8 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain SPT16 PF08644.11 EAU88389.2 - 1.2e-56 191.1 0.2 1.2e-56 191.1 0.2 2.2 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EAU88389.2 - 3.8e-38 130.8 0.4 1.4e-37 129.0 0.0 2.3 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EAU88389.2 - 2.5e-22 79.6 0.0 5.2e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EAU88389.2 - 3.3e-15 56.3 0.6 6.4e-14 52.1 0.0 2.7 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 EAU88389.2 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) YL1 PF05764.13 EAU88389.2 - 5.6 7.0 36.9 0.43 10.6 16.8 3.7 4 0 0 4 4 4 0 YL1 nuclear protein DUF2834 PF11196.8 EAU88390.1 - 0.0082 16.5 13.0 0.089 13.2 0.4 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF2834) DEAD PF00270.29 EAU88392.2 - 4.2e-25 88.5 0.0 7.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EAU88392.2 - 1.1e-14 54.9 3.0 4.2e-14 53.1 3.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EAU88392.2 - 4.6e-14 52.7 0.1 1.1e-11 45.1 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EAU88392.2 - 1.7e-07 31.4 0.1 3.1e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EAU88392.2 - 0.0026 18.1 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like Pkinase PF00069.25 EAU88393.1 - 8.9e-23 81.0 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU88393.1 - 1.3e-13 50.9 0.0 2.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase PF01425.21 EAU88393.1 - 0.12 11.3 4.9 0.19 10.7 4.9 1.3 1 0 0 1 1 1 0 Amidase Hydrophobin PF01185.18 EAU88395.2 - 4.5e-07 30.4 1.6 5.9e-07 30.0 1.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NAD_binding_2 PF03446.15 EAU88397.1 - 2.9e-38 131.5 0.0 4.2e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EAU88397.1 - 7.9e-30 103.6 0.0 1.5e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EAU88397.1 - 0.019 15.5 0.2 0.049 14.2 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EAU88397.1 - 0.099 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 EAU88398.2 - 0.0014 18.1 0.1 0.0024 17.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cytochrom_B561 PF03188.16 EAU88399.2 - 4.1e-11 43.2 4.6 4.1e-11 43.2 4.6 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF5305 PF17231.2 EAU88399.2 - 0.044 13.2 1.0 0.056 12.9 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF4271 PF14093.6 EAU88399.2 - 0.17 11.8 5.1 0.18 11.7 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) SPDY PF03771.16 EAU88399.2 - 0.19 11.7 1.8 1.9 8.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Sec7 PF01369.20 EAU88400.2 - 1.2e-67 227.2 0.1 2.1e-67 226.4 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EAU88400.2 - 1.5e-18 67.2 1.1 8.4e-17 61.5 0.0 3.2 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EAU88400.2 - 0.02 14.7 2.2 0.91 9.4 0.1 4.5 6 0 0 6 6 6 0 Domain of unknown function (DUF1981) IstB_IS21 PF01695.17 EAU88400.2 - 0.039 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Lin-8 PF03353.15 EAU88400.2 - 0.88 9.1 7.7 1.5 8.3 7.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Proteasome PF00227.26 EAU88401.2 - 9.6e-61 204.6 0.0 1.4e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAU88401.2 - 6.5e-09 35.3 0.2 2.9e-08 33.2 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.13 EAU88402.2 - 1e-41 142.7 0.0 4.8e-41 140.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family C78 MAT1 PF06391.13 EAU88403.2 - 1.9e-57 194.4 17.7 2.4e-57 194.1 17.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 U79_P34 PF03064.16 EAU88403.2 - 3.3 7.0 9.5 5.4 6.3 9.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.14 EAU88403.2 - 6.2 5.0 10.1 7.8 4.7 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoporin_FG PF13634.6 EAU88404.2 - 4.6e-06 27.4 6.1 4.6e-06 27.4 6.1 10.0 4 2 5 9 9 9 3 Nucleoporin FG repeat region bMG5 PF17972.1 EAU88404.2 - 0.019 15.3 3.6 0.073 13.4 0.6 3.4 3 0 0 3 3 3 0 Bacterial Alpha-2-macroglobulin MG5 domain DUF974 PF06159.13 EAU88405.2 - 6.9e-79 265.1 0.0 9.1e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) V-ATPase_H_N PF03224.14 EAU88406.1 - 1.5e-76 257.7 0.8 2e-47 162.1 0.1 2.6 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 EAU88406.1 - 1.7e-46 157.2 0.2 2.7e-45 153.2 0.1 2.3 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.13 EAU88406.1 - 2e-05 24.2 0.3 4.1e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Armadillo-like Arm PF00514.23 EAU88406.1 - 8.5e-05 22.5 0.4 23 5.2 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EAU88406.1 - 0.00016 21.7 0.2 0.13 12.6 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EAU88406.1 - 0.00063 20.1 0.0 0.0073 16.7 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats DUF1779 PF08680.10 EAU88406.1 - 0.082 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 TATA-box binding MRP-L46 PF11788.8 EAU88407.1 - 4.9e-18 66.0 0.2 1.2e-17 64.8 0.1 1.7 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EAU88407.1 - 5.8e-09 36.1 0.2 2e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain Abhydrolase_1 PF00561.20 EAU88408.2 - 0.00079 19.1 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAU88408.2 - 0.0013 18.0 0.1 0.0029 16.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU88408.2 - 0.0059 17.2 3.4 0.015 15.9 3.4 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EAU88408.2 - 0.015 14.9 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Striatin PF08232.12 EAU88410.2 - 2.5e-51 174.3 0.0 2.5e-51 174.3 0.0 2.6 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 EAU88410.2 - 1.2e-39 133.6 4.4 1.3e-06 29.0 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU88410.2 - 5.8e-10 39.3 0.0 0.18 12.1 0.0 5.1 3 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 EAU88410.2 - 0.013 15.5 15.4 0.12 12.3 3.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nucleoporin_N PF08801.11 EAU88410.2 - 0.019 13.7 0.0 0.093 11.5 0.0 2.1 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 EAU88410.2 - 0.1 11.2 0.1 23 3.5 0.0 3.5 3 1 1 4 4 4 0 Nucleoporin Nup120/160 DUF4852 PF16144.5 EAU88410.2 - 0.13 12.4 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) DUF4482 PF14818.6 EAU88410.2 - 6 7.7 11.8 0.38 11.6 5.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) PDEase_II PF02112.15 EAU88411.1 - 5.4e-49 167.1 0.0 1.2e-48 165.9 0.0 1.5 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EAU88411.1 - 6.9e-07 29.0 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Dicty_REP PF05086.12 EAU88412.2 - 0.47 8.4 3.8 0.63 7.9 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein EF-hand_4 PF12763.7 EAU88413.1 - 2.2e-32 111.1 0.0 2.1e-12 46.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EAU88413.1 - 9e-07 29.3 0.0 0.013 15.9 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair UBA PF00627.31 EAU88413.1 - 3.5e-06 26.8 0.0 7.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 EAU88413.1 - 0.00016 21.0 2.1 7.6 6.3 0.0 4.9 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 EAU88413.1 - 0.0018 18.0 2.8 13 6.1 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain MOR2-PAG1_mid PF14228.6 EAU88413.1 - 0.13 9.9 0.1 0.18 9.4 0.1 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region UBA_3 PF09288.10 EAU88413.1 - 0.13 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain EF-hand_8 PF13833.6 EAU88413.1 - 0.15 11.9 0.1 2.6 8.0 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair TPR_MLP1_2 PF07926.12 EAU88413.1 - 1.6 8.8 42.0 1.1 9.3 16.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EAU88413.1 - 5.3 5.8 38.9 3.4 6.5 21.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein UQ_con PF00179.26 EAU88414.2 - 4.1e-42 143.1 0.0 5e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAU88414.2 - 6.4e-05 23.2 0.0 7.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EAU88414.2 - 0.003 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B R3H PF01424.22 EAU88415.1 - 4.7e-11 42.5 0.0 1.2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EAU88415.1 - 1.5e-07 31.1 0.0 3.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LigB PF02900.18 EAU88416.1 - 6.4e-31 107.4 0.0 8.6e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF4910 PF16254.5 EAU88416.1 - 0.067 12.1 0.0 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4910) Pkinase PF00069.25 EAU88417.2 - 3.9e-67 226.4 0.0 5e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU88417.2 - 5e-31 107.9 0.0 6.9e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU88417.2 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RTC PF01137.21 EAU88418.1 - 6.9e-82 273.9 0.0 7.9e-82 273.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EAU88418.1 - 1.5e-27 96.1 0.1 3.1e-27 95.1 0.1 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF4888 PF16229.5 EAU88418.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) CDC50 PF03381.15 EAU88419.1 - 4.4e-91 305.3 0.0 5.7e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family MCM_bind PF09739.9 EAU88420.2 - 7.1e-44 150.2 0.1 8.7e-42 143.3 0.0 2.8 1 1 2 3 3 3 3 Mini-chromosome maintenance replisome factor DUF5427 PF10310.9 EAU88420.2 - 0.034 13.1 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PHD PF00628.29 EAU88421.2 - 1.7e-16 59.8 16.5 1.9e-10 40.4 5.4 2.6 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 EAU88421.2 - 0.00063 19.4 0.9 0.042 13.5 0.5 2.7 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EAU88421.2 - 0.0011 18.5 8.3 0.061 12.9 0.5 3.0 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 EAU88421.2 - 0.0014 18.5 1.1 0.34 10.8 0.0 2.7 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 EAU88421.2 - 0.012 15.8 0.4 0.012 15.8 0.4 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EAU88421.2 - 0.078 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain PGM_PMM_I PF02878.16 EAU88422.2 - 2.8e-39 134.0 0.0 7.2e-39 132.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EAU88422.2 - 1.3e-18 67.5 0.0 2.7e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EAU88422.2 - 6e-18 65.1 0.0 9.8e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EAU88422.2 - 2.4e-05 24.4 0.0 7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain TMEM187 PF15100.6 EAU88422.2 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM187 protein family PRP38 PF03371.15 EAU88423.2 - 1.1e-60 204.5 0.8 1.3e-60 204.2 0.8 1.1 1 0 0 1 1 1 1 PRP38 family HEAT_2 PF13646.6 EAU88423.2 - 0.081 13.3 0.1 0.17 12.3 0.0 1.6 2 0 0 2 2 2 0 HEAT repeats RSRP PF17069.5 EAU88423.2 - 0.53 9.8 62.3 0.87 9.1 62.3 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Ribosomal_L27A PF00828.19 EAU88424.1 - 4e-38 131.0 0.0 5.7e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3653 PF12375.8 EAU88424.1 - 0.12 12.5 0.6 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 Phage protein IPPT PF01715.17 EAU88425.2 - 2.5e-57 194.3 0.0 7.8e-57 192.7 0.0 1.8 2 1 0 2 2 2 1 IPP transferase IPT PF01745.16 EAU88425.2 - 6.3e-05 22.5 0.1 0.023 14.1 0.0 2.4 2 0 0 2 2 2 2 Isopentenyl transferase AAA_25 PF13481.6 EAU88425.2 - 0.015 14.9 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU88425.2 - 0.018 15.3 0.0 0.11 12.8 0.0 2.1 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EAU88425.2 - 0.024 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EAU88425.2 - 0.036 14.6 0.0 0.096 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EAU88425.2 - 0.087 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EAU88425.2 - 0.11 12.9 0.0 0.84 10.0 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain Fasciclin PF02469.22 EAU88426.1 - 9.8e-34 116.3 3.2 6.9e-21 74.8 0.0 3.8 3 1 0 3 3 3 3 Fasciclin domain ATP-synt_ab PF00006.25 EAU88427.1 - 2.2e-108 360.8 0.0 3e-108 360.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EAU88427.1 - 9.8e-44 148.1 0.0 1.8e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EAU88427.1 - 2.2e-14 53.7 5.0 5.6e-14 52.4 5.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Zn_clus PF00172.18 EAU88431.2 - 0.00061 19.9 17.0 0.00095 19.2 17.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ING PF12998.7 EAU88434.1 - 2.3e-11 44.2 0.7 5.3e-10 39.8 0.5 2.3 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EAU88434.1 - 1.4e-06 28.1 6.1 2.7e-06 27.2 6.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EAU88434.1 - 0.0012 18.3 0.5 0.0027 17.2 0.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EAU88434.1 - 0.038 14.2 0.1 0.086 13.1 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF1759 PF03564.15 EAU88434.1 - 0.088 12.7 0.5 3.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Anophelin PF10731.9 EAU88434.1 - 0.18 11.6 0.8 0.35 10.8 0.8 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito BBS1 PF14779.6 EAU88434.1 - 0.2 11.1 0.4 0.37 10.2 0.4 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DEAD PF00270.29 EAU88435.1 - 3.5e-46 157.2 0.0 1e-45 155.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU88435.1 - 7.6e-27 93.9 0.0 4.1e-26 91.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU88435.1 - 1.4e-05 25.2 0.0 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EAU88435.1 - 0.25 10.6 6.2 0.99 8.7 0.0 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Asp-B-Hydro_N PF05279.11 EAU88435.1 - 2.5 8.1 12.1 4.4 7.3 12.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PNK3P PF08645.11 EAU88436.2 - 1.4e-47 161.4 0.0 2.5e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EAU88436.2 - 1.2e-19 70.9 0.2 3.4e-17 62.9 0.2 2.6 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 EAU88436.2 - 0.00057 19.4 1.8 0.17 11.3 1.8 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Hydrolase_6 PF13344.6 EAU88436.2 - 0.031 14.4 0.0 0.85 9.8 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.12 EAU88436.2 - 0.056 12.7 0.0 2.7 7.2 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EAU88436.2 - 0.066 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase RNA_pol_N PF01194.17 EAU88436.2 - 0.12 12.7 0.0 0.57 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA polymerases N / 8 kDa subunit AAA_16 PF13191.6 EAU88436.2 - 0.2 12.0 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NUDIX PF00293.28 EAU88437.2 - 3e-14 53.2 0.0 7.7e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain SDA1 PF05285.12 EAU88438.1 - 4.6e-85 286.1 38.0 3.8e-46 158.1 13.6 4.2 3 1 1 4 4 4 3 SDA1 NUC130_3NT PF08158.12 EAU88438.1 - 1.3e-21 76.6 1.8 1.7e-19 69.9 0.1 2.7 2 0 0 2 2 2 2 NUC130/3NT domain PGA2 PF07543.12 EAU88438.1 - 0.005 16.8 3.6 0.005 16.8 3.6 4.0 4 1 0 4 4 4 1 Protein trafficking PGA2 YL1 PF05764.13 EAU88438.1 - 0.4 10.8 51.6 0.13 12.4 3.8 3.4 3 0 0 3 3 3 0 YL1 nuclear protein SUA5 PF03481.13 EAU88438.1 - 1.9 9.0 6.8 0.19 12.3 0.3 2.7 3 0 0 3 3 3 0 Putative GTP-binding controlling metal-binding PGK PF00162.19 EAU88439.2 - 5.8e-151 502.7 0.5 6.6e-151 502.6 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase JHD PF17811.1 EAU88440.2 - 9.4e-12 45.4 0.0 2.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 EAU88440.2 - 9.4e-10 38.9 0.3 3.2e-09 37.2 0.3 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EAU88440.2 - 1e-07 31.7 10.0 1.9e-07 30.9 10.0 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 EAU88440.2 - 5.9e-05 22.9 0.2 0.00075 19.3 0.2 2.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 EAU88440.2 - 0.031 13.9 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF4451 PF14616.6 EAU88440.2 - 0.054 13.7 2.7 0.45 10.7 2.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) PHD_2 PF13831.6 EAU88440.2 - 0.1 12.2 4.2 0.21 11.2 4.2 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EAU88440.2 - 0.12 12.3 2.4 0.24 11.4 2.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 EAU88440.2 - 0.17 12.2 2.1 0.38 11.1 2.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Lar_restr_allev PF14354.6 EAU88440.2 - 0.25 11.8 5.6 0.67 10.4 5.6 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Sel1 PF08238.12 EAU88441.1 - 2e-51 171.3 26.8 1.4e-09 38.3 0.0 7.6 7 0 0 7 7 7 7 Sel1 repeat ANAPC3 PF12895.7 EAU88441.1 - 1.5 9.1 11.2 1.3 9.3 1.7 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EAU88441.1 - 7.1 7.7 18.3 8.3 7.5 0.8 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat USP7_ICP0_bdg PF12436.8 EAU88443.2 - 5.4e-87 291.1 0.2 4.5e-86 288.1 0.0 2.4 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EAU88443.2 - 7.3e-70 234.9 3.0 2.7e-66 223.2 0.3 2.7 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 EAU88443.2 - 1.4e-50 172.2 0.2 2.4e-50 171.4 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAU88443.2 - 7.8e-23 81.6 0.0 2.2e-22 80.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EAU88443.2 - 9.9e-07 28.9 0.0 4.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 MATH domain ubiquitin PF00240.23 EAU88443.2 - 0.0071 16.1 0.1 1.2 8.9 0.0 4.0 4 0 0 4 4 4 1 Ubiquitin family Sec66 PF09802.9 EAU88444.1 - 9.8e-57 191.4 0.1 1.2e-56 191.2 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4743 PF15916.5 EAU88445.1 - 7.4e-09 35.6 0.0 1.3e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EAU88445.1 - 3e-06 27.3 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1176 PF06674.11 EAU88445.1 - 0.24 10.8 0.0 0.34 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Citrate_synt PF00285.21 EAU88446.1 - 6.1e-99 331.5 0.0 7.4e-99 331.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain B56 PF01603.20 EAU88448.2 - 8.7e-184 611.3 8.0 2.1e-175 583.7 3.9 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EAU88448.2 - 0.0016 18.3 2.8 0.44 10.4 0.2 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal CAP_N PF01213.19 EAU88448.2 - 0.71 9.3 10.1 11 5.4 7.9 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EAU88448.2 - 6.9 6.7 9.5 11 6.1 4.2 2.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Methyltr_RsmB-F PF01189.17 EAU88451.2 - 6.9e-77 257.6 0.0 9.7e-77 257.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 EAU88451.2 - 0.00075 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EAU88451.2 - 0.0034 17.2 0.0 0.008 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 EAU88451.2 - 0.018 15.5 1.7 0.68 10.5 0.9 3.2 2 1 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF DUF938 PF06080.12 EAU88451.2 - 0.033 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 EAU88451.2 - 0.1 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EAU88451.2 - 0.11 13.2 0.0 0.31 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SUR7 PF06687.12 EAU88452.1 - 4.2e-19 69.0 9.9 6.5e-19 68.4 9.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family W2 PF02020.18 EAU88454.1 - 9e-11 41.8 0.0 9e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 EAU88454.1 - 8e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EAU88454.1 - 3.6e-07 29.6 13.6 0.00045 19.8 5.5 4.0 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EAU88454.1 - 0.00032 19.8 0.3 0.00074 18.6 0.2 1.6 2 0 0 2 2 2 1 L-fucokinase NTP_transf_3 PF12804.7 EAU88454.1 - 0.00061 20.2 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EAU88454.1 - 0.0017 18.0 13.7 0.0034 17.1 1.4 3.8 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EAU88454.1 - 0.13 10.3 3.7 0.26 9.4 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Abhydrolase_3 PF07859.13 EAU88455.1 - 2.9e-11 43.6 0.0 4.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU88455.1 - 1.4e-05 25.8 2.6 1.9e-05 25.4 2.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 EAU88455.1 - 0.0028 16.6 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EAU88455.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase Aminotran_5 PF00266.19 EAU88456.2 - 2.4e-09 36.6 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DUF3035 PF11233.8 EAU88456.2 - 0.18 12.1 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) FAD_binding_3 PF01494.19 EAU88457.2 - 8.5e-18 64.7 0.0 3.8e-09 36.3 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain DAO PF01266.24 EAU88457.2 - 8.7e-08 32.1 0.0 5.6e-06 26.2 0.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU88457.2 - 1.2e-05 25.5 0.5 4.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU88457.2 - 4.5e-05 22.8 0.0 7.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU88457.2 - 0.00081 19.9 0.0 0.0054 17.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU88457.2 - 0.01 14.6 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EAU88457.2 - 0.012 14.7 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 EAU88457.2 - 0.015 14.8 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 EAU88457.2 - 0.026 13.6 0.1 0.05 12.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 EAU88457.2 - 0.029 14.0 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 EAU88457.2 - 0.041 13.0 0.1 0.079 12.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 EAU88457.2 - 0.12 11.4 0.2 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase AT_hook PF02178.19 EAU88458.1 - 0.00024 20.6 60.8 0.13 12.2 8.7 4.9 5 0 0 5 5 5 4 AT hook motif Pol_alpha_B_N PF08418.10 EAU88458.1 - 2.5 8.0 5.9 2.8 7.8 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PRKCSH PF07915.13 EAU88459.2 - 1.8e-14 54.5 1.9 2.6e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pkinase PF00069.25 EAU88460.2 - 1e-44 152.9 0.0 2.9e-44 151.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU88460.2 - 1.2e-25 90.2 0.0 2e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAU88460.2 - 0.0049 16.8 0.2 0.016 15.1 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DEAD PF00270.29 EAU88461.1 - 9.2e-50 168.8 0.1 1e-48 165.4 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU88461.1 - 2.5e-27 95.4 0.0 1.8e-26 92.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EAU88461.1 - 7e-05 21.7 0.0 7.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EAU88461.1 - 0.0001 22.4 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_16 PF10294.9 EAU88462.1 - 4.9e-18 65.5 0.0 4.7e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EAU88462.1 - 0.0018 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAU88462.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Asn_synthase PF00733.21 EAU88464.1 - 2.5e-90 303.7 0.1 3.2e-57 194.8 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EAU88464.1 - 1.2e-34 118.9 0.0 1.8e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EAU88464.1 - 1.1e-28 100.0 0.0 2.4e-28 99.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EAU88464.1 - 0.0021 17.5 0.0 0.0057 16.1 0.0 1.7 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.13 EAU88464.1 - 0.0034 16.9 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 EAU88464.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Syntaxin PF00804.25 EAU88465.2 - 1.5e-23 83.5 10.3 6.3e-22 78.2 10.3 2.2 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 EAU88465.2 - 0.0037 17.6 1.6 0.0037 17.6 1.6 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Flu_M1_C PF08289.11 EAU88465.2 - 0.064 13.5 0.2 1.8 8.8 0.0 2.4 1 1 1 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain MCPsignal PF00015.21 EAU88465.2 - 0.26 11.1 5.8 0.95 9.3 0.5 2.3 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA1 PF07160.12 EAU88465.2 - 0.27 11.1 6.0 0.95 9.3 0.5 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Spectrin PF00435.21 EAU88465.2 - 0.33 11.4 5.6 12 6.4 0.6 3.1 2 1 1 3 3 3 0 Spectrin repeat FUSC PF04632.12 EAU88465.2 - 8.7 4.7 6.0 2.7 6.4 1.4 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family CDP-OH_P_transf PF01066.21 EAU88466.2 - 4.9e-14 52.8 0.5 4.9e-14 52.8 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AAA PF00004.29 EAU88467.2 - 1.4e-30 106.4 0.0 3.5e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU88467.2 - 1.3e-08 34.4 0.0 3.5e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EAU88467.2 - 1.8e-05 25.2 0.8 0.0046 17.4 0.1 3.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 EAU88467.2 - 0.00065 20.3 0.2 0.015 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU88467.2 - 0.0013 19.0 0.4 0.031 14.6 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_6 PF12774.7 EAU88467.2 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 EAU88467.2 - 0.0023 18.0 0.1 0.027 14.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EAU88467.2 - 0.0027 17.8 0.0 0.015 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EAU88467.2 - 0.0059 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EAU88467.2 - 0.012 15.8 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EAU88467.2 - 0.012 15.3 0.4 0.083 12.6 0.0 2.4 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 EAU88467.2 - 0.048 13.9 0.6 0.2 11.9 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 EAU88467.2 - 0.062 13.1 0.9 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EAU88467.2 - 0.079 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_14 PF13173.6 EAU88467.2 - 0.089 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAU88467.2 - 0.1 12.3 0.0 0.35 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 EAU88467.2 - 0.13 11.7 0.2 6 6.2 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Mg_chelatase PF01078.21 EAU88467.2 - 0.14 11.5 0.3 0.46 9.8 0.3 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EAU88467.2 - 0.14 11.8 0.0 1.4 8.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EAU88467.2 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 EAU88467.2 - 0.16 11.3 0.0 3.1 7.2 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 EAU88467.2 - 0.16 12.3 0.1 0.35 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU88467.2 - 0.18 12.2 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SMC_Nse1 PF07574.13 EAU88468.2 - 1.3e-32 113.3 6.9 1.7e-32 112.9 1.1 2.4 2 1 0 2 2 2 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EAU88468.2 - 4.9e-11 42.8 9.5 8.8e-11 41.9 9.5 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 EAU88468.2 - 4.8e-06 26.8 8.2 8.1e-06 26.1 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 EAU88468.2 - 0.016 15.4 4.8 0.035 14.3 4.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EAU88468.2 - 0.026 14.7 0.9 0.052 13.7 0.9 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.22 EAU88468.2 - 0.036 13.9 1.4 0.077 12.9 1.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 EAU88468.2 - 0.33 10.8 7.9 0.58 10.0 7.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAU88468.2 - 0.85 9.7 3.7 1.5 8.9 3.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EAU88468.2 - 7.7 6.5 7.8 51 3.9 8.4 2.0 1 1 1 2 2 2 0 PHD-finger CDP-OH_P_transf PF01066.21 EAU88469.2 - 3.5e-12 46.9 1.0 8.9e-12 45.6 0.7 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CRCB PF02537.15 EAU88469.2 - 0.21 11.9 3.5 1.1 9.6 0.3 2.4 1 1 1 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) DNA_primase_lrg PF04104.14 EAU88470.2 - 4.6e-80 268.9 0.0 8e-80 268.0 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit SNF2_N PF00176.23 EAU88472.2 - 1e-54 185.6 0.0 1.7e-54 184.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EAU88472.2 - 5.7e-45 153.7 9.6 1e-44 152.9 9.6 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EAU88472.2 - 1e-16 61.3 0.0 2.5e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU88472.2 - 9e-08 32.3 0.0 2.5e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAU88472.2 - 3.2e-06 26.6 2.1 4.8e-06 25.9 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EAU88472.2 - 1e-05 24.9 0.1 1e-05 24.9 0.1 1.5 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EAU88472.2 - 0.099 12.9 0.1 1.1 9.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain U1snRNP70_N PF12220.8 EAU88472.2 - 5.1 7.8 8.4 0.45 11.2 2.6 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2722 PF10846.8 EAU88472.2 - 9.7 5.0 8.6 18 4.1 8.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) GYF PF02213.16 EAU88473.2 - 9.6e-09 34.8 4.2 2.8e-08 33.3 4.2 1.8 1 0 0 1 1 1 1 GYF domain PcfJ PF14284.6 EAU88473.2 - 0.028 14.3 0.7 0.061 13.2 0.7 1.5 1 0 0 1 1 1 0 PcfJ-like protein Rota_VP2 PF05087.12 EAU88473.2 - 1.3 7.1 2.7 1.7 6.7 2.7 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein PQ-loop PF04193.14 EAU88474.2 - 1.3e-40 137.0 6.3 6.1e-21 74.0 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat CLTH PF10607.9 EAU88474.2 - 1.9e-18 66.7 0.0 3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Endopep_inhib PF16800.5 EAU88474.2 - 0.022 14.7 0.0 0.063 13.2 0.0 1.6 2 0 0 2 2 2 0 IseA DL-endopeptidase inhibitor MtN3_slv PF03083.16 EAU88474.2 - 0.048 13.7 0.4 0.14 12.2 0.4 1.7 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange LisH PF08513.11 EAU88474.2 - 0.049 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 LisH Ribosomal_L3 PF00297.22 EAU88475.2 - 7.9e-20 71.2 1.3 9.6e-18 64.3 0.6 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 Cpn60_TCP1 PF00118.24 EAU88477.2 - 7.8e-152 506.3 11.9 9.2e-152 506.1 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSL_N PF06350.12 EAU88477.2 - 0.089 11.8 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus UFD1 PF03152.14 EAU88478.2 - 3.2e-61 205.8 0.0 4.2e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EAU88478.2 - 0.016 15.0 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 HMA PF00403.26 EAU88479.1 - 1.2e-10 41.6 0.4 1.9e-10 41.0 0.4 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain CGGC PF08821.11 EAU88479.1 - 0.0042 17.2 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 CGGC domain Methyltrans_Mon PF14314.6 EAU88479.1 - 0.039 12.0 0.0 0.04 12.0 0.0 1.0 1 0 0 1 1 1 0 Virus-capping methyltransferase AA_permease_2 PF13520.6 EAU88480.2 - 1.7e-64 218.3 39.3 2.1e-64 218.0 39.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EAU88480.2 - 2.6e-33 115.3 33.9 4.1e-33 114.7 33.9 1.3 1 0 0 1 1 1 1 Amino acid permease RNase_PH PF01138.21 EAU88481.2 - 2e-33 115.7 0.0 2.8e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EAU88481.2 - 3.1e-06 27.1 0.0 5.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PRCC PF10253.9 EAU88482.1 - 5.9e-32 112.2 11.0 5.9e-32 112.2 11.0 3.5 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting SPX PF03105.19 EAU88482.1 - 0.67 9.8 8.3 1 9.2 8.3 1.5 1 1 0 1 1 1 0 SPX domain DUF2315 PF10231.9 EAU88486.1 - 2.8e-25 88.8 0.4 3.9e-25 88.3 0.4 1.2 1 0 0 1 1 1 1 Apoptogenic protein 1 SAP PF02037.27 EAU88487.2 - 8.8e-11 41.3 0.8 8.8e-11 41.3 0.8 1.7 2 0 0 2 2 2 1 SAP domain CAP_N PF01213.19 EAU88488.1 - 2.1 7.7 3.4 3.6 7.0 3.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 EAU88489.1 - 1e-05 26.1 7.1 0.098 13.6 0.1 4.6 4 1 0 4 4 4 3 WD domain, G-beta repeat Swi3 PF07962.12 EAU88490.2 - 0.00012 21.9 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Methyltransf_PK PF05891.12 EAU88491.2 - 2.7e-48 164.4 0.0 4.5e-46 157.1 0.0 2.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EAU88491.2 - 9.1e-07 29.5 0.0 0.044 14.5 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EAU88491.2 - 0.00011 22.8 0.0 0.65 10.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EAU88491.2 - 0.0024 18.6 0.0 1.5 9.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain ADK PF00406.22 EAU88492.1 - 2.3e-46 157.6 0.0 3e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EAU88492.1 - 2.9e-20 73.1 0.0 4.5e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EAU88492.1 - 1.9e-13 50.1 0.0 3.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EAU88492.1 - 7.1e-07 29.8 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAU88492.1 - 0.0069 16.6 0.0 0.018 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EAU88492.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Epimerase PF01370.21 EAU88493.2 - 7.9e-10 38.6 0.3 6.1e-08 32.4 0.0 2.3 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EAU88493.2 - 1.2e-05 25.3 0.1 4.3e-05 23.5 0.0 2.0 3 0 0 3 3 3 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EAU88493.2 - 7.7e-05 21.8 0.0 0.0014 17.7 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EAU88493.2 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EAU88493.2 - 0.0079 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EAU88493.2 - 0.025 13.7 0.1 0.48 9.6 0.0 2.4 3 0 0 3 3 3 0 Male sterility protein Nuc_recep-AF1 PF11825.8 EAU88493.2 - 0.026 14.6 0.2 0.026 14.6 0.2 1.7 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 RmlD_sub_bind PF04321.17 EAU88493.2 - 0.029 13.5 0.0 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 EAU88493.2 - 0.21 11.1 0.1 0.49 9.9 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family PARP PF00644.20 EAU88494.2 - 2.1e-49 167.8 0.1 4.6e-49 166.7 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EAU88494.2 - 4.6e-40 136.9 0.1 8.1e-40 136.1 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EAU88494.2 - 4.1e-21 74.8 0.5 1e-20 73.5 0.5 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 EAU88494.2 - 7.6e-07 29.4 0.2 2.4e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EAU88494.2 - 2.5e-06 27.8 0.0 7.4e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EAU88494.2 - 2.5e-06 27.3 0.1 5.7e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EAU88494.2 - 0.08 13.2 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PBP1_TM PF14812.6 EAU88494.2 - 2.6 8.5 15.2 0.22 11.9 1.0 3.0 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DPBB_1 PF03330.18 EAU88495.2 - 6.9e-12 45.5 0.3 1.9e-11 44.1 0.1 1.8 1 1 1 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EAU88495.2 - 0.0022 17.8 0.3 0.0037 17.1 0.3 1.4 1 1 0 1 1 1 1 Barwin family SCAMP PF04144.13 EAU88496.1 - 4.2e-44 150.9 9.5 5.1e-44 150.6 9.5 1.1 1 0 0 1 1 1 1 SCAMP family Phage_tail_APC PF16778.5 EAU88496.1 - 0.06 13.2 0.4 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein NdhL PF10716.9 EAU88496.1 - 7 6.7 9.4 1.5 8.9 5.6 1.8 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit RRM_1 PF00076.22 EAU88497.1 - 3.2e-87 286.4 5.5 1.1e-22 79.6 0.8 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EAU88497.1 - 1.4e-26 92.4 1.0 4.9e-26 90.7 1.1 1.9 2 0 0 2 2 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EAU88497.1 - 9.4e-10 38.2 0.0 0.008 15.8 0.1 4.2 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAU88497.1 - 3.7e-05 23.7 8.5 0.012 15.6 2.5 3.6 4 0 0 4 4 4 2 RNA binding motif RRM_7 PF16367.5 EAU88497.1 - 6.2e-05 23.0 0.5 6 7.1 0.0 4.7 4 2 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EAU88497.1 - 0.00014 21.8 0.9 1.6 8.8 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EAU88497.1 - 0.0018 18.1 0.0 0.98 9.3 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif OB_RNB PF08206.11 EAU88497.1 - 0.016 14.9 2.7 12 5.7 0.3 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 EAU88497.1 - 0.14 12.3 0.6 23 5.2 0.1 3.5 3 0 0 3 3 3 0 Limkain b1 YflT PF11181.8 EAU88497.1 - 0.14 12.6 4.1 3.9 8.1 0.8 2.8 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF4407 PF14362.6 EAU88497.1 - 0.15 11.4 2.8 0.2 10.9 1.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Erf4 PF10256.9 EAU88497.1 - 0.17 12.0 0.8 6.8 6.8 0.1 3.4 3 1 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF1825 PF08855.10 EAU88497.1 - 0.3 11.0 1.5 12 5.9 0.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1825) DUF1919 PF08942.10 EAU88497.1 - 0.39 10.2 3.7 2.4 7.6 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1919) DEC-1_N PF04625.13 EAU88497.1 - 0.81 8.6 30.2 0.098 11.7 10.8 2.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Methyltransf_31 PF13847.6 EAU88498.2 - 2.2e-06 27.6 0.0 2.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU88498.2 - 2.4e-06 28.1 0.0 3.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EAU88498.2 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.6 EAU88498.2 - 2.6e-05 24.1 0.0 2.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU88498.2 - 0.0022 17.6 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EAU88498.2 - 0.0054 17.4 0.0 0.008 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EAU88498.2 - 0.0062 16.7 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.12 EAU88498.2 - 0.0066 16.2 0.0 0.0072 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 EAU88498.2 - 0.0084 15.4 0.0 0.0085 15.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain DOT1 PF08123.13 EAU88498.2 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 EAU88498.2 - 0.017 15.8 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EAU88498.2 - 0.019 14.7 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EAU88498.2 - 0.028 13.8 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EAU88498.2 - 0.067 12.5 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EAU88498.2 - 0.087 12.1 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 EAU88498.2 - 0.14 11.9 0.0 0.36 10.6 0.0 1.5 1 1 1 2 2 2 0 Met-10+ like-protein PhoLip_ATPase_C PF16212.5 EAU88499.1 - 0.0066 16.2 0.1 0.0086 15.9 0.1 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal CbtB PF09489.10 EAU88499.1 - 2.3 8.4 5.5 0.67 10.1 0.6 2.5 2 1 1 3 3 3 0 Probable cobalt transporter subunit (CbtB) SRP54 PF00448.22 EAU88500.1 - 1.1e-72 243.9 1.0 1.8e-72 243.1 1.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EAU88500.1 - 1.3e-30 105.9 0.3 1.3e-30 105.9 0.3 3.5 4 0 0 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 EAU88500.1 - 3.4e-20 72.0 3.3 8.2e-20 70.8 3.3 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 EAU88500.1 - 0.0017 18.4 0.1 0.0055 16.8 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EAU88500.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EAU88500.1 - 0.0022 17.0 3.4 0.003 16.6 0.7 2.4 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 EAU88500.1 - 0.0036 17.7 0.2 0.0036 17.7 0.2 2.5 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EAU88500.1 - 0.0068 16.1 2.2 0.013 15.3 0.1 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EAU88500.1 - 0.024 14.9 0.4 0.15 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain HTH_ParB PF17762.1 EAU88500.1 - 0.042 13.7 1.4 3 7.7 0.3 3.4 3 0 0 3 3 3 0 HTH domain found in ParB protein 6PF2K PF01591.18 EAU88500.1 - 0.045 13.1 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.23 EAU88500.1 - 0.056 13.5 0.2 0.25 11.4 0.2 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EAU88500.1 - 0.064 13.0 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EAU88500.1 - 0.08 12.4 0.6 9.8 5.6 0.7 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 EAU88500.1 - 0.12 12.3 1.1 1.2 9.1 1.1 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Thymidylate_kin PF02223.17 EAU88500.1 - 0.13 11.9 0.1 0.62 9.7 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.6 EAU88500.1 - 0.13 12.6 0.0 0.63 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 EAU88501.2 - 6.9e-08 33.0 2.5 3.1 8.8 0.0 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat SH2_2 PF14633.6 EAU88502.2 - 4.2e-79 264.9 0.2 4.2e-79 264.9 0.2 2.4 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 EAU88502.2 - 2.7e-28 98.4 0.0 5.4e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EAU88502.2 - 1.9e-26 92.6 0.1 6.9e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 EAU88502.2 - 1.8e-24 86.4 0.1 6.4e-24 84.6 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 EAU88502.2 - 8e-20 71.2 38.1 8e-20 71.2 38.1 5.2 4 2 1 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.24 EAU88502.2 - 3.3e-08 33.5 0.0 1.7e-05 24.8 0.0 2.8 2 0 0 2 2 2 2 SH2 domain HHH_9 PF17674.1 EAU88502.2 - 1.6e-06 28.9 2.4 1.2e-05 26.1 2.4 2.6 1 1 0 1 1 1 1 HHH domain S1 PF00575.23 EAU88502.2 - 1.8e-05 24.9 0.6 4.2e-05 23.8 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 EAU88502.2 - 2.9e-05 24.2 0.0 7.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 EAU88502.2 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain Inv-AAD PF18785.1 EAU88503.2 - 3.6e-27 94.8 0.0 5.1e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EAU88503.2 - 6.7e-16 58.0 0.3 9.1e-16 57.6 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAU88503.2 - 1.1e-05 25.2 0.3 4.9e-05 23.1 0.3 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Condensation PF00668.20 EAU88504.2 - 7.6e-96 321.5 0.0 1e-32 113.5 0.0 4.5 4 1 0 4 4 4 3 Condensation domain AMP-binding PF00501.28 EAU88504.2 - 2e-84 283.6 0.0 2.8e-84 283.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EAU88504.2 - 2.8e-25 88.4 0.4 6.5e-08 32.8 0.1 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.13 EAU88504.2 - 0.037 12.9 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 GH3 auxin-responsive promoter AMP-binding_C PF13193.6 EAU88504.2 - 0.04 14.9 0.0 0.17 12.9 0.0 2.2 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.6 EAU88505.1 - 4.2e-92 308.9 0.0 1e-89 301.1 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EAU88505.1 - 1.9e-05 24.7 0.0 9.5e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAU88505.1 - 2.4e-05 23.7 0.0 0.00027 20.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU88505.1 - 0.023 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAU88505.1 - 0.057 14.0 0.0 11 6.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EAU88505.1 - 0.077 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Ribosomal_L24e PF01246.20 EAU88506.2 - 2.8e-32 110.7 6.3 2.8e-32 110.7 6.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e HAGH_C PF16123.5 EAU88506.2 - 0.038 14.5 1.8 0.049 14.1 0.4 1.8 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus Cytochrom_C550 PF14495.6 EAU88506.2 - 0.067 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain zf-FCS PF06467.14 EAU88506.2 - 0.08 12.9 3.9 0.13 12.2 3.9 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif ATG_C PF09333.11 EAU88507.1 - 4.7e-37 126.2 0.2 4.7e-37 126.2 0.2 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EAU88507.1 - 3.5e-10 40.0 0.0 8.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EAU88507.1 - 5.2e-09 36.0 0.1 3.2e-08 33.4 0.0 2.4 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 EAU88507.1 - 0.00073 19.4 0.0 0.0023 17.7 0.1 1.7 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Lipase_GDSL PF00657.22 EAU88508.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NatB_MDM20 PF09797.9 EAU88510.2 - 3.7e-74 250.0 1.0 6.6e-74 249.1 1.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EAU88510.2 - 1.7e-07 31.6 5.1 0.0023 18.4 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU88510.2 - 0.0006 20.4 0.0 48 5.2 0.0 5.0 2 1 2 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 EAU88510.2 - 0.039 14.4 0.2 0.92 9.9 0.0 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 EAU88510.2 - 0.062 13.1 0.0 21 5.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TruB_N PF01509.18 EAU88512.1 - 3.1e-44 151.0 0.0 9.6e-44 149.4 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EAU88512.1 - 4.2e-05 23.6 0.1 0.00022 21.3 0.0 2.3 3 0 0 3 3 3 1 tRNA pseudouridylate synthase B C-terminal domain ESX-1_EspG PF14011.6 EAU88512.1 - 0.053 13.1 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 EspG family DHDPS PF00701.22 EAU88513.1 - 3.2e-27 95.0 0.0 1.3e-26 93.0 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PNTB PF02233.16 EAU88517.2 - 9.3e-173 575.4 21.2 9.3e-173 575.4 21.2 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EAU88517.2 - 2.1e-77 259.3 0.2 2.1e-77 259.3 0.2 2.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EAU88517.2 - 4.5e-45 153.3 0.1 2.3e-44 151.0 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EAU88517.2 - 1.3e-30 105.6 3.4 1.3e-30 105.6 3.4 4.9 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EAU88517.2 - 5.9e-05 22.5 0.2 0.86 8.9 0.1 3.8 4 0 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EAU88517.2 - 0.015 14.6 0.4 0.03 13.6 0.4 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dimer_Tnp_Tn5 PF02281.16 EAU88517.2 - 0.054 13.2 0.0 2 8.1 0.0 3.0 2 1 0 3 3 3 0 Transposase Tn5 dimerisation domain NAD_binding_8 PF13450.6 EAU88517.2 - 6.7 7.0 9.9 0.82 9.9 2.4 3.3 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain TMEM154 PF15102.6 EAU88518.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF2367 PF10164.9 EAU88521.2 - 2.9e-06 27.7 9.8 8.1e-06 26.3 9.6 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Kinesin PF00225.23 EAU88522.2 - 5.9e-104 347.6 0.0 1.6e-103 346.1 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAU88522.2 - 3.9e-25 88.5 0.0 4.7e-24 85.0 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EAU88522.2 - 1.9e-05 25.0 6.6 1.9e-05 25.0 6.6 4.3 3 1 2 6 6 6 1 Kinesin-associated microtubule-binding HBD PF18534.1 EAU88522.2 - 2.1 8.5 5.8 5.2 7.3 0.2 3.5 4 0 0 4 4 4 0 Helical bundle domain Elf1 PF05129.13 EAU88523.1 - 4.9e-30 103.4 1.3 5.9e-30 103.1 1.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.12 EAU88523.1 - 0.0048 17.4 1.3 0.0069 16.9 1.3 1.2 1 0 0 1 1 1 1 CHY zinc finger Nup96 PF12110.8 EAU88523.1 - 0.052 12.7 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Zn-ribbon_8 PF09723.10 EAU88523.1 - 0.082 13.0 1.0 0.15 12.2 1.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Kinesin PF00225.23 EAU88524.2 - 3.9e-113 377.8 0.7 3.9e-113 377.8 0.7 2.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EAU88524.2 - 3.8e-28 98.3 0.1 1.9e-27 96.1 0.1 2.2 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 EAU88524.2 - 8e-06 25.8 4.9 8e-06 25.8 4.9 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF465) DUF3800 PF12686.7 EAU88524.2 - 0.94 10.1 6.9 2.7e+02 2.2 4.4 4.1 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) Pro_Al_protease PF02983.14 EAU88524.2 - 2.2 8.4 6.1 1.6 8.9 1.6 3.2 3 0 0 3 3 3 0 Alpha-lytic protease prodomain Cbl_N PF02262.16 EAU88524.2 - 8.7 6.4 11.2 5.6 7.0 0.0 4.3 3 1 1 4 4 4 0 CBL proto-oncogene N-terminal domain 1 PUF PF00806.19 EAU88525.2 - 4.9e-61 199.1 0.1 5e-08 32.2 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TFIID_30kDa PF03540.13 EAU88525.2 - 0.17 11.8 0.6 17 5.4 0.0 3.4 3 0 0 3 3 3 0 Transcription initiation factor TFIID 23-30kDa subunit Sec16_C PF12931.7 EAU88526.2 - 3.1e-105 352.2 0.0 4.2e-105 351.7 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EAU88526.2 - 3e-29 102.0 0.0 2.9e-28 98.8 0.0 2.6 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region OST3_OST6 PF04756.13 EAU88527.1 - 3.5e-93 312.1 0.0 4.1e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EAU88527.1 - 0.00054 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DMT_YdcZ PF04657.13 EAU88527.1 - 0.011 16.1 0.6 0.011 16.1 0.6 2.3 2 0 0 2 2 2 0 Putative inner membrane exporter, YdcZ NADH-u_ox-rdase PF10785.9 EAU88527.1 - 0.23 12.2 2.0 0.51 11.1 0.3 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit 7TMR-DISM_7TM PF07695.11 EAU88527.1 - 0.64 9.9 8.5 2.1 8.2 8.5 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling PI3_PI4_kinase PF00454.27 EAU88528.2 - 4.2e-34 118.5 0.0 5.1e-33 114.9 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EAU88528.2 - 0.044 13.8 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Glyco_transf_15 PF01793.16 EAU88529.2 - 1.4e-101 340.0 7.7 1.8e-68 231.2 4.0 2.2 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.22 EAU88530.1 - 1.8e-82 276.9 1.4 2.1e-82 276.7 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin ABC_tran PF00005.27 EAU88531.2 - 3.1e-21 76.3 0.0 4.8e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU88531.2 - 3.6e-06 27.0 0.1 0.044 13.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EAU88531.2 - 8.3e-05 23.0 1.0 0.00016 22.1 1.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EAU88531.2 - 0.0002 21.1 0.1 0.00037 20.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EAU88531.2 - 0.00049 19.6 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU88531.2 - 0.0015 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 EAU88531.2 - 0.0016 18.4 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 EAU88531.2 - 0.0024 17.9 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAU88531.2 - 0.0025 18.1 0.2 0.0072 16.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EAU88531.2 - 0.0026 17.8 0.3 0.023 14.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EAU88531.2 - 0.0028 17.9 0.1 0.043 14.1 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EAU88531.2 - 0.0047 16.9 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EAU88531.2 - 0.012 16.1 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EAU88531.2 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 EAU88531.2 - 0.017 14.7 0.0 0.043 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EAU88531.2 - 0.021 15.1 0.5 0.093 13.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EAU88531.2 - 0.025 13.3 0.0 2.1 6.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAU88531.2 - 0.026 13.7 0.1 0.048 12.8 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 EAU88531.2 - 0.039 14.4 0.0 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EAU88531.2 - 0.067 13.0 0.0 0.18 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 EAU88531.2 - 0.076 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.16 EAU88531.2 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EAU88531.2 - 0.099 12.9 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EAU88531.2 - 0.12 12.3 0.2 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 EAU88531.2 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PEPCK_ATP PF01293.20 EAU88531.2 - 0.16 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase DUF2418 PF10332.9 EAU88533.2 - 5.8e-29 100.5 0.4 1.2e-28 99.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF3552 PF12072.8 EAU88534.1 - 0.56 9.6 8.2 0.45 9.9 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF3915 PF13054.6 EAU88534.1 - 4.8 7.2 4.9 22 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) tRNA-synt_2d PF01409.20 EAU88535.1 - 3.7e-48 164.2 0.5 6e-26 91.4 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EAU88535.1 - 8.8e-25 87.0 0.2 1.8e-24 86.0 0.1 1.6 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 EAU88536.1 - 5.1e-47 159.6 0.1 7.1e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 GrpE LRS4 PF10422.9 EAU88536.1 - 0.017 14.7 1.7 0.027 14.1 1.7 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 PKcGMP_CC PF16808.5 EAU88536.1 - 0.1 12.4 1.6 0.22 11.4 1.6 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PNGaseA PF12222.8 EAU88538.2 - 9.9e-75 252.0 0.0 8.4e-66 222.6 0.0 2.1 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF656 PF04920.12 EAU88538.2 - 0.14 12.0 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF656) Pmp3 PF01679.17 EAU88539.2 - 2.1e-16 59.8 1.9 2.9e-16 59.4 1.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator zf-H2C2_2 PF13465.6 EAU88540.2 - 1.1e-20 73.1 24.9 1.3e-06 28.6 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 EAU88540.2 - 3e-19 68.3 32.5 4.6e-05 23.6 4.4 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU88540.2 - 1.2e-10 41.3 26.6 0.024 15.5 0.9 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU88540.2 - 6.2e-05 23.2 2.1 2.2 8.7 0.0 4.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU88540.2 - 0.0012 19.1 8.1 0.18 12.2 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type FOXP-CC PF16159.5 EAU88540.2 - 0.0017 18.9 8.2 0.48 11.1 0.1 4.1 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EAU88540.2 - 0.026 14.8 7.8 1.3 9.3 0.9 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 EAU88540.2 - 0.097 12.4 0.1 0.097 12.4 0.1 4.7 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Gag_p17 PF00540.18 EAU88540.2 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) zf-C2H2_6 PF13912.6 EAU88540.2 - 0.16 12.0 0.2 0.16 12.0 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-TRAF PF02176.18 EAU88540.2 - 1.4 9.6 14.2 0.1 13.3 2.6 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger DUF2561 PF10812.8 EAU88540.2 - 5.9 6.9 4.7 1.9 8.5 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) FBPase PF00316.20 EAU88541.1 - 5e-75 251.1 0.2 6.5e-75 250.8 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EAU88541.1 - 0.0073 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family GCIP PF13324.6 EAU88543.1 - 9.9e-36 123.7 0.2 9.9e-36 123.7 0.2 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Baculo_PEP_C PF04513.12 EAU88543.1 - 6.2 6.9 8.1 6.2 6.9 0.2 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M41 PF01434.18 EAU88544.2 - 6.7e-56 189.2 0.3 1.1e-55 188.4 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EAU88544.2 - 7.6e-44 149.3 0.1 5.5e-43 146.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU88544.2 - 5.3e-12 45.3 0.0 1.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EAU88544.2 - 3.6e-05 24.2 5.0 0.00057 20.3 1.4 3.7 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EAU88544.2 - 4.4e-05 22.9 0.1 0.00076 18.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 EAU88544.2 - 4.8e-05 23.4 0.1 0.00025 21.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAU88544.2 - 4.9e-05 23.1 0.2 0.00045 20.0 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAU88544.2 - 0.00084 19.6 2.3 0.028 14.7 0.1 3.1 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EAU88544.2 - 0.0037 17.4 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EAU88544.2 - 0.004 16.7 1.8 0.32 10.6 0.4 2.8 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EAU88544.2 - 0.0057 16.1 0.5 0.015 14.6 0.5 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAU88544.2 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EAU88544.2 - 0.014 16.0 0.0 0.029 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAU88544.2 - 0.016 15.4 0.5 0.046 14.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EAU88544.2 - 0.022 14.7 0.2 0.19 11.7 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 EAU88544.2 - 0.023 14.8 0.0 0.076 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EAU88544.2 - 0.038 13.5 0.1 0.2 11.1 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EAU88544.2 - 0.046 12.9 0.0 0.095 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EAU88544.2 - 0.048 13.7 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EAU88544.2 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EAU88544.2 - 0.08 12.6 0.1 0.54 10.0 0.0 2.2 1 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 EAU88544.2 - 0.13 12.3 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Glyco_transf_54 PF04666.13 EAU88544.2 - 0.18 10.6 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region PRIMA1 PF16101.5 EAU88544.2 - 1.5 8.8 8.4 0.12 12.4 2.5 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DEAD_2 PF06733.15 EAU88545.1 - 5.5e-52 175.9 0.0 1.1e-51 175.0 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EAU88545.1 - 1.6e-47 161.6 6.2 4.6e-42 143.9 0.2 2.8 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EAU88545.1 - 4.8e-44 150.5 0.0 9.7e-44 149.5 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EAU88545.1 - 7.8e-05 22.7 0.1 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EAU88545.1 - 0.00086 19.1 0.0 0.52 10.1 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 EAU88545.1 - 0.017 13.9 0.8 0.33 9.6 0.8 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain FBA_3 PF08268.12 EAU88545.1 - 0.085 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box associated domain Glucan_synthase PF02364.15 EAU88546.2 - 0 1318.3 0.0 0 1317.9 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EAU88546.2 - 1.8e-42 144.7 0.1 5.2e-42 143.2 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 LRR_6 PF13516.6 EAU88547.2 - 1.2 9.3 3.0 66 3.9 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Cellulase PF00150.18 EAU88551.2 - 7.6e-15 55.1 0.3 1.3e-14 54.4 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 EAU88551.2 - 0.00087 19.0 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 EAU88551.2 - 0.0014 18.0 0.7 0.009 15.4 0.0 2.3 3 0 0 3 3 3 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 EAU88551.2 - 0.033 13.3 0.1 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain RAI16-like PF10257.9 EAU88552.2 - 2.3e-73 247.2 0.0 4.1e-73 246.3 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FAM176 PF14851.6 EAU88552.2 - 0.13 11.9 0.3 0.38 10.4 0.3 1.8 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 EAU88552.2 - 4.4 7.7 12.6 0.25 11.7 5.5 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EAU88552.2 - 4.8 7.5 7.4 0.69 10.2 1.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DnaJ PF00226.31 EAU88553.2 - 9.2e-22 76.9 1.8 2.7e-21 75.5 1.8 1.9 1 0 0 1 1 1 1 DnaJ domain PAP2 PF01569.21 EAU88553.2 - 6.9e-15 55.0 3.3 1.4e-14 54.1 3.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EAU88553.2 - 0.0059 16.7 0.8 0.038 14.1 0.3 2.3 2 0 0 2 2 2 1 Divergent PAP2 family SET PF00856.28 EAU88556.2 - 0.068 13.6 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 SET domain adh_short PF00106.25 EAU88557.1 - 2.4e-52 177.2 0.3 3.4e-52 176.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU88557.1 - 2.2e-34 119.0 0.7 2.9e-34 118.7 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU88557.1 - 3e-13 50.1 0.3 3.8e-13 49.7 0.3 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EAU88557.1 - 0.0016 17.6 0.1 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EAU88557.1 - 0.0071 16.1 0.5 0.018 14.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.10 EAU88557.1 - 0.0084 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Helicase_RecD PF05127.14 EAU88557.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Helicase THF_DHG_CYH_C PF02882.19 EAU88557.1 - 0.028 13.8 0.2 0.071 12.4 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EAU88557.1 - 0.029 14.3 0.1 0.054 13.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EAU88557.1 - 0.059 12.8 1.2 0.06 12.8 0.2 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAU88557.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_transf_15 PF01793.16 EAU88559.2 - 5.6e-96 321.6 5.7 1.3e-95 320.4 5.7 1.5 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Abhydrolase_1 PF00561.20 EAU88560.2 - 0.017 14.8 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold RWD PF05773.22 EAU88561.2 - 4.8e-20 72.0 1.5 1e-19 70.9 1.5 1.6 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EAU88561.2 - 1.7e-08 34.8 7.6 5.7e-08 33.1 7.5 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 FtsL PF04999.13 EAU88561.2 - 0.28 11.2 2.4 0.18 11.8 0.4 1.7 2 0 0 2 2 2 0 Cell division protein FtsL Ribosomal_S21 PF01165.20 EAU88562.2 - 3.8e-12 45.7 4.2 6.8e-12 44.9 4.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Fer2_4 PF13510.6 EAU88562.2 - 0.0019 18.2 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cyclin_N PF00134.23 EAU88564.2 - 1.9e-13 50.2 0.4 2.9e-12 46.5 0.4 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAU88564.2 - 6.7e-06 26.2 0.1 0.04 14.0 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.19 EAU88564.2 - 4.5e-05 23.4 0.1 0.00056 19.9 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EAU88564.2 - 0.013 15.9 0.1 0.043 14.2 0.1 2.0 1 1 1 2 2 2 0 Cyclin C-terminal domain IF-2B PF01008.17 EAU88565.2 - 7.1e-61 205.9 0.0 1.2e-60 205.2 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family PGBA_N PF15436.6 EAU88565.2 - 0.13 11.8 0.0 6 6.4 0.0 2.2 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal Peptidase_M24 PF00557.24 EAU88567.1 - 4.3e-53 180.1 0.0 4.9e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Acyltransferase PF01553.21 EAU88568.2 - 1.2e-12 47.6 0.0 3.9e-11 42.7 0.0 2.7 2 1 0 2 2 2 1 Acyltransferase IL23 PF16649.5 EAU88568.2 - 0.095 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Interleukin 23 subunit alpha NOC3p PF07540.11 EAU88570.2 - 3.9e-32 110.6 0.0 3.9e-32 110.6 0.0 2.3 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EAU88570.2 - 3.1e-19 69.7 0.0 3.1e-19 69.7 0.0 2.6 2 1 0 2 2 2 1 CBF/Mak21 family AAA_11 PF13086.6 EAU88570.2 - 0.083 12.7 6.7 0.19 11.5 6.7 1.5 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.6 EAU88570.2 - 0.15 12.1 6.5 0.35 11.0 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Muted PF14942.6 EAU88570.2 - 0.18 12.1 7.1 1.2 9.5 7.1 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein TEA PF01285.18 EAU88571.1 - 1.1e-16 60.6 1.0 2.9e-16 59.3 0.7 1.9 2 0 0 2 2 2 1 TEA/ATTS domain UEV PF05743.13 EAU88572.2 - 7.1e-34 116.3 0.0 1.1e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EAU88572.2 - 1.7e-28 98.4 0.2 3.9e-28 97.2 0.2 1.7 1 0 0 1 1 1 1 Vps23 core domain MSC PF09402.10 EAU88573.2 - 5.8e-91 305.4 0.0 8.1e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EAU88573.2 - 2.8e-12 46.1 0.0 5.8e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Pyr_redox_2 PF07992.14 EAU88574.1 - 1.3e-11 44.3 0.0 1.3e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU88574.1 - 0.00025 20.8 0.2 0.19 11.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Malic_M PF03949.15 EAU88574.1 - 0.00025 20.4 0.1 0.0004 19.7 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Pyr_redox_3 PF13738.6 EAU88574.1 - 0.039 13.2 0.1 2.8 7.1 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU88574.1 - 0.068 13.2 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EAU88574.1 - 0.14 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EAU88574.1 - 0.16 11.0 0.1 12 4.8 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Cu_bind_like PF02298.17 EAU88576.2 - 5.7e-05 23.0 0.2 0.00015 21.7 0.2 1.7 1 0 0 1 1 1 1 Plastocyanin-like domain DUF4477 PF14780.6 EAU88577.2 - 0.054 13.1 0.1 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Lamp PF01299.17 EAU88577.2 - 0.14 12.0 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Adaptin_N PF01602.20 EAU88578.2 - 1.8e-118 396.4 2.9 2.3e-118 396.0 2.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAU88578.2 - 8.3e-57 191.7 1.8 3.8e-54 183.1 0.1 2.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAU88578.2 - 3e-16 59.6 10.4 1.6e-06 28.4 0.5 4.9 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.22 EAU88578.2 - 2.4e-07 30.4 5.0 0.037 14.3 0.1 5.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 EAU88578.2 - 0.00087 19.7 1.5 52 4.5 0.0 5.9 7 0 0 7 7 7 0 HEAT-like repeat Arm PF00514.23 EAU88578.2 - 0.0012 18.8 0.2 0.98 9.6 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EAU88578.2 - 0.0028 17.2 0.0 0.045 13.3 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal U3snoRNP10 PF12397.8 EAU88578.2 - 0.039 14.3 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 DUF5578 PF17741.1 EAU88578.2 - 0.056 12.9 0.2 8.7 5.7 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5578) OTU PF02338.19 EAU88579.1 - 2.8e-20 73.1 0.0 6.9e-20 71.8 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EAU88579.1 - 0.0005 19.6 0.0 0.71 9.3 0.0 2.9 1 1 1 3 3 3 2 Peptidase C65 Otubain Casc1 PF12366.8 EAU88579.1 - 0.088 12.3 1.4 0.13 11.7 1.4 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 ECH_1 PF00378.20 EAU88581.1 - 6.9e-26 91.1 0.0 1.7e-25 89.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAU88581.1 - 4.8e-19 69.0 0.0 5.5e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase AA_permease PF00324.21 EAU88582.2 - 3.2e-122 408.5 39.6 3.9e-122 408.3 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAU88582.2 - 4.7e-27 94.9 48.0 8.3e-27 94.1 46.4 1.8 1 1 0 1 1 1 1 Amino acid permease Pirin PF02678.16 EAU88583.1 - 2.6e-30 104.6 0.5 1e-29 102.7 0.2 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 EAU88583.1 - 3.8e-26 91.5 0.1 9.9e-26 90.1 0.1 1.6 2 0 0 2 2 2 1 Pirin C-terminal cupin domain CLTH PF10607.9 EAU88585.1 - 4.1e-22 78.7 0.0 8.6e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EAU88585.1 - 1e-05 25.5 0.1 2.1e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Borrelia_P83 PF05262.11 EAU88585.1 - 0.014 13.9 0.7 0.019 13.5 0.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-RING_5 PF14634.6 EAU88585.1 - 0.016 15.2 0.3 0.031 14.2 0.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EAU88585.1 - 0.018 15.3 0.4 0.033 14.5 0.4 1.4 1 0 0 1 1 1 0 Ring finger domain Rtf2 PF04641.12 EAU88585.1 - 0.025 13.9 2.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 EAU88585.1 - 0.026 14.4 0.9 0.047 13.6 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WXG100 PF06013.12 EAU88585.1 - 0.055 13.7 3.1 0.46 10.7 0.1 2.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Prok-RING_4 PF14447.6 EAU88585.1 - 0.082 12.8 0.8 0.14 12.0 0.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RabGAP-TBC PF00566.18 EAU88586.1 - 7.2e-26 91.2 0.1 2.6e-13 50.1 0.1 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain G-patch PF01585.23 EAU88587.2 - 6.5e-09 35.6 3.8 1.4e-08 34.5 3.8 1.6 1 0 0 1 1 1 1 G-patch domain CsbD PF05532.12 EAU88588.1 - 0.0037 17.1 1.2 0.0037 17.1 1.2 1.7 2 0 0 2 2 2 1 CsbD-like RsfS PF02410.15 EAU88589.1 - 3.2e-07 30.7 0.0 5.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SHR3_chaperone PF08229.11 EAU88590.2 - 3.8e-38 130.3 0.1 4.5e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.6 EAU88590.2 - 0.11 12.9 0.1 0.62 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Tafi-CsgC PF10610.9 EAU88590.2 - 0.16 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Thin aggregative fimbriae synthesis protein LETM1 PF07766.13 EAU88591.2 - 7.1e-104 346.9 1.2 7.1e-104 346.9 1.2 1.4 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 EAU88591.2 - 0.00016 22.1 1.1 0.0049 17.3 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EAU88591.2 - 0.0052 16.2 0.0 0.2 11.3 0.0 3.4 4 0 0 4 4 4 1 EF hand SAP PF02037.27 EAU88591.2 - 0.0052 16.5 0.0 0.019 14.7 0.0 2.1 1 0 0 1 1 1 1 SAP domain EF-hand_8 PF13833.6 EAU88591.2 - 0.0063 16.3 0.1 0.056 13.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EAU88591.2 - 0.011 15.6 0.0 20 5.4 0.0 4.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 EAU88591.2 - 0.085 12.4 0.2 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 EF hand zf-C2HE PF16278.5 EAU88593.2 - 3.5e-16 59.4 0.5 3.5e-16 59.4 0.5 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EAU88593.2 - 1.2e-12 48.3 1.9 1.1e-11 45.2 1.6 2.4 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EAU88593.2 - 4.8e-10 40.0 0.2 1.5e-08 35.2 0.2 2.4 1 1 0 1 1 1 1 HIT domain Dynein_light PF01221.18 EAU88593.2 - 0.017 15.4 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 Dynein light chain type 1 ROS_MUCR PF05443.11 EAU88593.2 - 0.052 13.6 0.2 0.1 12.6 0.2 1.7 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein ox_reductase_C PF08635.10 EAU88594.2 - 5.6e-73 243.2 0.3 7.8e-73 242.8 0.3 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 EAU88594.2 - 2.2e-23 83.4 0.0 3.4e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EAU88594.2 - 0.0043 17.0 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sipho_Gp157 PF05565.11 EAU88595.1 - 0.00046 20.2 1.6 0.00067 19.7 1.6 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 ATG16 PF08614.11 EAU88595.1 - 0.0038 17.5 8.0 0.0038 17.5 8.0 1.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF730 PF05325.11 EAU88595.1 - 0.005 16.8 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF730) SKA2 PF16740.5 EAU88595.1 - 0.006 16.3 4.5 0.01 15.6 4.5 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Rx_N PF18052.1 EAU88595.1 - 0.011 16.0 4.9 0.017 15.3 4.9 1.3 1 0 0 1 1 1 0 Rx N-terminal domain UPF0242 PF06785.11 EAU88595.1 - 0.032 14.3 9.9 0.038 14.1 9.9 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ax_dynein_light PF10211.9 EAU88595.1 - 0.033 14.1 4.6 0.052 13.5 4.6 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain BLOC1S3 PF15753.5 EAU88595.1 - 0.054 13.6 2.8 0.065 13.4 2.8 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 MCU PF04678.13 EAU88595.1 - 0.09 12.9 0.9 0.11 12.6 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter OmpH PF03938.14 EAU88595.1 - 0.093 13.1 8.4 0.15 12.4 8.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 EAU88595.1 - 0.1 13.0 9.5 0.21 12.1 9.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB T2SSF PF00482.23 EAU88595.1 - 0.18 11.8 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F YabA PF06156.13 EAU88595.1 - 0.19 12.4 3.5 0.31 11.7 3.5 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Matrilin_ccoil PF10393.9 EAU88595.1 - 0.2 11.5 3.4 0.47 10.4 3.4 1.7 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Fungal_TACC PF12709.7 EAU88595.1 - 0.25 11.8 4.6 0.45 11.0 4.6 1.4 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins SlyX PF04102.12 EAU88595.1 - 0.37 11.5 4.9 0.26 11.9 2.4 2.0 2 0 0 2 2 2 0 SlyX DUF4446 PF14584.6 EAU88595.1 - 0.59 10.1 3.2 1.1 9.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Seryl_tRNA_N PF02403.22 EAU88595.1 - 0.72 10.1 8.9 0.46 10.7 7.1 1.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 EAU88595.1 - 1.9 8.9 6.4 0.44 11.0 2.6 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PIG-Y PF15159.6 EAU88596.1 - 3e-19 69.7 3.2 3.3e-19 69.5 3.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Sfi1 PF08457.10 EAU88597.2 - 6.2e-23 81.2 115.2 3.4e-11 42.4 33.8 5.3 1 1 3 4 4 4 4 Sfi1 spindle body protein NDUF_B4 PF07225.12 EAU88597.2 - 4.1 7.3 9.7 3.1 7.7 2.5 3.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Fungal_trans PF04082.18 EAU88598.2 - 6.5e-09 35.2 0.1 1.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU88598.2 - 0.011 15.9 14.9 0.021 14.9 14.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Histone_HNS PF00816.21 EAU88598.2 - 0.086 13.7 0.8 0.21 12.4 0.8 1.6 1 0 0 1 1 1 0 H-NS histone family Copper-bind PF00127.20 EAU88599.2 - 9.8e-05 22.7 0.1 0.0086 16.5 0.0 2.7 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EAU88599.2 - 0.00034 20.7 0.0 0.14 12.3 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain Cu_bind_like PF02298.17 EAU88599.2 - 0.029 14.4 2.4 0.17 11.9 0.3 2.9 2 2 0 2 2 2 0 Plastocyanin-like domain Rhodanese PF00581.20 EAU88599.2 - 0.13 12.7 0.0 4.5 7.8 0.0 2.4 3 0 0 3 3 3 0 Rhodanese-like domain MUG113 PF13455.6 EAU88600.2 - 7.2e-20 71.5 0.7 9.4e-19 67.9 0.0 2.6 3 0 0 3 3 3 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EAU88600.2 - 3.6e-13 50.0 0.9 1e-10 42.1 0.0 3.3 2 1 0 3 3 3 1 T5orf172 domain Ndc1_Nup PF09531.10 EAU88600.2 - 1 8.0 4.9 1.3 7.6 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.13 EAU88600.2 - 2.3 7.4 14.8 4.6 6.4 14.8 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1387 PF07139.11 EAU88600.2 - 9 5.9 6.2 14 5.3 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sas10_Utp3 PF04000.15 EAU88601.2 - 1.7e-08 35.0 0.0 4.3e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family YfhO PF09586.10 EAU88602.2 - 6.6 4.8 5.0 9.3 4.3 5.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ist1 PF03398.14 EAU88603.2 - 8e-40 136.4 0.0 1.7e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 EAU88603.2 - 2.1e-10 40.7 0.7 3.1e-08 33.6 0.0 3.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1697 PF08002.11 EAU88603.2 - 0.036 14.5 0.0 0.086 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) PIG-H PF10181.9 EAU88604.2 - 3.7e-16 58.7 0.0 5.9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Far-17a_AIG1 PF04750.14 EAU88605.2 - 2.9e-34 118.2 1.3 3.3e-34 118.0 1.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pept_tRNA_hydro PF01195.19 EAU88606.2 - 2.4e-22 79.7 0.0 3.2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Nodulin-like PF06813.13 EAU88607.2 - 0.0011 18.6 6.6 0.0011 18.6 6.6 1.6 2 0 0 2 2 2 1 Nodulin-like Lyase_1 PF00206.20 EAU88608.1 - 9.3e-94 314.3 0.0 1.4e-93 313.7 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EAU88608.1 - 2.4e-25 89.1 0.1 4.9e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Syntaxin PF00804.25 EAU88609.2 - 7e-32 110.7 11.5 1.2e-31 109.9 11.5 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EAU88609.2 - 1.4e-12 47.4 0.6 3e-12 46.3 0.6 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EAU88609.2 - 2.9e-07 30.8 3.8 2.9e-07 30.8 3.8 3.0 2 1 1 3 3 3 1 Syntaxin-like protein Synaptobrevin PF00957.21 EAU88609.2 - 0.0043 16.8 4.0 0.014 15.1 0.6 2.5 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.21 EAU88609.2 - 0.013 15.3 6.5 0.02 14.7 3.0 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.10 EAU88609.2 - 0.022 14.8 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Trep_Strep PF09605.10 EAU88609.2 - 0.035 14.1 0.1 0.054 13.5 0.1 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) LMBR1 PF04791.16 EAU88609.2 - 0.047 12.6 2.3 0.065 12.1 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spectrin PF00435.21 EAU88609.2 - 0.055 14.0 5.5 1.8 9.1 0.0 3.2 3 1 0 3 3 3 0 Spectrin repeat MLTR_LBD PF17765.1 EAU88609.2 - 0.08 13.1 0.1 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Ycf34 PF10718.9 EAU88609.2 - 0.089 13.5 1.1 0.46 11.2 0.1 2.2 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 Herpes_US9 PF06072.11 EAU88609.2 - 0.17 11.8 1.1 0.48 10.3 1.1 1.8 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4094 PF13334.6 EAU88609.2 - 0.19 12.2 2.8 2.3 8.7 0.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) V_ATPase_I PF01496.19 EAU88609.2 - 0.33 8.8 11.4 0.2 9.6 8.5 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CLZ PF16526.5 EAU88609.2 - 0.37 11.2 3.6 1.8 9.0 0.2 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SKA1 PF07160.12 EAU88609.2 - 0.44 10.4 10.5 0.11 12.3 2.5 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 NPV_P10 PF05531.12 EAU88609.2 - 1.4 9.5 5.0 9.5 6.8 1.8 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 EAU88609.2 - 1.5 7.3 10.4 0.25 9.8 3.0 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family V-SNARE PF05008.15 EAU88609.2 - 1.6 9.1 14.6 0.12 12.8 2.2 3.6 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus WXG100 PF06013.12 EAU88609.2 - 2.5 8.4 11.7 3.3 8.0 0.0 4.0 2 2 1 3 3 3 0 Proteins of 100 residues with WXG AAA_23 PF13476.6 EAU88609.2 - 5.2 7.5 9.6 7.5 7.0 8.6 1.5 1 1 0 1 1 1 0 AAA domain zf-AN1 PF01428.16 EAU88610.1 - 4.5e-10 39.5 6.7 4.5e-10 39.5 6.7 1.7 2 1 0 2 2 2 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 EAU88610.1 - 0.0018 17.9 0.9 0.0057 16.3 0.9 1.9 1 0 0 1 1 1 1 Rubredoxin metal binding domain Aminotran_1_2 PF00155.21 EAU88611.2 - 7.2e-90 301.8 0.0 8.1e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.22 EAU88612.2 - 1.1e-16 59.5 9.7 0.019 15.2 0.1 9.7 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.6 EAU88612.2 - 8e-14 51.8 5.3 0.0088 16.4 0.1 7.0 5 2 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 EAU88612.2 - 0.027 14.5 0.0 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EAU88612.2 - 0.15 12.6 16.0 0.25 11.9 0.7 6.1 7 1 0 7 7 7 0 HEAT-like repeat GAS PF13851.6 EAU88616.2 - 0.00083 18.8 0.5 0.0012 18.3 0.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding PEARLI-4 PF05278.12 EAU88616.2 - 0.015 14.9 2.1 0.022 14.3 2.1 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) TPD52 PF04201.15 EAU88616.2 - 0.019 14.6 2.5 0.029 14.0 2.5 1.2 1 0 0 1 1 1 0 Tumour protein D52 family Sugarporin_N PF11471.8 EAU88616.2 - 0.053 13.5 1.4 0.15 12.0 1.3 1.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF948 PF06103.11 EAU88616.2 - 0.07 13.4 0.3 0.16 12.2 0.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF4140 PF13600.6 EAU88616.2 - 0.11 13.0 1.6 0.17 12.3 1.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 EAU88616.2 - 0.15 12.1 0.4 0.27 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 EAU88616.2 - 0.46 9.7 3.4 0.34 10.1 0.7 1.8 2 0 0 2 2 2 0 Monopolar spindle protein 2 FUN14 PF04930.15 EAU88618.1 - 1.4e-21 76.7 0.7 2.3e-21 76.0 0.7 1.4 1 0 0 1 1 1 1 FUN14 family Peptidase_S8 PF00082.22 EAU88620.2 - 6.9e-37 127.3 1.7 9.6e-37 126.8 1.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EAU88620.2 - 7.2e-26 90.0 0.2 1.3e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 EAU88620.2 - 0.039 14.7 0.7 0.89 10.4 1.2 2.7 2 1 0 2 2 2 0 Peptidase S8 pro-domain PGF-CTERM PF18204.1 EAU88620.2 - 0.081 12.9 1.0 0.23 11.5 1.0 1.8 1 0 0 1 1 1 0 PGF-CTERM motif Peptidase_S8_N PF16361.5 EAU88620.2 - 0.15 12.6 0.0 0.66 10.5 0.0 2.0 1 1 1 2 2 2 0 N-terminal of Subtilase family PEP-CTERM PF07589.11 EAU88620.2 - 0.33 11.1 1.4 0.93 9.7 1.4 1.7 1 0 0 1 1 1 0 PEP-CTERM motif Adeno_terminal PF02459.15 EAU88620.2 - 1.4 7.2 2.6 2.2 6.6 2.6 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein TRM PF02005.16 EAU88621.2 - 8.2e-122 407.0 0.0 1.1e-121 406.5 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EAU88621.2 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Pkinase PF00069.25 EAU88622.2 - 1.6e-69 234.3 0.0 2.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU88622.2 - 1.1e-46 159.2 0.0 1.7e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EAU88622.2 - 3e-16 59.6 0.0 6.6e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EAU88622.2 - 5.3e-12 46.0 0.1 1.1e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EAU88622.2 - 2.5e-11 43.5 0.1 4.8e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EAU88622.2 - 0.00015 21.2 0.0 0.0047 16.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EAU88622.2 - 0.0024 16.7 0.0 0.0042 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SAM_4 PF18017.1 EAU88622.2 - 0.0091 15.9 0.3 0.021 14.8 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Spt5_N PF11942.8 EAU88622.2 - 0.037 15.0 4.1 0.043 14.8 1.2 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Alpha-amylase PF00128.24 EAU88623.2 - 2.4e-19 70.1 2.2 7.9e-17 61.8 2.2 2.8 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 EAU88623.2 - 9.9e-16 58.2 0.0 1.8e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EAU88623.2 - 1.2e-07 31.4 0.0 2.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2040 PF09745.9 EAU88624.2 - 4.2e-40 136.6 21.0 4.2e-40 136.6 21.0 3.2 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) TFIID-18kDa PF02269.16 EAU88625.2 - 8.6e-21 73.8 1.0 9.4e-21 73.6 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit DUF5591 PF17884.1 EAU88625.2 - 1.1 9.1 6.7 1.4 8.8 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5591) SARG PF15385.6 EAU88625.2 - 2.8 7.1 7.7 3.7 6.7 7.7 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DUF4211 PF13926.6 EAU88626.1 - 6.8e-37 126.7 1.4 4.7e-36 124.0 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) C1_1 PF00130.22 EAU88627.2 - 2.9e-07 30.3 2.5 2.9e-07 30.3 2.5 2.4 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.6 EAU88627.2 - 9.3e-05 21.4 0.1 0.00018 20.4 0.1 1.4 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 PHD PF00628.29 EAU88627.2 - 0.0032 17.3 12.1 0.11 12.4 1.7 2.5 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 EAU88627.2 - 0.15 12.4 14.1 1.9 8.9 5.8 2.5 2 0 0 2 2 2 0 C1 domain DUF1840 PF08895.11 EAU88627.2 - 0.17 12.3 0.1 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Zn_ribbon_17 PF17120.5 EAU88627.2 - 0.38 10.4 14.9 0.63 9.7 4.3 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD_2 PF13831.6 EAU88627.2 - 0.46 10.1 4.6 6.7 6.4 0.4 2.7 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 EAU88627.2 - 2.3 8.2 11.7 0.94 9.5 1.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TRAPPC9-Trs120 PF08626.11 EAU88629.2 - 4.5e-155 517.9 0.0 5e-126 421.7 0.0 3.0 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Vps55 PF04133.14 EAU88630.1 - 3.8e-43 146.2 7.1 4.2e-43 146.0 7.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 CbiQ PF02361.16 EAU88630.1 - 0.09 12.4 5.7 0.12 12.0 5.7 1.2 1 0 0 1 1 1 0 Cobalt transport protein Chromo PF00385.24 EAU88631.2 - 9.6e-08 31.8 4.9 1.7e-07 31.0 4.9 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.14 EAU88633.2 - 2.2e-09 37.0 0.0 5.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF659 PF04937.15 EAU88633.2 - 0.00014 21.7 0.1 0.0004 20.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) P16-Arc PF04699.14 EAU88633.2 - 0.064 13.8 2.1 3.2 8.2 0.1 2.7 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) SDA1 PF05285.12 EAU88633.2 - 4.3 6.7 22.8 0.25 10.7 9.7 2.3 2 0 0 2 2 2 0 SDA1 Inhibitor_I71 PF12628.7 EAU88634.2 - 0.1 12.4 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Glucos_trans_II PF14264.6 EAU88635.2 - 0.029 13.7 0.6 0.037 13.4 0.6 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII CbiQ PF02361.16 EAU88635.2 - 0.11 12.1 7.5 0.65 9.6 5.8 2.0 1 1 1 2 2 2 0 Cobalt transport protein FtsX PF02687.21 EAU88635.2 - 0.24 11.9 3.2 0.23 12.0 0.7 2.0 2 0 0 2 2 2 0 FtsX-like permease family TraL PF07178.11 EAU88635.2 - 0.49 10.9 6.6 0.57 10.7 0.2 2.8 2 1 1 3 3 3 0 TraL protein mRNA_cap_enzyme PF01331.19 EAU88637.1 - 2.6e-52 177.5 0.1 3.6e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EAU88637.1 - 4.4e-31 107.7 0.0 6.9e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EAU88637.1 - 2.5e-09 37.1 0.0 9.3e-07 28.7 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Skp1 PF01466.19 EAU88638.2 - 2.9e-29 100.9 0.5 4.7e-29 100.2 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EAU88638.2 - 9.9e-25 86.5 0.7 2.7e-24 85.1 0.0 2.1 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 EAU88638.2 - 0.0023 18.2 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF615 PF04751.14 EAU88638.2 - 0.064 13.2 0.1 0.15 12.1 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF615) Ribosomal_L27 PF01016.19 EAU88639.2 - 7e-33 112.5 0.4 9e-33 112.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein PhyH PF05721.13 EAU88639.2 - 0.12 12.6 0.0 0.17 12.2 0.0 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) F-box-like PF12937.7 EAU88641.1 - 7.3e-05 22.6 0.5 0.00033 20.5 0.5 2.2 1 1 0 1 1 1 1 F-box-like DUF1456 PF07308.13 EAU88641.1 - 0.033 14.5 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) LRR_4 PF12799.7 EAU88641.1 - 0.43 11.1 7.8 29 5.3 0.2 4.9 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU88642.1 - 2.3e-08 33.8 0.6 6.8e-08 32.3 0.6 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU88642.1 - 0.027 14.3 0.4 3.8 7.5 0.0 2.8 2 0 0 2 2 2 0 F-box domain Lipase_3 PF01764.25 EAU88644.1 - 7.3e-07 29.2 0.0 2e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.12 EAU88644.1 - 0.038 13.9 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 EAU88644.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU88644.1 - 0.13 12.8 10.8 0.073 13.7 8.1 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family Amidohydro_1 PF01979.20 EAU88645.1 - 1.5e-57 195.5 0.0 4.7e-56 190.6 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EAU88645.1 - 5.8e-08 32.6 0.0 0.0026 17.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EAU88645.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Methyltransf_31 PF13847.6 EAU88648.2 - 1.3e-27 96.5 0.0 2e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU88648.2 - 2.7e-21 76.1 0.0 6.1e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU88648.2 - 1.1e-19 70.9 0.0 2.1e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU88648.2 - 2.2e-13 50.1 0.0 4.9e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EAU88648.2 - 7.9e-11 42.6 0.0 1.3e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU88648.2 - 1.4e-10 41.2 0.0 2.6e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAU88648.2 - 4.5e-08 32.8 0.1 7.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EAU88648.2 - 1.6e-07 31.0 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EAU88648.2 - 3.4e-07 30.2 0.0 2.1e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rhodanese PF00581.20 EAU88648.2 - 3.5e-05 24.3 0.2 0.0001 22.8 0.2 1.9 1 1 0 1 1 1 1 Rhodanese-like domain Methyltransf_8 PF05148.15 EAU88648.2 - 0.00025 21.0 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_2 PF00891.18 EAU88648.2 - 0.00058 19.2 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 EAU88648.2 - 0.00078 18.8 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.6 EAU88648.2 - 0.00089 20.3 0.0 0.69 11.0 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 EAU88648.2 - 0.0032 17.2 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_16 PF10294.9 EAU88648.2 - 0.15 11.8 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase MetW PF07021.12 EAU88648.2 - 0.19 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Plavaka PF18759.1 EAU88650.2 - 0.024 13.9 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Plavaka transposase Spt4 PF06093.13 EAU88651.2 - 0.15 12.2 0.2 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger DnaJ PF00226.31 EAU88652.2 - 0.042 14.0 0.3 0.46 10.7 0.4 2.3 2 0 0 2 2 2 0 DnaJ domain FeoB_Cyto PF17910.1 EAU88653.2 - 0.002 18.6 0.5 0.002 18.6 0.5 2.1 2 0 0 2 2 2 1 FeoB cytosolic helical domain RPW8 PF05659.11 EAU88653.2 - 0.02 14.6 0.6 0.058 13.1 0.6 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PSII_Pbs27 PF13326.6 EAU88653.2 - 0.18 12.1 3.0 12 6.2 0.3 2.7 3 0 0 3 3 3 0 Photosystem II Pbs27 Phosducin PF02114.16 EAU88654.2 - 7.6e-21 74.2 0.2 1.2e-07 31.0 0.0 3.2 2 1 1 3 3 3 3 Phosducin DUF4407 PF14362.6 EAU88654.2 - 0.53 9.6 4.6 0.74 9.1 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) peroxidase PF00141.23 EAU88655.2 - 5.7e-22 78.5 0.0 9.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4537 PF15057.6 EAU88657.1 - 0.0016 18.5 0.0 0.0041 17.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PWWP PF00855.17 EAU88657.1 - 0.0045 17.4 0.1 0.34 11.3 0.0 3.1 2 0 0 2 2 2 1 PWWP domain WSD PF15613.6 EAU88657.1 - 6.6 7.3 9.1 46 4.6 0.4 3.7 3 0 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif GDA1_CD39 PF01150.17 EAU88658.1 - 1e-97 327.5 0.0 1.1e-96 324.1 0.0 1.9 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AA_permease PF00324.21 EAU88661.1 - 2.7e-100 336.2 29.1 2.7e-100 336.2 29.1 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAU88661.1 - 2.1e-16 59.8 38.5 2.9e-16 59.3 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease GGACT PF06094.12 EAU88663.2 - 2.4e-08 34.6 0.0 3.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EAU88663.2 - 7e-05 23.1 0.1 0.0001 22.6 0.1 1.3 1 0 0 1 1 1 1 AIG2-like family Imm17 PF15562.6 EAU88663.2 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 17 MnmE_helical PF12631.7 EAU88664.2 - 3.2e-48 164.6 0.1 4e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EAU88664.2 - 5.5e-36 123.4 0.0 1e-35 122.5 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EAU88664.2 - 4.7e-19 68.5 0.0 1e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU88664.2 - 5.4e-05 23.3 0.0 0.00022 21.4 0.0 1.9 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 EAU88664.2 - 0.00046 19.7 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_28 PF13521.6 EAU88664.2 - 0.0081 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAU88664.2 - 0.013 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Imm44 PF15571.6 EAU88664.2 - 0.1 12.9 0.4 12 6.1 0.1 2.2 1 1 1 2 2 2 0 Immunity protein 44 cobW PF02492.19 EAU88664.2 - 0.11 12.1 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L7Ae PF01248.26 EAU88665.1 - 1.7e-25 88.6 0.1 2.1e-25 88.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EAU88665.1 - 0.0004 20.5 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EAU88665.1 - 0.00052 19.9 0.0 0.00074 19.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Mannosyl_trans PF05007.13 EAU88666.1 - 4.8e-77 259.3 12.1 6.8e-77 258.8 12.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EAU88666.1 - 2.9e-14 52.9 3.8 2.9e-14 52.9 3.8 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EAU88666.1 - 0.0014 18.4 8.5 0.0014 18.4 8.5 2.9 1 1 0 2 2 2 1 Glycosyltransferase family 87 Arf PF00025.21 EAU88667.1 - 5.4e-68 227.9 0.0 6e-68 227.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EAU88667.1 - 7e-13 48.5 0.0 2.3e-09 36.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EAU88667.1 - 8.3e-10 38.4 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAU88667.1 - 1e-07 32.2 0.0 2.4e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAU88667.1 - 1.9e-07 31.1 0.0 3.5e-07 30.3 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EAU88667.1 - 3.6e-06 26.7 0.0 4.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAU88667.1 - 7.1e-05 22.3 0.0 8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAU88667.1 - 0.0045 16.5 0.0 0.088 12.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EAU88667.1 - 0.052 13.3 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KASH_CCD PF14662.6 EAU88668.1 - 0.0037 17.1 8.7 0.0094 15.8 8.7 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH AIRS PF00586.24 EAU88668.1 - 0.094 13.4 0.0 0.22 12.2 0.0 1.6 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain GAS PF13851.6 EAU88668.1 - 0.15 11.4 13.0 0.33 10.3 13.0 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EAU88668.1 - 0.3 11.1 5.7 19 5.3 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EAU88668.1 - 2.1 8.5 19.6 5 7.3 19.6 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YabA PF06156.13 EAU88668.1 - 2.5 8.8 6.1 8.2 7.1 6.1 1.9 1 0 0 1 1 1 0 Initiation control protein YabA PAP2 PF01569.21 EAU88669.2 - 0.074 12.8 0.0 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 PAP2 superfamily Cofilin_ADF PF00241.20 EAU88672.2 - 1.4e-15 57.2 0.0 1.4e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ArfGap PF01412.18 EAU88673.2 - 0.015 15.4 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf_UBZ PF18439.1 EAU88673.2 - 0.017 14.7 3.3 0.47 10.1 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger LIM PF00412.22 EAU88673.2 - 0.13 12.5 2.6 0.14 12.4 0.6 1.9 2 0 0 2 2 2 0 LIM domain DZR PF12773.7 EAU88673.2 - 0.38 10.8 1.5 12 6.0 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon Fungal_trans PF04082.18 EAU88675.2 - 5e-22 78.2 0.0 1.5e-21 76.6 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU88675.2 - 1e-09 38.4 4.4 2.1e-09 37.3 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EAU88675.2 - 0.44 10.5 53.3 0.53 10.2 17.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_17 PF00332.18 EAU88679.2 - 1.8e-08 34.4 0.0 2.3e-07 30.7 0.0 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 Pro_isomerase PF00160.21 EAU88681.2 - 1.4e-50 171.7 0.0 1.7e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EAU88682.2 - 7.2e-36 121.6 29.1 3e-06 27.8 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EAU88682.2 - 3.1e-13 49.4 1.3 7.9e-13 48.1 1.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU88682.2 - 2.9e-11 42.9 0.7 7.5e-11 41.6 0.7 1.8 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EAU88682.2 - 4.7e-06 26.8 0.8 9.8 6.6 0.0 5.5 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAU88682.2 - 0.00017 20.4 7.4 0.16 10.6 0.1 4.2 2 1 3 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EAU88682.2 - 0.0095 15.5 5.8 2.5 7.6 0.3 3.3 3 1 1 4 4 4 3 PQQ-like domain Arylsulfotran_2 PF14269.6 EAU88682.2 - 0.2 11.0 1.9 0.44 9.9 0.1 2.4 4 0 0 4 4 4 0 Arylsulfotransferase (ASST) PALB2_WD40 PF16756.5 EAU88682.2 - 0.43 9.4 3.9 13 4.5 0.6 3.4 2 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Fungal_trans PF04082.18 EAU88683.2 - 1.6e-19 70.0 0.3 5.1e-19 68.3 0.1 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU88683.2 - 6e-06 26.3 7.5 1.3e-05 25.3 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 EAU88683.2 - 4 7.3 19.3 0.41 10.6 11.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PSD2 PF07624.11 EAU88684.2 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) IGFL PF14653.6 EAU88684.2 - 0.088 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Insulin growth factor-like family CTP_transf_like PF01467.26 EAU88686.2 - 1e-07 32.3 0.0 1.8e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like Nuc_sug_transp PF04142.15 EAU88687.1 - 4.3e-96 321.8 11.5 8.7e-96 320.8 11.5 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EAU88687.1 - 0.00047 20.3 1.2 0.00047 20.3 1.2 2.8 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 EAU88687.1 - 0.0021 17.3 12.6 0.019 14.2 12.6 2.1 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 EAU88687.1 - 0.038 13.3 16.9 0.022 14.1 2.9 3.6 2 2 1 3 3 3 0 Triose-phosphate Transporter family DUF202 PF02656.15 EAU88687.1 - 4.8 7.7 9.7 0.59 10.6 0.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) CxC5 PF18718.1 EAU88688.2 - 6.8e-38 129.3 2.3 1e-37 128.8 2.3 1.3 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases RTC4 PF14474.6 EAU88689.2 - 1e-12 48.3 0.0 3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain Maf_N PF08383.11 EAU88689.2 - 0.24 11.2 0.4 0.71 9.7 0.1 1.9 2 0 0 2 2 2 0 Maf N-terminal region Mit_ribos_Mrp51 PF11709.8 EAU88692.1 - 2.2e-15 57.1 0.4 2.6e-14 53.6 0.4 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit AIDA PF16168.5 EAU88693.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk UPF1_Zn_bind PF09416.10 EAU88694.1 - 1.9e-69 232.5 2.5 1.9e-69 232.5 2.5 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EAU88694.1 - 6.1e-59 199.0 0.0 1.1e-58 198.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU88694.1 - 1.2e-51 176.0 3.7 7.7e-30 104.5 0.4 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EAU88694.1 - 2.4e-35 120.7 0.0 4.9e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EAU88694.1 - 9.8e-15 54.8 0.1 5.3e-14 52.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU88694.1 - 5.8e-12 46.2 0.1 1.6e-11 44.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU88694.1 - 4.6e-06 26.6 0.0 0.12 12.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EAU88694.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EAU88694.1 - 2.6e-05 23.7 0.6 0.00047 19.5 0.0 2.7 2 2 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EAU88694.1 - 3.6e-05 23.4 0.1 0.0026 17.4 0.1 2.4 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EAU88694.1 - 0.00011 22.2 0.1 0.00023 21.1 0.1 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EAU88694.1 - 0.026 13.7 0.2 1.5 7.9 0.1 2.2 1 1 0 2 2 2 0 PIF1-like helicase AAA_10 PF12846.7 EAU88694.1 - 0.026 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.29 EAU88694.1 - 0.03 14.1 0.2 0.059 13.1 0.2 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU88694.1 - 0.032 14.5 0.0 0.084 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAU88694.1 - 0.043 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 EAU88694.1 - 0.065 12.7 0.1 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_S27e PF01667.17 EAU88694.1 - 0.08 12.7 0.5 0.24 11.1 0.5 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 AAA_25 PF13481.6 EAU88694.1 - 0.084 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EAU88694.1 - 0.09 12.1 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EAU88694.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EAU88694.1 - 0.14 12.5 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-UBP PF02148.19 EAU88694.1 - 3.7 7.9 5.9 14 6.1 5.9 2.1 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Host_attach PF10116.9 EAU88695.1 - 0.41 11.2 3.5 0.46 11.0 1.3 2.1 2 0 0 2 2 2 0 Protein required for attachment to host cells DUF5349 PF17298.2 EAU88695.1 - 1 9.0 9.8 1.9 8.1 9.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Metallophos PF00149.28 EAU88697.1 - 7.1e-14 52.8 0.7 1.1e-13 52.2 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU88697.1 - 1.4e-06 28.6 0.0 2.5e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2204 PF09970.9 EAU88698.1 - 0.0036 17.0 0.0 0.0074 15.9 0.0 1.5 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) Radical_SAM_C PF16199.5 EAU88700.1 - 1.7e-29 101.6 0.0 3.2e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EAU88700.1 - 1.1e-17 64.9 0.2 4e-17 63.1 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EAU88700.1 - 6.9e-11 42.4 0.1 1.4e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU88700.1 - 2.2e-06 27.6 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU88700.1 - 0.0029 18.0 0.1 0.009 16.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU88700.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein MMM1 PF10296.9 EAU88701.2 - 1.9e-13 50.2 0.1 1.3e-09 37.5 0.1 2.8 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 F-box-like PF12937.7 EAU88702.2 - 1.8e-05 24.5 0.4 5.5e-05 23.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like APG9 PF04109.16 EAU88703.2 - 8.6e-161 536.2 5.0 1.2e-100 337.9 0.0 3.1 1 1 2 3 3 3 3 Autophagy protein Apg9 LcrG PF07216.12 EAU88703.2 - 0.86 9.6 3.1 4.2 7.4 0.1 2.8 3 0 0 3 3 3 0 LcrG protein DTHCT PF08070.11 EAU88703.2 - 2.4 8.9 5.9 6.9 7.5 5.9 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region HMGL-like PF00682.19 EAU88704.1 - 5.4e-75 252.3 0.0 8.7e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EAU88704.1 - 3e-45 153.4 0.0 3.2e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain tRNA-synt_1c PF00749.21 EAU88705.1 - 4.3e-113 377.4 0.0 5.7e-113 377.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EAU88705.1 - 1.2e-35 122.9 0.0 2.4e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 EAU88705.1 - 4.2e-06 26.7 0.1 1.2e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU88705.1 - 1.3e-05 25.3 0.1 3.4e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU88705.1 - 2.9e-05 24.2 0.3 0.0057 16.8 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EAU88705.1 - 0.0094 15.3 1.9 0.017 14.5 0.9 1.7 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain GST_C_6 PF17171.4 EAU88705.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AIMP2_LysRS_bd PF16780.5 EAU88705.1 - 0.16 11.7 0.2 0.37 10.6 0.2 1.7 1 0 0 1 1 1 0 AIMP2 lysyl-tRNA synthetase binding domain NUDIX PF00293.28 EAU88706.1 - 1.8e-07 31.2 0.0 2.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CPDase PF07823.11 EAU88707.1 - 1.4e-14 54.3 0.9 6.2e-12 45.6 0.9 2.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EAU88707.1 - 7e-06 26.0 0.1 0.0017 18.3 0.0 2.2 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EAU88707.1 - 0.0034 17.5 0.0 0.0077 16.4 0.0 1.6 2 0 0 2 2 2 1 LigT like Phosphoesterase DUF1776 PF08643.10 EAU88708.1 - 7.2e-17 61.7 0.0 1.1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ATP-synt_ab PF00006.25 EAU88709.2 - 4.5e-64 216.0 0.2 1.5e-63 214.3 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EAU88709.2 - 0.005 16.1 1.0 0.0099 15.1 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 EAU88709.2 - 0.017 15.5 0.0 0.35 11.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU88709.2 - 0.018 15.4 0.1 0.055 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EAU88709.2 - 0.026 14.5 0.4 0.057 13.3 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EAU88709.2 - 0.027 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EAU88709.2 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EAU88709.2 - 0.05 12.9 0.8 0.11 11.8 0.2 1.8 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.6 EAU88709.2 - 0.062 13.6 0.7 0.26 11.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAU88709.2 - 0.13 12.7 0.2 0.48 10.9 0.2 1.9 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.22 EAU88709.2 - 0.15 12.5 0.0 0.47 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EAU88709.2 - 0.16 12.3 0.1 0.48 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain T3SS_ATPase_C PF18269.1 EAU88709.2 - 0.26 11.2 1.0 1.3 8.9 1.0 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain F-box-like PF12937.7 EAU88710.1 - 0.00035 20.4 2.4 0.0011 18.8 2.4 2.0 1 0 0 1 1 1 1 F-box-like DUF2576 PF10845.8 EAU88710.1 - 0.049 13.3 0.7 0.11 12.1 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) LRR_4 PF12799.7 EAU88710.1 - 0.14 12.6 0.5 1.6e+02 2.9 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Cep57_CLD_2 PF14197.6 EAU88710.1 - 0.2 11.7 1.4 0.47 10.6 1.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 WD40 PF00400.32 EAU88711.2 - 1.5e-65 215.6 5.8 5.6e-10 39.7 0.0 8.3 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU88711.2 - 3.5e-23 81.7 0.1 6.3e-05 23.2 0.0 6.4 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAU88711.2 - 1.6e-10 40.2 0.4 0.1 11.2 0.0 5.3 4 1 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAU88711.2 - 2.4e-05 23.3 0.1 1 8.0 0.0 3.2 2 1 1 3 3 3 3 Nup133 N terminal like Ge1_WD40 PF16529.5 EAU88711.2 - 0.00034 19.7 0.1 0.83 8.6 0.0 3.6 1 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAU88711.2 - 0.0086 16.0 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A bZIP_2 PF07716.15 EAU88711.2 - 0.033 14.3 0.4 0.06 13.4 0.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Pro_CA PF00484.19 EAU88712.2 - 9.8e-29 100.7 3.9 2.9e-25 89.4 2.8 3.4 2 1 0 2 2 2 2 Carbonic anhydrase ESR1_C PF12743.7 EAU88712.2 - 0.015 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Zn_clus PF00172.18 EAU88713.2 - 1.1e-08 35.0 9.5 1.7e-08 34.4 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 EAU88714.2 - 2.5e-41 141.4 0.9 1e-40 139.4 0.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EAU88714.2 - 2.5e-32 111.9 0.1 7.8e-32 110.3 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EAU88714.2 - 6.4e-25 87.2 0.1 1.3e-24 86.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAU88714.2 - 2.8e-14 53.5 0.0 4.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ins_P5_2-kin PF06090.12 EAU88715.1 - 9.4e-90 301.4 0.0 1.1e-89 301.2 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Pkinase PF00069.25 EAU88716.1 - 6.3e-40 137.2 0.0 1e-39 136.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU88716.1 - 6.1e-19 68.3 0.0 3.1e-18 66.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU88716.1 - 3.1e-05 23.5 0.0 5.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EAU88716.1 - 0.002 17.8 0.0 0.48 10.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EAU88716.1 - 0.015 15.3 1.1 0.13 12.2 0.3 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Dishevelled PF02377.15 EAU88717.2 - 0.022 15.2 2.9 0.039 14.4 2.9 1.4 1 0 0 1 1 1 0 Dishevelled specific domain BTB PF00651.31 EAU88717.2 - 0.049 13.9 0.0 0.31 11.3 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.16 EAU88718.2 - 4.7e-32 111.3 31.6 4.7e-32 111.3 31.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU88718.2 - 1.9e-08 33.6 12.5 1.9e-08 33.6 12.5 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter Trp_oprn_chp PF09534.10 EAU88718.2 - 0.13 12.0 0.0 2.1 8.1 0.0 2.8 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2583 PF10762.9 EAU88718.2 - 0.17 12.3 3.2 0.27 11.7 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) SKN1 PF03935.15 EAU88719.1 - 1.2e-194 647.4 0.2 1.4e-194 647.2 0.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EAU88719.1 - 0.0038 16.7 0.0 0.0095 15.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DASH_Dad3 PF08656.10 EAU88720.1 - 1.8e-22 79.2 0.1 2.2e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 WD40 PF00400.32 EAU88721.2 - 4.8e-15 55.7 12.7 0.00044 21.0 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU88721.2 - 5.8e-15 55.4 0.6 4.9e-05 23.5 0.0 4.9 3 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 EAU88721.2 - 0.001 17.9 1.4 0.014 14.2 0.8 2.5 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 EAU88721.2 - 0.0065 16.4 1.4 0.39 10.6 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PAS PF00989.25 EAU88722.2 - 0.048 13.7 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold adh_short_C2 PF13561.6 EAU88723.2 - 3.6e-61 206.7 0.1 4.5e-61 206.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU88723.2 - 8.8e-45 152.6 0.2 2e-44 151.4 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EAU88723.2 - 7.4e-10 39.0 0.3 1.1e-09 38.5 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU88723.2 - 0.00035 20.1 0.0 0.00058 19.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EAU88723.2 - 0.0023 17.1 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein CDPS PF16715.5 EAU88723.2 - 0.17 11.5 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Cyclodipeptide synthase Kinesin PF00225.23 EAU88724.2 - 1.8e-98 329.6 0.0 3.9e-57 193.7 0.0 4.3 5 0 0 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 EAU88724.2 - 2.7e-23 82.6 0.0 1.2e-22 80.5 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding Fib_alpha PF08702.10 EAU88724.2 - 9.4e-05 22.6 5.3 9.4e-05 22.6 5.3 13.0 7 3 7 14 14 14 4 Fibrinogen alpha/beta chain family TolA_bind_tri PF16331.5 EAU88724.2 - 0.0034 17.4 4.2 0.0034 17.4 4.2 14.9 10 6 4 16 16 16 2 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 EAU88724.2 - 0.0069 16.4 8.6 0.0069 16.4 8.6 19.5 10 6 11 21 21 21 5 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 EAU88724.2 - 0.0089 16.4 5.9 0.0089 16.4 5.9 14.3 9 7 8 17 17 17 3 Plant protein of unknown function (DUF641) SASP PF00269.20 EAU88724.2 - 0.075 13.1 2.6 11 6.1 0.1 4.3 3 0 0 3 3 3 0 Small, acid-soluble spore proteins, alpha/beta type Arginase PF00491.21 EAU88725.1 - 1.6e-76 257.5 0.0 1.9e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.21 EAU88726.2 - 3.3e-31 108.8 0.0 4.2e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CwfJ_C_1 PF04677.15 EAU88727.2 - 2.2e-30 105.0 0.0 4.1e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 EAU88727.2 - 6.6e-24 83.4 27.7 5.2e-11 42.1 3.1 4.0 5 0 0 5 5 5 3 Zinc knuckle CwfJ_C_2 PF04676.14 EAU88727.2 - 2.3e-12 47.6 0.0 4.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 EAU88727.2 - 6.7e-10 38.6 15.5 0.00066 19.6 0.4 3.7 3 0 0 3 3 3 3 Zinc knuckle Zn_ribbon_SprT PF17283.2 EAU88727.2 - 0.61 10.1 6.3 13 5.8 0.3 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zf-CCHC_3 PF13917.6 EAU88727.2 - 1.5 8.9 7.3 22 5.1 0.1 3.4 1 1 2 3 3 3 0 Zinc knuckle COesterase PF00135.28 EAU88729.2 - 1.3e-65 222.3 0.0 1.1e-64 219.2 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU88729.2 - 1e-13 51.6 0.0 2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold NIF PF03031.18 EAU88730.2 - 6.2e-24 84.5 0.0 1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TBD PF12845.7 EAU88731.1 - 0.09 12.7 1.1 0.7 9.8 0.4 2.3 1 1 1 2 2 2 0 TBD domain CSN8_PSD8_EIF3K PF10075.9 EAU88732.2 - 4.5e-17 62.4 0.0 6.9e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF5445 PF17520.2 EAU88732.2 - 0.025 14.4 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5445) PCI PF01399.27 EAU88732.2 - 0.051 14.1 0.1 0.09 13.3 0.1 1.4 1 0 0 1 1 1 0 PCI domain tRNA_bind_2 PF13725.6 EAU88732.2 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Possible tRNA binding domain DUF1681 PF07933.14 EAU88733.1 - 4.8e-51 172.3 0.0 6.3e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Glyco_hydro_6 PF01341.17 EAU88734.1 - 1.1e-104 350.4 0.4 1.4e-104 350.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EAU88734.1 - 7.1e-13 48.3 8.6 1.6e-12 47.1 8.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Aminotran_5 PF00266.19 EAU88735.2 - 9.1e-94 314.4 0.0 1.1e-93 314.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EAU88735.2 - 7.3e-08 32.0 0.0 1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EAU88735.2 - 9.2e-05 21.9 0.0 0.00033 20.1 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family RRM_1 PF00076.22 EAU88736.2 - 7.8e-28 96.1 0.0 4.1e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAU88736.2 - 0.00037 20.4 0.0 0.0053 16.7 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EAU88736.2 - 0.0056 16.7 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 EAU88736.2 - 0.069 12.7 0.0 8.8 5.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EAU88736.2 - 0.11 12.6 0.1 6.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 CAP_GLY PF01302.25 EAU88737.2 - 1.4e-15 57.0 0.1 3.7e-15 55.7 0.1 1.7 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 EAU88737.2 - 2.3e-11 43.8 1.9 0.0096 16.3 0.5 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAU88737.2 - 1.6e-10 40.8 0.0 9.8e-07 28.4 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EAU88737.2 - 2.2e-06 27.3 5.5 0.017 14.9 0.8 3.2 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EAU88737.2 - 0.00061 19.6 0.6 21 5.5 1.0 5.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 EAU88737.2 - 5.5 7.9 6.7 61 4.8 0.2 5.0 5 1 0 5 5 5 0 Leucine Rich Repeat ECH_2 PF16113.5 EAU88738.2 - 2e-111 372.7 0.0 2.6e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EAU88738.2 - 7.1e-22 77.9 0.0 2.5e-19 69.6 0.0 2.4 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase TTRAP PF14203.6 EAU88738.2 - 0.13 12.2 0.3 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative tranposon-transfer assisting protein IDO PF01231.18 EAU88739.2 - 6.7e-129 430.4 0.0 7.9e-129 430.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase F-box-like PF12937.7 EAU88739.2 - 0.012 15.5 0.0 7.5 6.5 0.0 2.8 3 0 0 3 3 3 0 F-box-like Rep_fac-A_C PF08646.10 EAU88740.1 - 3e-49 166.5 2.8 1.7e-47 160.9 2.1 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EAU88740.1 - 1.6e-36 124.2 1.7 3.6e-36 123.0 0.3 2.3 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 EAU88740.1 - 7.4e-19 67.7 0.1 1.6e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EAU88740.1 - 1.3e-14 53.9 0.2 1.7e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain DUF5521 PF17659.1 EAU88740.1 - 1.8e-07 29.5 0.1 0.0019 16.2 0.0 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5521) IBR PF01485.21 EAU88740.1 - 0.1 12.8 0.6 0.32 11.2 0.6 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Peptidase_M16_M PF16187.5 EAU88742.1 - 5.1e-97 324.5 1.6 8e-96 320.6 0.1 2.2 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EAU88742.1 - 3.1e-40 137.6 3.6 1e-38 132.7 0.1 3.0 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAU88742.1 - 1.3e-22 80.7 0.1 7e-10 39.2 0.0 3.7 4 0 0 4 4 4 3 Peptidase M16 inactive domain DUF4238 PF14022.6 EAU88742.1 - 0.07 12.6 1.9 0.11 12.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4238) CKS PF01111.19 EAU88743.2 - 8.6e-36 122.0 0.3 1e-35 121.8 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Sec63 PF02889.16 EAU88744.2 - 2.9e-31 108.6 0.0 4.7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EAU88744.2 - 1.7e-20 73.5 0.0 5.1e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAU88744.2 - 1.1e-09 38.5 0.0 1.4e-08 34.9 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAU88744.2 - 2.6e-08 34.2 0.0 1.6e-07 31.6 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EAU88744.2 - 0.0065 16.7 0.0 0.096 13.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAU88744.2 - 0.032 13.3 0.0 0.099 11.7 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EAU88744.2 - 0.043 14.1 0.0 0.19 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain HHH_5 PF14520.6 EAU88744.2 - 0.051 14.2 0.0 0.37 11.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain GAS PF13851.6 EAU88746.1 - 0.00018 20.9 7.6 0.00023 20.6 7.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 EAU88746.1 - 0.0073 15.7 7.5 0.0097 15.3 7.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CorA PF01544.18 EAU88746.1 - 0.0086 15.4 1.6 0.012 15.0 1.6 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ADIP PF11559.8 EAU88746.1 - 0.05 13.7 23.2 0.74 9.9 2.6 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding M PF02370.16 EAU88746.1 - 0.078 13.6 7.4 1.6 9.5 1.7 3.5 2 1 1 3 3 3 0 M protein repeat HALZ PF02183.18 EAU88746.1 - 0.085 13.1 8.8 0.14 12.4 0.4 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF3584 PF12128.8 EAU88746.1 - 0.098 10.2 16.4 0.12 9.8 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NYD-SP28_assoc PF14775.6 EAU88746.1 - 0.1 12.7 0.2 0.1 12.7 0.2 2.8 2 1 0 2 2 2 0 Sperm tail C-terminal domain bZIP_2 PF07716.15 EAU88746.1 - 0.2 11.8 0.2 0.2 11.8 0.2 3.2 2 1 1 3 3 3 0 Basic region leucine zipper UPF0449 PF15136.6 EAU88746.1 - 0.28 11.7 13.6 3.4 8.2 0.2 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Spc24 PF08286.11 EAU88746.1 - 0.35 11.1 12.3 0.46 10.8 0.7 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Tropomyosin_1 PF12718.7 EAU88746.1 - 0.5 10.5 15.6 1.5 9.0 15.6 1.7 1 1 0 1 1 1 0 Tropomyosin like V_ATPase_I PF01496.19 EAU88746.1 - 0.8 7.5 4.8 1.2 7.0 4.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 EAU88746.1 - 0.92 9.0 11.9 1.3 8.6 11.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 EAU88746.1 - 1.1 9.1 8.5 1.7 8.4 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 EAU88746.1 - 1.4 9.1 14.1 2.5 8.3 14.1 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 EAU88746.1 - 2.2 7.3 14.4 3.6 6.6 14.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ax_dynein_light PF10211.9 EAU88746.1 - 4 7.3 16.4 1.7 8.5 13.8 1.8 2 1 0 2 2 2 0 Axonemal dynein light chain FapA PF03961.13 EAU88746.1 - 4.9 5.6 7.0 6.3 5.3 7.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Presenilin PF01080.17 EAU88746.1 - 7.4 5.2 7.3 9.1 4.9 7.3 1.1 1 0 0 1 1 1 0 Presenilin DUF5320 PF17253.2 EAU88746.1 - 8.6 7.5 8.0 11 7.2 2.8 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Exo_endo_phos PF03372.23 EAU88747.2 - 3.5e-08 33.3 0.0 2.4e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_CA PF00484.19 EAU88748.1 - 3.1e-40 138.0 0.0 6.3e-40 137.0 0.0 1.5 1 1 0 1 1 1 1 Carbonic anhydrase Ribosomal_L30_N PF08079.12 EAU88749.1 - 5.5e-28 97.0 18.6 1.3e-27 95.8 18.6 1.7 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EAU88749.1 - 1.8e-18 66.2 0.7 4.2e-18 65.0 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Orf78 PF06024.12 EAU88750.2 - 0.015 15.6 0.0 0.057 13.7 0.0 1.9 2 0 0 2 2 2 0 Orf78 (ac78) EphA2_TM PF14575.6 EAU88750.2 - 0.033 15.1 0.0 0.2 12.6 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 EAU88750.2 - 0.16 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment PepSY_TM PF03929.16 EAU88750.2 - 3.2 7.4 5.8 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 PepSY-associated TM region Aldo_ket_red PF00248.21 EAU88751.1 - 7.6e-39 133.7 0.0 5.7e-38 130.8 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Herpes_gE PF02480.16 EAU88752.2 - 0.011 14.5 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IBV_3C PF03620.13 EAU88752.2 - 0.088 13.3 0.2 0.2 12.2 0.2 1.6 1 0 0 1 1 1 0 IBV 3C protein Amnionless PF14828.6 EAU88752.2 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Amnionless PDGLE PF13190.6 EAU88753.2 - 0.049 13.5 0.2 0.17 11.8 0.2 1.8 1 1 0 1 1 1 0 PDGLE domain Phage_Coat_B PF05356.11 EAU88753.2 - 0.056 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage Coat protein B DUF2207 PF09972.9 EAU88753.2 - 0.067 11.9 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2207 PF09972.9 EAU88754.2 - 0.03 13.1 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 EAU88754.2 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 EAU88754.2 - 0.28 11.1 1.4 0.63 10.0 1.4 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Snf7 PF03357.21 EAU88757.2 - 8.6e-14 51.5 7.7 1.4e-13 50.9 7.7 1.3 1 0 0 1 1 1 1 Snf7 Laminin_II PF06009.12 EAU88757.2 - 0.011 15.7 9.0 0.14 12.2 2.8 2.5 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 EAU88757.2 - 0.26 11.8 2.6 2.5 8.6 0.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EAU88757.2 - 0.47 10.5 4.7 0.47 10.5 2.4 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5321 PF17254.2 EAU88757.2 - 0.49 9.8 4.0 1.1 8.6 4.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5321) Prominin PF05478.11 EAU88757.2 - 0.66 7.9 2.4 0.88 7.4 2.4 1.1 1 0 0 1 1 1 0 Prominin CdvA PF18822.1 EAU88757.2 - 4.2 7.2 11.2 0.46 10.3 5.3 2.5 3 1 0 3 3 3 0 CdvA-like coiled-coil domain COG2 PF06148.11 EAU88757.2 - 4.9 7.2 6.6 0.25 11.4 0.5 2.1 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Cwf_Cwc_15 PF04889.12 EAU88757.2 - 5.4 6.7 7.4 8.6 6.0 7.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HSP9_HSP12 PF04119.12 EAU88758.1 - 2.6e-23 82.1 12.5 2.6e-23 82.1 12.5 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF2673 PF10880.8 EAU88758.1 - 0.43 10.7 5.0 2.9 8.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2673) DUF3484 PF11983.8 EAU88758.1 - 1 10.5 5.0 3.5 8.8 0.8 2.3 1 1 1 2 2 2 0 Membrane-attachment and polymerisation-promoting switch OTU PF02338.19 EAU88759.1 - 0.00022 21.7 0.0 0.00036 21.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease DUF555 PF04475.12 EAU88759.1 - 0.091 13.1 0.0 0.48 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF555) zf-C2H2_2 PF12756.7 EAU88759.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Exo_endo_phos PF03372.23 EAU88760.2 - 8.1e-13 48.4 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U79_P34 PF03064.16 EAU88760.2 - 0.16 11.3 0.3 4.9 6.4 0.0 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 BRCT_2 PF16589.5 EAU88762.1 - 8.7e-06 26.1 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EAU88762.1 - 0.036 14.2 0.3 0.16 12.2 0.3 2.0 1 1 0 1 1 1 0 Rap1 Myb domain Gtr1_RagA PF04670.12 EAU88763.2 - 3.9e-80 268.5 0.1 7.4e-80 267.6 0.1 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EAU88763.2 - 5.8e-05 22.7 0.1 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 Ras family Arf PF00025.21 EAU88763.2 - 9.5e-05 21.9 0.1 0.00018 21.0 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAU88763.2 - 0.00041 20.6 0.0 0.0042 17.3 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EAU88763.2 - 0.07 12.7 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DMRL_synthase PF00885.19 EAU88764.1 - 8e-58 194.3 0.0 9.9e-58 194.0 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.12 EAU88765.1 - 1.2e-23 83.8 3.7 1.2e-23 83.8 3.7 2.8 3 0 0 3 3 3 1 SRP40, C-terminal domain Hydrolase_4 PF12146.8 EAU88766.2 - 4.1e-13 49.2 0.0 5.7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAU88766.2 - 2.7e-11 43.6 0.0 1.7e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU88766.2 - 7.8e-09 36.5 0.1 1e-08 36.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EAU88766.2 - 0.013 15.3 0.1 4 7.2 0.0 2.8 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 EAU88766.2 - 0.015 15.3 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.18 EAU88766.2 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family ATP_bind_3 PF01171.20 EAU88767.2 - 7.5e-30 104.0 0.0 1.1e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 PP-loop family ATP-synt_J PF04911.12 EAU88767.2 - 0.26 10.9 0.8 0.69 9.5 0.1 1.9 2 0 0 2 2 2 0 ATP synthase j chain YTH PF04146.15 EAU88768.2 - 2.8e-40 138.0 2.1 3.1e-40 137.9 0.1 2.1 2 0 0 2 2 2 1 YT521-B-like domain SecIII_SopE_N PF05364.14 EAU88768.2 - 0.031 14.3 0.1 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Pyr_redox_2 PF07992.14 EAU88769.1 - 5.5e-43 147.3 0.0 8.2e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EAU88769.1 - 9.6e-11 40.4 3.0 0.0001 21.6 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EAU88769.1 - 1.1e-08 34.3 0.9 0.0024 17.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Pyr_redox PF00070.27 EAU88769.1 - 2.4e-07 31.2 0.3 7.6e-05 23.2 0.0 3.4 4 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 EAU88769.1 - 8.3e-07 29.4 1.1 1.6e-06 28.4 1.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EAU88769.1 - 0.00061 19.2 1.0 0.031 13.8 0.2 2.4 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.6 EAU88769.1 - 0.003 16.8 0.0 2.7 7.2 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 EAU88769.1 - 0.074 12.9 3.1 3.4 7.6 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain pair NAD_binding_7 PF13241.6 EAU88769.1 - 0.077 13.4 0.1 0.58 10.6 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding SPARC_Ca_bdg PF10591.9 EAU88769.1 - 0.19 12.1 1.5 2.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EAU88769.1 - 0.47 10.4 2.4 43 4.1 0.3 3.1 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand A_deaminase PF00962.22 EAU88771.2 - 3.9e-28 98.7 0.0 1.9e-27 96.4 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EAU88771.2 - 0.0014 18.9 0.0 0.0052 17.1 0.0 2.0 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal KH_1 PF00013.29 EAU88772.2 - 1.4e-42 143.3 8.3 1.2e-15 57.1 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EAU88772.2 - 1.5e-13 50.4 6.6 0.0015 18.3 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EAU88772.2 - 5.4e-05 23.0 0.5 0.64 9.9 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 EAU88772.2 - 0.13 12.4 6.6 3.4 7.8 0.2 3.4 3 0 0 3 3 3 0 NusA-like KH domain Brix PF04427.18 EAU88773.1 - 1.8e-35 122.8 0.0 2.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain Cnn_1N PF07989.11 EAU88775.2 - 0.24 11.6 21.5 0.24 11.6 4.2 4.0 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF1732 PF08340.11 EAU88775.2 - 0.43 10.6 8.2 0.17 11.9 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) YabA PF06156.13 EAU88775.2 - 0.62 10.7 9.9 1.9 9.2 0.2 3.0 2 1 0 2 2 2 0 Initiation control protein YabA HMMR_N PF15905.5 EAU88775.2 - 2.3 7.6 32.1 0.015 14.8 22.4 2.2 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal HALZ PF02183.18 EAU88775.2 - 3.5 7.9 7.8 0.44 10.8 1.7 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper LMBR1 PF04791.16 EAU88775.2 - 6.3 5.6 9.8 0.57 9.0 0.3 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Spc24 PF08286.11 EAU88775.2 - 9.2 6.6 15.7 20 5.5 8.8 3.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Asparaginase PF00710.20 EAU88776.2 - 6.3e-59 198.8 0.0 4e-58 196.1 0.0 2.2 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EAU88776.2 - 1.1e-31 109.4 0.3 2.7e-31 108.1 0.1 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EAU88776.2 - 7e-13 49.0 0.3 3.2e-12 46.8 0.3 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU88776.2 - 6e-11 42.6 0.8 2.3e-06 28.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU88776.2 - 4.5e-09 35.8 0.2 0.014 15.8 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EAU88776.2 - 1.4e-08 34.8 2.9 0.00048 20.5 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EAU88776.2 - 1.7e-08 34.5 0.4 2.6e-06 27.6 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) IF-2B PF01008.17 EAU88779.2 - 3.7e-64 216.6 0.0 4.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family QSOX_Trx1 PF18108.1 EAU88779.2 - 0.037 14.2 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 QSOX Trx-like domain LepA_C PF06421.12 EAU88780.2 - 5.8e-44 148.6 0.2 5.8e-44 148.6 0.2 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 EAU88780.2 - 1e-40 139.4 0.0 1.5e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EAU88780.2 - 1.1e-17 63.8 0.0 2.4e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EAU88780.2 - 3.6e-09 36.9 0.1 8.7e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EAU88780.2 - 2.1e-05 24.5 0.0 5.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EAU88780.2 - 0.00041 20.2 0.2 0.00088 19.1 0.0 1.6 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EAU88780.2 - 0.00071 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EAU88780.2 - 0.00082 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1_Xtn PF16897.5 EAU88780.2 - 0.024 14.7 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SIS_2 PF13580.6 EAU88780.2 - 0.1 12.6 0.0 0.4 10.7 0.0 2.0 1 1 1 2 2 2 0 SIS domain SRPRB PF09439.10 EAU88780.2 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cwf18 PF08315.12 EAU88781.1 - 3.3e-35 121.7 7.4 5.1e-35 121.1 7.4 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Gti1_Pac2 PF09729.9 EAU88782.1 - 5.4e-28 98.3 0.2 1.3e-25 90.6 0.1 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Elongin_A PF06881.11 EAU88783.2 - 9.9e-19 67.8 0.4 1.7e-18 67.0 0.2 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PAP1 PF08601.10 EAU88783.2 - 1.5 8.5 8.3 1.8 8.2 8.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 WD40 PF00400.32 EAU88784.2 - 2.9e-27 94.4 22.1 2e-08 34.8 0.4 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU88784.2 - 1.8e-11 44.2 1.2 0.0059 16.9 0.0 4.4 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4221 PF13970.6 EAU88784.2 - 0.026 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) PQQ_2 PF13360.6 EAU88784.2 - 0.027 14.0 0.1 0.7 9.4 0.0 2.8 1 1 2 3 3 3 0 PQQ-like domain Coatomer_WDAD PF04053.14 EAU88784.2 - 0.038 13.0 0.8 4 6.4 0.0 2.5 2 1 0 2 2 2 0 Coatomer WD associated region Ecl1 PF12855.7 EAU88785.2 - 0.00093 20.4 24.1 0.00093 20.4 24.1 2.8 1 1 1 2 2 2 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 EAU88785.2 - 0.026 15.1 0.6 0.14 12.8 1.0 2.0 2 0 0 2 2 2 0 PLATZ transcription factor PBP1_TM PF14812.6 EAU88785.2 - 0.14 12.6 0.1 0.14 12.6 0.1 2.7 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallothio_Pro PF02069.16 EAU88785.2 - 0.14 12.4 0.9 0.29 11.4 0.9 1.4 1 0 0 1 1 1 0 Prokaryotic metallothionein DUF2116 PF09889.9 EAU88785.2 - 0.47 10.5 1.2 0.9 9.6 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ADP_ribosyl_GH PF03747.14 EAU88786.2 - 1.3e-53 182.6 0.0 2e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DBD_HTH PF18430.1 EAU88786.2 - 0.16 11.8 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding domain Vps54 PF07928.12 EAU88787.2 - 7.7e-51 172.0 3.3 2.4e-50 170.5 3.3 1.9 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 EAU88787.2 - 1.8e-05 24.2 0.2 6.5e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EAU88787.2 - 0.00017 21.4 0.2 0.00034 20.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) PPR PF01535.20 EAU88787.2 - 0.2 12.0 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 PPR repeat DarA_N PF18788.1 EAU88787.2 - 0.27 11.3 1.1 0.45 10.6 0.1 1.8 2 0 0 2 2 2 0 Defence against restriction A N-terminal GST_C_6 PF17171.4 EAU88788.1 - 5e-15 55.1 0.0 1e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 EAU88788.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 EAU88788.1 - 0.0027 17.7 0.0 0.0091 16.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EAU88788.1 - 0.12 13.1 0.0 6.4 7.6 0.0 2.4 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain TRAM_LAG1_CLN8 PF03798.16 EAU88789.1 - 1.7e-29 103.0 16.9 1.7e-29 103.0 16.9 1.7 2 0 0 2 2 2 1 TLC domain NAD_binding_7 PF13241.6 EAU88790.1 - 2.8e-28 98.4 0.0 5.2e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EAU88790.1 - 6.9e-21 73.7 0.4 1.3e-20 72.8 0.4 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EAU88790.1 - 9e-15 53.8 0.1 1.9e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central 2-Hacid_dh_C PF02826.19 EAU88790.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EAU88790.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Torus PF16131.5 EAU88791.1 - 3.3e-08 34.2 0.0 1.3e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 EAU88791.1 - 1.7e-06 27.9 2.8 1.7e-06 27.9 2.8 2.1 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_3 PF15663.5 EAU88791.1 - 0.0014 18.8 0.1 0.0043 17.3 0.1 1.8 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 EAU88791.1 - 0.002 17.9 3.1 0.0058 16.4 3.1 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EAU88791.1 - 0.016 15.1 2.4 0.016 15.1 2.4 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EAU88791.1 - 0.02 15.3 1.9 0.02 15.3 1.9 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_occluded PF16842.5 EAU88791.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_1 PF00076.22 EAU88791.1 - 0.092 12.6 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cript PF10235.9 EAU88791.1 - 0.27 11.8 5.1 2.8 8.6 1.3 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT LEA_2 PF03168.13 EAU88793.2 - 0.00041 20.9 0.1 0.0026 18.3 0.0 2.1 2 0 0 2 2 2 1 Late embryogenesis abundant protein Vac7 PF12751.7 EAU88793.2 - 0.0016 17.9 0.1 0.0033 16.9 0.1 1.4 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 Pkinase PF00069.25 EAU88797.2 - 2.4e-26 92.7 0.0 2.9e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU88797.2 - 9.2e-13 48.1 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU88797.2 - 1.7e-07 30.4 0.0 2.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU88797.2 - 0.029 14.3 0.0 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Vac_ImportDeg PF09783.9 EAU88798.2 - 1.3e-54 184.4 0.0 2.9e-54 183.3 0.0 1.6 1 1 0 1 1 1 1 Vacuolar import and degradation protein MFS_1 PF07690.16 EAU88799.2 - 1.8e-37 129.1 30.7 1.3e-35 123.0 32.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EAU88799.2 - 8.7e-10 37.6 9.9 1.8e-09 36.6 9.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EAU88799.2 - 6.8e-08 31.8 23.4 4e-07 29.3 8.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.8 EAU88799.2 - 0.00025 19.8 2.7 0.057 12.1 0.0 2.5 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like DUF2754 PF10953.8 EAU88799.2 - 0.07 13.4 2.7 0.081 13.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) DUF3185 PF11381.8 EAU88799.2 - 2.6 8.1 12.3 2.5 8.2 2.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Ras PF00071.22 EAU88800.1 - 2.9e-50 170.0 0.0 3.4e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU88800.1 - 3.1e-30 104.9 0.0 4.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU88800.1 - 5.5e-10 39.0 0.0 7.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAU88800.1 - 0.00028 20.3 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU88800.1 - 0.0012 18.9 0.0 0.0021 18.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EAU88800.1 - 0.013 14.7 1.8 0.84 8.7 0.2 2.6 2 1 0 2 2 2 0 G-protein alpha subunit Pox_A32 PF04665.12 EAU88800.1 - 0.024 14.1 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 EAU88800.1 - 0.026 14.9 0.1 0.21 12.0 0.1 2.1 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EAU88800.1 - 0.027 14.0 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF5118 PF17162.4 EAU88800.1 - 0.037 13.9 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 EAU88800.1 - 0.05 13.3 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAU88800.1 - 0.076 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EAU88800.1 - 0.089 12.7 0.0 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 EAU88800.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EAU88800.1 - 0.13 12.4 0.2 0.22 11.7 0.2 1.3 1 0 0 1 1 1 0 AAA domain STAS PF01740.21 EAU88800.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 STAS domain Ribosomal_L26 PF16906.5 EAU88802.1 - 1.1e-37 128.3 3.8 1.6e-37 127.8 3.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EAU88802.1 - 1.8e-09 37.2 6.7 2.2e-09 37.0 5.6 1.7 2 0 0 2 2 2 1 KOW motif ATP-synt_D PF01813.17 EAU88803.1 - 1.6e-69 233.7 1.9 2.4e-69 233.1 1.9 1.2 1 0 0 1 1 1 1 ATP synthase subunit D XAP5 PF04921.14 EAU88804.2 - 3e-89 299.1 1.4 3e-89 299.1 1.4 2.2 1 1 1 2 2 2 1 XAP5, circadian clock regulator Argos PF11581.8 EAU88804.2 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Antagonist of EGFR signalling, Argos Ribosomal_S13 PF00416.22 EAU88805.2 - 4.1e-19 69.2 0.0 8.7e-11 42.3 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 IMS_HHH PF11798.8 EAU88805.2 - 0.019 15.3 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 IMS family HHH motif FbpA PF05833.11 EAU88805.2 - 0.036 12.8 0.1 0.12 11.1 0.0 1.7 1 1 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) DNA_pol_lambd_f PF10391.9 EAU88805.2 - 0.13 12.1 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda TRAPP PF04051.16 EAU88806.2 - 6e-38 129.8 0.0 7.2e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WBS_methylT PF12589.8 EAU88807.1 - 2e-24 86.1 11.2 3.9e-24 85.2 11.2 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EAU88807.1 - 4.1e-09 37.0 0.0 9.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU88807.1 - 1.9e-07 31.7 0.0 3.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU88807.1 - 6.4e-05 23.6 0.3 0.00028 21.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU88807.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU88807.1 - 0.0023 17.7 0.0 0.0061 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EAU88807.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase BCS1_N PF08740.11 EAU88808.2 - 6.7e-51 172.9 5.3 9e-51 172.5 5.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EAU88808.2 - 9.7e-18 64.9 0.0 2e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU88808.2 - 0.00023 21.6 0.0 0.00079 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EAU88808.2 - 0.00028 20.5 0.0 0.0016 18.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EAU88808.2 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EAU88808.2 - 0.013 16.0 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EAU88808.2 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 EAU88808.2 - 0.018 15.1 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAU88808.2 - 0.021 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EAU88808.2 - 0.024 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAU88808.2 - 0.033 14.3 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAU88808.2 - 0.038 13.7 0.0 0.091 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EAU88808.2 - 0.046 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 EAU88808.2 - 0.067 13.7 0.0 0.16 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 EAU88808.2 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EAU88808.2 - 0.097 12.9 0.0 0.27 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP39 PF14980.6 EAU88808.2 - 0.11 12.3 0.2 0.89 9.5 0.1 2.5 2 0 0 2 2 2 0 TIP39 peptide ABC_tran PF00005.27 EAU88808.2 - 0.12 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 EAU88808.2 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_3 PF14606.6 EAU88808.2 - 0.15 12.1 0.0 18 5.4 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TsaE PF02367.17 EAU88808.2 - 0.15 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EAU88808.2 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EAU88808.2 - 0.17 11.8 0.0 1.7 8.6 0.0 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain Ank_2 PF12796.7 EAU88809.1 - 1e-16 61.3 0.0 2.5e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DnaJ PF00226.31 EAU88809.1 - 1.3e-14 54.0 0.0 5.3e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Ank_4 PF13637.6 EAU88809.1 - 7.3e-09 36.0 0.0 2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU88809.1 - 3.7e-08 33.0 0.0 0.029 14.9 0.0 3.3 4 0 0 4 4 2 2 Ankyrin repeat Ank_5 PF13857.6 EAU88809.1 - 6e-06 26.4 0.0 2.4e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EAU88809.1 - 6.1e-06 26.4 0.0 0.29 11.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat DUF3523 PF12037.8 EAU88809.1 - 0.01 15.2 19.0 0.017 14.5 19.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) CAF-1_p150 PF11600.8 EAU88809.1 - 0.45 10.2 29.8 0.98 9.1 29.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TAF4 PF05236.14 EAU88809.1 - 1.1 8.9 18.9 0.038 13.7 12.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Cdh1_DBD_1 PF18196.1 EAU88809.1 - 3.1 8.2 13.9 9.5 6.6 13.9 1.9 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 FAM178 PF14816.6 EAU88809.1 - 3.1 6.7 8.0 4.7 6.1 8.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 V_ATPase_I PF01496.19 EAU88809.1 - 3.6 5.4 5.3 6.2 4.6 5.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 EAU88809.1 - 5.2 6.8 17.3 0.29 10.9 9.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 EAU88809.1 - 7.4 6.5 8.4 2.2 8.3 1.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ubiquitin PF00240.23 EAU88811.1 - 7.5e-11 41.6 0.2 1.3e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EAU88811.1 - 1.2e-05 25.0 0.3 2.3e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUSP PF06337.12 EAU88811.1 - 0.00026 21.5 0.0 0.00052 20.6 0.0 1.5 1 0 0 1 1 1 1 DUSP domain Ubiquitin_4 PF18036.1 EAU88811.1 - 0.007 16.4 0.4 2.2 8.4 0.2 2.9 3 0 0 3 3 3 2 Ubiquitin-like domain zf-RanBP PF00641.18 EAU88811.1 - 0.0098 15.2 2.1 0.022 14.1 2.1 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UN_NPL4 PF11543.8 EAU88811.1 - 0.088 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 LUC7 PF03194.15 EAU88813.2 - 2.1e-70 237.3 6.2 2.6e-70 237.0 6.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Phlebovirus_NSM PF07246.11 EAU88813.2 - 0.041 13.2 1.4 0.056 12.8 1.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3418 PF11898.8 EAU88813.2 - 0.053 12.2 0.5 0.072 11.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) DUF3367 PF11847.8 EAU88813.2 - 0.25 9.1 0.1 0.31 8.9 0.1 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Gaa1 PF04114.14 EAU88814.2 - 3.8e-76 257.1 12.5 7.9e-49 167.0 8.0 3.0 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component TAFII55_N PF04658.13 EAU88815.2 - 9.9e-56 187.9 1.0 9.9e-56 187.9 1.0 2.3 2 0 0 2 2 2 1 TAFII55 protein conserved region Tom37 PF10568.9 EAU88816.1 - 1.9e-29 102.5 0.0 3.9e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EAU88816.1 - 8.2e-09 36.1 0.0 2.9e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EAU88816.1 - 7.6e-07 28.8 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAU88816.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glyco_hydro_30 PF02055.16 EAU88816.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain NPR2 PF06218.11 EAU88817.2 - 1.7e-85 287.4 13.3 2.2e-66 224.4 9.5 3.9 1 1 1 2 2 2 2 Nitrogen permease regulator 2 ThiF PF00899.21 EAU88818.1 - 3e-63 213.4 0.0 4.1e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EAU88818.1 - 7.8e-29 99.7 0.7 1.2e-28 99.0 0.7 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EAU88818.1 - 0.0059 16.7 0.2 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EAU88818.1 - 0.033 13.8 0.1 0.063 12.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 EAU88818.1 - 0.056 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 EAU88818.1 - 0.14 12.8 0.1 0.33 11.6 0.1 1.6 1 0 0 1 1 1 0 PglD N-terminal domain OGG_N PF07934.12 EAU88821.2 - 1.5e-33 115.5 0.0 2.2e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EAU88821.2 - 2.3e-17 63.4 0.0 5.6e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EAU88821.2 - 0.031 14.1 0.2 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Transket_pyr PF02779.24 EAU88822.2 - 5e-40 137.1 0.1 7.3e-40 136.5 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EAU88822.2 - 6.7e-28 97.1 0.0 3.1e-27 94.9 0.0 2.1 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.32 EAU88823.2 - 1.7e-06 28.6 14.0 0.024 15.5 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU88823.2 - 4.9e-06 26.7 0.0 0.29 11.5 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EAU88823.2 - 0.00097 17.8 0.0 0.0039 15.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain BRX_assoc PF16627.5 EAU88823.2 - 1.5 9.0 7.0 1 9.5 3.9 2.3 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain CNDH2_C PF16858.5 EAU88824.1 - 0.0028 17.6 1.1 0.004 17.1 1.1 1.2 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Apc15p PF05841.11 EAU88824.1 - 0.0049 17.7 0.0 0.0082 16.9 0.0 1.3 1 0 0 1 1 1 1 Apc15p protein Na_trans_assoc PF06512.13 EAU88824.1 - 0.056 13.7 9.6 0.077 13.3 9.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated EMP24_GP25L PF01105.24 EAU88824.1 - 0.1 12.5 0.6 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MYCBPAP PF14646.6 EAU88824.1 - 0.14 11.1 2.1 0.15 10.9 2.1 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family MTHFR PF02219.17 EAU88825.2 - 1.4e-74 251.0 0.0 1.8e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ras PF00071.22 EAU88826.2 - 2.4e-59 199.5 0.5 3.1e-59 199.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU88826.2 - 1.9e-37 128.1 0.1 3.6e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU88826.2 - 2.8e-16 59.4 0.2 3.6e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAU88826.2 - 5.7e-07 29.1 0.1 1.3e-06 27.9 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EAU88826.2 - 1.4e-06 28.0 0.6 1.7e-05 24.5 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAU88826.2 - 7.2e-06 25.5 0.7 9.6e-06 25.1 0.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU88826.2 - 1.5e-05 25.0 0.1 4e-05 23.7 0.1 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU88826.2 - 5.7e-05 23.1 0.1 0.015 15.2 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EAU88826.2 - 0.00045 19.8 0.5 0.017 14.6 0.5 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EAU88826.2 - 0.0068 16.2 0.2 0.016 15.0 0.1 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 EAU88826.2 - 0.043 13.2 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Dynamin_N PF00350.23 EAU88826.2 - 0.059 13.4 0.0 2.4 8.2 0.0 2.5 2 1 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 EAU88826.2 - 0.074 12.8 2.0 0.46 10.2 2.0 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CPT PF07931.12 EAU88826.2 - 0.075 12.9 0.0 0.15 11.9 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TAP42 PF04177.12 EAU88827.1 - 6.2e-83 278.6 1.7 7.1e-83 278.4 1.7 1.0 1 0 0 1 1 1 1 TAP42-like family DUF572 PF04502.13 EAU88827.1 - 4.5 6.8 12.5 7.7 6.0 12.4 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) peroxidase PF00141.23 EAU88828.2 - 2.7e-24 86.2 0.0 4.5e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase POT1PC PF16686.5 EAU88829.2 - 5.2e-16 58.9 2.1 1.2e-08 34.9 0.1 4.3 3 2 0 3 3 3 2 ssDNA-binding domain of telomere protection protein Peptidase_M28 PF04389.17 EAU88833.1 - 2.4e-38 131.8 0.0 4.2e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 YebG PF07130.12 EAU88833.1 - 0.13 12.2 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 YebG protein Sybindin PF04099.12 EAU88834.1 - 3.2e-39 134.1 0.0 3.7e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EAU88834.1 - 1.4e-08 34.9 0.0 1.6e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region TATR PF03430.13 EAU88834.1 - 0.24 9.8 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator HORMA PF02301.18 EAU88835.2 - 1.9e-28 99.5 0.0 2.3e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 HORMA domain HORMA PF02301.18 EAU88836.2 - 2e-21 76.5 0.0 3.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 HORMA domain TP2 PF01254.18 EAU88836.2 - 3.3 8.3 5.6 1.5 9.4 2.3 2.1 2 0 0 2 2 2 0 Nuclear transition protein 2 PUL PF08324.11 EAU88837.2 - 6.4e-50 169.9 0.1 8.8e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EAU88837.2 - 1.4e-44 151.0 0.6 3.1e-44 149.8 0.6 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EAU88837.2 - 3.1e-30 103.8 17.6 1.1e-07 32.4 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 EAU88837.2 - 0.00036 20.5 0.0 0.21 11.7 0.0 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region His_Phos_1 PF00300.22 EAU88838.2 - 2.3e-39 135.1 0.0 3.2e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NdhN PF11909.8 EAU88838.2 - 0.09 12.4 0.0 9.5 5.9 0.0 2.3 2 0 0 2 2 2 0 NADH-quinone oxidoreductase cyanobacterial subunit N DUF768 PF05589.11 EAU88838.2 - 0.11 12.6 0.1 8.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF768) RTC PF01137.21 EAU88839.2 - 9.2e-40 136.2 0.0 1.8e-28 99.3 0.0 2.0 1 1 1 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EAU88839.2 - 2.2e-39 134.1 0.0 3.3e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain BMFP PF04380.13 EAU88841.2 - 0.0029 18.1 4.9 0.018 15.5 0.3 3.2 2 1 1 3 3 3 1 Membrane fusogenic activity Sds3 PF08598.11 EAU88841.2 - 0.02 14.9 3.1 0.033 14.2 3.1 1.4 1 1 0 1 1 1 0 Sds3-like UPF0154 PF03672.13 EAU88841.2 - 0.042 13.9 0.2 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF445 PF04286.12 EAU88841.2 - 0.056 13.2 2.9 0.078 12.8 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4164 PF13747.6 EAU88841.2 - 0.065 13.5 6.9 0.27 11.5 0.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Fungal_TACC PF12709.7 EAU88841.2 - 0.068 13.6 4.9 5.6 7.5 0.3 3.3 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Prenyltransf PF01255.19 EAU88841.2 - 0.068 12.7 0.1 0.12 11.9 0.1 1.4 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Rnk_N PF14760.6 EAU88841.2 - 0.086 13.3 0.3 0.086 13.3 0.3 2.7 4 0 0 4 4 4 0 Rnk N-terminus DUF4407 PF14362.6 EAU88841.2 - 0.2 11.0 4.4 0.64 9.3 4.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HSCB_C PF07743.13 EAU88841.2 - 0.22 12.1 7.7 13 6.4 0.2 3.4 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain PEP-utilisers_N PF05524.13 EAU88841.2 - 0.56 10.4 5.4 3.6 7.8 0.4 2.9 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Cortex-I_coil PF09304.10 EAU88841.2 - 0.57 10.4 6.1 0.13 12.5 0.5 2.3 1 1 0 2 2 2 0 Cortexillin I, coiled coil FlgN PF05130.12 EAU88841.2 - 0.73 10.3 7.0 1.2 9.6 2.4 2.3 2 0 0 2 2 2 0 FlgN protein G-gamma PF00631.22 EAU88842.2 - 6.9e-23 80.4 0.0 7.7e-23 80.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.22 EAU88843.2 - 2.9e-23 81.6 0.0 3.2e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 GGL domain DUF5540 PF17694.1 EAU88843.2 - 0.048 14.2 0.1 0.065 13.7 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5540) Cu_bind_like PF02298.17 EAU88846.1 - 0.0076 16.2 0.3 0.025 14.6 0.3 1.7 1 1 0 1 1 1 1 Plastocyanin-like domain Myotub-related PF06602.14 EAU88847.2 - 2.1e-147 490.7 0.1 2.7e-147 490.3 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain HTH_29 PF13551.6 EAU88847.2 - 0.0083 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix DSPc PF00782.20 EAU88847.2 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAU88847.2 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF3958 PF13125.6 EAU88847.2 - 1.5 9.1 4.4 0.81 9.9 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) S-AdoMet_synt_C PF02773.16 EAU88848.1 - 1.8e-67 225.6 0.6 4.9e-67 224.2 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EAU88848.1 - 2.2e-48 163.5 0.0 4e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EAU88848.1 - 3.9e-45 152.6 0.1 7.8e-45 151.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EAU88848.1 - 0.011 14.6 0.5 0.17 10.7 0.1 2.2 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) GATase_6 PF13522.6 EAU88849.2 - 1e-11 45.2 0.0 1.9e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EAU88849.2 - 2.2e-11 43.5 0.1 3.8e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.6 EAU88849.2 - 2.9e-10 40.1 0.0 5.3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EAU88849.2 - 1.7e-05 23.9 0.0 7.4e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II HIT PF01230.23 EAU88850.2 - 8.5e-25 87.4 0.0 1.3e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EAU88850.2 - 8.5e-08 32.7 0.0 1.3e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EAU88850.2 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Glyoxal_oxid_N PF07250.11 EAU88851.2 - 2.7e-35 121.7 0.0 2.5e-34 118.5 0.0 2.4 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EAU88851.2 - 2.5e-24 85.4 0.0 5.6e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Pkinase_Tyr PF07714.17 EAU88854.1 - 2.8e-46 157.9 0.0 5.5e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU88854.1 - 4.2e-45 154.2 0.0 7.2e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAP PF02037.27 EAU88854.1 - 0.043 13.6 0.2 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 SAP domain DUF3835 PF12927.7 EAU88855.2 - 0.012 16.4 3.5 0.012 16.4 3.5 5.3 4 2 1 5 5 5 0 Domain of unknown function (DUF3835) DUF724 PF05266.14 EAU88855.2 - 0.34 10.7 12.8 0.79 9.5 12.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA PF00004.29 EAU88856.2 - 2.2e-07 31.4 0.1 9.3e-07 29.3 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAU88856.2 - 1.8e-05 24.6 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EAU88856.2 - 7.1e-05 22.5 0.2 0.17 11.4 0.0 2.8 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EAU88856.2 - 0.00062 20.2 0.0 0.0043 17.5 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EAU88856.2 - 0.00075 19.5 0.1 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EAU88856.2 - 0.0021 18.4 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 EAU88856.2 - 0.0091 16.3 0.0 0.076 13.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAU88856.2 - 0.047 13.0 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 EAU88856.2 - 0.049 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 EAU88856.2 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EAU88856.2 - 0.067 13.3 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAU88856.2 - 0.074 13.0 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EAU88856.2 - 0.13 12.8 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAU88856.2 - 0.17 11.8 0.1 0.4 10.6 0.0 1.6 2 0 0 2 2 2 0 NTPase Hydrophobin PF01185.18 EAU88857.1 - 5.6e-18 65.4 7.2 6.9e-18 65.1 7.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Utp21 PF04192.12 EAU88858.2 - 1.1e-67 228.0 3.3 1.8e-67 227.3 3.3 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EAU88858.2 - 3.3e-17 62.6 0.0 7.8e-05 22.9 0.0 6.0 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU88858.2 - 2.4e-16 59.8 10.2 0.008 17.0 0.0 8.7 10 0 0 10 10 10 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EAU88858.2 - 0.15 11.0 0.0 27 3.6 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SRPRB PF09439.10 EAU88859.1 - 2.5e-25 89.0 0.0 3.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EAU88859.1 - 4.3e-13 49.1 0.0 5.8e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAU88859.1 - 5.4e-07 29.8 0.0 9.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAU88859.1 - 7.1e-07 29.3 0.0 1.7e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAU88859.1 - 3e-06 26.8 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAU88859.1 - 6.7e-06 25.8 0.0 0.00075 19.1 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EAU88859.1 - 0.00043 19.6 0.0 0.75 8.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 EAU88859.1 - 0.0057 16.2 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EAU88859.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EAU88859.1 - 0.026 13.9 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Bacterial TniB protein ATP_bind_1 PF03029.17 EAU88859.1 - 0.031 14.1 0.1 0.096 12.4 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 EAU88859.1 - 0.034 13.7 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ApbE PF02424.15 EAU88859.1 - 0.081 12.4 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 ApbE family FeoB_N PF02421.18 EAU88859.1 - 0.1 12.1 0.0 0.27 10.8 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EAU88859.1 - 0.15 12.3 0.2 0.42 10.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EAU88860.2 - 2.6e-29 102.2 32.5 1.4e-28 99.9 32.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EAU88860.2 - 0.00014 21.3 5.7 0.00014 21.3 5.7 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB CLP1_P PF16575.5 EAU88861.1 - 8.4e-33 113.8 0.0 2.8e-32 112.0 0.0 1.9 2 1 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EAU88861.1 - 1.7e-30 105.1 0.0 2.8e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EAU88861.1 - 4e-28 98.2 0.0 6.6e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_18 PF13238.6 EAU88861.1 - 0.073 13.6 0.0 0.41 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1713 PF08213.11 EAU88862.2 - 0.0021 17.9 11.2 0.0032 17.4 11.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) UQ_con PF00179.26 EAU88863.2 - 4e-50 169.1 0.0 4.5e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAU88863.2 - 0.00011 22.0 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EAU88863.2 - 0.03 14.6 0.6 0.045 14.0 0.6 1.6 1 1 0 1 1 1 0 RWD domain DNA_methylase PF00145.17 EAU88864.2 - 2.5e-47 161.9 0.0 4e-46 157.9 0.0 2.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EAU88864.2 - 7.2e-13 48.5 0.0 6.7e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 EAU88864.2 - 1.5e-09 38.0 0.0 2.5e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain MCM PF00493.23 EAU88865.2 - 6.4e-107 355.7 0.0 1.2e-106 354.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAU88865.2 - 3.6e-30 104.4 0.4 7.2e-30 103.4 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAU88865.2 - 3.2e-19 69.1 0.6 1e-18 67.5 0.6 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAU88865.2 - 1.3e-17 64.3 1.7 1.3e-17 64.3 1.7 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAU88865.2 - 4.7e-08 32.7 0.1 8.7e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAU88865.2 - 4.9e-08 33.1 0.0 8.9e-06 25.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EAU88865.2 - 0.015 15.1 0.1 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 AAA lid domain AAA_3 PF07726.11 EAU88865.2 - 0.024 14.5 0.0 0.09 12.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EAU88865.2 - 0.052 14.2 3.1 0.057 14.1 0.5 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 EAU88865.2 - 0.1 12.3 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 EAU88865.2 - 0.14 12.5 3.3 4.2 7.7 0.1 3.6 2 1 0 2 2 2 0 AAA ATPase domain NMT_C PF02799.15 EAU88866.1 - 1.6e-79 266.3 0.0 3e-79 265.4 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EAU88866.1 - 1e-77 259.4 0.0 1.6e-77 258.9 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EAU88866.1 - 6.6e-05 23.0 0.0 0.00021 21.4 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU88866.1 - 0.002 18.4 0.0 0.0052 17.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF3772 PF12607.8 EAU88867.1 - 6.9 6.5 6.4 24 4.8 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3772) KorB PF08535.10 EAU88868.2 - 0.16 12.1 0.0 0.27 11.3 0.0 1.4 1 1 0 1 1 1 0 KorB domain Toxin_19 PF08088.12 EAU88869.2 - 0.093 12.9 6.2 0.078 13.1 4.7 1.6 1 1 0 1 1 1 0 Conotoxin I-superfamily DUF1664 PF07889.12 EAU88874.1 - 0.063 13.3 0.0 4.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase_fungal PF17667.1 EAU88875.2 - 2e-36 125.7 0.0 5e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU88875.2 - 1.6e-07 31.0 0.0 7.4e-07 28.8 0.0 2.0 3 0 0 3 3 3 1 Protein kinase domain F-box-like PF12937.7 EAU88876.2 - 4.6e-06 26.4 0.0 0.021 14.7 0.0 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EAU88876.2 - 0.07 13.0 0.3 11 6.0 0.0 2.9 2 0 0 2 2 2 0 F-box domain Hexapep PF00132.24 EAU88877.1 - 0.00014 21.4 15.5 0.59 9.9 0.3 4.1 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EAU88877.1 - 0.21 11.4 11.6 0.073 12.8 2.7 2.7 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase ANAPC4_WD40 PF12894.7 EAU88879.1 - 0.0056 16.9 0.3 0.98 9.8 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EAU88879.1 - 0.038 14.5 5.4 0.65 10.6 0.4 4.3 5 0 0 5 5 5 0 PQQ-like domain PQQ PF01011.21 EAU88879.1 - 0.12 12.3 0.5 8.9 6.4 0.0 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat F-box PF00646.33 EAU88880.2 - 0.016 15.1 0.3 0.056 13.4 0.3 1.9 1 0 0 1 1 1 0 F-box domain DUF1800 PF08811.11 EAU88880.2 - 0.15 11.1 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) WCCH PF03716.14 EAU88880.2 - 0.15 11.8 5.8 0.049 13.3 0.7 2.7 2 0 0 2 2 2 0 WCCH motif RdRP PF05183.12 EAU88888.2 - 4.8e-163 544.0 0.0 6.1e-163 543.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3492 PF11997.8 EAU88888.2 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) PhoLip_ATPase_C PF16212.5 EAU88889.2 - 3.8e-71 239.8 26.8 3.8e-71 239.8 26.8 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAU88889.2 - 5.2e-16 58.1 5.0 4.6e-15 55.1 5.0 2.5 1 1 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EAU88889.2 - 4.9e-13 49.9 0.3 2.5e-06 27.9 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAU88889.2 - 3.4e-10 39.9 0.0 1.3e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU88889.2 - 2e-05 24.5 0.9 0.0052 16.6 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAU88889.2 - 2.9e-05 23.7 0.0 8e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAU88889.2 - 0.044 13.5 13.3 0.044 13.5 9.9 2.7 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus SesA PF17107.5 EAU88889.2 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Septin PF00735.18 EAU88890.1 - 7.2e-114 379.8 0.8 8.6e-114 379.6 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EAU88890.1 - 2e-09 37.5 0.1 5.1e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU88890.1 - 6.5e-08 32.2 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EAU88890.1 - 1.3e-07 31.7 0.2 3e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EAU88890.1 - 1.5e-06 27.9 0.4 0.00046 19.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAU88890.1 - 4.3e-05 23.6 0.3 0.16 12.0 0.2 2.5 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 EAU88890.1 - 0.00034 19.9 0.0 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EAU88890.1 - 0.00074 19.9 0.0 0.0013 19.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EAU88890.1 - 0.001 19.6 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.12 EAU88890.1 - 0.0012 18.6 0.1 0.27 11.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Gtr1_RagA PF04670.12 EAU88890.1 - 0.0012 18.3 0.2 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region T2SSE PF00437.20 EAU88890.1 - 0.0061 15.7 0.1 0.011 14.8 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 EAU88890.1 - 0.0063 16.6 0.2 0.052 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAU88890.1 - 0.0071 15.9 0.1 0.047 13.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 EAU88890.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EAU88890.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ras PF00071.22 EAU88890.1 - 0.013 15.2 0.2 0.063 12.9 0.1 2.1 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 EAU88890.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EAU88890.1 - 0.024 14.9 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EAU88890.1 - 0.035 13.3 0.4 0.053 12.7 0.4 1.6 1 1 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.13 EAU88890.1 - 0.04 13.1 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EAU88890.1 - 0.088 12.8 0.2 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 EAU88890.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MCM PF00493.23 EAU88890.1 - 0.12 11.5 0.0 0.39 9.8 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain AAA_23 PF13476.6 EAU88890.1 - 2.1 8.8 4.4 5.3 7.5 4.5 1.8 1 1 0 1 1 1 0 AAA domain Aha1_N PF09229.11 EAU88891.2 - 9.9e-32 110.0 0.2 1.5e-31 109.4 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EAU88891.2 - 4e-13 49.7 0.1 8.1e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.9 EAU88891.2 - 0.00032 21.0 4.5 0.015 15.5 0.5 2.3 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport DEC-1_N PF04625.13 EAU88891.2 - 0.15 11.0 5.6 0.21 10.6 5.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Terpene_synth_C PF03936.16 EAU88892.1 - 6.6e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 EAU88892.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 Sporulation initiation phospho-transferase B, C-terminal CAP_N PF01213.19 EAU88892.1 - 0.0072 15.8 1.1 0.011 15.2 1.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal TRI5 PF06330.11 EAU88892.1 - 0.024 13.5 0.1 0.051 12.4 0.1 1.5 2 0 0 2 2 2 0 Trichodiene synthase (TRI5) Mito_fiss_reg PF05308.11 EAU88892.1 - 0.17 12.0 1.0 0.28 11.2 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 EAU88892.1 - 0.5 10.4 3.3 0.89 9.6 3.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3429 PF11911.8 EAU88893.2 - 4e-42 143.9 11.9 5.2e-42 143.5 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Gln-synt_C PF00120.24 EAU88896.2 - 1.5e-71 241.2 0.0 5.6e-71 239.3 0.0 1.9 2 1 0 2 2 2 1 Glutamine synthetase, catalytic domain Pkinase_fungal PF17667.1 EAU88898.2 - 2e-47 161.9 0.0 1.1e-46 159.4 0.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU88898.2 - 1.8e-05 24.2 0.0 3.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH3_9 PF14604.6 EAU88901.2 - 1.6e-15 56.7 0.0 2.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAU88901.2 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAU88901.2 - 0.00025 20.7 0.0 0.00044 19.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Chromo PF00385.24 EAU88903.2 - 2e-08 34.0 3.2 4.3e-08 33.0 3.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.7 EAU88904.2 - 1.6e-07 31.1 0.0 5.8e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU88907.2 - 5.4e-08 32.6 1.1 2.5e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU88907.2 - 0.084 12.8 0.5 22 5.1 0.0 3.3 3 0 0 3 3 3 0 F-box domain tRNA_Me_trans PF03054.16 EAU88908.2 - 7.7e-104 347.3 0.0 8.9e-104 347.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EAU88908.2 - 0.021 14.0 0.1 0.93 8.6 0.0 2.5 2 1 0 2 2 2 0 NAD synthase ThiI PF02568.14 EAU88908.2 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) CENP-C_C PF11699.8 EAU88909.1 - 2e-24 85.6 0.0 3.1e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EAU88909.1 - 7.6e-05 22.4 0.0 0.00021 20.9 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EAU88909.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Cupin CE2_N PF17996.1 EAU88910.1 - 0.0013 18.7 0.0 0.85 9.6 0.0 2.6 3 0 0 3 3 3 2 Carbohydrate esterase 2 N-terminal Adeno_E3_CR2 PF02439.15 EAU88910.1 - 0.02 14.6 0.7 0.032 14.0 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Phage_holin_2_1 PF04971.12 EAU88910.1 - 0.099 12.7 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S SH3_1 PF00018.28 EAU88911.1 - 8e-12 44.6 0.7 1.4e-06 27.8 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EAU88911.1 - 8.6e-09 35.1 0.5 0.0027 17.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EAU88911.1 - 5.3e-06 26.0 0.4 4.6e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.11 EAU88911.1 - 0.0011 19.3 2.9 0.1 12.9 0.3 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain SH3_4 PF06347.13 EAU88911.1 - 0.013 15.3 0.1 0.033 14.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain LSM14 PF12701.7 EAU88913.1 - 1.8e-25 88.9 0.0 3e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EAU88913.1 - 4.2e-12 46.9 2.2 1.4e-11 45.2 0.0 2.3 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 EAU88913.1 - 0.00064 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 EAU88913.1 - 0.0027 17.8 20.2 0.003 17.6 20.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3292 PF11696.8 EAU88913.1 - 0.37 9.1 6.3 0.54 8.6 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) F-box-like PF12937.7 EAU88916.2 - 2e-06 27.6 1.2 4.8e-06 26.4 1.2 1.7 1 0 0 1 1 1 1 F-box-like Med31 PF05669.12 EAU88916.2 - 0.087 12.8 0.2 0.19 11.7 0.2 1.5 1 0 0 1 1 1 0 SOH1 Syndecan PF01034.20 EAU88918.2 - 0.35 10.8 0.6 0.61 10.0 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain TrkH PF02386.16 EAU88919.1 - 0.16 10.4 5.0 0.26 9.7 5.0 1.3 1 0 0 1 1 1 0 Cation transport protein Gram_pos_anchor PF00746.21 EAU88920.2 - 0.12 12.3 0.3 0.29 11.1 0.3 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif NAD_binding_10 PF13460.6 EAU88922.1 - 4.1e-15 56.2 0.0 8.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 EAU88922.1 - 5.8e-05 22.6 0.0 7.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU88922.1 - 7.1e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EAU88922.1 - 0.001 18.6 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EAU88922.1 - 0.0023 17.3 0.0 0.0045 16.3 0.0 1.5 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.19 EAU88922.1 - 0.064 12.0 0.0 1.2 7.8 0.0 2.4 2 1 1 3 3 3 0 Nitrogenase component 1 type Oxidoreductase NmrA PF05368.13 EAU88922.1 - 0.13 11.8 0.2 0.38 10.3 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family Big_3_5 PF16640.5 EAU88923.2 - 0.035 14.3 0.0 0.035 14.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) MSA-2c PF12238.8 EAU88923.2 - 0.74 9.8 9.4 1.5 8.8 9.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c TMEM51 PF15345.6 EAU88924.2 - 0.034 14.0 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1180 PF06679.12 EAU88924.2 - 0.52 10.7 0.0 0.52 10.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) FAA_hydrolase PF01557.18 EAU88925.2 - 1.8e-54 184.7 0.0 2.4e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CelD_N PF02927.14 EAU88925.2 - 0.0012 19.6 0.0 0.0028 18.5 0.0 1.7 1 1 0 1 1 1 1 Cellulase N-terminal ig-like domain Neur_chan_memb PF02932.16 EAU88926.2 - 0.01 15.9 0.9 0.014 15.5 0.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2269 PF10027.9 EAU88926.2 - 0.01 15.9 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) GREB1 PF15782.5 EAU88926.2 - 0.026 11.7 2.3 0.03 11.5 2.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Herpes_glycop PF01528.16 EAU88926.2 - 0.027 13.3 0.6 0.039 12.8 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Pox_A14 PF05767.12 EAU88926.2 - 0.063 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4381 PF14316.6 EAU88926.2 - 0.18 12.0 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Macoilin PF09726.9 EAU88926.2 - 0.2 10.2 7.1 0.25 9.8 7.1 1.0 1 0 0 1 1 1 0 Macoilin family Shisa PF13908.6 EAU88926.2 - 0.43 10.8 7.5 2.6 8.2 0.1 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Ctr PF04145.15 EAU88926.2 - 0.67 10.6 4.7 2.5 8.7 4.7 1.8 1 1 0 1 1 1 0 Ctr copper transporter family Miga PF10265.9 EAU88926.2 - 0.69 8.8 2.6 0.88 8.5 2.6 1.2 1 0 0 1 1 1 0 Mitoguardin UPF0239 PF06783.11 EAU88926.2 - 2.3 8.5 7.1 20 5.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0239) DUF4551 PF15087.6 EAU88926.2 - 2.4 6.9 9.0 2.9 6.6 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4834 PF16118.5 EAU88926.2 - 2.8 9.0 8.3 52 4.9 8.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 EAU88926.2 - 3.2 8.7 7.6 40 5.2 7.6 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2615 PF11027.8 EAU88926.2 - 9.2 6.5 5.9 4.8 7.4 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) TPP_enzyme_N PF02776.18 EAU88927.1 - 3e-54 183.2 0.0 6.8e-54 182.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EAU88927.1 - 2e-48 164.1 1.1 2.8e-47 160.3 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAU88927.1 - 1.6e-41 141.3 0.8 2.7e-41 140.5 0.3 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CIDE-N PF02017.15 EAU88927.1 - 0.13 12.3 0.0 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 CIDE-N domain NAD_binding_2 PF03446.15 EAU88927.1 - 0.75 10.0 2.9 16 5.7 0.2 3.0 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase CE2_N PF17996.1 EAU88928.2 - 0.001 19.0 0.0 0.0037 17.2 0.1 1.9 2 1 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Syndecan PF01034.20 EAU88928.2 - 0.062 13.2 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Orf78 PF06024.12 EAU88928.2 - 0.13 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TPP_enzyme_N PF02776.18 EAU88931.2 - 8.9e-54 181.7 0.0 1.7e-53 180.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EAU88931.2 - 1e-45 155.2 0.8 2.1e-44 151.0 0.1 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EAU88931.2 - 1.3e-41 141.5 0.7 2.7e-41 140.5 0.3 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CIDE-N PF02017.15 EAU88931.2 - 0.047 13.7 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 CIDE-N domain DUF3963 PF13124.6 EAU88931.2 - 0.18 11.8 0.2 0.36 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) F-box-like PF12937.7 EAU88933.1 - 6.7e-07 29.1 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EAU88935.2 - 1.1e-23 83.1 23.4 0.0023 18.7 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EAU88935.2 - 4.2e-14 52.2 2.6 8.7e-14 51.1 2.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU88935.2 - 3.2e-11 42.8 3.0 4.6e-11 42.3 1.6 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 EAU88935.2 - 3.4e-06 26.0 3.8 0.53 8.9 0.0 4.6 2 1 1 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EAU88935.2 - 4.6e-06 26.8 0.1 1.5 9.1 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAU88935.2 - 0.00074 18.9 0.2 0.0029 17.0 0.0 2.0 2 1 0 2 2 2 1 WD40-like domain DUF4784 PF16023.5 EAU88935.2 - 0.019 13.9 0.0 5.9 5.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4784) Elongin_A PF06881.11 EAU88935.2 - 0.1 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF5046 PF16465.5 EAU88935.2 - 0.13 11.7 0.3 8 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5046) Cellulase PF00150.18 EAU88936.2 - 4.4e-31 108.4 1.3 8.2e-31 107.5 1.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.23 EAU88937.1 - 1.5e-44 152.1 0.0 3.4e-38 131.3 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU88937.1 - 1.3e-09 38.3 0.1 2.4e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TAF4 PF05236.14 EAU88937.1 - 0.046 13.5 2.0 0.1 12.4 2.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family ResIII PF04851.15 EAU88937.1 - 0.13 12.3 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pam17 PF08566.10 EAU88938.1 - 8.9e-61 204.5 0.0 1.1e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DEAD PF00270.29 EAU88940.1 - 2.8e-45 154.2 0.0 4.5e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU88940.1 - 2.3e-24 85.9 0.0 1.7e-23 83.1 0.0 2.3 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EAU88940.1 - 2.2e-18 66.2 0.3 3.8e-18 65.5 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EAU88940.1 - 0.0032 17.5 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAU88940.1 - 0.18 12.0 0.8 0.65 10.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF836 PF05768.14 EAU88941.2 - 2.7e-11 43.7 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-CCHC PF00098.23 EAU88941.2 - 0.0045 17.0 3.1 0.008 16.2 3.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Thioredoxin_3 PF13192.6 EAU88941.2 - 0.021 14.9 0.2 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain SAPS PF04499.15 EAU88942.2 - 4.9e-124 414.8 0.0 1e-123 413.8 0.0 1.5 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 EAU88942.2 - 0.046 11.6 0.9 0.068 11.1 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adap_comp_sub PF00928.21 EAU88943.2 - 1.8e-78 263.6 0.0 2.2e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAU88943.2 - 0.0043 17.0 0.2 0.016 15.2 0.1 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Adenylsucc_synt PF00709.21 EAU88944.1 - 2.3e-176 586.8 0.0 2.6e-176 586.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase COX16 PF14138.6 EAU88945.2 - 1.2e-30 105.8 0.2 1.6e-30 105.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 RicinB_lectin_2 PF14200.6 EAU88947.1 - 2.9e-64 213.8 35.7 4.8e-15 56.1 0.1 7.7 5 2 4 9 9 9 8 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU88947.1 - 4.1e-22 78.8 4.6 7.2e-09 36.0 0.1 4.9 3 1 2 5 5 5 4 Ricin-type beta-trefoil lectin domain Inhibitor_I66 PF16850.5 EAU88947.1 - 0.026 14.4 6.0 1.8 8.4 0.3 4.6 2 1 3 5 5 5 0 Peptidase inhibitor I66 Fascin PF06268.13 EAU88947.1 - 0.061 13.5 0.0 27 5.1 0.0 3.5 2 2 1 3 3 3 0 Fascin domain RicinB_lectin_2 PF14200.6 EAU88949.1 - 8.6e-59 196.3 30.8 1.7e-13 51.1 0.2 8.2 4 3 4 8 8 8 8 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU88949.1 - 2.7e-18 66.4 16.0 1.7e-06 28.3 1.6 4.9 2 2 5 7 7 7 5 Ricin-type beta-trefoil lectin domain CMS1 PF14617.6 EAU88950.1 - 7.5 5.8 6.0 36 3.6 3.3 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UCMA PF17085.5 EAU88953.1 - 0.00023 21.2 8.0 0.00023 21.2 8.0 2.4 3 0 0 3 3 3 1 Unique cartilage matrix associated protein PipA PF07108.11 EAU88953.1 - 0.00058 19.4 1.0 0.00099 18.7 1.0 1.3 1 0 0 1 1 1 1 PipA protein DUF4594 PF15266.6 EAU88953.1 - 0.00059 20.2 15.0 0.00059 20.2 15.0 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4594) FPN1 PF06963.12 EAU88953.1 - 1.6 7.2 2.7 2.2 6.7 2.7 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Zip PF02535.22 EAU88953.1 - 3.2 6.9 5.8 4.7 6.3 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 EAU88953.1 - 3.6 6.5 18.2 5.8 5.8 18.2 1.3 1 0 0 1 1 1 0 Paf1 MRC1 PF09444.10 EAU88953.1 - 5.7 7.4 24.2 10 6.7 18.2 2.7 2 1 0 2 2 2 0 MRC1-like domain RR_TM4-6 PF06459.12 EAU88953.1 - 9 6.0 10.2 15 5.3 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IML1 PF12257.8 EAU88954.2 - 6.8e-109 363.4 0.0 9.5e-109 362.9 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EAU88954.2 - 2.4e-14 53.1 0.0 6.1e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RicinB_lectin_2 PF14200.6 EAU88955.1 - 4.4e-58 194.0 32.0 1.9e-15 57.4 0.2 8.4 3 2 3 8 8 8 8 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EAU88955.1 - 3.8e-21 75.7 18.9 4.9e-09 36.5 0.8 4.5 2 1 3 5 5 5 4 Ricin-type beta-trefoil lectin domain Inhibitor_I66 PF16850.5 EAU88955.1 - 2.9e-05 24.0 4.3 0.01 15.7 0.3 4.3 3 1 1 4 4 4 1 Peptidase inhibitor I66 PPP1R26_N PF15740.5 EAU88956.2 - 0.32 9.6 1.6 0.4 9.3 1.6 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus zf-C4H2 PF10146.9 EAU88957.1 - 4.6e-07 30.4 0.2 5.4e-07 30.1 0.2 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Fez1 PF06818.15 EAU88957.1 - 0.018 15.5 4.3 0.024 15.1 4.3 1.1 1 0 0 1 1 1 0 Fez1 Vps5 PF09325.10 EAU88957.1 - 0.028 14.0 1.8 0.038 13.5 1.8 1.2 1 0 0 1 1 1 0 Vps5 C terminal like BEX PF04538.12 EAU88957.1 - 0.031 14.9 0.2 0.071 13.7 0.2 1.6 1 0 0 1 1 1 0 Brain expressed X-linked like family DUF2205 PF10224.9 EAU88957.1 - 0.42 10.6 8.0 0.76 9.8 5.2 2.6 1 1 1 2 2 2 0 Short coiled-coil protein AT_hook PF02178.19 EAU88957.1 - 2.1 8.5 8.1 4.6 7.4 8.1 1.6 1 0 0 1 1 1 0 AT hook motif Acetyltransf_1 PF00583.25 EAU88958.2 - 4.5e-08 33.3 0.0 6.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAU88958.2 - 8.1e-07 29.4 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAU88958.2 - 8.8e-07 28.9 0.1 1.4e-06 28.3 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU88958.2 - 9.2e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EAU88958.2 - 0.0034 17.5 0.2 0.0066 16.5 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.7 EAU88960.2 - 1.3e-06 28.2 0.0 3.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU88960.2 - 0.0012 18.7 0.0 0.0047 16.8 0.0 2.1 1 1 0 1 1 1 1 F-box domain Choline_transpo PF04515.12 EAU88963.2 - 4.1e-49 167.5 1.7 4.1e-49 167.5 1.7 2.4 2 1 0 2 2 2 1 Plasma-membrane choline transporter F-box-like PF12937.7 EAU88964.1 - 8e-09 35.3 0.1 2.2e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like DNA_pol_A_exo1 PF01612.20 EAU88964.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease Cyclin_N PF00134.23 EAU88966.2 - 1.3e-11 44.3 0.0 2.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EAU88966.2 - 0.00055 20.3 8.4 0.00083 19.8 4.6 3.1 2 1 0 2 2 2 1 Cyclin PNISR PF15996.5 EAU88966.2 - 0.0024 18.2 3.6 0.0059 16.9 3.6 1.7 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR SWIRM-assoc_2 PF16496.5 EAU88966.2 - 0.0057 15.6 1.4 0.0084 15.0 1.4 1.2 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal Rootletin PF15035.6 EAU88967.2 - 0.035 14.1 0.3 0.082 12.9 0.3 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.18 EAU88967.2 - 0.11 12.8 0.2 0.29 11.5 0.2 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.12 EAU88967.2 - 1.3 9.1 6.6 0.98 9.5 4.4 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_pol_phi PF04931.13 EAU88968.2 - 8.1 4.4 12.4 12 3.8 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi KDZ PF18758.1 EAU88969.1 - 3.4e-46 157.6 0.0 5.5e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU88969.1 - 6.9e-22 77.6 0.2 1.5e-21 76.5 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU88969.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases MFS_5 PF05631.14 EAU88977.2 - 0.026 13.5 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM Lipase_GDSL_2 PF13472.6 EAU88978.2 - 7.6e-11 42.7 0.1 9.4e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Zn_Tnp_IS1595 PF12760.7 EAU88979.2 - 0.00014 21.7 0.3 0.00032 20.6 0.3 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 EAU88979.2 - 0.05 13.3 0.3 0.079 12.7 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EAU88979.2 - 0.14 11.6 0.2 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Nop14 PF04147.12 EAU88980.2 - 2.2 6.4 6.0 3.1 5.9 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family OTCace PF00185.24 EAU88984.1 - 8.2e-48 162.4 0.0 1.1e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EAU88984.1 - 3.9e-44 150.3 0.0 5.4e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain EphA2_TM PF14575.6 EAU88985.1 - 0.16 12.9 0.1 1.4 9.9 0.1 2.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2273 PF10031.9 EAU88985.1 - 0.17 11.9 4.9 0.24 11.4 4.9 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) SKG6 PF08693.10 EAU88985.1 - 6.5 6.2 9.8 16 5.0 9.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3267 PF11667.8 EAU88986.2 - 1.4 9.3 8.4 1.2 9.4 6.0 2.1 1 1 1 2 2 2 0 Putative zincin peptidase Neurensin PF14927.6 EAU88986.2 - 3.1 7.5 5.6 2.8 7.6 0.0 3.3 1 1 2 3 3 3 0 Neurensin Neurensin PF14927.6 EAU88987.1 - 0.2 11.4 4.1 2.5 7.8 0.0 3.4 3 1 1 4 4 4 0 Neurensin Lebercilin PF15619.6 EAU88988.2 - 3.6 7.2 14.9 1.5 8.5 0.1 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.9 EAU88988.2 - 6.6 7.1 9.1 49 4.3 5.9 3.4 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AOX PF01786.17 EAU88999.2 - 1.1e-87 293.1 0.0 1.4e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase RRM PF10378.9 EAU89000.1 - 0.49 10.2 2.9 5.6 6.8 0.0 3.1 3 0 0 3 3 3 0 Putative RRM domain GPHR_N PF12537.8 EAU89002.2 - 0.025 14.6 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal p450 PF00067.22 EAU89003.2 - 7.9e-69 232.6 0.0 1.2e-68 232.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AIG1 PF04548.16 EAU89004.2 - 5.3e-09 35.7 0.0 9.1e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EAU89004.2 - 1.5e-06 28.2 0.0 3.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU89004.2 - 2.2e-05 24.6 0.2 0.24 11.4 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 EAU89004.2 - 0.00039 19.8 0.0 0.00057 19.3 0.0 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 EAU89004.2 - 0.0016 18.4 0.1 0.009 15.9 0.1 2.0 1 1 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 EAU89004.2 - 0.014 14.4 0.0 0.045 12.8 0.0 1.8 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EAU89004.2 - 0.034 14.7 0.0 0.079 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 EAU89004.2 - 0.068 12.9 0.4 4.1 7.1 0.2 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 EAU89005.1 - 5.8e-05 22.6 0.0 9.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAU89005.1 - 0.036 13.4 0.3 0.06 12.7 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EAU89005.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.23 EAU89005.1 - 0.13 12.2 0.3 1 9.3 0.4 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 EAU89006.2 - 2.5e-05 23.8 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAU89006.2 - 0.014 14.7 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EAU89006.2 - 0.15 11.7 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 EAU89007.2 - 6.3e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU89007.2 - 0.071 13.0 0.2 0.28 11.1 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAU89007.2 - 0.1 11.9 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 EAU89008.1 - 6.5e-11 42.0 0.2 1.8e-10 40.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU89008.1 - 0.00061 19.6 0.1 0.002 18.0 0.1 1.9 1 0 0 1 1 1 1 F-box domain Herpes_UL21 PF03252.13 EAU89008.1 - 0.2 10.3 0.0 0.57 8.9 0.0 1.7 3 0 0 3 3 3 0 Herpesvirus UL21 RicinB_lectin_2 PF14200.6 EAU89009.2 - 4.8e-07 30.4 0.0 1.1e-05 26.0 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Crystall_2 PF09076.10 EAU89010.2 - 0.077 12.9 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Tetraspanin PF00335.20 EAU89016.2 - 4.4e-10 39.7 7.8 6.3e-10 39.2 7.8 1.2 1 0 0 1 1 1 1 Tetraspanin family SicP-binding PF09119.10 EAU89016.2 - 0.14 12.1 0.1 4.1 7.5 0.0 2.6 3 0 0 3 3 3 0 SicP binding Tyrosinase PF00264.20 EAU89028.1 - 6.5e-40 137.8 0.0 1.2e-39 136.9 0.0 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF1697 PF08002.11 EAU89028.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) RRM_1 PF00076.22 EAU89029.2 - 2.7e-26 91.2 0.1 1.1e-13 50.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAU89029.2 - 2.7e-12 46.4 0.0 8.8e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU89029.2 - 3.3e-07 30.1 0.0 4.9e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Calcipressin PF04847.12 EAU89029.2 - 0.029 14.1 0.4 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Calcipressin HNH_2 PF13391.6 EAU89030.1 - 1.9e-05 24.7 0.0 3.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease RicinB_lectin_2 PF14200.6 EAU89034.1 - 8.8e-16 58.4 3.8 4.7e-06 27.2 0.0 3.9 1 1 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.6 EAU89036.2 - 1.3e-16 61.1 0.5 3e-07 31.1 0.0 4.3 2 1 4 6 6 6 4 Ricin-type beta-trefoil lectin domain-like Tyrosinase PF00264.20 EAU89037.2 - 9.8e-21 75.1 1.1 3.1e-12 47.3 0.0 2.4 2 1 0 2 2 2 2 Common central domain of tyrosinase RicinB_lectin_2 PF14200.6 EAU89039.1 - 2.1e-14 54.0 0.3 1.2e-07 32.4 0.0 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like HNH_2 PF13391.6 EAU89040.2 - 0.0041 17.2 0.1 0.0087 16.2 0.1 1.7 1 1 0 1 1 1 1 HNH endonuclease F-box-like PF12937.7 EAU89041.1 - 3.5e-10 39.6 1.3 1.4e-09 37.7 1.3 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU89041.1 - 0.43 11.1 7.6 5.1 7.6 1.9 4.2 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) BTB PF00651.31 EAU89045.2 - 3.2e-06 27.3 0.0 1.7e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain CAP_GLY PF01302.25 EAU89045.2 - 7.1e-05 22.7 1.2 0.0049 16.9 0.7 3.3 2 1 0 2 2 2 1 CAP-Gly domain Cas_Csy1 PF09611.10 EAU89046.2 - 0.067 12.2 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Helicase_C PF00271.31 EAU89052.2 - 9.3e-13 48.5 0.0 2.3e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3830 PF12903.7 EAU89072.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) Pkinase PF00069.25 EAU89074.2 - 8.5e-06 25.3 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAU89074.2 - 0.012 14.9 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU89074.2 - 0.026 14.4 0.3 0.28 11.0 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EAU89075.2 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EAU89075.2 - 0.02 14.2 0.2 0.037 13.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU89075.2 - 0.045 13.7 0.1 0.29 11.0 0.2 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EAU89075.2 - 0.22 10.8 0.0 0.45 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase PTCB-BRCT PF12738.7 EAU89078.2 - 2.1e-24 85.3 0.5 2.5e-16 59.4 0.2 4.2 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 EAU89078.2 - 1.2e-22 80.1 0.0 2.2e-12 47.1 0.0 5.4 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EAU89078.2 - 5.9e-22 77.4 0.2 1.5e-16 60.1 0.0 3.7 3 0 0 3 3 3 3 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 EAU89078.2 - 3.2e-20 72.3 0.0 0.00016 22.1 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EAU89078.2 - 0.00014 22.1 0.5 4.7 7.6 0.0 4.4 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain Catalase PF00199.19 EAU89079.1 - 6.2e-155 516.0 0.1 9.6e-155 515.4 0.1 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EAU89079.1 - 9.3e-13 48.2 0.3 1.7e-12 47.4 0.3 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive TPR_2 PF07719.17 EAU89084.2 - 0.0011 18.8 0.5 0.003 17.5 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU89084.2 - 0.052 13.8 0.1 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU89084.2 - 0.071 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU89084.2 - 0.12 13.3 0.3 0.61 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 EAU89090.2 - 5.6e-10 39.3 0.0 1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU89090.2 - 7.5e-07 29.4 0.2 0.046 13.8 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 EAU89090.2 - 2.6e-05 23.6 0.6 0.00022 20.6 0.2 2.4 2 1 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EAU89090.2 - 4.7e-05 23.4 1.1 0.00058 19.8 0.1 2.6 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 EAU89090.2 - 0.00091 19.7 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Septin PF00735.18 EAU89090.2 - 0.0015 17.9 0.0 0.0041 16.4 0.0 1.7 2 0 0 2 2 2 1 Septin IIGP PF05049.13 EAU89090.2 - 0.0034 16.5 0.0 0.023 13.8 0.0 2.1 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EAU89090.2 - 0.063 13.5 0.1 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EAU89090.2 - 0.074 12.6 0.0 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAU89090.2 - 0.089 12.1 0.2 0.88 8.9 0.2 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TMEM154 PF15102.6 EAU89090.2 - 0.1 12.5 0.4 0.2 11.5 0.4 1.5 1 0 0 1 1 1 0 TMEM154 protein family cobW PF02492.19 EAU89090.2 - 0.1 12.2 0.0 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EAU89090.2 - 0.18 11.6 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Tricorn_C1 PF14684.6 EAU89092.1 - 0.019 15.0 0.2 0.04 14.0 0.2 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain Rubella_E1 PF05748.11 EAU89093.2 - 0.0097 14.8 0.1 0.025 13.5 0.0 1.6 2 0 0 2 2 2 1 Rubella membrane glycoprotein E1 CBF PF03914.17 EAU89096.1 - 3.8e-31 108.4 1.3 3.8e-31 108.4 1.3 2.2 3 0 0 3 3 3 1 CBF/Mak21 family GyrI-like PF06445.15 EAU89096.1 - 0.12 12.7 0.1 0.57 10.5 0.0 2.1 2 0 0 2 2 2 0 GyrI-like small molecule binding domain Euplotes_phero PF05842.11 EAU89096.1 - 0.19 12.3 0.0 0.38 11.3 0.0 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Phage_integrase PF00589.22 EAU89100.1 - 2e-05 24.5 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family TMEM237 PF15383.6 EAU89101.2 - 0.093 11.8 1.4 2.6 7.1 0.3 2.6 2 0 0 2 2 2 0 Transmembrane protein 237 WD40 PF00400.32 EAU89102.2 - 1.7e-58 193.2 23.2 1.2e-08 35.5 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EAU89102.2 - 1.1e-26 92.9 5.8 2e-26 92.1 5.8 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EAU89102.2 - 8.8e-19 67.6 0.4 1.2e-05 25.6 0.0 6.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAU89102.2 - 9.7e-09 35.0 0.0 0.061 12.6 0.0 4.7 5 0 0 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 EAU89102.2 - 5.9e-06 25.5 0.1 2.1 7.2 0.0 4.4 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EAU89102.2 - 0.00014 21.8 0.0 0.13 12.1 0.0 3.6 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EAU89102.2 - 0.0049 15.4 0.6 0.034 12.7 0.1 2.4 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 EAU89102.2 - 0.012 14.3 3.7 0.57 8.8 0.0 3.8 2 2 2 5 5 5 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EAU89102.2 - 0.027 13.2 1.6 3.7 6.2 0.0 3.5 2 1 2 4 4 4 0 Nup133 N terminal like Peptidase_S9_N PF02897.15 EAU89102.2 - 0.046 12.5 0.4 2.7 6.7 0.1 3.2 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Phage_lysis PF03245.13 EAU89102.2 - 0.046 13.8 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein BicD PF09730.9 EAU89102.2 - 0.052 12.0 2.1 0.076 11.4 2.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D PD40 PF07676.12 EAU89102.2 - 0.065 13.2 0.3 7.8 6.6 0.0 3.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cluap1 PF10234.9 EAU89102.2 - 0.097 12.1 1.8 0.16 11.3 1.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 ADIP PF11559.8 EAU89102.2 - 0.38 10.8 4.7 0.82 9.7 4.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CEP63 PF17045.5 EAU89102.2 - 0.45 10.4 4.9 0.96 9.3 4.9 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa EzrA PF06160.12 EAU89102.2 - 0.51 8.4 3.2 0.7 8.0 3.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Proteasome_A_N PF10584.9 EAU89102.2 - 1.9 8.2 6.3 87 2.9 0.0 4.6 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Spc7 PF08317.11 EAU89102.2 - 2.9 6.7 5.4 4.2 6.1 5.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 EAU89102.2 - 3.4 8.2 7.4 8.7 6.9 7.4 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region GAS PF13851.6 EAU89103.2 - 5.7e-05 22.6 13.2 5.7e-05 22.6 13.2 6.4 2 1 3 6 6 6 2 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 EAU89103.2 - 0.00011 22.0 21.5 0.00011 22.0 21.5 5.0 3 1 2 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EAU89103.2 - 0.00014 21.8 5.7 0.00014 21.8 5.7 5.3 2 1 3 5 5 5 2 Protein of unknown function (DUF1664) ATG16 PF08614.11 EAU89103.2 - 0.00082 19.7 13.7 0.00082 19.7 13.7 5.9 2 1 3 5 5 5 3 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EAU89103.2 - 0.0019 18.2 12.4 0.0019 18.2 12.4 5.6 1 1 4 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.10 EAU89103.2 - 0.0065 16.9 7.6 0.0065 16.9 7.6 5.4 2 1 3 5 5 4 1 Bacterial type III secretion protein (HrpB7) HIP1_clath_bdg PF16515.5 EAU89103.2 - 0.012 16.3 11.5 0.012 16.3 11.5 7.1 2 2 3 5 5 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DHR10 PF18595.1 EAU89103.2 - 0.02 15.0 3.2 0.02 15.0 3.2 8.2 2 1 5 8 8 8 0 Designed helical repeat protein 10 domain ApoO PF09769.9 EAU89103.2 - 0.57 10.1 0.0 0.57 10.1 0.0 4.3 3 1 1 4 4 3 0 Apolipoprotein O Pox_A_type_inc PF04508.12 EAU89103.2 - 0.67 9.9 14.4 5.6 7.0 0.0 6.0 6 0 0 6 6 5 0 Viral A-type inclusion protein repeat BRE1 PF08647.11 EAU89103.2 - 1.3 9.2 48.4 0.12 12.4 0.8 5.5 3 1 1 6 6 5 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 EAU89103.2 - 2 8.6 31.6 1 9.6 5.2 4.9 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family MscS_porin PF12795.7 EAU89103.2 - 2.2 7.8 78.4 0.52 9.8 35.4 5.4 2 1 4 6 6 5 0 Mechanosensitive ion channel porin domain APG6_N PF17675.1 EAU89103.2 - 2.2 8.8 79.7 0.85 10.2 16.3 6.4 2 1 5 7 7 7 0 Apg6 coiled-coil region YabA PF06156.13 EAU89103.2 - 2.2 8.9 41.1 0.13 12.9 8.5 6.1 3 2 2 5 5 4 0 Initiation control protein YabA Spc7 PF08317.11 EAU89103.2 - 2.7 6.8 65.5 0.097 11.5 20.7 4.7 1 1 4 5 5 5 0 Spc7 kinetochore protein Fez1 PF06818.15 EAU89103.2 - 4.3 7.7 62.3 3.7 8.0 13.0 5.3 2 1 5 7 7 7 0 Fez1 MAD PF05557.13 EAU89103.2 - 5.2 5.3 62.4 1.1e+03 -2.4 43.6 2.8 1 1 0 1 1 1 0 Mitotic checkpoint protein HAP1_N PF04849.13 EAU89103.2 - 6.5 5.9 68.5 0.085 12.0 20.9 4.1 2 1 3 5 5 5 0 HAP1 N-terminal conserved region IFT57 PF10498.9 EAU89103.2 - 7.7 5.4 41.7 0.056 12.4 7.1 4.1 1 1 1 3 3 2 0 Intra-flagellar transport protein 57 TSC22 PF01166.18 EAU89103.2 - 8.8 6.7 21.3 0.87 9.9 0.5 5.9 5 1 1 6 6 5 0 TSC-22/dip/bun family DUF4618 PF15397.6 EAU89103.2 - 9.6 5.5 42.6 0.029 13.8 10.3 4.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) Peptidase_C13 PF01650.18 EAU89109.2 - 2.1e-34 119.2 0.6 2.9e-34 118.8 0.1 1.4 2 0 0 2 2 2 1 Peptidase C13 family HCNGP PF07818.13 EAU89110.1 - 3.4e-19 69.3 0.4 6.4e-19 68.4 0.4 1.4 1 0 0 1 1 1 1 HCNGP-like protein Macoilin PF09726.9 EAU89110.1 - 0.19 10.3 2.7 0.24 9.9 2.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EAU89110.1 - 0.43 9.4 4.3 0.44 9.3 4.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ank_2 PF12796.7 EAU89111.2 - 4.3e-34 117.0 0.0 2.2e-12 47.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU89111.2 - 1.1e-23 80.7 0.5 0.0017 18.6 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAU89111.2 - 5.8e-23 80.7 2.7 4.9e-07 29.9 0.1 6.2 3 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU89111.2 - 7.7e-20 71.0 0.3 9.7e-07 29.2 0.0 5.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU89111.2 - 2.6e-16 59.2 0.1 0.2 12.2 0.0 7.1 6 0 0 6 6 6 4 Ankyrin repeat CCCAP PF15964.5 EAU89111.2 - 0.019 13.3 0.1 0.028 12.7 0.1 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family Pkinase PF00069.25 EAU89112.2 - 3.3e-06 26.6 0.1 5.1e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU89112.2 - 0.0028 17.6 2.1 0.0078 16.2 0.5 2.3 3 1 1 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAU89112.2 - 0.0069 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EAU89112.2 - 0.045 13.1 0.1 0.096 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2 PF00152.20 EAU89113.1 - 4.6e-72 242.7 0.0 7.4e-60 202.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAU89113.1 - 8.2e-09 35.3 0.2 1.4e-08 34.6 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LSM PF01423.22 EAU89114.2 - 7.4e-20 70.4 1.0 1e-19 69.9 1.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAU89114.2 - 0.0087 16.2 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF5549 PF17703.1 EAU89114.2 - 0.028 14.1 1.4 0.034 13.8 1.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) BPL_C PF02237.17 EAU89114.2 - 0.028 14.3 0.3 0.056 13.4 0.3 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Hfq PF17209.3 EAU89114.2 - 0.17 11.5 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Hfq protein Kinesin PF00225.23 EAU89115.1 - 1.3e-93 313.5 0.3 1.3e-93 313.5 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EAU89115.1 - 2e-20 73.3 0.0 4.3e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding TPR_7 PF13176.6 EAU89115.1 - 0.0025 17.7 0.1 0.0062 16.5 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU89115.1 - 0.0036 17.3 0.1 0.0095 16.0 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU89115.1 - 0.0048 17.2 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU89115.1 - 0.0077 16.4 0.0 0.03 14.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU89115.1 - 0.12 13.0 0.0 0.12 13.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU89115.1 - 0.16 12.9 0.1 0.16 12.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat EIF_2_alpha PF07541.12 EAU89116.1 - 1.3e-34 118.8 0.0 2.4e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EAU89116.1 - 2.3e-12 47.1 1.0 4.2e-12 46.2 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain ANAPC15 PF15243.6 EAU89116.1 - 0.39 11.1 2.8 0.52 10.7 0.3 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 15 Gly-rich_Ago1 PF12764.7 EAU89127.2 - 0.027 15.2 5.7 0.25 12.1 0.1 2.2 2 0 0 2 2 2 0 Glycine-rich region of argonaut zf-CCHC PF00098.23 EAU89127.2 - 0.074 13.2 4.4 0.074 13.2 4.4 1.8 2 0 0 2 2 2 0 Zinc knuckle PIF1 PF05970.14 EAU89145.1 - 2.2e-76 257.4 0.0 2.8e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EAU89145.1 - 8.5e-11 41.9 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAU89145.1 - 7.6e-07 28.7 0.0 1.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EAU89145.1 - 9.3e-06 26.1 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EAU89145.1 - 0.00025 21.4 0.0 0.00085 19.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 EAU89145.1 - 0.0033 17.2 0.1 0.064 13.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EAU89145.1 - 0.0094 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Herpes_Helicase PF02689.14 EAU89145.1 - 0.011 13.7 0.0 2.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Helicase AAA_11 PF13086.6 EAU89145.1 - 0.011 15.6 0.0 0.067 13.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA PF00004.29 EAU89145.1 - 0.018 15.5 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAU89145.1 - 0.041 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAU89145.1 - 0.056 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 EAU89145.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 EAU89145.1 - 0.066 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 EAU89145.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain CbiA PF01656.23 EAU89145.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EAU89145.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EAU89145.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EAU89145.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU89145.1 - 0.15 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region CLP1_P PF16575.5 EAU89145.1 - 0.18 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_32 PF13654.6 EAU89145.1 - 0.2 10.4 0.0 0.38 9.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Phage_TAC_1 PF06222.11 EAU89147.1 - 0.015 15.0 2.1 0.028 14.2 2.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone DUF553 PF04473.12 EAU89147.1 - 0.18 11.3 2.1 0.22 11.0 1.8 1.3 1 1 0 1 1 1 0 Transglutaminase-like domain F-box-like PF12937.7 EAU89151.2 - 1.2e-06 28.4 0.0 2.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU89152.1 - 2.1e-09 37.1 0.3 5.9e-09 35.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like NMD3 PF04981.13 EAU89153.1 - 1.2e-79 267.3 0.2 1.6e-79 266.8 0.2 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 EAU89153.1 - 0.035 14.1 5.9 0.5 10.4 5.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon NinF PF05810.12 EAU89153.1 - 0.037 13.9 1.4 0.091 12.6 0.4 2.1 2 0 0 2 2 2 0 NinF protein Rpr2 PF04032.16 EAU89153.1 - 1 9.7 2.9 26 5.2 1.8 2.9 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain WSC PF01822.19 EAU89154.1 - 2.1e-15 56.6 3.0 5.4e-15 55.4 3.0 1.7 1 0 0 1 1 1 1 WSC domain Toxin_3 PF00537.18 EAU89154.1 - 9.8 6.5 10.7 0.63 10.3 4.4 2.2 2 0 0 2 2 2 0 Scorpion toxin-like domain UQ_con PF00179.26 EAU89155.1 - 1.5e-49 167.3 0.0 1.7e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAU89155.1 - 0.00011 21.9 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B F-box-like PF12937.7 EAU89156.2 - 3.1e-11 43.0 0.9 6.7e-11 41.9 0.4 1.9 2 0 0 2 2 2 1 F-box-like HrpB7 PF09486.10 EAU89156.2 - 0.00089 19.7 0.2 0.0014 19.1 0.2 1.2 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) F-box PF00646.33 EAU89156.2 - 0.02 14.8 6.1 0.038 13.9 0.6 3.0 3 0 0 3 3 3 0 F-box domain F-box_5 PF18511.1 EAU89156.2 - 0.025 14.1 0.6 0.062 12.9 0.6 1.6 1 0 0 1 1 1 0 F-box TPR_MLP1_2 PF07926.12 EAU89156.2 - 0.044 13.8 4.0 0.067 13.3 4.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 EAU89156.2 - 0.11 12.2 0.3 0.24 11.2 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Prefoldin_2 PF01920.20 EAU89156.2 - 0.25 11.3 2.6 0.46 10.4 2.6 1.4 1 0 0 1 1 1 0 Prefoldin subunit TMF_DNA_bd PF12329.8 EAU89156.2 - 0.39 10.7 4.8 0.68 10.0 4.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DMPK_coil PF08826.10 EAU89156.2 - 0.42 10.8 4.5 0.86 9.8 4.5 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF4140 PF13600.6 EAU89156.2 - 0.7 10.4 3.7 1.2 9.6 3.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4315 PF14193.6 EAU89156.2 - 0.99 9.5 7.5 7 6.7 0.8 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) NuA4 PF09340.10 EAU89156.2 - 2.2 8.2 3.4 6.5 6.7 1.9 2.1 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 F-box-like PF12937.7 EAU89160.1 - 0.00036 20.4 0.1 0.0014 18.5 0.1 2.1 1 1 0 1 1 1 1 F-box-like CBM_21 PF03370.13 EAU89161.2 - 6.2e-12 45.7 0.4 1.5e-11 44.4 0.4 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EAU89161.2 - 0.00056 20.4 1.4 0.00056 20.4 1.4 2.7 3 0 0 3 3 3 1 Starch/carbohydrate-binding module (family 53) Alpha-amylase PF00128.24 EAU89161.2 - 0.012 15.2 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Glyco_transf_24 PF18404.1 EAU89163.2 - 1.6e-138 460.6 2.8 2.2e-138 460.1 2.8 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EAU89163.2 - 5.4e-61 206.8 0.0 1.1e-56 192.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EAU89163.2 - 2.1e-51 174.5 0.0 4.1e-51 173.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EAU89163.2 - 2.9e-36 123.9 0.0 5.3e-36 123.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 EAU89163.2 - 5.3e-36 123.5 0.0 4.9e-33 113.9 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EAU89163.2 - 1.1e-32 113.7 1.1 1.4e-32 113.4 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EAU89163.2 - 1.1e-06 28.4 0.2 2.3e-06 27.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Doppel PF11466.8 EAU89164.1 - 0.017 14.8 0.6 0.03 14.0 0.6 1.4 1 0 0 1 1 1 0 Prion-like protein Doppel CsbD PF05532.12 EAU89165.1 - 2.9e-19 68.7 13.4 3e-11 43.0 2.0 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.12 EAU89165.1 - 0.027 14.8 0.6 0.045 14.1 0.2 1.7 2 1 0 2 2 2 0 Heat shock protein 9/12 CsbD PF05532.12 EAU89166.1 - 7.6e-17 61.0 12.8 7.9e-10 38.5 2.4 2.3 1 1 1 2 2 2 2 CsbD-like DEAD PF00270.29 EAU89171.1 - 3e-41 141.1 0.1 5.3e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU89171.1 - 1.2e-27 96.4 0.6 9.5e-27 93.5 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EAU89171.1 - 0.011 15.1 0.2 0.031 13.6 0.2 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit eIF-3_zeta PF05091.12 EAU89171.1 - 1.6 7.6 9.6 2.4 7.0 9.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SPX PF03105.19 EAU89172.2 - 2.5 7.9 6.0 3.2 7.6 6.0 1.1 1 0 0 1 1 1 0 SPX domain MAGE_N PF12440.8 EAU89172.2 - 3.1 8.5 13.7 0.22 12.2 5.8 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal COesterase PF00135.28 EAU89173.2 - 3.3e-63 214.3 0.0 1.4e-41 143.0 0.0 3.3 2 2 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU89173.2 - 8.4e-05 22.5 0.0 0.00019 21.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1769 PF08588.10 EAU89174.1 - 9.2e-24 83.4 0.2 2.1e-23 82.3 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) SPX PF03105.19 EAU89174.1 - 5.2 6.9 9.8 6.9 6.5 9.8 1.1 1 0 0 1 1 1 0 SPX domain Glyco_hydro_61 PF03443.14 EAU89176.2 - 7e-33 114.3 0.0 9.2e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4537 PF15057.6 EAU89176.2 - 0.19 11.8 0.0 0.77 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) DUF4470 PF14737.6 EAU89177.2 - 1.6e-25 89.1 0.0 3.2e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) HMMR_N PF15905.5 EAU89178.1 - 0.0058 16.2 6.1 0.0058 16.2 6.1 2.9 1 1 1 3 3 3 1 Hyaluronan mediated motility receptor N-terminal YebG PF07130.12 EAU89178.1 - 0.041 13.7 5.6 0.11 12.3 0.5 3.2 3 0 0 3 3 3 0 YebG protein TLE_N PF03920.15 EAU89178.1 - 0.058 13.5 0.9 0.058 13.5 0.9 2.4 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Leucyl-specific PF14795.6 EAU89178.1 - 0.18 11.9 2.8 1.1 9.4 0.5 2.9 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF948 PF06103.11 EAU89178.1 - 1.8 8.9 6.7 7.1 7.0 1.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EAU89178.1 - 2.6 8.6 7.0 1.6 9.2 1.5 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein G-alpha PF00503.20 EAU89179.2 - 1.2e-114 383.2 0.0 1.4e-114 383.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU89179.2 - 5.1e-11 42.3 0.0 3.3e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EAU89179.2 - 0.019 15.2 0.0 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EAU89179.2 - 0.031 14.7 0.2 0.1 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EAU89179.2 - 0.038 13.7 0.0 0.097 12.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EAU89179.2 - 0.11 12.1 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EAU89179.2 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EAU89179.2 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain BRE1 PF08647.11 EAU89179.2 - 1.1 9.4 4.1 0.43 10.7 1.1 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3658 PF12395.8 EAU89179.2 - 1.5 8.7 4.2 1.1 9.2 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function Cu-oxidase PF00394.22 EAU89180.2 - 4.1e-40 137.5 0.0 2.9e-39 134.8 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU89180.2 - 2e-28 98.8 4.4 7.6e-26 90.5 0.1 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU89180.2 - 7.1e-26 90.6 3.5 1.9e-22 79.5 0.4 3.7 3 1 0 3 3 3 2 Multicopper oxidase DUF4470 PF14737.6 EAU89182.2 - 1.5e-22 79.6 0.1 2.5e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) WD40 PF00400.32 EAU89183.1 - 7.7e-55 181.6 20.6 1.7e-07 31.8 1.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EAU89183.1 - 1.4e-26 92.6 5.9 2.6e-26 91.7 5.9 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EAU89183.1 - 3.6e-12 46.4 0.0 0.0011 19.2 0.0 6.2 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU89183.1 - 9.4e-06 24.8 0.3 2 7.3 0.0 5.1 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EAU89183.1 - 0.00025 20.5 0.0 0.2 10.9 0.0 4.1 4 0 0 4 4 4 1 WD40-like domain Golgin_A5 PF09787.9 EAU89183.1 - 0.0066 15.9 0.5 0.0066 15.9 0.5 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 5 PD40 PF07676.12 EAU89183.1 - 0.025 14.5 0.0 47 4.1 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EAU89183.1 - 0.055 12.0 0.3 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain Cu-oxidase PF00394.22 EAU89184.2 - 1.1e-39 136.1 0.0 9.6e-39 133.0 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU89184.2 - 1.1e-20 73.7 1.6 9.3e-19 67.5 0.2 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU89184.2 - 9.4e-12 45.0 0.9 2.9e-09 37.0 0.3 2.8 2 0 0 2 2 2 2 Multicopper oxidase adh_short_C2 PF13561.6 EAU89185.2 - 1.2e-43 149.4 0.3 5e-41 140.8 0.3 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU89185.2 - 1.7e-32 112.5 3.7 1.2e-23 83.6 1.1 2.9 2 1 1 3 3 3 3 short chain dehydrogenase KR PF08659.10 EAU89185.2 - 0.01 15.7 2.2 0.022 14.7 0.2 2.3 1 1 1 2 2 2 0 KR domain UPF0113 PF03657.13 EAU89186.1 - 0.28 11.5 2.4 82 3.6 0.0 4.2 5 0 0 5 5 5 0 UPF0113 PUA domain AIG1 PF04548.16 EAU89187.2 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 EAU89187.2 - 0.21 11.7 0.1 0.66 10.0 0.0 1.8 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.23 EAU89188.2 - 2.6e-10 40.4 0.1 4.4e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU89188.2 - 2.4e-09 37.5 1.5 4e-06 27.0 0.4 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EAU89188.2 - 6.4e-07 28.9 0.0 7.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EAU89188.2 - 3.5e-05 23.8 0.1 6.5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 EAU89188.2 - 8.2e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_29 PF13555.6 EAU89188.2 - 0.00031 20.4 0.2 0.00067 19.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EAU89188.2 - 0.00049 20.6 0.0 0.0008 19.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter T2SSE PF00437.20 EAU89188.2 - 0.00052 19.2 0.0 0.00078 18.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EAU89188.2 - 0.0015 18.3 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EAU89188.2 - 0.0021 18.0 0.1 0.0074 16.2 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EAU89188.2 - 0.0025 18.2 0.5 0.0078 16.6 0.2 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU89188.2 - 0.0051 17.1 0.1 0.029 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EAU89188.2 - 0.009 15.6 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EAU89188.2 - 0.01 16.4 0.5 0.073 13.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAU89188.2 - 0.016 14.4 0.1 0.03 13.5 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain DLIC PF05783.11 EAU89188.2 - 0.016 14.1 0.0 0.032 13.1 0.0 1.4 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Viral_helicase1 PF01443.18 EAU89188.2 - 0.017 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EAU89188.2 - 0.021 14.8 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.18 EAU89188.2 - 0.035 13.6 0.2 0.052 13.1 0.2 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 EAU89188.2 - 0.04 14.5 0.2 0.066 13.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAU89188.2 - 0.041 13.8 0.1 0.073 13.0 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 EAU89188.2 - 0.053 13.7 0.0 0.16 12.2 0.1 1.7 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 EAU89188.2 - 0.064 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 EAU89188.2 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EAU89188.2 - 0.073 13.5 0.1 0.21 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA PF00004.29 EAU89188.2 - 0.092 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EAU89188.2 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 EAU89188.2 - 0.11 12.8 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 EAU89188.2 - 0.13 11.0 0.2 0.25 10.1 0.2 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF2075 PF09848.9 EAU89188.2 - 0.14 11.4 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EAU89188.2 - 0.18 12.0 0.3 2.5 8.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 EAU89188.2 - 0.2 11.0 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EAU89188.2 - 0.2 11.2 0.1 0.33 10.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribo_biogen_C PF04034.13 EAU89189.2 - 2e-50 169.8 0.0 2.7e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EAU89189.2 - 5.6e-14 51.7 0.2 8.8e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Pns11_12 PF17464.2 EAU89189.2 - 1.4 8.6 6.6 0.38 10.4 2.9 1.8 2 0 0 2 2 2 0 Non-structural protein 11 and 12 MRP-L27 PF09809.9 EAU89190.1 - 1.3e-09 37.8 0.2 2e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Ricin_B_lectin PF00652.22 EAU89191.1 - 1.2e-23 83.8 5.4 2.1e-23 82.9 5.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EAU89191.1 - 6.2e-16 58.9 11.3 5.3e-09 36.7 0.3 2.9 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 EAU89191.1 - 0.28 10.8 4.9 5.9 6.5 0.2 3.0 2 1 0 3 3 3 0 Cytolethal distending toxin A/C domain MMR_HSR1 PF01926.23 EAU89192.1 - 4.6e-08 33.1 0.0 6.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU89192.1 - 1.2e-06 28.7 0.5 0.042 13.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 EAU89192.1 - 1.6e-06 27.7 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 EAU89192.1 - 5.2e-06 25.9 0.0 6.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EAU89192.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase FPV060 PF17614.2 EAU89192.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Viral CC-type chemokine IIGP PF05049.13 EAU89192.1 - 0.069 12.2 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 EAU89193.2 - 1.7e-07 31.3 0.0 3.8e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU89193.2 - 7.1e-05 22.9 0.6 0.26 11.3 0.2 2.2 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 EAU89193.2 - 0.00042 19.7 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 EAU89193.2 - 0.0013 19.3 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.16 EAU89193.2 - 0.0023 17.3 0.2 0.0066 15.8 0.1 1.8 2 1 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EAU89193.2 - 0.0033 17.3 3.0 0.0093 15.9 0.7 2.5 2 1 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EAU89193.2 - 0.0042 16.2 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 EAU89193.2 - 0.0055 16.4 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF87 PF01935.17 EAU89193.2 - 0.0082 16.3 0.2 0.015 15.4 0.2 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 EAU89193.2 - 0.013 15.2 0.2 0.05 13.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EAU89193.2 - 0.022 15.3 0.5 0.038 14.5 0.5 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EAU89193.2 - 0.025 14.0 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 EAU89193.2 - 0.028 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 EAU89193.2 - 0.032 13.7 0.0 0.19 11.2 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EAU89193.2 - 0.095 13.2 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EAU89193.2 - 0.095 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EAU89193.2 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 EAU89193.2 - 0.16 12.3 0.1 0.3 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EAU89197.2 - 0.00041 20.4 0.3 0.0028 17.7 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU89197.2 - 0.065 13.3 0.2 0.23 11.5 0.1 1.8 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 EAU89197.2 - 0.067 13.1 0.8 2.9 7.8 0.1 2.4 1 1 1 2 2 2 0 RsgA GTPase LptE PF04390.12 EAU89197.2 - 0.1 13.3 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly PAS_9 PF13426.7 EAU89202.1 - 1.1e-26 93.1 0.0 1.8e-16 60.3 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EAU89202.1 - 2.2e-16 59.9 0.0 2.6e-06 27.6 0.0 5.4 5 1 0 5 5 5 3 PAS fold PAS PF00989.25 EAU89202.1 - 7.1e-15 55.0 0.0 8.7e-07 28.9 0.0 4.2 3 2 0 3 3 3 2 PAS fold PAS_4 PF08448.10 EAU89202.1 - 3.4e-08 33.7 0.0 6.1e-05 23.2 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 EAU89202.1 - 7.1e-06 26.1 1.4 0.00045 20.3 0.0 3.2 2 1 0 2 2 2 1 PAS domain PAS_8 PF13188.7 EAU89202.1 - 3.7e-05 23.6 0.0 0.01 15.8 0.0 2.6 2 0 0 2 2 2 1 PAS domain bZIP_C PF12498.8 EAU89202.1 - 1 10.4 0.0 1 10.4 0.0 3.0 3 0 0 3 3 3 0 Basic leucine-zipper C terminal Ribosomal_L16 PF00252.18 EAU89203.1 - 1.8e-46 157.4 0.0 2.3e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e EthD PF07110.11 EAU89204.1 - 0.045 14.9 0.0 0.056 14.6 0.0 1.3 1 0 0 1 1 1 0 EthD domain PfkB PF00294.24 EAU89206.2 - 6.5e-30 104.5 0.0 8.4e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Torus PF16131.5 EAU89207.1 - 1.2e-08 35.7 6.6 0.00073 20.2 0.4 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 EAU89207.1 - 4.1e-07 29.6 12.5 0.00025 20.8 2.5 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAU89207.1 - 4.1e-05 23.5 13.8 0.00033 20.6 2.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 EAU89207.1 - 4.6e-05 23.6 0.9 8.1e-05 22.8 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 EAU89207.1 - 0.00043 20.1 10.3 0.0016 18.3 2.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.23 EAU89208.1 - 4.6e-23 81.5 0.0 7.4e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.16 EAU89208.1 - 3.5e-17 62.4 0.0 9.7e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EAU89208.1 - 9.7e-17 61.4 0.5 3.7e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EAU89208.1 - 5.5e-12 46.1 8.1 0.025 14.6 0.3 4.3 2 2 2 4 4 4 4 Dynamin family Septin PF00735.18 EAU89208.1 - 3.9e-11 42.7 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 Septin IIGP PF05049.13 EAU89208.1 - 4.7e-09 35.8 0.6 0.00085 18.5 0.0 2.3 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EAU89208.1 - 4.9e-09 36.6 0.0 0.004 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EAU89208.1 - 6.7e-09 36.4 0.0 0.00046 20.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EAU89208.1 - 4.5e-07 30.4 0.1 0.026 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Roc PF08477.13 EAU89208.1 - 1.8e-05 25.0 0.1 0.082 13.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EAU89208.1 - 4e-05 23.2 1.0 0.36 10.3 0.1 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region FeoB_N PF02421.18 EAU89208.1 - 9.1e-05 22.0 0.1 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_29 PF13555.6 EAU89208.1 - 9.5e-05 22.1 2.7 0.3 10.9 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EAU89208.1 - 0.00018 21.3 0.1 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EAU89208.1 - 0.00032 20.6 0.3 0.69 9.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 EAU89208.1 - 0.00048 20.5 0.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase GBP PF02263.19 EAU89208.1 - 0.00051 19.4 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain FtsK_SpoIIIE PF01580.18 EAU89208.1 - 0.00089 18.7 0.2 0.073 12.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.26 EAU89208.1 - 0.001 18.8 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Ras PF00071.22 EAU89208.1 - 0.0014 18.2 0.2 0.27 10.8 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_33 PF13671.6 EAU89208.1 - 0.0041 17.3 0.1 2.1 8.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EAU89208.1 - 0.0053 15.9 0.5 0.6 9.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein SRPRB PF09439.10 EAU89208.1 - 0.011 15.2 0.1 0.78 9.1 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA PF00004.29 EAU89208.1 - 0.012 16.0 0.0 5.7 7.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAU89208.1 - 0.013 15.5 0.6 1.4 8.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAU89208.1 - 0.016 15.8 0.0 6 7.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EAU89208.1 - 0.024 13.8 0.1 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 EAU89208.1 - 0.028 13.6 0.1 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EAU89208.1 - 0.034 13.4 0.2 5 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EAU89208.1 - 0.035 14.0 0.8 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 EAU89208.1 - 0.038 13.9 0.2 2 8.3 0.1 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 EAU89208.1 - 0.04 13.7 0.1 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 EAU89208.1 - 0.044 13.9 4.8 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain GTP_EFTU PF00009.27 EAU89208.1 - 0.058 12.9 1.7 21 4.6 0.1 3.6 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 EAU89208.1 - 0.059 13.4 0.6 7.6 6.5 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EAU89208.1 - 0.065 13.7 7.9 2.2 8.7 0.1 2.6 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 EAU89208.1 - 0.072 12.9 0.6 6.6 6.4 0.1 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 EAU89208.1 - 0.11 12.1 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EAU89208.1 - 0.12 12.1 0.2 7.9 6.2 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein SRP54 PF00448.22 EAU89208.1 - 0.18 11.4 0.1 50 3.4 0.1 3.1 2 1 0 3 3 3 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EAU89210.1 - 7.1e-09 35.8 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU89210.1 - 3.8e-05 23.7 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EAU89210.1 - 4.6e-05 22.8 0.0 9.6e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 EAU89210.1 - 0.00023 21.6 0.0 0.00059 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EAU89210.1 - 0.0017 18.0 0.1 0.016 14.8 0.3 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EAU89210.1 - 0.0032 17.2 0.1 0.015 15.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EAU89210.1 - 0.0038 17.8 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Septin PF00735.18 EAU89210.1 - 0.004 16.5 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EAU89210.1 - 0.0045 17.1 0.3 0.12 12.4 0.5 2.5 1 1 0 2 2 2 1 Dynamin family DUF815 PF05673.13 EAU89210.1 - 0.013 14.6 0.0 0.095 11.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 EAU89210.1 - 0.03 14.6 0.0 0.092 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EAU89210.1 - 0.062 13.2 0.0 0.4 10.5 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EAU89210.1 - 0.28 11.7 0.5 0.71 10.3 0.2 1.7 2 0 0 2 2 2 0 AAA domain Glyco_hydro_79C PF16862.5 EAU89212.2 - 8e-18 65.2 0.0 1.6e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Vps55 PF04133.14 EAU89214.1 - 0.17 11.8 6.2 1.2 9.1 1.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 55 DUF373 PF04123.13 EAU89214.1 - 0.23 10.9 2.6 5.2 6.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) KDZ PF18758.1 EAU89215.2 - 1.5e-45 155.5 0.0 3e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 EAU89215.2 - 2.8e-12 47.0 0.0 5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 EAU89215.2 - 2.2e-06 27.8 0.0 5.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU89215.2 - 0.00035 20.7 0.1 0.00081 19.5 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Herpes_U5 PF05999.11 EAU89215.2 - 0.11 11.2 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family DASH_Spc19 PF08287.11 EAU89215.2 - 1.5 8.7 11.5 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Spc19 DUF4407 PF14362.6 EAU89215.2 - 7.5 5.8 13.7 3.1 7.0 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PP1_bind PF15276.6 EAU89216.1 - 0.34 11.2 0.0 0.34 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein phosphatase 1 binding DUF1572 PF07609.11 EAU89217.1 - 0.13 12.0 0.6 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) APO_RNA-bind PF05634.11 EAU89218.2 - 0.0059 16.0 0.3 0.0086 15.5 0.3 1.2 1 0 0 1 1 1 1 APO RNA-binding KBP_C PF12309.8 EAU89218.2 - 0.034 13.7 3.1 0.046 13.3 3.1 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DUF922 PF06037.11 EAU89219.1 - 0.042 13.6 0.3 0.068 13.0 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Cauli_VI PF01693.16 EAU89221.1 - 1.5e-06 28.3 0.6 2.4e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin HET PF06985.11 EAU89223.2 - 5.3e-06 26.8 0.6 0.0022 18.4 0.0 2.7 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Wzz PF02706.15 EAU89224.1 - 0.74 10.2 4.8 8.6 6.7 1.3 2.6 2 0 0 2 2 2 0 Chain length determinant protein CsbD PF05532.12 EAU89228.1 - 0.00027 20.8 3.0 0.00062 19.6 3.0 1.6 1 0 0 1 1 1 1 CsbD-like Mid2 PF04478.12 EAU89229.1 - 0.046 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3455 PF11937.8 EAU89230.1 - 1.7e-23 83.7 0.0 2.2e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Oxidored_FMN PF00724.20 EAU89231.1 - 2.8e-62 211.0 0.0 3.8e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EAU89231.1 - 0.0019 17.4 0.0 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DnaJ PF00226.31 EAU89235.1 - 2.7e-21 75.4 0.3 3.1e-20 72.1 0.3 2.8 3 0 0 3 3 3 1 DnaJ domain Peptidase_S49 PF01343.18 EAU89235.1 - 0.017 15.1 0.3 0.029 14.3 0.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 Borrelia_P83 PF05262.11 EAU89235.1 - 0.13 10.7 13.6 0.17 10.3 13.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF5401 PF17380.2 EAU89235.1 - 4.2 5.3 23.1 0.017 13.2 11.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Exonuc_VII_L PF02601.15 EAU89235.1 - 6.4 6.3 9.1 8.9 5.8 9.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1754 PF08555.10 EAU89237.1 - 0.0093 16.7 1.2 0.0093 16.7 1.2 1.7 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Imm7 PF15585.6 EAU89237.1 - 0.089 13.1 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 7 DUF3391 PF11871.8 EAU89237.1 - 6.6 7.3 7.7 12 6.4 7.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) TA0956 PF11513.8 EAU89239.2 - 0.015 15.5 0.0 0.035 14.3 0.0 1.6 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 Nup96 PF12110.8 EAU89241.1 - 2e-85 286.4 1.5 3.1e-85 285.8 0.0 1.8 2 0 0 2 2 2 1 Nuclear protein 96 Nop14 PF04147.12 EAU89241.1 - 0.094 10.9 12.4 0.13 10.4 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAU89241.1 - 0.38 9.0 10.3 0.52 8.6 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF773 PF05600.12 EAU89241.1 - 1.1 7.9 4.1 1.6 7.4 4.1 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 BUD22 PF09073.10 EAU89241.1 - 1.2 8.4 15.7 1.8 7.8 15.7 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 EAU89241.1 - 1.3 7.5 17.8 2 6.9 17.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.14 EAU89241.1 - 3.2 7.5 12.9 7.8 6.2 12.9 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 EAU89241.1 - 6.9 6.3 11.1 22 4.7 11.1 1.9 1 0 0 1 1 1 0 FAM176 family Glyco_hydro_53 PF07745.13 EAU89242.1 - 3.4e-89 299.2 0.1 3.8e-89 299.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 EAU89242.1 - 1.7e-05 24.4 1.3 3e-05 23.6 1.4 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LRR_6 PF13516.6 EAU89243.1 - 9.2e-06 25.3 15.7 0.76 10.0 0.2 5.5 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 EAU89243.1 - 0.0045 17.4 9.1 0.85 10.1 0.2 4.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) EMP24_GP25L PF01105.24 EAU89245.1 - 7.4e-37 127.0 0.0 8.5e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ycf4 PF02392.16 EAU89245.1 - 0.072 12.6 0.3 0.24 10.9 0.1 1.9 2 1 0 2 2 2 0 Ycf4 MBA1 PF07961.11 EAU89246.2 - 1.1e-10 41.0 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 EAU89246.2 - 0.0088 16.2 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 1 Tim44-like domain DUF2076 PF09849.9 EAU89247.2 - 0.0068 16.5 0.2 0.0073 16.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EAU89247.2 - 0.038 14.1 4.5 0.1 12.8 3.8 1.8 1 1 1 2 2 2 0 CHCH domain FtsK_alpha PF17854.1 EAU89249.1 - 0.11 12.7 0.6 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 FtsK alpha domain Histone_HNS PF00816.21 EAU89249.1 - 0.22 12.4 0.2 0.22 12.4 0.2 2.8 3 0 0 3 3 3 0 H-NS histone family DDE_Tnp_ISL3 PF01610.17 EAU89249.1 - 0.22 11.2 4.0 0.13 12.0 1.6 1.7 2 0 0 2 2 2 0 Transposase TMF_DNA_bd PF12329.8 EAU89249.1 - 1.7 8.7 10.4 0.12 12.4 2.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Arabinose_Iso_C PF11762.8 EAU89250.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain C2 PF00168.30 EAU89251.1 - 2.7e-69 230.0 1.3 8.1e-20 71.0 0.2 4.9 4 0 0 4 4 4 4 C2 domain E1-E2_ATPase PF00122.20 EAU89252.1 - 4.2e-49 166.5 0.0 4.2e-49 166.5 0.0 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EAU89252.1 - 1.2e-18 68.2 2.4 1.7e-18 67.7 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAU89252.1 - 1.3e-14 53.7 0.1 2.6e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAU89252.1 - 1e-05 25.4 0.1 0.00053 19.8 0.0 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAU89252.1 - 0.036 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Tad PF13400.6 EAU89252.1 - 0.49 10.7 5.5 13 6.2 0.7 3.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Fungal_trans PF04082.18 EAU89253.2 - 1.4e-34 119.4 0.0 2.3e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EAU89255.1 - 6.5e-29 101.0 28.7 3.3e-18 65.8 9.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EAU89256.1 - 2.2e-26 92.6 38.5 2.3e-17 62.9 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.24 EAU89257.2 - 1.9e-17 63.9 0.0 2.3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAU89257.2 - 6.7e-16 57.7 1.1 1.3e-15 56.9 1.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAU89257.2 - 1.3e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU89258.1 - 8.1e-23 81.2 2.9 1.2e-22 80.7 2.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAU89258.1 - 6.2e-06 26.4 0.1 6.2e-06 26.4 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EAU89258.1 - 0.00027 21.4 0.0 0.00052 20.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 EAU89258.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 EAU89258.1 - 0.03 14.4 0.3 0.035 14.1 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein DUF1018 PF06252.12 EAU89258.1 - 0.055 14.5 0.6 0.096 13.7 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.11 EAU89258.1 - 0.074 12.7 0.1 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein PWI PF01480.17 EAU89259.2 - 2.2e-27 95.2 0.1 3.5e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 PWI domain Glyco_hydro_61 PF03443.14 EAU89260.1 - 9.4e-59 198.8 0.3 1.4e-58 198.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAU89260.1 - 1.9e-11 43.7 17.8 1.9e-11 43.7 17.8 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.14 EAU89261.1 - 1.6e-56 191.5 0.2 2.4e-56 190.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EAU89261.1 - 1.4e-11 44.1 17.5 1.4e-11 44.1 17.5 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain fn3_3 PF14686.6 EAU89261.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II Bestrophin PF01062.21 EAU89262.2 - 1.9e-34 119.4 0.9 1.9e-22 80.0 0.2 2.5 2 1 1 3 3 3 2 Bestrophin, RFP-TM, chloride channel PHD20L1_u1 PF16660.5 EAU89262.2 - 0.07 13.9 2.2 0.14 12.9 2.2 1.5 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 XK-related PF09815.9 EAU89262.2 - 0.77 8.7 7.6 0.9 8.5 1.3 2.1 2 0 0 2 2 2 0 XK-related protein WBP-1 PF11669.8 EAU89263.2 - 0.17 12.5 0.8 0.57 10.8 0.0 2.2 3 0 0 3 3 3 0 WW domain-binding protein 1 Glyco_hydro_61 PF03443.14 EAU89264.2 - 2.6e-54 184.3 0.7 3.4e-54 183.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cupredoxin_1 PF13473.6 EAU89264.2 - 0.19 11.9 0.0 0.73 10.0 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Glyco_transf_90 PF05686.12 EAU89266.2 - 5.6e-09 35.4 0.1 1.3e-06 27.6 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 TPR_7 PF13176.6 EAU89267.1 - 1e-10 40.9 0.0 0.031 14.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat MIT PF04212.18 EAU89267.1 - 5e-09 36.1 0.0 0.15 12.1 0.0 3.7 3 0 0 3 3 3 3 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EAU89267.1 - 7.1e-06 25.8 0.0 2.1 8.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAU89267.1 - 6.9e-05 23.1 0.2 12 6.3 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAU89267.1 - 0.0039 17.9 0.6 12 7.0 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU89267.1 - 0.0098 15.7 0.1 4.1 7.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU89267.1 - 0.011 15.9 0.0 5.8 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU89267.1 - 0.064 12.9 0.2 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 TPR repeat HMG_box PF00505.19 EAU89271.2 - 1.1e-10 41.7 0.3 2.2e-10 40.8 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU89271.2 - 0.011 16.3 0.1 0.019 15.5 0.1 1.4 1 0 0 1 1 1 0 HMG-box domain Glycophorin_A PF01102.18 EAU89271.2 - 0.013 15.7 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Syndecan PF01034.20 EAU89271.2 - 0.028 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain COX14 PF14880.6 EAU89272.2 - 0.094 12.6 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Sec62 PF03839.16 EAU89274.1 - 3.7e-59 199.9 0.0 4.8e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF2161 PF09929.9 EAU89274.1 - 0.19 11.9 0.8 3 8.0 0.0 2.8 3 0 0 3 3 3 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) DUF3413 PF11893.8 EAU89274.1 - 5.6 6.1 9.8 8.2 5.5 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) HAD_2 PF13419.6 EAU89275.1 - 2.6e-05 24.4 0.0 0.0095 16.0 0.0 3.2 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU89275.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tubulin-binding PF00418.19 EAU89277.2 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Yeast-kill-tox PF09207.11 EAU89278.1 - 4 8.1 10.9 4.5 8.0 1.6 2.3 1 1 1 2 2 2 0 Yeast killer toxin MFS_1 PF07690.16 EAU89279.2 - 3.3e-39 134.8 44.1 3.3e-39 134.8 44.1 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU89279.2 - 3.5e-06 26.2 0.8 3.5e-06 26.2 0.8 3.7 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 EAU89279.2 - 0.0015 17.0 6.8 0.0028 16.1 6.8 1.4 1 1 0 1 1 1 1 Transmembrane secretion effector FPN1 PF06963.12 EAU89279.2 - 0.033 12.8 0.9 3.1 6.2 0.0 2.7 3 0 0 3 3 3 0 Ferroportin1 (FPN1) EXS PF03124.14 EAU89280.2 - 4.1e-73 246.6 29.0 2e-72 244.3 29.0 1.9 1 1 0 1 1 1 1 EXS family SPX PF03105.19 EAU89280.2 - 2.5e-61 208.7 2.5 3.2e-61 208.4 2.5 1.1 1 0 0 1 1 1 1 SPX domain Glyco_transf_22 PF03901.17 EAU89281.2 - 2.9e-59 201.4 16.4 3.7e-59 201.0 16.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Vps16_N PF04841.13 EAU89282.2 - 2.8e-86 289.9 0.0 3.6e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EAU89282.2 - 2.9e-75 253.3 0.0 6.8e-75 252.1 0.0 1.5 1 1 0 1 1 1 1 Vps16, C-terminal region RmlD_sub_bind PF04321.17 EAU89284.2 - 7e-58 196.0 0.0 8.5e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EAU89284.2 - 1.8e-22 80.0 0.0 2.2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAU89284.2 - 2.2e-08 33.9 0.0 4.7e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EAU89284.2 - 8.7e-07 28.4 0.0 5.6e-05 22.4 0.0 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 EAU89284.2 - 0.02 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EAU89284.2 - 0.11 11.6 0.0 1.4 8.0 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein LSM PF01423.22 EAU89286.1 - 1.9e-16 59.5 0.1 2.4e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain TPT PF03151.16 EAU89287.2 - 5.1e-23 81.9 19.9 6.6e-23 81.5 19.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAU89287.2 - 0.096 12.9 32.9 0.054 13.7 10.3 2.5 2 1 0 2 2 2 0 EamA-like transporter family TMEM238 PF15125.6 EAU89287.2 - 1 9.6 7.4 1.9 8.8 5.6 2.3 1 1 0 1 1 1 0 TMEM238 protein family DUF155 PF02582.14 EAU89288.2 - 2.7e-47 161.1 0.0 4.9e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Arm-DNA-bind_3 PF13356.6 EAU89290.1 - 0.085 13.2 0.1 0.28 11.6 0.1 1.9 2 0 0 2 2 2 0 Arm DNA-binding domain F-box-like PF12937.7 EAU89291.1 - 0.027 14.4 0.1 0.061 13.2 0.1 1.6 1 0 0 1 1 1 0 F-box-like Zn_ribbon_SprT PF17283.2 EAU89291.1 - 0.075 13.0 8.2 0.51 10.3 0.2 3.5 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF4194 PF13835.6 EAU89291.1 - 0.086 12.6 0.8 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) F-box PF00646.33 EAU89291.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain Sec20 PF03908.13 EAU89292.1 - 5.6e-18 64.7 8.0 2.3e-17 62.7 3.6 2.7 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 EAU89292.1 - 0.00097 18.6 0.8 0.00097 18.6 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) DUF1640 PF07798.11 EAU89292.1 - 0.0062 16.6 0.1 0.014 15.5 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) YtxH PF12732.7 EAU89292.1 - 0.059 13.9 0.3 0.059 13.9 0.3 2.3 3 0 0 3 3 3 0 YtxH-like protein HisKA_3 PF07730.13 EAU89292.1 - 9.4 6.8 9.5 2.6 8.7 0.9 2.9 2 1 0 2 2 2 0 Histidine kinase Cnd3 PF12719.7 EAU89293.2 - 2.5e-69 233.7 6.7 1e-68 231.7 5.2 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EAU89293.2 - 1.3e-07 31.9 6.4 6.1e-06 26.5 0.2 3.9 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EAU89293.2 - 3.4e-06 26.9 1.1 0.7 10.3 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EAU89293.2 - 0.0011 19.0 0.1 0.073 13.1 0.0 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.6 EAU89293.2 - 0.0091 15.9 0.3 0.031 14.1 0.3 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal HEAT_EZ PF13513.6 EAU89293.2 - 0.022 15.3 0.3 0.022 15.3 0.3 3.0 3 0 0 3 3 3 0 HEAT-like repeat CLASP_N PF12348.8 EAU89293.2 - 0.06 12.9 0.0 17 4.9 0.0 2.7 2 1 0 2 2 2 0 CLASP N terminal RTP1_C1 PF10363.9 EAU89293.2 - 0.089 13.0 0.0 0.45 10.7 0.0 2.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Sod_Fe_C PF02777.18 EAU89294.1 - 2.3e-35 120.8 0.6 3.8e-35 120.1 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EAU89294.1 - 4.9e-32 110.2 3.1 1e-31 109.2 2.1 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain RNase_PH PF01138.21 EAU89296.2 - 3.1e-31 108.6 0.0 5.1e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EAU89296.2 - 0.00018 21.5 0.1 0.00033 20.6 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 p450 PF00067.22 EAU89297.2 - 7.3e-70 236.0 0.0 8.3e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_lectin PF07938.12 EAU89297.2 - 0.12 11.7 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Fungal fucose-specific lectin TRI5 PF06330.11 EAU89298.1 - 4.8e-18 65.1 0.3 6.6e-18 64.7 0.3 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.22 EAU89299.1 - 1e-70 238.8 0.0 1.3e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MscS_porin PF12795.7 EAU89299.1 - 0.042 13.4 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Transket_pyr PF02779.24 EAU89300.2 - 1.4e-60 204.0 0.0 2e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EAU89300.2 - 1.6e-46 157.8 0.0 2.6e-46 157.1 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EAU89300.2 - 2.8e-30 105.3 0.0 5.4e-30 104.4 0.0 1.4 1 1 0 1 1 1 1 Dehydrogenase E1 component F-box PF00646.33 EAU89301.2 - 9.7e-05 22.1 0.0 0.00028 20.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU89301.2 - 0.00038 20.3 0.1 0.00085 19.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Ferric_reduct PF01794.19 EAU89303.2 - 2.4e-17 63.2 16.1 6.6e-17 61.8 16.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAU89303.2 - 3.6e-07 30.4 0.6 0.0051 16.9 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAU89303.2 - 0.00036 20.6 0.0 0.0015 18.6 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EAU89303.2 - 0.043 14.5 0.0 0.1 13.2 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain RVP PF00077.20 EAU89305.2 - 0.1 12.9 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Mad3_BUB1_I PF08311.12 EAU89306.1 - 1.5e-34 118.6 0.0 2.5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Sec23_trunk PF04811.15 EAU89307.2 - 2.7e-73 246.5 0.0 5.2e-73 245.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EAU89307.2 - 1.5e-22 79.3 0.1 4.2e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EAU89307.2 - 6.3e-16 58.1 7.8 1.4e-15 57.0 7.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EAU89307.2 - 1e-13 51.8 0.1 2.7e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EAU89307.2 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 EAU89307.2 - 1.3e-05 25.2 2.6 1.3e-05 25.2 2.6 2.3 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 EAU89307.2 - 0.025 14.0 0.9 0.053 12.9 0.9 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ATP-synt_10 PF05176.14 EAU89309.1 - 1.1e-64 218.2 0.0 1.4e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein CHASE4 PF05228.13 EAU89309.1 - 0.13 12.5 0.1 21 5.3 0.1 2.2 2 0 0 2 2 2 0 CHASE4 domain Histone PF00125.24 EAU89310.1 - 8.2e-18 65.0 0.0 1.1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAU89310.1 - 4.2e-16 58.4 0.1 8.3e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAU89310.1 - 1.2e-06 28.6 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF563 PF04577.14 EAU89311.2 - 3.8e-05 23.9 0.0 0.00014 22.1 0.0 1.7 1 1 0 2 2 2 1 Protein of unknown function (DUF563) MFS_1 PF07690.16 EAU89312.1 - 1.8e-39 135.6 50.8 2.7e-39 135.1 50.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EAU89312.1 - 0.0021 16.5 8.3 0.0033 15.9 8.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.24 EAU89312.1 - 0.21 10.4 36.2 1.2 7.9 36.3 2.5 1 1 0 1 1 1 0 Sugar (and other) transporter DJ-1_PfpI PF01965.24 EAU89313.1 - 1.4e-10 41.2 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family RRM_1 PF00076.22 EAU89315.2 - 1.5e-34 117.6 0.0 9.6e-13 47.8 0.0 4.5 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EAU89315.2 - 3.9e-08 33.4 2.1 0.0011 19.1 0.1 3.4 3 0 0 3 3 3 2 Poly-adenylate binding protein, unique domain PAM2 PF07145.15 EAU89315.2 - 0.012 15.3 2.3 0.035 13.8 2.3 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region RRM_1 PF00076.22 EAU89316.2 - 1.9e-12 46.8 0.0 2.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EAU89316.2 - 3.6e-08 33.8 0.2 3.6e-08 33.8 0.2 2.3 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Btz PF09405.10 EAU89316.2 - 0.064 13.5 2.3 0.081 13.2 0.1 2.0 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding RRM_8 PF11835.8 EAU89316.2 - 0.071 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain LEA_6 PF10714.9 EAU89316.2 - 1 9.4 8.2 0.43 10.7 0.5 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 WD40 PF00400.32 EAU89317.2 - 7e-30 102.6 26.9 0.00096 19.9 0.7 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU89317.2 - 2.8e-16 59.6 0.0 0.016 15.5 0.0 6.5 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EAU89317.2 - 0.0058 16.5 3.7 0.75 9.8 0.6 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EAU89317.2 - 0.0086 15.1 0.0 0.68 8.8 0.0 3.2 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EAU89317.2 - 0.043 12.4 0.7 4.5 5.7 0.1 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain DUF5122 PF17164.4 EAU89317.2 - 0.091 13.1 2.0 1.2 9.5 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Pheromone PF08015.11 EAU89320.1 - 2.9e-10 41.1 1.4 5.2e-10 40.2 1.4 1.4 1 1 0 1 1 1 1 Fungal mating-type pheromone SPC25 PF06703.11 EAU89321.2 - 1.4e-48 164.7 0.0 3e-48 163.7 0.0 1.5 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Terpene_synth_C PF03936.16 EAU89322.2 - 2.4e-05 23.8 0.0 4.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 EAU89322.2 - 0.076 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal MFS_1 PF07690.16 EAU89323.2 - 3.3e-21 75.6 27.2 1e-17 64.1 7.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EAU89323.2 - 0.34 9.7 16.6 2.8 6.7 0.5 3.0 2 1 0 2 2 2 0 MFS_1 like family ACTH_domain PF00976.18 EAU89325.2 - 0.43 10.6 1.1 0.92 9.5 1.1 1.6 1 0 0 1 1 1 0 Corticotropin ACTH domain LRR_4 PF12799.7 EAU89325.2 - 0.75 10.3 20.9 0.37 11.3 2.7 5.6 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) DEAD PF00270.29 EAU89326.2 - 1.1e-41 142.5 0.1 2.7e-41 141.3 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU89326.2 - 1.8e-28 99.1 0.0 1.1e-26 93.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU89326.2 - 8.2e-05 22.7 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DrsE_2 PF13686.6 EAU89329.2 - 0.019 14.9 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family RAMP4 PF06624.12 EAU89329.2 - 0.054 13.6 2.9 4.7 7.4 0.1 2.3 2 1 0 2 2 2 0 Ribosome associated membrane protein RAMP4 WD40 PF00400.32 EAU89331.2 - 1.9e-44 148.7 22.1 9.9e-09 35.7 0.1 12.3 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU89331.2 - 1.5e-28 98.9 0.0 0.00037 20.7 0.0 9.8 6 2 6 12 12 12 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EAU89331.2 - 2.3e-22 79.3 0.1 3.9e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EAU89331.2 - 2.8e-10 39.7 5.1 0.12 11.4 0.0 7.4 3 2 3 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 EAU89331.2 - 4.2e-06 26.7 0.0 0.0011 18.8 0.0 3.2 2 2 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 EAU89331.2 - 0.00011 21.6 0.0 0.33 10.3 0.0 3.6 3 1 0 4 4 4 2 WD40-like domain PQQ_2 PF13360.6 EAU89331.2 - 0.00065 19.3 1.8 0.35 10.4 0.2 3.6 3 1 1 4 4 4 1 PQQ-like domain PD40 PF07676.12 EAU89331.2 - 0.0075 16.2 10.8 3.7 7.6 0.0 6.5 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EAU89331.2 - 0.01 15.2 0.2 18 4.5 0.0 4.6 4 1 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal RAB3GAP2_N PF14655.6 EAU89331.2 - 0.013 14.8 0.1 0.39 9.9 0.0 3.3 4 1 1 5 5 5 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RPN1_RPN2_N PF17781.1 EAU89331.2 - 0.15 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain PQQ PF01011.21 EAU89331.2 - 0.96 9.5 4.4 26 5.0 0.0 4.0 5 0 0 5 5 4 0 PQQ enzyme repeat PQQ_3 PF13570.6 EAU89331.2 - 3.2 8.4 11.1 6.4 7.4 0.0 5.5 6 1 1 7 7 7 0 PQQ-like domain DUF4748 PF15932.5 EAU89334.2 - 0.037 13.8 0.2 0.056 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) TPR_14 PF13428.6 EAU89336.1 - 3.5e-25 86.5 38.6 0.0006 20.4 0.1 12.9 5 2 10 15 15 14 9 Tetratricopeptide repeat HAT PF02184.16 EAU89336.1 - 2.2e-24 85.1 53.0 8.8e-09 35.2 3.0 13.3 14 1 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EAU89336.1 - 2.7e-18 66.2 4.5 0.016 15.7 0.0 7.4 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EAU89336.1 - 1.6e-13 49.6 14.0 0.059 13.5 0.0 9.1 11 0 0 11 11 8 3 Tetratricopeptide repeat Suf PF05843.14 EAU89336.1 - 5.8e-11 42.9 27.1 0.00027 21.0 0.5 7.1 3 3 0 5 5 5 3 Suppressor of forked protein (Suf) TPR_16 PF13432.6 EAU89336.1 - 1.1e-10 42.0 14.3 0.16 12.6 0.3 7.7 6 3 2 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAU89336.1 - 9e-10 38.3 3.1 2.2e-05 24.5 0.2 6.6 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU89336.1 - 9.4e-09 34.8 1.8 3.3 8.2 0.0 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU89336.1 - 1.5e-07 30.9 0.1 5.9 6.9 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EAU89336.1 - 6.5e-07 28.8 24.6 0.27 10.4 1.2 5.9 2 2 1 4 4 4 4 Tetratricopeptide repeat SNAP PF14938.6 EAU89336.1 - 1.5e-05 24.5 4.1 0.0038 16.7 1.4 3.9 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 EAU89336.1 - 0.0001 22.1 9.1 32 4.9 0.0 7.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU89336.1 - 0.00011 21.8 2.0 6.3 6.6 0.0 5.4 6 0 0 6 6 6 1 TPR repeat Mad3_BUB1_I PF08311.12 EAU89336.1 - 0.00017 21.6 21.3 0.78 9.7 0.9 7.9 5 3 3 9 9 9 3 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 EAU89336.1 - 0.00032 21.1 13.8 4.5 8.1 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAU89336.1 - 0.00051 20.1 15.0 0.47 10.6 0.6 5.7 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU89336.1 - 0.00066 19.9 15.8 0.0059 16.9 0.0 6.5 6 1 1 7 7 6 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EAU89336.1 - 0.017 15.2 14.8 0.038 14.1 0.5 5.3 4 2 1 5 5 5 0 U3 small nucleolar RNA-associated protein 6 TPR_3 PF07720.12 EAU89336.1 - 0.043 13.8 2.3 41 4.3 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EAU89336.1 - 0.92 9.8 6.4 0.72 10.1 0.5 3.5 4 0 0 4 4 3 0 c-SKI Smad4 binding domain TPR_4 PF07721.14 EAU89336.1 - 2 9.3 8.1 1.3e+02 3.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Cnd3 PF12719.7 EAU89337.2 - 7.6e-44 150.1 8.3 3e-39 135.0 0.9 3.4 3 1 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EAU89337.2 - 0.0009 19.3 4.8 4.6 7.8 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EAU89337.2 - 0.0026 18.1 6.4 0.058 13.8 1.0 4.3 4 1 0 4 4 4 1 HEAT repeats Fanconi_A_N PF15865.5 EAU89337.2 - 0.31 10.4 3.4 18 4.6 0.2 3.3 3 0 0 3 3 3 0 Fanconi anaemia group A protein N terminus HEAT_EZ PF13513.6 EAU89337.2 - 1.4 9.5 4.9 15 6.2 0.1 4.0 3 1 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.7 EAU89337.2 - 2.6 8.1 9.7 4.9 7.2 0.2 4.7 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EAU89338.2 - 5.3e-36 124.3 9.2 3.7e-29 101.8 0.5 4.5 3 1 1 4 4 4 4 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EAU89338.2 - 8.2e-06 26.1 1.5 0.00011 22.5 0.2 3.4 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.22 EAU89338.2 - 0.0085 16.3 1.0 6.3 7.4 0.3 5.1 5 0 0 5 5 5 1 HEAT repeat IFRD PF05004.13 EAU89338.2 - 0.013 14.6 0.7 0.044 12.9 0.0 2.2 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) STAT1_TAZ2bind PF12162.8 EAU89338.2 - 0.022 14.3 1.6 0.26 10.9 0.7 2.5 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Cnd1 PF12717.7 EAU89338.2 - 0.13 12.3 5.2 0.6 10.1 0.2 4.2 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 FliT PF05400.13 EAU89339.1 - 0.16 12.8 1.3 0.82 10.5 0.6 2.1 2 1 0 2 2 2 0 Flagellar protein FliT F-box-like PF12937.7 EAU89340.1 - 5e-08 32.7 0.1 2.3e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU89340.1 - 0.34 10.8 6.8 0.33 10.9 0.2 3.5 3 0 0 3 3 3 0 F-box domain Pkinase PF00069.25 EAU89342.2 - 1.2e-44 152.7 0.0 1.7e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89342.2 - 7.3e-24 84.4 0.0 1e-23 84.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU89342.2 - 0.003 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EAU89342.2 - 0.0057 15.7 0.2 0.01 14.8 0.2 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EAU89342.2 - 0.015 15.2 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CAML PF14963.6 EAU89343.1 - 0.18 11.9 6.0 0.29 11.2 6.0 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand SLC12 PF03522.15 EAU89343.1 - 2.1 7.3 6.0 2.8 6.8 6.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2981 PF11200.8 EAU89343.1 - 4.5 6.9 6.1 6 6.5 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Ndc1_Nup PF09531.10 EAU89343.1 - 5.3 5.6 9.1 5.7 5.5 9.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AP3D1 PF06375.11 EAU89344.2 - 0.11 12.7 4.6 1.4 9.1 2.2 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 BRF1 PF07741.13 EAU89344.2 - 8.9 6.7 10.8 18 5.7 6.0 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Ribosomal_S5_C PF03719.15 EAU89345.2 - 8.4e-18 63.6 0.0 2.1e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EAU89345.2 - 1.4e-11 44.2 0.5 3e-11 43.1 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PHB_depo_C PF06850.11 EAU89345.2 - 0.028 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus PITH PF06201.13 EAU89346.2 - 7.8e-39 133.3 0.0 9.5e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 PITH domain C2 PF00168.30 EAU89347.2 - 1.7e-16 60.4 0.0 3.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain COesterase PF00135.28 EAU89349.2 - 8.4e-48 163.5 0.0 4.5e-26 91.8 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family COesterase PF00135.28 EAU89350.1 - 1.3e-91 308.1 0.0 1.5e-91 307.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU89350.1 - 8.1e-11 42.2 0.0 2.1e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU89350.1 - 0.0065 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_transf_90 PF05686.12 EAU89351.1 - 5.9e-20 71.5 0.1 1.2e-19 70.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 COesterase PF00135.28 EAU89353.1 - 2.2e-91 307.3 0.0 2.7e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU89353.1 - 1.5e-08 34.8 0.2 4.8e-08 33.1 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU89353.1 - 0.038 13.5 0.1 0.059 12.8 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family CAP59_mtransfer PF11735.8 EAU89357.1 - 4.3e-80 268.9 0.0 5.2e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3313 PF11769.8 EAU89357.1 - 0.0083 16.0 0.0 0.028 14.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3313) p450 PF00067.22 EAU89364.2 - 8.5e-36 123.7 0.0 1.5e-35 122.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Neugrin PF06413.11 EAU89365.1 - 1.5e-12 48.0 1.7 2.2e-12 47.5 1.7 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EAU89365.1 - 1.3e-07 31.9 6.6 1.9e-07 31.4 6.6 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 EAU89365.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 HTH domain Sigma70_r4 PF04545.16 EAU89365.1 - 0.019 14.5 0.1 0.19 11.3 0.1 2.6 1 1 0 1 1 1 0 Sigma-70, region 4 Rrf2 PF02082.20 EAU89365.1 - 0.036 14.4 0.0 0.063 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator HTH_32 PF13565.6 EAU89365.1 - 0.078 13.6 0.6 0.078 13.6 0.6 2.6 2 1 0 2 2 2 0 Homeodomain-like domain UPF0240 PF06784.11 EAU89365.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0240) Cofilin_ADF PF00241.20 EAU89366.2 - 3.5e-25 88.2 0.1 3.9e-25 88.0 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.25 EAU89367.1 - 1.9e-16 60.3 0.0 2.3e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAU89367.1 - 1.2e-06 28.8 0.0 2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EAU89367.1 - 0.00014 22.5 0.0 0.0002 22.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAU89367.1 - 0.00031 20.7 0.0 0.00039 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU89367.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EAU89367.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NAC PF01849.18 EAU89368.1 - 1.1e-23 83.0 0.1 1.8e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 NAC domain PIG-S PF10510.9 EAU89369.2 - 5.8e-93 312.5 9.7 1.2e-57 195.9 0.1 3.1 1 1 2 3 3 3 3 Phosphatidylinositol-glycan biosynthesis class S protein Myb_DNA-binding PF00249.31 EAU89370.2 - 1.3e-06 28.5 0.0 4.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU89370.2 - 8.6e-05 22.7 0.0 0.00025 21.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Glyco_hydro_47 PF01532.20 EAU89371.2 - 3.2e-122 408.7 0.0 3.7e-122 408.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Transferase PF02458.15 EAU89372.2 - 0.13 10.9 0.0 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Transferase family F-box-like PF12937.7 EAU89373.1 - 5.6e-07 29.3 0.2 2.1e-06 27.5 0.2 2.0 1 0 0 1 1 1 1 F-box-like LRR_5 PF13306.6 EAU89373.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Peptidase_M48_N PF16491.5 EAU89374.1 - 0.081 12.8 0.0 0.097 12.6 0.0 1.0 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices VirB8 PF04335.13 EAU89375.2 - 0.098 12.5 0.6 0.67 9.7 0.1 1.9 2 0 0 2 2 2 0 VirB8 protein Glyco_hydro_16 PF00722.21 EAU89376.2 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 DUF5437 PF17505.2 EAU89376.2 - 0.37 10.8 1.3 1.3 9.1 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5437) UQ_con PF00179.26 EAU89378.2 - 1.8e-53 180.0 0.0 2e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAU89378.2 - 0.0055 17.0 0.0 0.0067 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EAU89378.2 - 0.015 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EAU89378.2 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain Suppressor_APC PF11414.8 EAU89379.2 - 0.12 12.5 1.9 0.35 11.0 0.1 2.5 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein PIG-L PF02585.17 EAU89380.2 - 5.1e-20 72.4 0.1 1.6e-18 67.6 0.1 2.2 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.10 EAU89382.1 - 0.0002 22.3 1.0 0.00043 21.2 0.1 1.9 1 1 1 2 2 2 1 Fungal protein of unknown function (DUF1770) CENP-Q PF13094.6 EAU89382.1 - 0.19 11.9 0.1 0.33 11.1 0.0 1.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit p450 PF00067.22 EAU89384.1 - 3.3e-76 256.9 0.0 1.6e-75 254.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 EAU89385.2 - 1.1e-22 80.0 0.0 2.7e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU89385.2 - 5.5e-14 51.9 0.0 1.2e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU89385.2 - 8.1e-09 35.6 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EAU89385.2 - 6.4e-05 23.3 0.0 0.0011 19.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAU89385.2 - 8e-05 22.8 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 EAU89386.1 - 1.2e-07 31.5 1.4 3.8e-07 29.9 1.4 1.9 1 0 0 1 1 1 1 F-box-like OPT PF03169.15 EAU89388.1 - 1.3e-92 311.5 33.2 1.5e-92 311.2 33.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ubiquitin PF00240.23 EAU89389.1 - 7.2e-13 48.1 0.0 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 EAU89389.1 - 2.2e-05 24.8 0.1 3.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD PF11976.8 EAU89389.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Get5_bdg PF16843.5 EAU89389.1 - 0.095 12.2 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein Ndufs5 PF10200.9 EAU89390.1 - 3e-05 24.2 0.4 3.8e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 EAU89390.1 - 0.006 16.6 1.0 0.0092 16.0 1.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EAU89390.1 - 0.088 13.0 1.5 0.19 11.9 1.5 1.6 1 1 0 1 1 1 0 CHCH domain Het-C PF07217.11 EAU89390.1 - 0.096 11.2 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3128 PF11326.8 EAU89390.1 - 0.23 11.8 4.2 0.65 10.4 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) HMG_box PF00505.19 EAU89391.2 - 1.2e-10 41.7 5.6 2.7e-10 40.5 5.6 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU89391.2 - 0.002 18.7 0.9 0.0048 17.5 0.9 1.6 1 0 0 1 1 1 1 HMG-box domain Nucleo_P87 PF07267.11 EAU89391.2 - 2.1 7.1 6.8 2.8 6.7 6.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box PF00646.33 EAU89393.2 - 0.017 15.0 2.2 0.021 14.7 0.2 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EAU89393.2 - 0.064 13.2 0.1 0.28 11.1 0.1 2.2 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 EAU89394.1 - 8.7e-64 215.4 0.0 1e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89394.1 - 1.9e-27 96.2 0.0 2.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU89394.1 - 5.1e-06 26.0 0.0 7.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAU89394.1 - 0.00023 20.6 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAU89394.1 - 0.00062 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EAU89394.1 - 0.0031 17.5 0.3 1.4 8.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAU89394.1 - 0.036 13.0 0.2 0.07 12.1 0.2 1.4 1 1 0 1 1 1 0 Haspin like kinase domain NTF2 PF02136.20 EAU89395.1 - 1.5e-28 99.7 0.2 2.2e-28 99.2 0.2 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EAU89395.1 - 2.3e-10 40.2 0.0 3.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAU89395.1 - 0.00055 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 EAU89395.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4518 PF15008.6 EAU89395.1 - 0.25 10.5 0.1 0.38 9.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Het-C PF07217.11 EAU89396.1 - 1.5e-214 713.7 0.0 2e-214 713.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PsbH PF00737.20 EAU89397.2 - 0.25 11.1 1.7 0.6 9.9 0.5 2.2 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Glyco_hydro_61 PF03443.14 EAU89398.2 - 4.9e-52 176.9 0.0 5.5e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 EAU89399.2 - 2.8e-47 161.3 0.0 4e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89399.2 - 1.6e-28 99.7 0.0 2.3e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU89399.2 - 5.3e-08 32.5 0.0 7.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAU89399.2 - 0.0045 16.4 0.3 0.0083 15.5 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU89399.2 - 0.0072 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAU89399.2 - 0.041 12.9 0.2 0.041 12.9 0.2 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Gln-synt_C PF00120.24 EAU89400.1 - 8.9e-67 225.5 0.0 1.3e-66 224.9 0.0 1.3 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EAU89400.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain Gln-synt_C PF00120.24 EAU89401.2 - 4.1e-64 216.7 0.0 6.3e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EAU89401.2 - 0.092 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutamine synthetase N-terminal domain DASH_Dam1 PF08653.10 EAU89402.1 - 6.5e-19 67.5 1.3 1.4e-18 66.4 1.3 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 Velvet PF11754.8 EAU89402.1 - 0.025 14.5 0.5 0.028 14.4 0.5 1.1 1 0 0 1 1 1 0 Velvet factor CCDC84 PF14968.6 EAU89402.1 - 0.067 12.8 1.3 0.092 12.4 1.3 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 NAPRTase_N PF17767.1 EAU89402.1 - 0.082 13.3 1.7 0.11 12.8 0.2 2.0 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Band_7 PF01145.25 EAU89402.1 - 0.19 11.7 3.3 0.3 11.1 3.3 1.4 1 0 0 1 1 1 0 SPFH domain / Band 7 family Dicty_REP PF05086.12 EAU89402.1 - 0.23 9.4 1.7 0.29 9.1 1.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.9 EAU89402.1 - 0.59 8.6 7.9 0.7 8.4 7.9 1.2 1 0 0 1 1 1 0 Macoilin family CBM_1 PF00734.18 EAU89405.1 - 1.8e-07 31.0 0.2 1.8e-07 31.0 0.2 3.5 4 1 0 4 4 4 1 Fungal cellulose binding domain BTB PF00651.31 EAU89406.1 - 0.00065 19.9 0.1 0.036 14.3 0.0 2.9 2 1 1 3 3 3 1 BTB/POZ domain DUF2684 PF10885.8 EAU89406.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) NDUF_B7 PF05676.13 EAU89407.1 - 2.2e-31 107.4 3.5 2.6e-31 107.1 3.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Glyco_hydro_61 PF03443.14 EAU89408.2 - 1.3e-54 185.3 0.0 1.5e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MAPEG PF01124.18 EAU89409.2 - 2.9e-14 53.1 0.9 3.3e-14 52.9 0.9 1.1 1 0 0 1 1 1 1 MAPEG family Glyoxal_oxid_N PF07250.11 EAU89410.1 - 9.5e-29 100.3 0.3 6.6e-14 51.7 0.0 4.6 5 0 0 5 5 5 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EAU89410.1 - 3.5e-20 72.1 0.2 7.4e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 EAU89410.1 - 0.00017 21.5 2.9 0.056 13.4 0.1 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Histone PF00125.24 EAU89413.1 - 3.8e-23 82.3 1.0 5.2e-23 81.8 1.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EAU89413.1 - 2.6e-06 27.6 0.1 6.3e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EAU89413.1 - 0.00028 21.3 0.0 0.00053 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 EAU89413.1 - 0.019 15.2 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein Bt_P21 PF05560.11 EAU89413.1 - 0.077 12.6 0.1 0.095 12.3 0.1 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone PF00125.24 EAU89414.1 - 2.5e-18 66.7 0.0 3.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EAU89414.1 - 1.7e-16 59.7 0.4 3.5e-16 58.6 0.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EAU89414.1 - 1.7e-06 28.2 0.0 2.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MFS_1 PF07690.16 EAU89415.2 - 1.2e-13 50.7 46.2 7.7e-12 44.8 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PH_9 PF15410.6 EAU89416.2 - 4.8e-06 26.9 0.0 0.01 16.2 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 EAU89416.2 - 0.00067 20.1 0.0 0.34 11.4 0.0 2.6 2 0 0 2 2 2 2 PH domain Metallophos PF00149.28 EAU89417.1 - 3.3e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAU89417.1 - 1e-21 77.1 0.5 2.1e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Sugar_tr PF00083.24 EAU89418.1 - 3.6e-88 296.4 24.8 4.1e-88 296.2 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU89418.1 - 5.8e-26 91.3 28.0 1.3e-21 77.0 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.9 EAU89419.2 - 3.4e-32 111.2 2.0 6.7e-32 110.3 0.1 2.5 2 0 0 2 2 2 1 Autophagy-related protein 11 DUF2316 PF10078.9 EAU89419.2 - 4 7.8 8.0 1.1 9.6 0.5 3.6 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) F-box-like PF12937.7 EAU89421.2 - 0.044 13.7 0.2 0.089 12.7 0.2 1.6 1 0 0 1 1 1 0 F-box-like Polysacc_lyase PF14099.6 EAU89422.2 - 5.5e-06 26.4 0.0 3.7e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide lyase Mcp5_PH PF12814.7 EAU89423.1 - 4e-46 156.1 0.4 9.4e-46 154.9 0.1 1.8 2 0 0 2 2 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EAU89423.1 - 1.5e-05 25.4 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 PH domain ERM PF00769.19 EAU89423.1 - 0.00038 20.4 15.7 0.00038 20.4 15.7 3.4 3 0 0 3 3 3 1 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 EAU89423.1 - 0.00044 19.8 15.8 0.00044 19.8 15.8 2.8 3 0 0 3 3 3 1 Golgin subfamily A member 5 Filament PF00038.21 EAU89423.1 - 0.00095 18.8 18.2 0.00095 18.8 18.2 2.4 3 0 0 3 3 3 1 Intermediate filament protein DUF812 PF05667.11 EAU89423.1 - 0.0011 18.0 15.2 0.0011 17.9 11.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Fez1 PF06818.15 EAU89423.1 - 0.0042 17.6 17.1 0.0042 17.6 17.1 2.5 2 0 0 2 2 2 1 Fez1 IMCp PF12314.8 EAU89423.1 - 0.0052 17.0 108.2 0.21 11.9 29.4 3.7 2 1 1 3 3 3 2 Inner membrane complex protein KASH_CCD PF14662.6 EAU89423.1 - 0.0053 16.6 19.2 0.0053 16.6 19.2 2.5 3 0 0 3 3 2 1 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 EAU89423.1 - 0.0099 16.1 1.4 0.0099 16.1 1.4 4.3 3 1 1 4 4 4 1 Autophagy protein 16 (ATG16) RCC1 PF00415.18 EAU89423.1 - 0.036 14.7 0.3 0.16 12.6 0.3 2.3 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Spc7 PF08317.11 EAU89423.1 - 0.13 11.1 24.4 0.045 12.6 19.0 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EAU89423.1 - 0.87 9.6 26.5 0.54 10.3 19.7 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 EAU89423.1 - 1.1 9.1 25.9 1.9 8.3 4.4 3.4 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF4763 PF15960.5 EAU89423.1 - 1.2 8.4 18.3 2.7 7.2 13.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) V_ATPase_I PF01496.19 EAU89423.1 - 2.7 5.8 10.5 5.1 4.9 10.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.8 EAU89423.1 - 2.9 8.0 41.3 0.36 10.9 13.5 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding GCN5L1 PF06320.13 EAU89423.1 - 6.2 7.0 15.7 0.18 11.9 7.5 2.8 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) CENP-Q PF13094.6 EAU89423.1 - 9 6.5 32.5 9.4 6.4 0.2 4.7 3 1 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Sec23_trunk PF04811.15 EAU89424.2 - 2.6e-48 164.7 0.0 3.8e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAU89424.2 - 3.4e-18 66.2 0.2 9.3e-18 64.8 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EAU89424.2 - 5.7e-15 55.1 3.6 1.4e-14 53.9 3.6 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EAU89424.2 - 1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Sec23_helical PF04815.15 EAU89424.2 - 5.7e-06 26.1 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain F-box-like PF12937.7 EAU89425.2 - 0.0025 17.7 0.0 0.0063 16.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like PDEase_I PF00233.19 EAU89427.2 - 5.3e-51 173.6 0.0 1.1e-50 172.5 0.0 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EAU89427.2 - 0.11 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 HD domain MutS_V PF00488.21 EAU89431.2 - 2.1e-64 217.0 0.1 4.2e-64 216.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAU89431.2 - 3.2e-39 135.1 0.2 3.2e-39 135.1 0.2 2.3 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EAU89431.2 - 2.4e-34 118.0 0.2 8.9e-34 116.1 0.1 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EAU89431.2 - 1.9e-10 41.1 0.1 9.9e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 MutS domain II 3HCDH_N PF02737.18 EAU89431.2 - 0.019 14.8 1.7 1.9 8.4 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_27 PF13514.6 EAU89431.2 - 0.036 13.6 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAU89431.2 - 0.06 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_IV PF05190.18 EAU89431.2 - 0.083 13.2 0.1 0.25 11.7 0.1 1.9 1 0 0 1 1 1 0 MutS family domain IV YAcAr PF10686.9 EAU89431.2 - 0.09 12.7 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family AAA_23 PF13476.6 EAU89431.2 - 0.19 12.2 0.0 0.19 12.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF4139 PF13598.6 EAU89433.2 - 1.2e-38 132.9 0.0 4.5e-38 131.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EAU89433.2 - 2.2e-22 79.3 4.2 3.4e-20 72.3 0.1 2.5 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) DUF5082 PF16888.5 EAU89433.2 - 0.004 17.4 0.4 0.0068 16.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) APG6_N PF17675.1 EAU89433.2 - 0.016 15.7 3.3 0.026 15.1 3.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 EAU89433.2 - 0.017 15.5 2.2 0.03 14.7 2.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FapA PF03961.13 EAU89433.2 - 0.039 12.6 0.2 0.057 12.0 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CortBP2 PF09727.9 EAU89433.2 - 0.064 13.2 1.1 0.13 12.2 1.1 1.5 1 0 0 1 1 1 0 Cortactin-binding protein-2 DASH_Spc19 PF08287.11 EAU89433.2 - 0.087 12.7 5.6 2.5 8.0 0.1 2.1 1 1 0 2 2 2 0 Spc19 Spectrin PF00435.21 EAU89433.2 - 0.12 12.8 1.6 0.23 12.0 1.6 1.4 1 0 0 1 1 1 0 Spectrin repeat BRE1 PF08647.11 EAU89433.2 - 0.24 11.5 5.2 0.89 9.7 3.2 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase VSG_B PF13206.6 EAU89433.2 - 0.7 9.1 3.2 1 8.5 3.2 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain ABC_tran_CTD PF16326.5 EAU89433.2 - 2.5 8.4 6.6 5.8 7.2 6.1 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain MASE1 PF05231.14 EAU89435.2 - 1.5 7.9 22.1 1.5e+03 -1.9 22.1 2.3 1 1 0 1 1 1 0 MASE1 DFP PF04127.15 EAU89436.1 - 1.5e-20 73.8 0.0 1.4e-12 47.9 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein PAS_9 PF13426.7 EAU89436.1 - 0.096 12.9 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 PAS domain Sec2p PF06428.11 EAU89437.1 - 3.3e-13 49.4 13.4 3.3e-13 49.4 13.4 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.11 EAU89437.1 - 0.0098 16.1 3.7 0.0098 16.1 3.7 4.2 3 2 0 4 4 4 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EAU89437.1 - 0.048 13.7 0.1 0.048 13.7 0.1 3.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.6 EAU89437.1 - 3.2 8.2 11.8 6.3 7.2 9.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Herpes_UL6 PF01763.16 EAU89437.1 - 3.9 5.9 10.6 0.095 11.2 2.6 1.9 1 1 1 2 2 2 0 Herpesvirus UL6 like CC2-LZ PF16516.5 EAU89437.1 - 6.8 7.1 16.0 12 6.4 6.8 3.1 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TolA_bind_tri PF16331.5 EAU89437.1 - 7.3 6.8 9.5 1.1 9.3 1.8 2.7 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF4763 PF15960.5 EAU89437.1 - 8.4 5.6 11.8 2.3 7.5 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Transferase PF02458.15 EAU89438.2 - 0.012 14.3 0.0 1.3 7.6 0.0 2.6 2 1 1 3 3 3 0 Transferase family ABC_tran PF00005.27 EAU89439.2 - 2.1e-32 112.5 0.1 8.1e-18 65.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 EAU89439.2 - 1e-13 50.8 4.9 2.5e-13 49.6 4.9 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EAU89439.2 - 2.5e-11 43.9 4.7 0.021 14.7 0.0 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU89439.2 - 2.5e-10 40.2 4.0 0.006 16.0 0.1 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 EAU89439.2 - 6.7e-07 28.9 3.2 6.7e-07 28.9 3.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 EAU89439.2 - 1.2e-05 25.8 0.0 0.24 11.8 0.0 2.7 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EAU89439.2 - 2.5e-05 24.7 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EAU89439.2 - 2.7e-05 24.1 0.0 0.25 11.2 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 EAU89439.2 - 8.6e-05 22.4 0.7 0.15 11.8 0.3 2.6 2 1 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EAU89439.2 - 0.00018 21.5 0.7 0.057 13.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EAU89439.2 - 0.00021 21.6 0.0 0.092 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EAU89439.2 - 0.00034 20.8 0.0 0.26 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 EAU89439.2 - 0.00054 19.9 2.2 0.00054 19.9 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 EAU89439.2 - 0.00075 19.2 0.2 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EAU89439.2 - 0.0012 18.6 0.1 0.29 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAU89439.2 - 0.0019 18.5 0.0 2.3 8.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EAU89439.2 - 0.0019 18.1 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_7 PF12838.7 EAU89439.2 - 0.0021 18.6 0.5 0.0021 18.6 0.5 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain NB-ARC PF00931.22 EAU89439.2 - 0.0022 17.2 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_10 PF13237.6 EAU89439.2 - 0.0031 17.6 14.9 0.0046 17.0 1.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain SRP54 PF00448.22 EAU89439.2 - 0.0037 16.9 1.7 0.84 9.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 EAU89439.2 - 0.0039 17.2 0.6 0.0039 17.2 0.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 EAU89439.2 - 0.0044 17.1 11.6 0.0087 16.2 11.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 EAU89439.2 - 0.0057 16.7 0.1 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_9 PF13187.6 EAU89439.2 - 0.0065 16.6 11.5 0.014 15.6 11.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_28 PF13521.6 EAU89439.2 - 0.0087 16.3 0.1 2.5 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EAU89439.2 - 0.009 16.6 0.0 1.9 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EAU89439.2 - 0.011 15.3 0.8 0.22 11.0 0.1 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EAU89439.2 - 0.015 15.5 0.0 6.2 7.1 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PUL PF08324.11 EAU89439.2 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 PUL domain AAA_5 PF07728.14 EAU89439.2 - 0.023 14.7 0.9 0.78 9.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_17 PF13534.6 EAU89439.2 - 0.023 15.2 0.1 0.023 15.2 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EAU89439.2 - 0.024 15.6 0.3 0.024 15.6 0.3 2.7 3 0 0 3 3 2 0 4Fe-4S double cluster binding domain VirE PF05272.11 EAU89439.2 - 0.056 13.2 0.0 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Roc PF08477.13 EAU89439.2 - 0.059 13.6 0.7 0.35 11.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EAU89439.2 - 0.069 12.9 0.4 7 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EAU89439.2 - 0.081 12.6 0.1 4.8 6.8 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase MMR_HSR1 PF01926.23 EAU89439.2 - 0.091 12.8 0.7 11 6.2 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 EAU89439.2 - 0.093 12.1 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 EAU89439.2 - 0.097 12.7 1.8 14 5.8 0.0 3.3 2 2 1 3 3 3 0 AAA domain AAA_13 PF13166.6 EAU89439.2 - 0.1 11.3 0.1 0.55 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 EAU89439.2 - 0.12 12.9 0.1 0.12 12.9 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EAU89439.2 - 0.35 11.5 12.6 0.11 13.0 1.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.15 EAU89439.2 - 0.56 10.1 1.9 53 3.7 0.1 3.2 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 EAU89439.2 - 1.2 9.6 11.8 0.31 11.5 0.4 2.9 2 1 0 2 2 2 0 AAA domain Rotamase_3 PF13616.6 EAU89440.2 - 1.4e-19 70.7 0.3 3.2e-19 69.6 0.3 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EAU89440.2 - 1.8e-16 60.9 0.1 2.9e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EAU89440.2 - 2.7e-05 25.0 0.2 4.6e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ribophorin_II PF05817.14 EAU89445.1 - 2.7e-36 125.4 0.0 3.2e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II COesterase PF00135.28 EAU89446.2 - 4.3e-89 299.7 0.0 6.9e-88 295.7 0.0 2.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU89446.2 - 1.9e-07 31.2 0.1 3.3e-06 27.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU89446.2 - 0.0028 17.1 0.2 0.0053 16.3 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family NDUFA12 PF05071.16 EAU89447.2 - 9.8e-09 35.9 3.4 3.5e-08 34.2 3.4 1.9 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF572 PF04502.13 EAU89447.2 - 0.02 14.6 1.3 0.026 14.2 1.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0449 PF15136.6 EAU89447.2 - 0.067 13.7 1.3 0.12 12.9 1.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 MscS_TM PF12794.7 EAU89448.2 - 0.036 12.9 5.6 0.053 12.4 5.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Trypan_PARP PF05887.11 EAU89449.2 - 0.15 12.0 3.3 0.16 12.0 3.3 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spore_coat_CotO PF14153.6 EAU89450.2 - 6.5 6.6 9.6 7.2 6.5 9.2 1.3 1 1 0 1 1 1 0 Spore coat protein CotO DUF5400 PF17379.2 EAU89452.2 - 1.3 9.5 7.9 1.3 9.5 1.8 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5400) XPG_I PF00867.18 EAU89453.2 - 9.7e-14 51.5 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EAU89453.2 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EAU89453.2 - 0.022 15.3 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Coatomer_WDAD PF04053.14 EAU89454.2 - 1.7e-139 465.7 0.0 3.6e-139 464.6 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EAU89454.2 - 2.1e-111 372.6 0.0 2.8e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EAU89454.2 - 1.7e-45 152.1 10.3 5.4e-08 33.4 0.2 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU89454.2 - 1.2e-11 44.7 0.4 0.027 14.8 0.0 6.0 4 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EAU89454.2 - 0.07 13.0 0.5 0.32 10.9 0.3 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.8 EAU89454.2 - 0.086 11.5 4.9 4.1 5.9 0.0 3.9 4 1 1 5 5 5 0 Nucleoporin Nup120/160 DUF5113 PF17140.4 EAU89455.2 - 0.041 13.7 0.5 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) TctB PF07331.11 EAU89455.2 - 0.28 11.4 3.7 0.63 10.3 3.7 1.5 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF4064 PF13273.6 EAU89455.2 - 0.61 10.4 5.0 1.1 9.5 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) CAP59_mtransfer PF11735.8 EAU89457.2 - 6.3e-69 232.3 0.0 7.8e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_M43 PF05572.13 EAU89462.2 - 1.2e-08 35.0 0.0 3.7e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EAU89462.2 - 1.5e-05 25.5 0.0 2.2e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EAU89462.2 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 EAU89462.2 - 0.015 14.3 0.7 0.022 13.7 0.7 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 EAU89462.2 - 0.059 12.6 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-zincin Reprolysin_2 PF13574.6 EAU89462.2 - 0.072 13.0 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU89462.2 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU89462.2 - 0.2 11.5 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin 2-oxoacid_dh PF00198.23 EAU89463.2 - 1.3e-83 280.1 0.1 1.7e-83 279.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAU89463.2 - 7.1e-19 67.4 2.2 1.4e-18 66.5 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EAU89463.2 - 1.8e-05 24.4 0.2 0.00032 20.5 0.2 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EAU89463.2 - 0.0002 22.0 0.3 0.22 12.2 0.0 2.5 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 EAU89463.2 - 0.0018 18.1 0.5 0.0045 16.9 0.5 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein RR_TM4-6 PF06459.12 EAU89463.2 - 7 6.4 8.6 10 5.9 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ABC_tran PF00005.27 EAU89464.2 - 2.6e-51 173.7 0.0 6.1e-31 107.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAU89464.2 - 4.5e-32 111.8 24.0 4.8e-26 92.0 7.0 3.5 4 1 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 EAU89464.2 - 1e-08 34.9 0.0 0.022 14.2 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU89464.2 - 0.0001 21.9 0.6 0.095 12.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EAU89464.2 - 0.001 18.9 1.2 3.6 7.3 0.4 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EAU89464.2 - 0.0014 18.9 0.2 3.1 8.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EAU89464.2 - 0.0034 17.0 0.1 2.7 7.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EAU89464.2 - 0.0068 15.5 0.0 0.4 9.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 EAU89464.2 - 0.011 16.2 0.6 6.2 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Mntp PF02659.15 EAU89464.2 - 0.026 14.3 0.3 0.084 12.6 0.3 1.9 1 0 0 1 1 1 0 Putative manganese efflux pump DUF87 PF01935.17 EAU89464.2 - 0.05 13.7 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain ATPase PF06745.13 EAU89464.2 - 0.052 12.9 0.6 9.4 5.5 0.1 2.3 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 EAU89464.2 - 0.14 11.3 0.2 1.9 7.6 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain MMR_HSR1 PF01926.23 EAU89464.2 - 0.16 12.1 0.4 1.7 8.7 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EAU89464.2 - 0.18 11.5 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EAU89464.2 - 0.38 11.1 2.8 4.8 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.19 EAU89464.2 - 0.7 9.5 3.2 1.3 8.6 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Oxidored_FMN PF00724.20 EAU89465.1 - 1.2e-58 199.1 0.0 3.6e-57 194.2 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF5308 PF17233.2 EAU89465.1 - 0.18 12.0 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) TPR_10 PF13374.6 EAU89466.2 - 8e-15 54.2 9.3 0.0021 17.9 0.3 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAU89466.2 - 1.4e-05 25.0 0.3 0.21 11.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU89466.2 - 0.00029 20.4 6.5 0.65 9.7 0.0 6.0 7 0 0 7 7 7 1 TPR repeat TPR_2 PF07719.17 EAU89466.2 - 0.0003 20.7 6.9 2.6 8.4 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU89466.2 - 0.00034 20.8 12.1 0.0039 17.4 1.2 5.4 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU89466.2 - 0.0014 18.3 7.7 3.1 7.8 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAU89466.2 - 0.07 13.8 1.9 22 6.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat FRB_dom PF08771.11 EAU89466.2 - 0.21 12.0 3.7 12 6.4 0.0 4.6 4 2 1 5 5 5 0 FKBP12-rapamycin binding domain 5_3_exonuc_N PF02739.16 EAU89466.2 - 0.48 10.3 1.4 6.2 6.7 0.3 2.4 1 1 1 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Zn_clus PF00172.18 EAU89467.2 - 0.0048 17.0 15.6 0.0074 16.4 15.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hemerythrin PF01814.23 EAU89470.2 - 5.3e-11 43.2 3.9 8.3e-11 42.6 3.9 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4419 PF14388.6 EAU89470.2 - 0.026 13.9 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) TCTP PF00838.17 EAU89470.2 - 0.038 14.3 0.2 0.045 14.1 0.2 1.2 1 0 0 1 1 1 0 Translationally controlled tumour protein CNTF PF01110.17 EAU89470.2 - 0.054 12.9 0.3 0.072 12.5 0.3 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor MFS_1 PF07690.16 EAU89471.2 - 4.8e-28 98.1 32.3 4.8e-28 98.1 32.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF308 PF03729.13 EAU89471.2 - 1.8 8.9 13.6 0.051 13.9 2.0 3.4 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF4962 PF16332.5 EAU89472.2 - 0.00041 19.0 2.2 0.00081 18.0 2.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4962) ABC_tran PF00005.27 EAU89473.2 - 1.1e-48 165.3 0.0 5.8e-30 104.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAU89473.2 - 7.6e-30 104.5 16.7 5.3e-18 65.6 2.6 3.9 3 1 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EAU89473.2 - 3.3e-09 36.5 0.6 0.0042 16.5 0.5 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU89473.2 - 0.00022 20.9 0.6 0.21 11.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAU89473.2 - 0.0012 19.1 0.1 3.9 7.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EAU89473.2 - 0.0032 18.0 0.1 2.3 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EAU89473.2 - 0.013 15.0 0.0 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAU89473.2 - 0.039 14.1 0.0 0.087 12.9 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 EAU89473.2 - 0.057 12.5 0.0 6.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FKBP_N_2 PF18023.1 EAU89473.2 - 0.077 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 BDBT FKBP like N-terminal IstB_IS21 PF01695.17 EAU89473.2 - 0.11 12.2 0.0 13 5.4 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 EAU89473.2 - 0.13 11.9 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EAU89473.2 - 0.14 11.5 0.2 17 4.7 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 EAU89473.2 - 0.19 12.1 0.4 5.5 7.4 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 EAU89473.2 - 0.23 10.7 0.1 6.4 5.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 EAU89473.2 - 0.83 9.2 2.2 1.4 8.5 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 EAU89473.2 - 3.6 7.3 5.1 72 3.0 0.1 3.6 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system BatA PF07584.11 EAU89474.1 - 0.011 16.1 0.3 0.023 15.1 0.3 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF3397 PF11877.8 EAU89474.1 - 0.02 15.1 0.4 0.031 14.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) FeoB_associated PF12669.7 EAU89474.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein CsbD PF05532.12 EAU89476.1 - 1.6e-15 56.7 8.8 2.8e-09 36.7 0.8 2.1 1 1 1 2 2 2 2 CsbD-like Aldedh PF00171.22 EAU89477.1 - 2.6e-87 293.3 0.0 3.1e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EAU89477.1 - 0.0071 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) O-FucT PF10250.9 EAU89478.2 - 9.8e-13 48.5 0.0 2.2e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RRM_1 PF00076.22 EAU89480.2 - 6.7e-29 99.5 0.0 8.2e-14 51.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3932 PF13068.6 EAU89480.2 - 0.094 13.0 0.0 4.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) MMR_HSR1 PF01926.23 EAU89481.2 - 3.4e-11 43.2 0.0 5.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU89481.2 - 3.7e-09 36.2 0.0 5.4e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EAU89481.2 - 5.2e-06 26.6 2.6 0.018 15.1 0.1 2.6 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EAU89481.2 - 1.4e-05 25.0 2.8 4.4e-05 23.4 0.8 2.4 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EAU89481.2 - 8.5e-05 23.1 0.0 0.00015 22.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter GBP PF02263.19 EAU89481.2 - 0.00058 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Septin PF00735.18 EAU89481.2 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EAU89481.2 - 0.014 15.7 0.1 0.07 13.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EAU89481.2 - 0.026 13.7 0.1 0.052 12.7 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EAU89481.2 - 0.083 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU89481.2 - 0.088 13.2 0.2 0.15 12.4 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EAU89481.2 - 0.093 13.2 2.5 0.77 10.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EAU89481.2 - 0.096 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EAU89481.2 - 0.12 12.4 0.1 0.41 10.7 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EAU89481.2 - 0.12 12.0 0.3 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAU89481.2 - 0.13 12.2 0.3 0.3 11.0 0.3 1.6 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EAU89481.2 - 0.16 12.4 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EAU89481.2 - 0.24 11.6 1.0 2 8.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain GFA PF04828.14 EAU89484.1 - 6.6e-18 64.8 0.1 9e-18 64.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme UPF0220 PF05255.11 EAU89485.1 - 7.2e-54 181.8 0.1 8.8e-54 181.5 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Oxidored_FMN PF00724.20 EAU89487.1 - 3.3e-69 233.8 0.0 3.9e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5638 PF18688.1 EAU89487.1 - 0.039 14.3 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5638) AP_endonuc_2 PF01261.24 EAU89487.1 - 0.072 12.5 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Arrestin_N PF00339.29 EAU89489.2 - 0.00018 21.6 3.0 0.23 11.5 0.9 3.9 3 1 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 EAU89490.1 - 2.4e-06 27.7 0.0 1.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Metallophos PF00149.28 EAU89491.1 - 2.9e-13 50.8 0.1 4.2e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.26 EAU89492.1 - 1e-28 99.9 1.0 1.6e-28 99.3 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU89492.1 - 8.2e-27 93.2 2.9 1.5e-26 92.4 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EAU89492.1 - 5e-06 27.6 0.2 8e-06 26.9 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_8 PF13183.6 EAU89492.1 - 0.043 14.3 1.3 6.6 7.3 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Malic_M PF03949.15 EAU89493.2 - 6.3e-90 300.9 0.0 8.2e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EAU89493.2 - 1.5e-65 220.4 0.0 8.2e-42 143.1 0.0 2.3 2 0 0 2 2 2 2 Malic enzyme, N-terminal domain adh_short PF00106.25 EAU89495.2 - 3.6e-32 111.4 0.1 2.8e-31 108.5 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU89495.2 - 5.1e-23 81.8 1.7 1.1e-10 41.4 0.7 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU89495.2 - 4.1e-07 30.1 0.0 1.5e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EAU89495.2 - 0.00088 18.8 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EAU89496.1 - 4e-28 97.5 2.4 1e-27 96.2 2.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU89496.1 - 4e-21 75.4 0.0 6.6e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAU89496.1 - 4.6e-12 45.9 0.0 9.3e-08 31.8 0.0 2.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EAU89496.1 - 6.5e-07 30.5 0.0 1.8e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EAU89496.1 - 0.005 16.1 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 EAU89496.1 - 0.017 15.8 0.1 0.079 13.7 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EAU89496.1 - 0.033 14.8 0.0 0.076 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 EAU89496.1 - 0.036 13.7 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.13 EAU89496.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EAU89496.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Gp_dh_N PF00044.24 EAU89496.1 - 0.097 13.0 0.0 0.47 10.8 0.0 2.1 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Methyltransf_18 PF12847.7 EAU89496.1 - 0.12 12.2 0.2 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain TrkA_N PF02254.18 EAU89496.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Dus PF01207.17 EAU89497.2 - 8.5e-55 186.0 0.0 1e-54 185.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EAU89497.2 - 0.042 13.3 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein GRAB PF10375.9 EAU89498.2 - 4.8e-08 32.6 1.2 1.1e-07 31.5 1.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 EAU89498.2 - 6.3e-05 22.8 0.0 0.00023 21.0 0.0 2.0 1 0 0 1 1 1 1 GRIP domain GldM_N PF12081.8 EAU89498.2 - 0.094 12.8 16.5 0.78 9.8 8.4 2.4 1 1 1 2 2 2 0 GldM N-terminal domain Fez1 PF06818.15 EAU89498.2 - 0.33 11.4 47.4 0.26 11.7 23.4 3.2 1 1 2 3 3 3 0 Fez1 DUF1216 PF06746.11 EAU89498.2 - 0.43 10.6 6.4 0.4 10.7 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1216) DASH_Hsk3 PF08227.11 EAU89498.2 - 0.46 10.9 6.8 3.4 8.1 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like F-box PF00646.33 EAU89499.2 - 1.7e-06 27.7 1.4 4.9e-06 26.3 1.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU89499.2 - 2.1e-06 27.5 1.2 5.2e-06 26.2 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU89499.2 - 0.0024 17.7 0.4 0.0045 16.9 0.4 1.4 1 0 0 1 1 1 1 F-box FAM199X PF15814.5 EAU89499.2 - 0.22 10.5 0.5 0.39 9.7 0.5 1.3 1 0 0 1 1 1 0 Protein family FAM199X RNA_pol_3_Rpc31 PF11705.8 EAU89500.1 - 1.1e-22 81.4 7.6 1.6e-22 80.9 7.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RRM_1 PF00076.22 EAU89501.1 - 1e-14 54.1 0.0 1.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EAU89501.1 - 7.6e-08 32.8 0.5 7.6e-08 32.8 0.5 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 EAU89501.1 - 0.00098 18.9 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif Sterol_MT_C PF08498.10 EAU89502.1 - 1.2e-28 99.2 0.0 1.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 EAU89502.1 - 2.6e-19 69.5 0.0 4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU89502.1 - 2.8e-18 66.3 0.0 5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU89502.1 - 4.4e-17 62.6 0.0 8.2e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAU89502.1 - 1.1e-13 51.2 0.1 1.8e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EAU89502.1 - 4.3e-12 46.2 0.0 6.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU89502.1 - 9.4e-12 45.5 0.0 2.8e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU89502.1 - 1.9e-08 34.0 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EAU89502.1 - 7.3e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 EAU89502.1 - 0.00024 20.7 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 EAU89502.1 - 0.00064 19.0 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.14 EAU89502.1 - 0.00095 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltr_RsmB-F PF01189.17 EAU89502.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F UPF0020 PF01170.18 EAU89502.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.6 EAU89502.1 - 0.0038 18.2 0.0 0.013 16.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EAU89502.1 - 0.0043 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 EAU89502.1 - 0.0077 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EAU89502.1 - 0.027 13.9 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EAU89502.1 - 0.097 12.8 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase RrnaAD PF00398.20 EAU89502.1 - 0.22 10.6 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EAU89502.1 - 0.23 11.4 0.0 0.4 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TFIIA PF03153.13 EAU89503.2 - 0.12 12.4 19.9 0.2 11.6 19.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.6 EAU89503.2 - 0.72 10.4 20.6 1.1 9.9 20.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SPX PF03105.19 EAU89503.2 - 2.6 7.9 12.8 0.46 10.4 7.4 2.1 2 1 0 2 2 2 0 SPX domain PAT1 PF09770.9 EAU89503.2 - 7.2 4.7 20.2 2.3 6.4 17.6 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 UPF0492 PF15744.5 EAU89503.2 - 8.4 5.5 16.3 13 4.9 16.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Lin-8 PF03353.15 EAU89503.2 - 8.9 5.8 9.9 16 4.9 9.9 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SKN1 PF03935.15 EAU89504.2 - 1.3e-191 637.4 0.1 1.5e-191 637.2 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EAU89504.2 - 0.00039 19.9 0.0 0.058 12.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Arrestin_N PF00339.29 EAU89506.2 - 0.00024 21.2 5.7 0.00031 20.8 1.4 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SWIRM PF04433.17 EAU89507.2 - 1.1e-31 109.0 0.2 3.3e-31 107.5 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EAU89507.2 - 4e-20 71.5 12.9 8.4e-20 70.5 12.9 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EAU89507.2 - 1.9e-09 37.6 0.0 5.5e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU89507.2 - 9.4e-07 29.0 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EAU89507.2 - 7.4e-06 25.7 3.1 1.3e-05 24.9 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type HTH_37 PF13744.6 EAU89507.2 - 0.13 12.3 1.7 0.32 11.0 1.7 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Paramyxo_ncap PF00973.19 EAU89507.2 - 0.13 11.1 2.0 0.22 10.4 2.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein EF-hand_4 PF12763.7 EAU89508.1 - 5.4e-32 109.8 0.1 1.7e-10 40.8 0.0 3.9 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EAU89508.1 - 8.3e-07 28.1 0.0 0.0099 15.4 0.0 4.3 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 EAU89508.1 - 6.6e-06 26.5 2.9 1.2 9.6 0.0 4.3 4 0 0 4 4 3 2 EF-hand domain pair Cnn_1N PF07989.11 EAU89508.1 - 8.8e-06 25.8 49.9 0.0074 16.4 2.1 5.5 2 2 4 6 6 6 6 Centrosomin N-terminal motif 1 EF-hand_6 PF13405.6 EAU89508.1 - 8.7e-05 22.2 0.2 0.22 11.5 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain HSBP1 PF06825.12 EAU89508.1 - 8.9e-05 22.3 11.8 0.0015 18.3 1.4 4.0 2 1 1 3 3 3 2 Heat shock factor binding protein 1 Seryl_tRNA_N PF02403.22 EAU89508.1 - 0.00028 21.1 3.1 0.00028 21.1 3.1 4.7 1 1 3 4 4 3 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 EAU89508.1 - 0.017 15.4 57.1 0.06 13.6 23.1 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) EF-hand_8 PF13833.6 EAU89508.1 - 0.023 14.5 0.0 0.92 9.4 0.0 3.3 3 1 1 4 4 4 0 EF-hand domain pair KASH_CCD PF14662.6 EAU89508.1 - 0.028 14.2 60.9 0.48 10.2 26.7 4.1 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH FPP PF05911.11 EAU89508.1 - 0.034 12.4 35.5 0.053 11.7 35.5 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil TSC22 PF01166.18 EAU89508.1 - 0.04 14.2 0.9 0.04 14.2 0.9 7.3 4 1 4 8 8 8 0 TSC-22/dip/bun family GPHH PF16905.5 EAU89508.1 - 0.048 13.4 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Nuc_N PF14448.6 EAU89508.1 - 0.1 12.4 0.2 0.37 10.7 0.2 1.9 1 0 0 1 1 1 0 Nuclease N terminal Phage_GP20 PF06810.11 EAU89508.1 - 0.22 11.3 36.3 0.16 11.8 9.6 4.4 1 1 3 4 4 4 0 Phage minor structural protein GP20 DivIC PF04977.15 EAU89508.1 - 0.3 10.9 50.1 0.42 10.4 6.3 6.6 2 1 5 7 7 7 0 Septum formation initiator DUF4407 PF14362.6 EAU89508.1 - 1.2 8.4 40.0 0.071 12.4 17.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CdvA PF18822.1 EAU89508.1 - 1.4 8.8 36.7 1.7 8.5 13.3 5.5 3 1 1 4 4 4 0 CdvA-like coiled-coil domain TACC_C PF05010.14 EAU89508.1 - 1.5 8.6 43.7 1 9.1 22.4 3.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 EAU89508.1 - 3.6 6.9 55.0 0.32 10.3 8.8 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4686 PF15742.5 EAU89508.1 - 7.3 5.6 58.5 1.7e+02 1.1 58.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) FUSC PF04632.12 EAU89508.1 - 7.9 4.9 28.5 1.6 7.1 9.8 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.12 EAU89508.1 - 8.1 6.5 59.2 1.4 9.0 5.9 4.5 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EAU89508.1 - 8.6 5.3 49.9 2.6 7.0 21.7 3.9 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 EAU89508.1 - 9.3 6.3 61.2 7.7 6.5 12.4 3.9 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mito_carr PF00153.27 EAU89509.2 - 3e-65 216.2 1.5 6.4e-22 77.3 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Stn1 PF10451.9 EAU89509.2 - 1.2e-06 27.7 0.4 8.1e-06 25.0 0.4 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EAU89509.2 - 0.15 12.1 0.6 0.44 10.6 0.6 1.8 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Rad52_Rad22 PF04098.15 EAU89510.2 - 4.3e-59 198.8 0.1 8.2e-59 197.9 0.1 1.5 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ABC_tran PF00005.27 EAU89511.1 - 1.1e-49 168.5 0.0 3.6e-30 105.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EAU89511.1 - 1.6e-39 136.2 22.9 1.1e-21 77.7 6.9 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EAU89511.1 - 3.2e-09 36.6 1.5 0.0012 18.3 0.5 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU89511.1 - 9.6e-05 22.0 1.3 0.19 11.5 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EAU89511.1 - 0.0011 18.6 0.2 0.45 10.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EAU89511.1 - 0.0088 16.3 0.7 8.5 6.6 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_23 PF13476.6 EAU89511.1 - 0.015 15.8 0.6 6.5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EAU89511.1 - 0.057 12.8 0.3 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EAU89511.1 - 0.089 12.5 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EAU89511.1 - 0.091 12.8 0.1 0.091 12.8 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 EAU89511.1 - 0.095 13.1 0.6 2.4 8.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain ShK PF01549.24 EAU89512.2 - 9.9e-18 64.4 25.6 1.7e-09 38.0 6.6 2.9 3 0 0 3 3 3 2 ShK domain-like Homoserine_dh PF00742.19 EAU89513.1 - 1.5e-48 164.9 0.0 2.3e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EAU89513.1 - 2.9e-19 69.8 0.0 5.4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain SKN1 PF03935.15 EAU89514.2 - 9.2e-195 647.8 0.1 1.1e-194 647.5 0.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EAU89514.2 - 0.003 17.1 0.1 0.067 12.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 LRR19-TM PF15176.6 EAU89515.2 - 5.5 7.0 4.7 1.3 9.1 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain AIG1 PF04548.16 EAU89516.2 - 1.4e-09 37.6 0.0 2.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EAU89516.2 - 1.6e-07 31.4 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EAU89516.2 - 0.00043 19.7 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EAU89516.2 - 0.0005 20.2 0.1 0.92 9.5 0.0 3.2 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 EAU89516.2 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EAU89516.2 - 0.048 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EAU89516.2 - 0.12 12.9 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EAU89516.2 - 0.13 12.7 0.5 1.1 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAU89516.2 - 0.14 12.5 0.0 0.37 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain GAS PF13851.6 EAU89517.2 - 0.0047 16.3 29.5 0.24 10.7 4.1 3.1 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 EAU89517.2 - 0.0097 15.7 2.7 0.0097 15.7 2.7 3.0 1 1 1 3 3 3 1 Phage minor structural protein GP20 DUF4145 PF13643.6 EAU89517.2 - 0.17 12.0 1.8 0.37 10.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) SlyX PF04102.12 EAU89517.2 - 0.33 11.6 23.9 0.28 11.8 0.6 4.3 2 1 2 4 4 4 0 SlyX SOGA PF11365.8 EAU89517.2 - 0.36 12.0 22.5 9.5 7.4 13.7 3.2 1 1 1 2 2 2 0 Protein SOGA Macoilin PF09726.9 EAU89517.2 - 0.51 8.8 24.1 1.7 7.1 24.1 1.6 1 1 0 1 1 1 0 Macoilin family WD40_alt PF14077.6 EAU89517.2 - 0.68 9.9 8.2 0.71 9.8 0.6 2.9 3 0 0 3 3 3 0 Alternative WD40 repeat motif FlaC_arch PF05377.11 EAU89517.2 - 0.77 10.2 14.4 8.1 6.9 0.8 4.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 EAU89517.2 - 1.2 8.7 20.6 0.6 9.6 12.0 2.8 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 FlxA PF14282.6 EAU89517.2 - 1.3 9.0 16.1 0.61 10.1 1.8 3.2 2 1 1 3 3 3 0 FlxA-like protein Csm1_N PF18504.1 EAU89517.2 - 1.6 9.1 24.1 0.19 12.1 2.0 4.1 2 1 1 3 3 3 0 Csm1 N-terminal domain NPV_P10 PF05531.12 EAU89517.2 - 1.6 9.3 6.2 84 3.7 4.1 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EAU89517.2 - 1.6 9.4 20.8 1.4 9.6 5.3 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Fzo_mitofusin PF04799.13 EAU89517.2 - 2.1 7.9 13.3 0.31 10.6 0.3 3.0 2 1 1 3 3 3 0 fzo-like conserved region APG6_N PF17675.1 EAU89517.2 - 2.2 8.8 30.4 1.5 9.3 7.9 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 EAU89517.2 - 2.3 8.3 22.8 1.1 9.3 3.3 3.6 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.12 EAU89517.2 - 2.8 8.0 9.7 17 5.4 0.4 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DHR10 PF18595.1 EAU89517.2 - 3.3 7.8 35.4 1.1 9.3 1.9 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Tropomyosin_1 PF12718.7 EAU89517.2 - 3.3 7.9 23.9 8.8 6.5 3.8 3.1 1 1 1 3 3 3 0 Tropomyosin like Swi5 PF07061.11 EAU89517.2 - 4 7.6 14.5 3.5 7.8 0.7 3.6 4 0 0 4 4 3 0 Swi5 TMPIT PF07851.13 EAU89517.2 - 4 6.6 13.3 1.7 7.8 4.6 2.2 1 1 1 2 2 2 0 TMPIT-like protein PKcGMP_CC PF16808.5 EAU89517.2 - 6.8 6.6 11.3 13 5.7 0.2 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec2p PF06428.11 EAU89517.2 - 7 6.7 24.7 2.6 8.1 0.5 4.4 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 EAU89517.2 - 7.4 4.4 11.2 9.6 4.0 11.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_C50 PF03568.17 EAU89520.1 - 7.5e-134 446.8 0.0 2.3e-133 445.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family C50 TPR_8 PF13181.6 EAU89520.1 - 7.9e-07 28.8 6.0 0.65 10.4 0.0 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU89520.1 - 4.2e-06 26.9 18.4 0.00083 19.6 0.4 6.2 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU89520.1 - 3.1e-05 23.7 17.1 6.4 7.2 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAU89520.1 - 0.00012 21.5 3.6 0.39 10.0 0.2 3.9 3 1 1 4 4 4 2 MalT-like TPR region CHAT PF12770.7 EAU89520.1 - 0.021 14.2 0.0 1.4 8.2 0.0 2.5 1 1 0 1 1 1 0 CHAT domain TPR_14 PF13428.6 EAU89520.1 - 0.66 11.0 16.1 47 5.2 0.4 7.9 8 0 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU89520.1 - 0.73 10.1 3.6 80 3.6 0.1 4.4 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 UPF0184 PF03670.13 EAU89520.1 - 1.1 9.7 3.7 0.74 10.2 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) TPR_6 PF13174.6 EAU89520.1 - 3.9 8.3 0.0 3.9 8.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU89520.1 - 8.5 6.4 14.2 7.3 6.6 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU89522.1 - 9.4e-35 117.5 1.8 0.018 14.9 0.0 10.0 10 0 0 10 10 9 7 Tetratricopeptide repeat NACHT PF05729.12 EAU89522.1 - 1.5e-08 34.8 0.0 8.4e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TPR_2 PF07719.17 EAU89522.1 - 2.2e-07 30.5 1.1 1.5e+02 2.9 0.0 8.9 9 0 0 9 9 9 0 Tetratricopeptide repeat AAA_16 PF13191.6 EAU89522.1 - 1.7e-05 25.3 0.0 7.9e-05 23.1 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EAU89522.1 - 3.9e-05 23.7 0.0 7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EAU89522.1 - 0.00035 19.8 0.0 0.00069 18.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 EAU89522.1 - 0.0091 16.4 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 EAU89522.1 - 0.022 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAU89522.1 - 0.043 13.7 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 EAU89522.1 - 0.047 14.0 0.0 0.96 9.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EAU89522.1 - 0.05 13.9 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain She2p PF11435.8 EAU89522.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein She2p AAA_33 PF13671.6 EAU89522.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DnaB_bind PF10410.9 EAU89522.1 - 1 9.6 6.7 1.3e+02 2.8 0.0 5.9 7 0 0 7 7 7 0 DnaB-helicase binding domain of primase TPR_10 PF13374.6 EAU89523.2 - 9.7e-18 63.4 2.0 0.00076 19.3 0.0 8.1 7 1 1 8 8 8 3 Tetratricopeptide repeat NACHT PF05729.12 EAU89523.2 - 3.1e-07 30.5 0.0 6.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EAU89523.2 - 3.4e-05 23.9 0.0 5.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EAU89523.2 - 5e-05 23.7 0.0 0.0002 21.8 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EAU89523.2 - 7.6e-05 22.0 0.0 0.00018 20.8 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.17 EAU89523.2 - 0.00052 19.9 0.0 1.9e+02 2.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat RNA_helicase PF00910.22 EAU89523.2 - 0.0038 17.6 0.0 0.0094 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EAU89523.2 - 0.011 16.0 0.1 0.12 12.7 0.0 2.8 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 EAU89523.2 - 0.012 15.9 0.0 0.095 13.0 0.0 2.5 4 0 0 4 4 4 0 AAA domain TetR_C_31 PF17940.1 EAU89523.2 - 0.017 15.3 0.6 0.34 11.2 0.0 3.4 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NTPase_1 PF03266.15 EAU89523.2 - 0.018 15.0 0.1 0.087 12.7 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EAU89523.2 - 0.02 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAU89523.2 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EAU89523.2 - 0.081 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EAU89523.2 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Lustrin_cystein PF14625.6 EAU89525.2 - 0.0077 16.6 0.6 0.0099 16.2 0.6 1.2 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain PIF1 PF05970.14 EAU89526.2 - 9.9e-72 242.1 0.0 7.8e-70 235.8 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EAU89526.2 - 4e-39 134.8 0.0 1e-38 133.4 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAU89526.2 - 5.1e-14 52.4 0.0 1.8e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU89526.2 - 1.9e-05 25.1 0.0 0.00017 22.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 EAU89526.2 - 2e-05 22.7 0.0 0.032 12.2 0.0 2.1 2 0 0 2 2 2 2 Helicase Viral_helicase1 PF01443.18 EAU89526.2 - 2.7e-05 24.1 0.2 0.027 14.2 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EAU89526.2 - 0.00013 21.4 0.0 0.00074 18.9 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EAU89526.2 - 0.00014 22.3 0.0 0.00035 21.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 EAU89526.2 - 0.003 17.6 0.0 0.019 15.0 0.0 2.3 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EAU89526.2 - 0.016 15.6 0.0 0.064 13.7 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAU89526.2 - 0.021 15.0 0.1 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Phage_GPA PF05840.13 EAU89526.2 - 0.022 13.9 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) AAA_6 PF12774.7 EAU89526.2 - 0.028 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region CbiA PF01656.23 EAU89526.2 - 0.051 13.6 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EAU89526.2 - 0.058 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAU89526.2 - 0.065 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 EAU89526.2 - 0.079 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 EAU89526.2 - 0.082 12.7 0.1 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EAU89526.2 - 0.087 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 EAU89526.2 - 0.093 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EAU89526.2 - 0.098 12.7 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 EAU89526.2 - 0.13 11.9 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 1 0 Thymidylate kinase AAA_18 PF13238.6 EAU89526.2 - 0.16 12.6 0.0 0.52 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EAU89526.2 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KDZ PF18758.1 EAU89527.1 - 4.2e-56 190.1 0.1 7.1e-56 189.3 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU89527.1 - 7.3e-41 138.7 0.0 2.8e-40 136.8 0.0 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU89527.1 - 0.00013 22.1 0.0 0.00038 20.6 0.0 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Cauli_VI PF01693.16 EAU89530.1 - 3.3e-10 40.1 0.0 6.7e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF4611 PF15387.6 EAU89530.1 - 0.053 13.8 0.9 0.08 13.2 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4131 PF13567.6 EAU89533.1 - 0.063 12.9 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ISP3_C PF18045.1 EAU89533.1 - 0.26 11.2 0.0 0.96 9.3 0.0 1.8 2 0 0 2 2 2 0 ISP3 C-terminal Granulin PF00396.18 EAU89534.1 - 0.035 14.4 2.6 0.077 13.3 2.6 1.6 1 0 0 1 1 1 0 Granulin Lustrin_cystein PF14625.6 EAU89534.1 - 0.037 14.4 3.8 0.062 13.7 3.8 1.5 1 1 0 1 1 1 0 Lustrin, cysteine-rich repeated domain Glypican PF01153.19 EAU89534.1 - 0.15 10.9 0.4 0.16 10.8 0.4 1.1 1 0 0 1 1 1 0 Glypican Rho_N PF07498.12 EAU89536.2 - 7.6e-06 25.8 0.6 1.7e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain Armet PF10208.9 EAU89536.2 - 0.0083 16.1 0.0 0.99 9.3 0.1 2.2 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding DUF4518 PF15008.6 EAU89536.2 - 0.033 13.4 2.1 0.65 9.1 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) zf-C3HC4_3 PF13920.6 EAU89536.2 - 0.06 13.2 0.2 0.06 13.2 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 EAU89536.2 - 0.18 11.8 1.6 0.56 10.3 1.6 1.8 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF1682 PF07946.14 EAU89536.2 - 0.2 10.8 6.5 0.31 10.2 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PIEZO PF15917.5 EAU89536.2 - 0.84 9.1 5.3 1.2 8.5 5.3 1.2 1 0 0 1 1 1 0 Piezo Presenilin PF01080.17 EAU89536.2 - 0.94 8.2 8.9 1.3 7.7 8.9 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EAU89536.2 - 2.1 6.4 9.4 2.8 6.0 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 EAU89536.2 - 2.7 6.2 9.7 3.9 5.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein FYVE PF01363.21 EAU89536.2 - 4.9 7.4 7.9 16 5.8 7.9 1.8 1 1 0 1 1 1 0 FYVE zinc finger DREPP PF05558.12 EAU89536.2 - 6.4 6.6 12.8 10 6.0 12.8 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide His_Phos_1 PF00300.22 EAU89537.2 - 6.6e-18 65.1 0.2 1.7e-17 63.8 0.2 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sigma_reg_N PF13800.6 EAU89538.2 - 0.04 14.2 1.2 0.073 13.4 1.2 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Syntaxin-6_N PF09177.11 EAU89539.1 - 3.9e-28 97.9 10.7 4.6e-27 94.5 1.8 2.3 1 1 1 2 2 2 2 Syntaxin 6, N-terminal SNARE PF05739.19 EAU89539.1 - 5.8e-12 45.4 0.3 5.8e-12 45.4 0.3 2.1 2 0 0 2 2 2 1 SNARE domain Spc7 PF08317.11 EAU89539.1 - 0.00015 20.8 10.6 0.0023 16.9 2.6 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Use1 PF09753.9 EAU89539.1 - 0.00023 21.0 2.9 0.00023 21.0 2.9 2.4 1 1 2 3 3 3 1 Membrane fusion protein Use1 Prominin PF05478.11 EAU89539.1 - 0.0018 16.3 3.7 0.067 11.2 0.3 2.2 1 1 1 2 2 2 2 Prominin DUF4407 PF14362.6 EAU89539.1 - 0.003 17.0 9.2 0.078 12.3 9.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) DUF1640 PF07798.11 EAU89539.1 - 0.013 15.6 8.4 0.85 9.6 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) HisKA_3 PF07730.13 EAU89539.1 - 0.03 14.8 0.4 0.03 14.8 0.4 2.9 3 1 0 3 3 3 0 Histidine kinase Bacillus_HBL PF05791.11 EAU89539.1 - 0.034 14.0 5.0 0.68 9.7 0.1 3.1 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) FliJ PF02050.16 EAU89539.1 - 0.052 13.8 10.7 1.1 9.5 0.1 3.1 2 2 1 3 3 3 0 Flagellar FliJ protein DUF5082 PF16888.5 EAU89539.1 - 0.058 13.7 5.1 0.39 11.0 0.5 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF2207 PF09972.9 EAU89539.1 - 0.075 11.8 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4618 PF15397.6 EAU89539.1 - 0.11 11.9 8.9 1.5 8.2 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Phage_GP20 PF06810.11 EAU89539.1 - 0.17 11.7 7.8 0.72 9.7 0.4 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 XhlA PF10779.9 EAU89539.1 - 0.18 12.0 6.5 1.1 9.6 0.6 3.1 3 0 0 3 3 3 0 Haemolysin XhlA DUF1664 PF07889.12 EAU89539.1 - 0.19 11.8 9.0 2.5 8.2 1.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 EAU89539.1 - 0.22 11.0 11.5 0.063 12.7 2.5 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 EAU89539.1 - 0.25 11.8 8.5 20 5.7 0.1 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) NleF_casp_inhib PF16809.5 EAU89539.1 - 0.26 11.2 6.6 1.2 9.0 1.4 2.4 2 1 0 2 2 2 0 NleF caspase inhibitor DLP_helical PF18709.1 EAU89539.1 - 0.34 10.1 8.5 0.27 10.4 0.6 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain TMPIT PF07851.13 EAU89539.1 - 0.39 9.9 4.7 3 7.0 0.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein Laminin_II PF06009.12 EAU89539.1 - 0.47 10.5 9.3 0.16 12.0 0.4 2.9 2 1 1 3 3 3 0 Laminin Domain II IFT57 PF10498.9 EAU89539.1 - 0.58 9.1 8.0 2 7.3 1.5 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Jnk-SapK_ap_N PF09744.9 EAU89539.1 - 0.59 10.3 13.5 0.11 12.7 3.8 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2120 PF09893.9 EAU89539.1 - 0.92 9.6 4.0 1.4 9.0 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Golgin_A5 PF09787.9 EAU89539.1 - 0.92 8.9 14.4 1.1 8.6 4.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 COG2 PF06148.11 EAU89539.1 - 1.1 9.4 10.2 11 6.1 0.3 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 EAU89539.1 - 1.2 9.3 9.7 8.6 6.5 0.9 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 EAU89539.1 - 1.3 7.5 9.2 18 3.8 9.2 2.1 1 1 0 1 1 1 0 AAA domain DUF16 PF01519.16 EAU89539.1 - 1.5 9.3 6.3 1.7 9.2 0.7 2.7 2 1 1 3 3 3 0 Protein of unknown function DUF16 FAM167 PF11652.8 EAU89539.1 - 1.8 9.1 6.0 1.4 9.4 0.9 2.8 2 1 1 3 3 3 0 FAM167 Lebercilin PF15619.6 EAU89539.1 - 2 8.0 12.1 1 9.0 2.5 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease NPV_P10 PF05531.12 EAU89539.1 - 2.1 8.9 8.2 23 5.5 0.1 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cnn_1N PF07989.11 EAU89539.1 - 2.2 8.5 9.1 4.7 7.4 0.4 3.9 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Enkurin PF13864.6 EAU89539.1 - 4 8.0 10.1 20 5.7 0.4 3.3 2 2 0 2 2 2 0 Calmodulin-binding TPR_MLP1_2 PF07926.12 EAU89539.1 - 5.7 7.0 17.7 3.1 7.9 2.4 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein UPF0242 PF06785.11 EAU89539.1 - 6.2 6.9 12.3 1.8e+02 2.1 10.3 2.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EAU89539.1 - 6.9 7.4 15.5 33 5.2 0.9 4.0 2 2 1 3 3 3 0 SlyX TMF_DNA_bd PF12329.8 EAU89539.1 - 8.7 6.4 9.8 4.8 7.3 0.6 3.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PHD PF00628.29 EAU89540.2 - 2.5e-07 30.5 1.8 5.1e-07 29.5 1.8 1.5 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.24 EAU89540.2 - 3.7e-05 23.5 0.2 9.9e-05 22.2 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD_4 PF16866.5 EAU89540.2 - 0.01 15.9 1.0 0.028 14.5 1.0 1.8 1 0 0 1 1 1 0 PHD-finger FMO-like PF00743.19 EAU89541.1 - 8.1e-39 133.4 0.0 9.9e-29 100.1 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAU89541.1 - 3.1e-18 66.1 0.0 2e-13 50.3 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU89541.1 - 2.6e-08 34.0 0.0 3.2e-05 24.0 0.0 3.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EAU89541.1 - 4e-08 32.8 0.0 5.8e-07 29.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAU89541.1 - 2.4e-06 27.0 0.0 0.00049 19.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EAU89541.1 - 0.0018 18.5 0.0 0.022 15.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAU89541.1 - 0.0031 16.3 0.0 1.9 7.1 0.0 3.5 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.17 EAU89541.1 - 0.0083 15.4 2.5 0.023 13.9 0.1 2.3 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 EAU89541.1 - 0.024 13.9 0.7 3.3 6.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EAU89541.1 - 0.068 12.7 0.2 17 4.8 0.1 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Bac_luciferase PF00296.20 EAU89541.1 - 0.21 11.0 0.7 3.1 7.1 0.6 2.3 2 0 0 2 2 2 0 Luciferase-like monooxygenase NDUF_B5 PF09781.9 EAU89542.1 - 0.15 11.6 4.9 0.28 10.7 4.9 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit GREB1 PF15782.5 EAU89542.1 - 4.2 4.4 18.3 5.5 4.0 18.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 EAU89542.1 - 4.8 5.6 16.2 7.2 5.0 16.2 1.2 1 0 0 1 1 1 0 Macoilin family p450 PF00067.22 EAU89543.2 - 2.2e-57 194.8 0.0 4.5e-57 193.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Nop14 PF04147.12 EAU89544.1 - 0.016 13.4 6.2 0.021 13.1 6.2 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 EAU89544.1 - 0.074 11.6 9.3 0.11 11.1 9.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop25 PF09805.9 EAU89544.1 - 0.19 12.2 5.4 0.31 11.5 5.4 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) F-protein PF00469.20 EAU89544.1 - 0.72 9.4 3.4 1.2 8.6 3.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Roughex PF06020.11 EAU89544.1 - 0.82 8.7 11.4 0.35 9.9 7.5 1.9 2 0 0 2 2 2 0 Drosophila roughex protein BUD22 PF09073.10 EAU89544.1 - 1 8.7 7.2 1.5 8.1 7.2 1.2 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.16 EAU89544.1 - 1.2 8.3 4.7 2 7.6 4.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 EAU89544.1 - 3.7 5.5 20.1 5.1 5.1 20.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EAU89544.1 - 8.2 5.7 12.7 14 4.9 12.7 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EAU89544.1 - 9 5.6 16.8 14 5.0 16.8 1.1 1 0 0 1 1 1 0 SDA1 TPR_10 PF13374.6 EAU89546.2 - 6.6e-09 35.4 6.5 0.059 13.3 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat ATPase_2 PF01637.18 EAU89546.2 - 9.9e-06 25.6 0.0 2.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EAU89546.2 - 1.4e-05 25.1 0.0 3.8e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU89546.2 - 0.00047 20.6 0.0 0.0029 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU89546.2 - 0.0019 18.5 0.0 0.0063 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EAU89546.2 - 0.0041 16.4 0.0 0.0087 15.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EAU89546.2 - 0.008 15.9 0.0 0.031 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Interferon PF00143.19 EAU89546.2 - 0.011 15.9 0.4 0.035 14.3 0.0 2.0 2 0 0 2 2 2 0 Interferon alpha/beta domain RNA_helicase PF00910.22 EAU89546.2 - 0.011 16.1 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EAU89546.2 - 0.02 15.2 0.0 0.55 10.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain FA_FANCE PF11510.8 EAU89546.2 - 0.047 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE NTPase_1 PF03266.15 EAU89546.2 - 0.075 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NTPase Peptidase_C14 PF00656.22 EAU89549.1 - 6.1e-16 59.1 0.0 9.7e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Formyl_trans_N PF00551.19 EAU89550.2 - 1.8e-18 66.9 0.0 3.4e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EAU89550.2 - 1.9e-06 28.1 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF3470 PF11953.8 EAU89550.2 - 0.29 11.1 2.2 1.3 9.0 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3470) SH3_9 PF14604.6 EAU89551.1 - 3.3e-10 39.7 1.1 8.9e-10 38.3 1.1 1.8 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EAU89551.1 - 1.1e-09 37.8 0.4 8.1e-09 35.0 0.4 2.1 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAU89551.1 - 8.7e-09 34.9 0.2 2.5e-08 33.5 0.2 1.8 1 1 0 1 1 1 1 Variant SH3 domain RNA_pol_L_2 PF13656.6 EAU89553.2 - 2e-17 62.7 0.1 6.7e-16 57.8 0.1 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EAU89553.2 - 2.3e-05 23.7 0.0 0.00054 19.3 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ADH_zinc_N PF00107.26 EAU89554.2 - 1.1e-23 83.7 0.0 2e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU89554.2 - 2.1e-17 64.4 0.0 4.6e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU89554.2 - 1.9e-09 37.3 0.0 4.4e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EamA PF00892.20 EAU89555.1 - 8.7e-26 90.7 33.6 4.5e-17 62.5 12.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EAU89555.1 - 0.00022 20.7 10.0 0.00026 20.5 4.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family SPX PF03105.19 EAU89556.1 - 2.2 8.1 8.8 2.5 7.9 8.8 1.1 1 0 0 1 1 1 0 SPX domain Cu-oxidase PF00394.22 EAU89560.1 - 3.9e-46 157.1 0.0 1.2e-41 142.5 0.0 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU89560.1 - 4.9e-37 126.7 7.6 5.1e-34 117.0 0.2 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU89560.1 - 2.4e-35 121.1 1.3 3.1e-34 117.5 0.4 2.9 3 0 0 3 3 3 1 Multicopper oxidase Rep_fac-A_3 PF08661.11 EAU89561.1 - 6.5e-19 68.2 0.0 8e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 CMAS PF02353.20 EAU89562.2 - 4.9e-65 219.6 0.3 5.9e-65 219.3 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EAU89562.2 - 2.1e-11 44.3 0.0 1.1e-09 38.9 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU89562.2 - 2.9e-09 37.5 0.0 5.1e-08 33.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU89562.2 - 2.9e-08 33.7 0.0 5.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EAU89562.2 - 4e-06 26.5 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 EAU89562.2 - 1.9e-05 25.3 0.0 4.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU89562.2 - 0.0033 17.2 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU89562.2 - 0.0088 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EAU89562.2 - 0.017 14.9 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EAU89562.2 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Holin_SPP1 PF04688.13 EAU89562.2 - 0.13 12.4 0.1 0.13 12.4 0.1 1.8 2 0 0 2 2 2 0 SPP1 phage holin AA_permease_2 PF13520.6 EAU89563.2 - 5.1e-51 173.8 36.2 6.3e-51 173.5 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease 6PF2K PF01591.18 EAU89564.2 - 1.2e-61 207.8 0.0 1.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EAU89564.2 - 5.2e-24 85.0 0.0 1.6e-19 70.4 0.0 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EAU89564.2 - 3.6e-06 27.2 0.0 6.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Toprim_3 PF13362.6 EAU89564.2 - 0.025 14.9 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Toprim domain KTI12 PF08433.10 EAU89564.2 - 0.035 13.5 0.0 0.066 12.7 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.12 EAU89564.2 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 EAU89564.2 - 0.2 11.5 0.1 0.47 10.3 0.1 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase RRM_1 PF00076.22 EAU89565.1 - 4.5e-13 48.8 0.0 8e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EAU89565.1 - 9.2e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 TRL PF13146.6 EAU89565.1 - 0.042 14.1 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 TRL-like protein family RRM_occluded PF16842.5 EAU89565.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif TraI PF07057.11 EAU89566.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA helicase TraI Gram_pos_anchor PF00746.21 EAU89571.2 - 0.026 14.4 0.9 0.047 13.6 0.9 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Transport_MerF PF11431.8 EAU89571.2 - 0.047 13.6 0.9 0.071 13.0 0.9 1.2 1 0 0 1 1 1 0 Membrane transport protein MerF Sex_peptide PF08138.11 EAU89572.2 - 0.058 13.5 0.6 0.2 11.8 0.6 2.0 1 0 0 1 1 1 0 Sex peptide (SP) family Neurensin PF14927.6 EAU89572.2 - 0.12 12.1 0.2 0.79 9.4 0.0 2.4 3 0 0 3 3 3 0 Neurensin Sec23_trunk PF04811.15 EAU89573.2 - 6.4e-75 251.9 0.0 1.4e-74 250.8 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EAU89573.2 - 9e-29 100.1 0.1 1.8e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EAU89573.2 - 1.1e-25 89.5 0.2 2.3e-25 88.4 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EAU89573.2 - 2.2e-15 56.4 6.5 4.1e-15 55.5 6.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EAU89573.2 - 4e-13 49.1 0.1 1.3e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EAU89573.2 - 0.097 12.1 0.2 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain OPT PF03169.15 EAU89574.2 - 9.1e-70 236.0 29.0 1.7e-47 162.4 4.3 2.3 1 1 0 2 2 2 2 OPT oligopeptide transporter protein TBSV_P22 PF03558.13 EAU89574.2 - 0.21 11.0 0.0 0.67 9.4 0.0 1.7 2 0 0 2 2 2 0 TBSV core protein P21/P22 Cellulase PF00150.18 EAU89575.2 - 4.9e-07 29.5 0.0 1.1e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Na_H_Exchanger PF00999.21 EAU89576.1 - 1.2e-49 169.2 49.1 1.7e-49 168.6 49.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GTA_holin_3TM PF11351.8 EAU89578.1 - 0.066 13.8 0.3 0.14 12.7 0.1 1.6 1 1 1 2 2 2 0 Holin of 3TMs, for gene-transfer release HLH PF00010.26 EAU89579.2 - 1.9e-08 34.1 0.0 5.3e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 EAU89581.2 - 1.5e-25 89.9 27.5 5.8e-15 55.1 6.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4079 PF13301.6 EAU89581.2 - 7.6 6.7 10.2 1.4 9.0 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) Tyrosinase PF00264.20 EAU89582.1 - 2.5e-35 122.8 0.0 4.2e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase XPG_I PF00867.18 EAU89583.2 - 7.3e-19 67.9 0.0 3.2e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EAU89583.2 - 1.6e-08 34.9 0.0 1.5e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EAU89583.2 - 0.097 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 XPG domain containing DUF3435 PF11917.8 EAU89590.2 - 0.013 14.4 0.4 0.025 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) RXLR PF16810.5 EAU89590.2 - 0.074 13.5 0.1 0.32 11.4 0.1 2.1 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DEAD PF00270.29 EAU89591.2 - 5e-14 52.4 0.0 6.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAU89591.2 - 5.6e-05 23.2 0.0 8.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tet_JBP PF12851.7 EAU89594.2 - 3.8e-09 36.4 0.0 1.2e-07 31.4 0.0 2.2 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily DUF5466 PF17554.2 EAU89600.1 - 0.3 11.3 0.9 8.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5466) p450 PF00067.22 EAU89601.2 - 7.7e-67 226.0 0.0 1e-66 225.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.24 EAU89602.1 - 5.8e-36 124.8 0.0 7.6e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EAU89602.1 - 2.5e-10 40.4 0.9 6.4e-09 35.9 0.2 3.4 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EAU89602.1 - 0.0061 15.8 0.7 0.023 14.0 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EAU89602.1 - 0.07 12.4 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU89602.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NPCBM_assoc PF10633.9 EAU89603.1 - 0.07 13.4 0.8 0.22 11.8 0.0 2.2 3 1 1 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Dyp_perox PF04261.12 EAU89604.1 - 3.8e-07 29.4 0.0 1.7e-05 24.0 0.0 3.1 3 1 0 3 3 3 1 Dyp-type peroxidase family VWA PF00092.28 EAU89605.2 - 1.1e-07 32.3 0.0 1.8e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAU89605.2 - 5.8e-05 23.7 0.0 0.00013 22.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EAU89605.2 - 0.043 13.8 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain TrmO PF01980.16 EAU89605.2 - 0.087 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 tRNA-methyltransferase O MFS_1 PF07690.16 EAU89606.1 - 3.2e-29 102.0 23.8 5e-29 101.3 23.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU89606.1 - 3.7e-11 42.6 12.6 2.6e-10 39.7 12.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Ribosomal_L27A PF00828.19 EAU89607.1 - 6e-22 78.7 0.0 8.8e-22 78.1 0.0 1.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.6 EAU89608.1 - 1.8e-25 88.5 0.0 2.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EAU89608.1 - 4e-11 42.2 0.0 5.7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 EAU89608.1 - 0.028 14.6 0.0 0.048 13.9 0.0 1.3 1 0 0 1 1 1 0 Rio2, N-terminal IDO PF01231.18 EAU89610.2 - 1.9e-141 471.8 0.0 2.3e-141 471.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase MMR_HSR1 PF01926.23 EAU89611.2 - 8.7e-11 41.9 0.0 2.1e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU89611.2 - 0.0057 16.6 0.0 0.079 12.9 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EAU89611.2 - 0.0087 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EAU89611.2 - 0.02 15.3 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EAU89611.2 - 0.043 14.4 0.1 0.13 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EAU89611.2 - 0.045 12.8 0.1 0.091 11.8 0.1 1.5 1 0 0 1 1 1 0 MCM P-loop domain Septin PF00735.18 EAU89611.2 - 0.053 12.8 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.18 EAU89611.2 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arf PF00025.21 EAU89611.2 - 0.11 12.0 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.13 EAU89611.2 - 0.13 11.2 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pkinase PF00069.25 EAU89614.2 - 5.2e-64 216.1 0.0 8.6e-64 215.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89614.2 - 2.3e-33 115.6 0.0 3.9e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAU89614.2 - 0.0013 18.7 0.0 0.0043 17.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family PPR PF01535.20 EAU89615.1 - 0.0014 18.7 0.1 62 4.2 0.0 5.3 5 0 0 5 5 5 0 PPR repeat TPR_7 PF13176.6 EAU89615.1 - 0.074 13.1 1.2 0.3 11.2 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU89615.1 - 9.9 7.3 10.6 2.1 9.4 0.5 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat p450 PF00067.22 EAU89617.1 - 3e-59 201.0 0.0 5.4e-59 200.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU89618.2 - 6.1e-71 239.5 0.0 7.5e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EAU89619.2 - 2.1e-72 244.4 0.0 2.4e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Collectrin PF16959.5 EAU89620.2 - 0.061 13.1 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 Renal amino acid transporter ABC_membrane PF00664.23 EAU89622.2 - 2.6e-101 338.9 27.6 1.3e-50 172.5 8.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAU89622.2 - 3.4e-69 231.6 0.0 4.3e-33 114.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAU89622.2 - 4.3e-15 55.7 1.5 1.9e-05 24.2 0.3 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EAU89622.2 - 1.1e-07 31.0 0.5 0.0022 16.9 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EAU89622.2 - 1.9e-07 31.5 0.7 0.046 14.0 0.0 4.7 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EAU89622.2 - 4.4e-07 29.5 0.6 0.023 14.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU89622.2 - 8.6e-07 29.5 1.8 0.0034 17.8 0.1 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 EAU89622.2 - 3.9e-06 26.8 0.0 0.019 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EAU89622.2 - 1.1e-05 24.8 0.1 0.042 13.1 0.0 2.7 3 0 0 3 3 3 2 Zeta toxin AAA_21 PF13304.6 EAU89622.2 - 4.1e-05 23.5 0.5 0.082 12.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EAU89622.2 - 4.3e-05 23.3 0.4 0.67 9.6 0.3 3.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EAU89622.2 - 5.1e-05 23.2 0.1 0.35 10.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EAU89622.2 - 0.00023 20.5 0.0 0.075 12.2 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_7 PF12775.7 EAU89622.2 - 0.0011 18.6 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EAU89622.2 - 0.0037 17.0 0.2 3.5 7.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 EAU89622.2 - 0.0053 17.0 3.1 4.3 7.7 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EAU89622.2 - 0.011 15.9 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2628 PF10947.8 EAU89622.2 - 0.015 15.6 0.1 0.015 15.6 0.1 2.8 3 0 0 3 3 1 0 Protein of unknown function (DUF2628) DUF815 PF05673.13 EAU89622.2 - 0.018 14.2 0.0 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EAU89622.2 - 0.018 15.0 0.0 2.4 8.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EAU89622.2 - 0.019 15.5 0.0 2.5 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAU89622.2 - 0.022 15.3 0.0 4.6 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EAU89622.2 - 0.023 14.1 0.2 3.7 6.8 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EAU89622.2 - 0.026 14.8 0.0 6.4 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EAU89622.2 - 0.027 14.1 3.2 2.3 7.8 0.1 3.1 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.17 EAU89622.2 - 0.034 14.2 0.6 7.4 6.6 0.1 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EAU89622.2 - 0.049 13.7 0.0 6.7 6.8 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 EAU89622.2 - 0.089 12.7 0.0 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 EAU89622.2 - 0.12 12.0 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EAU89622.2 - 0.16 11.1 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain LMBR1 PF04791.16 EAU89622.2 - 0.29 10.0 4.7 0.25 10.2 1.7 2.3 2 0 0 2 2 2 0 LMBR1-like membrane protein p450 PF00067.22 EAU89623.1 - 1.4e-69 235.1 0.0 1.8e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_3 PF13920.6 EAU89624.2 - 5.4e-11 42.2 6.6 2.5e-09 36.8 2.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU89624.2 - 0.00023 21.0 1.3 0.00097 19.0 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU89624.2 - 0.0016 18.3 4.6 0.0016 18.3 4.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EAU89624.2 - 0.0026 18.0 6.5 0.0037 17.6 1.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EAU89624.2 - 0.0063 16.4 2.2 0.052 13.5 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU89624.2 - 0.54 10.3 4.7 14 5.8 0.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger CARMIL_C PF16000.5 EAU89624.2 - 5.7 6.5 10.3 0.87 9.2 6.0 1.9 2 0 0 2 2 2 0 CARMIL C-terminus Pkinase_fungal PF17667.1 EAU89625.1 - 1.2e-49 169.3 0.0 4.2e-31 108.1 0.0 3.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 EAU89626.1 - 1.2e-52 179.1 0.0 5.6e-31 107.7 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Kdo PF06293.14 EAU89626.1 - 0.037 13.4 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MR_MLE_C PF13378.6 EAU89627.2 - 7.6e-46 156.4 0.7 1.4e-44 152.3 0.3 2.4 2 1 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EAU89627.2 - 4.7e-06 26.8 0.0 1.5e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EAU89627.2 - 0.0049 16.0 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Peptidase_C25_C PF03785.14 EAU89627.2 - 0.0057 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family C25, C terminal ig-like domain Glyco_transf_8C PF08437.10 EAU89628.1 - 0.064 13.4 0.9 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal SARAF PF06682.12 EAU89630.1 - 0.03 14.0 0.2 0.053 13.2 0.2 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Secretin_N_2 PF07655.13 EAU89630.1 - 0.055 14.0 1.8 0.15 12.6 1.8 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain CE2_N PF17996.1 EAU89631.1 - 0.0014 18.6 0.2 0.011 15.8 0.1 2.5 2 2 0 2 2 2 1 Carbohydrate esterase 2 N-terminal FeoB_associated PF12669.7 EAU89631.1 - 0.0058 17.0 1.0 0.0092 16.4 1.0 1.3 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein MLANA PF14991.6 EAU89631.1 - 0.026 14.8 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein melan-A TMEMspv1-c74-12 PF11044.8 EAU89631.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CHB_HEX_C_1 PF13290.6 EAU89631.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain 7TM_GPCR_Srh PF10318.9 EAU89632.1 - 0.003 16.6 1.1 0.0036 16.4 1.1 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh Orf78 PF06024.12 EAU89632.1 - 0.0072 16.6 2.0 0.0085 16.4 0.6 1.7 2 0 0 2 2 2 1 Orf78 (ac78) Glycophorin_A PF01102.18 EAU89632.1 - 0.012 15.8 1.1 0.023 15.0 0.9 1.7 1 1 0 1 1 1 0 Glycophorin A RIFIN PF02009.16 EAU89632.1 - 0.014 15.3 0.8 0.023 14.6 0.8 1.4 1 0 0 1 1 1 0 Rifin STE3 PF02076.15 EAU89632.1 - 0.019 14.2 1.5 0.025 13.8 1.5 1.1 1 0 0 1 1 1 0 Pheromone A receptor Calcyon PF06387.11 EAU89632.1 - 0.063 13.3 0.8 0.1 12.5 0.8 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) TMEM154 PF15102.6 EAU89632.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family E1-E2_ATPase PF00122.20 EAU89632.1 - 0.16 11.4 2.1 1.1 8.8 0.2 2.1 2 0 0 2 2 2 0 E1-E2 ATPase Amnionless PF14828.6 EAU89632.1 - 0.63 8.8 2.0 0.53 9.1 0.7 1.4 1 1 1 2 2 2 0 Amnionless DUF4448 PF14610.6 EAU89632.1 - 0.7 9.6 3.2 0.41 10.4 0.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4448) ABC_tran_CTD PF16326.5 EAU89633.1 - 0.034 14.4 0.6 12 6.3 0.0 4.1 4 1 1 5 5 5 0 ABC transporter C-terminal domain SIS PF01380.22 EAU89635.1 - 3.6e-64 214.5 0.3 1.6e-33 115.4 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EAU89635.1 - 5.9e-17 62.1 0.0 1.3e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EAU89635.1 - 2e-12 47.1 0.0 6.7e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EAU89635.1 - 4.9e-05 22.4 0.0 8.4e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EAU89635.1 - 0.02 14.9 0.0 0.069 13.2 0.0 1.9 1 1 1 2 2 2 0 SIS domain InPase PF18823.1 EAU89635.1 - 0.067 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Inorganic Pyrophosphatase 3-PAP PF12578.8 EAU89638.1 - 0.045 13.5 0.3 0.083 12.6 0.3 1.4 1 0 0 1 1 1 0 Myotubularin-associated protein HMMR_C PF15908.5 EAU89639.2 - 0.14 12.4 0.1 0.18 12.1 0.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Alpha_kinase PF02816.18 EAU89640.1 - 1.3e-05 25.4 0.6 2.4e-05 24.5 0.3 1.5 2 0 0 2 2 2 1 Alpha-kinase family MraZ PF02381.18 EAU89640.1 - 0.068 13.2 0.0 0.084 12.9 0.0 1.1 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like ADH_zinc_N PF00107.26 EAU89641.1 - 1.3e-20 73.7 0.7 2.2e-20 73.0 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU89641.1 - 1.8e-08 34.2 0.2 3.5e-07 30.1 0.0 3.0 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EAU89641.1 - 0.0048 16.4 0.2 0.0072 15.8 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus adh_short PF00106.25 EAU89641.1 - 0.024 14.1 0.5 0.041 13.3 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 EAU89641.1 - 0.032 14.4 0.5 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal GFA PF04828.14 EAU89642.2 - 2.4e-16 59.8 8.1 8.3e-06 26.1 1.8 4.8 4 1 0 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.14 EAU89643.2 - 0.00015 22.0 1.7 0.00015 22.0 1.7 2.3 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF374 PF04028.13 EAU89643.2 - 0.19 11.3 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF374) NOB1_Zn_bind PF08772.11 EAU89643.2 - 0.25 11.5 2.7 0.57 10.4 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cu-oxidase PF00394.22 EAU89644.1 - 1e-47 162.2 0.0 3.7e-42 144.1 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU89644.1 - 2.6e-37 127.6 8.6 2.2e-35 121.4 0.1 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU89644.1 - 2.1e-34 118.1 1.0 3.4e-33 114.2 0.2 3.0 3 1 0 3 3 3 1 Multicopper oxidase TFIIE_alpha PF02002.17 EAU89646.2 - 2.7e-19 69.0 0.5 4.8e-19 68.2 0.5 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit RecO_N_2 PF13114.6 EAU89646.2 - 0.009 15.7 0.1 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 RecO N terminal TFIIE-A_C PF11521.8 EAU89646.2 - 0.055 13.8 0.0 0.055 13.8 0.0 2.5 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha Zn_Tnp_IS1595 PF12760.7 EAU89646.2 - 0.18 11.8 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EAU89646.2 - 0.18 11.8 0.3 21 5.2 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf_UBZ PF18439.1 EAU89646.2 - 0.24 11.0 1.1 2.5 7.8 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Glyco_hydro_10 PF00331.20 EAU89647.2 - 2.4e-85 286.5 0.1 2.9e-85 286.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EAU89647.2 - 4.6e-12 45.7 13.8 1.2e-11 44.3 13.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Fungus-induced PF10917.8 EAU89647.2 - 0.061 13.7 0.1 0.061 13.7 0.1 1.9 2 0 0 2 2 2 0 Fungus-induced protein Glyco_hydro_10 PF00331.20 EAU89648.2 - 2e-79 267.1 0.0 1.3e-40 139.6 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EAU89648.2 - 0.0061 16.5 4.1 0.013 15.4 4.1 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 EAU89649.2 - 1.8e-07 31.3 0.0 2.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Na_Ca_ex PF01699.24 EAU89650.2 - 1.1e-33 116.4 32.1 4.4e-17 62.4 10.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Cys_Met_Meta_PP PF01053.20 EAU89651.1 - 3.9e-25 88.2 0.0 5.4e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EAU89651.1 - 0.00024 20.4 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tox-ODYAM1 PF15642.6 EAU89651.1 - 0.027 13.5 0.1 0.04 12.9 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus CBS PF00571.28 EAU89652.2 - 5.5e-13 49.1 1.1 0.0046 17.4 0.0 3.4 3 0 0 3 3 3 3 CBS domain Lipase_3 PF01764.25 EAU89653.2 - 3.7e-20 72.2 0.0 6.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAU89653.2 - 0.0002 22.0 0.0 0.00032 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EAU89653.2 - 0.023 14.4 0.1 0.061 13.0 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Hydrolase_4 PF12146.8 EAU89653.2 - 0.06 12.6 0.0 0.098 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_C101 PF16218.5 EAU89654.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C101 Na_H_Exchanger PF00999.21 EAU89655.2 - 4.1e-27 95.0 31.2 2e-17 63.1 22.8 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Abhydrolase_1 PF00561.20 EAU89656.1 - 1.6e-18 67.3 0.0 5.4e-18 65.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU89656.1 - 4.7e-13 50.3 1.3 8.3e-13 49.4 1.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU89656.1 - 1.9e-08 33.9 0.0 7.8e-07 28.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EAU89656.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 EAU89656.1 - 0.0042 15.8 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family DLH PF01738.18 EAU89656.1 - 0.0059 16.2 0.0 0.048 13.2 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EAU89656.1 - 0.01 15.6 0.0 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EAU89656.1 - 0.086 12.7 0.0 1.2 9.0 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 EAU89656.1 - 0.097 12.8 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Rad51 PF08423.11 EAU89657.2 - 1.8e-07 30.7 0.0 1.2e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EAU89657.2 - 8e-07 28.6 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 EAU89657.2 - 9.8e-07 28.5 0.1 2e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 recA bacterial DNA recombination protein PAXNEB PF05625.11 EAU89657.2 - 0.042 13.0 0.7 0.084 12.0 0.1 1.7 2 0 0 2 2 2 0 PAXNEB protein CbiA PF01656.23 EAU89657.2 - 0.052 13.6 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SAM_2 PF07647.17 EAU89657.2 - 0.091 12.9 0.2 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) CNH PF00780.22 EAU89658.2 - 0.015 15.0 0.0 0.029 14.0 0.0 1.5 1 1 0 1 1 1 0 CNH domain Sema PF01403.19 EAU89658.2 - 0.036 12.9 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Sema domain WD40_like PF17005.5 EAU89658.2 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain RRM_1 PF00076.22 EAU89659.2 - 9.6e-24 83.0 0.0 8.2e-12 44.8 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAU89659.2 - 3.6e-05 23.4 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EAU89659.2 - 0.0094 16.1 0.0 7.6 6.8 0.0 3.0 3 0 0 3 3 3 2 BRCA1-associated protein 2 PIG-P PF08510.12 EAU89660.1 - 1.5e-35 121.7 6.8 1.8e-35 121.4 6.8 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EAU89660.1 - 0.12 12.7 12.5 0.43 10.9 12.6 1.8 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) XPG_N PF00752.17 EAU89661.2 - 2.4e-24 85.7 0.0 5.6e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EAU89661.2 - 1.3e-23 83.2 0.0 2.9e-23 82.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EAU89661.2 - 9.5e-06 25.3 0.0 3.9e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 EAU89661.2 - 1.2e-05 25.9 0.0 2.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 EAU89661.2 - 0.018 14.9 0.2 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU89661.2 - 0.02 15.0 0.3 0.054 13.6 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU89661.2 - 0.026 14.7 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU89661.2 - 0.18 12.7 0.1 0.68 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat 5-FTHF_cyc-lig PF01812.20 EAU89663.2 - 9.2e-21 74.5 0.0 1.2e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PAC3 PF10178.9 EAU89663.2 - 0.21 11.7 0.0 0.33 11.1 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 zf-C2H2 PF00096.26 EAU89664.2 - 8.6e-11 41.7 7.6 2.9e-06 27.4 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU89664.2 - 1.3e-06 28.7 4.6 0.00044 20.9 0.8 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EAU89664.2 - 0.00048 20.4 0.4 0.0017 18.7 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAU89664.2 - 0.0042 17.3 0.1 0.0042 17.3 0.1 2.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EAU89664.2 - 0.0083 16.1 0.1 0.024 14.6 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger ThiC-associated PF13667.6 EAU89664.2 - 0.06 13.2 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 ThiC-associated domain zf-H2C2_2 PF13465.6 EAU89664.2 - 0.11 13.0 13.4 0.66 10.5 0.2 4.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 EAU89664.2 - 0.22 11.6 3.6 0.28 11.2 0.4 2.4 2 0 0 2 2 2 0 BED zinc finger Glyco_hydro_16 PF00722.21 EAU89665.1 - 2.5e-40 137.8 1.0 4.4e-40 137.0 0.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EAU89665.1 - 0.004 17.6 12.1 0.004 17.6 12.1 1.9 2 0 0 2 2 2 1 Chitin recognition protein Metallophos PF00149.28 EAU89666.2 - 2.9e-09 37.7 1.8 5e-09 37.0 1.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lamp PF01299.17 EAU89666.2 - 0.22 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Pro_CA PF00484.19 EAU89668.1 - 2.5e-35 122.1 0.1 6.7e-34 117.4 0.1 2.2 1 1 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 EAU89669.2 - 5.6e-35 120.9 0.0 8e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase CDC45 PF02724.14 EAU89670.2 - 8.7 4.5 15.7 12 4.0 15.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 EAU89673.2 - 1.7e-48 163.1 4.9 3.3e-13 50.0 0.0 6.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU89673.2 - 6.9e-36 122.2 5.2 3e-10 40.4 0.1 8.6 4 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU89673.2 - 2.1e-29 98.3 1.9 0.0022 18.3 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EAU89673.2 - 7.9e-24 83.4 7.8 3.3e-05 24.1 0.1 7.2 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 EAU89673.2 - 7e-20 70.5 10.3 0.03 14.8 0.1 10.5 11 0 0 11 11 11 6 Ankyrin repeat AAA_30 PF13604.6 EAU89673.2 - 0.033 13.9 0.1 3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EAU89673.2 - 0.11 12.5 1.7 2.1 8.2 1.7 2.4 1 1 0 1 1 1 0 NACHT domain Ank_2 PF12796.7 EAU89674.2 - 1.6e-148 483.7 13.3 3.9e-16 59.4 0.0 14.7 5 3 8 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU89674.2 - 4.7e-124 403.3 15.1 7.9e-10 39.1 0.1 23.1 10 5 16 26 26 26 23 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU89674.2 - 4.4e-120 390.2 34.1 2.7e-10 40.3 0.1 22.8 10 8 14 24 24 24 23 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU89674.2 - 7.1e-97 305.6 14.7 5e-05 23.4 0.0 28.4 30 0 0 30 30 30 21 Ankyrin repeat Ank PF00023.30 EAU89674.2 - 2.1e-93 303.0 27.1 2.3e-05 24.6 0.1 28.1 30 0 0 30 30 30 18 Ankyrin repeat Ank_2 PF12796.7 EAU89676.2 - 4.2e-80 264.4 0.0 1.3e-11 44.9 0.0 9.8 5 3 5 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU89676.2 - 3.7e-58 193.2 9.1 7.5e-08 32.8 0.0 13.7 10 4 4 14 14 14 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU89676.2 - 1.9e-50 168.3 9.6 1.7e-05 25.0 0.1 12.5 7 2 6 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU89676.2 - 2.5e-42 138.0 3.8 0.056 14.0 0.0 16.5 16 0 0 16 16 16 10 Ankyrin repeat Ank PF00023.30 EAU89676.2 - 1.3e-40 136.1 4.9 0.0079 16.6 0.0 15.9 16 0 0 16 16 16 9 Ankyrin repeat NACHT PF05729.12 EAU89676.2 - 2.9e-07 30.6 0.1 6.7e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAU89676.2 - 1e-06 29.1 0.0 2.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU89676.2 - 2.4e-05 24.8 1.0 7.1e-05 23.2 1.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EAU89676.2 - 0.0014 17.9 0.0 0.0031 16.8 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain Ank_2 PF12796.7 EAU89677.1 - 1.3e-67 224.4 12.4 2.2e-16 60.2 0.2 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU89677.1 - 1.1e-49 166.1 13.5 2.9e-10 40.5 0.1 8.2 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU89677.1 - 5e-41 138.2 19.7 3.4e-08 33.6 0.0 8.1 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU89677.1 - 1.9e-33 110.7 2.9 0.0082 16.6 0.0 9.1 9 0 0 9 9 9 9 Ankyrin repeat Ank PF00023.30 EAU89677.1 - 1.9e-31 107.1 7.8 0.0035 17.7 0.1 9.1 9 0 0 9 9 9 8 Ankyrin repeat EphA2_TM PF14575.6 EAU89678.1 - 0.00034 21.4 0.0 0.00058 20.7 0.0 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 EAU89678.1 - 0.017 14.0 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Adeno_E3_CR2 PF02439.15 EAU89678.1 - 0.027 14.2 0.3 0.05 13.4 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EAU89678.1 - 0.032 13.6 3.5 0.063 12.7 3.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAM176 PF14851.6 EAU89678.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Syndecan PF01034.20 EAU89678.1 - 0.25 11.3 2.5 0.42 10.6 2.5 1.3 1 0 0 1 1 1 0 Syndecan domain Beta-APP PF03494.13 EAU89678.1 - 4.8 7.1 9.9 9.5 6.2 9.9 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Ank_2 PF12796.7 EAU89679.2 - 1.3e-71 237.2 15.5 1.8e-12 47.7 0.1 7.9 2 2 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU89679.2 - 4.2e-49 164.3 7.9 1.8e-07 31.5 0.0 10.2 4 3 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU89679.2 - 1.2e-41 140.2 8.1 1.7e-06 28.2 0.1 10.3 5 3 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU89679.2 - 4.7e-32 106.4 2.4 0.032 14.8 0.0 13.0 14 0 0 14 14 14 9 Ankyrin repeat Ank PF00023.30 EAU89679.2 - 6.3e-28 96.0 10.1 0.0081 16.6 0.0 12.6 14 0 0 14 14 14 8 Ankyrin repeat ABC2_membrane PF01061.24 EAU89680.2 - 4.5e-77 258.2 47.6 2.5e-40 138.1 21.0 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EAU89680.2 - 1.1e-38 132.9 0.0 8.9e-18 65.1 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EAU89680.2 - 4.2e-36 122.7 2.5 1.2e-29 102.1 0.1 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EAU89680.2 - 2.8e-18 66.3 0.2 1e-17 64.5 0.1 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EAU89680.2 - 2.7e-06 26.8 15.8 2.7e-06 26.8 15.8 3.5 2 2 1 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.6 EAU89680.2 - 4.3e-06 27.2 0.0 0.0031 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAU89680.2 - 4.3e-06 26.7 0.0 0.0003 20.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EAU89680.2 - 2e-05 24.3 0.0 0.0088 15.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EAU89680.2 - 3.8e-05 24.3 0.0 0.016 15.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU89680.2 - 6.8e-05 23.2 0.1 0.11 12.7 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAU89680.2 - 0.00098 19.4 0.1 2.2 8.5 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAU89680.2 - 0.0036 17.0 0.4 0.25 11.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain dNK PF01712.19 EAU89680.2 - 0.0054 16.6 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase MMR_HSR1 PF01926.23 EAU89680.2 - 0.0057 16.7 0.0 0.72 10.0 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 EAU89680.2 - 0.0062 16.0 0.0 0.2 11.0 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EAU89680.2 - 0.0084 16.0 0.0 0.34 10.8 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_21 PF13304.6 EAU89680.2 - 0.0098 15.7 0.1 4.7 6.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EAU89680.2 - 0.01 16.0 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EAU89680.2 - 0.018 14.7 0.1 0.94 9.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EAU89680.2 - 0.024 14.6 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 EAU89680.2 - 0.025 14.3 0.4 1.7 8.3 0.4 2.7 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 EAU89680.2 - 0.026 15.0 0.0 9.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF4059 PF13268.6 EAU89680.2 - 0.028 14.8 0.1 0.028 14.8 0.1 2.8 3 0 0 3 3 1 0 Protein of unknown function (DUF4059) TsaE PF02367.17 EAU89680.2 - 0.046 13.7 0.3 0.71 9.9 0.1 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EAU89680.2 - 0.073 12.3 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ABC2_membrane_2 PF12679.7 EAU89680.2 - 0.084 12.1 19.2 0.17 11.1 9.7 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_19 PF13245.6 EAU89680.2 - 0.088 13.1 0.3 7.3 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EAU89680.2 - 0.11 11.3 0.3 0.31 9.8 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 EAU89680.2 - 0.14 12.6 0.0 3.6 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EAU89680.2 - 0.17 12.3 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EAU89680.2 - 0.2 11.4 0.1 3.4 7.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EAU89680.2 - 0.23 10.7 0.0 11 5.2 0.1 2.3 2 0 0 2 2 2 0 Septin DUF4436 PF14494.6 EAU89682.2 - 9.2e-05 21.9 3.0 9.2e-05 21.9 3.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4436) DUF4395 PF14340.6 EAU89682.2 - 0.68 10.3 5.6 0.69 10.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4395) SMC_N PF02463.19 EAU89683.1 - 9.7e-63 211.5 0.0 3.6e-62 209.7 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EAU89683.1 - 9.9e-29 100.0 0.1 4e-28 98.1 0.1 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EAU89683.1 - 1.7e-13 51.1 0.3 9e-07 29.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAU89683.1 - 3.4e-09 37.5 25.6 3.4e-09 37.5 25.6 7.0 2 2 2 4 4 1 1 AAA domain AAA_29 PF13555.6 EAU89683.1 - 2.9e-07 30.1 0.0 6.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 EAU89683.1 - 4.3e-05 22.5 7.2 4.3e-05 22.5 7.2 6.7 3 2 4 7 7 7 3 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EAU89683.1 - 0.0015 18.6 10.1 0.0015 18.6 10.1 8.5 5 2 4 9 9 8 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EAU89683.1 - 0.0016 18.5 4.6 0.0016 18.5 4.6 7.7 3 2 4 8 8 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SbcCD_C PF13558.6 EAU89683.1 - 0.0021 18.3 0.0 0.011 16.0 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF1664 PF07889.12 EAU89683.1 - 0.088 12.9 50.4 0.059 13.4 1.5 7.3 5 2 2 7 7 7 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 EAU89683.1 - 0.094 13.2 0.0 0.094 13.2 0.0 5.7 5 2 0 5 5 4 0 ABC transporter DASH_Duo1 PF08651.10 EAU89683.1 - 0.63 9.9 7.5 0.5 10.2 0.5 4.3 4 2 1 5 5 5 0 DASH complex subunit Duo1 FlaC_arch PF05377.11 EAU89683.1 - 4.2 7.8 34.8 9.7 6.7 0.1 8.5 6 2 2 8 8 8 0 Flagella accessory protein C (FlaC) Aldo_ket_red PF00248.21 EAU89685.2 - 3.1e-46 157.9 0.0 2.4e-44 151.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CoA_binding_2 PF13380.6 EAU89685.2 - 0.14 12.7 0.2 25 5.4 0.0 3.1 2 1 1 3 3 3 0 CoA binding domain MIOX PF05153.15 EAU89686.1 - 1.4e-127 424.4 0.9 1.7e-127 424.2 0.9 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EAU89686.1 - 0.0033 17.6 0.0 0.039 14.2 0.0 2.2 2 0 0 2 2 2 1 HD domain UBD PF16455.5 EAU89686.1 - 0.02 15.1 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain HDOD PF08668.12 EAU89686.1 - 0.21 11.0 0.0 0.4 10.1 0.0 1.5 1 0 0 1 1 1 0 HDOD domain HAD PF12710.7 EAU89687.1 - 3.1e-21 76.6 0.0 5.3e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EAU89687.1 - 0.00067 19.1 0.0 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 EAU89687.1 - 0.0025 17.4 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EAU89687.1 - 0.0063 16.8 0.3 0.26 11.6 0.3 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Vps39_2 PF10367.9 EAU89689.1 - 6.2e-11 42.7 0.1 3.3e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EAU89689.1 - 3.5e-08 33.7 0.7 3.9e-06 27.1 0.0 3.6 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 EAU89689.1 - 0.00039 20.3 1.5 0.13 12.1 0.0 3.3 4 0 0 4 4 4 2 Region in Clathrin and VPS ESCRT-II PF05871.12 EAU89689.1 - 0.058 13.7 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 ESCRT-II complex subunit L27 PF02828.16 EAU89689.1 - 0.087 12.6 1.6 6.6 6.6 0.1 3.8 4 0 0 4 4 4 0 L27 domain Cnd1 PF12717.7 EAU89690.2 - 4.4e-51 173.1 3.4 1.3e-45 155.3 0.1 3.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EAU89690.2 - 5.6e-48 162.9 0.0 5.6e-48 162.9 0.0 4.9 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 EAU89690.2 - 2.8e-06 27.6 1.1 0.039 14.4 0.0 4.5 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EAU89690.2 - 4.6e-05 23.3 3.7 12 6.5 0.1 6.6 7 0 0 7 7 6 1 HEAT repeat Cnd3 PF12719.7 EAU89690.2 - 0.00011 21.5 1.8 0.049 12.8 0.3 3.3 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain CM_1 PF07736.11 EAU89690.2 - 0.0042 17.5 1.4 0.012 16.1 0.2 2.3 2 0 0 2 2 2 1 Chorismate mutase type I IFN-gamma PF00714.17 EAU89690.2 - 0.0043 16.9 0.4 4.5 7.1 0.0 3.1 2 0 0 2 2 2 2 Interferon gamma ENTH PF01417.20 EAU89690.2 - 0.0061 16.6 3.9 0.63 10.1 0.0 4.1 4 0 0 4 4 4 1 ENTH domain OrfA PF17495.2 EAU89690.2 - 0.054 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Vpr-like OrfA HEAT_EZ PF13513.6 EAU89690.2 - 0.13 12.8 2.4 39 4.9 0.0 4.6 6 0 0 6 6 4 0 HEAT-like repeat Arm_2 PF04826.13 EAU89690.2 - 0.13 11.7 2.3 0.13 11.8 0.3 1.9 2 0 0 2 2 2 0 Armadillo-like Ribosomal_S6e PF01092.19 EAU89691.1 - 1.1e-57 193.4 0.0 1.8e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 EAU89692.1 - 4.5e-31 106.7 0.0 9e-31 105.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EAU89692.1 - 3.4e-14 52.8 0.2 4.6e-14 52.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EAU89692.1 - 0.019 14.9 0.1 0.037 14.0 0.0 1.4 1 1 0 1 1 1 0 'Paired box' domain HTH_32 PF13565.6 EAU89692.1 - 0.047 14.3 0.0 0.088 13.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain DNA_pol_A_exo1 PF01612.20 EAU89694.2 - 0.014 15.1 0.0 1.4 8.6 0.0 2.3 1 1 1 2 2 2 0 3'-5' exonuclease PIP5K PF01504.18 EAU89695.2 - 3.4e-101 338.1 0.1 3.4e-101 338.1 0.1 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Sua5_yciO_yrdC PF01300.18 EAU89695.2 - 0.043 13.3 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 Telomere recombination Ank_2 PF12796.7 EAU89696.2 - 5.6e-63 209.5 0.1 4.3e-13 49.6 0.0 7.0 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU89696.2 - 4.2e-45 151.6 3.2 5.9e-13 49.0 0.0 8.3 4 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU89696.2 - 9.8e-39 126.9 2.2 0.0039 17.6 0.0 13.7 13 0 0 13 13 13 9 Ankyrin repeat Ank PF00023.30 EAU89696.2 - 6.2e-36 121.3 7.7 3.3e-05 24.1 0.0 12.5 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 EAU89696.2 - 6.9e-35 118.7 14.4 1.8e-07 31.3 0.5 10.6 4 2 8 12 12 12 8 Ankyrin repeats (many copies) NACHT PF05729.12 EAU89696.2 - 3.8e-07 30.2 0.1 1.2e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EAU89696.2 - 0.0001 22.6 0.0 0.0022 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU89696.2 - 0.00022 21.6 0.0 0.0011 19.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EAU89696.2 - 0.0036 16.5 0.0 0.023 13.9 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain RuvB_N PF05496.12 EAU89696.2 - 0.018 14.8 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EAU89696.2 - 0.021 14.5 0.0 0.31 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAU89696.2 - 0.029 14.8 0.0 0.46 10.9 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EAU89696.2 - 0.091 13.3 0.0 1.4 9.4 0.0 2.9 2 1 0 2 2 2 0 ABC transporter Pkinase_fungal PF17667.1 EAU89700.2 - 8.9e-13 47.8 1.0 6.3e-11 41.7 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU89700.2 - 2.5e-06 27.0 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain rve PF00665.26 EAU89702.2 - 0.00028 21.1 0.0 0.00066 19.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Alpha_kinase PF02816.18 EAU89703.2 - 7.6e-24 84.8 0.0 1.2e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family MAM33 PF02330.16 EAU89704.2 - 3e-70 236.5 1.6 3.5e-70 236.3 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein HHH_2 PF12826.7 EAU89704.2 - 0.15 12.2 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.22 EAU89705.2 - 1.3e-49 165.9 0.0 2.6e-16 59.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3343 PF11823.8 EAU89705.2 - 0.00042 19.7 0.0 0.003 17.0 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3343) Limkain-b1 PF11608.8 EAU89705.2 - 0.0012 18.8 0.0 0.04 14.0 0.0 3.0 3 0 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 EAU89705.2 - 0.0072 15.9 0.0 3.3 7.3 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAU89705.2 - 0.015 15.4 0.0 11 6.1 0.0 3.1 3 0 0 3 3 3 0 RNA binding motif Apt1 PF10351.9 EAU89705.2 - 9.9 4.9 11.0 13 4.5 11.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase_fungal PF17667.1 EAU89706.2 - 5.6e-48 163.7 0.0 1.6e-47 162.2 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89706.2 - 1.9e-06 27.4 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89707.2 - 3.1e-35 121.8 0.0 2.4e-34 118.8 0.0 2.0 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89707.2 - 4.7e-05 22.9 0.0 8.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU89707.2 - 0.1 12.5 0.0 0.31 10.9 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAU89709.2 - 9.5e-42 143.2 0.0 3.4e-41 141.4 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89709.2 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89710.2 - 2.7e-43 148.3 2.2 3.2e-43 148.1 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89710.2 - 6.7e-07 28.9 0.0 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89711.2 - 1.8e-30 106.1 0.0 3.4e-29 101.9 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89711.2 - 3.9e-05 23.1 0.0 7.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 EAU89712.2 - 8.6e-72 241.7 0.0 1.3e-71 241.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89712.2 - 4.6e-44 150.6 0.0 7e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EAU89712.2 - 2.3e-18 66.1 0.5 4.3e-15 55.7 0.1 2.6 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EAU89712.2 - 2e-08 33.9 0.1 3.8e-07 29.7 0.0 2.6 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EAU89712.2 - 0.01 15.2 0.0 0.097 12.0 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EAU89712.2 - 0.12 11.3 0.4 0.22 10.4 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Ebola_NP PF05505.12 EAU89712.2 - 0.13 10.6 2.0 0.2 9.9 2.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein APH PF01636.23 EAU89712.2 - 0.74 9.7 3.7 0.95 9.3 0.2 2.5 2 1 0 3 3 3 0 Phosphotransferase enzyme family DNA_pol_phi PF04931.13 EAU89712.2 - 1.2 7.1 4.9 1.9 6.5 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4746 PF15928.5 EAU89712.2 - 3.8 6.9 8.4 7.4 5.9 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) APG6_N PF17675.1 EAU89712.2 - 4.9 7.7 11.9 11 6.6 11.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 EAU89712.2 - 5.7 6.8 9.6 13 5.7 9.6 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Pkinase_fungal PF17667.1 EAU89716.2 - 3.6e-37 128.1 0.0 5.9e-36 124.1 0.0 2.3 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89716.2 - 2.1e-06 27.3 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain KDZ PF18758.1 EAU89719.2 - 2.9e-49 167.7 0.1 9.6e-49 166.0 0.1 2.0 1 1 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU89719.2 - 3e-31 107.8 0.2 7.4e-31 106.5 0.2 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU89719.2 - 1.5e-09 37.9 0.1 4.1e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EAU89719.2 - 5.8e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases Pkinase_fungal PF17667.1 EAU89720.2 - 8.4e-41 140.1 0.0 1.8e-38 132.4 0.0 3.0 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89720.2 - 1.5e-07 31.1 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EAU89720.2 - 0.09 12.4 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Pkinase_Tyr PF07714.17 EAU89720.2 - 0.22 10.8 0.1 0.55 9.5 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU89722.2 - 7.8e-43 146.8 0.0 1.6e-42 145.8 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89722.2 - 4.2e-07 29.6 0.0 7.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89722.2 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DEAD PF00270.29 EAU89723.2 - 1.8e-20 73.4 0.0 1.6e-18 67.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.10 EAU89723.2 - 2.2e-13 50.0 0.0 5.6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EAU89723.2 - 7.5e-12 45.8 4.3 2.5e-11 44.1 4.3 2.0 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 EAU89723.2 - 2.4e-08 34.3 0.0 9.4e-08 32.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Thioredoxin_4 PF13462.6 EAU89723.2 - 0.027 14.6 0.1 0.091 12.9 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin E1-E2_ATPase PF00122.20 EAU89725.1 - 9.9e-36 122.9 22.7 5.2e-29 101.0 1.0 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAU89725.1 - 1.6e-31 109.5 4.4 1.6e-31 109.5 4.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAU89725.1 - 7.2e-17 62.4 0.1 1.2e-15 58.4 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAU89725.1 - 1.3e-14 53.6 0.0 3.6e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EAU89725.1 - 2.4e-14 53.2 0.0 4.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU89725.1 - 0.00093 19.0 0.6 0.0062 16.3 0.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAU89725.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase_fungal PF17667.1 EAU89727.1 - 2.4e-36 125.4 0.0 8.1e-36 123.7 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89727.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89727.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU89728.1 - 1.1e-37 129.8 0.0 6.6e-37 127.2 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89728.1 - 1.4e-07 31.1 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89728.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase BTB PF00651.31 EAU89731.2 - 0.0055 16.9 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DZR PF12773.7 EAU89731.2 - 0.3 11.2 8.3 0.81 9.8 8.6 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF3309 PF11752.8 EAU89732.2 - 0.22 11.6 0.2 0.22 11.6 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3309) APH PF01636.23 EAU89737.2 - 4.3e-13 49.8 0.0 7.4e-12 45.7 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EAU89737.2 - 0.015 14.2 0.0 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Complex1_LYR_1 PF13232.6 EAU89741.1 - 0.017 15.7 0.1 0.035 14.7 0.1 1.6 1 0 0 1 1 1 0 Complex1_LYR-like Peptidase_C14 PF00656.22 EAU89742.2 - 2.5e-19 70.2 0.0 3.6e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Creatininase PF02633.14 EAU89742.2 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Creatinine amidohydrolase DUF5454 PF17535.2 EAU89742.2 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5454) HMG_box PF00505.19 EAU89745.1 - 4.8e-13 49.3 0.2 1.1e-12 48.2 0.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU89745.1 - 1.5e-05 25.5 0.0 4.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain Peptidase_C2 PF00648.21 EAU89746.2 - 8.4e-54 182.6 1.2 5.3e-53 180.0 1.2 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease Phage_TAC_8 PF10666.9 EAU89746.2 - 0.1 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 Peptidase_C2 PF00648.21 EAU89747.1 - 5e-59 199.7 0.7 6e-58 196.2 0.7 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease Viral_P18 PF04521.13 EAU89747.1 - 0.15 11.9 0.3 0.38 10.5 0.3 1.6 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Sigma_M_inh PF17453.2 EAU89748.2 - 0.17 12.3 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-M inhibitor Peptidase_C2 PF00648.21 EAU89751.2 - 4.4e-58 196.7 0.0 3.4e-57 193.8 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease WD40 PF00400.32 EAU89752.2 - 3.3e-11 43.5 9.1 0.00022 22.0 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU89752.2 - 2.8e-06 27.5 0.1 0.5 10.7 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SnoaL PF07366.12 EAU89753.1 - 0.013 15.3 0.4 2.3 8.0 0.0 2.4 2 1 1 3 3 3 0 SnoaL-like polyketide cyclase DUF5512 PF17631.2 EAU89753.1 - 0.029 14.4 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Glyco_hydro_61 PF03443.14 EAU89754.1 - 4.8e-52 176.9 0.0 5.6e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 EAU89755.2 - 2.6e-43 148.4 0.0 3.4e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HECT_2 PF09814.9 EAU89756.2 - 4.1e-50 170.7 0.0 6.3e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Wbp11 PF09429.10 EAU89756.2 - 0.51 10.8 7.9 1.6 9.2 7.9 1.9 1 0 0 1 1 1 0 WW domain binding protein 11 Cutinase PF01083.22 EAU89757.1 - 5.4e-37 127.5 0.0 6.2e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 EAU89757.1 - 0.00076 19.4 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.11 EAU89757.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.20 EAU89757.1 - 0.0043 17.2 0.0 0.0059 16.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain VirJ PF06057.11 EAU89757.1 - 0.0049 16.8 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 EAU89757.1 - 0.0091 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase PF00151.19 EAU89757.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Lipase DUF3246 PF11596.8 EAU89758.1 - 0.053 12.9 2.7 0.087 12.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Mid2 PF04478.12 EAU89759.2 - 0.044 13.6 0.1 0.081 12.7 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PPTA PF01239.22 EAU89761.2 - 1.5e-44 148.5 12.7 7e-09 35.1 0.0 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.6 EAU89761.2 - 0.068 13.8 0.6 28 5.4 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAU89761.2 - 0.2 12.1 2.8 2 8.9 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_20 PF00982.21 EAU89762.2 - 1.2e-145 485.8 0.1 3.3e-145 484.4 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EAU89762.2 - 4e-71 238.9 0.0 3.5e-70 235.8 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_6 PF13344.6 EAU89762.2 - 0.056 13.6 0.0 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase KDZ PF18758.1 EAU89764.2 - 1.5e-46 158.8 0.7 2.4e-46 158.2 0.7 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU89764.2 - 5.1e-22 78.1 0.1 1.6e-21 76.4 0.1 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU89764.2 - 0.0025 17.9 0.1 0.007 16.5 0.1 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases MtaB PF12176.8 EAU89768.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Pkinase_fungal PF17667.1 EAU89776.1 - 6.7e-20 71.2 0.1 3.5e-19 68.9 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89776.1 - 5.8e-07 29.1 0.0 8.4e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89776.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_C80 PF11713.8 EAU89778.2 - 1.1e-10 42.0 0.0 1.8 8.8 0.0 8.0 9 0 0 9 9 8 3 Peptidase C80 family Pepsin-I3 PF06394.13 EAU89778.2 - 3.7e-10 39.9 8.9 11 6.2 0.0 8.1 7 0 0 7 7 7 4 Pepsin inhibitor-3-like repeated domain PhoPQ_related PF10142.9 EAU89778.2 - 2.6e-07 29.7 9.9 1.2 7.7 0.0 6.8 8 0 0 8 8 8 3 PhoPQ-activated pathogenicity-related protein Bmp PF02608.14 EAU89778.2 - 3.8e-07 29.4 11.6 8.9 5.2 0.0 8.2 9 0 0 9 9 9 5 ABC transporter substrate-binding protein PnrA-like UPF0004 PF00919.20 EAU89778.2 - 0.00056 19.9 3.4 95 3.1 0.0 7.4 8 0 0 8 8 8 0 Uncharacterized protein family UPF0004 ITAM PF02189.15 EAU89778.2 - 0.0017 18.7 5.5 1.6e+02 3.0 0.0 6.2 6 0 0 6 6 6 0 Immunoreceptor tyrosine-based activation motif AAA_22 PF13401.6 EAU89778.2 - 0.006 16.9 0.0 17 5.7 0.0 6.1 7 1 0 7 7 7 0 AAA domain AXE1 PF05448.12 EAU89778.2 - 0.02 13.6 32.5 2.5 6.7 0.2 7.8 8 0 0 8 8 8 0 Acetyl xylan esterase (AXE1) DUF463 PF04317.12 EAU89778.2 - 0.047 12.6 21.6 22 3.8 0.1 7.7 8 0 0 8 8 8 0 YcjX-like family, DUF463 BPL_LplA_LipB_2 PF16917.5 EAU89778.2 - 0.11 12.0 1.1 59 3.1 0.0 3.6 3 0 0 3 3 3 0 Biotin/lipoate A/B protein ligase family Lipocalin_4 PF13648.6 EAU89778.2 - 0.6 11.1 16.9 1.6 9.8 0.1 6.9 8 0 0 8 8 7 0 Lipocalin-like domain AAA_29 PF13555.6 EAU89778.2 - 2.2 8.1 16.5 10 6.0 0.1 7.1 8 0 0 8 8 8 0 P-loop containing region of AAA domain Sterol_MT_C PF08498.10 EAU89778.2 - 3.4 8.0 4.2 3.1e+02 1.8 0.0 4.3 4 0 0 4 4 4 0 Sterol methyltransferase C-terminal Pkinase_fungal PF17667.1 EAU89780.2 - 2.6e-40 138.5 0.0 3.8e-38 131.3 0.0 2.3 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89780.2 - 4.5e-11 42.6 0.0 8.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89780.2 - 0.00045 19.6 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4776 PF16003.5 EAU89780.2 - 0.022 13.8 0.2 0.033 13.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Pkinase_fungal PF17667.1 EAU89781.2 - 1.6e-52 178.7 0.0 2.8e-52 177.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89781.2 - 3.4e-08 33.2 0.0 8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89781.2 - 0.045 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase HTH_56 PF18662.1 EAU89781.2 - 0.1 12.7 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 Cch helix turn helix domain Pkinase_fungal PF17667.1 EAU89782.2 - 7.1e-40 137.0 0.0 5.7e-22 78.1 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU89782.2 - 7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cutinase PF01083.22 EAU89783.1 - 4.4e-38 131.0 0.0 5e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 EAU89783.1 - 6.7e-05 22.8 0.0 8.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EAU89783.1 - 0.00024 20.7 0.1 0.00037 20.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PE-PPE PF08237.11 EAU89783.1 - 0.00031 20.4 0.1 0.00056 19.5 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 EAU89783.1 - 0.015 15.1 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 EAU89783.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Transferase PF02458.15 EAU89784.1 - 0.059 12.0 0.0 2.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Transferase family Pkinase_fungal PF17667.1 EAU89786.2 - 3e-39 135.0 0.0 8.5e-37 126.9 0.0 2.2 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89786.2 - 2.6e-10 40.1 0.0 5.4e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89792.2 - 1.3e-52 179.0 0.0 2.2e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89792.2 - 1.4e-07 31.2 0.0 3.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89792.2 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU89793.1 - 4.6e-44 150.8 0.0 9e-43 146.6 0.0 2.3 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89793.1 - 1.9e-07 30.7 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EAU89794.2 - 6e-15 55.4 11.0 3.4e-06 27.7 0.6 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU89794.2 - 0.00049 20.3 0.0 0.21 11.9 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_3_Rpc31 PF11705.8 EAU89797.2 - 0.23 11.7 9.6 0.088 13.0 4.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Pkinase_fungal PF17667.1 EAU89800.1 - 1.9e-23 83.0 0.6 3.1e-22 78.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89800.1 - 5.3e-08 32.6 0.0 9e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PIF1 PF05970.14 EAU89804.2 - 2e-29 102.9 0.3 5.6e-29 101.4 0.2 1.8 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 EAU89804.2 - 1e-15 57.9 1.1 5.4e-15 55.6 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU89804.2 - 4.8e-10 40.0 0.0 1.4e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EAU89804.2 - 0.00024 21.2 3.3 0.0029 17.6 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 EAU89804.2 - 0.0016 17.4 0.2 0.0033 16.4 0.2 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EAU89804.2 - 0.0099 16.3 0.2 0.042 14.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 EAU89804.2 - 0.018 14.7 0.0 0.018 14.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EAU89804.2 - 0.021 14.6 11.8 1.1 8.9 0.0 3.9 3 1 0 4 4 4 0 AAA domain MeaB PF03308.16 EAU89804.2 - 0.027 13.4 1.0 0.06 12.3 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Plasmod_Pvs28 PF06247.11 EAU89805.2 - 0.029 14.7 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Pvs28 EGF domain AT_hook PF02178.19 EAU89805.2 - 2.5 8.3 8.4 8.9 6.6 8.4 2.0 1 0 0 1 1 1 0 AT hook motif WD40 PF00400.32 EAU89806.1 - 3.9e-15 56.0 11.1 2.9e-06 27.9 0.6 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU89806.1 - 0.0003 21.0 0.0 0.18 12.1 0.0 3.5 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_fungal PF17667.1 EAU89807.2 - 2.6e-39 135.2 0.0 3.6e-37 128.1 0.0 2.3 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89807.2 - 8.8e-11 41.7 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89807.2 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase KDZ PF18758.1 EAU89810.2 - 0.012 15.2 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase CxC4 PF18717.1 EAU89810.2 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 EAU89813.2 - 3.5e-09 36.5 0.0 6.7e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily ArsA_ATPase PF02374.15 EAU89814.2 - 0.044 13.0 0.2 0.047 12.9 0.2 1.0 1 0 0 1 1 1 0 Anion-transporting ATPase RepC PF06504.11 EAU89815.2 - 0.032 13.4 0.0 0.035 13.3 0.0 1.0 1 0 0 1 1 1 0 Replication protein C (RepC) Jnk-SapK_ap_N PF09744.9 EAU89816.2 - 0.047 13.9 0.8 4.7 7.4 0.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SNARE PF05739.19 EAU89816.2 - 0.052 13.5 0.4 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 SNARE domain SlyX PF04102.12 EAU89818.2 - 0.0014 19.2 1.6 0.0014 19.2 1.6 2.9 4 0 0 4 4 2 1 SlyX DUF948 PF06103.11 EAU89818.2 - 0.0039 17.4 2.2 1.6 9.0 0.2 2.4 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 EAU89818.2 - 0.011 15.4 0.6 0.039 13.7 0.6 1.9 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.6 EAU89818.2 - 0.023 14.1 4.4 0.05 13.0 4.4 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ApoLp-III PF07464.11 EAU89818.2 - 0.025 14.7 4.3 0.073 13.2 4.3 1.7 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Cnn_1N PF07989.11 EAU89818.2 - 0.026 14.7 0.8 0.1 12.8 0.7 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TACC_C PF05010.14 EAU89818.2 - 0.037 13.8 4.2 0.099 12.4 4.2 1.6 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 EAU89818.2 - 0.038 12.9 3.4 0.061 12.2 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein MbeD_MobD PF04899.12 EAU89818.2 - 0.056 13.6 0.3 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 MbeD/MobD like Spectrin PF00435.21 EAU89818.2 - 0.1 13.1 2.1 0.28 11.7 1.8 1.9 1 1 0 1 1 1 0 Spectrin repeat bZIP_2 PF07716.15 EAU89818.2 - 0.1 12.7 0.6 0.31 11.2 0.6 1.9 1 0 0 1 1 1 0 Basic region leucine zipper L27_1 PF09058.10 EAU89818.2 - 0.11 12.5 1.1 0.31 11.0 0.5 2.1 2 0 0 2 2 2 0 L27_1 ZapB PF06005.12 EAU89818.2 - 0.11 12.9 3.3 0.23 11.9 0.4 2.7 2 0 0 2 2 2 0 Cell division protein ZapB ADIP PF11559.8 EAU89818.2 - 0.15 12.2 6.0 0.29 11.2 6.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Prominin PF05478.11 EAU89818.2 - 0.65 7.9 3.8 0.91 7.4 3.8 1.1 1 0 0 1 1 1 0 Prominin ALMT PF11744.8 EAU89818.2 - 9.3 5.0 6.8 0.75 8.6 0.2 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Pkinase_fungal PF17667.1 EAU89819.2 - 2.2e-30 105.7 0.0 4.1e-29 101.6 0.0 2.2 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89819.2 - 2.1e-07 30.6 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89820.2 - 2.2e-43 148.6 0.0 9.5e-24 83.9 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 EAU89820.2 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89821.2 - 3.4e-33 115.0 0.0 4.7e-30 104.7 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89821.2 - 6.5e-07 29.0 0.0 1.7e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Tet_JBP PF12851.7 EAU89821.2 - 0.00012 21.6 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily MMS19_C PF12460.8 EAU89821.2 - 0.1 11.7 0.1 0.28 10.2 0.1 1.6 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal GTF2I PF02946.14 EAU89823.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 GTF2I-like repeat CDC45 PF02724.14 EAU89823.1 - 0.045 12.0 5.0 0.061 11.6 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein HMG_box_2 PF09011.10 EAU89823.1 - 0.11 13.2 0.1 0.28 11.8 0.1 1.7 1 0 0 1 1 1 0 HMG-box domain Tropomyosin_1 PF12718.7 EAU89824.1 - 4.5e-05 23.6 10.6 0.0012 19.0 2.8 2.7 1 1 1 2 2 2 2 Tropomyosin like SKA2 PF16740.5 EAU89824.1 - 0.0012 18.6 0.2 0.0081 15.9 0.0 2.4 2 1 0 2 2 2 1 Spindle and kinetochore-associated protein 2 Tropomyosin PF00261.20 EAU89824.1 - 0.0025 17.2 15.8 0.012 15.0 15.8 2.1 1 1 0 1 1 1 1 Tropomyosin Vps54_N PF10475.9 EAU89824.1 - 0.003 16.9 0.8 0.0047 16.2 0.8 1.2 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Spectrin PF00435.21 EAU89824.1 - 0.0057 17.1 4.9 0.26 11.8 0.6 3.3 1 1 3 4 4 4 2 Spectrin repeat Elongin_A PF06881.11 EAU89824.1 - 0.0087 16.6 3.0 1.2 9.7 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Jnk-SapK_ap_N PF09744.9 EAU89824.1 - 0.031 14.5 9.7 0.36 11.0 7.6 2.9 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF1090 PF06476.12 EAU89824.1 - 0.042 14.0 5.3 3.3 7.9 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) DHR10 PF18595.1 EAU89824.1 - 0.051 13.6 13.3 0.56 10.3 1.5 3.2 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF3584 PF12128.8 EAU89824.1 - 0.057 10.9 7.5 0.085 10.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.19 EAU89824.1 - 0.069 11.1 4.4 0.16 9.8 2.6 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 EAU89824.1 - 0.095 13.0 10.1 0.43 10.9 2.7 3.8 1 1 3 4 4 4 0 ABC transporter C-terminal domain Prominin PF05478.11 EAU89824.1 - 0.12 10.3 0.7 0.18 9.7 0.7 1.2 1 0 0 1 1 1 0 Prominin Lebercilin PF15619.6 EAU89824.1 - 0.14 11.8 11.8 0.65 9.6 9.3 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 EAU89824.1 - 0.14 12.3 1.6 0.69 10.1 0.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Taxilin PF09728.9 EAU89824.1 - 0.16 11.1 5.8 0.83 8.8 0.3 2.4 1 1 0 2 2 2 0 Myosin-like coiled-coil protein BLOC1_2 PF10046.9 EAU89824.1 - 0.17 12.2 4.0 25 5.3 0.4 3.9 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 EAU89824.1 - 0.18 11.2 5.9 0.75 9.1 0.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.18 EAU89824.1 - 0.33 10.2 2.5 0.71 9.1 2.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_13 PF13166.6 EAU89824.1 - 0.35 9.5 2.8 0.65 8.6 2.8 1.4 1 0 0 1 1 1 0 AAA domain CEP209_CC5 PF16574.5 EAU89824.1 - 0.35 11.0 6.3 0.4 10.8 4.5 1.9 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF948 PF06103.11 EAU89824.1 - 0.37 11.1 4.9 1.2 9.4 1.7 2.9 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EAU89824.1 - 0.38 10.8 6.3 0.26 11.3 0.7 3.1 2 1 2 4 4 3 0 Laminin Domain II Spc7 PF08317.11 EAU89824.1 - 0.61 8.9 8.2 1.4 7.7 7.5 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4164 PF13747.6 EAU89824.1 - 0.9 9.9 15.3 2.2 8.6 2.9 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 EAU89824.1 - 0.91 9.6 12.2 0.3 11.1 1.7 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EAU89824.1 - 1 8.9 6.0 3.7 7.0 6.1 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EAU89824.1 - 1.1 9.4 3.8 14 5.8 1.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2959 PF11172.8 EAU89824.1 - 1.4 9.0 5.7 3.7 7.7 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) FlaC_arch PF05377.11 EAU89824.1 - 1.7 9.1 5.7 13 6.2 0.3 3.9 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Vac_Fusion PF02346.16 EAU89824.1 - 2.2 8.0 5.2 1.5 8.5 0.3 3.0 2 1 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 TolA_bind_tri PF16331.5 EAU89824.1 - 3.3 7.9 5.4 37 4.5 3.1 3.2 2 1 0 2 2 1 0 TolA binding protein trimerisation DUF4407 PF14362.6 EAU89824.1 - 3.8 6.8 7.9 55 3.0 7.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Muted PF14942.6 EAU89824.1 - 5.3 7.4 9.0 3.9 7.8 3.6 2.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein ZapB PF06005.12 EAU89824.1 - 6.5 7.3 8.0 1.3 9.5 0.9 3.1 2 2 0 2 2 2 0 Cell division protein ZapB UBM PF14377.6 EAU89825.2 - 0.021 14.2 0.6 0.14 11.6 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin binding region BLM10_mid PF16507.5 EAU89825.2 - 0.067 11.8 0.1 4.4 5.8 0.1 2.0 1 1 1 2 2 2 0 Proteasome-substrate-size regulator, mid region SRP-alpha_N PF04086.13 EAU89826.2 - 0.11 12.4 3.9 0.12 12.3 3.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SNF2_N PF00176.23 EAU89829.2 - 2.3e-65 220.6 0.0 4.6e-65 219.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EAU89829.2 - 4e-38 129.9 1.0 4e-38 129.9 1.0 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EAU89829.2 - 3.2e-31 108.3 1.3 3.2e-31 108.3 1.3 4.1 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 EAU89829.2 - 3.9e-18 65.8 0.0 2.4e-17 63.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU89829.2 - 5.5e-09 36.3 0.0 8.3e-08 32.4 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAU89829.2 - 1.4e-06 27.7 0.0 1.4e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EAU89829.2 - 3.2e-05 23.8 0.2 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.6 EAU89829.2 - 7.2e-05 23.2 6.4 7.2e-05 23.2 6.4 3.5 4 0 0 4 4 4 1 DNA-binding domain AAA_14 PF13173.6 EAU89829.2 - 0.0061 16.6 0.0 0.023 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EAU89829.2 - 0.019 14.2 2.7 0.022 14.0 0.3 2.3 2 1 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase PBP PF01161.20 EAU89834.1 - 4.6e-08 33.4 0.1 5.9e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_92 PF07971.12 EAU89835.2 - 8.3e-118 394.2 0.1 7.6e-93 311.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EAU89835.2 - 2.2e-59 201.3 0.7 8.1e-59 199.4 0.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain Nup188_C PF18378.1 EAU89836.2 - 0.07 12.0 2.0 0.066 12.0 0.5 1.6 1 1 1 2 2 2 0 Nuclear pore protein NUP188 C-terminal domain RicinB_lectin_2 PF14200.6 EAU89837.2 - 1.3e-08 35.5 0.3 0.0028 18.4 0.3 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like adh_short PF00106.25 EAU89838.1 - 3.9e-12 46.1 0.0 8.9e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU89838.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU89838.1 - 1.6e-05 24.9 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Pkinase_fungal PF17667.1 EAU89839.1 - 7e-43 146.9 0.0 2.2e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU89839.1 - 1.7e-09 37.4 0.0 2.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89840.1 - 2.2e-12 46.5 0.1 2.9e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase TauD PF02668.16 EAU89841.2 - 9.5e-21 74.8 0.0 1.4e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HMG_box PF00505.19 EAU89842.1 - 1.2e-09 38.4 8.8 8.1e-09 35.8 8.8 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU89842.1 - 5.3e-08 33.3 4.0 1.5e-07 31.9 4.0 1.7 1 0 0 1 1 1 1 HMG-box domain Pkinase_fungal PF17667.1 EAU89843.2 - 7.4e-30 104.0 0.0 1.3e-16 60.4 0.2 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU89843.2 - 0.0023 17.4 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89845.2 - 2.1e-18 66.3 0.0 3.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89845.2 - 5.8e-07 29.1 0.0 9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU89845.2 - 0.12 12.3 0.0 7.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family RepB-RCR_reg PF10723.9 EAU89851.2 - 0.037 14.0 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Replication regulatory protein RepB DUF4413 PF14372.6 EAU89851.2 - 0.13 12.6 0.1 0.42 11.0 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) PDZ_4 PF17816.1 EAU89851.2 - 0.13 12.6 0.0 21 5.5 0.0 2.4 2 0 0 2 2 2 0 PDZ domain NOA36 PF06524.12 EAU89851.2 - 9.2 5.5 8.4 15 4.8 8.4 1.2 1 0 0 1 1 1 0 NOA36 protein zf-CCHC_6 PF15288.6 EAU89852.2 - 0.048 13.5 0.6 0.048 13.5 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 EAU89852.2 - 0.049 13.7 4.2 0.049 13.7 4.2 2.7 1 1 2 3 3 3 0 Zinc knuckle Zn_ribbon_SprT PF17283.2 EAU89852.2 - 0.06 13.3 5.7 0.55 10.2 0.3 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EAU89852.2 - 0.27 11.4 3.5 1.7 8.9 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Desulfoferrod_N PF06397.12 EAU89852.2 - 0.71 9.5 4.5 2.3 7.9 0.4 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-CCHC_2 PF13696.6 EAU89852.2 - 1.1 9.1 14.0 2.5 8.0 2.7 3.1 2 2 0 2 2 2 0 Zinc knuckle HypA PF01155.19 EAU89852.2 - 1.1 9.3 2.8 1.6 8.8 2.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_3 PF13917.6 EAU89852.2 - 1.2 9.1 12.0 4.5 7.3 12.0 1.9 1 1 0 1 1 1 0 Zinc knuckle Pkinase_fungal PF17667.1 EAU89854.1 - 1.4e-17 63.6 0.0 1.7e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 EAU89855.2 - 2.5e-32 112.2 0.0 1.6e-15 56.8 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 EAU89855.2 - 1.9e-07 30.7 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89856.2 - 1.9e-33 115.8 0.0 1.5e-32 112.9 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89856.2 - 0.00067 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89857.1 - 3.1e-43 148.1 0.0 4.1e-42 144.4 0.0 2.2 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89857.1 - 5.1e-08 32.6 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89858.1 - 1.3e-50 172.4 1.7 1.5e-49 168.9 0.0 3.1 4 1 0 4 4 4 1 Fungal protein kinase Pkinase PF00069.25 EAU89858.1 - 3.7e-07 29.8 0.0 6.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89859.1 - 3.3e-44 151.3 0.5 1.6e-43 149.1 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89859.1 - 5.1e-05 22.8 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89860.1 - 6.6e-43 147.0 0.0 5e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU89860.1 - 3e-07 30.1 0.0 4.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain adh_short PF00106.25 EAU89862.1 - 5.9e-11 42.2 0.2 1.2e-09 37.9 0.2 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU89862.1 - 1.7e-06 27.8 0.1 2.8e-05 23.8 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU89862.1 - 2.6e-05 24.2 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Pkinase_fungal PF17667.1 EAU89864.2 - 2.1e-41 142.0 0.0 8.8e-41 140.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89864.2 - 2e-07 30.6 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89865.2 - 2.1e-25 89.3 0.2 5.3e-19 68.3 0.3 2.6 2 0 0 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 EAU89867.2 - 1.7e-40 139.1 0.0 1.4e-39 136.0 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89867.2 - 6e-08 32.4 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89868.2 - 1.1e-07 31.0 0.0 2.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PheRS_DBD2 PF18554.1 EAU89868.2 - 0.015 15.3 0.3 0.028 14.4 0.3 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 2 Pkinase_fungal PF17667.1 EAU89870.2 - 2.1e-42 145.4 0.0 8.9e-22 77.4 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 EAU89870.2 - 1.2e-06 28.0 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89872.1 - 2.8e-51 174.6 0.0 6.2e-51 173.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU89872.1 - 2.7e-07 30.2 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EAU89873.2 - 1.5e-40 139.2 0.0 2.1e-39 135.5 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89873.2 - 1e-08 34.9 0.0 1.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PsaM PF07465.13 EAU89874.2 - 0.072 12.8 3.0 0.21 11.3 3.0 1.8 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) DUF3134 PF11332.8 EAU89876.1 - 7.4 7.0 7.1 49 4.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) Glyco_hydro_30 PF02055.16 EAU89877.2 - 5.6e-27 94.6 0.0 7.4e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 EAU89877.2 - 1.2e-11 44.4 0.0 1.9e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EAU89877.2 - 0.0013 18.5 0.0 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 HMG_box PF00505.19 EAU89878.2 - 3.6e-13 49.7 0.6 6.7e-13 48.9 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU89878.2 - 0.00069 20.2 0.1 0.0016 19.0 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain Eisosome1 PF12757.7 EAU89878.2 - 0.08 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Eisosome protein 1 Pkinase_fungal PF17667.1 EAU89879.2 - 1.7e-34 119.3 0.0 2.4e-22 79.3 0.0 2.9 2 1 0 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 EAU89880.2 - 8.4e-53 179.6 0.1 5.7e-52 176.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89880.2 - 1.3e-07 31.3 0.0 3.1e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain DotA PF11388.8 EAU89880.2 - 0.065 13.4 0.3 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Phagosome trafficking protein DotA HTH_56 PF18662.1 EAU89880.2 - 0.11 12.6 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 Cch helix turn helix domain Peptidase_G2 PF11962.8 EAU89880.2 - 0.13 11.6 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase_G2, IMC autoproteolytic cleavage domain Pkinase_fungal PF17667.1 EAU89881.2 - 2e-38 132.3 0.1 1.8e-35 122.5 0.0 3.1 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89881.2 - 5.3e-09 35.8 0.0 9.7e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89881.2 - 0.016 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase TraC PF07820.12 EAU89882.2 - 0.081 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 TraC-like protein Pkinase_fungal PF17667.1 EAU89883.2 - 7.6e-39 133.6 0.0 3.8e-37 128.0 0.0 2.9 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EAU89883.2 - 7.7e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU89883.2 - 0.05 12.9 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase CENP-B_dimeris PF09026.10 EAU89885.2 - 0.15 12.4 1.6 0.33 11.4 1.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain KDZ PF18758.1 EAU89886.2 - 5.4e-46 157.0 0.1 1.1e-45 156.0 0.1 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU89886.2 - 2.6e-19 69.4 0.0 5.4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU89886.2 - 0.002 18.3 0.0 0.0053 16.9 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Rubredoxin_2 PF18073.1 EAU89886.2 - 3.6 7.4 12.5 3.4 7.5 5.6 2.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain DivIC PF04977.15 EAU89888.2 - 0.078 12.8 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator CCDC-167 PF15188.6 EAU89888.2 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4939 PF16297.5 EAU89889.2 - 5.9e-07 29.4 0.0 0.00076 19.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4939) VD10_N PF08476.10 EAU89889.2 - 6.1e-05 22.6 2.3 0.23 11.1 0.1 2.8 3 0 0 3 3 3 2 Viral D10 N-terminal Hormone_3 PF00159.18 EAU89889.2 - 0.081 13.0 6.5 5.2 7.2 0.1 3.8 4 0 0 4 4 4 0 Pancreatic hormone peptide Retrotrans_gag PF03732.17 EAU89889.2 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein Thiolase_N PF00108.23 EAU89891.1 - 3.1e-79 266.0 1.6 3.1e-79 266.0 1.6 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAU89891.1 - 1e-43 147.9 0.5 2.5e-43 146.6 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EAU89891.1 - 7.7e-05 22.4 1.1 0.0024 17.5 0.3 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ICMT PF04140.14 EAU89892.1 - 1e-10 41.9 0.4 6.9e-10 39.2 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAU89892.1 - 5.2e-07 30.0 0.8 6e-06 26.6 0.5 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EAU89892.1 - 1.7e-06 27.1 0.0 2.7e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Polysacc_deac_1 PF01522.21 EAU89893.2 - 7.2e-36 122.8 0.0 1.1e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase CBM_1 PF00734.18 EAU89893.2 - 1.3e-13 50.6 10.6 2.8e-13 49.6 10.6 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF2334 PF10096.9 EAU89893.2 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Toxin_7 PF05980.12 EAU89893.2 - 0.1 12.9 2.5 0.21 11.9 2.5 1.5 1 0 0 1 1 1 0 Toxin 7 Ank_2 PF12796.7 EAU89898.2 - 1.1e-32 112.5 0.0 1.3e-13 51.3 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU89898.2 - 2.7e-27 94.8 0.0 2.1e-05 24.9 0.1 6.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU89898.2 - 1.3e-25 88.6 1.2 3.6e-06 27.2 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EAU89898.2 - 8.1e-24 81.1 0.2 1.3e-06 28.3 0.0 7.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EAU89898.2 - 2.3e-23 81.9 3.1 1.1e-06 28.8 0.1 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU89898.2 - 2.1e-06 28.1 0.1 2.7e-05 24.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU89898.2 - 0.00014 21.9 0.1 0.00075 19.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 EAU89898.2 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EAU89898.2 - 0.052 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EAU89898.2 - 0.13 12.7 0.0 0.61 10.5 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ferric_reduct PF01794.19 EAU89899.2 - 2e-20 73.2 16.8 2e-20 73.2 16.8 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EAU89899.2 - 1.3e-06 28.6 0.4 0.066 13.3 0.1 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAU89899.2 - 0.0036 17.4 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EAU89899.2 - 0.057 14.1 0.1 0.24 12.1 0.1 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain YL1 PF05764.13 EAU89906.2 - 0.0028 17.8 1.8 0.0035 17.5 1.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DUF2398 PF09661.10 EAU89906.2 - 0.012 14.9 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) CDC45 PF02724.14 EAU89906.2 - 2.7 6.2 6.0 3.6 5.8 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EAU89906.2 - 9.2 4.2 9.4 11 3.9 9.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sugar_tr PF00083.24 EAU89907.2 - 1.1e-94 317.9 17.4 1.4e-94 317.6 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU89907.2 - 5.4e-30 104.5 44.9 3.8e-27 95.1 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EAU89907.2 - 0.0023 18.1 4.4 0.0024 18.1 1.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2530) DUF697 PF05128.12 EAU89907.2 - 0.08 12.6 0.2 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF697) zf-C2H2_jaz PF12171.8 EAU89908.2 - 1.5e-11 44.3 3.4 2.1e-11 43.8 3.4 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EAU89908.2 - 0.00099 19.4 0.1 0.0013 19.0 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EAU89908.2 - 0.0018 18.6 1.9 0.0027 18.0 1.9 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EAU89908.2 - 0.029 15.2 0.4 0.051 14.4 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Autophagy_C PF10381.9 EAU89908.2 - 0.28 10.7 0.5 0.5 9.9 0.5 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Nodulin_late PF07127.11 EAU89910.1 - 0.068 13.5 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 Late nodulin protein SLD3 PF08639.10 EAU89913.2 - 3e-08 32.9 7.9 3e-08 32.9 7.9 3.2 1 1 1 3 3 3 2 DNA replication regulator SLD3 F-box-like PF12937.7 EAU89914.1 - 0.004 17.0 0.3 0.004 17.0 0.3 2.2 2 0 0 2 2 2 1 F-box-like Synaptonemal_3 PF15191.6 EAU89914.1 - 0.064 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 F-box_4 PF15966.5 EAU89914.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.9 1 1 0 1 1 1 0 F-box ArgJ PF01960.18 EAU89919.1 - 1.9e-145 484.3 0.6 2.2e-145 484.1 0.6 1.0 1 0 0 1 1 1 1 ArgJ family Saf_2TM PF18303.1 EAU89932.2 - 0.65 9.6 4.4 1.7 8.2 4.4 1.7 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain MFS_1 PF07690.16 EAU89933.2 - 1.8e-28 99.5 25.3 1.2e-27 96.8 26.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 EAU89934.2 - 5.8e-27 94.5 26.9 3.5e-26 92.0 28.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PMP1_2 PF08114.11 EAU89934.2 - 0.75 9.6 5.4 0.32 10.8 0.2 2.7 2 0 0 2 2 2 0 ATPase proteolipid family NCD3G PF07562.14 EAU89936.1 - 0.043 13.8 0.3 0.072 13.1 0.3 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Mid2 PF04478.12 EAU89939.2 - 0.0065 16.3 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SOG2 PF10428.9 EAU89942.1 - 9.2 5.3 19.9 11 5.0 19.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein GMC_oxred_N PF00732.19 EAU89943.2 - 1.9e-48 165.3 0.2 2.1e-47 162.0 0.1 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU89943.2 - 3.9e-31 108.5 0.0 6.3e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DUF5499 PF17603.2 EAU89943.2 - 0.27 11.8 0.3 0.54 10.9 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5499) SUR7 PF06687.12 EAU89944.2 - 8e-13 48.5 1.4 9.3e-13 48.3 1.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 EAU89944.2 - 0.079 12.7 4.4 0.093 12.5 4.4 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Phage_holin_3_6 PF07332.11 EAU89944.2 - 4 7.5 15.5 0.12 12.4 8.7 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Peroxidase_2 PF01328.17 EAU89945.1 - 1.1e-49 169.6 0.0 1.3e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 GATA PF00320.27 EAU89948.1 - 4.5e-07 29.4 7.6 4.5e-07 29.4 7.6 2.0 2 0 0 2 2 2 1 GATA zinc finger zf-C2H2_assoc3 PF16637.5 EAU89950.2 - 0.039 14.1 0.2 0.072 13.3 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz LapA_dom PF06305.11 EAU89950.2 - 0.05 13.4 2.0 0.08 12.8 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3687 PF12459.8 EAU89950.2 - 1.1 8.8 6.2 7.8 6.1 0.5 2.6 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein zf-C2HC5 PF06221.13 EAU89952.2 - 4.1e-18 65.1 5.1 5.9e-18 64.6 5.1 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type LRR_4 PF12799.7 EAU89954.1 - 0.0095 16.3 5.2 0.051 14.0 0.1 3.8 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) RIB43A PF05914.12 EAU89960.2 - 0.0094 14.7 0.1 0.018 13.8 0.1 1.4 1 0 0 1 1 1 1 RIB43A DUF1548 PF07579.11 EAU89960.2 - 0.14 12.5 0.3 0.31 11.4 0.3 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1548) KDZ PF18758.1 EAU89964.1 - 1.1e-56 192.0 0.1 2.2e-56 191.0 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU89964.1 - 3.3e-40 136.6 0.0 9.9e-40 135.0 0.0 1.9 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU89964.1 - 0.00091 19.4 0.6 0.0021 18.2 0.1 1.9 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases FXR_C3 PF16097.5 EAU89964.1 - 0.15 12.8 0.2 0.42 11.3 0.2 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 3 RhoGEF PF00621.20 EAU89965.2 - 5.2e-35 121.3 0.0 7.9e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 EAU89965.2 - 0.0022 18.5 0.0 0.0065 17.0 0.0 1.9 1 1 0 1 1 1 1 PH domain PC-Esterase PF13839.6 EAU89966.1 - 1.1e-05 25.3 6.1 0.0016 18.3 3.2 2.7 3 0 0 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_M28 PF04389.17 EAU89967.1 - 2.8e-38 131.6 0.0 4e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAU89967.1 - 8.1e-13 48.2 3.0 2.3e-12 46.7 1.3 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EAU89967.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ZZ PF00569.17 EAU89970.1 - 0.00055 19.7 12.1 0.00055 19.7 12.1 3.1 3 0 0 3 3 3 1 Zinc finger, ZZ type BSP_II PF05432.11 EAU89970.1 - 0.01 15.5 23.8 0.023 14.4 23.8 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 EAU89970.1 - 0.51 9.7 22.0 0.89 8.9 22.0 1.3 1 0 0 1 1 1 0 SDA1 DUF2201_N PF13203.6 EAU89970.1 - 3 7.4 5.2 3.3 7.2 0.0 2.7 2 1 0 2 2 2 0 Putative metallopeptidase domain RXT2_N PF08595.11 EAU89970.1 - 9 6.3 14.8 8.3 6.4 2.3 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal SAICAR_synt PF01259.18 EAU89971.1 - 2.9e-102 341.6 0.0 3.6e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase PABP PF00658.18 EAU89971.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain MKT1_C PF12246.8 EAU89975.2 - 5e-72 242.0 0.1 7.3e-72 241.5 0.1 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EAU89975.2 - 3.2e-27 94.7 0.0 6.9e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EAU89975.2 - 5.4e-09 36.4 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EAU89975.2 - 4.6e-07 30.1 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region zf-C2H2_jaz PF12171.8 EAU89976.2 - 0.0079 16.5 0.4 0.017 15.4 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EAU89976.2 - 0.058 13.4 0.4 0.17 11.9 0.3 1.8 1 1 1 2 2 2 0 C2H2-type zinc finger DUF3246 PF11596.8 EAU89976.2 - 3.2 7.1 13.8 0.46 9.9 8.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Pirin PF02678.16 EAU89978.1 - 3.8e-26 91.2 1.5 6.5e-26 90.4 1.5 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EAU89978.1 - 4.9e-10 39.0 0.9 1.3e-05 24.8 0.5 2.3 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 EAU89978.1 - 3.1e-05 24.1 0.0 0.00027 21.1 0.0 2.4 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain WD40 PF00400.32 EAU89979.2 - 8.4e-60 197.3 30.9 1.2e-09 38.6 0.2 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU89979.2 - 1.4e-23 83.0 0.5 4.3e-05 23.7 0.0 5.4 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EAU89979.2 - 5e-09 36.5 0.1 9.2e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EAU89979.2 - 7.1e-06 25.0 5.3 0.27 9.8 0.1 4.4 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EAU89979.2 - 0.00035 19.7 0.0 0.17 10.8 0.0 3.4 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EAU89979.2 - 0.02 13.7 0.2 8.9 4.9 0.0 3.5 3 1 1 4 4 4 0 Nup133 N terminal like PD40 PF07676.12 EAU89979.2 - 0.057 13.4 0.1 6.5 6.8 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 EAU89979.2 - 0.22 11.3 0.1 7.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Frtz PF11768.8 EAU89979.2 - 0.24 9.7 0.0 4 5.6 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 EAU89979.2 - 0.24 9.3 0.1 0.41 8.6 0.1 1.2 1 0 0 1 1 1 0 IKI3 family Opi1 PF08618.10 EAU89980.1 - 1.3e-135 452.9 12.0 1.9e-135 452.4 12.0 1.2 1 0 0 1 1 1 1 Transcription factor Opi1 Perilipin PF03036.16 EAU89980.1 - 0.00022 20.4 0.1 0.00053 19.1 0.0 1.7 2 0 0 2 2 2 1 Perilipin family REF PF05755.12 EAU89980.1 - 0.0077 16.1 0.1 0.02 14.7 0.0 1.7 2 0 0 2 2 2 1 Rubber elongation factor protein (REF) Peptidase_C2 PF00648.21 EAU89981.2 - 2e-37 128.8 0.1 4.4e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease zf-C2H2 PF00096.26 EAU89982.2 - 0.00044 20.5 2.0 0.0013 19.1 2.0 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU89982.2 - 0.2 12.6 1.9 0.46 11.4 1.9 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger GATA PF00320.27 EAU89984.2 - 2.2e-16 59.2 3.4 5.3e-16 57.9 3.4 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EAU89984.2 - 0.083 12.4 1.0 0.16 11.5 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding ArfGap PF01412.18 EAU89984.2 - 0.13 12.4 0.2 0.34 11.0 0.2 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf GATA PF00320.27 EAU89985.2 - 1e-12 47.4 2.7 1.9e-12 46.6 2.7 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EAU89985.2 - 0.012 15.1 0.2 0.024 14.1 0.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding NMD3 PF04981.13 EAU89985.2 - 0.014 14.9 0.2 0.016 14.6 0.2 1.1 1 0 0 1 1 1 0 NMD3 family Dioxygenase_C PF00775.21 EAU89986.1 - 5.9e-11 42.1 0.2 8.8e-11 41.6 0.2 1.3 1 0 0 1 1 1 1 Dioxygenase Ribosomal_L37e PF01907.19 EAU89987.1 - 3.4e-26 91.1 12.2 6.1e-26 90.3 12.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EAU89987.1 - 0.007 16.4 1.5 0.01 15.8 1.5 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 EAU89987.1 - 0.012 15.7 0.8 0.013 15.5 0.8 1.3 1 1 0 1 1 1 0 SelR domain HypA PF01155.19 EAU89987.1 - 0.035 14.1 0.7 0.048 13.7 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 EAU89987.1 - 0.28 11.0 3.8 6.5 6.6 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 EAU89987.1 - 0.58 9.7 4.8 0.9 9.1 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon zf-C3HC4_2 PF13923.6 EAU89987.1 - 0.63 9.9 5.3 6.4 6.7 6.4 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Enolase_like_N PF18374.1 EAU89989.2 - 0.18 11.2 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Enolase N-terminal domain-like Peptidase_C2 PF00648.21 EAU89990.2 - 1.1e-61 208.4 0.1 7.7e-61 205.7 0.1 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease GREB1 PF15782.5 EAU89990.2 - 0.19 8.8 8.9 0.29 8.2 8.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Catalase PF00199.19 EAU89992.2 - 9.2e-156 518.8 0.0 1.3e-155 518.3 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EAU89992.2 - 2.1e-12 47.0 0.1 4.1e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ank_2 PF12796.7 EAU89993.2 - 1.5e-37 128.1 3.9 1.3e-10 41.7 0.2 4.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU89993.2 - 1.4e-30 105.0 7.8 3.9e-07 30.2 0.2 6.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU89993.2 - 9.6e-27 90.1 1.9 0.0023 18.3 0.0 8.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EAU89993.2 - 2.2e-25 88.7 3.1 3.5e-09 37.0 0.0 7.1 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU89993.2 - 1.2e-23 82.4 1.0 0.00017 21.9 0.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat DUF4817 PF16087.5 EAU89993.2 - 0.1 12.4 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Ank_2 PF12796.7 EAU89994.2 - 1.2e-49 166.8 11.8 4.6e-14 52.8 0.6 5.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU89994.2 - 8.8e-31 102.5 3.7 6.7e-05 23.0 0.0 9.3 10 0 0 10 10 9 7 Ankyrin repeat Ank_4 PF13637.6 EAU89994.2 - 2.6e-30 104.4 5.4 2.5e-07 31.1 0.0 7.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU89994.2 - 2.7e-30 104.0 10.7 2.7e-07 30.7 0.1 7.5 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU89994.2 - 1.7e-28 97.8 5.7 0.00015 22.1 0.0 9.5 8 1 1 9 9 9 5 Ankyrin repeat NACHT PF05729.12 EAU89994.2 - 1.3e-06 28.4 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EAU89994.2 - 3.2e-06 27.5 0.1 2.2e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU89994.2 - 0.00033 21.1 0.8 0.0017 18.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EAU89994.2 - 0.0016 17.6 0.0 0.0038 16.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.9 EAU89994.2 - 0.017 14.3 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EAU89994.2 - 0.067 13.1 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.6 EAU89994.2 - 0.14 12.4 0.1 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pro-kuma_activ PF09286.11 EAU89995.2 - 2.1e-21 76.7 0.0 7.7e-18 65.2 0.0 3.3 3 0 0 3 3 3 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EAU89995.2 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Subtilase family Ammonium_transp PF00909.21 EAU89998.2 - 1.8e-109 366.1 24.2 2.2e-109 365.8 24.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Methyltransf_25 PF13649.6 EAU89999.2 - 4.4e-13 49.7 0.0 8.2e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU89999.2 - 2e-12 47.6 0.0 3.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU89999.2 - 5.9e-08 32.3 0.0 9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EAU89999.2 - 7.3e-07 29.1 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU89999.2 - 5.5e-05 23.1 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU89999.2 - 0.0003 21.5 0.0 0.00056 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EAU89999.2 - 0.03 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_29 PF03141.16 EAU89999.2 - 0.054 12.1 0.0 0.084 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Phage_integrase PF00589.22 EAU89999.2 - 0.078 12.8 0.4 0.15 11.8 0.4 1.3 1 0 0 1 1 1 0 Phage integrase family MetW PF07021.12 EAU89999.2 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 EAU89999.2 - 0.23 11.6 0.2 0.56 10.3 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Peptidase_M28 PF04389.17 EAU90001.1 - 5.5e-28 98.0 0.0 7.4e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAU90001.1 - 8.6e-09 35.4 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EAU90002.1 - 6.5e-31 107.6 0.0 9.9e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAU90002.1 - 2e-08 34.2 0.0 3.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EAU90002.1 - 0.034 13.2 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase UQ_con PF00179.26 EAU90003.2 - 3.4e-18 65.6 0.0 5.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Thymidylate_kin PF02223.17 EAU90004.2 - 8.7e-35 120.1 0.0 3.5e-34 118.1 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EAU90004.2 - 0.006 16.1 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 EAU90004.2 - 0.097 12.9 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU90004.2 - 0.12 13.0 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EAU90005.1 - 1.2e-37 129.7 34.9 1.2e-37 129.7 34.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily EPL1 PF10513.9 EAU90006.2 - 7.4e-22 78.4 0.1 3.5e-21 76.2 0.0 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like Peptidase_M28 PF04389.17 EAU90007.1 - 2e-39 135.3 0.0 2.9e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAU90007.1 - 6.1e-13 48.6 3.8 1.1e-12 47.8 1.1 2.4 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EAU90007.1 - 0.00024 20.9 0.1 0.00054 19.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EAU90007.1 - 0.034 13.2 0.2 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase DUF2263 PF10021.9 EAU90008.2 - 8.8e-15 55.3 0.0 1.2e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Peptidase_M28 PF04389.17 EAU90009.1 - 1.2e-38 132.9 0.0 1.7e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EAU90009.1 - 1.1e-13 51.0 2.1 5.1e-13 48.9 0.8 2.4 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EAU90009.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EAU90009.1 - 0.16 10.9 0.0 0.36 9.8 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Ank_2 PF12796.7 EAU90010.2 - 1.2e-77 256.5 2.4 2.1e-14 53.9 0.1 8.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90010.2 - 1.6e-55 184.8 5.4 2.4e-09 37.5 0.2 11.6 4 2 8 12 12 12 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU90010.2 - 2e-48 161.8 10.6 1.2e-08 35.0 0.0 11.2 3 2 9 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90010.2 - 2.5e-46 150.3 11.5 0.0063 16.9 0.1 15.3 15 0 0 15 15 15 11 Ankyrin repeat Ank PF00023.30 EAU90010.2 - 3.7e-44 147.3 19.1 0.00027 21.2 0.0 14.2 14 2 0 14 14 13 12 Ankyrin repeat NACHT PF05729.12 EAU90010.2 - 0.0015 18.5 0.0 0.0051 16.7 0.0 2.0 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EAU90010.2 - 0.002 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EAU90010.2 - 0.0085 16.4 0.1 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF3107 PF11305.8 EAU90010.2 - 0.033 14.4 2.6 47 4.3 0.0 5.4 4 2 2 6 6 6 0 Protein of unknown function (DUF3107) DUF2007 PF09413.10 EAU90010.2 - 0.073 13.2 0.0 5.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Putative prokaryotic signal transducing protein DUF2075 PF09848.9 EAU90010.2 - 0.081 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Plavaka PF18759.1 EAU90011.2 - 1.2e-54 185.7 0.0 1.7e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Ish1 PF10281.9 EAU90012.2 - 0.03 14.6 0.2 0.2 12.0 0.1 2.5 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein TMEM247 PF15444.6 EAU90012.2 - 0.22 11.5 5.3 0.36 10.8 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Vma12 PF11712.8 EAU90012.2 - 0.39 10.8 3.2 7 6.7 2.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YabA PF06156.13 EAU90012.2 - 0.67 10.6 5.1 2.7 8.7 5.1 2.0 1 0 0 1 1 1 0 Initiation control protein YabA DUF2570 PF10828.8 EAU90012.2 - 5.3 6.9 9.1 12 5.8 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Ank_2 PF12796.7 EAU90013.1 - 1.4e-93 307.6 12.3 7.6e-15 55.3 0.0 10.3 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.30 EAU90013.1 - 1.6e-67 221.2 16.6 0.00023 21.4 0.0 17.7 17 1 0 17 17 17 15 Ankyrin repeat Ank_4 PF13637.6 EAU90013.1 - 1.6e-59 197.6 11.2 1.3e-09 38.4 0.1 14.5 5 4 11 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU90013.1 - 2.1e-57 190.4 18.2 1.3e-06 28.6 0.0 13.6 6 3 7 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90013.1 - 2.2e-55 178.1 4.8 0.0018 18.6 0.0 18.2 18 0 0 18 18 18 10 Ankyrin repeat AAA_22 PF13401.6 EAU90013.1 - 4.2e-06 27.1 0.5 2.7e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 EAU90013.1 - 0.0017 17.6 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EAU90013.1 - 0.0063 16.4 0.0 0.021 14.7 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU90013.1 - 0.0076 16.6 0.3 0.038 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain VWA_3_C PF18571.1 EAU90013.1 - 0.011 15.5 0.2 8.1 6.4 0.0 5.2 7 0 0 7 7 6 0 von Willebrand factor type A C-terminal domain DUF2075 PF09848.9 EAU90013.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EAU90013.1 - 0.043 14.2 0.0 0.16 12.4 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3881 PF12997.7 EAU90013.1 - 0.11 11.7 0.1 9.2 5.4 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) Arg_repressor PF01316.21 EAU90013.1 - 8 6.3 8.8 21 5.0 0.1 5.0 6 0 0 6 6 6 0 Arginine repressor, DNA binding domain Ank_2 PF12796.7 EAU90015.2 - 1.2e-77 256.5 24.3 2.7e-14 53.5 2.4 8.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90015.2 - 3.1e-62 206.2 20.7 3.1e-09 37.2 0.2 12.5 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90015.2 - 7.7e-48 154.9 17.8 0.06 13.9 0.0 15.8 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.6 EAU90015.2 - 5e-44 147.8 36.1 6.3e-08 32.7 0.7 11.7 5 2 8 13 13 13 12 Ankyrin repeats (many copies) Ank PF00023.30 EAU90015.2 - 1.8e-35 119.8 32.9 0.074 13.5 0.0 15.5 15 0 0 15 15 15 12 Ankyrin repeat AAA_22 PF13401.6 EAU90015.2 - 2.4e-06 27.9 0.0 9.8e-06 25.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90015.2 - 3.9e-06 26.9 0.3 1.3e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 NACHT domain DUF3107 PF11305.8 EAU90015.2 - 8e-06 26.0 18.0 15 5.9 0.1 9.9 4 3 6 11 11 11 0 Protein of unknown function (DUF3107) TPR_20 PF14561.6 EAU90015.2 - 0.00079 19.7 16.2 0.28 11.6 0.0 6.0 5 1 2 7 7 7 2 Tetratricopeptide repeat NB-ARC PF00931.22 EAU90015.2 - 0.0026 17.0 0.0 0.0082 15.4 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EAU90015.2 - 0.0031 17.9 1.5 0.0087 16.5 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain NapD PF03927.13 EAU90015.2 - 0.0083 16.2 0.9 27 4.9 0.1 4.6 3 2 1 4 4 4 0 NapD protein AAA_17 PF13207.6 EAU90015.2 - 0.037 14.5 0.2 5.8 7.3 0.0 3.8 3 1 1 4 4 4 0 AAA domain Mg_chelatase PF01078.21 EAU90015.2 - 0.091 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ldi PF18566.1 EAU90015.2 - 0.16 11.5 6.5 2.6 7.4 0.1 3.7 3 2 0 4 4 4 0 Linalool dehydratase/isomerase DUF3881 PF12997.7 EAU90015.2 - 0.79 8.9 4.9 21 4.2 0.2 3.7 2 1 2 4 4 4 0 Domain of unknown function, E. rectale Gene description (DUF3881) CTNNBL PF08216.11 EAU90015.2 - 1 9.6 11.5 13 6.0 0.2 5.8 7 0 0 7 7 7 0 Catenin-beta-like, Arm-motif containing nuclear Ank_2 PF12796.7 EAU90016.2 - 2.8e-37 127.2 5.2 2.2e-11 44.2 0.2 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU90016.2 - 9.8e-25 83.9 5.0 0.0018 18.6 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EAU90016.2 - 6e-24 84.1 8.5 2.2e-05 24.9 0.1 7.7 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU90016.2 - 1.6e-23 82.4 11.2 4.7e-07 30.0 0.1 6.4 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EAU90016.2 - 3.6e-23 80.9 7.5 0.0069 16.8 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat AAA_22 PF13401.6 EAU90016.2 - 6.3e-06 26.5 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90016.2 - 0.00043 20.2 0.3 0.0039 17.1 0.1 2.6 2 0 0 2 2 2 1 NACHT domain SMI1_KNR4 PF09346.10 EAU90016.2 - 0.15 12.4 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Pro_isomerase PF00160.21 EAU90017.2 - 7.6e-39 133.5 4.7 1.2e-38 132.9 0.0 3.0 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EAU90017.2 - 0.054 13.9 0.0 0.054 13.9 0.0 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4604) UQ_con PF00179.26 EAU90018.2 - 4.7e-18 65.2 0.0 5.3e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EAU90018.2 - 0.0029 17.9 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain VHS PF00790.19 EAU90019.1 - 1.9e-30 105.6 0.1 3.6e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EAU90019.1 - 4.8e-14 51.7 0.0 8.6e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAU90019.1 - 5e-14 51.7 0.1 9.1e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EAU90019.1 - 7.9e-14 51.7 2.9 3.1e-13 49.8 1.6 2.2 2 0 0 2 2 2 1 GAT domain SH3_9 PF14604.6 EAU90019.1 - 1.2e-13 50.7 0.1 2.3e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.20 EAU90019.1 - 0.0033 17.2 1.3 0.0033 17.2 1.3 2.1 2 0 0 2 2 2 1 Ubiquitin interaction motif IKBKB_SDD PF18397.1 EAU90019.1 - 0.098 11.9 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 IQBAL scaffold dimerization domain DUF445 PF04286.12 EAU90019.1 - 0.25 11.1 2.8 1.4 8.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) SBF PF01758.16 EAU90020.2 - 0.014 15.1 3.4 0.17 11.6 1.1 2.3 2 0 0 2 2 2 0 Sodium Bile acid symporter family OSTMP1 PF09777.9 EAU90020.2 - 0.36 10.2 1.0 8.6 5.7 0.4 2.4 2 0 0 2 2 2 0 Osteopetrosis-associated transmembrane protein 1 precursor Ank_2 PF12796.7 EAU90021.1 - 5.8e-62 206.3 41.8 2.7e-13 50.3 1.6 6.8 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU90021.1 - 4.8e-36 122.3 25.6 7.3e-08 32.5 0.6 9.4 6 3 2 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAU90021.1 - 2.9e-33 112.8 29.6 0.00013 22.3 0.2 11.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_3 PF13606.6 EAU90021.1 - 3.9e-32 106.7 16.7 0.00016 21.8 0.0 11.4 11 0 0 11 11 11 8 Ankyrin repeat Ank_4 PF13637.6 EAU90021.1 - 1e-30 105.7 16.2 1.7e-06 28.4 0.1 10.5 6 2 6 12 12 12 7 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU90021.1 - 6.9e-07 29.6 0.2 3.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU90021.1 - 0.00063 19.7 0.3 0.0023 17.8 0.1 2.1 2 0 0 2 2 2 1 NACHT domain DUF3107 PF11305.8 EAU90021.1 - 0.1 12.9 0.2 4.9 7.5 0.0 3.7 2 1 3 5 5 5 0 Protein of unknown function (DUF3107) NB-ARC PF00931.22 EAU90021.1 - 0.13 11.4 0.0 0.51 9.5 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain Exo_endo_phos PF03372.23 EAU90023.1 - 3.6e-13 49.6 0.0 8.4e-13 48.4 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EAU90023.1 - 7.2e-06 26.0 2.3 7.2e-06 26.0 2.3 1.8 2 0 0 2 2 2 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 EAU90023.1 - 0.004 17.0 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Macoilin PF09726.9 EAU90023.1 - 0.95 7.9 7.9 1.3 7.5 7.9 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_C2 PF00648.21 EAU90024.2 - 4.5e-58 196.6 2.3 3.7e-57 193.6 0.7 2.5 2 1 0 2 2 2 1 Calpain family cysteine protease Mito_fiss_reg PF05308.11 EAU90024.2 - 4.9 7.2 5.8 8 6.5 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DAP3 PF10236.9 EAU90026.1 - 1.6e-61 208.2 0.0 2.2e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EAU90026.1 - 3.4e-08 34.0 0.0 6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EAU90026.1 - 9.4e-05 22.4 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EAU90026.1 - 0.0037 17.0 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_30 PF13604.6 EAU90026.1 - 0.006 16.3 0.0 0.0096 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90026.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF1810 PF08837.11 EAU90026.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) AAA_10 PF12846.7 EAU90026.1 - 0.094 11.6 0.1 1.7 7.5 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain Bac_DnaA PF00308.18 EAU90026.1 - 0.096 12.5 0.0 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein CPSF100_C PF13299.6 EAU90026.1 - 0.1 12.8 0.4 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2045 PF09741.9 EAU90026.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) NB-ARC PF00931.22 EAU90026.1 - 0.15 11.2 0.0 0.42 9.8 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF2791 PF10923.8 EAU90026.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_25 PF13481.6 EAU90026.1 - 0.17 11.4 0.1 0.59 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EAU90027.2 - 1.2e-45 154.0 12.6 7.8e-12 45.6 0.4 5.5 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU90027.2 - 1.2e-30 102.2 3.6 0.0036 17.7 0.0 9.9 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 EAU90027.2 - 7.5e-27 92.6 15.6 0.002 18.5 0.1 9.7 10 0 0 10 10 9 7 Ankyrin repeat Ank_4 PF13637.6 EAU90027.2 - 1.8e-26 92.1 11.9 2.1e-05 24.9 0.0 8.9 3 2 7 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU90027.2 - 7.8e-24 83.4 20.6 0.00021 21.5 0.2 8.6 3 2 5 8 8 8 7 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU90027.2 - 4.4e-07 30.3 0.0 1.5e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90027.2 - 2.4e-05 24.3 0.2 8.7e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 NACHT domain Ldi PF18566.1 EAU90027.2 - 0.0011 18.5 1.4 6.9 6.1 0.1 4.0 2 1 0 3 3 3 2 Linalool dehydratase/isomerase NB-ARC PF00931.22 EAU90027.2 - 0.0056 15.9 0.0 0.014 14.6 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain Mg_chelatase PF01078.21 EAU90027.2 - 0.048 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF1949 PF09186.11 EAU90027.2 - 0.054 13.4 0.3 88 3.1 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1949) Nitro_FeMo-Co PF02579.17 EAU90027.2 - 0.073 13.4 0.9 86 3.6 0.0 4.4 2 1 4 6 6 6 0 Dinitrogenase iron-molybdenum cofactor Pro_isomerase PF00160.21 EAU90030.2 - 1.1e-16 61.4 0.0 2.8e-14 53.7 0.0 2.2 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_2 PF12796.7 EAU90032.2 - 2.2e-27 95.4 3.4 4.7e-11 43.1 0.7 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU90032.2 - 5.8e-19 67.9 3.5 0.00021 21.5 0.0 6.2 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90032.2 - 2.2e-18 64.4 0.0 0.06 13.9 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EAU90032.2 - 2.9e-17 62.2 4.2 0.03 14.8 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EAU90032.2 - 3.4e-14 53.0 2.2 1.1e-05 25.9 0.0 5.5 3 1 2 6 6 6 3 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU90032.2 - 6.8e-07 29.6 0.0 2.6e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90032.2 - 2.3e-05 24.4 0.1 5.7e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EAU90032.2 - 0.0057 15.9 0.0 0.016 14.4 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain Mg_chelatase PF01078.21 EAU90032.2 - 0.034 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T3SS_ExsE PF18286.1 EAU90032.2 - 0.11 12.4 1.2 71 3.4 0.1 3.9 3 0 0 3 3 3 0 Type III secretion system ExsE Ank_2 PF12796.7 EAU90033.2 - 9.9e-42 141.4 13.2 1.6e-13 51.0 0.3 5.2 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90033.2 - 1e-30 105.7 9.2 1.3e-05 25.6 0.1 7.9 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90033.2 - 1.6e-23 80.2 1.3 0.001 19.3 0.0 8.4 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 EAU90033.2 - 2e-21 75.4 13.4 0.0025 18.2 0.1 9.2 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAU90033.2 - 4.3e-19 68.3 17.3 0.0029 17.9 0.1 7.5 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Nitro_FeMo-Co PF02579.17 EAU90033.2 - 1.5e-05 25.2 0.9 0.85 10.0 0.0 5.3 4 2 3 7 7 7 1 Dinitrogenase iron-molybdenum cofactor Ldi PF18566.1 EAU90033.2 - 0.0096 15.4 4.0 0.18 11.2 0.2 3.5 1 1 3 4 4 4 1 Linalool dehydratase/isomerase Sacchrp_dh_NADP PF03435.18 EAU90033.2 - 0.015 15.6 0.0 12 6.1 0.0 4.2 3 2 3 6 6 6 0 Saccharopine dehydrogenase NADP binding domain DUF1949 PF09186.11 EAU90033.2 - 0.25 11.3 0.8 15 5.5 0.0 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1949) VWA_3_C PF18571.1 EAU90033.2 - 1.7 8.6 11.8 14 5.6 0.0 5.6 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain DAP3 PF10236.9 EAU90034.2 - 3.9e-05 23.0 0.0 9.9e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Ank_2 PF12796.7 EAU90036.2 - 2.8e-59 197.6 4.2 1.5e-11 44.7 0.0 5.7 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90036.2 - 2.5e-28 98.1 2.6 2e-08 34.6 0.0 7.4 2 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 EAU90036.2 - 5.7e-27 92.9 0.6 0.026 15.0 0.0 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAU90036.2 - 5.2e-22 77.6 7.9 1.5e-06 28.3 0.0 6.5 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90036.2 - 3.9e-21 72.9 2.5 0.014 15.8 0.0 8.3 9 0 0 9 9 7 4 Ankyrin repeat AAA_22 PF13401.6 EAU90036.2 - 7e-07 29.6 0.0 2.8e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90036.2 - 1.2e-05 25.2 0.1 3e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU90036.2 - 0.0025 18.2 0.0 0.0098 16.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EAU90036.2 - 0.0071 15.9 0.0 0.059 12.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF4951 PF16309.5 EAU90036.2 - 0.0089 16.0 0.7 13 5.9 0.0 4.0 3 1 1 4 4 4 1 Domian of unknown function (DUF4951) NB-ARC PF00931.22 EAU90036.2 - 0.011 14.9 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EAU90036.2 - 0.037 13.2 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3107 PF11305.8 EAU90036.2 - 0.13 12.5 2.8 54 4.1 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF3107) Ank_2 PF12796.7 EAU90037.2 - 1.8e-91 300.8 26.4 1.1e-15 57.9 0.0 9.6 2 1 9 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90037.2 - 1.5e-60 200.8 2.9 2.3e-08 34.4 0.0 13.3 7 3 7 14 14 14 12 Ankyrin repeats (many copies) Ank PF00023.30 EAU90037.2 - 1.2e-57 190.0 13.3 0.00024 21.4 0.0 15.1 15 0 0 15 15 15 13 Ankyrin repeat Ank_5 PF13857.6 EAU90037.2 - 3.4e-52 173.8 12.8 6.8e-07 29.5 0.0 12.1 5 4 5 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90037.2 - 3.7e-50 162.1 7.7 0.0072 16.7 0.0 16.5 16 0 0 16 16 16 10 Ankyrin repeat AAA_22 PF13401.6 EAU90037.2 - 4.3e-06 27.0 0.0 3.4e-05 24.1 0.0 2.4 1 1 0 2 2 2 1 AAA domain NapD PF03927.13 EAU90037.2 - 8.3e-06 25.8 0.3 1.2 9.2 0.1 4.9 3 1 1 4 4 4 2 NapD protein AAA_16 PF13191.6 EAU90037.2 - 0.016 15.6 0.0 0.057 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EAU90037.2 - 0.032 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EAU90037.2 - 0.038 13.2 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EAU90037.2 - 0.064 13.7 0.0 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAU90037.2 - 0.098 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain F-box-like PF12937.7 EAU90039.1 - 0.00029 20.7 0.0 0.00095 19.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90039.1 - 0.08 12.9 0.9 0.53 10.2 0.2 2.9 2 1 0 2 2 2 0 F-box domain TPR_2 PF07719.17 EAU90043.1 - 2.6e-10 39.6 4.6 0.017 15.2 0.0 3.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAU90043.1 - 3.2e-06 27.3 1.7 0.066 13.5 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90043.1 - 1.9e-05 24.3 4.2 0.75 9.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU90043.1 - 0.00011 21.8 5.0 0.088 12.5 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 EAU90043.1 - 0.00016 21.6 0.8 1.3 9.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAU90043.1 - 0.00024 20.9 4.6 0.00075 19.3 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90043.1 - 0.00065 20.3 3.1 1.1 10.2 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU90043.1 - 0.006 16.8 1.6 0.05 13.8 0.2 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EAU90043.1 - 0.0074 16.8 4.9 0.43 11.1 0.5 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU90043.1 - 0.016 15.9 7.0 0.93 10.2 1.2 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAU90043.1 - 0.045 13.8 1.1 11 6.2 0.3 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DEAD PF00270.29 EAU90044.1 - 2.6e-47 160.9 0.0 4.4e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU90044.1 - 3.7e-30 104.5 0.0 1.3e-29 102.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU90044.1 - 0.082 12.9 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 EAU90044.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EAU90044.1 - 0.28 10.4 0.0 0.44 9.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Spt20 PF12090.8 EAU90045.1 - 1.8e-28 99.7 0.6 1.3e-14 54.4 0.1 10.9 2 2 3 5 5 5 2 Spt20 family DNA_binding_1 PF01035.20 EAU90046.2 - 4.4e-26 90.8 0.0 5.5e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Ank_2 PF12796.7 EAU90048.1 - 2e-12 47.5 0.4 1.5e-06 28.7 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU90048.1 - 6.3e-12 45.5 3.1 1.7e-09 37.8 0.9 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU90048.1 - 3.4e-10 40.3 2.0 0.0013 19.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90048.1 - 1.5e-09 37.3 0.4 1.2e-05 25.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EAU90048.1 - 8.1e-07 29.2 2.8 1.8e-05 25.0 0.2 3.1 4 0 0 4 4 4 1 Ankyrin repeat Chromo_shadow PF01393.19 EAU90049.2 - 6.4e-17 61.4 0.1 1.6e-15 56.9 0.0 2.5 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 EAU90049.2 - 5e-11 42.3 0.1 1.5e-10 40.8 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4917 PF16263.5 EAU90049.2 - 0.054 12.8 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) MRC1 PF09444.10 EAU90049.2 - 0.65 10.5 18.6 3.5 8.1 16.2 2.1 1 1 1 2 2 2 0 MRC1-like domain RRM_1 PF00076.22 EAU90050.2 - 6.7e-16 57.9 0.0 1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAU90050.2 - 0.0038 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 EAU90050.2 - 0.022 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EAU90050.2 - 0.05 13.5 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 RL domain zf-MYND PF01753.18 EAU90051.2 - 4.3e-08 33.1 14.6 8.1e-08 32.2 14.6 1.5 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.7 EAU90051.2 - 0.0057 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) Tmpp129 PF10272.9 EAU90051.2 - 0.22 10.8 4.5 0.28 10.4 4.5 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-Mss51 PF13824.6 EAU90051.2 - 8.6 6.5 11.9 6.4 7.0 9.9 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Coprogen_oxidas PF01218.18 EAU90055.1 - 2.2e-134 446.8 0.0 2.5e-134 446.6 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glutaredoxin PF00462.24 EAU90056.1 - 1.8e-17 63.3 0.0 4.4e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin CxC4 PF18717.1 EAU90057.2 - 6.6e-39 132.7 0.5 1.4e-38 131.6 0.1 1.8 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases YcbB PF08664.10 EAU90058.1 - 0.15 12.1 0.7 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 YcbB domain GFA PF04828.14 EAU90059.1 - 5.2e-19 68.4 0.1 6.8e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 EAU90060.1 - 4.2e-28 98.3 49.7 4.2e-28 98.3 40.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPMT PF05724.11 EAU90061.1 - 5.7e-35 120.9 0.0 6.7e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 EAU90061.1 - 2.7e-13 50.0 0.0 3.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU90061.1 - 6.6e-13 49.2 0.0 1e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU90061.1 - 2.9e-10 40.6 0.0 4.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU90061.1 - 3.2e-09 37.4 0.0 5.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU90061.1 - 6.3e-08 32.6 0.0 9.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAU90061.1 - 4.7e-05 22.9 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EAU90061.1 - 0.016 15.2 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 EAU90061.1 - 0.023 14.7 0.0 0.041 13.9 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase MTS PF05175.14 EAU90061.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 EAU90061.1 - 0.04 13.2 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.18 EAU90061.1 - 0.08 12.4 0.2 3.9 6.9 0.0 2.7 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain PCMT PF01135.19 EAU90061.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EAU90061.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FMO-like PF00743.19 EAU90062.2 - 3.9e-20 71.8 0.0 4e-13 48.7 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAU90062.2 - 2.2e-16 60.0 0.2 8.7e-13 48.2 0.7 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU90062.2 - 2.8e-12 46.5 0.0 1.3e-08 34.5 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAU90062.2 - 2.2e-08 33.7 0.1 1.2e-06 28.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EAU90062.2 - 3.4e-05 24.0 0.2 0.00011 22.4 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.19 EAU90062.2 - 6.7e-05 22.3 0.1 0.00021 20.7 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EAU90062.2 - 0.0035 16.7 0.2 0.006 15.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAU90062.2 - 0.0049 16.2 0.2 0.096 11.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EAU90062.2 - 0.0063 17.1 0.1 0.34 11.5 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU90062.2 - 0.0071 15.4 0.2 0.077 12.0 0.1 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 EAU90062.2 - 0.012 15.2 0.0 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAU90062.2 - 0.043 13.8 0.6 16 5.5 0.1 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EAU90062.2 - 0.049 12.7 0.3 0.1 11.7 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EAU90062.2 - 0.1 11.6 0.4 1.1 8.2 0.5 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EAU90062.2 - 0.19 10.4 0.4 0.51 9.0 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 EAU90063.2 - 6.3e-07 28.9 0.1 0.0011 18.3 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU90063.2 - 6.1e-06 25.7 0.0 3.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU90063.2 - 4e-05 23.7 0.0 9.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EAU90063.2 - 0.00015 21.2 0.0 0.00023 20.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 EAU90063.2 - 0.00074 18.1 0.0 0.17 10.2 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 EAU90063.2 - 0.0033 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EAU90063.2 - 0.0034 16.5 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EAU90063.2 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EAU90063.2 - 0.017 15.7 0.1 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU90063.2 - 0.023 13.4 0.0 0.071 11.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 EAU90063.2 - 0.026 14.1 0.2 3.4 7.1 0.1 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EAU90063.2 - 0.04 13.9 0.0 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EAU90063.2 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family V-ATPase_C PF03223.15 EAU90063.2 - 0.1 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 V-ATPase subunit C Amino_oxidase PF01593.24 EAU90063.2 - 0.12 11.6 0.0 8.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 EAU90063.2 - 0.15 12.3 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Mis12 PF05859.12 EAU90068.2 - 0.048 13.7 0.0 3.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Mis12 protein Gly_transf_sug PF04488.15 EAU90070.2 - 3.3e-07 30.8 0.0 5.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EAU90070.2 - 0.0073 15.7 0.3 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein zf-DNL PF05180.12 EAU90071.2 - 1.5e-27 95.3 0.9 1.9e-27 95.0 0.9 1.1 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 EAU90071.2 - 0.039 13.8 1.9 0.073 12.9 1.9 1.4 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) YCII PF03795.14 EAU90071.2 - 0.11 13.0 0.1 0.15 12.5 0.1 1.3 1 1 0 1 1 1 0 YCII-related domain Bunya_NS-S PF01104.17 EAU90072.2 - 0.22 11.3 0.9 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s Adaptin_N PF01602.20 EAU90073.2 - 1.3e-10 40.4 2.5 0.0021 16.7 0.0 3.8 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 EAU90073.2 - 1.2e-09 38.4 5.5 0.38 11.2 0.1 6.6 7 0 0 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 EAU90073.2 - 1e-06 29.1 8.0 0.0017 18.8 0.2 7.0 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.22 EAU90073.2 - 7.7e-06 25.7 17.0 0.1 12.9 0.1 10.0 13 0 0 13 13 13 2 HEAT repeat Arm PF00514.23 EAU90073.2 - 0.00012 21.9 1.5 0.0023 17.9 0.2 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat PTS_2-RNA PF01885.16 EAU90074.2 - 1.9e-40 138.8 0.0 2.4e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family MAGSP PF03082.14 EAU90074.2 - 0.12 12.0 0.0 6.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Male accessory gland secretory protein RTC4 PF14474.6 EAU90075.2 - 5.1e-26 91.2 0.0 1.2e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain Flavin_Reduct PF01613.18 EAU90076.2 - 4.8e-27 94.9 0.1 9.5e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 Flavin reductase like domain RabGAP-TBC PF00566.18 EAU90080.2 - 2.2e-44 151.7 0.0 3.3e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 EAU90080.2 - 0.00011 22.6 0.2 0.00044 20.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EAU90080.2 - 0.00017 20.9 0.1 0.00061 19.2 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EAU90080.2 - 0.00018 21.2 0.2 0.00075 19.2 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EAU90080.2 - 0.042 13.7 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair GRAM PF02893.20 EAU90080.2 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 GRAM domain SPARC_Ca_bdg PF10591.9 EAU90080.2 - 0.065 13.6 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EAU90080.2 - 0.072 12.6 0.0 0.27 10.8 0.0 2.0 1 0 0 1 1 1 0 EF hand WD40 PF00400.32 EAU90081.2 - 2.9e-43 145.0 18.2 1.2e-07 32.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU90081.2 - 1.3e-17 63.9 5.4 0.00084 19.6 0.0 5.1 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAU90081.2 - 4.3e-07 29.0 6.6 0.0067 15.1 0.4 4.4 2 1 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EAU90081.2 - 1.7e-06 28.1 0.2 0.0029 17.5 0.1 3.4 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EAU90081.2 - 7.5e-06 25.5 0.1 0.024 14.0 0.0 2.5 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EAU90081.2 - 0.0002 20.5 1.7 2.8 6.8 0.0 3.9 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EAU90081.2 - 0.004 16.1 5.3 0.2 10.6 0.2 3.8 1 1 3 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Pectate_lyase22 PF14583.6 EAU90081.2 - 0.0087 14.8 0.0 0.021 13.5 0.0 1.6 1 0 0 1 1 1 1 Oligogalacturonate lyase CAP_N PF01213.19 EAU90081.2 - 3.5 7.0 6.8 5.2 6.5 6.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TEA PF01285.18 EAU90082.2 - 1.5e-22 79.4 0.1 2.7e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Tmemb_170 PF10190.9 EAU90083.2 - 9.4e-06 25.9 2.5 0.00096 19.5 0.6 2.2 2 0 0 2 2 2 2 Putative transmembrane protein 170 DUF4131 PF13567.6 EAU90083.2 - 5.6 6.6 8.5 10 5.7 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MMR_HSR1 PF01926.23 EAU90084.2 - 8.7e-17 61.3 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU90084.2 - 7.2e-06 26.2 0.0 0.00011 22.3 0.0 2.1 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 EAU90084.2 - 0.00047 19.6 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EAU90084.2 - 0.0019 18.1 0.0 0.035 14.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EAU90084.2 - 0.0028 17.2 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 EAU90084.2 - 0.013 14.8 0.0 1 8.5 0.0 2.2 1 1 0 2 2 2 0 Septin AAA_29 PF13555.6 EAU90084.2 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EAU90084.2 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EAU90084.2 - 0.2 11.2 0.1 2.3 7.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Peptidase_M43 PF05572.13 EAU90085.2 - 7.8e-16 58.4 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU90085.2 - 1.4e-05 25.3 0.0 5.2e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAU90085.2 - 0.00027 20.7 0.3 0.00068 19.3 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EAU90085.2 - 0.00033 21.2 0.0 0.001 19.6 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU90085.2 - 0.015 15.2 0.2 0.023 14.5 0.2 1.4 1 1 0 1 1 1 0 Matrixin WT1 PF02165.15 EAU90085.2 - 0.08 12.2 0.3 0.12 11.6 0.3 1.2 1 0 0 1 1 1 0 Wilm's tumour protein Reprolysin_2 PF13574.6 EAU90085.2 - 0.12 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EAU90085.2 - 0.24 11.0 0.7 0.5 9.9 0.5 1.6 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF383 PF04063.14 EAU90089.1 - 3.3e-61 206.3 0.0 1.2e-60 204.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EAU90089.1 - 3.6e-20 71.6 1.6 8.9e-20 70.3 1.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Hydrophobin PF01185.18 EAU90090.1 - 3.8e-25 88.3 5.7 5e-25 87.9 5.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin R_equi_Vir PF05526.11 EAU90090.1 - 0.019 14.9 0.6 0.025 14.5 0.4 1.3 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein p450 PF00067.22 EAU90091.1 - 2.2e-78 264.1 0.0 2.7e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AICARFT_IMPCHas PF01808.18 EAU90092.1 - 1.3e-89 300.6 0.0 1.7e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EAU90092.1 - 4.1e-23 81.4 0.0 7.4e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.6 EAU90093.2 - 8e-40 136.5 0.1 1.1e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EAU90093.2 - 3.8e-10 39.8 0.0 5e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EAU90093.2 - 6.2e-06 26.5 0.1 1e-05 25.7 0.1 1.4 1 0 0 1 1 1 1 HD domain PX PF00787.24 EAU90095.1 - 2.3e-23 82.3 0.0 9.1e-23 80.4 0.0 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EAU90095.1 - 1.2e-05 24.9 7.0 0.017 14.7 0.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like DUF4391 PF14335.6 EAU90095.1 - 0.006 16.3 0.8 0.013 15.3 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) BAR PF03114.18 EAU90095.1 - 0.015 14.9 1.5 0.015 14.9 1.5 2.1 2 0 0 2 2 2 0 BAR domain FapA PF03961.13 EAU90095.1 - 0.3 9.7 0.6 0.57 8.7 0.6 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5339 PF17274.2 EAU90095.1 - 3.1 8.7 5.7 1.4 9.9 2.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5339) ETX_MTX2 PF03318.13 EAU90096.2 - 4.4e-09 36.5 7.9 5.9e-09 36.0 7.9 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 EAU90096.2 - 6.2e-05 22.4 1.5 8.2e-05 22.0 1.5 1.1 1 0 0 1 1 1 1 Aerolysin toxin Ank_2 PF12796.7 EAU90097.2 - 2.4e-30 105.0 11.3 2.6e-11 43.9 0.2 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAU90097.2 - 5.9e-17 61.3 6.9 0.0025 18.2 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EAU90097.2 - 4.1e-16 58.8 5.5 9.9e-09 35.3 0.1 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU90097.2 - 3.3e-15 56.2 5.5 1.2e-06 29.0 0.1 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90097.2 - 9.1e-14 50.2 4.9 0.43 11.3 0.0 6.7 7 0 0 7 7 7 4 Ankyrin repeat FliT PF05400.13 EAU90097.2 - 0.35 11.7 1.3 1.1 10.1 0.3 2.3 2 0 0 2 2 2 0 Flagellar protein FliT O-FucT PF10250.9 EAU90099.2 - 0.0027 17.5 0.1 1.5 8.5 0.0 2.8 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Pkinase_fungal PF17667.1 EAU90103.2 - 2.1e-33 115.7 0.1 2.1e-22 79.5 0.0 2.1 1 1 0 2 2 2 2 Fungal protein kinase CE2_N PF17996.1 EAU90104.2 - 1.4e-05 25.1 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal N36 PF11438.8 EAU90104.2 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) DUF805 PF05656.14 EAU90104.2 - 0.11 12.9 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) VPDSG-CTERM PF18205.1 EAU90104.2 - 9.3 6.2 9.1 1.2 9.0 4.6 1.9 2 0 0 2 2 2 0 VPDSG-CTERM motif PBECR5 PF18814.1 EAU90107.1 - 0.015 15.3 0.3 0.03 14.3 0.3 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 Glyco_hydro_115 PF15979.5 EAU90107.1 - 0.05 13.0 2.0 0.082 12.3 2.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 Spc7 PF08317.11 EAU90107.1 - 0.076 11.9 0.0 0.076 11.9 0.0 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein OmpH PF03938.14 EAU90107.1 - 5.4 7.4 6.9 4.7 7.5 3.6 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Velvet PF11754.8 EAU90108.2 - 1.4e-20 74.4 0.0 1.6e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Velvet factor LRR_4 PF12799.7 EAU90109.1 - 0.032 14.7 5.2 0.14 12.6 0.3 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Smr PF01713.21 EAU90111.1 - 6.3e-12 45.7 0.0 1.7e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 EAU90111.1 - 1.7e-07 31.5 4.4 4.7e-06 26.9 4.3 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Acetyltransf_10 PF13673.7 EAU90111.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2015 PF09435.10 EAU90112.1 - 1.4e-36 124.7 0.0 1.7e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Sds3 PF08598.11 EAU90114.2 - 1.2e-05 25.4 4.8 1.2e-05 25.4 4.8 1.5 1 1 0 1 1 1 1 Sds3-like DLH PF01738.18 EAU90115.1 - 5.2e-15 55.6 0.0 2.6e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Glyco_hydro_72 PF03198.14 EAU90116.1 - 2.6e-97 325.9 0.2 4.1e-97 325.2 0.0 1.3 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.13 EAU90116.1 - 2.7e-19 69.6 0.5 7e-19 68.3 0.5 1.7 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EAU90116.1 - 5.6e-05 22.7 0.1 0.00026 20.5 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EAU90116.1 - 0.021 13.9 0.0 0.053 12.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF2183 PF09949.9 EAU90117.2 - 9.4e-26 90.1 0.0 1.7e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EAU90117.2 - 0.00026 20.6 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) p450 PF00067.22 EAU90118.2 - 2.2e-55 188.2 0.0 3.3e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4381 PF14316.6 EAU90118.2 - 0.011 15.9 0.4 0.022 15.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GATA PF00320.27 EAU90119.2 - 4.5e-14 51.8 2.4 4.5e-14 51.8 2.4 2.0 2 0 0 2 2 2 1 GATA zinc finger ArfGap PF01412.18 EAU90119.2 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf SnoaL_2 PF12680.7 EAU90122.1 - 0.00012 22.6 0.0 0.00021 21.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Clathrin PF00637.20 EAU90123.2 - 4.3e-207 678.3 31.9 3.4e-33 114.5 0.5 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EAU90123.2 - 1.1e-37 126.6 1.6 5.5e-07 29.6 0.1 7.0 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EAU90123.2 - 2.1e-31 107.6 0.1 1.5e-30 104.9 0.1 2.6 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 EAU90123.2 - 1e-11 44.0 3.3 1.7e-11 43.2 0.1 2.9 3 0 0 3 3 3 1 Clathrin, heavy-chain linker TPR_14 PF13428.6 EAU90123.2 - 0.0033 18.1 16.5 0.17 12.8 0.3 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat Vps39_1 PF10366.9 EAU90123.2 - 0.02 15.2 11.2 2.2 8.6 0.0 6.6 7 0 0 7 7 7 0 Vacuolar sorting protein 39 domain 1 Coatomer_WDAD PF04053.14 EAU90123.2 - 0.041 12.9 11.0 0.13 11.2 0.1 3.9 4 0 0 4 4 4 0 Coatomer WD associated region TPR_1 PF00515.28 EAU90123.2 - 0.16 11.9 4.2 13 5.8 0.1 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU90123.2 - 0.37 10.9 8.3 31 4.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90123.2 - 2.2 8.7 5.8 7.9 7.0 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat PQ-loop PF04193.14 EAU90124.2 - 4.2e-20 71.3 5.1 9.7e-15 54.1 0.8 3.3 3 0 0 3 3 3 2 PQ loop repeat UAA PF08449.11 EAU90125.2 - 1.7e-09 37.3 10.6 1.7e-09 37.3 10.6 1.7 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 EAU90125.2 - 5.9e-07 29.7 18.8 7.2e-06 26.2 6.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family CPSase_L_D2 PF02786.17 EAU90126.2 - 1.9e-80 269.4 0.2 3.2e-80 268.6 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EAU90126.2 - 6.2e-69 231.7 0.0 1.1e-68 230.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 EAU90126.2 - 1.1e-31 110.4 0.0 2.5e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.19 EAU90126.2 - 6.8e-31 106.6 0.1 2.7e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EAU90126.2 - 3.1e-21 76.0 0.2 1.1e-20 74.3 0.2 1.9 1 1 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EAU90126.2 - 7.3e-19 67.4 6.4 1.6e-18 66.3 4.4 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EAU90126.2 - 1.2e-11 44.2 7.1 2.2e-05 24.2 0.3 2.9 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EAU90126.2 - 1.9e-10 40.6 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EAU90126.2 - 6.1e-08 32.4 0.1 1.3e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EAU90126.2 - 9.1e-08 32.8 1.3 0.0024 18.5 0.2 3.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 EAU90126.2 - 4.8e-06 26.0 0.8 0.0035 16.6 0.1 2.6 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 EAU90126.2 - 9.4e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EAU90126.2 - 0.00027 20.6 0.0 0.0006 19.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 EAU90126.2 - 0.00052 19.9 2.9 0.0034 17.3 0.5 3.3 3 1 0 3 3 3 1 Glycine cleavage H-protein NQRA PF05896.11 EAU90126.2 - 0.0028 17.1 0.5 0.0066 15.9 0.5 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_ST PF14397.6 EAU90126.2 - 0.0042 16.4 0.0 0.0095 15.2 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 EAU90126.2 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RnfC_N PF13375.6 EAU90126.2 - 0.0071 16.3 2.2 0.028 14.4 1.9 2.2 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 EAU90126.2 - 0.029 14.3 0.4 0.26 11.3 0.4 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M23 PF01551.22 EAU90126.2 - 0.031 14.5 0.6 0.46 10.7 0.6 3.0 1 1 0 1 1 1 0 Peptidase family M23 PTS_EIIA_1 PF00358.20 EAU90126.2 - 0.074 12.8 0.3 2 8.2 0.1 2.6 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NMO PF03060.15 EAU90127.2 - 7.1e-33 114.4 3.8 4.6e-23 82.1 0.1 2.7 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EAU90127.2 - 0.00099 18.2 1.6 0.0062 15.6 1.2 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EAU90127.2 - 0.027 13.5 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain LSM PF01423.22 EAU90128.1 - 1.6e-16 59.7 0.0 2.2e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain PLATZ PF04640.14 EAU90129.1 - 0.073 13.7 1.4 0.16 12.6 1.4 1.5 1 0 0 1 1 1 0 PLATZ transcription factor Opiods_neuropep PF01160.18 EAU90129.1 - 0.17 12.0 2.2 0.4 10.8 2.2 1.5 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide SHR3_chaperone PF08229.11 EAU90130.1 - 5.5e-45 152.6 0.2 6.1e-45 152.5 0.2 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 LapA_dom PF06305.11 EAU90130.1 - 2.6 7.9 7.8 0.48 10.3 0.5 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RhoGAP PF00620.27 EAU90131.2 - 1.5e-42 145.0 0.0 2.3e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EAU90131.2 - 1.3e-15 57.8 0.0 3.2e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 EAU90131.2 - 1.5e-08 34.6 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 EAU90131.2 - 8.1e-06 26.2 0.0 1.7e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EAU90131.2 - 0.0078 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGAP PF00620.27 EAU90142.2 - 6.1e-31 107.3 0.0 1.4e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EAU90142.2 - 2.3e-25 88.6 34.9 4.8e-10 39.5 8.2 4.4 4 0 0 4 4 4 4 LIM domain ParA PF10609.9 EAU90143.1 - 9e-96 320.1 0.0 1.1e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EAU90143.1 - 8.1e-09 35.6 0.0 3e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EAU90143.1 - 0.00013 22.0 0.1 0.0011 18.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EAU90143.1 - 0.00013 21.3 0.8 0.002 17.4 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EAU90143.1 - 0.0024 17.4 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EAU90143.1 - 0.0088 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EAU90143.1 - 0.019 14.4 0.0 1.6 8.1 0.0 2.5 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 EAU90143.1 - 0.033 14.1 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 EAU90143.1 - 0.1 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.11 EAU90143.1 - 0.17 11.6 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 Virulence-associated protein E Ras PF00071.22 EAU90144.2 - 5.8e-52 175.6 0.0 7.5e-52 175.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU90144.2 - 5.2e-21 75.1 0.0 7.3e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU90144.2 - 2.3e-08 33.7 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAU90144.2 - 0.0025 17.7 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EAU90144.2 - 0.0028 17.1 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EAU90144.2 - 0.0042 16.5 0.0 0.0054 16.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EAU90144.2 - 0.009 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Skp1_POZ PF03931.15 EAU90144.2 - 0.11 12.7 0.3 0.25 11.5 0.1 1.6 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain AAA_16 PF13191.6 EAU90144.2 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.18 EAU90145.2 - 2.9e-17 62.6 0.3 7e-17 61.3 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATG16 PF08614.11 EAU90146.2 - 0.00081 19.7 19.4 0.032 14.5 13.4 2.6 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 EAU90146.2 - 0.0051 16.0 9.5 0.0051 16.0 9.5 2.1 2 0 0 2 2 2 1 HAP1 N-terminal conserved region Spc7 PF08317.11 EAU90146.2 - 0.011 14.7 17.9 0.25 10.2 7.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Takusan PF04822.13 EAU90146.2 - 0.02 14.8 8.2 0.16 11.9 0.5 3.1 2 2 0 2 2 2 0 Takusan FH2 PF02181.23 EAU90146.2 - 0.031 13.4 0.1 0.031 13.4 0.1 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain Atg14 PF10186.9 EAU90146.2 - 0.13 11.3 9.9 3 6.8 6.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec8_exocyst PF04048.14 EAU90146.2 - 0.36 10.7 6.7 3.6 7.5 0.2 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.12 EAU90146.2 - 0.44 10.6 20.6 1.3 9.1 4.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EAU90146.2 - 0.62 9.4 18.0 0.4 10.0 1.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding T3SSipB PF16535.5 EAU90146.2 - 0.78 10.2 8.3 2.4 8.6 2.8 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF724 PF05266.14 EAU90146.2 - 0.8 9.5 14.9 0.45 10.3 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF5339 PF17274.2 EAU90146.2 - 0.89 10.5 4.4 26 5.8 1.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF1664 PF07889.12 EAU90146.2 - 1.3 9.1 7.3 6.7 6.8 2.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EAU90146.2 - 1.3 9.6 22.9 1 9.9 3.5 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Rx_N PF18052.1 EAU90146.2 - 1.5 9.1 10.1 0.66 10.3 0.5 2.5 2 0 0 2 2 2 0 Rx N-terminal domain DUF5636 PF18686.1 EAU90146.2 - 1.8 8.7 4.6 0.48 10.6 0.8 1.9 2 1 1 3 3 2 0 Family of unknown function (DUF5636) DUF4201 PF13870.6 EAU90146.2 - 1.8 8.2 16.8 2.3 7.9 7.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Laminin_II PF06009.12 EAU90146.2 - 2.3 8.3 8.6 5.8 6.9 3.5 2.3 2 0 0 2 2 2 0 Laminin Domain II Fez1 PF06818.15 EAU90146.2 - 2.3 8.6 14.9 6.1 7.2 0.4 2.2 2 0 0 2 2 2 0 Fez1 Phlebovirus_NSM PF07246.11 EAU90146.2 - 2.8 7.2 6.3 9.8 5.5 0.1 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Fib_alpha PF08702.10 EAU90146.2 - 3 8.0 10.3 4.2 7.5 4.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SOGA PF11365.8 EAU90146.2 - 3.9 8.7 14.7 13 7.0 8.1 2.5 2 0 0 2 2 2 0 Protein SOGA Metal_resist PF13801.6 EAU90146.2 - 8.3 6.6 12.9 3.9 7.7 4.0 3.2 2 1 1 3 3 3 0 Heavy-metal resistance DUF4140 PF13600.6 EAU90146.2 - 8.4 6.9 14.3 0.72 10.3 0.1 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) HIP1_clath_bdg PF16515.5 EAU90146.2 - 9.1 7.0 21.5 0.13 12.8 1.5 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PRKG1_interact PF15898.5 EAU90146.2 - 9.2 7.2 18.4 4.4 8.3 0.7 2.6 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain MscL PF01741.18 EAU90147.2 - 5.5e-18 65.4 0.0 7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 EAU90147.2 - 0.017 15.1 0.0 0.025 14.6 0.0 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-BED PF02892.15 EAU90147.2 - 0.025 14.6 1.2 0.062 13.3 1.2 1.7 1 1 0 1 1 1 0 BED zinc finger PSI_PsaH PF03244.14 EAU90147.2 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI zinc_ribbon_2 PF13240.6 EAU90147.2 - 0.11 12.3 1.0 0.18 11.6 1.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 EAU90147.2 - 0.16 12.1 1.3 0.24 11.5 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C3HC4_3 PF13920.6 EAU90147.2 - 0.42 10.5 4.2 0.88 9.5 4.2 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1771 PF08590.10 EAU90148.1 - 8.9e-16 58.0 8.9 1.7e-15 57.1 8.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 EAU90148.1 - 2e-08 34.0 8.2 2.3e-06 27.5 1.2 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EAU90148.1 - 7.6e-07 28.9 6.5 8.4e-05 22.4 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAU90148.1 - 1.4e-06 29.0 3.4 3.3e-05 24.5 0.1 2.4 1 1 1 2 2 2 1 Torus domain Smr PF01713.21 EAU90148.1 - 9.2e-05 22.7 0.1 0.00022 21.5 0.1 1.6 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 EAU90148.1 - 0.00018 21.9 5.9 0.13 12.7 0.8 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 EAU90148.1 - 0.0012 18.5 3.4 0.031 14.0 0.4 2.5 2 0 0 2 2 2 1 Putative zinc-finger domain DUF5471 PF17565.2 EAU90148.1 - 0.023 15.0 0.5 0.061 13.6 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5471) zf-CCCH_4 PF18044.1 EAU90148.1 - 0.039 13.8 12.8 1.7 8.5 0.9 3.2 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EAU90148.1 - 0.058 13.6 3.9 0.38 11.0 3.9 2.0 1 1 0 1 1 1 0 Zinc-finger containing family zf-CDGSH PF09360.10 EAU90149.2 - 0.0034 17.5 0.6 2.8 8.2 0.1 2.5 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type bVLRF1 PF18826.1 EAU90151.1 - 4.6e-67 224.5 0.0 8.3e-67 223.7 0.0 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_3 PF13606.6 EAU90151.1 - 0.0077 16.7 0.0 0.021 15.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EAU90151.1 - 0.025 15.2 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAU90151.1 - 0.028 15.0 0.0 0.067 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU90151.1 - 0.035 14.4 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 EAU90151.1 - 0.046 14.2 0.0 0.09 13.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat PMM PF03332.13 EAU90152.1 - 2.2e-106 354.6 0.4 2.5e-106 354.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EAU90152.1 - 5.7e-05 23.0 0.0 0.00073 19.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU90152.1 - 0.064 13.5 0.1 0.085 13.1 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 EAU90152.1 - 0.073 13.5 0.2 3.6 8.0 0.0 2.5 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase FliX PF10768.9 EAU90152.1 - 0.12 12.9 0.1 0.19 12.2 0.1 1.2 1 0 0 1 1 1 0 Class II flagellar assembly regulator PMM PF03332.13 EAU90153.2 - 4.6e-12 46.2 0.0 5.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DNA_pol_B PF00136.21 EAU90154.1 - 1.1e-146 489.2 0.0 1.5e-146 488.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EAU90154.1 - 1.1e-75 254.9 0.0 1.9e-75 254.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EAU90154.1 - 1.7e-17 63.7 9.1 3.6e-17 62.6 9.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EAU90154.1 - 0.0013 17.7 0.1 0.0025 16.7 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 EAU90154.1 - 0.0036 17.0 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EAU90154.1 - 0.0085 16.1 0.1 0.044 13.8 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_A_exo1 PF01612.20 EAU90154.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease C1_1 PF00130.22 EAU90154.1 - 1.1 9.2 10.9 63 3.6 10.9 2.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SET PF00856.28 EAU90155.1 - 3.8e-08 33.9 0.0 4.2e-06 27.3 0.0 2.2 1 1 2 3 3 3 2 SET domain DUF1965 PF09248.10 EAU90155.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1965) Ribosomal_L7Ae PF01248.26 EAU90156.1 - 5.9e-22 77.2 0.0 6.8e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SQHop_cyclase_N PF13249.6 EAU90157.2 - 7.9e-48 163.0 1.6 5.7e-39 134.0 0.2 4.1 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EAU90157.2 - 9.9e-48 162.9 5.5 6.7e-44 150.3 1.7 2.4 2 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EAU90157.2 - 1.4e-34 117.5 3.9 9.8e-11 41.2 0.2 6.7 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EAU90157.2 - 0.00054 19.1 0.0 0.47 9.4 0.0 3.6 1 1 2 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 EAU90157.2 - 0.021 14.1 2.5 16 4.7 0.0 4.5 4 1 2 6 6 6 0 Pectic acid lyase Brix PF04427.18 EAU90158.2 - 5.8e-35 121.1 0.0 8.4e-33 114.1 0.0 2.2 1 1 0 1 1 1 1 Brix domain Actin PF00022.19 EAU90160.1 - 1.5e-40 139.1 0.0 2.3e-39 135.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EAU90160.1 - 0.00024 20.0 0.0 0.0007 18.5 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein Cnd2 PF05786.14 EAU90161.1 - 5.8e-171 570.9 13.7 2.3e-170 568.9 13.7 1.7 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EAU90161.1 - 0.0027 17.9 0.0 0.024 14.8 0.0 2.4 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF3450 PF11932.8 EAU90162.2 - 0.33 10.2 11.3 0.09 12.1 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fungal_trans_2 PF11951.8 EAU90162.2 - 0.47 9.2 4.0 0.68 8.7 3.4 1.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain CLZ PF16526.5 EAU90162.2 - 2 8.8 5.3 3 8.3 0.8 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EAU90162.2 - 2.8 8.0 5.5 3.9 7.5 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2333 PF10095.9 EAU90162.2 - 2.9 6.8 5.1 0.28 10.2 0.8 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) SKA1 PF07160.12 EAU90162.2 - 3.2 7.5 10.7 1.5 8.6 4.7 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Methyltransf_16 PF10294.9 EAU90163.2 - 1.5e-26 93.2 0.1 4.9e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EAU90163.2 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran_2 PF16949.5 EAU90163.2 - 0.15 10.9 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Putative ATP-binding cassette FPN1 PF06963.12 EAU90164.2 - 9.2e-77 258.4 14.0 3.3e-53 180.8 5.9 3.0 1 1 2 3 3 3 3 Ferroportin1 (FPN1) DEAD PF00270.29 EAU90170.1 - 2.9e-40 137.9 0.1 4.3e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU90170.1 - 5.4e-29 100.8 0.0 3.9e-28 98.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDC45 PF02724.14 EAU90170.1 - 0.00024 19.5 1.2 0.00031 19.2 1.2 1.1 1 0 0 1 1 1 1 CDC45-like protein ResIII PF04851.15 EAU90170.1 - 0.00039 20.5 0.0 0.00096 19.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWIRM-assoc_2 PF16496.5 EAU90170.1 - 0.00071 18.6 5.5 0.001 18.0 5.5 1.1 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal Apt1 PF10351.9 EAU90170.1 - 0.055 12.3 2.3 0.41 9.5 2.8 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Merozoite_SPAM PF07133.11 EAU90170.1 - 0.4 10.7 12.0 0.74 9.8 12.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Presenilin PF01080.17 EAU90170.1 - 0.92 8.2 3.6 1.3 7.7 3.6 1.1 1 0 0 1 1 1 0 Presenilin RNA_polI_A34 PF08208.11 EAU90170.1 - 3.1 7.8 18.3 5.5 7.0 18.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Spt5_N PF11942.8 EAU90170.1 - 5.6 8.0 14.5 18 6.4 14.5 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Peptidase_M20 PF01546.28 EAU90172.2 - 2.2e-27 96.1 0.0 1.6e-26 93.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAU90172.2 - 3e-14 52.9 0.0 4.8e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase dimerisation domain PepSY_like PF11396.8 EAU90172.2 - 0.076 13.6 0.0 0.59 10.7 0.0 2.1 1 1 1 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like DRMBL PF07522.14 EAU90173.1 - 1.6e-31 108.7 0.0 3e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EAU90173.1 - 2.1e-06 27.4 0.0 4.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EAU90173.1 - 0.02 14.9 0.7 0.055 13.5 0.7 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Ribosomal_S4e PF00900.20 EAU90174.2 - 1.4e-36 124.3 0.1 4.7e-36 122.5 0.1 1.9 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EAU90174.2 - 4.4e-26 90.3 0.1 8.8e-26 89.3 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EAU90174.2 - 1.1e-20 73.5 4.5 4e-20 71.6 5.0 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 EAU90174.2 - 5.5e-09 35.6 0.1 1.2e-08 34.5 0.0 1.6 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EAU90174.2 - 2.6e-06 27.2 4.0 8.4e-06 25.6 4.0 1.9 1 0 0 1 1 1 1 KOW motif ComC PF03047.14 EAU90174.2 - 0.038 13.8 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 COMC family Sipho_tail PF05709.11 EAU90174.2 - 0.096 12.1 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Phage tail protein TPT PF03151.16 EAU90175.2 - 1.8e-54 185.1 16.6 2.2e-54 184.8 16.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAU90175.2 - 5.6e-12 46.0 29.6 6.6e-07 29.6 14.0 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EAU90175.2 - 3.3e-08 33.1 16.8 4.5e-08 32.6 16.8 1.2 1 0 0 1 1 1 1 UAA transporter family Multi_Drug_Res PF00893.19 EAU90175.2 - 3.2 8.5 11.1 2.1 9.1 0.8 3.5 2 1 1 3 3 3 0 Small Multidrug Resistance protein CRAL_TRIO PF00650.20 EAU90176.2 - 2.7e-26 92.2 0.0 4.2e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAU90176.2 - 0.00098 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Paf1 PF03985.13 EAU90178.2 - 5.3e-68 230.0 0.7 6.5e-68 229.7 0.7 1.0 1 0 0 1 1 1 1 Paf1 Tail_tube PF10618.9 EAU90178.2 - 0.16 11.8 0.1 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 Phage tail tube protein SnoaL_2 PF12680.7 EAU90180.1 - 1.2e-06 29.1 0.0 1.6e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EAU90180.1 - 0.00017 21.4 0.1 0.00027 20.8 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase NTF2 PF02136.20 EAU90180.1 - 0.0034 17.9 0.0 0.0045 17.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain AAA_3 PF07726.11 EAU90180.1 - 0.036 13.9 0.0 0.09 12.6 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Aminotran_5 PF00266.19 EAU90181.2 - 6.2e-22 78.0 0.0 3.8e-21 75.5 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V AATF-Che1 PF13339.6 EAU90182.2 - 2.3e-29 102.8 2.9 2.3e-29 102.8 2.9 2.6 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 EAU90182.2 - 1.1e-28 99.5 0.6 3.3e-28 98.0 0.0 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal BOP1NT PF08145.12 EAU90182.2 - 0.029 14.3 0.8 0.029 14.3 0.8 1.6 2 0 0 2 2 2 0 BOP1NT (NUC169) domain Lin-8 PF03353.15 EAU90182.2 - 0.18 11.3 6.2 0.31 10.6 6.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DNA_pol_B PF00136.21 EAU90184.2 - 2.2e-114 382.7 0.0 3e-114 382.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EAU90184.2 - 1.9e-62 210.3 0.9 3.2e-62 209.6 0.9 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EAU90184.2 - 1.3e-29 103.4 0.0 3.8e-28 98.6 0.0 2.8 2 1 1 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EAU90184.2 - 1.1e-19 70.3 5.1 4.3e-19 68.4 5.1 2.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EAU90184.2 - 0.035 13.0 0.0 0.08 11.8 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Pirin PF02678.16 EAU90185.1 - 1.7e-25 89.1 0.8 2.8e-25 88.4 0.8 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EAU90185.1 - 2.2e-09 36.9 0.8 5.4e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 EAU90185.1 - 1.3e-08 34.9 0.1 4.8e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_3 PF05899.12 EAU90185.1 - 0.038 13.7 0.3 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF4470 PF14737.6 EAU90186.1 - 8.8e-19 67.5 0.0 1.5e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Metallothio_Euk PF12749.7 EAU90187.1 - 0.0004 20.5 38.4 0.00047 20.3 38.4 1.1 1 0 0 1 1 1 1 Eukaryotic metallothionein MFS_1 PF07690.16 EAU90189.2 - 2.2e-32 112.4 41.9 3.8e-30 105.0 33.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EAU90190.2 - 1.1e-32 113.3 24.2 1.5e-32 112.9 24.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU90190.2 - 8.4e-07 28.2 6.8 8.4e-07 28.2 6.8 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EAU90190.2 - 0.0024 17.2 2.4 0.0024 17.2 2.4 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF996 PF06195.13 EAU90190.2 - 0.38 11.0 8.5 0.29 11.4 2.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF996) F-box PF00646.33 EAU90193.1 - 2.4e-05 24.1 1.2 6.5e-05 22.7 1.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU90193.1 - 5e-05 23.1 0.9 0.00015 21.6 0.9 1.9 1 0 0 1 1 1 1 F-box-like Hydrophobin PF01185.18 EAU90194.1 - 7.4e-23 81.0 6.7 9.5e-23 80.6 6.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.12 EAU90194.1 - 1.9 9.3 8.3 5 7.9 0.7 2.8 3 0 0 3 3 3 0 Ion channel inhibitory toxin TPR_11 PF13414.6 EAU90198.1 - 4.9e-16 58.1 6.5 7.2e-09 35.2 0.8 4.6 3 2 2 5 5 5 4 TPR repeat TPR_2 PF07719.17 EAU90198.1 - 2.7e-13 48.9 5.3 3.7e-07 29.8 0.1 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90198.1 - 3.5e-13 48.8 2.7 4.3e-08 32.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAU90198.1 - 2.6e-11 43.8 2.3 7.5e-05 23.2 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU90198.1 - 3.8e-11 43.5 3.9 2.6e-06 28.0 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAU90198.1 - 1.9e-09 37.7 5.5 1.8e-05 25.0 0.4 3.5 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAU90198.1 - 2.1e-09 37.1 0.1 0.021 15.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90198.1 - 4.7e-08 32.6 3.8 0.00088 19.3 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EAU90198.1 - 7.2e-07 28.7 0.4 1.1e-06 28.1 0.4 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90198.1 - 1.1e-06 29.0 5.0 0.0072 17.0 0.0 4.4 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU90198.1 - 1.3e-05 24.8 2.8 0.099 12.7 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAU90198.1 - 1.3e-05 24.9 3.3 0.013 15.3 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EAU90198.1 - 2.5e-05 24.6 2.1 0.018 15.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU90198.1 - 0.00014 22.0 0.5 0.0078 16.4 0.3 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EAU90198.1 - 0.00015 21.9 0.2 0.14 12.3 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 EAU90198.1 - 0.00026 21.0 6.8 0.62 10.2 0.1 3.3 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EAU90198.1 - 0.0065 16.4 3.3 1.1 9.3 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EAU90198.1 - 0.0067 16.7 0.8 0.44 10.9 0.1 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EAU90198.1 - 0.014 15.4 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 EAU90198.1 - 0.021 14.9 0.7 0.87 9.6 0.1 2.6 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) PCDO_beta_N PF12391.8 EAU90198.1 - 0.035 13.7 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal TPR_4 PF07721.14 EAU90198.1 - 0.039 14.6 4.1 2.2 9.2 0.1 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF4175 PF13779.6 EAU90198.1 - 0.063 11.2 0.0 0.088 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tim17 PF02466.19 EAU90199.1 - 2.2e-25 89.2 6.7 2.9e-25 88.8 6.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Hydrophobin PF01185.18 EAU90201.1 - 8.3e-24 84.0 5.5 1.2e-23 83.6 5.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Y_phosphatase2 PF03162.13 EAU90202.1 - 0.08 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Mus7 PF09462.10 EAU90203.1 - 1.8e-30 106.4 0.1 1.5e-26 93.4 0.2 2.2 2 0 0 2 2 2 2 Mus7/MMS22 family SR-25 PF10500.9 EAU90203.1 - 0.00054 19.6 10.8 0.00054 19.6 10.8 3.8 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein MMS22L_N PF14910.6 EAU90203.1 - 0.001 17.6 0.1 0.0017 16.9 0.1 1.2 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, N-terminal PIEZO PF15917.5 EAU90203.1 - 0.99 8.8 4.0 3.2 7.2 4.0 1.8 1 0 0 1 1 1 0 Piezo NDUF_B5 PF09781.9 EAU90203.1 - 8.7 5.9 6.5 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Cytochrom_C1 PF02167.15 EAU90205.1 - 7.4e-98 326.6 0.0 9.1e-98 326.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EAU90205.1 - 0.0017 18.6 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EAU90205.1 - 0.01 17.0 0.2 0.034 15.3 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.16 EAU90206.1 - 6.9e-24 84.7 5.6 2.2e-22 79.8 5.6 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EAU90206.1 - 1.8e-06 28.0 0.2 5.2e-06 26.5 0.2 1.8 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EF-hand_2 PF09068.11 EAU90206.1 - 0.097 12.8 0.3 3.3 7.9 0.1 2.6 2 0 0 2 2 2 0 EF hand tRNA_int_endo PF01974.17 EAU90207.2 - 1.7e-18 66.4 2.4 3.4e-17 62.3 2.4 2.3 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EAU90207.2 - 0.0016 18.1 0.0 0.11 12.1 0.0 2.6 2 1 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain WD40 PF00400.32 EAU90208.2 - 2e-09 37.9 14.8 0.11 13.5 2.0 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat HAND PF09110.11 EAU90208.2 - 0.022 15.5 7.0 0.022 15.5 7.0 1.9 2 0 0 2 2 2 0 HAND Dynein_IC2 PF11540.8 EAU90208.2 - 0.2 11.6 0.9 0.44 10.6 0.2 2.1 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 KAR9 PF08580.10 EAU90209.1 - 0.03 12.9 1.2 0.036 12.6 1.2 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Rhomboid PF01694.22 EAU90212.2 - 3.4e-19 69.3 15.9 3.4e-18 66.1 15.9 2.4 1 1 0 1 1 1 1 Rhomboid family zf-C3HC4 PF00097.25 EAU90213.2 - 1.7e-08 34.2 5.3 3.7e-08 33.1 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU90213.2 - 2.4e-08 33.7 3.9 4.6e-08 32.8 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 EAU90213.2 - 4.7e-08 32.6 15.8 6.1e-05 22.7 6.4 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EAU90213.2 - 1.5e-06 28.8 1.2 0.00014 22.5 0.2 2.6 2 0 0 2 2 2 1 Torus domain zf-RING_5 PF14634.6 EAU90213.2 - 8.4e-06 25.7 4.9 8.4e-06 25.7 4.9 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-CCCH PF00642.24 EAU90213.2 - 1.4e-05 24.9 12.6 0.00021 21.1 3.0 2.6 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 EAU90213.2 - 1.8e-05 25.0 5.7 1.8e-05 25.0 5.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf_CCCH_4 PF18345.1 EAU90213.2 - 8.1e-05 22.5 10.2 8.1e-05 22.5 10.2 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-RING_UBOX PF13445.6 EAU90213.2 - 0.00011 22.1 3.4 0.00012 22.0 1.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EAU90213.2 - 0.00032 20.9 2.0 0.00084 19.6 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EAU90213.2 - 0.0013 18.5 2.3 0.0013 18.5 2.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU90213.2 - 0.069 13.3 6.9 0.42 10.8 6.9 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING BUD22 PF09073.10 EAU90213.2 - 0.082 12.2 5.6 0.15 11.4 5.6 1.5 1 0 0 1 1 1 0 BUD22 zf-CCCH_2 PF14608.6 EAU90213.2 - 0.095 13.2 20.3 1.6 9.3 4.5 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Prok-RING_4 PF14447.6 EAU90213.2 - 0.53 10.2 9.2 0.18 11.7 5.2 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EAU90213.2 - 0.76 9.7 6.4 4 7.4 6.4 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EAU90213.2 - 1.1 9.4 5.3 0.21 11.6 1.1 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Methyltransf_16 PF10294.9 EAU90214.2 - 8.1e-26 90.8 0.0 1.3e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EAU90214.2 - 7.5e-06 25.9 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU90214.2 - 0.017 15.8 0.0 0.044 14.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EAU90214.2 - 0.029 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EAU90214.2 - 0.05 13.0 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EAU90214.2 - 0.11 13.3 0.0 0.26 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EAU90214.2 - 0.19 10.8 0.0 0.36 9.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Histone PF00125.24 EAU90215.2 - 1.2e-06 28.9 0.0 1.7e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Asp PF00026.23 EAU90216.2 - 5.3e-65 219.9 0.7 2.5e-58 198.0 0.2 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU90216.2 - 1.4e-10 41.7 1.1 5.7e-10 39.7 1.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Histone PF00125.24 EAU90217.1 - 1.4e-49 167.8 3.8 1.6e-49 167.6 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EAU90217.1 - 2.7e-05 24.4 0.1 4.2e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAU90217.1 - 5.9e-05 23.2 0.1 0.0001 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAU90217.1 - 0.00043 20.9 2.3 0.00055 20.5 2.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EAU90217.1 - 0.00071 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EAU90217.1 - 0.091 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 EAU90218.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAU90218.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EAU90218.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EAU90218.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU90218.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAU90218.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF98 PF01947.16 EAU90219.2 - 0.17 11.8 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase SIR2 PF02146.17 EAU90220.2 - 3.4e-43 147.6 0.0 2.5e-32 112.2 0.0 2.3 1 1 1 2 2 2 2 Sir2 family DUF592 PF04574.13 EAU90220.2 - 1.9e-05 24.5 0.5 0.00025 20.9 0.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EAU90220.2 - 0.028 14.1 0.1 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain RNA_pol_Rpb2_2 PF04561.14 EAU90220.2 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 PTS_2-RNA PF01885.16 EAU90221.2 - 2.1e-10 40.9 0.0 2.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Arginosuc_synth PF00764.19 EAU90222.1 - 2.4e-153 511.0 0.0 2.9e-153 510.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EAU90222.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EAU90222.1 - 0.014 14.2 0.0 0.028 13.2 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase zf-C3HC4_3 PF13920.6 EAU90223.2 - 5.9e-07 29.3 10.0 4.5e-06 26.4 10.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU90223.2 - 3.9e-06 26.6 6.9 7.9e-06 25.7 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU90223.2 - 5.6e-06 26.2 6.4 1.1e-05 25.3 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAU90223.2 - 1.3e-05 25.0 1.6 1.3e-05 25.0 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU90223.2 - 8.2e-05 22.5 8.1 0.00018 21.5 8.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAU90223.2 - 0.00033 20.9 13.0 0.0045 17.3 13.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EAU90223.2 - 0.00041 20.4 1.5 0.00041 20.4 1.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EAU90223.2 - 0.00042 20.1 1.5 0.00042 20.1 1.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 CENP-F_leu_zip PF10473.9 EAU90223.2 - 0.0053 16.8 2.6 0.0089 16.1 2.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CC2-LZ PF16516.5 EAU90223.2 - 0.016 15.6 3.2 0.03 14.7 3.2 1.4 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HAUS-augmin3 PF14932.6 EAU90223.2 - 0.029 14.0 1.2 0.049 13.2 1.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Gln-synt_C PF00120.24 EAU90223.2 - 0.029 13.4 0.2 0.059 12.4 0.1 1.5 2 0 0 2 2 2 0 Glutamine synthetase, catalytic domain BST2 PF16716.5 EAU90223.2 - 0.035 14.7 1.8 0.068 13.8 1.8 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 EAU90223.2 - 0.041 13.9 1.1 0.072 13.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Zn_ribbon_17 PF17120.5 EAU90223.2 - 0.063 12.9 0.4 0.063 12.9 0.4 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Sec8_exocyst PF04048.14 EAU90223.2 - 0.067 13.1 1.4 0.12 12.2 1.4 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.10 EAU90223.2 - 0.078 13.2 1.7 0.14 12.3 1.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tmpp129 PF10272.9 EAU90223.2 - 0.14 11.5 4.8 0.22 10.8 4.8 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Spc7 PF08317.11 EAU90223.2 - 0.14 11.0 6.0 0.2 10.5 6.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-rbx1 PF12678.7 EAU90223.2 - 0.21 11.9 7.7 0.9 9.9 7.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain TMPIT PF07851.13 EAU90223.2 - 0.29 10.3 2.5 0.45 9.7 2.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Sipho_Gp157 PF05565.11 EAU90223.2 - 0.31 11.0 2.3 0.55 10.2 2.3 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 COG2 PF06148.11 EAU90223.2 - 0.34 11.0 2.2 0.6 10.2 2.2 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 EAU90223.2 - 0.37 10.1 3.6 0.55 9.5 3.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-RING_6 PF14835.6 EAU90223.2 - 1.6 8.7 5.0 0.28 11.1 0.4 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Nucleopor_Nup85 PF07575.13 EAU90224.2 - 1.6e-55 188.7 0.0 2.4e-36 125.5 0.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin GGDEF PF00990.21 EAU90224.2 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain RhoGAP PF00620.27 EAU90225.2 - 2e-47 160.8 0.1 4.4e-47 159.7 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EAU90225.2 - 2.6e-15 56.5 0.5 9.3e-15 54.7 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PCRF PF03462.18 EAU90225.2 - 0.0029 17.5 1.4 0.0065 16.4 1.4 1.5 1 0 0 1 1 1 1 PCRF domain DUF5344 PF17279.2 EAU90225.2 - 0.0069 16.9 1.4 5.2 7.7 0.1 3.5 2 1 1 3 3 3 2 Family of unknown function (DUF5344) DUF4461 PF14688.6 EAU90225.2 - 0.0075 16.1 3.0 0.055 13.2 1.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4461) ERM PF00769.19 EAU90225.2 - 0.012 15.4 5.5 0.019 14.8 5.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ALMT PF11744.8 EAU90225.2 - 0.035 12.9 0.5 0.049 12.5 0.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1664 PF07889.12 EAU90225.2 - 0.094 12.8 0.7 1.5 8.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EAU90225.2 - 0.11 12.6 7.5 0.28 11.2 7.5 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 EAU90225.2 - 0.11 12.2 3.7 0.06 13.1 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 EAU90225.2 - 0.15 12.2 2.1 0.54 10.4 2.1 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 EAU90225.2 - 0.17 11.4 1.7 0.37 10.3 1.7 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit TBCA PF02970.16 EAU90225.2 - 0.17 12.2 5.0 0.76 10.1 4.9 2.1 1 1 0 1 1 1 0 Tubulin binding cofactor A SKA2 PF16740.5 EAU90225.2 - 0.3 10.9 5.4 0.36 10.6 3.7 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 EAU90225.2 - 0.59 9.9 8.3 0.067 13.0 2.3 2.5 3 0 0 3 3 3 0 Septum formation initiator F-box-like PF12937.7 EAU90226.2 - 8.4e-06 25.6 0.3 2.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like Adeno_hexon PF01065.19 EAU90226.2 - 0.3 9.9 0.0 0.4 9.5 0.0 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain CENP-T_C PF15511.6 EAU90227.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EAU90227.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EAU90227.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EAU90227.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EAU90227.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EAU90227.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EAU90228.1 - 1.4e-49 167.8 3.8 1.6e-49 167.6 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EAU90228.1 - 2.7e-05 24.4 0.1 4.2e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAU90228.1 - 5.9e-05 23.2 0.1 0.0001 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAU90228.1 - 0.00043 20.9 2.3 0.00055 20.5 2.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EAU90228.1 - 0.00071 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EAU90228.1 - 0.091 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated FA_hydroxylase PF04116.13 EAU90231.1 - 3.2e-22 79.3 13.1 3.2e-22 79.3 13.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HTH_psq PF05225.16 EAU90231.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Rcd1 PF04078.13 EAU90232.1 - 4.3e-125 416.2 3.8 4.9e-125 416.0 3.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like NIR_SIR PF01077.22 EAU90233.1 - 1.4e-51 174.1 0.0 8.4e-48 161.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EAU90233.1 - 1e-30 105.4 0.0 4.4e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EAU90233.1 - 7.8e-29 100.7 0.0 1.4e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EAU90233.1 - 0.048 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.7 EAU90233.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain DUF1295 PF06966.12 EAU90234.1 - 3.6e-52 177.2 2.4 5.2e-52 176.7 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EAU90234.1 - 0.002 18.5 1.4 0.0066 16.8 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EAU90234.1 - 0.016 15.2 2.6 0.087 12.8 0.0 2.9 3 0 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EAU90234.1 - 0.016 15.6 4.3 0.021 15.2 0.0 2.9 3 0 0 3 3 3 0 Phospholipid methyltransferase DUF4746 PF15928.5 EAU90235.2 - 0.0011 18.4 0.4 0.0011 18.4 0.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4746) PH PF00169.29 EAU90235.2 - 0.012 16.2 0.2 0.036 14.6 0.2 1.9 1 0 0 1 1 1 0 PH domain TFIIA PF03153.13 EAU90235.2 - 0.097 12.7 12.1 0.13 12.2 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GMC_oxred_C PF05199.13 EAU90238.1 - 1e-16 61.8 0.0 1.9e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Nup214_FG PF18617.1 EAU90238.1 - 5 7.7 5.0 24 5.5 0.0 2.8 3 0 0 3 3 3 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain Symplekin_C PF12295.8 EAU90241.2 - 5.5e-31 108.1 1.1 1.5e-30 106.7 0.1 2.2 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EAU90241.2 - 4.7e-29 101.7 3.7 1.8e-13 50.7 0.1 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF3453) SnoaL_2 PF12680.7 EAU90242.1 - 0.0026 18.4 0.0 0.0036 17.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Ribosomal_S19 PF00203.21 EAU90244.2 - 1.3e-33 114.7 0.2 2e-33 114.1 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 EAU90244.2 - 0.021 14.9 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Flagellar assembly protein FliH Ribosomal_60s PF00428.19 EAU90245.2 - 7.9e-27 93.7 8.8 1.1e-26 93.3 8.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EAU90245.2 - 0.033 14.5 1.1 0.037 14.4 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain Paramyxo_C PF01692.18 EAU90245.2 - 0.076 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C DUF3824 PF12868.7 EAU90245.2 - 0.16 12.6 3.0 0.24 12.1 3.0 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cytomega_UL84 PF06284.11 EAU90245.2 - 1 7.8 2.5 1.3 7.4 2.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Fungal_trans PF04082.18 EAU90246.2 - 3.9e-20 72.0 0.5 6.3e-20 71.3 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU90246.2 - 2.7e-09 37.0 10.3 2.7e-09 37.0 10.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-ATPase_G PF03179.15 EAU90247.1 - 3e-35 120.9 12.0 3.4e-35 120.7 12.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EAU90247.1 - 0.094 12.8 16.4 0.04 14.0 13.7 1.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 EAU90247.1 - 1.2 9.6 14.7 2.5 8.6 14.7 1.6 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SnoaL_2 PF12680.7 EAU90250.1 - 0.068 13.8 0.4 0.097 13.3 0.4 1.4 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 EAU90252.2 - 0.0018 18.9 0.0 0.0036 17.9 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EAU90252.2 - 0.013 16.0 0.0 0.018 15.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Transposase_21 PF02992.14 EAU90253.2 - 2.7e-06 26.8 0.0 5.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 EAU90253.2 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Vfa1 PF08432.10 EAU90255.2 - 0.078 13.3 0.2 0.078 13.3 0.2 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 IHABP4_N PF16174.5 EAU90255.2 - 2.7 8.6 14.4 0.3 11.7 4.6 2.5 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal SnoaL_2 PF12680.7 EAU90256.2 - 0.059 14.0 0.0 0.1 13.3 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.20 EAU90256.2 - 0.13 12.8 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Carn_acyltransf PF00755.20 EAU90258.2 - 9.8e-175 582.5 0.0 1.1e-174 582.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase LsmAD PF06741.13 EAU90258.2 - 0.11 13.1 0.2 6.5 7.4 0.0 2.5 2 0 0 2 2 2 0 LsmAD domain DUF4573 PF15140.6 EAU90284.2 - 0.05 13.4 0.1 0.067 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) Plavaka PF18759.1 EAU90285.2 - 3e-18 66.1 0.0 5.3e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase FA_FANCE PF11510.8 EAU90285.2 - 0.14 11.5 0.3 1.2 8.5 0.5 2.0 1 1 1 2 2 2 0 Fanconi Anaemia group E protein FANCE CENP-X PF09415.10 EAU90285.2 - 0.25 11.7 0.8 2.7 8.4 1.1 2.3 1 1 1 2 2 2 0 CENP-S associating Centromere protein X Pkinase PF00069.25 EAU90286.2 - 1.2e-56 192.0 0.0 2.7e-56 190.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU90286.2 - 8e-28 97.4 0.0 1.2e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU90286.2 - 3.1e-09 36.6 0.0 4.5e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAU90286.2 - 3.8e-05 22.7 0.0 7.7e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAU90286.2 - 0.00031 20.2 1.8 0.00089 18.7 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU90286.2 - 0.0043 17.0 0.1 0.0099 15.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EAU90286.2 - 0.082 12.5 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Guanylate_kin PF00625.21 EAU90287.1 - 7.7e-64 214.7 0.0 1e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EAU90287.1 - 3.6e-08 34.0 0.0 7.9e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EAU90287.1 - 5.5e-07 29.8 0.0 5.2e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAU90287.1 - 3.8e-05 24.3 0.0 5.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAU90287.1 - 0.00069 19.9 0.0 0.0016 18.7 0.0 1.8 1 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAU90287.1 - 0.00075 19.4 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 EAU90287.1 - 0.0016 18.8 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 EAU90287.1 - 0.0087 16.0 0.0 0.055 13.4 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EAU90287.1 - 0.0089 16.5 0.0 0.01 16.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.12 EAU90287.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EAU90287.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EAU90287.1 - 0.019 15.0 0.0 0.094 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EAU90287.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAU90287.1 - 0.021 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EAU90287.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EAU90287.1 - 0.026 14.4 0.0 0.074 13.0 0.0 1.8 2 1 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 EAU90287.1 - 0.039 14.4 0.0 0.15 12.4 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EAU90287.1 - 0.059 13.1 0.1 0.13 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAU90287.1 - 0.064 13.2 0.0 0.16 11.8 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA_7 PF12775.7 EAU90287.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EAU90287.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 EAU90287.1 - 0.11 11.7 0.2 1.3 8.2 0.2 2.0 1 1 0 1 1 1 0 KAP family P-loop domain Roc PF08477.13 EAU90287.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 EAU90287.1 - 0.16 11.4 0.0 0.16 11.4 0.0 1.2 1 1 0 1 1 1 0 Poxvirus A32 protein dNK PF01712.19 EAU90287.1 - 0.2 11.5 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_membrane PF00664.23 EAU90288.2 - 1.2e-69 235.1 27.9 5.4e-37 127.9 6.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EAU90288.2 - 1.1e-52 178.2 0.0 1.4e-30 106.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EAU90288.2 - 1.1e-06 28.3 0.0 0.0047 16.4 0.0 3.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EAU90288.2 - 2.5e-05 24.3 0.3 0.24 11.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU90288.2 - 0.00011 22.1 0.1 0.088 12.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EAU90288.2 - 0.00013 21.9 0.1 3.1 7.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF4574 PF15141.6 EAU90288.2 - 0.00016 21.5 0.3 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 AAA_23 PF13476.6 EAU90288.2 - 0.00032 21.3 0.1 0.79 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EAU90288.2 - 0.0004 20.1 0.3 0.08 12.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU90288.2 - 0.00063 20.2 0.2 0.44 10.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EAU90288.2 - 0.0036 17.4 0.3 1.4 9.0 0.1 2.8 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.17 EAU90288.2 - 0.0085 16.2 4.3 0.68 10.0 0.0 2.9 3 0 0 3 3 3 2 Helicase HerA, central domain Zeta_toxin PF06414.12 EAU90288.2 - 0.016 14.5 0.1 1 8.6 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EAU90288.2 - 0.026 14.1 0.6 0.82 9.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EAU90288.2 - 0.042 13.6 0.4 3.1 7.5 0.1 3.0 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EAU90288.2 - 0.066 12.3 0.0 8.5 5.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EAU90288.2 - 0.13 12.5 3.6 7.9 6.8 0.4 3.5 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EAU90288.2 - 0.16 11.7 0.4 11 5.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 EAU90288.2 - 0.19 10.6 0.7 12 4.7 0.3 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain EMP24_GP25L PF01105.24 EAU90290.1 - 2.5e-50 171.0 0.1 3e-50 170.7 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GPI-anchored PF10342.9 EAU90292.1 - 0.0006 20.5 0.0 0.00082 20.1 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family fn3_3 PF14686.6 EAU90292.1 - 0.0031 17.2 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II DUF4448 PF14610.6 EAU90292.1 - 0.14 12.0 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Y_Y_Y PF07495.13 EAU90292.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Y_Y_Y domain Mito_carr PF00153.27 EAU90293.1 - 3.4e-65 216.0 3.3 2.5e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KduI PF04962.12 EAU90293.1 - 0.075 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family Serine_protease PF18405.1 EAU90293.1 - 0.16 11.1 5.1 2.1 7.5 2.0 3.1 1 1 1 2 2 2 0 Gammaproteobacterial serine protease CRISPR_Cse1 PF09481.10 EAU90293.1 - 0.23 10.5 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) CBM_19 PF03427.13 EAU90294.1 - 0.098 12.7 8.6 0.23 11.5 6.2 2.3 1 1 1 2 2 2 0 Carbohydrate binding domain (family 19) PAT1 PF09770.9 EAU90295.2 - 3.7e-95 320.0 98.5 2.5e-91 307.3 31.3 4.2 1 1 3 4 4 4 2 Topoisomerase II-associated protein PAT1 ATAD4 PF15321.6 EAU90295.2 - 2.8 9.3 9.7 1.8 10.0 0.5 3.5 3 1 0 3 3 3 0 ATPase family AAA domain containing 4 hDGE_amylase PF14701.6 EAU90296.1 - 6.5e-169 562.7 0.0 8.6e-169 562.3 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EAU90296.1 - 1.8e-119 399.1 0.0 2.4e-119 398.7 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EAU90296.1 - 1.2e-82 277.4 0.0 1.7e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EAU90296.1 - 8.7e-22 77.1 0.0 1.8e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Ank_2 PF12796.7 EAU90297.2 - 1e-78 259.9 0.0 4.4e-12 46.4 0.0 8.2 1 1 9 10 10 10 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU90297.2 - 4.1e-56 180.3 1.5 0.00035 20.8 0.0 14.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 EAU90297.2 - 2.7e-51 171.0 13.3 2.8e-09 37.0 0.0 11.2 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU90297.2 - 3.3e-44 148.7 3.7 1.3e-06 28.8 0.0 11.0 4 3 9 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 EAU90297.2 - 3.5e-42 141.0 11.5 0.0031 17.9 0.0 13.7 12 2 0 12 12 12 10 Ankyrin repeat NB-ARC PF00931.22 EAU90297.2 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EAU90297.2 - 0.046 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain SLC35F PF06027.12 EAU90298.2 - 5.3e-93 311.8 17.9 6.4e-93 311.5 17.9 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EAU90298.2 - 2.5e-07 30.0 0.3 5.7e-07 28.8 0.3 1.5 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EAU90298.2 - 0.0034 17.5 33.6 0.014 15.6 1.4 3.1 2 1 1 3 3 3 2 EamA-like transporter family Zip PF02535.22 EAU90298.2 - 0.12 11.5 0.1 0.12 11.5 0.1 2.8 3 1 0 3 3 3 0 ZIP Zinc transporter MFA1_2 PF17317.2 EAU90298.2 - 0.34 10.7 0.8 0.98 9.2 0.8 1.8 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 Pribosyltran PF00156.27 EAU90300.1 - 4.9e-05 22.9 0.0 9.6e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FliG_C PF01706.16 EAU90300.1 - 0.13 12.5 0.0 6.5 7.0 0.0 2.2 2 0 0 2 2 2 0 FliG C-terminal domain RNA_pol_Rpc4 PF05132.14 EAU90301.1 - 1.8e-34 119.3 0.0 1.8e-34 119.3 0.0 2.7 3 1 0 3 3 3 1 RNA polymerase III RPC4 FYDLN_acid PF09538.10 EAU90301.1 - 2.3 8.9 13.1 5 7.8 5.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Fungal_trans PF04082.18 EAU90302.2 - 6e-05 22.2 0.6 0.29 10.1 0.0 2.9 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU90302.2 - 0.00021 21.4 12.7 0.00044 20.3 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 EAU90302.2 - 0.26 10.9 0.8 0.79 9.3 0.8 1.8 1 0 0 1 1 1 0 Trimerisation motif TFIID_30kDa PF03540.13 EAU90303.1 - 1.6e-26 92.0 0.1 5.6e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 EAU90303.1 - 0.0019 18.1 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 Bromodomain associated FoP_duplication PF13865.6 EAU90303.1 - 0.027 15.0 1.3 0.29 11.7 0.1 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 SPATA3 PF15662.5 EAU90303.1 - 6.5 7.3 9.2 9.3 6.8 9.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family FAD_binding_3 PF01494.19 EAU90304.2 - 6.6e-20 71.7 0.0 1.1e-19 70.9 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EAU90304.2 - 2.3e-06 27.1 0.0 0.048 12.9 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU90304.2 - 0.00013 21.6 0.1 0.16 11.5 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU90304.2 - 0.00052 20.2 0.0 0.0015 18.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EAU90304.2 - 0.0026 16.5 0.2 0.011 14.4 0.2 1.8 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EAU90304.2 - 0.0085 15.4 0.5 0.71 9.1 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase zf-C3HC4 PF00097.25 EAU90305.2 - 5e-08 32.7 4.5 5e-08 32.7 4.5 6.7 4 3 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU90305.2 - 2.6e-06 27.7 4.9 2.6e-06 27.7 4.9 5.6 4 2 2 6 6 6 1 Ring finger domain IBR PF01485.21 EAU90305.2 - 9.1e-06 25.8 6.3 9.1e-06 25.8 6.3 4.0 3 0 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 EAU90305.2 - 6e-05 22.9 5.7 6e-05 22.9 5.7 4.5 3 2 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU90305.2 - 0.00028 20.8 6.5 0.00028 20.8 6.5 4.0 3 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAU90305.2 - 0.00034 20.4 7.4 0.00034 20.4 7.4 5.8 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU90305.2 - 0.0055 16.6 3.4 0.0055 16.6 3.4 6.0 4 3 3 7 7 7 1 Zinc finger, C3HC4 type (RING finger) DUF484 PF04340.12 EAU90305.2 - 0.094 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Zip PF02535.22 EAU90307.1 - 4.1e-58 197.2 11.3 4.1e-58 197.2 11.3 2.0 1 1 1 2 2 2 1 ZIP Zinc transporter Brix PF04427.18 EAU90309.2 - 3.3e-22 79.6 0.0 5.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Brix domain DUF4604 PF15377.6 EAU90310.2 - 9.8e-22 78.2 20.2 1.4e-21 77.7 20.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Methyltransf_11 PF08241.12 EAU90311.1 - 2.8e-15 56.8 0.0 5.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU90311.1 - 1e-14 55.0 0.1 4.8e-14 52.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU90311.1 - 1.1e-11 44.7 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU90311.1 - 2.9e-06 27.2 0.0 7.7e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EAU90311.1 - 3e-05 23.5 0.2 0.083 12.2 0.1 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EAU90311.1 - 0.014 15.4 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 EAU90311.1 - 0.03 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EAU90311.1 - 0.042 13.4 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain MetW PF07021.12 EAU90311.1 - 0.054 13.1 0.1 0.17 11.5 0.1 1.8 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 EAU90311.1 - 0.07 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TT1725 PF18324.1 EAU90311.1 - 0.11 12.6 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 Hypothetical protein TT1725 Methyltransf_28 PF02636.17 EAU90312.2 - 2.5e-40 138.7 0.0 3.5e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 EAU90312.2 - 0.0012 18.0 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EAU90312.2 - 0.0049 17.6 0.0 0.018 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain HTH_ABP1_N PF18107.1 EAU90312.2 - 0.021 14.6 0.2 12 5.7 0.0 2.8 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain PRMT5 PF05185.16 EAU90312.2 - 0.033 14.0 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MMS19_C PF12460.8 EAU90313.2 - 3.4e-119 398.7 6.3 9.5e-119 397.2 6.3 1.8 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EAU90313.2 - 1.5e-90 303.3 0.0 2.7e-87 292.7 0.0 4.1 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EAU90313.2 - 4.5e-08 33.4 0.8 0.0092 16.5 0.0 5.2 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 EAU90313.2 - 1.1e-07 32.1 1.2 0.045 14.2 0.0 5.4 4 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EAU90313.2 - 6.4e-05 22.9 0.8 3.5 8.1 0.0 6.0 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.8 EAU90313.2 - 0.013 15.1 0.0 0.24 10.9 0.0 3.3 2 1 1 3 3 3 0 CLASP N terminal Cnd1 PF12717.7 EAU90313.2 - 0.025 14.6 0.5 13 5.8 0.0 3.8 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DNA_pol_phi PF04931.13 EAU90313.2 - 0.028 12.5 0.3 1.7 6.6 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase phi TAF6_C PF07571.13 EAU90313.2 - 0.028 14.7 0.0 0.65 10.4 0.0 3.2 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain SCA7 PF08313.12 EAU90315.1 - 1.1e-27 95.7 0.2 1.1e-27 95.7 0.2 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain MFAP1 PF06991.11 EAU90315.1 - 0.015 15.2 8.1 0.023 14.5 8.1 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Rrn6 PF10214.9 EAU90315.1 - 0.063 11.8 1.0 0.075 11.5 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Erythro_esteras PF05139.14 EAU90315.1 - 3 7.6 7.4 4.2 7.1 7.4 1.1 1 0 0 1 1 1 0 Erythromycin esterase DSBA PF01323.20 EAU90315.1 - 5.4 6.8 6.1 20 4.9 4.1 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF3138 PF11336.8 EAU90315.1 - 6.8 5.2 6.4 9.1 4.8 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MAS20 PF02064.15 EAU90315.1 - 7 6.8 13.2 23 5.1 13.2 1.8 1 1 0 1 1 1 0 MAS20 protein import receptor Macoilin PF09726.9 EAU90315.1 - 7.5 5.0 9.4 11 4.4 9.4 1.1 1 0 0 1 1 1 0 Macoilin family FF PF01846.19 EAU90316.2 - 2.7e-40 136.3 6.5 3.7e-14 52.6 0.1 5.9 5 1 0 5 5 5 5 FF domain WW PF00397.26 EAU90316.2 - 1.2e-12 47.7 16.7 3e-06 27.2 4.6 2.7 2 0 0 2 2 2 2 WW domain Ribosomal_L21p PF00829.21 EAU90317.1 - 1.8e-23 82.7 0.9 2.2e-23 82.4 0.9 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF5011 PF16403.5 EAU90317.1 - 0.16 12.1 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) EZH2_N PF18601.1 EAU90317.1 - 0.21 12.0 1.1 0.46 10.9 0.0 1.9 2 0 0 2 2 2 0 EZH2 N-terminal domain ATP-synt_ab PF00006.25 EAU90318.2 - 6.2e-73 245.0 0.0 8.5e-73 244.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EAU90318.2 - 2.7e-43 147.3 0.2 4.4e-43 146.6 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EAU90318.2 - 1.8e-17 63.6 1.2 4.2e-17 62.4 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Aldedh PF00171.22 EAU90319.1 - 3.4e-17 62.1 7.9 5.3e-14 51.6 4.1 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family ANTH PF07651.16 EAU90322.2 - 6.2e-50 169.7 0.3 9.4e-50 169.1 0.3 1.3 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 EAU90322.2 - 0.005 17.2 30.5 0.005 17.2 30.5 9.0 1 1 5 7 7 7 4 Domain of unknown function (DUF1720) ENTH PF01417.20 EAU90322.2 - 0.058 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 ENTH domain Glyco_hydro_47 PF01532.20 EAU90323.2 - 3.9e-129 431.5 0.0 4.9e-129 431.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FGGY_N PF00370.21 EAU90324.2 - 3.9e-61 206.7 0.2 7.2e-60 202.6 0.2 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EAU90324.2 - 6.8e-61 205.5 2.1 1.2e-60 204.6 2.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CHAT PF12770.7 EAU90325.1 - 5.2e-32 111.4 0.0 8.6e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EAU90325.1 - 0.00031 20.5 4.5 4.8 7.2 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90325.1 - 0.37 11.7 7.1 23 6.1 0.1 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU90326.2 - 6.2e-47 156.3 3.4 2e-05 24.3 0.0 14.1 15 0 0 15 15 15 10 Tetratricopeptide repeat CHAT PF12770.7 EAU90326.2 - 5.9e-29 101.4 0.0 1.9e-28 99.7 0.0 1.9 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.6 EAU90326.2 - 1.1e-12 48.1 11.2 0.03 14.6 0.0 11.4 9 3 5 14 14 14 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90326.2 - 1.7e-06 27.7 0.2 30 5.2 0.0 9.0 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90326.2 - 0.00032 20.4 6.7 16 5.6 0.0 8.1 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU90326.2 - 0.00047 20.0 1.6 21 5.6 0.0 8.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 EAU90326.2 - 0.022 14.4 0.0 14 5.4 0.0 5.2 7 0 0 7 7 7 0 TPR repeat DUF4164 PF13747.6 EAU90326.2 - 0.54 10.6 6.6 93 3.4 0.0 6.9 8 1 1 9 9 9 0 Domain of unknown function (DUF4164) DUF1640 PF07798.11 EAU90327.1 - 6.4e-60 202.2 11.3 7.3e-60 202.0 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DotU PF09850.9 EAU90327.1 - 0.11 12.2 4.9 2.6 7.7 0.1 3.0 2 1 0 2 2 2 0 Type VI secretion system protein DotU CrtC PF07143.11 EAU90327.1 - 0.62 10.7 3.3 4.8 7.8 3.3 2.1 1 1 0 1 1 1 0 CrtC N-terminal lipocalin domain FlaC_arch PF05377.11 EAU90327.1 - 0.87 10.0 7.0 0.22 11.9 0.8 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GTA_holin_3TM PF11351.8 EAU90327.1 - 1 9.9 5.5 1.1 9.9 4.6 1.5 1 1 0 1 1 1 0 Holin of 3TMs, for gene-transfer release DivIC PF04977.15 EAU90327.1 - 1.5 8.6 10.2 0.41 10.5 5.1 2.5 2 1 1 3 3 3 0 Septum formation initiator Fungal_TACC PF12709.7 EAU90327.1 - 3.3 8.2 9.1 8 7.0 5.8 2.7 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF2781 PF10914.8 EAU90328.2 - 1e-14 55.1 1.5 1e-14 55.1 1.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) WD40 PF00400.32 EAU90329.1 - 7.8e-09 36.0 0.3 0.023 15.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Polysacc_deac_1 PF01522.21 EAU90331.1 - 1.3e-27 96.1 0.0 2.4e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Sec1 PF00995.23 EAU90332.1 - 2.5e-131 439.7 0.0 2.9e-131 439.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AAA PF00004.29 EAU90333.1 - 9.3e-43 145.8 0.0 1.8e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU90333.1 - 3.2e-11 42.8 0.3 7.6e-11 41.6 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EAU90333.1 - 3.5e-10 39.7 1.3 4.4e-10 39.3 0.1 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EAU90333.1 - 1.1e-07 32.4 0.0 8.4e-05 23.0 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EAU90333.1 - 1.6e-07 31.4 0.1 1.5e-06 28.2 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EAU90333.1 - 6e-06 26.5 0.0 2.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAU90333.1 - 8.7e-06 25.6 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAU90333.1 - 0.00015 22.0 0.1 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 EAU90333.1 - 0.0011 18.5 0.2 0.0042 16.7 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 EAU90333.1 - 0.0013 19.2 0.0 0.0056 17.2 0.0 2.0 1 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 EAU90333.1 - 0.0014 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 EAU90333.1 - 0.0032 16.7 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EAU90333.1 - 0.0034 16.8 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EAU90333.1 - 0.0043 17.0 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EAU90333.1 - 0.0052 16.5 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 EAU90333.1 - 0.0053 16.3 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EAU90333.1 - 0.0054 17.1 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EAU90333.1 - 0.0095 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EAU90333.1 - 0.012 16.2 4.7 10 6.5 5.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EAU90333.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EAU90333.1 - 0.015 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAU90333.1 - 0.016 14.9 0.0 0.054 13.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 EAU90333.1 - 0.018 14.5 0.1 0.041 13.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 EAU90333.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EAU90333.1 - 0.021 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAU90333.1 - 0.028 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU90333.1 - 0.053 13.1 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.15 EAU90333.1 - 0.065 13.5 0.3 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 Mnd1 HTH domain NACHT PF05729.12 EAU90333.1 - 0.067 13.1 0.0 0.18 11.7 0.0 1.7 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.6 EAU90333.1 - 0.076 12.8 2.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EAU90333.1 - 0.079 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EAU90333.1 - 0.083 12.2 1.5 0.18 11.2 0.0 2.2 3 0 0 3 3 3 0 KaiC AAA_19 PF13245.6 EAU90333.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Torus PF16131.5 EAU90334.2 - 4.1e-20 72.5 32.8 0.0053 17.4 0.0 8.8 6 2 2 8 8 8 6 Torus domain zf-CCCH PF00642.24 EAU90334.2 - 5.1e-19 67.7 55.6 8.1e-05 22.4 1.9 8.2 8 0 0 8 8 8 7 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAU90334.2 - 4.1e-15 55.3 81.9 3.6e-05 23.7 4.1 8.5 9 0 0 9 9 8 6 Zinc finger domain RRM_1 PF00076.22 EAU90334.2 - 5.1e-13 48.6 0.1 0.00054 19.7 0.0 5.0 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 EAU90334.2 - 6.8e-11 41.7 74.0 6.8e-06 25.8 4.5 8.6 9 0 0 9 9 8 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EAU90334.2 - 1.8e-06 28.1 29.7 0.13 12.4 3.6 7.6 7 1 0 7 7 7 3 Zinc-finger containing family IBR PF01485.21 EAU90334.2 - 2.3e-06 27.7 2.0 2.3e-06 27.7 2.0 2.9 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain zf-CCCH_2 PF14608.6 EAU90334.2 - 0.0001 22.7 60.8 0.041 14.4 1.2 8.1 8 0 0 8 8 7 4 RNA-binding, Nab2-type zinc finger zf-RING_UBOX PF13445.6 EAU90334.2 - 0.00014 21.8 3.2 0.00058 19.8 3.2 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAU90334.2 - 0.00025 20.8 2.9 0.00025 20.8 2.9 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU90334.2 - 0.00092 19.0 1.5 0.00092 19.0 1.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf_CopZ PF18423.1 EAU90334.2 - 0.014 15.4 3.1 0.023 14.6 0.5 2.5 2 0 0 2 2 2 0 Zinc binding domain zf-RING_2 PF13639.6 EAU90334.2 - 0.014 15.7 1.4 0.014 15.7 1.4 4.5 5 0 0 5 5 4 0 Ring finger domain zf-RING_5 PF14634.6 EAU90334.2 - 0.017 15.1 0.8 0.017 15.1 0.8 2.9 2 0 0 2 2 1 0 zinc-RING finger domain RRM_occluded PF16842.5 EAU90334.2 - 0.024 14.5 0.3 0.99 9.3 0.1 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Prok-RING_4 PF14447.6 EAU90334.2 - 0.86 9.5 11.6 0.13 12.1 3.0 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAU90334.2 - 2.6 8.0 12.1 0.067 13.0 2.3 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 EAU90334.2 - 2.8 8.2 11.7 0.88 9.8 2.4 2.8 2 0 0 2 2 2 0 B-box zinc finger Glyco_transf_90 PF05686.12 EAU90335.2 - 1e-17 64.2 1.7 3.2e-17 62.5 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 90 FTZ PF03867.14 EAU90335.2 - 0.0019 17.8 0.1 0.061 12.9 0.0 2.2 2 0 0 2 2 2 1 Fushi tarazu (FTZ), N-terminal region 5_nucleotid_C PF02872.18 EAU90336.2 - 7e-23 81.6 0.0 1.3e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EAU90336.2 - 3.6e-08 34.2 0.2 6.7e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_M20 PF01546.28 EAU90337.2 - 9.7e-18 64.6 0.0 3.7e-17 62.7 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAU90337.2 - 4.8e-11 42.6 0.0 9.3e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans PF04082.18 EAU90340.1 - 5.7e-17 61.6 0.4 1e-16 60.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU90340.1 - 4e-06 26.8 10.8 7e-06 26.1 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YIEGIA PF14045.6 EAU90340.1 - 0.036 12.9 0.1 0.092 11.6 0.1 1.7 1 1 0 1 1 1 0 YIEGIA protein PDCD2_C PF04194.13 EAU90341.2 - 3.4e-43 147.7 0.4 3.4e-43 147.7 0.4 2.0 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain SHE3 PF17078.5 EAU90342.1 - 0.013 15.2 2.1 0.31 10.7 0.4 2.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF3243 PF11588.8 EAU90342.1 - 0.049 13.9 1.0 0.2 12.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) Bap31_Bap29_C PF18035.1 EAU90342.1 - 0.055 13.5 0.3 0.055 13.5 0.3 3.3 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2153 PF09921.9 EAU90342.1 - 0.077 12.8 2.3 21 5.0 0.1 3.7 3 2 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2153) DUF948 PF06103.11 EAU90342.1 - 1.2 9.5 5.6 3.5 7.9 0.4 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1779 PF08680.10 EAU90342.1 - 1.3 9.2 10.2 1 9.5 2.3 2.4 2 0 0 2 2 2 0 TATA-box binding Nitroreductase PF00881.24 EAU90343.1 - 8.5e-28 97.5 0.0 1.5e-27 96.7 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EAU90343.1 - 1.9e-08 34.2 0.0 0.0016 18.1 0.0 3.1 2 1 1 3 3 3 3 Putative TM nitroreductase DUF3420 PF11900.8 EAU90343.1 - 0.054 13.6 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) DUF1805 PF08827.11 EAU90343.1 - 0.13 12.6 0.0 7.4 7.0 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1805) Rho_N PF07498.12 EAU90344.2 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain ZapB PF06005.12 EAU90344.2 - 2.2 8.8 6.8 0.21 12.0 1.9 1.8 2 0 0 2 2 2 0 Cell division protein ZapB DUF2624 PF11116.8 EAU90345.1 - 0.34 11.8 4.4 0.34 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Amidase PF01425.21 EAU90346.2 - 2.5e-92 310.2 0.0 2.5e-91 306.9 0.0 2.0 1 1 0 1 1 1 1 Amidase Peptidase_M50B PF13398.6 EAU90348.2 - 8.8e-34 116.9 15.7 1.2e-33 116.5 15.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Fis1_TPR_C PF14853.6 EAU90349.2 - 5.3e-24 84.1 1.9 8.3e-24 83.4 1.9 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EAU90349.2 - 1.9e-15 56.2 0.0 3.4e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EAU90349.2 - 0.00027 20.8 1.3 0.00072 19.5 1.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90349.2 - 0.015 15.1 1.9 0.037 13.9 1.9 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAU90349.2 - 0.023 15.2 1.2 0.026 15.0 0.2 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAU90349.2 - 0.024 15.3 0.5 0.063 13.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU90349.2 - 0.055 13.7 0.5 0.09 13.0 0.5 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 RRM_1 PF00076.22 EAU90350.2 - 2e-31 107.6 4.9 2.7e-15 55.9 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU90350.2 - 1.3e-06 28.4 0.0 0.00099 19.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EAU90350.2 - 0.00028 20.7 0.0 0.2 11.5 0.0 3.4 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_9 PF18444.1 EAU90350.2 - 0.053 13.4 0.0 9.4 6.2 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EAU90350.2 - 0.058 13.4 0.3 42 4.2 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Amidase PF01425.21 EAU90351.1 - 1.1e-104 350.9 0.0 1.3e-104 350.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Histone_H2A_C PF16211.5 EAU90352.2 - 1.7e-06 27.7 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EAU90352.2 - 0.00076 19.8 0.2 0.0015 18.9 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EAU90352.2 - 0.042 14.0 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) dsrm PF00035.26 EAU90353.1 - 8.2e-10 39.3 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EAU90353.1 - 2e-08 34.4 0.0 4.6e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EAU90353.1 - 0.021 15.4 0.0 0.13 12.9 0.0 2.3 1 1 0 1 1 1 0 Ribonuclease III domain RhoGAP PF00620.27 EAU90354.2 - 1.4e-11 44.5 0.4 5.2e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EAU90354.2 - 1.3e-05 25.4 0.0 4.7e-05 23.6 0.0 2.1 2 0 0 2 2 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 EAU90354.2 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Nop14 PF04147.12 EAU90354.2 - 0.21 9.8 9.5 0.47 8.6 9.5 1.5 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EAU90354.2 - 0.5 9.7 9.2 0.95 8.8 9.2 1.4 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 EAU90354.2 - 2 6.9 10.6 3.6 6.1 10.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sporozoite_P67 PF05642.11 EAU90354.2 - 2.8 5.9 13.5 0.073 11.2 6.5 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen YL1 PF05764.13 EAU90354.2 - 3.5 7.7 16.5 0.018 15.1 6.4 2.3 3 0 0 3 3 3 0 YL1 nuclear protein CDC45 PF02724.14 EAU90354.2 - 4.5 5.5 12.5 7 4.8 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EAU90354.2 - 4.8 7.2 11.4 11 6.0 11.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal eIF-3c_N PF05470.12 EAU90354.2 - 5.4 5.2 6.3 2.8 6.1 4.3 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SAGA-Tad1 PF12767.7 EAU90356.1 - 2.1e-26 93.1 0.0 3.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 EAU90356.1 - 7.1e-05 22.7 0.4 0.00012 21.9 0.1 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family WD40 PF00400.32 EAU90357.2 - 0.01 16.7 5.0 5.8 8.0 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40_like PF17005.5 EAU90357.2 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 EAU90357.2 - 0.31 11.6 1.5 18 6.0 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain Ank_2 PF12796.7 EAU90358.1 - 5.1e-42 142.3 0.2 4.1e-13 49.7 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU90358.1 - 8e-27 90.4 1.1 0.00012 22.2 0.0 6.1 6 0 0 6 6 5 5 Ankyrin repeat Ank_5 PF13857.6 EAU90358.1 - 1.2e-26 92.4 1.5 1.2e-08 35.1 0.0 4.5 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAU90358.1 - 1.5e-22 78.9 1.3 0.00018 21.8 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EAU90358.1 - 2.5e-17 63.0 0.2 5.3e-07 30.1 0.3 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.12 EAU90358.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EAU90358.1 - 0.00014 21.2 0.2 0.00045 19.5 0.2 1.8 1 1 0 1 1 1 1 NB-ARC domain VWA_3_C PF18571.1 EAU90358.1 - 0.0022 17.8 2.0 2.5 8.1 0.2 3.8 4 0 0 4 4 4 2 von Willebrand factor type A C-terminal domain AAA_22 PF13401.6 EAU90358.1 - 0.0053 17.0 0.0 0.021 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU90358.1 - 0.011 16.2 0.0 0.12 12.8 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain DUF463 PF04317.12 EAU90358.1 - 0.03 13.2 0.4 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 YcjX-like family, DUF463 RNase_H PF00075.24 EAU90359.2 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 EAU90359.2 - 0.02 15.6 1.4 0.045 14.5 1.1 1.9 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase CE2_N PF17996.1 EAU90361.1 - 3.7e-06 26.9 0.0 0.0045 16.9 0.0 2.8 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal DUF456 PF04306.13 EAU90361.1 - 0.058 13.7 0.6 0.095 13.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF2207 PF09972.9 EAU90361.1 - 0.062 12.1 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) F-box-like PF12937.7 EAU90362.2 - 0.045 13.7 8.8 0.18 11.7 8.8 2.1 1 1 0 1 1 1 0 F-box-like NdhL PF10716.9 EAU90364.2 - 0.031 14.2 0.8 0.031 14.2 0.8 2.7 3 0 0 3 3 3 0 NADH dehydrogenase transmembrane subunit Actin PF00022.19 EAU90365.1 - 1.2e-116 389.7 0.0 5.2e-116 387.6 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EAU90365.1 - 0.012 14.4 0.0 0.033 13.0 0.0 1.6 1 1 0 1 1 1 0 MreB/Mbl protein Phos_pyr_kin PF08543.12 EAU90366.1 - 1.1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EAU90366.1 - 6.4e-06 25.7 0.0 1.7e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase START PF01852.19 EAU90367.2 - 1.6e-08 34.2 0.0 6.9e-06 25.6 0.0 2.9 3 0 0 3 3 3 2 START domain LisH PF08513.11 EAU90368.2 - 0.004 17.1 0.1 0.0064 16.4 0.1 1.3 1 0 0 1 1 1 1 LisH BTB PF00651.31 EAU90369.1 - 5.9e-05 23.3 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Cnn_1N PF07989.11 EAU90373.2 - 0.053 13.7 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Herpes_BLRF2 PF05812.12 EAU90373.2 - 0.11 12.6 0.1 9.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein HALZ PF02183.18 EAU90373.2 - 0.22 11.8 1.2 2.4 8.5 0.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Myc-LZ PF02344.15 EAU90373.2 - 5.8 7.1 5.9 0.89 9.7 1.4 2.0 2 0 0 2 2 2 0 Myc leucine zipper domain Ribosomal_L5_C PF00673.21 EAU90374.2 - 3.2e-21 75.3 0.0 5e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EAU90374.2 - 2.2e-18 66.3 0.0 2.2e-18 66.3 0.0 1.9 3 0 0 3 3 3 1 Ribosomal protein L5 ATG16 PF08614.11 EAU90375.2 - 0.0011 19.2 25.4 0.27 11.4 6.2 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EAU90375.2 - 0.016 15.3 5.6 0.016 15.3 5.6 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.11 EAU90375.2 - 0.04 14.3 5.3 0.94 9.9 1.1 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EAU90375.2 - 0.045 14.4 14.8 0.6 10.8 5.8 2.8 1 1 1 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 EAU90375.2 - 0.076 13.3 17.3 1.1 9.5 4.0 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain MiaE_2 PF13794.6 EAU90375.2 - 0.094 12.4 1.3 0.25 11.0 0.1 1.9 1 1 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF812 PF05667.11 EAU90375.2 - 0.17 10.7 22.0 4.2 6.1 18.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 EAU90375.2 - 0.19 10.4 18.5 0.26 9.9 18.5 1.2 1 0 0 1 1 1 0 AAA domain KASH_CCD PF14662.6 EAU90375.2 - 0.23 11.2 21.1 2.6 7.8 21.1 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4200 PF13863.6 EAU90375.2 - 0.26 11.7 29.8 0.21 12.0 14.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1729 PF08354.10 EAU90375.2 - 0.29 10.0 4.5 0.43 9.4 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) zf-C4H2 PF10146.9 EAU90375.2 - 0.31 11.3 12.7 9.8 6.4 12.6 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein CENP-K PF11802.8 EAU90375.2 - 0.42 10.2 14.8 0.71 9.4 14.1 1.6 1 1 1 2 2 2 0 Centromere-associated protein K CorA PF01544.18 EAU90375.2 - 0.48 9.7 12.7 0.84 8.9 11.4 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein UPF0242 PF06785.11 EAU90375.2 - 0.73 9.9 24.3 4.3 7.4 24.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 EAU90375.2 - 0.76 10.0 20.6 0.13 12.5 7.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 EAU90375.2 - 0.79 8.5 23.5 0.78 8.5 9.7 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CREPT PF16566.5 EAU90375.2 - 0.94 9.6 18.0 0.21 11.7 7.7 2.4 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour T3SSipB PF16535.5 EAU90375.2 - 2 8.9 16.2 6.7 7.2 5.2 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB GAS PF13851.6 EAU90375.2 - 2.2 7.6 27.7 3.5 6.9 14.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding BMFP PF04380.13 EAU90375.2 - 3.2 8.3 12.9 0.78 10.3 0.6 3.3 3 1 0 3 3 2 0 Membrane fusogenic activity APG6_N PF17675.1 EAU90375.2 - 3.4 8.2 28.0 5.4 7.5 10.4 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 EAU90375.2 - 3.4 7.7 12.1 1.6 8.8 4.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 EAU90375.2 - 3.4 6.1 7.3 2.3 6.6 5.6 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family PIN_8 PF18476.1 EAU90375.2 - 4 7.2 15.9 0.54 10.1 4.1 2.3 1 1 1 2 2 2 0 PIN like domain Phage_GPO PF05929.11 EAU90375.2 - 4 7.0 16.1 2.4 7.7 6.6 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Mod_r PF07200.13 EAU90375.2 - 6.3 6.9 20.2 1e+04 -3.5 20.2 2.3 1 1 0 1 1 0 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.8 EAU90375.2 - 6.4 6.0 22.3 4 6.7 8.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 EAU90375.2 - 7.3 7.3 14.9 2.6 8.8 2.9 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) kleA_kleC PF17383.2 EAU90375.2 - 8.6 6.8 17.1 2.9 8.3 2.6 3.9 1 1 2 4 4 4 0 Uncharacterized KorC regulated protein A Podoplanin PF05808.11 EAU90380.1 - 2.3e-07 31.1 0.4 2.3e-07 31.1 0.4 2.0 2 0 0 2 2 2 1 Podoplanin PMP1_2 PF08114.11 EAU90380.1 - 0.038 13.7 0.1 0.088 12.6 0.1 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Apt1 PF10351.9 EAU90380.1 - 1.6 7.5 4.2 2.5 6.8 4.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-LITAF-like PF10601.9 EAU90381.2 - 0.11 12.8 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Syndecan PF01034.20 EAU90381.2 - 0.27 11.2 0.1 0.52 10.3 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain USP7_ICP0_bdg PF12436.8 EAU90382.2 - 1.7e-27 96.3 0.1 1.7e-23 83.2 0.0 2.9 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 EAU90382.2 - 1.5e-11 44.3 0.0 2.8e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4293 PF14126.6 EAU90383.1 - 0.012 15.9 0.2 0.021 15.1 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3377 PF11857.8 EAU90383.1 - 0.14 12.1 0.6 0.88 9.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Gpi1 PF05024.15 EAU90383.1 - 0.15 12.1 1.9 0.31 11.1 1.6 1.7 1 1 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) Glyco_trans_2_3 PF13632.6 EAU90383.1 - 1.4 8.8 6.1 3.9 7.3 6.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Med20 PF08612.11 EAU90384.2 - 1.8e-11 43.8 0.0 5.4e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex AAA_16 PF13191.6 EAU90385.2 - 1.6e-16 61.2 0.1 4.2e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain ORC4_C PF14629.6 EAU90385.2 - 2.9e-14 53.0 0.0 3.8e-13 49.3 0.0 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 EAU90385.2 - 0.00028 21.3 0.0 0.0063 16.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAU90385.2 - 0.002 18.4 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAU90385.2 - 0.023 13.9 0.0 0.098 11.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EAU90385.2 - 0.028 14.4 0.0 0.091 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EAU90385.2 - 0.041 14.1 1.8 0.24 11.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EAU90385.2 - 0.041 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EAU90385.2 - 0.086 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 EAU90385.2 - 0.11 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EAU90385.2 - 0.15 11.9 0.0 8.3 6.3 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Glycos_transf_2 PF00535.26 EAU90386.1 - 1.3e-21 77.2 0.0 3.2e-21 75.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EAU90386.1 - 1.8e-07 31.3 0.0 1.4e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EAU90386.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EAU90386.1 - 0.098 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ran_BP1 PF00638.18 EAU90388.2 - 2e-14 53.9 0.0 3.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain HATPase_c PF02518.26 EAU90389.2 - 4.9e-20 72.1 0.0 1.9e-19 70.2 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EAU90389.2 - 3e-19 69.2 0.1 6.1e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain zf-HC5HC2H_2 PF13832.6 EAU90390.2 - 2.1e-20 72.9 29.3 1.5e-19 70.1 4.7 4.3 3 2 0 3 3 3 3 PHD-zinc-finger like domain PHD PF00628.29 EAU90390.2 - 5.9e-15 54.9 55.4 1e-08 34.9 9.1 5.7 5 0 0 5 5 5 4 PHD-finger zf-HC5HC2H PF13771.6 EAU90390.2 - 2.2e-14 53.5 5.8 2.2e-14 53.5 5.8 4.6 3 2 1 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.18 EAU90390.2 - 3e-10 40.0 0.0 7.6e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.6 EAU90390.2 - 1.2e-06 27.9 31.6 0.00027 20.4 2.6 5.8 5 0 0 5 5 5 4 PHD-finger C1_1 PF00130.22 EAU90390.2 - 1.4e-06 28.1 47.6 0.0053 16.6 5.7 6.4 6 0 0 6 6 6 4 Phorbol esters/diacylglycerol binding domain (C1 domain) GATA PF00320.27 EAU90390.2 - 0.00023 20.7 6.4 0.00023 20.7 6.4 4.0 4 0 0 4 4 4 1 GATA zinc finger AT_hook PF02178.19 EAU90390.2 - 0.027 14.3 2.4 0.09 12.7 2.4 2.0 1 0 0 1 1 1 0 AT hook motif C1_2 PF03107.16 EAU90390.2 - 3 8.2 45.7 0.13 12.6 1.4 6.9 8 0 0 8 8 8 0 C1 domain UCH PF00443.29 EAU90391.2 - 2.3e-68 230.5 0.0 3.7e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAU90391.2 - 2.1e-17 63.7 0.0 2.4e-15 56.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EAU90391.2 - 2.6e-07 31.1 0.0 5.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF357 PF04010.13 EAU90391.2 - 0.13 12.4 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Peptidase_C98 PF15499.6 EAU90391.2 - 0.28 10.6 0.7 12 5.3 0.5 2.9 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ADIP PF11559.8 EAU90393.2 - 3.7e-25 88.8 10.8 3.7e-25 88.8 10.8 3.6 2 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 EAU90393.2 - 0.00021 21.8 13.2 0.00021 21.8 13.2 2.6 2 0 0 2 2 2 1 Fez1 DUF4407 PF14362.6 EAU90393.2 - 0.00029 20.3 30.0 0.0014 18.0 12.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EAU90393.2 - 0.0023 17.6 23.8 0.11 12.1 6.5 2.2 2 0 0 2 2 2 2 Exonuclease VII, large subunit DUF1043 PF06295.12 EAU90393.2 - 0.0067 16.4 7.5 0.0067 16.4 7.5 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1043) T7SS_ESX_EspC PF10824.8 EAU90393.2 - 0.014 15.9 1.7 0.014 15.9 1.7 3.8 3 1 1 4 4 3 0 Excreted virulence factor EspC, type VII ESX diderm AIP3 PF03915.13 EAU90393.2 - 0.038 13.1 22.0 0.071 12.2 3.3 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 Golgin_A5 PF09787.9 EAU90393.2 - 0.046 13.2 40.1 0.11 11.9 14.6 2.5 3 0 0 3 3 3 0 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 EAU90393.2 - 0.079 13.5 0.0 0.079 13.5 0.0 4.4 2 2 2 4 4 4 0 Syntaxin 6, N-terminal AAA_23 PF13476.6 EAU90393.2 - 0.82 10.1 22.7 0.38 11.2 6.3 2.6 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 EAU90393.2 - 0.9 9.9 44.5 0.33 11.3 9.4 3.4 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.8 EAU90393.2 - 1.1 6.7 39.8 1.4 6.3 16.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3040 PF11239.8 EAU90393.2 - 1.8 8.9 4.4 4.7 7.6 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Filament PF00038.21 EAU90393.2 - 1.9 8.0 31.4 2.6 7.5 8.6 2.6 2 1 0 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 EAU90393.2 - 2.1 8.5 19.8 0.062 13.5 3.0 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 EAU90393.2 - 2.3 6.7 26.0 0.54 8.8 0.7 3.0 2 1 1 3 3 3 0 Flagellar Assembly Protein A LMBR1 PF04791.16 EAU90393.2 - 3.4 6.4 15.9 3.5 6.4 4.2 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Atg14 PF10186.9 EAU90393.2 - 4.3 6.3 32.5 0.14 11.2 12.2 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EAU90393.2 - 4.4 6.5 23.8 0.47 9.7 9.2 2.4 2 0 0 2 2 2 0 TMPIT-like protein FAM184 PF15665.5 EAU90393.2 - 4.5 7.0 36.6 3.3 7.4 11.5 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Spc7 PF08317.11 EAU90393.2 - 7.1 5.4 41.5 0.39 9.5 5.2 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4140 PF13600.6 EAU90393.2 - 9.5 6.7 31.2 0.21 12.1 0.4 4.4 4 1 1 5 5 4 0 N-terminal domain of unknown function (DUF4140) PTP_tm PF18861.1 EAU90396.2 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J F-box-like PF12937.7 EAU90397.2 - 2.2e-06 27.5 1.3 2.2e-06 27.5 1.3 3.0 4 0 0 4 4 4 1 F-box-like F-box-like_2 PF13013.6 EAU90397.2 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain DUF1664 PF07889.12 EAU90399.2 - 0.00018 21.5 12.3 0.00046 20.2 6.7 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) APG17 PF04108.12 EAU90399.2 - 0.00033 19.9 9.0 0.00046 19.4 9.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg17 AAA_13 PF13166.6 EAU90399.2 - 0.0057 15.4 14.8 0.0078 14.9 14.8 1.1 1 0 0 1 1 1 1 AAA domain FH2 PF02181.23 EAU90399.2 - 0.006 15.8 5.4 0.006 15.8 5.4 2.2 1 1 1 2 2 2 1 Formin Homology 2 Domain TPR_MLP1_2 PF07926.12 EAU90399.2 - 0.007 16.4 21.1 0.007 16.4 21.1 2.5 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein EzrA PF06160.12 EAU90399.2 - 0.013 13.7 16.1 0.022 12.9 16.1 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.6 EAU90399.2 - 0.014 14.8 25.4 0.046 13.1 25.5 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PspA_IM30 PF04012.12 EAU90399.2 - 0.015 14.9 4.0 0.015 14.9 4.0 3.0 1 1 1 2 2 2 0 PspA/IM30 family LPP PF04728.13 EAU90399.2 - 0.015 15.7 4.8 8.6 6.8 0.1 3.8 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF2935 PF11155.8 EAU90399.2 - 0.015 15.6 3.8 2.4 8.5 1.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) BST2 PF16716.5 EAU90399.2 - 0.021 15.4 16.9 0.36 11.4 2.3 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 EAU90399.2 - 0.024 13.5 25.0 0.0095 14.9 19.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 EAU90399.2 - 0.025 12.1 17.7 0.034 11.7 17.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Flagellin_N PF00669.20 EAU90399.2 - 0.034 14.3 1.1 0.034 14.3 1.1 2.8 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region WXG100 PF06013.12 EAU90399.2 - 0.053 13.8 10.6 0.35 11.1 2.3 3.7 1 1 1 3 3 2 0 Proteins of 100 residues with WXG V_ATPase_I PF01496.19 EAU90399.2 - 0.055 11.4 16.7 0.042 11.8 15.4 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin PF00261.20 EAU90399.2 - 0.064 12.6 31.9 0.29 10.5 30.8 2.2 1 1 0 1 1 1 0 Tropomyosin Tropomyosin_1 PF12718.7 EAU90399.2 - 0.086 13.0 29.6 0.051 13.7 21.4 2.5 1 1 1 2 2 2 0 Tropomyosin like Phlebovirus_NSM PF07246.11 EAU90399.2 - 0.12 11.7 13.4 0.18 11.2 13.4 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Allexi_40kDa PF05549.11 EAU90399.2 - 0.16 11.5 10.7 2.6 7.5 4.9 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein CENP-H PF05837.12 EAU90399.2 - 0.21 12.0 24.6 0.68 10.4 10.1 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 EAU90399.2 - 0.26 11.5 23.2 0.52 10.6 10.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ExsD PF16806.5 EAU90399.2 - 0.32 10.9 9.7 0.16 11.9 5.9 1.9 1 1 1 2 2 2 0 Antiactivator protein ExsD Fez1 PF06818.15 EAU90399.2 - 0.37 11.2 28.1 1.6 9.2 28.1 1.9 1 1 0 1 1 1 0 Fez1 Snapin_Pallidin PF14712.6 EAU90399.2 - 0.38 11.2 12.9 2.2 8.8 4.3 3.9 1 1 2 4 4 4 0 Snapin/Pallidin TACC_C PF05010.14 EAU90399.2 - 0.49 10.2 22.8 2.1 8.1 12.6 2.5 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DASH_Spc19 PF08287.11 EAU90399.2 - 0.55 10.1 27.3 0.81 9.6 15.0 2.5 1 1 1 2 2 2 0 Spc19 CENP-K PF11802.8 EAU90399.2 - 0.57 9.7 15.4 0.99 8.9 15.4 1.3 1 0 0 1 1 1 0 Centromere-associated protein K DUF724 PF05266.14 EAU90399.2 - 0.71 9.7 23.2 1.5 8.6 15.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF724) KxDL PF10241.9 EAU90399.2 - 0.76 10.1 14.0 0.21 11.9 6.6 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein Occludin_ELL PF07303.13 EAU90399.2 - 0.87 10.3 15.9 2 9.2 6.4 3.0 1 1 2 3 3 3 0 Occludin homology domain SNARE PF05739.19 EAU90399.2 - 0.94 9.5 3.5 6.3 6.9 0.3 2.9 2 0 0 2 2 2 0 SNARE domain DUF4407 PF14362.6 EAU90399.2 - 1 8.6 23.0 0.11 11.8 15.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4795 PF16043.5 EAU90399.2 - 1.1 8.9 19.1 2 8.0 19.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) zf-C4H2 PF10146.9 EAU90399.2 - 1.1 9.5 17.4 0.58 10.4 13.1 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein PRKG1_interact PF15898.5 EAU90399.2 - 2.3 9.2 27.3 0.7 10.8 9.6 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain COG2 PF06148.11 EAU90399.2 - 2.4 8.3 16.1 2.4 8.3 7.1 3.2 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Swi5 PF07061.11 EAU90399.2 - 3 8.0 19.3 3.6 7.7 3.9 3.9 2 1 2 4 4 4 0 Swi5 Atg14 PF10186.9 EAU90399.2 - 3.3 6.7 26.0 0.98 8.4 13.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DASH_Spc34 PF08657.10 EAU90399.2 - 3.3 7.4 16.4 2.9 7.6 12.5 2.4 2 1 1 3 3 3 0 DASH complex subunit Spc34 IFT57 PF10498.9 EAU90399.2 - 3.5 6.5 19.3 1.3 8.0 14.0 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CCDC-167 PF15188.6 EAU90399.2 - 3.5 8.0 20.0 0.25 11.7 10.8 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 TMPIT PF07851.13 EAU90399.2 - 4.3 6.5 17.4 1.8 7.7 12.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein PIN_8 PF18476.1 EAU90399.2 - 5.6 6.7 15.4 9.3 6.0 13.2 2.0 1 1 1 2 2 2 0 PIN like domain DUF745 PF05335.13 EAU90399.2 - 6.2 6.5 21.4 0.18 11.5 11.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Jnk-SapK_ap_N PF09744.9 EAU90399.2 - 6.2 7.0 29.8 7.8 6.7 17.0 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF87 PF01935.17 EAU90399.2 - 6.6 6.7 8.4 19 5.3 8.4 1.8 1 1 0 1 1 1 0 Helicase HerA, central domain LMBR1 PF04791.16 EAU90399.2 - 6.8 5.5 10.9 8.1 5.2 10.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_S PF02609.16 EAU90399.2 - 7.4 6.7 10.6 17 5.6 0.9 3.9 4 0 0 4 4 4 0 Exonuclease VII small subunit CENP-F_leu_zip PF10473.9 EAU90399.2 - 7.5 6.6 27.5 4.7 7.2 20.0 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 EAU90399.2 - 9.5 6.6 26.5 2.4 8.5 7.2 2.9 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C3HC4_3 PF13920.6 EAU90400.2 - 3.1e-09 36.6 5.1 4.5e-09 36.0 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU90400.2 - 5e-09 36.4 5.9 7.8e-09 35.7 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU90400.2 - 5e-09 36.0 5.7 5.9e-09 35.8 3.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAU90400.2 - 1.8e-08 34.1 6.2 2.9e-08 33.4 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU90400.2 - 2.5e-08 33.9 8.0 4.1e-08 33.2 8.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAU90400.2 - 1.7e-06 27.9 6.9 2.8e-06 27.2 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EAU90400.2 - 1.1e-05 25.2 8.2 2.7e-05 23.9 8.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU90400.2 - 0.00029 20.6 6.3 0.00053 19.8 6.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EAU90400.2 - 0.0093 15.7 3.6 0.025 14.3 3.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger Leu_zip PF15294.6 EAU90400.2 - 0.016 14.7 12.0 0.022 14.3 12.0 1.2 1 0 0 1 1 1 0 Leucine zipper DUF1664 PF07889.12 EAU90400.2 - 0.041 13.9 1.1 0.041 13.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 EAU90400.2 - 0.048 14.0 10.2 0.28 11.6 1.5 2.4 1 1 1 2 2 2 0 Syntaxin-like protein zf-rbx1 PF12678.7 EAU90400.2 - 0.053 13.8 4.8 0.44 10.9 4.8 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain DUF2594 PF10769.9 EAU90400.2 - 0.071 13.1 0.0 0.74 9.9 0.0 2.4 3 0 0 3 3 2 0 Protein of unknown function (DUF2594) zf-RING_4 PF14570.6 EAU90400.2 - 0.21 11.4 6.0 0.47 10.3 6.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Dor1 PF04124.12 EAU90400.2 - 0.54 8.9 11.4 4 6.0 11.2 2.1 1 1 0 1 1 1 0 Dor1-like family zf-ANAPC11 PF12861.7 EAU90400.2 - 0.6 10.2 3.3 1.8 8.7 3.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4407 PF14362.6 EAU90400.2 - 0.81 9.0 13.3 1.2 8.4 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EAU90400.2 - 1.1 8.3 12.7 23 3.9 12.7 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EAU90400.2 - 2.3 8.4 7.2 2.2 8.4 4.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IBR PF01485.21 EAU90400.2 - 3.1 8.1 6.0 4.6 7.6 2.8 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain FapA PF03961.13 EAU90400.2 - 5.1 5.6 8.5 0.49 8.9 1.8 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 EAU90400.2 - 5.3 4.8 8.0 7.2 4.4 8.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EAU90400.2 - 6.2 7.5 15.2 10 6.9 4.8 2.8 1 1 2 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 EAU90400.2 - 7.3 6.6 23.0 0.14 12.2 8.9 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 EAU90400.2 - 7.5 6.9 9.7 1.8 8.9 0.3 2.7 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 EAU90400.2 - 8.7 5.9 12.5 3.5 7.2 1.6 2.4 1 1 1 2 2 2 0 fzo-like conserved region Cep57_MT_bd PF06657.13 EAU90400.2 - 10 6.7 17.1 7 7.2 0.9 3.4 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 zf-C3HC4_3 PF13920.6 EAU90401.1 - 7.9e-10 38.5 4.2 1.7e-09 37.3 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU90401.1 - 1.3e-09 38.0 8.5 2.5e-09 37.2 8.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAU90401.1 - 3.9e-09 36.4 3.8 3.9e-09 36.4 3.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAU90401.1 - 4.1e-08 33.1 6.0 8.7e-08 32.0 6.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EAU90401.1 - 5.4e-08 33.0 5.4 1.1e-07 32.1 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAU90401.1 - 1.8e-07 30.9 6.8 3.6e-07 29.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU90401.1 - 4.7e-07 29.6 5.3 9.5e-07 28.6 5.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAU90401.1 - 3.5e-05 23.6 7.6 0.00013 21.7 7.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU90401.1 - 0.0044 17.3 2.7 0.016 15.5 2.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAU90401.1 - 0.006 16.3 3.5 0.018 14.8 3.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EAU90401.1 - 0.019 15.0 1.7 0.032 14.3 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HALZ PF02183.18 EAU90401.1 - 0.028 14.6 4.7 0.028 14.6 4.7 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Zip PF02535.22 EAU90401.1 - 0.056 12.7 0.2 0.065 12.4 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SnoaL PF07366.12 EAU90401.1 - 0.087 12.6 0.3 0.35 10.7 0.0 2.0 2 1 0 2 2 2 0 SnoaL-like polyketide cyclase zf-RING_4 PF14570.6 EAU90401.1 - 0.16 11.8 7.3 0.68 9.8 7.4 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ATPase PF06745.13 EAU90401.1 - 0.22 10.9 1.7 0.28 10.5 1.5 1.3 1 1 0 1 1 1 0 KaiC TPR_MLP1_2 PF07926.12 EAU90401.1 - 0.6 10.2 33.6 0.35 11.0 17.3 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EAU90401.1 - 1.4 8.4 16.5 1.8 8.0 16.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GvpL_GvpF PF06386.11 EAU90401.1 - 1.5 8.7 20.5 3 7.7 20.4 1.6 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1664 PF07889.12 EAU90401.1 - 2.1 8.4 7.1 1.8 8.6 5.0 1.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) zf-RING_6 PF14835.6 EAU90401.1 - 2.6 8.0 5.3 6.1 6.8 5.3 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein LMBR1 PF04791.16 EAU90401.1 - 2.7 6.8 4.1 3.1 6.6 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein G-gamma PF00631.22 EAU90401.1 - 5.6 7.0 8.8 0.16 12.0 1.4 2.4 2 1 0 2 2 2 0 GGL domain YabA PF06156.13 EAU90401.1 - 8.9 7.0 15.3 2.6 8.7 10.1 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 EAU90401.1 - 9 5.3 19.7 22 4.0 19.7 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_UBOX PF13445.6 EAU90402.2 - 1.6e-09 37.6 7.6 1.7e-09 37.6 6.5 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAU90402.2 - 1.4e-08 34.4 7.2 2.6e-08 33.6 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU90402.2 - 2.7e-08 33.5 10.0 4.7e-08 32.8 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU90402.2 - 1.1e-07 32.1 10.4 1.8e-07 31.4 10.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EAU90402.2 - 2.4e-07 30.8 13.0 4.3e-07 30.0 13.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TPR_MLP1_2 PF07926.12 EAU90402.2 - 5.7e-06 26.4 24.0 5.7e-06 26.4 24.0 2.4 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein zf-RING_5 PF14634.6 EAU90402.2 - 2.7e-05 24.0 10.3 4.7e-05 23.3 10.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Macoilin PF09726.9 EAU90402.2 - 4.3e-05 22.3 5.9 7.2e-05 21.6 5.9 1.4 1 0 0 1 1 1 1 Macoilin family zf-C3HC4_2 PF13923.6 EAU90402.2 - 4.5e-05 23.2 12.4 0.00012 21.9 12.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU90402.2 - 0.0011 18.8 9.3 0.0021 17.9 9.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Syntaxin_2 PF14523.6 EAU90402.2 - 0.0045 17.3 1.1 0.0045 17.3 1.1 2.3 1 1 1 2 2 2 1 Syntaxin-like protein YabA PF06156.13 EAU90402.2 - 0.007 17.0 2.3 0.007 17.0 2.3 3.3 1 1 2 3 3 3 1 Initiation control protein YabA HAP1_N PF04849.13 EAU90402.2 - 0.0087 15.3 16.8 0.0087 15.3 16.8 2.1 1 1 1 2 2 2 1 HAP1 N-terminal conserved region zf-RING_11 PF17123.5 EAU90402.2 - 0.0095 15.7 8.0 0.014 15.1 6.9 1.9 1 1 1 2 2 2 1 RING-like zinc finger GAS PF13851.6 EAU90402.2 - 0.012 14.9 13.3 0.012 14.9 13.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nup54 PF13874.6 EAU90402.2 - 0.034 14.3 14.4 0.03 14.4 11.8 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.8 EAU90402.2 - 0.048 13.8 26.7 0.026 14.6 10.9 2.5 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding ApoO PF09769.9 EAU90402.2 - 0.086 12.8 8.1 0.16 11.9 0.2 2.8 1 1 2 3 3 3 0 Apolipoprotein O zf-rbx1 PF12678.7 EAU90402.2 - 0.14 12.5 6.3 0.32 11.3 6.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Sulfatase_C PF14707.6 EAU90402.2 - 0.25 12.1 4.5 3.2 8.5 0.0 3.2 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase Spc7 PF08317.11 EAU90402.2 - 0.35 9.7 27.6 0.45 9.3 24.5 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 EAU90402.2 - 0.4 11.1 12.5 3.6 8.1 0.5 3.5 3 1 0 3 3 3 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.19 EAU90402.2 - 0.41 8.5 11.4 0.56 8.1 11.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_6 PF14835.6 EAU90402.2 - 0.46 10.4 6.4 1 9.3 6.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rootletin PF15035.6 EAU90402.2 - 0.46 10.5 23.1 0.88 9.6 22.6 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.21 EAU90402.2 - 0.48 10.6 20.6 1.6 8.9 2.9 3.8 2 1 1 3 3 3 0 bZIP transcription factor DUF4201 PF13870.6 EAU90402.2 - 0.56 9.9 26.1 0.18 11.5 18.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 EAU90402.2 - 0.59 9.4 23.3 0.44 9.8 1.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Cas_DxTHG PF09455.10 EAU90402.2 - 0.6 9.6 6.0 0.78 9.3 6.0 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family CENP-F_leu_zip PF10473.9 EAU90402.2 - 0.71 9.9 28.9 5.4 7.0 15.0 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-RING_4 PF14570.6 EAU90402.2 - 0.75 9.6 7.3 1.8 8.4 7.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Scaffolding_pro PF11418.8 EAU90402.2 - 0.79 10.3 5.8 0.92 10.1 1.9 2.7 1 1 2 3 3 3 0 Phi29 scaffolding protein Prp19 PF08606.11 EAU90402.2 - 0.8 9.7 7.8 2.4 8.2 1.3 3.1 1 1 1 2 2 2 0 Prp19/Pso4-like Exonuc_VII_L PF02601.15 EAU90402.2 - 0.82 9.2 12.5 1.3 8.5 12.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DOG1 PF14144.6 EAU90402.2 - 0.9 9.8 3.5 11 6.3 0.1 2.7 1 1 1 2 2 2 0 Seed dormancy control Atg14 PF10186.9 EAU90402.2 - 0.97 8.5 20.6 16 4.5 20.6 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Hormone_1 PF00103.20 EAU90402.2 - 1 9.1 5.9 12 5.6 1.7 2.2 2 0 0 2 2 2 0 Somatotropin hormone family Mod_r PF07200.13 EAU90402.2 - 1.3 9.1 22.5 5.5 7.1 11.5 2.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FYVE PF01363.21 EAU90402.2 - 1.3 9.2 5.4 4.3 7.5 5.4 1.8 1 1 0 1 1 1 0 FYVE zinc finger HALZ PF02183.18 EAU90402.2 - 1.4 9.2 27.4 0.087 13.1 7.0 4.2 4 0 0 4 4 3 0 Homeobox associated leucine zipper DUF948 PF06103.11 EAU90402.2 - 1.5 9.1 5.5 21 5.4 0.2 2.8 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 EAU90402.2 - 1.5 7.6 7.3 2.2 7.1 7.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Bap31_Bap29_C PF18035.1 EAU90402.2 - 1.7 8.7 21.4 0.69 10.0 8.3 3.9 2 1 2 4 4 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain COG6 PF06419.11 EAU90402.2 - 1.7 6.7 13.8 0.19 9.9 1.4 2.2 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 TolA_bind_tri PF16331.5 EAU90402.2 - 2.1 8.5 19.0 0.087 12.9 1.6 3.6 1 1 2 3 3 2 0 TolA binding protein trimerisation Baculo_F PF12259.8 EAU90402.2 - 2.2 6.7 9.0 0.1 11.1 1.8 1.8 1 1 1 2 2 2 0 Baculovirus F protein Laminin_II PF06009.12 EAU90402.2 - 2.3 8.2 13.2 2 8.4 5.3 2.3 1 1 1 2 2 2 0 Laminin Domain II IBR PF01485.21 EAU90402.2 - 2.6 8.3 7.1 14 6.0 7.0 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain MPS2 PF17060.5 EAU90402.2 - 2.9 7.1 15.4 28 3.8 15.4 2.0 1 1 0 1 1 1 0 Monopolar spindle protein 2 EzrA PF06160.12 EAU90402.2 - 3.3 5.8 22.6 0.24 9.5 1.5 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA GrpE PF01025.19 EAU90402.2 - 3.6 7.2 26.5 2.5 7.7 9.3 3.2 1 1 1 2 2 2 0 GrpE Presenilin PF01080.17 EAU90402.2 - 4.4 6.0 5.5 7.6 5.2 5.5 1.4 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EAU90402.2 - 4.9 6.4 25.1 0.83 8.9 9.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) KxDL PF10241.9 EAU90402.2 - 5.1 7.4 11.8 1.9 8.8 3.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein bZIP_Maf PF03131.17 EAU90402.2 - 5.3 7.6 25.0 0.7 10.5 7.7 3.5 2 1 0 3 3 3 0 bZIP Maf transcription factor HOOK PF05622.12 EAU90402.2 - 5.5 5.0 26.1 15 3.6 26.1 1.6 1 1 0 1 1 1 0 HOOK protein DUF1664 PF07889.12 EAU90402.2 - 7.7 6.6 11.2 28 4.8 6.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) I_LWEQ PF01608.17 EAU90402.2 - 8.6 6.6 15.0 1.8 8.8 10.7 1.9 1 1 1 2 2 2 0 I/LWEQ domain FTA4 PF13093.6 EAU90402.2 - 8.8 6.2 19.2 0.45 10.4 11.2 2.5 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 NAD_binding_10 PF13460.6 EAU90403.1 - 1.5e-06 28.2 0.0 2.1e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAU90403.1 - 7e-05 22.4 0.0 9.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EAU90403.1 - 0.00027 21.3 0.0 0.00071 20.0 0.0 1.7 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EAU90403.1 - 0.13 11.4 0.2 10 5.2 0.2 2.2 1 1 0 2 2 2 0 Male sterility protein NMO PF03060.15 EAU90404.1 - 4.3e-45 154.6 0.1 6.3e-45 154.0 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EAU90404.1 - 6.7e-09 35.2 0.3 5.5e-07 28.9 0.3 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EAU90404.1 - 0.001 18.2 2.5 0.0017 17.5 2.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ATG16 PF08614.11 EAU90405.2 - 0.011 15.9 4.0 0.011 15.9 4.0 3.7 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) TACC_C PF05010.14 EAU90405.2 - 0.011 15.5 12.8 0.011 15.5 12.8 3.2 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Stealth_CR3 PF17102.5 EAU90405.2 - 0.68 9.9 5.1 17 5.4 0.3 3.6 3 0 0 3 3 3 0 Stealth protein CR3, conserved region 3 Fez1 PF06818.15 EAU90405.2 - 1 9.8 51.6 0.078 13.4 26.4 2.7 2 1 1 3 3 3 0 Fez1 COG5 PF10392.9 EAU90405.2 - 5.4 7.2 22.6 2.1 8.5 2.0 4.0 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Sulfatase_C PF14707.6 EAU90405.2 - 7.5 7.3 10.0 2 9.1 0.4 3.8 1 1 3 4 4 4 0 C-terminal region of aryl-sulfatase p450 PF00067.22 EAU90406.2 - 7.7e-53 179.9 0.0 1e-52 179.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RhoGEF PF00621.20 EAU90407.2 - 1.7e-64 217.4 4.4 5.5e-36 124.5 1.5 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 EAU90407.2 - 7.5e-57 193.0 0.0 1.2e-56 192.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EAU90407.2 - 2.1e-11 44.1 0.0 4.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 EAU90407.2 - 0.015 15.3 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 EAU90407.2 - 0.037 14.6 0.0 0.089 13.3 0.0 1.7 1 0 0 1 1 1 0 PH domain BicD PF09730.9 EAU90407.2 - 0.26 9.6 0.0 0.37 9.1 0.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Methyltransf_12 PF08242.12 EAU90408.1 - 6.4e-13 49.3 0.0 2.1e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU90408.1 - 2.5e-12 47.3 0.0 7.1e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU90408.1 - 8.2e-11 42.0 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU90408.1 - 1.9e-09 38.1 0.0 7.1e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU90408.1 - 3.7e-07 30.0 0.0 7.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EAU90408.1 - 0.00018 22.5 0.0 0.00094 20.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EAU90408.1 - 0.0015 18.4 0.0 0.88 9.4 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 EAU90408.1 - 0.0046 16.2 0.0 0.012 14.9 0.0 1.5 1 1 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 EAU90408.1 - 0.007 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 EAU90408.1 - 0.039 13.4 0.0 9.5 5.6 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 EAU90408.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 EAU90409.1 - 0.013 15.4 0.9 0.033 14.1 0.4 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EAU90409.1 - 0.061 13.2 6.2 0.23 11.4 1.5 3.7 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 EAU90410.2 - 4.1e-07 29.8 5.8 2.3e-06 27.4 5.8 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90410.2 - 0.27 11.2 5.7 27 4.8 0.0 4.1 4 0 0 4 4 4 0 F-box domain Amidase PF01425.21 EAU90414.1 - 3.6e-122 408.6 0.1 4.6e-122 408.2 0.1 1.1 1 0 0 1 1 1 1 Amidase WD40 PF00400.32 EAU90415.2 - 1.5e-18 66.8 3.0 1.6e-05 25.5 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU90415.2 - 3.2e-06 27.3 0.3 0.036 14.4 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_Rpc4 PF05132.14 EAU90415.2 - 0.0036 17.7 3.0 0.22 12.0 0.8 2.3 2 0 0 2 2 2 2 RNA polymerase III RPC4 WD40_like PF17005.5 EAU90415.2 - 0.083 12.2 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 EAU90415.2 - 0.11 11.0 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF1604 PF07713.13 EAU90416.1 - 1.2e-40 137.2 0.4 1.2e-40 137.2 0.4 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EAU90416.1 - 4.7e-08 32.8 0.3 9.7e-07 28.6 0.1 2.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EAU90416.1 - 0.084 13.0 0.1 0.084 13.0 0.1 4.6 5 0 0 5 5 5 0 G-patch domain TFIIF_alpha PF05793.12 EAU90416.1 - 4.3 5.8 24.7 0.058 12.0 16.4 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Uds1 PF15456.6 EAU90417.1 - 0.052 13.7 5.6 0.32 11.2 0.9 3.0 1 1 1 2 2 2 0 Up-regulated During Septation DUF4686 PF15742.5 EAU90417.1 - 0.14 11.2 2.8 0.23 10.5 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DivIC PF04977.15 EAU90417.1 - 0.19 11.5 0.4 0.54 10.1 0.4 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF948 PF06103.11 EAU90417.1 - 0.7 10.2 3.3 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MFS_1 PF07690.16 EAU90418.2 - 1.5e-22 80.1 22.1 1.5e-22 80.1 22.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PACT_coil_coil PF10495.9 EAU90419.2 - 3.4e-17 62.8 0.0 3.4e-17 62.8 0.0 6.1 6 2 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein HMMR_N PF15905.5 EAU90419.2 - 2.5e-05 23.9 28.5 2.5e-05 23.9 28.5 8.1 3 2 5 9 9 9 2 Hyaluronan mediated motility receptor N-terminal SlyX PF04102.12 EAU90419.2 - 0.00089 19.8 5.7 0.00089 19.8 5.7 15.4 4 3 9 15 15 15 2 SlyX ZapB PF06005.12 EAU90419.2 - 0.00094 19.6 6.3 0.00094 19.6 6.3 16.4 7 4 7 14 14 14 3 Cell division protein ZapB Lebercilin PF15619.6 EAU90419.2 - 0.0018 18.0 17.2 0.0018 18.0 17.2 10.2 3 3 6 9 9 9 2 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 EAU90419.2 - 0.0019 18.7 24.6 0.0019 18.7 24.6 7.5 2 2 5 7 7 7 2 Fez1 DUF812 PF05667.11 EAU90419.2 - 0.0032 16.4 20.5 0.0032 16.4 20.5 7.1 3 2 3 7 7 7 4 Protein of unknown function (DUF812) Fib_alpha PF08702.10 EAU90419.2 - 0.01 16.0 3.4 0.01 16.0 3.4 9.9 4 2 6 10 10 10 0 Fibrinogen alpha/beta chain family DUF5340 PF17275.2 EAU90419.2 - 0.093 12.9 0.0 0.093 12.9 0.0 4.9 4 1 0 4 4 4 0 Family of unknown function (DUF5340) Aurora-A_bind PF09041.10 EAU90419.2 - 3.8 7.6 5.3 0.72 10.0 0.2 2.5 2 0 0 2 2 2 0 Aurora-A binding PGA2 PF07543.12 EAU90420.1 - 0.034 14.1 2.0 0.065 13.2 2.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Cwf_Cwc_15 PF04889.12 EAU90420.1 - 1.3 8.7 8.0 1.9 8.2 8.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EAU90420.1 - 2.8 7.2 6.8 4.1 6.6 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein KH_1 PF00013.29 EAU90423.2 - 1.6e-05 24.6 0.1 0.00073 19.3 0.1 2.7 2 0 0 2 2 2 2 KH domain SUR7 PF06687.12 EAU90424.2 - 1.1e-07 31.8 3.0 6.4e-07 29.2 3.0 1.8 1 1 0 1 1 1 1 SUR7/PalI family NicO PF03824.16 EAU90424.2 - 0.013 14.8 1.8 0.024 14.0 1.8 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF1752 PF08550.10 EAU90425.2 - 1.4e-08 34.4 9.4 3e-08 33.3 9.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF5081 PF16887.5 EAU90427.1 - 0.23 10.5 0.1 0.37 9.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) RhoGEF PF00621.20 EAU90429.2 - 7.7e-67 225.1 7.8 3e-34 118.8 0.1 2.7 3 0 0 3 3 3 2 RhoGEF domain CNH PF00780.22 EAU90429.2 - 8.4e-64 215.8 0.0 1.3e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EAU90429.2 - 5.3e-16 58.9 0.2 1.3e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EAU90429.2 - 0.0024 18.4 0.0 0.019 15.5 0.0 2.5 1 1 0 1 1 1 1 PH domain DEP PF00610.21 EAU90429.2 - 0.0025 17.8 1.5 0.0056 16.7 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_16 PF17838.1 EAU90429.2 - 0.058 13.2 0.0 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 PH domain UBX PF00789.20 EAU90430.1 - 1.4e-12 47.6 0.3 6.7e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 UBX domain UBA PF00627.31 EAU90430.1 - 8.6e-06 25.5 0.0 2.5e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain DUF572 PF04502.13 EAU90430.1 - 0.023 14.3 15.0 0.035 13.7 15.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C2H2_2 PF12756.7 EAU90430.1 - 0.12 12.7 3.3 0.14 12.5 0.5 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Med26_C PF15693.5 EAU90430.1 - 0.52 10.4 6.6 0.85 9.7 6.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal F-box-like PF12937.7 EAU90432.2 - 1.6e-05 24.7 1.5 3.2e-05 23.7 1.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90432.2 - 0.0011 18.8 1.2 0.0024 17.7 1.2 1.6 1 0 0 1 1 1 1 F-box domain BIR PF00653.21 EAU90433.2 - 3.1e-35 120.7 5.5 8e-18 64.9 0.3 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 EAU90433.2 - 4.3e-05 23.6 0.1 0.019 15.0 0.0 2.6 2 0 0 2 2 2 2 C3HC zinc finger-like zf-BED PF02892.15 EAU90433.2 - 0.08 13.0 0.2 23 5.1 0.0 2.8 3 0 0 3 3 3 0 BED zinc finger WAPL PF07814.13 EAU90434.2 - 3.5e-08 32.6 2.1 2.1e-05 23.5 0.0 3.9 3 1 1 4 4 4 3 Wings apart-like protein regulation of heterochromatin Peptidase_C15 PF01470.17 EAU90435.2 - 0.00029 21.1 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 Pyroglutamyl peptidase BCS1_N PF08740.11 EAU90436.2 - 2.6e-41 141.7 0.9 4.7e-41 140.8 0.9 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EAU90436.2 - 3.8e-19 69.4 0.0 9.1e-19 68.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU90436.2 - 0.00031 21.2 0.0 0.00078 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EAU90436.2 - 0.0054 16.5 0.0 0.0093 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 EAU90436.2 - 0.0072 16.1 0.1 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAU90436.2 - 0.014 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 EAU90436.2 - 0.025 13.5 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF815 PF05673.13 EAU90436.2 - 0.026 13.7 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EAU90436.2 - 0.033 14.7 0.0 0.11 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EAU90436.2 - 0.037 14.2 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU90436.2 - 0.04 13.4 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EAU90436.2 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.13 EAU90436.2 - 0.068 12.4 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 EAU90436.2 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 EAU90436.2 - 0.12 12.6 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU90436.2 - 0.18 12.1 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EAU90436.2 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pantoate_ligase PF02569.15 EAU90437.2 - 5.6e-94 314.3 0.0 6.4e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ribonuc_P_40 PF08584.11 EAU90442.2 - 2.7e-31 108.9 0.0 2.3e-20 73.1 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit HMG_CoA_synt_C PF08540.10 EAU90443.1 - 3.7e-90 302.4 0.1 4.5e-90 302.1 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EAU90443.1 - 1.4e-84 282.3 0.2 2e-84 281.8 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.10 EAU90443.1 - 0.022 14.6 0.1 0.22 11.4 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3641 PF12345.8 EAU90443.1 - 0.17 11.9 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) DUF3455 PF11937.8 EAU90444.1 - 4.3e-21 76.0 0.0 5.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_23 PF13489.6 EAU90445.1 - 1.7e-23 83.3 0.0 2.7e-23 82.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU90445.1 - 2e-17 63.6 0.0 4e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU90445.1 - 1.7e-14 54.4 0.0 3.9e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU90445.1 - 1.6e-13 51.2 0.0 4.5e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU90445.1 - 3.7e-11 43.0 0.0 9.5e-11 41.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAU90445.1 - 2.3e-07 30.4 0.0 0.017 14.4 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EAU90445.1 - 0.0001 21.8 0.0 0.0002 20.9 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EAU90445.1 - 0.0047 16.5 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TehB PF03848.14 EAU90445.1 - 0.0086 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 EAU90445.1 - 0.025 14.6 0.1 0.052 13.5 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EAU90445.1 - 0.026 13.4 0.0 0.16 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 EAU90445.1 - 0.027 14.1 0.3 0.063 12.9 0.1 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW TPMT PF05724.11 EAU90445.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) E1-E2_ATPase PF00122.20 EAU90446.1 - 6.7e-51 172.4 3.3 6.7e-51 172.4 3.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EAU90446.1 - 3.6e-31 109.1 0.7 8.7e-31 107.9 0.7 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EAU90446.1 - 7.1e-29 100.0 0.1 5e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EAU90446.1 - 0.00016 21.5 1.7 0.00076 19.3 0.6 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Otopetrin PF03189.13 EAU90446.1 - 0.11 11.3 1.4 0.3 9.9 1.6 1.5 1 1 0 1 1 1 0 Otopetrin DUF1980 PF09323.10 EAU90446.1 - 0.35 10.8 3.1 0.43 10.5 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) DUF1656 PF07869.12 EAU90446.1 - 2.6 8.1 9.1 2.2 8.3 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Dynactin_p22 PF07426.11 EAU90447.2 - 2.1e-16 60.2 0.5 4e-14 52.8 0.5 2.4 2 1 0 2 2 2 2 Dynactin subunit p22 Lebercilin PF15619.6 EAU90447.2 - 0.021 14.5 1.7 0.021 14.5 1.7 1.7 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3879 PF12995.7 EAU90447.2 - 0.09 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) PH_10 PF15411.6 EAU90449.2 - 4.8e-24 85.0 0.0 8.3e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EAU90449.2 - 6.5e-06 26.5 0.1 3.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-RING_UBOX PF13445.6 EAU90449.2 - 0.0001 22.2 1.3 0.00025 21.0 1.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAU90449.2 - 0.00014 22.1 1.7 0.00032 21.0 1.8 1.6 1 1 0 1 1 1 1 Ring finger domain VWA_3 PF13768.6 EAU90449.2 - 0.00016 21.7 0.2 0.00086 19.3 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 EAU90449.2 - 0.0022 17.9 0.5 0.0045 16.9 0.5 1.5 1 1 0 1 1 1 1 zinc-RING finger domain Phage_lysozyme PF00959.19 EAU90449.2 - 0.1 13.0 0.2 18 5.8 0.0 3.4 4 0 0 4 4 4 0 Phage lysozyme zf-C3HC4 PF00097.25 EAU90449.2 - 0.11 12.4 1.0 0.23 11.4 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAU90449.2 - 0.33 10.7 4.2 0.27 11.0 2.1 2.0 2 0 0 2 2 2 0 RING-like zinc finger Prok-RING_1 PF14446.6 EAU90449.2 - 0.45 10.5 1.8 0.75 9.8 0.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PMT PF02366.18 EAU90450.1 - 1.6e-79 266.9 20.0 1.6e-79 266.9 20.0 1.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EAU90450.1 - 1e-63 214.6 3.4 1e-63 214.6 3.4 3.2 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EAU90450.1 - 3.7e-18 66.0 3.4 9.4e-18 64.7 1.7 2.0 2 0 0 2 2 2 1 MIR domain PMT_2 PF13231.6 EAU90450.1 - 0.00015 22.0 12.1 0.00015 22.0 12.1 3.0 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PX PF00787.24 EAU90451.2 - 9.6e-16 57.8 0.1 2e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 PX domain DOPA_dioxygen PF08883.11 EAU90452.2 - 8.2e-11 42.0 0.5 1.1e-10 41.6 0.5 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PALP PF00291.25 EAU90453.2 - 3.6e-52 177.6 0.8 4.6e-52 177.3 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRMT5 PF05185.16 EAU90453.2 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DUF2625 PF10946.8 EAU90453.2 - 0.2 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2625 PI3_PI4_kinase PF00454.27 EAU90455.2 - 8.5e-55 186.3 0.0 1.6e-54 185.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EAU90455.2 - 1.2e-28 100.2 0.6 7.5e-28 97.6 0.6 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EAU90455.2 - 8.6e-10 38.3 0.0 2.3e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 FATC domain Pkinase PF00069.25 EAU90456.2 - 1.7e-73 247.2 0.0 2.3e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU90456.2 - 1.4e-47 162.1 0.0 2.3e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EAU90456.2 - 5.5e-23 81.1 0.1 1.3e-22 79.9 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EAU90456.2 - 4.8e-05 22.3 0.0 9.3e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAU90456.2 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAU90456.2 - 0.074 12.4 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BCS1_N PF08740.11 EAU90458.2 - 2.4e-41 141.8 5.2 2.4e-41 141.8 5.2 2.4 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 EAU90458.2 - 6e-17 62.3 0.0 6.4e-16 59.0 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EAU90458.2 - 0.0004 19.6 0.0 0.001 18.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EAU90458.2 - 0.0022 18.4 0.0 0.0022 18.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_5 PF07728.14 EAU90458.2 - 0.0099 15.9 0.0 0.029 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EAU90458.2 - 0.031 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EAU90458.2 - 0.092 13.1 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EAU90458.2 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EAU90458.2 - 0.17 12.5 0.0 0.17 12.5 0.0 4.1 3 1 2 5 5 3 0 AAA domain AAA_6 PF12774.7 EAU90458.2 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region MCM_bind PF09739.9 EAU90458.2 - 2 6.8 20.7 3.1 6.1 20.7 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_11 PF13086.6 EAU90458.2 - 2.8 7.6 0.0 2.8 7.6 0.0 2.8 2 1 0 2 2 1 0 AAA domain GAGA_bind PF06217.12 EAU90458.2 - 4.2 7.6 21.6 8 6.7 21.6 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family CCDC71L PF15374.6 EAU90458.2 - 4.7 6.4 23.8 7.1 5.8 23.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF4407 PF14362.6 EAU90458.2 - 6.5 6.0 21.0 16 4.7 21.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) An_peroxidase PF03098.15 EAU90460.2 - 2.6e-36 125.3 0.0 2.2e-23 82.6 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase GAGE PF05831.11 EAU90460.2 - 0.092 13.3 0.4 0.18 12.3 0.4 1.4 1 0 0 1 1 1 0 GAGE protein PKD_channel PF08016.12 EAU90461.2 - 1.9e-05 23.5 14.3 0.00097 17.9 1.1 2.2 1 1 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 EAU90461.2 - 0.00021 20.6 22.7 0.00021 20.6 22.7 1.9 2 0 0 2 2 2 1 Ion transport protein Ank_2 PF12796.7 EAU90462.2 - 9.8e-12 45.3 0.6 5.7e-05 23.6 0.1 3.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90462.2 - 7.2e-09 36.0 0.2 2.5e-06 27.9 0.1 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90462.2 - 1.1e-08 34.6 0.6 0.01 16.3 0.0 3.9 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.30 EAU90462.2 - 1.1e-06 28.8 2.0 0.0031 17.9 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 EAU90462.2 - 9e-05 22.3 0.2 0.0026 17.6 0.2 2.4 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 EAU90462.2 - 0.00014 22.1 1.1 0.072 13.4 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) USP8_interact PF08941.10 EAU90462.2 - 0.078 12.8 1.4 0.14 11.9 1.4 1.4 1 0 0 1 1 1 0 USP8 interacting Filament PF00038.21 EAU90462.2 - 0.091 12.3 2.8 0.15 11.6 2.8 1.3 1 0 0 1 1 1 0 Intermediate filament protein MAD PF05557.13 EAU90462.2 - 0.095 11.1 1.0 0.14 10.5 1.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein OmpH PF03938.14 EAU90462.2 - 0.22 11.9 5.5 0.4 11.0 5.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Golgin_A5 PF09787.9 EAU90462.2 - 0.48 9.9 3.3 0.76 9.2 3.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 WD40 PF00400.32 EAU90463.1 - 7.2e-41 137.4 9.4 1.1e-07 32.4 0.4 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU90463.1 - 1.8e-15 57.0 0.1 0.045 14.1 0.0 6.0 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EAU90463.1 - 3.4e-13 48.9 1.0 6.6e-13 48.0 1.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 EAU90463.1 - 5.7e-05 22.2 0.1 3.4 6.5 0.0 4.5 2 1 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EAU90463.1 - 0.00061 19.2 0.1 5.5 6.2 0.0 3.6 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EAU90463.1 - 0.001 18.4 0.0 0.57 9.5 0.0 3.8 4 1 1 5 5 5 1 WD40-like domain Nup160 PF11715.8 EAU90463.1 - 1.7 7.2 6.8 6.1 5.4 0.4 3.9 2 1 4 6 6 6 0 Nucleoporin Nup120/160 zf-CCCH PF00642.24 EAU90465.2 - 2.7e-08 33.5 18.9 0.00039 20.3 1.0 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EAU90465.2 - 0.096 12.9 10.7 0.89 9.8 1.5 3.5 2 1 2 4 4 4 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 EAU90465.2 - 0.56 10.4 29.5 0.94 9.6 1.2 5.6 6 0 0 6 6 6 0 Zinc finger domain DnaJ-X PF14308.6 EAU90466.1 - 4.5e-63 212.5 0.0 4.5e-63 212.5 0.0 2.7 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EAU90466.1 - 3.8e-25 87.8 2.4 9.8e-25 86.5 2.4 1.8 1 0 0 1 1 1 1 DnaJ domain FAM199X PF15814.5 EAU90466.1 - 0.0083 15.2 5.2 0.013 14.6 5.2 1.2 1 0 0 1 1 1 1 Protein family FAM199X Hamartin PF04388.12 EAU90466.1 - 1 8.0 6.0 1.6 7.3 6.0 1.3 1 0 0 1 1 1 0 Hamartin protein Peptidase_M20 PF01546.28 EAU90467.2 - 4.8e-08 33.0 0.0 1.2e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EAU90467.2 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.25 EAU90468.2 - 1.3e-65 221.4 0.0 1.8e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU90468.2 - 5.4e-49 166.8 0.0 7.7e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 EAU90468.2 - 5e-07 29.5 2.8 8.8e-07 28.7 2.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 EAU90468.2 - 3.1e-05 23.5 2.6 6.8e-05 22.4 2.6 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type CH PF00307.31 EAU90468.2 - 0.0014 18.8 0.0 0.0036 17.5 0.0 1.7 1 1 0 1 1 1 1 Calponin homology (CH) domain Pkinase_fungal PF17667.1 EAU90468.2 - 0.086 11.6 0.0 0.21 10.3 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EAU90468.2 - 0.1 11.9 0.0 0.69 9.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 EAU90468.2 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EAU90468.2 - 0.19 10.7 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EAU90468.2 - 0.23 11.0 0.1 0.39 10.2 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PHD PF00628.29 EAU90468.2 - 0.78 9.7 4.3 1.7 8.6 4.3 1.5 1 0 0 1 1 1 0 PHD-finger TFIIS_M PF07500.14 EAU90469.1 - 1.9e-18 67.0 0.6 3.5e-18 66.1 0.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EAU90469.1 - 5.3e-15 55.6 0.0 1.4e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 EAU90469.1 - 1.9e-07 30.8 9.8 3.4e-07 30.1 9.8 1.4 1 0 0 1 1 1 1 PHD-finger DUF4196 PF13846.6 EAU90469.1 - 0.0076 16.4 3.3 0.0076 16.4 3.3 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4196) PHD_2 PF13831.6 EAU90469.1 - 4.1 7.1 5.9 6.7 6.4 5.9 1.4 1 0 0 1 1 1 0 PHD-finger ADH_N PF08240.12 EAU90470.2 - 2.2e-19 69.3 1.2 3.8e-19 68.6 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EAU90470.2 - 1.5e-17 63.8 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EAU90470.2 - 4.8e-08 32.7 0.1 5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EAU90470.2 - 0.091 13.8 0.0 0.19 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 EAU90471.2 - 3.2e-58 197.2 0.0 4.4e-57 193.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU90471.2 - 1.3e-23 83.7 0.5 1.7e-18 66.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EAU90471.2 - 1e-05 24.6 0.1 2e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAU90471.2 - 0.0046 16.3 0.6 0.016 14.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU90471.2 - 0.0054 16.7 0.6 0.22 11.4 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU90471.2 - 0.0076 15.6 0.7 0.035 13.4 0.1 2.3 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAU90471.2 - 0.011 14.8 0.1 0.023 13.8 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EAU90471.2 - 0.024 13.4 0.5 0.038 12.8 0.5 1.4 1 1 0 1 1 1 0 Fungal protein kinase DUF1712 PF08217.11 EAU90472.2 - 1e-18 67.2 0.0 1.7e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) PRIMA1 PF16101.5 EAU90472.2 - 7.3 6.6 10.5 0.48 10.5 4.7 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UCH PF00443.29 EAU90473.2 - 3.4e-69 233.2 0.0 5.2e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EAU90473.2 - 4.5e-15 56.0 0.0 1.2e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EAU90473.2 - 2.5e-13 50.3 0.0 6.8e-06 25.9 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EAU90473.2 - 0.0049 16.6 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal Dak1 PF02733.17 EAU90474.2 - 5.1e-108 360.6 0.1 7.4e-108 360.1 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EAU90474.2 - 1.8e-45 155.0 0.3 2.9e-45 154.3 0.3 1.3 1 0 0 1 1 1 1 DAK2 domain Sugar_tr PF00083.24 EAU90475.1 - 1.2e-138 462.8 18.9 1.4e-138 462.6 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EAU90475.1 - 1.1e-21 77.2 26.2 1.1e-21 77.2 26.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyto_heme_lyase PF01265.17 EAU90476.1 - 2.4e-83 280.1 9.8 8.9e-82 274.9 9.8 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Tim44 PF04280.15 EAU90477.1 - 2e-37 128.5 0.6 2e-37 128.5 0.6 1.9 2 0 0 2 2 2 1 Tim44-like domain CENP-O PF09496.10 EAU90477.1 - 0.0089 16.0 1.6 0.014 15.4 0.5 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DMPK_coil PF08826.10 EAU90477.1 - 0.028 14.5 0.2 0.028 14.5 0.2 2.7 3 0 0 3 3 3 0 DMPK coiled coil domain like BORCS7 PF16088.5 EAU90477.1 - 0.23 11.8 2.3 0.44 10.8 0.2 2.4 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 DUF3347 PF11827.8 EAU90477.1 - 1.4 9.1 5.0 16 5.6 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) PIF1 PF05970.14 EAU90478.2 - 8.7e-57 192.9 0.5 8.6e-45 153.5 0.3 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAU90478.2 - 6.4e-23 81.5 0.0 1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU90478.2 - 1.7e-09 38.2 0.0 3.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EAU90478.2 - 3.8e-06 25.1 1.1 3e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 EAU90478.2 - 0.00013 21.8 0.3 1.4 8.6 0.0 3.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EAU90478.2 - 0.0003 20.6 0.0 0.0008 19.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 EAU90478.2 - 0.00035 20.1 0.1 0.0019 17.7 0.1 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EAU90478.2 - 0.0034 17.6 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU90478.2 - 0.0038 17.0 0.1 0.68 9.7 0.0 2.7 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAU90478.2 - 0.0077 16.2 0.2 0.09 12.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU90478.2 - 0.018 15.4 0.1 0.044 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EAU90478.2 - 0.021 14.3 0.0 0.091 12.2 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein SH3_13 PF18335.1 EAU90478.2 - 0.025 14.4 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA PF00004.29 EAU90478.2 - 0.031 14.7 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EAU90478.2 - 0.036 14.5 0.0 0.15 12.5 0.0 2.0 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EAU90478.2 - 0.038 13.9 0.3 0.89 9.5 0.1 2.5 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 EAU90478.2 - 0.046 12.8 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EAU90478.2 - 0.051 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EAU90478.2 - 0.054 13.4 0.2 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EAU90478.2 - 0.11 11.7 0.1 0.28 10.4 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Carb_kinase PF01256.17 EAU90481.2 - 1.1e-48 165.9 0.0 3.5e-37 128.2 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate kinase PGM_PMM_I PF02878.16 EAU90482.2 - 1.5e-37 128.3 0.1 2.4e-37 127.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EAU90482.2 - 7.3e-26 90.6 0.0 1.5e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EAU90482.2 - 7e-13 49.1 0.0 1.7e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EAU90482.2 - 0.00011 22.2 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2460 PF09343.10 EAU90482.2 - 0.0043 16.6 0.0 0.0067 15.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 2217 (DUF2460) DUF676 PF05057.14 EAU90483.2 - 1.1e-35 123.1 0.0 1.7e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EAU90483.2 - 0.00045 20.1 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAU90483.2 - 0.02 15.5 1.2 0.029 15.0 0.7 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 EAU90483.2 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase SIR2 PF02146.17 EAU90484.2 - 2.3e-29 102.6 0.0 3.9e-29 101.8 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Cript PF10235.9 EAU90487.1 - 5e-28 97.5 7.3 5e-28 97.5 7.3 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT Rhodanese_C PF12368.8 EAU90487.1 - 0.18 12.2 9.3 0.34 11.3 4.6 2.2 2 0 0 2 2 2 0 Rhodanase C-terminal DUF2039 PF10217.9 EAU90487.1 - 0.27 11.6 15.5 0.1 12.9 9.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_2 PF13240.6 EAU90487.1 - 2.3 8.0 19.2 9 6.2 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain PolC_DP2 PF03833.13 EAU90487.1 - 4.5 5.0 6.0 4.1 5.1 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf_UBZ PF18439.1 EAU90487.1 - 7.5 6.2 12.4 3.2 7.4 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger SNF2_N PF00176.23 EAU90488.2 - 4.1e-24 85.0 0.0 4.9e-16 58.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 EAU90488.2 - 2.4e-14 53.5 1.6 6.3e-14 52.1 0.0 2.5 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase IBR PF01485.21 EAU90488.2 - 0.022 15.0 16.7 0.41 10.9 2.4 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain MMS1_N PF10433.9 EAU90488.2 - 0.042 12.5 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term zf-AN1 PF01428.16 EAU90488.2 - 8.9 6.6 10.8 6 7.1 6.4 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C3HC4_2 PF13923.6 EAU90488.2 - 9.7 6.1 18.1 0.12 12.3 2.8 2.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PAP2 PF01569.21 EAU90489.2 - 2.1e-25 89.1 0.3 2.1e-25 89.1 0.3 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EAU90489.2 - 0.13 11.9 5.6 5.1 6.7 0.2 3.3 2 1 1 3 3 3 0 PAP2 superfamily CTD_bind PF04818.13 EAU90490.2 - 2.9e-05 24.8 0.0 7.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PET117 PF15786.5 EAU90491.1 - 3e-27 94.7 2.4 3.6e-27 94.4 2.4 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Auts2 PF15336.6 EAU90491.1 - 0.12 12.5 0.3 0.13 12.4 0.3 1.0 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein ubiquitin PF00240.23 EAU90492.1 - 3.4e-34 116.4 0.5 3.4e-34 116.4 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EAU90492.1 - 1e-26 92.8 2.0 1e-26 92.8 2.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EAU90492.1 - 3.3e-16 58.9 0.6 7.9e-16 57.7 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAU90492.1 - 2.9e-05 24.4 0.5 0.00014 22.2 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAU90492.1 - 0.00033 20.7 0.6 0.00074 19.6 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAU90492.1 - 0.0063 17.0 0.7 0.0089 16.6 0.7 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAU90492.1 - 0.0073 16.6 0.9 0.012 15.9 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAU90492.1 - 0.0074 16.2 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EAU90492.1 - 0.02 14.9 1.1 5.9 7.0 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 EAU90492.1 - 0.038 14.2 0.6 0.062 13.5 0.6 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF971 PF06155.12 EAU90492.1 - 0.15 12.7 0.2 0.32 11.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF971) Rep_fac_C PF08542.11 EAU90493.1 - 1.4e-21 76.7 0.1 5.8e-21 74.7 0.1 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 EAU90493.1 - 5.4e-18 65.7 0.0 9.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EAU90493.1 - 3.4e-15 56.2 0.0 3e-12 46.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.13 EAU90493.1 - 2.4e-07 30.7 0.1 6e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 EAU90493.1 - 2.9e-07 30.4 0.0 2.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EAU90493.1 - 3.9e-07 30.2 0.0 1.8e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 EAU90493.1 - 4.3e-06 26.8 0.0 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU90493.1 - 1.9e-05 24.6 0.1 3.8e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EAU90493.1 - 2.5e-05 23.6 0.0 3.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_assoc_2 PF16193.5 EAU90493.1 - 3.5e-05 24.1 0.1 0.00012 22.4 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_24 PF13479.6 EAU90493.1 - 4.5e-05 23.3 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU90493.1 - 6.4e-05 23.4 0.0 0.00013 22.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EAU90493.1 - 7.7e-05 23.1 1.4 0.016 15.6 0.4 3.0 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 EAU90493.1 - 0.00016 21.5 0.6 0.00071 19.4 0.7 1.9 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU90493.1 - 0.00025 21.3 0.7 0.56 10.5 0.1 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 EAU90493.1 - 0.00027 20.7 0.0 0.0005 19.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 EAU90493.1 - 0.00036 20.6 0.0 0.02 14.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EAU90493.1 - 0.0007 19.6 0.1 0.0057 16.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAU90493.1 - 0.00086 19.2 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EAU90493.1 - 0.0025 17.4 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Methyltransf_31 PF13847.6 EAU90493.1 - 0.003 17.4 0.3 0.041 13.7 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain Viral_helicase1 PF01443.18 EAU90493.1 - 0.005 16.6 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 EAU90493.1 - 0.0081 15.6 0.1 0.25 10.7 0.0 2.2 1 1 1 2 2 2 1 Bacterial TniB protein T2SSE PF00437.20 EAU90493.1 - 0.009 15.1 0.1 0.13 11.3 0.0 2.1 1 1 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EAU90493.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MCM PF00493.23 EAU90493.1 - 0.019 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain SNF2_N PF00176.23 EAU90493.1 - 0.021 13.5 0.0 0.043 12.5 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain Mg_chelatase PF01078.21 EAU90493.1 - 0.045 13.1 0.0 0.38 10.1 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EAU90493.1 - 0.048 13.9 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EAU90493.1 - 0.055 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_6 PF13174.6 EAU90493.1 - 0.062 14.0 2.2 2.3 9.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat YfdX PF10938.8 EAU90493.1 - 0.079 12.9 0.1 0.91 9.5 0.0 2.4 2 1 0 2 2 2 0 YfdX protein AAA_25 PF13481.6 EAU90493.1 - 0.089 12.4 0.0 0.8 9.3 0.1 2.5 2 1 0 2 2 2 0 AAA domain PIF1 PF05970.14 EAU90493.1 - 0.093 11.9 0.2 1.5 7.9 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase AAA_18 PF13238.6 EAU90493.1 - 0.15 12.6 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 EAU90494.2 - 4.6e-05 22.6 0.0 8.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU90494.2 - 0.017 15.3 1.6 0.031 14.4 1.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Paralemmin PF03285.15 EAU90494.2 - 0.043 13.4 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Paralemmin DUF1937 PF09152.10 EAU90494.2 - 0.18 12.7 0.0 0.47 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1937) Cation_efflux PF01545.21 EAU90495.1 - 9.5e-48 162.6 12.6 1.2e-47 162.2 12.6 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 EAU90495.1 - 0.0033 16.6 1.0 0.0033 16.6 1.0 2.2 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component ABA_GPCR PF12430.8 EAU90495.1 - 1.3 8.8 4.2 3.3 7.4 0.2 2.3 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Deltameth_res PF16020.5 EAU90495.1 - 2.1 8.3 5.1 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Deltamethrin resistance Zw10 PF06248.13 EAU90496.1 - 1.2e-21 76.9 2.7 5.9e-16 58.1 1.8 2.4 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EAU90496.1 - 8e-12 45.3 0.0 2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Occludin_ELL PF07303.13 EAU90496.1 - 0.0057 17.4 2.7 4.6 8.0 0.3 3.8 2 1 2 4 4 4 2 Occludin homology domain DraK_HK_N PF18092.1 EAU90496.1 - 0.078 13.4 0.3 0.32 11.5 0.1 2.2 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain DUF1664 PF07889.12 EAU90496.1 - 0.081 13.0 3.3 0.19 11.8 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) SesA PF17107.5 EAU90496.1 - 1.1 9.5 8.3 3.4 7.9 0.1 4.2 3 2 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases WD40 PF00400.32 EAU90498.1 - 9.6e-09 35.8 4.5 0.37 11.7 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat hGDE_N PF14699.6 EAU90499.1 - 0.16 12.1 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme DnaJ PF00226.31 EAU90500.2 - 7.4e-26 90.1 0.4 1.1e-25 89.5 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 EAU90500.2 - 3.6e-24 85.1 0.0 8.1e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Filament PF00038.21 EAU90500.2 - 0.15 11.6 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein F-box-like PF12937.7 EAU90501.1 - 5.2e-06 26.3 0.2 1.1e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like MIT PF04212.18 EAU90501.1 - 2.4e-05 24.3 3.2 2.4e-05 24.3 3.2 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain F-box PF00646.33 EAU90501.1 - 3.1e-05 23.7 0.2 6.3e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.6 EAU90501.1 - 0.012 15.3 0.5 1.7 8.4 0.0 2.5 1 1 1 2 2 2 0 TPR repeat TPR_2 PF07719.17 EAU90501.1 - 0.04 14.0 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box_4 PF15966.5 EAU90501.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 F-box TPR_14 PF13428.6 EAU90501.1 - 0.52 11.3 4.8 0.2 12.6 1.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat MBOAT PF03062.19 EAU90502.2 - 1.9e-35 122.8 12.9 1.9e-35 122.8 12.9 2.5 3 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EAU90502.2 - 0.00069 19.8 4.4 0.0015 18.8 2.5 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Fumarate_red_D PF02313.17 EAU90502.2 - 0.79 9.8 6.9 0.088 12.9 1.5 2.2 2 0 0 2 2 2 0 Fumarate reductase subunit D Clr2_transil PF16761.5 EAU90503.2 - 8e-26 90.7 0.0 1.6e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EAU90503.2 - 5.9e-10 40.1 2.3 5e-08 33.8 0.4 3.6 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 KAR9 PF08580.10 EAU90504.2 - 1.5e-34 119.7 0.2 1.5e-34 119.7 0.2 4.5 1 1 1 3 3 3 1 Yeast cortical protein KAR9 WDCP PF15390.6 EAU90504.2 - 0.0056 15.1 2.6 0.0097 14.3 2.6 1.3 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family PAP2 PF01569.21 EAU90504.2 - 0.058 13.2 0.0 0.058 13.2 0.0 2.1 2 0 0 2 2 2 0 PAP2 superfamily DUF5315 PF17242.2 EAU90504.2 - 0.07 13.0 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) TPR_19 PF14559.6 EAU90505.2 - 1.6e-10 41.3 4.1 4.1e-07 30.4 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU90505.2 - 9.2e-10 39.0 0.5 5.7e-07 30.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90505.2 - 6.1e-08 32.8 7.8 0.026 15.3 0.0 4.6 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU90505.2 - 3.1e-07 30.0 0.3 0.01 15.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90505.2 - 8.6e-06 25.6 0.4 0.0052 16.9 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU90505.2 - 2.2e-05 24.1 0.1 0.12 12.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAU90505.2 - 9.8e-05 22.1 3.6 0.0039 17.0 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU90505.2 - 0.00017 21.8 1.1 0.011 16.0 0.3 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90505.2 - 0.00092 18.9 0.0 0.37 10.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EAU90505.2 - 0.0014 18.1 0.7 0.012 15.1 0.2 2.1 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_20 PF14561.6 EAU90505.2 - 0.0076 16.6 3.5 1.2 9.5 0.3 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU90505.2 - 0.016 15.4 0.1 0.24 11.6 0.0 2.2 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EAU90505.2 - 0.019 15.3 0.2 1.2 9.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAU90505.2 - 0.019 15.1 0.5 21 5.4 0.0 3.5 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EAU90505.2 - 0.034 14.8 2.6 55 4.8 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU90505.2 - 0.043 13.5 0.3 0.77 9.5 0.0 2.7 2 1 1 3 3 3 0 TPR repeat TPR_21 PF09976.9 EAU90505.2 - 0.049 13.3 4.5 0.82 9.4 2.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain DUF410 PF04190.13 EAU90505.2 - 0.068 13.0 0.3 0.29 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF410) TPR_6 PF13174.6 EAU90505.2 - 0.11 13.2 0.1 4.5 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.7 EAU90506.1 - 0.00024 21.3 2.2 0.00034 20.8 2.2 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF1664 PF07889.12 EAU90506.1 - 0.002 18.2 1.0 0.033 14.2 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 EAU90506.1 - 0.0038 17.4 2.9 0.0068 16.6 2.9 1.4 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding KxDL PF10241.9 EAU90506.1 - 0.0073 16.6 1.1 0.68 10.3 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein GAS PF13851.6 EAU90506.1 - 0.0085 15.5 1.0 0.01 15.2 1.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding LMBR1 PF04791.16 EAU90506.1 - 0.0087 15.0 0.2 0.012 14.5 0.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein TMPIT PF07851.13 EAU90506.1 - 0.01 15.1 0.9 0.01 15.1 0.9 1.5 2 0 0 2 2 2 0 TMPIT-like protein EzrA PF06160.12 EAU90506.1 - 0.028 12.6 0.4 0.036 12.2 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 EAU90506.1 - 0.042 14.0 0.9 0.098 12.8 0.9 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MIF4G_like_2 PF09090.11 EAU90506.1 - 0.052 13.0 0.3 0.064 12.7 0.3 1.1 1 0 0 1 1 1 0 MIF4G like Mer2 PF09074.10 EAU90506.1 - 0.053 13.3 0.5 0.077 12.8 0.5 1.2 1 0 0 1 1 1 0 Mer2 MPS2 PF17060.5 EAU90506.1 - 0.079 12.2 0.9 0.15 11.3 0.8 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 Cortex-I_coil PF09304.10 EAU90506.1 - 0.092 13.0 1.9 0.12 12.6 0.3 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil Prefoldin_2 PF01920.20 EAU90506.1 - 0.098 12.6 2.3 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Med30 PF11315.8 EAU90506.1 - 0.099 12.8 0.3 0.5 10.6 0.3 1.9 1 1 0 1 1 1 0 Mediator complex subunit 30 Rop-like PF05082.13 EAU90506.1 - 0.12 12.3 2.9 0.84 9.5 0.2 2.4 1 1 1 2 2 2 0 Rop-like Mce4_CUP1 PF11887.8 EAU90506.1 - 0.19 11.2 0.1 0.63 9.5 0.0 1.7 1 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Seryl_tRNA_N PF02403.22 EAU90506.1 - 0.2 11.9 1.4 0.47 10.7 1.4 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Vps5 PF09325.10 EAU90507.2 - 5.9e-57 192.9 15.8 3.8e-55 187.0 15.8 2.2 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EAU90507.2 - 7.3e-25 87.2 0.1 1.2e-23 83.2 0.0 2.3 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EAU90507.2 - 0.00023 20.7 1.0 0.00038 20.0 1.0 1.2 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR_3 PF16746.5 EAU90507.2 - 0.013 15.3 7.0 0.02 14.6 7.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family Arfaptin PF06456.13 EAU90507.2 - 0.16 11.5 4.7 8.3 5.9 4.7 2.2 1 1 0 1 1 1 0 Arfaptin-like domain DUF3450 PF11932.8 EAU90507.2 - 0.5 9.6 9.0 3.1 7.0 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DWNN PF08783.11 EAU90508.1 - 2.7e-25 88.4 0.1 6.8e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EAU90508.1 - 8e-11 41.6 6.5 1.6e-10 40.6 6.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EAU90508.1 - 2e-06 27.6 1.6 3.9e-06 26.7 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 EAU90508.1 - 6e-06 26.3 0.0 6e-05 23.2 0.0 2.5 1 1 1 2 2 2 1 U-box domain zf-CCHC_3 PF13917.6 EAU90508.1 - 0.0014 18.5 0.3 0.0037 17.2 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle Efg1 PF10153.9 EAU90508.1 - 0.0063 16.9 0.4 0.017 15.4 0.4 1.7 1 0 0 1 1 1 1 rRNA-processing protein Efg1 zf-C3HC4_3 PF13920.6 EAU90508.1 - 0.0094 15.8 6.6 0.0094 15.8 6.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU90508.1 - 0.022 14.6 9.7 0.022 14.6 9.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 EAU90508.1 - 0.036 13.8 0.5 0.036 13.8 0.5 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-RING_UBOX PF13445.6 EAU90508.1 - 0.15 12.1 6.3 0.32 11.1 6.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Nucleoporin_FG2 PF15967.5 EAU90508.1 - 0.92 8.0 11.1 0.29 9.6 4.1 2.2 2 0 0 2 2 2 0 Nucleoporin FG repeated region zf-RING_5 PF14634.6 EAU90508.1 - 1.4 8.9 13.1 0.16 11.9 7.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAU90508.1 - 1.5 9.0 8.8 3.7 7.8 8.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EAU90508.1 - 3.1 7.8 9.5 7.1 6.6 9.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU90508.1 - 5.2 7.5 15.0 0.12 12.7 8.5 1.7 2 0 0 2 2 1 0 Ring finger domain ERG4_ERG24 PF01222.17 EAU90509.2 - 1.8e-125 419.1 28.2 2.1e-125 418.9 28.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EAU90509.2 - 2.6e-06 27.1 3.1 5.1e-06 26.2 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EAU90509.2 - 0.00012 22.5 0.3 0.00012 22.5 0.3 2.9 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FAT PF02259.23 EAU90510.2 - 1.6e-114 382.8 3.5 1.6e-114 382.8 3.5 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EAU90510.2 - 1.9e-70 237.5 0.3 1.3e-69 234.8 0.1 2.5 3 0 0 3 3 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EAU90510.2 - 1.3e-57 194.2 5.0 1.5e-54 184.3 0.5 5.4 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EAU90510.2 - 3.7e-40 136.3 0.0 3.7e-40 136.3 0.0 3.7 4 0 0 4 4 4 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EAU90510.2 - 8.7e-19 67.7 17.3 0.01 16.2 0.0 11.0 11 1 1 12 12 11 5 HEAT repeats FATC PF02260.20 EAU90510.2 - 1.5e-16 59.9 0.5 4e-16 58.5 0.5 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EAU90510.2 - 7.3e-14 50.7 13.6 0.12 12.7 0.1 10.6 11 0 0 11 11 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EAU90510.2 - 1.8e-09 38.1 0.0 4.3 8.0 0.0 7.8 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EAU90510.2 - 6.3e-07 29.8 22.7 0.0026 18.2 1.3 10.4 11 1 1 12 12 11 2 HEAT-like repeat TPR_19 PF14559.6 EAU90510.2 - 5.2e-06 26.9 0.0 0.019 15.4 0.0 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Cnd1 PF12717.7 EAU90510.2 - 1.6e-05 25.0 1.3 1.5 8.9 0.0 5.0 3 3 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EAU90510.2 - 5.1e-05 23.0 2.4 0.4 10.2 0.0 5.5 6 0 0 6 6 6 1 CLASP N terminal TPR_7 PF13176.6 EAU90510.2 - 0.00024 20.9 1.3 0.16 12.1 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU90510.2 - 0.00088 19.2 1.8 9.5 6.6 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU90510.2 - 0.048 13.9 4.8 7.1 7.0 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90510.2 - 0.087 13.7 1.4 5.3 8.1 0.0 4.9 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EAU90510.2 - 0.096 12.8 2.8 4.9 7.4 0.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RTP1_C1 PF10363.9 EAU90510.2 - 0.2 11.9 0.6 18 5.6 0.1 4.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Actin PF00022.19 EAU90511.2 - 1.6e-28 99.4 0.0 1.2e-12 47.2 0.0 3.1 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 EAU90511.2 - 1.4e-13 50.8 0.0 1.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 EAU90511.2 - 0.0039 16.1 0.1 0.078 11.8 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Etmic-2 PF06670.11 EAU90511.2 - 0.064 12.2 0.9 0.091 11.7 0.1 1.6 1 1 1 2 2 2 0 Microneme protein Etmic-2 FOXP-CC PF16159.5 EAU90513.2 - 0.0063 17.1 0.2 0.015 15.9 0.2 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-C2H2 PF00096.26 EAU90513.2 - 0.019 15.4 0.5 0.081 13.4 0.5 2.2 1 0 0 1 1 1 0 Zinc finger, C2H2 type RCC1 PF00415.18 EAU90514.2 - 5.1e-16 59.0 4.7 0.0055 17.3 0.0 6.4 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAU90514.2 - 6e-15 54.6 24.3 5.6e-07 29.2 0.3 6.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EAU90514.2 - 6.3e-06 26.0 0.8 1.7e-05 24.6 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EAU90514.2 - 0.051 13.5 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 F-box DUF1921 PF09081.10 EAU90514.2 - 0.41 10.9 3.9 1.7 8.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) F-box PF00646.33 EAU90514.2 - 7.7 6.5 7.6 0.53 10.2 1.9 2.1 2 1 0 2 2 2 0 F-box domain Peptidase_M28 PF04389.17 EAU90516.1 - 2.5e-27 95.8 0.0 3.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAU90516.1 - 1.4e-09 37.9 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EAU90516.1 - 0.012 14.7 0.0 0.28 10.2 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase FGGY_N PF00370.21 EAU90517.1 - 3.1e-25 89.2 0.0 5.7e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EAU90517.1 - 6.2e-25 88.1 0.0 2.6e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain DUF2417 PF10329.9 EAU90519.1 - 0.091 12.2 0.4 1.7 8.0 0.0 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) TMEM208_SND2 PF05620.11 EAU90519.1 - 0.18 11.5 0.2 0.56 10.0 0.0 1.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 NUDIX PF00293.28 EAU90520.2 - 1.9e-06 27.9 0.0 4.3e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EAU90520.2 - 0.0004 20.4 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) Aa_trans PF01490.18 EAU90521.2 - 1.4e-86 290.8 19.1 1.6e-86 290.6 19.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EAU90521.2 - 7.8e-05 21.9 14.9 7.8e-05 21.9 14.9 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family ATP-synt_8 PF00895.20 EAU90521.2 - 0.4 11.2 5.5 5 7.7 0.9 3.2 2 1 1 3 3 3 0 ATP synthase protein 8 SUZ PF12752.7 EAU90522.2 - 4.1e-14 53.1 5.0 4.1e-14 53.1 5.0 6.2 5 3 0 5 5 5 1 SUZ domain R3H PF01424.22 EAU90522.2 - 0.0025 17.8 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain RNA_pol_Rpb4 PF03874.16 EAU90524.1 - 1.4e-18 67.4 0.4 2e-18 66.9 0.4 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Pneumovirus_M2 PF06436.11 EAU90524.1 - 0.085 12.3 0.1 0.19 11.2 0.1 1.6 1 1 1 2 2 2 0 Pneumovirus matrix protein 2 (M2) PseudoU_synth_1 PF01416.20 EAU90525.1 - 1.2e-12 48.2 0.0 8e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Presenilin PF01080.17 EAU90525.1 - 2.1 7.1 5.6 2.8 6.6 5.6 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 EAU90526.1 - 9.6e-34 117.5 78.2 1.2e-31 110.6 78.2 2.9 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 OTT_1508_deam PF14441.6 EAU90528.2 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase SF3b1 PF08920.10 EAU90529.1 - 3.4e-23 82.4 2.7 3.4e-23 82.4 2.7 2.3 2 0 0 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EAU90529.1 - 2e-11 44.1 11.8 0.65 10.4 0.0 8.0 4 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 EAU90529.1 - 2e-11 44.1 10.1 0.00052 20.5 0.0 8.1 9 1 1 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EAU90529.1 - 1.2e-07 32.2 1.4 0.23 12.1 0.0 5.4 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EAU90529.1 - 1.8e-07 30.8 13.4 0.018 15.3 0.2 9.5 13 0 0 13 13 10 1 HEAT repeat Adaptin_N PF01602.20 EAU90529.1 - 2.5e-07 29.6 3.2 0.011 14.4 0.1 3.4 2 1 0 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 EAU90529.1 - 1.1e-05 25.6 8.7 0.65 10.0 0.0 6.6 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 NUC173 PF08161.12 EAU90529.1 - 1.8e-05 24.5 0.9 1.2 8.8 0.0 5.2 4 1 1 5 5 5 2 NUC173 domain UME PF08064.13 EAU90529.1 - 0.00011 22.1 0.4 0.31 11.0 0.0 5.0 5 2 2 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 EAU90529.1 - 0.0002 21.0 0.9 1.2 8.6 0.0 3.9 3 1 0 3 3 3 2 CLASP N terminal DUF3385 PF11865.8 EAU90529.1 - 0.0059 16.5 2.3 1.6 8.6 0.1 4.8 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) DUF3110 PF11360.8 EAU90529.1 - 0.025 14.8 0.1 0.1 12.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dopey_N PF04118.14 EAU90529.1 - 0.041 13.0 2.1 2.1 7.4 0.0 3.6 4 0 0 4 4 4 0 Dopey, N-terminal DUF3730 PF12530.8 EAU90529.1 - 0.059 12.9 0.1 0.46 10.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) Adaptin_N PF01602.20 EAU90530.1 - 1.1e-143 479.6 9.2 1.3e-143 479.4 9.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EAU90530.1 - 1.9e-22 79.7 0.1 1.9e-22 79.7 0.1 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 EAU90530.1 - 2.2e-10 40.8 7.3 1.6e-06 28.2 0.3 4.1 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAU90530.1 - 7e-05 23.1 1.3 1.4 9.3 0.0 4.5 4 1 1 5 5 5 2 HEAT repeats RICTOR_M PF14666.6 EAU90530.1 - 0.0027 17.4 0.3 0.16 11.8 0.0 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain Peptidase_M73 PF12389.8 EAU90530.1 - 0.015 15.1 0.3 0.026 14.3 0.3 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase MMS19_N PF14500.6 EAU90530.1 - 0.029 14.0 0.4 5.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 EAU90530.1 - 0.055 13.8 4.8 1.1e+02 3.5 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat TIP120 PF08623.10 EAU90530.1 - 0.88 9.3 3.4 3 7.6 0.4 3.0 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Peptidase_S10 PF00450.22 EAU90532.2 - 4.9e-48 164.6 0.0 1.9e-47 162.6 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase GCFC PF07842.12 EAU90533.2 - 1.2e-78 264.5 10.9 2.2e-78 263.7 10.9 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 EAU90533.2 - 2.8e-18 66.2 15.9 2.8e-18 66.2 15.9 3.3 3 0 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 EAU90533.2 - 3.7e-13 49.1 1.5 3.7e-13 49.1 1.5 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EAU90533.2 - 1.8e-06 27.9 5.1 2.5e-06 27.5 1.5 3.1 2 0 0 2 2 2 1 G-patch domain OmpH PF03938.14 EAU90533.2 - 0.22 11.9 14.5 1.3 9.4 0.7 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 EAU90533.2 - 1.2 8.3 4.4 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 TMPIT-like protein WD40 PF00400.32 EAU90534.2 - 9.4e-08 32.6 0.0 0.078 13.9 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU90534.2 - 0.0084 16.4 0.0 2 8.8 0.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PH_12 PF16457.5 EAU90535.2 - 3.2e-34 118.4 0.0 5.9e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 EAU90535.2 - 2.3e-30 106.0 0.0 3.6e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 EAU90535.2 - 2.6e-29 102.1 0.0 5.6e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) FERM_N PF09379.10 EAU90535.2 - 0.014 15.4 0.0 0.074 13.0 0.0 2.2 2 0 0 2 2 2 0 FERM N-terminal domain MTHFR PF02219.17 EAU90536.2 - 1.9e-108 362.1 0.0 2.6e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Radical_SAM PF04055.21 EAU90536.2 - 0.088 13.2 0.0 15 5.9 0.0 2.5 3 0 0 3 3 3 0 Radical SAM superfamily DUF202 PF02656.15 EAU90537.1 - 2e-05 24.9 0.5 0.00032 21.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CopD PF05425.13 EAU90537.1 - 0.047 14.1 0.2 0.047 14.1 0.2 2.1 1 1 0 2 2 2 0 Copper resistance protein D MttA_Hcf106 PF02416.16 EAU90537.1 - 0.12 11.8 1.0 4.2 6.8 0.2 2.6 3 0 0 3 3 3 0 mttA/Hcf106 family DUF2157 PF09925.9 EAU90537.1 - 2.3 8.0 7.5 31 4.3 7.5 2.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Pkinase PF00069.25 EAU90539.1 - 5.6e-70 235.7 0.0 8.9e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU90539.1 - 1.8e-37 129.1 0.0 3.6e-37 128.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAU90539.1 - 0.0002 20.4 0.0 0.0002 20.4 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EAU90539.1 - 0.00079 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAU90539.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynein_light PF01221.18 EAU90540.2 - 9.7e-40 134.8 0.8 1.1e-39 134.6 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 He_PIG PF05345.12 EAU90541.1 - 1.8e-11 44.0 13.8 2.2e-07 31.0 4.6 4.9 4 0 0 4 4 4 3 Putative Ig domain HEAT_EZ PF13513.6 EAU90542.2 - 7.4e-18 64.7 17.4 0.0045 17.5 0.0 11.1 10 2 2 12 12 12 3 HEAT-like repeat HEAT PF02985.22 EAU90542.2 - 9e-18 62.8 16.4 0.00037 20.5 0.0 9.8 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 EAU90542.2 - 8.3e-13 48.5 6.0 0.096 13.1 0.0 7.4 5 2 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 EAU90542.2 - 2.6e-10 40.6 0.2 0.0012 18.9 0.0 4.5 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EAU90542.2 - 9.9e-09 35.0 0.8 8.5e-08 32.0 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EAU90542.2 - 1.1e-06 27.5 0.2 0.041 12.4 0.0 3.7 3 1 0 3 3 3 2 Adaptin N terminal region IFRD PF05004.13 EAU90542.2 - 6.8e-06 25.4 2.9 0.042 13.0 0.0 4.2 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 EAU90542.2 - 1e-05 25.4 0.0 0.45 10.2 0.0 4.5 3 1 0 3 3 3 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 EAU90542.2 - 1.3e-05 25.2 3.0 14 5.6 0.0 6.5 5 2 1 6 6 6 0 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EAU90542.2 - 0.00017 21.2 1.6 11 5.6 0.0 4.8 4 1 1 5 5 5 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 EAU90542.2 - 0.0012 19.4 0.1 1.9 9.1 0.0 5.1 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region Xpo1 PF08389.12 EAU90542.2 - 0.0036 17.4 0.1 5.6 7.0 0.0 4.2 3 1 1 4 4 4 1 Exportin 1-like protein Importin_rep_6 PF18829.1 EAU90542.2 - 0.0038 17.3 0.1 1.1 9.4 0.0 3.5 2 0 0 2 2 2 1 Importin repeat 6 GRIP PF01465.20 EAU90542.2 - 0.011 15.7 0.1 8.7 6.4 0.0 4.0 4 0 0 4 4 4 0 GRIP domain DHO_dh PF01180.21 EAU90543.1 - 4e-98 328.3 0.0 5e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 EAU90543.1 - 0.0052 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 EAU90543.1 - 0.067 12.2 0.1 0.2 10.7 0.1 1.9 1 1 0 1 1 1 0 FMN-dependent dehydrogenase BTB PF00651.31 EAU90544.2 - 0.0002 21.6 0.0 0.00061 20.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Salp15 PF12115.8 EAU90545.1 - 0.59 10.6 3.7 5.5 7.5 0.4 2.3 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation CAP_N PF01213.19 EAU90545.1 - 7.6 5.9 20.5 1.8 8.0 5.3 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sugar_tr PF00083.24 EAU90547.2 - 1.6e-94 317.3 11.9 7.4e-94 315.1 10.6 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EAU90547.2 - 2.2e-29 102.5 23.1 2.8e-29 102.2 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2105 PF09878.9 EAU90547.2 - 3.2 7.4 9.1 0.28 10.9 1.9 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2105) AIP3 PF03915.13 EAU90549.2 - 4.7e-148 493.6 10.2 7.6e-148 492.9 10.2 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 ISG65-75 PF11727.8 EAU90549.2 - 0.041 13.1 0.9 0.13 11.5 0.6 2.0 1 1 0 1 1 1 0 Invariant surface glycoprotein DUF2399 PF09664.10 EAU90549.2 - 0.068 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Syntaxin-6_N PF09177.11 EAU90549.2 - 0.073 13.6 12.0 2.7 8.6 0.0 4.2 4 1 0 4 4 4 0 Syntaxin 6, N-terminal Terpene_synth_C PF03936.16 EAU90549.2 - 0.084 12.2 2.3 0.14 11.5 1.2 1.8 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Sec20 PF03908.13 EAU90549.2 - 0.32 10.9 2.1 3.8 7.5 0.5 3.2 2 0 0 2 2 2 0 Sec20 Sec34 PF04136.15 EAU90549.2 - 0.34 10.8 6.1 5.2 6.9 0.5 3.1 3 0 0 3 3 3 0 Sec34-like family Lectin_N PF03954.14 EAU90549.2 - 0.6 9.9 6.4 0.16 11.7 0.6 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain COG5 PF10392.9 EAU90549.2 - 0.6 10.3 4.3 26 5.0 0.1 3.3 2 1 0 2 2 2 0 Golgi transport complex subunit 5 E2F_CC-MB PF16421.5 EAU90549.2 - 1.5 9.2 0.0 1.5 9.2 0.0 3.6 4 0 0 4 4 4 0 E2F transcription factor CC-MB domain Prominin PF05478.11 EAU90549.2 - 2.8 5.8 6.0 4.6 5.1 3.8 2.2 2 0 0 2 2 2 0 Prominin LPP PF04728.13 EAU90549.2 - 6.5 7.2 7.0 33 5.0 0.8 3.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper HIP1_clath_bdg PF16515.5 EAU90549.2 - 6.9 7.4 21.5 0.21 12.2 1.9 4.5 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EAU90549.2 - 7.5 6.6 9.6 79 3.3 5.6 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Metallophos PF00149.28 EAU90550.2 - 3.4e-16 60.4 0.2 1.5e-15 58.3 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L23 PF00276.20 EAU90551.1 - 6.3e-10 39.3 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Mac PF12464.8 EAU90551.1 - 0.66 10.3 2.2 60 4.0 0.1 3.4 3 1 0 3 3 3 0 Maltose acetyltransferase LRR_8 PF13855.6 EAU90552.1 - 3.1e-07 30.0 3.9 2.9e-06 26.9 1.2 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EAU90552.1 - 3.4e-07 30.5 5.4 0.00064 20.1 1.6 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) zf-C2H2 PF00096.26 EAU90553.1 - 1.5e-24 85.0 45.3 2.5e-06 27.6 1.7 8.7 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU90553.1 - 4.9e-22 77.3 41.6 2.3e-06 27.8 0.8 7.7 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU90553.1 - 4.5e-17 61.3 40.8 0.0005 20.7 1.4 8.5 9 0 0 9 9 8 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EAU90553.1 - 1.6e-06 28.3 18.1 0.0063 16.8 3.5 5.1 2 1 3 5 5 5 3 C2H2-type zinc ribbon FOXP-CC PF16159.5 EAU90553.1 - 5.9e-06 26.8 36.2 0.0062 17.1 0.4 7.6 5 2 3 8 8 7 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EAU90553.1 - 6.3e-06 26.3 10.8 0.0038 17.5 0.5 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EAU90553.1 - 0.00015 21.4 1.7 0.00015 21.4 1.7 5.6 6 0 0 6 6 6 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EAU90553.1 - 0.00073 19.5 30.4 0.26 11.3 1.9 7.2 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EAU90553.1 - 0.0021 17.9 4.8 6 6.9 0.0 4.9 4 0 0 4 4 4 1 zinc-finger of a C2HC-type zf_ZIC PF18366.1 EAU90553.1 - 0.0041 17.2 17.6 0.025 14.7 0.3 5.7 7 1 1 8 8 7 2 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 EAU90553.1 - 0.018 15.4 19.4 0.91 9.9 0.4 4.2 3 2 1 4 4 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 EAU90553.1 - 0.022 14.8 0.7 0.022 14.8 0.7 4.5 5 1 0 5 5 5 0 BED zinc finger PyrI_C PF02748.15 EAU90553.1 - 0.11 12.4 2.4 0.24 11.3 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_11 PF16622.5 EAU90553.1 - 0.14 12.0 21.6 2.1 8.2 0.6 5.8 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 EAU90553.1 - 1.2 9.1 8.1 58 3.6 0.1 4.7 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 EAU90553.1 - 1.2 9.7 14.6 1.3 9.6 0.7 3.9 3 1 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EAU90553.1 - 1.5 9.4 20.7 2.5 8.6 1.6 5.3 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 EAU90553.1 - 2.8 7.6 11.0 1.1 8.9 0.5 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Zn_Tnp_IS1 PF03811.13 EAU90553.1 - 6.8 6.5 8.2 1 9.1 3.3 2.3 2 0 0 2 2 1 0 InsA N-terminal domain CTP_transf_like PF01467.26 EAU90554.2 - 6e-19 68.7 0.0 8.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_binding_3 PF01494.19 EAU90555.2 - 7.7e-32 110.9 0.0 1.5e-27 96.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 EAU90556.2 - 9e-39 133.7 0.0 1.4e-29 103.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EAU90556.2 - 1.1e-05 25.5 0.1 3e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU90556.2 - 1.7e-05 24.2 0.2 0.0023 17.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU90556.2 - 3.7e-05 23.0 0.0 7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAU90556.2 - 5.3e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EAU90556.2 - 0.00025 20.8 0.1 0.00041 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EAU90556.2 - 0.00068 20.1 0.0 0.0086 16.6 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU90556.2 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EAU90556.2 - 0.0012 18.1 0.2 0.002 17.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAU90556.2 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EAU90556.2 - 0.089 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EAU90556.2 - 0.097 11.7 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EAU90557.2 - 3.5e-48 164.6 0.0 4.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Tma16 PF11176.8 EAU90558.2 - 3.9e-45 153.3 2.7 4.7e-45 153.0 2.7 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Death PF00531.22 EAU90558.2 - 0.072 13.3 0.1 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Death domain MOZART1 PF12554.8 EAU90559.1 - 3.8e-24 84.2 0.5 4.6e-24 83.9 0.5 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Zds_C PF08632.10 EAU90560.2 - 2e-28 97.9 1.0 3.6e-28 97.1 1.0 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pinin_SDK_memA PF04696.13 EAU90560.2 - 0.34 11.0 20.3 1.4 9.0 15.9 2.9 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region P34-Arc PF04045.14 EAU90562.2 - 1.9e-109 365.0 0.0 2.2e-109 364.8 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Sec6 PF06046.13 EAU90564.2 - 1.1e-150 502.8 7.0 1.1e-150 502.8 7.0 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 GCP_N_terminal PF17681.1 EAU90564.2 - 0.011 15.3 2.6 3.6 7.1 0.2 3.0 3 0 0 3 3 3 0 Gamma tubulin complex component N-terminal HECT PF00632.25 EAU90564.2 - 0.035 13.6 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) YscO-like PF16789.5 EAU90564.2 - 0.11 12.5 0.1 0.11 12.5 0.1 3.9 5 0 0 5 5 5 0 YscO-like protein SKA2 PF16740.5 EAU90564.2 - 0.26 11.1 10.1 0.82 9.5 0.7 4.2 5 0 0 5 5 5 0 Spindle and kinetochore-associated protein 2 DUF1759 PF03564.15 EAU90564.2 - 0.57 10.1 5.8 3.4 7.6 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF1759) DUF1664 PF07889.12 EAU90564.2 - 1.4 9.0 7.1 0.74 9.9 0.7 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EAU90564.2 - 5.1 7.2 13.9 24 5.0 0.2 4.8 4 2 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Fes1 PF08609.10 EAU90564.2 - 5.8 7.9 7.2 1.9 9.4 0.2 3.6 4 1 0 4 4 4 0 Nucleotide exchange factor Fes1 FAD_binding_3 PF01494.19 EAU90565.2 - 5.7e-16 58.7 0.0 3.5e-07 29.8 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain SE PF08491.10 EAU90565.2 - 1.7e-05 24.0 0.0 2.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase DUF4407 PF14362.6 EAU90567.2 - 0.021 14.2 0.4 0.029 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EAU90567.2 - 0.021 14.8 0.9 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LXG PF04740.12 EAU90567.2 - 0.026 14.2 0.3 0.087 12.5 0.0 1.8 2 0 0 2 2 2 0 LXG domain of WXG superfamily ApoO PF09769.9 EAU90567.2 - 0.035 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein O APG17 PF04108.12 EAU90567.2 - 0.036 13.2 2.9 0.066 12.3 2.9 1.5 1 1 0 1 1 1 0 Autophagy protein Apg17 LidA_Long_CC PF18641.1 EAU90567.2 - 0.1 12.7 1.0 0.21 11.7 1.0 1.5 1 1 0 1 1 1 0 LidA long coiled-coil domain DUF1043 PF06295.12 EAU90567.2 - 0.13 12.3 0.9 0.6 10.1 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1043) COG2 PF06148.11 EAU90567.2 - 0.15 12.2 1.4 0.96 9.5 0.2 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.13 EAU90567.2 - 1.6 8.9 5.5 0.56 10.3 0.4 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PIF1 PF05970.14 EAU90568.2 - 1.4e-71 241.7 0.0 9.6e-70 235.6 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 EAU90568.2 - 5.3e-39 134.4 0.0 1.2e-38 133.2 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 EAU90568.2 - 6e-14 52.2 0.0 2.1e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU90568.2 - 1.3e-05 25.5 0.0 0.0002 21.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EAU90568.2 - 3.5e-05 23.7 0.2 0.031 14.0 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 EAU90568.2 - 4.3e-05 21.7 0.0 0.037 12.0 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_16 PF13191.6 EAU90568.2 - 0.00015 22.2 0.0 0.00042 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EAU90568.2 - 0.00015 21.1 0.0 0.00087 18.6 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 EAU90568.2 - 0.0038 17.2 0.0 0.021 14.8 0.0 2.2 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EAU90568.2 - 0.02 15.3 0.0 0.074 13.5 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Phage_GPA PF05840.13 EAU90568.2 - 0.025 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) AAA_33 PF13671.6 EAU90568.2 - 0.025 14.7 0.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EAU90568.2 - 0.031 13.2 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region CbiA PF01656.23 EAU90568.2 - 0.057 13.5 0.2 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 EAU90568.2 - 0.069 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAU90568.2 - 0.075 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 EAU90568.2 - 0.089 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_11 PF13086.6 EAU90568.2 - 0.092 12.5 0.1 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EAU90568.2 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 EAU90568.2 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EAU90568.2 - 0.12 12.3 0.0 0.45 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 EAU90568.2 - 0.16 11.6 0.0 0.48 10.1 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase CLP1_P PF16575.5 EAU90568.2 - 0.17 11.6 0.1 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 EAU90568.2 - 0.18 12.4 0.0 0.59 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAU90568.2 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF4131 PF13567.6 EAU90569.1 - 0.063 12.9 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ISP3_C PF18045.1 EAU90569.1 - 0.26 11.2 0.0 0.96 9.3 0.0 1.8 2 0 0 2 2 2 0 ISP3 C-terminal DUF4974 PF16344.5 EAU90576.2 - 0.13 12.2 0.0 18 5.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4974) ELYS PF13934.6 EAU90577.2 - 9.5e-40 136.9 0.0 1.4e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Mito_carr PF00153.27 EAU90579.1 - 2.2e-31 107.6 6.1 9.8e-18 63.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DHBP_synthase PF00926.19 EAU90580.1 - 2.1e-86 288.4 0.2 2.4e-86 288.2 0.2 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-RING_2 PF13639.6 EAU90581.2 - 1e-05 25.8 2.3 0.00023 21.4 0.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EAU90581.2 - 6.6e-05 22.6 4.3 0.0056 16.4 0.7 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-rbx1 PF12678.7 EAU90581.2 - 0.0013 19.0 1.7 0.0023 18.2 0.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain PQ-loop PF04193.14 EAU90581.2 - 0.006 16.3 0.4 0.016 15.0 0.4 1.7 1 0 0 1 1 1 1 PQ loop repeat zf-C3HC4_2 PF13923.6 EAU90581.2 - 0.036 13.9 5.2 0.094 12.6 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU90581.2 - 0.083 12.9 3.3 0.1 12.6 0.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 EAU90581.2 - 0.12 12.4 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EAU90581.2 - 0.14 12.0 3.1 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EAU90581.2 - 0.28 11.4 2.4 1.1 9.5 0.7 2.5 3 0 0 3 3 3 0 FANCL C-terminal domain Tyrosinase PF00264.20 EAU90582.2 - 9.8e-30 104.5 0.0 1.5e-28 100.6 0.0 2.1 1 1 1 2 2 2 1 Common central domain of tyrosinase Nnf1 PF03980.14 EAU90582.2 - 9.4e-12 45.3 2.7 2.4e-11 44.0 2.7 1.6 1 0 0 1 1 1 1 Nnf1 DUF3450 PF11932.8 EAU90582.2 - 0.005 16.2 3.4 0.0077 15.6 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) FPP PF05911.11 EAU90582.2 - 0.0084 14.4 2.6 0.01 14.1 2.6 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 EAU90582.2 - 0.0085 16.1 0.4 0.018 15.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CortBP2 PF09727.9 EAU90582.2 - 0.0087 16.0 2.6 0.013 15.4 2.6 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 ATP-synt_B PF00430.18 EAU90582.2 - 0.011 15.8 2.6 0.019 15.1 2.6 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CENP-F_leu_zip PF10473.9 EAU90582.2 - 0.029 14.4 5.7 0.056 13.5 5.7 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SPATA24 PF15175.6 EAU90582.2 - 0.038 13.9 3.1 0.061 13.2 3.1 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF3327 PF11806.8 EAU90582.2 - 0.04 14.6 0.1 0.075 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) ABC_tran_CTD PF16326.5 EAU90582.2 - 0.068 13.4 10.2 0.064 13.5 8.4 1.9 2 0 0 2 2 1 0 ABC transporter C-terminal domain ZapB PF06005.12 EAU90582.2 - 0.068 13.6 5.7 0.15 12.5 5.7 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Lzipper-MIP1 PF14389.6 EAU90582.2 - 0.07 13.4 4.1 0.16 12.3 4.1 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 PTH2 PF01981.16 EAU90582.2 - 0.086 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Spc7 PF08317.11 EAU90582.2 - 0.11 11.4 6.8 0.17 10.7 6.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1043 PF06295.12 EAU90582.2 - 0.15 12.1 3.6 29 4.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) EntA_Immun PF08951.10 EAU90582.2 - 0.22 11.9 0.2 0.22 11.9 0.2 2.0 2 0 0 2 2 2 0 Enterocin A Immunity DUF4407 PF14362.6 EAU90582.2 - 0.53 9.6 4.5 0.73 9.1 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SKA1 PF07160.12 EAU90582.2 - 1.5 8.6 7.5 0.82 9.5 4.5 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4404 PF14357.6 EAU90582.2 - 3.9 8.2 8.5 9.2 7.0 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) YabA PF06156.13 EAU90582.2 - 5 7.8 6.3 9.5 6.9 5.5 1.9 1 1 0 1 1 1 0 Initiation control protein YabA F-box_5 PF18511.1 EAU90583.2 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 F-box Leo1 PF04004.13 EAU90584.2 - 4.4e-52 176.3 0.3 9.9e-52 175.1 0.3 1.6 1 0 0 1 1 1 1 Leo1-like protein Atx10homo_assoc PF09759.9 EAU90585.2 - 8.4e-10 38.6 0.0 2.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain GBV-C_env PF12786.7 EAU90585.2 - 0.18 10.5 1.3 0.27 9.9 0.2 1.7 2 0 0 2 2 2 0 GB virus C genotype envelope DUF3106 PF11304.8 EAU90585.2 - 0.22 12.0 0.0 0.22 12.0 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) BRAP2 PF07576.12 EAU90587.2 - 9.3e-30 102.8 0.0 1.8e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EAU90587.2 - 2.4e-20 72.6 5.2 5.6e-20 71.4 5.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EAU90587.2 - 3.4e-08 33.7 9.2 3.4e-08 33.7 9.2 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU90587.2 - 2.7e-06 27.1 9.2 6.6e-06 25.9 9.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU90587.2 - 1.4e-05 24.9 7.5 3.4e-05 23.6 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EAU90587.2 - 1.5e-05 25.2 5.3 4.2e-05 23.8 5.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EAU90587.2 - 1.8e-05 24.3 4.7 5.4e-05 22.9 4.7 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EAU90587.2 - 2.7e-05 24.1 4.8 0.0001 22.3 5.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EAU90587.2 - 0.0009 19.1 6.3 0.0009 19.1 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU90587.2 - 0.0069 16.3 6.4 0.0069 16.3 6.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAU90587.2 - 0.0089 16.1 3.7 0.018 15.1 3.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EAU90587.2 - 0.043 13.6 6.3 0.1 12.4 6.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CSN5_C PF18323.1 EAU90587.2 - 0.061 14.3 6.8 0.049 14.5 4.7 2.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain zf-UBP_var PF17807.1 EAU90587.2 - 0.21 11.3 1.3 0.47 10.2 1.3 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger DUF2935 PF11155.8 EAU90587.2 - 1.2 9.5 4.1 3.3 8.1 2.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Prok-RING_4 PF14447.6 EAU90587.2 - 2.2 8.2 19.9 0.85 9.5 10.5 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 SLATT_5 PF18160.1 EAU90587.2 - 2.4 7.4 4.1 3.8 6.8 3.7 1.5 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Cnn_1N PF07989.11 EAU90587.2 - 7.3 6.8 15.2 11 6.2 1.2 2.8 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 EAU90587.2 - 7.5 5.8 11.7 13 5.1 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Polysacc_deac_1 PF01522.21 EAU90589.1 - 2.2e-19 69.6 0.1 4.2e-19 68.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase SH3_1 PF00018.28 EAU90591.1 - 2.5e-18 65.4 2.9 1.3e-08 34.3 0.2 2.8 2 1 0 2 2 2 2 SH3 domain SAM_1 PF00536.30 EAU90591.1 - 6.4e-16 58.5 0.1 1.4e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EAU90591.1 - 2.1e-14 53.3 0.0 4.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EAU90591.1 - 1.8e-13 50.1 1.3 9.7e-06 25.4 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EAU90591.1 - 5.8e-07 29.1 0.4 3.1e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 Variant SH3 domain RA PF00788.23 EAU90591.1 - 2.6e-05 24.7 0.0 5.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 EAU90591.1 - 0.0055 17.0 4.3 0.29 11.4 0.4 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain SAM_PNT PF02198.16 EAU90591.1 - 0.0087 16.0 0.0 0.057 13.4 0.0 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Glyco_hydro_43 PF04616.14 EAU90593.2 - 3.9e-48 164.2 1.3 4.8e-48 163.9 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DnaJ PF00226.31 EAU90594.2 - 3.7e-21 75.0 4.1 7.2e-21 74.1 4.1 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 EAU90595.2 - 9.5e-10 38.9 3.1 0.035 15.0 0.6 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU90595.2 - 1.4e-06 28.5 0.4 0.19 12.0 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAU90595.2 - 0.0026 16.5 0.1 0.023 13.3 0.0 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF1192 PF06698.11 EAU90595.2 - 0.0039 17.2 0.0 0.0079 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Coatomer_WDAD PF04053.14 EAU90595.2 - 0.17 10.9 0.0 0.48 9.4 0.0 1.7 2 0 0 2 2 2 0 Coatomer WD associated region IBR PF01485.21 EAU90596.1 - 6.1e-08 32.8 24.3 0.00021 21.5 2.6 3.6 3 1 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EAU90596.1 - 0.0028 18.0 6.6 0.0028 18.0 6.6 4.3 2 1 2 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 EAU90596.1 - 0.0053 16.7 5.1 0.0053 16.7 5.1 3.7 2 1 1 3 3 2 1 zinc-RING finger domain Cys_rich_KTR PF14205.6 EAU90596.1 - 0.015 15.1 0.7 0.015 15.1 0.7 3.7 3 1 0 4 4 4 0 Cysteine-rich KTR zf-tcix PF14952.6 EAU90596.1 - 0.043 13.4 0.9 0.043 13.4 0.9 2.3 2 0 0 2 2 1 0 Putative treble-clef, zinc-finger, Zn-binding GFA PF04828.14 EAU90596.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.1 2 2 2 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf-TFIIB PF13453.6 EAU90596.1 - 1.9 7.9 10.6 1.2 8.6 1.5 3.6 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-ribbon_3 PF13248.6 EAU90596.1 - 2 8.0 13.5 5 6.7 0.1 4.9 4 1 0 4 4 4 0 zinc-ribbon domain zf-C3HC4_4 PF15227.6 EAU90596.1 - 5 7.4 28.7 0.093 12.9 2.2 5.1 4 1 0 5 5 5 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EAU90596.1 - 9 6.4 22.3 0.24 11.4 1.1 3.6 3 0 0 3 3 3 0 RING-type zinc-finger zf_UBZ PF18439.1 EAU90596.1 - 9.6 5.9 14.1 2.9 7.6 0.2 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-RING_2 PF13639.6 EAU90597.1 - 3.3e-07 30.5 10.2 6.9e-07 29.5 10.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAU90597.1 - 3.5e-07 30.0 12.4 4.8e-07 29.5 11.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU90597.1 - 3.1e-05 23.8 11.1 9.7e-05 22.2 11.1 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU90597.1 - 3.6e-05 23.7 6.0 3.6e-05 23.7 6.0 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EAU90597.1 - 0.00097 18.8 9.1 0.0021 17.7 9.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EAU90597.1 - 0.0021 17.9 9.2 0.0047 16.7 9.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU90597.1 - 0.0049 16.7 6.5 0.017 15.0 6.5 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EAU90597.1 - 0.006 16.4 14.4 0.006 16.4 14.4 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU90597.1 - 0.025 14.7 8.0 0.085 13.0 8.0 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 EAU90597.1 - 0.045 14.0 1.1 0.045 14.0 1.1 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Baculo_IE-1 PF05290.11 EAU90597.1 - 0.072 13.0 2.5 0.11 12.5 2.5 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UBP_var PF17807.1 EAU90597.1 - 0.13 12.0 4.6 0.24 11.2 4.6 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger zf-rbx1 PF12678.7 EAU90597.1 - 0.16 12.3 10.4 0.093 13.0 8.2 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-UDP PF14569.6 EAU90597.1 - 0.2 11.8 3.8 0.43 10.7 3.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EAU90597.1 - 0.94 9.4 4.5 3.9 7.4 4.5 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein PQ-loop PF04193.14 EAU90598.2 - 1.9e-12 46.7 1.7 3e-12 46.1 1.7 1.3 1 0 0 1 1 1 1 PQ loop repeat ER_lumen_recept PF00810.18 EAU90598.2 - 0.00048 21.0 2.0 0.0005 20.9 0.7 1.6 1 1 0 1 1 1 1 ER lumen protein retaining receptor L_HMGIC_fpl PF10242.9 EAU90598.2 - 0.016 15.4 0.5 0.03 14.5 0.5 1.4 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein SLATT_5 PF18160.1 EAU90598.2 - 1.3 8.3 2.9 0.77 9.1 0.3 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Tmemb_14 PF03647.13 EAU90599.2 - 3.1e-18 66.3 5.3 3.6e-18 66.1 5.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C SIR2 PF02146.17 EAU90600.2 - 2.9e-28 99.0 0.0 4.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Kei1 PF08552.11 EAU90601.2 - 1.1e-24 87.4 5.0 4e-24 85.6 4.1 2.1 1 1 1 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 IF4E PF01652.18 EAU90602.1 - 1e-53 181.4 0.0 1.3e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SelR PF01641.18 EAU90603.1 - 2.4e-54 182.6 0.1 2.7e-54 182.4 0.1 1.0 1 0 0 1 1 1 1 SelR domain ADD_ATRX PF17981.1 EAU90603.1 - 0.0026 17.6 0.1 0.061 13.2 0.0 2.2 2 0 0 2 2 2 1 Cysteine Rich ADD domain zf-Mss51 PF13824.6 EAU90603.1 - 0.013 15.6 3.3 0.11 12.7 1.0 3.0 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.14 EAU90603.1 - 0.02 15.2 0.6 0.45 10.9 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27e PF01667.17 EAU90603.1 - 0.021 14.5 0.4 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 Yippee-Mis18 PF03226.14 EAU90603.1 - 0.028 14.6 0.4 0.088 13.0 0.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_10 PF10058.9 EAU90603.1 - 0.091 12.5 0.1 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 EAU90603.1 - 0.13 12.3 3.5 1 9.5 2.1 2.2 1 1 2 3 3 3 0 Double zinc ribbon Ribosomal_L37e PF01907.19 EAU90603.1 - 0.35 11.0 3.6 4 7.7 0.8 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zf-ACC PF17848.1 EAU90603.1 - 0.43 10.7 2.3 2.6 8.2 0.3 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-ribbon_3 PF13248.6 EAU90603.1 - 0.91 9.0 6.5 6.8 6.3 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 EAU90603.1 - 2.9 7.7 4.8 6.5 6.5 0.4 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF2408 PF10303.9 EAU90605.2 - 1.4e-50 171.3 10.8 1.2e-36 126.2 1.6 5.2 5 0 0 5 5 5 4 Protein of unknown function (DUF2408) RPN7 PF10602.9 EAU90605.2 - 0.0028 17.4 0.2 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 26S proteasome subunit RPN7 V-SNARE PF05008.15 EAU90605.2 - 0.061 13.7 0.1 0.061 13.7 0.1 4.0 5 1 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus ATG16 PF08614.11 EAU90605.2 - 1.1 9.4 6.6 1.5 9.0 0.2 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4208 PF13907.6 EAU90605.2 - 2.2 8.8 5.8 8.3 6.9 0.7 4.2 3 1 2 5 5 5 0 Domain of unknown function (DUF4208) Voltage_CLC PF00654.20 EAU90606.2 - 8.8e-13 48.2 19.6 1.2e-08 34.6 5.9 4.7 3 2 1 4 4 4 3 Voltage gated chloride channel CBS PF00571.28 EAU90606.2 - 3.6e-07 30.5 0.1 1.5e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 CBS domain Med28 PF11594.8 EAU90606.2 - 0.18 11.9 0.2 0.39 10.8 0.1 1.5 2 0 0 2 2 2 0 Mediator complex subunit 28 Med4 PF10018.9 EAU90607.2 - 2.3e-20 73.1 0.1 3.1e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4665 PF15679.5 EAU90607.2 - 0.0073 16.9 0.1 0.011 16.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4665) CortBP2 PF09727.9 EAU90607.2 - 0.051 13.5 1.9 0.077 12.9 1.9 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 FH2 PF02181.23 EAU90607.2 - 0.093 11.8 0.2 0.12 11.5 0.2 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain CENP-H PF05837.12 EAU90607.2 - 0.14 12.6 2.0 0.22 11.9 2.0 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DSPc PF00782.20 EAU90608.1 - 5e-30 104.0 0.0 7.1e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAU90608.1 - 9.8e-06 25.3 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EAU90608.1 - 0.0079 16.5 0.6 0.016 15.5 0.1 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase2 PF03162.13 EAU90608.1 - 0.04 13.5 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPn PF14671.6 EAU90608.1 - 0.08 13.4 0.0 0.24 11.8 0.0 1.8 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half CDC37_M PF08565.11 EAU90608.1 - 0.11 12.4 0.1 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain NADH-u_ox-rdase PF10785.9 EAU90611.1 - 2.7e-34 117.7 0.7 3.7e-34 117.2 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EAU90611.1 - 6.3e-14 51.7 0.0 9.3e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF2530 PF10745.9 EAU90611.1 - 0.011 15.9 0.2 0.017 15.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF3943 PF13084.6 EAU90611.1 - 0.31 10.9 1.3 12 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) zf-RanBP PF00641.18 EAU90612.1 - 1e-07 31.1 36.3 8.5e-06 25.0 4.7 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others PHD_2 PF13831.6 EAU90612.1 - 0.61 9.7 5.2 41 3.8 0.2 3.5 3 0 0 3 3 3 0 PHD-finger zf-Sec23_Sec24 PF04810.15 EAU90612.1 - 1.8 8.7 9.6 2.8 8.1 0.0 3.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Pkinase PF00069.25 EAU90613.1 - 2.4e-73 246.8 0.0 2.8e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU90613.1 - 5.9e-31 107.7 0.0 2e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EAU90613.1 - 0.0069 16.3 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU90613.1 - 0.018 14.4 0.1 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 EAU90613.1 - 0.018 14.0 0.2 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain DnaJ PF00226.31 EAU90614.1 - 2.1e-19 69.4 1.3 5.4e-19 68.1 1.3 1.7 2 0 0 2 2 2 1 DnaJ domain Couple_hipA PF13657.6 EAU90614.1 - 0.18 12.5 0.7 0.43 11.2 0.2 1.9 2 1 0 2 2 2 0 HipA N-terminal domain CCER1 PF15482.6 EAU90614.1 - 1.5 8.6 5.0 2.8 7.8 5.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 OHCU_decarbox PF09349.10 EAU90615.1 - 8.8e-31 107.5 0.0 1.2e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase GFO_IDH_MocA PF01408.22 EAU90616.1 - 1e-19 71.5 0.1 1.5e-19 71.0 0.1 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold IBR PF01485.21 EAU90619.2 - 3.8e-09 36.6 23.5 1.5e-07 31.6 5.3 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EAU90619.2 - 3e-06 27.0 5.7 3e-06 27.0 5.7 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU90619.2 - 4.8e-06 26.4 4.7 4.8e-06 26.4 4.7 4.1 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU90619.2 - 2.6e-05 24.2 0.8 2.6e-05 24.2 0.8 4.7 4 2 1 5 5 5 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAU90619.2 - 4.9e-05 23.6 6.6 4.9e-05 23.6 6.6 4.1 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU90619.2 - 0.00027 20.7 7.7 0.00027 20.7 7.7 5.1 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU90619.2 - 0.0097 16.1 3.7 0.0097 16.1 3.7 4.6 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EAU90619.2 - 0.013 15.2 3.9 0.013 15.2 3.9 2.8 3 0 0 3 3 3 0 RING-like zinc finger DUF3795 PF12675.7 EAU90619.2 - 1 9.8 19.9 1.1 9.7 11.8 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) zf-RING_5 PF14634.6 EAU90620.2 - 0.00015 21.6 7.3 0.0003 20.7 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EAU90620.2 - 0.0011 18.8 6.7 0.0032 17.3 6.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU90620.2 - 0.023 15.0 8.7 0.076 13.4 8.8 1.9 1 1 1 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 EAU90620.2 - 0.035 14.1 4.9 0.1 12.7 4.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAU90620.2 - 0.74 9.7 9.0 0.1 12.4 3.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EAU90620.2 - 0.82 9.5 4.6 1.6 8.6 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.12 EAU90620.2 - 1.7 8.3 4.5 7.8 6.1 0.5 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C3HC4_4 PF15227.6 EAU90620.2 - 2.3 8.5 9.0 0.093 12.9 2.9 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CHAT PF12770.7 EAU90623.1 - 2.8e-26 92.6 0.0 3e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 CHAT domain F-box-like PF12937.7 EAU90624.2 - 1e-08 34.9 2.3 0.002 18.0 0.2 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EAU90624.2 - 0.11 12.4 1.9 1.1 9.2 0.2 2.9 2 0 0 2 2 2 0 F-box domain zf-MYND PF01753.18 EAU90625.1 - 6.8e-12 45.3 10.4 1e-11 44.7 10.4 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU90625.1 - 2.4 8.5 6.7 4.6 7.6 6.7 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CBS PF00571.28 EAU90626.1 - 0.0028 18.1 0.0 0.0058 17.1 0.0 1.6 1 0 0 1 1 1 1 CBS domain Lipase_3 PF01764.25 EAU90628.1 - 1.2e-21 77.1 0.0 1.7e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAU90628.1 - 0.0028 18.3 2.7 0.004 17.8 2.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EAU90628.1 - 0.0094 15.7 0.2 0.013 15.3 0.2 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EAU90628.1 - 0.04 13.8 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAU90628.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 EAU90628.1 - 0.14 11.8 0.6 0.22 11.1 0.6 1.2 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 EAU90628.1 - 0.2 11.2 0.2 0.33 10.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF1899 PF08953.11 EAU90628.1 - 0.25 11.2 0.8 5.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) PAF-AH_p_II PF03403.13 EAU90628.1 - 0.27 9.7 0.2 0.36 9.3 0.2 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Podoplanin PF05808.11 EAU90629.1 - 0.015 15.4 4.0 0.036 14.2 4.0 1.6 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.20 EAU90629.1 - 0.23 11.4 0.0 0.44 10.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Yip1 PF04893.17 EAU90629.1 - 1.6 8.4 3.4 3.3 7.4 3.4 1.4 1 1 0 1 1 1 0 Yip1 domain F-box-like PF12937.7 EAU90630.2 - 1.7e-10 40.6 2.6 4.8e-10 39.2 2.6 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU90632.2 - 4.3e-10 39.3 2.6 5.6e-10 39.0 1.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU90632.2 - 0.32 10.9 2.1 7.4 6.6 0.1 3.0 2 1 0 2 2 2 0 F-box domain 4HBT_2 PF13279.6 EAU90634.2 - 1.4e-13 51.4 0.0 2.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EAU90634.2 - 3.1e-07 30.6 0.0 6.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EAU90634.2 - 0.01 15.2 0.0 0.025 13.9 0.0 1.7 2 0 0 2 2 2 0 Acyl-ACP thioesterase AMP-binding PF00501.28 EAU90635.2 - 2.6e-45 154.8 0.0 3.7e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EAU90635.2 - 2.8e-10 40.4 0.2 7.1e-10 39.1 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep PF00132.24 EAU90635.2 - 4.2e-10 38.9 0.7 0.00036 20.1 0.1 6.2 7 1 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 EAU90635.2 - 8e-08 33.2 0.0 0.0047 17.9 0.1 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain zf-C3HC4 PF00097.25 EAU90635.2 - 0.0051 16.7 2.9 0.013 15.4 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU90635.2 - 0.0058 16.5 3.3 0.012 15.4 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU90635.2 - 0.0083 16.0 5.3 0.0088 15.9 3.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU90635.2 - 0.023 14.6 2.3 0.047 13.6 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EAU90635.2 - 0.024 14.6 0.7 0.06 13.3 0.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain GH3 PF03321.13 EAU90635.2 - 0.16 10.8 0.0 2.5 6.8 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter zf-RING_UBOX PF13445.6 EAU90635.2 - 0.33 11.0 2.0 0.87 9.7 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF202 PF02656.15 EAU90637.2 - 0.068 13.6 0.5 0.11 13.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Ubiquitin_2 PF14560.6 EAU90638.1 - 3.7e-27 94.6 0.0 6.6e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 EAU90638.1 - 9.9e-27 92.8 2.4 1.7e-26 92.0 2.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 EAU90638.1 - 0.0017 18.1 0.0 0.0052 16.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family AAA PF00004.29 EAU90639.1 - 2.6e-96 319.1 0.0 9.5e-47 158.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU90639.1 - 2.7e-26 91.1 9.2 8.1e-13 48.0 1.0 3.0 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EAU90639.1 - 3.1e-19 68.9 0.1 1.6e-18 66.6 0.2 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EAU90639.1 - 5.7e-14 52.2 0.2 1.6e-05 24.7 0.0 3.3 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EAU90639.1 - 1.6e-13 51.1 0.0 1.5e-07 31.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EAU90639.1 - 9.3e-12 45.3 0.0 5.3e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EAU90639.1 - 2.8e-11 43.0 0.0 6.2e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 EAU90639.1 - 4.9e-11 42.8 0.2 3.3e-05 23.9 0.1 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU90639.1 - 2.7e-10 40.9 0.3 0.00086 19.7 0.0 4.3 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.13 EAU90639.1 - 3.1e-09 36.5 0.1 0.0017 17.6 0.0 2.4 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EAU90639.1 - 8.9e-09 35.7 0.1 0.054 13.8 0.0 3.9 2 2 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EAU90639.1 - 1.1e-08 35.0 0.4 3.1e-07 30.3 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EAU90639.1 - 4e-07 30.6 0.0 0.017 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EAU90639.1 - 4.3e-07 29.5 0.3 0.028 13.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EAU90639.1 - 4.8e-07 29.7 0.0 0.026 14.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EAU90639.1 - 1.5e-06 28.5 0.0 0.023 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EAU90639.1 - 2.1e-06 27.8 0.0 0.024 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EAU90639.1 - 3e-06 26.9 0.1 0.016 14.7 0.0 2.9 3 1 0 3 3 2 2 P-loop containing dynein motor region ATPase PF06745.13 EAU90639.1 - 3.7e-06 26.5 0.2 0.85 8.9 0.0 3.4 3 0 0 3 3 3 2 KaiC Parvo_NS1 PF01057.17 EAU90639.1 - 1.2e-05 24.6 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EAU90639.1 - 1.5e-05 25.3 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EAU90639.1 - 2.5e-05 23.9 2.5 1.1 8.8 0.1 3.6 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EAU90639.1 - 2.8e-05 23.9 0.0 0.46 10.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EAU90639.1 - 3.8e-05 24.2 0.0 0.23 12.0 0.0 3.6 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 EAU90639.1 - 4.7e-05 23.2 0.1 0.44 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 EAU90639.1 - 7.2e-05 22.1 0.0 0.021 14.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EAU90639.1 - 0.00012 22.0 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein PhoH PF02562.16 EAU90639.1 - 0.00012 21.6 0.3 0.5 9.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 EAU90639.1 - 0.00017 22.1 0.0 0.91 10.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.11 EAU90639.1 - 0.00029 20.7 0.0 0.82 9.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EAU90639.1 - 0.00034 20.6 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EAU90639.1 - 0.00039 20.5 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EAU90639.1 - 0.0011 18.3 0.0 0.55 9.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EAU90639.1 - 0.0019 18.0 1.9 0.96 9.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 EAU90639.1 - 0.0024 17.7 0.0 0.28 10.9 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EAU90639.1 - 0.0034 17.1 0.4 2.6 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EAU90639.1 - 0.0038 17.2 0.1 4.9 7.0 0.0 3.2 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EAU90639.1 - 0.0051 16.9 0.0 3.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EAU90639.1 - 0.0062 15.8 0.0 3.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 EAU90639.1 - 0.0068 16.3 0.1 1.5 8.7 0.0 2.9 3 0 0 3 3 3 1 NACHT domain T2SSE PF00437.20 EAU90639.1 - 0.01 14.9 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 EAU90639.1 - 0.011 16.1 2.9 4.4 7.6 0.0 3.6 3 1 0 4 4 3 0 AAA domain UFD1 PF03152.14 EAU90639.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 NB-ARC PF00931.22 EAU90639.1 - 0.015 14.5 0.0 0.73 9.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EAU90639.1 - 0.036 14.0 0.4 6.5 6.6 0.0 3.4 3 0 0 3 3 3 0 NTPase IPT PF01745.16 EAU90639.1 - 0.037 13.4 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Molydop_binding PF01568.21 EAU90639.1 - 0.039 14.0 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Cytidylate_kin PF02224.18 EAU90639.1 - 0.046 13.5 0.0 7.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 EAU90639.1 - 0.046 12.9 0.0 0.5 9.6 0.0 2.3 2 1 1 3 3 3 0 KAP family P-loop domain PIF1 PF05970.14 EAU90639.1 - 0.11 11.6 0.0 8.5 5.4 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase Zot PF05707.12 EAU90639.1 - 0.21 11.2 0.0 7.4 6.2 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Hydin_ADK PF17213.3 EAU90639.1 - 1.4 9.2 3.8 39 4.4 0.0 3.6 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain DAGAT PF03982.13 EAU90640.2 - 3.4e-102 341.3 0.0 4.5e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF5308 PF17233.2 EAU90640.2 - 0.08 13.2 3.3 0.12 12.6 3.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF3464 PF11947.8 EAU90640.2 - 0.12 12.1 1.4 0.22 11.3 1.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Cut8 PF08559.10 EAU90640.2 - 0.46 10.1 5.6 0.99 9.0 5.6 1.5 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein F-box-like PF12937.7 EAU90641.1 - 0.00027 20.8 0.0 0.00063 19.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU90642.1 - 0.0007 19.4 0.4 0.0007 19.4 0.4 2.3 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EAU90642.1 - 0.19 12.2 4.8 5.7 7.5 0.5 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Lipase_3 PF01764.25 EAU90643.1 - 3.6e-24 85.3 0.0 5.2e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EAU90643.1 - 0.00057 19.7 0.0 0.00087 19.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EAU90643.1 - 0.0012 19.5 1.8 0.002 18.8 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EAU90643.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 EAU90643.1 - 0.018 14.6 0.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EAU90643.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EAU90643.1 - 0.06 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.20 EAU90643.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Pkinase_fungal PF17667.1 EAU90644.2 - 5.3e-55 186.8 0.3 1.4e-33 116.3 0.1 3.1 1 1 1 2 2 2 2 Fungal protein kinase Kdo PF06293.14 EAU90644.2 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EAU90644.2 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Gag_p12 PF01141.18 EAU90644.2 - 0.85 10.0 5.1 0.87 10.0 0.2 2.8 2 1 1 3 3 3 0 Gag polyprotein, inner coat protein p12 STT3 PF02516.14 EAU90645.1 - 3.8e-149 497.8 32.5 3.3e-143 478.2 28.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit LRR_4 PF12799.7 EAU90647.2 - 0.79 10.2 7.9 28 5.3 1.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) p450 PF00067.22 EAU90649.2 - 3.4e-35 121.7 0.1 9.7e-22 77.3 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 Ovate PF04844.13 EAU90649.2 - 0.037 14.0 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Transcriptional repressor, ovate Hirudin PF00713.17 EAU90649.2 - 0.054 13.8 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Hirudin TPR_MLP1_2 PF07926.12 EAU90652.2 - 0.025 14.6 1.0 0.039 14.0 1.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein VPS11_C PF12451.8 EAU90652.2 - 0.14 12.4 0.4 0.33 11.2 0.4 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal CE2_N PF17996.1 EAU90653.2 - 0.0015 18.5 0.0 0.59 10.1 0.0 2.8 2 1 0 2 2 2 2 Carbohydrate esterase 2 N-terminal CE2_N PF17996.1 EAU90654.2 - 0.0023 17.9 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Podoplanin PF05808.11 EAU90654.2 - 0.019 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Podoplanin PTP_tm PF18861.1 EAU90654.2 - 0.034 14.1 0.2 0.059 13.4 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Rick_17kDa_Anti PF05433.15 EAU90654.2 - 0.21 11.5 2.8 0.49 10.3 2.8 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EAU90654.2 - 0.39 10.7 2.0 0.8 9.8 2.0 1.5 1 0 0 1 1 1 0 Glycine zipper Lipase_3 PF01764.25 EAU90656.1 - 3.2e-21 75.7 0.0 4.3e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAU90656.1 - 0.001 19.8 0.7 0.001 19.8 0.7 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU90656.1 - 0.0017 18.0 0.0 0.0032 17.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAU90656.1 - 0.018 14.3 0.1 0.038 13.2 0.1 1.4 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EAU90656.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EAU90656.1 - 0.094 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Mt_ATP-synt_B PF05405.14 EAU90657.1 - 1.1e-43 148.7 10.6 1.3e-43 148.4 10.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2526 PF10735.9 EAU90657.1 - 0.012 15.8 1.0 0.025 14.7 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) DUF4004 PF13171.6 EAU90657.1 - 0.042 14.1 3.3 0.065 13.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) DUF5623 PF18536.1 EAU90657.1 - 0.071 13.4 0.9 0.18 12.1 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5623) DUF1539 PF07560.11 EAU90657.1 - 0.094 12.8 1.7 0.12 12.5 0.8 1.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) CUT PF02376.15 EAU90657.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 CUT domain TFIIA PF03153.13 EAU90659.1 - 0.012 15.6 17.7 0.015 15.4 17.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 EAU90659.1 - 7.7 3.5 16.9 9.3 3.2 16.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RCC1 PF00415.18 EAU90663.2 - 3.7e-45 152.3 9.8 9.7e-11 42.1 0.0 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAU90663.2 - 1e-18 66.6 28.0 7.8e-07 28.7 0.6 6.5 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 EAU90663.2 - 4.6e-09 36.0 6.7 4.6e-09 36.0 6.7 2.0 2 0 0 2 2 2 1 PHD-finger C1_2 PF03107.16 EAU90663.2 - 0.018 15.4 0.5 0.018 15.4 0.5 2.0 2 0 0 2 2 2 0 C1 domain Reg_prop PF07494.11 EAU90663.2 - 0.11 12.7 0.3 24 5.6 0.1 3.2 2 0 0 2 2 2 0 Two component regulator propeller PBP1_TM PF14812.6 EAU90663.2 - 0.72 10.3 6.5 1.3 9.4 6.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MULE PF10551.9 EAU90664.2 - 7e-11 42.4 0.1 1.5e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 MULE transposase domain Radical_SAM_C PF16199.5 EAU90664.2 - 0.052 13.6 0.2 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Radical_SAM C-terminal domain LEAP-2 PF07359.11 EAU90664.2 - 0.11 12.3 0.1 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) F-box PF00646.33 EAU90666.1 - 0.00027 20.7 0.8 0.5 10.3 0.1 2.9 2 1 0 2 2 2 2 F-box domain F-box-like PF12937.7 EAU90666.1 - 0.0015 18.4 0.1 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 EAU90666.1 - 0.36 11.5 1.4 2.1 9.2 0.4 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat Cu-oxidase PF00394.22 EAU90667.2 - 5.6e-44 150.1 0.1 3.8e-41 140.9 0.0 2.9 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU90667.2 - 3.5e-38 130.4 7.4 1.3e-36 125.3 0.1 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU90667.2 - 7.9e-35 119.4 0.5 9.2e-33 112.8 0.2 3.3 3 1 0 3 3 3 1 Multicopper oxidase Hjc PF01870.18 EAU90667.2 - 0.16 12.0 0.1 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) tRNA_NucTransf2 PF09249.11 EAU90667.2 - 0.19 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain F-box-like PF12937.7 EAU90669.2 - 4.4e-08 32.9 0.6 4.4e-08 32.9 0.6 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EAU90669.2 - 0.00091 19.6 11.4 14 6.3 0.0 5.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) Kei1 PF08552.11 EAU90670.1 - 0.037 13.9 0.0 0.039 13.8 0.0 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Cu-oxidase PF00394.22 EAU90671.2 - 6.1e-42 143.4 0.1 3.4e-39 134.5 0.0 2.9 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU90671.2 - 3.3e-32 111.1 6.3 5.6e-31 107.1 0.0 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU90671.2 - 9.2e-31 106.3 0.5 4.8e-30 104.0 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase GMC_oxred_N PF00732.19 EAU90672.2 - 6e-64 216.3 0.0 9e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU90672.2 - 2e-23 83.5 0.0 3.3e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU90672.2 - 0.00029 21.0 0.2 0.0038 17.4 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EAU90672.2 - 0.0025 17.0 0.8 0.26 10.3 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EAU90672.2 - 0.0029 16.7 0.2 0.0043 16.1 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein WD40 PF00400.32 EAU90674.2 - 1e-31 108.4 30.3 3.7e-08 33.9 0.3 8.6 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU90674.2 - 1e-14 54.6 1.4 0.0051 17.1 0.0 6.4 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAU90674.2 - 1.9e-06 27.4 0.0 0.0048 16.3 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 EAU90674.2 - 0.00023 19.9 0.8 0.21 10.2 0.0 3.2 1 1 2 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EAU90674.2 - 0.0015 18.2 0.7 0.077 12.6 0.1 2.8 2 1 0 2 2 2 1 PQQ-like domain F-box-like PF12937.7 EAU90674.2 - 0.0059 16.5 0.1 0.019 14.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like BBS2_Mid PF14783.6 EAU90674.2 - 0.16 12.0 0.0 4.4 7.4 0.0 2.9 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EAU90674.2 - 0.17 12.4 14.5 4.7 7.8 0.1 5.6 5 1 0 5 5 5 0 PQQ-like domain PQQ PF01011.21 EAU90674.2 - 4.2 7.5 5.5 13 5.9 0.2 4.2 4 0 0 4 4 4 0 PQQ enzyme repeat Methyltransf_15 PF09445.10 EAU90675.1 - 4.9e-36 123.8 0.0 1.7e-35 122.0 0.0 1.7 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EAU90675.1 - 5.3e-07 30.3 0.0 1.1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EAU90675.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EAU90675.1 - 0.00015 21.6 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EAU90675.1 - 0.00073 19.2 0.0 0.0055 16.4 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EAU90675.1 - 0.00074 20.1 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EAU90675.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.18 EAU90675.1 - 0.018 14.8 0.2 0.19 11.4 0.2 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 EAU90675.1 - 0.022 14.2 0.1 0.034 13.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EAU90675.1 - 0.028 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DNA_pol3_theta PF06440.11 EAU90675.1 - 0.14 11.8 0.6 0.28 10.9 0.6 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit GMC_oxred_N PF00732.19 EAU90676.2 - 1.7e-40 139.2 2.6 1.5e-27 96.8 0.2 2.4 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU90676.2 - 5.8e-24 85.3 0.0 1.3e-23 84.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EAU90676.2 - 0.0032 17.7 0.0 0.009 16.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EAU90676.2 - 0.1 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Rit1_C PF17184.4 EAU90676.2 - 0.13 11.7 0.7 0.19 11.1 0.7 1.2 1 0 0 1 1 1 0 Rit1 N-terminal domain Cu-oxidase PF00394.22 EAU90677.1 - 1.9e-47 161.3 0.0 1.1e-43 149.1 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU90677.1 - 1.1e-35 122.3 5.1 6.8e-34 116.6 0.1 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU90677.1 - 2.7e-34 117.7 1.5 2.9e-33 114.4 0.0 3.0 3 1 0 3 3 3 1 Multicopper oxidase RRM_1 PF00076.22 EAU90678.2 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EAU90679.2 - 6.2e-08 32.5 0.0 2.3e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAD_binding_3 PF01494.19 EAU90680.2 - 4.8e-24 85.3 0.0 7.9e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EAU90680.2 - 0.00015 21.9 0.4 0.00043 20.4 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EAU90680.2 - 0.00061 19.1 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EAU90680.2 - 0.0073 15.2 0.2 0.021 13.7 0.1 1.8 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EAU90680.2 - 0.012 14.8 0.2 0.17 11.1 0.3 2.0 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU90680.2 - 0.015 14.9 1.3 0.043 13.4 0.9 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 EAU90680.2 - 0.092 11.8 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Peptidase_M28 PF04389.17 EAU90683.2 - 7.4e-37 127.0 0.1 1.4e-36 126.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Mo25 PF08569.11 EAU90683.2 - 0.25 10.7 0.0 0.78 9.0 0.0 1.7 1 1 0 2 2 2 0 Mo25-like Aminotran_5 PF00266.19 EAU90685.1 - 6.3e-46 157.0 0.0 8e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EAU90685.1 - 0.0044 16.2 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II IBR PF01485.21 EAU90686.2 - 7.2e-16 58.2 33.3 1.5e-08 34.7 9.5 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EAU90686.2 - 2.6e-07 30.6 4.6 2.6e-07 30.6 4.6 2.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAU90686.2 - 6.1e-07 29.2 1.5 6.1e-07 29.2 1.5 3.4 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU90686.2 - 6.5e-07 29.1 2.8 6.5e-07 29.1 2.8 3.7 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU90686.2 - 3.1e-05 24.2 3.7 3.1e-05 24.2 3.7 3.5 3 0 0 3 3 2 1 Ring finger domain zf_CCCH_4 PF18345.1 EAU90686.2 - 0.00013 21.9 4.8 0.00028 20.8 4.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_3 PF13920.6 EAU90686.2 - 0.00013 21.7 2.9 0.00013 21.7 2.9 4.1 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU90686.2 - 0.00013 22.0 6.2 0.00013 22.0 6.2 3.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING RRM_1 PF00076.22 EAU90686.2 - 0.00038 20.2 0.2 2.5 8.0 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 EAU90686.2 - 0.00043 20.1 2.1 0.0011 18.9 2.1 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EAU90686.2 - 0.001 18.8 4.9 0.001 18.8 4.9 2.0 2 0 0 2 2 1 1 CCCH-type zinc finger zf-RING_5 PF14634.6 EAU90686.2 - 0.0013 18.6 4.7 0.0013 18.6 4.7 3.7 3 1 0 3 3 2 1 zinc-RING finger domain DUF1039 PF06287.11 EAU90686.2 - 0.21 12.0 2.0 3.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) Ank_2 PF12796.7 EAU90687.2 - 2.7e-32 111.2 0.3 6.1e-09 36.4 0.0 5.7 5 2 2 7 7 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 EAU90687.2 - 2.6e-29 100.4 1.5 0.0001 22.6 0.0 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EAU90687.2 - 6.7e-29 99.6 3.1 4.1e-06 27.0 0.1 6.7 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU90687.2 - 3.5e-27 94.4 0.5 1.7e-06 28.5 0.0 6.6 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90687.2 - 6.1e-25 84.6 1.0 0.003 17.9 0.0 8.9 8 1 0 8 8 7 6 Ankyrin repeat AAA_22 PF13401.6 EAU90687.2 - 9.8e-05 22.6 0.0 0.00029 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90687.2 - 0.00014 21.9 0.1 0.00056 19.9 0.0 2.2 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 EAU90687.2 - 0.0074 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EAU90687.2 - 0.0083 16.5 0.2 0.055 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain NapD PF03927.13 EAU90687.2 - 0.099 12.7 0.1 1.3 9.2 0.1 2.8 2 1 1 3 3 3 0 NapD protein AAA_18 PF13238.6 EAU90687.2 - 0.1 13.1 0.1 0.51 10.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain TPR_1 PF00515.28 EAU90688.2 - 8.8e-28 95.0 1.3 9.1e-06 25.3 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAU90688.2 - 6.9e-26 88.2 7.1 0.00085 19.3 0.1 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat DnaJ PF00226.31 EAU90688.2 - 1.5e-22 79.5 0.3 3.3e-22 78.4 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_9 PF13371.6 EAU90688.2 - 8e-22 77.2 3.4 1.4e-06 28.4 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAU90688.2 - 6.5e-21 73.7 0.7 9.7e-08 31.6 0.3 6.5 6 1 1 7 7 7 4 TPR repeat TPR_16 PF13432.6 EAU90688.2 - 9.3e-19 67.8 11.6 3.8e-07 30.6 0.1 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90688.2 - 2.1e-13 49.9 14.6 0.012 16.4 0.0 7.6 5 3 3 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90688.2 - 4.9e-13 48.2 0.1 0.85 10.0 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EAU90688.2 - 2.7e-11 43.6 10.6 1.3 9.4 0.0 7.5 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAU90688.2 - 2.2e-10 40.9 13.4 0.0034 17.8 0.2 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAU90688.2 - 2.7e-06 27.6 3.6 0.16 12.7 0.0 6.1 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU90688.2 - 4e-06 26.8 4.4 0.57 10.7 0.2 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU90688.2 - 5.5e-06 26.5 3.6 0.28 11.4 0.0 4.7 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EAU90688.2 - 5.3e-05 22.7 0.1 0.029 13.8 0.0 3.2 2 1 1 3 3 3 1 MalT-like TPR region Fis1_TPR_C PF14853.6 EAU90688.2 - 6e-05 23.0 4.6 0.067 13.3 0.0 4.4 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EAU90688.2 - 0.00075 19.5 6.4 0.23 11.5 0.2 4.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EAU90688.2 - 0.0019 18.1 1.2 25 5.2 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU90688.2 - 0.0086 15.9 5.4 0.57 10.1 0.1 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat FapA PF03961.13 EAU90688.2 - 0.2 10.2 3.3 0.16 10.6 0.9 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A FliJ PF02050.16 EAU90688.2 - 0.34 11.1 3.4 1.4 9.2 0.2 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein SHNi-TPR PF10516.9 EAU90688.2 - 3.9 7.0 6.7 12 5.4 0.1 4.4 5 0 0 5 5 5 0 SHNi-TPR FIVAR PF07554.13 EAU90688.2 - 6 7.7 7.8 2.3 9.1 2.6 2.5 2 0 0 2 2 2 0 FIVAR domain DUF4834 PF16118.5 EAU90689.2 - 0.00024 22.0 4.1 0.0034 18.3 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4834) DUF3915 PF13054.6 EAU90689.2 - 0.0067 16.4 8.8 0.21 11.6 7.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) MAP17 PF15807.5 EAU90689.2 - 0.12 12.6 2.8 0.22 11.7 0.0 2.4 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NEMP PF10225.9 EAU90689.2 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NEMP family Phage_Gp23 PF10669.9 EAU90689.2 - 5.6 7.3 6.5 1 9.7 0.7 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) INSC_LBD PF16748.5 EAU90694.2 - 0.16 11.4 0.2 18 4.9 0.1 2.4 2 0 0 2 2 2 0 Inscuteable LGN-binding domain F-box PF00646.33 EAU90694.2 - 0.21 11.5 1.2 0.99 9.4 1.2 2.2 1 1 0 1 1 1 0 F-box domain Ank_2 PF12796.7 EAU90698.2 - 2.7e-09 37.5 0.3 2.8e-08 34.2 0.0 2.8 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90698.2 - 3.6e-09 37.0 0.0 1.3e-07 32.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EAU90698.2 - 4.4e-08 33.2 3.5 0.013 15.9 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EAU90698.2 - 3.3e-07 30.4 0.2 6.2e-06 26.4 0.0 2.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90698.2 - 4.4e-06 26.6 3.4 0.44 11.3 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat NACHT PF05729.12 EAU90698.2 - 6.9e-06 26.1 0.0 5.4e-05 23.2 0.0 2.4 2 1 1 3 3 3 1 NACHT domain NB-ARC PF00931.22 EAU90698.2 - 0.032 13.4 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 EAU90698.2 - 0.033 14.5 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain IBR PF01485.21 EAU90699.2 - 2.4e-13 50.1 21.3 1.2e-09 38.2 6.2 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EAU90699.2 - 0.00025 21.0 6.2 0.00025 21.0 6.2 2.2 2 0 0 2 2 1 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 EAU90699.2 - 0.0012 18.8 5.0 0.0012 18.8 5.0 2.8 3 0 0 3 3 3 1 Zinc finger domain zf-RING_2 PF13639.6 EAU90699.2 - 0.0052 17.1 4.4 0.0052 17.1 4.4 3.7 2 1 2 4 4 3 1 Ring finger domain zf-CCCH PF00642.24 EAU90699.2 - 0.0096 15.8 8.9 0.41 10.6 2.9 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4 PF00097.25 EAU90699.2 - 0.0099 15.7 5.1 0.0099 15.7 5.1 3.6 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EAU90699.2 - 0.036 13.9 0.2 13 5.7 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EAU90699.2 - 0.063 14.0 0.1 0.063 14.0 0.1 3.7 4 0 0 4 4 4 0 Torus domain DUF5401 PF17380.2 EAU90699.2 - 0.089 10.9 35.2 0.14 10.2 35.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Presenilin PF01080.17 EAU90699.2 - 2.4 6.9 6.9 4.1 6.1 6.9 1.3 1 0 0 1 1 1 0 Presenilin zf-CCCH_4 PF18044.1 EAU90699.2 - 7.2 6.5 13.2 0.039 13.8 3.7 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger AAA_12 PF13087.6 EAU90702.2 - 1.2e-56 191.5 0.0 2.1e-56 190.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EAU90702.2 - 2e-23 83.5 0.4 2e-23 83.5 0.4 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU90702.2 - 1e-09 38.9 0.2 1.8e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EAU90702.2 - 1.2e-06 28.2 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 EAU90702.2 - 5.8e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU90702.2 - 0.0032 17.2 0.1 3.1 7.5 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EAU90702.2 - 0.13 11.7 0.2 7 6.1 0.1 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region Ank_2 PF12796.7 EAU90705.2 - 3e-47 159.1 8.1 1.1e-11 45.1 0.0 5.6 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90705.2 - 4.9e-27 94.0 7.0 2e-05 25.0 0.0 8.2 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EAU90705.2 - 9.1e-24 82.8 7.7 0.00021 21.6 0.0 9.3 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.6 EAU90705.2 - 1.1e-23 80.7 1.0 0.01 16.3 0.0 8.2 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EAU90705.2 - 2.5e-22 78.7 9.2 6e-07 29.6 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU90705.2 - 0.00037 20.8 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU90705.2 - 0.00047 20.1 0.1 0.0016 18.4 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU90705.2 - 0.0083 16.5 0.5 0.048 14.0 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.6 EAU90705.2 - 0.024 15.0 0.0 0.11 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EAU90705.2 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) QSregVF_b PF12843.7 EAU90706.2 - 0.0035 17.2 0.2 0.0064 16.4 0.2 1.4 1 0 0 1 1 1 1 Putative quorum-sensing-regulated virulence factor SET PF00856.28 EAU90707.1 - 5.8e-11 43.1 0.0 3e-10 40.7 0.0 2.1 2 1 0 2 2 2 1 SET domain Ank_2 PF12796.7 EAU90708.2 - 7.4e-40 135.4 1.1 8.5e-14 51.9 0.0 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU90708.2 - 6.2e-34 115.9 3.3 4e-07 30.4 0.0 8.1 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EAU90708.2 - 3.3e-33 112.7 1.9 6.3e-05 23.2 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EAU90708.2 - 1.7e-27 95.1 5.1 5.1e-07 29.9 0.2 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90708.2 - 9.4e-27 90.1 0.6 0.00065 20.0 0.0 8.3 7 1 0 7 7 7 5 Ankyrin repeat NapD PF03927.13 EAU90708.2 - 0.084 12.9 0.0 8.6 6.5 0.0 3.7 3 1 1 4 4 4 0 NapD protein SQS_PSY PF00494.19 EAU90709.2 - 1.4e-36 126.4 0.0 1.8e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PRIMA1 PF16101.5 EAU90713.2 - 0.021 14.9 11.7 0.032 14.3 11.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EAU90713.2 - 0.081 12.4 9.8 0.11 12.0 9.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EAU90713.2 - 6.4 6.8 14.1 4.2 7.4 12.8 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF2861 PF11060.8 EAU90716.1 - 0.079 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) Syntaxin-6_N PF09177.11 EAU90716.1 - 0.1 13.2 0.1 4 8.1 0.0 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SET PF00856.28 EAU90717.1 - 6.1e-10 39.7 0.0 9.7e-09 35.8 0.0 2.7 2 1 0 2 2 2 1 SET domain SE PF08491.10 EAU90718.1 - 2.5e-94 315.4 0.0 3.4e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EAU90718.1 - 7e-12 45.6 0.1 8.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EAU90718.1 - 8.8e-10 38.3 0.6 5.6e-09 35.7 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EAU90718.1 - 1e-06 28.1 0.5 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EAU90718.1 - 5.4e-06 25.8 0.3 2.5e-05 23.7 0.5 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU90718.1 - 0.00028 20.0 0.1 0.0031 16.6 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 EAU90718.1 - 0.0012 18.0 0.8 0.34 10.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EAU90718.1 - 0.0029 17.8 0.1 0.0066 16.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EAU90718.1 - 0.0029 16.5 0.4 2.2 7.0 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase Thi4 PF01946.17 EAU90718.1 - 0.0091 15.3 0.0 0.041 13.1 0.0 1.9 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.19 EAU90718.1 - 0.014 14.8 0.2 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 EAU90718.1 - 0.017 15.1 0.4 0.38 10.7 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EAU90718.1 - 0.022 15.3 0.1 3.2 8.4 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase dCMP_cyt_deam_1 PF00383.23 EAU90719.2 - 9.8e-19 67.1 0.0 1.2e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EAU90719.2 - 9.9e-15 54.9 0.7 3.1e-12 46.8 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EAU90719.2 - 0.0024 17.5 2.3 0.061 12.9 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases ADH_N PF08240.12 EAU90719.2 - 0.056 13.3 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Phage_holin_3_6 PF07332.11 EAU90720.2 - 0.058 13.4 5.0 0.87 9.6 0.2 2.4 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5392 PF17370.2 EAU90720.2 - 0.98 9.5 4.8 3 7.9 0.7 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5392) DnaJ PF00226.31 EAU90721.2 - 1e-08 35.2 0.1 1.8e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4366 PF14283.6 EAU90724.2 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Rootletin PF15035.6 EAU90725.2 - 0.015 15.3 0.6 0.44 10.5 0.0 2.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ArfGap PF01412.18 EAU90725.2 - 0.02 15.0 0.4 0.052 13.6 0.4 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf ABC_tran_CTD PF16326.5 EAU90725.2 - 0.69 10.2 3.4 2.4 8.5 0.2 3.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain CDC45 PF02724.14 EAU90726.1 - 5 5.3 8.2 7.4 4.7 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Tet_JBP PF12851.7 EAU90730.2 - 1.2e-24 87.3 0.0 2.3e-20 73.2 0.0 2.2 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily TPR_10 PF13374.6 EAU90732.2 - 1.2e-59 196.6 6.0 1.4e-05 24.8 0.0 15.6 15 0 0 15 15 15 11 Tetratricopeptide repeat CHAT PF12770.7 EAU90732.2 - 7.7e-29 101.0 0.0 1.4e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU90732.2 - 2.2e-17 63.1 6.0 0.064 13.6 0.0 11.7 7 3 6 13 13 13 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAU90732.2 - 2.9e-10 39.7 0.0 0.56 9.9 0.0 8.8 10 0 0 10 10 10 2 TPR repeat TPR_2 PF07719.17 EAU90732.2 - 2.9e-08 33.2 2.3 11 6.4 0.0 10.0 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90732.2 - 6.4e-06 26.0 1.2 18 5.9 0.0 8.9 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_17 PF13431.6 EAU90732.2 - 2.5e-05 24.3 2.3 29 5.3 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU90732.2 - 7.5e-05 22.5 4.0 5.1 7.3 0.0 8.2 7 1 0 7 7 7 1 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EAU90732.2 - 0.00012 22.0 3.4 4.2 7.5 0.0 7.1 7 0 0 7 7 7 1 Exonuclease VII small subunit TPR_1 PF00515.28 EAU90732.2 - 0.0055 16.5 12.6 10 6.1 0.0 9.4 11 0 0 11 11 11 1 Tetratricopeptide repeat MIT PF04212.18 EAU90732.2 - 0.01 15.9 0.4 71 3.6 0.0 5.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 EAU90732.2 - 0.49 11.3 14.2 1.5e+02 3.6 0.0 9.3 12 0 0 12 12 8 0 Tetratricopeptide repeat RCC1 PF00415.18 EAU90733.2 - 3.4e-23 82.0 1.0 7.1e-05 23.4 0.0 6.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EAU90733.2 - 3.9e-14 52.8 0.0 1.8e-05 24.9 0.0 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_4 PF13637.6 EAU90733.2 - 8.3e-11 42.2 0.2 2.5e-10 40.7 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAU90733.2 - 1.5e-09 38.3 0.0 3.2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 EAU90733.2 - 2.5e-08 33.5 9.0 4.9e-08 32.6 0.1 4.8 6 0 0 6 6 6 1 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 EAU90733.2 - 6.3e-08 32.7 0.4 0.0012 19.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU90733.2 - 1.3e-07 31.3 0.8 0.012 16.1 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAU90733.2 - 0.00012 22.4 0.9 0.15 12.5 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat EKLF_TAD1 PF16832.5 EAU90733.2 - 0.024 14.5 1.7 0.073 13.0 1.7 1.8 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 SRP-alpha_N PF04086.13 EAU90734.1 - 3.1 7.6 10.7 5.6 6.8 10.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM104 PF15434.6 EAU90734.1 - 4.4 7.9 7.1 1.8 9.2 2.0 2.2 1 1 1 2 2 2 0 Family 104 SEEEED PF14797.6 EAU90734.1 - 9.9 6.3 12.7 0.13 12.4 4.6 1.9 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex TPR_10 PF13374.6 EAU90735.2 - 3.8e-63 207.8 12.0 7.2e-07 28.9 0.1 12.3 11 0 0 11 11 11 11 Tetratricopeptide repeat CHAT PF12770.7 EAU90735.2 - 6.9e-27 94.6 0.0 1.4e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU90735.2 - 1.5e-13 50.9 14.8 0.96 9.8 0.0 11.9 9 3 4 13 13 13 4 Tetratricopeptide repeat TPR_17 PF13431.6 EAU90735.2 - 4.6e-06 26.6 1.1 4 8.0 0.1 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90735.2 - 0.00046 19.9 0.3 1.2e+02 2.7 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat MMS19_C PF12460.8 EAU90735.2 - 0.16 11.0 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal Dynamin_M PF01031.20 EAU90739.2 - 1.9e-109 365.3 0.0 5.3e-109 363.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EAU90739.2 - 1e-54 185.1 0.0 1.8e-54 184.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAU90739.2 - 1e-30 105.7 2.7 8.7e-30 102.7 1.5 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAU90739.2 - 6.7e-05 23.0 0.1 0.0003 20.9 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU90739.2 - 0.016 14.6 0.1 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AIG1 family ABC_tran PF00005.27 EAU90739.2 - 0.058 13.9 0.0 10 6.6 0.0 3.2 3 0 0 3 3 3 0 ABC transporter AAA_15 PF13175.6 EAU90739.2 - 0.13 12.0 0.2 8 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain TipAS PF07739.13 EAU90739.2 - 0.19 12.2 0.0 0.72 10.4 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain TPR_10 PF13374.6 EAU90740.1 - 1.3e-41 139.3 4.9 1.1e-05 25.2 0.1 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat CHAT PF12770.7 EAU90740.1 - 5.6e-23 81.8 0.0 1.1e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.6 EAU90740.1 - 1.1e-08 34.9 0.1 2.3 8.8 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU90740.1 - 2.1e-07 31.5 12.5 0.036 14.7 0.1 6.9 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90740.1 - 0.057 13.7 2.8 53 4.4 0.0 6.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU90740.1 - 0.18 11.5 0.0 13 5.6 0.0 4.2 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 EAU90740.1 - 3.8 7.9 11.9 2.5 8.4 0.1 6.7 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90740.1 - 7.6 7.6 12.4 61 4.8 0.0 8.2 12 0 0 12 12 12 0 Tetratricopeptide repeat BCS1_N PF08740.11 EAU90741.2 - 4.6e-46 157.2 1.2 4.6e-46 157.2 1.2 2.9 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 EAU90741.2 - 3.2e-15 56.7 0.0 1.4e-07 32.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU90741.2 - 0.00012 22.5 2.4 0.0016 18.9 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EAU90741.2 - 0.0015 18.7 0.0 0.0041 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EAU90741.2 - 0.01 15.6 0.0 0.01 15.6 0.0 2.0 2 1 0 2 2 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 EAU90741.2 - 0.013 14.9 0.0 0.46 9.8 0.0 2.6 3 0 0 3 3 3 0 KaiC RuvB_N PF05496.12 EAU90741.2 - 0.05 13.4 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EAU90741.2 - 0.067 13.1 0.1 0.29 11.0 0.1 2.1 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EAU90741.2 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region XRN_M PF17846.1 EAU90741.2 - 0.17 10.8 13.8 0.26 10.2 13.8 1.3 1 0 0 1 1 1 0 Xrn1 helical domain AAA_3 PF07726.11 EAU90741.2 - 0.18 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EAU90741.2 - 3.5 7.3 0.0 3.5 7.3 0.0 3.0 2 1 0 2 2 1 0 AAA domain RNase_H2_suC PF08615.11 EAU90742.1 - 3.2e-18 66.3 0.0 5.1e-18 65.6 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MelC1 PF06236.11 EAU90742.1 - 0.11 12.6 4.0 0.065 13.3 1.5 2.0 1 1 1 2 2 2 0 Tyrosinase co-factor MelC1 DUF2981 PF11200.8 EAU90742.1 - 0.53 10.0 5.2 0.87 9.3 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Ish1 PF10281.9 EAU90744.2 - 0.035 14.4 0.2 0.21 11.9 0.1 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein TMEM247 PF15444.6 EAU90744.2 - 0.23 11.5 5.3 0.38 10.8 5.3 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Vma12 PF11712.8 EAU90744.2 - 0.46 10.5 3.3 7.8 6.6 2.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YabA PF06156.13 EAU90744.2 - 0.78 10.4 5.1 2.8 8.6 5.1 1.9 1 0 0 1 1 1 0 Initiation control protein YabA DUF3801 PF12687.7 EAU90744.2 - 2.2 8.3 9.2 4.4 7.3 9.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF2570 PF10828.8 EAU90744.2 - 3.7 7.4 8.3 8 6.3 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Plavaka PF18759.1 EAU90745.1 - 3.1e-44 151.5 0.0 1.5e-42 146.0 0.0 2.2 1 1 0 1 1 1 1 Plavaka transposase GPI-anchored PF10342.9 EAU90746.1 - 4.4e-10 40.2 0.7 6.9e-10 39.6 0.7 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family TFIIE-A_C PF11521.8 EAU90746.1 - 1.8 8.9 8.2 3.2 8.1 8.2 1.3 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha CENP-B_dimeris PF09026.10 EAU90746.1 - 3.8 8.0 9.9 7.3 7.1 9.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ran_BP1 PF00638.18 EAU90747.2 - 0.0008 19.7 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain DUF4653 PF15546.6 EAU90748.1 - 0.082 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) F-box-like PF12937.7 EAU90749.2 - 0.0089 15.9 0.6 0.028 14.3 0.6 1.9 1 0 0 1 1 1 1 F-box-like CRISPR_Cse2 PF09485.10 EAU90750.2 - 0.00064 20.3 1.1 0.0082 16.7 0.1 2.8 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) COQ9 PF08511.11 EAU90750.2 - 0.066 13.0 1.4 0.22 11.3 1.4 1.9 1 0 0 1 1 1 0 COQ9 DUF3040 PF11239.8 EAU90750.2 - 0.11 12.8 0.5 0.59 10.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) TPR_10 PF13374.6 EAU90750.2 - 0.19 11.7 1.1 0.69 9.9 1.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SelP_N PF04592.14 EAU90750.2 - 5.7 6.3 18.4 21 4.4 18.4 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DPPIV_N PF00930.21 EAU90752.2 - 4.2e-96 321.8 0.2 5.6e-96 321.4 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EAU90752.2 - 2.2e-45 154.7 0.6 4.1e-45 153.9 0.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EAU90752.2 - 3.1e-07 30.3 1.6 7.8e-07 28.9 1.1 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EAU90752.2 - 0.0001 22.0 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU90752.2 - 0.0027 18.3 3.3 0.0058 17.3 0.0 2.9 3 1 0 3 3 3 1 Alpha/beta hydrolase family COesterase PF00135.28 EAU90752.2 - 0.0074 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 EAU90752.2 - 0.018 14.3 0.1 0.11 11.7 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 EAU90752.2 - 0.022 14.3 0.2 0.24 10.9 0.2 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.14 EAU90752.2 - 0.054 12.8 0.2 0.13 11.6 0.2 1.6 1 0 0 1 1 1 0 Secretory lipase PD40 PF07676.12 EAU90752.2 - 0.064 13.2 0.9 4.4 7.4 0.2 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AXE1 PF05448.12 EAU90752.2 - 0.07 11.8 0.0 0.52 8.9 0.0 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) CSD2 PF17876.1 EAU90752.2 - 0.085 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Cold shock domain Abhydrolase_2 PF02230.16 EAU90752.2 - 0.1 12.4 0.0 2.8 7.7 0.0 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase SYS1 PF09801.9 EAU90753.1 - 2e-23 83.1 3.4 3.7e-16 59.6 2.3 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DUF3303 PF11746.8 EAU90754.2 - 0.027 14.7 0.0 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3303) CBP_BcsQ PF06564.12 EAU90754.2 - 0.12 11.9 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ TPR_10 PF13374.6 EAU90758.2 - 1.9e-47 157.9 0.1 4.3e-05 23.2 0.0 11.2 10 1 1 11 11 11 10 Tetratricopeptide repeat CHAT PF12770.7 EAU90758.2 - 2.6e-27 96.0 0.0 5.2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU90758.2 - 1.8e-13 50.6 0.1 0.32 11.3 0.0 9.5 7 2 1 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90758.2 - 0.0064 16.3 0.6 28 4.7 0.1 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EAU90758.2 - 0.014 15.4 2.9 1.4e+02 2.7 0.1 6.7 7 0 0 7 7 7 0 Exonuclease VII small subunit DUF4404 PF14357.6 EAU90758.2 - 0.019 15.6 2.3 17 6.2 0.0 5.1 5 1 1 6 6 6 0 Domain of unknown function (DUF4404) DUF4164 PF13747.6 EAU90758.2 - 6.2 7.2 9.7 91 3.4 0.0 5.8 6 0 0 6 6 6 0 Domain of unknown function (DUF4164) TPR_10 PF13374.6 EAU90759.2 - 4.4e-48 159.9 13.6 2.3e-05 24.1 0.0 10.9 10 0 0 10 10 10 10 Tetratricopeptide repeat CHAT PF12770.7 EAU90759.2 - 4.9e-27 95.1 0.0 9.9e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU90759.2 - 2.4e-07 30.9 11.1 3.2 8.1 0.0 9.2 7 2 4 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAU90759.2 - 0.0095 16.0 7.8 8.1 6.8 0.0 7.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90759.2 - 0.02 15.1 0.2 63 4.2 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EAU90759.2 - 0.1 13.2 10.4 0.53 11.0 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90759.2 - 0.11 13.4 21.3 52 5.0 0.1 10.1 8 1 3 11 11 11 0 Tetratricopeptide repeat ARA70 PF12489.8 EAU90759.2 - 0.16 12.2 0.0 1 9.5 0.0 2.4 3 0 0 3 3 3 0 Nuclear coactivator TPR_10 PF13374.6 EAU90760.2 - 9.7e-105 340.0 13.2 1.1e-07 31.5 0.0 17.5 17 0 0 17 17 17 16 Tetratricopeptide repeat TPR_12 PF13424.6 EAU90760.2 - 2.1e-29 101.6 4.2 0.066 13.5 0.1 16.6 10 7 6 17 17 17 5 Tetratricopeptide repeat CHAT PF12770.7 EAU90760.2 - 2.4e-27 96.1 0.0 5.4e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.6 EAU90760.2 - 8.9e-16 57.1 3.8 23 5.6 0.0 13.4 13 0 0 13 13 13 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU90760.2 - 7.1e-08 32.0 9.4 20 5.6 0.0 12.6 17 0 0 17 17 17 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU90760.2 - 4.3e-05 23.4 0.3 64 4.1 0.0 8.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU90760.2 - 4.6e-05 23.9 16.9 61 4.8 0.1 13.5 16 1 1 17 17 14 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU90760.2 - 0.00017 21.2 0.0 0.79 9.5 0.0 6.8 8 0 0 8 8 8 1 TPR repeat RFamide_26RFa PF11109.8 EAU90760.2 - 0.0003 21.3 0.3 1.9 9.0 0.0 6.0 7 3 1 8 8 8 1 Orexigenic neuropeptide Qrfp/P518 TPR_1 PF00515.28 EAU90760.2 - 0.00049 19.8 10.3 58 3.7 0.0 11.1 14 0 0 14 14 14 0 Tetratricopeptide repeat DUF4404 PF14357.6 EAU90760.2 - 0.0009 19.8 23.5 0.61 10.8 0.0 8.5 9 0 0 9 9 8 2 Domain of unknown function (DUF4404) MIT PF04212.18 EAU90760.2 - 0.047 13.8 0.2 1.1e+02 2.9 0.0 5.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain DUF4326 PF14216.6 EAU90760.2 - 0.15 12.8 0.0 4.9e+02 1.5 0.0 5.5 6 2 1 7 7 6 0 Domain of unknown function (DUF4326) DeoC PF01791.9 EAU90761.2 - 1e-13 51.4 0.5 1.3e-13 51.1 0.5 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 EAU90761.2 - 0.11 12.0 0.4 1.1 8.7 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein zf-HC5HC2H_2 PF13832.6 EAU90763.2 - 2.5e-32 111.3 4.6 2.5e-32 111.3 4.6 2.7 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EAU90763.2 - 3.7e-24 84.8 2.0 3.7e-24 84.8 2.0 3.5 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.9 EAU90763.2 - 1.7e-22 80.5 2.1 1.7e-22 80.5 2.1 3.1 3 0 0 3 3 3 1 Enhancer of polycomb-like Bromodomain PF00439.25 EAU90763.2 - 5.9e-19 67.9 0.3 1.3e-18 66.8 0.3 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 EAU90763.2 - 3.4e-15 55.3 2.6 3.4e-15 55.3 2.6 3.0 3 0 0 3 3 3 2 PHD-finger PWWP PF00855.17 EAU90763.2 - 9.5e-13 48.4 1.1 3.9e-12 46.4 1.1 2.1 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 EAU90763.2 - 1.1e-10 41.2 22.8 2.1e-10 40.3 5.7 3.7 4 0 0 4 4 4 2 PHD-finger C1_1 PF00130.22 EAU90763.2 - 0.011 15.5 0.4 0.011 15.5 0.4 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EAU90763.2 - 0.53 10.6 16.4 0.33 11.3 2.1 2.8 3 0 0 3 3 3 0 C1 domain Pkinase_fungal PF17667.1 EAU90764.1 - 1.6e-78 264.3 0.0 6.8e-31 107.4 0.0 3.4 2 1 1 3 3 3 3 Fungal protein kinase APH PF01636.23 EAU90764.1 - 3.1e-05 24.0 3.1 0.83 9.5 0.0 3.5 2 2 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 EAU90764.1 - 0.0024 17.5 0.0 0.6 9.7 0.0 3.0 3 0 0 3 3 3 2 RIO1 family Pkinase PF00069.25 EAU90764.1 - 0.19 11.1 0.0 0.5 9.7 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain Histone PF00125.24 EAU90765.2 - 9.9e-28 97.1 1.0 1.4e-27 96.6 0.3 1.7 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EAU90765.2 - 0.00064 19.8 0.3 0.0021 18.2 0.0 1.9 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EAU90765.2 - 0.0015 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EAU90765.2 - 0.0058 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein Mis12 PF05859.12 EAU90766.1 - 7.8e-45 152.2 0.1 1.2e-44 151.6 0.1 1.3 1 0 0 1 1 1 1 Mis12 protein Lzipper-MIP1 PF14389.6 EAU90766.1 - 0.0081 16.4 4.1 0.0081 16.4 4.1 1.8 2 1 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Spc29 PF17082.5 EAU90766.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 2 0 0 2 2 2 0 Spindle Pole Component 29 FliT PF05400.13 EAU90766.1 - 0.23 12.3 7.9 0.55 11.1 7.9 1.5 1 0 0 1 1 1 0 Flagellar protein FliT p450 PF00067.22 EAU90768.2 - 1.8e-44 152.3 0.1 2.4e-44 151.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EAU90769.1 - 0.00015 21.6 0.5 0.0003 20.6 0.5 1.5 1 0 0 1 1 1 1 F-box-like FMN_red PF03358.15 EAU90770.1 - 7.3e-10 38.8 0.0 1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EAU90770.1 - 0.002 18.4 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 EAU90770.1 - 0.0082 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF1899 PF08953.11 EAU90771.1 - 4.5e-26 90.5 0.2 1.1e-25 89.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EAU90771.1 - 5.4e-19 67.8 0.3 1.2e-18 66.7 0.3 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EAU90771.1 - 2.4e-17 63.0 4.2 1.8e-05 25.4 0.0 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU90771.1 - 3.8e-06 27.1 0.0 0.074 13.4 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU90771.1 - 0.26 10.2 0.0 3.6 6.5 0.0 2.4 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GCV_T PF01571.21 EAU90772.1 - 6.4e-84 281.3 0.0 7.7e-84 281.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EAU90772.1 - 3.5e-21 74.9 0.1 7.9e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EAU90772.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 1 0 1 1 1 0 Sarcosine oxidase, gamma subunit family TPR_10 PF13374.6 EAU90774.2 - 6.8e-36 121.2 7.8 7.5e-08 32.0 0.1 10.5 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 EAU90774.2 - 1.1e-13 51.3 4.8 0.35 11.2 0.0 10.1 9 2 3 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 EAU90774.2 - 0.0013 18.4 4.0 9.2 6.3 0.0 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU90774.2 - 0.014 15.7 4.5 83 3.9 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ActA PF05058.12 EAU90774.2 - 0.054 11.8 0.2 15 3.7 0.0 3.0 3 0 0 3 3 3 0 ActA Protein Zn_clus PF00172.18 EAU90780.2 - 4e-08 33.2 13.6 8.3e-08 32.2 13.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_3 PF07969.11 EAU90782.2 - 6.7e-57 194.0 0.0 4.1e-39 135.3 0.0 2.1 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EAU90782.2 - 1.1e-08 34.7 0.0 2.9e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family HTH_OrfB_IS605 PF12323.8 EAU90783.1 - 0.041 13.4 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Viral_Beta_CD PF04530.12 EAU90783.1 - 0.067 13.5 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Viral Beta C/D like family Cu-oxidase PF00394.22 EAU90786.2 - 2.1e-46 158.0 0.0 4.2e-42 144.0 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU90786.2 - 6.5e-34 116.5 0.3 5.5e-33 113.5 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU90786.2 - 6.2e-33 113.4 5.3 2.6e-32 111.4 0.1 3.0 2 1 0 2 2 2 1 Multicopper oxidase HSP70 PF00012.20 EAU90789.1 - 7.4e-156 519.8 17.3 4.6e-148 494.1 0.2 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EAU90789.1 - 2.4e-10 39.7 0.5 7.4e-10 38.1 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein DUF1149 PF06619.11 EAU90789.1 - 0.071 13.4 0.7 0.53 10.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) HsbA PF12296.8 EAU90789.1 - 0.076 13.4 2.4 0.19 12.2 0.2 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A BTB PF00651.31 EAU90790.2 - 0.00028 21.1 0.0 0.00062 20.0 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Cu_amine_oxidN1 PF07833.11 EAU90790.2 - 0.075 13.5 0.0 1.8 9.1 0.0 2.4 1 1 1 2 2 2 0 Copper amine oxidase N-terminal domain BTB PF00651.31 EAU90792.2 - 0.00014 22.0 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Defensin_beta_2 PF13841.6 EAU90792.2 - 0.43 11.1 2.6 1.1 9.8 2.6 1.7 1 0 0 1 1 1 0 Beta defensin OrsD PF12013.8 EAU90794.1 - 0.51 10.8 6.7 0.55 10.7 5.4 1.7 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 EAU90794.1 - 1.7 9.7 10.0 1.2 10.2 1.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Trypan_PARP PF05887.11 EAU90794.1 - 2.9 7.9 38.8 0.066 13.2 5.3 3.4 3 1 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) E7 PF00527.18 EAU90794.1 - 3.7 7.8 5.4 0.73 10.1 0.9 2.0 2 0 0 2 2 2 0 E7 protein, Early protein MFS_1 PF07690.16 EAU90796.2 - 2.5e-24 85.9 41.3 3.9e-24 85.2 37.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3754 PF12576.8 EAU90796.2 - 0.17 11.8 0.6 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) UL41A PF17591.2 EAU90796.2 - 3.6 7.8 5.5 2.3 8.4 0.0 3.1 3 0 0 3 3 3 0 Herpesvirus UL41A G-alpha PF00503.20 EAU90798.2 - 2.1e-90 303.4 0.1 2.5e-90 303.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU90798.2 - 8.4e-14 51.4 1.1 4.3e-09 36.1 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAU90798.2 - 0.0012 18.3 1.9 0.088 12.1 0.0 2.8 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EAU90798.2 - 0.016 15.4 0.3 5.6 7.2 0.1 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EAU90798.2 - 0.051 13.3 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EAU90798.2 - 0.089 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EAU90798.2 - 0.091 12.9 0.1 2.8 8.0 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PMP1_2 PF08114.11 EAU90802.2 - 0.12 12.2 0.7 2.6 7.9 0.0 2.7 3 0 0 3 3 3 0 ATPase proteolipid family Beta-lactamase PF00144.24 EAU90805.1 - 2e-21 76.6 0.8 5.8e-21 75.1 0.8 1.7 1 0 0 1 1 1 1 Beta-lactamase DEAD PF00270.29 EAU90806.1 - 0.00019 21.2 0.0 0.00029 20.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3810 PF12725.7 EAU90809.2 - 8.2 5.7 7.3 0.45 9.8 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) FtsX PF02687.21 EAU90809.2 - 9.3 6.8 16.9 8.2 7.0 0.5 3.3 2 1 1 3 3 3 0 FtsX-like permease family FMO-like PF00743.19 EAU90810.2 - 1.1e-17 63.7 0.1 8.8e-13 47.5 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAU90810.2 - 4.3e-15 55.7 0.1 1.1e-12 47.8 0.2 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU90810.2 - 1.9e-14 53.6 0.0 7e-06 25.5 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAU90810.2 - 1.6e-09 37.4 0.2 1.6e-05 24.2 0.1 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EAU90810.2 - 1.6e-07 31.7 0.2 0.001 19.6 0.1 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU90810.2 - 0.00012 22.3 0.0 0.00074 19.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EAU90810.2 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EAU90810.2 - 0.016 14.6 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EAU90810.2 - 0.029 13.1 0.0 0.094 11.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EAU90810.2 - 0.029 13.4 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EAU90810.2 - 0.11 11.6 0.0 0.38 9.8 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EAU90810.2 - 0.15 11.2 0.1 0.29 10.2 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EAU90810.2 - 0.23 11.5 0.2 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 EAU90811.1 - 6.1e-19 67.8 0.0 4.6e-13 48.4 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EAU90811.1 - 1.6e-17 63.8 0.2 2.8e-13 49.8 0.5 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EAU90811.1 - 3.5e-15 56.0 0.0 1.7e-06 27.5 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EAU90811.1 - 2.1e-11 43.6 0.3 1.9e-06 27.3 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EAU90811.1 - 5.8e-07 30.0 0.2 0.0011 19.5 0.1 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU90811.1 - 0.00014 22.0 0.0 0.00076 19.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EAU90811.1 - 0.0013 18.0 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EAU90811.1 - 0.027 13.9 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EAU90811.1 - 0.027 13.2 0.0 0.097 11.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EAU90811.1 - 0.06 12.4 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EAU90811.1 - 0.1 11.6 0.0 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EAU90811.1 - 0.11 11.5 0.1 0.3 10.1 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EAU90811.1 - 0.24 11.4 0.7 27 4.7 0.2 3.5 3 1 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_4 PF01565.23 EAU90814.2 - 1.9e-28 98.9 3.6 2.9e-28 98.3 3.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU90814.2 - 4.7e-10 39.4 0.1 9.2e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EAU90815.1 - 1.6e-31 108.9 3.1 2.6e-31 108.2 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EAU90815.1 - 7.9e-16 57.9 1.0 1.4e-15 57.1 1.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like H_lectin PF09458.10 EAU90816.2 - 1.4e-37 127.7 3.6 4.2e-16 58.9 0.1 4.3 4 0 0 4 4 4 4 H-type lectin domain zf-MYND PF01753.18 EAU90818.2 - 2.9e-08 33.7 10.6 5.9e-08 32.7 10.6 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EAU90818.2 - 0.9 9.7 7.4 2.5 8.2 7.4 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Lipase_GDSL_2 PF13472.6 EAU90819.1 - 9.4e-23 81.5 1.2 1.5e-22 80.8 1.2 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU90819.1 - 2.4e-07 30.9 0.0 3.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-MYND PF01753.18 EAU90821.1 - 1.1e-07 31.8 6.9 2.2e-07 30.8 6.9 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 EAU90822.2 - 1.7e-08 34.4 9.0 3.6e-08 33.4 9.0 1.6 1 0 0 1 1 1 1 MYND finger Tmemb_170 PF10190.9 EAU90822.2 - 0.29 11.5 6.5 0.99 9.8 6.5 1.9 1 0 0 1 1 1 0 Putative transmembrane protein 170 YGGT PF02325.17 EAU90822.2 - 5.5 7.5 10.9 0.36 11.3 1.9 3.2 3 0 0 3 3 3 0 YGGT family zf-MYND PF01753.18 EAU90823.2 - 6.6e-11 42.1 5.2 1.2e-10 41.3 5.2 1.4 1 0 0 1 1 1 1 MYND finger PWWP PF00855.17 EAU90824.1 - 8.5e-20 71.0 0.0 8.5e-20 71.0 0.0 2.6 3 0 0 3 3 3 1 PWWP domain Med26 PF08711.11 EAU90824.1 - 0.00036 20.5 1.8 0.00092 19.2 0.0 2.5 3 0 0 3 3 3 1 TFIIS helical bundle-like domain FLYWCH PF04500.16 EAU90825.2 - 0.16 12.1 2.7 2.8 8.1 0.2 2.3 2 0 0 2 2 2 0 FLYWCH zinc finger domain DUF1387 PF07139.11 EAU90833.1 - 0.058 13.1 4.7 0.27 10.9 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 EAU90833.1 - 9 6.0 9.0 7.4 6.3 7.9 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF202 PF02656.15 EAU90834.2 - 1.7e-15 57.2 4.1 1.7e-15 57.2 4.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3188 PF11384.8 EAU90834.2 - 0.099 12.4 0.4 0.099 12.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) INT_SG_DDX_CT_C PF15300.6 EAU90837.2 - 0.018 14.8 0.2 0.032 14.0 0.2 1.4 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Phage_integrase PF00589.22 EAU90846.1 - 9.5e-05 22.3 0.1 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 Phage integrase family F-box PF00646.33 EAU90847.2 - 0.055 13.4 0.2 0.21 11.5 0.2 2.0 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EAU90849.2 - 0.0037 17.1 0.3 0.0087 15.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90849.2 - 0.048 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain GATase_5 PF13507.6 EAU90850.2 - 9.4e-102 339.5 0.0 2.7e-101 338.1 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EAU90850.2 - 5.4e-42 143.6 2.6 9e-29 100.6 0.4 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EAU90850.2 - 3.5e-31 107.6 0.0 8.6e-31 106.3 0.0 1.7 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EAU90850.2 - 4.4e-21 75.2 0.0 9e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EAU90850.2 - 0.1 13.3 0.3 1.8 9.2 0.0 2.9 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain ETX_MTX2 PF03318.13 EAU90851.2 - 2.1e-08 34.2 6.7 3.4e-08 33.5 6.4 1.5 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 EAU90851.2 - 2.5e-07 30.2 0.5 5.8e-06 25.8 1.1 2.0 2 0 0 2 2 2 1 Aerolysin toxin F-box-like PF12937.7 EAU90852.1 - 0.00011 22.0 0.1 0.0003 20.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like Use1 PF09753.9 EAU90853.1 - 2.1e-14 53.9 3.4 3.8e-14 53.0 0.1 2.4 2 1 0 2 2 2 1 Membrane fusion protein Use1 SNARE PF05739.19 EAU90853.1 - 0.057 13.4 0.2 0.057 13.4 0.2 2.1 2 0 0 2 2 2 0 SNARE domain zf-DBF PF07535.12 EAU90854.1 - 0.0037 17.3 0.2 0.0075 16.4 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2_4 PF13894.6 EAU90854.1 - 0.34 11.9 5.6 12 7.0 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU90854.1 - 1.1 9.8 5.8 0.73 10.4 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type F-box-like PF12937.7 EAU90855.2 - 0.054 13.4 0.7 0.054 13.4 0.7 3.0 3 0 0 3 3 3 0 F-box-like Rnk_N PF14760.6 EAU90856.2 - 0.12 12.9 0.5 31 5.2 0.0 2.9 1 1 1 2 2 2 0 Rnk N-terminus BUD22 PF09073.10 EAU90857.2 - 0.035 13.4 12.6 0.044 13.1 12.6 1.1 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 EAU90857.2 - 0.45 10.4 6.8 0.48 10.3 6.8 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EAU90857.2 - 0.99 8.2 7.4 1.1 8.0 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.11 EAU90857.2 - 4.3 5.5 9.9 4.3 5.5 9.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BTB PF00651.31 EAU90858.2 - 0.00026 21.2 0.0 0.00045 20.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Baculo_DNA_bind PF04786.12 EAU90858.2 - 0.03 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 ssDNA binding protein Lipase_GDSL_2 PF13472.6 EAU90859.1 - 7.9e-20 72.0 0.5 1e-19 71.6 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU90859.1 - 1.5e-09 38.2 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nucleoporin_FG PF13634.6 EAU90860.2 - 0.02 15.7 23.4 0.086 13.7 23.4 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region bZIP_2 PF07716.15 EAU90862.2 - 4.7e-09 36.2 19.3 5.1e-08 32.9 11.4 2.5 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EAU90862.2 - 1.3e-08 34.8 14.9 2e-08 34.2 9.1 2.7 3 0 0 3 3 3 1 bZIP transcription factor Nnf1 PF03980.14 EAU90862.2 - 0.0082 16.5 7.2 0.12 12.8 0.0 2.8 3 0 0 3 3 3 2 Nnf1 TSC22 PF01166.18 EAU90862.2 - 0.17 12.2 0.7 3.1 8.2 0.0 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 EAU90862.2 - 0.23 12.0 12.3 0.078 13.5 7.9 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor HAP1_N PF04849.13 EAU90862.2 - 8.2 5.5 7.7 0.54 9.4 2.3 1.7 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Arrestin_C PF02752.22 EAU90866.2 - 6.7e-10 39.5 0.2 9.5e-09 35.8 0.2 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EAU90866.2 - 2.7e-09 37.3 0.0 9.1e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EAU90866.2 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like FA_desaturase PF00487.24 EAU90868.1 - 4.7 7.0 9.7 1.3 8.8 0.0 2.8 2 1 1 3 3 3 0 Fatty acid desaturase Peptidase_M43 PF05572.13 EAU90870.1 - 9.1e-18 64.6 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU90870.1 - 9e-05 22.7 0.3 9e-05 22.7 0.3 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 EAU90870.1 - 0.0054 16.4 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_3 PF13582.6 EAU90870.1 - 0.0097 16.4 0.1 0.017 15.6 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EAU90870.1 - 0.01 15.7 0.2 0.024 14.6 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EAU90870.1 - 0.035 13.0 0.8 0.057 12.4 0.8 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 EAU90870.1 - 0.099 12.5 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin HIT PF01230.23 EAU90870.1 - 0.19 12.5 0.0 0.32 11.7 0.0 1.3 1 0 0 1 1 1 0 HIT domain PRIMA1 PF16101.5 EAU90871.2 - 0.53 10.3 2.8 14 5.7 0.0 2.2 1 1 1 2 2 2 0 Proline-rich membrane anchor 1 Abhydrolase_6 PF12697.7 EAU90872.2 - 1.9e-08 35.2 0.2 3.3e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family peroxidase PF00141.23 EAU90873.1 - 9.3e-48 162.9 0.0 1.4e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase NACHT PF05729.12 EAU90874.1 - 5.2e-09 36.2 1.1 4.4e-08 33.2 1.1 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU90874.1 - 0.0042 17.5 0.4 0.014 15.8 0.4 1.8 1 1 0 1 1 1 1 AAA ATPase domain EcKinase PF02958.20 EAU90877.2 - 0.0018 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DivIC PF04977.15 EAU90877.2 - 0.015 15.1 0.8 0.55 10.0 0.1 2.2 1 1 1 2 2 2 0 Septum formation initiator AviRa PF11599.8 EAU90877.2 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa ZapB PF06005.12 EAU90877.2 - 0.18 12.3 0.1 0.32 11.5 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB EcKinase PF02958.20 EAU90878.2 - 0.0015 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DivIC PF04977.15 EAU90878.2 - 0.011 15.4 0.8 0.48 10.2 0.1 2.2 1 1 1 2 2 2 0 Septum formation initiator AviRa PF11599.8 EAU90878.2 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa ZapB PF06005.12 EAU90878.2 - 0.15 12.5 0.1 0.27 11.7 0.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB CENP-M PF11111.8 EAU90881.2 - 0.17 11.1 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Centromere protein M (CENP-M) zf-CCHC PF00098.23 EAU90882.1 - 1.5e-09 37.5 26.4 0.00064 19.7 1.2 4.4 4 0 0 4 4 4 4 Zinc knuckle FXR_C1 PF16096.5 EAU90882.1 - 0.041 14.1 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 zf-CCHC_4 PF14392.6 EAU90882.1 - 0.077 12.7 22.4 0.1 12.3 0.3 4.2 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_2 PF13696.6 EAU90882.1 - 0.24 11.3 24.1 0.31 10.9 0.4 4.2 4 0 0 4 4 4 0 Zinc knuckle CDC45 PF02724.14 EAU90882.1 - 4.3 5.5 9.8 6.8 4.9 9.8 1.3 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EAU90882.1 - 4.9 5.8 9.9 7.3 5.3 9.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Proteasome PF00227.26 EAU90883.2 - 6.4e-54 182.3 0.1 1.1e-53 181.5 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAU90883.2 - 1.7e-13 50.0 0.1 2.9e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sialidase PF02973.16 EAU90884.1 - 0.027 14.0 0.4 0.051 13.1 0.4 1.4 1 0 0 1 1 1 0 Sialidase, N-terminal domain DPBB_1 PF03330.18 EAU90886.1 - 0.00042 20.6 0.0 0.00076 19.7 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase SKI PF01202.22 EAU90887.1 - 5.1e-09 36.4 0.0 2.5e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.6 EAU90887.1 - 2.4e-07 31.3 0.0 1.6e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAU90887.1 - 8.4e-07 29.2 0.0 1.5e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU90887.1 - 0.0012 19.3 0.0 0.002 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 EAU90887.1 - 0.002 18.0 0.0 0.39 10.5 0.0 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase ABC_tran PF00005.27 EAU90887.1 - 0.0064 17.0 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Cytidylate_kin PF02224.18 EAU90887.1 - 0.0074 16.0 0.0 0.0098 15.6 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase DUF2075 PF09848.9 EAU90887.1 - 0.0076 15.5 0.0 0.0096 15.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EAU90887.1 - 0.008 16.5 0.2 0.051 13.8 0.2 2.0 1 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAU90887.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 EAU90887.1 - 0.026 15.0 0.0 0.78 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EAU90887.1 - 0.034 14.0 0.0 0.06 13.2 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.6 EAU90887.1 - 0.034 14.4 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAU90887.1 - 0.099 13.1 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Big_1 PF02369.16 EAU90887.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) AAA_24 PF13479.6 EAU90887.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU90887.1 - 0.14 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Fungal_trans PF04082.18 EAU90888.1 - 1.4e-21 76.7 0.0 2.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU90888.1 - 0.0026 17.9 1.3 0.0026 17.9 1.3 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EAU90888.1 - 0.0097 16.0 0.1 0.028 14.6 0.1 1.8 1 0 0 1 1 1 1 Gal4-like dimerisation domain AAA_lid_2 PF17863.1 EAU90889.2 - 0.064 13.1 0.6 0.2 11.5 0.6 1.8 1 0 0 1 1 1 0 AAA lid domain Vps53_N PF04100.12 EAU90891.1 - 7.5e-97 324.7 8.0 1.4e-96 323.8 8.0 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 EAU90891.1 - 6.8e-08 32.1 7.0 6.8e-08 32.1 7.0 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 EAU90891.1 - 3.7e-05 23.7 0.1 3.7e-05 23.7 0.1 4.1 4 1 0 4 4 4 1 Vacuolar protein sorting-associated protein 53 C-terminus Sec5 PF15469.6 EAU90891.1 - 0.00092 19.1 5.5 0.00092 19.1 5.5 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 Zw10 PF06248.13 EAU90891.1 - 0.0032 16.1 7.1 0.0067 15.0 7.1 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 RecG_N PF17190.4 EAU90891.1 - 0.029 15.1 1.7 0.029 15.1 1.7 2.6 2 1 1 3 3 3 0 RecG N-terminal helical domain CorA PF01544.18 EAU90891.1 - 0.1 11.9 2.9 0.22 10.8 2.9 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1664 PF07889.12 EAU90891.1 - 0.12 12.4 9.5 0.039 14.0 4.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4795 PF16043.5 EAU90891.1 - 0.22 11.1 7.1 0.69 9.5 7.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) EST1_DNA_bind PF10373.9 EAU90891.1 - 0.79 9.1 4.0 0.57 9.6 1.1 2.1 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain Terminase_2 PF03592.16 EAU90891.1 - 3 8.3 6.7 2.2 8.7 3.9 2.2 2 0 0 2 2 2 0 Terminase small subunit FlxA PF14282.6 EAU90891.1 - 5.4 7.1 10.5 37 4.4 6.3 2.9 2 1 0 2 2 2 0 FlxA-like protein Yippee-Mis18 PF03226.14 EAU90892.1 - 6.3e-15 55.3 0.0 8.6e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ctr PF04145.15 EAU90893.2 - 4.8e-32 111.6 0.2 5.8e-32 111.4 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family HSP70 PF00012.20 EAU90894.2 - 0.14 10.3 0.0 1.1 7.4 0.0 2.0 2 0 0 2 2 2 0 Hsp70 protein IL31 PF15209.6 EAU90897.1 - 0.00064 19.5 0.4 0.002 17.9 0.4 1.8 1 0 0 1 1 1 1 Interleukin 31 MAD PF05557.13 EAU90897.1 - 0.084 11.2 24.4 0.12 10.7 5.8 3.3 2 2 2 4 4 4 0 Mitotic checkpoint protein DUF1664 PF07889.12 EAU90897.1 - 0.088 12.9 9.1 2.3 8.3 0.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 EAU90897.1 - 0.091 12.2 16.8 1.4 8.3 12.3 3.2 2 1 0 2 2 2 0 Golgin subfamily A member 5 Noelin-1 PF12308.8 EAU90897.1 - 0.093 12.7 1.0 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Neurogenesis glycoprotein DUF2408 PF10303.9 EAU90897.1 - 0.51 10.9 12.0 2.3 8.8 4.0 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF2408) Cep57_MT_bd PF06657.13 EAU90897.1 - 0.63 10.5 11.2 24 5.5 0.0 4.7 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Med9 PF07544.13 EAU90897.1 - 1.2 9.2 9.8 3.5 7.8 2.6 3.2 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 EAU90897.1 - 1.5 9.5 9.0 13 6.4 0.1 4.5 3 1 1 4 4 4 0 SlyX PI3K_P85_iSH2 PF16454.5 EAU90897.1 - 1.9 8.0 11.3 0.11 12.1 2.6 3.3 3 1 1 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APG6_N PF17675.1 EAU90897.1 - 3.1 8.3 24.4 0.25 11.9 5.9 4.1 3 2 1 4 4 4 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 EAU90897.1 - 4 7.8 11.5 7.3 7.0 2.6 4.1 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SOGA PF11365.8 EAU90897.1 - 4.5 8.5 15.4 0.35 12.0 1.9 4.5 4 1 0 5 5 5 0 Protein SOGA COG5 PF10392.9 EAU90897.1 - 8.5 6.6 16.2 0.32 11.2 2.4 3.6 3 1 0 4 4 4 0 Golgi transport complex subunit 5 Peptidase_S8 PF00082.22 EAU90898.2 - 4.7e-46 157.4 0.3 7e-46 156.8 0.3 1.1 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EAU90898.2 - 2.4e-14 54.0 0.0 4.8e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain Peptidase_S8 PF00082.22 EAU90899.2 - 1.2e-51 175.8 0.3 2.2e-51 174.9 0.3 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EAU90899.2 - 4.7e-14 53.1 0.1 1.4e-13 51.5 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain DUF916 PF06030.12 EAU90899.2 - 0.05 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) NPCBM_assoc PF10633.9 EAU90899.2 - 0.071 13.4 0.4 0.6 10.4 0.2 2.6 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.8 EAU90899.2 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Kelch_4 PF13418.6 EAU90900.2 - 9.2e-30 102.4 3.3 1.3e-07 31.5 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EAU90900.2 - 1.8e-26 91.6 2.5 3.6e-07 30.0 0.0 6.5 7 0 0 7 7 7 5 Kelch motif Muskelin_N PF06588.11 EAU90900.2 - 3.3e-26 92.4 0.0 5.3e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_6 PF13964.6 EAU90900.2 - 8.3e-23 79.9 0.9 0.00029 21.0 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EAU90900.2 - 6.3e-21 74.2 10.1 1.2e-06 28.6 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EAU90900.2 - 1.2e-17 63.1 5.1 4.2e-06 26.2 0.1 5.1 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EAU90900.2 - 5.6e-09 35.6 0.7 0.00015 21.6 0.2 4.2 3 0 0 3 3 3 2 Kelch motif 7tm_1 PF00001.21 EAU90901.2 - 1.2e-05 24.8 4.1 1.6e-05 24.3 4.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EAU90901.2 - 0.0018 18.1 10.0 0.0054 16.5 10.0 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EAU90901.2 - 0.031 14.4 0.2 0.031 14.4 0.2 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term CHZ PF09649.10 EAU90904.1 - 1.9e-13 49.6 0.2 1.9e-13 49.6 0.2 2.9 3 0 0 3 3 1 1 Histone chaperone domain CHZ LPD15 PF18828.1 EAU90904.1 - 0.027 14.3 0.5 0.045 13.6 0.5 1.4 1 1 0 1 1 1 0 Large polyvalent-protein-associated domain 15 DUF4746 PF15928.5 EAU90904.1 - 0.11 12.0 6.3 0.12 11.8 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 EAU90904.1 - 0.11 10.6 25.4 0.12 10.5 25.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 EAU90904.1 - 0.12 11.4 16.8 0.15 11.1 16.8 1.1 1 0 0 1 1 1 0 Pes-10 Trypan_PARP PF05887.11 EAU90904.1 - 0.29 11.1 9.4 0.48 10.4 9.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GP67 PF17634.2 EAU90904.1 - 0.3 11.5 22.7 0.79 10.2 18.4 2.1 2 0 0 2 2 2 0 Gene product 67 FancD2 PF14631.6 EAU90904.1 - 2.3 5.5 5.0 2.8 5.2 5.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease BUD22 PF09073.10 EAU90904.1 - 3 7.1 19.6 3.3 7.0 19.6 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EAU90904.1 - 5.5 5.2 11.8 5 5.3 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EAU90904.1 - 5.8 5.0 17.8 5.8 5.0 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 EAU90904.1 - 7.3 4.2 5.6 8 4.1 5.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 EAU90904.1 - 7.8 6.2 15.1 1.8 8.2 11.5 1.8 1 1 1 2 2 2 0 FAM176 family DUF4820 PF16091.5 EAU90904.1 - 9.1 5.6 8.5 13 5.0 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) OAD_gamma PF04277.13 EAU90905.1 - 0.00047 20.7 0.1 0.45 11.1 0.0 2.3 2 0 0 2 2 2 2 Oxaloacetate decarboxylase, gamma chain Orf78 PF06024.12 EAU90905.1 - 0.021 15.1 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) TMEM132D_C PF15706.5 EAU90905.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4834 PF16118.5 EAU90905.1 - 0.15 13.0 0.0 0.87 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PRIMA1 PF16101.5 EAU90905.1 - 0.27 11.3 3.8 9 6.4 0.1 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Rpr2 PF04032.16 EAU90906.1 - 2.7e-19 69.2 1.7 4.9e-19 68.4 1.7 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_ribbon_SprT PF17283.2 EAU90906.1 - 0.083 12.8 2.4 2.3 8.2 0.4 2.6 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Caskin-tail PF16632.5 EAU90906.1 - 0.12 12.8 0.8 0.47 10.9 0.6 2.1 1 1 1 2 2 2 0 C-terminal region of Caskin F-box-like PF12937.7 EAU90907.1 - 3.3e-10 39.7 0.1 8.2e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90907.1 - 0.53 10.2 4.6 0.27 11.2 0.8 2.5 2 0 0 2 2 2 0 F-box domain zf-LYAR PF08790.11 EAU90910.1 - 2e-14 53.2 1.3 4.5e-14 52.0 1.3 1.7 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Autophagy_N PF03986.13 EAU90911.2 - 1.6e-42 144.7 0.3 5.7e-42 142.9 0.0 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EAU90911.2 - 7.7e-18 64.8 0.4 1.6e-17 63.8 0.4 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EAU90911.2 - 1.5e-12 46.8 2.9 2.9e-12 45.9 2.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal MDD_C PF18376.1 EAU90912.1 - 4.8e-71 238.4 0.0 6.4e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EAU90912.1 - 2.4e-06 27.7 2.8 5.8e-06 26.5 2.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain F-box-like PF12937.7 EAU90915.2 - 0.00011 22.0 0.3 0.0007 19.4 0.1 2.6 2 0 0 2 2 2 1 F-box-like Pyridoxal_deC PF00282.19 EAU90916.2 - 3.1e-14 52.5 0.0 5.6e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EAU90916.2 - 4.3e-08 32.5 0.0 6.4e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EAU90916.2 - 0.00021 20.6 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EAU90916.2 - 0.001 18.4 0.2 0.0017 17.7 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family MBOAT_2 PF13813.6 EAU90917.2 - 1.5e-19 70.0 6.8 5.6e-19 68.2 6.8 2.1 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RNase_T PF00929.24 EAU90918.1 - 0.0024 18.4 0.0 0.0043 17.6 0.0 1.5 1 1 0 1 1 1 1 Exonuclease CDC27 PF09507.10 EAU90919.2 - 2.7 7.3 31.8 4.5 6.6 31.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Menin PF05053.13 EAU90919.2 - 4.5 5.5 15.6 6.3 5.0 15.6 1.1 1 0 0 1 1 1 0 Menin Macoilin PF09726.9 EAU90919.2 - 8.2 4.8 11.6 11 4.5 11.6 1.1 1 0 0 1 1 1 0 Macoilin family Glyoxalase PF00903.25 EAU90920.2 - 1.9e-23 83.1 0.1 2.2e-23 82.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EAU90920.2 - 2.2e-06 27.9 0.0 3.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EAU90920.2 - 3.6e-05 24.5 0.0 5.8e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EAU90920.2 - 0.0059 16.5 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EAU90920.2 - 0.0093 16.1 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 EAU90920.2 - 0.15 12.1 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Nkap_C PF06047.11 EAU90922.2 - 6.1e-42 141.9 6.7 6.1e-42 141.9 6.7 2.5 2 1 1 3 3 3 1 NF-kappa-B-activating protein C-terminal domain Git3 PF11710.8 EAU90923.2 - 8.3e-09 35.5 9.6 6.8e-08 32.5 9.6 2.1 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 EAU90923.2 - 1.8e-06 27.5 4.7 1.8e-06 27.5 4.7 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 EAU90923.2 - 0.00027 20.4 1.8 0.00045 19.7 1.8 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Oxidored_q3 PF00499.20 EAU90923.2 - 0.016 14.9 1.4 0.046 13.4 1.4 1.7 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Otopetrin PF03189.13 EAU90923.2 - 0.062 12.1 0.9 0.24 10.2 0.5 1.9 2 0 0 2 2 2 0 Otopetrin GPR_Gpa2_C PF11970.8 EAU90923.2 - 0.13 12.3 4.1 0.12 12.4 0.4 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Totivirus_coat PF05518.11 EAU90924.1 - 0.25 9.3 0.6 0.32 9.0 0.6 1.0 1 0 0 1 1 1 0 Totivirus coat protein tRNA-synt_2 PF00152.20 EAU90925.1 - 3e-75 253.2 0.0 3.8e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAU90925.1 - 1.8e-12 47.1 0.0 4.7e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAU90925.1 - 5.4e-08 32.6 0.0 0.0005 19.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ribosomal_60s PF00428.19 EAU90925.1 - 0.45 11.1 7.0 2.4 8.8 7.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein MBOAT_2 PF13813.6 EAU90926.2 - 1.2e-22 80.0 3.3 1.2e-22 80.0 3.3 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family F-box-like PF12937.7 EAU90927.2 - 1.2e-07 31.5 0.3 2.8e-07 30.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90927.2 - 0.029 14.2 0.5 0.029 14.2 0.5 3.4 4 1 0 4 4 4 0 F-box domain F-box_4 PF15966.5 EAU90927.2 - 0.061 13.2 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 F-box IBR PF01485.21 EAU90928.1 - 6.1e-12 45.6 41.3 6.3e-09 35.9 17.1 4.3 3 2 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EAU90928.1 - 7.3e-05 22.7 4.1 7.3e-05 22.7 4.1 3.4 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAU90928.1 - 0.00022 21.0 32.7 0.00035 20.4 5.1 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU90928.1 - 0.00041 20.1 2.1 0.00041 20.1 2.1 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU90928.1 - 0.0033 17.7 5.8 0.0033 17.7 5.8 3.6 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 EAU90928.1 - 2.6 8.1 25.4 0.23 11.5 4.2 3.5 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_6 PF14835.6 EAU90928.1 - 7.6 6.5 18.1 11 5.9 0.7 4.1 4 0 0 4 4 4 0 zf-RING of BARD1-type protein LRR_4 PF12799.7 EAU90929.1 - 1.6 9.2 8.4 33 5.1 0.0 4.8 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) G-alpha PF00503.20 EAU90930.1 - 6.5e-113 377.5 0.0 7.6e-113 377.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU90930.1 - 1.3e-08 34.4 1.3 0.32 10.4 0.1 3.9 4 0 0 4 4 4 3 ADP-ribosylation factor family TniB PF05621.11 EAU90930.1 - 0.0055 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 EAU90930.1 - 0.031 14.0 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EAU90930.1 - 0.05 13.5 0.0 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Gtr1_RagA PF04670.12 EAU90930.1 - 0.076 12.3 1.3 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Ras PF00071.22 EAU90930.1 - 0.12 11.9 0.3 5.5 6.6 0.2 2.2 2 0 0 2 2 2 0 Ras family Na_H_Exchanger PF00999.21 EAU90931.2 - 2.4e-45 154.9 42.7 3.5e-45 154.4 42.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family F-box-like PF12937.7 EAU90932.1 - 0.0033 17.3 4.7 0.038 13.9 4.7 2.4 1 1 0 1 1 1 1 F-box-like IGFL PF14653.6 EAU90934.2 - 0.13 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Insulin growth factor-like family Sec34 PF04136.15 EAU90936.2 - 1e-47 161.7 1.4 2e-47 160.8 1.4 1.5 1 0 0 1 1 1 1 Sec34-like family POX PF07526.11 EAU90936.2 - 0.012 16.1 1.1 1.6 9.3 0.0 3.5 3 0 0 3 3 3 0 Associated with HOX GCN5L1 PF06320.13 EAU90936.2 - 0.1 12.8 0.5 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF4667 PF15700.5 EAU90936.2 - 1 9.4 7.9 0.62 10.1 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4667) F-box-like PF12937.7 EAU90939.1 - 1.4e-09 37.7 0.8 4.5e-09 36.0 0.8 2.0 1 0 0 1 1 1 1 F-box-like CENP-F_leu_zip PF10473.9 EAU90939.1 - 0.021 14.8 2.3 0.039 14.0 2.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 EAU90939.1 - 0.023 13.8 1.4 0.038 13.1 1.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PspA_IM30 PF04012.12 EAU90939.1 - 0.029 13.9 1.0 0.046 13.3 1.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.11 EAU90939.1 - 0.03 13.2 3.4 0.052 12.4 3.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF812 PF05667.11 EAU90939.1 - 0.064 12.1 2.1 0.094 11.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.20 EAU90939.1 - 0.066 13.2 1.3 0.12 12.3 1.3 1.4 1 0 0 1 1 1 0 Prefoldin subunit CENP-H PF05837.12 EAU90939.1 - 0.16 12.4 4.2 0.076 13.4 1.3 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PI3K_P85_iSH2 PF16454.5 EAU90939.1 - 0.18 11.4 3.5 0.32 10.6 3.5 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5082 PF16888.5 EAU90939.1 - 0.28 11.4 3.4 0.52 10.6 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Taxilin PF09728.9 EAU90939.1 - 0.28 10.3 5.1 0.47 9.6 5.1 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein bZIP_1 PF00170.21 EAU90939.1 - 0.54 10.4 9.3 0.18 12.0 4.9 2.4 2 0 0 2 2 2 0 bZIP transcription factor OsmC PF02566.19 EAU90940.1 - 4e-13 49.7 0.0 6.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein MMS1_N PF10433.9 EAU90941.1 - 4.1e-160 533.6 0.0 6.4e-160 533.0 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EAU90941.1 - 5.5e-96 321.7 0.0 2.2e-95 319.7 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MFS_1 PF07690.16 EAU90942.1 - 3.1e-34 118.4 23.3 3.1e-34 118.4 23.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EAU90942.1 - 0.0029 16.5 0.5 0.0029 16.5 0.5 2.0 2 0 0 2 2 2 1 MFS_1 like family F-box-like PF12937.7 EAU90943.2 - 0.0002 21.2 0.4 0.00051 19.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU90944.2 - 5.7e-08 32.5 0.3 1.7e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU90944.2 - 0.002 17.9 0.0 0.0095 15.8 0.0 2.2 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 EAU90945.1 - 2.8e-33 115.3 29.9 4.6e-33 114.6 29.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3273 PF11677.8 EAU90945.1 - 0.025 13.9 1.3 0.059 12.7 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) Topoisom_bac PF01131.20 EAU90946.2 - 3e-98 329.5 0.0 3.9e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EAU90946.2 - 3.6e-19 68.9 0.0 9.1e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.12 EAU90946.2 - 6.4e-18 64.6 10.6 4.9e-15 55.4 5.3 2.8 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.23 EAU90946.2 - 1.1e-14 53.8 14.5 6e-06 26.1 1.5 3.8 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 EAU90946.2 - 0.00014 21.7 9.2 0.05 13.6 0.1 3.7 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 EAU90946.2 - 0.0041 16.9 18.6 0.022 14.6 2.7 3.7 3 0 0 3 3 3 3 Zinc knuckle UTP25 PF06862.12 EAU90947.2 - 2.5e-159 531.0 0.1 3.1e-159 530.7 0.1 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 F-box-like PF12937.7 EAU90948.2 - 0.031 14.2 0.5 0.084 12.8 0.5 1.8 1 0 0 1 1 1 0 F-box-like PC-Esterase PF13839.6 EAU90950.2 - 0.0001 22.2 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DEAD PF00270.29 EAU90951.1 - 5.5e-05 23.0 0.0 7.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.14 EAU90951.1 - 0.18 11.1 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain LRR_8 PF13855.6 EAU90953.2 - 2.9e-46 155.0 67.5 3e-14 52.5 3.5 11.4 7 4 5 12 12 12 7 Leucine rich repeat LRR_4 PF12799.7 EAU90953.2 - 4e-44 147.9 65.6 4.9e-08 33.1 0.8 12.6 9 3 3 12 12 12 11 Leucine Rich repeats (2 copies) PP2C PF00481.21 EAU90953.2 - 1.4e-43 149.4 0.0 2.4e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 EAU90953.2 - 1.2e-22 80.5 0.0 2.2e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EAU90953.2 - 8.7e-09 35.1 22.5 0.012 15.2 0.2 5.5 3 2 2 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 EAU90953.2 - 3.8e-06 26.9 0.3 2.1 8.3 0.0 4.4 3 1 2 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EAU90953.2 - 5.5e-06 26.2 49.8 3.2 8.7 0.5 15.8 16 0 0 16 16 16 3 Leucine Rich Repeat LRR_6 PF13516.6 EAU90953.2 - 0.0047 16.9 50.4 1.4 9.1 0.1 13.0 14 0 0 14 14 14 3 Leucine Rich repeat HSP20 PF00011.21 EAU90954.1 - 2e-24 85.6 0.0 2.7e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAU90954.1 - 2e-11 43.3 0.0 3.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 EAU90954.1 - 0.063 12.6 0.1 0.085 12.2 0.1 1.3 1 1 0 1 1 1 0 Putative adhesin FKBP26_C PF18046.1 EAU90954.1 - 0.078 13.1 0.1 7.5 6.7 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal F-box-like PF12937.7 EAU90955.1 - 4.1e-06 26.6 0.3 1e-05 25.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like SKA2 PF16740.5 EAU90955.1 - 0.095 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Prominin PF05478.11 EAU90955.1 - 0.16 9.9 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 Prominin DUF4349 PF14257.6 EAU90955.1 - 0.3 10.5 0.7 0.55 9.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Totivirus_coat PF05518.11 EAU90957.1 - 0.032 12.3 1.9 0.042 11.9 1.9 1.0 1 0 0 1 1 1 0 Totivirus coat protein Malate_synthase PF01274.22 EAU90958.2 - 5.3e-202 671.7 0.0 6.7e-202 671.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase 30K_MP_C_Ter PF11330.8 EAU90958.2 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 C-Terminal of 30K viral movement proteins CHD5 PF04420.14 EAU90959.1 - 2.1e-56 190.2 4.0 2.6e-56 189.9 4.0 1.1 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_6 PF01441.19 EAU90959.1 - 0.0027 17.8 0.1 0.0034 17.4 0.1 1.1 1 0 0 1 1 1 1 Lipoprotein F-box-like PF12937.7 EAU90960.2 - 6.5e-06 25.9 0.2 2.3e-05 24.2 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90960.2 - 0.027 14.4 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EAU90961.2 - 2.2e-07 30.6 0.1 6.1e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU90961.2 - 0.00056 19.7 0.2 0.0028 17.5 0.2 2.2 1 1 0 1 1 1 1 F-box domain Amidohydro_2 PF04909.14 EAU90963.1 - 8.3e-26 91.4 0.1 1e-25 91.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase FKBP_C PF00254.28 EAU90964.1 - 4e-31 107.2 0.0 4.9e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box-like PF12937.7 EAU90965.1 - 4.3e-06 26.5 0.4 8.9e-06 25.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU90966.2 - 0.00023 21.0 0.4 0.002 18.0 0.1 2.7 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 EAU90967.1 - 0.073 13.4 0.0 0.55 10.6 0.0 2.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU90967.1 - 0.25 12.3 11.0 30 5.7 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF3341 PF11821.8 EAU90968.1 - 0.19 11.3 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) PSCyt3 PF07627.11 EAU90968.1 - 0.32 11.3 3.6 0.99 9.7 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) A1_Propeptide PF07966.12 EAU90968.1 - 6.4 6.8 10.1 1.1 9.2 2.4 2.4 2 0 0 2 2 2 0 A1 Propeptide ResIII PF04851.15 EAU90969.2 - 0.0036 17.3 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EAU90969.2 - 0.0052 16.5 0.1 0.0098 15.6 0.1 1.4 1 1 0 1 1 1 1 SWI2/SNF2 ATPase NB-ARC PF00931.22 EAU90969.2 - 0.034 13.3 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Mg_trans_NIPA PF05653.14 EAU90972.1 - 2.3e-81 273.2 33.3 3e-81 272.8 33.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EAU90972.1 - 6.8e-06 26.3 14.8 6.8e-06 26.3 14.8 3.3 2 1 0 2 2 2 1 EamA-like transporter family U79_P34 PF03064.16 EAU90972.1 - 0.011 15.1 5.5 0.021 14.2 5.5 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Oxysterol_BP PF01237.18 EAU90972.1 - 0.013 14.3 4.5 0.019 13.8 4.5 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein RNA_pol_Rpc4 PF05132.14 EAU90972.1 - 1.6 9.1 7.1 3.9 7.9 7.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Arf PF00025.21 EAU90973.1 - 6.3e-29 100.6 0.0 1.1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EAU90973.1 - 2.7e-10 40.0 0.0 4.7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EAU90973.1 - 3.3e-06 27.3 0.0 6.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU90973.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EAU90973.1 - 8.9e-05 21.9 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU90973.1 - 0.0043 17.1 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cytochrom_C1 PF02167.15 EAU90973.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Methyltransf_16 PF10294.9 EAU90973.1 - 0.19 11.5 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Lysine methyltransferase GCM PF03615.15 EAU90975.2 - 0.00012 22.0 3.4 0.00024 21.0 3.4 1.5 1 0 0 1 1 1 1 GCM motif protein PHD PF00628.29 EAU90975.2 - 0.0047 16.8 5.9 0.01 15.7 5.9 1.6 1 0 0 1 1 1 1 PHD-finger PBP1_TM PF14812.6 EAU90977.2 - 0.0064 16.8 3.2 0.0064 16.8 3.2 3.8 4 1 1 5 5 5 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Imm32 PF15566.6 EAU90977.2 - 0.098 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 32 Nucleo_P87 PF07267.11 EAU90977.2 - 6.7 5.4 8.1 11 4.7 8.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MBOAT_2 PF13813.6 EAU90980.1 - 5.4e-09 36.2 0.1 5.4e-09 36.2 0.1 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 EAU90981.2 - 5.1e-23 81.2 0.6 5.1e-23 81.2 0.6 2.3 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Glyco_tranf_2_3 PF13641.6 EAU90982.2 - 4e-30 105.4 0.0 5.9e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EAU90982.2 - 4.1e-09 36.5 0.0 6.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EAU90982.2 - 7.9e-08 32.0 0.0 4.5e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EAU90982.2 - 0.017 15.0 5.1 0.037 13.9 5.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Choline_kinase PF01633.20 EAU90983.2 - 3.9e-08 33.1 0.0 5.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAU90983.2 - 2.2e-07 31.0 0.0 4.1e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Creatinase_N_2 PF16189.5 EAU90984.2 - 2.3e-39 135.1 0.0 1.7e-38 132.2 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EAU90984.2 - 1.4e-31 109.9 1.0 1.9e-19 70.2 0.0 2.2 1 1 1 2 2 2 2 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EAU90984.2 - 2.7e-22 78.6 1.2 7.1e-22 77.3 1.2 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EAU90984.2 - 2.8e-19 70.1 0.1 1.2e-18 68.0 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain F-box-like PF12937.7 EAU90986.1 - 0.0072 16.2 0.1 0.0072 16.2 0.1 2.7 4 0 0 4 4 4 1 F-box-like MBOAT_2 PF13813.6 EAU90987.2 - 2e-23 82.5 3.2 2.5e-23 82.1 0.4 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RCC1 PF00415.18 EAU90988.1 - 1.7e-51 172.6 15.2 1.9e-09 38.0 0.2 7.6 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAU90988.1 - 2.1e-31 107.1 24.7 1.4e-06 27.9 0.8 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EAU90988.1 - 0.0015 18.3 0.7 1.7 8.3 0.0 3.3 4 0 0 4 4 4 2 TUP1-like enhancer of split Ndc1_Nup PF09531.10 EAU90988.1 - 5.9 5.4 6.4 7.7 5.1 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VPS13 PF16908.5 EAU90989.2 - 0.059 13.2 0.6 0.12 12.2 0.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal YjcZ PF13990.6 EAU90989.2 - 0.41 10.0 3.0 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 YjcZ-like protein FliG_C PF01706.16 EAU90989.2 - 0.75 10.0 4.4 0.88 9.8 0.6 2.9 2 0 0 2 2 2 0 FliG C-terminal domain Baculo_PEP_C PF04513.12 EAU90989.2 - 2.5 8.2 8.7 0.39 10.8 0.5 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EAU90989.2 - 2.8 8.5 7.2 38 4.8 0.0 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Apolipoprotein PF01442.18 EAU90989.2 - 4.9 7.0 12.1 0.88 9.4 4.5 2.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Peptidase_S8 PF00082.22 EAU90992.2 - 5.1e-39 134.3 0.8 7.4e-39 133.8 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EAU90992.2 - 1.6e-27 95.4 0.3 3.3e-27 94.3 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain ORC6 PF05460.13 EAU90992.2 - 0.017 14.4 0.6 0.025 13.9 0.6 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DIOX_N PF14226.6 EAU90993.1 - 3.1e-28 98.9 0.0 4.6e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EAU90993.1 - 2.6e-18 66.4 0.0 5.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec2p PF06428.11 EAU90994.2 - 2.8e-09 36.8 16.2 2.8e-09 36.8 16.2 2.7 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p DUF1664 PF07889.12 EAU90994.2 - 4 7.5 11.1 1.3 9.0 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 EAU90994.2 - 4.9 6.6 11.9 0.11 12.1 3.4 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit HIP1_clath_bdg PF16515.5 EAU90994.2 - 7.3 7.3 20.9 3.8 8.2 12.5 2.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Lipase_GDSL_2 PF13472.6 EAU90995.1 - 2.8e-14 53.9 0.3 3.6e-14 53.5 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU90995.1 - 1.7e-09 37.9 0.0 2.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase F-box-like_2 PF13013.6 EAU90998.2 - 6.8e-05 22.8 0.3 0.00051 20.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like domain eIF3m_C_helix PF18005.1 EAU90998.2 - 0.12 12.1 0.9 0.27 11.0 0.9 1.7 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Sensor PF13796.6 EAU91004.2 - 1.7e-05 24.9 17.2 6.3e-05 23.1 13.7 2.9 1 1 1 2 2 2 2 Putative sensor BCS1_N PF08740.11 EAU91005.2 - 1.1e-27 97.2 6.4 1.1e-27 97.2 6.4 2.2 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 EAU91005.2 - 2.8e-15 56.9 0.0 1.3e-06 28.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EAU91005.2 - 0.00046 19.4 0.0 0.0012 18.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EAU91005.2 - 0.0018 18.7 0.1 0.0018 18.7 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EAU91005.2 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EAU91005.2 - 0.037 14.2 0.3 0.037 14.2 0.3 3.2 2 2 0 2 2 1 0 AAA domain AAA_5 PF07728.14 EAU91005.2 - 0.054 13.5 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TFIIA PF03153.13 EAU91005.2 - 0.1 12.6 21.4 0.2 11.6 21.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Viral_helicase1 PF01443.18 EAU91005.2 - 0.34 10.6 1.3 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EAU91005.2 - 0.54 10.8 5.5 0.93 10.0 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Cwf_Cwc_15 PF04889.12 EAU91005.2 - 1.1 8.9 42.2 6.8 6.3 0.1 2.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RsgA_GTPase PF03193.16 EAU91005.2 - 1.2 9.0 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase adh_short_C2 PF13561.6 EAU91006.2 - 4.9e-56 189.9 1.2 7.3e-56 189.3 1.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU91006.2 - 2.4e-44 151.1 2.6 5.1e-44 150.1 2.6 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU91006.2 - 0.019 14.9 0.1 0.07 13.0 0.1 1.9 1 1 1 2 2 2 0 KR domain CxC5 PF18718.1 EAU91007.1 - 1.6e-35 121.7 5.5 1.6e-35 121.7 5.5 1.9 2 0 0 2 2 2 1 CxC5 like cysteine cluster associated with KDZ transposases CxC6 PF18721.1 EAU91007.1 - 5.7e-21 74.6 4.5 5.7e-21 74.6 4.5 2.7 3 0 0 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases GST_N_2 PF13409.6 EAU91007.1 - 7.3e-05 23.0 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU91007.1 - 0.00019 21.8 0.0 0.00091 19.6 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 EAU91007.1 - 0.13 12.6 0.1 8.7 6.7 0.0 3.3 3 0 0 3 3 3 0 Outer mitochondrial membrane transport complex protein Porph_ging PF09697.10 EAU91008.2 - 0.049 14.2 0.4 0.13 12.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (Porph_ging) Comm PF15957.5 EAU91009.2 - 0.047 14.0 1.8 0.15 12.4 0.0 2.4 2 0 0 2 2 2 0 Commissureless DUF3318 PF11780.8 EAU91009.2 - 0.077 12.9 0.5 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) R3H PF01424.22 EAU91010.2 - 2.7e-12 46.5 0.0 5.9e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EAU91010.2 - 2.7e-06 27.2 1.7 9.1e-06 25.5 1.7 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EAU91010.2 - 0.0073 16.4 0.4 0.0073 16.4 0.4 3.0 3 0 0 3 3 3 1 G-patch domain SR-25 PF10500.9 EAU91010.2 - 0.08 12.5 5.7 0.38 10.3 1.8 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DBR1 PF05011.13 EAU91012.1 - 1.8e-39 135.4 0.0 3.4e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EAU91012.1 - 7.5e-08 33.1 0.4 1.2e-07 32.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU91012.1 - 0.019 15.2 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SPX PF03105.19 EAU91012.1 - 1.2 9.0 5.4 1.6 8.6 5.4 1.2 1 0 0 1 1 1 0 SPX domain DUF373 PF04123.13 EAU91013.2 - 5.7 6.3 15.5 4.3 6.7 6.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) MtaB PF12176.8 EAU91018.2 - 0.033 13.0 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit BAG PF02179.16 EAU91021.1 - 9e-18 64.5 1.2 1.2e-17 64.0 1.2 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EAU91021.1 - 2.5e-06 27.2 0.0 4.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family zf-TRAF PF02176.18 EAU91022.2 - 1.2e-06 29.1 2.4 1.2e-06 29.1 2.4 2.1 2 0 0 2 2 2 1 TRAF-type zinc finger zf-RING_UBOX PF13445.6 EAU91022.2 - 2.1e-06 27.6 1.5 8.1e-06 25.8 1.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAU91022.2 - 6.2e-05 22.8 1.0 6.2e-05 22.8 1.0 2.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU91022.2 - 0.0011 18.8 0.7 0.0011 18.8 0.7 2.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU91022.2 - 0.0017 18.3 0.2 0.0017 18.3 0.2 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 EAU91022.2 - 0.0024 17.7 0.5 0.0067 16.2 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EAU91022.2 - 0.013 15.7 0.7 0.013 15.7 0.7 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Sina PF03145.16 EAU91022.2 - 0.018 15.0 1.8 0.03 14.3 1.8 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-RING_2 PF13639.6 EAU91022.2 - 0.021 15.1 1.1 0.021 15.1 1.1 2.5 3 1 0 3 3 3 0 Ring finger domain zf-TRAF_2 PF15965.5 EAU91022.2 - 0.88 10.1 11.3 0.14 12.7 6.0 2.3 2 1 1 3 3 3 0 TRAF-like zinc-finger DEAD PF00270.29 EAU91023.2 - 3.7e-38 131.0 0.0 6.4e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 EAU91023.2 - 5.6e-18 64.9 0.8 9.9e-18 64.1 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 EAU91023.2 - 7.2e-18 65.0 0.0 4.7e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU91023.2 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sigma70_ner PF04546.13 EAU91023.2 - 0.2 11.5 3.0 0.62 9.9 3.0 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 EAU91023.2 - 0.82 9.3 3.2 0.41 10.3 0.3 2.0 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.12 EAU91023.2 - 1.4 7.0 5.6 2.3 6.3 5.6 1.2 1 0 0 1 1 1 0 Nop14-like family MOZ_SAS PF01853.18 EAU91024.2 - 3.8e-80 267.8 0.1 5.5e-80 267.2 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EAU91024.2 - 1.1e-21 76.1 1.1 2.4e-21 75.1 1.1 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EAU91024.2 - 1.3e-18 66.6 0.0 2.6e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EAU91024.2 - 0.0011 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU91024.2 - 0.0052 17.0 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_Mga PF08280.11 EAU91024.2 - 0.0076 16.3 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain TRADD_N PF09034.10 EAU91025.2 - 0.2 11.7 0.0 0.32 11.1 0.0 1.2 1 0 0 1 1 1 0 TRADD, N-terminal domain LAG1-DNAbind PF09271.11 EAU91026.1 - 3.4e-50 170.6 0.1 5.9e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 EAU91026.1 - 2.1e-19 70.2 0.0 9.1e-18 64.9 0.0 2.7 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF5423 PF17461.2 EAU91026.1 - 0.46 9.3 4.0 1 8.1 4.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DUF4200 PF13863.6 EAU91028.2 - 0.032 14.6 3.2 0.053 13.9 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 EAU91028.2 - 1.1 9.4 8.6 2.2 8.4 8.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 EAU91028.2 - 1.3 9.1 9.0 2.9 8.1 9.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper PAC4 PF16093.5 EAU91029.1 - 3.4e-12 46.4 0.0 4.7e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Put_Phosphatase PF06888.12 EAU91032.1 - 1.3e-51 175.3 0.0 1.4e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 EAU91032.1 - 2.7e-07 31.2 0.1 6.2e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU91032.1 - 0.006 16.9 0.0 0.027 14.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EAU91032.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Hydrolase_3 PF08282.12 EAU91032.1 - 0.057 13.1 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase BSD PF03909.17 EAU91033.1 - 2.8e-20 72.0 0.4 7.9e-14 51.4 0.1 2.5 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EAU91033.1 - 1.5e-18 66.9 0.1 2.8e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Ribosomal_L19e PF01280.20 EAU91034.2 - 0.044 13.9 5.8 0.076 13.1 5.8 1.4 1 1 0 1 1 1 0 Ribosomal protein L19e AP1AR PF15745.5 EAU91034.2 - 0.18 11.4 5.4 0.25 10.9 5.4 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Ribosomal_S9 PF00380.19 EAU91037.2 - 1.9e-43 147.8 0.0 3.3e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRE1 PF08647.11 EAU91038.2 - 5.7e-21 74.4 9.9 5.7e-21 74.4 9.9 9.1 5 3 3 8 8 8 3 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 EAU91038.2 - 0.027 14.5 0.1 0.027 14.5 0.1 6.9 4 2 4 8 8 8 0 Protein of unknown function (DUF1664) Allantoicase PF03561.15 EAU91039.2 - 2.3e-93 309.8 0.0 2.5e-47 160.5 0.0 2.3 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 EAU91039.2 - 4.7e-45 153.7 0.0 7.3e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate lyase Zn_clus PF00172.18 EAU91042.1 - 0.0013 18.8 12.4 0.0024 18.0 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EAU91042.1 - 0.0038 17.2 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PRA1 PF03208.19 EAU91043.2 - 3e-35 120.9 0.6 3.7e-35 120.6 0.6 1.0 1 0 0 1 1 1 1 PRA1 family protein MPS-4 PF17523.2 EAU91043.2 - 0.0053 16.9 0.5 0.011 15.9 0.5 1.5 1 0 0 1 1 1 1 MinK-related peptide, potassium channel accessory sub-unit protein 4 EBP PF05241.12 EAU91043.2 - 0.091 12.2 2.1 0.11 12.0 2.1 1.1 1 0 0 1 1 1 0 Emopamil binding protein CBM_35 PF16990.5 EAU91043.2 - 0.16 12.2 0.0 0.31 11.3 0.0 1.3 1 1 0 1 1 1 0 Carbohydrate binding module (family 35) DUF4131 PF13567.6 EAU91043.2 - 4.9 6.8 8.3 5.1 6.7 6.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) F-box-like PF12937.7 EAU91045.2 - 0.033 14.1 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 F-box-like Rad9 PF04139.13 EAU91046.2 - 6.1e-16 58.6 0.1 9.9e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Rad9 RIBIOP_C PF04950.12 EAU91047.2 - 1.8e-122 408.3 0.1 2.8e-122 407.7 0.1 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EAU91047.2 - 6.4e-16 58.2 0.1 7e-15 54.9 0.0 2.7 2 1 0 2 2 2 1 AARP2CN (NUC121) domain CopG_antitoxin PF12441.8 EAU91047.2 - 0.58 10.7 2.8 0.72 10.4 1.5 1.8 2 0 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system Voltage_CLC PF00654.20 EAU91049.2 - 1.8e-86 290.6 36.3 1.8e-86 290.6 36.3 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EAU91049.2 - 7.2e-15 55.2 0.3 4.8e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain SLATT_1 PF18181.1 EAU91049.2 - 0.15 12.0 1.7 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 Septin PF00735.18 EAU91050.1 - 1.6e-108 362.3 0.4 2.1e-108 361.9 0.0 1.3 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EAU91050.1 - 2.4e-05 24.4 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU91050.1 - 0.0018 17.6 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EAU91050.1 - 0.0021 18.1 2.2 1.7 8.6 0.0 3.1 3 0 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EAU91050.1 - 0.0063 16.1 0.5 0.32 10.5 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 EAU91050.1 - 0.05 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 EAU91050.1 - 0.062 12.3 0.1 0.16 11.0 0.1 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.12 EAU91050.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 EAU91050.1 - 0.15 12.0 5.6 0.14 12.1 0.6 3.0 3 1 0 3 3 3 0 RsgA GTPase adh_short PF00106.25 EAU91051.1 - 2.7e-36 124.9 0.1 3.8e-36 124.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU91051.1 - 4.2e-30 105.0 0.0 7.2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU91051.1 - 0.00033 20.6 0.5 0.0024 17.8 0.5 2.0 1 1 0 1 1 1 1 KR domain DUF1097 PF06496.11 EAU91053.2 - 6.2 6.9 10.7 0.64 10.1 3.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1097) JAKMIP_CC3 PF16034.5 EAU91054.1 - 0.018 15.0 1.2 0.033 14.1 1.2 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain DASH_Dad2 PF08654.10 EAU91054.1 - 0.22 12.0 1.0 4.1 7.9 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 Tmemb_cc2 PF10267.9 EAU91054.1 - 0.45 9.6 2.1 0.84 8.7 1.3 1.7 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Pro_isomerase PF00160.21 EAU91055.2 - 2.4e-49 167.6 0.2 3.6e-49 167.1 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DPBB_1 PF03330.18 EAU91056.1 - 5.6e-05 23.3 0.0 9.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Acetyltransf_1 PF00583.25 EAU91057.2 - 7.7e-07 29.4 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU91057.2 - 6.1e-06 26.2 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU91057.2 - 6.2e-05 23.3 0.2 0.00011 22.5 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Bromodomain PF00439.25 EAU91057.2 - 0.004 17.2 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain FR47 PF08445.10 EAU91057.2 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein TFIIF_alpha PF05793.12 EAU91057.2 - 0.55 8.8 10.7 0.94 8.0 10.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) 2-Hacid_dh_C PF02826.19 EAU91058.2 - 3.7e-46 156.7 0.0 5.5e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAU91058.2 - 2.7e-18 65.9 0.0 3.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAU91058.2 - 9.7e-05 22.6 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF5029 PF16432.5 EAU91058.2 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) NAD_binding_7 PF13241.6 EAU91058.2 - 0.13 12.7 0.1 0.89 10.0 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding EXS PF03124.14 EAU91059.2 - 2.9e-103 345.7 7.7 3.3e-103 345.5 7.7 1.0 1 0 0 1 1 1 1 EXS family zf-C2H2_jaz PF12171.8 EAU91060.2 - 2e-07 31.1 0.1 3.3e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU91060.2 - 5.9e-06 26.5 0.3 9.1e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EAU91060.2 - 0.00017 21.6 0.1 0.00029 20.9 0.1 1.3 1 0 0 1 1 1 1 DBF zinc finger SNRNP27 PF08648.12 EAU91060.2 - 0.0004 20.4 1.2 0.0012 18.9 1.2 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF4637 PF15470.6 EAU91060.2 - 0.036 13.8 0.1 0.036 13.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) zf-C2H2 PF00096.26 EAU91060.2 - 0.04 14.4 0.5 0.067 13.7 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type UNC-79 PF14776.6 EAU91060.2 - 0.056 12.2 0.3 0.084 11.6 0.3 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 zf-C2H2_4 PF13894.6 EAU91060.2 - 0.14 13.1 0.1 0.25 12.3 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger MAS20 PF02064.15 EAU91060.2 - 1.5 8.9 16.4 2.3 8.3 3.9 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor Med19 PF10278.9 EAU91060.2 - 7.9 6.4 14.9 3.7 7.4 2.8 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 tRNA-synt_1 PF00133.22 EAU91061.2 - 6.6e-225 747.9 0.0 1.6e-224 746.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EAU91061.2 - 1.2e-26 93.4 0.2 2.2e-26 92.6 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EAU91061.2 - 2.7e-14 52.7 0.1 6.3e-06 25.2 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EAU91061.2 - 0.01 15.2 0.0 0.048 13.0 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Arf PF00025.21 EAU91062.2 - 1.9e-34 118.6 0.0 2.7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EAU91062.2 - 3.2e-11 43.0 0.0 2.1e-06 27.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EAU91062.2 - 2.7e-10 40.5 0.0 5.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU91062.2 - 1.3e-06 28.1 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EAU91062.2 - 4.7e-06 26.2 0.0 8.7e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAU91062.2 - 5.5e-06 25.9 0.0 7.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU91062.2 - 1.3e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EAU91062.2 - 0.0031 18.0 0.0 0.0049 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EAU91062.2 - 0.0035 16.9 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EAU91062.2 - 0.0043 17.6 0.1 0.008 16.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EAU91062.2 - 0.0095 16.2 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU91062.2 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EAU91062.2 - 0.025 14.2 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase cobW PF02492.19 EAU91062.2 - 0.035 13.7 0.1 0.37 10.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EAU91062.2 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU91062.2 - 0.052 13.9 0.6 0.096 13.1 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EAU91062.2 - 0.053 13.1 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EAU91062.2 - 0.061 13.2 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EAU91062.2 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EAU91062.2 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU91062.2 - 0.16 12.5 0.4 0.27 11.8 0.3 1.7 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.21 EAU91063.2 - 3.2e-23 81.8 25.3 6.8e-15 55.2 10.5 3.1 4 0 0 4 4 4 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 EAU91063.2 - 0.1 13.0 1.4 2.3 8.7 0.6 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.24 EAU91063.2 - 1 9.0 7.7 0.17 11.5 1.8 2.6 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CUE PF02845.16 EAU91064.2 - 3.5e-08 33.0 0.0 5.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain SET PF00856.28 EAU91065.1 - 7.8e-15 55.7 1.3 2.3e-14 54.2 0.1 2.3 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EAU91065.1 - 1.4e-10 41.9 0.3 4.7e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding PPL5 PF18168.1 EAU91065.1 - 0.29 10.4 4.6 0.56 9.4 4.6 1.4 1 0 0 1 1 1 0 Prim-pol family 5 NOA36 PF06524.12 EAU91065.1 - 6.1 6.1 15.5 11 5.2 15.5 1.3 1 0 0 1 1 1 0 NOA36 protein Metallophos PF00149.28 EAU91066.2 - 1.9e-29 103.6 0.0 2.4e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAU91066.2 - 0.1 13.0 0.9 0.24 11.9 0.9 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-CCCH PF00642.24 EAU91068.1 - 5.3e-09 35.8 2.7 1.2e-08 34.6 2.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EAU91068.1 - 3.7e-08 33.1 4.7 6.7e-08 32.3 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU91068.1 - 2.7e-07 30.4 7.8 4.7e-07 29.6 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EAU91068.1 - 6.5e-06 26.1 8.8 1.3e-05 25.1 8.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAU91068.1 - 1.9e-05 24.4 8.2 3.4e-05 23.6 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU91068.1 - 4.4e-05 23.2 9.0 8.8e-05 22.3 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 EAU91068.1 - 6.1e-05 22.9 4.3 0.00012 22.0 4.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_10 PF16685.5 EAU91068.1 - 0.00013 22.0 2.8 0.0003 20.9 2.8 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 EAU91068.1 - 0.00015 22.1 6.9 0.00026 21.2 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 EAU91068.1 - 0.0023 17.7 2.9 0.0045 16.8 2.9 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3HC4_4 PF15227.6 EAU91068.1 - 0.0028 17.8 7.0 0.0066 16.6 7.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EAU91068.1 - 0.022 14.6 6.5 0.042 13.7 6.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L34e PF01199.18 EAU91068.1 - 1.4 9.3 4.3 0.82 10.0 1.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L34e zf-RanBP PF00641.18 EAU91068.1 - 2.7 7.4 7.8 0.06 12.7 1.2 1.7 2 0 0 2 2 1 0 Zn-finger in Ran binding protein and others C1_2 PF03107.16 EAU91068.1 - 3.1 8.2 6.5 2.1 8.7 2.7 2.3 1 1 1 2 2 2 0 C1 domain bZIP_2 PF07716.15 EAU91069.1 - 8.2e-10 38.6 13.2 8.2e-10 38.6 13.2 2.0 2 0 0 2 2 2 1 Basic region leucine zipper TFIIA PF03153.13 EAU91069.1 - 0.0025 17.9 12.3 0.0038 17.3 12.3 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.21 EAU91069.1 - 0.0041 17.2 10.9 0.0041 17.2 10.9 2.8 3 1 0 3 3 3 1 bZIP transcription factor Shugoshin_N PF07558.11 EAU91069.1 - 0.014 15.3 0.2 0.023 14.6 0.2 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 EAU91069.1 - 0.17 12.2 0.4 0.41 11.0 0.4 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family PAT1 PF09770.9 EAU91069.1 - 0.41 8.9 12.7 0.63 8.2 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.6 EAU91069.1 - 1.6 7.5 7.2 2.4 6.9 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 EAU91069.1 - 3.1 6.4 11.0 4.4 5.9 11.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup bZIP_Maf PF03131.17 EAU91069.1 - 9.7 6.8 11.3 0.52 10.9 3.6 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor LysM PF01476.20 EAU91071.1 - 0.00019 21.4 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain DUF3524 PF12038.8 EAU91072.2 - 0.11 12.3 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) GLTP PF08718.11 EAU91073.1 - 3.4e-45 154.0 0.1 5e-45 153.4 0.1 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) tRNA-synt_1e PF01406.19 EAU91074.2 - 1.6e-119 398.7 0.1 2.4e-119 398.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EAU91074.2 - 9.2e-08 31.2 0.3 1.1e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EAU91074.2 - 1.2e-06 27.1 0.0 6.3e-06 24.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 EAU91074.2 - 0.0038 16.2 0.0 0.4 9.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Gti1_Pac2 PF09729.9 EAU91075.2 - 8.9e-29 100.9 9.2 8e-26 91.2 2.0 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 EAU91077.2 - 2.3e-18 66.9 8.9 1.9e-17 64.0 0.0 3.4 2 2 1 3 3 3 2 Gti1/Pac2 family TFIIA PF03153.13 EAU91078.2 - 6.6e-48 164.7 15.1 3.3e-34 119.6 0.0 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF4692 PF15763.5 EAU91078.2 - 0.85 10.1 4.1 1.6 9.2 4.1 1.5 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) IATP PF04568.12 EAU91079.2 - 0.023 15.1 2.7 0.044 14.2 2.7 1.5 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP BRO1 PF03097.18 EAU91080.1 - 4.4e-22 78.4 0.0 6.5e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain DUF5355 PF17306.2 EAU91080.1 - 0.12 11.4 0.1 0.77 8.7 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5355) PIG-U PF06728.13 EAU91081.2 - 3.6e-106 355.4 28.2 4.4e-106 355.2 28.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EAU91081.2 - 0.42 10.3 10.1 0.035 13.8 4.3 2.0 2 0 0 2 2 2 0 8TM Microsporidial transmembrane domain PALP PF00291.25 EAU91082.2 - 5.7e-53 180.2 0.0 1.8e-26 93.2 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme CoA_binding_2 PF13380.6 EAU91083.1 - 4.3e-29 101.4 0.0 5.2e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Glyco_hydro_18 PF00704.28 EAU91084.2 - 1.6e-44 152.9 0.0 2e-43 149.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4849 PF16141.5 EAU91084.2 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 zf-C2H2 PF00096.26 EAU91085.1 - 7.5e-12 45.0 14.7 0.00036 20.8 0.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU91085.1 - 1.6e-08 34.6 11.8 0.0045 17.7 0.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU91085.1 - 2.2e-06 27.8 5.6 0.00028 21.2 0.7 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EAU91085.1 - 1.6e-05 25.1 8.6 0.05 13.9 0.8 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU91085.1 - 0.0014 18.9 7.6 0.017 15.5 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Fer4_9 PF13187.6 EAU91085.1 - 0.11 12.6 1.0 0.25 11.6 1.0 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-C2H2_6 PF13912.6 EAU91085.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EAU91085.1 - 0.83 10.0 4.5 7.2 7.0 5.0 1.9 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-BED PF02892.15 EAU91085.1 - 1 9.5 6.0 0.15 12.1 1.2 2.0 2 0 0 2 2 2 0 BED zinc finger C1_4 PF07975.12 EAU91085.1 - 4.2 7.7 6.1 24 5.2 4.1 2.3 1 1 1 2 2 2 0 TFIIH C1-like domain FAM176 PF14851.6 EAU91085.1 - 8.1 6.1 21.0 3.4 7.3 6.1 3.2 3 0 0 3 3 3 0 FAM176 family Mito_carr PF00153.27 EAU91086.1 - 3.8e-63 209.4 4.2 1.2e-20 73.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 EAU91087.2 - 1.2e-05 25.1 0.4 5.8e-05 22.9 0.4 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU91087.2 - 0.055 13.4 0.3 9.3 6.3 0.0 2.6 2 0 0 2 2 2 0 F-box domain DUF3844 PF12955.7 EAU91088.1 - 4e-32 110.5 3.9 6e-32 109.9 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Gti1_Pac2 PF09729.9 EAU91089.2 - 1.4e-28 100.2 1.1 1.5e-25 90.3 0.0 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family Glutaredoxin PF00462.24 EAU91091.1 - 0.0083 16.3 0.0 0.04 14.1 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin O-FucT PF10250.9 EAU91092.2 - 1e-13 51.8 0.0 1.6e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Thioredoxin_8 PF13905.6 EAU91092.2 - 0.099 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Glyco_transf_11 PF01531.16 EAU91092.2 - 0.11 11.6 0.0 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 11 O-FucT PF10250.9 EAU91093.2 - 1.7e-14 54.3 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 EAU91093.2 - 0.095 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 CMAS PF02353.20 EAU91094.2 - 3.1e-26 92.3 0.0 3.7e-25 88.7 0.0 2.2 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EAU91094.2 - 4.7e-11 42.7 0.0 7.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU91094.2 - 3e-10 40.7 0.0 7.5e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU91094.2 - 1.9e-08 34.8 0.0 6.3e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU91094.2 - 1.9e-06 27.5 0.0 3.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EAU91094.2 - 2.2e-06 28.3 0.0 6.6e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EAU91094.2 - 4.7e-05 22.9 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 EAU91094.2 - 0.00013 21.4 0.0 0.00039 19.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 EAU91094.2 - 0.0013 17.8 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 EAU91094.2 - 0.002 17.8 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 EAU91094.2 - 0.0035 17.2 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 EAU91094.2 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NodS PF05401.11 EAU91094.2 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EAU91094.2 - 0.016 15.2 0.0 0.036 14.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EAU91094.2 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EAU91094.2 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bax1-I PF01027.20 EAU91095.1 - 1.2e-49 169.0 24.5 1.4e-49 168.8 24.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 EAU91095.1 - 9.8e-06 25.3 12.0 1.5e-05 24.7 12.0 1.3 1 1 0 1 1 1 1 Bax inhibitor 1 like DUF1761 PF08570.10 EAU91095.1 - 8.5 6.7 14.4 0.23 11.7 4.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) Sigma70_ner PF04546.13 EAU91096.2 - 0.036 13.9 2.1 0.066 13.1 2.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TSC22 PF01166.18 EAU91096.2 - 0.14 12.5 1.7 0.33 11.3 1.7 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family HAD_2 PF13419.6 EAU91097.1 - 2.3e-22 80.0 0.0 3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU91097.1 - 2.5e-13 50.8 0.0 1.1e-12 48.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU91097.1 - 9.2e-06 25.6 0.0 7.7e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EAU91097.1 - 0.00083 19.4 0.0 0.075 13.1 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EAU91097.1 - 0.028 14.8 0.0 0.041 14.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EAU91097.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Glutaredoxin PF00462.24 EAU91098.2 - 1e-12 48.1 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EAU91098.2 - 0.033 14.6 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Esterase_phd PF10503.9 EAU91099.1 - 1.2e-21 77.2 0.5 1.6e-21 76.8 0.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EAU91099.1 - 1.2e-12 47.6 13.2 1.2e-12 47.6 13.2 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EAU91099.1 - 2.6e-08 33.6 0.8 5.1e-08 32.6 0.8 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EAU91099.1 - 0.012 15.2 0.9 0.031 13.9 0.9 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 EAU91099.1 - 0.049 13.5 0.2 0.081 12.8 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EAU91099.1 - 0.052 13.4 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Toxin_7 PF05980.12 EAU91099.1 - 5.7 7.3 11.2 13 6.1 11.2 1.7 1 0 0 1 1 1 0 Toxin 7 TPR_2 PF07719.17 EAU91100.2 - 1.8e-30 102.6 34.2 0.0037 17.3 0.0 13.7 13 1 1 14 14 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 EAU91100.2 - 2.2e-26 92.2 29.8 0.0013 19.2 0.0 11.6 8 2 3 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 EAU91100.2 - 8e-22 76.1 37.5 9.3e-05 22.1 0.0 13.2 15 1 1 16 16 15 6 Tetratricopeptide repeat TPR_8 PF13181.6 EAU91100.2 - 2.5e-19 67.8 20.3 0.0027 17.8 0.0 11.7 12 1 1 13 13 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAU91100.2 - 5.1e-19 68.4 41.3 0.00014 22.0 0.3 10.0 8 2 3 11 11 10 7 Tetratricopeptide repeat TPR_6 PF13174.6 EAU91100.2 - 4.6e-16 58.3 28.6 0.0013 19.2 0.0 13.9 13 1 1 14 14 14 3 Tetratricopeptide repeat TPR_14 PF13428.6 EAU91100.2 - 2.7e-13 49.5 45.6 0.1 13.5 0.0 14.6 12 3 4 16 16 14 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAU91100.2 - 3e-12 47.0 34.6 0.039 14.6 0.0 10.0 9 1 2 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 EAU91100.2 - 6.7e-10 38.3 21.6 0.16 12.1 0.1 10.0 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAU91100.2 - 1.8e-05 24.3 15.7 1.2 8.9 0.0 8.4 9 1 1 10 10 10 3 TPR repeat TPR_17 PF13431.6 EAU91100.2 - 4.6e-05 23.5 16.5 8.1 7.1 0.0 11.0 12 1 1 13 13 13 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU91100.2 - 8.2e-05 22.8 19.7 0.18 12.0 0.3 6.3 6 1 1 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EAU91100.2 - 0.00043 20.1 41.4 0.55 10.2 0.1 11.3 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 EAU91100.2 - 0.00098 19.5 13.5 3.1 8.7 3.9 7.2 6 0 0 6 6 5 1 Tetratricopeptide repeat Mic1 PF07035.12 EAU91100.2 - 0.071 12.8 0.9 0.81 9.4 0.3 2.6 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like PPR_2 PF13041.6 EAU91100.2 - 0.11 12.7 0.2 29 5.0 0.1 3.4 2 0 0 2 2 2 0 PPR repeat family HemY_N PF07219.13 EAU91100.2 - 2 8.7 12.2 0.16 12.2 2.6 3.8 4 0 0 4 4 4 0 HemY protein N-terminus Ribosomal_S2 PF00318.20 EAU91101.1 - 1.7e-29 102.6 0.3 6.7e-15 54.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EAU91101.1 - 3e-09 38.1 9.2 5.3e-09 37.3 9.2 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus SGL PF08450.12 EAU91102.2 - 1.6e-08 34.4 0.1 2.4e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EAU91102.2 - 2.2e-05 24.6 0.0 6.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Arylesterase DUF1942 PF09167.11 EAU91102.2 - 0.032 14.2 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Peptidase_C1_2 PF03051.15 EAU91103.1 - 3.9e-153 510.3 0.0 4.6e-153 510.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EAU91103.1 - 2.8e-07 30.9 0.0 0.028 14.5 0.0 2.6 3 0 0 3 3 3 2 Papain family cysteine protease Pyrid_oxidase_2 PF13883.6 EAU91103.1 - 0.13 12.2 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Phage_portal_2 PF05136.13 EAU91103.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein, lambda family VID27 PF08553.10 EAU91104.1 - 0.039 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain TauD PF02668.16 EAU91105.2 - 6.8e-60 203.1 0.2 8.2e-60 202.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DnaJ PF00226.31 EAU91107.2 - 4.3e-13 49.2 0.1 7.7e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain HlyIII PF03006.20 EAU91108.1 - 3.5e-36 125.0 27.2 3e-35 122.0 27.2 2.1 1 1 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.18 EAU91108.1 - 9.8e-05 22.3 1.0 0.0044 16.9 1.7 2.7 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain Cupin_4 PF08007.12 EAU91108.1 - 0.047 13.1 0.2 2.6 7.4 0.2 2.2 1 1 1 2 2 2 0 Cupin superfamily protein DUF4795 PF16043.5 EAU91108.1 - 0.086 12.4 1.0 0.14 11.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TRP PF06011.12 EAU91109.2 - 2.3e-72 244.0 11.9 3.2e-72 243.6 11.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EAU91109.2 - 2.7e-25 89.4 0.1 5.7e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 ML-like domain TMEMspv1-c74-12 PF11044.8 EAU91109.2 - 2 8.5 3.2 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein OSCP PF00213.18 EAU91110.1 - 5.9e-42 143.7 2.7 6.8e-42 143.5 2.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Peptidase_S46 PF10459.9 EAU91110.1 - 0.00016 20.5 0.1 0.00017 20.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase S46 ICMT PF04140.14 EAU91111.1 - 1.2e-13 51.2 0.0 1e-12 48.3 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAU91111.1 - 1.7e-10 41.2 0.2 1.4e-09 38.3 0.2 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EAU91111.1 - 1.6e-05 23.9 0.0 2.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Abhydrolase_2 PF02230.16 EAU91112.2 - 1.2e-32 113.5 0.0 5.2e-32 111.4 0.0 1.8 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EAU91112.2 - 0.0045 16.3 0.0 0.022 14.0 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EAU91112.2 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.7 EAU91112.2 - 0.018 15.7 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EAU91112.2 - 0.044 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 EAU91112.2 - 0.069 13.1 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 EAU91112.2 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 EAU91112.2 - 0.14 11.8 0.0 0.27 10.9 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Asp PF00026.23 EAU91113.2 - 1.4e-69 234.9 0.0 1.9e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU91113.2 - 1e-10 42.1 0.9 1.2e-06 28.8 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EAU91113.2 - 0.001 19.7 0.6 0.004 17.8 0.2 2.2 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EAU91113.2 - 0.0067 16.2 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Ephrin_rec_like PF07699.13 EAU91114.1 - 1.3e-17 63.2 45.3 2.3e-06 27.3 6.2 5.5 3 2 2 5 5 5 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EAU91114.1 - 0.043 14.2 4.7 0.043 14.2 4.7 6.3 4 1 1 6 6 6 0 TNFR/NGFR cysteine-rich region CUE PF02845.16 EAU91115.1 - 0.0014 18.3 0.1 0.0085 15.8 0.1 2.4 2 1 0 2 2 2 1 CUE domain Glyco_hydro_16 PF00722.21 EAU91116.1 - 6.1e-17 61.6 0.0 9.9e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DNase_NucA_NucB PF14040.6 EAU91117.2 - 3.5e-11 43.5 0.7 6.9e-11 42.5 0.7 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB DUF4097 PF13349.6 EAU91117.2 - 0.38 10.1 2.2 0.65 9.3 0.6 2.2 2 1 0 2 2 2 0 Putative adhesin Methyltransf_25 PF13649.6 EAU91119.2 - 1.5e-13 51.3 0.0 3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU91119.2 - 3.6e-12 46.3 0.1 5.9e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAU91119.2 - 1.1e-11 44.7 0.0 1.7e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EAU91119.2 - 3.7e-10 40.3 0.0 9.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU91119.2 - 3.3e-08 33.5 0.0 2.2e-07 30.9 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EAU91119.2 - 7.4e-08 31.7 0.0 1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 EAU91119.2 - 5.1e-07 30.4 0.0 1.1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EAU91119.2 - 6e-07 29.0 0.0 9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EAU91119.2 - 1.2e-06 28.1 0.0 2.1e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EAU91119.2 - 1.8e-05 24.2 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EAU91119.2 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EAU91119.2 - 0.00058 19.6 0.1 0.0011 18.8 0.1 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EAU91119.2 - 0.00081 18.8 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EAU91119.2 - 0.00087 19.3 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAU91119.2 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EAU91119.2 - 0.013 16.5 0.0 0.03 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EAU91119.2 - 0.015 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 EAU91119.2 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2367 PF10164.9 EAU91120.1 - 6.7e-08 33.0 2.2 8.7e-08 32.6 2.1 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-HIT PF04438.16 EAU91120.1 - 0.11 12.4 1.0 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 HIT zinc finger Methyltransf_16 PF10294.9 EAU91121.1 - 7.8e-06 25.7 0.0 0.0044 16.8 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_31 PF13847.6 EAU91121.1 - 0.17 11.6 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Na_Pi_cotrans PF02690.15 EAU91124.1 - 0.16 12.1 7.9 1.7 8.8 7.9 2.0 1 1 0 1 1 1 0 Na+/Pi-cotransporter ECF_trnsprt PF12822.7 EAU91124.1 - 0.51 10.4 11.4 0.65 10.1 11.4 1.1 1 0 0 1 1 1 0 ECF transporter, substrate-specific component RseC_MucC PF04246.12 EAU91124.1 - 0.71 9.8 6.7 0.59 10.1 4.2 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC CPSF73-100_C PF11718.8 EAU91125.2 - 1.9e-66 223.7 0.2 3.2e-66 223.0 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EAU91125.2 - 3.9e-29 101.2 0.0 1.1e-28 99.7 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EAU91125.2 - 2.1e-18 67.1 0.3 2.1e-18 67.1 0.3 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EAU91125.2 - 1.2e-17 64.0 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EAU91125.2 - 1.1e-16 60.6 0.6 2.3e-16 59.5 0.1 1.8 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EAU91125.2 - 5.5e-07 29.3 1.3 6.8e-06 25.7 0.5 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EAU91125.2 - 7.1e-06 26.0 0.1 7.1e-06 26.0 0.1 2.9 3 1 0 3 3 3 1 Beta-lactamase superfamily domain SOGA PF11365.8 EAU91127.2 - 0.00073 20.6 2.4 0.014 16.5 0.2 2.7 2 0 0 2 2 2 1 Protein SOGA TauD PF02668.16 EAU91128.2 - 9.4e-53 179.7 0.1 1.2e-52 179.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lum_binding PF00677.17 EAU91128.2 - 0.17 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Lumazine binding domain SUR7 PF06687.12 EAU91129.2 - 6.9e-11 42.2 9.9 1.2e-09 38.2 9.9 2.1 1 1 0 1 1 1 1 SUR7/PalI family DUF998 PF06197.13 EAU91129.2 - 0.28 10.7 16.0 1.9 8.0 9.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF998) TMEM132D_C PF15706.5 EAU91129.2 - 0.29 10.9 1.2 20 5.1 0.2 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Oxidored_q2 PF00420.24 EAU91129.2 - 5.6 6.7 10.4 8.3 6.1 4.4 3.1 1 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PhyH PF05721.13 EAU91131.2 - 1.3e-47 162.8 0.0 1.7e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) BRCT_2 PF16589.5 EAU91132.2 - 7.5e-11 42.3 0.0 2.7e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EAU91132.2 - 0.0003 21.0 0.0 0.00078 19.7 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 EAU91132.2 - 0.044 14.2 0.0 0.085 13.2 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Zip PF02535.22 EAU91132.2 - 6 6.0 5.0 10 5.2 5.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_63 PF03200.16 EAU91136.1 - 2.6e-06 26.5 12.3 3.9e-05 22.6 0.5 4.4 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain RhoGAP PF00620.27 EAU91137.2 - 8.9e-29 100.3 0.0 1.6e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mito_carr PF00153.27 EAU91139.1 - 3.8e-70 231.9 8.9 2.2e-25 88.4 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAU91139.1 - 0.0012 18.1 0.4 0.78 8.8 0.0 3.1 2 1 1 3 3 3 2 Gammaproteobacterial serine protease CE2_N PF17996.1 EAU91141.2 - 0.00015 21.7 0.0 0.47 10.5 0.0 2.6 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Amnionless PF14828.6 EAU91141.2 - 0.0016 17.4 0.0 0.0036 16.2 0.0 1.5 2 0 0 2 2 2 1 Amnionless CE2_N PF17996.1 EAU91142.2 - 0.0068 16.4 0.0 3.7 7.6 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal VSP PF03302.13 EAU91142.2 - 0.0072 15.2 0.2 0.01 14.8 0.2 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 EAU91142.2 - 0.15 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Podoplanin Mid1 PF12929.7 EAU91143.2 - 4.9e-62 210.5 0.0 8.1e-62 209.8 0.0 1.3 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EAU91143.2 - 0.00023 21.8 2.6 0.04 14.5 0.3 2.4 2 0 0 2 2 2 2 Fz domain Pur_ac_phosph_N PF16656.5 EAU91143.2 - 0.17 12.5 0.0 0.37 11.4 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Lipase_3 PF01764.25 EAU91144.2 - 3.5e-27 95.0 0.1 6.1e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EAU91144.2 - 0.00028 21.6 0.0 0.00033 21.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EAU91144.2 - 0.0033 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EAU91144.2 - 0.004 16.7 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EAU91144.2 - 0.0065 15.8 0.1 0.0099 15.2 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EAU91144.2 - 0.013 15.2 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EAU91144.2 - 0.017 14.7 0.2 0.034 13.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Esterase PF00756.20 EAU91144.2 - 0.024 14.3 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Putative esterase SWIRM PF04433.17 EAU91145.2 - 8.8e-11 42.0 0.0 2.1e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EAU91145.2 - 1.2e-10 41.3 0.1 2.9e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU91145.2 - 2.4e-05 24.5 0.1 7.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 EAU91145.2 - 0.035 13.9 8.4 0.089 12.6 8.4 1.7 1 1 0 1 1 1 0 Zinc finger, ZZ type Ins_beta PF03488.14 EAU91145.2 - 0.35 10.9 2.8 0.83 9.7 2.8 1.6 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type DUF1757 PF08560.10 EAU91146.1 - 0.052 13.6 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) DUF4234 PF14018.6 EAU91146.1 - 0.094 12.8 0.2 0.24 11.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF1772 PF08592.11 EAU91146.1 - 0.38 11.1 6.4 1.6 9.0 2.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2157 PF09925.9 EAU91147.2 - 0.00024 20.9 1.7 0.00024 20.9 1.7 2.5 2 2 0 2 2 2 1 Predicted membrane protein (DUF2157) FA_desaturase PF00487.24 EAU91147.2 - 0.029 14.2 3.0 0.06 13.2 3.0 1.5 1 0 0 1 1 1 0 Fatty acid desaturase DUF2079 PF09852.9 EAU91147.2 - 0.044 12.6 2.4 0.038 12.9 0.4 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2079) PepSY_TM PF03929.16 EAU91147.2 - 0.075 12.7 5.1 0.9 9.1 3.2 2.2 1 1 1 2 2 2 0 PepSY-associated TM region Chs7 PF12271.8 EAU91147.2 - 0.078 12.3 1.9 0.88 8.9 0.0 2.3 2 0 0 2 2 2 0 Chitin synthase export chaperone DUF1129 PF06570.11 EAU91147.2 - 0.28 10.7 3.6 0.12 11.8 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) FtsK_4TM PF13491.6 EAU91147.2 - 0.31 10.7 6.8 0.4 10.4 0.2 2.7 3 0 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE DUF4386 PF14329.6 EAU91147.2 - 1.1 9.0 12.8 0.05 13.5 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) DUF998 PF06197.13 EAU91147.2 - 1.4 8.5 11.9 0.91 9.1 7.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF1772 PF08592.11 EAU91147.2 - 1.5 9.1 12.4 2 8.7 7.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) DUF4131 PF13567.6 EAU91147.2 - 9.5 5.8 11.2 19 4.8 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF747 PF05346.11 EAU91148.2 - 3e-116 388.4 3.5 4.3e-116 387.9 3.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family HK PF02110.15 EAU91149.1 - 3.8e-76 255.7 2.9 9.9e-76 254.4 2.9 1.7 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EAU91149.1 - 2.6e-56 189.8 0.2 2.6e-56 189.8 0.2 2.1 2 1 1 3 3 3 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 EAU91149.1 - 0.00014 21.3 0.0 0.00054 19.4 0.0 2.0 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase QRPTase_C PF01729.19 EAU91149.1 - 0.0054 16.5 0.5 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Herpes_pp38 PF04846.13 EAU91149.1 - 0.012 15.5 0.9 0.038 13.9 0.9 1.8 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein BTB PF00651.31 EAU91151.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TP6A_N PF04406.14 EAU91152.2 - 5.1e-21 74.4 0.1 1.9e-20 72.6 0.0 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase F-box-like PF12937.7 EAU91153.1 - 2.3e-05 24.2 0.1 2.3e-05 24.2 0.1 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EAU91153.1 - 0.022 15.2 3.2 4.2 7.9 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) EphA2_TM PF14575.6 EAU91154.2 - 0.0056 17.5 0.0 0.018 15.9 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 EAU91154.2 - 0.01 16.5 1.3 0.018 15.7 0.0 2.1 2 1 1 3 3 3 0 Chitin synthesis regulation, resistance to Congo red FAM176 PF14851.6 EAU91154.2 - 0.048 13.3 0.0 7.1 6.3 0.0 2.9 3 0 0 3 3 3 0 FAM176 family Adeno_E3_CR2 PF02439.15 EAU91154.2 - 0.13 12.0 0.9 0.22 11.3 0.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AAA_22 PF13401.6 EAU91155.1 - 4.4e-10 40.0 0.1 1.4e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EAU91155.1 - 1.2e-09 38.4 0.1 2.6e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU91155.1 - 2.6e-09 37.7 0.5 2.6e-09 37.7 0.5 3.1 4 1 0 4 4 1 1 AAA ATPase domain AAA PF00004.29 EAU91155.1 - 3.5e-08 34.0 0.1 1e-07 32.4 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EAU91155.1 - 6.5e-05 22.4 0.0 0.00018 21.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial TniB protein Zeta_toxin PF06414.12 EAU91155.1 - 9.3e-05 21.8 0.0 0.00023 20.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 EAU91155.1 - 0.00052 19.3 0.1 0.00092 18.5 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 EAU91155.1 - 0.00068 20.0 0.2 0.0019 18.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU91155.1 - 0.00083 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAU91155.1 - 0.00093 18.3 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RuvB_N PF05496.12 EAU91155.1 - 0.0012 18.6 0.1 0.033 13.9 0.0 2.5 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EAU91155.1 - 0.0013 18.7 0.0 0.0036 17.3 0.0 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EAU91155.1 - 0.0027 17.7 0.1 0.0089 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EAU91155.1 - 0.0034 16.7 0.0 0.0061 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EAU91155.1 - 0.0058 16.2 0.1 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region KAP_NTPase PF07693.14 EAU91155.1 - 0.0059 15.9 0.3 0.014 14.7 0.3 1.6 1 1 0 1 1 1 1 KAP family P-loop domain PIF1 PF05970.14 EAU91155.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase cobW PF02492.19 EAU91155.1 - 0.018 14.6 0.2 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 EAU91155.1 - 0.021 14.5 0.1 0.064 13.0 0.0 1.8 2 1 0 2 2 1 0 Sigma-54 interaction domain DUF815 PF05673.13 EAU91155.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EAU91155.1 - 0.03 14.2 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 NTPase TIP49 PF06068.13 EAU91155.1 - 0.04 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ResIII PF04851.15 EAU91155.1 - 0.056 13.4 0.1 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EAU91155.1 - 0.061 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EAU91155.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase Torsin PF06309.11 EAU91155.1 - 0.11 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Torsin DnaB_C PF03796.15 EAU91155.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EAU91155.1 - 0.17 11.6 2.3 1.9 8.2 0.3 2.6 2 1 0 2 2 2 0 IstB-like ATP binding protein Mcl1_mid PF12341.8 EAU91158.2 - 2.2e-82 276.8 0.0 1e-81 274.5 0.0 2.1 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EAU91158.2 - 2.7e-15 56.5 15.9 0.00021 22.0 0.0 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU91158.2 - 7.8e-11 42.1 0.2 0.013 15.7 0.0 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EAU91158.2 - 0.089 11.1 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz RrnaAD PF00398.20 EAU91159.1 - 3e-20 72.4 0.0 5.3e-20 71.6 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Git3 PF11710.8 EAU91160.2 - 7.5e-09 35.7 6.7 1.6e-08 34.6 6.7 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EAU91160.2 - 0.00077 19.5 0.3 0.0035 17.4 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Sulfate_transp PF00916.20 EAU91160.2 - 0.024 13.4 2.8 1.7 7.3 0.1 2.4 2 1 0 2 2 2 0 Sulfate permease family Glyoxal_oxid_N PF07250.11 EAU91161.1 - 1.8e-30 105.9 0.0 1.3e-23 83.4 0.0 3.6 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EAU91161.1 - 2.8e-23 82.0 0.0 5.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 EAU91161.1 - 0.00049 20.1 2.0 1.8 8.7 0.1 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Pkinase PF00069.25 EAU91162.2 - 2.9e-19 69.4 0.0 4.6e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91162.2 - 4.4e-14 52.4 0.0 3.4e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EAU91162.2 - 0.033 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.7 EAU91163.1 - 5.8e-07 29.3 1.6 1.7e-06 27.8 1.6 1.9 1 0 0 1 1 1 1 F-box-like Glyco_hydro_92 PF07971.12 EAU91164.2 - 2.7e-120 402.4 0.4 3.4e-120 402.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EAU91164.2 - 3.6e-48 164.5 0.0 8.3e-48 163.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain DUF3528 PF12045.8 EAU91164.2 - 0.08 13.6 0.5 0.7 10.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3528) GPI2 PF06432.11 EAU91169.2 - 8e-59 199.4 8.0 3.3e-49 167.8 3.2 2.3 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Oxidored_q3 PF00499.20 EAU91169.2 - 0.029 14.1 1.8 1.1 9.0 0.7 3.0 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TauE PF01925.19 EAU91169.2 - 0.042 13.5 3.7 0.46 10.1 3.5 2.6 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE DUF1345 PF07077.11 EAU91169.2 - 0.09 12.5 0.2 0.09 12.5 0.2 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1345) ILVD_EDD PF00920.21 EAU91170.2 - 6.7e-206 684.9 0.0 8.3e-206 684.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.28 EAU91171.2 - 8.1e-17 60.3 0.9 2.2e-05 24.1 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU91171.2 - 7.2e-16 57.0 1.4 0.00012 21.9 0.1 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EAU91171.2 - 1.4e-10 40.5 0.3 0.019 15.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU91171.2 - 3.3e-10 40.5 2.7 1.3e-07 32.1 0.1 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU91171.2 - 8.8e-09 35.5 5.1 0.011 16.5 0.0 5.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU91171.2 - 1.7e-07 30.7 0.1 0.5 10.5 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAU91171.2 - 2.5e-07 30.3 1.4 0.00067 19.3 0.1 3.9 2 1 2 4 4 4 2 TPR repeat TPR_17 PF13431.6 EAU91171.2 - 5.6e-07 29.5 0.2 0.14 12.6 0.0 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAU91171.2 - 3.2e-06 27.6 5.6 0.051 14.1 0.2 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU91171.2 - 1.1e-05 25.6 0.8 0.017 15.4 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAU91171.2 - 0.00058 20.3 0.3 3.3 8.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAU91171.2 - 0.00079 18.7 5.3 0.022 14.0 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAU91171.2 - 0.0051 16.9 0.2 0.71 10.1 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 EAU91171.2 - 0.02 14.3 0.6 0.041 13.3 0.0 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_10 PF13374.6 EAU91171.2 - 0.028 14.3 3.6 2.4 8.2 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EAU91171.2 - 0.084 13.2 0.3 4.7 7.6 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 EAU91174.2 - 7.4e-39 133.7 0.1 1.6e-27 96.5 0.1 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Pheromone PF08015.11 EAU91176.2 - 1.8e-05 25.6 0.3 0.0013 19.8 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone p450 PF00067.22 EAU91179.2 - 1.4e-62 212.0 0.0 6.9e-62 209.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 RPA43_OB PF17875.1 EAU91180.1 - 6.2e-32 110.8 0.1 6.2e-32 110.8 0.1 3.0 3 1 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EAU91180.1 - 2.9e-09 37.2 0.0 5.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 FAM176 PF14851.6 EAU91180.1 - 7 6.3 9.5 0.11 12.1 0.8 2.4 3 0 0 3 3 3 0 FAM176 family Pam16 PF03656.13 EAU91181.2 - 4e-14 52.7 0.0 9.1e-07 28.9 0.1 2.1 2 0 0 2 2 2 2 Pam16 DnaJ PF00226.31 EAU91181.2 - 0.084 13.0 0.2 0.1 12.7 0.2 1.2 1 0 0 1 1 1 0 DnaJ domain PALP PF00291.25 EAU91182.1 - 8.3e-73 245.3 0.4 9.5e-73 245.2 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.21 EAU91183.1 - 1.5e-77 258.9 0.0 1.8e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EAU91183.1 - 2.3e-15 56.8 0.1 3.2e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU91183.1 - 4e-13 49.3 0.0 4.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EAU91183.1 - 7.5e-12 45.1 1.6 1.5e-07 30.9 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EAU91183.1 - 1.2e-11 44.4 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAU91183.1 - 1.7e-09 37.4 0.0 2.2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU91183.1 - 0.0001 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EAU91183.1 - 0.015 14.6 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.14 EAU91183.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LRR_8 PF13855.6 EAU91184.1 - 7.7e-12 44.8 12.9 7.9e-08 32.0 1.9 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EAU91184.1 - 1.3e-11 44.5 14.6 4.5e-05 23.7 0.1 4.6 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EAU91184.1 - 0.043 13.3 0.1 0.17 11.4 0.1 1.9 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EAU91184.1 - 0.38 10.9 13.3 13 6.1 0.5 5.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 EAU91184.1 - 0.81 10.5 11.4 1.2e+02 3.8 0.0 5.7 4 1 1 5 5 5 0 Leucine Rich Repeat Aldo_ket_red PF00248.21 EAU91187.1 - 2.5e-46 158.2 0.0 8.9e-46 156.4 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Transposase_mut PF00872.18 EAU91187.1 - 0.074 11.9 0.3 0.13 11.1 0.1 1.4 2 0 0 2 2 2 0 Transposase, Mutator family Sigma70_r3 PF04539.16 EAU91187.1 - 0.12 12.4 0.1 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 region 3 E1-E2_ATPase PF00122.20 EAU91188.2 - 1.1e-47 161.9 0.4 1.1e-47 161.9 0.4 3.0 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EAU91188.2 - 8.8e-39 133.1 2.1 1.9e-38 132.0 2.1 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EAU91188.2 - 1.2e-19 71.4 0.2 8.5e-19 68.7 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EAU91188.2 - 3.3e-14 52.3 0.0 2.5e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EAU91188.2 - 1.3e-11 44.4 0.0 2.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EAU91188.2 - 0.00025 20.9 2.0 0.0022 17.8 1.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 EAU91188.2 - 0.00079 19.4 2.3 0.0015 18.5 0.0 2.6 3 0 0 3 3 3 1 Positive regulator of sigma(E), RseC/MucC RhoGEF PF00621.20 EAU91189.2 - 1.3e-36 126.5 0.0 2.7e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain Prominin PF05478.11 EAU91189.2 - 0.00016 19.8 0.2 0.00022 19.3 0.2 1.2 1 0 0 1 1 1 1 Prominin PSD4 PF07631.11 EAU91189.2 - 0.13 12.8 0.3 13 6.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) TPR_MLP1_2 PF07926.12 EAU91189.2 - 3 7.9 5.7 1 9.4 0.4 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FAD_binding_4 PF01565.23 EAU91190.2 - 3.6e-08 33.3 0.3 0.0017 18.1 0.2 3.8 3 1 0 3 3 3 2 FAD binding domain BBE PF08031.12 EAU91190.2 - 1e-07 31.9 0.1 2.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EAU91190.2 - 3.2e-05 23.5 0.0 4.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.14 EAU91190.2 - 0.2 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Ank_2 PF12796.7 EAU91192.1 - 1.6e-22 79.9 0.0 2.8e-13 50.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU91192.1 - 1.7e-13 49.4 0.2 5.5e-05 23.2 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EAU91192.1 - 3.4e-13 49.5 0.6 8.5e-06 26.0 0.1 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU91192.1 - 2.1e-11 44.1 1.8 0.0011 19.5 0.1 3.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EAU91192.1 - 2e-08 34.3 0.9 0.00057 20.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat GntP_permease PF02447.16 EAU91193.2 - 0.62 8.7 3.8 1.6 7.4 2.1 2.2 2 0 0 2 2 2 0 GntP family permease zf-CHY PF05495.12 EAU91194.2 - 3.6e-14 53.0 19.4 6.3e-14 52.2 19.4 1.4 1 0 0 1 1 1 1 CHY zinc finger Cys_rich_KTR PF14205.6 EAU91194.2 - 0.0018 18.1 6.6 0.33 10.8 2.7 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR zf-C2H2_6 PF13912.6 EAU91194.2 - 0.6 10.2 6.1 0.65 10.1 1.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.19 EAU91194.2 - 1.1 9.2 10.8 4.2 7.4 10.8 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 EAU91194.2 - 2.1 8.3 12.4 3.4 7.7 0.8 3.3 2 1 0 2 2 2 0 zinc-ribbon domain DpnI PF06044.12 EAU91194.2 - 4.3 6.9 7.6 1 9.0 3.3 1.8 1 1 1 2 2 2 0 Dam-replacing family Zn-ribbon_8 PF09723.10 EAU91194.2 - 5.5 7.2 16.1 0.087 13.0 4.7 2.7 1 1 2 3 3 3 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 EAU91194.2 - 5.6 7.0 10.5 2.6 8.1 0.7 2.9 2 1 1 3 3 3 0 SprT-like zinc ribbon domain C1_4 PF07975.12 EAU91194.2 - 8.2 6.7 14.1 4.2 7.7 5.1 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain DUF4379 PF14311.6 EAU91194.2 - 9.3 6.7 12.2 0.18 12.2 2.2 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain FCH PF00611.23 EAU91195.2 - 1.6e-14 53.9 0.1 4.4e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EAU91195.2 - 1.6e-10 40.4 0.1 2.8e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU91195.2 - 2.5e-08 33.6 0.1 4.7e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU91195.2 - 6.4e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Adaptin_binding PF10199.9 EAU91195.2 - 2.7 8.6 5.2 9 6.9 0.0 2.8 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Clat_adaptor_s PF01217.20 EAU91197.1 - 2.2e-15 56.8 0.0 4.3e-15 55.9 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.22 EAU91199.1 - 9.5e-31 105.4 3.9 1.9e-10 40.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAU91199.1 - 5.9e-06 25.9 0.0 0.037 13.6 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 EAU91199.1 - 8.6e-05 22.4 0.1 2.1 8.2 0.0 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF1866) RRM_3 PF08777.11 EAU91199.1 - 0.00034 20.6 0.2 0.7 10.0 0.2 2.7 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 EAU91199.1 - 0.00041 20.2 0.0 3.2 7.7 0.0 4.2 4 0 0 4 4 4 1 Occluded RNA-recognition motif NID PF07292.13 EAU91199.1 - 0.047 14.3 0.0 29 5.4 0.0 3.2 4 0 0 4 4 4 0 Nmi/IFP 35 domain (NID) RRM_7 PF16367.5 EAU91199.1 - 0.072 13.2 0.0 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif TA0956 PF11513.8 EAU91199.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 N2227 PF07942.12 EAU91201.1 - 3.3e-64 216.7 0.0 4.5e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EAU91201.1 - 0.042 14.6 0.0 0.13 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EAU91201.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Tcp11 PF05794.13 EAU91202.2 - 8.7e-11 41.6 0.2 1.1e-09 38.0 0.2 2.4 1 1 0 1 1 1 1 T-complex protein 11 Lyase_aromatic PF00221.19 EAU91203.2 - 6.2e-147 490.0 4.8 8.3e-147 489.6 4.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase eIF2_C PF09173.11 EAU91203.2 - 0.0003 21.0 0.1 0.26 11.6 0.0 2.7 2 0 0 2 2 2 2 Initiation factor eIF2 gamma, C terminal Cation_efflux PF01545.21 EAU91204.2 - 2.8e-46 157.8 2.0 3.7e-46 157.4 2.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EAU91204.2 - 2.5e-14 53.2 0.3 7.2e-14 51.7 0.1 1.9 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Fe-ADH PF00465.19 EAU91205.2 - 5.7e-68 229.4 0.0 7.1e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EAU91205.2 - 1.6e-17 64.1 0.0 2.5e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Flavin_Reduct PF01613.18 EAU91206.2 - 3.2e-16 59.7 0.1 4.7e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Amidohydro_1 PF01979.20 EAU91207.2 - 1.2e-35 123.4 0.0 1.5e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EAU91207.2 - 3.8e-15 56.3 0.0 1.1e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Aldo_ket_red PF00248.21 EAU91208.1 - 9e-70 235.2 0.1 1.1e-69 234.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AsnA PF03590.15 EAU91208.1 - 0.0038 17.0 0.2 0.0065 16.2 0.2 1.4 1 0 0 1 1 1 1 Aspartate-ammonia ligase Prefoldin_3 PF13758.6 EAU91208.1 - 0.15 12.1 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Aldo_ket_red PF00248.21 EAU91209.1 - 2.7e-66 223.7 0.2 3.1e-66 223.6 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AsnA PF03590.15 EAU91209.1 - 0.048 13.4 0.5 0.12 12.1 0.2 1.8 1 1 1 2 2 2 0 Aspartate-ammonia ligase zf-RING_2 PF13639.6 EAU91210.2 - 8e-12 45.3 8.3 1.5e-11 44.4 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EAU91210.2 - 2.1e-06 27.4 5.1 2.1e-06 27.4 5.1 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EAU91210.2 - 1.6e-05 24.7 7.6 2.7e-05 23.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAU91210.2 - 2.5e-05 24.2 1.7 4.6e-05 23.4 1.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EAU91210.2 - 0.0002 21.5 7.7 0.00062 20.0 7.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EAU91210.2 - 0.00074 19.4 5.6 0.0014 18.6 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 EAU91210.2 - 0.0015 18.7 3.5 0.0036 17.4 3.5 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.6 EAU91210.2 - 0.0035 17.1 6.0 0.0059 16.4 6.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EAU91210.2 - 0.0067 16.3 3.9 0.013 15.3 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU91210.2 - 0.052 13.6 7.7 0.085 12.9 3.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EAU91210.2 - 0.058 13.3 10.5 0.5 10.3 11.0 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EAU91210.2 - 0.11 12.6 5.3 0.2 11.8 5.3 1.4 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EAU91210.2 - 1.7 8.6 7.7 4.6 7.2 4.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Josephin PF02099.17 EAU91211.1 - 4.8e-50 169.8 0.1 2.4e-49 167.6 0.0 2.1 2 0 0 2 2 2 1 Josephin UIM PF02809.20 EAU91211.1 - 0.49 10.4 25.4 0.15 12.1 2.0 4.4 4 0 0 4 4 4 0 Ubiquitin interaction motif DUF572 PF04502.13 EAU91211.1 - 0.54 9.8 15.4 0.018 14.7 8.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) Atg14 PF10186.9 EAU91211.1 - 1 8.4 5.7 0.65 9.0 3.7 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG27 PF09451.10 EAU91213.2 - 4.2e-59 200.6 0.0 4.9e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EAU91213.2 - 6.9e-06 25.3 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Cauli_VI PF01693.16 EAU91214.1 - 2e-15 56.8 0.2 1.3e-07 31.8 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin DASH_Duo1 PF08651.10 EAU91217.2 - 9e-21 73.4 0.0 1.4e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 PhetRS_B1 PF18262.1 EAU91217.2 - 0.78 10.0 2.6 0.65 10.3 0.5 1.9 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Vfa1 PF08432.10 EAU91217.2 - 3.7 7.8 8.2 12 6.2 3.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DEAD PF00270.29 EAU91218.1 - 8.7e-40 136.3 0.0 3.3e-39 134.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU91218.1 - 3.5e-23 82.1 0.1 1.3e-22 80.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EAU91218.1 - 4e-21 75.0 2.9 2.6e-20 72.4 2.8 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain TGT PF01702.18 EAU91219.2 - 3.6e-129 430.9 0.0 4.1e-129 430.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase EMP70 PF02990.16 EAU91220.2 - 6.8e-196 651.9 0.2 9.2e-196 651.5 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TMEM40 PF15817.5 EAU91220.2 - 1.4 8.7 4.2 4.4 7.1 4.2 1.8 1 0 0 1 1 1 0 Transmembrane protein 40 family tRNA-synt_1b PF00579.25 EAU91221.1 - 9.2e-72 241.8 0.0 1.2e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EAU91221.1 - 0.00017 21.4 0.3 0.02 14.7 0.3 2.4 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Ribosom_S12_S23 PF00164.25 EAU91222.1 - 2.6e-49 165.6 0.9 3.2e-49 165.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transglut_core PF01841.19 EAU91224.1 - 3.4e-10 40.4 0.0 8.1e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily CTP_transf_1 PF01148.20 EAU91225.1 - 5.1e-73 246.1 19.6 6.9e-73 245.7 19.6 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family SEEEED PF14797.6 EAU91225.1 - 0.013 15.7 9.3 0.02 15.1 9.3 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex COX7C PF02935.16 EAU91225.1 - 0.061 13.6 0.2 0.061 13.6 0.2 3.6 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIIc eIF3_subunit PF08597.10 EAU91225.1 - 6.2 6.7 10.7 14 5.5 10.7 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFIIA PF03153.13 EAU91225.1 - 9.3 6.1 10.5 12 5.7 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Topoisom_I_N PF02919.15 EAU91226.2 - 1.2e-97 325.6 6.1 1.2e-97 325.6 6.1 3.2 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 EAU91226.2 - 7.4e-82 274.1 5.9 7.4e-82 274.1 5.9 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 EAU91226.2 - 1.2e-35 121.2 0.3 5.7e-35 119.1 0.3 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain HAD_2 PF13419.6 EAU91227.1 - 4.4e-07 30.1 0.0 7.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU91227.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like PALP PF00291.25 EAU91228.2 - 5.4e-78 262.4 0.2 7e-78 262.0 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EAU91228.2 - 4.9e-43 144.8 0.0 1e-24 86.1 0.0 2.5 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF3301 PF11743.8 EAU91228.2 - 0.1 12.3 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Vps8 PF12816.7 EAU91230.2 - 3.4e-68 229.1 0.0 6.9e-68 228.1 0.0 1.5 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EAU91230.2 - 5.6e-05 23.1 0.3 0.054 13.4 0.1 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS Herpes_UL16 PF03044.14 EAU91230.2 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus UL16/UL94 family ANAPC4_WD40 PF12894.7 EAU91230.2 - 0.019 15.3 0.0 0.22 11.9 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU91230.2 - 0.03 15.2 0.0 0.26 12.2 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Arc PF03869.14 EAU91230.2 - 0.047 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Arc-like DNA binding domain DUF3510 PF12022.8 EAU91231.2 - 3.7e-29 101.7 0.2 1.7e-28 99.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) COG2 PF06148.11 EAU91231.2 - 8.2e-28 97.1 3.4 8.2e-28 97.1 3.4 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 EAU91231.2 - 0.00038 19.2 1.1 0.0063 15.1 1.1 2.1 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Vps51 PF08700.11 EAU91231.2 - 0.00069 19.7 0.5 0.0033 17.5 0.3 2.4 1 1 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 EAU91231.2 - 0.014 14.7 1.0 0.024 13.9 1.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Allexi_40kDa PF05549.11 EAU91231.2 - 0.031 13.8 0.5 0.078 12.5 0.5 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spc7 PF08317.11 EAU91231.2 - 0.036 13.0 3.4 0.089 11.7 3.4 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 EAU91231.2 - 0.1 13.4 1.0 0.35 11.6 0.2 2.4 2 0 0 2 2 2 0 Occludin homology domain CHIP_TPR_N PF18391.1 EAU91231.2 - 0.18 12.6 5.2 0.19 12.5 2.4 2.6 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Hemerythrin PF01814.23 EAU91232.2 - 1.7e-15 57.8 8.1 2.3e-15 57.4 8.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF455 PF04305.14 EAU91232.2 - 0.053 13.1 2.0 0.065 12.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) LCE6A PF15858.5 EAU91233.2 - 0.27 12.0 2.4 0.47 11.2 0.7 2.2 2 0 0 2 2 2 0 Late cornified envelope protein 6A family Aminotran_5 PF00266.19 EAU91235.1 - 1e-29 103.6 0.0 3.6e-28 98.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Uso1_p115_head PF04869.14 EAU91236.2 - 1.4e-46 159.1 0.0 1.1e-45 156.2 0.0 2.5 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EAU91236.2 - 6.5e-15 55.6 17.0 1.1e-14 54.9 17.0 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 EAU91236.2 - 0.00032 20.3 11.1 0.00057 19.4 11.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 MIF4G_like_2 PF09090.11 EAU91236.2 - 0.035 13.6 3.9 0.063 12.8 3.9 1.4 1 0 0 1 1 1 0 MIF4G like Atx10homo_assoc PF09759.9 EAU91236.2 - 0.059 13.4 0.2 18 5.4 0.0 3.8 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF3818 PF12825.7 EAU91236.2 - 0.12 11.4 4.4 0.19 10.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) COMP PF11598.8 EAU91236.2 - 0.14 12.7 0.8 0.38 11.3 0.8 1.8 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Spc7 PF08317.11 EAU91236.2 - 0.21 10.4 9.3 0.31 9.9 9.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 EAU91236.2 - 0.22 11.9 13.8 0.41 11.0 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) OmpH PF03938.14 EAU91236.2 - 0.36 11.2 11.0 0.8 10.0 11.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlxA PF14282.6 EAU91236.2 - 0.43 10.6 13.9 1.1 9.3 13.9 1.7 1 0 0 1 1 1 0 FlxA-like protein RRP36 PF06102.12 EAU91236.2 - 0.97 9.4 9.9 1.7 8.6 9.9 1.3 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 MerR-DNA-bind PF09278.11 EAU91236.2 - 1.2 9.8 6.2 11 6.6 0.1 3.4 3 0 0 3 3 3 0 MerR, DNA binding Lectin_N PF03954.14 EAU91236.2 - 1.5 8.6 7.2 5.1 6.8 4.2 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Phage_GPO PF05929.11 EAU91236.2 - 1.8 8.1 7.9 2.8 7.5 7.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 EAU91236.2 - 2.6 7.3 6.9 3.9 6.7 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 EAU91236.2 - 6 6.0 5.7 11 5.2 5.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Cwf_Cwc_15 PF04889.12 EAU91236.2 - 8.8 6.0 16.7 13 5.5 16.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HAUS6_N PF14661.6 EAU91236.2 - 9.2 5.8 8.6 2.9 7.4 5.5 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Clathrin_lg_ch PF01086.17 EAU91237.1 - 4.8e-48 164.2 1.8 6.5e-48 163.8 1.8 1.2 1 0 0 1 1 1 1 Clathrin light chain Endonuc_Holl PF10107.9 EAU91237.1 - 2.6 7.9 7.7 3.9 7.3 7.7 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4407 PF14362.6 EAU91237.1 - 5.8 6.2 9.5 7.5 5.8 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PGP_phosphatase PF09419.10 EAU91238.1 - 2.6e-32 111.8 0.0 2.6e-19 69.4 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EAU91238.1 - 0.015 15.3 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_4 PF12146.8 EAU91239.1 - 1.2e-56 191.6 0.0 1.5e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU91239.1 - 1.9e-12 48.3 0.0 2.4e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU91239.1 - 5.3e-10 39.4 0.2 3.7e-08 33.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU91239.1 - 5.9e-05 22.6 0.0 0.039 13.4 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 EAU91239.1 - 0.0086 14.8 0.2 0.019 13.6 0.1 1.6 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EAU91239.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.25 EAU91239.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) DLH PF01738.18 EAU91239.1 - 0.02 14.5 0.0 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.14 EAU91239.1 - 0.021 14.1 0.1 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_2 PF02230.16 EAU91239.1 - 0.07 12.9 0.3 1.6 8.5 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 EAU91239.1 - 0.12 10.8 0.3 7.8 4.9 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase_phd PF10503.9 EAU91239.1 - 0.16 11.4 0.0 15 5.0 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase ABC_membrane PF00664.23 EAU91240.2 - 1.3e-49 169.4 0.5 1.9e-49 168.8 0.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EAU91240.2 - 8e-32 110.6 0.0 1.8e-31 109.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EAU91240.2 - 9.3e-05 22.0 0.0 0.005 16.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EAU91240.2 - 0.075 12.8 0.1 0.56 10.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EAU91240.2 - 0.085 13.1 0.3 0.43 10.9 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EAU91240.2 - 0.2 12.0 3.1 0.37 11.1 0.5 2.8 3 1 0 3 3 3 0 AAA ATPase domain DrrA_P4M PF14860.6 EAU91241.2 - 0.013 15.4 1.0 0.074 12.9 1.0 2.1 1 1 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF4795 PF16043.5 EAU91241.2 - 0.025 14.2 6.5 0.041 13.5 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Peptidase_S46 PF10459.9 EAU91241.2 - 0.041 12.5 2.6 0.048 12.3 2.6 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF445 PF04286.12 EAU91241.2 - 0.079 12.8 1.8 0.098 12.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3605 PF12239.8 EAU91241.2 - 0.11 12.8 0.7 0.24 11.7 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3605) PIN_8 PF18476.1 EAU91241.2 - 0.2 11.5 3.6 0.27 11.1 2.0 1.8 1 1 1 2 2 2 0 PIN like domain HlyD_2 PF12700.7 EAU91241.2 - 0.23 10.2 3.6 0.3 9.8 3.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein ARGLU PF15346.6 EAU91241.2 - 0.85 9.5 11.9 1.7 8.5 11.8 1.6 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Vir_act_alpha_C PF10400.9 EAU91241.2 - 4.1 8.1 8.5 12 6.7 0.0 3.2 3 1 0 3 3 3 0 Virulence activator alpha C-term QCR10 PF09796.9 EAU91242.1 - 1.2e-16 60.6 0.1 1.4e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Nop16 PF09420.10 EAU91243.2 - 2.7e-53 181.1 4.5 3.1e-53 180.9 4.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 EFTUD2 PF16004.5 EAU91243.2 - 0.021 15.4 2.3 0.12 13.0 2.3 2.2 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Rsa3 PF14615.6 EAU91243.2 - 0.071 12.7 0.2 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 Ribosome-assembly protein 3 NUDIX PF00293.28 EAU91244.1 - 1.2e-17 64.2 0.0 2.2e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 EAU91244.1 - 6.6e-12 46.0 0.0 1.9e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EAU91244.1 - 0.016 14.9 1.8 0.037 13.7 1.8 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain SnoaL_2 PF12680.7 EAU91245.1 - 5.3e-07 30.2 0.2 6.5e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EAU91245.1 - 2.7e-06 27.9 0.2 3.2e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_4 PF13577.6 EAU91245.1 - 0.06 13.5 0.1 0.1 12.7 0.1 1.3 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 EAU91246.1 - 6.9e-06 26.6 0.0 1e-05 26.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Peptidase_S24 PF00717.23 EAU91246.1 - 0.044 13.7 0.3 0.088 12.8 0.3 1.5 1 0 0 1 1 1 0 Peptidase S24-like SnoaL_2 PF12680.7 EAU91249.2 - 0.00013 22.6 0.0 0.00019 22.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EAU91249.2 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EAU91250.1 - 0.0059 17.2 0.0 0.0089 16.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EAU91250.1 - 0.044 13.6 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase HlyIII PF03006.20 EAU91250.1 - 0.21 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Haemolysin-III related Ring_hydroxyl_A PF00848.19 EAU91251.2 - 0.93 9.4 3.1 5.3 6.9 0.1 2.7 2 1 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) ubiquitin PF00240.23 EAU91252.2 - 2.3e-07 30.4 0.1 1.2e-06 28.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EAU91252.2 - 1.6e-06 28.4 0.1 7.7e-06 26.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain RAWUL PF16207.5 EAU91252.2 - 0.0039 17.8 0.0 0.0045 17.6 0.0 1.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 EAU91252.2 - 0.011 15.5 0.0 0.089 12.6 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 EAU91252.2 - 0.16 12.5 0.0 0.18 12.3 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Foie-gras_1 PF11817.8 EAU91254.1 - 1.5e-39 136.2 0.6 4.1e-37 128.2 0.1 3.0 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 EAU91254.1 - 1e-16 60.8 0.0 6.5e-12 45.0 0.0 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 EAU91254.1 - 0.0013 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 EAU91254.1 - 0.034 13.9 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_12 PF13424.6 EAU91254.1 - 0.066 13.5 0.2 0.066 13.5 0.2 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU91254.1 - 0.13 12.3 1.4 0.46 10.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU91254.1 - 0.57 10.4 6.0 0.29 11.3 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EAU91254.1 - 1.2 9.1 6.4 0.25 11.3 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat GST_N_2 PF13409.6 EAU91255.1 - 7.1e-19 67.9 0.1 2e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU91255.1 - 9.8e-19 67.6 0.0 1.9e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EAU91255.1 - 1.8e-10 41.0 0.3 3.3e-10 40.1 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU91255.1 - 1.4e-07 31.4 0.1 5.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EAU91255.1 - 0.00039 20.9 0.0 0.00061 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU91255.1 - 0.00051 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU91255.1 - 0.016 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IL23 PF16649.5 EAU91255.1 - 0.051 13.6 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Interleukin 23 subunit alpha Peptidase_M43 PF05572.13 EAU91256.1 - 1.7e-17 63.7 0.0 3.4e-17 62.8 0.0 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EAU91256.1 - 8.3e-07 29.6 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EAU91256.1 - 9.5e-07 29.2 0.1 1.4e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.8 EAU91256.1 - 0.003 17.2 1.1 0.0061 16.2 1.1 1.6 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.24 EAU91256.1 - 0.0063 16.4 0.3 0.0083 16.0 0.3 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 EAU91256.1 - 0.0091 15.0 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 EAU91256.1 - 0.0091 15.7 1.7 0.018 14.7 1.1 1.9 1 1 1 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EAU91256.1 - 0.039 13.2 2.2 0.065 12.4 0.2 2.2 3 0 0 3 3 3 0 Met-zincin Abhydrolase_3 PF07859.13 EAU91257.2 - 6.1e-38 130.8 0.0 7.8e-34 117.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU91257.2 - 2e-08 33.5 0.0 3.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EAU91257.2 - 0.0089 14.9 0.8 0.037 12.9 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family APH PF01636.23 EAU91258.1 - 1.5e-36 126.6 0.0 2e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAU91258.1 - 6.8e-06 25.8 0.0 0.0001 22.0 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 EAU91258.1 - 0.0074 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase HSP70 PF00012.20 EAU91259.1 - 7.6e-264 876.4 13.0 8.8e-264 876.2 13.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EAU91259.1 - 3.3e-13 49.2 6.2 2.6e-12 46.2 0.6 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 EAU91259.1 - 0.068 13.6 10.1 1.9 9.0 0.1 4.2 3 3 0 3 3 3 0 Cell division protein FtsA IMUP PF15761.5 EAU91259.1 - 0.81 10.4 9.6 0.21 12.3 1.9 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein F-box PF00646.33 EAU91260.2 - 6.5e-08 32.3 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU91260.2 - 0.00041 20.2 0.2 0.0009 19.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like Hexapep PF00132.24 EAU91261.1 - 1.4e-12 46.8 15.6 5.1e-08 32.3 2.1 4.6 4 1 1 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EAU91261.1 - 1.7e-06 27.6 12.5 0.0011 18.7 0.7 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EAU91261.1 - 4.9e-05 22.4 0.0 7.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase TMEM70 PF06979.12 EAU91262.1 - 2.1e-05 24.9 0.0 3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex FMN_dh PF01070.18 EAU91264.2 - 5.2e-120 400.6 0.1 6.3e-120 400.3 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EAU91264.2 - 1.6e-22 79.4 0.0 3.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EAU91264.2 - 4e-05 22.9 0.0 6.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EAU91264.2 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PEP_mutase PF13714.6 EAU91265.1 - 7.6e-42 143.4 3.0 9.3e-42 143.1 3.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EAU91265.1 - 6.8e-18 64.4 0.5 9.4e-18 64.0 0.5 1.1 1 0 0 1 1 1 1 Isocitrate lyase family F-box PF00646.33 EAU91266.2 - 0.00028 20.7 0.1 0.0012 18.7 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU91266.2 - 0.0012 18.7 0.1 0.0043 16.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like Cas_Cas4 PF01930.17 EAU91267.1 - 0.0047 17.0 0.2 0.021 15.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 EAU91267.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF1128 PF06569.11 EAU91267.1 - 0.043 13.8 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) DNA_photolyase PF00875.18 EAU91267.1 - 0.095 12.7 0.2 0.8 9.7 0.0 2.4 3 0 0 3 3 3 0 DNA photolyase DUF1778 PF08681.11 EAU91267.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) F-box-like PF12937.7 EAU91269.1 - 9.9e-06 25.4 0.3 9.9e-06 25.4 0.3 2.9 3 0 0 3 3 3 1 F-box-like DivIC PF04977.15 EAU91269.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Septum formation initiator Uds1 PF15456.6 EAU91269.1 - 0.15 12.3 3.0 0.29 11.3 3.0 1.4 1 0 0 1 1 1 0 Up-regulated During Septation RSN1_7TM PF02714.15 EAU91270.2 - 3.3e-69 233.3 22.1 3.3e-69 233.3 22.1 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EAU91270.2 - 4e-36 124.1 0.2 4e-36 124.1 0.2 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EAU91270.2 - 8.5e-36 123.8 0.0 1.9e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DNA_pol_phi PF04931.13 EAU91275.1 - 1.6 6.8 6.6 2 6.4 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi APS_kinase PF01583.20 EAU91278.1 - 5.3e-72 240.9 0.0 6.4e-72 240.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EAU91278.1 - 2.5e-06 27.7 0.0 5.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EAU91278.1 - 0.00013 22.5 0.0 0.00019 22.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EAU91278.1 - 0.0091 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 EAU91278.1 - 0.013 15.0 0.0 0.014 14.8 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 G-alpha PF00503.20 EAU91278.1 - 0.024 13.8 0.0 0.052 12.7 0.0 1.5 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 EAU91278.1 - 0.13 11.5 0.0 0.29 10.4 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EAU91278.1 - 0.15 12.6 0.0 0.18 12.3 0.0 1.3 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 EAU91278.1 - 0.15 11.9 0.2 0.35 10.7 0.2 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Pkinase PF00069.25 EAU91279.2 - 4.1e-65 219.8 0.0 5.3e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91279.2 - 2.9e-49 167.7 0.0 4e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU91279.2 - 0.0001 21.2 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EAU91279.2 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU91279.2 - 0.0022 18.0 0.0 0.79 9.6 0.0 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAU91279.2 - 0.0029 16.6 0.0 0.018 14.0 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EAU91279.2 - 0.0042 16.5 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EAU91279.2 - 0.0096 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Hexapep PF00132.24 EAU91280.1 - 4.3e-10 38.9 1.3 0.00032 20.3 1.9 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EAU91280.1 - 1.9e-07 31.6 0.0 3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EAU91280.1 - 3.5e-07 30.1 0.0 1.5e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase DUF4954 PF16314.5 EAU91280.1 - 0.011 13.9 0.4 0.019 13.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EAU91280.1 - 0.08 12.7 4.0 0.36 10.6 1.7 2.4 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase tRNA-synt_2c PF01411.19 EAU91282.2 - 6.2e-207 688.5 0.0 8e-207 688.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EAU91282.2 - 7.8e-17 61.1 0.3 1.7e-16 60.0 0.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EAU91282.2 - 1.5e-14 54.6 8.7 4e-14 53.2 8.7 1.8 1 0 0 1 1 1 1 DHHA1 domain CLASP_N PF12348.8 EAU91283.2 - 2.1e-18 66.8 0.0 3.2e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal DUF5305 PF17231.2 EAU91284.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Asp PF00026.23 EAU91285.2 - 5e-59 200.3 0.1 6.3e-59 200.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EAU91285.2 - 3.1e-13 50.3 2.7 1e-07 32.3 0.1 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EAU91285.2 - 0.095 13.3 0.0 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease PTPLA PF04387.14 EAU91286.1 - 2e-58 196.8 7.4 3.2e-58 196.1 7.4 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA NIF PF03031.18 EAU91287.2 - 3.4e-44 150.4 0.0 5e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EAU91287.2 - 0.037 14.4 0.0 0.053 13.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase bZIP_1 PF00170.21 EAU91288.2 - 8.9e-06 25.7 8.1 8.9e-06 25.7 8.1 3.2 2 1 1 3 3 3 1 bZIP transcription factor DDHD PF02862.17 EAU91288.2 - 0.01 16.0 5.0 0.022 14.9 1.0 2.1 2 0 0 2 2 2 0 DDHD domain LCD1 PF09798.9 EAU91288.2 - 0.017 13.7 2.9 0.03 12.9 2.9 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Presenilin PF01080.17 EAU91288.2 - 1.2 7.8 17.4 1.2 7.8 11.4 2.1 2 0 0 2 2 2 0 Presenilin Methyltransf_32 PF13679.6 EAU91288.2 - 5.4 7.0 11.2 2.6 8.0 5.6 2.3 2 1 0 2 2 2 0 Methyltransferase domain TPP1 PF10341.9 EAU91289.2 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Rab5ip PF07019.12 EAU91290.2 - 0.012 16.2 0.2 0.045 14.4 0.0 1.9 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Fib_alpha PF08702.10 EAU91290.2 - 0.35 11.0 23.8 0.026 14.7 7.2 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family AKNA PF12443.8 EAU91290.2 - 1.1 10.0 14.0 0.12 13.0 4.8 3.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor ATG16 PF08614.11 EAU91290.2 - 2.3 8.4 36.6 8.2 6.6 29.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) E2R135 PF11570.8 EAU91290.2 - 5.2 7.4 9.4 81 3.5 9.4 2.3 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 Borrelia_P83 PF05262.11 EAU91290.2 - 7.1 5.0 18.8 11 4.4 18.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Striatin PF08232.12 EAU91290.2 - 8.3 7.0 21.5 16 6.1 7.0 2.8 1 1 1 2 2 2 0 Striatin family NIF PF03031.18 EAU91291.2 - 1.6e-55 187.1 0.4 2.2e-55 186.7 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EAU91291.2 - 0.064 13.6 0.1 0.39 11.1 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HMMR_C PF15908.5 EAU91292.2 - 5.9e-08 33.1 4.7 5.9e-08 33.1 4.7 4.6 2 2 0 3 3 3 1 Hyaluronan mediated motility receptor C-terminal Tup_N PF08581.10 EAU91292.2 - 0.017 15.4 2.0 0.017 15.4 2.0 7.9 3 2 5 9 9 9 0 Tup N-terminal DASH_Dam1 PF08653.10 EAU91292.2 - 8.1 6.3 8.0 39 4.2 0.0 4.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 BTB PF00651.31 EAU91293.2 - 1.2e-11 44.8 0.0 0.00017 21.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain RhoGAP PF00620.27 EAU91294.2 - 6.8e-41 139.6 0.1 2.3e-40 137.9 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EAU91294.2 - 8.2e-13 48.4 30.0 4.6e-08 33.2 8.4 3.3 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 EAU91294.2 - 7.6e-07 28.9 6.8 7.6e-07 28.9 6.8 4.1 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) YabA PF06156.13 EAU91294.2 - 0.012 16.3 3.6 0.3 11.7 0.1 3.6 2 1 1 3 3 3 0 Initiation control protein YabA C1_2 PF03107.16 EAU91294.2 - 0.018 15.4 2.9 0.018 15.4 2.9 4.2 3 2 1 4 4 4 0 C1 domain Paired_CXXCH_1 PF09699.10 EAU91294.2 - 0.038 13.8 7.5 0.5 10.2 4.0 2.8 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) TPR_MLP1_2 PF07926.12 EAU91294.2 - 1.1 9.3 12.8 8.5 6.4 0.7 3.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein HALZ PF02183.18 EAU91294.2 - 1.7 8.9 4.0 26 5.2 0.8 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper RICH PF05062.12 EAU91294.2 - 2.1 8.7 4.1 3.6 8.0 0.9 2.7 2 0 0 2 2 2 0 RICH domain DUF5082 PF16888.5 EAU91294.2 - 4.1 7.7 5.6 27 5.0 0.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TMF_TATA_bd PF12325.8 EAU91294.2 - 5.2 7.3 11.8 0.23 11.7 1.6 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EAU91294.2 - 9.8 6.7 16.2 4.3 7.9 7.1 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region KTI12 PF08433.10 EAU91295.2 - 7.6e-82 274.8 0.0 9e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EAU91295.2 - 3e-10 40.4 0.0 5.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ELL PF10390.9 EAU91296.2 - 5.1e-10 39.3 0.6 5.1e-10 39.3 0.6 3.7 2 2 0 2 2 2 1 RNA polymerase II elongation factor ELL Helitron_like_N PF14214.6 EAU91301.2 - 4e-58 196.8 0.1 9.7e-58 195.5 0.0 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus DNA_primase_S PF01896.19 EAU91312.2 - 1.3e-50 171.9 0.1 1.7e-50 171.5 0.1 1.1 1 0 0 1 1 1 1 DNA primase small subunit GrpE PF01025.19 EAU91313.2 - 0.058 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 GrpE Adaptin_N PF01602.20 EAU91314.2 - 2.2e-23 82.6 1.1 1.5e-21 76.6 0.1 2.6 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.6 EAU91314.2 - 0.00034 20.9 3.8 0.061 13.7 0.5 3.9 3 1 0 3 3 3 2 HEAT repeats Profilin PF00235.19 EAU91314.2 - 0.0012 19.2 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 Profilin Cnd1 PF12717.7 EAU91314.2 - 0.0029 17.6 0.1 0.13 12.3 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAU91314.2 - 0.23 11.8 2.0 77 4.0 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 EAU91314.2 - 0.43 11.1 2.2 4.1 8.0 0.2 3.7 4 0 0 4 4 4 0 HEAT-like repeat RabGAP-TBC PF00566.18 EAU91315.1 - 1.4e-39 136.0 0.0 1.9e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBF PF01758.16 EAU91316.2 - 2e-51 174.5 11.1 2e-51 174.5 11.1 2.6 3 0 0 3 3 3 1 Sodium Bile acid symporter family TssO PF17561.2 EAU91316.2 - 0.36 10.9 2.2 0.78 9.8 2.2 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO bZIP_1 PF00170.21 EAU91318.1 - 6.7e-06 26.1 6.1 1.4e-05 25.1 6.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAU91318.1 - 0.0054 16.8 7.4 0.012 15.7 7.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.18 EAU91318.1 - 0.11 12.8 0.9 0.25 11.7 0.9 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family AA_permease PF00324.21 EAU91319.2 - 4e-51 174.1 15.4 5.2e-51 173.7 15.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAU91319.2 - 5.5e-12 45.2 15.4 7.2e-12 44.9 15.4 1.0 1 0 0 1 1 1 1 Amino acid permease IU_nuc_hydro PF01156.19 EAU91320.2 - 4.3e-39 134.9 0.0 5.3e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase WD40 PF00400.32 EAU91321.1 - 2.2e-45 151.7 23.2 6.1e-09 36.4 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU91321.1 - 7.9e-11 42.1 0.8 0.078 13.3 0.0 4.9 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EAU91321.1 - 3.6e-05 22.6 7.4 0.0055 15.4 0.2 4.4 3 1 2 5 5 5 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 EAU91321.1 - 0.00015 21.0 0.0 0.1 11.7 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) PD40 PF07676.12 EAU91321.1 - 0.002 18.0 0.7 6.6 6.8 0.0 4.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EAU91321.1 - 0.0051 15.4 0.2 0.39 9.2 0.2 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EAU91321.1 - 0.21 10.9 0.0 13 5.0 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain FtsX_ECD PF18075.1 EAU91322.2 - 0.16 12.6 0.0 0.33 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsX extracellular domain Got1 PF04178.12 EAU91323.2 - 3.5e-19 69.3 13.8 5e-19 68.8 13.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Pkinase PF00069.25 EAU91327.2 - 5.1e-33 114.6 0.0 2.7e-31 108.9 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91327.2 - 2.6e-17 63.0 0.0 4.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU91327.2 - 0.069 12.4 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EAU91327.2 - 0.14 12.0 0.0 0.43 10.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cyclin PF08613.11 EAU91328.2 - 2.9e-19 70.0 0.4 1.3e-18 67.9 0.2 1.9 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 EAU91328.2 - 0.0038 17.0 0.1 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.14 EAU91329.1 - 6.9e-24 83.5 0.1 1.1e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EAU91329.1 - 1e-17 64.4 0.5 1.9e-17 63.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HGAL PF15666.5 EAU91330.2 - 0.083 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Germinal center-associated lymphoma Thioredoxin_5 PF13743.6 EAU91334.1 - 0.04 13.6 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin DUF966 PF06136.13 EAU91334.1 - 3.5 7.2 16.5 1.8 8.2 14.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF966) Palm_thioest PF02089.15 EAU91335.2 - 1.7e-83 280.2 0.0 1.9e-83 280.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EAU91335.2 - 0.0095 15.6 0.1 0.039 13.6 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Nucleos_tra2_C PF07662.13 EAU91338.1 - 4.7e-69 232.4 7.6 4.7e-69 232.4 7.6 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EAU91338.1 - 1.6e-20 73.5 7.0 1.6e-20 73.5 7.0 3.7 4 1 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EAU91338.1 - 0.0052 17.0 6.9 0.0052 17.0 6.9 3.3 2 1 0 2 2 2 1 Nucleoside recognition WD40 PF00400.32 EAU91339.1 - 2.8e-11 43.8 3.7 2.4e-05 25.0 0.0 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 EAU91339.1 - 0.079 11.6 0.0 7.2 5.1 0.0 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Apq12 PF12716.7 EAU91341.2 - 0.023 14.6 3.3 0.058 13.4 3.3 1.7 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis MPC PF03650.13 EAU91342.1 - 3.4e-41 139.8 0.1 3.7e-41 139.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF3421 PF11901.8 EAU91343.1 - 1.3e-31 109.0 0.2 2e-24 85.8 0.0 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) DUF4106 PF13388.6 EAU91343.1 - 6.9 5.8 10.0 10 5.2 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Tetraspanin PF00335.20 EAU91344.1 - 0.0047 16.7 10.2 0.0047 16.7 10.2 1.5 1 1 0 1 1 1 1 Tetraspanin family HlyIII PF03006.20 EAU91344.1 - 0.067 12.9 1.9 4.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Haemolysin-III related XPG_I PF00867.18 EAU91346.2 - 9.7e-19 67.5 0.0 1.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 EAU91346.2 - 1.1e-15 58.4 9.7 7.4e-15 55.7 0.1 4.3 3 2 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EAU91346.2 - 0.04 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain Peptidase_M22 PF00814.25 EAU91347.1 - 3.9e-75 253.0 0.0 4.6e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family HbrB PF08539.11 EAU91348.2 - 2e-55 187.4 0.0 3.8e-55 186.4 0.0 1.5 1 0 0 1 1 1 1 HbrB-like Amidohydro_3 PF07969.11 EAU91349.2 - 8.4e-75 253.0 0.0 1.4e-73 249.0 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EAU91349.2 - 9e-16 58.1 0.0 6.6e-15 55.3 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family DUF1616 PF07760.11 EAU91349.2 - 0.032 13.6 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) zf-rbx1 PF12678.7 EAU91350.2 - 2.4e-13 50.1 4.8 4.6e-13 49.2 4.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EAU91350.2 - 1.3e-09 38.2 7.6 4.5e-09 36.5 7.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EAU91350.2 - 6.2e-07 29.2 4.5 1.4e-06 28.0 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EAU91350.2 - 3.2e-06 27.1 0.6 7.8e-06 25.9 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EAU91350.2 - 7e-06 26.0 3.0 7e-06 26.0 3.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EAU91350.2 - 8.3e-06 25.5 4.1 8.3e-06 25.5 4.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EAU91350.2 - 0.00041 20.2 4.1 0.001 19.0 4.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EAU91350.2 - 0.00064 19.3 0.7 0.0016 18.0 0.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EAU91350.2 - 0.00065 19.5 3.3 0.00065 19.5 3.3 2.0 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EAU91350.2 - 0.0011 18.8 1.2 0.0011 18.8 1.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EAU91350.2 - 0.0068 16.1 0.6 0.0068 16.1 0.6 2.5 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EAU91350.2 - 0.013 15.6 1.7 0.034 14.3 1.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EAU91350.2 - 0.017 15.3 0.8 0.042 14.0 0.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EAU91350.2 - 0.34 11.2 2.4 0.68 10.3 2.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EAU91350.2 - 0.73 9.7 3.3 0.44 10.4 1.0 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YqeY PF09424.10 EAU91351.1 - 9.2e-26 90.6 2.0 1.1e-25 90.4 2.0 1.1 1 0 0 1 1 1 1 Yqey-like protein EntA_Immun PF08951.10 EAU91351.1 - 0.031 14.6 0.1 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Enterocin A Immunity PriCT_1 PF08708.11 EAU91351.1 - 0.098 12.4 2.3 1.6 8.5 0.8 2.9 2 1 0 2 2 2 0 Primase C terminal 1 (PriCT-1) NAD_kinase PF01513.21 EAU91353.1 - 9.9e-74 248.2 0.0 2.1e-73 247.1 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase NOA36 PF06524.12 EAU91353.1 - 1.8 7.8 4.4 3.4 6.9 4.4 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EAU91353.1 - 5.7 5.1 10.3 9 4.5 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.22 EAU91356.2 - 7.9e-23 80.1 0.0 9.8e-23 79.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU91356.2 - 0.0013 18.8 0.0 0.0018 18.4 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EAU91356.2 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.19 EAU91357.1 - 6.8e-16 58.4 0.2 6.8e-16 58.4 0.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU91357.1 - 9e-06 26.2 0.1 9e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 HMG-box domain ALS_ss_C PF10369.9 EAU91358.2 - 3.1e-19 68.9 0.1 3.9e-18 65.4 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EAU91358.2 - 3.5e-13 49.1 0.1 6.2e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EAU91358.2 - 4.7e-07 29.5 0.0 9.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain Dynamitin PF04912.14 EAU91359.2 - 7.7e-62 209.8 4.9 1.2e-61 209.3 4.9 1.2 1 0 0 1 1 1 1 Dynamitin DUF3584 PF12128.8 EAU91359.2 - 0.0004 18.1 1.6 0.00084 17.0 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) AIP3 PF03915.13 EAU91359.2 - 0.0011 18.1 0.6 0.0018 17.4 0.6 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 TMF_TATA_bd PF12325.8 EAU91359.2 - 0.0018 18.5 3.3 0.17 12.1 0.9 2.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding YPEB PF14620.6 EAU91359.2 - 0.013 14.8 0.4 0.038 13.3 0.4 1.7 1 0 0 1 1 1 0 YpeB sporulation Baculo_PEP_C PF04513.12 EAU91359.2 - 0.017 15.2 7.7 0.1 12.7 1.3 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 EAU91359.2 - 0.022 14.8 2.3 0.022 14.8 2.3 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein SesA PF17107.5 EAU91359.2 - 0.025 14.8 2.4 0.1 12.8 0.4 2.5 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Syntaxin-6_N PF09177.11 EAU91359.2 - 0.026 15.1 0.4 0.026 15.1 0.4 3.2 3 2 0 3 3 3 0 Syntaxin 6, N-terminal CENP-H PF05837.12 EAU91359.2 - 0.047 14.1 5.4 0.092 13.2 1.1 2.8 3 0 0 3 3 2 0 Centromere protein H (CENP-H) Spc24 PF08286.11 EAU91359.2 - 0.07 13.4 3.1 0.44 10.8 0.7 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 MPS2 PF17060.5 EAU91359.2 - 0.076 12.3 1.6 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 TolA_bind_tri PF16331.5 EAU91359.2 - 0.11 12.5 7.3 2.2 8.4 0.4 4.0 3 1 0 3 3 3 0 TolA binding protein trimerisation Laminin_II PF06009.12 EAU91359.2 - 0.17 11.9 5.5 0.1 12.6 1.9 2.4 3 1 0 3 3 2 0 Laminin Domain II Spc7 PF08317.11 EAU91359.2 - 0.25 10.2 6.1 0.069 12.0 1.8 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein TACC_C PF05010.14 EAU91359.2 - 0.37 10.6 3.7 0.29 10.9 0.7 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal WXG100 PF06013.12 EAU91359.2 - 0.39 11.0 2.8 0.36 11.1 0.3 2.3 2 0 0 2 2 1 0 Proteins of 100 residues with WXG COG2 PF06148.11 EAU91359.2 - 0.96 9.5 7.2 0.37 10.9 0.8 3.1 4 0 0 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Cnn_1N PF07989.11 EAU91359.2 - 1.1 9.5 5.5 1.8 8.8 0.5 2.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 EAU91359.2 - 1.1 9.7 8.9 7.4 7.1 3.1 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region CorA PF01544.18 EAU91359.2 - 4 6.7 9.5 0.43 9.9 0.7 2.6 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.22 EAU91359.2 - 4.7 7.5 8.0 0.62 10.3 1.4 2.9 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 EAU91359.2 - 7.9 6.8 8.5 8.4 6.7 0.4 3.8 4 0 0 4 4 4 0 ABC transporter C-terminal domain Snapin_Pallidin PF14712.6 EAU91359.2 - 9.1 6.8 11.3 0.63 10.5 1.5 3.7 3 2 1 4 4 4 0 Snapin/Pallidin STE3 PF02076.15 EAU91360.1 - 9.2e-109 363.1 16.0 1.2e-108 362.8 16.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mid2 PF04478.12 EAU91360.1 - 6.3 6.6 5.3 2.7 7.8 0.2 2.7 1 1 1 3 3 3 0 Mid2 like cell wall stress sensor Mannosyl_trans2 PF04188.13 EAU91361.1 - 7.7e-52 177.1 17.4 9.6e-52 176.8 17.4 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Pex24p PF06398.11 EAU91362.1 - 5.1e-35 121.1 11.9 4.7e-34 117.9 11.9 2.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Gemini_AL2 PF01440.16 EAU91363.1 - 3.6 8.0 11.6 0.098 13.1 4.5 2.0 2 0 0 2 2 2 0 Geminivirus AL2 protein DUF1631 PF07793.11 EAU91363.1 - 6.1 5.1 6.5 8 4.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF3684 PF12449.8 EAU91364.2 - 0 1276.1 0.3 0 1275.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EAU91364.2 - 0.026 14.3 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.15 EAU91365.2 - 1.2e-247 822.7 0.0 1.6e-247 822.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 EAU91365.2 - 1.7e-12 47.7 0.1 4.9e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EAU91365.2 - 6.4e-10 39.3 8.4 6.4e-10 39.3 8.4 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EAU91365.2 - 0.0049 16.4 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EAU91365.2 - 0.22 11.3 0.0 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 LETM1 PF07766.13 EAU91367.2 - 3.1e-21 75.9 1.7 2.6e-11 43.4 0.2 2.1 1 1 1 2 2 2 2 LETM1-like protein Med27 PF11571.8 EAU91368.2 - 8.1e-10 38.9 0.1 1.8e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 DOCK_N PF16172.5 EAU91370.2 - 1.4e-114 382.9 0.0 2.2e-114 382.3 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 EAU91370.2 - 1.4e-71 241.8 0.6 4.7e-71 240.0 0.6 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EAU91370.2 - 4.9e-48 163.5 0.0 2.6e-47 161.1 0.0 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF4349 PF14257.6 EAU91371.2 - 0.0092 15.5 4.0 0.17 11.3 1.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4349) Spectrin PF00435.21 EAU91371.2 - 0.011 16.2 1.2 0.029 14.9 1.2 1.7 1 0 0 1 1 1 0 Spectrin repeat IFT57 PF10498.9 EAU91371.2 - 0.025 13.6 0.6 0.039 12.9 0.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GAS PF13851.6 EAU91371.2 - 0.035 13.5 1.9 0.065 12.6 1.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 EAU91371.2 - 0.049 14.1 0.2 0.61 10.6 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Swi5 PF07061.11 EAU91371.2 - 0.07 13.2 4.3 0.48 10.5 0.0 3.1 2 1 0 2 2 2 0 Swi5 DUF4763 PF15960.5 EAU91371.2 - 0.092 12.0 2.6 0.2 10.9 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 EAU91371.2 - 0.12 11.2 2.7 0.21 10.4 2.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein FemAB PF02388.16 EAU91371.2 - 0.23 10.3 1.5 0.34 9.7 1.5 1.2 1 0 0 1 1 1 0 FemAB family DUF2802 PF10975.8 EAU91371.2 - 0.65 10.2 11.0 0.97 9.6 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2802) BLOC1_2 PF10046.9 EAU91371.2 - 0.96 9.8 3.5 4.6 7.6 1.3 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 EAU91371.2 - 0.99 7.9 2.6 1.6 7.3 2.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF2203 PF09969.9 EAU91371.2 - 1.2 9.9 2.8 3.1 8.5 2.0 2.0 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2203) DivIC PF04977.15 EAU91371.2 - 3.2 7.6 9.4 5.7 6.8 3.2 3.2 2 1 1 3 3 3 0 Septum formation initiator FUSC PF04632.12 EAU91371.2 - 5.1 5.5 9.5 1 7.8 5.1 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Snapin_Pallidin PF14712.6 EAU91371.2 - 5.3 7.5 7.3 20 5.7 3.8 3.1 2 1 1 3 3 3 0 Snapin/Pallidin APG5 PF04106.12 EAU91372.1 - 1.8e-66 224.0 0.0 2.2e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1115 PF06544.12 EAU91372.1 - 0.1 12.7 0.3 14 5.8 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1115) Dfp1_Him1_M PF08630.10 EAU91373.2 - 5.8e-34 117.0 0.4 2.3e-33 115.1 0.0 2.3 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EAU91373.2 - 1.1e-19 70.3 0.3 2.3e-19 69.2 0.3 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 EAU91373.2 - 8.3e-05 22.9 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EAU91373.2 - 0.00099 19.0 0.0 0.0037 17.2 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EAU91373.2 - 0.061 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain SAM_decarbox PF01536.16 EAU91374.1 - 4.6e-121 404.1 0.0 5.3e-121 404.0 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1279 PF06916.13 EAU91375.1 - 2.5e-19 69.6 0.0 3.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Rax2 PF12768.7 EAU91377.1 - 3.3e-45 154.2 1.9 6.5e-43 146.7 0.7 3.8 3 0 0 3 3 3 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 EAU91377.1 - 1.7e-10 40.3 0.0 3.5e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU91377.1 - 5.2e-09 35.8 0.3 1.1e-08 34.8 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.6 EAU91377.1 - 6.6e-06 26.2 1.5 2.3 8.6 0.1 5.8 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.15 EAU91377.1 - 5e-05 23.1 0.3 0.18 11.9 0.1 4.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 EAU91377.1 - 6.4e-05 22.4 0.4 2.6 7.7 0.0 4.7 4 0 0 4 4 4 2 Kelch motif DUF5122 PF17164.4 EAU91377.1 - 3 8.2 19.4 57 4.1 0.0 8.5 8 1 0 8 8 8 0 Domain of unknown function (DUF5122) beta-propeller zf-C2H2_2 PF12756.7 EAU91378.1 - 3.8e-37 126.7 7.3 9.7e-31 106.1 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EAU91378.1 - 3.1e-11 43.3 3.2 1.3e-10 41.3 3.2 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EAU91378.1 - 2.6e-08 33.9 16.6 1.4e-07 31.6 3.5 3.8 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 EAU91378.1 - 0.015 15.4 1.2 0.015 15.4 1.2 2.8 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_4 PF13894.6 EAU91378.1 - 0.039 14.8 16.3 0.044 14.6 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU91378.1 - 0.057 13.9 1.1 0.057 13.9 1.1 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF3449 PF11931.8 EAU91378.1 - 0.058 13.2 0.0 0.058 13.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) DPCD PF14913.6 EAU91378.1 - 0.06 12.7 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 DPCD protein family zf-BED PF02892.15 EAU91378.1 - 0.13 12.3 9.8 0.36 10.9 1.5 3.0 3 0 0 3 3 3 0 BED zinc finger TEX19 PF15553.6 EAU91378.1 - 0.14 12.1 0.9 0.3 11.0 0.9 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF3597 PF12200.8 EAU91378.1 - 0.47 11.0 2.0 0.98 10.0 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Rpr2 PF04032.16 EAU91378.1 - 1.4 9.3 4.8 0.86 9.9 1.2 2.3 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-UBP PF02148.19 EAU91378.1 - 2.6 8.4 6.0 4.8 7.6 0.1 3.1 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein Tho1_MOS11_C PF18592.1 EAU91379.1 - 5.7e-06 26.0 1.6 0.038 13.8 1.3 3.0 2 1 0 2 2 2 2 Tho1/MOS11 C-terminal domain HeH PF12949.7 EAU91379.1 - 3.2e-05 23.5 0.4 5.5e-05 22.8 0.4 1.3 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 EAU91379.1 - 0.0032 17.2 0.5 0.63 9.9 0.1 2.7 3 0 0 3 3 3 2 SAP domain Armet PF10208.9 EAU91379.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Rho_N PF07498.12 EAU91379.1 - 0.097 12.6 0.2 0.57 10.2 0.2 2.1 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Vinculin PF01044.19 EAU91379.1 - 0.26 9.5 6.6 0.35 9.0 6.6 1.1 1 0 0 1 1 1 0 Vinculin family CDC45 PF02724.14 EAU91379.1 - 6.1 5.0 8.9 7.2 4.8 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CBFB_NFYA PF02045.15 EAU91380.1 - 5.9e-27 94.1 7.1 5.9e-27 94.1 7.1 2.1 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PRIMA1 PF16101.5 EAU91380.1 - 0.22 11.6 11.5 0.45 10.6 11.5 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Phage_int_SAM_1 PF02899.17 EAU91389.2 - 0.012 15.8 0.2 1.2 9.5 0.0 3.2 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain RRM_2 PF04059.12 EAU91390.2 - 9.6e-34 115.5 0.6 1.7e-33 114.7 0.6 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EAU91390.2 - 2.1e-06 27.4 0.5 0.023 14.5 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EAU91390.2 - 0.0012 19.0 0.2 0.024 14.8 0.1 2.4 2 0 0 2 2 2 1 BRCA1-associated protein 2 DUF4520 PF15016.6 EAU91390.2 - 0.066 13.3 0.2 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) Abhydrolase_3 PF07859.13 EAU91391.2 - 3.5e-23 82.6 0.0 1.1e-22 81.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU91391.2 - 1e-08 34.5 0.0 2.7e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase StbA PF06406.11 EAU91391.2 - 0.21 10.8 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 StbA protein MCM PF00493.23 EAU91392.2 - 1.2e-99 332.0 0.0 1.7e-99 331.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAU91392.2 - 2e-38 131.1 0.0 3.5e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EAU91392.2 - 3.7e-36 124.7 27.8 6.7e-36 123.9 25.6 2.4 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EAU91392.2 - 2.6e-25 88.7 0.7 9.9e-25 86.8 0.7 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAU91392.2 - 8e-13 48.9 0.0 2.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAU91392.2 - 1.3e-07 31.2 0.0 3.8e-06 26.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAU91392.2 - 9.2e-06 25.7 0.0 3.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAU91392.2 - 0.00069 19.5 0.1 0.013 15.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SelR PF01641.18 EAU91392.2 - 0.0017 18.4 0.1 0.26 11.4 0.1 2.4 2 0 0 2 2 2 1 SelR domain Sigma54_activat PF00158.26 EAU91392.2 - 0.0039 16.9 0.1 0.03 14.0 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain HHH_2 PF12826.7 EAU91392.2 - 0.017 15.2 0.0 8 6.6 0.0 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif Yippee-Mis18 PF03226.14 EAU91392.2 - 0.04 14.1 0.1 0.094 12.9 0.1 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Sorting_nexin PF03700.13 EAU91392.2 - 1.1 9.8 12.3 1.8 9.1 10.7 2.3 1 1 0 1 1 1 0 Sorting nexin, N-terminal domain CHCH PF06747.13 EAU91393.2 - 2.1e-06 27.7 6.0 3.4e-06 27.0 6.0 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EAU91393.2 - 0.00067 20.0 3.5 0.0011 19.3 3.5 1.3 1 0 0 1 1 1 1 GCK domain Feld-I_B PF09252.10 EAU91393.2 - 0.011 15.6 0.2 0.019 14.9 0.2 1.3 1 0 0 1 1 1 0 Allergen Fel d I-B chain OmpH PF03938.14 EAU91394.1 - 2.5 8.5 7.0 4.3 7.7 7.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sec7 PF01369.20 EAU91395.2 - 3.9e-38 131.0 0.0 5.6e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PC4 PF02229.16 EAU91397.1 - 9.9e-24 82.7 0.2 2e-23 81.7 0.2 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF4122 PF13498.6 EAU91397.1 - 0.011 15.4 0.0 0.024 14.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4122) Edc3_linker PF16598.5 EAU91397.1 - 0.061 14.0 7.0 0.088 13.5 7.0 1.2 1 0 0 1 1 1 0 Linker region of enhancer of mRNA-decapping protein 3 Presenilin PF01080.17 EAU91397.1 - 0.45 9.2 7.4 0.43 9.3 7.4 1.0 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 EAU91397.1 - 0.65 8.5 19.9 0.79 8.2 19.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 EAU91397.1 - 1.3 7.8 8.3 1.3 7.8 8.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MRI PF15325.6 EAU91397.1 - 2.5 9.2 15.3 3.5 8.8 14.6 1.6 1 1 0 1 1 1 0 Modulator of retrovirus infection SLC12 PF03522.15 EAU91397.1 - 2.8 6.9 7.1 3.4 6.6 7.1 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 EAU91397.1 - 3.2 5.8 8.2 3.4 5.7 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 EAU91398.2 - 6.5e-102 341.3 0.0 6.5e-102 341.3 0.0 7.6 7 3 1 8 8 8 2 Domain of Unknown Function (DUF913) HECT PF00632.25 EAU91398.2 - 3.4e-92 309.2 0.0 5.9e-92 308.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 EAU91398.2 - 1.7e-85 287.6 0.1 1.7e-85 287.6 0.1 6.4 6 1 1 7 7 7 1 Domain of Unknown Function (DUF908) UBM PF14377.6 EAU91398.2 - 6.4e-30 101.7 20.4 2.1e-11 42.8 1.2 4.4 3 1 1 4 4 4 3 Ubiquitin binding region Arm PF00514.23 EAU91398.2 - 0.021 14.8 0.5 8 6.7 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat UBA PF00627.31 EAU91398.2 - 0.055 13.4 0.8 0.18 11.7 0.8 1.9 1 0 0 1 1 1 0 UBA/TS-N domain Mo25 PF08569.11 EAU91398.2 - 0.1 12.0 0.1 0.28 10.5 0.1 1.7 1 0 0 1 1 1 0 Mo25-like ADH_zinc_N PF00107.26 EAU91399.2 - 3.9e-30 104.5 0.4 5.9e-30 103.9 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU91399.2 - 6.1e-12 46.7 0.0 1e-11 46.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU91399.2 - 2.3e-05 24.3 0.0 0.00011 22.1 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EAU91399.2 - 0.0073 15.8 2.0 0.011 15.2 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase AlaDh_PNT_C PF01262.21 EAU91399.2 - 0.02 14.2 0.6 0.028 13.7 0.6 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AMP-binding PF00501.28 EAU91401.2 - 2.2e-91 306.6 0.0 2.7e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU91401.2 - 5.7e-13 49.6 0.2 1.3e-12 48.4 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RMI1_N PF08585.12 EAU91401.2 - 0.033 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 RecQ mediated genome instability protein RNA_pol_A_bac PF01000.26 EAU91402.2 - 1.1e-28 99.8 0.0 1.9e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAU91402.2 - 1.6e-12 46.7 0.1 3.2e-12 45.7 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 EAU91402.2 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain MS_channel PF00924.18 EAU91403.1 - 1.7e-24 86.6 0.3 3.6e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EAU91403.1 - 0.015 14.8 0.1 0.035 13.7 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EAU91403.1 - 0.066 13.2 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain Syntaxin PF00804.25 EAU91404.2 - 3.1e-06 27.0 0.5 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 2 Syntaxin SNARE PF05739.19 EAU91404.2 - 0.093 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 SNARE domain Syntaxin_2 PF14523.6 EAU91404.2 - 0.11 12.9 2.3 3.2 8.2 0.4 2.3 2 0 0 2 2 2 0 Syntaxin-like protein HAUS-augmin3 PF14932.6 EAU91404.2 - 0.29 10.7 4.1 1.4 8.4 0.3 2.6 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Fe_hyd_lg_C PF02906.14 EAU91406.1 - 9.7e-65 218.6 0.0 8.1e-64 215.6 0.0 2.0 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Polysacc_lyase PF14099.6 EAU91407.2 - 0.15 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase Aa_trans PF01490.18 EAU91408.2 - 1.7e-77 260.9 24.3 1.9e-77 260.7 24.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EAU91408.2 - 9.2e-06 24.9 3.5 9.2e-06 24.9 3.5 2.6 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Polysacc_synt_C PF14667.6 EAU91408.2 - 0.00033 20.7 2.3 0.00033 20.7 2.3 2.8 4 1 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF2574 PF10836.8 EAU91408.2 - 0.11 12.4 0.8 2.4 8.1 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2574) DUF962 PF06127.11 EAU91408.2 - 0.44 10.6 2.3 0.83 9.8 0.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Ferrochelatase PF00762.19 EAU91411.1 - 1.3e-103 346.4 0.0 1.5e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase UNC-79 PF14776.6 EAU91411.1 - 0.0056 15.5 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 CbiX PF01903.17 EAU91411.1 - 0.0059 16.9 0.0 0.7 10.2 0.0 3.0 3 0 0 3 3 3 1 CbiX WD40 PF00400.32 EAU91412.1 - 5e-25 87.3 11.3 2.7e-07 31.2 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU91412.1 - 7.2e-08 32.6 0.1 0.41 11.0 0.0 4.5 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAU91412.1 - 0.0015 18.0 0.0 0.079 12.3 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain DUF5046 PF16465.5 EAU91412.1 - 0.0057 16.1 0.2 0.028 13.9 0.1 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) PQQ PF01011.21 EAU91412.1 - 0.013 15.4 2.8 7.6 6.7 0.0 3.8 5 0 0 5 5 5 0 PQQ enzyme repeat Nup160 PF11715.8 EAU91412.1 - 0.014 14.1 0.9 0.84 8.2 0.1 3.2 2 1 0 4 4 4 0 Nucleoporin Nup120/160 UPF0154 PF03672.13 EAU91413.1 - 0.05 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Velvet PF11754.8 EAU91414.2 - 2.9e-41 142.1 0.0 3.7e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Ten1_2 PF15490.6 EAU91415.1 - 0.0059 16.3 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit SPX PF03105.19 EAU91417.2 - 5.2 6.9 19.7 8.8 6.1 0.0 2.4 2 0 0 2 2 2 0 SPX domain Ribosomal_S7 PF00177.21 EAU91418.1 - 9.1e-36 122.7 1.6 1.1e-35 122.5 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-C4_ClpX PF06689.13 EAU91420.1 - 0.042 13.7 0.6 0.042 13.7 0.6 1.9 2 0 0 2 2 2 0 ClpX C4-type zinc finger Gelsolin PF00626.22 EAU91421.2 - 0.0044 16.9 0.1 0.043 13.7 0.0 2.5 2 0 0 2 2 2 1 Gelsolin repeat Nse4_C PF08743.10 EAU91422.2 - 2.6e-27 94.9 0.2 1.3e-26 92.6 0.0 2.1 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EAU91422.2 - 4.3e-18 65.2 0.4 7.7e-18 64.3 0.4 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE PBP_dimer PF03717.15 EAU91422.2 - 0.063 13.6 0.1 0.095 13.0 0.1 1.3 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain SNF2_N PF00176.23 EAU91423.2 - 3.6e-65 220.0 0.0 5.3e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EAU91423.2 - 4.1e-19 68.3 0.1 9e-19 67.2 0.1 1.5 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 EAU91423.2 - 8.1e-10 39.4 0.0 2.1e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ResIII PF04851.15 EAU91423.2 - 1.8e-09 37.9 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAU91423.2 - 2.4e-07 31.1 0.0 0.0014 19.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EAU91423.2 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase WW PF00397.26 EAU91423.2 - 0.11 12.7 0.9 0.25 11.5 0.9 1.7 1 0 0 1 1 1 0 WW domain Acetyltransf_3 PF13302.7 EAU91424.2 - 3.7e-15 56.8 0.0 4.7e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU91424.2 - 2e-05 24.8 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EAU91424.2 - 0.0098 15.6 0.0 0.056 13.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ARPC4 PF05856.12 EAU91425.2 - 2.6e-81 271.1 5.4 2.9e-81 271.0 5.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) GPS2_interact PF15784.5 EAU91425.2 - 0.14 12.6 2.3 12 6.4 0.1 2.3 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain FKBP_C PF00254.28 EAU91426.1 - 8.7e-34 115.7 0.1 2e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EAU91426.1 - 2.1e-20 73.2 0.5 1.9e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Nucleoplasmin-like domain RNA_polI_A34 PF08208.11 EAU91426.1 - 3.3 7.7 29.3 1 9.4 24.2 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 MCM_bind PF09739.9 EAU91426.1 - 5.2 5.4 7.1 8.9 4.6 7.1 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor p450 PF00067.22 EAU91427.2 - 7.3e-60 203.0 0.0 1e-59 202.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WASH_WAHD PF11945.8 EAU91427.2 - 0.2 11.1 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex adh_short_C2 PF13561.6 EAU91428.1 - 5.3e-55 186.5 4.4 6.8e-55 186.2 4.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU91428.1 - 1.6e-41 141.9 3.6 2.3e-41 141.4 3.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU91428.1 - 1e-10 41.8 1.8 3.3e-10 40.2 1.8 1.7 1 1 0 1 1 1 1 KR domain ThiF PF00899.21 EAU91428.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 ThiF family Methyltransf_25 PF13649.6 EAU91428.1 - 0.11 13.2 0.0 0.58 10.9 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain E1-E2_ATPase PF00122.20 EAU91429.2 - 3.9e-33 114.5 0.1 3.9e-33 114.5 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase P5-ATPase PF12409.8 EAU91429.2 - 2.7e-24 85.6 0.0 5.7e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 EAU91429.2 - 8.5e-19 68.7 0.0 5.7e-09 36.6 0.0 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EAU91429.2 - 6.5e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EAU91429.2 - 0.00075 19.3 6.6 0.0021 17.8 6.6 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EAU91429.2 - 0.042 13.5 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EAU91429.2 - 0.052 13.3 0.1 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sel1 PF08238.12 EAU91431.2 - 2.8e-26 91.3 38.9 2.4e-07 31.2 1.5 10.0 9 2 0 9 9 9 7 Sel1 repeat TPR_16 PF13432.6 EAU91431.2 - 0.0063 17.1 0.3 0.0063 17.1 0.3 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAU91431.2 - 0.017 15.0 5.5 0.11 12.4 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU91431.2 - 0.094 12.9 0.1 0.094 12.9 0.1 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU91431.2 - 0.31 12.0 0.0 0.31 12.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EAU91431.2 - 0.69 10.7 13.1 17 6.3 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat SWIB PF02201.18 EAU91432.1 - 9.8e-30 102.3 0.2 9.8e-30 102.3 0.2 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 EAU91432.1 - 0.0076 16.2 0.2 0.1 12.5 0.1 2.6 2 1 0 2 2 2 1 DEK C terminal domain GREB1 PF15782.5 EAU91432.1 - 0.076 10.1 2.6 0.084 10.0 2.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNA_pol_Rpc82 PF05645.13 EAU91432.1 - 0.66 9.7 8.3 0.047 13.4 2.0 1.9 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 Presenilin PF01080.17 EAU91432.1 - 4.1 6.1 6.3 5.7 5.6 6.3 1.2 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 EAU91432.1 - 5.3 6.9 16.4 7.2 6.4 16.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Aldo_ket_red PF00248.21 EAU91434.2 - 4.4e-73 246.1 0.0 4.9e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAF PF03822.14 EAU91434.2 - 0.12 12.6 0.0 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 NAF domain FGAR-AT_linker PF18072.1 EAU91434.2 - 0.12 12.9 0.1 33 5.1 0.0 3.4 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain TIG PF01833.24 EAU91435.2 - 1.5e-11 44.2 0.0 5.4e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 EAU91435.2 - 2e-10 41.1 0.0 3.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU91435.2 - 8.8e-10 38.7 0.1 2.7e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU91435.2 - 1.2e-08 35.3 0.2 4.5e-08 33.5 0.2 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU91435.2 - 1.9e-08 33.9 0.1 0.0053 17.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EAU91435.2 - 2.4e-07 30.9 0.1 0.0019 18.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG_plexin PF17960.1 EAU91435.2 - 0.005 16.8 0.3 0.35 10.9 0.0 3.3 3 0 0 3 3 3 1 TIG domain NUP50 PF08911.11 EAU91436.1 - 2e-15 57.2 1.1 2e-15 57.2 1.1 8.4 8 2 0 8 8 8 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 EAU91436.1 - 1.5e-10 41.4 0.4 2.5e-10 40.7 0.4 1.3 1 0 0 1 1 1 1 RanBP1 domain Vfa1 PF08432.10 EAU91437.1 - 0.68 10.2 8.3 3.6 7.9 5.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 NinG PF05766.12 EAU91437.1 - 1.9 8.4 9.4 3 7.7 9.4 1.2 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF3915 PF13054.6 EAU91437.1 - 4.5 7.3 6.3 8.4 6.4 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) RraA-like PF03737.15 EAU91438.2 - 3.1e-34 118.3 0.0 4.3e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA VanZ PF04892.12 EAU91442.2 - 0.00024 21.7 3.0 0.00039 21.1 3.0 1.3 1 0 0 1 1 1 1 VanZ like family DUF1168 PF06658.12 EAU91442.2 - 0.088 12.6 0.8 0.18 11.6 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) Amidohydro_1 PF01979.20 EAU91444.1 - 4.4e-15 55.8 0.0 2.2e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EAU91444.1 - 6.1e-11 42.5 6.8 2.6e-08 33.8 0.0 4.3 4 1 1 5 5 5 2 Amidohydrolase family Med1 PF10744.9 EAU91444.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 XisI PF08869.11 EAU91444.1 - 0.18 12.1 0.0 0.39 11.1 0.0 1.4 1 0 0 1 1 1 0 XisI protein DUF2678 PF10856.8 EAU91445.2 - 0.87 9.5 6.1 2.9 7.8 6.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) MnhB PF04039.13 EAU91445.2 - 2.2 8.6 8.0 0.64 10.3 2.1 2.7 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter AFG1_ATPase PF03969.16 EAU91446.2 - 5.6e-49 166.9 0.0 3.3e-48 164.4 0.0 1.9 1 1 0 1 1 1 1 AFG1-like ATPase AAA_29 PF13555.6 EAU91446.2 - 4.8e-06 26.2 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU91446.2 - 8.2e-06 26.3 0.0 2.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EAU91446.2 - 0.0021 18.4 0.0 0.0049 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAU91446.2 - 0.0057 16.9 0.0 0.034 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EAU91446.2 - 0.0081 16.3 0.1 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EAU91446.2 - 0.028 14.1 0.0 6.2 6.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 EAU91446.2 - 0.17 12.3 0.0 1.1 9.7 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) HSP20 PF00011.21 EAU91448.2 - 0.00063 19.9 0.0 0.0051 16.9 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PI3K_1B_p101 PF10486.9 EAU91448.2 - 2.6 5.7 3.8 3.4 5.3 3.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PKK PF12474.8 EAU91449.2 - 1.1 9.4 9.5 3 8.0 9.5 1.7 1 0 0 1 1 1 0 Polo kinase kinase 2OG-FeII_Oxy_2 PF13532.6 EAU91450.2 - 3.6e-19 69.7 0.0 1.9e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ATP-synt_DE_N PF02823.16 EAU91451.1 - 4.8e-18 64.8 0.1 7e-18 64.3 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HypD PF01924.16 EAU91451.1 - 0.12 11.4 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family GCS PF03074.16 EAU91452.2 - 1.3e-175 584.1 0.0 1.6e-175 583.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 EAU91452.2 - 0.0022 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) APG6 PF04111.12 EAU91453.2 - 3.5e-73 245.4 0.0 5.4e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EAU91453.2 - 1.6e-25 90.1 22.4 1.6e-25 90.1 22.4 1.6 2 0 0 2 2 2 1 Apg6 coiled-coil region Macoilin PF09726.9 EAU91453.2 - 1.7 7.1 8.7 2.5 6.5 8.7 1.3 1 0 0 1 1 1 0 Macoilin family Peptidase_C14 PF00656.22 EAU91454.1 - 2.1e-19 70.4 0.0 3.9e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Dak1_2 PF13684.6 EAU91454.1 - 0.054 12.6 0.2 0.88 8.6 0.1 2.1 2 0 0 2 2 2 0 Dihydroxyacetone kinase family DEC-1_N PF04625.13 EAU91454.1 - 0.07 12.1 1.0 0.11 11.5 0.3 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region HicA_toxin PF07927.12 EAU91457.1 - 6.1e-11 42.2 0.0 1.8e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 HicA toxin of bacterial toxin-antitoxin, DNA_pol_phi PF04931.13 EAU91457.1 - 0.021 13.0 15.2 0.33 9.0 12.5 3.1 3 0 0 3 3 3 0 DNA polymerase phi NST1 PF13945.6 EAU91457.1 - 2.6 8.1 8.9 6.2 6.9 8.9 1.7 1 0 0 1 1 1 0 Salt tolerance down-regulator CE2_N PF17996.1 EAU91458.2 - 0.00061 19.8 0.2 0.052 13.5 0.0 2.7 3 1 0 3 3 3 1 Carbohydrate esterase 2 N-terminal SKG6 PF08693.10 EAU91458.2 - 0.0042 16.4 0.3 0.0085 15.5 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 EAU91458.2 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 EAU91458.2 - 0.12 12.2 0.3 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor VSP PF03302.13 EAU91458.2 - 0.2 10.5 0.8 0.29 10.0 0.8 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM171 PF15471.6 EAU91458.2 - 1.1 8.2 6.1 2.1 7.3 6.1 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Ank_4 PF13637.6 EAU91460.2 - 0.007 16.9 1.5 1.8 9.2 0.0 4.5 4 1 3 7 7 7 3 Ankyrin repeats (many copies) Glyco_transf_49 PF13896.6 EAU91462.2 - 1.1e-62 212.4 5.0 2.9e-51 174.8 0.6 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF1769 PF08588.10 EAU91462.2 - 0.089 13.0 0.0 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) BcrAD_BadFG PF01869.20 EAU91463.1 - 5.8e-21 75.2 0.0 8.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EAU91463.1 - 0.11 11.9 0.1 5.9 6.3 0.0 2.2 2 0 0 2 2 2 0 ROK family Cornichon PF03311.14 EAU91464.2 - 6.9e-53 178.1 10.2 8e-53 177.9 10.2 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 EAU91465.2 - 2.7e-52 176.2 9.9 3.1e-52 176.0 9.9 1.0 1 0 0 1 1 1 1 Cornichon protein RRM_1 PF00076.22 EAU91466.2 - 0.00053 19.8 0.0 0.00097 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 EAU91466.2 - 0.044 14.0 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding AMP-binding PF00501.28 EAU91467.1 - 6.4e-91 305.0 0.0 8.4e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU91467.1 - 1.7e-12 48.1 1.3 9.5e-12 45.7 0.3 2.6 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.28 EAU91469.2 - 9.3e-08 32.8 0.1 1.9e-07 31.8 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EAU91469.2 - 0.052 12.9 0.0 0.21 10.9 0.0 1.8 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Scs3p PF10261.9 EAU91470.1 - 1.1e-45 156.1 0.1 2.9e-37 128.5 0.0 2.1 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM ARL6IP6 PF15062.6 EAU91470.1 - 2.7 8.2 6.3 1.2 9.3 0.5 2.7 2 1 1 3 3 3 0 Haemopoietic lineage transmembrane helix ALAD PF00490.21 EAU91471.1 - 1.5e-120 402.2 0.0 1.8e-120 401.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.25 EAU91472.2 - 6.5e-41 140.4 0.0 9.5e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91472.2 - 5e-29 101.4 0.0 8.9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU91472.2 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Homeodomain PF00046.29 EAU91473.2 - 4.1e-18 65.0 3.1 6.9e-18 64.3 3.1 1.4 1 0 0 1 1 1 1 Homeodomain Herpes_UL25 PF01499.16 EAU91473.2 - 0.54 8.7 2.6 0.77 8.2 2.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Homeobox_KN PF05920.11 EAU91473.2 - 8.7 6.3 6.8 1.7 8.6 0.5 3.0 3 0 0 3 3 3 0 Homeobox KN domain pP_pnuc_2 PF18166.1 EAU91474.2 - 0.12 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease PIN_8 PF18476.1 EAU91474.2 - 0.63 9.9 4.9 0.33 10.8 2.0 1.9 2 0 0 2 2 2 0 PIN like domain cwf18 PF08315.12 EAU91474.2 - 1.7 9.3 6.9 2.1 9.0 1.4 2.5 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor FlaG PF03646.15 EAU91474.2 - 1.8 8.8 7.7 0.65 10.2 0.5 2.8 2 1 1 3 3 3 0 FlaG protein YlqD PF11068.8 EAU91474.2 - 4.9 7.5 17.7 0.17 12.2 1.5 2.8 2 1 1 3 3 3 0 YlqD protein BRCT_2 PF16589.5 EAU91475.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain NAD_kinase PF01513.21 EAU91476.2 - 1.6e-58 198.2 0.0 2.2e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EAU91476.2 - 0.021 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MJ1316 PF04457.12 EAU91477.1 - 0.069 13.9 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 MJ1316 RNA cyclic group end recognition domain XPG_I_2 PF12813.7 EAU91478.2 - 0.00055 19.5 0.0 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 XPG domain containing BSD PF03909.17 EAU91479.2 - 2.6e-12 46.5 2.0 6.2e-12 45.3 2.0 1.6 1 0 0 1 1 1 1 BSD domain LEDGF PF11467.8 EAU91479.2 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) EF-G-binding_N PF07299.11 EAU91479.2 - 0.075 13.6 0.0 0.23 12.0 0.0 1.8 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal CENP-B_dimeris PF09026.10 EAU91479.2 - 0.34 11.3 7.7 0.76 10.2 6.4 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Importin_rep_4 PF18808.1 EAU91479.2 - 2.4 8.5 4.8 7.4 6.9 4.8 1.8 1 0 0 1 1 1 0 Importin repeat CPSase_sm_chain PF00988.22 EAU91480.1 - 1.6e-44 150.8 0.0 2.5e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EAU91480.1 - 7.7e-37 126.9 0.0 1.1e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EAU91480.1 - 2.1e-08 34.2 0.4 6.7e-07 29.3 0.4 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EAU91480.1 - 0.00074 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family NADH_B2 PF14813.6 EAU91482.1 - 0.00063 19.5 0.2 0.00064 19.5 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SNARE_assoc PF09335.11 EAU91482.1 - 0.022 15.2 0.0 0.022 15.2 0.0 1.1 1 0 0 1 1 1 0 SNARE associated Golgi protein Metallophos PF00149.28 EAU91483.1 - 2.7e-19 70.5 1.9 3.6e-19 70.1 1.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU91483.1 - 0.01 16.1 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Shisa PF13908.6 EAU91483.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glycogen_syn PF05693.13 EAU91484.1 - 0 1112.5 0.0 0 1112.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 EAU91484.1 - 1.9e-07 31.1 0.1 5.1e-07 29.6 0.1 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EAU91484.1 - 1.3e-06 28.0 0.0 0.0003 20.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EAU91484.1 - 1.9e-06 28.3 0.0 0.0024 18.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAU91484.1 - 4.5e-05 23.5 0.4 9.7e-05 22.4 0.3 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EAU91484.1 - 7.1e-05 23.3 0.0 0.00017 22.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF92 PF01940.16 EAU91485.2 - 3.6e-55 187.0 10.2 4.6e-55 186.6 10.2 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 KH_1 PF00013.29 EAU91486.2 - 1.4e-80 265.1 30.7 3e-13 49.4 0.3 14.0 13 1 0 13 13 13 9 KH domain KH_2 PF07650.17 EAU91486.2 - 3.8e-09 36.3 17.9 0.2 11.5 0.2 7.0 6 2 1 7 7 7 4 KH domain SLS PF14611.6 EAU91486.2 - 7.9e-06 25.9 18.5 0.35 10.7 0.0 6.6 6 2 1 7 7 7 4 Mitochondrial inner-membrane-bound regulator DUF4974 PF16344.5 EAU91486.2 - 7.8e-05 22.6 0.2 0.026 14.5 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4974) KH_5 PF13184.6 EAU91486.2 - 0.0033 17.5 6.3 1.7 8.8 0.1 4.7 4 0 0 4 4 4 2 NusA-like KH domain KH_4 PF13083.6 EAU91486.2 - 0.018 14.9 14.8 1.5 8.7 0.1 6.9 10 0 0 10 10 10 0 KH domain MOEP19 PF16005.5 EAU91486.2 - 0.063 13.3 0.0 1.2 9.2 0.0 3.1 3 0 0 3 3 3 0 KH-like RNA-binding domain Usp PF00582.26 EAU91486.2 - 1.5 9.3 11.6 3.2 8.2 0.0 4.6 5 0 0 5 5 5 0 Universal stress protein family RRM_1 PF00076.22 EAU91487.2 - 8.1e-11 41.6 0.0 3.3e-07 30.0 0.0 3.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 EAU91487.2 - 7.2e-09 35.5 0.2 1.6e-08 34.4 0.2 1.6 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 EAU91487.2 - 0.0039 18.0 0.0 0.0088 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 EAU91487.2 - 0.17 12.0 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif NARP1 PF12569.8 EAU91487.2 - 6.5 5.5 9.3 1.4 7.8 0.2 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 PPP5 PF08321.12 EAU91488.1 - 1.4e-29 102.3 0.0 2.3e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 EAU91488.1 - 4e-26 92.8 0.1 6.5e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EAU91488.1 - 1.7e-13 49.7 11.3 6.8e-08 32.0 0.4 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAU91488.1 - 4.9e-10 39.1 3.0 0.0014 18.9 0.2 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU91488.1 - 9.8e-08 31.6 3.4 0.11 12.2 0.1 3.6 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.17 EAU91488.1 - 1.2e-07 31.2 11.0 0.0013 18.6 0.3 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAU91488.1 - 1.7e-05 24.8 0.2 0.0038 17.4 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAU91488.1 - 9.2e-05 22.9 2.7 0.22 12.0 1.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU91488.1 - 0.00021 21.8 1.5 0.66 11.0 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU91488.1 - 0.00026 21.6 2.0 0.028 15.0 0.9 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU91488.1 - 0.0026 17.8 3.5 0.0065 16.6 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EAU91488.1 - 0.045 12.9 0.3 4.6 6.4 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Orthopox_F14 PF06076.12 EAU91488.1 - 0.069 13.4 0.2 0.83 10.0 0.1 2.2 2 0 0 2 2 2 0 Orthopoxvirus F14 protein TPR_6 PF13174.6 EAU91488.1 - 0.12 13.0 0.8 1 10.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SLT PF01464.20 EAU91489.2 - 1.6e-08 34.2 0.1 5.8e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Transglycosylase SLT domain MSA-2c PF12238.8 EAU91489.2 - 0.094 12.7 6.3 0.16 11.9 6.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c DEC-1_N PF04625.13 EAU91489.2 - 1.2 8.1 7.6 1.7 7.6 7.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Cyclin PF08613.11 EAU91491.2 - 0.00075 19.9 0.1 0.0066 16.8 0.0 2.4 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EAU91491.2 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Zn_clus PF00172.18 EAU91493.2 - 6.9e-08 32.5 8.3 1.4e-07 31.5 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EAU91494.2 - 7.4e-67 225.5 0.0 8.8e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91494.2 - 1.1e-42 146.1 0.0 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU91494.2 - 0.00031 19.6 0.0 0.00043 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAU91494.2 - 0.004 16.5 0.0 0.018 14.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EAU91494.2 - 0.04 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Acetyltransf_1 PF00583.25 EAU91495.1 - 8.6e-14 51.8 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAU91495.1 - 5.8e-08 33.1 0.0 9.4e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EAU91495.1 - 1.8e-07 31.1 0.0 2.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EAU91495.1 - 1e-06 29.0 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EAU91495.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EAU91495.1 - 0.0028 18.3 0.0 0.0034 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU91495.1 - 0.031 14.2 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein dNK PF01712.19 EAU91495.1 - 0.033 14.0 0.4 0.092 12.6 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase DNA_ligase_A_M PF01068.21 EAU91496.2 - 2.6e-40 138.2 0.0 1.4e-37 129.3 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EAU91496.2 - 7.8e-36 124.0 0.0 6.7e-35 121.0 0.0 2.2 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EAU91496.2 - 8e-17 61.7 0.0 2e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pyrid_oxidase_2 PF13883.6 EAU91497.1 - 5e-16 59.1 0.1 5.4e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BolA PF01722.18 EAU91499.2 - 3.5e-30 104.1 0.3 4.2e-30 103.8 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein zf-C2H2 PF00096.26 EAU91500.2 - 2.3e-13 49.8 5.3 9.3e-07 29.0 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU91500.2 - 1e-08 35.2 8.7 0.00015 22.0 0.1 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU91500.2 - 1.3e-05 25.6 5.1 0.00071 20.2 1.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU91500.2 - 0.00045 20.4 1.1 0.0011 19.2 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EAU91500.2 - 0.0027 18.1 0.0 0.0097 16.3 0.0 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EAU91500.2 - 0.0089 16.4 0.9 0.023 15.1 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EAU91500.2 - 0.012 15.4 3.1 0.26 11.2 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EAU91500.2 - 0.048 13.7 4.8 0.15 12.1 1.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EAU91500.2 - 0.15 12.2 1.0 3.9 7.7 0.5 2.5 1 1 1 2 2 2 0 Zinc ribbon domain Pkinase PF00069.25 EAU91501.2 - 5.2e-34 117.8 0.3 6.7e-32 110.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91501.2 - 5e-10 39.1 0.0 7.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EAU91501.2 - 0.0052 15.8 0.2 0.008 15.2 0.2 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EAU91501.2 - 0.02 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EAU91501.2 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Homeodomain PF00046.29 EAU91502.2 - 7.4e-16 57.8 4.7 1.3e-15 57.0 4.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EAU91502.2 - 0.00014 21.6 0.2 0.00037 20.3 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Glyco_hydro_14 PF01373.17 EAU91502.2 - 0.028 13.4 0.1 0.041 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 YdaS_antitoxin PF15943.5 EAU91502.2 - 0.19 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Glyco_hydro_61 PF03443.14 EAU91503.2 - 1.3e-38 133.0 0.0 1.6e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ABC_tran PF00005.27 EAU91504.2 - 3.9e-48 163.5 0.0 2.3e-27 96.2 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EAU91504.2 - 2.2e-14 54.0 0.0 0.00027 20.9 0.0 4.2 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU91504.2 - 9.6e-14 51.3 0.0 3.4e-05 23.4 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EAU91504.2 - 5.4e-11 42.2 0.1 1.1e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EAU91504.2 - 3.8e-09 37.4 0.0 0.00014 22.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain HEAT PF02985.22 EAU91504.2 - 4.4e-07 29.6 5.5 0.63 10.5 0.1 4.9 5 0 0 5 5 4 3 HEAT repeat AAA_29 PF13555.6 EAU91504.2 - 7.4e-06 25.6 1.2 0.1 12.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU91504.2 - 1.1e-05 25.9 3.0 2.5 8.5 0.0 4.9 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EAU91504.2 - 1.9e-05 25.0 0.3 0.54 10.5 0.0 4.1 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EAU91504.2 - 1.9e-05 24.7 0.1 0.083 13.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU91504.2 - 6e-05 23.0 0.1 0.041 13.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase HEAT_2 PF13646.6 EAU91504.2 - 8e-05 23.0 3.7 0.13 12.7 0.2 3.8 3 0 0 3 3 3 1 HEAT repeats 4HB PF17947.1 EAU91504.2 - 0.00023 21.2 0.0 0.00072 19.6 0.0 1.8 1 0 0 1 1 1 1 Four helical bundle domain HEAT_EZ PF13513.6 EAU91504.2 - 0.00025 21.4 3.3 0.51 10.9 0.1 3.5 4 0 0 4 4 2 2 HEAT-like repeat DUF87 PF01935.17 EAU91504.2 - 0.00075 19.7 0.2 0.93 9.5 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 EAU91504.2 - 0.0013 18.9 0.1 1.3 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAU91504.2 - 0.0015 18.8 0.0 0.8 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU91504.2 - 0.0018 18.0 0.0 1.3 8.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain Tudor-knot PF11717.8 EAU91504.2 - 0.0019 18.0 0.2 0.0043 16.9 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain NACHT PF05729.12 EAU91504.2 - 0.0023 17.9 0.5 0.65 9.9 0.1 3.7 3 1 0 3 3 3 1 NACHT domain AAA_18 PF13238.6 EAU91504.2 - 0.003 18.1 0.0 1.9 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EAU91504.2 - 0.0062 16.3 0.4 3 7.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 EAU91504.2 - 0.0064 15.5 0.7 1.7 7.5 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EAU91504.2 - 0.0077 16.6 0.1 5.4 7.4 0.1 2.8 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.6 EAU91504.2 - 0.011 14.5 0.0 0.88 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.20 EAU91504.2 - 0.014 14.0 0.6 5 5.6 0.1 2.9 1 1 1 2 2 2 0 Adaptin N terminal region AAA_27 PF13514.6 EAU91504.2 - 0.016 14.8 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain IFRD PF05004.13 EAU91504.2 - 0.024 13.8 0.2 0.27 10.3 0.1 2.2 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Roc PF08477.13 EAU91504.2 - 0.026 14.8 0.0 5.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Cnd1 PF12717.7 EAU91504.2 - 0.038 14.0 0.1 6.5 6.8 0.0 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EAU91504.2 - 0.039 13.5 0.0 5.1 6.6 0.0 2.6 2 0 0 2 2 2 0 CLASP N terminal AAA_14 PF13173.6 EAU91504.2 - 0.044 13.8 0.0 5.8 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EAU91504.2 - 0.044 12.9 0.2 8.7 5.4 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 EAU91504.2 - 0.054 13.3 0.6 11 5.8 0.4 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 EAU91504.2 - 0.1 13.0 0.1 4.4 7.7 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 EAU91504.2 - 0.11 12.4 0.1 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 EAU91504.2 - 0.12 11.9 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Arf PF00025.21 EAU91504.2 - 0.13 11.7 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 EAU91504.2 - 0.13 12.3 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 EAU91504.2 - 0.16 11.8 0.2 42 3.9 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 EAU91504.2 - 0.25 11.0 1.3 7.7 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EAU91504.2 - 0.25 10.6 0.6 6.3 6.0 0.1 2.7 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EAU91504.2 - 0.26 10.9 0.8 27 4.3 0.4 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Acyltransferase PF01553.21 EAU91505.1 - 1.1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase pPIWI_RE_Z PF18155.1 EAU91505.1 - 0.24 11.3 1.1 0.61 9.9 0.1 2.1 3 0 0 3 3 3 0 pPIWI RE three-gene island domain Z NUC173 PF08161.12 EAU91507.2 - 2.1e-59 200.6 0.4 8.3e-58 195.4 0.0 2.7 3 0 0 3 3 3 1 NUC173 domain Adaptin_N PF01602.20 EAU91507.2 - 0.0057 15.3 0.8 2.7 6.5 0.1 2.8 3 0 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 EAU91507.2 - 0.033 14.4 0.1 1.6 9.2 0.1 3.2 2 0 0 2 2 2 0 HEAT repeat NLE PF08154.12 EAU91507.2 - 0.064 13.8 0.2 4 8.1 0.0 2.7 2 0 0 2 2 2 0 NLE (NUC135) domain MMS19_C PF12460.8 EAU91507.2 - 6.6 5.7 12.2 1.1 8.3 0.5 3.6 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal PAC2 PF09754.9 EAU91508.1 - 7.8e-26 91.4 0.1 1.3e-25 90.7 0.1 1.3 1 1 0 1 1 1 1 PAC2 family Peptidase_C12 PF01088.21 EAU91509.1 - 2.1e-56 191.0 0.0 2.5e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ETF PF01012.21 EAU91510.1 - 6.1e-35 120.8 2.4 1.2e-34 119.8 2.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EAU91510.1 - 1.1e-31 108.7 0.4 2.3e-31 107.7 0.4 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain PGM_PMM_II PF02879.16 EAU91510.1 - 0.11 13.2 0.0 2.7 8.7 0.0 2.7 3 1 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II BMC PF00936.19 EAU91510.1 - 0.18 11.8 2.5 1.7 8.7 0.3 2.8 2 0 0 2 2 2 0 BMC domain Pardaxin PF07425.11 EAU91510.1 - 0.97 9.1 4.6 4.5 7.0 4.6 2.2 1 0 0 1 1 1 0 Pardaxin AAA_11 PF13086.6 EAU91511.2 - 9.2e-32 110.8 0.0 4.5e-15 56.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_12 PF13087.6 EAU91511.2 - 1.4e-12 47.7 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU91511.2 - 4.2e-08 33.1 0.0 3e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU91511.2 - 6.2e-07 29.8 0.0 3.4e-05 24.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_9 PF13371.6 EAU91511.2 - 0.023 14.9 0.0 0.38 10.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec7 PF01369.20 EAU91511.2 - 0.03 14.0 0.1 0.34 10.6 0.1 2.6 2 1 0 2 2 2 0 Sec7 domain DUF2075 PF09848.9 EAU91511.2 - 0.048 12.9 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EAU91511.2 - 0.059 13.4 0.0 0.26 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EAU91511.2 - 0.081 12.3 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 EAU91511.2 - 0.084 12.4 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SHE3 PF17078.5 EAU91511.2 - 0.13 11.9 0.7 0.42 10.3 0.1 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 UvrD-helicase PF00580.21 EAU91511.2 - 0.16 11.4 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain LCAT PF02450.15 EAU91513.2 - 2.3e-84 283.8 0.0 5e-84 282.7 0.0 1.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EAU91513.2 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 EAU91513.2 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Lipase_2 PF01674.18 EAU91513.2 - 0.042 13.4 0.1 0.14 11.7 0.1 1.9 1 1 0 1 1 1 0 Lipase (class 2) Abhydrolase_6 PF12697.7 EAU91513.2 - 0.073 13.7 0.0 0.23 12.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU91513.2 - 0.087 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EAU91513.2 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DMPK_coil PF08826.10 EAU91513.2 - 0.25 11.5 1.2 0.42 10.7 0.2 1.8 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF2229 PF09989.9 EAU91514.1 - 0.051 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) ACTH_assoc PF16102.5 EAU91514.1 - 0.086 13.6 0.0 31 5.6 0.0 2.6 2 0 0 2 2 2 0 ACTH-associated domain Dimerisation2 PF16864.5 EAU91514.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Trp_halogenase PF04820.14 EAU91515.2 - 7.5e-28 97.6 1.0 1.2e-15 57.4 0.0 2.9 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EAU91515.2 - 8.4e-12 45.0 0.0 2.1e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EAU91515.2 - 7.2e-07 29.3 0.7 4.6e-06 26.8 0.1 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU91515.2 - 6.6e-06 25.6 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU91515.2 - 9.7e-06 24.5 0.2 4e-05 22.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EAU91515.2 - 1.5e-05 24.8 0.3 0.00025 20.8 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EAU91515.2 - 2.7e-05 23.7 0.0 4.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EAU91515.2 - 3.5e-05 23.1 0.1 5.4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EAU91515.2 - 6.5e-05 22.2 0.2 0.00012 21.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EAU91515.2 - 0.00011 22.7 0.0 0.0027 18.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EAU91515.2 - 0.0028 16.8 0.1 0.0057 15.8 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EAU91515.2 - 0.0088 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EAU91515.2 - 0.01 15.1 0.2 0.084 12.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 EAU91515.2 - 0.02 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EAU91515.2 - 0.037 14.5 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EAU91515.2 - 0.061 13.3 0.5 0.82 9.6 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 EAU91515.2 - 0.17 11.5 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Solute_trans_a PF03619.16 EAU91516.2 - 2.8e-78 263.1 11.0 3.5e-78 262.8 11.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha IGPS PF00218.21 EAU91517.1 - 1.5e-88 296.2 0.0 2.8e-88 295.4 0.0 1.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EAU91517.1 - 2.7e-44 151.2 0.0 4.4e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 EAU91517.1 - 6.8e-40 136.9 0.7 1.3e-18 67.5 0.0 3.3 3 0 0 3 3 3 3 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 EAU91517.1 - 1.3e-06 28.3 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EAU91517.1 - 0.7 9.6 2.1 1.7 8.4 0.0 2.6 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain Pkinase PF00069.25 EAU91518.2 - 4.6e-67 226.2 0.0 5.6e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91518.2 - 3e-29 102.1 0.0 4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 EAU91518.2 - 0.013 16.4 0.0 0.041 14.8 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Haspin_kinase PF12330.8 EAU91518.2 - 0.028 13.4 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EAU91518.2 - 0.034 14.1 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EAU91518.2 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tetraspanin PF00335.20 EAU91519.1 - 0.00016 21.5 8.8 0.00023 21.0 8.8 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2569 PF10754.9 EAU91519.1 - 0.012 16.0 2.9 0.017 15.5 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) PhoLip_ATPase_C PF16212.5 EAU91520.2 - 7.5e-82 274.8 23.1 7.5e-82 274.8 23.1 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EAU91520.2 - 6.6e-27 93.0 6.3 2.2e-26 91.3 6.3 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EAU91520.2 - 1.3e-12 47.6 0.0 5.3e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EAU91520.2 - 5.3e-11 43.2 1.1 9.7e-06 26.0 0.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EAU91520.2 - 2.6e-08 33.6 0.7 6.8e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EAU91520.2 - 0.0047 16.7 0.1 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RsgI_N PF12791.7 EAU91520.2 - 0.1 12.5 0.1 0.8 9.7 0.0 2.3 2 0 0 2 2 2 0 Anti-sigma factor N-terminus Abhydrolase_1 PF00561.20 EAU91522.1 - 9.3e-26 91.0 0.2 6.4e-25 88.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EAU91522.1 - 1.7e-23 82.0 0.1 3.4e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EAU91522.1 - 2.8e-06 26.8 0.0 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Glucosamine_iso PF01182.20 EAU91524.2 - 3.5e-18 66.3 0.0 6.9e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 EAU91524.2 - 0.038 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain zf-C2H2 PF00096.26 EAU91525.1 - 1.2e-24 85.3 81.1 0.00013 22.3 1.2 11.2 11 1 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU91525.1 - 9.8e-18 63.3 68.4 0.0029 18.3 2.2 10.7 10 0 0 10 10 10 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU91525.1 - 5.8e-12 45.5 68.8 8.4e-06 26.0 1.1 11.6 12 0 0 12 12 12 5 Zinc-finger double domain zf-C2H2_8 PF15909.5 EAU91525.1 - 8.2e-09 35.7 30.2 0.056 13.7 6.9 5.9 3 1 3 6 6 6 4 C2H2-type zinc ribbon FYDLN_acid PF09538.10 EAU91525.1 - 0.0028 18.3 3.2 0.28 11.9 0.1 3.8 4 0 0 4 4 4 1 Protein of unknown function (FYDLN_acid) zf-C2H2_jaz PF12171.8 EAU91525.1 - 0.0048 17.1 36.5 0.021 15.1 0.8 8.8 9 0 0 9 9 9 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EAU91525.1 - 0.013 15.5 46.6 0.024 14.6 1.5 8.1 8 0 0 8 8 8 0 C2H2-type zinc finger zf-met PF12874.7 EAU91525.1 - 0.023 15.1 1.7 0.023 15.1 1.7 7.1 8 0 0 8 8 7 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 EAU91525.1 - 0.33 10.6 13.9 1.1 9.0 0.5 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf_ZIC PF18366.1 EAU91525.1 - 0.65 10.2 0.0 0.65 10.2 0.0 6.1 8 0 0 8 8 8 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 EAU91525.1 - 7.2 6.7 24.0 7.9 6.6 0.1 5.8 4 2 1 6 6 6 0 Aberrant zinc-finger GIT_SHD PF08518.11 EAU91529.2 - 7.7e-27 92.6 4.6 1.7e-14 53.2 0.6 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT AIP3 PF03915.13 EAU91529.2 - 0.19 10.8 19.2 0.06 12.4 15.2 2.0 2 0 0 2 2 2 0 Actin interacting protein 3 DUF4686 PF15742.5 EAU91529.2 - 0.67 9.0 26.5 1.1 8.3 26.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF1664 PF07889.12 EAU91529.2 - 0.91 9.6 11.1 9.7 6.3 4.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 EAU91529.2 - 1.3 8.6 27.8 1.3 8.7 19.6 3.2 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EAU91529.2 - 1.5 7.6 26.5 0.46 9.3 6.0 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 EAU91529.2 - 2.7 7.4 34.8 0.022 14.3 20.3 2.5 2 1 1 3 3 3 0 Golgin subfamily A member 5 TPR_MLP1_2 PF07926.12 EAU91529.2 - 3.1 7.9 33.7 1 9.4 1.1 4.1 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein HemX PF04375.14 EAU91529.2 - 4.3 6.5 20.0 0.46 9.7 11.9 2.5 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FlaC_arch PF05377.11 EAU91529.2 - 5.6 7.4 12.9 6.4 7.3 1.7 4.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) SpecificRecomb PF10136.9 EAU91529.2 - 5.6 5.1 7.3 0.77 8.0 2.4 2.0 2 0 0 2 2 2 0 Site-specific recombinase adh_short PF00106.25 EAU91530.1 - 9.3e-38 129.6 1.0 1.3e-37 129.2 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU91530.1 - 3.9e-20 72.4 0.1 5.2e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU91530.1 - 0.0049 16.8 0.2 0.015 15.2 0.2 1.7 1 1 0 1 1 1 1 KR domain DUF2272 PF10030.9 EAU91530.1 - 0.096 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) Pyridoxal_deC PF00282.19 EAU91531.2 - 6e-107 357.6 0.0 7.2e-107 357.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.29 EAU91532.2 - 5.7e-57 191.8 0.0 1.6e-43 148.3 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EAU91532.2 - 6e-24 84.3 0.7 1.5e-23 83.0 0.7 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EAU91532.2 - 8.1e-17 60.8 0.0 3.5e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EAU91532.2 - 1.2e-12 48.5 4.4 3.1e-05 24.4 0.1 4.5 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EAU91532.2 - 8.6e-08 32.5 0.5 0.056 13.7 0.0 4.9 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.6 EAU91532.2 - 3e-07 31.1 0.0 0.017 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EAU91532.2 - 1.1e-06 28.7 0.0 0.021 14.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EAU91532.2 - 2.1e-06 27.9 0.0 0.043 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EAU91532.2 - 2.3e-06 27.5 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EAU91532.2 - 6.9e-06 26.1 0.1 0.078 12.9 0.0 4.0 3 1 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 EAU91532.2 - 4.7e-05 23.2 0.0 0.0027 17.5 0.0 2.7 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EAU91532.2 - 6.1e-05 23.1 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EAU91532.2 - 0.0002 21.0 0.9 1.2 8.6 0.1 4.0 2 2 1 4 4 4 1 AAA domain AAA_17 PF13207.6 EAU91532.2 - 0.00036 21.0 0.1 0.33 11.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EAU91532.2 - 0.00046 20.1 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EAU91532.2 - 0.00066 19.0 0.0 0.75 9.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.14 EAU91532.2 - 0.00081 19.5 0.0 0.049 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EAU91532.2 - 0.00083 18.8 0.0 0.64 9.4 0.0 3.0 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EAU91532.2 - 0.00084 18.6 0.0 0.089 12.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain RNA_helicase PF00910.22 EAU91532.2 - 0.00092 19.6 0.0 0.96 9.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase TsaE PF02367.17 EAU91532.2 - 0.0017 18.3 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EAU91532.2 - 0.0018 17.5 0.0 1.7 7.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.15 EAU91532.2 - 0.0024 17.8 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain DUF2075 PF09848.9 EAU91532.2 - 0.0053 16.1 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EAU91532.2 - 0.0086 16.0 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 NTPase ABC_tran PF00005.27 EAU91532.2 - 0.0087 16.6 0.0 2.3 8.8 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_7 PF12775.7 EAU91532.2 - 0.012 15.1 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EAU91532.2 - 0.012 14.7 0.0 0.48 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EAU91532.2 - 0.016 15.0 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EAU91532.2 - 0.016 15.1 0.1 1.5 8.6 0.0 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 EAU91532.2 - 0.023 14.6 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase KTI12 PF08433.10 EAU91532.2 - 0.024 14.1 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 EAU91532.2 - 0.024 14.9 0.1 0.93 9.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 EAU91532.2 - 0.027 14.2 0.0 0.58 9.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EAU91532.2 - 0.054 13.2 0.0 12 5.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAU91532.2 - 0.065 12.9 0.0 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EAU91532.2 - 0.072 13.1 0.1 0.75 9.8 0.1 2.6 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.18 EAU91532.2 - 0.073 12.9 0.0 11 5.8 0.0 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein SKI PF01202.22 EAU91532.2 - 0.086 13.0 0.4 3.3 7.8 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase Cytidylate_kin2 PF13189.6 EAU91532.2 - 0.11 12.6 0.0 0.42 10.7 0.0 2.0 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_28 PF13521.6 EAU91532.2 - 0.13 12.5 0.0 8.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EAU91532.2 - 0.22 11.1 0.5 3.8 7.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mito_carr PF00153.27 EAU91535.1 - 1.2e-53 179.0 3.3 6.6e-22 77.3 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAU91535.1 - 0.14 11.3 0.1 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease TBPIP PF07106.13 EAU91536.2 - 5.8e-18 64.6 0.1 1.3e-17 63.5 0.1 1.6 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 EAU91536.2 - 5e-05 23.6 0.4 0.0002 21.7 0.1 2.1 1 1 0 2 2 2 1 Penicillinase repressor ZapB PF06005.12 EAU91536.2 - 0.00075 19.9 12.5 0.16 12.4 3.3 2.6 1 1 1 2 2 2 2 Cell division protein ZapB LPP PF04728.13 EAU91536.2 - 0.0012 19.1 2.3 0.61 10.5 0.6 2.7 2 1 0 2 2 2 1 Lipoprotein leucine-zipper Phage_GP20 PF06810.11 EAU91536.2 - 0.0015 18.4 5.5 0.0016 18.2 3.8 1.9 2 0 0 2 2 2 1 Phage minor structural protein GP20 LRRFIP PF09738.9 EAU91536.2 - 0.0026 17.3 3.3 0.0035 16.9 3.3 1.3 1 0 0 1 1 1 1 LRRFIP family K-box PF01486.17 EAU91536.2 - 0.0054 16.9 3.3 0.25 11.6 0.1 2.5 1 1 0 2 2 2 1 K-box region LCD1 PF09798.9 EAU91536.2 - 0.0067 15.0 0.6 0.0082 14.7 0.6 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein HTH_IclR PF09339.10 EAU91536.2 - 0.012 15.3 0.0 0.045 13.6 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain DivIC PF04977.15 EAU91536.2 - 0.013 15.3 5.6 0.095 12.5 0.7 2.7 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 EAU91536.2 - 0.013 16.1 5.2 0.21 12.3 3.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Bacillus_HBL PF05791.11 EAU91536.2 - 0.022 14.6 0.7 0.038 13.8 0.7 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TSC22 PF01166.18 EAU91536.2 - 0.024 14.9 5.2 3.4 8.1 1.0 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 EAU91536.2 - 0.029 14.5 6.4 2.2 8.5 1.5 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 TrmB PF01978.19 EAU91536.2 - 0.03 14.2 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB bZIP_1 PF00170.21 EAU91536.2 - 0.041 14.0 11.1 0.057 13.5 2.7 2.9 2 1 1 3 3 2 0 bZIP transcription factor z-alpha PF02295.17 EAU91536.2 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain FlaC_arch PF05377.11 EAU91536.2 - 0.092 13.2 5.5 0.67 10.4 1.0 2.7 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2312 PF10073.9 EAU91536.2 - 0.099 12.3 1.8 0.81 9.4 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) YlqD PF11068.8 EAU91536.2 - 0.14 12.5 6.6 0.93 9.9 6.0 2.1 1 1 1 2 2 2 0 YlqD protein Herpes_BLRF2 PF05812.12 EAU91536.2 - 0.15 12.2 6.1 0.59 10.3 0.4 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein MscS_porin PF12795.7 EAU91536.2 - 0.15 11.5 12.2 0.1 12.1 10.5 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FlxA PF14282.6 EAU91536.2 - 0.18 11.8 7.9 0.42 10.6 7.9 1.6 1 1 0 1 1 1 0 FlxA-like protein Prominin PF05478.11 EAU91536.2 - 0.2 9.6 1.9 0.24 9.3 1.9 1.1 1 0 0 1 1 1 0 Prominin CENP-H PF05837.12 EAU91536.2 - 0.23 11.9 12.2 0.13 12.6 6.6 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Nnf1 PF03980.14 EAU91536.2 - 0.39 11.1 8.6 3.3 8.1 1.1 2.6 1 1 1 2 2 2 0 Nnf1 Cep57_MT_bd PF06657.13 EAU91536.2 - 0.44 11.0 5.6 0.43 11.1 3.2 2.2 2 1 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 HALZ PF02183.18 EAU91536.2 - 0.58 10.4 4.8 11 6.3 0.8 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF5595 PF18077.1 EAU91536.2 - 0.58 10.3 2.7 1.3 9.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DLP_helical PF18709.1 EAU91536.2 - 1.2 8.3 8.9 3.7 6.6 3.0 2.3 1 1 1 2 2 2 0 Dynamin-like helical domain ADIP PF11559.8 EAU91536.2 - 1.4 8.9 8.8 0.83 9.7 1.7 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rootletin PF15035.6 EAU91536.2 - 1.5 8.9 12.7 1.4 9.0 4.1 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 EAU91536.2 - 1.5 9.4 11.7 10 6.7 10.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region GrpE PF01025.19 EAU91536.2 - 1.7 8.3 9.8 8.2 6.1 4.3 3.2 1 1 2 3 3 3 0 GrpE TMF_TATA_bd PF12325.8 EAU91536.2 - 1.9 8.8 12.6 0.88 9.8 8.7 2.4 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding ABC_tran_CTD PF16326.5 EAU91536.2 - 2 8.8 14.9 7.9 6.8 5.3 3.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Spc24 PF08286.11 EAU91536.2 - 2 8.7 8.8 52 4.2 8.7 2.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.15 EAU91536.2 - 2.7 8.1 13.9 1.2 9.2 0.5 3.0 3 0 0 3 3 2 0 Basic region leucine zipper Swi5 PF07061.11 EAU91536.2 - 2.7 8.1 6.5 23 5.1 4.6 2.8 1 1 1 2 2 2 0 Swi5 GIT_CC PF16559.5 EAU91536.2 - 5.6 6.9 10.2 11 6.0 0.3 3.3 1 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPR_MLP1_2 PF07926.12 EAU91536.2 - 7.4 6.7 14.7 1.2 9.2 8.9 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ras PF00071.22 EAU91537.2 - 1.6e-49 167.6 0.0 1.9e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU91537.2 - 1.1e-23 83.7 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU91537.2 - 1.9e-05 24.2 0.0 4.2e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 EAU91537.2 - 0.015 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3937 PF13073.6 EAU91539.1 - 0.014 15.5 1.7 0.083 13.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) G-patch_2 PF12656.7 EAU91540.2 - 3.7e-24 84.6 0.3 1.1e-23 83.1 0.3 1.9 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 EAU91540.2 - 0.0022 17.8 0.8 0.007 16.2 0.8 2.0 1 0 0 1 1 1 1 G-patch domain AA_permease PF00324.21 EAU91543.2 - 1.1e-83 281.5 37.1 7.7e-72 242.4 27.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EAU91543.2 - 2e-17 63.1 30.9 2e-17 63.1 30.9 2.0 1 1 1 2 2 2 1 Amino acid permease NTP_transferase PF00483.23 EAU91544.1 - 1.1e-41 143.0 0.0 2.7e-41 141.8 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EAU91544.1 - 1.7e-07 31.7 0.1 3.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.18 EAU91544.1 - 0.00019 21.3 0.1 0.00034 20.5 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.19 EAU91544.1 - 0.0085 15.9 0.0 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF364 PF04016.12 EAU91544.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative heavy-metal chelation G-alpha PF00503.20 EAU91545.2 - 2.6e-109 365.7 0.0 3.6e-109 365.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU91545.2 - 7e-06 25.6 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 EAU91545.2 - 0.018 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EAU91545.2 - 0.03 14.1 0.0 0.079 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EAU91545.2 - 0.13 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU91546.2 - 2.9e-06 27.8 1.5 0.0048 17.5 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EAU91546.2 - 0.0015 18.7 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EAU91546.2 - 0.051 13.8 0.1 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EAU91546.2 - 0.052 13.3 0.1 0.44 10.2 0.0 2.1 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FAD_binding_2 PF00890.24 EAU91547.1 - 1e-87 294.9 1.0 1.5e-87 294.4 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EAU91547.1 - 4e-23 81.3 0.3 2.2e-22 79.0 0.0 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EAU91547.1 - 1.6e-13 51.0 1.0 1.4e-12 47.8 0.7 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU91547.1 - 1.3e-10 41.4 0.1 7.9e-10 38.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU91547.1 - 2.9e-10 39.9 0.4 1e-08 34.8 0.2 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EAU91547.1 - 1.9e-09 37.4 0.9 3.6e-09 36.5 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EAU91547.1 - 4.4e-06 26.0 3.2 9.8e-05 21.6 0.5 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EAU91547.1 - 5.6e-06 25.8 1.6 1.1e-05 24.9 1.6 1.6 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EAU91547.1 - 4.1e-05 22.5 6.4 7.9e-05 21.5 0.7 2.9 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 EAU91547.1 - 9.2e-05 21.9 1.1 0.0038 16.6 0.5 2.9 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EAU91547.1 - 0.0002 20.8 0.3 0.00035 19.9 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EAU91547.1 - 0.00023 20.5 1.7 0.032 13.5 0.4 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 EAU91547.1 - 0.00033 20.0 0.3 0.2 10.9 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EAU91547.1 - 0.00055 20.4 0.5 0.034 14.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU91547.1 - 0.001 19.1 0.3 0.0039 17.2 0.3 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EAU91547.1 - 0.01 14.9 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EAU91547.1 - 0.047 14.1 0.0 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_M19 PF01244.21 EAU91548.2 - 2e-104 349.2 0.0 2.4e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) GET2 PF08690.10 EAU91548.2 - 0.012 15.3 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 G-alpha PF00503.20 EAU91549.1 - 1.2e-105 353.5 0.3 1.5e-105 353.3 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU91549.1 - 6.7e-09 35.4 0.5 1e-05 25.0 0.0 2.7 2 1 0 3 3 3 2 ADP-ribosylation factor family TniB PF05621.11 EAU91549.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 EAU91549.1 - 0.031 13.8 0.0 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EAU91549.1 - 0.032 14.6 1.1 0.066 13.6 1.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EAU91549.1 - 0.082 13.1 0.0 22 5.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EAU91549.1 - 0.14 12.5 0.1 0.54 10.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain SAM_2 PF07647.17 EAU91550.1 - 0.0021 18.1 0.1 0.0066 16.5 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EAU91550.1 - 0.0027 18.1 0.0 0.0091 16.4 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) O-FucT PF10250.9 EAU91551.1 - 4.7e-14 52.8 0.0 8.7e-07 28.9 0.0 3.3 1 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Hydrolase_like PF13242.6 EAU91552.2 - 3.7e-29 100.6 0.0 1.1e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EAU91552.2 - 1.8e-24 85.7 0.0 3.1e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU91552.2 - 0.0048 17.2 0.0 3.3 8.0 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Git3 PF11710.8 EAU91554.2 - 0.96 9.2 21.9 0.035 13.9 15.9 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Fungal_trans PF04082.18 EAU91555.2 - 1.3e-07 30.9 0.1 2.4e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU91555.2 - 6.5e-06 26.2 11.9 1.1e-05 25.4 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPT PF03151.16 EAU91556.2 - 6.1e-22 78.3 15.1 8.1e-22 77.9 15.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAU91556.2 - 8.6e-08 32.4 34.2 2.2e-06 27.9 14.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EAU91556.2 - 2.8e-05 23.5 16.1 4.4e-05 22.9 16.1 1.3 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EAU91556.2 - 0.0033 16.7 14.9 0.019 14.2 14.9 2.1 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport Med31 PF05669.12 EAU91557.1 - 5.4e-35 119.3 8.9 6.8e-35 119.0 8.9 1.1 1 0 0 1 1 1 1 SOH1 Peptidase_C12 PF01088.21 EAU91558.1 - 2.2e-52 177.9 0.0 5e-52 176.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EAU91558.1 - 1.7e-13 50.2 0.3 4.2e-13 49.0 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases MyTH4 PF00784.17 EAU91559.2 - 7.5e-30 103.6 0.0 1.7e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 EAU91559.2 - 1.4e-28 99.7 0.0 2.6e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 EAU91559.2 - 1.7e-08 34.4 5.3 6.8e-05 22.9 2.6 2.5 2 0 0 2 2 2 2 WW domain p450 PF00067.22 EAU91561.1 - 1.3e-75 254.9 0.0 2.3e-75 254.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ECH_1 PF00378.20 EAU91562.1 - 2.5e-82 276.0 0.7 2.9e-82 275.8 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAU91562.1 - 5.5e-36 124.7 0.9 1.6e-32 113.3 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase DUF3645 PF12359.8 EAU91562.1 - 0.15 11.4 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) YCII PF03795.14 EAU91563.2 - 1e-05 25.9 0.0 1.3e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.14 EAU91564.1 - 2.7e-09 37.3 0.0 3.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.14 EAU91565.1 - 3.5e-10 40.1 0.0 4.7e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain BTB PF00651.31 EAU91566.2 - 5.3e-06 26.6 0.0 9.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-RING_UBOX PF13445.6 EAU91567.2 - 4.4e-08 33.0 3.0 4.4e-08 33.0 3.0 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EAU91567.2 - 5.6e-07 29.3 2.4 5.6e-07 29.3 2.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU91567.2 - 2.5e-06 27.2 3.2 2.5e-06 27.2 3.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU91567.2 - 6.9e-06 26.3 3.1 6.9e-06 26.3 3.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 EAU91567.2 - 1.7e-05 24.6 0.9 3.4e-05 23.6 0.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EAU91567.2 - 1.9e-05 24.5 6.3 8.6e-05 22.4 3.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EAU91567.2 - 0.00045 20.0 6.6 0.0044 16.8 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU91567.2 - 0.00059 19.9 2.8 0.00059 19.9 2.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING ADIP PF11559.8 EAU91567.2 - 0.0016 18.5 1.1 0.0023 18.0 1.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4795 PF16043.5 EAU91567.2 - 0.004 16.8 1.1 0.0061 16.2 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 EAU91567.2 - 0.0041 17.3 0.6 0.0065 16.7 0.6 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 EAU91567.2 - 0.015 15.8 2.2 0.025 15.0 2.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB DUF948 PF06103.11 EAU91567.2 - 0.017 15.4 0.6 0.029 14.6 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Prok-RING_4 PF14447.6 EAU91567.2 - 0.023 14.6 2.1 0.023 14.6 2.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Leu_zip PF15294.6 EAU91567.2 - 0.026 14.0 0.0 0.034 13.7 0.0 1.1 1 0 0 1 1 1 0 Leucine zipper Cnn_1N PF07989.11 EAU91567.2 - 0.034 14.3 0.3 0.11 12.7 0.2 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Baculo_IE-1 PF05290.11 EAU91567.2 - 0.037 14.0 0.5 0.037 14.0 0.5 1.5 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) Laminin_I PF06008.14 EAU91567.2 - 0.043 13.5 0.1 0.062 13.0 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain I LPP PF04728.13 EAU91567.2 - 0.045 14.1 0.4 0.089 13.2 0.4 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper GOLGA2L5 PF15070.6 EAU91567.2 - 0.049 12.3 0.3 0.068 11.8 0.3 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 TMF_DNA_bd PF12329.8 EAU91567.2 - 0.05 13.6 1.2 0.075 13.0 1.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PspA_IM30 PF04012.12 EAU91567.2 - 0.064 12.8 1.2 0.094 12.3 1.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family zf-CpG_bind_C PF12269.8 EAU91567.2 - 0.079 12.7 0.6 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain DivIC PF04977.15 EAU91567.2 - 0.087 12.6 2.1 0.14 11.9 2.1 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4446 PF14584.6 EAU91567.2 - 0.11 12.5 0.3 0.16 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Cep57_MT_bd PF06657.13 EAU91567.2 - 0.11 12.9 0.7 0.11 12.9 0.7 1.5 2 0 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 Rho_Binding PF08912.11 EAU91567.2 - 0.14 13.0 1.8 0.21 12.4 1.8 1.2 1 0 0 1 1 1 0 Rho Binding Prominin PF05478.11 EAU91567.2 - 0.16 9.9 0.2 0.19 9.6 0.2 1.1 1 0 0 1 1 1 0 Prominin DUF4404 PF14357.6 EAU91567.2 - 0.18 12.5 1.6 0.34 11.6 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) zf-RING_10 PF16685.5 EAU91567.2 - 0.2 11.8 3.1 0.18 12.0 1.1 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 DUF4407 PF14362.6 EAU91567.2 - 0.2 11.0 0.1 0.28 10.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EAU91567.2 - 0.25 10.2 1.7 0.35 9.7 1.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-rbx1 PF12678.7 EAU91567.2 - 0.27 11.6 7.9 0.19 12.1 3.6 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EAU91567.2 - 0.29 10.8 3.1 0.22 11.2 1.1 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EAU91567.2 - 0.37 10.6 4.7 1 9.2 4.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EAU91567.2 - 0.44 10.6 3.9 0.5 10.5 0.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Swi5 PF07061.11 EAU91567.2 - 1.2 9.3 3.8 1.4 9.1 1.5 2.0 2 0 0 2 2 2 0 Swi5 SlyX PF04102.12 EAU91567.2 - 2.9 8.6 7.9 0.27 11.9 0.6 2.7 3 0 0 3 3 2 0 SlyX FANCL_C PF11793.8 EAU91567.2 - 6.9 6.9 11.1 2.3 8.4 4.5 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain Caskin-Pro-rich PF16907.5 EAU91567.2 - 7.4 7.2 10.8 3.9 8.1 4.0 2.5 2 0 0 2 2 2 0 Proline rich region of Caskin proteins RSN1_7TM PF02714.15 EAU91569.2 - 4.6e-55 186.9 23.5 2.7e-30 105.6 3.1 3.3 2 1 1 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EAU91569.2 - 4.9e-39 133.6 1.8 1.2e-38 132.3 1.8 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EAU91569.2 - 1.5e-24 87.2 0.1 1.5e-24 87.2 0.1 2.6 2 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EAU91569.2 - 1.6e-13 50.6 0.2 4.4e-13 49.2 0.2 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter HEAT PF02985.22 EAU91570.2 - 8.8e-09 34.9 0.8 0.38 11.1 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EAU91570.2 - 1.4e-06 28.6 0.1 0.0095 16.3 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Pkinase PF00069.25 EAU91570.2 - 1.3e-05 24.7 0.0 3.9e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 EAU91570.2 - 2.2e-05 24.6 0.1 0.0051 16.9 0.0 2.6 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EAU91570.2 - 0.0055 17.2 2.5 0.45 11.1 0.1 4.1 3 2 2 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 EAU91570.2 - 0.0069 15.0 0.0 2.5 6.5 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Med14 PF08638.11 EAU91571.2 - 9.5e-55 185.0 0.1 2e-54 184.0 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 MSA-2c PF12238.8 EAU91571.2 - 0.77 9.7 4.3 1.6 8.6 4.3 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c FANCL_C PF11793.8 EAU91572.1 - 0.047 13.9 1.5 0.092 12.9 1.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 EAU91572.1 - 0.067 13.5 3.4 0.15 12.4 3.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 EAU91572.1 - 0.32 11.3 1.4 0.57 10.5 0.1 1.9 2 0 0 2 2 2 0 RING-like domain Acetyltransf_1 PF00583.25 EAU91573.2 - 6.1e-10 39.4 0.0 1.2e-05 25.5 0.0 2.9 3 1 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAU91573.2 - 1.7e-06 28.4 0.0 6.3e-05 23.3 0.0 3.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU91573.2 - 7.2e-06 25.9 0.0 0.084 12.9 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 EAU91573.2 - 0.00061 19.7 0.0 0.22 11.5 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EAU91573.2 - 0.012 15.1 0.0 0.028 13.9 0.0 1.7 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 EAU91573.2 - 0.052 14.2 0.0 0.99 10.1 0.0 2.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAU91573.2 - 0.14 12.3 0.0 2.1 8.5 0.0 2.5 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase PEPCK_ATP PF01293.20 EAU91574.2 - 6.7e-195 648.2 0.0 3.3e-193 642.6 0.0 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.6 EAU91574.2 - 0.02 14.6 0.1 0.054 13.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EAU91574.2 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Amidohydro_2 PF04909.14 EAU91576.2 - 2.7e-05 24.1 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Yae1_N PF09811.9 EAU91576.2 - 0.00095 18.8 13.0 0.044 13.5 8.1 2.8 1 1 1 2 2 2 2 Essential protein Yae1, N terminal APG6_N PF17675.1 EAU91576.2 - 0.011 16.2 19.5 0.023 15.2 19.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region ATG16 PF08614.11 EAU91576.2 - 0.061 13.5 19.2 0.1 12.8 19.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ERM PF00769.19 EAU91576.2 - 0.66 9.7 18.7 1.1 9.1 18.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family BRE1 PF08647.11 EAU91576.2 - 1.3 9.1 11.2 0.091 12.8 3.6 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FPP PF05911.11 EAU91576.2 - 1.8 6.7 16.5 2.2 6.4 16.5 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Snf7 PF03357.21 EAU91576.2 - 7.7 6.1 12.7 1.9 8.1 7.2 2.1 2 0 0 2 2 2 0 Snf7 DUF3636 PF12331.8 EAU91578.2 - 0.0048 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) Pex24p PF06398.11 EAU91578.2 - 0.3 10.0 1.9 0.46 9.4 0.6 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF4407 PF14362.6 EAU91578.2 - 0.8 9.0 7.0 1.3 8.3 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 EAU91578.2 - 0.99 9.7 9.2 1.9 8.8 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) L_lactis_ph-MCP PF06673.11 EAU91578.2 - 0.99 8.3 3.1 1.7 7.6 3.1 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein T2SSM PF04612.12 EAU91578.2 - 1.1 9.2 5.2 2.7 8.0 5.2 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M V_ATPase_I PF01496.19 EAU91578.2 - 1.3 6.8 4.8 1.9 6.3 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EAU91578.2 - 1.9 7.5 6.2 3.2 6.8 6.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EAU91578.2 - 2 7.2 12.1 3.3 6.5 12.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 EAU91578.2 - 3.6 6.0 14.2 6 5.3 14.2 1.2 1 0 0 1 1 1 0 Macoilin family Jnk-SapK_ap_N PF09744.9 EAU91578.2 - 3.8 7.7 14.0 7.3 6.8 14.0 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ASL_C PF08328.11 EAU91578.2 - 10 6.3 7.1 21 5.3 7.1 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal SNase PF00565.17 EAU91580.2 - 2.9e-60 201.5 0.1 9.5e-21 74.3 0.1 5.8 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EAU91580.2 - 8.1e-21 74.3 0.0 1.4e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 EAU91580.2 - 0.0012 19.3 0.1 0.0066 16.9 0.0 2.4 3 0 0 3 3 3 1 Agenet domain Peptidase_S41 PF03572.18 EAU91581.2 - 2e-06 27.5 0.0 9.5e-06 25.3 0.0 2.0 2 1 0 2 2 2 1 Peptidase family S41 HAD_2 PF13419.6 EAU91582.1 - 3.3e-18 66.4 0.0 5.4e-18 65.7 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU91582.1 - 2.8e-14 53.9 0.0 3.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU91582.1 - 5.2e-12 45.7 0.0 2.4e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EAU91582.1 - 0.0088 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EAU91582.1 - 0.1 13.0 0.0 1.8 8.9 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_S6 PF01250.17 EAU91583.1 - 1.6e-20 73.2 0.0 2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Zeta_toxin PF06414.12 EAU91584.2 - 0.00088 18.6 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin DUF5312 PF17239.2 EAU91584.2 - 0.0052 15.2 0.5 0.0071 14.7 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5312) AAA_16 PF13191.6 EAU91584.2 - 0.0086 16.5 0.1 0.021 15.2 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EAU91584.2 - 0.029 14.9 0.0 0.061 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EAU91584.2 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.11 EAU91584.2 - 0.074 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.6 EAU91584.2 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EAU91584.2 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Rer1 PF03248.13 EAU91585.2 - 1.4e-77 259.3 2.4 1.6e-77 259.1 2.4 1.0 1 0 0 1 1 1 1 Rer1 family Vps55 PF04133.14 EAU91585.2 - 0.1 12.6 0.7 0.1 12.6 0.7 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 55 Sortilin-Vps10 PF15902.5 EAU91586.2 - 1.4e-09 37.2 20.1 0.0028 16.5 0.1 6.4 4 2 3 9 9 9 6 Sortilin, neurotensin receptor 3, BNR PF02012.20 EAU91586.2 - 4.9e-05 22.7 38.1 0.64 10.2 0.9 10.0 10 0 0 10 10 10 4 BNR/Asp-box repeat BNR_6 PF15899.5 EAU91586.2 - 0.00067 19.5 13.1 1.3 9.3 0.1 8.5 9 0 0 9 9 9 1 BNR-Asp box repeat Kelch_4 PF13418.6 EAU91586.2 - 0.032 14.3 0.1 1.7 8.7 0.0 3.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 EAU91586.2 - 0.056 13.0 0.1 18 5.0 0.1 3.0 3 0 0 3 3 3 0 Kelch motif UPF0029 PF01205.19 EAU91587.1 - 3e-25 88.6 0.0 4.6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF615 PF04751.14 EAU91587.1 - 0.012 15.6 0.0 0.94 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF615) CPSase_L_D2 PF02786.17 EAU91591.1 - 2.2e-97 324.7 0.0 1.1e-75 253.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EAU91591.1 - 3.2e-39 134.0 0.8 7.4e-39 132.9 0.8 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EAU91591.1 - 1.6e-15 57.1 0.0 1.2e-06 28.2 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EAU91591.1 - 2.4e-12 46.9 0.1 2e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EAU91591.1 - 1.4e-06 28.1 0.0 0.014 15.2 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EAU91591.1 - 1.2e-05 24.9 0.1 0.024 14.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 EAU91591.1 - 2.4e-05 24.4 0.0 0.046 13.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 EAU91591.1 - 0.016 15.4 0.0 0.085 13.1 0.0 2.4 1 1 0 1 1 1 0 MGS-like domain SdpI PF13630.6 EAU91592.2 - 5.6 7.2 17.0 0.28 11.4 1.1 3.3 3 0 0 3 3 3 0 SdpI/YhfL protein family RNase_T PF00929.24 EAU91593.1 - 3e-25 89.7 0.0 4.4e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.6 EAU91593.1 - 0.1 12.6 0.0 2.8 7.9 0.0 2.1 2 0 0 2 2 2 0 RNase_H superfamily PPTA PF01239.22 EAU91594.1 - 9.3e-07 28.4 6.9 0.0045 16.7 0.1 4.2 5 0 0 5 5 5 2 Protein prenyltransferase alpha subunit repeat V-SNARE_C PF12352.8 EAU91598.2 - 3.3e-15 56.1 0.3 9.1e-15 54.7 0.3 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EAU91598.2 - 2.9e-05 23.9 0.3 0.00012 21.9 0.0 1.9 2 1 0 2 2 2 1 Sec20 FUSC PF04632.12 EAU91598.2 - 0.031 12.8 0.1 0.055 12.0 0.1 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF745 PF05335.13 EAU91598.2 - 0.064 13.0 6.5 0.092 12.5 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Nop25 PF09805.9 EAU91599.1 - 3.5e-24 85.8 23.6 3.5e-24 85.8 23.6 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) FAM72 PF14976.6 EAU91600.2 - 2.7e-13 50.3 7.4 9.6e-12 45.3 7.4 2.1 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 EAU91600.2 - 1.2 9.3 9.1 0.27 11.4 3.3 2.2 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ubiquitin PF00240.23 EAU91601.1 - 2e-136 444.0 19.4 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EAU91601.1 - 3.5e-63 209.4 21.1 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAU91601.1 - 5.1e-23 81.3 9.8 0.00043 20.7 0.2 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EAU91601.1 - 4.5e-16 58.6 3.3 0.03 14.3 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAU91601.1 - 1.8e-14 53.8 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EAU91601.1 - 2.7e-14 53.3 8.2 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 EAU91601.1 - 4.1e-13 49.8 1.2 0.27 11.8 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EAU91601.1 - 6.9e-10 39.0 0.3 1.2 8.9 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EAU91601.1 - 5e-07 29.7 24.7 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EAU91601.1 - 7.3e-07 28.7 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EAU91601.1 - 3.5e-06 27.1 2.8 11 6.3 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 EAU91601.1 - 5.2e-06 27.1 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 EAU91601.1 - 5.9e-06 26.6 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EAU91601.1 - 2.2e-05 24.2 4.2 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 EAU91601.1 - 3.1e-05 24.0 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 EAU91601.1 - 8.1e-05 22.7 3.7 6.6 6.9 0.1 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EAU91601.1 - 0.00032 20.2 0.0 19 4.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 EAU91601.1 - 0.00059 20.4 1.0 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain NEAT PF05031.12 EAU91601.1 - 0.0011 19.5 1.2 1.5 9.4 0.3 2.8 1 1 2 3 3 3 3 Iron Transport-associated domain DUF493 PF04359.14 EAU91601.1 - 0.0027 18.2 0.1 1.3e+02 3.3 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EAU91601.1 - 0.0063 16.6 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EAU91601.1 - 0.021 15.0 5.4 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 EAU91601.1 - 0.09 12.6 9.3 43 4.1 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 EAU91601.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif YcgR_2 PF12945.7 EAU91601.1 - 0.3 11.3 5.0 46 4.3 0.1 4.1 4 0 0 4 4 4 0 Flagellar protein YcgR Phage_sheath_1N PF17481.2 EAU91601.1 - 0.59 10.6 9.4 4.5e+03 -1.8 9.4 4.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain PI3K_p85B PF02192.16 EAU91601.1 - 2.4 8.0 9.0 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 EAU91601.1 - 3.3 7.9 9.8 1e+02 3.2 0.1 4.3 4 0 0 4 4 4 0 Cnl2/NKP2 family protein SET PF00856.28 EAU91602.1 - 1.2e-10 42.0 0.0 1.2e-10 42.0 0.0 4.0 2 2 0 2 2 2 1 SET domain Cpn60_TCP1 PF00118.24 EAU91603.1 - 3.8e-165 550.2 0.3 4.9e-165 549.9 0.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF835 PF05763.12 EAU91606.1 - 0.028 14.1 0.3 3.3 7.4 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF835) PHO4 PF01384.20 EAU91607.2 - 8e-104 347.3 13.9 9.7e-104 347.0 13.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF1673 PF07895.11 EAU91607.2 - 0.083 12.6 0.3 0.24 11.1 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Acetyltransf_3 PF13302.7 EAU91609.1 - 1.1e-12 48.8 0.0 1.5e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU91609.1 - 1.1e-06 28.9 0.0 1.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EAU91609.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arrestin_C PF02752.22 EAU91611.1 - 2.3e-11 44.3 0.0 9.7e-11 42.3 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EAU91611.1 - 3.6e-09 36.8 0.0 4.5e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Tim17 PF02466.19 EAU91612.2 - 2e-31 108.7 11.4 2.4e-31 108.4 11.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Tn7_Tnp_TnsA_C PF08721.11 EAU91613.2 - 0.39 11.4 1.9 1.7 9.3 0.5 2.5 2 1 0 2 2 2 0 TnsA endonuclease C terminal TrkH PF02386.16 EAU91616.2 - 6.6e-100 334.9 15.9 1.6e-96 323.8 7.4 2.1 2 0 0 2 2 2 2 Cation transport protein MIF4G PF02854.19 EAU91617.1 - 2.5e-59 200.5 0.9 7.2e-59 199.0 0.3 2.2 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.8 EAU91617.1 - 1.8e-19 69.7 0.0 7.4e-19 67.7 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 EAU91617.1 - 8.4e-08 32.2 0.1 3.1e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 MA3 domain AAA_16 PF13191.6 EAU91618.2 - 2.4e-05 24.8 0.0 5.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EAU91618.2 - 0.095 12.5 0.2 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-CCCH_2 PF14608.6 EAU91619.2 - 2.5e-16 59.4 32.7 1.2e-05 25.5 2.8 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger M PF02370.16 EAU91619.2 - 1.8 9.4 8.0 5 8.0 8.0 1.8 1 0 0 1 1 1 0 M protein repeat DUF4836 PF16120.5 EAU91619.2 - 7.9 5.3 10.7 0.14 11.1 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4836) Cyclin_N PF00134.23 EAU91620.2 - 3.9e-11 42.8 0.0 7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EAU91620.2 - 1.3e-05 25.6 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin Ribosomal_S5 PF00333.20 EAU91621.1 - 1.3e-28 98.8 0.6 1.3e-28 98.8 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EAU91621.1 - 3.8e-23 80.7 0.0 6.1e-23 80.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ODC_AZ PF02100.17 EAU91622.2 - 1e-14 54.5 0.0 1.5e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1771 PF08590.10 EAU91623.1 - 1.1e-23 83.4 7.9 2.6e-23 82.1 7.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EAU91623.1 - 9e-11 42.0 0.1 1.9e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 EAU91623.1 - 0.017 14.5 0.4 0.018 14.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ApoLp-III PF07464.11 EAU91623.1 - 0.046 13.8 0.4 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SPA PF08616.10 EAU91626.1 - 2.9e-35 120.7 0.0 6.3e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EAU91626.1 - 5.3e-16 59.3 2.6 1.2e-12 48.4 0.2 2.9 3 0 0 3 3 3 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EAU91626.1 - 0.0013 17.5 0.0 2.6 6.6 0.0 3.1 2 1 1 3 3 3 2 Transport protein Avl9 Fungal_trans PF04082.18 EAU91627.1 - 2e-08 33.6 0.1 3e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU91627.1 - 0.14 12.3 9.7 0.26 11.4 9.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CI-B14_5a PF07347.12 EAU91628.1 - 0.0067 16.3 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) G_glu_transpept PF01019.21 EAU91631.2 - 3.1e-150 501.3 0.0 4.4e-150 500.8 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.18 EAU91632.1 - 3.9e-30 105.2 1.9 5.5e-30 104.7 1.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EAU91632.1 - 2.5e-12 46.5 15.1 2.5e-12 46.5 15.1 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 EAU91632.1 - 2.6e-05 23.5 0.0 5.8e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_44 PF12891.7 EAU91632.1 - 0.027 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Toxin_7 PF05980.12 EAU91632.1 - 0.9 9.8 3.1 1.7 8.9 3.1 1.4 1 0 0 1 1 1 0 Toxin 7 Acyltransferase PF01553.21 EAU91635.2 - 3.5e-10 39.6 0.0 2.5e-09 36.8 0.0 2.1 1 1 1 2 2 2 1 Acyltransferase Pkinase PF00069.25 EAU91637.1 - 2.3e-72 243.5 0.0 2.9e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91637.1 - 6.2e-38 130.6 0.0 8.1e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EAU91637.1 - 5.8e-17 61.8 0.7 1e-16 61.0 0.7 1.4 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EAU91637.1 - 3.9e-06 26.4 0.0 6.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAU91637.1 - 0.0019 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAU91637.1 - 0.0067 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAU91637.1 - 0.014 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EAU91637.1 - 0.06 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase S-methyl_trans PF02574.16 EAU91638.1 - 5.6e-45 154.2 0.0 6.9e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Cytochrom_B561 PF03188.16 EAU91639.2 - 1.7e-14 54.1 2.8 2.7e-14 53.4 2.8 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 EAU91639.2 - 3.5e-12 46.4 0.2 4.4e-09 36.3 0.1 2.4 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EAU91639.2 - 1.5e-05 25.2 0.0 4e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 EAU91639.2 - 4.9e-05 23.5 4.9 0.00014 22.0 4.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DUF2427 PF10348.9 EAU91639.2 - 0.0011 18.7 2.7 0.0028 17.4 2.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF2306 PF10067.9 EAU91639.2 - 0.019 15.2 2.9 0.019 15.2 2.9 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) COX15-CtaA PF02628.15 EAU91639.2 - 0.23 10.5 6.7 0.097 11.7 2.9 1.9 1 1 1 2 2 2 0 Cytochrome oxidase assembly protein DUF3382 PF11862.8 EAU91639.2 - 0.55 10.5 4.7 0.24 11.7 0.6 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) DUF4181 PF13789.6 EAU91639.2 - 0.56 10.5 2.0 1.1 9.5 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) API5 PF05918.11 EAU91640.2 - 5.4e-23 81.6 0.4 7.4e-23 81.2 0.4 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 EAU91640.2 - 7.6e-07 29.4 0.2 5e-05 23.6 0.1 3.2 2 0 0 2 2 2 1 HEAT repeats Adaptin_N PF01602.20 EAU91640.2 - 0.025 13.1 0.2 0.05 12.1 0.2 1.5 1 0 0 1 1 1 0 Adaptin N terminal region Ecm29 PF13001.7 EAU91640.2 - 0.05 12.3 0.3 0.11 11.1 0.1 1.6 2 0 0 2 2 2 0 Proteasome stabiliser RE_HaeIII PF09556.10 EAU91640.2 - 0.093 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 HaeIII restriction endonuclease Cnd1 PF12717.7 EAU91640.2 - 0.13 12.2 0.2 0.34 11.0 0.2 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 MmgE_PrpD PF03972.14 EAU91641.2 - 1.7e-158 527.8 0.0 2.1e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PI3_PI4_kinase PF00454.27 EAU91644.2 - 1.4e-20 74.1 0.0 5e-17 62.5 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.22 EAU91645.1 - 1.8e-12 46.9 0.1 2.3e-06 27.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EAU91645.1 - 0.0017 18.5 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 EAU91645.1 - 0.1 12.6 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 EAU91647.2 - 1.7e-49 168.5 0.0 1.2e-35 123.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91647.2 - 5.4e-18 65.2 0.0 5.2e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAU91647.2 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EAU91647.2 - 0.0098 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAU91647.2 - 0.033 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EAU91647.2 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EloA-BP1 PF15870.5 EAU91650.2 - 0.057 13.7 0.6 5.4 7.2 0.1 2.6 2 0 0 2 2 2 0 ElonginA binding-protein 1 LZ3wCH PF18517.1 EAU91651.2 - 1.1e-08 35.0 0.1 2.4e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Mnd1 PF03962.15 EAU91651.2 - 0.00036 20.8 0.2 0.0011 19.3 0.2 1.9 1 0 0 1 1 1 1 Mnd1 HTH domain DivIC PF04977.15 EAU91651.2 - 0.088 12.6 11.2 0.15 11.8 3.2 2.3 1 1 1 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.9 EAU91651.2 - 0.19 11.6 5.2 0.3 11.0 5.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF2624 PF11116.8 EAU91651.2 - 0.35 11.8 2.5 2.2 9.2 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Skp1 PF01466.19 EAU91651.2 - 0.4 10.8 3.9 0.72 10.0 0.0 2.4 2 1 0 2 2 2 0 Skp1 family, dimerisation domain YabA PF06156.13 EAU91651.2 - 0.93 10.2 4.9 1.6 9.4 3.7 1.8 1 1 1 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 EAU91651.2 - 1 9.8 9.5 3.6 8.0 9.4 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) NYD-SP28_assoc PF14775.6 EAU91651.2 - 1.6 8.9 6.0 4.2 7.5 0.8 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain ZapB PF06005.12 EAU91651.2 - 3.9 8.0 11.9 27 5.3 10.9 2.2 1 1 1 2 2 2 0 Cell division protein ZapB zf-MYND PF01753.18 EAU91652.2 - 0.031 14.4 8.1 0.058 13.5 8.1 1.4 1 0 0 1 1 1 0 MYND finger Orn_Arg_deC_N PF02784.16 EAU91652.2 - 0.069 12.5 0.3 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Fungal_trans PF04082.18 EAU91653.1 - 3.4e-08 32.9 0.0 5.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EAU91653.1 - 3.4e-07 30.3 13.6 5.6e-07 29.6 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vac_Fusion PF02346.16 EAU91653.1 - 0.16 11.6 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 W2 PF02020.18 EAU91654.2 - 6e-20 71.2 0.2 6e-20 71.2 0.2 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PP2C PF00481.21 EAU91655.2 - 3.4e-66 223.5 1.1 9.7e-51 172.9 0.2 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EAU91655.2 - 0.0017 18.3 1.0 0.01 15.7 0.7 2.2 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Choline_transpo PF04515.12 EAU91656.1 - 4.2e-79 266.1 13.1 4.2e-79 266.1 13.1 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Amastin PF07344.11 EAU91657.1 - 0.02 14.7 0.5 0.02 14.7 0.5 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein Cellulase PF00150.18 EAU91658.1 - 1.2e-09 38.1 1.6 1.5e-09 37.7 1.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 EAU91658.1 - 0.016 14.9 1.5 0.029 14.0 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 EAU91658.1 - 0.059 12.7 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase FUSC_2 PF13515.6 EAU91659.2 - 6.3e-20 71.6 11.9 6.3e-20 71.6 11.9 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EAU91659.2 - 3.2e-13 49.1 21.9 1.3e-11 43.8 11.0 3.7 4 0 0 4 4 4 3 Fusaric acid resistance protein family ArAE_2 PF10334.9 EAU91659.2 - 2e-11 44.2 0.2 3.6e-10 40.1 0.1 2.4 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EAU91659.2 - 1.7e-07 30.4 9.0 3e-07 29.6 3.6 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter Ribosomal_S8e PF01201.22 EAU91660.1 - 5.4e-56 188.5 0.3 6.4e-56 188.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-RING_11 PF17123.5 EAU91661.2 - 6e-05 22.7 0.2 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_UBOX PF13445.6 EAU91661.2 - 0.031 14.3 0.5 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger DUF1634 PF07843.11 EAU91661.2 - 0.037 14.1 1.4 0.07 13.2 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) zf-RING_2 PF13639.6 EAU91661.2 - 0.049 14.0 0.1 9 6.7 0.0 2.4 2 0 0 2 2 2 0 Ring finger domain PIG-H PF10181.9 EAU91662.2 - 0.19 11.6 0.0 0.56 10.1 0.0 1.7 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component Atg14 PF10186.9 EAU91662.2 - 0.84 8.7 8.8 1.7 7.6 8.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PA26 PF04636.13 EAU91662.2 - 2.2 7.1 5.0 3.7 6.4 5.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GTP_EFTU PF00009.27 EAU91663.2 - 3.2e-18 66.0 0.0 6.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EAU91663.2 - 3.3e-08 33.8 0.6 3.3e-08 33.8 0.6 3.2 4 1 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EAU91663.2 - 3.9e-05 23.9 0.0 0.0001 22.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.6 EAU91663.2 - 0.22 11.4 1.1 0.52 10.3 0.2 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 FLILHELTA PF10306.9 EAU91664.2 - 1.3e-07 31.9 0.0 2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EAU91664.2 - 0.004 17.7 0.0 0.0066 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L35Ae PF01247.18 EAU91666.1 - 2.3e-45 152.7 0.4 2.6e-45 152.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EAU91666.1 - 0.0041 17.3 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Acyl-CoA_dh_N PF02771.16 EAU91667.1 - 1.4e-29 103.1 0.0 2.4e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EAU91667.1 - 1.9e-25 89.8 0.4 6.3e-25 88.1 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EAU91667.1 - 4.5e-21 74.9 0.0 9.3e-21 73.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EAU91667.1 - 0.00014 22.1 1.3 0.00028 21.2 0.1 2.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain bZIP_1 PF00170.21 EAU91668.2 - 3e-05 24.0 4.2 5.8e-05 23.1 4.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EAU91668.2 - 0.0095 16.0 5.1 0.017 15.2 5.1 1.3 1 0 0 1 1 1 1 Basic region leucine zipper TSC22 PF01166.18 EAU91668.2 - 0.017 15.4 1.0 0.029 14.7 0.3 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family RasGAP_C PF03836.15 EAU91668.2 - 0.075 13.2 0.2 0.093 12.9 0.2 1.2 1 0 0 1 1 1 0 RasGAP C-terminus DNA_pol_B_palm PF14792.6 EAU91669.2 - 5.8e-18 65.2 0.1 9.3e-17 61.3 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EAU91669.2 - 4.8e-08 33.1 0.0 9.9e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EAU91669.2 - 2.3e-07 30.5 0.0 4.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT_2 PF16589.5 EAU91669.2 - 0.00087 19.7 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain AHJR-like PF18743.1 EAU91669.2 - 0.04 13.5 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 REase_AHJR-like Cdd1 PF11731.8 EAU91669.2 - 0.086 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus CTP_transf_like PF01467.26 EAU91670.2 - 3.1e-23 82.6 0.0 4.2e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like MFS_1 PF07690.16 EAU91671.2 - 0.0065 15.4 4.7 0.0065 15.4 4.7 2.2 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_1 PF07690.16 EAU91672.2 - 4.7e-37 127.7 20.3 7.1e-37 127.1 20.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 EAU91672.2 - 0.21 10.8 12.8 0.036 13.3 4.7 2.5 2 1 0 2 2 2 0 Sporulation factor SpoIIGA bZIP_1 PF00170.21 EAU91673.2 - 0.0088 16.1 10.9 0.0088 16.1 10.9 2.3 1 1 1 2 2 2 1 bZIP transcription factor Phage_GPO PF05929.11 EAU91673.2 - 0.18 11.4 2.3 0.27 10.8 2.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1690 PF07956.11 EAU91673.2 - 2.2 8.7 7.3 3.8 7.9 7.3 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) bZIP_2 PF07716.15 EAU91673.2 - 7.1 6.8 19.7 1.6 8.8 10.6 2.7 2 1 0 2 2 2 0 Basic region leucine zipper Melittin PF01372.17 EAU91688.2 - 0.11 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Melittin DivIC PF04977.15 EAU91691.2 - 0.00097 18.9 0.8 0.00097 18.9 0.8 1.6 2 0 0 2 2 2 1 Septum formation initiator BLOC1S3 PF15753.5 EAU91691.2 - 0.002 18.3 0.2 0.002 18.2 0.2 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 FAM209 PF15206.6 EAU91691.2 - 0.0021 17.9 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 FAM209 family FUSC-like PF12805.7 EAU91691.2 - 0.0079 15.3 0.5 0.0096 15.0 0.5 1.1 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS Nop25 PF09805.9 EAU91691.2 - 0.013 16.0 3.3 0.019 15.5 3.3 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DivIVA PF05103.13 EAU91691.2 - 0.035 14.2 0.8 0.035 14.2 0.8 2.0 1 1 1 2 2 2 0 DivIVA protein DUF1664 PF07889.12 EAU91691.2 - 0.051 13.6 0.4 0.07 13.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Kri1 PF05178.12 EAU91691.2 - 0.085 13.4 4.5 0.33 11.5 4.5 1.8 1 1 0 1 1 1 0 KRI1-like family FUSC PF04632.12 EAU91691.2 - 0.092 11.3 0.1 0.098 11.2 0.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 EAU91691.2 - 0.24 12.0 3.5 0.48 11.1 3.4 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF883 PF05957.13 EAU91691.2 - 0.42 11.3 6.5 0.76 10.4 3.9 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TBCA PF02970.16 EAU91691.2 - 0.86 10.0 7.6 1.6 9.1 7.6 1.5 1 1 0 1 1 1 0 Tubulin binding cofactor A Med21 PF11221.8 EAU91691.2 - 2.2 8.5 7.1 1.4 9.2 4.9 1.7 1 1 1 2 2 2 0 Subunit 21 of Mediator complex F-box PF00646.33 EAU91692.1 - 0.044 13.7 1.7 0.088 12.7 0.3 2.2 2 0 0 2 2 2 0 F-box domain DEAD PF00270.29 EAU91695.2 - 1.4e-13 51.0 0.0 2.6e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU91695.2 - 7.9e-10 39.1 0.0 3.2e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU91695.2 - 0.00027 21.0 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EAU91697.2 - 1.2e-62 211.6 0.1 2e-62 211.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU91697.2 - 5.2e-11 42.9 0.1 1.1e-09 38.6 0.1 2.9 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU91697.2 - 3.2e-09 37.0 0.0 7.8e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 EAU91697.2 - 0.037 14.3 0.2 0.037 14.3 0.2 3.5 4 0 0 4 4 4 0 HSA Flavi_DEAD PF07652.14 EAU91697.2 - 0.083 12.9 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Flavivirus DEAD domain Pkinase PF00069.25 EAU91698.2 - 3.2e-72 243.1 0.0 3.7e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU91698.2 - 6.7e-37 127.2 0.0 8.9e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EAU91698.2 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAU91698.2 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SET PF00856.28 EAU91699.2 - 0.0026 18.2 0.0 0.0076 16.7 0.0 1.7 1 1 0 1 1 1 1 SET domain FR47 PF08445.10 EAU91701.2 - 2.7e-09 36.9 0.0 5.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EAU91701.2 - 6.8e-08 32.5 0.0 3.6e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU91701.2 - 1.2e-05 25.6 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EAU91701.2 - 0.0004 20.7 0.0 0.00087 19.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EAU91701.2 - 0.015 15.4 0.0 0.032 14.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EAU91701.2 - 0.054 13.5 0.5 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Peptidase_S8 PF00082.22 EAU91702.1 - 4.8e-34 118.0 9.4 9e-34 117.1 9.4 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAU91702.1 - 1.2e-14 54.7 0.0 2.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 3HCDH_N PF02737.18 EAU91705.2 - 2.1e-49 167.9 1.2 7.9e-49 166.0 1.2 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EAU91705.2 - 4.5e-33 113.7 0.0 8.8e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EAU91705.2 - 0.00013 22.1 0.3 0.0003 21.0 0.3 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EAU91705.2 - 0.095 12.7 0.2 0.37 10.7 0.1 2.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EAU91705.2 - 0.096 12.0 0.1 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain COesterase PF00135.28 EAU91706.1 - 7.5e-79 265.9 0.0 2.3e-68 231.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU91706.1 - 2.2e-07 31.0 0.0 5e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 EAU91706.1 - 0.023 14.2 0.1 0.044 13.3 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EAU91706.1 - 4.4 7.8 9.9 1.3 9.6 4.0 2.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.7 EAU91707.2 - 3.5e-11 42.8 1.6 9.2e-11 41.5 0.2 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 EAU91707.2 - 0.041 13.8 0.3 14 5.7 0.1 3.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EAU91708.2 - 5.5e-07 29.4 0.2 1.2e-06 28.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like TetR_C_33 PF13305.6 EAU91708.2 - 0.16 12.7 1.1 0.33 11.7 0.2 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1771 PF08590.10 EAU91709.2 - 8.2e-05 22.9 8.6 0.00017 21.9 8.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Ctr PF04145.15 EAU91709.2 - 0.32 11.6 4.8 38 4.9 4.8 2.3 1 1 0 1 1 1 0 Ctr copper transporter family SNF2_N PF00176.23 EAU91710.2 - 8.6e-61 205.6 0.1 1.4e-60 204.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 EAU91710.2 - 4.3e-24 84.8 0.2 1.6e-23 82.9 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 EAU91710.2 - 8e-19 67.3 2.1 2.1e-11 43.5 0.1 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EAU91710.2 - 8.9e-19 67.9 0.0 2.4e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 EAU91710.2 - 4.5e-09 36.7 0.4 4.5e-09 36.7 0.4 3.3 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 HDA2-3 PF11496.8 EAU91710.2 - 1.8e-07 30.6 0.3 4.6e-07 29.3 0.3 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EAU91710.2 - 2.7e-07 30.8 0.0 8.7e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 EAU91710.2 - 2.3e-05 25.0 2.9 3.5e-05 24.4 0.5 2.6 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 Tfb4 PF03850.14 EAU91711.2 - 1.5e-50 172.2 0.0 1.9e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Olduvai PF06758.13 EAU91711.2 - 0.0067 16.7 0.0 0.27 11.5 0.0 2.7 2 0 0 2 2 2 1 Olduvai domain Asparaginase_2 PF01112.18 EAU91712.2 - 5.2e-54 183.4 0.4 7.1e-54 182.9 0.4 1.1 1 0 0 1 1 1 1 Asparaginase IF-2B PF01008.17 EAU91713.2 - 7.6e-54 182.8 0.0 1e-53 182.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Abhydrolase_3 PF07859.13 EAU91714.1 - 8.2e-30 104.2 0.0 1.7e-21 77.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU91714.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase PspC PF04024.12 EAU91714.1 - 0.21 11.4 0.4 0.51 10.2 0.4 1.6 1 0 0 1 1 1 0 PspC domain zf-C2H2 PF00096.26 EAU91715.2 - 0.00056 20.2 18.0 0.0027 18.1 0.3 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU91715.2 - 0.0022 18.3 0.4 0.0022 18.3 0.4 4.1 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EAU91715.2 - 0.0077 16.2 0.2 0.0077 16.2 0.2 2.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EAU91715.2 - 0.016 16.0 11.4 0.06 14.2 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2894 PF11445.8 EAU91715.2 - 0.017 15.6 10.6 0.017 15.6 10.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) zf-C2H2_2 PF12756.7 EAU91715.2 - 0.23 11.8 2.3 0.52 10.7 2.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 EAU91715.2 - 0.28 11.2 2.9 0.62 10.1 2.9 1.6 1 0 0 1 1 1 0 BED zinc finger zf-met PF12874.7 EAU91715.2 - 1.5 9.3 0.0 1.5 9.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MRNIP PF15749.5 EAU91715.2 - 3.6 8.3 14.2 7.4 7.3 14.2 1.4 1 0 0 1 1 1 0 MRN-interacting protein Rtf2 PF04641.12 EAU91715.2 - 6.2 6.1 15.3 35 3.6 15.3 1.9 1 1 0 1 1 1 0 Rtf2 RING-finger TPR_1 PF00515.28 EAU91716.1 - 4.9e-22 76.8 6.4 4.4e-06 26.3 0.2 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EAU91716.1 - 3.1e-18 64.4 10.3 0.00027 20.8 0.3 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EAU91716.1 - 8.2e-15 53.7 3.1 0.015 15.5 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAU91716.1 - 5.8e-14 51.5 6.8 3.1e-05 23.6 0.8 4.8 4 1 1 5 5 5 4 TPR repeat TPR_14 PF13428.6 EAU91716.1 - 1.4e-12 47.3 9.5 0.001 19.7 0.0 6.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAU91716.1 - 4.8e-12 45.4 15.0 0.012 16.0 0.6 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EAU91716.1 - 2.9e-10 40.3 10.2 3.5e-05 24.0 0.9 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EAU91716.1 - 8.9e-10 38.9 17.7 5.3e-07 30.1 1.3 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU91716.1 - 4.7e-08 33.5 10.8 0.00014 22.4 0.2 4.3 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EAU91716.1 - 1.3e-06 28.4 4.5 0.05 13.8 0.2 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU91716.1 - 4.3e-05 23.7 2.4 0.0019 18.4 0.8 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EAU91716.1 - 0.00046 20.5 9.5 1.5 9.2 0.1 4.8 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAU91716.1 - 0.0024 17.8 8.8 1.5 9.0 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAU91716.1 - 0.0039 17.0 13.3 0.84 9.6 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAU91716.1 - 0.12 12.4 2.0 2.7 8.1 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EAU91716.1 - 0.21 12.3 4.9 83 4.1 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EAU91716.1 - 0.44 10.6 5.3 2.3 8.4 0.1 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Tim17 PF02466.19 EAU91717.1 - 4.9e-31 107.4 7.5 6.6e-31 107.0 7.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-4CXXC_R1 PF10497.9 EAU91718.2 - 0.00011 22.3 3.1 0.00027 21.1 3.1 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF1699 PF08004.11 EAU91718.2 - 0.081 12.6 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) UPF0020 PF01170.18 EAU91719.1 - 8.9e-09 35.3 0.0 8.2e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EAU91719.1 - 0.0028 17.4 0.0 2.9 7.5 0.0 2.6 2 1 0 2 2 2 2 DNA methylase zf-MYND PF01753.18 EAU91720.1 - 0.3 11.2 4.1 0.14 12.3 1.7 1.7 2 0 0 2 2 2 0 MYND finger zf-MYND PF01753.18 EAU91721.2 - 5.2e-06 26.5 10.2 5.2e-06 26.5 10.2 1.8 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.18 EAU91722.2 - 1.7e-09 37.6 17.0 3.7e-09 36.5 17.0 1.6 1 0 0 1 1 1 1 MYND finger SWIM PF04434.17 EAU91724.1 - 8.8e-07 28.5 0.8 1.5e-06 27.7 0.8 1.5 1 0 0 1 1 1 1 SWIM zinc finger MFS_1 PF07690.16 EAU91725.1 - 1.1e-17 64.1 34.0 1.6e-17 63.4 34.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EAU91725.1 - 0.72 8.1 3.3 3.1 6.0 0.1 2.5 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-U1 PF06220.12 EAU91726.1 - 2.2e-10 40.1 3.2 3.3e-10 39.6 3.2 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-TRM13_CCCH PF11722.8 EAU91726.1 - 0.26 11.1 4.4 0.63 9.9 4.4 1.7 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein Chitin_synth_1 PF01644.17 EAU91728.1 - 4.2e-75 251.2 0.1 6.5e-75 250.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EAU91728.1 - 6.4e-27 93.3 0.1 1.8e-26 91.9 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EAU91728.1 - 1.9e-23 82.9 4.4 2.1e-16 59.7 0.0 2.2 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAU91728.1 - 2.6e-06 27.5 5.8 1.9e-05 24.6 5.8 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAU91728.1 - 0.018 15.0 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 MDM31_MDM32 PF08118.11 EAU91730.2 - 2.1e-219 729.6 0.0 2.5e-219 729.3 0.0 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins UCR_Fe-S_N PF10399.9 EAU91730.2 - 0.028 13.8 3.6 1.2 8.5 0.0 3.0 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LIM PF00412.22 EAU91731.1 - 0.0038 17.4 1.1 0.0057 16.8 1.1 1.3 1 0 0 1 1 1 1 LIM domain BAR PF03114.18 EAU91733.2 - 3e-50 171.1 0.4 3.5e-50 170.9 0.4 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 EAU91733.2 - 0.00053 19.6 1.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 Arfaptin-like domain SYF2 PF08231.12 EAU91733.2 - 0.071 13.5 1.6 0.16 12.4 1.6 1.7 1 1 1 2 2 2 0 SYF2 splicing factor LPD39 PF18858.1 EAU91733.2 - 0.12 12.5 2.2 3.1 7.8 0.2 2.6 3 0 0 3 3 3 0 Large polyvalent protein associated domain 39 HD_3 PF13023.6 EAU91733.2 - 0.14 12.1 1.3 4.1 7.3 0.1 2.2 2 0 0 2 2 2 0 HD domain F-box-like PF12937.7 EAU91734.1 - 0.00036 20.4 1.7 0.0015 18.4 1.7 2.2 1 0 0 1 1 1 1 F-box-like PDEase_II PF02112.15 EAU91734.1 - 0.15 11.1 0.0 15 4.5 0.0 2.2 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II AAA PF00004.29 EAU91735.2 - 1.3e-14 54.7 0.0 3.1e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 EAU91735.2 - 4.9e-11 42.5 0.0 2e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 BAH domain AAA_16 PF13191.6 EAU91735.2 - 1e-10 42.2 0.1 1.5e-09 38.4 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU91735.2 - 3.4e-07 30.6 0.0 6.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU91735.2 - 0.00023 21.5 0.0 0.00052 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 EAU91735.2 - 0.00037 20.6 0.2 0.00094 19.3 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 EAU91735.2 - 0.0089 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EAU91735.2 - 0.023 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain YL1 PF05764.13 EAU91735.2 - 0.069 13.3 25.2 0.31 11.1 19.7 2.3 2 0 0 2 2 2 0 YL1 nuclear protein NTPase_1 PF03266.15 EAU91735.2 - 0.085 12.8 0.1 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.6 EAU91735.2 - 0.1 12.8 0.1 1.8 8.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain Apt1 PF10351.9 EAU91735.2 - 0.16 10.8 1.5 0.25 10.2 1.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_11 PF13086.6 EAU91735.2 - 0.28 10.9 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Acyl-CoA_dh_2 PF08028.11 EAU91735.2 - 0.41 10.9 2.6 0.55 10.5 0.8 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Mlp PF03304.13 EAU91738.2 - 0.011 15.9 7.7 0.021 15.0 7.7 1.4 1 0 0 1 1 1 0 Mlp lipoprotein family AAA_23 PF13476.6 EAU91738.2 - 5.4 7.5 13.8 11 6.5 13.8 1.4 1 0 0 1 1 1 0 AAA domain BTB PF00651.31 EAU91739.2 - 5.1e-08 33.1 0.0 9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.7 EAU91740.1 - 7.1e-07 29.0 0.2 1.8e-06 27.7 0.2 1.7 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 EAU91741.2 - 4.4e-06 26.5 0.1 1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like Sacchrp_dh_NADP PF03435.18 EAU91742.1 - 8.4e-15 55.2 0.0 1.4e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EAU91742.1 - 1.3e-07 31.7 0.0 2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAU91742.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EAU91742.1 - 2e-05 24.6 0.1 2e-05 24.6 0.1 1.9 3 0 0 3 3 3 1 KR domain NmrA PF05368.13 EAU91742.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EAU91742.1 - 0.0037 16.7 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EAU91742.1 - 0.0059 15.7 0.0 0.013 14.5 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EAU91742.1 - 0.019 15.4 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sld7_C PF18596.1 EAU91744.2 - 8.8e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 Sld7 C-terminal domain BTB PF00651.31 EAU91745.2 - 6.9e-06 26.3 0.1 1.2e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EAU91746.2 - 0.00032 20.9 0.2 0.00057 20.1 0.2 1.3 1 0 0 1 1 1 1 BTB/POZ domain SET PF00856.28 EAU91747.1 - 2.5e-13 50.8 0.2 2.4e-12 47.5 0.2 2.2 1 1 0 1 1 1 1 SET domain Glyco_hydro_31 PF01055.26 EAU91748.1 - 6.3e-135 450.8 3.7 8.4e-135 450.4 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EAU91748.1 - 3.6e-16 59.2 1.1 1.4e-15 57.3 0.1 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 EAU91748.1 - 3.4e-06 27.3 0.0 1.1e-05 25.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gb3_synth PF04572.12 EAU91748.1 - 0.042 14.0 0.6 0.091 12.9 0.6 1.5 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Prot_ATP_OB_N PF17758.1 EAU91748.1 - 0.16 11.6 0.1 0.5 10.1 0.1 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain F-box-like PF12937.7 EAU91749.2 - 2.8e-07 30.3 0.5 6.5e-07 29.1 0.5 1.7 1 0 0 1 1 1 1 F-box-like EssA PF10661.9 EAU91752.2 - 0.38 10.6 5.3 0.85 9.5 5.3 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA AMP-binding PF00501.28 EAU91754.2 - 2.4e-39 135.1 0.1 1.2e-31 109.8 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 EAU91754.2 - 3e-05 23.9 0.0 8e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EAU91754.2 - 0.0054 17.7 0.0 0.012 16.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2957 PF11170.8 EAU91754.2 - 0.032 13.1 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) RHD3 PF05879.12 EAU91755.1 - 9e-255 847.4 7.2 3.3e-254 845.5 7.2 1.7 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EAU91755.1 - 2.6e-06 27.5 0.0 6.9e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 EAU91755.1 - 4.1e-06 26.2 0.2 7.5e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EAU91755.1 - 1.5e-05 25.1 0.2 4.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 EAU91755.1 - 0.0028 17.9 0.6 0.0065 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EAU91755.1 - 0.12 12.7 0.0 0.4 10.9 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SKA1 PF07160.12 EAU91756.1 - 0.17 11.7 0.0 0.59 9.9 0.0 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1600 PF07667.11 EAU91756.1 - 0.26 11.5 0.9 0.69 10.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) Helicase_C PF00271.31 EAU91758.2 - 4.3e-09 36.7 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU91758.2 - 7.3e-09 35.6 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase F-box-like PF12937.7 EAU91760.2 - 0.0092 15.9 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like SHS2_Rpb7-N PF03876.17 EAU91761.1 - 1e-14 54.6 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EAU91761.1 - 1.2e-11 44.8 0.4 2.4e-11 43.8 0.4 1.5 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EAU91761.1 - 0.0082 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 EHN PF06441.12 EAU91762.2 - 7.1e-31 106.8 0.7 1.6e-30 105.6 0.7 1.6 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EAU91762.2 - 1.1e-05 25.2 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 EAU91762.2 - 0.2 10.3 0.0 1.2 7.8 0.0 1.9 2 0 0 2 2 2 0 Ndr family MMS1_N PF10433.9 EAU91763.2 - 2.9e-136 455.0 0.0 4.6e-136 454.3 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EAU91763.2 - 8.5e-92 307.9 0.0 8.4e-91 304.6 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region Slu7 PF11708.8 EAU91764.1 - 8e-111 370.1 15.2 8e-111 370.1 15.2 2.4 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EAU91764.1 - 0.055 13.2 0.4 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EAU91764.1 - 0.76 10.0 3.1 1.4 9.2 3.1 1.4 1 0 0 1 1 1 0 Zinc knuckle OCRE PF17780.1 EAU91764.1 - 3.2 7.8 8.2 2.8 8.1 0.5 3.3 3 0 0 3 3 3 0 OCRE domain UDPGP PF01704.18 EAU91766.1 - 1.7e-199 662.7 0.3 1.9e-199 662.5 0.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ERO1 PF04137.15 EAU91768.2 - 3.4e-127 424.5 0.0 4e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ATP-sulfurylase PF01747.17 EAU91769.1 - 4.5e-88 294.2 0.1 8e-88 293.4 0.1 1.4 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EAU91769.1 - 3.5e-53 179.7 0.0 5.3e-53 179.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EAU91769.1 - 5.9e-53 178.8 0.0 1e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.12 EAU91769.1 - 0.1 12.4 0.0 0.62 9.9 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CTP_transf_like PF01467.26 EAU91769.1 - 0.16 12.1 0.0 1.4 9.1 0.0 2.5 3 1 0 3 3 3 0 Cytidylyltransferase-like KTI12 PF08433.10 EAU91769.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNase_H2-Ydr279 PF09468.10 EAU91771.2 - 5.3e-16 59.2 0.0 8.6e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EAU91771.2 - 2.8e-12 46.7 0.0 1.2e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain CBM_1 PF00734.18 EAU91773.2 - 4.3e-13 49.0 14.0 4.3e-13 49.0 14.0 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EAU91773.2 - 0.0038 17.4 3.2 0.0039 17.4 2.0 1.6 2 0 0 2 2 2 1 Toxin 7 SKN1 PF03935.15 EAU91774.2 - 1.2e-130 436.3 4.4 7.6e-72 242.3 0.8 2.7 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Mg_trans_NIPA PF05653.14 EAU91775.2 - 2.7e-16 59.5 14.7 3e-09 36.4 3.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EAU91775.2 - 1.4e-05 25.3 25.7 1.7e-05 25.0 5.4 3.1 3 1 0 3 3 3 2 EamA-like transporter family Ssl1 PF04056.14 EAU91776.2 - 6.9e-60 202.2 0.1 3.4e-59 199.9 0.0 2.0 2 1 0 2 2 2 1 Ssl1-like VWA_2 PF13519.6 EAU91776.2 - 1.2e-11 45.1 0.0 2.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EAU91776.2 - 7.1e-05 23.1 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EAU91776.2 - 0.29 10.6 6.7 7.7 5.9 6.4 2.3 2 0 0 2 2 2 0 Transcription factor Tfb4 Rx_N PF18052.1 EAU91777.2 - 0.39 11.0 1.4 18 5.7 0.0 3.1 4 0 0 4 4 4 0 Rx N-terminal domain Rad10 PF03834.14 EAU91778.2 - 8.5e-44 148.2 0.0 1.3e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EAU91778.2 - 6.7e-06 26.6 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EAU91778.2 - 0.0045 17.1 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif ABC_tran PF00005.27 EAU91779.2 - 1.1e-17 64.8 0.0 6.6e-09 36.4 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EAU91779.2 - 0.012 15.4 0.0 16 5.2 0.0 3.3 2 2 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Amidohydro_3 PF07969.11 EAU91780.1 - 9e-12 45.2 0.2 7e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EAU91780.1 - 1e-10 41.5 0.0 1.3e-07 31.3 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Tetraspanin PF00335.20 EAU91782.1 - 0.00022 21.0 11.2 0.00022 21.0 11.2 2.1 1 1 1 2 2 2 1 Tetraspanin family YrhC PF14143.6 EAU91782.1 - 0.43 10.7 3.5 0.33 11.1 1.2 2.0 2 0 0 2 2 2 0 YrhC-like protein DUF5418 PF17439.2 EAU91782.1 - 6.9 6.7 8.5 13 5.9 8.5 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5418) PAM2 PF07145.15 EAU91783.2 - 0.019 14.7 1.1 0.019 14.7 1.1 2.5 3 0 0 3 3 3 0 Ataxin-2 C-terminal region DUF1746 PF08508.10 EAU91784.2 - 1.3e-10 41.6 2.7 2.8e-10 40.5 2.7 1.6 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) CX9C PF16860.5 EAU91785.1 - 0.00043 20.2 0.3 0.54 10.3 0.1 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 EAU91785.1 - 0.0016 18.6 1.6 0.0085 16.3 1.6 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 EAU91785.1 - 0.019 15.0 0.7 0.068 13.2 0.1 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Oxygenase-NA PF09859.9 EAU91786.1 - 0.09 12.3 0.0 12 5.4 0.0 2.5 2 0 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA FtsX PF02687.21 EAU91786.1 - 1.8 9.1 4.7 2.3 8.8 2.8 2.1 2 0 0 2 2 2 0 FtsX-like permease family Fungal_trans PF04082.18 EAU91787.2 - 6.2e-19 68.1 0.0 1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 EAU91787.2 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF1674 PF07896.12 EAU91788.1 - 8.4e-13 48.6 12.7 2.4e-12 47.1 12.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) CagY_I PF14585.6 EAU91788.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 CagY type 1 repeat LSM PF01423.22 EAU91789.1 - 1.1e-14 53.9 0.2 1.4e-14 53.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 EAU91789.1 - 0.015 15.3 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain E3_binding PF02817.17 EAU91789.1 - 0.031 14.6 0.1 0.064 13.6 0.1 1.5 1 0 0 1 1 1 0 e3 binding domain SM-ATX PF14438.6 EAU91789.1 - 0.041 14.0 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain TPR_1 PF00515.28 EAU91791.2 - 2e-29 100.1 16.3 8.7e-05 22.2 0.0 7.2 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EAU91791.2 - 5e-23 79.3 11.2 8.6e-06 25.6 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat ANAPC8 PF04049.13 EAU91791.2 - 2.1e-22 79.7 0.0 6.5e-22 78.1 0.0 1.8 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 EAU91791.2 - 3.6e-21 74.1 12.4 0.0063 17.2 0.1 7.4 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EAU91791.2 - 6.7e-21 72.7 21.1 0.0014 18.6 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EAU91791.2 - 3.3e-15 56.1 20.6 0.0021 18.3 1.0 6.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EAU91791.2 - 9.9e-13 47.6 5.8 2.9e-07 30.1 0.8 5.0 2 2 2 4 4 4 2 TPR repeat TPR_16 PF13432.6 EAU91791.2 - 2e-12 47.5 13.6 1.1e-05 26.0 1.7 6.4 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EAU91791.2 - 1.8e-10 40.1 18.8 0.014 15.4 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EAU91791.2 - 1.7e-08 34.8 7.9 0.056 13.9 0.1 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAU91791.2 - 2.7e-08 33.6 5.8 0.44 11.1 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EAU91791.2 - 2e-07 31.1 9.0 0.006 16.7 0.4 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EAU91791.2 - 0.00047 20.6 15.1 8.8 7.2 0.0 7.7 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.10 EAU91791.2 - 0.00095 18.3 0.6 0.3 10.0 0.0 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 EAU91791.2 - 0.0012 18.1 5.0 0.051 12.8 3.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU91791.2 - 0.0014 18.8 22.2 0.39 11.0 0.6 6.2 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 EAU91791.2 - 0.0037 17.5 0.9 1.5 9.0 0.0 3.5 3 1 0 3 3 3 1 Tetratrico peptide repeat SNAP PF14938.6 EAU91791.2 - 0.033 13.6 3.8 2.4 7.5 0.0 3.2 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP DUF3856 PF12968.7 EAU91791.2 - 0.044 13.8 1.4 0.82 9.7 0.0 3.2 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) FAT PF02259.23 EAU91791.2 - 0.091 12.0 3.5 1.6 7.8 1.6 3.0 3 1 0 3 3 3 0 FAT domain TPR_10 PF13374.6 EAU91791.2 - 0.37 10.7 22.1 0.99 9.4 0.2 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat Alg14 PF08660.11 EAU91792.2 - 4.4e-48 163.5 0.0 5.6e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF4131 PF13567.6 EAU91792.2 - 0.21 11.2 2.4 0.18 11.4 0.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4118 PF13493.6 EAU91792.2 - 0.48 10.2 6.1 0.62 9.9 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) zf-CCCH PF00642.24 EAU91793.1 - 2.6e-14 52.7 16.0 3.8e-07 29.9 2.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EAU91793.1 - 0.00065 20.4 1.7 0.83 10.4 0.1 2.3 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 EAU91793.1 - 0.0065 16.5 3.3 0.0065 16.5 3.3 2.6 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 EAU91793.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_3 PF15663.5 EAU91793.1 - 0.028 14.6 4.6 0.18 12.0 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger containing family Peptidase_S8 PF00082.22 EAU91794.1 - 1.1e-28 100.4 20.2 3.3e-28 98.8 20.2 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EAU91794.1 - 2.7e-06 28.0 0.0 3.2e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 Mito_carr PF00153.27 EAU91795.1 - 6.6e-17 61.2 0.0 1.1e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein SNF2_N PF00176.23 EAU91796.2 - 1.5e-38 132.4 0.2 3.6e-32 111.4 0.1 2.9 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU91796.2 - 5.8e-19 68.5 0.1 3.4e-18 66.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU91796.2 - 5.5e-10 39.5 0.0 3.8e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SBP_bac_5 PF00496.22 EAU91796.2 - 0.029 13.3 0.4 0.06 12.3 0.1 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle Sybindin PF04099.12 EAU91797.2 - 7.1e-17 61.7 0.0 8.3e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EAU91797.2 - 0.05 13.7 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Yip1 PF04893.17 EAU91799.1 - 2e-06 27.6 15.0 3.1e-06 27.0 15.0 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1168 PF06658.12 EAU91800.1 - 5.9e-39 133.0 15.7 7.6e-39 132.6 15.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) PPL5 PF18168.1 EAU91800.1 - 0.02 14.2 5.2 0.027 13.8 5.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Viral_P18 PF04521.13 EAU91800.1 - 0.11 12.3 1.2 0.17 11.6 1.2 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF778 PF05608.12 EAU91800.1 - 0.2 12.0 1.0 0.25 11.7 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Hid1 PF12722.7 EAU91800.1 - 1.6 6.8 4.3 2.1 6.4 4.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 EAU91800.1 - 2.5 7.8 9.4 3.1 7.5 9.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EAU91800.1 - 6 5.5 6.2 7.7 5.2 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PseudoU_synth_2 PF00849.22 EAU91801.1 - 6e-26 91.4 0.0 1.3e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase ThiS PF02597.20 EAU91801.1 - 0.19 12.4 0.0 0.4 11.3 0.0 1.5 1 0 0 1 1 1 0 ThiS family Cwf_Cwc_15 PF04889.12 EAU91802.2 - 1.2e-79 267.6 28.3 1.4e-79 267.4 28.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EAU91802.2 - 0.0022 16.3 24.4 0.0025 16.1 24.4 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EAU91802.2 - 0.096 12.1 29.7 0.12 11.7 29.7 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EAU91802.2 - 0.11 10.8 20.2 0.12 10.6 20.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EAU91802.2 - 0.85 8.5 7.6 1.1 8.2 7.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sin_N PF04801.13 EAU91802.2 - 1.4 8.1 12.3 2.3 7.3 12.3 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region SAPS PF04499.15 EAU91802.2 - 1.6 7.5 11.9 1.9 7.2 11.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.11 EAU91802.2 - 8.9 4.3 11.1 13 3.8 11.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FCH PF00611.23 EAU91803.1 - 5.8e-13 48.9 0.0 1.5e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EAU91803.1 - 1e-10 41.1 0.3 1.9e-10 40.2 0.3 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU91803.1 - 3.5e-09 36.4 0.1 7e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU91803.1 - 9.3e-06 25.2 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain VGCC_beta4Aa_N PF12052.8 EAU91803.1 - 2.5 8.3 5.5 0.49 10.5 1.0 2.2 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF4407 PF14362.6 EAU91803.1 - 8.2 5.7 8.3 12 5.1 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IKI3 PF04762.12 EAU91804.2 - 7.5e-246 818.5 0.0 2.4e-187 624.9 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 EAU91804.2 - 0.00027 21.2 0.1 6.2 7.2 0.0 5.1 6 0 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_16 PF13432.6 EAU91804.2 - 0.023 15.4 0.5 0.23 12.1 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Efg1 PF10153.9 EAU91805.1 - 1.5e-35 121.9 14.1 1.5e-35 121.9 14.1 2.1 3 0 0 3 3 3 1 rRNA-processing protein Efg1 TetR_C_2 PF08361.11 EAU91805.1 - 0.13 12.4 2.7 2.7 8.1 0.7 2.2 1 1 1 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region FUSC PF04632.12 EAU91807.2 - 1.7 7.1 5.1 2.2 6.7 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PIF1 PF05970.14 EAU91812.2 - 2.2e-26 92.9 0.1 2.4e-23 82.9 0.0 2.5 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAU91812.2 - 3.6e-13 49.7 0.0 1.4e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU91812.2 - 3.3e-06 27.5 0.0 8.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU91812.2 - 0.022 15.2 0.1 0.068 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Cut8 PF08559.10 EAU91814.1 - 0.066 12.8 1.7 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Cut8, nuclear proteasome tether protein Herpes_DNAp_acc PF04929.12 EAU91814.1 - 0.27 10.2 7.8 0.43 9.5 7.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hamartin PF04388.12 EAU91814.1 - 2.5 6.7 5.5 2.7 6.5 5.5 1.1 1 0 0 1 1 1 0 Hamartin protein OmpH PF03938.14 EAU91816.2 - 0.0015 18.8 7.2 0.0015 18.8 7.2 2.4 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 EAU91816.2 - 0.0028 17.7 12.4 0.0028 17.7 12.4 2.7 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EAU91816.2 - 0.016 15.3 12.6 0.016 15.3 12.6 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding KfrA_N PF11740.8 EAU91816.2 - 0.018 15.7 2.1 0.018 15.7 2.1 3.9 2 1 2 4 4 4 0 Plasmid replication region DNA-binding N-term SPATA1_C PF15743.5 EAU91816.2 - 0.065 13.3 9.5 0.16 12.1 9.5 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus FapA PF03961.13 EAU91816.2 - 0.18 10.4 3.7 0.3 9.6 3.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ASL_C PF08328.11 EAU91816.2 - 0.19 11.8 2.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal CCDC144C PF14915.6 EAU91816.2 - 0.23 10.6 18.2 0.28 10.3 15.5 2.3 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region DUF4200 PF13863.6 EAU91816.2 - 0.86 10.0 15.3 0.027 14.8 7.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_F PF12259.8 EAU91816.2 - 2.3 6.6 4.7 3.4 6.1 4.7 1.1 1 0 0 1 1 1 0 Baculovirus F protein CorA PF01544.18 EAU91816.2 - 7.8 5.7 6.0 15 4.8 6.0 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein KxDL PF10241.9 EAU91817.2 - 0.07 13.4 1.4 0.39 11.0 1.1 2.5 1 1 0 1 1 1 0 Uncharacterized conserved protein KASH_CCD PF14662.6 EAU91817.2 - 1.6 8.5 11.5 1.1 9.1 9.2 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Phlebovirus_NSM PF07246.11 EAU91817.2 - 1.8 7.9 5.1 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Hydantoinase_A PF01968.18 EAU91818.1 - 0.012 14.9 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Peptidase_M22 PF00814.25 EAU91818.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family HSP70 PF00012.20 EAU91819.2 - 0.015 13.5 0.1 0.029 12.6 0.1 1.4 1 1 0 1 1 1 0 Hsp70 protein Peptidase_M22 PF00814.25 EAU91819.2 - 0.034 13.8 0.0 0.074 12.7 0.0 1.6 1 1 0 1 1 1 0 Glycoprotease family StbA PF06406.11 EAU91819.2 - 0.082 12.1 0.1 0.4 9.9 0.0 2.0 1 1 0 2 2 2 0 StbA protein DDR PF08841.10 EAU91819.2 - 0.11 11.5 0.0 4.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain HSP70 PF00012.20 EAU91820.1 - 0.00012 20.4 0.0 0.00018 19.8 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.11 EAU91820.1 - 0.024 13.9 0.0 0.059 12.6 0.0 1.5 1 1 0 1 1 1 0 StbA protein CBM53 PF16760.5 EAU91820.1 - 0.1 13.2 0.0 0.63 10.7 0.0 2.3 2 0 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) RNA_pol_A_bac PF01000.26 EAU91821.2 - 3.8e-23 82.0 0.0 6.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EAU91821.2 - 1.3e-11 43.7 0.0 2.1e-11 43.1 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M28 PF04389.17 EAU91824.2 - 8.3e-27 94.2 0.0 1.5e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 AF-4 PF05110.13 EAU91824.2 - 0.021 12.9 8.3 0.029 12.5 8.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 EAU91824.2 - 0.029 14.0 15.2 0.045 13.4 15.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1180 PF06679.12 EAU91824.2 - 0.092 13.2 2.1 0.54 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Peptidase_M42 PF05343.14 EAU91824.2 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DUF3446 PF11928.8 EAU91824.2 - 0.71 10.2 10.4 1.7 9.0 5.9 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain IMUP PF15761.5 EAU91824.2 - 1.2 9.9 14.1 0.14 12.8 9.6 1.7 2 0 0 2 2 2 0 Immortalisation up-regulated protein Rrn6 PF10214.9 EAU91824.2 - 5.8 5.3 8.0 8.2 4.8 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4131 PF13567.6 EAU91824.2 - 7.7 6.1 11.0 4.7 6.8 2.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MAGE_N PF12440.8 EAU91825.1 - 0.27 11.9 12.0 0.36 11.6 12.0 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Phage_GP20 PF06810.11 EAU91826.2 - 0.0038 17.0 0.2 0.008 16.0 0.2 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 NPV_P10 PF05531.12 EAU91826.2 - 0.01 16.3 0.7 0.021 15.3 0.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2944 PF11161.8 EAU91827.1 - 0.093 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Sugar_tr PF00083.24 EAU91829.2 - 2e-73 247.8 23.4 1.1e-69 235.5 7.4 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EAU91829.2 - 2.6e-25 89.1 29.2 3.5e-24 85.4 21.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EAU91829.2 - 0.0057 15.0 3.1 0.66 8.2 0.4 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 EAU91829.2 - 0.011 14.1 2.0 0.018 13.5 2.0 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EAU91829.2 - 0.036 12.9 0.1 0.036 12.9 0.1 2.6 2 2 0 2 2 2 0 MFS_1 like family WD40 PF00400.32 EAU91830.2 - 3e-17 62.7 19.4 0.00013 22.7 0.0 6.7 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU91830.2 - 4e-14 52.7 3.3 1.7e-05 25.1 0.2 4.3 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAU91830.2 - 3.4e-06 27.1 0.7 0.0082 16.0 0.3 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A SARA PF11409.8 EAU91831.2 - 0.42 10.8 5.2 4.1 7.7 2.5 2.9 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) Pinin_SDK_memA PF04696.13 EAU91835.1 - 1.2e-09 38.3 7.4 1.2e-09 38.3 7.4 3.3 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region MFS_1 PF07690.16 EAU91836.2 - 1.5e-10 40.6 43.0 3.5e-10 39.3 43.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRIQK PF15168.6 EAU91836.2 - 0.23 11.4 3.0 0.89 9.5 3.0 2.0 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family Cellulase PF00150.18 EAU91838.2 - 1.8e-06 27.6 0.0 2.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SARAF PF06682.12 EAU91838.2 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4714 PF15833.5 EAU91838.2 - 0.25 11.3 0.4 1.4 8.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) TEA PF01285.18 EAU91839.1 - 4.3e-23 81.2 0.0 7.6e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Dynamin_M PF01031.20 EAU91841.2 - 9.1e-27 94.0 0.0 6.1e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 EAU91841.2 - 1.6e-23 83.6 0.0 3.3e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EAU91841.2 - 9.9e-15 54.5 0.5 3.2e-12 46.4 0.0 3.2 4 0 0 4 4 4 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EAU91841.2 - 1.2e-05 25.4 0.1 8e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EAU91841.2 - 0.023 15.2 0.0 0.13 12.8 0.0 2.2 3 0 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 EAU91841.2 - 0.047 14.1 0.4 1.7 9.0 0.0 3.1 3 1 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.6 EAU91841.2 - 0.052 13.3 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EAU91841.2 - 0.085 13.1 0.1 0.81 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cut8 PF08559.10 EAU91841.2 - 0.095 12.3 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein AAA_21 PF13304.6 EAU91841.2 - 0.15 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system polyprenyl_synt PF00348.17 EAU91842.1 - 1.3e-61 207.9 0.0 1.7e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ima1_N PF09779.9 EAU91845.2 - 0.007 17.2 0.1 5 8.0 0.0 2.3 2 0 0 2 2 2 2 Ima1 N-terminal domain PHD PF00628.29 EAU91845.2 - 0.068 13.1 1.4 7.3 6.6 0.1 3.1 3 0 0 3 3 3 0 PHD-finger C1_2 PF03107.16 EAU91845.2 - 0.085 13.2 3.2 28 5.1 0.0 3.2 3 0 0 3 3 3 0 C1 domain zf-C2HCIx2C PF10782.9 EAU91845.2 - 0.21 11.5 1.3 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger zinc_ribbon_10 PF10058.9 EAU91845.2 - 0.49 10.2 3.1 6.3 6.6 0.3 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-Sec23_Sec24 PF04810.15 EAU91845.2 - 0.58 10.2 3.9 8.3 6.6 0.0 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger F-box-like PF12937.7 EAU91846.2 - 0.0025 17.7 0.3 0.0075 16.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like Pkinase_fungal PF17667.1 EAU91847.2 - 6.7e-27 94.3 0.0 1.3e-15 57.1 0.4 2.8 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EAU91847.2 - 3.3e-05 23.9 0.0 0.00023 21.2 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAU91847.2 - 0.014 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain zf-MYND PF01753.18 EAU91848.1 - 4.3e-07 29.9 15.1 7.6e-07 29.1 15.1 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU91848.1 - 0.27 11.6 11.4 0.49 10.7 11.4 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EAU91849.1 - 3.4e-07 30.3 8.5 5.4e-07 29.6 8.5 1.3 1 0 0 1 1 1 1 MYND finger RPAP2_Rtr1 PF04181.13 EAU91849.1 - 0.086 13.2 3.0 0.16 12.3 3.0 1.5 1 0 0 1 1 1 0 Rtr1/RPAP2 family Sina PF03145.16 EAU91849.1 - 0.1 12.6 0.8 0.14 12.1 0.8 1.2 1 0 0 1 1 1 0 Seven in absentia protein family DUF2222 PF09984.9 EAU91849.1 - 0.23 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) zf-C6H2 PF15801.5 EAU91849.1 - 0.4 11.0 7.9 0.69 10.3 7.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 EAU91849.1 - 5.7 6.9 9.2 18 5.3 9.2 1.8 1 1 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 EAU91850.1 - 3.2e-07 30.3 12.6 5.4e-07 29.6 12.6 1.4 1 0 0 1 1 1 1 MYND finger DRIM PF07539.12 EAU91851.2 - 1.9e-155 518.7 0.2 1.9e-155 518.7 0.2 3.8 4 1 0 4 4 4 1 Down-regulated in metastasis HEAT PF02985.22 EAU91851.2 - 0.027 14.7 5.0 15 6.2 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat CLASP_N PF12348.8 EAU91851.2 - 0.058 12.9 1.0 6.7 6.2 0.1 4.1 4 0 0 4 4 4 0 CLASP N terminal LRR_4 PF12799.7 EAU91853.1 - 1.2 9.7 8.9 78 3.9 0.5 5.1 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EAU91856.2 - 0.0033 17.3 0.4 0.0033 17.3 0.4 2.1 2 0 0 2 2 2 1 F-box-like CoA_transf_3 PF02515.17 EAU91857.2 - 1.5e-98 330.3 0.0 4.7e-98 328.7 0.0 1.7 1 1 0 1 1 1 1 CoA-transferase family III Lactonase PF10282.9 EAU91858.1 - 6.1e-52 177.0 0.0 7.3e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 EAU91858.1 - 0.17 11.0 0.0 0.66 9.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) TMEM51 PF15345.6 EAU91859.2 - 0.0048 16.8 0.2 0.97 9.2 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein 51 Herpes_gE PF02480.16 EAU91859.2 - 0.012 14.3 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PrpF PF04303.13 EAU91860.1 - 6.3e-65 219.5 1.4 2e-62 211.3 1.4 3.4 1 1 0 1 1 1 1 PrpF protein Gcn1_N PF12074.8 EAU91861.2 - 2.8e-106 355.8 0.8 2.4e-105 352.8 0.0 3.2 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EAU91861.2 - 4e-35 116.8 13.4 0.2 12.0 0.0 18.3 20 0 0 20 20 18 8 HEAT repeat HEAT_EZ PF13513.6 EAU91861.2 - 8.2e-32 109.2 19.8 0.0013 19.1 0.0 17.7 17 2 1 18 18 17 6 HEAT-like repeat HEAT_2 PF13646.6 EAU91861.2 - 3.2e-30 104.4 23.1 8.2e-05 22.9 0.0 13.4 8 3 3 12 12 12 7 HEAT repeats Cnd1 PF12717.7 EAU91861.2 - 1.4e-11 44.7 0.0 0.28 11.2 0.0 8.8 5 2 4 10 10 10 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EAU91861.2 - 4.3e-10 39.5 0.0 0.00023 20.8 0.0 5.2 4 1 1 5 5 5 2 CLASP N terminal DRIM PF07539.12 EAU91861.2 - 2.2e-06 26.3 0.8 2 6.6 0.0 6.6 5 2 2 7 7 7 1 Down-regulated in metastasis Vac14_Fab1_bd PF12755.7 EAU91861.2 - 3.3e-06 27.6 0.0 12 6.6 0.0 7.1 6 1 2 8 8 7 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EAU91861.2 - 7.6e-06 24.8 0.0 0.51 8.8 0.0 5.9 4 3 1 6 6 6 1 Adaptin N terminal region IFRD PF05004.13 EAU91861.2 - 1.9e-05 24.0 10.0 1.3 8.1 0.0 7.4 5 3 2 7 7 7 1 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 EAU91861.2 - 0.00017 21.7 1.0 21 5.2 0.0 5.8 5 2 2 7 7 7 0 Parkin co-regulated protein RIX1 PF08167.12 EAU91861.2 - 0.00062 19.6 6.1 0.05 13.3 0.1 6.3 6 1 0 7 7 7 1 rRNA processing/ribosome biogenesis DUF3437 PF11919.8 EAU91861.2 - 0.0018 18.2 0.2 2.2 8.2 0.0 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF3437) DUF4042 PF13251.6 EAU91861.2 - 0.0023 17.7 3.8 1.1 8.9 0.0 6.4 7 2 1 8 8 8 1 Domain of unknown function (DUF4042) NUC173 PF08161.12 EAU91861.2 - 0.0028 17.4 0.2 9.2 5.9 0.1 4.7 4 0 0 4 4 4 0 NUC173 domain Tti2 PF10521.9 EAU91861.2 - 0.0065 16.0 0.1 1.1 8.7 0.0 4.5 5 0 0 5 5 5 1 Tti2 family FANCI_S2 PF14676.6 EAU91861.2 - 0.021 15.1 0.3 1.9 8.8 0.2 3.3 2 1 0 2 2 2 0 FANCI solenoid 2 HEAT_PBS PF03130.16 EAU91861.2 - 0.13 13.0 8.1 11 7.0 0.4 7.6 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat BP28CT PF08146.12 EAU91861.2 - 0.15 11.9 0.1 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 BP28CT (NUC211) domain Cohesin_HEAT PF12765.7 EAU91861.2 - 0.35 11.2 3.5 11 6.4 0.1 4.1 4 0 0 4 4 3 0 HEAT repeat associated with sister chromatid cohesion DUF1400 PF07176.11 EAU91861.2 - 5.4 7.3 6.6 18 5.6 0.0 4.3 6 0 0 6 6 3 0 Alpha/beta hydrolase of unknown function (DUF1400) CTK3 PF12243.8 EAU91862.2 - 1.4e-35 122.0 0.1 1.9e-26 92.5 0.0 2.3 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EAU91862.2 - 2e-26 92.0 2.5 4.1e-26 90.9 2.5 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus DUF3323 PF11796.8 EAU91863.2 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) zf-MYND PF01753.18 EAU91866.1 - 7.5e-07 29.1 15.0 1.3e-06 28.4 15.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU91866.1 - 0.37 11.1 10.6 0.66 10.3 10.6 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 EAU91867.1 - 0.07 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 F-box-like Phage_holin_3_1 PF05106.12 EAU91867.1 - 0.24 11.8 0.3 0.6 10.6 0.3 1.6 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) tRNA-synt_2 PF00152.20 EAU91868.1 - 1.7e-90 303.3 0.0 2.7e-90 302.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAU91868.1 - 6.1e-10 39.0 0.0 1.6e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Med19 PF10278.9 EAU91868.1 - 0.03 14.3 6.8 0.058 13.3 6.8 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PASTA PF03793.19 EAU91868.1 - 0.06 13.2 0.0 0.59 10.0 0.0 2.5 2 0 0 2 2 2 0 PASTA domain Sec62 PF03839.16 EAU91868.1 - 3.2 7.2 5.5 5.7 6.4 5.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 ABC_trans_N PF14510.6 EAU91871.1 - 0.23 12.1 0.1 0.23 12.1 0.1 1.5 2 0 0 2 2 2 0 ABC-transporter N-terminal TP_methylase PF00590.20 EAU91872.1 - 4e-23 82.5 0.0 5.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases F-box-like PF12937.7 EAU91873.2 - 1.1e-07 31.6 1.3 9.8e-07 28.6 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EAU91874.1 - 6.6e-06 25.9 1.6 1.7e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 EAU91875.2 - 7e-50 167.5 0.9 1.6e-49 166.3 0.9 1.6 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.33 EAU91875.2 - 0.00029 20.6 3.1 0.00038 20.3 1.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EAU91875.2 - 0.0031 17.4 0.4 0.0031 17.4 0.4 2.8 4 0 0 4 4 4 1 F-box-like DFF-C PF09033.10 EAU91876.1 - 0.032 14.1 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Glyco_hydro_10 PF00331.20 EAU91879.1 - 2.5e-112 375.1 0.0 2.9e-112 374.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_10 PF00331.20 EAU91880.2 - 1.6e-104 349.5 0.0 1.9e-104 349.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 LSM PF01423.22 EAU91881.2 - 1.1e-16 60.2 0.0 1.7e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain Evr1_Alr PF04777.13 EAU91882.2 - 9e-28 96.7 0.6 1.5e-27 95.9 0.2 1.6 2 0 0 2 2 2 1 Erv1 / Alr family Kri1_C PF12936.7 EAU91884.1 - 1.2e-25 89.5 0.5 1.2e-25 89.5 0.5 5.9 7 0 0 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 EAU91884.1 - 3.2e-24 85.4 10.3 3.2e-24 85.4 10.3 8.0 7 2 2 9 9 9 2 KRI1-like family DUF4097 PF13349.6 EAU91888.1 - 0.047 13.0 1.1 0.092 12.1 1.1 1.5 1 0 0 1 1 1 0 Putative adhesin PRIMA1 PF16101.5 EAU91888.1 - 0.5 10.4 3.4 0.41 10.7 1.8 1.7 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_hydro_71 PF03659.14 EAU91889.2 - 3.8e-118 394.6 1.5 4.4e-118 394.4 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Abhydrolase_1 PF00561.20 EAU91890.2 - 1.5e-12 47.8 0.0 2.7e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EAU91890.2 - 1e-08 34.8 0.0 2.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU91890.2 - 0.052 14.1 0.0 0.096 13.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 EAU91890.2 - 0.056 13.1 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase YozE_SAM_like PF06855.12 EAU91890.2 - 0.082 13.1 0.2 1.7 8.9 0.1 2.8 2 0 0 2 2 2 0 YozE SAM-like fold F-box-like_2 PF13013.6 EAU91891.1 - 3.5e-11 43.0 0.6 1.1e-10 41.5 0.6 1.8 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.33 EAU91891.1 - 2.3e-07 30.5 0.0 1.5e-06 28.0 0.0 2.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU91891.1 - 0.00037 20.3 0.0 0.0015 18.4 0.0 2.1 1 0 0 1 1 1 1 F-box-like BTB PF00651.31 EAU91892.2 - 6.4e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BLM_N PF16202.5 EAU91892.2 - 0.024 13.8 4.1 0.034 13.3 4.1 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein DUF1515 PF07439.11 EAU91892.2 - 0.48 10.5 1.7 0.98 9.5 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) BTB PF00651.31 EAU91893.1 - 0.00056 20.1 0.0 0.0018 18.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain zf-MYND PF01753.18 EAU91896.1 - 9.8e-09 35.2 9.2 1.8e-08 34.3 9.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU91896.1 - 0.016 15.5 6.8 0.028 14.7 6.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding BTB PF00651.31 EAU91897.1 - 1.2e-08 35.2 0.0 1.6e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EAU91898.2 - 5.6e-12 45.9 0.0 8.6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HSP20 PF00011.21 EAU91899.1 - 8.5e-22 77.2 0.1 4.5e-21 74.9 0.0 1.8 1 1 1 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAU91899.1 - 3.2e-10 39.4 0.0 5.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 EAU91899.1 - 0.18 12.0 0.0 20 5.4 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal HSP20 PF00011.21 EAU91901.1 - 1.5e-21 76.4 0.0 1.8e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAU91901.1 - 4.9e-10 38.8 0.0 7.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EAU91901.1 - 0.11 13.6 0.0 0.37 11.8 0.0 1.8 1 1 1 2 2 2 0 CS domain TubC_N PF18563.1 EAU91901.1 - 0.12 12.4 0.0 4.4 7.4 0.0 2.1 2 0 0 2 2 2 0 TubC N-terminal docking domain F-box-like_2 PF13013.6 EAU91903.2 - 9.9e-18 64.1 1.3 1e-16 60.8 1.2 2.5 2 1 0 2 2 2 1 F-box-like domain F-box PF00646.33 EAU91903.2 - 0.00037 20.3 0.5 0.0011 18.8 0.5 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU91903.2 - 0.18 11.7 1.9 0.39 10.7 0.6 2.3 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.6 EAU91903.2 - 0.19 11.9 0.2 1.2 9.3 0.0 2.5 3 0 0 3 3 3 0 Leucine Rich repeat Rit1_C PF17184.4 EAU91904.2 - 5.3e-61 206.5 0.0 5.2e-55 186.8 0.0 2.2 1 1 1 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EAU91904.2 - 9.7e-25 87.0 0.0 2.8e-24 85.5 0.0 1.8 1 0 0 1 1 1 1 Rit1 DUSP-like domain BTB PF00651.31 EAU91905.2 - 5.7e-15 55.5 0.0 8.8e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain Autophagy_act_C PF03987.15 EAU91905.2 - 0.049 14.2 0.3 10 6.8 0.0 3.2 3 1 0 3 3 3 0 Autophagocytosis associated protein, active-site domain HSP20 PF00011.21 EAU91906.1 - 7.1e-22 77.5 0.1 3e-21 75.5 0.0 1.8 1 1 1 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EAU91906.1 - 4.4e-11 42.2 0.0 6.9e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BBS2_Mid PF14783.6 EAU91906.1 - 0.11 12.6 0.0 2.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region FKBP26_C PF18046.1 EAU91906.1 - 0.13 12.4 0.1 12 6.1 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal Peptidase_C2 PF00648.21 EAU91907.2 - 7.7e-21 74.4 0.0 3.7e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EAU91907.2 - 1.4e-18 67.5 0.0 7.4e-08 32.7 0.0 3.8 3 1 0 3 3 3 3 Calpain large subunit, domain III MIT PF04212.18 EAU91907.2 - 5.5e-07 29.6 0.8 1.2e-06 28.4 0.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EAU91907.2 - 0.01 15.6 1.0 0.028 14.2 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat USP8_dimer PF08969.11 EAU91907.2 - 0.18 12.0 0.8 0.34 11.1 0.8 1.4 1 0 0 1 1 1 0 USP8 dimerisation domain BTB PF00651.31 EAU91908.2 - 1.3e-07 31.8 0.0 2.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TMCO5 PF14992.6 EAU91910.2 - 3.6 7.1 5.9 0.2 11.2 0.4 1.6 2 0 0 2 2 2 0 TMCO5 family F-box-like PF12937.7 EAU91911.2 - 4.6e-09 36.0 1.4 1.1e-08 34.8 1.4 1.6 1 0 0 1 1 1 1 F-box-like OPT PF03169.15 EAU91912.1 - 6e-185 616.4 40.3 7e-185 616.2 40.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BTB PF00651.31 EAU91913.2 - 0.00068 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain hDGE_amylase PF14701.6 EAU91913.2 - 0.24 10.4 7.5 0.43 9.6 7.5 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain UPF0242 PF06785.11 EAU91913.2 - 0.25 11.4 16.4 0.43 10.6 16.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Nbl1_Borealin_N PF10444.9 EAU91913.2 - 0.3 10.7 3.6 3 7.6 0.2 2.7 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal SpoIIIAH PF12685.7 EAU91913.2 - 0.95 9.3 12.7 1.4 8.7 12.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Cep57_MT_bd PF06657.13 EAU91913.2 - 8.1 7.0 15.0 0.89 10.1 6.9 2.7 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 F-box-like PF12937.7 EAU91914.1 - 4.8e-08 32.8 2.4 1.8e-07 31.0 2.4 2.0 1 0 0 1 1 1 1 F-box-like DnaJ PF00226.31 EAU91917.1 - 3.3e-11 43.1 0.0 5.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DNA_meth_N PF18284.1 EAU91920.2 - 0.29 11.1 0.9 0.6 10.1 0.9 1.5 1 0 0 1 1 1 0 DNA methylase N-terminal domain ER_lumen_recept PF00810.18 EAU91922.2 - 1.6e-56 191.2 9.7 2.4e-56 190.7 9.7 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EAU91922.2 - 0.029 14.1 5.0 0.068 12.9 0.2 3.2 3 0 0 3 3 3 0 PQ loop repeat ATPase_2 PF01637.18 EAU91924.2 - 0.00026 21.0 0.0 0.00063 19.7 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea C2 PF00168.30 EAU91924.2 - 0.001 19.3 0.1 0.001 19.3 0.1 1.7 2 0 0 2 2 2 1 C2 domain KAP_NTPase PF07693.14 EAU91924.2 - 0.0027 17.0 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain AAA PF00004.29 EAU91924.2 - 0.003 18.0 0.6 0.034 14.6 0.6 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EAU91924.2 - 0.0048 16.8 0.9 0.15 11.9 0.9 2.6 1 1 0 1 1 1 1 NACHT domain ORC3_N PF07034.11 EAU91924.2 - 0.014 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus VP4_helical PF17478.2 EAU91924.2 - 0.031 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Rotavirus VP4 helical domain AAA_16 PF13191.6 EAU91924.2 - 0.11 12.9 0.0 0.57 10.5 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EAU91924.2 - 0.11 12.9 0.0 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Lectin_leg-like PF03388.13 EAU91925.1 - 2.3e-61 207.1 0.4 3.1e-61 206.6 0.4 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 EAU91925.1 - 3.1e-05 23.6 0.0 0.0039 16.8 0.0 2.3 1 1 0 1 1 1 1 Legume lectin domain DUF3836 PF12930.7 EAU91925.1 - 0.073 12.8 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Apq12 PF12716.7 EAU91925.1 - 0.33 10.9 0.8 0.76 9.8 0.8 1.5 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis HEAT_EZ PF13513.6 EAU91926.2 - 6.8e-28 96.7 20.0 6.9e-12 45.6 0.0 11.1 11 1 1 12 12 12 4 HEAT-like repeat HEAT PF02985.22 EAU91926.2 - 1.8e-19 68.2 17.3 1.6e-05 24.7 0.0 10.1 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 EAU91926.2 - 2.1e-17 63.3 0.0 2.6e-05 24.5 0.0 7.0 5 3 3 8 8 8 4 HEAT repeats IBN_N PF03810.19 EAU91926.2 - 3.4e-07 30.1 0.0 1.7e-06 27.8 0.0 2.3 2 0 0 2 2 1 1 Importin-beta N-terminal domain Arm PF00514.23 EAU91926.2 - 1.2e-06 28.3 3.7 0.66 10.1 0.0 5.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 EAU91926.2 - 1.8e-06 28.1 0.1 0.016 15.5 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 EAU91926.2 - 2.2e-06 28.2 0.0 0.093 13.3 0.2 4.4 3 1 2 5 5 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EAU91926.2 - 3.5e-06 27.1 0.3 0.28 11.2 0.1 4.5 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EAU91926.2 - 0.00077 18.1 0.6 2 6.9 0.3 3.6 2 1 1 3 3 3 1 Adaptin N terminal region RIX1 PF08167.12 EAU91926.2 - 0.0093 15.7 0.2 18 5.0 0.0 4.6 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis Tti2 PF10521.9 EAU91926.2 - 0.012 15.2 0.1 3.2 7.2 0.1 3.5 2 2 1 3 3 3 0 Tti2 family DUF3437 PF11919.8 EAU91926.2 - 0.016 15.1 0.6 1 9.3 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 EAU91926.2 - 0.069 13.3 0.1 0.83 9.9 0.0 2.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 EAU91926.2 - 0.077 13.4 0.1 1.2 9.5 0.0 3.1 3 1 0 4 4 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FSH1 PF03959.13 EAU91927.2 - 1.2e-52 178.7 0.0 1.5e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Mito_carr PF00153.27 EAU91928.2 - 2.1e-66 219.9 3.0 3.4e-22 78.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Homeodomain PF00046.29 EAU91930.2 - 0.00035 20.4 0.1 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 Homeodomain Fic PF02661.18 EAU91937.1 - 3.4e-09 37.5 0.0 7.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Ank_2 PF12796.7 EAU91941.2 - 2.6e-53 178.6 0.0 6e-13 49.2 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EAU91941.2 - 2.7e-28 98.0 1.1 4.3e-07 30.4 0.1 7.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU91941.2 - 7.7e-27 90.4 0.0 0.00045 20.4 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 EAU91941.2 - 9.2e-27 92.3 0.4 0.0062 16.9 0.0 9.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EAU91941.2 - 1.1e-22 79.7 9.1 9.1e-07 29.0 0.2 6.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU91941.2 - 0.00014 22.1 0.0 0.00055 20.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EAU91941.2 - 0.0059 15.8 0.0 0.0099 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 EAU91941.2 - 0.033 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EAU91941.2 - 0.05 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Waikav_capsid_1 PF12264.8 EAU91941.2 - 0.18 11.3 0.2 8.6 5.8 0.0 2.3 2 0 0 2 2 2 0 Waikavirus capsid protein 1 Laminin_II PF06009.12 EAU91942.2 - 0.012 15.6 0.2 0.012 15.6 0.2 3.5 3 1 0 3 3 3 0 Laminin Domain II DivIC PF04977.15 EAU91942.2 - 0.82 9.5 8.9 7.9 6.3 0.5 3.5 3 0 0 3 3 3 0 Septum formation initiator KIP1 PF07765.12 EAU91942.2 - 0.84 9.8 0.0 0.84 9.8 0.0 3.0 4 0 0 4 4 4 0 KIP1-like protein DUF1664 PF07889.12 EAU91942.2 - 0.86 9.7 8.5 4.7 7.3 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EAU91942.2 - 1.5 8.9 4.5 1.7 8.7 0.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B562 PF07361.11 EAU91942.2 - 1.6 9.4 13.0 0.071 13.8 1.2 3.8 3 2 0 3 3 3 0 Cytochrome b562 DUF3450 PF11932.8 EAU91942.2 - 2 7.7 10.8 3.5 6.9 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) COG2 PF06148.11 EAU91942.2 - 2.4 8.2 5.7 3.1 7.9 0.0 3.4 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5082 PF16888.5 EAU91942.2 - 2.9 8.2 9.2 4.8 7.5 0.7 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) FadA PF09403.10 EAU91942.2 - 3.2 8.3 10.9 0.51 10.9 0.8 3.1 3 0 0 3 3 2 0 Adhesion protein FadA DUF4200 PF13863.6 EAU91942.2 - 7.9 6.9 15.5 0.7 10.3 0.5 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 EAU91942.2 - 8 7.0 9.5 0.42 11.1 0.6 3.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 EAU91942.2 - 9.7 5.8 11.7 0.65 9.6 0.2 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Lebercilin PF15619.6 EAU91943.1 - 0.18 11.5 3.6 6.3 6.4 0.1 3.1 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF5082 PF16888.5 EAU91943.1 - 0.69 10.2 6.2 1.1 9.6 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) FlxA PF14282.6 EAU91943.1 - 1.7 8.7 5.4 56 3.8 5.4 2.6 1 1 0 1 1 1 0 FlxA-like protein Tropomyosin_1 PF12718.7 EAU91943.1 - 4.8 7.3 8.4 2.9 8.0 1.4 2.9 3 0 0 3 3 3 0 Tropomyosin like Synaptobrevin PF00957.21 EAU91943.1 - 5 7.0 6.4 1.1 9.1 0.1 2.7 3 0 0 3 3 3 0 Synaptobrevin ARD PF03079.14 EAU91946.1 - 9.5e-46 155.8 0.0 1.1e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EAU91946.1 - 9.1e-10 38.1 0.0 1.6e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EAU91946.1 - 3.7e-06 26.9 0.0 5.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EAU91946.1 - 0.00031 20.4 0.0 0.0005 19.7 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 EAU91946.1 - 0.088 12.5 0.0 0.16 11.6 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.12 EAU91946.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.14 EAU91947.1 - 2.4e-37 128.5 0.4 3e-37 128.2 0.4 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EAU91947.1 - 8.4e-08 31.8 0.1 1.5e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EAU91947.1 - 7.4e-07 29.1 0.1 1.2e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Ribosomal_L33 PF00471.20 EAU91948.1 - 5.8e-08 33.1 0.0 7.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.8 EAU91948.1 - 0.071 12.7 0.0 0.095 12.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Mito_carr PF00153.27 EAU91957.2 - 4.4e-46 154.8 1.4 3.3e-20 71.8 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein RNase_T PF00929.24 EAU91958.1 - 2.7e-10 41.0 0.0 4.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EAU91958.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease Alpha_kinase PF02816.18 EAU91960.2 - 1.4e-21 77.5 0.0 2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Spc7 PF08317.11 EAU91963.2 - 0.22 10.3 14.8 0.43 9.4 14.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 EAU91964.1 - 6.7 7.2 8.1 17 5.9 1.1 4.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper APH PF01636.23 EAU91966.1 - 7.9e-13 48.9 0.9 1.3e-12 48.2 0.9 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAU91966.1 - 1.9e-05 24.4 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EAU91966.1 - 0.0029 17.2 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Cpn60_TCP1 PF00118.24 EAU91967.2 - 1.2e-138 462.8 0.0 1.5e-138 462.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1996 PF09362.10 EAU91972.2 - 2.5e-44 152.0 0.0 3.5e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU91972.2 - 4e-12 45.9 15.3 1.3e-11 44.3 15.3 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1996 PF09362.10 EAU91973.2 - 3.4e-66 223.6 0.0 4.4e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU91973.2 - 1.9e-11 43.7 15.1 1.9e-11 43.7 15.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF1996 PF09362.10 EAU91974.2 - 4.2e-66 223.3 0.1 5.5e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU91974.2 - 1.9e-11 43.7 15.1 1.9e-11 43.7 15.1 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain FAD_binding_3 PF01494.19 EAU91975.1 - 3.4e-14 52.9 4.1 2.4e-07 30.3 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 EAU91975.1 - 0.0072 15.4 0.0 0.017 14.2 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 EAU91975.1 - 0.029 14.6 0.1 0.062 13.5 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EAU91975.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding PMEI PF04043.15 EAU91975.1 - 0.088 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DAO PF01266.24 EAU91975.1 - 0.4 10.2 2.4 1.5 8.3 0.4 2.2 2 1 1 3 3 3 0 FAD dependent oxidoreductase DnaJ PF00226.31 EAU91976.2 - 6.2e-23 80.7 2.9 7.5e-23 80.4 1.4 1.9 2 0 0 2 2 2 1 DnaJ domain DUF4491 PF14898.6 EAU91976.2 - 0.11 13.0 1.3 0.23 12.0 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) FxsA PF04186.13 EAU91977.1 - 0.01 15.9 3.9 0.018 15.2 3.9 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein DUF2207 PF09972.9 EAU91977.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Tmemb_9 PF05434.11 EAU91977.1 - 0.28 11.1 0.8 0.61 10.0 0.1 1.9 2 0 0 2 2 2 0 TMEM9 DUF4191 PF13829.6 EAU91977.1 - 0.35 10.2 3.2 0.55 9.5 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Orf78 PF06024.12 EAU91977.1 - 0.62 10.4 3.9 0.51 10.7 0.1 2.5 3 0 0 3 3 3 0 Orf78 (ac78) UL45 PF05473.12 EAU91977.1 - 0.67 9.6 3.2 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Ctr PF04145.15 EAU91977.1 - 1 10.0 4.6 12 6.5 4.6 2.2 1 1 0 1 1 1 0 Ctr copper transporter family MAP65_ASE1 PF03999.12 EAU91977.1 - 1.7 7.3 13.8 2.6 6.7 13.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TMEM154 PF15102.6 EAU91977.1 - 7.8 6.4 9.3 0.63 9.9 0.4 2.4 2 0 0 2 2 2 0 TMEM154 protein family Shisa PF13908.6 EAU91977.1 - 8.3 6.6 7.0 4.9 7.4 0.1 2.6 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Cu-oxidase PF00394.22 EAU91978.1 - 2.1e-44 151.4 0.1 7.7e-42 143.1 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU91978.1 - 7e-39 132.5 0.2 3.5e-38 130.3 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU91978.1 - 2.1e-34 118.2 3.0 2.5e-32 111.5 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase CFEM PF05730.11 EAU91979.1 - 1e-10 41.5 14.1 1.6e-10 40.9 14.1 1.3 1 0 0 1 1 1 1 CFEM domain MSA-2c PF12238.8 EAU91979.1 - 0.98 9.4 6.1 1.2 9.1 6.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c CHAT PF12770.7 EAU91980.2 - 5.1e-31 108.1 0.0 1.5e-30 106.6 0.0 1.8 1 0 0 1 1 1 1 CHAT domain TPR_14 PF13428.6 EAU91980.2 - 0.00046 20.8 13.9 2.6 9.1 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 EAU91980.2 - 0.00074 19.5 4.3 43 4.7 0.0 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EAU91980.2 - 0.0053 16.6 14.9 15 5.6 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat Peptidase_S46 PF10459.9 EAU91980.2 - 0.036 12.7 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 Laminin_II PF06009.12 EAU91980.2 - 0.13 12.3 0.6 0.66 10.0 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Peptidase_C25 PF01364.18 EAU91980.2 - 0.22 10.6 0.3 1 8.5 0.1 1.9 2 0 0 2 2 2 0 Peptidase family C25 CRISPR_Cse2 PF09485.10 EAU91980.2 - 2.6 8.6 8.2 7.6 7.1 0.1 4.9 4 2 0 4 4 4 0 CRISPR-associated protein Cse2 (CRISPR_cse2) INO80_Ies4 PF08193.11 EAU91981.2 - 1 9.3 13.6 1.7 8.6 13.5 1.4 1 1 0 1 1 1 0 INO80 complex subunit Ies4 DUF3592 PF12158.8 EAU91982.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) DUF3984 PF13136.6 EAU91982.1 - 0.45 9.9 9.3 0.6 9.5 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RhoGAP PF00620.27 EAU91983.1 - 4.6e-11 42.8 0.0 2.3e-10 40.5 0.0 2.2 1 1 0 1 1 1 1 RhoGAP domain FAM176 PF14851.6 EAU91983.1 - 0.12 12.0 1.6 0.28 10.9 1.6 1.5 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 EAU91983.1 - 2.4 8.0 6.1 5.3 6.9 2.7 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region YfhO PF09586.10 EAU91984.2 - 0.08 11.2 1.2 0.095 10.9 1.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Cu-oxidase PF00394.22 EAU91985.2 - 6.4e-44 149.9 0.0 1.4e-41 142.3 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU91985.2 - 2e-37 127.8 0.5 1.8e-35 121.6 0.2 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU91985.2 - 1.4e-36 125.2 1.5 2.4e-34 118.0 0.0 2.8 2 1 0 2 2 2 2 Multicopper oxidase Peptidase_M22 PF00814.25 EAU91987.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family Hydrolase_4 PF12146.8 EAU91987.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GMC_oxred_C PF05199.13 EAU91988.2 - 3.8e-26 92.3 1.0 7.8e-26 91.3 1.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase RNase_PH PF01138.21 EAU91989.2 - 5.4e-18 65.8 0.4 1.7e-17 64.2 0.2 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EAU91989.2 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 F-box-like PF12937.7 EAU91990.1 - 3.5e-08 33.2 5.6 6e-08 32.5 2.5 2.8 3 0 0 3 3 3 1 F-box-like Lzipper-MIP1 PF14389.6 EAU91990.1 - 0.17 12.2 1.6 0.98 9.8 0.1 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 EPL1 PF10513.9 EAU91991.2 - 1.7 9.0 5.5 2.2 8.7 0.1 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like zf-MYND PF01753.18 EAU91994.1 - 4.1e-11 42.8 12.3 6.1e-11 42.2 12.3 1.3 1 0 0 1 1 1 1 MYND finger TPR_10 PF13374.6 EAU91994.1 - 0.00073 19.3 0.3 0.64 10.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU91994.1 - 0.0025 18.1 0.3 0.92 9.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EAU91994.1 - 0.0046 17.0 0.4 3.4 8.0 0.7 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-C6H2 PF15801.5 EAU91994.1 - 0.012 15.9 10.3 0.019 15.3 10.3 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MIT PF04212.18 EAU91994.1 - 0.012 15.6 0.1 2.6 8.2 0.2 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EAU91994.1 - 0.026 14.3 0.4 1.1 9.2 1.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU91994.1 - 0.032 15.0 0.3 16 6.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EAU91994.1 - 0.034 13.5 0.2 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 MalT-like TPR region TPR_11 PF13414.6 EAU91994.1 - 0.072 12.8 4.6 0.65 9.7 0.0 2.7 3 0 0 3 3 3 0 TPR repeat PolC_DP2 PF03833.13 EAU91994.1 - 0.11 10.3 2.0 0.14 10.0 2.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 V-ATPase_G PF03179.15 EAU91994.1 - 0.14 12.7 0.4 3.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Herpes_gE PF02480.16 EAU91996.2 - 0.0026 16.6 0.0 0.0045 15.8 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 EAU91996.2 - 0.0075 17.1 0.0 0.018 15.9 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EAU91996.2 - 0.03 14.2 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family Syndecan PF01034.20 EAU91996.2 - 0.17 11.9 0.1 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Syndecan domain CcmD PF04995.14 EAU91996.2 - 0.33 11.1 2.3 0.72 10.0 2.3 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) zf-MYND PF01753.18 EAU91997.1 - 4e-10 39.6 16.4 6.6e-10 38.9 16.4 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EAU91997.1 - 0.0034 17.6 11.1 0.0059 16.9 11.1 1.3 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 EAU91997.1 - 0.016 13.1 3.4 0.019 12.9 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TPR_21 PF09976.9 EAU91997.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain zf-HIT PF04438.16 EAU91997.1 - 0.26 11.2 9.2 0.47 10.4 9.2 1.4 1 0 0 1 1 1 0 HIT zinc finger Rhodanese_C PF12368.8 EAU91997.1 - 0.88 10.0 9.0 1.7 9.1 9.0 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal zf-Mss51 PF13824.6 EAU91997.1 - 6.2 7.0 8.1 16 5.7 8.1 1.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 p450 PF00067.22 EAU91998.2 - 8.7e-54 183.0 0.0 1.4e-53 182.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 EAU92000.2 - 5e-89 298.9 0.7 1.2e-67 228.5 0.1 2.8 2 1 0 2 2 2 2 Aldehyde dehydrogenase family F-box PF00646.33 EAU92001.2 - 0.00019 21.2 0.1 0.00044 20.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92001.2 - 0.017 15.0 1.5 0.027 14.3 0.2 2.0 2 0 0 2 2 2 0 F-box-like RGI_lyase PF18370.1 EAU92001.2 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Rhamnogalacturonan I lyases beta-sheet domain EF-hand_1 PF00036.32 EAU92003.1 - 2.3e-18 64.3 0.7 3.2e-06 26.3 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EAU92003.1 - 1.9e-16 58.5 1.7 7.7e-07 28.6 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EAU92003.1 - 1.1e-15 57.8 0.4 2e-07 31.4 0.5 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EAU92003.1 - 2.2e-12 45.9 1.1 0.009 15.5 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EAU92003.1 - 5.7e-11 42.1 1.6 4.8e-05 23.1 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain pair F-box-like PF12937.7 EAU92004.2 - 1.5e-12 47.2 0.0 5e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92004.2 - 0.0062 16.4 0.1 0.033 14.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain MMR_HSR1 PF01926.23 EAU92006.2 - 1.1e-11 44.7 0.1 2e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU92006.2 - 3.8e-07 29.6 0.1 3.8e-07 29.6 0.1 1.7 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EAU92006.2 - 4.7e-07 30.0 0.3 1.3e-06 28.6 0.3 1.7 1 1 0 1 1 1 1 Dynamin family Roc PF08477.13 EAU92006.2 - 5.3e-07 29.9 0.1 1.3e-06 28.6 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EAU92006.2 - 9.4e-06 25.3 0.1 3.6e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EAU92006.2 - 1.5e-05 24.9 0.0 0.00072 19.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EAU92006.2 - 0.00019 20.9 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family IIGP PF05049.13 EAU92006.2 - 0.00081 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EAU92006.2 - 0.0039 17.7 0.1 0.0089 16.5 0.2 1.5 1 1 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 EAU92006.2 - 0.0041 16.7 0.1 0.0064 16.0 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 EAU92006.2 - 0.0084 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EAU92006.2 - 0.018 15.3 0.1 0.054 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU92006.2 - 0.019 15.4 0.0 0.075 13.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 EAU92006.2 - 0.093 13.1 0.1 0.23 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain COesterase PF00135.28 EAU92008.2 - 2.2e-74 251.2 0.0 2.8e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU92008.2 - 1.5e-06 28.2 0.1 1.9e-05 24.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU92008.2 - 0.025 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box PF00646.33 EAU92009.2 - 7.4e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92009.2 - 2.2e-05 24.3 0.0 5.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like Cu-oxidase PF00394.22 EAU92011.2 - 2.3e-41 141.6 0.0 9.1e-38 129.9 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU92011.2 - 2.9e-34 117.6 1.5 3.5e-33 114.1 0.7 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU92011.2 - 4.1e-33 114.0 6.3 3.7e-31 107.7 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase F-box-like PF12937.7 EAU92013.2 - 1.3e-05 25.0 0.1 3.5e-05 23.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92013.2 - 2.2e-05 24.2 0.0 5.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain TPM_phosphatase PF04536.14 EAU92013.2 - 0.16 12.2 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 TPM domain NAD_binding_5 PF07994.12 EAU92014.1 - 6.5e-143 475.9 0.0 7.8e-143 475.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EAU92014.1 - 2.2e-43 147.0 0.2 5e-43 145.8 0.0 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Prot_ATP_ID_OB PF16450.5 EAU92014.1 - 0.013 15.4 0.6 0.36 10.8 0.1 2.7 2 0 0 2 2 2 0 Proteasomal ATPase OB C-terminal domain Bromodomain PF00439.25 EAU92016.1 - 5.6e-23 80.8 0.9 1.7e-22 79.3 0.5 1.9 1 1 1 2 2 2 1 Bromodomain Bromo_TP PF07524.13 EAU92016.1 - 1.1e-06 28.5 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NIF PF03031.18 EAU92017.1 - 3.5e-39 134.1 0.0 5.1e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Foie-gras_1 PF11817.8 EAU92017.1 - 0.0018 17.9 0.4 0.0034 17.0 0.4 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 DUF1206 PF06724.11 EAU92017.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) KIAA1430 PF13879.6 EAU92017.1 - 0.026 15.3 0.4 0.07 13.9 0.4 1.7 1 0 0 1 1 1 0 KIAA1430 homologue DUF737 PF05300.11 EAU92017.1 - 0.058 13.8 2.6 0.29 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Lipase_GDSL_2 PF13472.6 EAU92018.1 - 4.8e-07 30.4 1.3 7.7e-07 29.7 1.3 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU92018.1 - 4.8e-06 26.7 0.0 7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.18 EAU92019.1 - 2.1e-09 37.1 1.3 3.8e-09 36.3 1.3 1.4 1 0 0 1 1 1 1 Fungal cellulose binding domain RibD_C PF01872.17 EAU92019.1 - 0.0075 16.1 0.9 1.7 8.4 0.0 2.9 1 1 1 2 2 2 2 RibD C-terminal domain CBM_1 PF00734.18 EAU92020.1 - 3.2e-08 33.4 5.2 4.5e-08 32.9 5.2 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.18 EAU92021.1 - 7e-10 38.7 1.3 1.2e-09 37.9 1.3 1.4 1 0 0 1 1 1 1 Fungal cellulose binding domain Collagen PF01391.18 EAU92021.1 - 0.36 10.6 6.4 0.054 13.3 2.5 1.7 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) CBM_1 PF00734.18 EAU92022.1 - 1.4e-10 40.9 1.5 2.4e-10 40.2 1.5 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.18 EAU92023.2 - 3.2e-08 33.4 6.5 6.1e-08 32.5 6.5 1.4 1 0 0 1 1 1 1 Fungal cellulose binding domain DDE_3 PF13358.6 EAU92024.2 - 6.3e-07 29.3 0.0 0.032 14.0 0.0 2.8 2 0 0 2 2 2 2 DDE superfamily endonuclease CBM_1 PF00734.18 EAU92025.1 - 6.2e-06 26.1 0.5 1e-05 25.4 0.5 1.2 1 0 0 1 1 1 1 Fungal cellulose binding domain F-box PF00646.33 EAU92026.1 - 0.0026 17.6 0.6 0.015 15.1 0.1 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EAU92026.1 - 0.0031 17.4 0.0 0.027 14.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like RET_CLD1 PF17756.1 EAU92026.1 - 0.16 12.3 0.1 0.53 10.6 0.0 1.8 2 0 0 2 2 2 0 RET Cadherin like domain 1 CENP-B_dimeris PF09026.10 EAU92026.1 - 0.55 10.6 6.9 15 6.0 4.9 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SR-25 PF10500.9 EAU92026.1 - 1.2 8.7 4.0 2 7.9 4.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RhoGAP PF00620.27 EAU92027.2 - 1.2e-41 142.1 0.0 3.1e-41 140.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 EAU92027.2 - 1.5e-10 41.6 0.0 3.4e-08 33.9 0.0 3.0 2 1 0 2 2 2 1 RasGEF domain PH_9 PF15410.6 EAU92027.2 - 4.5e-06 27.0 0.0 1.9e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EAU92027.2 - 6.6e-06 26.6 0.0 0.022 15.3 0.0 2.5 2 0 0 2 2 2 2 PH domain RasGEF_N PF00618.20 EAU92027.2 - 0.0043 17.3 0.0 0.047 13.9 0.0 2.9 2 1 0 2 2 2 1 RasGEF N-terminal motif Ribosomal_L37 PF08561.10 EAU92028.1 - 1e-16 61.6 6.5 2.4e-15 57.1 0.5 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Tyrosinase PF00264.20 EAU92029.1 - 8.9e-36 124.2 0.0 1.3e-35 123.7 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.20 EAU92030.2 - 2e-29 103.5 0.0 2.9e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.19 EAU92031.2 - 1.9e-13 50.4 0.3 8.9e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EAU92031.2 - 1.1e-07 32.0 1.2 2.9e-07 30.6 1.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EAU92031.2 - 4.1e-07 29.9 7.7 0.00022 20.9 5.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU92031.2 - 8.3e-07 28.5 2.3 0.0002 20.7 2.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EAU92031.2 - 1.7e-06 27.0 0.3 4.9e-06 25.5 0.3 1.7 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EAU92031.2 - 4.5e-06 26.2 0.4 0.078 12.2 0.4 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EAU92031.2 - 5e-06 25.8 0.9 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 EAU92031.2 - 2.7e-05 23.2 1.7 0.037 12.9 2.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 EAU92031.2 - 0.0015 17.7 2.6 0.0038 16.4 2.6 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EAU92031.2 - 0.0016 19.0 2.0 0.0027 18.2 0.6 2.2 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EAU92031.2 - 0.0028 16.8 5.1 0.0052 15.9 5.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EAU92031.2 - 0.0042 16.3 0.9 0.0075 15.5 0.9 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EAU92031.2 - 0.0044 16.4 0.5 0.0078 15.6 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EAU92031.2 - 0.0076 15.5 3.2 0.92 8.7 2.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 EAU92031.2 - 0.022 14.6 0.7 0.078 12.8 0.1 2.2 2 0 0 2 2 2 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EAU92031.2 - 0.13 11.9 0.5 0.23 11.0 0.5 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EAU92031.2 - 0.22 11.5 1.9 2.8 7.9 1.0 2.8 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Cadherin_4 PF17803.1 EAU92031.2 - 1.8 9.2 7.8 0.94 10.1 2.6 2.4 2 0 0 2 2 2 0 Bacterial cadherin-like domain Cu-oxidase PF00394.22 EAU92032.2 - 2.7e-45 154.3 0.0 6.2e-41 140.2 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU92032.2 - 1.1e-39 135.1 1.7 3.9e-37 126.9 0.2 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU92032.2 - 1.7e-35 121.7 6.4 6e-34 116.7 0.2 3.2 3 1 0 3 3 3 2 Multicopper oxidase DUF4054 PF13262.6 EAU92032.2 - 0.26 11.3 0.1 0.66 10.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Cyclin_N PF00134.23 EAU92037.2 - 4.7e-11 42.5 0.0 1e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain F-box PF00646.33 EAU92038.2 - 7.1e-05 22.6 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92038.2 - 0.0075 16.1 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF4568 PF15132.6 EAU92038.2 - 0.016 14.6 0.1 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4568) Antimicrobial10 PF08105.11 EAU92040.2 - 0.11 12.5 0.9 0.27 11.4 0.9 1.6 1 0 0 1 1 1 0 Metchnikowin family aGPT-Pplase1 PF18723.1 EAU92041.2 - 0.009 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 KR PF08659.10 EAU92048.1 - 1.9e-06 27.9 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EAU92048.1 - 0.00085 18.8 0.0 0.0028 17.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Asp-B-Hydro_N PF05279.11 EAU92048.1 - 0.33 11.0 7.1 0.49 10.4 7.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Rtf2 PF04641.12 EAU92048.1 - 0.67 9.3 8.5 1.4 8.3 8.5 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger CEP63 PF17045.5 EAU92050.1 - 8.3e-05 22.6 5.4 0.00017 21.6 5.4 1.5 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Myosin_tail_1 PF01576.19 EAU92050.1 - 0.00021 19.3 6.2 0.00031 18.7 6.2 1.2 1 0 0 1 1 1 1 Myosin tail HIP1_clath_bdg PF16515.5 EAU92050.1 - 0.00034 21.2 7.4 0.00034 21.2 7.4 2.3 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 EAU92050.1 - 0.0008 19.4 6.2 0.35 11.0 0.1 2.5 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 EAU92050.1 - 0.0012 17.8 5.9 0.0022 16.9 5.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein BST2 PF16716.5 EAU92050.1 - 0.0021 18.6 9.8 0.0083 16.7 8.0 2.6 2 1 0 2 2 1 1 Bone marrow stromal antigen 2 FPP PF05911.11 EAU92050.1 - 0.0027 16.0 6.8 0.0028 15.9 5.9 1.4 2 0 0 2 2 1 1 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 EAU92050.1 - 0.0027 18.2 5.6 0.0045 17.5 5.6 1.3 1 0 0 1 1 1 1 Fez1 HMMR_N PF15905.5 EAU92050.1 - 0.0056 16.2 5.3 0.0089 15.5 5.3 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 EAU92050.1 - 0.0057 16.8 2.4 0.0096 16.1 2.4 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 EAU92050.1 - 0.0086 16.0 4.9 0.017 15.1 3.2 2.2 1 1 1 2 2 2 1 FlxA-like protein DUF1192 PF06698.11 EAU92050.1 - 0.012 15.7 3.6 3.2 7.9 0.9 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF1192) Yuri_gagarin PF15934.5 EAU92050.1 - 0.021 14.7 0.8 0.034 14.0 0.8 1.3 1 0 0 1 1 1 0 Yuri gagarin Spc29 PF17082.5 EAU92050.1 - 0.023 14.6 2.4 0.044 13.6 2.4 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Exonuc_VII_L PF02601.15 EAU92050.1 - 0.024 14.2 2.5 0.05 13.2 2.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATG16 PF08614.11 EAU92050.1 - 0.027 14.7 15.0 0.13 12.5 8.5 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1043 PF06295.12 EAU92050.1 - 0.03 14.3 1.7 2.3 8.2 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ERM PF00769.19 EAU92050.1 - 0.034 14.0 10.3 0.067 13.0 10.3 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HemX PF04375.14 EAU92050.1 - 0.037 13.3 4.1 0.061 12.6 4.1 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase APG6_N PF17675.1 EAU92050.1 - 0.042 14.4 11.6 0.12 12.9 11.6 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region HAP1_N PF04849.13 EAU92050.1 - 0.049 12.8 7.9 0.084 12.1 7.9 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Lebercilin PF15619.6 EAU92050.1 - 0.057 13.1 11.5 0.072 12.7 1.4 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 EAU92050.1 - 0.1 11.7 7.9 0.96 8.5 7.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 EAU92050.1 - 0.1 12.3 4.0 0.23 11.2 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) THOC7 PF05615.13 EAU92050.1 - 0.12 12.7 10.1 1.4 9.2 9.9 2.3 1 1 0 1 1 1 0 Tho complex subunit 7 DUF641 PF04859.12 EAU92050.1 - 0.13 12.6 5.4 0.091 13.1 2.7 2.2 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) KASH_CCD PF14662.6 EAU92050.1 - 0.14 12.0 10.4 0.4 10.5 10.4 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF3552 PF12072.8 EAU92050.1 - 0.16 11.3 10.3 0.33 10.4 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TMF_DNA_bd PF12329.8 EAU92050.1 - 0.18 11.8 10.9 0.038 14.0 6.2 2.4 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding SH3BP5 PF05276.14 EAU92050.1 - 0.18 11.6 4.9 0.065 13.0 2.0 1.8 2 0 0 2 2 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF5082 PF16888.5 EAU92050.1 - 0.19 12.0 4.0 0.54 10.6 4.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Macoilin PF09726.9 EAU92050.1 - 0.22 10.0 2.7 0.32 9.5 2.7 1.3 1 0 0 1 1 1 0 Macoilin family GAS PF13851.6 EAU92050.1 - 0.23 10.8 7.4 1.4 8.2 8.1 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 EAU92050.1 - 0.24 9.5 4.3 0.45 8.6 4.3 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FAM76 PF16046.5 EAU92050.1 - 0.25 10.7 6.1 0.38 10.0 5.6 1.5 1 1 0 1 1 1 0 FAM76 protein CLZ PF16526.5 EAU92050.1 - 0.25 11.7 8.6 0.13 12.6 2.8 2.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 EAU92050.1 - 0.26 11.4 9.3 0.67 10.0 9.3 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 EAU92050.1 - 0.28 10.5 5.2 0.48 9.7 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EAU92050.1 - 0.34 11.3 4.7 8.4 6.9 0.0 3.6 2 1 2 4 4 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 EAU92050.1 - 0.34 9.5 1.4 0.57 8.7 1.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 EAU92050.1 - 0.41 11.0 7.5 5.1 7.5 7.5 2.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nsp1_C PF05064.13 EAU92050.1 - 0.56 10.0 3.9 0.31 10.8 1.6 1.8 2 0 0 2 2 1 0 Nsp1-like C-terminal region bZIP_2 PF07716.15 EAU92050.1 - 0.66 10.1 8.1 1.9 8.6 2.0 2.8 2 0 0 2 2 2 0 Basic region leucine zipper CENP-F_leu_zip PF10473.9 EAU92050.1 - 0.77 9.8 11.0 0.46 10.5 7.2 2.4 3 0 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EAU92050.1 - 0.88 9.6 4.1 0.64 10.1 1.4 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) OmpH PF03938.14 EAU92050.1 - 0.89 9.9 8.5 0.53 10.6 6.2 1.8 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) DUF4200 PF13863.6 EAU92050.1 - 0.92 9.9 11.1 0.55 10.6 8.4 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Spc24 PF08286.11 EAU92050.1 - 1.3 9.3 7.4 0.79 10.0 0.5 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Seryl_tRNA_N PF02403.22 EAU92050.1 - 1.7 8.9 5.9 4.6 7.5 1.2 2.6 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 EAU92050.1 - 1.8 8.9 5.9 3.7 7.9 0.2 3.1 3 1 1 4 4 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DMPK_coil PF08826.10 EAU92050.1 - 1.9 8.7 13.6 0.095 12.8 2.5 3.7 3 1 1 4 4 3 0 DMPK coiled coil domain like SOGA PF11365.8 EAU92050.1 - 2.1 9.5 6.8 21 6.3 0.7 2.5 1 1 1 2 2 2 0 Protein SOGA Prefoldin PF02996.17 EAU92050.1 - 4.7 7.2 6.4 5.7 6.9 0.5 3.0 2 1 1 3 3 3 0 Prefoldin subunit DivIC PF04977.15 EAU92050.1 - 5.5 6.8 7.5 4.5 7.1 1.5 3.0 2 1 2 4 4 4 0 Septum formation initiator CCDC-167 PF15188.6 EAU92050.1 - 5.5 7.4 8.0 2 8.8 4.6 2.0 2 1 1 3 3 1 0 Coiled-coil domain-containing protein 167 ZapB PF06005.12 EAU92050.1 - 7.4 7.1 11.2 7 7.2 2.8 3.2 2 1 1 3 3 3 0 Cell division protein ZapB CysG_dimeriser PF10414.9 EAU92052.2 - 1.2e-06 28.1 0.0 4.4 7.1 0.0 5.2 5 0 0 5 5 5 3 Sirohaem synthase dimerisation region DUF1323 PF07037.11 EAU92052.2 - 0.0009 19.6 0.2 31 5.0 0.0 4.2 2 2 3 5 5 5 2 Putative transcription regulator (DUF1323) ATXN-1_C PF12547.8 EAU92052.2 - 0.013 15.8 0.1 1.7e+02 2.7 0.0 4.4 5 0 0 5 5 5 0 Capicua transcriptional repressor modulator Haemadin PF09065.10 EAU92055.1 - 2.4 8.1 5.3 1 9.2 1.6 2.3 2 0 0 2 2 2 0 Haemadin Ank_2 PF12796.7 EAU92058.2 - 8.7e-35 119.2 0.0 3.3e-10 40.4 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU92058.2 - 4e-31 103.6 0.0 0.00062 20.0 0.0 8.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EAU92058.2 - 3.5e-28 97.3 3.0 4.7e-08 33.2 0.1 6.6 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU92058.2 - 5e-25 87.6 0.1 1.2e-05 25.8 0.0 7.0 4 3 4 8 8 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU92058.2 - 1.1e-23 82.5 0.0 0.013 15.9 0.0 8.1 7 0 0 7 7 7 5 Ankyrin repeat NACHT PF05729.12 EAU92058.2 - 3.6e-05 23.7 0.4 7.6e-05 22.7 0.1 1.7 2 0 0 2 2 1 1 NACHT domain AAA_22 PF13401.6 EAU92058.2 - 0.00045 20.5 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU92058.2 - 0.0041 17.5 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EAU92058.2 - 0.0053 16.5 0.1 0.018 14.8 0.0 2.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EAU92058.2 - 0.0084 16.5 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Se-cys_synth_N PF12390.8 EAU92058.2 - 0.023 14.9 6.1 1.4 9.2 0.3 5.1 4 2 0 4 4 4 0 Selenocysteine synthase N terminal AAA_14 PF13173.6 EAU92058.2 - 0.066 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 EAU92058.2 - 0.07 12.1 0.0 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 cobW PF02492.19 EAU92058.2 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ank_2 PF12796.7 EAU92059.2 - 4.9e-73 241.7 0.0 9.7e-14 51.7 0.0 7.7 4 3 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU92059.2 - 3.4e-69 220.5 9.8 0.0027 18.0 0.0 16.2 16 0 0 16 16 15 14 Ankyrin repeat Ank_5 PF13857.6 EAU92059.2 - 9.9e-55 181.9 17.3 3.4e-05 24.0 0.0 15.1 2 1 13 15 15 15 13 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU92059.2 - 1.3e-38 130.8 1.1 1.4e-06 28.7 0.0 10.4 7 1 3 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 EAU92059.2 - 2.3e-24 84.7 21.1 0.7 10.4 0.0 16.6 14 3 3 17 17 17 4 Ankyrin repeat VWA_3_C PF18571.1 EAU92059.2 - 1.3e-14 53.8 27.1 0.46 10.4 0.1 12.8 10 3 3 13 13 13 4 von Willebrand factor type A C-terminal domain HHH_5 PF14520.6 EAU92059.2 - 3.9e-06 27.4 18.0 21 5.8 0.1 11.7 3 2 8 11 11 11 0 Helix-hairpin-helix domain E1_dh PF00676.20 EAU92059.2 - 0.021 13.8 8.4 7.4 5.4 0.0 5.0 3 1 3 6 6 6 0 Dehydrogenase E1 component NACHT PF05729.12 EAU92059.2 - 0.11 12.4 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Phage_TAC_10 PF10963.8 EAU92059.2 - 0.18 12.0 0.1 7.4 6.8 0.0 4.0 3 1 0 3 3 3 0 Phage tail assembly chaperone PKS_DE PF18369.1 EAU92059.2 - 0.45 11.1 9.5 58 4.4 0.1 5.0 4 0 0 4 4 4 0 Polyketide synthase dimerisation element domain Ank_2 PF12796.7 EAU92062.2 - 6e-95 312.0 0.0 5.6e-18 65.3 0.0 7.0 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU92062.2 - 2.2e-69 221.1 1.4 9.4e-06 25.6 0.0 13.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 EAU92062.2 - 6.9e-66 217.8 0.1 1.4e-10 41.5 0.0 11.2 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU92062.2 - 2e-63 209.6 11.7 1.8e-09 37.7 0.0 11.6 2 1 10 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 EAU92062.2 - 1.3e-61 202.5 0.5 0.00012 22.3 0.0 13.6 14 0 0 14 14 13 11 Ankyrin repeat NapD PF03927.13 EAU92062.2 - 4.7e-08 33.0 7.8 7.4 6.7 0.0 9.5 3 2 7 10 10 10 1 NapD protein NACHT PF05729.12 EAU92062.2 - 1.3e-05 25.2 0.2 5.1e-05 23.3 0.2 2.1 1 0 0 1 1 1 1 NACHT domain HHH_5 PF14520.6 EAU92062.2 - 0.00044 20.8 0.1 33 5.2 0.0 5.8 5 0 0 5 5 5 0 Helix-hairpin-helix domain AAA_16 PF13191.6 EAU92062.2 - 0.00045 20.7 0.1 0.0013 19.2 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU92062.2 - 0.00075 19.8 0.1 0.0025 18.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EAU92062.2 - 0.0043 16.1 0.1 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EAU92062.2 - 0.032 14.3 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF503 PF04456.12 EAU92062.2 - 0.032 14.1 0.1 2.1 8.3 0.0 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF503) AAA_30 PF13604.6 EAU92062.2 - 0.049 13.3 0.0 0.18 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EAU92062.2 - 0.054 13.4 0.1 0.44 10.4 0.0 2.6 2 1 0 3 3 3 0 NTPase cobW PF02492.19 EAU92062.2 - 0.06 12.9 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EAU92062.2 - 0.085 12.8 0.1 2.8 7.9 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 EAU92062.2 - 0.1 11.8 0.0 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF4951 PF16309.5 EAU92062.2 - 2.3 8.3 4.5 13 5.9 0.2 3.8 3 1 2 5 5 5 0 Domian of unknown function (DUF4951) E3_binding PF02817.17 EAU92062.2 - 6.2 7.3 9.9 63 4.0 0.0 5.5 7 0 0 7 7 5 0 e3 binding domain Radial_spoke PF04712.12 EAU92065.1 - 0.33 9.8 2.5 0.61 9.0 2.5 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 EAU92065.1 - 0.62 8.1 4.9 0.91 7.5 4.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 EAU92065.1 - 0.96 9.1 5.9 2.4 7.8 5.6 1.8 1 1 0 1 1 1 0 FAM176 family NOA36 PF06524.12 EAU92065.1 - 9 5.5 7.7 17 4.6 7.7 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3813 PF12758.7 EAU92066.2 - 0.0014 18.9 3.2 0.39 11.1 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3813) Fzo_mitofusin PF04799.13 EAU92067.2 - 0.03 13.9 0.6 0.045 13.3 0.6 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF5394 PF17372.2 EAU92067.2 - 0.12 11.9 1.1 0.17 11.4 1.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5394) CxC4 PF18717.1 EAU92068.2 - 6.4e-46 155.4 0.0 1.2e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases DUF240 PF03086.14 EAU92068.2 - 0.0097 15.8 0.0 3.9 7.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF240) HEAT_EZ PF13513.6 EAU92069.1 - 2.8e-05 24.5 0.6 0.032 14.7 0.0 4.3 3 1 1 4 4 4 2 HEAT-like repeat DUF3385 PF11865.8 EAU92069.1 - 0.00092 19.2 0.0 0.64 9.9 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) HEAT PF02985.22 EAU92069.1 - 0.0011 19.0 0.1 0.0071 16.5 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.6 EAU92069.1 - 0.0048 17.3 0.1 0.031 14.7 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EAU92069.1 - 0.11 13.1 0.0 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 EAU92069.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Importin_rep_4 PF18808.1 EAU92070.1 - 1.9e-18 66.5 0.1 3.8e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Importin repeat HEAT PF02985.22 EAU92070.1 - 0.037 14.3 0.1 36 5.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 EAU92070.1 - 0.087 13.4 0.1 0.61 10.7 0.1 2.6 2 0 0 2 2 2 0 HEAT-like repeat Peptidase_M43 PF05572.13 EAU92072.2 - 1.8e-15 57.2 0.0 2.9e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU92072.2 - 1e-08 35.6 1.5 2e-08 34.7 1.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EAU92072.2 - 3.6e-06 27.5 0.1 7.5e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EAU92072.2 - 0.029 14.2 0.1 0.034 14.0 0.1 1.3 1 1 0 1 1 1 0 Matrixin Tyrosinase PF00264.20 EAU92074.2 - 1.8e-29 103.6 4.2 3.2e-29 102.8 4.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-MYND PF01753.18 EAU92074.2 - 7.1e-08 32.4 11.7 1.7e-07 31.2 11.7 1.6 1 0 0 1 1 1 1 MYND finger Tyrosinase PF00264.20 EAU92075.1 - 6.4e-31 108.4 10.2 6.7e-31 108.3 9.1 1.5 1 1 1 2 2 2 1 Common central domain of tyrosinase Cmc1 PF08583.10 EAU92076.2 - 0.022 14.8 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Gpr1_Fun34_YaaH PF01184.19 EAU92077.1 - 2e-42 145.1 13.8 2.3e-42 144.9 13.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BTB PF00651.31 EAU92079.1 - 0.0046 17.2 0.2 0.023 14.9 0.2 2.0 1 1 0 1 1 1 1 BTB/POZ domain LisH_TPL PF17814.1 EAU92079.1 - 0.014 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 LisH-like dimerisation domain DUF4335 PF14233.6 EAU92079.1 - 0.029 14.3 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Cu-oxidase PF00394.22 EAU92088.2 - 8.3e-44 149.5 0.0 6.3e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU92088.2 - 4.3e-35 120.4 1.4 4e-33 114.1 0.0 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU92088.2 - 9.9e-32 109.5 0.1 2.8e-31 108.0 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EAU92090.2 - 5.6e-44 150.1 0.0 4.3e-42 143.9 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU92090.2 - 7.5e-37 126.0 0.1 2.4e-36 124.4 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU92090.2 - 9.5e-36 122.5 3.2 4.6e-34 117.1 0.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase zf-C2H2 PF00096.26 EAU92092.1 - 1e-05 25.7 0.8 0.021 15.2 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU92092.1 - 9.1e-05 23.0 1.0 0.15 13.0 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU92092.1 - 0.0092 16.3 0.3 0.1 12.9 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EAU92092.1 - 0.09 13.1 1.6 0.53 10.6 1.6 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Cu-oxidase PF00394.22 EAU92093.2 - 6e-50 169.5 0.0 3.4e-47 160.5 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU92093.2 - 5.4e-38 129.8 0.6 2.2e-36 124.6 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU92093.2 - 1.1e-25 90.0 0.1 2.4e-23 82.4 0.0 3.4 3 0 0 3 3 3 1 Multicopper oxidase ICMT PF04140.14 EAU92095.1 - 9.8e-12 45.1 0.3 3.4e-11 43.4 0.2 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EAU92095.1 - 1.1e-11 45.0 0.4 8.7e-10 38.9 0.4 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EAU92095.1 - 5.3e-05 22.1 0.7 7.9e-05 21.6 0.7 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1996 PF09362.10 EAU92096.2 - 3.4e-79 266.2 0.0 4.1e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pkinase_fungal PF17667.1 EAU92097.2 - 1.5e-25 89.8 0.0 1.7e-16 60.1 0.0 2.9 2 1 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EAU92097.2 - 0.0087 16.0 0.1 0.022 14.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EAU92097.2 - 0.019 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Glyco_transf_15 PF01793.16 EAU92099.2 - 4.5e-49 167.5 1.9 2.4e-33 115.7 0.0 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase DUF512 PF04459.12 EAU92099.2 - 0.021 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) PADR1 PF08063.12 EAU92101.2 - 0.18 11.6 5.6 8 6.3 0.1 2.9 3 0 0 3 3 3 0 PADR1 (NUC008) domain Abhydrolase_1 PF00561.20 EAU92103.2 - 2.8e-21 76.3 0.0 2.1e-19 70.2 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU92103.2 - 4.8e-21 76.4 2.7 5.8e-21 76.1 2.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU92103.2 - 6e-15 55.2 0.0 2.5e-10 40.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EAU92103.2 - 3.6e-06 26.8 0.0 0.027 14.2 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ndr PF03096.14 EAU92103.2 - 5.5e-06 25.3 0.0 9.2e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family FSH1 PF03959.13 EAU92103.2 - 0.091 12.4 0.0 2.3 7.8 0.0 2.4 3 0 0 3 3 3 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 EAU92103.2 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) CFEM PF05730.11 EAU92108.1 - 5e-07 29.7 10.6 8.3e-07 29.0 10.6 1.3 1 0 0 1 1 1 1 CFEM domain F-box-like PF12937.7 EAU92111.1 - 4.2e-10 39.4 0.1 8.2e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 EAU92111.1 - 0.025 14.5 0.8 6.6 6.7 0.1 2.7 2 0 0 2 2 2 0 F-box domain DUF1996 PF09362.10 EAU92114.1 - 4.7e-80 269.0 0.0 5.9e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EAU92114.1 - 1.6e-11 43.9 12.5 1.6e-11 43.9 12.5 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain F-box-like PF12937.7 EAU92117.2 - 0.00022 21.1 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 F-box-like EI24 PF07264.11 EAU92120.2 - 7.5e-06 26.3 6.8 1.6e-05 25.3 6.8 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AhpC-TSA_2 PF13911.6 EAU92121.2 - 1.3e-21 76.8 0.0 2.1e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EAU92121.2 - 5e-07 29.7 0.0 6.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EAU92121.2 - 1.4e-06 28.1 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.12 EAU92121.2 - 3e-05 23.7 0.0 4.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) DUF1981 PF09324.10 EAU92122.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) DUF1930 PF09122.10 EAU92123.2 - 0.055 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) DUF3678 PF12435.8 EAU92123.2 - 1 8.8 6.8 0.4 10.1 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) F-box-like PF12937.7 EAU92128.1 - 0.00062 19.6 0.0 0.0037 17.1 0.0 2.3 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU92128.1 - 0.24 11.9 3.8 15 6.2 0.2 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Dus PF01207.17 EAU92129.1 - 6e-75 252.2 0.0 9.4e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 EAU92129.1 - 8e-05 22.1 0.1 0.00017 21.0 0.0 1.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 EAU92129.1 - 0.0005 19.9 1.8 0.0025 17.6 0.0 2.7 2 1 1 3 3 3 1 SOR/SNZ family DLIC PF05783.11 EAU92129.1 - 0.12 11.2 0.0 1.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DNA_methylase PF00145.17 EAU92130.2 - 0.19 11.1 9.5 0.2 10.9 9.5 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase eIF-3_zeta PF05091.12 EAU92130.2 - 5.6 5.8 17.2 6.1 5.7 17.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Asp-B-Hydro_N PF05279.11 EAU92130.2 - 9.2 6.2 29.0 13 5.8 29.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.19 EAU92132.2 - 0.2 9.5 5.8 0.26 9.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tetraspanin PF00335.20 EAU92135.1 - 7e-11 42.3 7.0 9.2e-11 41.9 7.0 1.2 1 0 0 1 1 1 1 Tetraspanin family SLATT_5 PF18160.1 EAU92135.1 - 0.79 9.0 3.3 1 8.6 2.5 1.6 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 MARVEL PF01284.23 EAU92136.1 - 1.4e-07 31.6 11.0 1.4e-07 31.6 11.0 2.2 1 1 1 2 2 2 1 Membrane-associating domain Claudin_3 PF06653.11 EAU92136.1 - 0.028 14.4 1.2 0.028 14.4 1.2 2.1 2 0 0 2 2 2 0 Tight junction protein, Claudin-like TMEM101 PF15111.6 EAU92136.1 - 0.045 13.3 1.0 0.081 12.5 1.0 1.3 1 0 0 1 1 1 0 TMEM101 protein family Cpn60_TCP1 PF00118.24 EAU92138.2 - 3.8e-145 484.3 5.6 4.6e-145 484.0 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F-box-like PF12937.7 EAU92139.1 - 7.8e-06 25.7 0.1 0.00015 21.5 0.0 3.2 3 1 0 3 3 3 1 F-box-like F-box-like PF12937.7 EAU92140.2 - 0.0065 16.4 0.4 0.03 14.2 0.3 2.2 2 0 0 2 2 2 1 F-box-like SUR7 PF06687.12 EAU92141.2 - 0.081 12.5 0.2 0.081 12.5 0.2 2.6 2 1 0 2 2 2 0 SUR7/PalI family GMC_oxred_N PF00732.19 EAU92145.2 - 1.6e-46 159.1 0.9 1.8e-45 155.6 0.9 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EAU92145.2 - 1.2e-31 110.2 0.0 2.8e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase CBM_21 PF03370.13 EAU92149.1 - 2.1e-17 63.3 0.2 3.6e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EAU92149.1 - 0.0019 18.8 0.3 1.1 9.9 0.0 2.8 2 0 0 2 2 2 2 Starch/carbohydrate-binding module (family 53) 2OG-FeII_Oxy PF03171.20 EAU92150.1 - 3.1e-16 59.7 0.0 5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EAU92150.1 - 7.9e-16 58.9 0.0 1.3e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Bestrophin PF01062.21 EAU92151.2 - 7.2e-35 120.8 0.3 8.7e-19 68.0 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4598 PF15370.6 EAU92152.2 - 3.1e-13 50.1 16.8 1.3e-12 48.2 13.8 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Peptidase_S64 PF08192.11 EAU92152.2 - 0.019 13.5 5.5 0.018 13.6 5.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 PI3K_1B_p101 PF10486.9 EAU92152.2 - 0.048 11.5 7.6 0.047 11.5 7.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EAU92152.2 - 0.062 11.9 6.0 0.065 11.8 6.0 1.2 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 EAU92152.2 - 0.067 11.4 9.2 0.081 11.1 9.2 1.2 1 0 0 1 1 1 0 Nop14-like family AF-4 PF05110.13 EAU92152.2 - 0.12 10.5 19.9 0.14 10.2 19.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 EAU92152.2 - 0.15 10.3 10.5 0.18 10.0 10.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Presenilin PF01080.17 EAU92152.2 - 1 8.0 3.9 1.4 7.6 3.9 1.3 1 0 0 1 1 1 0 Presenilin Pacs-1 PF10254.9 EAU92152.2 - 1.5 7.7 7.8 0.39 9.6 3.9 1.7 1 1 0 2 2 2 0 PACS-1 cytosolic sorting protein DUF4614 PF15391.6 EAU92152.2 - 2.7 8.0 17.1 5.8 6.9 17.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DNA_pol_phi PF04931.13 EAU92152.2 - 6.3 4.8 14.0 9.6 4.2 14.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C14 PF00656.22 EAU92153.2 - 1.4e-45 156.2 0.6 3.3e-45 155.0 0.6 1.5 1 1 0 1 1 1 1 Caspase domain Roughex PF06020.11 EAU92153.2 - 1.4 7.9 10.1 2.9 6.9 10.1 1.5 1 0 0 1 1 1 0 Drosophila roughex protein TauD PF02668.16 EAU92154.1 - 9.7e-31 107.5 0.0 1.5e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EAU92154.1 - 0.022 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 CsiD zf-BED PF02892.15 EAU92156.2 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger F-box PF00646.33 EAU92157.2 - 1.3e-08 34.5 0.6 2.8e-08 33.4 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92157.2 - 2.2e-06 27.5 1.8 5.6e-06 26.2 1.8 1.8 1 0 0 1 1 1 1 F-box-like 60KD_IMP PF02096.20 EAU92158.2 - 0.18 11.7 2.5 0.21 11.5 0.6 1.8 1 1 1 2 2 2 0 60Kd inner membrane protein DUF3040 PF11239.8 EAU92158.2 - 0.21 11.8 1.9 0.44 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF983 PF06170.12 EAU92158.2 - 1.5 9.3 8.6 1.4 9.4 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Stevor PF17410.2 EAU92159.2 - 0.23 10.9 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF1180 PF06679.12 EAU92159.2 - 0.51 10.8 6.0 0.046 14.2 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CDP-OH_P_transf PF01066.21 EAU92160.1 - 3.5e-17 62.9 0.0 3.5e-17 62.9 0.0 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gasdermin PF04598.12 EAU92161.1 - 0.0097 15.3 1.5 0.014 14.8 1.5 1.2 1 0 0 1 1 1 1 Gasdermin pore forming domain Ndc1_Nup PF09531.10 EAU92161.1 - 0.018 13.7 4.9 0.024 13.3 4.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med3 PF11593.8 EAU92161.1 - 3.1 6.9 10.2 5.5 6.1 10.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box PF00646.33 EAU92162.2 - 0.0016 18.2 5.6 0.0027 17.5 1.1 2.7 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EAU92162.2 - 0.019 14.9 1.1 0.079 12.8 0.2 2.3 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 EAU92162.2 - 1.2 9.1 11.4 1.2 9.1 2.0 2.8 2 1 0 2 2 2 0 F-box-like F-box PF00646.33 EAU92163.2 - 5.2e-05 23.0 0.6 0.0001 22.1 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92163.2 - 0.013 15.4 2.2 0.025 14.5 2.2 1.5 1 0 0 1 1 1 0 F-box-like Big_8 PF17961.1 EAU92164.2 - 0.033 14.3 0.1 0.066 13.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig domain MARVEL PF01284.23 EAU92165.1 - 5.6e-09 36.2 21.2 6.7e-09 35.9 21.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Frag1 PF10277.9 EAU92165.1 - 0.01 15.4 11.8 0.01 15.4 11.8 2.2 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family Lipase_GDSL_2 PF13472.6 EAU92167.1 - 5.9e-25 88.7 2.0 1e-24 87.9 2.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU92167.1 - 1.4e-15 57.9 0.8 2e-15 57.3 0.8 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.18 EAU92167.1 - 9.1e-15 54.3 9.9 9.1e-15 54.3 9.9 1.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL_3 PF14606.6 EAU92167.1 - 0.001 19.3 0.0 0.0026 17.9 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 EAU92167.1 - 0.058 12.6 0.1 0.17 11.1 0.1 1.6 1 1 0 1 1 1 0 OSK domain PelD_GGDEF PF16963.5 EAU92167.1 - 0.069 13.0 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 PelD GGDEF domain Abhydrolase_6 PF12697.7 EAU92171.2 - 8.8e-06 26.5 0.0 1.6e-05 25.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Forkhead PF00250.18 EAU92171.2 - 0.044 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Forkhead domain F-box-like PF12937.7 EAU92172.2 - 0.00013 21.8 0.9 0.00029 20.6 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92172.2 - 0.0013 18.6 1.2 0.0027 17.5 1.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92173.2 - 2.6e-05 24.0 3.0 4.9e-05 23.1 3.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92173.2 - 0.005 16.7 0.6 0.01 15.7 0.6 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_C14 PF00656.22 EAU92175.2 - 1.8e-55 188.6 0.0 2.3e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Histone PF00125.24 EAU92176.1 - 1.2e-49 168.0 4.2 1.3e-49 167.9 4.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EAU92176.1 - 2.4e-05 24.6 0.1 4.1e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAU92176.1 - 9.3e-05 22.5 1.3 9.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EAU92176.1 - 0.00061 20.0 1.2 0.0014 18.9 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 EAU92176.1 - 0.0015 19.1 2.0 0.0019 18.8 2.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 EAU92176.1 - 0.084 12.9 0.2 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EAU92176.1 - 0.084 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated F-box-like PF12937.7 EAU92178.2 - 1.5e-05 24.8 2.1 3.1e-05 23.8 2.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92178.2 - 5.5e-05 22.9 2.5 0.00014 21.6 2.5 1.7 1 0 0 1 1 1 1 F-box domain Kelch_2 PF07646.15 EAU92179.1 - 0.0039 17.1 4.4 2.7e+02 1.8 0.0 7.3 9 0 0 9 9 9 0 Kelch motif DUF5122 PF17164.4 EAU92179.1 - 0.031 14.5 11.3 1.7e+02 2.6 0.0 7.3 8 0 0 8 8 8 0 Domain of unknown function (DUF5122) beta-propeller HCV_NS5a_1a PF08300.13 EAU92179.1 - 0.19 11.9 4.1 84 3.4 0.1 4.6 1 1 7 8 8 8 0 Hepatitis C virus non-structural 5a zinc finger domain DUF2997 PF11211.8 EAU92179.1 - 0.27 11.0 1.0 1.3e+02 2.5 0.0 4.7 7 0 0 7 7 7 0 Protein of unknown function (DUF2997) HtaA PF04213.13 EAU92179.1 - 0.4 11.2 6.0 1.1e+02 3.3 4.1 3.6 1 1 1 2 2 2 0 Htaa Arteri_Gl PF00951.18 EAU92179.1 - 0.6 9.9 1.6 98 2.7 0.0 3.3 1 1 2 4 4 4 0 Arterivirus GL envelope glycoprotein DUF903 PF06004.12 EAU92179.1 - 0.96 9.4 12.3 1.4e+02 2.4 0.0 7.6 10 0 0 10 10 10 0 Bacterial protein of unknown function (DUF903) Dockerin_1 PF00404.18 EAU92179.1 - 2 8.7 13.8 40 4.5 1.5 5.8 1 1 3 4 4 4 0 Dockerin type I domain F-box-like PF12937.7 EAU92183.1 - 7e-07 29.0 0.1 1.7e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92183.1 - 0.03 14.2 0.5 0.03 14.2 0.5 3.0 3 1 0 3 3 3 0 F-box domain HlyC PF02794.16 EAU92184.1 - 0.026 14.4 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 RTX toxin acyltransferase family DUF2992 PF11208.8 EAU92184.1 - 0.034 14.4 7.2 0.16 12.2 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Topo-VIb_trans PF09239.11 EAU92184.1 - 0.27 11.0 1.7 0.83 9.5 1.2 2.0 2 1 0 2 2 2 0 Topoisomerase VI B subunit, transducer DUF4710 PF15828.5 EAU92184.1 - 1.3 9.2 6.1 0.2 11.8 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF4110 PF13422.6 EAU92184.1 - 5.4 7.2 8.0 2 8.6 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) SDP_N PF12278.8 EAU92184.1 - 7.9 6.6 9.9 6.5 6.9 2.6 2.4 2 0 0 2 2 2 0 Sex determination protein N terminal F-box PF00646.33 EAU92192.2 - 0.058 13.3 4.6 0.17 11.8 4.6 1.9 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 EAU92192.2 - 9.1 6.3 7.3 0.6 10.0 1.5 2.2 3 0 0 3 3 3 0 F-box-like Rod-binding PF10135.9 EAU92197.1 - 0.038 14.6 0.7 0.038 14.6 0.7 1.9 2 1 0 2 2 2 0 Rod binding protein Ribosomal_L1 PF00687.21 EAU92198.2 - 1.5e-47 162.0 2.0 1.8e-47 161.8 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WSC PF01822.19 EAU92199.2 - 1.5e-39 134.1 19.5 1.4e-19 70.0 7.5 2.2 2 0 0 2 2 2 2 WSC domain Amidohydro_2 PF04909.14 EAU92202.2 - 0.0084 15.9 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Cauli_VI PF01693.16 EAU92203.1 - 7.9e-13 48.5 0.0 1.4e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin F-box PF00646.33 EAU92205.1 - 0.0002 21.1 0.5 0.00045 20.0 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92205.1 - 0.00024 20.9 1.1 0.00054 19.8 1.1 1.6 1 0 0 1 1 1 1 F-box-like DUF676 PF05057.14 EAU92207.2 - 0.014 14.9 0.0 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.12 EAU92207.2 - 0.035 13.6 0.0 0.079 12.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PE-PPE PF08237.11 EAU92207.2 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain CBM_21 PF03370.13 EAU92208.2 - 1.8e-22 79.7 0.0 3.1e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EAU92208.2 - 3.2e-06 27.6 0.1 7.3e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Peptidase_M17 PF00883.21 EAU92210.2 - 2.5e-115 385.1 0.0 3.2e-115 384.7 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EAU92210.2 - 6.2e-09 35.8 0.1 1.1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain CSTF2_hinge PF14327.6 EAU92212.2 - 1.4e-07 31.8 2.8 1.4e-07 31.8 2.8 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 EAU92212.2 - 8e-07 28.5 0.2 2.1e-06 27.2 0.2 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF726 PF05277.12 EAU92213.2 - 9.5e-115 383.2 1.2 9.5e-115 383.2 1.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF726) DUF3541 PF12060.8 EAU92213.2 - 0.011 15.4 0.7 0.019 14.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) VirJ PF06057.11 EAU92213.2 - 0.15 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Herpes_UL56 PF04534.12 EAU92215.1 - 0.0024 17.4 0.7 0.0044 16.5 0.2 1.6 1 1 0 1 1 1 1 Herpesvirus UL56 protein SRP14 PF02290.15 EAU92216.1 - 4e-26 91.2 0.7 8.7e-26 90.1 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF1266 PF06889.11 EAU92216.1 - 1.7 8.7 5.2 4.8 7.2 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) TP_methylase PF00590.20 EAU92217.1 - 4e-42 144.6 0.4 6.6e-42 143.8 0.4 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EAU92217.1 - 6.1e-14 52.3 0.0 1.2e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EAU92217.1 - 2.6e-09 36.6 0.2 1.6e-07 30.9 0.1 2.4 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EAU92217.1 - 4.9e-09 35.5 0.0 1.3e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Yop-YscD_cpl PF16697.5 EAU92217.1 - 0.18 12.1 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF3328 PF11807.8 EAU92218.2 - 5.5e-17 62.3 0.1 7.3e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pox_A14 PF05767.12 EAU92219.1 - 3.3 7.9 7.5 0.19 11.9 0.6 2.5 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Cohesin_load PF10345.9 EAU92222.1 - 2.1e-06 26.5 0.0 0.16 10.4 0.0 3.1 3 0 0 3 3 3 3 Cohesin loading factor FAT PF02259.23 EAU92222.1 - 0.12 11.6 0.4 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 FAT domain TPR_12 PF13424.6 EAU92222.1 - 1.3 9.4 8.6 13 6.1 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat OTT_1508_deam PF14441.6 EAU92223.2 - 2e-15 56.6 0.0 4.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase IRF PF00605.17 EAU92223.2 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor ubiquitin PF00240.23 EAU92224.1 - 1.5e-34 117.6 0.5 1.9e-34 117.2 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EAU92224.1 - 5.1e-30 103.1 8.9 7.7e-30 102.5 8.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EAU92224.1 - 2.9e-16 59.0 0.6 4.5e-16 58.4 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAU92224.1 - 2.1e-05 24.9 0.1 7.7e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EAU92224.1 - 0.0048 16.8 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAU92224.1 - 0.0054 17.1 0.0 0.0084 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAU92224.1 - 0.0075 16.4 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EAU92224.1 - 0.014 15.4 1.1 4 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EAU92224.1 - 0.027 15.0 0.1 0.033 14.7 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain MdcG PF10620.9 EAU92225.1 - 0.024 14.5 0.3 0.046 13.5 0.3 1.4 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG TFIIA PF03153.13 EAU92225.1 - 0.072 13.1 3.5 0.13 12.3 3.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EAU92225.1 - 7.6 4.6 6.5 11 4.1 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family COX5A PF02284.16 EAU92226.1 - 9e-42 141.3 0.4 1.2e-41 140.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4817 PF16087.5 EAU92226.1 - 0.035 13.9 0.0 0.18 11.7 0.0 2.2 1 1 2 3 3 3 0 Helix-turn-helix domain (DUF4817) NTS PF15447.6 EAU92226.1 - 0.17 12.4 1.0 0.27 11.8 1.0 1.3 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 bZIP_2 PF07716.15 EAU92227.1 - 2.1e-07 30.9 13.0 4e-07 30.0 13.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EAU92227.1 - 1.8e-05 24.7 11.3 3e-05 24.0 11.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EAU92227.1 - 0.017 15.6 6.9 0.017 15.6 6.9 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Uds1 PF15456.6 EAU92227.1 - 0.28 11.3 9.6 0.5 10.5 9.6 1.6 1 1 0 1 1 1 0 Up-regulated During Septation OTT_1508_deam PF14441.6 EAU92228.2 - 3.3e-14 52.7 0.0 5.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase F-box-like PF12937.7 EAU92229.2 - 0.019 14.8 2.8 0.039 13.8 2.8 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EAU92229.2 - 0.049 13.5 2.2 0.11 12.4 2.2 1.6 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 EAU92229.2 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 EAU92231.2 - 5e-74 249.0 0.0 6.6e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92231.2 - 1.6e-39 135.7 0.0 2.4e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EAU92231.2 - 1.5e-16 60.9 2.1 6.3e-11 42.8 0.1 3.4 2 1 1 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EAU92231.2 - 1.6e-13 50.5 0.1 3.2e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 EAU92231.2 - 3e-05 23.7 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EAU92231.2 - 6.5e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAU92231.2 - 0.0003 19.9 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EAU92231.2 - 0.0033 16.8 0.6 0.062 12.6 0.6 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EAU92231.2 - 0.068 12.0 0.1 0.099 11.5 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 EAU92231.2 - 0.15 12.0 2.5 0.2 11.5 0.3 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family SUIM_assoc PF16619.5 EAU92232.1 - 0.00028 20.9 0.0 0.0024 17.9 0.0 2.4 2 1 1 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TM231 PF10149.9 EAU92232.1 - 0.013 14.8 0.5 0.013 14.8 0.5 1.6 2 0 0 2 2 2 0 Transmembrane protein 231 Neur_chan_memb PF02932.16 EAU92232.1 - 0.29 11.2 1.8 0.35 10.9 1.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region F-box PF00646.33 EAU92233.2 - 1.9e-05 24.4 0.9 3.9e-05 23.4 0.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92233.2 - 0.00034 20.5 0.1 0.00069 19.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF3328 PF11807.8 EAU92235.2 - 3.8e-18 66.1 6.9 3.1e-17 63.1 6.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Sex_peptide PF08138.11 EAU92235.2 - 0.0016 18.5 0.2 12 6.1 0.3 3.5 3 0 0 3 3 3 3 Sex peptide (SP) family F-box-like PF12937.7 EAU92236.2 - 5.7e-07 29.3 2.7 1.1e-06 28.4 2.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92236.2 - 1.8e-05 24.5 1.6 3.8e-05 23.5 1.6 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EAU92236.2 - 0.095 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box NIPSNAP PF07978.13 EAU92237.2 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 NIPSNAP DUF1949 PF09186.11 EAU92237.2 - 0.11 12.4 0.6 0.55 10.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) KDZ PF18758.1 EAU92238.2 - 1.4e-34 119.7 0.0 2.8e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DMSP_lyase PF16867.5 EAU92239.1 - 0.031 13.9 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase DUF1640 PF07798.11 EAU92239.1 - 0.089 12.8 2.2 0.12 12.4 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Vps54_N PF10475.9 EAU92241.2 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex KDZ PF18758.1 EAU92244.2 - 1.3e-44 152.5 0.0 2.2e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU92244.2 - 1.4e-23 83.1 0.3 3.2e-23 81.9 0.3 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU92244.2 - 0.026 14.7 0.1 0.059 13.5 0.1 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases SH3-RhoG_link PF16609.5 EAU92251.1 - 0.0012 18.6 0.3 0.0028 17.4 0.1 1.6 2 0 0 2 2 2 1 SH3-RhoGEF linking unstructured region DASH_Dam1 PF08653.10 EAU92251.1 - 0.017 14.9 0.7 0.033 14.0 0.1 1.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 EFG_IV PF03764.18 EAU92251.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G, domain IV KDZ PF18758.1 EAU92252.2 - 2.6e-08 33.8 0.0 4.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU92252.2 - 0.0031 17.6 0.0 0.0054 16.9 0.0 1.3 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases HLH PF00010.26 EAU92254.2 - 5e-10 39.2 5.8 1e-09 38.2 3.0 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1192 PF06698.11 EAU92254.2 - 0.0045 17.0 0.6 0.012 15.6 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF4482 PF14818.6 EAU92254.2 - 0.01 16.7 0.2 0.061 14.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) TolA_bind_tri PF16331.5 EAU92254.2 - 0.017 15.2 0.5 0.017 15.2 0.5 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation FapA PF03961.13 EAU92254.2 - 0.019 13.6 1.4 0.026 13.2 1.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFP_35_N PF07334.13 EAU92254.2 - 0.092 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DASH_Dam1 PF08653.10 EAU92254.2 - 0.19 11.6 0.3 0.48 10.3 0.2 1.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 DivIC PF04977.15 EAU92254.2 - 0.46 10.3 7.4 0.14 11.9 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 EAU92254.2 - 2.9 8.4 7.2 7 7.2 7.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2919 PF11143.8 EAU92255.2 - 0.0018 18.6 2.3 0.0093 16.3 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2919) DUF4234 PF14018.6 EAU92255.2 - 0.038 14.1 0.0 0.038 14.1 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) MASE2 PF05230.11 EAU92255.2 - 0.08 13.0 3.1 0.091 12.8 1.7 1.8 2 0 0 2 2 2 0 MASE2 domain Exonuc_VIII PF06630.11 EAU92255.2 - 0.18 11.6 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII HLH PF00010.26 EAU92256.1 - 4.8e-11 42.4 1.4 4.8e-11 42.4 1.4 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TBCA PF02970.16 EAU92258.2 - 6.9e-25 87.2 2.8 8.6e-25 86.9 2.8 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Med11 PF10280.9 EAU92259.1 - 0.015 15.7 1.2 0.039 14.4 0.0 1.9 1 1 1 2 2 2 0 Mediator complex protein Het-C PF07217.11 EAU92260.1 - 5.6e-220 731.6 0.0 8.6e-220 731.0 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C LTV PF04180.14 EAU92261.1 - 5.6e-101 339.0 14.0 6.4e-93 312.5 16.0 2.1 1 1 1 2 2 2 2 Low temperature viability protein Bromodomain PF00439.25 EAU92262.2 - 8.2e-53 176.4 0.0 3.8e-17 62.1 0.1 3.7 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 EAU92262.2 - 2.5e-09 37.0 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain MRP-L28 PF09812.9 EAU92263.1 - 7.4e-09 35.9 5.2 3e-08 34.0 2.5 2.2 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L28 ARA70 PF12489.8 EAU92263.1 - 0.045 13.9 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear coactivator PhoU PF01895.19 EAU92263.1 - 0.057 13.9 1.4 0.15 12.5 1.5 1.7 2 1 0 2 2 2 0 PhoU domain PCI PF01399.27 EAU92264.2 - 1.4e-20 73.8 0.2 3.8e-20 72.3 0.2 1.8 1 0 0 1 1 1 1 PCI domain DUF5517 PF17639.2 EAU92264.2 - 0.25 11.7 7.0 1.9 8.8 1.5 3.5 3 1 0 3 3 3 0 Family of unknown function (DUF5517) Rsm22 PF09243.10 EAU92266.1 - 1.8e-42 145.5 0.1 1.4e-27 96.6 0.0 3.2 3 1 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.29 EAU92267.2 - 4e-26 92.1 0.0 5.3e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EAU92267.2 - 2.3e-11 43.8 0.2 4e-11 43.1 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 EAU92267.2 - 0.48 10.2 1.7 0.84 9.4 0.5 1.9 2 0 0 2 2 2 0 Variant UBP zinc finger WD40 PF00400.32 EAU92269.2 - 4.7e-40 134.9 20.1 1.3e-07 32.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU92269.2 - 1.6e-15 57.2 0.0 0.0047 17.2 0.1 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EAU92269.2 - 0.0021 18.0 0.0 1.2 8.9 0.0 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EAU92269.2 - 0.0039 16.2 1.3 7.2 5.5 0.0 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EAU92269.2 - 0.0049 16.2 0.0 0.97 8.7 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 EAU92269.2 - 0.14 10.7 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Tropomyosin PF00261.20 EAU92270.1 - 7.9e-05 22.1 38.4 7.9e-05 22.1 38.4 5.3 1 1 2 4 4 4 2 Tropomyosin ATG16 PF08614.11 EAU92270.1 - 0.00022 21.5 150.5 0.021 15.1 30.8 7.7 2 1 5 8 8 8 4 Autophagy protein 16 (ATG16) BRE1 PF08647.11 EAU92270.1 - 0.00027 21.0 9.8 0.00027 21.0 9.8 9.0 5 2 2 8 8 8 1 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 EAU92270.1 - 0.00086 19.4 10.5 0.00086 19.4 10.5 8.1 2 1 5 7 7 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 EAU92270.1 - 0.0015 19.1 12.2 0.0015 19.1 12.2 9.1 1 1 7 8 8 7 2 Clathrin-binding domain of Huntingtin-interacting protein 1 ERM PF00769.19 EAU92270.1 - 0.0022 17.9 25.5 0.0022 17.9 25.5 5.9 2 1 3 5 5 4 1 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 EAU92270.1 - 0.0089 16.3 16.7 0.0089 16.3 16.7 7.2 2 2 5 7 7 7 1 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EAU92270.1 - 0.018 15.6 21.1 0.018 15.6 21.1 7.8 1 1 7 8 8 7 0 Apg6 coiled-coil region Spc29 PF17082.5 EAU92270.1 - 0.031 14.1 0.1 0.031 14.1 0.1 6.8 1 1 5 6 6 6 0 Spindle Pole Component 29 SlyX PF04102.12 EAU92270.1 - 0.055 14.1 0.6 0.055 14.1 0.6 11.9 3 1 9 12 12 12 0 SlyX Filament PF00038.21 EAU92270.1 - 0.08 12.5 111.7 0.6 9.6 14.5 5.8 2 1 3 5 5 5 0 Intermediate filament protein Spc7 PF08317.11 EAU92270.1 - 0.088 11.7 126.5 0.04 12.8 14.9 5.9 1 1 4 6 6 6 0 Spc7 kinetochore protein Mce4_CUP1 PF11887.8 EAU92270.1 - 0.53 9.7 26.0 0.047 13.1 5.2 4.6 3 1 0 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF4686 PF15742.5 EAU92270.1 - 0.96 8.5 125.9 1.1 8.3 55.8 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4686) TACC_C PF05010.14 EAU92270.1 - 2.9 7.6 99.7 1.5 8.5 27.9 4.9 2 1 3 5 5 5 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Myosin_tail_1 PF01576.19 EAU92270.1 - 3.7 5.2 126.7 1.1 6.9 100.2 2.6 1 1 1 2 2 2 0 Myosin tail AAA_13 PF13166.6 EAU92270.1 - 4.2 5.9 91.7 3.7 6.1 28.4 3.8 1 1 2 3 3 3 0 AAA domain polyprenyl_synt PF00348.17 EAU92273.2 - 3.2e-34 118.1 0.0 9.2e-30 103.5 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase DUF543 PF04418.12 EAU92273.2 - 0.15 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF543) HEPPP_synt_1 PF07307.11 EAU92273.2 - 0.22 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RRM_1 PF00076.22 EAU92275.2 - 5.4e-17 61.4 0.0 1.6e-11 43.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EAU92275.2 - 0.00081 19.3 0.1 0.55 10.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EAU92275.2 - 0.022 14.4 0.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EAU92275.2 - 0.28 11.0 0.0 1.8 8.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Ras PF00071.22 EAU92276.2 - 2.7e-60 202.7 0.1 3.1e-60 202.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU92276.2 - 1.1e-36 125.7 0.0 1.6e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU92276.2 - 1.4e-14 53.9 0.1 1.7e-14 53.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EAU92276.2 - 8.2e-07 29.1 0.3 0.0056 16.6 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EAU92276.2 - 1e-06 28.5 0.0 1.8e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAU92276.2 - 5.2e-06 26.5 0.0 7.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAU92276.2 - 7.7e-06 25.4 0.0 9.3e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EAU92276.2 - 0.0048 17.3 0.2 0.0089 16.4 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EAU92276.2 - 0.083 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin TniB PF05621.11 EAU92276.2 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein RasGEF PF00617.19 EAU92277.2 - 3e-42 144.8 0.3 5.1e-42 144.1 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAU92277.2 - 2.1e-18 66.5 0.0 4.7e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EAU92277.2 - 1.9e-11 43.3 0.1 3.8e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAU92277.2 - 5.8e-10 38.7 0.0 1.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EAU92277.2 - 9.6e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ist1 PF03398.14 EAU92278.2 - 8.6e-61 204.6 1.3 1.2e-60 204.2 1.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Indigoidine_A PF04227.12 EAU92278.2 - 0.13 11.6 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein HTH_23 PF13384.6 EAU92278.2 - 0.18 11.6 1.5 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Methyltransf_23 PF13489.6 EAU92279.1 - 7.4e-13 48.7 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU92279.1 - 1.1e-08 35.7 0.1 5.1e-08 33.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU92279.1 - 3.6e-08 33.9 0.0 1.3e-07 32.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU92279.1 - 1.1e-07 32.5 0.1 5.8e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU92279.1 - 2.5e-07 30.6 0.0 0.011 15.5 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.17 EAU92279.1 - 0.0017 17.8 0.0 0.044 13.2 0.0 2.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 EAU92279.1 - 0.0025 17.2 0.0 0.0053 16.1 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 EAU92279.1 - 0.042 14.0 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EAU92280.2 - 6.7e-13 48.8 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU92280.2 - 1.3e-11 44.6 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU92280.2 - 8.5e-11 42.4 0.0 1.6e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU92280.2 - 7.8e-10 39.4 0.0 1.5e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU92280.2 - 9e-10 39.1 0.0 1.8e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAU92280.2 - 7.2e-07 28.9 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EAU92280.2 - 8.6e-06 25.3 0.0 4.3e-05 23.0 0.0 2.1 3 0 0 3 3 3 1 Putative methyltransferase FtsJ PF01728.19 EAU92280.2 - 0.00053 20.1 0.0 0.00088 19.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EAU92280.2 - 0.0011 18.3 0.0 0.0026 17.1 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EAU92280.2 - 0.017 14.7 0.0 0.036 13.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EAU92280.2 - 0.023 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EAU92280.2 - 0.028 13.0 0.0 0.47 8.9 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.32 EAU92285.2 - 2.3e-20 72.5 14.5 0.0068 17.2 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EAU92285.2 - 0.015 13.9 3.9 15 4.0 0.0 4.1 3 1 1 4 4 4 0 Cytochrome D1 heme domain Nup160 PF11715.8 EAU92285.2 - 0.023 13.4 0.2 0.32 9.6 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.32 EAU92286.2 - 1.2e-21 76.5 8.7 2.6e-07 31.2 0.1 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU92286.2 - 9.6e-08 32.2 0.3 0.12 12.7 0.0 4.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU92286.2 - 0.013 14.5 0.3 2.5 7.0 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATF7IP_BD PF16788.5 EAU92286.2 - 8.9 6.3 8.9 14 5.7 8.9 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Bax1-I PF01027.20 EAU92287.2 - 5.2e-39 134.2 8.3 5.2e-39 134.2 8.3 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Sec1 PF00995.23 EAU92288.1 - 1.1e-122 411.2 0.0 1.4e-122 410.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family RSN1_7TM PF02714.15 EAU92289.2 - 3.3e-13 49.6 23.6 5.3e-13 48.9 23.6 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 EAU92289.2 - 3.6e-05 23.9 0.0 8.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PhzC-PhzF PF02567.16 EAU92291.1 - 3.3e-30 105.5 0.0 5.4e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF4246 PF14033.6 EAU92292.2 - 2.2e-74 251.2 0.0 2.8e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Rotamase PF00639.21 EAU92294.1 - 8.4e-22 78.0 0.0 1.1e-21 77.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EAU92294.1 - 9.3e-21 74.5 0.0 1.3e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EAU92294.1 - 8.8e-08 32.1 0.1 8.8e-08 32.1 0.1 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EAU92294.1 - 0.001 19.9 0.0 0.0014 19.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain NCBP3 PF10309.9 EAU92296.1 - 7.6e-08 32.1 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 EAU92296.1 - 2.1e-05 24.5 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain GTP_EFTU PF00009.27 EAU92297.1 - 6.3e-68 228.2 0.3 9e-68 227.6 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EAU92297.1 - 1.8e-33 114.9 0.0 9.2e-33 112.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EAU92297.1 - 9.1e-23 80.1 0.0 2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EAU92297.1 - 1.9e-13 50.3 0.0 6.5e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EAU92297.1 - 5.5e-13 49.1 0.0 1.7e-12 47.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAU92297.1 - 0.00013 22.1 0.1 0.00028 21.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EAU92297.1 - 0.039 13.7 0.4 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAD_binding_3 PF01494.19 EAU92298.1 - 7e-22 78.1 0.1 3.1e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EAU92298.1 - 8e-07 28.6 0.4 9.1e-06 25.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EAU92298.1 - 2.3e-05 24.5 0.3 7.1e-05 23.0 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EAU92298.1 - 0.00019 20.4 0.1 0.014 14.3 0.1 2.7 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EAU92298.1 - 0.00033 19.9 0.7 0.0006 19.0 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EAU92298.1 - 0.001 19.6 0.7 0.0026 18.3 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EAU92298.1 - 0.0035 16.6 1.5 0.0076 15.5 1.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EAU92298.1 - 0.007 16.0 3.1 0.0084 15.7 2.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EAU92298.1 - 0.0079 15.3 3.6 0.011 14.8 3.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EAU92298.1 - 0.0081 14.9 1.9 0.012 14.4 1.9 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EAU92298.1 - 0.0095 15.3 0.6 0.014 14.8 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EAU92298.1 - 0.033 13.2 1.4 1.6 7.7 0.5 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EAU92298.1 - 0.073 12.3 2.5 0.091 12.0 0.6 1.9 2 0 0 2 2 2 0 Thi4 family SE PF08491.10 EAU92298.1 - 0.088 11.8 0.1 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Acetyltransf_3 PF13302.7 EAU92299.1 - 7.5e-21 75.3 0.0 9.4e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU92299.1 - 4.6e-07 30.1 0.0 6.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EAU92299.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU92299.1 - 0.052 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 EAU92300.1 - 2.7e-19 70.2 0.0 3.5e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU92300.1 - 0.0032 17.7 0.0 0.0043 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SH3_1 PF00018.28 EAU92301.2 - 3.6e-11 42.5 0.1 6.2e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EAU92301.2 - 8.1e-09 35.0 0.0 1.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EAU92301.2 - 3.7e-07 29.9 0.0 6.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EAU92301.2 - 0.044 14.1 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain zf-C3HC4 PF00097.25 EAU92302.1 - 1.6e-09 37.4 7.5 3.3e-09 36.5 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU92302.1 - 4.8e-08 32.9 11.1 8.3e-07 28.9 11.1 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EAU92302.1 - 2.6e-07 30.8 10.0 4.7e-07 30.0 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EAU92302.1 - 3.8e-07 29.9 9.6 7.8e-07 28.8 9.1 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU92302.1 - 1e-06 28.5 5.8 1.7e-06 27.7 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EAU92302.1 - 2.1e-06 27.8 9.6 3.8e-06 27.0 9.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EAU92302.1 - 3.5e-06 26.9 6.9 6.4e-06 26.0 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EAU92302.1 - 0.0006 19.6 7.7 0.0022 17.8 8.1 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EAU92302.1 - 0.0016 18.7 5.3 0.0034 17.6 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EAU92302.1 - 0.006 16.6 3.1 0.011 15.7 3.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY_C PF15616.6 EAU92302.1 - 0.01 16.0 0.9 0.02 15.0 0.9 1.4 1 0 0 1 1 1 1 TerY-C metal binding domain zf-Nse PF11789.8 EAU92302.1 - 0.015 15.1 5.2 0.015 15.1 5.2 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit U79_P34 PF03064.16 EAU92302.1 - 2.5 7.4 6.1 0.19 11.0 0.7 1.8 2 0 0 2 2 2 0 HSV U79 / HCMV P34 zf-MIZ PF02891.20 EAU92302.1 - 3.8 7.3 8.0 8 6.3 8.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 EAU92302.1 - 4.6 7.1 11.5 2.3 8.1 4.3 2.7 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 EAU92302.1 - 4.9 7.4 6.6 12 6.1 6.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Wbp11 PF09429.10 EAU92303.2 - 4.5e-21 75.0 13.7 7.9e-21 74.3 13.7 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 EAU92303.2 - 5.2e-16 59.2 9.0 5.2e-16 59.2 9.0 8.9 3 1 2 5 5 5 1 mRNA biogenesis factor ABC_tran_CTD PF16326.5 EAU92303.2 - 0.036 14.3 8.6 0.067 13.5 8.6 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 EAU92303.2 - 3.1 8.1 5.1 35 4.7 5.1 2.4 1 1 0 1 1 1 0 Osmosensory transporter coiled coil ZT_dimer PF16916.5 EAU92304.2 - 5.2e-12 45.7 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 EAU92304.2 - 5.6e-10 39.3 2.1 2.1e-09 37.4 2.1 1.8 1 1 0 1 1 1 1 Cation efflux family UL45 PF05473.12 EAU92306.2 - 0.0084 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 UL45 protein, carbohydrate-binding C-type lectin-like MFS_1 PF07690.16 EAU92307.1 - 7.9e-21 74.4 16.5 1.3e-20 73.7 16.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cpn60_TCP1 PF00118.24 EAU92308.1 - 4.9e-154 513.6 0.1 5.5e-154 513.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 EAU92308.1 - 0.065 13.7 0.0 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch SNF2_N PF00176.23 EAU92309.2 - 2.2e-67 227.3 0.0 2.9e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU92309.2 - 4.5e-14 52.7 0.0 8.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EAU92309.2 - 2.3e-10 40.3 0.0 7.9e-10 38.5 0.0 1.9 2 0 0 2 2 1 1 HIRAN domain ResIII PF04851.15 EAU92309.2 - 5.2e-07 29.8 0.0 2.9e-06 27.4 0.0 2.3 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EAU92309.2 - 3.1e-06 27.0 12.6 5.5e-06 26.1 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU92309.2 - 4.7e-06 26.3 12.8 0.00011 22.0 12.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EAU92309.2 - 7.6e-06 25.8 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 EAU92309.2 - 8.5e-05 22.3 8.0 0.00014 21.6 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EAU92309.2 - 9.3e-05 22.7 11.8 0.00018 21.7 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU92309.2 - 0.00014 21.8 12.1 0.00031 20.7 11.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAU92309.2 - 0.00073 19.4 11.1 0.0012 18.7 11.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EAU92309.2 - 0.032 14.4 14.2 0.06 13.5 14.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EAU92309.2 - 0.083 12.7 7.8 0.18 11.6 7.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EAU92309.2 - 0.31 10.8 7.4 0.71 9.7 7.4 1.7 1 0 0 1 1 1 0 RING-like zinc finger SPAN-X PF07458.12 EAU92309.2 - 0.43 11.1 4.1 1.6 9.2 4.1 2.0 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome zf-ribbon_3 PF13248.6 EAU92309.2 - 2 7.9 5.4 0.33 10.4 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain NOA36 PF06524.12 EAU92309.2 - 2.3 7.5 7.0 0.063 12.6 0.4 1.7 2 0 0 2 2 1 0 NOA36 protein zf-MIZ PF02891.20 EAU92309.2 - 8 6.3 7.0 14 5.5 7.0 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RNase_H PF00075.24 EAU92310.2 - 4.7e-31 107.9 0.0 1.2e-30 106.5 0.0 1.7 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.16 EAU92310.2 - 5.4e-20 71.4 2.1 9.9e-20 70.6 2.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin SPX PF03105.19 EAU92310.2 - 0.41 10.5 10.0 0.7 9.7 10.0 1.5 1 0 0 1 1 1 0 SPX domain DUF1631 PF07793.11 EAU92310.2 - 5.1 5.4 9.4 8.5 4.7 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) F-box-like PF12937.7 EAU92311.1 - 2.3e-05 24.2 0.1 8.6e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EAU92311.1 - 0.029 14.3 0.2 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain SIKE PF05769.11 EAU92312.2 - 3.9e-10 39.9 24.0 1.7e-08 34.6 9.2 2.9 3 0 0 3 3 3 2 SIKE family NYD-SP28_assoc PF14775.6 EAU92312.2 - 0.15 12.2 18.2 0.28 11.3 2.4 3.6 3 1 0 3 3 3 0 Sperm tail C-terminal domain PikAIV_N PF18605.1 EAU92312.2 - 2.1 8.0 6.4 9 6.0 0.0 2.7 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain MCC-bdg_PDZ PF10506.9 EAU92312.2 - 4.3 7.4 10.5 2.4 8.3 1.3 3.0 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome YabA PF06156.13 EAU92312.2 - 6.8 7.4 20.4 2.7 8.7 0.1 4.0 3 1 2 5 5 5 0 Initiation control protein YabA Borrelia_P83 PF05262.11 EAU92315.2 - 6.2 5.2 7.3 12 4.2 7.3 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein BSP PF04450.12 EAU92318.2 - 1.4e-63 214.4 0.0 1.7e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 EAU92318.2 - 0.099 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 SprT-like family HLH PF00010.26 EAU92319.1 - 5.7e-06 26.2 0.0 9.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hamartin PF04388.12 EAU92319.1 - 0.72 8.4 9.0 0.87 8.2 9.0 1.1 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.10 EAU92319.1 - 1 8.0 7.4 1.2 7.8 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 EAU92319.1 - 3 7.4 9.9 4 7.0 9.9 1.2 1 0 0 1 1 1 0 Spt20 family F-box-like PF12937.7 EAU92321.2 - 0.029 14.2 0.1 0.081 12.8 0.1 1.8 1 0 0 1 1 1 0 F-box-like HSV_VP16_C PF12149.8 EAU92321.2 - 0.21 11.7 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal UCH PF00443.29 EAU92322.2 - 8.9e-43 146.6 0.0 1.4e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EAU92322.2 - 7.6e-21 75.0 0.3 1.4e-20 74.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EAU92322.2 - 0.04 13.4 1.0 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MOSC PF03473.17 EAU92323.1 - 3.3e-23 82.2 0.0 5.1e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EAU92323.1 - 3.2e-18 65.7 0.0 6.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Methyltransf_16 PF10294.9 EAU92324.2 - 9.3e-17 61.3 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FAM86 PF14904.6 EAU92324.2 - 0.0062 16.6 0.1 0.021 14.9 0.1 2.0 1 0 0 1 1 1 1 Family of unknown function Bot1p PF12298.8 EAU92325.1 - 3e-47 161.0 1.0 5.2e-47 160.2 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 EAU92325.1 - 0.034 14.3 0.0 0.034 14.3 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 F5_F8_type_C PF00754.25 EAU92326.1 - 1.3e-05 25.3 0.2 1.9e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 EAU92326.1 - 0.0042 16.7 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Sad1_UNC PF07738.13 EAU92326.1 - 0.0069 16.4 0.1 0.008 16.2 0.1 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1501 PF07394.12 EAU92326.1 - 0.16 11.0 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Y_phosphatase PF00102.27 EAU92327.1 - 2.8e-37 128.6 0.0 5.4e-22 78.5 0.0 2.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EAU92327.1 - 0.0032 17.6 0.0 0.0063 16.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate ADH_zinc_N PF00107.26 EAU92328.2 - 2e-25 89.2 0.1 3.2e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EAU92328.2 - 4.1e-16 60.2 0.0 8.6e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EAU92328.2 - 9.1e-05 22.3 0.0 0.0003 20.6 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PA PF02225.22 EAU92328.2 - 0.022 14.8 0.1 0.052 13.6 0.1 1.8 1 0 0 1 1 1 0 PA domain UCH PF00443.29 EAU92329.1 - 3.2e-39 135.0 0.0 7.9e-39 133.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EAU92329.1 - 2.3e-22 78.7 0.8 7.1e-18 64.3 0.1 2.7 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 EAU92329.1 - 5e-08 32.9 0.0 0.0053 16.4 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 EAU92329.1 - 0.021 14.8 0.5 0.051 13.5 0.1 1.8 2 0 0 2 2 2 0 PUB domain F-box-like PF12937.7 EAU92332.1 - 0.00051 19.9 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92332.1 - 0.005 16.7 1.6 0.14 12.1 1.6 2.8 1 1 0 1 1 1 1 F-box domain HSP70 PF00012.20 EAU92333.2 - 0.057 11.6 0.0 0.085 11.0 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein DDR PF08841.10 EAU92333.2 - 0.099 11.6 1.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Peptidase_M22 PF00814.25 EAU92333.2 - 0.17 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family efThoc1 PF11957.8 EAU92334.2 - 2e-92 310.4 3.4 2.4e-89 300.3 2.4 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Epimerase PF01370.21 EAU92334.2 - 3.1e-33 115.2 0.0 6e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EAU92334.2 - 4.7e-33 115.0 0.0 8.1e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EAU92334.2 - 0.0003 20.7 0.0 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EAU92334.2 - 0.0039 16.4 0.0 0.0074 15.4 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein PurS PF02700.14 EAU92334.2 - 0.15 12.2 0.1 0.62 10.3 0.1 2.0 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Dus PF01207.17 EAU92337.1 - 3.7e-53 180.6 0.0 8.2e-53 179.5 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TPR_1 PF00515.28 EAU92339.1 - 9.8e-13 47.3 17.1 0.00042 20.0 0.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU92339.1 - 6.5e-11 41.5 22.0 0.00042 20.2 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EAU92339.1 - 1e-09 37.9 18.3 6e-07 29.0 2.4 4.9 4 1 1 5 5 5 2 TPR repeat TPR_17 PF13431.6 EAU92339.1 - 2.2e-07 30.8 8.2 0.00026 21.1 0.6 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 EAU92339.1 - 0.045 13.8 10.6 13 6.0 0.1 5.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EAU92339.1 - 0.063 13.9 0.8 0.063 13.9 0.8 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EAU92339.1 - 0.28 11.3 7.7 1.5 9.0 0.5 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU92339.1 - 1.9 9.6 13.4 0.63 11.0 3.6 4.6 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EAU92339.1 - 2.1 8.9 12.9 0.32 11.5 1.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NSF PF02071.20 EAU92339.1 - 4.2 8.6 5.7 3.9 8.7 0.5 3.7 3 0 0 3 3 3 0 Aromatic-di-Alanine (AdAR) repeat TPR_2 PF07719.17 EAU92340.1 - 1.3e-12 46.8 3.1 0.00033 20.5 0.1 4.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EAU92340.1 - 4.4e-12 45.3 3.2 2.9e-05 23.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU92340.1 - 2.5e-08 33.5 0.2 8.3e-05 22.2 0.0 3.5 1 1 2 3 3 3 1 TPR repeat TPR_16 PF13432.6 EAU92340.1 - 5.8e-06 26.9 0.1 0.044 14.4 0.1 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU92340.1 - 8.8e-05 23.0 5.8 0.042 14.7 0.1 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAU92340.1 - 0.0024 18.4 0.1 0.025 15.1 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU92340.1 - 0.007 16.6 4.2 0.77 10.1 0.7 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EAU92340.1 - 0.014 15.7 0.3 1.3 9.6 0.1 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EAU92340.1 - 0.04 14.1 0.1 38 4.8 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 EAU92340.1 - 0.045 12.7 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) NETI PF14044.6 EAU92340.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 NETI protein TPR_1 PF00515.28 EAU92341.2 - 8.5e-21 72.9 9.1 3.8e-07 29.7 0.7 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU92341.2 - 5.9e-17 60.4 13.6 3.8e-06 26.6 0.2 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EAU92341.2 - 8.1e-10 39.2 7.7 2e-08 34.7 0.7 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU92341.2 - 1.2e-07 31.9 0.4 0.043 14.7 0.4 3.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU92341.2 - 1.5e-07 31.0 8.6 0.00096 18.8 4.6 3.3 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 EAU92341.2 - 1.8e-07 30.8 5.5 0.00088 19.3 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EAU92341.2 - 1.5e-06 28.3 5.5 0.048 13.9 0.1 5.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EAU92341.2 - 0.00028 20.7 2.2 0.81 9.6 0.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAU92341.2 - 0.00033 21.1 1.8 0.024 15.2 1.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAU92341.2 - 0.0008 19.6 6.9 0.12 12.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EAU92341.2 - 0.0077 16.2 5.2 0.26 11.4 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EAU92341.2 - 0.038 14.6 1.5 0.24 12.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU92341.2 - 0.071 13.3 1.1 0.2 11.9 1.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EAU92341.2 - 0.073 13.5 0.6 5.3 7.5 0.3 2.7 1 1 0 2 2 2 0 Bacterial transcriptional activator domain Prefoldin_2 PF01920.20 EAU92342.1 - 3.4e-17 62.3 6.7 4.1e-17 62.1 6.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.7 EAU92342.1 - 0.0087 16.2 2.3 0.0087 16.2 2.3 2.0 2 1 0 2 2 2 1 Tropomyosin like Mei5 PF10376.9 EAU92342.1 - 0.015 15.2 4.4 0.02 14.7 4.4 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein Phlebovirus_NSM PF07246.11 EAU92342.1 - 0.037 13.4 2.3 0.14 11.5 0.2 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Jnk-SapK_ap_N PF09744.9 EAU92342.1 - 0.097 12.9 5.2 0.17 12.1 0.9 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF148 PF02520.17 EAU92342.1 - 0.13 12.3 0.4 0.13 12.3 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF148 Seryl_tRNA_N PF02403.22 EAU92342.1 - 0.14 12.4 7.4 0.51 10.6 7.4 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cortex-I_coil PF09304.10 EAU92342.1 - 0.34 11.2 6.0 0.33 11.2 1.0 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil ABC2_membrane PF01061.24 EAU92343.2 - 6.2e-72 241.4 47.1 1.1e-37 129.5 19.7 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EAU92343.2 - 2.7e-33 115.4 0.0 4.2e-15 56.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EAU92343.2 - 6.4e-20 70.8 1.9 5e-16 58.4 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EAU92343.2 - 1.1e-12 48.4 0.9 3.1e-12 46.9 0.9 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 EAU92343.2 - 7.6e-06 26.5 0.0 0.029 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EAU92343.2 - 3.4e-05 24.0 0.2 0.037 14.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EAU92343.2 - 0.00032 21.0 0.1 0.69 10.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 EAU92343.2 - 0.00048 20.6 1.6 0.4 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EAU92343.2 - 0.001 19.5 1.1 0.058 13.8 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EAU92343.2 - 0.0013 18.4 0.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EAU92343.2 - 0.0065 16.3 0.1 1.1 9.1 0.0 2.6 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EAU92343.2 - 0.0078 15.8 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EAU92343.2 - 0.018 14.6 0.3 0.2 11.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAU92343.2 - 0.018 14.8 0.1 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EAU92343.2 - 0.018 15.5 0.1 3.4 8.1 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EAU92343.2 - 0.021 14.7 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SMC_N PF02463.19 EAU92343.2 - 0.028 13.9 0.1 0.57 9.6 0.0 2.8 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EAU92343.2 - 0.04 14.2 4.3 0.6 10.3 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EAU92343.2 - 0.042 14.2 0.6 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EAU92343.2 - 0.22 12.0 1.0 6.8 7.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain CAML PF14963.6 EAU92343.2 - 0.68 10.0 3.3 0.49 10.5 0.2 2.2 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand FtsK_SpoIIIE PF01580.18 EAU92343.2 - 1.2 8.5 3.1 26 4.0 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Glyco_hydro_cc PF11790.8 EAU92344.1 - 6.5e-66 222.3 0.2 8.1e-66 222.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF-hand_6 PF13405.6 EAU92345.1 - 3e-10 39.2 0.3 1.9e-05 24.2 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EAU92345.1 - 1.1e-07 31.0 1.1 0.00035 19.9 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EAU92345.1 - 3.7e-06 27.3 0.6 1.5e-05 25.4 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EAU92345.1 - 8.8e-05 21.8 0.2 0.1 12.2 0.0 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EAU92345.1 - 0.0013 19.1 0.5 0.86 9.9 0.2 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF4663 PF15668.5 EAU92345.1 - 0.25 10.4 1.5 0.38 9.8 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Dopey_N PF04118.14 EAU92346.2 - 2.2e-110 368.6 0.1 2.2e-110 368.6 0.1 2.6 3 0 0 3 3 3 1 Dopey, N-terminal DUF1338 PF07063.13 EAU92346.2 - 0.072 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) ATP-synt_E PF05680.12 EAU92348.2 - 3.4e-21 75.4 0.8 3.9e-21 75.2 0.8 1.1 1 0 0 1 1 1 1 ATP synthase E chain CAF1C_H4-bd PF12265.8 EAU92349.2 - 1.1e-25 89.7 0.6 2.5e-25 88.5 0.3 1.8 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EAU92349.2 - 3.4e-21 75.2 9.6 1.2e-05 25.9 0.2 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU92349.2 - 0.002 18.4 0.0 0.055 13.8 0.0 3.0 2 2 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain UPF0051 PF01458.17 EAU92349.2 - 0.11 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) RAMP4 PF06624.12 EAU92350.2 - 3.7e-20 71.7 0.1 4.1e-20 71.6 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3040 PF11239.8 EAU92350.2 - 0.037 14.3 0.0 0.038 14.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2431 PF10354.9 EAU92351.1 - 2e-53 181.1 0.0 2.8e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Fip1 PF05182.13 EAU92353.1 - 3.1e-20 71.4 1.4 5.7e-20 70.6 1.4 1.5 1 0 0 1 1 1 1 Fip1 motif Astro_capsid_p PF12226.8 EAU92353.1 - 1.5 7.9 8.1 2.3 7.3 8.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ING PF12998.7 EAU92354.1 - 1.8e-14 54.1 0.3 2.8e-14 53.5 0.3 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EAU92354.1 - 1e-05 25.3 5.0 1.7e-05 24.6 5.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EAU92354.1 - 0.15 11.7 2.3 0.25 10.9 2.3 1.4 1 0 0 1 1 1 0 PHD-finger Serglycin PF04360.12 EAU92354.1 - 6.3 6.7 8.6 1.1 9.2 3.2 2.1 1 1 1 2 2 2 0 Serglycin NAD_binding_1 PF00175.21 EAU92357.2 - 1.8e-28 99.3 0.0 3.1e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EAU92357.2 - 5.4e-18 65.2 0.0 9.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EAU92357.2 - 9.8e-08 32.3 0.1 5.9e-05 23.2 0.0 2.5 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EAU92357.2 - 0.044 14.0 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Pkinase PF00069.25 EAU92358.2 - 6.6e-66 222.4 0.0 8.1e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92358.2 - 1.3e-31 109.9 0.0 1.6e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EAU92358.2 - 8.6e-06 24.9 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EAU92358.2 - 0.00063 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAU92358.2 - 0.0007 19.0 0.1 0.0018 17.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAU92358.2 - 0.0033 16.8 0.0 0.052 12.8 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EAU92358.2 - 0.0081 15.8 0.1 0.044 13.4 0.0 2.0 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 EAU92358.2 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DNA_methylase PF00145.17 EAU92360.2 - 8.1e-36 124.0 0.0 2.9e-34 118.9 0.0 2.9 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EAU92360.2 - 1.5e-11 44.2 0.1 4.4e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 EAU92360.2 - 2e-09 37.6 0.0 5.2e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain DnaJ PF00226.31 EAU92361.1 - 1.6e-16 60.2 0.6 2.3e-16 59.6 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 EAU92361.1 - 1.4e-11 43.9 0.3 2.8e-11 43.0 0.3 1.4 1 0 0 1 1 1 1 CSL zinc finger Dor1 PF04124.12 EAU92363.1 - 6.9e-47 159.8 1.0 5e-32 110.9 0.6 2.2 2 0 0 2 2 2 2 Dor1-like family Sec5 PF15469.6 EAU92363.1 - 0.00061 19.7 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EAU92363.1 - 0.007 16.4 0.1 0.022 14.8 0.1 1.8 1 0 0 1 1 1 1 Vps51/Vps67 F-box-like PF12937.7 EAU92365.1 - 7.3e-06 25.8 0.3 1.6e-05 24.7 0.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU92365.1 - 0.18 12.3 0.2 37 4.9 0.0 3.7 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) NAM-associated PF14303.6 EAU92366.1 - 0.00026 21.8 0.0 0.00026 21.8 0.0 4.9 1 1 4 5 5 5 1 No apical meristem-associated C-terminal domain F-box-like PF12937.7 EAU92367.2 - 1.9e-06 27.7 0.1 4.8e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92367.2 - 2e-06 27.5 0.1 6.6e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EAU92367.2 - 0.29 11.0 1.7 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 F-box MRC1 PF09444.10 EAU92367.2 - 2.7 8.5 9.3 0.51 10.8 3.2 2.6 2 0 0 2 2 2 0 MRC1-like domain IBN_N PF03810.19 EAU92368.2 - 0.0001 22.1 0.0 0.18 11.7 0.0 4.2 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EAU92368.2 - 0.0016 18.8 0.3 0.062 13.7 0.0 3.9 5 0 0 5 5 5 1 HEAT repeats ParcG PF10274.9 EAU92368.2 - 0.0062 16.7 0.3 2.1 8.4 0.0 3.3 4 0 0 4 4 4 1 Parkin co-regulated protein DUF3385 PF11865.8 EAU92368.2 - 0.012 15.5 1.5 1.4 8.8 0.0 3.8 4 1 0 5 5 5 0 Domain of unknown function (DUF3385) CAS_CSE1 PF03378.15 EAU92368.2 - 0.02 13.4 0.7 0.096 11.2 0.0 2.5 4 0 0 4 4 4 0 CAS/CSE protein, C-terminus API5 PF05918.11 EAU92368.2 - 0.021 13.7 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) HEAT PF02985.22 EAU92368.2 - 0.026 14.7 3.5 0.33 11.3 0.1 4.5 5 0 0 5 5 5 0 HEAT repeat Xpo1 PF08389.12 EAU92368.2 - 0.031 14.4 0.0 0.22 11.6 0.0 2.7 2 1 0 2 2 2 0 Exportin 1-like protein Adaptin_N PF01602.20 EAU92368.2 - 0.11 11.0 0.0 0.63 8.5 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region TetR_C_32 PF09209.11 EAU92368.2 - 0.12 12.3 0.0 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UNC45-central PF11701.8 EAU92368.2 - 0.21 11.6 1.4 0.83 9.6 0.0 2.6 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central RabGAP-TBC PF00566.18 EAU92369.2 - 5.2e-44 150.5 0.0 8.8e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 EAU92371.1 - 9.4e-06 25.4 0.3 2.3e-05 24.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 EAU92371.1 - 0.043 13.4 0.5 0.12 12.0 0.5 1.7 1 0 0 1 1 1 0 F-box Tyrosinase PF00264.20 EAU92372.2 - 3e-41 142.1 0.7 4.1e-41 141.7 0.7 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Ank_4 PF13637.6 EAU92374.1 - 2.2e-12 47.2 0.0 3.8e-06 27.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EAU92374.1 - 9.7e-12 44.9 2.6 8.7e-06 25.9 0.3 3.5 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU92374.1 - 1.6e-11 43.3 0.2 0.00028 21.1 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EAU92374.1 - 4.9e-10 39.4 0.4 0.00072 19.9 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EAU92374.1 - 5.6e-10 39.7 0.0 9.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Pkinase PF00069.25 EAU92375.1 - 7.7e-35 120.5 0.0 2.3e-32 112.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92375.1 - 1.4e-17 63.9 0.0 2.1e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU92375.1 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EAU92375.1 - 0.00038 20.4 0.0 0.0065 16.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EAU92375.1 - 0.0043 16.2 0.0 0.0062 15.6 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.20 EAU92375.1 - 0.019 14.6 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EAU92375.1 - 0.022 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EAU92375.1 - 0.026 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Ask1 PF08655.10 EAU92376.1 - 1.2e-24 85.9 0.3 2.2e-24 85.1 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 CENP-B_dimeris PF09026.10 EAU92377.1 - 0.01 16.2 4.3 0.01 16.2 4.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Voldacs PF03517.13 EAU92377.1 - 0.047 13.8 3.9 0.074 13.2 0.5 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling BTK PF00779.19 EAU92377.1 - 0.86 9.5 5.5 0.27 11.1 1.6 2.0 2 0 0 2 2 2 0 BTK motif CHORD PF04968.12 EAU92377.1 - 5.7 7.7 9.9 0.48 11.2 0.6 2.6 2 1 0 2 2 2 0 CHORD Cu_amine_oxid PF01179.20 EAU92378.2 - 1.2e-152 508.6 0.0 1.5e-152 508.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EAU92378.2 - 7e-17 61.7 0.0 1.3e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EAU92378.2 - 0.00014 22.0 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TauD PF02668.16 EAU92379.2 - 1.9e-26 93.4 0.0 2.8e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C2H2_4 PF13894.6 EAU92380.2 - 7.5e-15 54.4 34.6 0.0029 18.3 0.1 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU92380.2 - 5.5e-12 45.4 39.1 0.00093 19.5 0.1 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAU92380.2 - 1.9e-09 37.6 25.7 0.011 16.0 0.1 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU92380.2 - 4e-05 23.9 30.8 0.0052 17.1 0.1 7.0 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAU92380.2 - 0.014 15.7 23.5 0.043 14.1 11.6 4.0 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 EAU92380.2 - 0.02 14.6 1.1 0.02 14.6 1.1 5.9 7 0 0 7 7 7 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EAU92380.2 - 0.053 13.4 0.0 0.053 13.4 0.0 5.9 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 EAU92380.2 - 0.17 11.5 24.7 0.42 10.2 0.0 5.6 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 EAU92380.2 - 0.28 11.7 0.4 0.28 11.7 0.4 6.6 6 1 0 6 6 5 0 Zinc-finger double domain DUF4187 PF13821.6 EAU92380.2 - 0.4 10.5 14.2 4.7 7.1 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4187) zf-C2H2_3rep PF18868.1 EAU92380.2 - 2.8 8.6 15.2 9.5 6.9 1.0 4.3 3 1 1 4 4 4 0 Zinc finger C2H2-type, 3 repeats DZR PF12773.7 EAU92380.2 - 3 8.0 26.4 3.5e+02 1.3 1.2 4.4 1 1 1 2 2 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 EAU92380.2 - 3.3 7.8 0.0 3.3 7.8 0.0 4.5 4 1 0 4 4 4 0 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.6 EAU92380.2 - 3.4 7.8 35.2 1.3 9.1 0.1 6.4 6 1 1 7 7 6 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 EAU92380.2 - 7.5 6.5 12.0 7.8 6.4 0.0 3.9 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-CCHC PF00098.23 EAU92381.1 - 7.3e-06 25.8 1.7 2.1e-05 24.4 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 EAU92381.1 - 0.014 15.1 0.5 0.024 14.3 0.5 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Retrotran_gag_2 PF14223.6 EAU92381.1 - 0.055 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1540 PF07561.11 EAU92383.1 - 0.24 11.7 1.0 0.56 10.5 1.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1540) DHR10 PF18595.1 EAU92383.1 - 0.66 10.0 6.6 0.06 13.4 1.1 2.0 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Alpha-amylase PF00128.24 EAU92384.2 - 0.18 11.3 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DUF4047 PF13256.6 EAU92384.2 - 0.18 12.0 0.0 0.29 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF2603 PF10788.9 EAU92385.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) DUF2760 PF10816.8 EAU92386.2 - 0.015 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) CxC4 PF18717.1 EAU92388.2 - 4.9e-47 159.1 0.4 1.1e-46 157.9 0.4 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EAU92388.2 - 0.088 12.4 0.5 0.17 11.5 0.5 1.3 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase zf-TFIIB PF13453.6 EAU92388.2 - 0.43 10.0 2.1 0.42 10.0 0.5 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger PTA_PTB PF01515.19 EAU92389.2 - 0.033 13.5 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase zf-C2H2_2 PF12756.7 EAU92389.2 - 0.038 14.3 6.2 1.1 9.6 0.3 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) G10 PF01125.17 EAU92389.2 - 0.038 13.7 0.3 0.052 13.3 0.3 1.4 1 1 0 1 1 1 0 G10 protein zf-C2H2_4 PF13894.6 EAU92389.2 - 0.5 11.4 6.5 5.8 8.0 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EAU92390.1 - 3.7e-14 52.2 36.7 0.013 16.2 1.0 8.2 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU92390.1 - 3.6e-12 46.0 41.5 0.068 13.7 1.3 7.9 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EAU92390.1 - 3.9e-12 46.1 27.1 9.8e-07 28.9 0.3 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU92390.1 - 1.1e-11 44.7 24.2 5.8e-06 26.5 0.3 6.1 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EAU92390.1 - 0.0016 18.4 1.8 0.0016 18.4 1.8 5.6 7 1 0 7 7 7 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EAU92390.1 - 0.011 16.0 25.9 0.2 12.0 1.7 4.7 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 EAU92390.1 - 0.32 11.5 0.0 0.32 11.5 0.0 6.9 7 0 0 7 7 7 0 Zinc-finger double domain zinc_ribbon_15 PF17032.5 EAU92390.1 - 2.5 8.9 18.2 0.1 13.3 1.3 3.6 2 1 1 3 3 3 0 zinc-ribbon family THEG4 PF15834.5 EAU92391.1 - 0.12 12.3 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Testis highly expressed protein 4 VASt PF16016.5 EAU92392.2 - 1e-38 133.1 0.1 2.2e-38 132.1 0.1 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EAU92392.2 - 1.6e-21 76.3 0.0 3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Homeodomain PF00046.29 EAU92393.1 - 1.8e-16 59.7 5.6 3.6e-16 58.7 5.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EAU92393.1 - 0.00093 19.1 0.1 0.0092 15.9 0.0 2.5 2 0 0 2 2 2 1 Homeobox KN domain MFS_1 PF07690.16 EAU92394.2 - 4.9e-24 84.9 25.4 4.9e-24 84.9 25.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Spec3 PF15795.5 EAU92394.2 - 2.1 9.0 9.5 13 6.4 0.1 4.3 4 1 0 4 4 4 0 Ectodermal ciliogenesis protein Enolase_C PF00113.22 EAU92397.1 - 7.6e-144 478.4 0.0 1e-143 478.0 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EAU92397.1 - 1.7e-59 199.7 0.1 2.7e-59 199.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EAU92397.1 - 3.9e-08 33.1 0.0 8.4e-08 32.0 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EAU92397.1 - 0.00086 18.5 0.1 0.002 17.3 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus NGP1NT PF08153.12 EAU92398.1 - 3.2e-51 172.9 0.0 9.2e-51 171.4 0.0 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EAU92398.1 - 5.3e-19 68.4 0.1 1.5e-14 54.0 0.0 2.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU92398.1 - 1.1e-05 25.1 0.1 7.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAU92398.1 - 2.5e-05 24.3 0.0 6.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 EAU92398.1 - 0.00032 20.3 0.3 0.024 14.2 0.1 2.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Nop14 PF04147.12 EAU92398.1 - 0.00043 18.7 24.0 0.00067 18.0 24.0 1.2 1 0 0 1 1 1 1 Nop14-like family Arf PF00025.21 EAU92398.1 - 0.02 14.3 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 EAU92398.1 - 0.023 14.9 0.1 4.4 7.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Nuc_deoxyrib_tr PF05014.15 EAU92398.1 - 0.042 13.9 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Mpp10 PF04006.12 EAU92398.1 - 0.062 11.8 32.1 0.089 11.2 32.1 1.1 1 0 0 1 1 1 0 Mpp10 protein NOG1 PF06858.14 EAU92398.1 - 0.16 11.8 0.2 0.33 10.8 0.2 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) PCM1_C PF15717.5 EAU92398.1 - 5.1 5.7 26.3 9.5 4.8 26.3 1.3 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus CDC45 PF02724.14 EAU92398.1 - 7.1 4.8 21.4 9.7 4.3 21.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4520 PF15016.6 EAU92400.2 - 0.091 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) PI-TkoII_IV PF18714.1 EAU92400.2 - 0.13 11.7 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV Inositol_P PF00459.25 EAU92401.1 - 9e-65 218.9 0.0 1.1e-64 218.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase PF00316.20 EAU92401.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Proteasome PF00227.26 EAU92402.1 - 1.1e-57 194.6 0.1 1.4e-57 194.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EAU92402.1 - 6.6e-14 51.3 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribonuc_L-PSP PF01042.21 EAU92403.1 - 9.5e-44 148.3 0.1 1.1e-43 148.1 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP G-alpha PF00503.20 EAU92404.2 - 2.5e-94 316.4 0.0 1.1e-93 314.2 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU92404.2 - 1.3e-12 47.5 0.1 2.4e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EAU92404.2 - 0.0051 17.0 0.0 0.95 9.7 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EAU92404.2 - 0.0065 16.2 0.0 0.025 14.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EAU92404.2 - 0.05 13.1 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAU92404.2 - 0.082 12.2 0.4 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region TniB PF05621.11 EAU92404.2 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Herpes_gE PF02480.16 EAU92405.2 - 0.028 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.20 EAU92405.2 - 0.14 12.1 0.6 0.44 10.5 0.6 1.8 1 0 0 1 1 1 0 Syndecan domain Glyco_hydro_47 PF01532.20 EAU92406.2 - 1.9e-145 485.3 0.0 2.4e-145 485.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PGF-CTERM PF18204.1 EAU92406.2 - 5.5 7.1 6.5 14 5.8 6.5 1.7 1 0 0 1 1 1 0 PGF-CTERM motif Trypan_PARP PF05887.11 EAU92408.1 - 0.015 15.2 4.3 0.015 15.2 4.3 2.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Tyrosinase PF00264.20 EAU92409.1 - 6.7e-42 144.3 3.2 9.6e-42 143.8 3.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase BTB_2 PF02214.22 EAU92410.1 - 0.0015 18.8 0.0 0.056 13.8 0.0 2.9 3 0 0 3 3 3 1 BTB/POZ domain PTE PF02126.18 EAU92410.1 - 0.17 11.3 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotriesterase family Cation_efflux PF01545.21 EAU92411.2 - 0.03 14.1 5.0 0.2 11.4 2.6 2.1 2 0 0 2 2 2 0 Cation efflux family RNF220 PF15926.5 EAU92411.2 - 1.1 8.8 11.5 4.6 6.8 11.5 1.8 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Chitin_synth_2 PF03142.15 EAU92412.2 - 3.8e-277 920.1 0.1 5.7e-277 919.5 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EAU92412.2 - 3.6e-10 40.1 0.6 1.5e-09 38.1 0.6 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EAU92412.2 - 1.9e-08 34.5 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EAU92412.2 - 0.00039 19.9 0.1 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EAU92412.2 - 0.09 12.6 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Cyt-b5 PF00173.28 EAU92412.2 - 0.16 12.1 0.0 8.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain ABC_tran PF00005.27 EAU92413.1 - 1.6e-27 96.7 0.0 4.4e-27 95.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU92413.1 - 2.6e-11 43.9 1.9 0.00022 21.2 0.2 3.1 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU92413.1 - 2.7e-06 27.0 0.0 0.0066 15.9 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EAU92413.1 - 5.7e-05 23.0 0.0 0.0093 15.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EAU92413.1 - 0.00079 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EAU92413.1 - 0.014 15.8 0.1 0.065 13.6 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 EAU92413.1 - 0.016 15.7 0.0 0.044 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EAU92413.1 - 0.019 15.2 0.0 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EAU92413.1 - 0.041 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EAU92413.1 - 0.08 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAU92413.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EAU92413.1 - 0.098 12.6 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Synapsin_N PF10581.9 EAU92413.1 - 0.12 12.3 0.0 0.41 10.6 0.0 1.9 1 0 0 1 1 1 0 Synapsin N-terminal RsgA_GTPase PF03193.16 EAU92413.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase zf-C2H2_4 PF13894.6 EAU92414.2 - 3.3e-06 27.5 4.1 0.0051 17.5 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU92414.2 - 4.2e-05 23.7 3.3 0.015 15.6 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EAU92414.2 - 4.6e-05 23.7 12.5 0.0056 17.1 1.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 EAU92414.2 - 0.064 13.6 0.3 0.13 12.5 0.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EAU92414.2 - 0.066 13.6 0.5 8.2 7.0 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RRN7 PF11781.8 EAU92414.2 - 0.17 11.6 1.1 17 5.2 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 PfkB PF00294.24 EAU92415.1 - 2e-69 234.2 1.7 2.2e-69 234.1 1.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EAU92415.1 - 0.00067 19.1 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase COesterase PF00135.28 EAU92417.2 - 6.4e-85 286.0 0.0 1.5e-83 281.5 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EAU92417.2 - 0.0011 18.8 0.4 0.1 12.5 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ribosomal_L28e PF01778.17 EAU92418.1 - 4.1e-31 108.1 0.0 5e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Med3 PF11593.8 EAU92418.1 - 0.34 10.1 3.6 0.39 9.9 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pox_Ag35 PF03286.14 EAU92419.1 - 0.15 11.8 6.9 0.18 11.6 6.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DAP PF15228.6 EAU92419.1 - 1.8 9.8 8.9 7.9 7.7 8.9 1.9 1 1 0 1 1 1 0 Death-associated protein F-box-like PF12937.7 EAU92421.2 - 4.4e-06 26.5 0.4 1.1e-05 25.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92421.2 - 0.00021 21.1 0.1 0.0014 18.4 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EAU92421.2 - 0.084 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 F-box LysM PF01476.20 EAU92422.1 - 6e-09 35.8 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 LysM domain Tyrosinase PF00264.20 EAU92423.1 - 1.3e-42 146.6 4.5 1.6e-42 146.3 4.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyridox_oxase_2 PF12766.7 EAU92424.1 - 1.4e-24 86.5 0.0 2.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EAU92424.1 - 0.0061 16.7 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Abhydrolase_1 PF00561.20 EAU92425.2 - 4.7e-17 62.5 0.1 1.6e-16 60.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU92425.2 - 1.2e-09 39.2 0.0 6.3e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU92425.2 - 9.9e-05 21.7 0.1 0.02 14.2 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAU92426.2 - 3.3e-19 69.5 0.0 2.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU92426.2 - 3.5e-15 57.2 0.0 5.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU92426.2 - 6e-11 42.1 0.0 1.9e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EAU92426.2 - 0.2 11.1 0.0 0.43 10.1 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) SecY PF00344.20 EAU92428.2 - 0.46 9.7 11.7 16 4.7 11.7 2.2 1 1 0 1 1 1 0 SecY translocase DUF3413 PF11893.8 EAU92429.2 - 0.037 13.2 13.9 0.24 10.5 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3413) YukC PF10140.9 EAU92429.2 - 0.11 11.4 0.3 0.24 10.2 0.3 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ERGIC_N PF13850.6 EAU92429.2 - 6.2 7.3 5.6 2.1 8.7 0.1 2.8 2 2 1 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TPR_9 PF13371.6 EAU92430.1 - 0.095 12.9 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RdRP PF05183.12 EAU92432.2 - 6.8e-86 289.2 0.0 2.1e-85 287.6 0.0 1.7 1 1 0 1 1 1 1 RNA dependent RNA polymerase LppC PF04348.13 EAU92432.2 - 0.0092 14.8 0.8 0.014 14.2 0.8 1.1 1 0 0 1 1 1 1 LppC putative lipoprotein EF-hand_7 PF13499.6 EAU92433.1 - 6.1e-27 93.9 13.7 2e-14 53.7 3.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EAU92433.1 - 7.7e-27 90.8 17.6 7e-10 37.7 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EAU92433.1 - 4e-23 79.3 12.5 7.5e-09 34.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EAU92433.1 - 8.5e-15 54.3 16.1 1.6e-10 40.7 1.3 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EAU92433.1 - 2.8e-13 48.7 7.2 0.00014 21.2 1.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EAU92433.1 - 2.2e-12 47.1 2.7 3.3e-05 24.1 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EAU92433.1 - 3.3e-08 33.4 7.2 0.00044 20.2 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EAU92433.1 - 5.3e-05 23.2 2.7 0.021 14.7 0.0 3.5 2 1 1 3 3 3 1 Caleosin related protein DUF150 PF02576.17 EAU92433.1 - 0.0053 17.1 1.1 0.52 10.7 0.1 2.4 1 1 1 2 2 2 1 RimP N-terminal domain SPARC_Ca_bdg PF10591.9 EAU92433.1 - 0.0075 16.6 4.1 0.29 11.4 0.8 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region CNP_C_terminal PF17839.1 EAU92433.1 - 0.028 15.1 0.5 0.37 11.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Dockerin_1 PF00404.18 EAU92433.1 - 0.032 14.4 0.4 0.51 10.6 0.7 2.2 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_14 PF17959.1 EAU92433.1 - 0.035 14.4 3.8 0.72 10.2 0.2 2.6 2 1 0 2 2 2 0 EF-hand domain EF-hand_11 PF08976.11 EAU92433.1 - 0.079 13.8 0.8 2.4 9.1 0.1 2.4 1 1 2 3 3 3 0 EF-hand domain Relaxase PF03432.14 EAU92433.1 - 0.14 11.7 2.9 0.16 11.6 1.6 1.7 1 1 1 2 2 2 0 Relaxase/Mobilisation nuclease domain SurA_N_2 PF13623.6 EAU92433.1 - 0.2 11.5 2.9 6.9 6.5 0.2 2.8 1 1 2 3 3 3 0 SurA N-terminal domain IF2_N PF04760.15 EAU92433.1 - 0.4 10.5 3.2 6.9 6.6 0.1 3.1 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Pkinase PF00069.25 EAU92435.1 - 6.9e-60 202.6 0.0 3e-58 197.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92435.1 - 2.3e-26 92.6 0.0 4e-15 55.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EAU92435.1 - 0.00042 21.0 6.6 0.0059 17.3 6.6 3.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 EAU92435.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAU92435.1 - 0.015 14.9 0.1 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 EAU92435.1 - 0.093 12.7 0.0 2.1 8.4 0.0 2.6 1 1 0 1 1 1 0 PX domain Kinase-like PF14531.6 EAU92435.1 - 0.16 11.3 0.1 3.9 6.7 0.0 2.4 3 0 0 3 3 3 0 Kinase-like Haspin_kinase PF12330.8 EAU92435.1 - 6.8 5.5 4.9 6.7 5.5 0.0 2.5 2 1 0 2 2 2 0 Haspin like kinase domain Alpha_kinase PF02816.18 EAU92438.2 - 3.4e-22 79.5 0.0 5.7e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family TauD PF02668.16 EAU92439.1 - 1.7e-47 162.4 0.0 2.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ribosomal_L21e PF01157.18 EAU92440.1 - 1.7e-45 153.0 3.5 4.1e-45 151.8 3.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Surface_Ag_2 PF01617.17 EAU92440.1 - 0.05 13.0 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 Surface antigen S4 PF01479.25 EAU92441.1 - 5.2e-11 42.1 1.5 5.2e-11 42.1 1.5 2.9 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EAU92441.1 - 3.1e-07 31.2 0.2 5.5e-07 30.4 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DNA_pol_B_thumb PF14791.6 EAU92442.1 - 2.4e-12 46.8 0.0 4.9e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 EAU92442.1 - 4.8e-11 42.9 0.3 1.3e-09 38.2 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 EAU92442.1 - 1.5e-09 38.1 0.0 3.8e-08 33.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 EAU92442.1 - 5.2e-08 32.6 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EAU92442.1 - 0.0082 16.7 0.7 0.02 15.5 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 EAU92442.1 - 0.034 14.0 0.1 0.25 11.3 0.1 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF4332 PF14229.6 EAU92442.1 - 0.081 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Raptor_N PF14538.6 EAU92443.2 - 1.5e-61 206.7 0.0 5.8e-61 204.7 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 EAU92443.2 - 5.5e-06 26.2 0.3 0.00059 19.9 0.1 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 EAU92443.2 - 3.1e-05 24.4 0.3 0.0025 18.3 0.1 3.5 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 EAU92443.2 - 0.0098 16.3 0.0 0.039 14.3 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats WD40 PF00400.32 EAU92443.2 - 0.013 16.3 20.2 0.097 13.6 0.6 5.8 6 0 0 6 6 6 0 WD domain, G-beta repeat Cohesin_HEAT PF12765.7 EAU92443.2 - 0.02 15.2 1.3 2.7 8.4 0.2 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EAU92443.2 - 0.096 12.7 0.0 0.76 9.8 0.0 2.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Peptidase_C14 PF00656.22 EAU92443.2 - 0.11 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Caspase domain BBS2_Mid PF14783.6 EAU92443.2 - 0.16 12.0 0.0 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Dynactin PF12455.8 EAU92444.2 - 1.5e-89 300.0 8.0 1.5e-89 300.0 8.0 3.3 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 EAU92444.2 - 3e-25 88.0 0.9 1.2e-24 86.1 1.0 1.9 2 0 0 2 2 2 1 CAP-Gly domain DUF3287 PF11690.8 EAU92444.2 - 0.59 9.9 7.1 2.5 7.8 0.5 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) CorA PF01544.18 EAU92445.2 - 2.2e-11 43.6 5.8 3.5e-06 26.5 0.2 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein GST_N PF02798.20 EAU92447.1 - 2.7e-13 50.0 0.1 4.4e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EAU92447.1 - 9.3e-11 41.8 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EAU92447.1 - 6.9e-08 32.7 0.1 2.6e-07 30.9 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU92447.1 - 2.9e-07 30.8 0.0 8.1e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAU92447.1 - 0.00036 20.7 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU92447.1 - 0.0015 18.5 0.0 0.0051 16.8 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 EAU92448.2 - 0.035 14.0 0.2 0.09 12.7 0.2 1.7 1 0 0 1 1 1 0 F-box-like UBA PF00627.31 EAU92449.2 - 0.00069 19.5 1.7 0.0035 17.2 0.0 3.1 3 1 1 4 4 4 1 UBA/TS-N domain TPR_2 PF07719.17 EAU92449.2 - 0.001 19.0 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EAU92449.2 - 0.07 13.0 0.0 3.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 EAU92449.2 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain SOSSC PF15925.5 EAU92449.2 - 9.8 7.6 7.4 3.6 8.9 0.1 3.4 3 0 0 3 3 3 0 SOSS complex subunit C CorA PF01544.18 EAU92450.2 - 1.1e-26 93.8 10.8 1.1e-17 64.3 0.4 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Polysacc_deac_1 PF01522.21 EAU92458.2 - 8.8e-05 22.4 0.1 0.00045 20.1 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase F-box-like PF12937.7 EAU92459.1 - 1.2e-07 31.5 0.7 2.6e-07 30.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU92459.1 - 3.1e-06 26.9 0.2 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EAU92459.1 - 0.034 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 F-box F-box-like_2 PF13013.6 EAU92459.1 - 0.053 13.5 0.6 0.52 10.3 0.1 2.5 2 1 1 3 3 3 0 F-box-like domain Vta1_C PF18097.1 EAU92459.1 - 0.16 11.7 0.8 10 5.9 0.1 2.6 2 0 0 2 2 2 0 Vta1 C-terminal domain zf-C2H2 PF00096.26 EAU92460.1 - 1.1e-07 31.9 14.0 0.00038 20.7 4.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU92460.1 - 0.00016 22.0 6.4 0.00016 22.0 6.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EAU92460.1 - 0.00049 20.7 13.5 0.035 14.9 2.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EAU92460.1 - 0.0061 17.2 5.7 0.1 13.2 0.2 2.5 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EAU92460.1 - 0.0099 16.2 1.2 0.021 15.1 1.2 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon Ogr_Delta PF04606.12 EAU92460.1 - 0.031 14.2 0.6 0.52 10.3 0.0 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger FANCL_C PF11793.8 EAU92460.1 - 0.15 12.3 1.0 0.26 11.5 1.0 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C2H2_jaz PF12171.8 EAU92460.1 - 6.1 7.2 8.6 0.3 11.4 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNA_ligase PF09414.10 EAU92461.1 - 1.9e-30 106.3 0.0 3.2e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 EAU92461.1 - 7.6e-14 52.1 0.2 2e-05 24.8 0.0 2.6 2 1 1 3 3 3 2 AAA domain Y_phosphatase PF00102.27 EAU92461.1 - 1.7e-06 27.8 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EAU92461.1 - 0.00015 21.9 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EAU92461.1 - 0.001 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EAU92461.1 - 0.0083 16.3 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EAU92461.1 - 0.031 14.1 0.1 0.091 12.6 0.1 1.8 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AAA_22 PF13401.6 EAU92461.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EAU92461.1 - 0.1 13.1 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain CDKN3 PF05706.12 EAU92461.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_8 PF13181.6 EAU92461.1 - 0.13 12.5 0.4 12 6.4 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_5 PF07728.14 EAU92461.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 6PF2K PF01591.18 EAU92461.1 - 0.2 11.0 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RCC1 PF00415.18 EAU92462.1 - 1.1e-34 118.8 20.9 4.5e-07 30.4 0.6 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EAU92462.1 - 4.7e-17 61.3 27.4 4.5e-06 26.3 0.3 7.9 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat ABC_tran PF00005.27 EAU92463.2 - 6.6e-52 175.7 0.0 1.8e-27 96.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EAU92463.2 - 1.6e-24 86.7 36.4 5.1e-13 48.9 17.2 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EAU92463.2 - 1.1e-17 64.8 7.5 3.1e-06 27.2 0.0 4.5 5 0 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAU92463.2 - 1e-07 32.6 1.8 0.0045 17.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 EAU92463.2 - 2e-07 31.6 0.0 0.02 15.6 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SMC_N PF02463.19 EAU92463.2 - 2.5e-06 27.1 0.0 0.038 13.4 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EAU92463.2 - 9.9e-05 22.0 0.2 0.31 10.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EAU92463.2 - 0.00075 19.3 0.2 0.2 11.3 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EAU92463.2 - 0.00079 19.4 0.2 0.97 9.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 EAU92463.2 - 0.0012 18.5 0.2 0.37 10.3 0.1 2.4 2 0 0 2 2 2 2 AAA domain MukB PF04310.12 EAU92463.2 - 0.0029 17.4 0.4 1.9 8.3 0.0 2.4 2 0 0 2 2 2 2 MukB N-terminal AAA_30 PF13604.6 EAU92463.2 - 0.0048 16.6 2.2 3.1 7.5 0.3 3.3 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 EAU92463.2 - 0.05 12.9 0.0 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 EAU92463.2 - 0.072 13.4 1.1 15 5.9 0.1 3.3 2 2 0 2 2 2 0 AAA domain SRP54 PF00448.22 EAU92463.2 - 0.2 11.2 2.9 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 EAU92463.2 - 0.62 9.5 46.6 0.077 12.4 14.2 4.2 4 1 0 4 4 4 0 ABC-2 type transporter CRAL_TRIO PF00650.20 EAU92465.1 - 2.1e-37 128.3 0.0 2.8e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EAU92465.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EAU92465.1 - 0.0071 16.5 0.0 0.0095 16.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cu-oxidase_3 PF07732.15 EAU92467.2 - 3.3e-33 114.2 0.0 4.2e-30 104.2 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EAU92467.2 - 3.5e-27 95.5 0.0 5.1e-26 91.7 0.0 2.6 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU92467.2 - 3.3e-22 78.7 0.2 8.7e-20 70.9 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase VPS28 PF03997.12 EAU92468.1 - 0.19 11.3 2.4 0.33 10.6 2.4 1.5 1 1 0 1 1 1 0 VPS28 protein Thioredoxin PF00085.20 EAU92470.1 - 8.3e-28 96.4 0.0 9.9e-28 96.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EAU92470.1 - 2.4e-09 37.6 0.3 1.7e-07 31.6 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAU92470.1 - 2.5e-06 27.7 0.1 0.0001 22.6 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EAU92470.1 - 2.5e-06 27.3 0.0 2.8e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EAU92470.1 - 1e-05 25.3 0.1 0.0013 18.4 0.0 2.1 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EAU92470.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EAU92470.1 - 0.0018 17.7 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF2847 PF11009.8 EAU92470.1 - 0.01 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Glutaredoxin PF00462.24 EAU92470.1 - 0.011 16.0 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_7 PF13899.6 EAU92470.1 - 0.022 14.9 0.2 0.032 14.4 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 EAU92470.1 - 0.034 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Flagellin_D3 PF08884.11 EAU92470.1 - 0.045 14.1 0.1 0.067 13.6 0.1 1.3 1 0 0 1 1 1 0 Flagellin D3 domain Thioredoxin_5 PF13743.6 EAU92470.1 - 0.064 12.9 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Cu-oxidase PF00394.22 EAU92471.1 - 1.7e-43 148.5 0.5 1.1e-42 145.8 0.1 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EAU92471.1 - 5e-41 139.5 0.2 7.1e-39 132.5 0.1 3.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EAU92471.1 - 1.8e-23 82.8 3.9 2.2e-20 72.8 0.1 4.2 3 2 0 3 3 3 2 Multicopper oxidase DUF4625 PF15418.6 EAU92471.1 - 0.019 15.2 0.0 0.049 13.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Methyltransf_16 PF10294.9 EAU92473.1 - 4.1e-20 72.2 0.0 6.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EAU92473.1 - 2.8e-06 27.2 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU92473.1 - 3.8e-06 27.5 0.0 8.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU92473.1 - 1.8e-05 25.4 0.0 4.9e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EAU92473.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EAU92473.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EAU92473.1 - 0.0027 17.5 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EAU92473.1 - 0.0048 17.5 0.0 0.0098 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU92473.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EAU92473.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ribosomal_L2_C PF03947.18 EAU92475.1 - 1.1e-53 180.7 0.8 2.3e-53 179.7 0.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EAU92475.1 - 2.2e-25 88.4 0.4 4.5e-25 87.4 0.4 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TIP49 PF06068.13 EAU92476.1 - 4.7e-157 522.7 0.5 6.8e-157 522.1 0.5 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EAU92476.1 - 3.8e-21 75.0 0.3 2.3e-20 72.5 0.4 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EAU92476.1 - 2.3e-09 37.8 0.2 4.3e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAU92476.1 - 2.7e-07 30.5 0.1 0.00042 20.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EAU92476.1 - 1e-05 25.1 0.5 1.9e-05 24.2 0.5 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EAU92476.1 - 1.3e-05 25.6 0.1 6.6e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EAU92476.1 - 0.0047 16.5 0.3 0.015 14.9 0.3 1.9 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EAU92476.1 - 0.0048 16.7 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EAU92476.1 - 0.0048 16.3 1.3 0.072 12.5 0.3 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EAU92476.1 - 0.0086 16.4 0.1 0.33 11.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EAU92476.1 - 0.039 14.0 1.9 10 6.1 0.0 3.6 4 1 1 5 5 5 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EAU92476.1 - 0.051 13.1 0.5 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Aldo_ket_red PF00248.21 EAU92477.1 - 4.8e-64 216.4 0.0 5.7e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_attach PF05354.11 EAU92477.1 - 0.2 11.6 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Phage Head-Tail Attachment PUF PF00806.19 EAU92478.1 - 4e-28 95.5 0.0 2e-07 30.3 0.0 6.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat TFIIA PF03153.13 EAU92479.1 - 0.2 11.6 17.6 0.86 9.5 11.6 2.7 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.9 EAU92479.1 - 7.7 6.1 19.3 0.016 14.8 6.2 2.7 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Aldo_ket_red PF00248.21 EAU92482.1 - 7.1e-70 235.5 0.0 8.3e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family D5_N PF08706.11 EAU92482.1 - 0.11 12.8 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 D5 N terminal like Fasciclin PF02469.22 EAU92483.1 - 4e-08 33.5 0.0 6.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain HTH_41 PF14502.6 EAU92483.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Metallophos PF00149.28 EAU92485.1 - 1.1e-11 45.6 0.2 1.5e-11 45.2 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EAU92485.1 - 8.7e-07 29.3 0.0 0.00013 22.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Adaptin_N PF01602.20 EAU92486.2 - 2.5e-89 300.2 7.8 2.5e-89 300.2 7.8 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EAU92486.2 - 1.7e-59 199.4 0.0 5.3e-59 197.8 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EAU92486.2 - 3.2e-54 182.6 0.0 8.4e-54 181.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 EAU92486.2 - 4e-11 43.2 6.3 0.00046 20.5 0.0 5.8 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.22 EAU92486.2 - 6e-10 38.5 2.6 0.087 13.1 0.0 6.4 5 1 1 6 6 6 3 HEAT repeat DUF5578 PF17741.1 EAU92486.2 - 6.5e-05 22.5 7.2 0.079 12.4 2.5 2.9 2 1 1 3 3 3 2 Family of unknown function (DUF5578) Coatomer_g_Cpla PF16381.5 EAU92486.2 - 7e-05 22.9 0.0 0.0016 18.6 0.0 3.0 3 0 0 3 3 3 1 Coatomer subunit gamma-1 C-terminal appendage platform Cnd1 PF12717.7 EAU92486.2 - 0.00017 21.7 16.3 0.0011 19.0 0.0 4.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EAU92486.2 - 0.0035 17.5 4.0 0.15 12.3 0.0 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 TrpBP PF02081.15 EAU92486.2 - 0.018 14.8 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein RasGEF_N_2 PF14663.6 EAU92486.2 - 0.018 15.4 8.4 1.2 9.5 0.0 5.3 4 2 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 EAU92486.2 - 0.022 14.9 4.2 0.68 10.0 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein DUF5071 PF16804.5 EAU92486.2 - 0.023 15.0 3.2 0.25 11.6 0.0 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF5071) HEAT_EZ PF13513.6 EAU92486.2 - 0.033 14.7 0.2 9.9 6.8 0.0 4.3 4 1 0 4 4 4 0 HEAT-like repeat Meis_PKNOX_N PF16493.5 EAU92486.2 - 2 8.8 4.9 0.51 10.7 0.2 2.5 3 0 0 3 3 1 0 N-terminal of Homeobox Meis and PKNOX1 RNA_pol_Rpb2_3 PF04565.16 EAU92487.2 - 0.15 12.2 0.8 0.9 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 Nramp PF01566.18 EAU92488.2 - 1.5e-85 287.3 18.8 3.4e-45 154.6 5.3 2.4 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein Adap_comp_sub PF00928.21 EAU92490.2 - 3.9e-20 72.3 0.0 6e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EAU92490.2 - 6.4e-09 35.9 0.1 1.1e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_2 PF12796.7 EAU92491.1 - 1.6e-40 137.6 0.0 1.4e-10 41.7 0.0 5.9 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU92491.1 - 8.6e-29 99.2 4.6 3e-06 27.4 0.0 7.3 6 2 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EAU92491.1 - 2e-28 95.3 4.2 0.0084 16.5 0.0 11.8 10 2 1 11 11 11 5 Ankyrin repeat Ank PF00023.30 EAU92491.1 - 1.1e-27 95.3 5.5 2.7e-05 24.4 0.0 10.4 10 1 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.6 EAU92491.1 - 8.4e-27 93.2 1.7 0.0002 21.9 0.0 9.7 4 3 6 10 10 10 8 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU92491.1 - 0.0003 21.1 0.0 0.00071 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EAU92491.1 - 0.0018 17.5 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EAU92491.1 - 0.0085 16.0 0.1 0.028 14.3 0.1 2.0 1 1 0 1 1 1 1 NACHT domain Annexin PF00191.20 EAU92492.1 - 6.6e-29 99.8 2.1 2.7e-09 36.9 0.0 3.5 3 0 0 3 3 3 3 Annexin YlbE PF14003.6 EAU92492.1 - 0.12 12.9 1.8 3.7 8.1 0.0 2.8 3 0 0 3 3 3 0 YlbE-like protein Annexin PF00191.20 EAU92494.2 - 4.3e-45 151.6 5.5 1e-16 60.8 0.2 4.7 4 1 0 4 4 4 4 Annexin Annexin PF00191.20 EAU92495.2 - 7.2e-25 86.8 0.1 4.2e-10 39.5 0.2 4.0 4 0 0 4 4 4 3 Annexin YlbE PF14003.6 EAU92495.2 - 0.057 13.9 0.0 2.6 8.6 0.0 2.7 2 0 0 2 2 2 0 YlbE-like protein Scs3p PF10261.9 EAU92496.2 - 0.23 10.9 0.5 0.7 9.4 0.4 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM OrfB_Zn_ribbon PF07282.11 EAU92496.2 - 0.3 11.0 2.0 0.68 9.9 2.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain GreA_GreB_N PF03449.15 EAU92499.1 - 0.093 12.9 0.2 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DprA_WH PF17782.1 EAU92499.1 - 0.2 11.8 0.3 0.2 11.8 0.3 2.0 2 0 0 2 2 2 0 DprA winged helix domain VWA_2 PF13519.6 EAU92499.1 - 0.3 11.7 2.0 5.3 7.8 0.1 1.9 1 1 1 2 2 2 0 von Willebrand factor type A domain Spore_III_AB PF09548.10 EAU92500.1 - 0.049 13.7 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Ank_2 PF12796.7 EAU92501.2 - 1.5e-40 137.6 2.7 9.8e-11 42.1 0.0 5.6 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EAU92501.2 - 1.4e-30 104.9 4.6 8.3e-08 32.4 0.1 6.3 6 0 0 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EAU92501.2 - 9.8e-28 95.4 7.8 0.0022 18.4 0.0 10.3 11 0 0 11 11 11 6 Ankyrin repeat Ank_3 PF13606.6 EAU92501.2 - 4.3e-27 91.2 2.0 0.076 13.6 0.0 11.6 11 1 0 11 11 11 7 Ankyrin repeat Ank_4 PF13637.6 EAU92501.2 - 5.3e-24 84.3 4.7 0.0061 17.1 0.0 9.5 4 2 5 9 9 9 6 Ankyrin repeats (many copies) AAA_22 PF13401.6 EAU92501.2 - 0.00015 22.1 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EAU92501.2 - 0.0018 17.5 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EAU92501.2 - 0.0084 16.0 0.0 0.034 14.1 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU92501.2 - 0.053 13.9 0.1 1.9 8.9 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain UPF0203 PF05254.12 EAU92502.1 - 7.5e-27 93.4 2.9 8.9e-27 93.1 2.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 EAU92502.1 - 0.0087 16.2 3.8 0.75 10.0 1.3 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 EAU92502.1 - 0.061 13.6 0.8 1.4 9.3 0.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 EAU92502.1 - 0.077 13.4 0.7 1.2 9.6 0.3 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Gal-bind_lectin PF00337.22 EAU92504.1 - 5.5e-05 22.7 0.0 6.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Galactoside-binding lectin Man-6-P_recep PF02157.15 EAU92505.2 - 4.5e-06 25.9 0.0 7.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Cwf_Cwc_15 PF04889.12 EAU92505.2 - 0.0002 21.2 1.6 0.00028 20.7 1.6 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein ATG27 PF09451.10 EAU92505.2 - 0.00074 19.5 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 SDA1 PF05285.12 EAU92505.2 - 0.024 14.1 1.0 0.031 13.7 1.0 1.1 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 EAU92505.2 - 0.54 10.0 4.0 1 9.1 4.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 EAU92505.2 - 2.4 7.8 5.4 5.2 6.7 5.4 1.5 1 0 0 1 1 1 0 FAM176 family Totivirus_coat PF05518.11 EAU92505.2 - 3.1 5.7 8.9 4 5.4 8.9 1.2 1 0 0 1 1 1 0 Totivirus coat protein RXT2_N PF08595.11 EAU92505.2 - 6.4 6.8 9.4 12 5.9 9.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Complex1_49kDa PF00346.19 EAU92506.2 - 1.4e-108 362.2 0.0 2.1e-108 361.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EAU92506.2 - 0.0038 16.2 0.0 0.0077 15.2 0.0 1.5 1 0 0 1 1 1 1 Nickel-dependent hydrogenase SLBP_RNA_bind PF15247.6 EAU92506.2 - 0.12 12.5 0.0 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain NIF3 PF01784.18 EAU92507.2 - 4.4e-53 180.4 0.0 5.8e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) TPX2 PF06886.11 EAU92509.1 - 1.5e-09 37.9 21.7 1.5e-09 37.9 21.7 2.5 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) AAA_23 PF13476.6 EAU92509.1 - 0.39 11.2 6.3 0.66 10.4 6.3 1.4 1 0 0 1 1 1 0 AAA domain ECH_1 PF00378.20 EAU92510.1 - 4.6e-57 193.2 0.0 6.3e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EAU92510.1 - 1.1e-28 100.7 0.0 1.5e-28 100.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF4115 PF13464.6 EAU92511.1 - 0.13 12.4 0.1 0.68 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) Glutaredoxin PF00462.24 EAU92516.1 - 1.6e-17 63.5 0.1 2.2e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EAU92516.1 - 0.00045 20.6 0.2 0.00082 19.8 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EAU92516.1 - 0.0073 16.7 0.1 0.0088 16.4 0.1 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 EAU92516.1 - 0.012 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 EAU92516.1 - 0.03 14.5 0.0 0.045 13.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like GST_N_3 PF13417.6 EAU92516.1 - 0.034 14.5 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PhoR PF11808.8 EAU92518.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Yae1_N PF09811.9 EAU92521.2 - 7.1e-11 41.6 6.1 1.1e-10 41.1 6.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF1115 PF06544.12 EAU92522.1 - 8.5e-07 29.2 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.18 EAU92522.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 2 0 0 2 2 2 0 Acylphosphatase Aminotran_1_2 PF00155.21 EAU92523.2 - 2.2e-41 142.3 0.0 3.3e-41 141.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EAU92523.2 - 0.0077 15.6 0.2 0.014 14.7 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EAU92523.2 - 0.035 12.6 0.0 0.06 11.9 0.0 1.3 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EAU92523.2 - 0.056 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V N_BRCA1_IG PF16158.5 EAU92526.1 - 2.9e-29 101.8 0.1 7.2e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EAU92526.1 - 6.4e-24 83.5 34.4 9.3e-09 35.0 4.4 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 EAU92526.1 - 6.4e-07 29.6 35.2 0.0058 16.9 6.4 3.4 3 0 0 3 3 3 3 C1 domain PB1 PF00564.24 EAU92526.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 PB1 domain WD40 PF00400.32 EAU92527.1 - 3.9e-58 192.1 18.2 8.2e-06 26.5 0.2 10.8 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 EAU92527.1 - 2.1e-49 167.1 0.0 3.7e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EAU92527.1 - 1.3e-12 47.9 1.8 0.32 11.3 0.1 7.5 6 2 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAU92527.1 - 6.3e-06 25.7 0.4 0.0015 18.0 0.0 3.2 3 0 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EAU92527.1 - 3.1e-05 23.1 2.8 0.077 11.9 0.1 4.7 3 2 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 EAU92527.1 - 0.02 14.0 0.0 3.1 6.7 0.0 3.1 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Forkhead PF00250.18 EAU92528.2 - 1.9e-19 69.7 0.0 3.2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain ATG16 PF08614.11 EAU92528.2 - 3.2e-05 24.3 1.6 7.1e-05 23.1 1.6 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Vac_Fusion PF02346.16 EAU92528.2 - 0.055 13.1 0.5 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Lebercilin PF15619.6 EAU92528.2 - 0.098 12.3 6.1 0.15 11.7 6.1 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4763 PF15960.5 EAU92528.2 - 0.14 11.4 1.5 0.28 10.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Fib_alpha PF08702.10 EAU92528.2 - 0.22 11.7 2.7 0.38 10.9 2.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 EAU92528.2 - 0.69 9.3 6.0 1 8.8 6.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Fungal_trans PF04082.18 EAU92529.2 - 6.1e-36 123.8 0.0 9.1e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NIPSNAP PF07978.13 EAU92530.1 - 1.6e-27 95.7 0.2 1.9e-27 95.5 0.2 1.1 1 0 0 1 1 1 1 NIPSNAP DUF953 PF06110.11 EAU92534.1 - 2.7e-18 65.7 0.0 3e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 EAU92534.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EAU92534.1 - 0.081 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 EAU92534.1 - 0.17 12.4 0.4 0.54 10.7 0.4 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Terminase_3C PF17288.2 EAU92535.1 - 2.7 8.4 8.3 5.9 7.3 0.2 2.6 1 1 1 2 2 2 0 Terminase RNAseH like domain Mito_carr PF00153.27 EAU92536.2 - 8.5e-67 221.1 0.9 4.5e-24 84.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EAU92536.2 - 2.4e-17 63.1 2.4 1.7e-05 25.1 0.1 4.7 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EAU92536.2 - 1.6e-15 55.4 5.7 6.9e-07 28.4 0.1 5.6 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EAU92536.2 - 1.4e-13 49.6 6.9 2.2e-05 24.0 0.1 5.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 EAU92536.2 - 2.5e-09 36.8 3.7 0.0016 18.3 0.0 4.9 4 1 2 6 6 6 2 EF-hand domain pair EF-hand_5 PF13202.6 EAU92536.2 - 4.6e-08 32.2 5.9 2e-05 23.9 0.0 3.7 3 0 0 3 3 3 2 EF hand Met_10 PF02475.16 EAU92537.2 - 7.9e-70 234.7 0.0 2.3e-69 233.2 0.0 1.7 2 0 0 2 2 2 1 Met-10+ like-protein MethyltransfD12 PF02086.15 EAU92537.2 - 0.00068 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 EAU92537.2 - 0.13 11.9 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TRM PF02005.16 EAU92537.2 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase TatD_DNase PF01026.21 EAU92538.1 - 3.5e-29 102.0 0.0 4.9e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Lgl_C PF08596.10 EAU92540.2 - 8.1e-34 117.0 0.0 1.3e-32 113.0 0.0 2.5 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EAU92540.2 - 5.5e-07 29.8 0.0 0.19 12.1 0.0 4.2 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU92540.2 - 0.0019 19.0 4.0 0.051 14.5 0.2 4.4 6 0 0 6 6 6 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EAU92540.2 - 0.0026 16.6 0.0 0.018 13.8 0.0 2.4 3 1 0 3 3 3 1 Nup133 N terminal like APG6_N PF17675.1 EAU92541.2 - 0.0011 19.5 10.4 0.0011 19.5 10.4 13.1 3 2 7 11 11 11 3 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 EAU92541.2 - 0.0027 17.8 1.1 0.0027 17.8 1.1 14.1 5 2 9 15 15 15 3 TPR/MLP1/MLP2-like protein CC2-LZ PF16516.5 EAU92541.2 - 0.0036 17.6 9.1 0.0036 17.6 9.1 16.2 6 4 10 17 17 17 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PKcGMP_CC PF16808.5 EAU92541.2 - 0.0079 16.0 6.0 0.0079 16.0 6.0 15.8 19 0 0 19 19 19 3 Coiled-coil N-terminus of cGMP-dependent protein kinase Exog_C PF18026.1 EAU92541.2 - 2.1 8.5 6.0 1.1 9.4 1.0 3.3 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain YqjK PF13997.6 EAU92541.2 - 7.6 6.9 6.3 71 3.8 0.2 4.6 3 0 0 3 3 3 0 YqjK-like protein DUF89 PF01937.19 EAU92542.1 - 1.4e-106 356.4 0.0 1.8e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 NDUFV3 PF15880.5 EAU92542.1 - 0.041 13.9 0.3 0.81 9.8 0.1 2.7 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial zf-RING_2 PF13639.6 EAU92543.2 - 1.1e-10 41.6 6.3 1.1e-10 41.6 6.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EAU92543.2 - 1.2e-09 38.3 7.8 1.3e-09 38.2 5.8 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EAU92543.2 - 8.6e-07 28.7 8.1 8.6e-07 28.7 8.1 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EAU92543.2 - 3e-06 27.0 6.3 3e-06 27.0 6.3 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU92543.2 - 1.5e-05 24.9 6.5 1.5e-05 24.9 6.5 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAU92543.2 - 2.8e-05 24.0 4.0 2.8e-05 24.0 4.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EAU92543.2 - 3.5e-05 23.8 0.4 3.5e-05 23.8 0.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 EAU92543.2 - 3.7e-05 23.9 1.7 3.7e-05 23.9 1.7 2.6 3 0 0 3 3 2 1 zinc-ribbon zf-RING_11 PF17123.5 EAU92543.2 - 7.3e-05 22.4 5.6 0.00023 20.9 5.6 1.9 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EAU92543.2 - 0.0023 17.7 10.1 0.0036 17.1 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU92543.2 - 0.022 14.6 5.3 0.058 13.3 5.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EAU92543.2 - 0.17 12.1 4.7 0.84 9.9 4.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain SPX PF03105.19 EAU92543.2 - 0.28 11.1 3.7 0.44 10.4 3.7 1.4 1 0 0 1 1 1 0 SPX domain HypA PF01155.19 EAU92543.2 - 0.78 9.8 3.8 9.2 6.3 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EAU92543.2 - 0.8 9.8 5.5 9.3 6.4 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 EAU92543.2 - 9.5 6.2 14.5 0.27 11.2 3.6 2.6 3 0 0 3 3 3 0 PHD-finger Gcd10p PF04189.13 EAU92549.2 - 5.3e-55 186.7 0.0 3.7e-52 177.3 0.0 2.1 1 1 1 2 2 2 2 Gcd10p family LPD34 PF18852.1 EAU92549.2 - 0.049 13.2 1.3 0.19 11.3 0.5 1.9 2 0 0 2 2 2 0 Large polyvalent protein associated domain 34 Fibin PF15819.5 EAU92549.2 - 0.12 12.2 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Fin bud initiation factor homologue PXA PF02194.15 EAU92550.2 - 2.1e-52 177.7 0.7 1e-51 175.5 0.2 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EAU92550.2 - 9.3e-30 103.5 0.1 3.8e-29 101.5 0.1 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EAU92550.2 - 1.9e-15 56.8 0.0 9e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.19 EAU92550.2 - 2.6e-11 43.8 0.2 1e-10 41.9 0.2 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Isy1 PF06246.12 EAU92550.2 - 0.1 12.1 0.0 0.1 12.1 0.0 2.2 2 1 0 2 2 2 0 Isy1-like splicing family Mito_carr PF00153.27 EAU92551.2 - 7.2e-55 182.9 0.9 4.3e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.18 EAU92552.1 - 4.8e-12 45.9 4.3 4.8e-12 45.9 4.3 1.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 EAU92553.1 - 2.6e-12 46.8 1.5 5.3e-12 45.7 0.0 2.1 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) UDPGP PF01704.18 EAU92554.1 - 1.6e-47 162.1 0.0 2.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EAU92554.1 - 0.0076 16.6 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Taxilin PF09728.9 EAU92555.1 - 7.2e-22 77.9 36.0 5.6e-13 48.7 4.6 2.8 2 1 1 3 3 3 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 EAU92555.1 - 8.4e-08 31.9 0.7 0.0055 16.5 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EAU92555.1 - 0.043 13.6 0.1 0.35 10.6 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin family PriA_C PF18074.1 EAU92555.1 - 0.086 13.7 0.2 0.086 13.7 0.2 3.0 2 2 1 3 3 3 0 Primosomal protein N C-terminal domain DUF3772 PF12607.8 EAU92555.1 - 0.54 10.1 4.3 0.6 9.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) DUF2935 PF11155.8 EAU92555.1 - 0.8 10.0 6.6 1.2 9.5 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Cupin_6 PF12852.7 EAU92555.1 - 1.6 8.4 4.4 0.47 10.1 0.1 2.2 3 0 0 3 3 3 0 Cupin KxDL PF10241.9 EAU92555.1 - 5.3 7.4 14.7 0.39 11.0 8.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF4407 PF14362.6 EAU92555.1 - 7.6 5.8 22.0 9.9 5.4 14.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2497 PF10691.9 EAU92555.1 - 9.4 6.8 11.6 2.5 8.6 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2497) BRCA-2_OB1 PF09103.10 EAU92556.2 - 3.6e-33 114.1 0.0 6.4e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 EAU92556.2 - 3.3e-06 26.9 0.1 1e-05 25.3 0.2 1.7 2 0 0 2 2 2 1 BRCA2, helical Peptidase_M16 PF00675.20 EAU92558.1 - 1.6e-37 128.8 0.0 2.9e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAU92558.1 - 2.1e-36 125.7 0.0 4.2e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Ceramidase PF05875.12 EAU92559.2 - 9.3e-65 218.7 0.4 1.2e-64 218.3 0.4 1.0 1 0 0 1 1 1 1 Ceramidase DUF2157 PF09925.9 EAU92559.2 - 0.083 12.7 8.3 2.3 8.0 0.1 3.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) EF_TS PF00889.19 EAU92560.1 - 1e-15 57.9 0.0 1.3e-14 54.3 0.0 2.4 2 1 1 3 3 3 1 Elongation factor TS UBA PF00627.31 EAU92560.1 - 0.00012 21.9 0.2 0.00047 20.0 0.4 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Gar1 PF04410.14 EAU92561.1 - 2.4e-33 115.1 0.3 2.4e-33 115.1 0.3 2.5 2 1 0 2 2 2 1 Gar1/Naf1 RNA binding region Hid1 PF12722.7 EAU92561.1 - 1.1 7.3 2.6 1.5 6.8 2.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 EAU92561.1 - 1.4 7.4 5.1 1.9 6.9 5.1 1.1 1 0 0 1 1 1 0 Macoilin family F-box-like PF12937.7 EAU92562.1 - 0.0009 19.1 0.2 0.0026 17.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like SAS4 PF15460.6 EAU92563.1 - 1.4e-06 28.3 1.8 4.4e-06 26.7 1.8 1.8 1 1 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PCP_red PF08369.10 EAU92564.2 - 0.049 13.8 1.9 0.13 12.5 1.9 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit DUF3583 PF12126.8 EAU92564.2 - 0.2 11.1 8.4 10 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) SOBP PF15279.6 EAU92564.2 - 0.46 11.1 7.5 0.53 10.8 7.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Nucleo_P87 PF07267.11 EAU92564.2 - 0.66 8.8 7.3 0.83 8.4 7.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DHHC PF01529.20 EAU92565.2 - 8.8e-37 126.2 8.9 8.8e-37 126.2 8.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2868 PF11067.8 EAU92566.2 - 0.015 14.9 1.3 0.015 14.9 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) CENP-F_leu_zip PF10473.9 EAU92566.2 - 0.03 14.4 14.3 1.1 9.2 9.3 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 EAU92566.2 - 0.097 11.3 14.0 0.2 10.2 14.0 1.4 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.6 EAU92566.2 - 0.27 11.7 8.3 10 6.6 4.0 2.7 2 0 0 2 2 2 0 Snapin/Pallidin Mod_r PF07200.13 EAU92566.2 - 0.27 11.3 14.9 0.92 9.6 9.4 2.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Vac_Fusion PF02346.16 EAU92566.2 - 0.34 10.5 5.2 0.33 10.6 1.0 2.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 RNase_HII PF01351.18 EAU92566.2 - 0.37 10.6 4.3 3.3 7.5 0.2 3.0 2 1 0 2 2 2 0 Ribonuclease HII CENP-Q PF13094.6 EAU92566.2 - 0.41 10.8 14.8 0.83 9.8 9.3 2.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit XhlA PF10779.9 EAU92566.2 - 0.54 10.5 0.0 0.54 10.5 0.0 3.5 2 1 2 4 4 4 0 Haemolysin XhlA DUF1664 PF07889.12 EAU92566.2 - 2.4 8.2 13.0 0.8 9.7 4.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EAU92566.2 - 5.3 7.2 11.6 6.6 6.9 3.7 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Med9 PF07544.13 EAU92566.2 - 7.3 6.8 15.2 2.3 8.3 0.3 3.1 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CutC PF03932.14 EAU92567.2 - 2.5e-39 134.9 0.0 3.3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 CutC family Cyt-b5 PF00173.28 EAU92568.2 - 3.7e-05 23.8 0.0 0.0001 22.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EAU92568.2 - 3.8e-05 23.7 2.3 7.9e-05 22.6 2.3 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Methyltransf_25 PF13649.6 EAU92569.1 - 7.9e-10 39.3 0.0 6.2e-09 36.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU92569.1 - 6.2e-09 35.9 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU92569.1 - 3.2e-07 30.2 0.0 1.9e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU92569.1 - 4.4e-07 30.4 0.0 1.1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU92569.1 - 1.3e-05 25.9 0.0 3.5e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EAU92569.1 - 0.00022 20.7 0.0 0.001 18.6 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 EAU92569.1 - 0.0041 17.3 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EAU92569.1 - 0.02 14.2 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EAU92569.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EAU92569.1 - 0.12 11.8 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Lin-8 PF03353.15 EAU92569.1 - 1.5 8.3 4.6 2.1 7.8 4.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Adaptin_N PF01602.20 EAU92570.2 - 5.1e-109 365.2 0.4 8e-109 364.6 0.4 1.2 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EAU92570.2 - 2.7e-13 50.3 1.6 2.1e-10 40.9 0.0 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EAU92570.2 - 2.2e-06 28.0 0.4 0.0035 17.7 0.0 4.9 5 1 2 7 7 7 3 HEAT repeats HEAT PF02985.22 EAU92570.2 - 5.2e-06 26.3 8.5 0.06 13.6 0.2 5.6 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 EAU92570.2 - 0.00031 20.9 0.6 0.47 10.6 0.0 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 EAU92570.2 - 0.0029 17.7 3.2 4.9 7.3 0.0 4.6 3 1 1 4 4 4 1 V-ATPase subunit H Nipped-B_C PF12830.7 EAU92570.2 - 0.017 15.0 1.8 2.2 8.2 0.1 3.4 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 EAU92570.2 - 0.027 15.0 7.0 2.9 8.5 0.0 5.8 7 0 0 7 7 7 0 HEAT-like repeat Cnd3 PF12719.7 EAU92570.2 - 0.073 12.3 0.5 4.6 6.4 0.1 3.0 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Telomere_reg-2 PF10193.9 EAU92570.2 - 1.2 9.6 5.0 29 5.2 0.1 4.0 4 0 0 4 4 4 0 Telomere length regulation protein DnaG_DnaB_bind PF08278.11 EAU92570.2 - 1.8 9.2 7.3 3.5 8.3 0.0 4.1 4 1 1 5 5 5 0 DNA primase DnaG DnaB-binding RhoGEF PF00621.20 EAU92571.2 - 6.1e-08 33.1 0.0 1.8e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 RhoGEF domain Exo84_C PF16528.5 EAU92572.2 - 1.2e-39 136.3 0.1 3.7e-39 134.7 0.1 1.9 1 1 0 1 1 1 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EAU92572.2 - 2e-16 59.8 2.1 5.5e-16 58.4 2.1 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 EAU92572.2 - 5.2e-07 29.8 1.1 1.6e-06 28.2 1.1 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.6 EAU92572.2 - 0.036 14.2 0.0 0.095 12.8 0.0 1.7 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_13 PF16652.5 EAU92572.2 - 1.1 9.1 4.7 0.89 9.4 1.6 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Sel1 PF08238.12 EAU92573.2 - 1.7e-42 142.9 23.0 4.7e-08 33.4 0.2 7.8 8 0 0 8 8 8 7 Sel1 repeat HNH_repeat PF18780.1 EAU92573.2 - 0.052 13.4 1.7 1.4 8.8 0.0 3.0 2 0 0 2 2 2 0 Homing endonuclease repeat Exo5 PF09810.9 EAU92574.2 - 1.7e-55 189.0 0.0 1.3e-52 179.5 0.0 2.8 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.20 EAU92574.2 - 0.31 11.0 4.0 1.2 9.2 2.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1349 PF07081.11 EAU92575.1 - 6.5e-19 68.3 0.0 7.6e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) MRP-S23 PF10484.9 EAU92575.1 - 0.16 12.2 0.0 0.43 10.9 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 DUF1349 PF07081.11 EAU92576.1 - 4.2e-21 75.5 0.0 5e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Isochorismatase PF00857.20 EAU92579.1 - 1.9e-25 90.0 0.5 3.6e-25 89.1 0.5 1.4 1 1 0 1 1 1 1 Isochorismatase family AFOR_N PF02730.15 EAU92579.1 - 0.0099 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain BclA_C PF18573.1 EAU92579.1 - 0.035 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 BclA C-terminal domain HA2 PF04408.23 EAU92580.2 - 1e-24 86.9 0.1 1e-24 86.9 0.1 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAU92580.2 - 3.1e-24 85.2 0.0 5.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAU92580.2 - 8.2e-14 51.9 0.0 3.2e-13 50.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EAU92580.2 - 7.7e-10 39.0 0.4 1.7e-09 37.8 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EAU92580.2 - 2e-05 24.5 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU92580.2 - 9.1e-05 22.8 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAU92580.2 - 0.0002 21.9 0.4 0.78 10.2 0.0 3.6 2 1 1 3 3 3 2 ABC transporter T2SSE PF00437.20 EAU92580.2 - 0.00049 19.2 0.0 0.0012 18.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EAU92580.2 - 0.0008 19.2 0.0 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EAU92580.2 - 0.0051 17.2 0.1 0.01 16.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAU92580.2 - 0.0058 15.9 0.0 0.015 14.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTF2 PF02136.20 EAU92581.1 - 7.3e-13 49.1 0.0 2.1e-11 44.4 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EAU92581.1 - 3.4e-10 40.1 0.0 4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Exo_endo_phos PF03372.23 EAU92582.2 - 9.4e-16 58.0 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3285 PF11688.8 EAU92582.2 - 0.17 11.8 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) DUF2244 PF10003.9 EAU92582.2 - 0.35 10.5 3.9 0.64 9.7 3.9 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Abhydrolase_3 PF07859.13 EAU92583.1 - 3.5e-46 157.7 0.2 1.3e-45 155.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU92583.1 - 4.6e-16 58.7 0.0 1.2e-15 57.3 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EAU92583.1 - 0.033 13.1 0.0 2.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Hydrolase_4 PF12146.8 EAU92583.1 - 0.047 12.9 0.0 0.095 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ctr PF04145.15 EAU92588.2 - 5.2e-05 23.9 0.8 5.2e-05 23.9 0.8 1.8 2 0 0 2 2 2 1 Ctr copper transporter family Pkinase PF00069.25 EAU92589.2 - 1.2e-25 90.4 0.0 2.7e-17 63.0 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92589.2 - 7.1e-17 61.5 0.0 6.6e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EAU92589.2 - 0.2 10.9 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribonuc_L-PSP PF01042.21 EAU92592.1 - 6.8e-37 126.2 0.1 7.6e-37 126.0 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HEAT_EZ PF13513.6 EAU92593.2 - 2.9e-05 24.4 0.4 1.8 9.2 0.0 4.8 4 0 0 4 4 4 1 HEAT-like repeat Arm PF00514.23 EAU92593.2 - 0.00092 19.2 5.1 0.012 15.7 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EAU92593.2 - 0.048 13.7 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 RRN3 PF05327.11 EAU92593.2 - 0.11 11.0 0.6 1.8 7.0 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 MCR_D PF02505.14 EAU92593.2 - 0.13 12.1 0.0 0.44 10.4 0.0 1.9 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D Nop25 PF09805.9 EAU92593.2 - 0.16 12.5 1.0 0.34 11.4 1.0 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DNA_pol_phi PF04931.13 EAU92593.2 - 4.4 5.3 10.3 11 4.0 10.3 1.6 1 0 0 1 1 1 0 DNA polymerase phi Sugar_tr PF00083.24 EAU92594.1 - 0.2 10.5 0.2 0.29 9.9 0.2 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter PAP2 PF01569.21 EAU92594.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 PAP2 superfamily Sin3a_C PF16879.5 EAU92595.2 - 4.5e-85 285.8 0.6 1.1e-82 278.0 0.0 3.5 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 EAU92595.2 - 7.3e-42 141.3 13.4 1.1e-17 63.9 0.0 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EAU92595.2 - 1.5e-40 137.2 0.3 1.8e-39 133.8 0.1 2.4 2 0 0 2 2 2 1 Sin3 family co-repressor COX5A PF02284.16 EAU92595.2 - 0.0057 16.6 0.0 0.51 10.4 0.0 2.8 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Va Rsbr_N PF08678.10 EAU92596.2 - 0.032 14.3 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Rsbr N terminal PAH PF02671.21 EAU92597.1 - 6.6e-07 29.4 0.1 9.3e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat PAH PF02671.21 EAU92598.1 - 3.9e-09 36.5 0.0 7.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat SUR7 PF06687.12 EAU92600.1 - 4.5e-15 55.9 17.2 6.2e-15 55.4 17.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Arginase PF00491.21 EAU92601.2 - 7.8e-67 225.7 0.0 1e-66 225.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family Methyltransf_25 PF13649.6 EAU92602.2 - 2.7e-13 50.4 0.0 7.5e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU92602.2 - 2.7e-11 44.0 0.0 8.3e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EAU92602.2 - 2.6e-08 33.8 0.0 4.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU92602.2 - 1.5e-06 28.1 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU92602.2 - 1e-05 26.2 0.0 5.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EAU92602.2 - 0.0016 18.0 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EAU92602.2 - 0.0019 17.6 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EAU92602.2 - 0.0038 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EAU92602.2 - 0.025 14.5 0.3 0.43 10.5 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 EAU92602.2 - 0.028 14.6 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase HTH_8 PF02954.19 EAU92602.2 - 0.12 12.2 1.6 31 4.4 0.2 3.8 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family AP3D1 PF06375.11 EAU92602.2 - 1.3 9.2 9.5 0.16 12.2 4.5 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SF3b10 PF07189.11 EAU92603.2 - 7.3e-31 106.1 0.0 8.4e-31 105.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) CDC45 PF02724.14 EAU92604.2 - 0.83 7.9 13.9 1.1 7.4 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EAU92604.2 - 0.93 7.5 10.4 1.1 7.2 10.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 EAU92604.2 - 1.2 8.3 27.8 2 7.7 27.8 1.4 1 1 0 1 1 1 0 BUD22 Nop14 PF04147.12 EAU92604.2 - 3.3 5.8 15.8 4.4 5.4 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 EAU92604.2 - 7.1 6.7 19.8 3.1 7.8 17.0 1.7 2 0 0 2 2 2 0 YL1 nuclear protein F-box-like PF12937.7 EAU92605.1 - 2.6e-06 27.2 0.0 1e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EAU92605.1 - 7.7e-05 23.0 10.8 3.5 8.2 0.1 5.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EAU92605.1 - 0.022 14.8 10.4 3.8 7.8 0.1 5.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 EAU92605.1 - 0.042 14.4 12.2 1 10.2 0.4 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat F-box PF00646.33 EAU92605.1 - 0.094 12.6 0.2 0.094 12.6 0.2 2.9 3 0 0 3 3 3 0 F-box domain YABBY PF04690.13 EAU92606.1 - 2.7e-10 41.1 0.9 2.7e-10 41.1 0.9 1.1 1 0 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 EAU92606.1 - 3.3e-05 24.4 4.0 4.1e-05 24.1 4.0 1.3 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 EAU92606.1 - 3.5e-05 24.1 1.9 5e-05 23.6 1.9 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU92606.1 - 0.00012 22.6 0.3 0.00012 22.6 0.3 1.5 2 0 0 2 2 2 1 HMG-box domain ATP-synt_J PF04911.12 EAU92606.1 - 0.15 11.6 0.8 0.24 11.0 0.8 1.3 1 0 0 1 1 1 0 ATP synthase j chain Sec1 PF00995.23 EAU92607.2 - 8.5e-114 381.9 0.0 1.1e-113 381.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SKA2 PF16740.5 EAU92607.2 - 0.096 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 cNMP_binding PF00027.29 EAU92608.1 - 7.9e-30 102.8 0.0 1.1e-14 54.2 0.0 5.4 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 EAU92608.1 - 2.7e-18 66.9 5.5 9.8e-12 45.5 4.0 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase ICL PF00463.21 EAU92609.2 - 2.8e-202 672.9 0.0 3.3e-202 672.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EAU92609.2 - 1.5e-10 40.9 0.0 3.8e-10 39.6 0.0 1.8 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Homeodomain PF00046.29 EAU92613.1 - 1.6e-45 152.7 12.9 6.5e-16 57.9 3.7 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 EAU92613.1 - 3.6e-14 52.4 3.4 3.2e-06 26.9 0.3 3.9 3 1 1 4 4 4 3 Homeobox KN domain YdaS_antitoxin PF15943.5 EAU92613.1 - 3.1e-08 33.4 0.3 0.082 12.8 0.0 3.3 3 0 0 3 3 3 3 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HOCHOB PF17943.1 EAU92613.1 - 5e-06 27.2 0.0 0.062 14.0 0.0 3.2 3 0 0 3 3 3 2 Homeobox-cysteine loop-homeobox HTH_3 PF01381.22 EAU92613.1 - 0.00015 21.7 0.3 0.82 9.8 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix Homez PF11569.8 EAU92613.1 - 0.012 15.1 0.1 11 5.5 0.0 3.3 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Phage_CI_repr PF07022.13 EAU92613.1 - 0.14 12.3 0.1 25 5.1 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain DUF1510 PF07423.11 EAU92613.1 - 0.14 12.3 0.4 19 5.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1510) RRF PF01765.19 EAU92613.1 - 0.17 11.8 0.5 11 5.9 0.4 2.2 2 0 0 2 2 2 0 Ribosome recycling factor Fumble PF03630.14 EAU92614.1 - 1.9e-130 434.9 0.0 3.1e-130 434.2 0.0 1.3 1 1 0 1 1 1 1 Fumble Adaptin_N PF01602.20 EAU92615.1 - 1.5e-115 386.8 0.0 2.1e-115 386.3 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EAU92615.1 - 6.8e-57 191.9 1.4 1.6e-56 190.6 1.4 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EAU92615.1 - 4.3e-36 123.6 0.0 9.6e-36 122.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EAU92615.1 - 1.3e-19 70.3 5.1 6e-11 42.6 0.0 6.2 3 2 3 6 6 6 4 HEAT repeats Cnd1 PF12717.7 EAU92615.1 - 9.2e-07 29.0 4.0 0.14 12.2 0.1 4.8 3 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EAU92615.1 - 0.0013 18.9 5.4 9.9 6.7 0.1 5.6 6 0 0 6 6 6 1 HEAT repeat Gly_radical PF01228.21 EAU92615.1 - 0.02 15.4 0.0 0.068 13.7 0.0 1.9 1 0 0 1 1 1 0 Glycine radical HEAT_PBS PF03130.16 EAU92615.1 - 0.087 13.5 4.2 5.7 7.9 0.0 5.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat DUF5010 PF16402.5 EAU92615.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Pkinase PF00069.25 EAU92616.1 - 3.1e-26 92.3 0.0 4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92616.1 - 1.8e-13 50.4 0.0 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU92616.1 - 2.3e-09 36.5 0.1 3.6e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU92616.1 - 0.0012 18.8 0.0 0.0077 16.2 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EAU92616.1 - 0.023 13.7 0.1 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EAU92616.1 - 0.036 13.4 0.4 0.13 11.6 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_1 PF01644.17 EAU92617.2 - 1.7e-72 242.7 0.5 2.7e-72 242.0 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EAU92617.2 - 6.6e-28 96.5 0.0 2.1e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EAU92617.2 - 6.1e-24 84.5 0.2 9.1e-20 70.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EAU92617.2 - 1e-06 28.8 0.1 1e-06 28.8 0.1 2.4 1 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_hydro_16 PF00722.21 EAU92620.1 - 2.4e-05 23.9 0.0 5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BAG PF02179.16 EAU92621.1 - 1.4e-08 35.0 0.0 4.8e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 BAG domain Exo5 PF09810.9 EAU92621.1 - 4.2 6.8 5.5 0.33 10.4 0.3 1.8 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Nuf2 PF03800.14 EAU92622.2 - 2.7e-33 115.0 0.1 2.7e-33 115.0 0.1 2.3 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EAU92622.2 - 2.3e-32 111.5 26.0 2.3e-32 111.5 26.0 4.5 2 1 3 5 5 5 1 Designed helical repeat protein 10 domain DUF5082 PF16888.5 EAU92622.2 - 0.18 12.1 37.7 0.41 10.9 8.7 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 EAU92622.2 - 0.32 11.5 55.2 0.72 10.4 13.1 3.7 1 1 2 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 EAU92622.2 - 0.42 9.9 54.8 0.074 12.4 18.0 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 EAU92622.2 - 0.5 10.8 49.2 0.3 11.5 5.4 4.3 1 1 3 4 4 4 0 Centromere protein H (CENP-H) DUF3584 PF12128.8 EAU92622.2 - 3 5.2 51.1 0.096 10.2 21.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) YabA PF06156.13 EAU92622.2 - 7.9 7.2 40.7 14 6.4 9.4 4.6 1 1 1 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 EAU92622.2 - 8.5 5.2 53.5 1.5 7.7 13.4 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein F-box PF00646.33 EAU92623.2 - 0.081 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 F-box domain GYF PF02213.16 EAU92624.1 - 1.3e-15 56.8 2.0 3.3e-15 55.5 1.5 2.0 2 0 0 2 2 2 1 GYF domain GOLGA2L5 PF15070.6 EAU92624.1 - 0.073 11.7 0.4 0.11 11.1 0.4 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Acatn PF13000.7 EAU92625.1 - 9.6e-144 479.9 30.7 1.3e-69 235.2 18.2 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF1634 PF07843.11 EAU92625.1 - 0.056 13.5 0.2 7.6 6.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) DUF3671 PF12420.8 EAU92625.1 - 0.16 12.1 1.4 0.67 10.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function p450 PF00067.22 EAU92626.1 - 1.4e-56 192.2 0.0 1.9e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4328 PF14219.6 EAU92627.2 - 0.088 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Syndecan PF01034.20 EAU92627.2 - 0.14 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain ATP11 PF06644.11 EAU92629.2 - 4.3e-84 282.5 0.5 4.3e-84 282.5 0.5 1.9 1 1 1 2 2 2 1 ATP11 protein TMCO5 PF14992.6 EAU92629.2 - 3.1 7.3 10.9 4.3 6.8 10.9 1.2 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.19 EAU92629.2 - 3.1 5.6 5.0 3.9 5.3 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAT1 PF06391.13 EAU92629.2 - 3.3 7.5 17.4 5.9 6.7 17.4 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 ERM PF00769.19 EAU92629.2 - 3.3 7.4 26.8 6.5 6.5 26.5 1.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GREB1 PF15782.5 EAU92629.2 - 9.5 3.2 11.9 12 2.9 11.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer BPL_LplA_LipB PF03099.19 EAU92630.2 - 2.7e-06 27.3 0.0 9.1e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ammonium_transp PF00909.21 EAU92631.2 - 1.6e-113 379.4 25.5 1.9e-113 379.2 25.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tim17 PF02466.19 EAU92631.2 - 5 7.5 10.1 10 6.5 7.0 3.0 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Prenylcys_lyase PF07156.14 EAU92632.2 - 5e-68 229.9 0.0 7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EAU92632.2 - 2.3e-08 34.1 0.0 6.2e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EAU92632.2 - 2.6e-08 33.6 0.0 3.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EAU92632.2 - 7e-06 25.9 0.7 0.00012 21.8 0.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EAU92632.2 - 0.00098 18.4 0.0 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU92632.2 - 0.018 15.0 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding F-box-like PF12937.7 EAU92633.2 - 1.1e-05 25.2 0.4 1.1e-05 25.2 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU92633.2 - 4.2e-05 23.3 0.2 0.00013 21.7 0.2 1.9 1 0 0 1 1 1 1 F-box domain DUF2584 PF10763.9 EAU92633.2 - 0.0062 16.7 0.0 0.16 12.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2584) DLH PF01738.18 EAU92634.2 - 8e-14 51.7 0.1 1e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF4311 PF14188.6 EAU92636.1 - 0.014 15.2 0.6 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4311) VirD1 PF07328.11 EAU92636.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Las1 PF04031.13 EAU92637.2 - 5.5e-47 159.7 0.2 1.3e-46 158.5 0.2 1.7 1 0 0 1 1 1 1 Las1-like tRNA-synt_His PF13393.6 EAU92637.2 - 0.1 11.8 0.0 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Histidyl-tRNA synthetase SprB PF13573.6 EAU92638.2 - 0.025 14.4 1.1 0.052 13.3 0.1 2.2 2 0 0 2 2 2 0 SprB repeat Hexapep_2 PF14602.6 EAU92638.2 - 0.16 11.7 0.4 0.3 10.9 0.4 1.4 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase Ysc84 PF04366.12 EAU92639.2 - 9.3e-38 128.9 0.1 1.7e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_2 PF07653.17 EAU92639.2 - 0.016 14.9 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Variant SH3 domain SH3_9 PF14604.6 EAU92639.2 - 0.019 14.8 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain PIF1 PF05970.14 EAU92642.2 - 1.6e-57 195.3 0.0 1.8e-45 155.7 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EAU92642.2 - 2.7e-19 69.6 0.0 9.2e-19 67.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU92642.2 - 3e-09 37.4 0.0 7.5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EAU92642.2 - 1e-05 25.8 0.2 8.7e-05 22.8 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EAU92642.2 - 4.5e-05 23.9 0.1 0.00026 21.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 EAU92642.2 - 0.00017 21.4 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EAU92642.2 - 0.0009 17.3 0.0 0.0016 16.4 0.0 1.3 1 0 0 1 1 1 1 Helicase NACHT PF05729.12 EAU92642.2 - 0.0031 17.4 0.0 0.011 15.7 0.0 1.9 1 1 0 1 1 1 1 NACHT domain PhoH PF02562.16 EAU92642.2 - 0.0041 16.6 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein AAA_7 PF12775.7 EAU92642.2 - 0.0051 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region SH3_13 PF18335.1 EAU92642.2 - 0.0068 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_5 PF07728.14 EAU92642.2 - 0.0095 15.9 0.1 2.7 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DEAD PF00270.29 EAU92642.2 - 0.014 15.2 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.27 EAU92642.2 - 0.014 15.9 0.6 0.042 14.3 0.1 2.1 2 0 0 2 2 1 0 ABC transporter AAA PF00004.29 EAU92642.2 - 0.02 15.3 0.1 0.072 13.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EAU92642.2 - 0.023 13.8 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EAU92642.2 - 0.033 13.9 0.1 6.5 6.4 0.0 3.3 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EAU92642.2 - 0.049 13.5 0.1 0.22 11.4 0.1 2.1 1 1 0 1 1 1 0 Helicase AAA_29 PF13555.6 EAU92642.2 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EAU92642.2 - 0.086 12.7 0.0 0.33 10.8 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EAU92642.2 - 0.098 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EAU92642.2 - 0.15 11.9 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 EAU92642.2 - 0.2 12.0 0.0 0.74 10.2 0.0 2.1 1 1 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EAU92642.2 - 1.2 8.9 0.0 1.2 8.9 0.0 3.0 4 0 0 4 4 4 0 AAA domain ABC_membrane PF00664.23 EAU92643.2 - 4.5e-50 170.8 26.0 8.2e-28 97.8 5.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EAU92643.2 - 9.8e-36 123.3 0.0 2e-17 64.0 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EAU92643.2 - 4.3e-07 29.6 0.3 0.31 10.4 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EAU92643.2 - 4.4e-06 27.2 0.1 0.074 13.4 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EAU92643.2 - 6.8e-06 25.8 0.0 0.038 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EAU92643.2 - 1.1e-05 25.4 2.5 0.039 13.8 0.3 3.4 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAU92643.2 - 1.6e-05 25.5 0.1 0.0092 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAU92643.2 - 8e-05 22.3 0.2 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EAU92643.2 - 8.1e-05 21.8 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EAU92643.2 - 0.00016 21.7 0.2 0.15 12.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EAU92643.2 - 0.00048 19.9 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EAU92643.2 - 0.00076 19.4 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 EAU92643.2 - 0.0049 16.9 0.9 7.2 6.6 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EAU92643.2 - 0.0052 16.9 1.2 0.15 12.1 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Adeno_IVa2 PF02456.15 EAU92643.2 - 0.0058 15.5 0.3 0.053 12.3 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.18 EAU92643.2 - 0.0061 15.9 0.1 3 7.1 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.6 EAU92643.2 - 0.0064 16.8 0.0 0.9 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EAU92643.2 - 0.012 15.4 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EAU92643.2 - 0.017 15.3 0.2 7.8 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EAU92643.2 - 0.021 14.4 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EAU92643.2 - 0.029 14.4 0.2 6.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DPM3 PF08285.11 EAU92643.2 - 0.033 14.4 1.1 0.51 10.6 0.8 3.0 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pox_A32 PF04665.12 EAU92643.2 - 0.059 12.8 0.8 12 5.3 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.29 EAU92643.2 - 0.061 13.1 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase cobW PF02492.19 EAU92643.2 - 0.12 11.9 0.9 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PhoH PF02562.16 EAU92643.2 - 0.14 11.6 0.0 6.5 6.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 EAU92643.2 - 0.16 12.5 0.0 23 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EAU92643.2 - 0.18 11.5 0.1 4.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EAU92643.2 - 0.2 11.8 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EAU92643.2 - 0.21 11.4 0.6 7.9 6.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EAU92643.2 - 0.22 11.4 1.4 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain RRM_1 PF00076.22 EAU92644.2 - 2.5e-14 52.8 0.1 3.5e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EAU92644.2 - 2.9e-08 33.4 1.0 5.1e-08 32.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EAU92644.2 - 0.00021 21.0 0.7 0.0005 19.8 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EAU92644.2 - 0.00042 19.9 1.4 0.0011 18.6 1.4 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EAU92644.2 - 0.00089 19.2 0.1 0.002 18.0 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EAU92644.2 - 0.061 13.1 0.1 0.095 12.5 0.1 1.3 1 0 0 1 1 1 0 Zinc knuckle RRM_7 PF16367.5 EAU92644.2 - 0.086 13.0 0.0 0.19 11.9 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif RRM_3 PF08777.11 EAU92644.2 - 0.092 12.8 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Glyco_transf_28 PF03033.20 EAU92646.2 - 9.5e-31 106.7 0.0 2.8e-30 105.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EAU92646.2 - 5.2e-20 71.4 0.8 1.8e-14 53.6 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 EAU92646.2 - 1e-11 45.2 0.3 8.3e-11 42.3 0.5 2.3 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 EAU92646.2 - 2e-06 28.1 0.0 4.5e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain UDPGT PF00201.18 EAU92646.2 - 5.3e-05 22.2 0.1 0.00014 20.8 0.1 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 EAU92646.2 - 0.0012 19.3 1.1 0.17 12.3 0.4 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EAU92646.2 - 0.0051 17.1 0.2 0.015 15.6 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain 2OG-FeII_Oxy PF03171.20 EAU92647.2 - 0.002 18.6 0.0 0.0098 16.4 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EAU92647.2 - 0.003 18.3 0.0 0.0058 17.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MMR_HSR1_Xtn PF16897.5 EAU92651.2 - 1.1e-35 121.9 1.6 1.6e-35 121.3 1.6 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EAU92651.2 - 1.5e-19 70.2 0.1 3.2e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU92651.2 - 9.4e-11 41.5 0.0 2e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B MCM PF00493.23 EAU92651.2 - 0.019 14.0 0.1 0.06 12.4 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain Dynamin_N PF00350.23 EAU92651.2 - 0.023 14.8 0.1 0.98 9.4 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.6 EAU92651.2 - 0.049 14.0 0.2 0.096 13.1 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain CENP-B_dimeris PF09026.10 EAU92654.2 - 0.24 11.8 8.8 0.54 10.7 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EAU92654.2 - 0.37 10.1 4.7 0.56 9.5 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein B-block_TFIIIC PF04182.12 EAU92655.2 - 6.3e-09 35.9 0.8 1.4e-05 25.2 0.0 3.3 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC HTH_27 PF13463.6 EAU92655.2 - 0.001 19.5 0.3 0.011 16.2 0.1 3.0 3 0 0 3 3 3 1 Winged helix DNA-binding domain HrpB7 PF09486.10 EAU92655.2 - 0.041 14.3 1.0 0.14 12.5 1.0 1.9 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HTH_20 PF12840.7 EAU92655.2 - 0.052 13.6 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Herpes_IE1 PF07340.11 EAU92655.2 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein HTH_24 PF13412.6 EAU92655.2 - 0.13 11.8 6.4 0.66 9.6 0.0 4.3 5 0 0 5 5 5 0 Winged helix-turn-helix DNA-binding PRELI PF04707.14 EAU92656.1 - 1.2e-37 129.1 0.1 1.5e-37 128.9 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family ABC_membrane_2 PF06472.15 EAU92657.2 - 2.2e-82 276.5 0.5 2.9e-82 276.1 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EAU92657.2 - 2.2e-16 60.6 0.0 4.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EAU92657.2 - 9.9e-05 22.3 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EAU92657.2 - 0.015 15.8 0.0 0.015 15.8 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 EAU92657.2 - 0.033 13.9 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EAU92657.2 - 0.036 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain SMC_N PF02463.19 EAU92657.2 - 0.041 13.3 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EAU92657.2 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4258 PF14076.6 EAU92657.2 - 0.092 13.1 0.2 0.97 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) AAA_27 PF13514.6 EAU92657.2 - 0.093 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EAU92657.2 - 0.1 13.0 0.2 2.4 8.6 0.1 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NT5C PF06941.12 EAU92658.2 - 5.5e-11 42.7 0.1 3.4e-10 40.1 0.1 2.1 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 EAU92658.2 - 6.4e-06 26.4 0.0 1.5e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 EAU92658.2 - 9.6e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 EAU92658.2 - 0.0037 17.7 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAU92658.2 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pro_CA PF00484.19 EAU92659.1 - 2.4e-06 27.9 0.1 0.00027 21.3 0.0 2.2 1 1 1 2 2 2 2 Carbonic anhydrase RINT1_TIP1 PF04437.13 EAU92660.2 - 1.6e-100 337.4 0.0 1.2e-98 331.2 0.0 2.2 2 0 0 2 2 2 2 RINT-1 / TIP-1 family VWA PF00092.28 EAU92660.2 - 0.0013 19.0 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain TRCF PF03461.15 EAU92660.2 - 0.15 12.5 0.0 0.6 10.5 0.0 2.1 1 0 0 1 1 1 0 TRCF domain FliT PF05400.13 EAU92660.2 - 0.47 11.3 8.5 0.086 13.7 1.3 3.0 1 1 1 2 2 2 0 Flagellar protein FliT Rbsn PF11464.8 EAU92660.2 - 2.9 7.7 4.4 0.93 9.3 0.5 2.2 2 0 0 2 2 2 0 Rabenosyn Rab binding domain TPR_MLP1_2 PF07926.12 EAU92660.2 - 3 7.9 10.1 6.9 6.8 0.5 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4203 PF13886.6 EAU92662.1 - 8.5e-55 185.5 27.3 1.3e-54 184.9 27.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2417 PF10329.9 EAU92662.1 - 0.14 11.6 2.2 1.6 8.1 1.3 2.3 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF2157 PF09925.9 EAU92662.1 - 7 6.4 14.0 0.085 12.6 4.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Ctr PF04145.15 EAU92662.1 - 8.7 7.0 5.7 17 6.0 0.1 2.7 2 0 0 2 2 2 0 Ctr copper transporter family DUF2524 PF10732.9 EAU92664.1 - 0.032 14.5 0.3 0.047 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) PPR_2 PF13041.6 EAU92665.1 - 4e-39 132.6 0.0 6.9e-10 39.0 0.0 8.8 4 3 5 9 9 9 6 PPR repeat family PPR_3 PF13812.6 EAU92665.1 - 2.8e-27 94.6 0.0 2.8e-05 24.1 0.2 6.2 5 1 1 6 6 6 6 Pentatricopeptide repeat domain PPR PF01535.20 EAU92665.1 - 7.6e-21 72.8 5.0 0.02 15.1 0.0 11.4 12 0 0 12 12 12 5 PPR repeat PPR_1 PF12854.7 EAU92665.1 - 7.2e-10 38.4 8.7 0.4 10.4 0.0 7.6 9 0 0 9 9 9 4 PPR repeat PPR_long PF17177.4 EAU92665.1 - 8.2e-09 35.1 0.0 4.4e-05 22.9 0.0 3.4 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Vitellogenin_N PF01347.22 EAU92665.1 - 0.00064 18.2 0.0 0.00075 18.0 0.0 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region Pro_isomerase PF00160.21 EAU92666.2 - 2.5e-44 151.3 0.0 4.2e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EAU92666.2 - 0.011 15.9 0.3 0.027 14.6 0.0 1.8 2 0 0 2 2 2 0 U-box domain Rtf2 PF04641.12 EAU92666.2 - 0.017 14.5 0.0 0.11 11.9 0.0 2.1 1 1 0 1 1 1 0 Rtf2 RING-finger zf-NOSIP PF15906.5 EAU92666.2 - 0.09 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EAU92666.2 - 0.18 11.6 0.3 5.6 6.9 0.1 2.8 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Snf7 PF03357.21 EAU92667.2 - 4e-21 75.4 5.0 4.7e-21 75.1 5.0 1.0 1 0 0 1 1 1 1 Snf7 PP2C PF00481.21 EAU92668.2 - 1.4e-35 123.2 0.0 1.4e-33 116.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C G_glu_transpept PF01019.21 EAU92669.2 - 7.6e-137 457.2 0.0 1.1e-136 456.6 0.0 1.2 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Tox-REase-3 PF15647.6 EAU92669.2 - 0.18 12.1 0.0 15 5.9 0.0 2.4 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 Prefoldin_2 PF01920.20 EAU92670.1 - 1.8e-22 79.3 11.6 2.3e-22 79.0 11.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EAU92670.1 - 0.0031 17.5 2.2 0.0041 17.1 1.9 1.3 1 1 0 1 1 1 1 Prefoldin subunit FPP PF05911.11 EAU92670.1 - 0.013 13.8 9.3 0.014 13.6 9.3 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4139 PF13598.6 EAU92670.1 - 0.014 15.1 1.4 0.016 15.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Tup_N PF08581.10 EAU92670.1 - 0.03 14.6 8.1 0.44 10.9 3.2 3.2 1 1 1 2 2 2 0 Tup N-terminal End3 PF12761.7 EAU92670.1 - 0.044 14.0 7.1 0.061 13.5 7.1 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Rx_N PF18052.1 EAU92670.1 - 0.06 13.6 0.6 0.06 13.6 0.6 2.1 2 0 0 2 2 2 0 Rx N-terminal domain GAS PF13851.6 EAU92670.1 - 0.1 12.0 11.1 0.75 9.1 1.8 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EAU92670.1 - 0.14 12.7 15.5 0.097 13.2 4.1 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region Tropomyosin_1 PF12718.7 EAU92670.1 - 0.45 10.7 11.6 2.1 8.5 2.1 2.2 2 0 0 2 2 2 0 Tropomyosin like XhlA PF10779.9 EAU92670.1 - 0.58 10.4 4.6 0.16 12.2 1.2 1.9 2 1 0 2 2 2 0 Haemolysin XhlA HIP1_clath_bdg PF16515.5 EAU92670.1 - 0.92 10.2 10.7 2.1 9.0 1.4 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 EAU92670.1 - 1.2 9.2 16.0 0.81 9.8 4.7 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EAU92670.1 - 1.7 7.7 7.6 2 7.4 7.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 EAU92670.1 - 2.1 8.8 10.2 1.1 9.7 1.7 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 EAU92670.1 - 2.2 8.8 9.2 0.69 10.4 4.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EAU92670.1 - 2.3 8.0 9.7 1.8 8.3 3.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 EAU92670.1 - 2.3 8.2 12.5 2 8.4 3.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 EAU92670.1 - 2.9 8.1 8.7 6.1 7.0 8.7 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 EAU92670.1 - 4.2 8.1 9.6 4.9 7.8 2.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 EAU92670.1 - 4.7 7.7 6.2 5.9 7.4 1.1 2.9 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 EAU92670.1 - 7.1 6.9 11.2 2.1 8.6 1.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MFS_1 PF07690.16 EAU92671.2 - 1.2e-38 133.0 34.0 1.2e-38 133.0 34.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Ribosomal_S17 PF00366.20 EAU92671.2 - 7.3e-20 70.8 1.4 7.3e-20 70.8 1.4 2.3 2 0 0 2 2 2 1 Ribosomal protein S17 Sugar_tr PF00083.24 EAU92671.2 - 9e-12 44.6 1.1 9e-12 44.6 1.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EAU92671.2 - 4.6e-09 35.2 0.4 4.6e-09 35.2 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EAU92671.2 - 1.5e-05 24.4 1.0 1.5e-05 24.4 1.0 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB FPN1 PF06963.12 EAU92671.2 - 0.051 12.1 0.0 0.085 11.4 0.0 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) ANAPC4_WD40 PF12894.7 EAU92672.2 - 1.4e-11 44.6 0.0 0.00027 21.2 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU92672.2 - 5.2e-05 23.9 13.3 0.0066 17.3 0.3 6.5 5 1 1 6 6 6 2 WD domain, G-beta repeat Peptidase_S9_N PF02897.15 EAU92672.2 - 0.081 11.7 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_M41 PF01434.18 EAU92673.1 - 1.4e-64 217.5 0.0 2.1e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EAU92673.1 - 3.5e-42 144.0 0.0 7.8e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EAU92673.1 - 6.9e-13 48.2 0.0 2.2e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EAU92673.1 - 4.6e-09 36.6 0.0 1.1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 EAU92673.1 - 0.0037 17.3 0.3 0.21 11.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU92673.1 - 0.0048 17.3 0.2 0.12 12.7 0.1 2.7 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EAU92673.1 - 0.0057 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EAU92673.1 - 0.027 14.2 0.0 0.073 12.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EAU92673.1 - 0.028 14.6 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EAU92673.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EAU92673.1 - 0.038 14.3 0.1 0.41 10.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain CHAD PF05235.14 EAU92673.1 - 0.083 12.9 0.2 0.083 12.9 0.2 1.9 2 0 0 2 2 2 0 CHAD domain FUSC PF04632.12 EAU92673.1 - 0.29 9.6 1.7 1.5 7.3 0.4 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Pex14_N PF04695.13 EAU92673.1 - 3.4 8.3 10.7 9.5 6.9 10.7 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.16 EAU92674.2 - 2.3e-31 109.0 44.0 3.8e-26 91.8 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_U4 PF03419.13 EAU92674.2 - 1.9 7.7 7.0 0.72 9.1 0.2 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA UreD PF01774.17 EAU92675.1 - 6.5e-64 215.7 0.1 8.2e-64 215.4 0.1 1.1 1 0 0 1 1 1 1 UreD urease accessory protein NRDE-2 PF08424.10 EAU92677.2 - 3.2e-71 240.1 1.6 3.2e-71 240.1 1.6 2.1 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EAU92677.2 - 0.083 13.8 22.0 1.4 9.9 0.0 8.6 9 2 1 10 10 10 0 Tetratricopeptide repeat CENP-N PF05238.13 EAU92677.2 - 0.73 9.1 7.1 1.5 8.1 7.1 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like TPR_19 PF14559.6 EAU92677.2 - 1.7 9.2 4.0 19 5.8 0.3 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0113_N PF17833.1 EAU92678.1 - 1.3e-30 105.8 0.0 2.1e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EAU92678.1 - 6.2e-27 93.7 0.0 1.4e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain PP1 PF07430.11 EAU92678.1 - 0.047 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Sec39 PF08314.11 EAU92679.1 - 7e-116 388.5 0.0 8.8e-116 388.2 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DHR-2 PF06920.13 EAU92679.1 - 0.006 15.3 0.1 0.0097 14.6 0.1 1.2 1 0 0 1 1 1 1 Dock homology region 2 FlxA PF14282.6 EAU92680.2 - 0.099 12.6 1.8 0.25 11.4 1.8 1.6 1 0 0 1 1 1 0 FlxA-like protein Cgr1 PF03879.14 EAU92681.1 - 2.3e-30 105.1 20.8 2.6e-30 105.0 20.8 1.0 1 0 0 1 1 1 1 Cgr1 family P66_CC PF16563.5 EAU92681.1 - 0.05 13.2 16.8 0.13 11.9 4.6 2.4 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 AP1AR PF15745.5 EAU92681.1 - 0.2 11.3 10.0 0.25 11.0 10.0 1.1 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein FAM199X PF15814.5 EAU92681.1 - 0.39 9.7 3.5 0.44 9.6 3.5 1.1 1 0 0 1 1 1 0 Protein family FAM199X Atg14 PF10186.9 EAU92681.1 - 2.5 7.1 12.1 2.8 6.9 12.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RF-1 PF00472.20 EAU92681.1 - 9.8 6.1 13.6 15 5.5 13.6 1.4 1 1 0 1 1 1 0 RF-1 domain Pep3_Vps18 PF05131.14 EAU92682.2 - 1.5e-47 161.2 0.0 3.4e-47 160.0 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EAU92682.2 - 2.1e-09 37.4 5.6 0.0015 18.4 0.1 3.5 2 2 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EAU92682.2 - 4.2e-05 23.9 0.0 0.00012 22.5 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EAU92682.2 - 0.0034 17.3 3.1 0.0036 17.2 1.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EAU92682.2 - 0.042 13.6 5.2 0.11 12.3 5.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EAU92682.2 - 0.097 12.7 0.8 0.27 11.3 0.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger ANAPC3 PF12895.7 EAU92682.2 - 0.11 12.7 1.0 0.32 11.2 1.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPM_phosphatase PF04536.14 EAU92682.2 - 0.12 12.5 0.9 0.26 11.5 0.1 1.9 2 0 0 2 2 2 0 TPM domain Zn_ribbon_17 PF17120.5 EAU92682.2 - 0.39 10.4 1.3 0.86 9.3 1.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TPR_1 PF00515.28 EAU92682.2 - 0.43 10.5 9.6 4.7 7.2 0.8 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EAU92682.2 - 0.44 10.9 5.4 0.29 11.5 1.7 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 EAU92682.2 - 0.94 9.4 8.1 0.091 12.6 2.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.6 EAU92682.2 - 4.3 8.1 8.5 1.7 9.3 5.3 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat Myosin_tail_1 PF01576.19 EAU92683.2 - 0.00017 19.6 63.6 0.00017 19.6 63.6 3.2 1 1 1 3 3 3 1 Myosin tail GAS PF13851.6 EAU92683.2 - 0.00034 20.0 29.3 0.00034 20.0 29.3 7.2 1 1 7 8 8 8 3 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 EAU92683.2 - 0.0014 18.7 14.8 0.0014 18.7 14.8 9.7 1 1 7 9 9 9 3 Designed helical repeat protein 10 domain Filament PF00038.21 EAU92683.2 - 0.018 14.6 122.6 0.27 10.8 24.3 5.6 1 1 3 5 5 5 0 Intermediate filament protein Spc7 PF08317.11 EAU92683.2 - 0.52 9.2 149.8 0.15 10.9 27.1 7.2 1 1 5 7 7 7 0 Spc7 kinetochore protein DUF3584 PF12128.8 EAU92683.2 - 0.56 7.7 136.8 0.068 10.7 51.5 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) TSC22 PF01166.18 EAU92683.2 - 0.73 10.2 0.0 0.73 10.2 0.0 7.9 7 2 0 8 8 8 0 TSC-22/dip/bun family ATG16 PF08614.11 EAU92683.2 - 3.5 7.8 167.2 0.056 13.7 18.5 8.4 2 1 6 8 8 8 0 Autophagy protein 16 (ATG16) Mito_carr PF00153.27 EAU92684.1 - 5.1e-28 96.8 5.2 7.4e-14 51.4 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.12 EAU92685.1 - 2.8e-11 43.5 2.3 4.7e-11 42.7 2.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family SDF PF00375.18 EAU92685.1 - 0.00042 19.4 1.6 0.00071 18.7 1.6 1.3 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4229 PF14012.6 EAU92685.1 - 0.17 12.0 0.4 0.17 12.0 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) LCCL PF03815.19 EAU92688.1 - 2.6e-12 46.7 0.0 5e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Wzy_C PF04932.15 EAU92688.1 - 3.7 7.2 11.0 9.1 5.9 1.2 3.3 3 0 0 3 3 3 0 O-Antigen ligase Phi-29_GP4 PF05464.11 EAU92689.1 - 0.23 11.8 0.0 0.4 11.0 0.0 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Seipin PF06775.14 EAU92690.1 - 4.7e-21 75.8 0.0 1.7e-20 73.9 0.0 1.7 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Fun_ATP-synt_8 PF05933.13 EAU92690.1 - 1.3 9.2 4.6 0.83 9.9 0.5 2.2 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) SH3BGR PF04908.15 EAU92691.2 - 1.3e-12 47.7 0.1 4.5e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein LMWPc PF01451.21 EAU92692.1 - 2.8e-37 128.3 0.0 3.1e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PTS_IIB PF02302.17 EAU92692.1 - 0.051 14.3 0.1 0.17 12.6 0.1 1.8 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Aldedh PF00171.22 EAU92693.2 - 3.1e-131 438.1 0.0 3.7e-131 437.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EAU92693.2 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Rap1-DNA-bind PF09197.10 EAU92694.2 - 0.076 13.6 7.0 0.24 12.0 0.7 3.0 2 1 1 3 3 3 0 Rap1, DNA-binding PQ-loop PF04193.14 EAU92694.2 - 0.14 11.9 0.4 0.26 11.1 0.4 1.3 1 0 0 1 1 1 0 PQ loop repeat GDI PF00996.18 EAU92695.2 - 1.8e-223 741.8 0.1 2.1e-223 741.6 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rav1p_C PF12234.8 EAU92696.1 - 6.1e-200 665.8 0.1 8.2e-200 665.4 0.1 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal DUF2793 PF10983.8 EAU92696.1 - 0.097 12.6 0.8 0.32 10.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) Fasciclin PF02469.22 EAU92697.2 - 1.2e-69 232.4 0.0 7e-17 61.8 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.27 EAU92697.2 - 2.5e-65 216.4 4.0 1.4e-21 76.2 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein NAT PF04768.13 EAU92698.1 - 3.7e-35 121.1 0.0 3.6e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase F-box-like PF12937.7 EAU92699.2 - 6.5e-07 29.1 0.7 1.6e-06 27.9 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92699.2 - 1.1e-06 28.4 1.0 3.1e-06 26.9 1.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EAU92699.2 - 0.022 14.6 0.4 0.047 13.6 0.4 1.5 1 0 0 1 1 1 0 F-box UQ_con PF00179.26 EAU92700.2 - 1.2e-12 47.6 0.0 7.7e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme SKN1 PF03935.15 EAU92701.2 - 3.8e-185 616.1 0.5 4.4e-185 615.9 0.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SNAPc_SNAP43 PF09808.9 EAU92702.2 - 4.4e-05 23.5 0.0 6.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 CDK2AP PF09806.9 EAU92702.2 - 0.089 12.9 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ima1_N PF09779.9 EAU92703.1 - 4.6e-17 63.1 0.8 7e-17 62.6 0.8 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Gemini_mov PF01708.16 EAU92704.1 - 0.067 13.0 0.8 0.29 10.9 0.2 2.3 1 1 1 2 2 2 0 Geminivirus putative movement protein DUF3262 PF11660.8 EAU92704.1 - 0.087 13.2 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Plasmodium_Vir PF05795.11 EAU92704.1 - 0.12 11.8 0.7 0.15 11.4 0.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PARM PF17061.5 EAU92704.1 - 0.19 11.8 27.0 0.28 11.3 27.0 1.2 1 0 0 1 1 1 0 PARM DUF4366 PF14283.6 EAU92704.1 - 0.57 10.2 3.0 2.2 8.3 2.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Hepar_II_III PF07940.13 EAU92705.1 - 3.1e-10 40.1 0.4 1.1e-09 38.2 0.6 1.7 2 0 0 2 2 2 1 Heparinase II/III-like protein DUF4962 PF16332.5 EAU92705.1 - 1.3e-05 23.9 0.0 2.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) FecR PF04773.13 EAU92705.1 - 0.19 12.4 0.3 0.36 11.5 0.3 1.4 1 0 0 1 1 1 0 FecR protein Homeodomain PF00046.29 EAU92707.2 - 1.7e-06 27.8 0.2 3.3e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 Homeodomain KAR9 PF08580.10 EAU92707.2 - 0.013 14.1 9.9 0.014 13.9 9.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Sec3_C PF09763.9 EAU92708.2 - 3.7e-162 541.3 3.7 7.3e-162 540.3 3.7 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EAU92708.2 - 2.5e-19 69.2 0.0 1.5e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 EAU92708.2 - 0.00034 19.5 2.4 0.00096 18.0 2.4 1.7 1 0 0 1 1 1 1 Vps52 / Sac2 family WhiA_N PF10298.9 EAU92708.2 - 0.047 13.8 0.4 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain TB2_DP1_HVA22 PF03134.19 EAU92709.2 - 2.4e-26 91.4 6.5 2.4e-26 91.4 6.5 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family M20_dimer PF07687.14 EAU92709.2 - 0.085 12.8 0.4 0.17 11.8 0.4 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Zn_clus PF00172.18 EAU92710.2 - 2.2e-07 30.9 10.9 4e-07 30.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EAU92710.2 - 7.4e-07 28.5 0.0 1.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ThrE PF06738.12 EAU92711.2 - 3.7e-37 128.0 10.3 4.7e-37 127.7 10.3 1.1 1 0 0 1 1 1 1 Putative threonine/serine exporter DUF4574 PF15141.6 EAU92711.2 - 0.058 13.3 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Esterase PF00756.20 EAU92713.2 - 2.9e-43 148.3 0.0 3.4e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EAU92713.2 - 0.025 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EAU92713.2 - 0.04 13.2 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EAU92713.2 - 0.087 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Ribonucleas_3_3 PF14622.6 EAU92714.2 - 2.3e-11 44.0 0.0 3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EAU92714.2 - 1.3e-05 25.8 0.0 3.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 EAU92714.2 - 4.6e-05 24.0 0.0 0.00013 22.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain SNF2_N PF00176.23 EAU92715.2 - 3.7e-59 200.2 0.1 3.2e-34 118.2 0.0 2.3 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU92715.2 - 2.7e-14 53.4 0.0 9.4e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EAU92715.2 - 0.00027 20.9 4.7 0.00077 19.4 4.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Complex1_LYR PF05347.15 EAU92715.2 - 0.034 14.2 0.2 0.08 13.0 0.2 1.6 1 0 0 1 1 1 0 Complex 1 protein (LYR family) zf-RING_2 PF13639.6 EAU92715.2 - 0.23 11.8 5.7 0.96 9.8 0.5 2.7 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 EAU92715.2 - 0.33 10.9 6.8 0.94 9.4 6.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EAU92715.2 - 0.61 10.0 10.2 1.2 9.1 8.8 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EAU92715.2 - 2.2 8.2 8.4 0.2 11.5 1.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EAU92715.2 - 4.8 7.3 7.9 18 5.5 7.9 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Sec8_exocyst PF04048.14 EAU92716.2 - 1.2e-31 109.5 1.1 1.2e-31 109.5 1.1 1.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EAU92716.2 - 1.5e-07 31.0 1.9 3.9e-07 29.7 1.9 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EAU92716.2 - 0.093 12.5 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 EAU92716.2 - 1.4 9.0 3.9 5.9 7.0 0.4 3.5 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LIDHydrolase PF10230.9 EAU92717.2 - 2e-46 158.7 0.0 2.5e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EAU92717.2 - 1.8e-07 30.7 0.0 2.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EAU92717.2 - 3.2e-05 24.6 0.9 3.9e-05 24.4 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EAU92717.2 - 0.0018 17.9 0.1 0.0032 17.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EAU92717.2 - 0.0073 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase PGAP1 PF07819.13 EAU92717.2 - 0.014 15.1 0.1 0.056 13.2 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF1749 PF08538.10 EAU92717.2 - 0.017 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF3089 PF11288.8 EAU92717.2 - 0.035 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) SNF2_N PF00176.23 EAU92718.2 - 1.2e-55 188.7 0.1 1.8e-55 188.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU92718.2 - 3e-13 50.1 0.0 4.1e-12 46.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EAU92718.2 - 6e-10 38.8 1.0 3.8e-06 26.3 0.2 2.6 1 1 1 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 EAU92718.2 - 1.4e-07 31.3 2.2 1.4e-07 31.3 2.2 2.4 1 1 1 2 2 2 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.24 EAU92718.2 - 0.0016 18.3 7.3 0.011 15.7 0.1 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EAU92718.2 - 0.0021 18.1 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_2 PF13831.6 EAU92718.2 - 1.1 8.9 5.3 2 8.1 0.2 3.5 3 0 0 3 3 3 0 PHD-finger PHD PF00628.29 EAU92718.2 - 3.9 7.5 15.5 0.34 10.8 0.1 4.1 5 0 0 5 5 5 0 PHD-finger PGAP1 PF07819.13 EAU92719.1 - 9.1e-07 28.8 0.3 2.1e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 EAU92719.1 - 1.8e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EAU92719.1 - 0.00039 20.1 0.3 0.0071 16.0 0.3 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU92719.1 - 0.00063 20.4 3.3 0.00069 20.3 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 EAU92719.1 - 0.0028 17.2 0.1 0.0079 15.7 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.11 EAU92719.1 - 0.0097 15.3 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EAU92719.1 - 0.045 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 EAU92719.1 - 0.061 12.5 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 EAU92719.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF4337 PF14235.6 EAU92719.1 - 2.2 8.4 4.5 1.3 9.1 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Kelch_3 PF13415.6 EAU92720.2 - 3.8e-23 81.3 7.9 5.6e-06 26.5 0.0 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EAU92720.2 - 1.6e-20 72.8 15.6 7e-07 29.2 0.0 6.6 4 2 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EAU92720.2 - 1.1e-19 70.0 5.1 7.2e-06 26.1 0.9 6.0 3 2 2 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EAU92720.2 - 5.9e-19 67.6 7.5 0.00065 19.6 0.0 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EAU92720.2 - 9.1e-19 66.8 5.2 0.0027 17.3 0.0 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EAU92720.2 - 8.7e-13 47.7 12.3 0.018 15.0 2.1 6.4 5 2 0 5 5 5 4 Kelch motif SH3_19 PF18597.1 EAU92720.2 - 0.18 11.7 0.0 0.5 10.2 0.0 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain S1 PF00575.23 EAU92721.1 - 3e-54 181.3 28.6 2.4e-11 43.8 0.0 10.5 10 0 0 10 10 10 8 S1 RNA binding domain TPR_14 PF13428.6 EAU92721.1 - 6.5e-06 26.5 0.0 4.1 8.5 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EAU92721.1 - 3.7e-05 24.1 0.0 0.86 10.2 0.0 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU92721.1 - 0.00024 21.2 0.1 0.0025 18.0 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EAU92721.1 - 0.00079 19.7 0.1 2.2 8.6 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EAU92721.1 - 0.0025 18.4 0.0 4.2 8.1 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Suf PF05843.14 EAU92721.1 - 0.011 15.8 0.2 0.011 15.8 0.2 4.8 3 1 2 5 5 5 0 Suppressor of forked protein (Suf) TPR_2 PF07719.17 EAU92721.1 - 0.05 13.7 0.4 5.7 7.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EAU92721.1 - 0.067 13.9 0.1 0.18 12.5 0.1 1.8 1 0 0 1 1 1 0 Sel1 repeat TPR_6 PF13174.6 EAU92721.1 - 0.14 12.8 0.1 50 4.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SF3A2 PF16835.5 EAU92722.1 - 9.4e-37 125.3 0.1 1.4e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EAU92722.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EAU92722.1 - 0.014 15.0 0.9 0.026 14.1 0.9 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 EAU92722.1 - 0.054 13.4 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Pal1 PF08316.11 EAU92723.1 - 0.00049 20.9 2.5 0.00084 20.1 0.0 2.6 3 0 0 3 3 3 1 Pal1 cell morphology protein DUF1490 PF07371.12 EAU92723.1 - 0.17 12.0 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) Drc1-Sld2 PF11719.8 EAU92725.1 - 8.8e-15 55.2 10.3 8.8e-15 55.2 10.3 3.3 2 2 1 3 3 3 1 DNA replication and checkpoint protein PCI PF01399.27 EAU92727.1 - 1.5e-20 73.7 0.1 6.8e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EAU92727.1 - 7.4e-06 26.0 2.1 1.8e-05 24.7 2.1 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain LUC7 PF03194.15 EAU92727.1 - 0.02 14.6 1.3 0.047 13.3 0.9 1.7 1 1 0 1 1 1 0 LUC7 N_terminus MRP-S25 PF13741.6 EAU92728.1 - 3.1e-54 184.0 4.8 2.7e-52 177.6 4.8 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EAU92728.1 - 0.00017 21.8 0.6 0.00052 20.3 0.6 1.8 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 AMP-binding PF00501.28 EAU92729.2 - 1.5e-79 267.6 0.0 2e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU92729.2 - 4e-15 56.6 0.4 4e-15 56.6 0.4 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Pal1 PF08316.11 EAU92736.1 - 0.28 12.0 0.0 0.28 12.0 0.0 4.2 4 1 0 4 4 4 0 Pal1 cell morphology protein GARS_A PF01071.19 EAU92737.2 - 1.1e-79 266.7 0.0 1.8e-79 266.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EAU92737.2 - 1.8e-33 115.9 0.0 3.8e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EAU92737.2 - 2.3e-33 114.8 0.0 1.3e-32 112.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EAU92737.2 - 1.8e-30 105.0 0.9 4.4e-30 103.8 0.9 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EAU92737.2 - 3.6e-15 56.4 1.5 1.9e-14 54.1 0.7 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 EAU92737.2 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EAU92737.2 - 0.0039 16.7 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EAU92737.2 - 0.12 12.0 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Ank_2 PF12796.7 EAU92738.2 - 5.5e-09 36.5 0.0 9.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 EAU92738.2 - 1.6e-07 30.9 12.9 0.00061 19.5 3.5 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EAU92738.2 - 2.7e-07 30.8 19.7 7.1e-07 29.5 7.5 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Ank_3 PF13606.6 EAU92738.2 - 7.5e-07 29.0 0.0 0.00033 20.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EAU92738.2 - 2e-06 27.9 0.0 2.3e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EAU92738.2 - 1.5e-05 25.4 0.0 2.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH PF00642.24 EAU92738.2 - 1.8e-05 24.5 10.5 0.022 14.7 2.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EAU92738.2 - 2.5e-05 24.2 15.9 0.00016 21.6 2.3 2.8 3 0 0 3 3 3 2 Zinc finger domain Torus PF16131.5 EAU92738.2 - 5.8e-05 23.7 1.7 0.00051 20.7 0.1 2.3 2 0 0 2 2 2 1 Torus domain Ank PF00023.30 EAU92738.2 - 0.00059 20.2 0.0 0.0021 18.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_3 PF15663.5 EAU92738.2 - 0.74 10.1 1.5 2 8.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger containing family NAD_Gly3P_dh_C PF07479.14 EAU92739.2 - 1.1e-49 168.4 0.3 1.7e-49 167.8 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EAU92739.2 - 5.5e-34 117.4 0.0 1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EAU92739.2 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EAU92739.2 - 0.0004 20.9 0.0 0.0031 18.0 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EAU92739.2 - 0.0057 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EAU92739.2 - 0.0065 16.5 0.0 0.087 12.9 0.1 2.7 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EAU92739.2 - 0.012 16.2 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EAU92739.2 - 0.029 13.7 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EAU92739.2 - 0.029 14.6 0.1 5.9 7.2 0.0 2.8 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 EAU92739.2 - 0.074 12.3 0.0 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EAU92739.2 - 0.16 12.2 0.0 0.76 10.0 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain SNARE PF05739.19 EAU92740.2 - 1.5e-08 34.5 0.5 7.5e-08 32.3 0.0 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 EAU92740.2 - 2.4e-06 26.6 5.0 7e-06 25.1 5.0 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 EAU92740.2 - 8.8e-06 25.5 10.6 9.6e-05 22.1 0.5 3.1 2 1 1 3 3 3 2 Syntaxin Syntaxin-18_N PF10496.9 EAU92740.2 - 0.001 19.3 1.3 0.0021 18.3 0.1 2.1 3 0 0 3 3 2 1 SNARE-complex protein Syntaxin-18 N-terminus SlyX PF04102.12 EAU92740.2 - 0.061 14.0 1.4 0.061 14.0 1.4 3.2 2 2 0 2 2 2 0 SlyX DUF16 PF01519.16 EAU92740.2 - 0.063 13.8 9.0 0.42 11.1 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 EAU92740.2 - 0.19 12.0 6.6 0.35 11.2 0.5 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fic_N PF13784.6 EAU92740.2 - 0.29 11.2 1.9 2.1 8.5 0.1 2.8 2 1 0 2 2 2 0 Fic/DOC family N-terminal DUF4988 PF16378.5 EAU92740.2 - 0.62 9.7 4.1 8.3 6.0 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function Cor1 PF04803.12 EAU92740.2 - 0.66 10.2 5.0 0.16 12.2 0.4 2.2 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Osmo_CC PF08946.10 EAU92740.2 - 0.84 9.9 3.1 8.1 6.8 0.1 3.5 3 1 0 3 3 3 0 Osmosensory transporter coiled coil FlaC_arch PF05377.11 EAU92740.2 - 1.2 9.6 5.8 8.6 6.8 0.0 3.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 EAU92740.2 - 1.3 9.4 5.0 4.5 7.6 0.1 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EAU92740.2 - 1.3 9.0 11.9 3.7 7.6 2.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EAU92740.2 - 2.2 8.8 15.4 0.65 10.5 1.1 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein RRM_1 PF00076.22 EAU92741.1 - 2e-07 30.7 0.0 1.4e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAPEG PF01124.18 EAU92743.1 - 1.1e-20 73.9 0.3 1.3e-20 73.6 0.3 1.1 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 EAU92744.2 - 5.4e-22 78.1 0.1 8.6e-22 77.4 0.0 1.4 1 1 0 1 1 1 1 MAPEG family COX14 PF14880.6 EAU92744.2 - 0.08 12.8 1.1 0.29 11.0 1.1 2.0 1 1 0 1 1 1 0 Cytochrome oxidase c assembly WD40 PF00400.32 EAU92745.1 - 1.3e-14 54.3 7.0 1.2e-05 25.9 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EAU92745.1 - 1.5e-14 53.9 0.0 1.2e-13 51.1 0.0 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EAU92745.1 - 0.00029 21.1 0.1 0.47 10.8 0.0 3.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PA28_beta PF02252.18 EAU92746.2 - 3.5e-55 185.7 1.0 4.9e-55 185.2 1.0 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 EAU92746.2 - 0.0017 18.3 0.3 0.0038 17.2 0.3 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit zf-C2H2 PF00096.26 EAU92749.2 - 3.2e-08 33.6 20.5 0.00032 21.0 1.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EAU92749.2 - 0.00013 22.3 3.8 0.00013 22.3 3.8 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EAU92749.2 - 0.0027 17.9 0.7 0.0027 17.9 0.7 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EAU92749.2 - 0.01 16.6 1.5 0.01 16.6 1.5 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 EAU92749.2 - 0.018 15.4 0.7 0.018 15.4 0.7 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EAU92749.2 - 1.1 9.6 7.5 2.4 8.5 7.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc ribbon EF-hand_6 PF13405.6 EAU92750.1 - 4.2e-12 45.0 4.8 4.1e-06 26.3 0.2 3.4 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EAU92750.1 - 6.9e-11 42.4 4.6 6.3e-05 23.3 0.1 3.1 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EAU92750.1 - 1.3e-08 33.8 6.0 0.0017 17.8 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 EAU92750.1 - 0.0039 17.5 0.0 1.3 9.4 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EAU92750.1 - 0.017 14.6 1.5 0.2 11.2 0.4 2.6 2 0 0 2 2 2 0 EF hand UPF0154 PF03672.13 EAU92750.1 - 0.036 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) DUF2666 PF10869.8 EAU92750.1 - 0.04 14.1 0.0 2.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2666) adh_short PF00106.25 EAU92751.2 - 1.8e-49 167.9 0.9 2.3e-49 167.5 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EAU92751.2 - 1.5e-38 132.7 0.4 1.9e-38 132.3 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EAU92751.2 - 3e-09 37.0 0.1 4.3e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EAU92751.2 - 5.3e-06 26.1 0.0 7.5e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EAU92751.2 - 5.5e-06 26.0 0.1 6e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EAU92751.2 - 2.1e-05 24.5 0.1 3.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EAU92751.2 - 0.0051 17.1 0.1 0.008 16.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EAU92751.2 - 0.014 14.5 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.15 EAU92751.2 - 0.024 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.13 EAU92751.2 - 0.049 13.2 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EAU92751.2 - 0.061 12.7 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PI-PLC-C1 PF16670.5 EAU92752.2 - 0.007 15.5 0.2 3.6 6.6 0.0 2.2 1 1 0 2 2 2 2 Phosphoinositide phospholipase C, Ca2+-dependent DUF1586 PF07625.11 EAU92752.2 - 1.7 8.8 3.9 3.4 7.8 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) DMPK_coil PF08826.10 EAU92753.2 - 0.002 18.2 1.9 0.0038 17.3 1.9 1.4 1 0 0 1 1 1 1 DMPK coiled coil domain like Spc42p PF11544.8 EAU92753.2 - 0.0048 16.9 0.5 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 Spindle pole body component Spc42p ZapB PF06005.12 EAU92753.2 - 0.023 15.1 1.4 0.023 15.1 1.4 1.8 2 0 0 2 2 2 0 Cell division protein ZapB DUF713 PF05218.14 EAU92753.2 - 0.059 13.1 1.1 5.4 6.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Ribosomal_L29 PF00831.23 EAU92753.2 - 0.065 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein Snapin_Pallidin PF14712.6 EAU92753.2 - 0.066 13.6 4.6 0.096 13.1 2.2 2.1 2 0 0 2 2 2 0 Snapin/Pallidin ATG16 PF08614.11 EAU92753.2 - 0.076 13.2 2.4 0.13 12.4 2.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Nnf1 PF03980.14 EAU92753.2 - 0.094 13.1 1.0 0.17 12.3 1.0 1.5 1 0 0 1 1 1 0 Nnf1 Metal_resist PF13801.6 EAU92753.2 - 0.15 12.2 0.5 0.28 11.4 0.5 1.4 1 0 0 1 1 1 0 Heavy-metal resistance bZIP_2 PF07716.15 EAU92753.2 - 0.21 11.7 3.2 0.34 11.0 3.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper SlyX PF04102.12 EAU92753.2 - 0.34 11.6 2.2 0.81 10.3 2.2 1.6 1 0 0 1 1 1 0 SlyX TMF_DNA_bd PF12329.8 EAU92753.2 - 0.41 10.7 5.2 0.19 11.7 2.0 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 EAU92753.2 - 1.5 8.9 4.7 0.97 9.6 0.8 2.0 2 0 0 2 2 2 0 bZIP transcription factor Utp11 PF03998.13 EAU92754.2 - 7.3e-73 245.5 26.8 1.3e-72 244.7 26.8 1.4 1 1 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EAU92754.2 - 0.029 13.7 0.8 0.066 12.5 0.8 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Mlf1IP PF10248.9 EAU92755.1 - 0.016 15.2 11.8 0.042 13.8 11.8 1.8 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein AIP3 PF03915.13 EAU92755.1 - 0.03 13.4 8.4 0.041 13.0 8.4 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Binary_toxB PF03495.14 EAU92755.1 - 0.09 13.0 0.3 0.68 10.2 0.3 2.4 1 1 1 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain MCU PF04678.13 EAU92755.1 - 0.21 11.6 3.1 0.43 10.7 3.1 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4572 PF15139.6 EAU92755.1 - 1 9.2 7.1 1.9 8.4 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) PAT1 PF09770.9 EAU92755.1 - 2 6.6 32.8 2.6 6.2 32.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ino80_Iec3 PF14612.6 EAU92755.1 - 4 8.0 13.6 0.91 10.1 10.2 1.6 2 0 0 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling VHS PF00790.19 EAU92756.1 - 5.5e-24 84.6 0.0 1.6e-23 83.1 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EAU92756.1 - 0.00012 22.3 2.8 0.00036 20.8 2.1 2.2 2 0 0 2 2 2 1 GAT domain GcnA_N PF18229.1 EAU92756.1 - 0.06 13.4 0.3 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain ALMT PF11744.8 EAU92756.1 - 0.06 12.2 3.9 0.084 11.7 3.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter tRNA-synt_2b PF00587.25 EAU92757.2 - 2e-23 83.3 0.0 4.2e-23 82.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EAU92757.2 - 1.1e-08 35.2 8.1 1.1e-08 35.2 8.1 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain YPEB PF14620.6 EAU92757.2 - 0.00083 18.8 1.9 0.0013 18.2 1.9 1.2 1 0 0 1 1 1 1 YpeB sporulation DUF4407 PF14362.6 EAU92757.2 - 0.0071 15.7 2.1 0.0071 15.7 2.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 EAU92757.2 - 0.057 13.9 6.6 0.14 12.7 6.6 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region tRNA-synt_2d PF01409.20 EAU92757.2 - 0.062 12.8 0.3 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) CCDC-167 PF15188.6 EAU92757.2 - 0.077 13.3 6.6 0.19 12.1 6.1 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Syntaxin-6_N PF09177.11 EAU92757.2 - 0.082 13.5 1.2 0.21 12.2 1.2 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF2205 PF10224.9 EAU92757.2 - 0.11 12.5 4.1 0.24 11.4 4.1 1.6 1 0 0 1 1 1 0 Short coiled-coil protein bZIP_2 PF07716.15 EAU92757.2 - 0.15 12.1 6.7 0.39 10.8 6.7 1.7 1 0 0 1 1 1 0 Basic region leucine zipper AAA_11 PF13086.6 EAU92757.2 - 0.17 11.6 5.2 0.27 11.0 5.2 1.2 1 0 0 1 1 1 0 AAA domain Surfac_D-trimer PF09006.11 EAU92757.2 - 0.41 10.6 4.5 0.37 10.7 1.7 2.4 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation ZapB PF06005.12 EAU92757.2 - 0.45 11.0 13.3 1.6 9.3 5.6 2.4 1 1 1 2 2 2 0 Cell division protein ZapB LMBR1 PF04791.16 EAU92757.2 - 0.63 8.9 2.4 0.88 8.4 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 EAU92757.2 - 0.75 9.8 3.0 1.5 8.8 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 EAU92757.2 - 1.3 9.4 9.1 3.1 8.2 9.1 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMPIT PF07851.13 EAU92757.2 - 3.9 6.6 5.6 6.2 6.0 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Cnn_1N PF07989.11 EAU92757.2 - 4.2 7.6 8.4 1.9 8.7 4.4 2.4 3 0 0 3 3 2 0 Centrosomin N-terminal motif 1 Rep_fac_C PF08542.11 EAU92758.2 - 2.6e-27 95.0 0.0 6.6e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EAU92758.2 - 6.1e-13 48.9 0.1 1.7e-10 40.9 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EAU92758.2 - 7.8e-13 49.0 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EAU92758.2 - 2.9e-07 30.6 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EAU92758.2 - 4.5e-07 30.4 0.0 5e-05 23.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EAU92758.2 - 1.4e-06 28.6 0.0 0.0037 17.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 EAU92758.2 - 3.1e-05 23.8 0.0 6.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EAU92758.2 - 3.2e-05 23.7 0.0 8.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EAU92758.2 - 0.00016 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 EAU92758.2 - 0.00095 18.6 0.0 0.013 14.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EAU92758.2 - 0.0046 16.0 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol3_delta PF06144.13 EAU92758.2 - 0.0088 15.8 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit NTPase_1 PF03266.15 EAU92758.2 - 0.0095 15.9 0.1 0.04 13.8 0.1 1.9 1 1 0 2 2 2 1 NTPase AAA_assoc_2 PF16193.5 EAU92758.2 - 0.011 16.1 0.0 0.028 14.8 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain AAA_24 PF13479.6 EAU92758.2 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EAU92758.2 - 0.019 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EAU92758.2 - 0.037 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 EAU92758.2 - 0.039 14.3 0.1 0.21 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU92758.2 - 0.062 13.7 0.1 0.31 11.5 0.1 2.2 1 1 0 1 1 1 0 RNA helicase TniB PF05621.11 EAU92758.2 - 0.069 12.6 0.0 12 5.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EAU92758.2 - 0.094 12.7 0.1 0.3 11.1 0.0 1.9 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EAU92758.2 - 0.17 12.4 0.1 0.53 10.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DAG1 PF05454.11 EAU92759.1 - 0.044 13.1 2.0 0.054 12.9 0.2 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RRM_1 PF00076.22 EAU92761.2 - 4e-11 42.6 0.0 3.3e-07 30.0 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EAU92761.2 - 0.012 15.7 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RNA_pol_Rpb6 PF01192.22 EAU92762.2 - 4.7e-15 55.3 0.1 7.1e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Rad51 PF08423.11 EAU92763.2 - 1.5e-96 322.6 0.3 2e-87 292.7 0.0 2.5 3 0 0 3 3 3 2 Rad51 AAA_25 PF13481.6 EAU92763.2 - 2.3e-08 33.8 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EAU92763.2 - 1.1e-05 25.9 0.3 2.6e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 EAU92763.2 - 0.00031 20.5 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_pol_A_CTD PF03118.15 EAU92763.2 - 0.0043 16.8 0.3 0.0089 15.8 0.3 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain DnaB_C PF03796.15 EAU92763.2 - 0.0068 15.8 2.3 0.0086 15.4 0.2 2.0 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA PF00004.29 EAU92763.2 - 0.018 15.5 1.7 0.048 14.1 0.3 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HHH_3 PF12836.7 EAU92763.2 - 0.03 14.6 0.1 0.13 12.5 0.1 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF1565 PF07602.11 EAU92763.2 - 0.07 12.4 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) NIR_SIR_ferr PF03460.17 EAU92763.2 - 0.13 12.1 0.2 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain CWC25 PF12542.8 EAU92764.2 - 4e-25 88.7 0.5 4e-25 88.7 0.5 4.1 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EAU92764.2 - 1.1e-13 51.1 14.6 1.1e-13 51.1 14.6 4.4 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Ion_trans PF00520.31 EAU92765.2 - 0.00015 21.1 2.8 0.00022 20.6 2.8 1.1 1 0 0 1 1 1 1 Ion transport protein DUF2244 PF10003.9 EAU92765.2 - 1.5 8.5 4.0 1.5 8.5 1.1 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) ANTH PF07651.16 EAU92767.1 - 1.1e-69 234.6 0.0 1.1e-69 234.6 0.0 3.4 4 1 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EAU92767.1 - 5.5e-55 185.8 12.0 5.5e-55 185.8 12.0 6.8 3 2 3 7 7 7 2 I/LWEQ domain TcdB_N PF12918.7 EAU92767.1 - 0.00027 21.2 2.4 0.00077 19.7 0.0 3.1 3 0 0 3 3 3 1 TcdB toxin N-terminal helical domain XkdW PF09636.10 EAU92767.1 - 7 6.8 10.0 1.5 9.0 4.9 2.6 2 0 0 2 2 2 0 XkdW protein SURF1 PF02104.15 EAU92768.2 - 1.6e-45 155.5 0.0 2e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Myb_DNA-bind_7 PF15963.5 EAU92771.2 - 5e-23 80.8 0.1 9.9e-23 79.8 0.1 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EAU92771.2 - 2e-10 40.7 0.1 1e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU92771.2 - 0.00022 21.4 0.1 0.00042 20.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RmlD_sub_bind PF04321.17 EAU92772.2 - 4.6e-10 39.1 0.0 2.9e-08 33.2 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EAU92772.2 - 9e-09 34.7 0.0 7.7e-06 25.1 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EAU92772.2 - 1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EAU92772.2 - 1.3e-07 31.4 0.0 3.9e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EAU92772.2 - 0.00027 21.2 0.0 0.00057 20.1 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EAU92772.2 - 0.0031 16.7 0.0 0.014 14.6 0.0 1.9 2 1 1 3 3 3 1 Male sterility protein Oxidored_FMN PF00724.20 EAU92773.2 - 2.8e-68 230.7 0.0 3.6e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EAU92773.2 - 0.044 12.9 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Fructosamin_kin PF03881.14 EAU92774.2 - 3e-60 203.9 0.0 3.5e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EAU92774.2 - 3.3e-12 46.9 0.0 4.6e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EAU92774.2 - 0.14 10.9 0.0 0.19 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) RNA_pol_Rpb2_6 PF00562.28 EAU92775.1 - 5.9e-125 417.4 0.1 9.1e-125 416.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EAU92775.1 - 1.3e-68 230.5 0.0 1.8e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EAU92775.1 - 7.5e-48 162.7 0.1 1.6e-47 161.6 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EAU92775.1 - 3.1e-32 110.8 0.1 8.9e-32 109.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EAU92775.1 - 2.7e-26 91.6 0.4 8.5e-26 90.0 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EAU92775.1 - 6.4e-26 90.3 0.1 1.7e-25 89.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EAU92775.1 - 7.2e-23 80.9 2.2 2.1e-22 79.4 2.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 EAU92775.1 - 0.65 10.7 2.5 0.65 10.8 0.8 1.9 2 0 0 2 2 2 0 MRN-interacting protein Lung_7-TM_R PF06814.13 EAU92776.2 - 6.3e-55 186.5 12.0 8.5e-55 186.1 12.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3099 PF11298.8 EAU92776.2 - 0.049 13.8 0.8 0.049 13.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) PepSY_TM PF03929.16 EAU92776.2 - 0.076 12.7 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 PepSY-associated TM region PX PF00787.24 EAU92777.1 - 2e-19 69.6 0.2 1.2e-18 67.2 0.3 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EAU92777.1 - 2.6e-08 33.7 2.8 0.0021 17.6 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EAU92777.1 - 0.00014 21.6 1.9 0.053 13.2 0.3 3.1 3 0 0 3 3 3 2 BAR domain BAR_3 PF16746.5 EAU92777.1 - 0.0068 16.1 0.6 0.37 10.4 0.0 2.7 2 1 1 3 3 3 1 BAR domain of APPL family PEP-utilisers_N PF05524.13 EAU92777.1 - 0.06 13.5 0.3 0.17 12.0 0.3 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Sec34 PF04136.15 EAU92777.1 - 0.078 12.8 2.5 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Sec34-like family NPV_P10 PF05531.12 EAU92777.1 - 0.49 10.9 1.6 8.7 6.9 0.2 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HORMA PF02301.18 EAU92778.2 - 3.4e-07 30.1 0.1 4.5e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 HORMA domain ABC1 PF03109.16 EAU92779.2 - 1.6e-21 76.7 0.0 2.7e-11 43.6 0.0 2.5 2 0 0 2 2 2 2 ABC1 family Glyco_transf_8 PF01501.20 EAU92780.1 - 7.4e-21 74.9 0.0 3e-20 72.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EAU92780.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Macoilin PF09726.9 EAU92781.2 - 6 5.3 7.1 6.3 5.2 7.1 1.0 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 EAU92781.2 - 7.1 7.3 13.8 0.8 10.3 6.7 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3759 PF12585.8 EAU92782.2 - 0.009 16.0 0.3 0.026 14.5 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) TrbL PF04610.14 EAU92782.2 - 0.1 12.3 1.3 0.21 11.3 1.3 1.5 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein UCMA PF17085.5 EAU92782.2 - 0.12 12.3 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Mating_C PF12737.7 EAU92783.1 - 5.6e-167 556.2 28.0 8.2e-167 555.6 28.0 1.2 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 Mating_N PF12731.7 EAU92783.1 - 1.8e-21 76.0 0.1 3.2e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox_KN PF05920.11 EAU92783.1 - 4.4e-15 55.3 3.8 1.7e-14 53.4 0.5 2.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EAU92783.1 - 0.002 17.9 0.0 0.0065 16.3 0.0 1.9 1 0 0 1 1 1 1 Homeodomain FlxA PF14282.6 EAU92783.1 - 0.81 9.7 3.6 0.54 10.3 0.4 2.3 2 0 0 2 2 2 0 FlxA-like protein Mating_C PF12737.7 EAU92786.2 - 4.6e-175 582.8 27.2 4.6e-175 582.8 27.2 1.7 2 0 0 2 2 2 1 C-terminal domain of homeodomain 1 Mating_N PF12731.7 EAU92786.2 - 1.2e-30 105.5 1.6 3.5e-30 104.0 1.6 1.8 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox_KN PF05920.11 EAU92786.2 - 1.9e-16 59.7 0.7 3e-15 55.8 0.0 3.1 3 0 0 3 3 3 1 Homeobox KN domain Homeodomain PF00046.29 EAU92786.2 - 0.00047 19.9 0.0 0.002 18.0 0.0 2.1 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 EAU92788.1 - 1.8e-12 46.9 1.6 1.8e-12 46.9 1.6 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EAU92788.1 - 0.00015 21.6 1.2 0.0004 20.2 1.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ail_Lom PF06316.11 EAU92788.1 - 0.21 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein VPS28 PF03997.12 EAU92788.1 - 2 8.1 3.4 4.7 6.8 2.2 1.9 1 1 1 2 2 2 0 VPS28 protein Mating_C PF12737.7 EAU92789.1 - 1.6e-165 551.4 33.6 1.6e-165 551.4 33.6 1.7 2 0 0 2 2 2 1 C-terminal domain of homeodomain 1 Mating_N PF12731.7 EAU92789.1 - 1.2e-27 95.8 2.6 2.6e-27 94.7 2.6 1.6 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox_KN PF05920.11 EAU92789.1 - 1.5e-13 50.4 0.7 1.5e-13 50.4 0.7 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EAU92789.1 - 0.0036 17.1 0.1 0.0036 17.1 0.1 2.9 3 0 0 3 3 3 1 Homeodomain Peptidase_M3 PF01432.20 EAU92790.2 - 9.2e-137 457.0 0.0 1.3e-136 456.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 EAU92790.2 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Effector protein APG6_N PF17675.1 EAU92791.1 - 0.05 14.1 1.1 0.093 13.3 1.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1754 PF08555.10 EAU92792.1 - 3.4e-16 59.8 9.1 3.4e-16 59.8 9.1 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.6 EAU92792.1 - 0.025 13.9 0.1 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FAM60A PF15396.6 EAU92792.1 - 0.047 13.7 6.7 0.056 13.4 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A UPF0172 PF03665.13 EAU92792.1 - 0.049 13.7 1.9 0.065 13.3 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) PP2C_C PF07830.13 EAU92792.1 - 0.79 10.2 6.0 1.1 9.7 0.1 2.6 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1751 PF08551.10 EAU92793.2 - 3.1e-21 75.8 5.0 5.3e-21 75.0 5.0 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EAU92793.2 - 0.1 12.6 10.7 0.49 10.4 10.7 2.0 1 1 0 1 1 1 0 Rhomboid family Vps51 PF08700.11 EAU92794.2 - 5.1e-12 45.7 0.5 5.1e-12 45.7 0.5 2.4 3 0 0 3 3 3 1 Vps51/Vps67 HEPN_Apea PF18739.1 EAU92794.2 - 0.072 13.5 0.4 5 7.6 0.0 2.7 2 0 0 2 2 2 0 Apea-like HEPN Sdh_cyt PF01127.22 EAU92795.2 - 0.18 11.8 5.2 0.033 14.2 1.2 1.9 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2568 PF10823.8 EAU92795.2 - 0.63 10.4 6.2 0.44 10.8 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2568) 2TM PF13239.6 EAU92795.2 - 5.5 7.4 0.0 5.5 7.4 0.0 3.3 3 1 0 3 3 3 0 2TM domain SecE PF00584.20 EAU92796.1 - 2.9e-17 62.3 0.1 3.3e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Mit_proteolip PF08039.11 EAU92796.1 - 0.17 12.3 0.0 0.23 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial proteolipid PPR_2 PF13041.6 EAU92797.2 - 6.4e-06 26.3 0.1 0.14 12.4 0.0 4.9 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.20 EAU92797.2 - 6.9e-06 26.0 0.1 0.43 10.9 0.0 6.2 8 0 0 8 8 8 1 PPR repeat PPR_1 PF12854.7 EAU92797.2 - 0.00034 20.3 0.1 0.019 14.7 0.1 3.0 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 EAU92797.2 - 0.00056 19.3 0.2 0.46 9.8 0.0 3.2 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP GDC-P PF02347.16 EAU92798.1 - 8.7e-184 611.3 0.0 6.4e-173 575.5 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EAU92798.1 - 0.00012 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EAU92798.1 - 0.00023 20.2 0.1 0.0013 17.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V YccV-like PF08755.11 EAU92800.2 - 1e-21 77.3 0.0 3.2e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EAU92800.2 - 3e-05 23.6 0.0 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.7 EAU92800.2 - 0.005 16.7 1.5 0.017 15.0 1.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU92800.2 - 0.086 12.7 0.4 0.27 11.2 0.4 1.9 1 0 0 1 1 1 0 F-box domain Nop52 PF05997.12 EAU92801.1 - 1.4e-79 266.9 0.1 1.9e-79 266.4 0.1 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 EAU92801.1 - 0.0011 18.6 0.0 0.0062 16.1 0.0 1.9 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II TAN PF11640.8 EAU92801.1 - 0.0053 16.9 0.2 0.053 13.6 0.0 2.5 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair UQ_con PF00179.26 EAU92802.1 - 4.1e-40 136.7 0.1 5.3e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EAU92802.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain 2OG-FeII_Oxy PF03171.20 EAU92803.2 - 0.0003 21.2 0.0 0.00056 20.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EAU92803.2 - 0.0014 19.4 0.1 0.0058 17.4 0.1 2.2 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Chorismate_bind PF00425.18 EAU92804.1 - 5e-69 232.7 0.0 6.6e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EAU92804.1 - 1.7e-33 116.0 0.0 2.5e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EAU92804.1 - 1.8e-15 57.4 0.0 4.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EAU92804.1 - 5.4e-06 26.3 1.4 1.2e-05 25.2 1.4 1.5 1 1 0 1 1 1 1 Peptidase C26 MMS19_N PF14500.6 EAU92805.1 - 0.032 13.8 4.4 0.78 9.3 0.0 3.6 4 1 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II dCMP_cyt_deam_1 PF00383.23 EAU92806.2 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EAU92806.2 - 0.0085 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_14 PF13173.6 EAU92806.2 - 0.1 12.6 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain 2-oxogl_dehyd_N PF16078.5 EAU92806.2 - 0.23 11.1 0.5 0.61 9.7 0.0 2.0 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus RNase_P_pop3 PF08228.11 EAU92807.2 - 2.1e-16 60.4 0.0 2.2e-11 44.1 0.0 2.4 2 1 0 2 2 2 2 RNase P subunit Pop3 Vta1 PF04652.16 EAU92808.2 - 3.6e-46 156.8 0.1 6e-46 156.0 0.1 1.4 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 EAU92808.2 - 2.1e-16 59.3 1.4 2.1e-16 59.3 1.4 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain Lipase_GDSL_2 PF13472.6 EAU92810.2 - 6.2e-13 49.5 0.6 7.9e-13 49.2 0.6 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EAU92810.2 - 0.00035 20.6 0.0 0.0007 19.6 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MMR_HSR1 PF01926.23 EAU92811.2 - 9.8e-16 57.9 0.0 6.9e-15 55.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU92811.2 - 2.6e-07 30.3 0.0 8e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAU92811.2 - 5.5e-05 23.1 0.1 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EAU92811.2 - 0.002 18.2 1.6 0.035 14.2 0.1 3.3 3 1 1 4 4 4 1 Dynamin family AAA_16 PF13191.6 EAU92811.2 - 0.0057 17.1 0.1 2.4 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain PduV-EutP PF10662.9 EAU92811.2 - 0.017 14.9 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EAU92811.2 - 0.03 14.6 0.0 0.65 10.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EAU92811.2 - 0.091 12.1 0.0 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 AIG1 family SDA1 PF05285.12 EAU92811.2 - 1.1 8.6 6.9 2.5 7.4 6.9 1.6 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 EAU92813.1 - 4.6e-16 58.9 7.2 0.039 14.8 0.0 7.3 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU92813.1 - 2.8e-08 33.9 0.1 0.45 10.9 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EAU92813.1 - 0.011 15.6 0.1 0.89 9.6 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PsiB PF06290.11 EAU92813.1 - 0.06 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) F-box-like PF12937.7 EAU92814.1 - 8.6e-10 38.4 1.6 3e-08 33.4 0.5 2.5 2 0 0 2 2 2 2 F-box-like LRR_4 PF12799.7 EAU92814.1 - 0.083 13.3 1.5 0.38 11.2 0.5 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) PB1 PF00564.24 EAU92815.2 - 4.5e-13 48.9 0.0 1.1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain TAF1D PF15333.6 EAU92815.2 - 0.046 13.4 0.7 0.092 12.5 0.7 1.4 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF4337 PF14235.6 EAU92815.2 - 0.9 9.6 3.1 2.2 8.4 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ApbA_C PF08546.11 EAU92816.1 - 1.4e-34 119.0 0.1 2.2e-34 118.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EAU92816.1 - 1.2e-21 77.0 0.0 7.9e-21 74.3 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA O-FucT PF10250.9 EAU92817.2 - 6.9e-07 29.3 0.0 1.9e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TPT PF03151.16 EAU92818.1 - 1e-10 41.5 21.2 1.3e-10 41.1 21.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EAU92818.1 - 1.1e-07 32.1 33.0 1.6e-05 25.0 14.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family RabGAP-TBC PF00566.18 EAU92821.2 - 1.4e-25 90.3 0.0 4.3e-25 88.7 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain GCP_C_terminal PF04130.13 EAU92822.2 - 2.6e-33 115.8 0.0 5.1e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EAU92822.2 - 1.3e-23 84.1 0.5 1.1e-21 77.8 0.2 2.6 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal Pyrophosphatase PF00719.19 EAU92823.1 - 2.3e-60 203.0 0.2 2.9e-60 202.7 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase ANAPC15 PF15243.6 EAU92824.2 - 0.028 14.8 3.3 0.059 13.8 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 I-set PF07679.16 EAU92824.2 - 0.1 12.7 0.0 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin I-set domain dsrm PF00035.26 EAU92825.2 - 4.1e-09 37.0 0.0 1e-08 35.7 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EAU92825.2 - 0.036 14.2 0.0 0.18 12.0 0.0 1.9 1 1 0 1 1 1 0 Ribonuclease-III-like Thioredoxin PF00085.20 EAU92826.2 - 5.2e-19 68.1 0.0 1.9e-17 63.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 EAU92826.2 - 4.6e-05 22.9 0.0 5.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EAU92826.2 - 0.00085 19.7 0.1 0.0026 18.2 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EAU92826.2 - 0.1 13.0 0.1 6 7.3 0.0 2.7 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EAU92826.2 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Glyco_transf_22 PF03901.17 EAU92828.2 - 4.2e-77 260.1 12.1 7.8e-77 259.3 12.1 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family SpoIISA_toxin PF14171.6 EAU92828.2 - 0.19 11.4 1.3 0.41 10.3 0.3 1.9 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system FtsX PF02687.21 EAU92829.1 - 3.7 8.1 7.6 1.1 9.8 0.1 2.7 1 1 1 2 2 2 0 FtsX-like permease family F-box PF00646.33 EAU92830.1 - 9.3e-05 22.2 0.1 0.0002 21.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU92830.1 - 0.0013 18.5 0.4 0.0033 17.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like adh_short_C2 PF13561.6 EAU92831.1 - 5.8e-52 176.6 0.3 7.1e-52 176.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU92831.1 - 2.1e-44 151.3 0.7 2.6e-44 151.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU92831.1 - 9.1e-11 42.0 0.2 1.2e-10 41.6 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EAU92831.1 - 0.005 16.3 0.0 0.0082 15.5 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EAU92831.1 - 0.021 14.3 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WASH-7_N PF14745.6 EAU92831.1 - 0.046 12.2 0.1 0.061 11.8 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal RibD_C PF01872.17 EAU92832.1 - 7.2e-34 117.4 0.0 9e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain BTB PF00651.31 EAU92834.1 - 0.015 15.6 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Smac_DIABLO PF09057.10 EAU92834.1 - 0.15 11.4 0.1 0.31 10.4 0.1 1.5 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Peptidase_M22 PF00814.25 EAU92835.2 - 3.3e-82 276.2 0.0 3.9e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EAU92835.2 - 0.014 15.0 0.0 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus LIAS_N PF16881.5 EAU92837.1 - 6.4e-34 116.6 0.0 1.3e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EAU92837.1 - 2.4e-15 57.3 0.0 6e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Cmc1 PF08583.10 EAU92838.2 - 7.8e-13 48.2 1.2 9.4e-13 48.0 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 EAU92838.2 - 0.077 13.4 2.1 6.2 7.3 0.1 2.1 1 1 2 3 3 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EAU92838.2 - 0.16 12.1 3.0 10 6.4 0.4 2.2 2 0 0 2 2 2 0 CHCH domain PEX11 PF05648.14 EAU92839.1 - 1.1e-54 185.3 0.7 1.2e-54 185.1 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Lyase_1 PF00206.20 EAU92840.2 - 2.2e-120 401.8 0.0 2.8e-120 401.4 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EAU92840.2 - 1.2e-19 70.5 0.0 2.6e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EAU92840.2 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain SNF2_N PF00176.23 EAU92841.2 - 3e-66 223.6 1.2 5e-66 222.8 1.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EAU92841.2 - 3.7e-48 163.3 19.2 1.2e-47 161.6 19.2 2.0 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.31 EAU92841.2 - 1.1e-15 58.0 0.0 3.3e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU92841.2 - 1.1e-06 28.7 0.0 3.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EAU92841.2 - 2e-05 23.9 0.0 0.00035 19.8 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 HSA PF07529.13 EAU92841.2 - 0.005 17.1 9.6 0.037 14.4 9.6 2.6 1 0 0 1 1 1 1 HSA DKCLD PF08068.12 EAU92842.1 - 5e-33 112.9 0.1 4.7e-32 109.8 0.2 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EAU92842.1 - 3.5e-24 84.7 0.8 7.7e-24 83.6 0.8 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EAU92842.1 - 7.3e-21 73.9 1.2 7.3e-21 73.9 1.2 1.8 2 0 0 2 2 2 1 PUA domain TruB_N PF01509.18 EAU92842.1 - 1.6e-20 74.0 8.9 3.6e-16 59.9 0.1 3.8 2 1 1 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) CDC27 PF09507.10 EAU92842.1 - 0.00031 20.3 27.5 0.00041 19.9 27.5 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 UPF0113 PF03657.13 EAU92842.1 - 0.011 16.0 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain Red1 PF07964.11 EAU92842.1 - 7.5 4.7 23.2 9.8 4.3 23.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Ribosomal_L22e PF01776.17 EAU92843.2 - 2.2e-47 159.9 0.5 2.7e-47 159.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 EAU92843.2 - 0.042 12.6 0.1 0.048 12.5 0.1 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) HA2 PF04408.23 EAU92844.2 - 1.6e-16 60.5 0.0 4.1e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAU92844.2 - 6.7e-14 52.2 0.0 1.6e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EAU92844.2 - 2.8e-09 37.2 0.0 5.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EAU92844.2 - 4.5e-08 33.1 0.0 8.2e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU92844.2 - 1.1e-05 25.7 0.0 3.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAU92844.2 - 0.026 15.1 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 EAU92844.2 - 0.13 11.6 0.0 2.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.6 EAU92844.2 - 0.77 10.2 3.7 1.4 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 EAU92846.2 - 1.5e-64 217.9 0.0 1.8e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92846.2 - 3e-26 92.3 0.0 5.9e-26 91.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU92846.2 - 3.9e-05 23.1 0.0 5.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EAU92846.2 - 0.041 12.8 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EAU92846.2 - 0.054 13.4 0.3 0.14 12.0 0.4 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EAU92846.2 - 0.063 12.6 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EAU92846.2 - 0.095 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Fez1 PF06818.15 EAU92847.2 - 0.0024 18.4 2.0 0.0024 18.4 2.0 1.5 2 0 0 2 2 1 1 Fez1 Phage_GP20 PF06810.11 EAU92847.2 - 0.026 14.3 4.0 0.051 13.4 4.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4515 PF14988.6 EAU92847.2 - 0.038 13.8 6.9 0.066 13.0 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) MAD PF05557.13 EAU92847.2 - 0.049 12.0 9.3 0.074 11.4 9.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein GAS PF13851.6 EAU92847.2 - 0.052 12.9 9.9 0.09 12.1 9.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 EAU92847.2 - 0.072 11.7 3.7 0.13 10.9 3.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A SAP PF02037.27 EAU92847.2 - 0.17 11.7 1.2 0.48 10.2 0.4 2.3 2 0 0 2 2 2 0 SAP domain NPV_P10 PF05531.12 EAU92847.2 - 0.3 11.6 1.8 16 6.1 0.6 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EAU92847.2 - 0.36 11.1 5.9 1.1 9.6 4.1 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cauli_AT PF03233.13 EAU92847.2 - 0.45 10.4 2.0 0.6 10.0 1.0 1.6 2 0 0 2 2 1 0 Aphid transmission protein Spc7 PF08317.11 EAU92847.2 - 0.82 8.5 10.4 1.4 7.7 10.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 EAU92847.2 - 0.89 10.0 5.7 2.5 8.5 5.7 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) AAA_23 PF13476.6 EAU92847.2 - 1 9.8 6.7 2.2 8.7 6.7 1.5 1 0 0 1 1 1 0 AAA domain PRKG1_interact PF15898.5 EAU92847.2 - 1.1 10.2 13.2 0.07 14.0 7.5 1.9 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 EAU92847.2 - 1.7 8.5 11.0 4.1 7.2 4.8 2.4 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 EAU92847.2 - 1.7 9.3 5.3 4.4 8.0 5.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Sec34 PF04136.15 EAU92847.2 - 2 8.3 4.8 7.1 6.5 1.0 1.8 1 1 1 2 2 2 0 Sec34-like family DUF2730 PF10805.8 EAU92847.2 - 3.1 8.0 4.8 25 5.0 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) MPS2 PF17060.5 EAU92847.2 - 5.6 6.1 9.9 0.33 10.2 4.2 1.7 2 0 0 2 2 2 0 Monopolar spindle protein 2 FlaC_arch PF05377.11 EAU92847.2 - 7.7 7.0 6.7 36 4.9 0.2 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) PKcGMP_CC PF16808.5 EAU92847.2 - 9.2 6.2 15.3 3.8 7.4 2.7 3.4 2 1 2 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase OmpH PF03938.14 EAU92847.2 - 10 6.5 7.6 20 5.5 7.6 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FMN_dh PF01070.18 EAU92848.2 - 6.3e-108 360.9 0.1 7.8e-108 360.6 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EAU92848.2 - 1.4e-21 76.4 0.0 3e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EAU92848.2 - 5.6e-07 29.0 0.0 9.2e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EAU92848.2 - 7.9e-05 21.8 1.5 0.00071 18.7 0.2 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EAU92848.2 - 0.00015 21.3 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 EAU92848.2 - 0.046 13.0 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG LIM PF00412.22 EAU92849.2 - 4.7e-11 42.7 32.4 1.4e-06 28.4 6.1 4.8 5 0 0 5 5 5 3 LIM domain C2-set_2 PF08205.12 EAU92849.2 - 0.11 12.5 2.3 14 5.9 0.2 2.9 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain DUF3938 PF13074.6 EAU92850.2 - 1.3 9.3 4.8 0.21 11.9 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) DnaJ PF00226.31 EAU92851.1 - 3.6e-22 78.3 2.6 6.8e-22 77.4 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.9 EAU92851.1 - 0.077 13.1 3.9 0.14 12.3 3.9 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 EAU92851.1 - 0.12 12.4 3.2 0.29 11.2 3.2 1.7 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 EAU92851.1 - 0.18 11.6 2.6 0.41 10.4 2.6 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper Sin_N PF04801.13 EAU92854.1 - 1.7e-26 93.4 0.0 2.2e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region AAA_18 PF13238.6 EAU92856.1 - 8.4e-26 91.0 0.0 9.7e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EAU92856.1 - 5.5e-07 30.1 0.0 1.2e-06 29.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EAU92856.1 - 7e-06 26.5 0.0 9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EAU92856.1 - 1.8e-05 24.9 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU92856.1 - 5.8e-05 23.4 0.0 7.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EAU92856.1 - 8.8e-05 22.8 0.0 0.00012 22.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 EAU92856.1 - 0.001 19.0 0.0 0.26 11.1 0.0 2.1 1 1 1 2 2 2 1 Deoxynucleoside kinase ADK PF00406.22 EAU92856.1 - 0.0017 18.5 0.0 0.0043 17.1 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.10 EAU92856.1 - 0.0041 16.6 0.0 0.0044 16.5 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_14 PF13173.6 EAU92856.1 - 0.0061 16.6 0.0 0.0074 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EAU92856.1 - 0.0062 17.1 0.0 0.007 16.9 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EAU92856.1 - 0.019 14.9 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 EAU92856.1 - 0.021 15.2 0.1 0.021 15.2 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EAU92856.1 - 0.023 15.1 0.0 0.029 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase RuvB_N PF05496.12 EAU92856.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EAU92856.1 - 0.029 14.1 0.1 0.036 13.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EAU92856.1 - 0.039 13.7 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EAU92856.1 - 0.051 13.5 0.3 0.095 12.6 0.3 1.5 1 1 0 1 1 1 0 NTPase DUF2075 PF09848.9 EAU92856.1 - 0.057 12.6 0.0 0.059 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.26 EAU92856.1 - 0.061 13.0 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Thymidylate_kin PF02223.17 EAU92856.1 - 0.07 12.8 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase CPT PF07931.12 EAU92856.1 - 0.072 12.9 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MeaB PF03308.16 EAU92856.1 - 0.074 12.0 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EAU92856.1 - 0.078 12.7 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EAU92856.1 - 0.083 12.6 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EAU92856.1 - 0.091 12.9 0.0 0.14 12.2 0.0 1.5 2 0 0 2 2 1 0 Sigma-54 interaction domain ATPase PF06745.13 EAU92856.1 - 0.11 11.9 0.4 0.14 11.5 0.4 1.3 1 1 0 1 1 1 0 KaiC AAA_25 PF13481.6 EAU92856.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EAU92856.1 - 0.14 11.4 0.1 0.21 10.9 0.1 1.3 1 1 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EAU92856.1 - 0.16 12.0 0.1 0.2 11.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EAU92856.1 - 0.82 10.0 3.8 0.33 11.3 1.1 1.7 1 1 1 2 2 2 0 AAA domain Cyclin_C_2 PF16899.5 EAU92858.1 - 6.8e-12 45.7 2.5 3.8e-09 36.9 0.2 2.8 2 1 1 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EAU92858.1 - 3.9e-10 39.6 0.4 7.9e-10 38.6 0.4 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain FCH PF00611.23 EAU92859.1 - 1.9e-07 31.2 0.2 2.6e-07 30.8 0.2 1.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain HigB-like_toxin PF05015.13 EAU92859.1 - 0.021 15.2 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 RelE-like toxin of type II toxin-antitoxin system HigB Imm43 PF15570.6 EAU92859.1 - 0.055 13.5 0.4 0.075 13.0 0.4 1.1 1 0 0 1 1 1 0 Immunity protein 43 MSC PF09402.10 EAU92859.1 - 0.33 10.3 1.3 2.1 7.7 1.3 1.9 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain RhoGAP PF00620.27 EAU92860.2 - 4.8e-42 143.4 0.0 9.4e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF1764 PF08576.10 EAU92861.2 - 6.2e-09 36.7 20.4 1.2e-07 32.6 8.9 2.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Ndc1_Nup PF09531.10 EAU92861.2 - 0.27 9.9 2.6 0.33 9.6 2.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup C_Hendra PF16821.5 EAU92861.2 - 0.78 9.6 3.9 1.3 8.8 3.9 1.3 1 0 0 1 1 1 0 C protein from hendra and measles viruses Presenilin PF01080.17 EAU92861.2 - 0.99 8.1 4.6 1.4 7.6 4.6 1.1 1 0 0 1 1 1 0 Presenilin NST1 PF13945.6 EAU92861.2 - 1.9 8.5 11.6 2.8 8.0 11.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator SRP-alpha_N PF04086.13 EAU92861.2 - 7 6.5 18.3 9.7 6.0 18.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal ARID PF01388.21 EAU92862.2 - 5.9e-17 62.1 0.0 1.7e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 EAU92862.2 - 0.11 11.8 0.5 0.71 9.1 0.0 2.3 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa Arrestin_C PF02752.22 EAU92863.1 - 9.2e-06 26.2 0.0 2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Ras PF00071.22 EAU92864.1 - 4.9e-55 185.5 0.0 6.1e-55 185.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU92864.1 - 7.2e-34 116.6 0.0 1.1e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU92864.1 - 1.5e-14 53.8 0.0 9e-14 51.3 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAU92864.1 - 1.5e-06 27.7 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAU92864.1 - 2.5e-05 23.9 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EAU92864.1 - 0.00012 22.2 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EAU92864.1 - 0.00039 20.8 0.5 0.00093 19.6 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain MRI PF15325.6 EAU92864.1 - 0.039 15.0 2.1 0.089 13.9 2.1 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection RsgA_GTPase PF03193.16 EAU92864.1 - 0.1 12.5 0.1 14 5.6 0.0 2.9 2 1 1 3 3 3 0 RsgA GTPase Rad21_Rec8_N PF04825.13 EAU92865.2 - 2.6e-22 79.1 0.1 5.7e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Peptidase_M28 PF04389.17 EAU92866.1 - 7.7e-30 104.1 0.0 1.6e-29 103.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EAU92866.1 - 1.2e-08 34.9 0.0 2.1e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EAU92866.1 - 0.0041 16.2 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Alginate_lyase PF05426.12 EAU92867.2 - 6.6e-42 143.9 0.0 1.1e-41 143.2 0.0 1.2 1 0 0 1 1 1 1 Alginate lyase AMP-binding PF00501.28 EAU92868.2 - 9.7e-68 228.7 0.0 1.2e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU92868.2 - 9.4e-20 71.4 0.1 5.1e-19 69.0 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GYF PF02213.16 EAU92869.2 - 3.1e-17 62.0 0.1 6.1e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EAU92869.2 - 0.0078 16.0 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 GYF domain 2 DegQ PF08181.11 EAU92869.2 - 0.098 12.8 0.3 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 DegQ (SacQ) family FAD-oxidase_C PF02913.19 EAU92870.2 - 1.6e-56 191.8 0.1 2.3e-56 191.2 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EAU92870.2 - 1.3e-17 63.8 0.1 4.7e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Methyltransf_14 PF08484.11 EAU92870.2 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain BRCT_2 PF16589.5 EAU92871.2 - 2.7e-12 46.9 0.0 6.5e-08 32.9 0.0 2.4 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EAU92871.2 - 2.7e-10 40.3 1.6 6.8e-10 39.0 1.6 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 EAU92871.2 - 0.057 14.0 3.7 1.8 9.2 2.5 3.1 2 1 1 3 3 3 0 Rap1, DNA-binding Pkinase PF00069.25 EAU92872.2 - 6.8e-62 209.2 0.0 1.9e-61 207.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92872.2 - 8.2e-20 71.2 0.0 1.1e-18 67.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU92872.2 - 0.00016 21.1 0.1 0.026 13.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like DUF3717 PF12512.8 EAU92872.2 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) APH PF01636.23 EAU92872.2 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EAU92872.2 - 0.23 10.3 0.1 0.54 9.1 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Dmrt1 PF12374.8 EAU92872.2 - 0.32 11.5 0.1 0.32 11.5 0.1 2.7 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 TTL PF03133.15 EAU92873.1 - 3.1e-45 154.5 0.0 4.6e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family RhoGAP PF00620.27 EAU92873.1 - 0.05 13.4 0.2 0.22 11.3 0.1 1.9 1 1 1 2 2 2 0 RhoGAP domain DUF3848 PF12959.7 EAU92873.1 - 0.15 12.2 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) MMM1 PF10296.9 EAU92874.1 - 1.4e-40 139.3 0.0 8.2e-30 104.0 0.0 3.1 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 RNA_pol_Rpb8 PF03870.15 EAU92876.1 - 1.1e-48 164.9 0.1 1.3e-48 164.8 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Sec7 PF01369.20 EAU92878.2 - 8.4e-31 107.1 0.1 1.3e-30 106.4 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EAU92878.2 - 1e-11 45.3 0.0 2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EAU92878.2 - 8.5e-11 42.3 0.0 1.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF3439 PF11921.8 EAU92878.2 - 6.9 6.7 11.3 22 5.0 11.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pescadillo_N PF06732.11 EAU92879.1 - 7.1e-123 409.5 0.0 7.1e-123 409.5 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EAU92879.1 - 2.9e-08 34.0 0.0 7.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EAU92879.1 - 4.5e-05 23.8 0.0 9.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EAU92879.1 - 0.012 15.9 0.2 0.06 13.6 0.0 2.2 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Peptidase_A3 PF02160.15 EAU92879.1 - 0.73 9.3 3.0 1.7 8.0 3.0 1.6 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) LSM PF01423.22 EAU92880.1 - 7.6e-16 57.6 0.2 1.5e-15 56.6 0.2 1.5 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 EAU92880.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Hfq protein RdRP PF05183.12 EAU92881.1 - 1.4e-173 578.8 0.0 1.7e-173 578.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Cyclin_N PF00134.23 EAU92883.1 - 1.2e-39 134.9 1.9 2.7e-39 133.8 0.4 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EAU92883.1 - 1.9e-10 40.9 0.1 4.2e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4838 PF16126.5 EAU92883.1 - 0.054 12.9 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) GFO_IDH_MocA PF01408.22 EAU92884.2 - 3.9e-13 50.3 0.5 2.8e-12 47.5 0.5 2.4 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 EAU92884.2 - 0.022 15.3 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain GFO_IDH_MocA_C PF02894.17 EAU92884.2 - 0.022 14.8 0.0 0.058 13.4 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EAU92884.2 - 0.031 14.9 0.0 0.05 14.2 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Hydrolase PF00702.26 EAU92884.2 - 0.04 14.2 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sacchrp_dh_NADP PF03435.18 EAU92884.2 - 0.05 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain WAC_Acf1_DNA_bd PF10537.9 EAU92885.2 - 2.5e-35 121.0 0.5 2.5e-35 121.0 0.5 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EAU92885.2 - 7.8e-33 112.9 0.1 7.8e-33 112.9 0.1 2.8 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EAU92885.2 - 1.4e-14 54.2 0.9 3.4e-14 52.9 0.5 1.8 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 EAU92885.2 - 1.4e-07 30.9 0.0 3.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDHD PF02862.17 EAU92885.2 - 0.047 13.8 1.6 2.5 8.2 0.1 2.3 2 0 0 2 2 2 0 DDHD domain DUF4325 PF14213.6 EAU92885.2 - 0.1 12.3 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) Aa_trans PF01490.18 EAU92886.2 - 1.2e-48 165.8 11.1 1.6e-48 165.5 11.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EAU92886.2 - 2.2e-06 27.0 9.8 3.2e-06 26.5 9.8 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family CSN8_PSD8_EIF3K PF10075.9 EAU92887.1 - 2.7e-23 82.5 0.0 4.7e-23 81.8 0.0 1.4 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family WD40 PF00400.32 EAU92888.2 - 2.8e-61 202.0 16.6 2.3e-10 40.9 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU92888.2 - 1.7e-27 95.5 0.3 3.1e-05 24.2 0.0 6.2 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EAU92888.2 - 2e-11 43.8 0.0 0.00012 21.5 0.0 3.2 2 1 1 3 3 3 3 WD40-like domain eIF2A PF08662.11 EAU92888.2 - 3e-10 40.3 0.0 0.00017 21.5 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EAU92888.2 - 7.5e-09 34.8 0.8 0.14 10.8 0.1 4.2 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EAU92888.2 - 9.8e-07 28.0 2.3 0.28 10.1 1.1 4.2 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EAU92888.2 - 0.00033 19.8 0.0 0.44 9.5 0.0 3.0 1 1 1 3 3 3 1 Coatomer WD associated region PALB2_WD40 PF16756.5 EAU92888.2 - 0.0076 15.2 0.8 1.6 7.6 0.3 3.2 1 1 2 3 3 3 1 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 EAU92888.2 - 0.0093 16.4 0.3 2.6 8.6 0.0 3.4 2 1 1 3 3 3 1 PQQ-like domain Frtz PF11768.8 EAU92888.2 - 0.017 13.5 0.0 0.52 8.6 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 EAU92888.2 - 0.02 12.9 0.0 0.071 11.1 0.0 1.8 2 0 0 2 2 2 0 IKI3 family Hira PF07569.11 EAU92888.2 - 0.028 14.2 0.1 4 7.1 0.0 2.7 2 0 0 2 2 2 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EAU92888.2 - 0.035 12.8 2.7 2.3 6.9 0.1 3.7 3 2 1 4 4 4 0 Nup133 N terminal like RAB3GAP2_N PF14655.6 EAU92888.2 - 0.036 13.3 0.0 18 4.4 0.0 3.3 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ubiquitin PF00240.23 EAU92889.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EAU92889.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EAU92889.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EAU92889.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EAU92889.1 - 1.4e-14 54.2 7.5 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EAU92889.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EAU92889.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EAU92889.1 - 5.3e-10 39.4 0.4 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EAU92889.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EAU92889.1 - 5.1e-07 29.3 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EAU92889.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 EAU92889.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 EAU92889.1 - 5.6e-06 26.7 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EAU92889.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 EAU92889.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 EAU92889.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EAU92889.1 - 0.00034 20.1 0.0 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 EAU92889.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 EAU92889.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 EAU92889.1 - 0.007 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EAU92889.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 EAU92889.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 EAU92889.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif DMA PF03474.14 EAU92889.1 - 0.28 10.8 4.0 1e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 DMRTA motif Phage_sheath_1N PF17481.2 EAU92889.1 - 0.44 11.0 9.2 46 4.6 1.3 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 EAU92889.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 EAU92889.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 EAU92889.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein Fcf1 PF04900.12 EAU92890.2 - 5.9e-32 110.0 0.4 9.5e-32 109.3 0.4 1.3 1 0 0 1 1 1 1 Fcf1 PGA2 PF07543.12 EAU92890.2 - 2.6 8.0 9.0 4.4 7.3 9.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 SRP-alpha_N PF04086.13 EAU92890.2 - 5.3 6.9 16.1 7.3 6.4 16.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SWIRM-assoc_2 PF16496.5 EAU92890.2 - 6.3 5.6 13.1 9.9 4.9 13.1 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF2012 PF09430.10 EAU92891.1 - 4.6e-23 81.7 0.0 6.5e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) fn3_3 PF14686.6 EAU92891.1 - 0.00035 20.3 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EAU92891.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain SOP4 PF17081.5 EAU92891.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein CarbopepD_reg_2 PF13715.6 EAU92891.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 CarboxypepD_reg-like domain CAP PF00188.26 EAU92893.1 - 3.2e-19 70.0 0.0 4.9e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SUR7 PF06687.12 EAU92894.2 - 0.043 13.5 1.2 0.055 13.1 1.2 1.2 1 0 0 1 1 1 0 SUR7/PalI family Colicin_V PF02674.16 EAU92894.2 - 0.2 11.6 3.3 0.28 11.2 3.3 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF4231 PF14015.6 EAU92894.2 - 0.35 11.4 2.7 0.73 10.3 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) CD34_antigen PF06365.12 EAU92894.2 - 2.4 7.7 4.0 1 8.9 0.2 1.9 1 1 1 2 2 2 0 CD34/Podocalyxin family FAD_binding_6 PF00970.24 EAU92895.1 - 4.3e-33 113.6 0.0 6.7e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EAU92895.1 - 1.1e-27 96.8 0.0 1.7e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EAU92895.1 - 2.7e-05 24.4 0.0 0.00098 19.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EAU92895.1 - 0.0011 19.2 0.0 0.0048 17.1 0.0 2.0 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DSPc PF00782.20 EAU92896.1 - 7.4e-20 71.1 0.0 7e-18 64.7 0.0 3.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EAU92896.1 - 0.00062 19.4 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BUD22 PF09073.10 EAU92896.1 - 2.7 7.3 12.2 4.4 6.6 12.2 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 EAU92896.1 - 6.2 5.3 18.3 0.035 12.7 8.5 1.8 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF846 PF05832.12 EAU92897.2 - 1.2e-54 184.2 8.8 1.4e-54 183.9 8.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2207 PF09972.9 EAU92897.2 - 0.23 10.2 1.5 10 4.8 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Caveolin PF01146.17 EAU92898.2 - 3.9 7.5 5.6 8.5 6.3 0.7 2.5 2 0 0 2 2 2 0 Caveolin Pkinase PF00069.25 EAU92900.2 - 0.22 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain AA_permease PF00324.21 EAU92901.2 - 2e-126 422.4 30.0 2.4e-126 422.1 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EAU92901.2 - 9.6e-38 130.1 35.6 1.2e-37 129.8 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.20 EAU92902.2 - 3.4e-41 141.5 0.0 5.5e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 EAU92902.2 - 1.1e-09 37.9 2.3 0.00061 19.5 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EAU92902.2 - 0.00031 21.1 6.0 0.036 14.5 0.3 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EAU92902.2 - 0.066 13.8 4.1 15 6.7 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat PAXNEB PF05625.11 EAU92903.2 - 5.3e-51 173.9 0.0 7.9e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Peptidase_S26 PF10502.9 EAU92904.2 - 1.9e-06 27.7 0.0 0.00082 19.2 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EAU92904.2 - 2.3e-06 27.5 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like TPR_2 PF07719.17 EAU92905.2 - 0.00019 21.3 2.1 0.87 9.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU92905.2 - 0.0042 16.9 1.5 0.78 9.7 0.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU92905.2 - 0.012 16.4 2.2 0.11 13.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NPA PF16469.5 EAU92905.2 - 0.012 16.2 5.1 0.022 15.4 5.1 1.4 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 TPR_7 PF13176.6 EAU92905.2 - 0.021 14.8 0.1 2.2 8.5 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2400 PF09674.10 EAU92905.2 - 0.025 14.6 0.3 0.034 14.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) TPR_11 PF13414.6 EAU92905.2 - 0.042 13.5 0.2 3 7.6 0.0 2.4 2 0 0 2 2 2 0 TPR repeat PCRF PF03462.18 EAU92905.2 - 0.22 11.4 5.1 0.16 11.8 3.5 1.5 2 0 0 2 2 2 0 PCRF domain MCU PF04678.13 EAU92905.2 - 3.7 7.6 6.6 0.41 10.7 0.9 2.0 1 1 1 2 2 2 0 Mitochondrial calcium uniporter AlaDh_PNT_N PF05222.15 EAU92906.1 - 8.4e-30 103.8 0.0 1.2e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EAU92906.1 - 0.0061 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF5060 PF16586.5 EAU92906.1 - 0.053 13.9 0.0 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) Acyltransferase PF01553.21 EAU92909.2 - 9.6e-16 57.6 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EAU92909.2 - 1.6e-07 31.3 0.5 8.4e-07 29.0 0.3 2.2 2 0 0 2 2 2 1 Acyltransferase C-terminus Abhydrolase_6 PF12697.7 EAU92911.1 - 7.4e-07 30.0 0.2 0.00043 21.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU92911.1 - 2.1e-06 27.2 0.0 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EAU92911.1 - 0.00074 19.2 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Red1 PF07964.11 EAU92912.2 - 6.5 4.9 11.3 8.7 4.4 11.3 1.1 1 0 0 1 1 1 0 Rec10 / Red1 MIT PF04212.18 EAU92913.2 - 0.00012 22.0 0.2 0.00025 21.0 0.2 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3543 PF12063.8 EAU92913.2 - 0.015 14.7 1.1 0.025 14.0 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Septin PF00735.18 EAU92914.2 - 2.7e-111 371.4 0.5 3.5e-111 371.0 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EAU92914.2 - 6.7e-07 29.4 0.0 2.2e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU92914.2 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EAU92914.2 - 0.0033 17.0 0.1 0.11 12.0 0.0 2.5 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EAU92914.2 - 0.0083 16.2 3.0 0.54 10.3 0.0 3.0 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 EAU92914.2 - 0.044 13.7 4.2 0.063 13.2 0.4 2.9 3 1 0 3 3 3 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EAU92914.2 - 0.048 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.13 EAU92914.2 - 0.07 12.2 0.2 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EAU92914.2 - 0.19 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EAU92914.2 - 0.24 11.7 1.4 0.8 10.0 0.1 2.3 2 2 0 2 2 2 0 AAA domain DUF4140 PF13600.6 EAU92914.2 - 0.89 10.0 4.8 4.1 7.9 4.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) MutS_V PF00488.21 EAU92915.2 - 1e-69 234.3 0.0 1.8e-69 233.6 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EAU92915.2 - 2.9e-31 109.2 0.8 6e-31 108.2 0.8 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EAU92915.2 - 4.5e-22 78.4 0.0 9.2e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EAU92915.2 - 1.1e-12 48.3 0.0 2.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 EAU92915.2 - 0.00027 20.6 0.1 0.00073 19.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EAU92915.2 - 0.0084 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EAU92915.2 - 0.014 15.9 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EAU92915.2 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Oxysterol_BP PF01237.18 EAU92917.2 - 3.4e-112 375.0 0.1 1.5e-111 372.9 0.0 2.0 2 1 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.6 EAU92917.2 - 1.3e-17 63.8 1.5 1.3e-16 60.7 0.1 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EAU92917.2 - 0.00017 22.0 0.7 0.0017 18.8 0.7 2.5 1 1 0 1 1 1 1 PH domain SASRP1 PF15160.6 EAU92917.2 - 0.82 9.3 3.3 1.3 8.7 1.6 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 6PGD PF00393.19 EAU92918.1 - 1.9e-125 418.0 0.0 2.4e-125 417.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EAU92918.1 - 1.6e-50 171.4 0.0 2.3e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EAU92918.1 - 0.00015 22.3 0.2 0.00029 21.4 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EAU92918.1 - 0.027 14.1 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.6 EAU92918.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 EAU92918.1 - 0.14 11.5 0.1 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoatB PF10389.9 EAU92918.1 - 1.8 8.5 4.1 11 6.0 0.8 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B Asn_synthase PF00733.21 EAU92919.2 - 1.2e-20 74.5 0.1 1.6e-08 34.7 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase QueC PF06508.13 EAU92919.2 - 0.095 12.2 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Band_7 PF01145.25 EAU92920.1 - 2.9e-24 86.0 5.1 7.7e-24 84.7 5.0 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EAU92920.1 - 0.00012 21.2 3.1 0.00016 20.9 3.1 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Peptidase_S66 PF02016.15 EAU92920.1 - 0.17 12.0 0.5 0.42 10.7 0.3 1.7 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain Atg14 PF10186.9 EAU92920.1 - 0.47 9.5 1.6 0.62 9.1 1.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RRM_1 PF00076.22 EAU92921.2 - 1.9e-54 181.4 0.0 9e-19 67.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EAU92921.2 - 2.1e-09 37.0 0.0 4.7e-05 23.0 0.0 3.0 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EAU92921.2 - 2.1e-07 30.7 0.0 7.9e-05 22.4 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EAU92921.2 - 0.0016 18.4 0.1 1.8 8.6 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EAU92921.2 - 0.009 16.1 0.0 4.4 7.4 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 EAU92921.2 - 0.014 15.5 0.0 0.35 11.0 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 EAU92921.2 - 0.09 13.0 0.0 25 5.0 0.0 2.9 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter ATG16 PF08614.11 EAU92922.1 - 7.9e-52 176.4 25.2 7.9e-52 176.4 25.2 1.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) YabA PF06156.13 EAU92922.1 - 0.037 14.7 4.1 0.037 14.7 4.1 3.1 1 1 2 3 3 3 0 Initiation control protein YabA FlaC_arch PF05377.11 EAU92922.1 - 0.23 11.9 9.0 0.44 11.0 0.8 3.0 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EAU92922.1 - 0.61 10.1 9.8 0.92 9.5 5.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EAU92922.1 - 1.4 8.2 13.0 2.7 7.3 12.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MAD PF05557.13 EAU92922.1 - 1.5 7.1 25.0 0.089 11.1 19.6 1.5 2 0 0 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 EAU92922.1 - 2.5 8.5 21.1 5.9 7.3 16.8 2.1 1 1 1 2 2 2 0 Fez1 DASH_Dam1 PF08653.10 EAU92922.1 - 2.8 7.8 5.1 8 6.3 0.2 3.2 4 0 0 4 4 4 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 EAU92922.1 - 3.4 7.9 14.0 8.2 6.6 7.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3574 PF12098.8 EAU92922.1 - 3.4 7.5 6.4 27 4.6 0.4 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3574) DUF16 PF01519.16 EAU92922.1 - 6 7.4 12.1 49 4.5 11.2 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ras PF00071.22 EAU92923.1 - 8.4e-58 194.5 0.1 9.8e-58 194.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU92923.1 - 2.2e-32 111.8 0.0 3.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU92923.1 - 1.8e-13 50.3 0.0 2.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EAU92923.1 - 1.3e-07 31.7 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EAU92923.1 - 1.1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EAU92923.1 - 1.1e-05 25.0 0.0 0.00045 19.8 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EAU92923.1 - 0.00011 22.2 0.1 0.0045 16.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 EAU92923.1 - 0.0009 19.1 0.2 0.044 13.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 EAU92923.1 - 0.0019 17.5 0.2 0.046 13.0 0.0 2.2 2 1 0 2 2 2 1 Septin cobW PF02492.19 EAU92923.1 - 0.0022 17.6 0.0 0.0053 16.4 0.0 1.6 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EAU92923.1 - 0.0025 17.6 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EAU92923.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EAU92923.1 - 0.0071 16.6 0.0 0.021 15.1 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EAU92923.1 - 0.0083 16.5 0.1 0.015 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EAU92923.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EAU92923.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EAU92923.1 - 0.021 14.8 0.0 0.053 13.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EAU92923.1 - 0.049 13.5 0.4 0.091 12.7 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EAU92923.1 - 0.049 13.5 0.1 0.093 12.6 0.0 1.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 EAU92923.1 - 0.079 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_75 PF07335.11 EAU92923.1 - 0.082 13.2 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 AAA_18 PF13238.6 EAU92923.1 - 0.1 13.2 0.1 0.92 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 EAU92926.2 - 2e-49 167.2 0.1 2.3e-49 167.0 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glucosamine_iso PF01182.20 EAU92927.1 - 1.4e-74 250.8 0.0 1.6e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PXA PF02194.15 EAU92928.2 - 1.3e-46 158.9 0.4 3.9e-46 157.3 0.1 1.9 2 0 0 2 2 2 1 PXA domain DUF3527 PF12043.8 EAU92928.2 - 0.18 11.3 0.4 0.25 10.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) UPF0052 PF01933.18 EAU92930.2 - 8e-46 156.6 0.0 1.1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Chorismate_synt PF01264.21 EAU92931.1 - 2.5e-139 463.5 0.0 3e-139 463.3 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SAP30_Sin3_bdg PF13867.6 EAU92932.1 - 0.0096 16.2 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Octopine_DH PF02317.17 EAU92932.1 - 0.044 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Presenilin PF01080.17 EAU92933.1 - 6.1 5.5 7.6 8.9 5.0 7.6 1.2 1 0 0 1 1 1 0 Presenilin SKG6 PF08693.10 EAU92934.2 - 0.0029 17.0 1.6 0.0029 17.0 1.6 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain ABC_tran PF00005.27 EAU92935.2 - 2.5e-42 144.6 0.1 4.9e-23 82.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EAU92935.2 - 2.3e-22 78.8 3.9 2.3e-22 78.8 3.9 3.5 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EAU92935.2 - 5.9e-17 62.4 7.5 0.00021 21.2 0.1 4.9 5 1 1 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EAU92935.2 - 1.8e-08 34.1 0.0 0.0037 16.7 0.0 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EAU92935.2 - 1e-06 28.8 0.0 0.0085 16.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU92935.2 - 2.3e-06 27.6 0.1 0.091 12.7 0.1 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EAU92935.2 - 2.6e-06 27.1 0.2 0.032 14.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EAU92935.2 - 5.3e-06 26.5 0.0 0.12 12.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EAU92935.2 - 9.1e-06 26.0 0.2 0.1 12.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EAU92935.2 - 0.00016 22.1 5.1 0.12 12.8 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain MeaB PF03308.16 EAU92935.2 - 0.00023 20.2 0.2 0.085 11.8 0.0 2.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EAU92935.2 - 0.00029 20.7 11.3 0.39 10.4 0.1 4.1 5 0 0 5 5 5 2 AAA ATPase domain AAA_24 PF13479.6 EAU92935.2 - 0.00031 20.5 0.0 0.57 9.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EAU92935.2 - 0.00091 19.5 2.0 2.6 8.3 0.1 3.7 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EAU92935.2 - 0.0036 17.8 1.8 2.3 8.8 0.1 4.1 3 1 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EAU92935.2 - 0.0044 16.8 0.6 0.57 9.9 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EAU92935.2 - 0.0055 16.9 1.2 2 8.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.6 EAU92935.2 - 0.0063 17.0 23.9 0.07 13.6 0.0 4.9 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.22 EAU92935.2 - 0.0079 16.6 0.0 4.2 7.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 EAU92935.2 - 0.01 15.9 1.0 0.97 9.5 0.0 3.3 3 2 0 3 3 3 0 Dynamin family DUF815 PF05673.13 EAU92935.2 - 0.01 15.0 0.0 0.53 9.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 EAU92935.2 - 0.038 14.2 0.1 12 6.1 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EAU92935.2 - 0.041 14.0 0.1 0.041 14.0 0.1 3.8 3 1 1 4 4 4 0 Helicase HerA, central domain NTPase_1 PF03266.15 EAU92935.2 - 0.05 13.5 0.0 7.3 6.5 0.0 2.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EAU92935.2 - 0.062 12.5 2.8 6.1 5.9 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.29 EAU92935.2 - 0.063 13.7 1.1 16 5.9 0.1 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EAU92935.2 - 0.063 12.9 0.2 12 5.4 0.0 3.3 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 EAU92935.2 - 0.13 12.3 0.3 13 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EAU92935.2 - 0.21 11.6 1.6 27 4.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EAU92935.2 - 0.23 11.7 2.3 4.8 7.5 0.1 3.8 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DNA_topoisoIV PF00521.20 EAU92936.2 - 7.5e-121 404.0 0.6 7.5e-121 404.0 0.6 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EAU92936.2 - 8.2e-52 174.8 1.6 8.2e-52 174.8 1.6 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EAU92936.2 - 1.6e-30 105.8 2.1 3.5e-30 104.7 2.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EAU92936.2 - 2.2e-12 47.5 0.0 4.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EAU92936.2 - 1.4e-08 34.9 0.2 6.7e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Toprim domain Ntox17 PF15524.6 EAU92936.2 - 0.018 15.3 0.6 0.75 10.1 0.1 2.8 2 0 0 2 2 2 0 Novel toxin 17 Y_phosphatase PF00102.27 EAU92937.2 - 1.3e-37 129.6 0.0 2e-22 79.9 0.0 4.3 2 1 1 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 EAU92937.2 - 1.1e-06 29.1 0.0 5.7e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EAU92937.2 - 0.017 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EAU92937.2 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EAU92937.2 - 0.08 13.1 0.0 2 8.5 0.0 2.5 1 1 1 2 2 2 0 Inositol hexakisphosphate WW PF00397.26 EAU92938.2 - 4e-05 23.6 1.7 0.0001 22.3 1.7 1.8 1 0 0 1 1 1 1 WW domain Fe-S_biosyn PF01521.20 EAU92939.2 - 2.5e-21 75.9 0.0 3.3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis BAR PF03114.18 EAU92940.1 - 5.6e-40 137.5 2.8 7.7e-40 137.0 2.8 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EAU92940.1 - 5.7e-16 57.9 0.1 9.3e-16 57.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EAU92940.1 - 2.9e-14 52.6 0.1 5e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EAU92940.1 - 7.9e-10 38.3 0.0 1.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ku_PK_bind PF08785.11 EAU92940.1 - 0.033 14.3 0.5 0.1 12.7 0.5 1.8 1 0 0 1 1 1 0 Ku C terminal domain like OmpH PF03938.14 EAU92940.1 - 0.036 14.4 2.9 0.084 13.2 1.9 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Vps5 PF09325.10 EAU92940.1 - 0.25 10.8 5.2 1 8.9 5.2 2.0 1 1 0 1 1 1 0 Vps5 C terminal like HIP1_clath_bdg PF16515.5 EAU92940.1 - 0.43 11.2 2.7 4.2 8.0 0.6 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SBDS PF01172.18 EAU92941.1 - 2.3e-36 123.7 1.3 4.7e-36 122.7 1.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EAU92941.1 - 2.8e-35 120.8 0.5 5.6e-35 119.9 0.5 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain Phage_TAC_5 PF08890.11 EAU92941.1 - 0.04 13.9 0.1 0.094 12.7 0.1 1.7 1 1 0 1 1 1 0 Phage XkdN-like tail assembly chaperone protein, TAC Glyco_trans_1_4 PF13692.6 EAU92942.2 - 1.9e-06 28.3 0.0 3.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EAU92942.2 - 2.2e-06 28.2 0.2 2.2e-06 28.2 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 EAU92942.2 - 0.00064 19.3 0.0 0.00097 18.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EAU92942.2 - 0.001 19.1 1.9 0.002 18.2 1.9 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EAU92942.2 - 0.0012 19.2 0.0 0.0023 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Nfu_N PF08712.11 EAU92943.2 - 1.2e-29 102.2 0.0 3e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EAU92943.2 - 8.3e-28 96.3 0.2 1.6e-27 95.4 0.2 1.5 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 EAU92943.2 - 0.0034 17.5 0.5 0.0068 16.5 0.5 1.4 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Copper-fist PF00649.18 EAU92944.2 - 3.8e-21 74.3 1.5 3.8e-21 74.3 1.5 2.8 2 0 0 2 2 2 1 Copper fist DNA binding domain UQ_con PF00179.26 EAU92945.2 - 3.8e-28 97.9 0.0 4.6e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EAU92945.2 - 0.00028 20.6 0.0 0.053 13.2 0.0 2.1 1 1 1 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 EAU92945.2 - 0.057 13.3 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.11 EAU92945.2 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Ricin_B_lectin PF00652.22 EAU92946.2 - 5.8e-09 36.3 0.0 1.3 9.3 0.0 4.3 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 EAU92946.2 - 0.0001 21.9 2.7 4.1 7.0 0.1 4.4 4 0 0 4 4 4 3 Cytolethal distending toxin A/C domain Glyoxalase_3 PF13468.6 EAU92946.2 - 0.0018 18.4 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain CLTH PF10607.9 EAU92947.2 - 6.4e-22 78.0 0.0 1.4e-21 76.9 0.0 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EAU92947.2 - 9.2e-14 51.6 0.3 2.3e-13 50.3 0.3 1.6 1 1 0 1 1 1 1 SPRY domain LisH PF08513.11 EAU92947.2 - 4.4e-05 23.3 0.9 7.3e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 LisH UMP1 PF05348.11 EAU92948.1 - 6.7e-34 116.6 0.1 7.8e-34 116.4 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MFAP1 PF06991.11 EAU92949.2 - 7.2e-69 231.9 24.9 7.2e-69 231.9 24.9 3.4 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing NAD_binding_8 PF13450.6 EAU92949.2 - 2.5e-15 56.5 0.2 8.5e-14 51.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain zf-CCHC PF00098.23 EAU92949.2 - 0.031 14.4 1.7 0.072 13.2 1.7 1.7 1 0 0 1 1 1 0 Zinc knuckle Pyr_redox_2 PF07992.14 EAU92949.2 - 0.14 11.3 0.1 0.33 10.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SprT-like PF10263.9 EAU92950.2 - 4.5e-30 103.8 1.1 8.9e-30 102.9 1.1 1.5 1 0 0 1 1 1 1 SprT-like family Mucin PF01456.17 EAU92950.2 - 0.69 9.9 10.1 1.4 9.0 10.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.22 EAU92951.1 - 5.4e-59 200.2 0.0 8.8e-34 117.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 RTX_C PF08339.10 EAU92951.1 - 0.013 15.5 0.0 0.074 13.1 0.1 2.0 2 0 0 2 2 2 0 RTX C-terminal domain GP11 PF08677.10 EAU92951.1 - 0.15 11.6 0.0 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 GP11 baseplate wedge protein Ribosomal_S14 PF00253.21 EAU92952.2 - 1.1e-13 50.7 3.6 1.2e-13 50.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PUF PF00806.19 EAU92953.2 - 5.1e-60 195.9 12.4 9.7e-08 31.3 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat RA PF00788.23 EAU92953.2 - 0.17 12.5 0.2 1.3 9.7 0.0 2.2 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Cullin PF00888.22 EAU92956.1 - 5.3e-05 22.1 0.0 7.2e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family Sen15 PF09631.10 EAU92956.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Sen15 protein HMG_box PF00505.19 EAU92957.2 - 1.1e-12 48.2 2.2 2.2e-12 47.2 2.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EAU92957.2 - 1.3e-05 25.7 0.5 3e-05 24.5 0.5 1.5 1 0 0 1 1 1 1 HMG-box domain NETI PF14044.6 EAU92957.2 - 0.071 12.9 0.6 0.17 11.6 0.4 1.7 1 1 0 1 1 1 0 NETI protein HMG_box_5 PF14887.6 EAU92957.2 - 0.09 12.8 0.9 0.16 11.9 0.9 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DHO_dh PF01180.21 EAU92958.1 - 2.4e-15 56.5 0.0 4.4e-15 55.7 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase CLU_N PF15044.6 EAU92958.1 - 0.14 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term TRAPP PF04051.16 EAU92959.2 - 2.2e-43 147.5 0.0 2.6e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BTB PF00651.31 EAU92960.1 - 0.0012 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 EAU92961.2 - 1.5e-32 111.1 8.3 2.1e-05 25.2 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EAU92961.2 - 4e-09 35.7 0.2 0.00079 18.2 0.0 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EAU92961.2 - 0.00024 21.3 0.0 9.9 6.5 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 EAU92961.2 - 0.0025 17.3 0.0 0.072 12.5 0.0 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF5046) DUF1664 PF07889.12 EAU92961.2 - 0.85 9.7 2.5 1.4 8.9 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5556 PF17711.1 EAU92962.2 - 0.005 16.8 0.4 2 8.3 0.0 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5556) T3SS_TC PF06511.11 EAU92962.2 - 0.078 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Type III secretion systems tip complex components CS PF04969.16 EAU92963.1 - 2.9e-05 25.0 0.0 4.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 CS domain PLDc_3 PF13918.6 EAU92963.1 - 0.062 13.0 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 PLD-like domain CBM_19 PF03427.13 EAU92965.2 - 0.0016 18.4 0.9 0.005 16.8 0.9 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) HAD_2 PF13419.6 EAU92966.2 - 1.3e-23 84.0 0.0 1.6e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EAU92966.2 - 1.8e-16 61.1 0.1 3.8e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EAU92966.2 - 2.3e-08 34.0 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EAU92966.2 - 0.0011 19.3 0.1 0.0023 18.4 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EAU92966.2 - 0.009 16.1 0.1 0.14 12.3 0.1 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Romo1 PF10247.9 EAU92967.2 - 6.7e-20 71.2 11.9 4.1e-13 49.5 0.7 2.2 1 1 1 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 AAA_6 PF12774.7 EAU92970.2 - 2.4e-127 424.4 0.0 1.9e-126 421.5 0.0 2.6 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EAU92970.2 - 5.4e-116 388.0 8.4 5.4e-116 388.0 8.4 3.4 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EAU92970.2 - 2.1e-73 246.1 0.9 2.1e-73 246.1 0.9 4.0 5 1 1 6 6 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 EAU92970.2 - 1.3e-68 231.2 0.0 7.6e-68 228.6 0.0 2.4 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EAU92970.2 - 2.8e-52 177.9 0.1 2.8e-52 177.9 0.1 2.3 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EAU92970.2 - 6.5e-43 146.3 0.0 2.5e-36 124.9 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EAU92970.2 - 3e-38 131.7 7.5 5.3e-38 130.9 7.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EAU92970.2 - 4.8e-37 127.3 0.0 9.6e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EAU92970.2 - 1e-30 106.2 0.0 1.5e-29 102.5 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EAU92970.2 - 9.4e-29 100.2 0.0 7.3e-13 48.7 0.0 5.8 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EAU92970.2 - 2.2e-17 63.4 0.1 5.1e-16 58.9 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EAU92970.2 - 6.2e-13 49.3 0.3 0.0023 18.3 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EAU92970.2 - 1.4e-12 48.0 1.4 0.0066 16.7 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 EAU92970.2 - 8.8e-11 42.1 6.7 0.12 12.6 0.0 6.6 6 0 0 6 6 6 3 AAA domain AAA_16 PF13191.6 EAU92970.2 - 7.9e-09 36.1 0.0 0.57 10.5 0.0 6.5 6 0 0 6 6 5 1 AAA ATPase domain AAA_18 PF13238.6 EAU92970.2 - 1.2e-07 32.3 0.1 0.65 10.6 0.0 5.5 4 0 0 4 4 4 2 AAA domain T2SSE PF00437.20 EAU92970.2 - 3.5e-06 26.3 0.0 0.017 14.2 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EAU92970.2 - 3.8e-06 26.4 0.4 0.65 9.3 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 EAU92970.2 - 6.7e-06 25.6 0.0 0.31 10.4 0.0 3.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_19 PF13245.6 EAU92970.2 - 6.3e-05 23.3 3.1 0.31 11.4 0.0 5.3 5 0 0 5 5 5 1 AAA domain AAA_30 PF13604.6 EAU92970.2 - 0.0002 21.1 0.2 26 4.5 0.0 4.6 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 EAU92970.2 - 0.00023 20.8 0.0 0.74 9.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 EAU92970.2 - 0.00044 20.4 2.1 0.0012 19.1 0.0 2.8 3 0 0 3 3 2 1 AAA+ lid domain IstB_IS21 PF01695.17 EAU92970.2 - 0.00056 19.7 0.4 0.77 9.5 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein Rad17 PF03215.15 EAU92970.2 - 0.0023 17.9 1.1 24 4.8 0.0 5.1 6 0 0 6 6 5 0 Rad17 P-loop domain AAA_24 PF13479.6 EAU92970.2 - 0.0044 16.8 1.0 18 5.0 0.0 4.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EAU92970.2 - 0.0052 17.3 2.6 13 6.3 0.0 4.7 4 0 0 4 4 3 0 ABC transporter RNA_helicase PF00910.22 EAU92970.2 - 0.0099 16.3 0.0 25 5.3 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_21 PF13304.6 EAU92970.2 - 0.013 15.3 0.0 9.6 5.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system LOH1CR12 PF10158.9 EAU92970.2 - 0.017 15.2 15.5 0.11 12.5 0.4 4.1 4 0 0 4 4 2 0 Tumour suppressor protein AAA_25 PF13481.6 EAU92970.2 - 0.023 14.3 0.2 0.62 9.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 EAU92970.2 - 0.028 14.4 0.4 19 5.3 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EAU92970.2 - 0.04 13.9 0.1 33 4.4 0.0 4.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Phostensin_N PF13916.6 EAU92970.2 - 0.046 14.1 0.2 0.2 12.0 0.0 2.1 2 0 0 2 2 1 0 PP1-regulatory protein, Phostensin N-terminal DEAD PF00270.29 EAU92970.2 - 0.047 13.4 0.0 7.4 6.3 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase SRP54 PF00448.22 EAU92970.2 - 0.048 13.3 0.7 42 3.7 0.0 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EAU92970.2 - 0.086 12.8 2.4 39 4.1 0.1 4.7 5 0 0 5 5 3 0 NACHT domain RuvB_N PF05496.12 EAU92970.2 - 0.088 12.6 0.1 3.8 7.3 0.0 3.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 EAU92970.2 - 0.11 12.2 0.2 12 5.7 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 EAU92970.2 - 0.18 11.6 1.3 0.87 9.4 0.5 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF4988 PF16378.5 EAU92970.2 - 1.6 8.4 5.0 0.78 9.4 1.1 2.6 3 0 0 3 3 2 0 Domain of unknown function Phage_GP20 PF06810.11 EAU92970.2 - 2 8.2 22.2 0.21 11.4 3.9 4.0 3 0 0 3 3 3 0 Phage minor structural protein GP20 ERM PF00769.19 EAU92970.2 - 5.4 6.8 32.5 0.43 10.4 5.4 3.2 3 0 0 3 3 2 0 Ezrin/radixin/moesin family GHMP_kinases_N PF00288.26 EAU92971.1 - 5.9e-10 39.2 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EAU92971.1 - 0.0021 18.4 0.0 0.0064 16.8 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal DUF3512 PF12024.8 EAU92972.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.16 EAU92973.1 - 2.4e-09 37.0 0.1 3.7e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MFS_1 PF07690.16 EAU92977.2 - 1.8e-13 50.2 7.2 4.3e-13 48.9 1.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EAU92977.2 - 0.0084 15.0 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 MFS_1 like family Fapy_DNA_glyco PF01149.24 EAU92978.2 - 1.3e-28 100.0 0.0 2e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EAU92978.2 - 1.7e-21 76.0 0.0 3.5e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EAU92978.2 - 0.016 14.0 0.0 0.037 12.8 0.0 1.6 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 EAU92978.2 - 0.068 13.6 0.1 0.38 11.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S13/S18 DUF5505 PF17610.2 EAU92978.2 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5505) Utp12 PF04003.12 EAU92979.1 - 3.7e-23 81.9 0.0 7.3e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 EAU92979.1 - 0.00015 22.5 1.1 0.1 13.5 0.3 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU92979.1 - 0.017 15.4 0.0 12 6.2 0.0 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 EAU92980.2 - 5.2e-77 258.8 0.3 2.3e-76 256.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU92980.2 - 2.1e-36 125.6 0.8 3.5e-36 124.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU92980.2 - 0.00028 20.3 0.0 0.00028 20.3 0.0 2.0 2 0 0 2 2 1 1 Kinase-like Haspin_kinase PF12330.8 EAU92980.2 - 0.00033 19.7 3.0 0.0017 17.3 0.0 2.7 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EAU92980.2 - 0.0085 16.0 2.2 0.07 13.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family TFIIA PF03153.13 EAU92980.2 - 0.051 13.6 22.9 0.065 13.2 22.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 EAU92980.2 - 0.071 13.2 0.1 0.074 13.1 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 EAU92980.2 - 0.072 14.1 5.9 0.12 13.3 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EAU92980.2 - 0.26 10.9 25.3 0.43 10.2 25.3 1.4 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 EAU92980.2 - 0.28 10.1 5.9 0.36 9.7 5.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.14 EAU92980.2 - 0.68 9.9 10.3 0.92 9.4 10.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2722 PF10846.8 EAU92980.2 - 0.87 8.5 21.9 1.2 7.9 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PAT1 PF09770.9 EAU92980.2 - 1 7.5 17.0 1.3 7.2 17.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 EAU92980.2 - 3.2 6.4 6.6 4.4 6.0 6.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4770 PF15994.5 EAU92980.2 - 4 7.6 13.5 8 6.7 13.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) TMEM51 PF15345.6 EAU92980.2 - 5.1 6.9 14.1 8 6.2 14.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 OATP PF03137.20 EAU92980.2 - 5.4 5.2 5.6 7.2 4.8 5.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Endostatin PF06482.11 EAU92980.2 - 5.5 6.4 10.9 8.3 5.8 10.9 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Pex14_N PF04695.13 EAU92980.2 - 7.8 7.1 20.7 15 6.2 20.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 EAU92980.2 - 8.1 6.4 15.9 13 5.8 15.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF3464 PF11947.8 EAU92980.2 - 8.5 6.1 6.2 15 5.3 6.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DEAD PF00270.29 EAU92983.1 - 5.3e-37 127.3 0.1 8.4e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU92983.1 - 2.4e-27 95.5 0.1 5.6e-25 87.8 0.0 2.6 2 1 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EAU92983.1 - 6.8e-09 36.0 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NgoMIV_restric PF09015.10 EAU92983.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 NgoMIV restriction enzyme VIT PF08487.10 EAU92984.1 - 4e-23 81.8 0.0 6.9e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EAU92984.1 - 3.6e-20 72.5 0.0 8.2e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAU92984.1 - 7.2e-10 39.5 0.0 2e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EAU92984.1 - 5.1e-09 36.6 0.0 9.6e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EAU92984.1 - 0.0031 16.9 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 EAU92984.1 - 0.0043 16.9 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Mito_carr PF00153.27 EAU92985.2 - 2.9e-55 184.2 2.3 8.9e-20 70.4 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_43 PF04616.14 EAU92986.2 - 2e-17 63.4 2.5 3.2e-17 62.8 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 EAU92986.2 - 0.0014 18.9 1.0 0.0028 17.9 1.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) OLF PF02191.16 EAU92986.2 - 0.024 14.2 0.2 0.042 13.4 0.2 1.3 1 0 0 1 1 1 0 Olfactomedin-like domain DEAD PF00270.29 EAU92987.1 - 5.5e-39 133.7 0.3 1e-38 132.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU92987.1 - 7e-26 90.8 0.0 2.3e-25 89.1 0.0 1.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU92987.1 - 6.8e-07 29.4 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EAU92987.1 - 0.25 11.6 0.7 0.89 9.8 0.7 1.9 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EAU92987.1 - 5.3 6.3 7.2 4.4 6.6 0.0 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PolyA_pol PF01743.20 EAU92989.2 - 5e-17 62.5 0.1 2e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EAU92989.2 - 1.8e-05 24.4 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A AGTRAP PF06396.11 EAU92991.2 - 0.00019 21.3 1.4 0.00042 20.1 1.4 1.7 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Reticulon PF02453.17 EAU92991.2 - 0.024 14.6 3.7 0.025 14.5 2.9 1.4 1 1 0 1 1 1 0 Reticulon TMEM135_C_rich PF15982.5 EAU92994.1 - 0.00029 21.5 0.2 0.00074 20.1 0.2 1.6 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Pex24p PF06398.11 EAU92995.2 - 1.8e-09 37.1 4.5 2.7e-09 36.5 4.5 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin UPF0175 PF03683.13 EAU92995.2 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HSCB_C PF07743.13 EAU92996.2 - 3.9e-19 68.9 4.8 3.9e-19 68.9 4.8 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EAU92996.2 - 0.00033 20.7 0.1 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Herpes_UL14 PF03580.14 EAU92996.2 - 0.0058 16.9 0.1 0.0093 16.2 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus UL14-like protein HNF-1_N PF04814.13 EAU92996.2 - 0.12 13.0 0.2 0.16 12.6 0.2 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus zinc_ribbon_12 PF11331.8 EAU92996.2 - 0.13 12.1 2.5 0.25 11.2 0.2 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain DUF35_N PF12172.8 EAU92996.2 - 0.54 10.2 4.5 1.4 8.9 4.5 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.6 EAU92996.2 - 7.9 6.0 7.6 0.49 9.9 0.7 1.9 1 1 1 2 2 2 0 zinc-ribbon domain Ribosomal_S24e PF01282.19 EAU92997.2 - 6.4e-34 115.7 0.0 1.4e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S24e HA2 PF04408.23 EAU92997.2 - 7.8e-17 61.5 1.8 9.4e-17 61.3 0.0 2.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EAU92997.2 - 1.4e-13 51.1 0.0 3.6e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 EAU92997.2 - 6.6e-08 33.1 0.0 0.00033 21.3 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 EAU92997.2 - 5.3e-06 26.3 0.1 1.5e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EAU92997.2 - 0.0019 18.5 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EAU92997.2 - 0.0033 17.8 0.0 0.0086 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dicer_dimer PF03368.14 EAU92997.2 - 0.014 15.5 0.0 0.047 13.8 0.0 1.9 1 0 0 1 1 1 0 Dicer dimerisation domain DUF2057 PF09829.9 EAU92997.2 - 0.17 12.0 0.0 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Actin PF00022.19 EAU92998.2 - 2.1e-112 375.7 0.0 2.5e-111 372.2 0.0 1.9 1 1 0 1 1 1 1 Actin SVIP PF15811.5 EAU93000.2 - 0.00032 21.1 4.3 0.00053 20.4 4.3 1.5 1 0 0 1 1 1 1 Small VCP/p97-interacting protein WLM PF08325.10 EAU93000.2 - 0.057 13.5 2.7 0.12 12.4 2.7 1.6 1 1 0 1 1 1 0 WLM domain DEAD PF00270.29 EAU93002.1 - 2.2e-50 170.9 0.0 2.7e-48 164.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU93002.1 - 2.1e-33 115.0 0.0 4.8e-31 107.4 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU93002.1 - 3.3e-05 24.0 0.1 0.0066 16.5 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 EAU93002.1 - 0.0018 16.6 20.0 0.0018 16.6 20.0 2.1 2 0 0 2 2 2 1 Nop14-like family MscS_TM PF12794.7 EAU93002.1 - 1.3 7.8 4.6 2.9 6.7 4.6 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RasGEF PF00617.19 EAU93003.2 - 5.2e-30 104.9 0.0 8.2e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EAU93003.2 - 2.1e-10 40.8 0.0 6.5e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 EAU93003.2 - 1.2e-05 24.9 0.0 0.00017 21.2 0.0 2.2 2 0 0 2 2 2 1 Ras family Arf PF00025.21 EAU93003.2 - 0.0047 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SurE PF01975.17 EAU93004.2 - 6.2e-46 156.6 0.0 7.7e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_L15e PF00827.17 EAU93005.2 - 1e-90 302.6 9.9 1.3e-90 302.3 9.9 1.1 1 0 0 1 1 1 1 Ribosomal L15 UL17 PF17640.2 EAU93005.2 - 0.0066 16.4 1.8 0.0066 16.4 1.8 1.8 2 0 0 2 2 2 1 Uncharacterized UL17 MFS_1 PF07690.16 EAU93006.2 - 5.3e-12 45.3 10.6 6.6e-12 45.0 10.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PEP-utilisers_N PF05524.13 EAU93006.2 - 0.16 12.1 0.3 0.3 11.3 0.3 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4481 PF14800.6 EAU93007.1 - 0.077 12.5 1.9 0.097 12.1 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) SAD_SRA PF02182.17 EAU93010.2 - 2e-55 186.8 0.1 3.3e-55 186.1 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain DUF1664 PF07889.12 EAU93011.1 - 0.99 9.5 5.1 9.2 6.3 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) XhlA PF10779.9 EAU93011.1 - 4.8 7.5 12.4 0.28 11.4 0.7 3.6 3 1 1 4 4 4 0 Haemolysin XhlA DUF948 PF06103.11 EAU93011.1 - 5.4 7.3 5.8 6.7 7.0 0.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mpp10 PF04006.12 EAU93012.1 - 2.7e-117 392.8 52.1 2.7e-117 392.8 52.1 1.6 1 1 0 2 2 2 1 Mpp10 protein Abhydrolase_9_N PF15420.6 EAU93013.1 - 0.37 10.8 6.0 0.031 14.3 1.2 1.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF2208 PF09973.9 EAU93013.1 - 6.8 6.2 6.7 0.86 9.2 1.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Lyase_8 PF02278.18 EAU93014.2 - 1e-67 228.4 0.1 1.9e-67 227.5 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 EAU93014.2 - 6.4e-20 71.3 0.0 1.1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 EAU93014.2 - 2e-11 44.2 1.9 4.4e-11 43.1 1.9 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain dUTPase PF00692.19 EAU93014.2 - 0.0097 15.6 0.3 0.034 13.8 0.1 1.9 2 0 0 2 2 2 1 dUTPase Ribosomal_L32p PF01783.23 EAU93016.2 - 2.6e-15 56.4 5.7 3.8e-15 55.9 5.3 1.5 1 1 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 EAU93016.2 - 0.0034 17.3 2.1 0.006 16.5 2.1 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 EAU93016.2 - 0.17 12.0 2.1 0.92 9.7 0.3 2.2 1 1 1 2 2 2 0 Zinc ribbon domain ETC_C1_NDUFA5 PF04716.14 EAU93017.1 - 2.9e-27 94.2 0.1 4.3e-27 93.7 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region LSM PF01423.22 EAU93018.2 - 4.3e-16 58.4 0.1 6.1e-16 57.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EAU93018.2 - 0.017 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Hfq protein PHD PF00628.29 EAU93019.2 - 2e-10 40.4 8.2 2e-10 40.4 8.2 2.0 2 0 0 2 2 2 1 PHD-finger PHD_4 PF16866.5 EAU93019.2 - 0.92 9.6 5.5 2.8 8.1 5.5 1.9 1 0 0 1 1 1 0 PHD-finger HABP4_PAI-RBP1 PF04774.15 EAU93020.1 - 1.9e-13 51.3 8.3 1.9e-13 51.3 8.3 2.8 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.22 EAU93021.1 - 1.8e-22 80.0 0.0 5.1e-22 78.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 EAU93023.2 - 1.8e-40 139.0 0.0 1e-38 133.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93023.2 - 8.7e-16 58.0 0.0 2.1e-14 53.4 0.0 2.9 2 2 1 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EAU93023.2 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAU93023.2 - 0.0026 17.2 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EAU93023.2 - 0.0098 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EAU93023.2 - 0.061 12.1 1.2 0.081 11.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase SelP_N PF04592.14 EAU93023.2 - 0.13 11.6 4.2 0.21 11.0 4.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4551 PF15087.6 EAU93023.2 - 8.5 5.1 7.9 12 4.6 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GTP_EFTU PF00009.27 EAU93024.1 - 1.1e-53 181.7 0.1 1.6e-53 181.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAU93024.1 - 9.3e-43 145.1 0.0 2.2e-42 143.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAU93024.1 - 8.8e-14 51.7 1.3 2.6e-13 50.2 0.7 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAU93024.1 - 0.00038 20.5 0.1 0.0086 16.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 EAU93024.1 - 0.066 13.3 0.2 0.95 9.5 0.1 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU_D4 PF14578.6 EAU93024.1 - 3.3 7.7 6.6 0.28 11.1 0.8 2.2 3 0 0 3 3 3 0 Elongation factor Tu domain 4 DLH PF01738.18 EAU93025.2 - 6.2e-15 55.3 0.0 1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 EAU93025.2 - 0.013 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Elong_Iki1 PF10483.9 EAU93026.2 - 8.4e-12 45.2 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Elongator subunit Iki1 Aminotran_1_2 PF00155.21 EAU93028.2 - 2e-85 287.1 0.0 2.3e-85 287.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.20 EAU93029.1 - 6.5e-77 258.7 0.0 9e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EAU93029.1 - 9.1e-08 32.0 0.1 1.7e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EAU93029.1 - 0.018 14.5 0.2 2.6 7.4 0.0 2.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) MCM_N PF14551.6 EAU93029.1 - 0.09 13.4 0.0 0.21 12.2 0.0 1.7 1 0 0 1 1 1 0 MCM N-terminal domain CENP-K PF11802.8 EAU93029.1 - 0.85 9.1 3.4 6.8 6.2 1.2 2.1 2 0 0 2 2 2 0 Centromere-associated protein K Shisa PF13908.6 EAU93030.2 - 0.0036 17.6 0.1 0.0048 17.2 0.1 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SPRY PF00622.28 EAU93031.2 - 1.5e-19 70.3 0.0 2.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 SPRY domain CBS PF00571.28 EAU93032.2 - 1.7e-19 70.0 3.7 1.3e-08 35.1 0.1 4.4 4 0 0 4 4 4 4 CBS domain PX PF00787.24 EAU93034.1 - 9.7e-16 57.8 0.0 2.1e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 PX domain T3SSipB PF16535.5 EAU93034.1 - 0.073 13.5 0.8 0.073 13.5 0.8 2.0 2 0 0 2 2 2 0 Type III cell invasion protein SipB Mito_carr PF00153.27 EAU93035.1 - 1.4e-58 194.8 1.1 3.8e-18 65.2 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EAU93035.1 - 1.4 8.0 4.3 2.2 7.4 0.1 2.4 3 0 0 3 3 3 0 Gammaproteobacterial serine protease IF4E PF01652.18 EAU93036.1 - 1.2e-50 171.4 0.0 1.7e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pil1 PF13805.6 EAU93037.1 - 1.9e-45 155.4 1.4 3e-45 154.8 1.4 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 APG6_N PF17675.1 EAU93037.1 - 4.2 7.9 20.5 2.1 8.9 7.9 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region Acetyltransf_1 PF00583.25 EAU93039.2 - 1e-09 38.7 0.0 1.2e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EAU93039.2 - 1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EAU93039.2 - 3.1e-06 27.5 0.0 4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EAU93039.2 - 0.00054 19.9 0.0 0.00084 19.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EAU93039.2 - 0.0018 18.5 0.0 0.0022 18.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EAU93039.2 - 0.0079 16.3 0.0 0.012 15.8 0.0 1.4 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EAU93039.2 - 0.028 13.9 0.1 0.051 13.0 0.1 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase ESSS PF10183.9 EAU93040.1 - 1.2e-11 44.7 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GCV_H PF01597.19 EAU93041.1 - 2.6e-40 137.1 0.0 3e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EAU93041.1 - 1.5e-05 24.9 0.1 2.3e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EAU93041.1 - 0.00012 21.8 0.1 0.0002 21.1 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 EAU93041.1 - 0.12 12.1 0.3 6.6 6.5 0.0 2.1 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.22 EAU93041.1 - 0.13 12.5 1.2 3.1 8.1 0.3 2.4 1 1 1 2 2 2 0 Peptidase family M23 GTP_EFTU PF00009.27 EAU93042.2 - 1.6e-56 190.9 0.1 2.4e-56 190.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EAU93042.2 - 1.4e-25 89.7 0.9 2.1e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EAU93042.2 - 6.6e-16 58.5 1.6 1.5e-15 57.4 1.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EAU93042.2 - 0.00013 22.1 0.1 0.00022 21.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU93042.2 - 0.014 15.3 0.1 0.032 14.1 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EAU93042.2 - 0.027 14.1 0.4 0.052 13.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EAU93042.2 - 0.078 12.7 0.2 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cation_efflux PF01545.21 EAU93048.2 - 6e-47 160.0 1.4 1.2e-46 158.9 1.4 1.5 1 1 0 1 1 1 1 Cation efflux family Ipi1_N PF12333.8 EAU93050.2 - 5.5e-19 68.7 0.1 2.4e-18 66.6 0.0 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Synthase_beta PF11421.8 EAU93050.2 - 7.3 7.4 8.8 2.7 8.7 2.8 3.0 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Cellulase PF00150.18 EAU93051.1 - 5.3e-23 81.8 4.3 7.7e-23 81.3 4.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EAU93051.1 - 0.0053 16.2 1.4 0.053 12.9 0.9 2.6 1 1 1 2 2 2 1 Beta-galactosidase E1_DerP2_DerF2 PF02221.15 EAU93053.1 - 1.5e-21 77.2 0.2 1.8e-21 77.0 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EAU93053.1 - 0.0001 22.7 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 ML-like domain Enolase_C PF00113.22 EAU93053.1 - 0.19 11.0 0.1 0.25 10.5 0.1 1.1 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Tetraspanin PF00335.20 EAU93054.2 - 0.00014 21.7 2.0 0.00014 21.7 2.0 1.6 1 1 0 1 1 1 1 Tetraspanin family Zip PF02535.22 EAU93054.2 - 0.003 16.8 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2070 PF09843.9 EAU93054.2 - 0.02 13.2 4.6 0.026 12.8 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TarH PF02203.15 EAU93054.2 - 0.055 13.4 0.1 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue Bax1-I PF01027.20 EAU93054.2 - 0.35 10.7 8.9 0.18 11.6 6.1 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 GH115_C PF17829.1 EAU93055.2 - 0.0066 16.3 0.0 0.0074 16.1 0.0 1.1 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Ribosomal_L17 PF01196.19 EAU93056.1 - 2.6e-34 118.0 1.9 7.3e-34 116.5 0.1 2.3 2 1 0 2 2 2 1 Ribosomal protein L17 PP-binding PF00550.25 EAU93057.2 - 1.8e-14 53.8 0.1 2.2e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EAU93057.2 - 3e-06 27.4 0.1 4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L13 PF00572.18 EAU93058.1 - 4.4e-11 43.1 0.0 2.2e-09 37.6 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 KH_1 PF00013.29 EAU93059.1 - 8.9e-43 144.0 9.0 1.6e-15 56.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EAU93059.1 - 3e-10 39.8 0.2 0.01 15.7 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 EAU93059.1 - 1.6e-08 34.2 5.4 0.037 13.8 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EAU93059.1 - 3e-05 24.0 3.7 0.11 12.6 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.19 EAU93059.1 - 0.0063 16.2 0.2 0.61 9.8 0.0 2.4 2 0 0 2 2 2 1 dUTPase NUFIP1 PF10453.9 EAU93060.1 - 8.3e-19 67.2 0.2 1.5e-18 66.4 0.2 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1644 PF07800.12 EAU93060.1 - 0.063 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Peptidase_M16 PF00675.20 EAU93061.2 - 2e-10 40.8 0.1 5.3e-09 36.2 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EAU93061.2 - 2.1e-08 34.4 0.0 0.015 15.3 0.0 3.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain M16C_assoc PF08367.11 EAU93061.2 - 0.052 12.7 0.4 9 5.3 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16C associated Exo_endo_phos PF03372.23 EAU93062.2 - 6.9e-25 87.9 0.2 1.1e-24 87.2 0.2 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.20 EAU93063.1 - 1.5e-17 64.4 0.0 2.4e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Gemini_mov PF01708.16 EAU93064.1 - 0.35 10.7 4.4 10 6.0 2.2 2.7 2 0 0 2 2 2 0 Geminivirus putative movement protein Gly-zipper_Omp PF13488.6 EAU93064.1 - 3.2 7.8 5.0 13 5.9 5.0 1.9 1 1 0 1 1 1 0 Glycine zipper Fungal_trans PF04082.18 EAU93065.2 - 6e-09 35.3 0.0 8.9e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UPF0047 PF01894.17 EAU93066.2 - 2.6e-37 127.5 0.1 3e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 p450 PF00067.22 EAU93067.2 - 5.8e-51 173.7 0.0 2.9e-50 171.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EAU93068.2 - 6.4e-10 38.5 0.2 3.6e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ras PF00071.22 EAU93070.2 - 1.2e-54 184.3 0.0 1.4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU93070.2 - 1.6e-21 76.7 0.0 2.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU93070.2 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAU93070.2 - 0.0063 16.1 0.0 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF423 PF04241.15 EAU93072.1 - 0.034 14.4 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Spb1_C PF07780.12 EAU93073.1 - 2.1e-80 269.3 26.0 2.1e-80 269.3 26.0 2.9 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EAU93073.1 - 1e-56 191.8 0.0 1.5e-55 188.0 0.0 2.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EAU93073.1 - 2.8e-49 167.1 4.3 2.8e-49 167.1 4.3 5.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) DHHC PF01529.20 EAU93074.2 - 8.5e-33 113.3 5.0 8.5e-33 113.3 5.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 EAU93074.2 - 0.53 10.2 6.8 0.98 9.4 6.8 1.4 1 0 0 1 1 1 0 Ribosomal L40e family DZR PF12773.7 EAU93074.2 - 0.75 9.9 7.9 1.2 9.2 7.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon SLS PF14611.6 EAU93075.2 - 0.0015 18.4 0.3 0.0036 17.1 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator BCAS2 PF05700.11 EAU93075.2 - 0.21 11.2 6.7 0.8 9.4 1.9 2.6 3 0 0 3 3 3 0 Breast carcinoma amplified sequence 2 (BCAS2) PPR_2 PF13041.6 EAU93077.1 - 4e-31 107.0 0.0 3.7e-08 33.4 0.0 7.5 7 0 0 7 7 7 5 PPR repeat family PPR PF01535.20 EAU93077.1 - 2.2e-18 65.2 0.9 9.5e-09 34.9 0.0 7.4 8 0 0 8 8 8 2 PPR repeat PPR_3 PF13812.6 EAU93077.1 - 1.5e-14 53.8 0.3 5.6e-05 23.1 0.0 6.7 6 1 1 7 7 7 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 EAU93077.1 - 4.7e-12 45.4 0.0 5.8e-05 22.7 0.0 6.2 6 0 0 6 6 6 2 PPR repeat AEP1 PF17049.5 EAU93077.1 - 2.4e-05 23.6 0.0 0.028 13.5 0.0 3.6 3 1 1 4 4 4 2 ATPase expression protein 1 PPR_long PF17177.4 EAU93077.1 - 0.00018 21.0 0.1 0.51 9.7 0.0 3.2 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EAU93077.1 - 0.0015 19.2 6.2 1.5 9.9 0.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat Clathrin PF00637.20 EAU93077.1 - 0.039 13.8 0.1 0.85 9.5 0.2 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS Rad51 PF08423.11 EAU93078.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_35 PF14516.6 EAU93078.1 - 0.12 11.2 0.0 0.44 9.3 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Atg14 PF10186.9 EAU93079.2 - 0.0048 16.0 5.8 0.0048 16.0 5.8 2.0 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 EAU93079.2 - 0.011 15.0 26.2 0.43 9.7 0.8 3.4 3 0 0 3 3 3 0 HAP1 N-terminal conserved region TSC22 PF01166.18 EAU93079.2 - 0.22 11.9 17.3 3.9 7.9 0.0 4.7 5 0 0 5 5 5 0 TSC-22/dip/bun family ATG16 PF08614.11 EAU93079.2 - 0.33 11.1 36.5 0.84 9.8 6.2 4.2 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Aminopep PF10023.9 EAU93079.2 - 0.51 9.7 8.6 0.94 8.8 8.6 1.4 1 0 0 1 1 1 0 Putative aminopeptidase ZapB PF06005.12 EAU93079.2 - 0.7 10.4 32.6 8.2 7.0 8.3 4.9 3 1 1 4 4 4 0 Cell division protein ZapB YabA PF06156.13 EAU93079.2 - 0.72 10.5 19.5 2.7 8.7 0.1 4.4 3 1 0 3 3 2 0 Initiation control protein YabA DivIC PF04977.15 EAU93079.2 - 1 9.2 29.2 5.9 6.7 3.2 6.1 4 1 2 6 6 6 0 Septum formation initiator HAUS-augmin3 PF14932.6 EAU93079.2 - 2.2 7.8 27.5 1.5 8.4 0.2 4.0 3 1 1 4 4 4 0 HAUS augmin-like complex subunit 3 AAA_23 PF13476.6 EAU93079.2 - 3.4 8.1 18.0 0.46 10.9 12.7 2.1 2 0 0 2 2 2 0 AAA domain Arm-DNA-bind_5 PF17293.2 EAU93079.2 - 7.1 7.2 7.3 25 5.4 1.7 3.2 3 0 0 3 3 3 0 Arm DNA-binding domain Jnk-SapK_ap_N PF09744.9 EAU93079.2 - 7.4 6.8 28.5 0.98 9.6 0.0 4.0 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 EAU93079.2 - 7.9 6.5 8.5 0.51 10.4 2.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Nefa_Nip30_N PF10187.9 EAU93082.1 - 5e-31 107.2 17.6 5e-31 107.2 17.6 2.1 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 EAU93082.1 - 0.37 10.4 15.4 0.46 10.1 15.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Es2 PF09751.9 EAU93083.1 - 1.4e-93 315.0 14.8 1.9e-93 314.6 14.8 1.2 1 0 0 1 1 1 1 Nuclear protein Es2 NUDE_C PF04880.13 EAU93084.2 - 1.4e-11 45.2 18.9 1.4e-11 45.2 18.9 3.1 2 2 1 3 3 3 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 EAU93084.2 - 0.00067 20.5 12.3 0.00067 20.5 12.3 3.6 1 1 2 3 3 3 1 cGMP-dependent protein kinase interacting domain DUF2353 PF09789.9 EAU93084.2 - 0.018 14.4 26.7 0.031 13.7 16.1 2.7 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) HIP1_clath_bdg PF16515.5 EAU93084.2 - 0.022 15.4 30.9 0.39 11.4 9.6 3.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 EAU93084.2 - 0.025 14.0 33.0 0.25 10.7 12.4 2.9 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ERM PF00769.19 EAU93084.2 - 0.026 14.4 38.7 0.017 15.0 22.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ZapB PF06005.12 EAU93084.2 - 0.038 14.4 2.5 0.038 14.4 2.5 3.8 1 1 2 3 3 3 0 Cell division protein ZapB ADIP PF11559.8 EAU93084.2 - 0.23 11.5 32.6 0.056 13.5 5.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 EAU93084.2 - 0.39 10.8 36.2 2.4 8.2 9.7 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EAU93084.2 - 0.44 11.1 43.9 0.055 14.0 12.1 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region Fez1 PF06818.15 EAU93084.2 - 0.69 10.3 32.3 5.1 7.5 18.0 2.5 1 1 2 3 3 3 0 Fez1 Spc7 PF08317.11 EAU93084.2 - 1 8.2 32.6 0.13 11.1 9.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 EAU93084.2 - 1.1 7.8 21.5 0.16 10.6 7.4 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Myb_DNA-bind_3 PF12776.7 EAU93084.2 - 1.2 10.1 6.3 0.48 11.4 2.0 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Tup_N PF08581.10 EAU93084.2 - 1.5 9.2 24.5 0.45 10.9 7.6 3.9 1 1 2 3 3 3 0 Tup N-terminal DUF4472 PF14739.6 EAU93084.2 - 1.6 9.5 25.2 0.55 11.0 7.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF4407 PF14362.6 EAU93084.2 - 1.9 7.8 22.2 0.029 13.7 7.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 EAU93084.2 - 2.9 7.1 28.9 2.4 7.4 8.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 EAU93084.2 - 6.3 7.4 24.8 0.19 12.3 5.5 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Leu_zip PF15294.6 EAU93084.2 - 7.5 6.0 29.0 1.2 8.6 11.9 2.5 1 1 1 2 2 2 0 Leucine zipper Chibby PF14645.6 EAU93084.2 - 9.4 6.7 20.1 12 6.4 2.6 4.1 1 1 3 4 4 4 0 Chibby family EXOSC1 PF10447.9 EAU93085.1 - 7.2e-19 68.4 1.6 6.5e-14 52.5 0.6 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EAU93085.1 - 0.0025 17.6 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region 2-oxoacid_dh PF00198.23 EAU93086.1 - 3.6e-82 275.3 0.0 4.5e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAU93086.1 - 1.9e-20 72.4 2.1 2.3e-20 72.2 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EAU93086.1 - 1.5e-14 54.1 0.4 3.4e-14 52.9 0.4 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EAU93086.1 - 0.057 13.3 0.2 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like ERM PF00769.19 EAU93087.2 - 0.00054 19.9 31.1 0.011 15.5 5.2 3.4 3 0 0 3 3 3 3 Ezrin/radixin/moesin family DUF5344 PF17279.2 EAU93087.2 - 0.0071 16.9 1.5 0.0071 16.9 1.5 3.0 2 1 1 3 3 2 1 Family of unknown function (DUF5344) THOC7 PF05615.13 EAU93087.2 - 0.018 15.3 7.8 0.018 15.3 7.8 4.1 3 1 0 4 4 4 0 Tho complex subunit 7 PRKG1_interact PF15898.5 EAU93087.2 - 0.031 15.2 11.5 0.031 15.2 11.5 4.0 2 1 2 4 4 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 EAU93087.2 - 0.031 14.8 42.1 0.48 10.9 8.9 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF5082 PF16888.5 EAU93087.2 - 0.035 14.4 21.4 0.72 10.1 1.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) ZapB PF06005.12 EAU93087.2 - 0.069 13.6 39.0 0.67 10.4 8.2 3.6 2 1 1 3 3 3 0 Cell division protein ZapB APC_N_CC PF16689.5 EAU93087.2 - 0.25 11.5 10.3 3.6 7.7 1.8 3.4 3 1 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain CENP-F_leu_zip PF10473.9 EAU93087.2 - 0.31 11.1 32.9 0.91 9.5 6.0 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 EAU93087.2 - 0.44 10.8 27.7 0.67 10.2 13.1 3.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MIP-T3_C PF17749.1 EAU93087.2 - 0.46 10.4 16.8 0.3 11.0 4.7 3.1 2 1 1 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region YabA PF06156.13 EAU93087.2 - 0.54 10.9 29.1 1 10.1 3.8 3.9 3 1 1 4 4 3 0 Initiation control protein YabA KASH_CCD PF14662.6 EAU93087.2 - 1 9.2 35.6 4.3 7.1 13.6 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EAU93087.2 - 1.3 9.1 39.4 1 9.4 8.5 3.4 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 EAU93087.2 - 1.4 8.6 29.6 1.9 8.2 2.6 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 EAU93087.2 - 1.5 9.5 33.6 9.3 6.9 14.8 3.7 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4200 PF13863.6 EAU93087.2 - 1.5 9.2 29.6 3.6 8.0 6.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF3584 PF12128.8 EAU93087.2 - 1.7 6.1 31.1 2.8 5.4 31.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) COG5 PF10392.9 EAU93087.2 - 1.9 8.7 17.4 0.093 12.9 5.8 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 ADIP PF11559.8 EAU93087.2 - 2.3 8.3 35.3 1.5 8.9 8.7 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EAU93087.2 - 2.4 6.9 32.5 12 4.7 11.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 EAU93087.2 - 3.2 7.6 32.9 2.2 8.1 6.1 3.7 3 1 0 3 3 3 0 Septum formation initiator UPF0449 PF15136.6 EAU93087.2 - 4.5 7.8 22.8 4.7 7.7 2.0 3.9 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 MAD PF05557.13 EAU93087.2 - 4.6 5.5 34.8 3.2 6.0 19.6 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.8 EAU93087.2 - 4.9 7.4 33.5 3 8.1 5.2 3.7 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 EAU93087.2 - 6.3 7.2 32.1 0.17 12.3 6.9 2.8 2 1 0 2 2 2 0 Fez1 Tho2 PF11262.8 EAU93087.2 - 6.9 5.8 18.9 0.94 8.6 4.4 2.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF724 PF05266.14 EAU93087.2 - 9.6 6.0 26.3 1 9.1 4.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF2263 PF10021.9 EAU93088.1 - 5e-28 98.3 0.0 8.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF2263 PF10021.9 EAU93089.1 - 9.2e-44 149.4 0.1 2.3e-43 148.0 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) BTB PF00651.31 EAU93091.2 - 0.062 13.5 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Ribosomal_S17_N PF16205.5 EAU93093.1 - 2.2e-32 111.2 0.6 3.9e-32 110.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EAU93093.1 - 2.7e-27 94.7 1.2 2.7e-27 94.7 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 DNA_ligase_A_M PF01068.21 EAU93094.2 - 3.5e-66 222.7 0.1 7e-66 221.8 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EAU93094.2 - 5.1e-30 105.1 2.2 5.5e-30 104.9 0.5 2.0 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EAU93094.2 - 3.7e-26 91.6 0.0 1e-25 90.2 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EAU93094.2 - 0.00083 19.7 0.0 0.0021 18.4 0.0 1.7 2 0 0 2 2 2 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EAU93094.2 - 0.014 15.4 0.1 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain ORC6 PF05460.13 EAU93094.2 - 0.13 11.5 11.2 0.24 10.7 11.2 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MPC PF03650.13 EAU93095.1 - 4.1e-35 120.3 0.1 5.1e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers NUDIX PF00293.28 EAU93097.1 - 2.7e-27 95.4 0.0 3.6e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Rad21_Rec8_N PF04825.13 EAU93098.2 - 3e-18 66.0 0.0 1e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EAU93098.2 - 0.0047 16.2 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3292 PF11696.8 EAU93099.2 - 1.2e-09 37.2 0.7 4.6e-05 22.0 0.5 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF3292) GRAM PF02893.20 EAU93099.2 - 5.5e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.10 EAU93099.2 - 0.02 14.7 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal INCENP_ARK-bind PF03941.15 EAU93100.2 - 1.3e-20 73.1 1.6 6.8e-20 70.8 1.6 2.4 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Sigma70_r1_2 PF00140.20 EAU93100.2 - 0.028 14.4 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 MotY_N PF18393.1 EAU93100.2 - 1.2 9.3 4.6 5.6 7.1 0.0 2.8 2 0 0 2 2 2 0 MotY N-terminal domain DCP2 PF05026.13 EAU93101.2 - 3.4e-32 110.6 1.9 5.7e-32 109.9 1.9 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EAU93101.2 - 4.8e-12 46.1 0.0 8.8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Pribosyltran_N PF13793.6 EAU93102.2 - 8.6e-46 154.6 0.5 2.6e-44 149.9 0.1 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EAU93102.2 - 3.7e-40 137.9 3.1 3.3e-34 118.5 0.3 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EAU93102.2 - 1.9e-14 53.5 2.0 2.1e-14 53.3 0.6 1.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EAU93102.2 - 0.039 13.4 0.1 0.07 12.6 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase IncD PF17628.2 EAU93102.2 - 0.04 13.7 0.3 0.086 12.6 0.3 1.5 1 0 0 1 1 1 0 Inclusion membrane protein D DUF848 PF05852.11 EAU93102.2 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Pkinase PF00069.25 EAU93103.2 - 8.8e-51 172.8 0.0 2.7e-49 167.9 0.0 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93103.2 - 1.2e-23 83.8 0.0 2.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_Gp23 PF10669.9 EAU93103.2 - 1.2 9.5 5.1 2.1 8.7 5.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) zf-CHCC PF10276.9 EAU93104.2 - 3.1e-17 62.3 2.4 4.5e-17 61.8 2.4 1.2 1 0 0 1 1 1 1 Zinc-finger domain AAA_2 PF07724.14 EAU93105.1 - 1.3e-51 175.1 0.0 6.2e-47 159.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EAU93105.1 - 1.2e-32 111.9 2.3 1.2e-32 111.9 2.3 3.2 2 1 0 2 2 2 1 AAA lid domain AAA PF00004.29 EAU93105.1 - 1.2e-25 90.4 0.0 3.9e-13 50.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EAU93105.1 - 6.1e-23 80.7 0.1 3.5e-22 78.3 0.1 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EAU93105.1 - 6e-19 67.9 3.7 3.4e-12 46.3 0.5 4.1 4 0 0 4 4 3 3 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EAU93105.1 - 9.9e-15 54.7 0.0 6.8e-08 32.6 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU93105.1 - 3.8e-12 46.9 0.5 9.2e-06 26.1 0.0 4.6 3 1 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EAU93105.1 - 3.5e-09 36.6 0.0 5.6e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EAU93105.1 - 1.8e-07 31.5 0.1 0.048 13.9 0.0 4.1 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EAU93105.1 - 5e-07 29.6 0.0 0.0017 18.1 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EAU93105.1 - 5.5e-07 29.2 0.0 0.0014 18.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EAU93105.1 - 6e-06 25.7 0.5 0.16 11.1 0.0 3.2 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_24 PF13479.6 EAU93105.1 - 8.8e-06 25.6 0.0 0.013 15.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EAU93105.1 - 4.2e-05 23.0 0.0 0.071 12.5 0.0 3.7 3 1 0 3 3 2 1 Bacterial TniB protein RNA_helicase PF00910.22 EAU93105.1 - 0.00012 22.4 0.0 0.67 10.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 EAU93105.1 - 0.00015 21.3 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 EAU93105.1 - 0.00024 20.9 0.1 1.6 8.5 0.0 3.8 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain Laminin_II PF06009.12 EAU93105.1 - 0.00036 20.5 2.4 0.001 19.1 2.4 1.8 1 0 0 1 1 1 1 Laminin Domain II AAA_33 PF13671.6 EAU93105.1 - 0.00039 20.6 0.0 0.41 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EAU93105.1 - 0.00059 19.8 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EAU93105.1 - 0.0007 20.1 0.9 0.41 11.2 0.0 3.4 3 1 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EAU93105.1 - 0.0011 18.3 0.3 0.26 10.5 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.6 EAU93105.1 - 0.0012 18.9 0.1 0.27 11.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 EAU93105.1 - 0.0025 17.3 0.1 0.72 9.3 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_30 PF13604.6 EAU93105.1 - 0.0043 16.8 0.0 3.8 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EAU93105.1 - 0.0072 16.4 0.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 Torsin AAA_3 PF07726.11 EAU93105.1 - 0.011 15.6 0.0 41 4.0 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EAU93105.1 - 0.011 15.7 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EAU93105.1 - 0.02 15.1 0.0 2.5 8.4 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 EAU93105.1 - 0.024 14.7 0.0 1.9 8.5 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EAU93105.1 - 0.025 14.9 0.1 4.8 7.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 EAU93105.1 - 0.031 13.3 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein CbiA PF01656.23 EAU93105.1 - 0.079 13.0 0.2 14 5.7 0.0 3.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.22 EAU93105.1 - 0.11 12.1 0.0 19 4.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.6 EAU93105.1 - 0.12 12.5 0.0 32 4.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EAU93105.1 - 0.13 12.2 0.3 5.1 7.0 0.0 3.2 3 0 0 3 3 3 0 NTPase DUF4407 PF14362.6 EAU93105.1 - 0.13 11.6 10.4 0.27 10.6 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 EAU93105.1 - 0.14 11.5 12.7 0.99 8.7 12.8 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 EAU93105.1 - 0.16 12.5 1.9 14 6.2 0.0 3.4 3 0 0 3 3 3 0 ABC transporter ATPase_2 PF01637.18 EAU93105.1 - 0.18 11.7 6.6 13 5.6 0.1 4.5 3 2 2 5 5 5 0 ATPase domain predominantly from Archaea Exonuc_VII_L PF02601.15 EAU93105.1 - 0.2 11.2 4.7 0.57 9.7 4.7 1.8 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EAU93105.1 - 0.28 10.0 12.3 0.54 9.1 12.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 EAU93105.1 - 0.74 9.6 10.9 1.8 8.3 10.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ATPase PF06745.13 EAU93105.1 - 1 8.7 5.6 2.9 7.2 0.0 3.7 4 1 0 4 4 3 0 KaiC AAA_25 PF13481.6 EAU93105.1 - 1 8.9 5.4 13 5.3 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EAU93105.1 - 1 9.5 7.6 3.9 7.7 0.0 3.8 4 0 0 4 4 3 0 AAA domain Uds1 PF15456.6 EAU93105.1 - 1.1 9.4 10.6 3.9 7.6 10.6 1.9 1 0 0 1 1 1 0 Up-regulated During Septation AAA_23 PF13476.6 EAU93105.1 - 5.5 7.4 22.4 12 6.3 0.0 4.1 3 1 0 3 3 2 0 AAA domain TMPIT PF07851.13 EAU93105.1 - 6.3 5.9 6.6 11 5.2 6.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Nup54 PF13874.6 EAU93105.1 - 6.5 6.9 11.7 4.5 7.4 8.7 2.4 2 1 0 2 2 1 0 Nucleoporin complex subunit 54 Mod_r PF07200.13 EAU93105.1 - 6.9 6.8 13.5 1.1 9.3 9.0 2.1 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.9 EAU93105.1 - 8.4 5.4 10.7 17 4.4 10.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EMP24_GP25L PF01105.24 EAU93106.2 - 0.00082 19.4 10.8 0.14 12.1 2.0 3.1 2 1 1 3 3 3 1 emp24/gp25L/p24 family/GOLD Tox-GHH PF15636.6 EAU93106.2 - 0.0011 18.9 2.8 0.0028 17.6 2.8 1.7 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin ZapB PF06005.12 EAU93106.2 - 0.0024 18.3 12.9 0.069 13.6 0.6 3.0 3 0 0 3 3 2 2 Cell division protein ZapB DUF2353 PF09789.9 EAU93106.2 - 0.0049 16.3 11.3 0.0051 16.2 9.9 1.6 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) DUF3584 PF12128.8 EAU93106.2 - 0.017 12.7 14.7 0.029 11.9 13.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ATG16 PF08614.11 EAU93106.2 - 0.026 14.7 13.0 0.054 13.7 13.0 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 EAU93106.2 - 0.032 12.2 6.9 0.043 11.7 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.13 EAU93106.2 - 0.038 14.4 10.4 0.26 11.7 1.6 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DASH_Dam1 PF08653.10 EAU93106.2 - 0.077 12.8 0.3 0.36 10.7 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Prefoldin_2 PF01920.20 EAU93106.2 - 0.087 12.8 0.7 0.087 12.8 0.7 3.1 3 1 0 3 3 3 0 Prefoldin subunit BicD PF09730.9 EAU93106.2 - 0.11 10.9 14.6 0.0078 14.7 7.9 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D Exonuc_VII_L PF02601.15 EAU93106.2 - 0.13 11.8 10.0 0.23 11.0 10.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit US2 PF02476.15 EAU93106.2 - 0.14 12.8 1.8 0.93 10.2 0.8 2.4 3 0 0 3 3 2 0 US2 family TPR_MLP1_2 PF07926.12 EAU93106.2 - 0.18 11.9 17.0 0.078 13.0 13.6 2.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 EAU93106.2 - 0.21 11.8 9.9 0.17 12.1 6.2 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EAU93106.2 - 0.22 11.8 10.6 0.58 10.5 0.7 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EAU93106.2 - 0.29 11.6 2.8 14 6.3 0.6 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KASH_CCD PF14662.6 EAU93106.2 - 0.34 10.7 14.6 0.056 13.3 9.7 2.1 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EAU93106.2 - 0.38 9.6 14.8 0.68 8.8 13.0 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4472 PF14739.6 EAU93106.2 - 0.53 11.0 15.7 0.86 10.4 2.1 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4472) SOGA PF11365.8 EAU93106.2 - 0.55 11.4 11.4 0.33 12.1 2.3 2.8 2 1 0 2 2 2 0 Protein SOGA DUF948 PF06103.11 EAU93106.2 - 0.6 10.4 3.2 0.9 9.8 0.2 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 EAU93106.2 - 0.79 9.9 15.8 3.1 8.0 15.5 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 P4Ha_N PF08336.11 EAU93106.2 - 0.85 9.6 6.9 0.12 12.4 0.7 2.4 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region GAS PF13851.6 EAU93106.2 - 1.2 8.4 20.7 1.7 8.0 17.4 2.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 EAU93106.2 - 1.5 8.1 9.9 2.2 7.5 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 EAU93106.2 - 3.3 6.5 6.7 4.4 6.1 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 EAU93106.2 - 3.3 8.4 14.1 8.3 7.1 3.1 2.9 2 1 1 3 3 3 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 EAU93106.2 - 3.9 7.0 14.0 0.77 9.3 9.1 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Laminin_II PF06009.12 EAU93106.2 - 4.2 7.4 10.0 3.4 7.7 3.7 2.8 2 1 1 3 3 3 0 Laminin Domain II SlyX PF04102.12 EAU93106.2 - 5.1 7.8 7.1 2.9 8.6 0.7 3.2 2 1 0 3 3 3 0 SlyX Spc24 PF08286.11 EAU93106.2 - 6.6 7.0 12.7 17 5.7 3.2 2.9 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 CLZ PF16526.5 EAU93106.2 - 6.9 7.1 12.8 5.9 7.3 5.7 3.6 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Plk4_PB2 PF18409.1 EAU93106.2 - 6.9 7.4 7.9 1 10.1 0.7 2.5 2 1 1 3 3 2 0 Polo-like Kinase 4 Polo Box 2 Vac_Fusion PF02346.16 EAU93106.2 - 7.2 6.3 9.2 0.79 9.4 2.5 2.8 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 TSC22 PF01166.18 EAU93106.2 - 8.1 6.8 7.2 1.9 8.8 0.5 3.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Mg_trans_NIPA PF05653.14 EAU93108.2 - 1.7e-19 70.0 15.1 7.4e-10 38.4 3.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DENN PF02141.21 EAU93109.1 - 6.5e-19 68.6 0.0 1.4e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain ADIP PF11559.8 EAU93109.1 - 0.0023 18.0 10.2 0.0023 18.0 10.2 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding YabA PF06156.13 EAU93109.1 - 0.28 11.8 7.8 11 6.7 2.5 3.1 2 0 0 2 2 2 0 Initiation control protein YabA YadA_head PF05658.14 EAU93109.1 - 0.63 10.5 3.0 15 6.1 1.9 2.6 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin IFT20 PF14931.6 EAU93109.1 - 0.64 10.2 7.8 1.5 9.0 7.8 1.7 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 FapA PF03961.13 EAU93109.1 - 1.6 7.3 5.6 3.2 6.3 5.6 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A SOGA PF11365.8 EAU93109.1 - 2.8 9.1 11.6 9.5 7.4 9.5 2.8 1 1 1 2 2 2 0 Protein SOGA VPS13_mid_rpt PF16910.5 EAU93110.2 - 9.4e-98 326.3 10.4 1.9e-93 312.3 1.8 4.8 3 1 1 4 4 4 3 Repeating coiled region of VPS13 VPS13 PF16908.5 EAU93110.2 - 5e-79 265.4 6.1 3.4e-75 252.9 0.2 3.6 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EAU93110.2 - 1.3e-70 236.8 3.7 6.9e-66 221.4 0.1 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EAU93110.2 - 1.5e-62 211.4 0.0 2.9e-57 194.1 0.0 3.9 3 1 1 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EAU93110.2 - 4.3e-30 104.2 0.4 1.7e-29 102.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EAU93110.2 - 5.3e-11 42.7 0.0 6.3e-09 36.1 0.0 3.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ELO PF01151.18 EAU93111.2 - 1.9e-59 201.2 20.1 2.2e-59 201.0 20.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UPF0242 PF06785.11 EAU93111.2 - 0.59 10.2 2.5 27 4.8 1.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2231 PF09990.9 EAU93111.2 - 0.81 10.2 8.4 0.66 10.4 0.3 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) RasGAP PF00616.19 EAU93112.2 - 1.9e-29 102.9 0.0 5.8e-23 81.7 0.0 2.2 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EAU93112.2 - 1.5e-06 28.4 0.0 3.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain PI3K_C2 PF00792.24 EAU93112.2 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase C2 Adaptin_N PF01602.20 EAU93113.2 - 1.6e-109 366.9 5.5 2.5e-109 366.2 5.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EAU93113.2 - 1.5e-37 128.2 0.0 3e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EAU93113.2 - 1.5e-15 57.4 0.1 2.7e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 EAU93113.2 - 0.014 15.6 0.2 1.6 9.2 0.1 3.8 4 0 0 4 4 4 0 HEAT repeat RTP1_C1 PF10363.9 EAU93113.2 - 0.016 15.4 0.7 0.046 13.9 0.7 1.7 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EAU93116.2 - 4.2e-36 119.9 10.1 0.0042 17.2 0.1 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 EAU93116.2 - 4.6e-31 107.1 9.2 9e-11 42.0 0.0 7.5 3 3 4 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 EAU93116.2 - 1.3e-08 35.2 9.6 0.19 12.3 0.0 8.3 8 2 1 9 9 9 2 HEAT-like repeat Arm PF00514.23 EAU93116.2 - 1.5e-06 28.0 1.6 0.62 10.2 0.0 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EAU93116.2 - 3.8e-05 23.8 0.7 1 9.4 0.0 5.0 3 2 3 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EAU93116.2 - 0.16 12.7 2.0 39 5.3 0.0 5.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Aldose_epim PF01263.20 EAU93117.1 - 4.3e-32 111.6 0.0 4.9e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase EamA PF00892.20 EAU93120.2 - 1.1 9.4 37.5 0.074 13.2 16.8 4.1 3 1 0 3 3 3 0 EamA-like transporter family Metallophos PF00149.28 EAU93121.2 - 1.3e-38 133.6 0.0 5.8e-38 131.4 0.0 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EAU93121.2 - 1.8e-10 41.1 0.7 3.5e-10 40.1 0.7 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain ICE2 PF08426.10 EAU93122.2 - 2.6e-32 112.4 16.9 1.3e-18 67.4 5.5 2.9 1 1 1 2 2 2 2 ICE2 Apq12 PF12716.7 EAU93122.2 - 0.029 14.3 3.4 0.029 14.3 3.4 3.1 3 0 0 3 3 3 0 Nuclear pore assembly and biogenesis SNAP PF14938.6 EAU93124.1 - 1.6e-105 352.6 17.9 1.8e-105 352.4 17.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EAU93124.1 - 0.00071 19.8 16.0 0.24 11.7 4.3 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU93124.1 - 0.0014 18.6 7.3 0.057 13.5 0.1 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 EAU93124.1 - 0.0053 16.6 0.5 0.036 14.0 0.1 2.4 2 1 0 2 2 2 1 Region in Clathrin and VPS Spatacsin_C PF14649.6 EAU93124.1 - 0.025 13.7 4.9 0.069 12.3 3.2 2.0 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_6 PF13174.6 EAU93124.1 - 0.075 13.7 13.8 5.7 7.8 0.1 5.8 4 2 2 6 6 5 0 Tetratricopeptide repeat DUF1283 PF06932.11 EAU93124.1 - 0.39 11.0 2.7 1.1 9.5 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) TPR_14 PF13428.6 EAU93124.1 - 0.81 10.7 0.0 0.81 10.7 0.0 4.9 5 1 2 7 7 5 0 Tetratricopeptide repeat NSF PF02071.20 EAU93124.1 - 1.7 9.8 14.0 3.4 8.8 0.1 6.2 7 0 0 7 7 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_1 PF00515.28 EAU93124.1 - 2.3 8.2 10.3 1.9 8.5 0.3 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EAU93124.1 - 4.9 6.9 9.5 2.6 7.8 0.1 4.1 4 1 1 5 5 5 0 TPR repeat DUF2235 PF09994.9 EAU93126.2 - 7.4e-79 265.1 0.1 9.6e-79 264.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MFS_1 PF07690.16 EAU93127.2 - 2e-20 73.1 36.1 3e-13 49.4 19.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Galactosyl_T PF01762.21 EAU93132.2 - 1.5e-08 34.7 0.0 0.00063 19.6 0.0 2.6 2 1 0 2 2 2 2 Galactosyltransferase GST_N_3 PF13417.6 EAU93133.1 - 4.6e-12 46.2 0.1 9.1e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EAU93133.1 - 5.2e-09 36.3 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EAU93133.1 - 1.1e-07 32.1 0.0 2.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EAU93133.1 - 4.6e-06 26.6 0.0 1.2e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU93133.1 - 0.00018 21.6 0.1 0.00062 19.9 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EAU93133.1 - 0.0025 18.0 0.0 0.019 15.1 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EAU93133.1 - 0.18 12.4 0.0 0.45 11.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain O-FucT PF10250.9 EAU93133.1 - 0.18 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase SGS PF05002.15 EAU93134.1 - 1.7e-34 117.8 3.5 2.5e-34 117.2 3.5 1.2 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EAU93134.1 - 1.9e-07 32.0 0.0 3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 CS domain DHFR_1 PF00186.19 EAU93135.2 - 3.9e-23 81.9 0.1 2.6e-20 72.7 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase MoaE PF02391.17 EAU93137.1 - 3.5e-41 140.0 0.0 4.3e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Rieske PF00355.26 EAU93138.2 - 7.9e-12 45.0 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EAU93138.2 - 2.2e-10 40.8 1.9 6.8e-10 39.3 1.9 1.8 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region DUF4149 PF13664.6 EAU93139.2 - 2.8e-24 85.4 4.4 2.8e-24 85.4 4.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 EAU93139.2 - 0.0013 19.1 1.6 0.0018 18.6 1.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF3040 PF11239.8 EAU93139.2 - 0.33 11.2 2.5 23 5.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) LRR_9 PF14580.6 EAU93140.1 - 9.4e-65 217.4 2.0 1e-64 217.2 1.3 1.3 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EAU93140.1 - 2.7e-09 36.6 6.1 9.5e-09 34.9 6.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EAU93140.1 - 3.1e-08 33.8 11.4 2.4e-05 24.6 6.3 3.9 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) Syja_N PF02383.18 EAU93141.1 - 4.6e-89 298.9 0.0 8.2e-89 298.1 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain NAP PF00956.18 EAU93142.1 - 2.9e-26 92.3 8.5 2.9e-26 92.3 8.5 3.0 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) PH_4 PF15404.6 EAU93142.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Polysacc_deac_1 PF01522.21 EAU93143.2 - 7.4e-26 90.5 0.0 1.3e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DASH_Dad2 PF08654.10 EAU93143.2 - 0.079 13.4 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 Pertussis_S2S3 PF02918.15 EAU93144.2 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Pkinase PF00069.25 EAU93145.2 - 1.4e-59 201.6 0.0 1.9e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93145.2 - 5.5e-40 137.3 0.0 8.6e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU93145.2 - 1.2e-08 34.7 0.0 1.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EAU93145.2 - 0.011 15.1 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EAU93145.2 - 0.015 14.1 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Ras_bdg_2 PF14847.6 EAU93145.2 - 0.082 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras-binding domain of Byr2 CLTH PF10607.9 EAU93146.1 - 6.8e-34 116.9 0.0 8.6e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EAU93146.1 - 7.8e-06 25.7 0.3 1.7e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 LisH FPRL1_inhibitor PF16104.5 EAU93146.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 2 0 0 2 2 2 0 Formyl peptide receptor-like 1 inhibitory protein Rrp15p PF07890.12 EAU93147.1 - 5.8e-29 101.1 5.9 5.8e-29 101.1 5.9 2.1 2 0 0 2 2 2 1 Rrp15p PI3K_1B_p101 PF10486.9 EAU93147.1 - 0.19 9.5 7.1 0.26 9.0 7.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DIL PF01843.19 EAU93148.1 - 1e-27 96.4 0.1 2e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.6 EAU93148.1 - 1.8e-06 28.3 0.2 7.9e-05 23.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAU93148.1 - 9.6e-06 26.1 0.0 2.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EAU93148.1 - 3.2e-05 24.0 0.2 0.0027 18.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EAU93148.1 - 0.002 18.5 0.9 0.2 12.1 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EAU93148.1 - 0.0024 18.1 0.0 0.0085 16.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Rhomboid PF01694.22 EAU93149.2 - 3.6e-35 121.2 18.6 5.8e-35 120.5 13.9 2.3 3 0 0 3 3 3 2 Rhomboid family Cas1_AcylT PF07779.12 EAU93150.2 - 8e-124 414.1 12.0 1.2e-123 413.5 12.0 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 EAU93150.2 - 0.00046 20.0 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Cut8 PF08559.10 EAU93151.2 - 1e-18 67.8 1.1 9e-18 64.8 1.1 2.3 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein PPR_2 PF13041.6 EAU93152.1 - 0.21 11.8 0.0 29 4.9 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family Mito_carr PF00153.27 EAU93153.2 - 1.2e-35 121.3 0.4 4.6e-13 48.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LapA_dom PF06305.11 EAU93153.2 - 0.11 12.3 0.4 9.3 6.1 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MHC2-interact PF09307.10 EAU93154.2 - 0.19 11.7 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting Nucleoporin_N PF08801.11 EAU93155.2 - 2.8e-65 220.7 0.1 4.7e-65 220.0 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EAU93155.2 - 1.1e-39 136.7 1.2 1.8e-39 136.0 1.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Transposase_22 PF02994.14 EAU93155.2 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 L1 transposable element RBD-like domain Pkinase PF00069.25 EAU93156.2 - 6.6e-63 212.5 0.0 8.4e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93156.2 - 3.7e-42 144.4 0.0 5.3e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU93156.2 - 1.2e-08 34.7 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EAU93156.2 - 0.00044 19.1 0.0 0.00094 18.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EAU93156.2 - 0.0024 17.8 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EAU93156.2 - 0.024 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EAU93156.2 - 0.048 13.3 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EAU93156.2 - 0.1 11.5 0.1 0.31 9.9 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain NAD_binding_6 PF08030.12 EAU93157.1 - 3.4e-25 89.0 0.0 7.1e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EAU93157.1 - 1.1e-20 73.7 0.0 2.2e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EAU93157.1 - 2.4e-19 69.7 10.9 2.4e-19 69.7 10.9 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EAU93157.1 - 0.0015 19.1 0.0 0.049 14.3 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Ntox3 PF15536.6 EAU93157.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 3 Coatomer_b_Cpla PF14806.6 EAU93157.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform FAD_binding_6 PF00970.24 EAU93157.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain HORMA PF02301.18 EAU93158.2 - 4.9e-17 62.2 0.1 9e-17 61.4 0.1 1.4 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EAU93158.2 - 0.038 14.0 0.0 0.074 13.0 0.0 1.5 1 1 0 1 1 1 0 Autophagy-related protein 101 Phage_holin_1 PF04531.13 EAU93158.2 - 0.082 13.5 0.2 3.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin Proton_antipo_M PF00361.20 EAU93158.2 - 0.09 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Proton-conducting membrane transporter WD40 PF00400.32 EAU93159.2 - 3.2e-44 148.0 12.7 4.4e-08 33.6 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EAU93159.2 - 1e-30 106.6 0.0 2.2e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EAU93159.2 - 1.7e-09 37.8 0.0 0.0058 16.9 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EAU93159.2 - 0.00038 20.3 0.1 0.0068 16.3 0.0 2.4 2 0 0 2 2 2 1 LisH Nup160 PF11715.8 EAU93159.2 - 0.11 11.1 2.6 0.53 8.9 0.0 2.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 RsdA_SigD_bd PF16751.5 EAU93161.2 - 0.079 13.2 0.3 18 5.7 0.3 2.3 2 0 0 2 2 2 0 Anti-sigma-D factor RsdA to sigma factor binding region TMEM171 PF15471.6 EAU93162.2 - 3 6.7 6.4 7.1 5.5 6.4 1.5 1 0 0 1 1 1 0 Transmembrane protein family 171 DcuC PF03606.15 EAU93163.1 - 0.099 11.1 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier MGC-24 PF05283.11 EAU93163.1 - 2.8 8.4 6.0 0.61 10.5 1.2 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin OAD_gamma PF04277.13 EAU93163.1 - 3.1 8.5 0.0 3.1 8.5 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Meth_synt_2 PF01717.18 EAU93164.2 - 8.4e-20 71.3 0.0 4.5e-14 52.5 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EAU93164.2 - 0.0017 18.0 0.0 0.1 12.1 0.0 2.7 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.18 EAU93165.1 - 3.9e-75 251.7 4.1 5.6e-75 251.1 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e FA_desaturase PF00487.24 EAU93166.1 - 4.7e-25 88.9 27.2 7.9e-25 88.1 27.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EAU93166.1 - 9e-08 32.2 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pal1 PF08316.11 EAU93167.1 - 2.1e-15 57.7 0.3 2.1e-15 57.7 0.3 2.2 3 0 0 3 3 3 1 Pal1 cell morphology protein His_biosynth PF00977.21 EAU93168.1 - 4.4e-42 144.1 0.1 3.7e-41 141.1 0.1 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EAU93168.1 - 1.8e-22 80.0 0.0 2.9e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EAU93168.1 - 8.9e-08 32.0 0.0 1.7e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 EAU93168.1 - 1.4e-07 31.5 0.0 2.1e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 EAU93168.1 - 0.0048 16.7 0.1 0.25 11.1 0.0 2.5 3 0 0 3 3 3 1 Peptidase C26 Peptidase_S51 PF03575.17 EAU93168.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 2-Hacid_dh_C PF02826.19 EAU93169.1 - 5.3e-53 179.0 0.0 9.8e-53 178.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EAU93169.1 - 8.7e-35 119.3 0.0 1.3e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EAU93169.1 - 0.001 19.3 0.1 0.0033 17.6 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EAU93169.1 - 0.0085 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Nitro_FeMo-Co PF02579.17 EAU93169.1 - 0.012 15.9 0.0 1.3 9.4 0.0 2.9 2 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DUF2597 PF10772.9 EAU93169.1 - 0.045 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Peptidase_M15_4 PF13539.6 EAU93169.1 - 0.079 13.5 0.0 2 9.0 0.0 2.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Rad51 PF08423.11 EAU93170.1 - 2.2e-125 417.1 0.0 2.7e-125 416.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EAU93170.1 - 1.1e-09 38.2 0.0 1.6e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EAU93170.1 - 1.2e-08 34.8 0.0 1.6e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EAU93170.1 - 1e-05 26.0 0.9 1e-05 26.0 0.9 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain ATPase PF06745.13 EAU93170.1 - 3.2e-05 23.4 0.0 6.2e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EAU93170.1 - 0.13 11.5 0.0 0.63 9.3 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 EAU93170.1 - 0.29 10.2 0.8 1.5 7.8 0.6 1.9 1 1 1 2 2 2 0 PAXNEB protein Ribosomal_L4 PF00573.22 EAU93171.1 - 2.3e-58 197.1 0.0 2.8e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.19 EAU93172.2 - 3.2e-32 111.6 0.2 3.6e-32 111.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT_2 PF16589.5 EAU93173.2 - 3.1e-19 69.2 0.0 1.8e-11 44.2 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EAU93173.2 - 0.029 14.8 0.0 0.2 12.1 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Tim17 PF02466.19 EAU93174.1 - 9.4e-09 35.6 8.8 1.4e-08 35.1 8.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SARAF PF06682.12 EAU93174.1 - 0.2 11.2 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis WD40 PF00400.32 EAU93175.2 - 1.4e-09 38.4 1.8 0.0015 19.3 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat TAFH PF07531.14 EAU93177.1 - 2.9e-09 36.9 0.1 1.7 8.8 0.0 4.4 1 1 3 4 4 4 4 NHR1 homology to TAF TNT PF14021.6 EAU93177.1 - 0.00046 20.7 1.0 26 5.5 0.0 4.3 4 0 0 4 4 4 2 Tuberculosis necrotizing toxin MdcG PF10620.9 EAU93177.1 - 0.13 12.0 3.7 2.8 7.7 0.3 2.4 1 1 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG NUC153 PF08159.12 EAU93178.1 - 1.2e-15 57.0 10.1 5.3e-15 54.9 1.2 3.5 3 0 0 3 3 3 2 NUC153 domain CS PF04969.16 EAU93179.1 - 4.2e-20 72.6 0.1 6.5e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 CS domain Ebola_NP PF05505.12 EAU93179.1 - 0.036 12.4 0.5 0.039 12.3 0.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PINIT PF14324.6 EAU93180.2 - 9.1e-42 142.8 1.1 1.5e-41 142.1 1.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EAU93180.2 - 4.5e-16 58.3 6.4 1e-15 57.2 6.4 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EAU93180.2 - 1.7e-07 30.9 2.3 4.8e-07 29.5 2.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EAU93180.2 - 0.0068 16.1 0.5 0.029 14.1 0.1 2.3 2 0 0 2 2 2 1 SAP domain Mito_carr PF00153.27 EAU93181.2 - 1.5e-66 220.4 6.6 9.3e-25 86.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ResIII PF04851.15 EAU93182.2 - 8.7e-19 68.2 0.0 1.8e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EAU93182.2 - 5.7e-17 62.1 0.1 3.5e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU93182.2 - 8.4e-16 58.2 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EAU93182.2 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SWI2_SNF2 PF18766.1 EAU93182.2 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_30 PF13604.6 EAU93182.2 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EAU93182.2 - 0.0043 17.3 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EAU93182.2 - 0.018 15.4 0.0 0.45 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EAU93182.2 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NUDIX PF00293.28 EAU93184.2 - 1.1e-05 25.4 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NPL4 PF05021.15 EAU93185.2 - 2.8e-101 338.9 0.0 3.6e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EAU93185.2 - 1.7e-65 219.6 0.1 3.1e-65 218.7 0.1 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EAU93185.2 - 3.9e-05 24.1 0.0 7.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.15 EAU93186.2 - 3.5e-10 39.8 10.0 1e-09 38.3 9.9 1.8 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EAU93186.2 - 0.0002 21.4 6.7 0.00056 19.9 6.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EAU93186.2 - 0.016 15.7 3.5 0.039 14.5 3.5 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor CCDC85 PF10226.9 EAU93186.2 - 0.031 13.9 0.6 0.058 13.1 0.6 1.4 1 0 0 1 1 1 0 CCDC85 family CHCH PF06747.13 EAU93187.1 - 1.4e-05 25.1 0.2 1.9e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 CHCH domain Sld5 PF05916.11 EAU93187.1 - 0.14 12.6 0.1 0.22 12.0 0.1 1.3 1 1 0 1 1 1 0 GINS complex protein GDPD PF03009.17 EAU93188.2 - 7.5e-27 94.7 0.0 5.3e-19 69.0 0.0 2.1 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EAU93188.2 - 1.7e-07 31.5 0.7 1.2e-05 25.6 0.2 2.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family ThiG PF05690.14 EAU93188.2 - 0.071 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG SPC22 PF04573.12 EAU93188.2 - 0.1 12.1 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Signal peptidase subunit UPF0121 PF03661.13 EAU93190.2 - 4.9e-45 153.8 1.3 5.6e-45 153.6 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) PTH2 PF01981.16 EAU93191.2 - 3.8e-43 146.5 0.1 5.1e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Pkinase PF00069.25 EAU93192.1 - 1.5e-41 142.5 0.0 9.9e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93192.1 - 5.9e-12 45.4 0.0 5.6e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU93192.1 - 0.097 11.4 0.1 0.097 11.4 0.1 1.9 2 1 0 2 2 2 0 Fungal protein kinase RRP36 PF06102.12 EAU93194.2 - 3.1e-35 121.6 11.0 3.1e-35 121.6 11.0 2.2 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Ribosomal_L27e PF01777.18 EAU93194.2 - 3.3 8.1 7.0 0.71 10.3 2.4 2.3 2 0 0 2 2 2 0 Ribosomal L27e protein family Exonuc_VII_L PF02601.15 EAU93194.2 - 3.6 7.1 9.0 0.48 9.9 3.0 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit CorA PF01544.18 EAU93195.2 - 7.5e-18 64.9 2.4 9.8e-08 31.7 0.0 3.4 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein TACC_C PF05010.14 EAU93196.1 - 0.006 16.4 0.7 0.01 15.7 0.7 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Baculo_PEP_C PF04513.12 EAU93196.1 - 0.038 14.0 0.2 0.063 13.3 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1489 PF07370.11 EAU93196.1 - 0.038 13.7 0.2 0.47 10.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1489) Spc7 PF08317.11 EAU93196.1 - 0.071 12.0 2.9 0.11 11.4 2.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ApoO PF09769.9 EAU93196.1 - 0.1 12.6 0.4 0.31 11.0 0.2 1.8 1 1 0 1 1 1 0 Apolipoprotein O UPF0449 PF15136.6 EAU93196.1 - 0.16 12.4 1.2 0.45 11.0 0.9 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 RRM_5 PF13893.6 EAU93196.1 - 0.26 10.9 0.2 0.47 10.1 0.2 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APG6_N PF17675.1 EAU93196.1 - 1 9.9 5.5 1.9 9.0 5.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Pex16 PF08610.10 EAU93197.2 - 3.5e-107 358.3 1.9 4e-107 358.1 1.9 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF866 PF05907.13 EAU93199.2 - 8.4e-56 188.2 0.7 9.5e-56 188.0 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 EAU93199.2 - 0.012 15.5 0.7 0.39 10.7 0.1 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HalOD2 PF18547.1 EAU93199.2 - 0.27 11.2 1.8 4.9 7.1 0.1 2.8 3 0 0 3 3 3 0 Halobacterial output domain 2 MRP-S28 PF10213.9 EAU93200.2 - 2.7e-28 98.9 0.0 4.5e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Septin PF00735.18 EAU93202.1 - 5.4e-121 403.2 0.0 5.4e-121 403.2 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EAU93202.1 - 1.2e-07 31.8 0.7 3.7e-07 30.2 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EAU93202.1 - 5.5e-05 22.8 4.2 0.007 15.9 0.0 3.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EAU93202.1 - 0.00063 20.0 0.2 0.0086 16.3 0.0 2.8 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAU93202.1 - 0.00064 19.7 11.0 0.00094 19.1 0.6 3.5 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EAU93202.1 - 0.0022 18.4 0.3 0.01 16.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EAU93202.1 - 0.0043 17.1 3.2 1.9 8.5 0.0 3.3 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.16 EAU93202.1 - 0.0051 16.2 0.4 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 EAU93202.1 - 0.0053 16.4 0.0 0.027 14.1 0.0 2.2 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.27 EAU93202.1 - 0.006 17.1 6.6 0.079 13.5 1.1 2.8 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EAU93202.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EAU93202.1 - 0.022 15.0 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EAU93202.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 EAU93202.1 - 0.097 12.2 3.7 0.18 11.3 3.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF87 PF01935.17 EAU93202.1 - 0.13 12.4 2.1 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain Atg14 PF10186.9 EAU93202.1 - 0.36 9.9 4.3 0.56 9.2 4.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP_bind_1 PF03029.17 EAU93202.1 - 0.63 9.8 8.1 1.5 8.5 0.1 3.4 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Dzip-like_N PF13815.6 EAU93202.1 - 1.9 8.5 7.8 4.4 7.3 7.8 1.6 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Strep_SA_rep PF06696.11 EAU93202.1 - 2.4 8.3 9.2 0.28 11.2 3.8 2.2 1 1 1 2 2 2 0 Streptococcal surface antigen repeat DUF4140 PF13600.6 EAU93202.1 - 2.5 8.6 4.9 86 3.7 5.3 3.0 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Xpo1 PF08389.12 EAU93203.1 - 2.3e-21 76.4 0.0 2.6e-20 73.0 0.0 2.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EAU93203.1 - 3.1e-08 33.4 0.1 2.1e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3730 PF12530.8 EAU93203.1 - 0.0054 16.3 0.0 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3730) HEAT PF02985.22 EAU93203.1 - 0.0059 16.8 0.1 2 8.9 0.0 3.7 2 0 0 2 2 2 1 HEAT repeat Cnd1 PF12717.7 EAU93203.1 - 0.012 15.6 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EAU93203.1 - 0.017 15.7 0.3 0.2 12.2 0.0 3.2 3 1 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 EAU93203.1 - 0.018 15.4 0.1 0.51 10.8 0.0 3.3 3 0 0 3 3 3 0 HEAT repeats DUF2236 PF09995.9 EAU93203.1 - 0.028 14.6 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Importin_rep PF18773.1 EAU93203.1 - 0.047 13.4 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat CoA_binding PF02629.19 EAU93204.2 - 9.3e-30 103.2 1.1 1.6e-29 102.4 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EAU93204.2 - 4.9e-24 84.9 0.2 7.4e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EAU93204.2 - 4.7e-10 39.4 0.1 1.7e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EAU93204.2 - 4.9e-05 23.8 0.1 0.00032 21.2 0.0 2.4 3 0 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.22 EAU93204.2 - 0.0075 17.1 0.1 0.031 15.1 0.0 2.0 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ACBP PF00887.19 EAU93205.1 - 2.4e-20 72.5 0.0 3.9e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 EAU93205.1 - 8.2e-14 51.5 0.0 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EAU93205.1 - 2.1e-13 50.6 0.0 3e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EAU93205.1 - 2.4e-12 46.7 0.1 3.7e-10 39.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EAU93205.1 - 1.4e-08 34.3 0.0 8.6e-07 28.8 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EAU93205.1 - 4.7e-08 33.4 0.0 2.1e-07 31.3 0.0 2.1 1 1 0 2 2 2 1 Ankyrin repeats (many copies) DUF1035 PF06281.12 EAU93205.1 - 0.075 13.0 0.6 0.12 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Ribosomal_S16 PF00886.19 EAU93206.1 - 1.3e-18 66.8 0.1 2.3e-18 66.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 LSM PF01423.22 EAU93207.1 - 4.8e-22 77.4 0.2 5.3e-22 77.3 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EAU93207.1 - 0.0016 18.5 0.0 0.002 18.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Arm PF00514.23 EAU93208.1 - 2.9e-94 306.6 11.6 2.6e-13 49.5 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EAU93208.1 - 5e-24 84.6 0.4 1e-23 83.6 0.4 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 EAU93208.1 - 1.4e-23 82.9 4.4 6.1e-09 36.2 0.1 6.2 4 1 3 7 7 6 4 HEAT-like repeat Arm_3 PF16186.5 EAU93208.1 - 7.6e-22 76.6 0.4 1.6e-21 75.6 0.4 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 EAU93208.1 - 9.7e-19 67.6 1.1 1.8e-06 28.3 0.0 5.5 2 1 2 6 6 6 4 HEAT repeats HEAT PF02985.22 EAU93208.1 - 1.8e-18 65.0 0.1 0.00016 21.6 0.0 6.3 6 0 0 6 6 6 4 HEAT repeat RICTOR_V PF14668.6 EAU93208.1 - 3.3e-06 27.2 1.0 0.0094 16.2 0.0 4.0 3 2 1 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 EAU93208.1 - 1.4e-05 23.9 0.0 0.00056 18.6 0.0 2.5 1 1 2 3 3 3 1 Adaptin N terminal region Arm_2 PF04826.13 EAU93208.1 - 0.00018 21.1 0.0 1.4 8.3 0.0 3.9 2 1 1 4 4 4 2 Armadillo-like HEAT_PBS PF03130.16 EAU93208.1 - 0.00021 21.7 1.2 0.69 10.8 0.1 4.5 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 EAU93208.1 - 0.00096 19.3 0.1 2.1 8.5 0.0 4.2 3 3 2 5 5 5 2 V-ATPase subunit H Mo25 PF08569.11 EAU93208.1 - 0.047 13.1 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Mo25-like V-ATPase_H_N PF03224.14 EAU93208.1 - 0.074 12.3 0.0 6.7 5.9 0.0 3.0 1 1 0 2 2 2 0 V-ATPase subunit H COX6A PF02046.15 EAU93210.1 - 2.2e-32 111.9 0.2 2.5e-32 111.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa NDUF_B4 PF07225.12 EAU93210.1 - 0.076 12.9 0.0 0.096 12.6 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Ribul_P_3_epim PF00834.19 EAU93213.2 - 2e-62 210.1 0.0 2.4e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 EAU93213.2 - 0.00011 21.6 0.2 0.00015 21.2 0.2 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PG_binding_3 PF09374.10 EAU93213.2 - 0.16 12.2 0.3 0.42 10.9 0.3 1.8 1 1 0 1 1 1 0 Predicted Peptidoglycan domain Gly_transf_sug PF04488.15 EAU93214.2 - 7.1e-05 23.4 0.0 0.00016 22.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EAU93214.2 - 0.02 14.3 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PK PF00224.21 EAU93215.1 - 3.8e-165 548.9 1.1 5.5e-165 548.4 1.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EAU93215.1 - 7e-37 126.2 0.1 2.5e-36 124.5 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EAU93215.1 - 6.6e-05 22.1 1.7 0.00011 21.4 0.8 1.9 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EAU93215.1 - 0.0024 16.9 0.0 0.02 13.9 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain MCM PF00493.23 EAU93216.1 - 1.1e-95 319.0 0.2 1.6e-95 318.5 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EAU93216.1 - 2.7e-35 121.0 0.1 4.7e-35 120.2 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EAU93216.1 - 1e-22 80.3 1.2 2e-22 79.4 1.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAU93216.1 - 1.5e-14 54.4 0.1 4.6e-14 52.9 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAU93216.1 - 7.9e-08 31.9 0.1 1.9e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EAU93216.1 - 0.0029 17.5 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EAU93216.1 - 0.019 14.7 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Rib_recp_KP_reg PF05104.12 EAU93216.1 - 3.4 8.7 8.7 0.66 11.0 3.7 2.1 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region WD40 PF00400.32 EAU93218.2 - 5.9e-32 109.2 13.5 1.9e-08 34.8 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU93218.2 - 1.3e-09 38.3 0.1 0.11 12.8 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EAU93218.2 - 0.00032 19.3 0.0 0.28 9.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.6 EAU93218.2 - 0.0043 16.7 0.0 0.28 10.7 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain Ge1_WD40 PF16529.5 EAU93218.2 - 0.011 14.7 2.8 1.1 8.1 0.1 2.8 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Myb_DNA-binding PF00249.31 EAU93219.2 - 5.9e-23 80.8 0.1 1.4e-12 47.6 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EAU93219.2 - 6.2e-19 68.0 0.0 2.8e-14 53.1 0.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain zf-C2H2 PF00096.26 EAU93219.2 - 3.8e-05 23.9 1.5 0.051 14.1 0.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EAU93219.2 - 5.8e-05 23.3 1.7 0.31 11.2 0.2 2.8 3 0 0 3 3 3 2 Aberrant zinc-finger SANT_DAMP1_like PF16282.5 EAU93219.2 - 0.006 16.8 0.0 0.19 12.0 0.0 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 zf-C2H2_4 PF13894.6 EAU93219.2 - 0.023 15.5 3.8 35 5.6 0.1 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 EAU93219.2 - 0.29 11.8 1.1 4.3 8.0 0.0 2.9 3 1 1 4 4 4 0 FOXP coiled-coil domain SGTA_dimer PF16546.5 EAU93220.2 - 9.5e-26 89.4 0.2 2e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EAU93220.2 - 1.9e-15 55.9 0.0 8.6e-09 34.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EAU93220.2 - 6.8e-12 44.5 0.0 3.5e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU93220.2 - 2.1e-10 40.1 0.0 0.00092 18.8 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 EAU93220.2 - 3.5e-10 39.3 0.0 2.2e-05 24.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EAU93220.2 - 4.9e-07 29.7 0.7 0.043 14.2 0.0 4.1 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EAU93220.2 - 8e-06 26.3 0.7 0.0038 17.9 0.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU93220.2 - 3.1e-05 23.7 0.1 0.00066 19.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EAU93220.2 - 8.4e-05 23.0 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EAU93220.2 - 0.00028 21.0 0.0 0.00059 19.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EAU93220.2 - 0.00086 19.9 0.3 0.0023 18.5 0.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EAU93220.2 - 0.0013 19.0 0.2 0.014 15.7 0.2 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 EAU93220.2 - 0.032 14.1 0.1 10 6.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EAU93220.2 - 0.081 12.1 0.0 3.4 6.8 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 EAU93220.2 - 0.15 12.5 0.0 0.7 10.3 0.0 1.9 2 1 0 2 2 2 0 Bacterial transcriptional activator domain STI1 PF17830.1 EAU93220.2 - 0.36 10.8 4.8 4 7.5 0.4 3.0 2 1 0 3 3 3 0 STI1 domain DUF3446 PF11928.8 EAU93220.2 - 1.6 9.1 11.1 0.06 13.7 3.9 2.4 2 1 1 3 3 3 0 Early growth response N-terminal domain Prp19 PF08606.11 EAU93221.1 - 1e-29 102.3 3.4 1.8e-29 101.5 3.4 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EAU93221.1 - 1e-11 45.1 0.6 0.013 16.3 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU93221.1 - 2.2e-10 40.7 0.0 7.1e-06 26.2 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 EAU93221.1 - 0.00016 21.8 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EAU93221.1 - 0.006 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 EAU93221.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Frtz PF11768.8 EAU93221.1 - 0.012 14.0 0.0 0.022 13.1 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz EspA PF03433.13 EAU93221.1 - 0.085 12.7 0.1 14 5.5 0.0 2.3 2 0 0 2 2 2 0 EspA-like secreted protein OPT PF03169.15 EAU93222.2 - 3.3e-176 587.5 58.9 3.8e-176 587.3 58.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TauD PF02668.16 EAU93223.2 - 1.3e-57 195.7 1.3 2e-57 195.0 1.3 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0128 PF03673.13 EAU93223.2 - 0.078 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) F-box-like PF12937.7 EAU93224.2 - 1.9e-06 27.7 2.7 4e-06 26.6 1.7 2.2 2 0 0 2 2 2 1 F-box-like Sec34 PF04136.15 EAU93224.2 - 0.13 12.1 0.1 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Sec34-like family Spc7 PF08317.11 EAU93226.1 - 4.9e-94 314.7 13.8 4.9e-94 314.7 13.8 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EAU93226.1 - 1.4e-07 31.5 0.0 2.9e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Spc7_C2 DUF3584 PF12128.8 EAU93226.1 - 0.024 12.2 14.5 0.04 11.4 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.11 EAU93226.1 - 0.024 13.5 12.3 0.065 12.1 12.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tektin PF03148.14 EAU93226.1 - 0.05 12.4 12.7 0.097 11.4 12.7 1.4 1 0 0 1 1 1 0 Tektin family Phage_GPO PF05929.11 EAU93226.1 - 0.38 10.3 8.3 0.89 9.1 8.3 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase HIP1_clath_bdg PF16515.5 EAU93226.1 - 0.5 11.0 18.4 0.29 11.7 10.5 3.6 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Borrelia_lipo_1 PF05714.11 EAU93226.1 - 0.61 9.8 8.8 1.1 9.0 8.8 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein TolA_bind_tri PF16331.5 EAU93226.1 - 1 9.5 13.9 0.013 15.5 4.6 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation Prominin PF05478.11 EAU93226.1 - 1.1 7.1 6.7 1.7 6.5 2.7 2.0 2 0 0 2 2 2 0 Prominin DUF5082 PF16888.5 EAU93226.1 - 2.5 8.4 13.7 1.4 9.2 3.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) GAS PF13851.6 EAU93226.1 - 4.7 6.5 17.5 29 3.9 17.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 EAU93226.1 - 6.7 6.2 11.3 7.5 6.0 6.9 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 EAU93226.1 - 9.2 6.4 8.2 8.4 6.6 5.7 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Kinesin PF00225.23 EAU93227.2 - 5.2e-82 275.5 0.0 1e-81 274.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EAU93227.2 - 4.7e-15 55.8 0.0 3.9e-12 46.4 0.0 2.8 2 0 0 2 2 2 2 Microtubule binding Nop14 PF04147.12 EAU93227.2 - 0.013 13.7 34.9 0.023 13.0 34.9 1.3 1 0 0 1 1 1 0 Nop14-like family UDG PF03167.19 EAU93228.2 - 5.5e-15 55.7 0.1 1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Med3 PF11593.8 EAU93228.2 - 6 6.0 8.8 7.7 5.6 8.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MTS PF05175.14 EAU93229.2 - 1.6e-08 34.3 0.0 2.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EAU93229.2 - 5.9e-05 23.7 0.0 0.00018 22.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU93229.2 - 0.0012 19.5 0.0 0.0024 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU93229.2 - 0.0023 18.5 0.0 0.0042 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EAU93229.2 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.6 EAU93229.2 - 0.1 13.6 0.0 0.23 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EAU93229.2 - 0.18 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit C2 PF00168.30 EAU93230.2 - 7.5e-87 286.4 1.9 1.1e-18 67.4 0.1 5.4 5 0 0 5 5 5 5 C2 domain MLVIN_C PF18697.1 EAU93230.2 - 0.095 12.8 0.2 8.4 6.6 0.0 3.5 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Mito_carr PF00153.27 EAU93231.2 - 3.9e-16 58.7 0.0 0.0033 17.3 0.0 4.9 4 1 0 4 4 4 4 Mitochondrial carrier protein Cas_NE0113 PF09623.10 EAU93231.2 - 0.088 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Mei4 PF13971.6 EAU93233.2 - 0.06 12.8 0.0 0.14 11.6 0.0 1.5 2 0 0 2 2 2 0 Meiosis-specific protein Mei4 PHD PF00628.29 EAU93234.2 - 9.2e-11 41.5 8.4 1.6e-10 40.7 8.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EAU93234.2 - 0.00075 19.0 4.1 0.0014 18.2 4.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EAU93234.2 - 0.0081 16.2 2.1 0.02 14.9 2.1 1.7 1 0 0 1 1 1 1 CW-type Zinc Finger zf-PHD-like PF15446.6 EAU93234.2 - 0.011 15.3 1.2 0.029 14.0 1.2 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 EAU93234.2 - 0.3 11.0 6.5 0.19 11.7 3.9 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 UvrD_C PF13361.6 EAU93235.2 - 2e-10 40.6 0.0 1.4e-07 31.3 0.0 3.2 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EAU93235.2 - 1.7e-06 27.8 0.1 1.7e-06 27.8 0.1 3.5 5 0 0 5 5 5 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EAU93235.2 - 3.9e-06 26.6 0.0 0.0034 17.2 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EAU93235.2 - 3e-05 24.4 0.1 0.00034 21.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EAU93235.2 - 0.011 15.4 0.0 0.062 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.6 EAU93235.2 - 0.023 14.7 2.3 0.72 10.0 0.7 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 EAU93235.2 - 0.026 14.4 0.2 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS AAA_22 PF13401.6 EAU93235.2 - 0.039 14.2 0.1 0.37 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EAU93235.2 - 0.074 13.1 0.2 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EAU93235.2 - 0.12 12.1 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TMPIT PF07851.13 EAU93235.2 - 0.19 10.9 0.4 0.37 10.0 0.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein TPR_1 PF00515.28 EAU93235.2 - 0.48 10.3 7.4 2.8 7.9 0.9 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EAU93235.2 - 5.9 8.0 6.5 5.4 8.1 0.1 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat Spindle_Spc25 PF08234.12 EAU93236.2 - 7.1e-22 77.4 0.0 1.6e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Nup54 PF13874.6 EAU93236.2 - 0.0043 17.2 7.9 0.0067 16.5 7.9 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 RIB43A PF05914.12 EAU93236.2 - 0.036 12.8 8.9 0.053 12.3 8.9 1.2 1 0 0 1 1 1 0 RIB43A RasGAP_C PF03836.15 EAU93236.2 - 0.096 12.8 6.6 0.11 12.6 4.7 2.0 1 1 1 2 2 2 0 RasGAP C-terminus DUF4200 PF13863.6 EAU93236.2 - 0.13 12.7 10.2 0.25 11.8 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RTBV_P46 PF06216.11 EAU93236.2 - 0.23 10.3 1.8 0.3 9.9 1.8 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein CENP-H PF05837.12 EAU93236.2 - 1.8 9.0 13.2 1.7 9.1 11.9 1.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 EAU93236.2 - 3.6 8.3 8.4 25 5.6 3.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA CAF1-p150_C2 PF15539.6 EAU93239.2 - 0.14 11.6 2.0 14 5.1 0.7 3.0 2 1 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Ost5 PF05251.12 EAU93240.1 - 1.1e-21 76.9 9.7 1.2e-21 76.7 9.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF4728 PF15860.5 EAU93240.1 - 0.06 14.0 0.8 0.076 13.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4728) QCR10 PF09796.9 EAU93240.1 - 1.1 9.4 5.7 10 6.3 0.9 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TB2_DP1_HVA22 PF03134.19 EAU93241.1 - 9.1e-26 89.6 7.4 1.7e-25 88.7 7.4 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MFS_1 PF07690.16 EAU93242.2 - 5.5e-21 74.9 32.5 8.1e-21 74.3 32.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EAU93242.2 - 1.7e-13 50.6 8.1 1.7e-13 50.6 8.1 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 HAD_2 PF13419.6 EAU93243.1 - 9.5e-05 22.6 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ArfGap PF01412.18 EAU93244.1 - 2.1e-42 143.9 0.2 3.1e-42 143.4 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PDZ_5 PF17817.1 EAU93245.2 - 0.082 13.2 0.0 0.32 11.3 0.0 2.0 1 0 0 1 1 1 0 PDZ domain DAO PF01266.24 EAU93246.1 - 1.1e-36 127.1 0.1 1.5e-36 126.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EAU93246.1 - 0.0099 16.1 0.2 0.059 13.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EAU93246.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EAU93246.1 - 0.099 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding RNA_pol_Rpb1_1 PF04997.12 EAU93247.2 - 2.3e-110 368.8 0.0 3.3e-110 368.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EAU93247.2 - 1.5e-101 339.3 0.0 2.2e-101 338.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EAU93247.2 - 5e-74 248.0 0.0 1.1e-73 246.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EAU93247.2 - 2e-68 230.0 0.3 2e-68 230.0 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EAU93247.2 - 3.1e-51 173.4 0.0 9.9e-51 171.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EAU93247.2 - 1.2e-47 161.3 0.5 3.1e-47 159.9 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EAU93247.2 - 2.4e-37 127.2 0.1 4.9e-37 126.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EAU93247.2 - 0.00047 20.4 179.4 0.054 13.9 7.1 13.0 10 1 1 12 12 12 7 RNA polymerase Rpb1 C-terminal repeat DUF4360 PF14273.6 EAU93248.2 - 9.4e-46 155.9 0.4 2.2e-24 86.3 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4360) AMP-binding PF00501.28 EAU93249.2 - 9.3e-82 274.9 0.0 1.5e-81 274.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EAU93249.2 - 0.006 17.5 1.2 0.013 16.4 1.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAF-1_p150 PF11600.8 EAU93250.2 - 0.036 13.8 3.4 0.097 12.4 3.4 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Leu_zip PF15294.6 EAU93250.2 - 4 6.9 6.9 0.65 9.5 1.7 1.9 2 0 0 2 2 2 0 Leucine zipper D-ser_dehydrat PF14031.6 EAU93252.2 - 7.8e-21 74.6 0.1 4e-20 72.3 0.0 2.2 2 1 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EAU93252.2 - 6.3e-16 58.7 0.0 9.3e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ras PF00071.22 EAU93253.2 - 7.5e-32 110.2 0.1 1.1e-18 67.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EAU93253.2 - 1.3e-17 64.1 0.1 1.6e-16 60.6 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EAU93253.2 - 0.011 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EAU93253.2 - 0.023 15.1 0.1 0.043 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 EAU93253.2 - 0.054 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EAU93253.2 - 0.15 12.3 0.0 0.23 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Nop14 PF04147.12 EAU93265.2 - 0.012 13.9 18.1 0.017 13.4 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EAU93265.2 - 0.44 8.8 17.3 0.58 8.4 17.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EAU93265.2 - 0.48 9.3 3.8 0.69 8.8 3.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Med21 PF11221.8 EAU93265.2 - 0.69 10.2 0.0 0.69 10.2 0.0 3.7 2 1 0 2 2 1 0 Subunit 21 of Mediator complex SDA1 PF05285.12 EAU93265.2 - 1.1 8.6 24.7 0.062 12.7 19.0 1.8 2 0 0 2 2 2 0 SDA1 NOA36 PF06524.12 EAU93265.2 - 1.6 8.0 18.0 2.9 7.1 18.0 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EAU93265.2 - 2.6 6.5 12.6 3.7 6.0 12.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EAU93265.2 - 3.3 5.7 24.1 5.3 5.0 24.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2151 PF10221.9 EAU93265.2 - 4.4 5.8 9.5 6 5.3 9.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator Hid1 PF12722.7 EAU93265.2 - 6.1 4.8 7.7 6.6 4.7 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 EAU93265.2 - 6.1 5.5 12.2 9.4 4.9 12.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PI3K_1B_p101 PF10486.9 EAU93265.2 - 7.3 4.2 7.3 9.2 3.9 7.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Roughex PF06020.11 EAU93265.2 - 9.1 5.3 17.7 13 4.7 17.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 EAU93265.2 - 9.7 4.8 8.2 13 4.4 8.2 1.2 1 0 0 1 1 1 0 Presenilin HMG_box_2 PF09011.10 EAU93267.2 - 1.9 9.2 5.8 1.6 9.4 0.3 3.0 2 0 0 2 2 2 0 HMG-box domain KDZ PF18758.1 EAU93268.2 - 1.3e-44 152.5 0.4 2e-44 151.9 0.4 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU93268.2 - 4e-22 78.4 0.1 8.9e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU93268.2 - 0.047 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Glycos_transf_2 PF00535.26 EAU93273.2 - 9.8e-34 116.6 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EAU93273.2 - 1.5e-13 51.1 0.0 2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EAU93273.2 - 1.4e-05 24.7 0.0 1.8e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EAU93273.2 - 0.034 14.7 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 F-box PF00646.33 EAU93274.2 - 1.8e-08 34.0 0.2 3e-08 33.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU93274.2 - 7.1e-08 32.2 0.2 1.5e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 EAU93274.2 - 4.3 7.9 10.0 0.47 11.0 4.0 2.2 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Sel1 PF08238.12 EAU93275.2 - 1.1e-18 67.2 7.1 5.7e-06 26.8 0.0 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.6 EAU93275.2 - 0.013 16.1 0.1 0.04 14.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU93275.2 - 0.086 13.0 1.7 14 6.0 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HA2 PF04408.23 EAU93276.2 - 4e-23 81.7 0.0 4e-23 81.7 0.0 3.8 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EAU93276.2 - 8.8e-16 58.0 0.0 2.6e-15 56.5 0.0 1.8 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EAU93276.2 - 7.2e-13 48.9 0.0 1.7e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EAU93276.2 - 3.9e-09 36.5 0.0 8.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EAU93276.2 - 1.2e-05 25.5 0.2 4.4e-05 23.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EAU93276.2 - 0.00016 21.5 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EAU93276.2 - 0.00053 19.3 0.0 0.00099 18.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EAU93276.2 - 0.0015 18.9 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EAU93276.2 - 0.0067 15.5 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 EAU93276.2 - 0.011 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 EAU93276.2 - 0.02 14.9 0.0 9 6.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EAU93276.2 - 0.032 14.3 0.1 0.25 11.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAU93276.2 - 0.047 13.1 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 EAU93276.2 - 0.053 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EAU93276.2 - 0.054 14.0 0.0 0.23 12.0 0.0 2.1 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 EAU93276.2 - 0.057 13.1 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EAU93276.2 - 0.085 13.0 0.0 0.38 10.9 0.0 2.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EAU93276.2 - 0.092 12.4 0.2 0.26 10.9 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EAU93276.2 - 0.14 12.5 0.2 0.53 10.7 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain NACHT PF05729.12 EAU93276.2 - 0.15 12.0 0.1 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain L51_S25_CI-B8 PF05047.16 EAU93277.1 - 2.2e-06 27.5 0.1 3.6e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain GET2 PF08690.10 EAU93278.2 - 2.2e-12 47.3 0.0 4.2e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 GET complex subunit GET2 CAML PF14963.6 EAU93278.2 - 0.0026 17.9 2.6 0.48 10.5 0.4 2.1 2 0 0 2 2 2 2 Calcium signal-modulating cyclophilin ligand Vps35 PF03635.17 EAU93279.2 - 1.6e-297 989.0 0.0 1.9e-297 988.8 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF913 PF06025.12 EAU93279.2 - 3 6.7 5.5 12 4.7 0.8 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MFS_1 PF07690.16 EAU93280.1 - 1e-19 70.7 31.1 1e-19 70.7 31.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0220 PF05255.11 EAU93280.1 - 0.031 13.8 0.2 0.087 12.4 0.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) BCIP PF13862.6 EAU93281.1 - 1.7e-65 220.7 0.0 2.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF4250 PF14056.6 EAU93281.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DUF4360 PF14273.6 EAU93282.2 - 5.6e-34 117.5 0.0 7.2e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pox_Ag35 PF03286.14 EAU93283.1 - 6.1 6.6 12.0 1.4 8.7 2.3 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nic96 PF04097.14 EAU93284.1 - 2.7e-159 531.6 0.0 3.3e-159 531.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Actin PF00022.19 EAU93285.1 - 2.1e-44 151.7 0.0 9.8e-22 77.1 0.0 2.2 2 0 0 2 2 2 2 Actin Atrophin-1 PF03154.15 EAU93285.1 - 2.3 6.4 17.1 4.1 5.6 17.1 1.3 1 0 0 1 1 1 0 Atrophin-1 family DUF3040 PF11239.8 EAU93285.1 - 2.3 8.5 4.0 0.55 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) IFP_35_N PF07334.13 EAU93285.1 - 2.5 8.2 6.4 0.19 11.8 0.7 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ras PF00071.22 EAU93286.1 - 1.7e-64 216.3 0.0 2e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU93286.1 - 6e-34 116.8 0.1 1.1e-33 116.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EAU93286.1 - 1.7e-14 53.6 0.1 2.3e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EAU93286.1 - 7.2e-06 25.7 0.1 1.7e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EAU93286.1 - 9e-05 21.9 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EAU93286.1 - 9.1e-05 22.4 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EAU93286.1 - 9.4e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EAU93286.1 - 0.01 15.4 0.0 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 EAU93286.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EAU93286.1 - 0.039 13.4 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EAU93286.1 - 0.043 13.6 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 EAU93286.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 EAU93286.1 - 0.083 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA PF00004.29 EAU93286.1 - 0.094 13.1 0.0 0.79 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EAU93286.1 - 0.13 11.3 0.0 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain DUF4360 PF14273.6 EAU93296.2 - 8.6e-49 165.8 0.6 1e-48 165.5 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.16 EAU93297.2 - 8.3e-13 48.0 45.5 1.3e-07 30.9 30.8 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily YL1 PF05764.13 EAU93298.2 - 1.3e-26 94.2 30.9 1.3e-26 94.2 30.9 1.6 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EAU93298.2 - 2.8e-13 49.4 0.0 4.3e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF4360 PF14273.6 EAU93299.2 - 4.6e-62 209.0 0.5 5.3e-62 208.8 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DNA_methylase PF00145.17 EAU93300.2 - 4.5e-20 72.3 0.0 5.6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Thiolase_N PF00108.23 EAU93301.1 - 1.5e-13 50.7 0.2 2.7e-11 43.3 0.2 2.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EAU93301.1 - 3.1e-07 30.1 0.1 3.2e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EAU93301.1 - 3.3e-05 23.6 0.7 0.45 10.1 0.0 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EAU93301.1 - 0.00094 19.0 0.0 0.35 10.8 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III VHS PF00790.19 EAU93302.2 - 1.2e-43 148.3 3.9 2.1e-43 147.6 0.0 2.6 3 0 0 3 3 3 1 VHS domain FYVE PF01363.21 EAU93302.2 - 8.5e-17 61.1 5.9 1.5e-16 60.2 5.9 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EAU93302.2 - 4e-06 26.4 13.2 0.00072 19.3 4.1 3.0 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 EAU93302.2 - 0.018 15.3 0.8 0.044 14.1 0.2 1.9 2 0 0 2 2 2 0 GAT domain FYVE_2 PF02318.16 EAU93302.2 - 0.15 12.3 6.0 0.038 14.2 2.5 1.7 2 0 0 2 2 2 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 EAU93302.2 - 0.21 11.5 1.4 0.66 9.9 1.4 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.7 EAU93302.2 - 0.65 10.1 6.5 8.9 6.4 3.8 2.4 1 1 1 2 2 2 0 Double zinc ribbon Pro_dh PF01619.18 EAU93303.2 - 5.5e-49 167.3 0.0 3.9e-48 164.5 0.0 2.3 1 1 0 1 1 1 1 Proline dehydrogenase DUF4360 PF14273.6 EAU93304.1 - 9.8e-62 208.0 0.4 1.1e-61 207.8 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF460 PF04312.13 EAU93304.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) ResIII PF04851.15 EAU93305.2 - 3.9e-08 33.5 0.0 1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EAU93305.2 - 3.6e-06 26.8 0.0 9.5e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase G-patch PF01585.23 EAU93306.2 - 1.9e-10 40.4 0.1 5e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 EAU93306.2 - 6.3e-07 29.5 6.6 1e-06 28.9 6.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 EAU93306.2 - 1.6e-06 28.1 1.3 3.9e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 G-patch domain zf-met PF12874.7 EAU93306.2 - 2.6e-05 24.4 2.5 4.4e-05 23.7 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EAU93306.2 - 0.0092 16.3 0.4 0.016 15.5 0.4 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 EAU93306.2 - 0.022 14.9 0.3 0.036 14.2 0.3 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 EAU93306.2 - 0.043 14.3 1.2 0.082 13.4 1.2 1.4 1 0 0 1 1 1 0 Zinc-finger double domain DUF4820 PF16091.5 EAU93306.2 - 0.12 11.8 9.4 0.2 11.0 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) zf-DBF PF07535.12 EAU93306.2 - 0.19 11.9 2.4 0.31 11.2 2.4 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.26 EAU93306.2 - 0.38 11.3 2.4 0.7 10.5 2.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Frataxin_Cyay PF01491.16 EAU93309.1 - 7.1e-40 135.4 0.0 8e-40 135.3 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain NACHT PF05729.12 EAU93311.2 - 3.5e-10 40.0 0.0 1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU93311.2 - 5.6e-05 23.6 0.0 0.00013 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAU93311.2 - 0.0011 19.5 0.0 0.0028 18.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EAU93311.2 - 0.024 14.6 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAU93311.2 - 0.03 14.6 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EAU93311.2 - 0.04 13.0 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_PrkA PF08298.11 EAU93311.2 - 0.078 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RuvB_N PF05496.12 EAU93311.2 - 0.1 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EAU93311.2 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EAU93311.2 - 0.21 12.0 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Trypsin_2 PF13365.6 EAU93312.2 - 1.3e-10 42.4 1.6 4.9e-10 40.5 0.1 2.2 1 1 1 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EAU93312.2 - 0.28 11.0 1.0 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Trypsin CbtA PF09490.10 EAU93313.1 - 0.0078 16.0 2.1 0.012 15.4 2.1 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) GP67 PF17634.2 EAU93313.1 - 0.02 15.3 5.0 0.034 14.5 5.0 1.3 1 0 0 1 1 1 0 Gene product 67 ApeC PF16977.5 EAU93313.1 - 0.13 12.1 0.2 2.3 8.1 0.0 2.4 2 1 0 2 2 2 0 C-terminal domain of apextrin PGM_PMM_I PF02878.16 EAU93313.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF2796 PF10986.8 EAU93313.1 - 0.44 10.5 17.5 0.66 9.9 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Zip PF02535.22 EAU93313.1 - 0.6 9.3 3.6 0.91 8.7 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 EAU93313.1 - 0.63 9.4 12.3 0.93 8.8 12.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NOA36 PF06524.12 EAU93313.1 - 2 7.6 8.3 2.7 7.2 8.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EAU93313.1 - 2.6 7.1 7.5 3.8 6.5 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rhodanese PF00581.20 EAU93314.1 - 3.7e-15 56.4 0.0 1.2e-14 54.7 0.0 1.7 1 1 1 2 2 2 1 Rhodanese-like domain DUF3501 PF12007.8 EAU93314.1 - 0.21 11.5 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) NACHT PF05729.12 EAU93315.2 - 1.7e-12 47.6 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU93315.2 - 7.9e-07 29.6 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EAU93315.2 - 3.3e-05 24.3 0.0 9.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EAU93315.2 - 0.00075 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EAU93315.2 - 0.0043 17.3 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EAU93315.2 - 0.0083 16.1 0.0 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 EAU93315.2 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NTPase_1 PF03266.15 EAU93315.2 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 EAU93315.2 - 0.02 14.4 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EAU93315.2 - 0.031 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EAU93315.2 - 0.032 14.6 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.11 EAU93315.2 - 0.035 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RuvB_N PF05496.12 EAU93315.2 - 0.05 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EAU93315.2 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EAU93315.2 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EAU93315.2 - 0.19 10.9 0.3 3.2 6.9 0.1 2.1 1 1 1 2 2 2 0 KAP family P-loop domain SRP54 PF00448.22 EAU93315.2 - 0.21 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Urb2 PF10441.9 EAU93316.2 - 2.5e-48 164.7 0.5 2.5e-48 164.7 0.5 3.6 4 1 0 5 5 5 1 Urb2/Npa2 family FANCI_S2 PF14676.6 EAU93316.2 - 0.046 14.0 1.4 11 6.3 0.0 2.9 2 0 0 2 2 2 0 FANCI solenoid 2 KH_1 PF00013.29 EAU93319.1 - 8.9e-43 144.0 2.3 3e-10 39.8 0.0 7.4 7 0 0 7 7 7 7 KH domain Ku PF02735.16 EAU93320.2 - 2.2e-30 105.9 0.0 8e-30 104.1 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EAU93320.2 - 7.1e-28 97.2 0.1 2.2e-27 95.6 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 EAU93320.2 - 1.4e-07 31.5 0.0 1e-05 25.4 0.0 2.5 1 1 1 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EAU93320.2 - 8.6e-05 23.2 0.1 8.6e-05 23.2 0.1 2.9 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 EAU93320.2 - 0.00018 21.8 0.0 0.00042 20.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EAU93320.2 - 0.0022 18.6 0.0 0.0066 17.1 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain SNF2_N PF00176.23 EAU93321.2 - 1.3e-72 244.4 1.0 4.2e-72 242.8 1.0 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EAU93321.2 - 1.6e-22 79.4 0.3 6.1e-22 77.5 0.1 2.1 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.31 EAU93321.2 - 4.1e-21 75.4 1.4 6.3e-18 65.1 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 EAU93321.2 - 5.7e-17 61.8 8.6 5.7e-17 61.8 8.6 4.4 5 0 0 5 5 5 1 HSA QLQ PF08880.11 EAU93321.2 - 1.3e-15 56.8 0.8 4.9e-15 55.0 0.8 2.1 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 EAU93321.2 - 1.2e-10 41.8 0.2 1.2e-10 41.8 0.2 3.9 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EAU93321.2 - 1.1e-08 35.3 0.4 5.3e-08 33.0 0.1 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit bZIP_1 PF00170.21 EAU93322.2 - 4.2e-11 42.8 14.9 7.9e-11 41.9 14.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EAU93322.2 - 3.8e-05 23.6 0.1 3.8e-05 23.6 0.1 3.5 2 1 1 3 3 1 1 Transcription factor PAP1 bZIP_2 PF07716.15 EAU93322.2 - 0.00018 21.5 16.4 0.00018 21.5 16.4 2.2 1 1 1 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 EAU93322.2 - 0.0051 16.6 9.5 0.0051 16.6 9.5 1.9 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 T4SS PF07996.11 EAU93322.2 - 0.0058 17.1 7.7 0.013 16.0 7.7 1.5 1 0 0 1 1 1 1 Type IV secretion system proteins DivIC PF04977.15 EAU93322.2 - 0.08 12.7 3.7 0.18 11.6 3.7 1.6 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.18 EAU93322.2 - 0.17 12.2 5.6 1.3 9.4 5.6 2.3 1 1 0 1 1 1 0 TSC-22/dip/bun family ATG16 PF08614.11 EAU93322.2 - 0.17 12.1 21.0 0.16 12.2 15.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) YabA PF06156.13 EAU93322.2 - 0.2 12.3 3.3 0.46 11.2 3.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA XhlA PF10779.9 EAU93322.2 - 1.4 9.1 4.6 3.6 7.9 4.6 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF3450 PF11932.8 EAU93322.2 - 1.5 8.1 8.1 2.4 7.4 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) rRNA_processing PF08524.11 EAU93322.2 - 9.4 6.3 17.5 20 5.2 17.5 1.5 1 0 0 1 1 1 0 rRNA processing TPR_1 PF00515.28 EAU93324.2 - 2.6e-49 163.1 25.4 8.8e-08 31.7 0.0 9.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EAU93324.2 - 5e-46 151.1 17.7 1.4e-05 24.9 0.2 9.7 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 EAU93324.2 - 1.6e-37 124.5 10.7 0.00048 20.1 1.6 9.7 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 EAU93324.2 - 1.2e-27 96.2 9.1 8.1e-05 23.2 0.3 6.3 1 1 7 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 EAU93324.2 - 1.2e-26 91.1 7.6 0.0065 17.2 0.0 9.1 2 2 7 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 EAU93324.2 - 4.1e-25 87.9 12.4 2.9e-05 24.2 1.1 6.9 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 EAU93324.2 - 8e-24 82.3 13.6 0.00081 19.6 0.3 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EAU93324.2 - 9.5e-24 83.7 10.6 0.00034 21.1 0.5 6.4 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.6 EAU93324.2 - 5.8e-23 80.3 30.0 3.5e-06 26.6 0.4 8.6 5 3 4 9 9 9 7 TPR repeat TPR_7 PF13176.6 EAU93324.2 - 1.7e-21 74.6 11.3 0.016 15.2 0.0 8.6 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 EAU93324.2 - 7.5e-20 70.2 13.5 0.063 13.9 0.0 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 EAU93324.2 - 5.2e-13 49.0 9.6 0.019 15.1 0.1 6.1 1 1 7 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EAU93324.2 - 2.7e-12 46.7 6.5 4.7e-06 26.7 1.3 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EAU93324.2 - 5e-06 25.9 4.0 1.4 8.1 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 EAU93324.2 - 2.2e-05 24.3 1.3 0.57 9.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EAU93324.2 - 0.00036 20.8 0.1 0.017 15.4 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EAU93324.2 - 0.00038 19.9 0.2 0.026 13.9 0.0 2.6 2 1 1 3 3 3 1 MalT-like TPR region SNAP PF14938.6 EAU93324.2 - 0.001 18.6 7.8 4.3 6.7 0.0 4.4 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP DUF2225 PF09986.9 EAU93324.2 - 0.0014 18.4 0.5 0.59 9.8 0.0 2.8 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 EAU93324.2 - 0.039 13.7 0.6 4.8 6.9 0.0 3.5 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 EAU93324.2 - 0.18 11.8 15.0 0.21 11.5 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EAU93324.2 - 0.3 11.2 1.8 44 4.3 0.0 4.0 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 EAU93324.2 - 0.34 11.6 3.3 25 5.7 0.0 3.5 3 0 0 3 3 2 0 Sel1 repeat BTAD PF03704.17 EAU93324.2 - 0.46 10.9 2.8 5.4 7.4 0.3 3.0 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_3 PF07720.12 EAU93324.2 - 1.2 9.3 28.6 1.6 8.8 0.7 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Brr6_like_C_C PF10104.9 EAU93327.2 - 3.4e-44 149.9 1.2 4.3e-44 149.5 1.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ctr PF04145.15 EAU93327.2 - 0.14 12.8 0.0 0.77 10.4 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Ost5 PF05251.12 EAU93327.2 - 2.3 8.5 6.0 1.8 8.9 1.6 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 DUF3328 PF11807.8 EAU93327.2 - 3 7.6 5.3 0.82 9.4 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) CLP_protease PF00574.23 EAU93328.2 - 1.8e-73 246.3 0.0 2.2e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease ECH_1 PF00378.20 EAU93328.2 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Reprolysin_5 PF13688.6 EAU93329.2 - 6.1e-44 150.5 0.3 6.1e-44 150.5 0.3 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EAU93329.2 - 1.4e-40 139.3 0.1 1.4e-40 139.3 0.1 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EAU93329.2 - 3.7e-37 127.9 0.0 6.8e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EAU93329.2 - 1.4e-17 64.2 22.5 1.4e-17 64.2 22.5 4.5 3 1 1 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 EAU93329.2 - 3.2e-11 43.8 0.0 9.5e-11 42.3 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EAU93329.2 - 1.2e-06 28.5 3.0 5.3e-06 26.5 3.0 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 EAU93329.2 - 2e-05 25.0 7.9 2e-05 25.0 7.9 3.2 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 EAU93329.2 - 2e-05 24.8 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Myc_target_1 PF15179.6 EAU93329.2 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Myc target protein 1 DEAD PF00270.29 EAU93330.1 - 3.7e-47 160.3 0.8 1.2e-46 158.7 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EAU93330.1 - 1.5e-32 112.3 0.1 2.4e-28 98.7 0.0 3.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EAU93330.1 - 0.00074 18.4 0.0 0.0021 16.9 0.0 1.8 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 EAU93330.1 - 0.0068 15.8 0.1 0.0068 15.8 0.1 4.5 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EAU93330.1 - 0.07 13.4 0.3 1.2 9.4 0.0 2.8 3 1 0 3 3 3 0 AAA domain LytR_C PF13399.6 EAU93330.1 - 0.11 13.5 0.4 78 4.4 0.0 4.2 4 0 0 4 4 4 0 LytR cell envelope-related transcriptional attenuator Nop14 PF04147.12 EAU93330.1 - 0.15 10.3 45.3 0.24 9.6 45.3 1.2 1 0 0 1 1 1 0 Nop14-like family GREB1 PF15782.5 EAU93330.1 - 9.8 3.1 27.7 14 2.7 27.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Oxysterol_BP PF01237.18 EAU93331.2 - 2.5e-83 280.0 0.0 4.9e-81 272.4 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein NACHT PF05729.12 EAU93332.2 - 6.3e-10 39.2 0.0 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EAU93332.2 - 0.00035 21.0 0.0 0.00094 19.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EAU93332.2 - 0.00077 19.9 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EAU93332.2 - 0.014 15.7 0.0 0.05 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EAU93332.2 - 0.042 13.9 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EAU93332.2 - 0.17 11.6 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF4832 PF16116.5 EAU93333.1 - 0.041 13.7 0.1 0.89 9.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4832) PAM2 PF07145.15 EAU93335.2 - 0.0064 16.1 1.5 3.1 7.7 0.1 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Tropomyosin PF00261.20 EAU93335.2 - 7.7 5.8 63.4 13 5.1 25.0 4.4 2 1 1 3 3 3 0 Tropomyosin Aminotran_4 PF01063.19 EAU93336.2 - 1.9e-31 109.6 0.0 4.1e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV PWI PF01480.17 EAU93337.2 - 2.4e-10 40.6 0.3 4.9e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 PWI domain zf-CCCH PF00642.24 EAU93337.2 - 1.1e-05 25.2 6.5 2e-05 24.4 6.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 EAU93337.2 - 7.9e-05 22.7 3.4 0.014 15.5 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif RRM_1 PF00076.22 EAU93337.2 - 0.00018 21.2 0.0 0.00092 19.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EAU93337.2 - 0.0011 19.0 7.9 0.002 18.1 7.9 1.5 1 0 0 1 1 1 1 Zinc finger domain DUF4407 PF14362.6 EAU93337.2 - 0.034 13.5 7.2 0.053 12.9 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCCD1 PF15707.5 EAU93337.2 - 0.056 13.9 4.7 0.21 12.1 4.7 1.9 1 0 0 1 1 1 0 Mitochondrial coiled-coil domain protein 1 PRKG1_interact PF15898.5 EAU93337.2 - 0.2 12.6 4.4 0.37 11.7 4.4 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF3584 PF12128.8 EAU93337.2 - 0.24 8.8 4.7 0.34 8.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-CCCH_2 PF14608.6 EAU93337.2 - 1.1 9.8 3.5 2.1 9.0 3.5 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Rhodanese PF00581.20 EAU93339.2 - 3.8e-18 66.0 0.0 5.4e-10 39.7 0.0 2.5 2 1 0 2 2 2 2 Rhodanese-like domain ACP_syn_III_C PF08541.10 EAU93339.2 - 0.032 14.4 0.0 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal V-ATPase_C PF03223.15 EAU93340.2 - 1.9e-132 442.2 0.1 3.1e-132 441.5 0.1 1.3 1 1 0 1 1 1 1 V-ATPase subunit C Cep57_MT_bd PF06657.13 EAU93340.2 - 0.037 14.5 0.1 0.11 12.9 0.1 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF3926 PF13080.6 EAU93340.2 - 0.056 13.4 0.0 14 5.7 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) SRP68 PF16969.5 EAU93341.1 - 5.7e-78 263.3 11.0 4.5e-77 260.3 5.2 2.0 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 ANAPC3 PF12895.7 EAU93341.1 - 0.49 10.7 5.5 0.77 10.0 0.3 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ArsA_ATPase PF02374.15 EAU93342.1 - 2e-111 372.0 1.1 2.3e-111 371.8 1.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EAU93342.1 - 6e-14 52.3 0.1 2.1e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EAU93342.1 - 6.4e-12 45.6 0.0 1.2e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 EAU93342.1 - 7e-06 25.7 0.0 3.1e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EAU93342.1 - 2.2e-05 24.1 0.1 5.7e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EAU93342.1 - 8.1e-05 22.3 0.5 0.0023 17.6 0.1 2.4 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain ParA PF10609.9 EAU93342.1 - 9.2e-05 22.0 5.1 0.0003 20.3 1.4 2.9 1 1 2 3 3 3 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 EAU93342.1 - 0.037 13.6 0.8 0.25 10.9 0.8 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EAU93342.1 - 0.041 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 EAU93342.1 - 0.056 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 EAU93342.1 - 0.061 12.6 0.1 0.14 11.4 0.1 1.6 1 1 0 1 1 1 0 VirC1 protein DNApol_Exo PF18136.1 EAU93343.2 - 1.6e-100 335.9 0.1 7.4e-100 333.7 0.1 2.0 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EAU93343.2 - 1.2e-48 166.1 0.0 2.1e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EAU93343.2 - 0.021 14.5 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease MitoNEET_N PF10660.9 EAU93343.2 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus UvrD_C PF13361.6 EAU93344.2 - 9e-09 35.2 0.0 2e-06 27.4 0.0 3.9 4 0 0 4 4 4 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EAU93344.2 - 3.2e-08 33.5 4.8 9e-08 32.0 0.1 3.2 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EAU93344.2 - 2.6e-06 27.2 0.0 0.0025 17.6 0.0 2.9 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EAU93344.2 - 3.9e-05 24.0 0.0 0.00052 20.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain SNAP PF14938.6 EAU93344.2 - 0.00019 21.0 7.9 0.00044 19.8 7.9 1.5 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP ResIII PF04851.15 EAU93344.2 - 0.0043 17.1 0.4 0.099 12.6 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_12 PF13087.6 EAU93344.2 - 0.01 15.5 0.0 0.029 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EAU93344.2 - 0.024 14.9 1.2 0.11 12.8 0.1 2.7 3 0 0 3 3 3 0 AAA domain ANAPC3 PF12895.7 EAU93344.2 - 0.54 10.5 4.8 0.53 10.6 0.2 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EAU93344.2 - 0.63 11.0 3.5 19 6.4 0.2 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DOT1 PF08123.13 EAU93345.2 - 2.2e-64 216.8 0.0 2.8e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF3398 PF11878.8 EAU93345.2 - 0.063 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) CMAS PF02353.20 EAU93345.2 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ndc80_HEC PF03801.13 EAU93345.2 - 0.17 11.5 0.0 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 HEC/Ndc80p family PBD PF00786.28 EAU93346.1 - 3.4e-18 65.7 0.9 2.7e-10 40.4 0.1 2.5 2 0 0 2 2 2 2 P21-Rho-binding domain PH PF00169.29 EAU93346.1 - 1.7e-15 57.4 0.0 3.4e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 PH domain Chs7 PF12271.8 EAU93347.1 - 1.7e-116 388.6 21.6 2e-116 388.4 21.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cyclin PF08613.11 EAU93350.2 - 3.5e-16 60.0 0.0 1.3e-15 58.1 0.0 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EAU93350.2 - 1.5e-09 37.6 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SPO22 PF08631.10 EAU93351.2 - 3e-54 184.4 3.8 1.2e-37 129.9 0.6 4.0 4 0 0 4 4 4 2 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 EAU93351.2 - 0.00085 19.5 1.0 0.26 11.5 0.2 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 SPOB_a PF14689.6 EAU93351.2 - 0.058 13.1 0.0 1.3 8.8 0.0 2.8 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_14 PF13428.6 EAU93351.2 - 0.17 12.8 4.3 31 5.7 0.2 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU93351.2 - 3.3 8.1 4.7 72 3.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4965 PF16335.5 EAU93352.2 - 3.6e-49 166.8 0.0 5.8e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EAU93352.2 - 3e-24 86.1 0.1 7.5e-24 84.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EAU93352.2 - 6.5e-23 82.0 0.1 1e-22 81.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Syndecan PF01034.20 EAU93352.2 - 0.049 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain TRAPP PF04051.16 EAU93354.1 - 3.2e-34 117.8 0.0 4.1e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SR-25 PF10500.9 EAU93355.1 - 0.0066 16.1 5.0 0.01 15.5 5.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CPSF100_C PF13299.6 EAU93355.1 - 0.11 12.7 1.7 0.14 12.4 1.2 1.4 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4360 PF14273.6 EAU93357.1 - 8.1e-29 100.7 3.5 9.7e-29 100.5 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.6 EAU93358.1 - 1.6e-24 86.7 0.1 2.5e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PCI PF01399.27 EAU93360.2 - 1.7e-05 25.2 0.6 4.7e-05 23.8 0.6 1.7 1 1 0 1 1 1 1 PCI domain Mce4_CUP1 PF11887.8 EAU93360.2 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative CSN7a_helixI PF18392.1 EAU93360.2 - 0.0057 16.5 0.4 0.011 15.6 0.4 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain HAUS-augmin3 PF14932.6 EAU93360.2 - 0.011 15.3 1.8 0.019 14.5 1.8 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF5595 PF18077.1 EAU93360.2 - 0.054 13.6 0.1 0.93 9.6 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) PSP1 PF04468.12 EAU93361.2 - 9e-32 109.2 0.7 1.7e-31 108.4 0.7 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-ANAPC11 PF12861.7 EAU93362.1 - 5.9e-40 135.2 13.0 7.5e-40 134.9 13.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EAU93362.1 - 9.6e-22 77.0 13.2 1.5e-21 76.4 13.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EAU93362.1 - 0.00015 22.0 16.9 0.003 17.9 17.0 2.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EAU93362.1 - 0.0075 16.3 9.7 0.024 14.7 9.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EAU93362.1 - 0.092 12.7 14.0 1.5 8.9 14.6 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EAU93362.1 - 0.29 11.0 15.1 1.6 8.7 15.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EAU93362.1 - 2.4 8.4 16.8 18 5.6 16.8 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EAU93362.1 - 3.5 7.5 13.9 18 5.2 13.9 2.1 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EAU93362.1 - 9.1 6.0 23.0 0.39 10.4 14.6 2.5 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type Glyco_transf_25 PF01755.17 EAU93363.1 - 5.6e-10 39.4 0.0 1.1e-05 25.4 0.0 2.8 3 1 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Metal_resist PF13801.6 EAU93363.1 - 0.34 11.1 5.3 0.12 12.6 1.6 2.1 2 0 0 2 2 2 0 Heavy-metal resistance Syntaxin-6_N PF09177.11 EAU93363.1 - 0.69 10.5 5.4 0.85 10.2 1.3 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FKBP_C PF00254.28 EAU93364.2 - 1.7e-20 73.1 0.0 2e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mem_trans PF03547.18 EAU93365.2 - 8.8e-32 110.0 8.5 2.2e-19 69.2 5.7 3.8 3 1 0 3 3 3 3 Membrane transport protein Cation_efflux PF01545.21 EAU93365.2 - 0.034 13.9 1.3 0.13 12.0 0.4 2.2 3 0 0 3 3 3 0 Cation efflux family PhoLip_ATPase_C PF16212.5 EAU93365.2 - 3.6 7.3 10.4 2.6 7.7 3.1 2.3 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Methyltransf_31 PF13847.6 EAU93366.1 - 5.6e-16 58.7 0.0 7.2e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EAU93366.1 - 1.4e-14 54.2 0.2 5.4e-14 52.4 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU93366.1 - 8.7e-14 52.0 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EAU93366.1 - 1.3e-13 51.4 0.0 2.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU93366.1 - 8.8e-12 45.6 0.0 1.7e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU93366.1 - 1.1e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EAU93366.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EAU93366.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EAU93366.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EAU93366.1 - 0.021 14.8 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 EAU93366.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CheR PF01739.18 EAU93366.1 - 0.049 13.1 0.0 1.5 8.3 0.0 2.2 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 EAU93366.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Pkinase_fungal PF17667.1 EAU93367.2 - 1.2e-66 225.2 0.0 3.1e-66 223.8 0.0 1.6 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EAU93367.2 - 0.0023 17.9 0.1 0.018 15.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EAU93367.2 - 0.0027 17.1 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EAU93367.2 - 0.078 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex14_N PF04695.13 EAU93367.2 - 0.41 11.3 16.9 1.6 9.3 15.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 EAU93367.2 - 1 9.2 4.7 1.7 8.4 4.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lin-8 PF03353.15 EAU93367.2 - 2.2 7.8 8.9 4.9 6.6 8.9 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 EAU93367.2 - 6.1 7.0 5.3 14 5.9 5.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal adh_short_C2 PF13561.6 EAU93368.2 - 6e-52 176.5 0.7 3.8e-51 173.9 0.7 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EAU93368.2 - 1.1e-43 149.0 0.1 1.4e-43 148.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EAU93368.2 - 8.6e-14 51.8 0.1 1.2e-13 51.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EAU93368.2 - 0.0019 18.9 0.0 0.0033 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 3HCDH_N PF02737.18 EAU93368.2 - 0.046 13.6 0.1 0.079 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Caleosin PF05042.13 EAU93369.2 - 9.4e-56 188.4 0.3 1.2e-55 188.0 0.3 1.1 1 0 0 1 1 1 1 Caleosin related protein Pkinase_fungal PF17667.1 EAU93371.2 - 5.2e-45 153.9 0.0 1.7e-39 135.8 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EAU93371.2 - 0.0031 16.9 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU93371.2 - 0.0048 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EAU93371.2 - 0.054 13.1 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pex14_N PF04695.13 EAU93371.2 - 0.19 12.4 12.2 0.95 10.1 10.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 EAU93371.2 - 1.2 8.7 4.0 1.9 7.9 4.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC53 PF10152.9 EAU93371.2 - 2.4 8.6 8.7 7.1 7.0 8.7 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 EAU93371.2 - 3.7 7.1 11.2 6.7 6.3 11.2 1.3 1 0 0 1 1 1 0 Spt20 family Pkinase_fungal PF17667.1 EAU93372.1 - 2.8e-46 158.1 0.0 5.2e-46 157.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase N6-adenineMlase PF10237.9 EAU93373.1 - 5e-44 149.9 0.1 6.8e-44 149.5 0.1 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 EAU93373.1 - 0.014 15.0 0.0 0.047 13.3 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical protein 95 Formyl_trans_N PF00551.19 EAU93374.2 - 3.5e-42 144.2 0.1 6.5e-21 74.9 0.0 2.0 2 0 0 2 2 2 2 Formyl transferase Pkinase PF00069.25 EAU93375.2 - 2.5e-29 102.4 0.0 3.5e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93375.2 - 2.2e-13 50.1 0.0 3.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU93375.2 - 0.00018 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EAU93375.2 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L19e PF01280.20 EAU93376.1 - 2.8e-59 199.3 11.5 2.8e-59 199.3 11.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 EAU93376.1 - 0.01 15.5 0.0 0.039 13.7 0.0 2.0 1 0 0 1 1 1 0 S4 domain Pkinase PF00069.25 EAU93377.2 - 3.2e-54 184.1 0.0 3.9e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93377.2 - 1.6e-22 80.0 0.0 2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU93377.2 - 0.00016 21.1 0.0 0.00037 19.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 EAU93378.2 - 3.2e-34 118.5 0.0 5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93378.2 - 6.9e-17 61.6 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU93378.2 - 8.2e-05 22.1 0.0 0.0002 20.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like SRP54_N PF02881.19 EAU93378.2 - 0.2 11.9 0.3 0.4 10.9 0.3 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain DUF4470 PF14737.6 EAU93379.1 - 8.2e-12 45.2 0.0 2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EAU93379.1 - 3e-05 23.8 2.1 0.011 15.8 1.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EAU93379.1 - 0.09 12.6 1.9 2.1 8.3 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SOG2 PF10428.9 EAU93380.1 - 0.24 10.6 22.2 0.28 10.3 22.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Rgp1 PF08737.10 EAU93381.2 - 3.4e-51 174.8 0.1 6.6e-51 173.8 0.1 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EAU93381.2 - 0.00037 20.6 0.0 0.021 14.9 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EAU93381.2 - 0.00057 20.3 0.0 0.22 12.0 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain CAP_N PF01213.19 EAU93383.1 - 4 6.8 5.6 4.9 6.5 5.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Trm112p PF03966.16 EAU93388.1 - 9.3e-21 74.2 0.1 1.1e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein PhnA_Zn_Ribbon PF08274.12 EAU93388.1 - 0.0045 16.9 0.2 0.0093 15.9 0.2 1.6 1 0 0 1 1 1 1 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.6 EAU93388.1 - 0.023 14.1 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 EAU93388.1 - 0.024 14.3 0.2 0.046 13.4 0.2 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-RING_4 PF14570.6 EAU93388.1 - 0.032 14.0 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ACC PF17848.1 EAU93388.1 - 0.05 13.7 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-UDP PF14569.6 EAU93388.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger Pkinase_fungal PF17667.1 EAU93389.1 - 2.2e-47 161.8 0.0 4.3e-47 160.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Gluconate_2-dh3 PF13618.6 EAU93389.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Pkinase_fungal PF17667.1 EAU93390.2 - 6.6e-66 222.8 0.0 9.9e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EAU93390.2 - 0.0033 16.8 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EAU93390.2 - 0.033 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CPSF100_C PF13299.6 EAU93390.2 - 0.64 10.2 2.8 1.3 9.2 2.8 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.13 EAU93390.2 - 1.8 9.2 6.3 7.4 7.2 5.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MOZ_SAS PF01853.18 EAU93391.2 - 4.5e-58 195.9 0.2 1.8e-57 193.9 0.1 1.8 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 EAU93391.2 - 2.5e-16 59.0 0.3 4.9e-08 32.5 0.1 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 EAU93391.2 - 4.4e-06 26.5 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EAU93391.2 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EAU93391.2 - 0.0043 17.3 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family F-box-like PF12937.7 EAU93396.1 - 5.4e-06 26.2 1.7 1.4e-05 24.8 1.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU93396.1 - 0.033 14.1 0.2 0.1 12.5 0.2 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EAU93397.1 - 8.9e-07 28.7 1.3 3.6e-06 26.8 0.4 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU93397.1 - 0.07 13.0 0.0 0.56 10.1 0.0 2.5 2 1 0 2 2 2 0 F-box domain Mpv17_PMP22 PF04117.12 EAU93398.1 - 1.1e-23 83.2 0.1 2.3e-23 82.2 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family ATP-synt_Z PF16594.5 EAU93398.1 - 0.032 13.7 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated SpoIIIAH PF12685.7 EAU93399.1 - 0.052 13.4 6.3 0.088 12.6 6.3 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Oleosin PF01277.17 EAU93399.1 - 0.1 12.4 2.2 0.96 9.2 0.0 2.6 1 1 1 2 2 2 0 Oleosin DUF2477 PF10631.9 EAU93399.1 - 0.3 11.8 3.1 0.39 11.4 2.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) Peptidase_S15 PF02129.18 EAU93399.1 - 0.45 10.1 4.8 0.6 9.6 4.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SpoV PF08183.11 EAU93399.1 - 0.98 9.4 2.5 2.2 8.3 2.5 1.6 1 0 0 1 1 1 0 Stage V sporulation protein family DDHD PF02862.17 EAU93399.1 - 2.7 8.1 6.4 3.8 7.6 6.4 1.2 1 0 0 1 1 1 0 DDHD domain TMEM43 PF07787.12 EAU93399.1 - 7.4 5.9 7.2 3.5 6.9 2.0 2.4 2 1 1 3 3 3 0 Transmembrane protein 43 DUF883 PF05957.13 EAU93399.1 - 8.6 7.0 14.7 9.7 6.9 10.9 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.7 EAU93400.2 - 5.4e-08 32.6 1.4 2.7e-07 30.4 1.4 2.3 1 1 0 1 1 1 1 F-box-like EBV-NA3 PF05009.12 EAU93400.2 - 0.016 14.7 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) F-box-like_2 PF13013.6 EAU93400.2 - 0.067 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain CBS PF00571.28 EAU93401.2 - 5.5e-34 116.4 7.4 1.7e-09 38.0 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EAU93401.2 - 9.5e-08 31.9 0.0 2.2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Pkinase PF00069.25 EAU93402.1 - 3.4e-52 177.4 0.0 2.4e-51 174.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93402.1 - 1.8e-38 132.3 0.0 5.6e-23 81.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EAU93402.1 - 4.1e-06 25.8 0.0 7.5e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EAU93402.1 - 0.13 11.6 0.1 0.27 10.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like MitMem_reg PF13012.6 EAU93403.2 - 3.1e-26 92.0 0.1 5.3e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EAU93403.2 - 1.5e-12 47.5 0.0 2.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MCM PF00493.23 EAU93404.1 - 2.8e-104 347.1 0.1 7.8e-104 345.6 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EAU93404.1 - 1.5e-33 115.3 0.1 3.6e-33 114.1 0.0 1.6 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EAU93404.1 - 7.2e-29 100.1 1.8 1.6e-28 98.9 1.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EAU93404.1 - 1.7e-16 60.7 0.1 4.6e-16 59.3 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EAU93404.1 - 7.8e-07 28.7 0.0 0.00025 20.5 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EAU93404.1 - 3.5e-05 23.8 0.0 8.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EAU93404.1 - 0.00049 20.0 0.1 0.0028 17.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EAU93404.1 - 0.042 14.5 0.9 0.65 10.7 0.3 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 EAU93404.1 - 0.098 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNase_T PF00929.24 EAU93405.2 - 6.3e-07 30.1 0.0 9.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease BATS PF06968.13 EAU93406.2 - 4.8e-23 81.1 0.3 1.7e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EAU93406.2 - 1.6e-17 64.4 0.0 2.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily BTG PF07742.12 EAU93408.1 - 5.9e-15 55.1 0.0 1.1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 BTG family RAP1 PF07218.11 EAU93408.1 - 1.7 6.8 7.9 2.6 6.2 7.9 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S27e PF01667.17 EAU93409.1 - 2e-29 101.0 5.3 2.4e-29 100.8 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 EAU93409.1 - 0.011 16.0 1.0 0.014 15.6 1.0 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 EAU93409.1 - 0.019 14.5 2.5 0.028 13.9 2.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 EAU93409.1 - 1 9.4 7.0 0.44 10.6 3.9 2.0 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-C2H2 PF00096.26 EAU93411.1 - 1.7e-08 34.5 19.7 2.2e-06 27.8 0.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU93411.1 - 9.2e-07 29.2 15.0 0.00075 20.1 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU93411.1 - 0.00087 19.6 12.0 0.052 14.0 2.3 3.6 3 1 0 3 3 3 2 Zinc-finger double domain zf_ZIC PF18366.1 EAU93411.1 - 0.0022 18.1 1.3 0.91 9.7 0.5 2.4 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 EAU93411.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EAU93411.1 - 0.027 14.7 6.0 0.031 14.6 0.4 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding C1_2 PF03107.16 EAU93411.1 - 0.03 14.6 1.3 7.2 7.0 0.5 2.5 2 0 0 2 2 2 0 C1 domain zf-H2C2_5 PF13909.6 EAU93411.1 - 0.21 11.4 4.9 0.61 9.9 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.7 EAU93411.1 - 1.1 9.7 7.5 0.83 10.1 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EAU93411.1 - 5.3 6.9 13.2 8.5 6.2 5.4 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type Med6 PF04934.14 EAU93412.2 - 4.4e-39 133.3 0.2 7e-39 132.7 0.2 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Clat_adaptor_s PF01217.20 EAU93413.1 - 2.4e-38 131.2 0.0 1.8e-32 112.2 0.2 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain SGT1 PF07093.11 EAU93414.2 - 2.2e-88 297.2 15.2 4.7e-56 190.4 0.1 4.1 3 2 0 4 4 4 3 SGT1 protein ATP-synt_F PF01990.17 EAU93415.1 - 2.4e-32 111.1 0.2 2.8e-32 110.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 EAU93415.1 - 0.089 12.0 0.0 0.089 12.0 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TIM21 PF08294.11 EAU93416.2 - 2.7e-21 76.0 0.0 2.2e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 TIM21 Histone PF00125.24 EAU93417.1 - 2.6e-49 166.9 3.9 3e-49 166.7 3.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EAU93417.1 - 2.6e-05 24.5 0.1 4.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EAU93417.1 - 5.3e-05 23.3 0.1 0.0001 22.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EAU93417.1 - 0.00024 21.7 2.2 0.0003 21.4 2.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EAU93417.1 - 0.00073 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EAU93417.1 - 0.088 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EAU93417.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PhyH PF05721.13 EAU93418.2 - 0.00015 22.1 0.1 0.0036 17.6 0.1 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Chalcone_2 PF16035.5 EAU93419.1 - 2.5e-27 96.0 0.1 5.8e-16 58.9 0.0 2.4 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 EAU93419.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.4 1 1 0 1 1 1 0 Chalcone isomerase-like zf-CCCH PF00642.24 EAU93423.1 - 7e-19 67.3 14.1 8.6e-11 41.5 2.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EAU93423.1 - 3.8e-09 36.1 11.3 3.4e-06 26.7 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EAU93423.1 - 6.1e-09 35.6 13.8 2.1e-06 27.6 3.9 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 EAU93423.1 - 0.026 15.0 8.3 0.087 13.3 0.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EAU93423.1 - 0.056 14.1 9.3 0.66 10.7 1.6 2.7 1 1 1 2 2 2 0 Torus domain Choline_kinase PF01633.20 EAU93424.2 - 6.8e-52 176.1 0.0 9.7e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EAU93424.2 - 2.3e-11 44.1 0.0 3.9e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EAU93424.2 - 0.083 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.16 EAU93425.2 - 8.5e-39 133.5 53.1 1.6e-37 129.2 53.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU93425.2 - 1.9e-09 36.9 13.5 1.9e-09 36.9 13.5 2.8 2 2 1 3 3 3 1 Sugar (and other) transporter DUF983 PF06170.12 EAU93425.2 - 0.44 11.0 3.6 0.59 10.6 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DnaJ_C PF01556.18 EAU93426.2 - 1.4e-38 132.3 0.0 1.8e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EAU93426.2 - 6.3e-24 83.9 2.5 9.6e-24 83.3 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EAU93426.2 - 1.1e-07 32.1 19.1 1.1e-07 32.1 19.1 2.0 2 0 0 2 2 2 1 DnaJ central domain SSP160 PF06933.11 EAU93426.2 - 4.9 5.2 11.2 6.7 4.8 11.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SR-25 PF10500.9 EAU93426.2 - 6.6 6.3 21.7 11 5.5 21.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 EAU93427.2 - 5.1e-64 216.2 0.2 6.9e-64 215.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93427.2 - 4.5e-20 72.0 0.0 6.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EAU93427.2 - 1.8e-06 28.1 0.1 4.3e-05 23.6 0.2 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EAU93427.2 - 0.008 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EAU93427.2 - 0.026 14.1 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EAU93427.2 - 0.059 12.7 0.4 0.13 11.6 0.4 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_18 PF00704.28 EAU93428.2 - 3.4e-22 79.6 1.8 9.4e-22 78.1 1.8 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12_2 PF14600.6 EAU93428.2 - 0.00012 22.0 11.3 0.039 13.9 2.5 2.9 2 0 0 2 2 2 2 Cellulose-binding domain CBM_5_12 PF02839.14 EAU93428.2 - 0.0079 16.7 2.3 0.0079 16.7 2.3 3.7 3 0 0 3 3 3 1 Carbohydrate binding domain Mucin PF01456.17 EAU93428.2 - 0.063 13.3 22.5 0.12 12.4 22.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Mito_fiss_reg PF05308.11 EAU93428.2 - 4.5 7.3 4.3 7 6.6 4.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SSP160 PF06933.11 EAU93428.2 - 5.7 5.0 19.9 9.4 4.3 19.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 EAU93428.2 - 8.3 6.9 11.6 23 5.4 11.6 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DNA_pol_A_exo1 PF01612.20 EAU93429.2 - 9.2e-15 54.8 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-RING_2 PF13639.6 EAU93431.2 - 4.2e-05 23.8 5.9 4.2e-05 23.8 5.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EAU93431.2 - 5.8e-05 22.9 3.6 5.8e-05 22.9 3.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EAU93431.2 - 0.00011 22.0 4.3 0.00011 22.0 4.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EAU93431.2 - 0.00031 20.5 2.0 0.00097 18.9 2.0 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EAU93431.2 - 0.00099 18.9 5.8 0.00099 18.9 5.8 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EAU93431.2 - 0.0013 18.6 4.2 0.0028 17.5 4.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EAU93431.2 - 0.011 15.8 5.2 0.031 14.3 5.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EAU93431.2 - 0.017 15.1 3.7 0.017 15.1 3.7 2.4 3 0 0 3 3 3 0 zinc-RING finger domain DZR PF12773.7 EAU93431.2 - 0.027 14.5 2.8 0.027 14.5 2.8 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 EAU93431.2 - 1.4 9.2 5.5 3.5 7.9 5.3 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DcpS_C PF11969.8 EAU93435.2 - 0.00015 22.2 1.1 0.00062 20.2 1.1 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF3875 PF12991.7 EAU93435.2 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3875) DUF5427 PF10310.9 EAU93439.1 - 3.2e-64 217.6 14.7 4.1e-62 210.6 7.9 2.2 1 1 1 2 2 2 2 Family of unknown function (DUF5427) Ndc1_Nup PF09531.10 EAU93439.1 - 0.094 11.4 2.9 0.17 10.6 2.9 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Complex1_30kDa PF00329.19 EAU93440.2 - 3.3e-47 160.1 0.0 4.7e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.11 EAU93441.1 - 4.5e-70 235.5 9.6 5.1e-70 235.4 9.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 EAU93441.1 - 0.0021 18.0 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor LRR_RI_capping PF18779.1 EAU93441.1 - 0.093 12.4 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat GvpK PF05121.12 EAU93441.1 - 0.11 12.6 2.8 0.26 11.3 2.4 1.9 1 1 0 1 1 1 0 Gas vesicle protein K APG6_N PF17675.1 EAU93441.1 - 0.88 10.1 15.4 0.11 13.0 9.8 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region NARP1 PF12569.8 EAU93442.2 - 2.3 7.0 8.1 3.7 6.3 8.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 4HBT_3 PF13622.6 EAU93444.2 - 8.9e-42 144.0 0.0 1.2e-41 143.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EAU93444.2 - 9e-17 61.2 0.0 4.2e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA thioesterase RXT2_N PF08595.11 EAU93445.1 - 0.26 11.3 1.6 1.8 8.6 0.0 2.4 1 1 1 2 2 2 0 RXT2-like, N-terminal ATP-grasp_2 PF08442.10 EAU93446.2 - 7.2e-72 241.2 1.6 7.9e-72 241.1 0.6 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EAU93446.2 - 4.3e-27 94.8 0.1 1.1e-26 93.5 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EAU93446.2 - 8.8e-11 41.7 0.7 4.9e-10 39.3 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EAU93446.2 - 0.00012 21.9 0.1 0.00036 20.3 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PASTA PF03793.19 EAU93446.2 - 0.015 15.2 0.1 9 6.2 0.0 2.9 2 0 0 2 2 2 0 PASTA domain DinB_2 PF12867.7 EAU93447.2 - 1.7e-06 28.6 0.3 2.1e-06 28.3 0.3 1.2 1 0 0 1 1 1 1 DinB superfamily Rogdi_lz PF10259.9 EAU93447.2 - 0.011 15.2 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Hist_deacetyl PF00850.19 EAU93448.2 - 8.3e-86 288.2 0.0 1.1e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Tim17 PF02466.19 EAU93449.1 - 5.7e-14 52.4 0.2 1.1e-13 51.6 0.2 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EAU93449.1 - 0.13 12.4 1.8 13 6.0 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5518) SLD3 PF08639.10 EAU93449.1 - 0.24 10.1 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Ras PF00071.22 EAU93451.2 - 1e-43 148.7 0.1 1.5e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EAU93451.2 - 9.5e-15 54.9 0.0 8e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EAU93451.2 - 0.00033 20.3 0.0 0.00099 18.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EAU93451.2 - 0.0025 17.3 0.1 0.12 11.8 0.0 2.7 1 1 2 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EAU93451.2 - 0.0033 17.3 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EAU93451.2 - 0.083 13.3 0.4 0.22 11.9 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EAU93451.2 - 0.084 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein She2p PF11435.8 EAU93451.2 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 2 0 0 2 2 2 0 RNA binding protein She2p AAA_24 PF13479.6 EAU93451.2 - 0.14 11.8 0.0 0.34 10.6 0.0 1.7 2 1 0 2 2 2 0 AAA domain Yippee-Mis18 PF03226.14 EAU93453.2 - 2.2e-10 40.7 1.1 3.3e-10 40.1 1.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EAU93453.2 - 0.2 11.9 0.9 0.32 11.2 0.9 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I Peptidase_C48 PF02902.19 EAU93455.2 - 1e-33 117.0 0.1 1.8e-33 116.3 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ANAPC9 PF12856.7 EAU93455.2 - 0.14 12.4 0.5 0.34 11.1 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 LacI PF00356.21 EAU93455.2 - 0.18 11.6 0.0 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF2724 PF10893.8 EAU93456.1 - 0.069 13.0 0.1 0.39 10.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2724) SUR7 PF06687.12 EAU93457.1 - 0.02 14.6 0.7 0.02 14.6 0.7 2.1 2 0 0 2 2 2 0 SUR7/PalI family DUF2254 PF10011.9 EAU93457.1 - 5.8 5.6 9.9 1.5 7.5 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2254) 4HBT_3 PF13622.6 EAU93458.1 - 5.1e-24 85.9 0.6 7.4e-24 85.3 0.6 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Beta_elim_lyase PF01212.21 EAU93459.1 - 4.3e-74 249.4 0.0 6.6e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EAU93459.1 - 9.9e-06 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EAU93459.1 - 0.0045 15.6 0.0 0.006 15.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EAU93459.1 - 0.011 15.1 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 EAU93459.1 - 0.052 12.3 0.2 0.078 11.7 0.2 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Nbs1_C PF08599.10 EAU93459.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 zf-met2 PF12907.7 EAU93460.1 - 5.3e-16 58.5 2.8 7.5e-16 58.0 2.8 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EAU93460.1 - 9.7e-07 29.6 7.9 9.7e-07 29.6 7.9 1.7 2 0 0 2 2 2 1 4F5 protein family ANAPC4_WD40 PF12894.7 EAU93462.1 - 2.8e-10 40.3 0.1 0.001 19.3 0.0 5.8 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EAU93462.1 - 6e-08 33.2 19.5 0.75 10.8 0.0 7.8 8 0 0 8 8 8 3 WD domain, G-beta repeat BAT PF15915.5 EAU93462.1 - 0.021 14.7 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 GAF and HTH_10 associated domain PD40 PF07676.12 EAU93462.1 - 0.037 14.0 0.1 10 6.2 0.0 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SIN1 PF05422.12 EAU93462.1 - 0.071 13.7 2.7 0.096 13.2 0.0 2.3 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) DUF2632 PF10943.8 EAU93462.1 - 0.099 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) FAM176 PF14851.6 EAU93462.1 - 1.8 8.2 7.7 2.2 7.9 0.2 3.0 3 0 0 3 3 3 0 FAM176 family DUF3246 PF11596.8 EAU93462.1 - 2.9 7.2 8.4 1.3 8.5 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF3245 PF11595.8 EAU93462.1 - 3.8 8.0 7.8 2.7 8.4 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) F-box-like PF12937.7 EAU93463.1 - 3.3e-11 42.9 0.3 7.2e-11 41.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU93463.1 - 0.0049 16.7 2.4 0.22 11.5 0.3 2.6 2 0 0 2 2 2 2 F-box domain zf-C2H2_3 PF13878.6 EAU93464.2 - 4.4 7.2 7.7 16 5.4 0.5 3.2 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO AAA_19 PF13245.6 EAU93466.1 - 0.092 13.1 0.0 0.11 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.23 EAU93468.1 - 2.9e-40 138.2 0.0 1.5e-39 135.9 0.0 2.1 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EAU93468.1 - 2.2e-19 69.0 0.3 7.1e-19 67.4 0.1 2.0 1 1 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EAU93468.1 - 9.6e-11 41.9 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EAU93468.1 - 0.017 14.9 0.1 0.15 11.9 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Med21 PF11221.8 EAU93470.1 - 2.2e-26 92.8 5.7 3.4e-26 92.2 5.7 1.3 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DEAD PF00270.29 EAU93471.1 - 4e-12 46.2 0.0 5.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EAU93471.1 - 0.00079 19.5 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ifi-6-16 PF06140.13 EAU93472.1 - 2e-06 27.6 20.0 3.8e-06 26.7 20.0 1.6 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 EAU93473.1 - 7.5e-06 25.8 10.5 7.5e-06 25.8 10.5 2.1 1 1 1 2 2 2 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 EAU93474.1 - 6.3e-05 22.8 21.6 6.3e-05 22.8 21.6 2.8 4 1 0 4 4 4 1 Interferon-induced 6-16 family TMEM214 PF10151.9 EAU93474.1 - 0.028 12.9 0.3 0.035 12.6 0.3 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF883 PF05957.13 EAU93474.1 - 1.8 9.2 10.8 0.56 10.8 5.2 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) REF PF05755.12 EAU93474.1 - 2.3 8.0 8.4 1.9 8.3 6.6 1.7 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) Ifi-6-16 PF06140.13 EAU93475.1 - 2.4e-06 27.3 19.2 2.4e-06 27.3 19.2 2.9 3 0 0 3 3 3 1 Interferon-induced 6-16 family TMEM214 PF10151.9 EAU93475.1 - 0.0069 14.9 1.8 0.041 12.3 1.8 2.0 1 1 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator DUF885 PF05960.11 EAU93475.1 - 0.19 11.3 15.7 0.18 11.4 4.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF885) ANAPC4_WD40 PF12894.7 EAU93477.2 - 0.0002 21.6 0.0 2.9 8.2 0.0 4.2 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 EAU93477.2 - 0.057 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) HrpB7 PF09486.10 EAU93477.2 - 1.5 9.2 7.8 0.14 12.5 3.1 1.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Rtf2 PF04641.12 EAU93478.2 - 7.5e-74 248.4 3.5 9.3e-74 248.1 3.5 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zinc_ribbon_15 PF17032.5 EAU93478.2 - 0.039 14.7 0.2 0.098 13.4 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon family RE_MamI PF09567.10 EAU93478.2 - 0.1 12.2 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 MamI restriction endonuclease zf-UDP PF14569.6 EAU93478.2 - 0.32 11.2 3.0 0.89 9.7 2.2 2.2 1 1 0 1 1 1 0 Zinc-binding RING-finger Menin PF05053.13 EAU93478.2 - 9.3 4.5 8.1 1.9 6.8 2.8 1.8 1 1 0 1 1 1 0 Menin MMR_HSR1 PF01926.23 EAU93479.1 - 6.9e-09 35.8 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EAU93479.1 - 0.00014 21.8 0.0 0.00058 19.8 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EAU93479.1 - 0.00022 20.7 0.0 0.0014 18.0 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EAU93479.1 - 0.001 19.2 0.0 0.57 10.2 0.0 2.6 2 0 0 2 2 2 2 Dynamin family AAA_33 PF13671.6 EAU93479.1 - 0.01 16.0 0.0 0.055 13.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain Septin PF00735.18 EAU93479.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 EAU93479.1 - 0.024 14.9 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EAU93479.1 - 0.18 11.6 0.0 6.2 6.6 0.0 2.3 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Pollen_allerg_2 PF01620.16 EAU93480.2 - 0.02 15.1 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) CCAP PF11105.8 EAU93480.2 - 0.096 12.6 0.2 0.23 11.4 0.1 1.6 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a ChpA-C PF03777.13 EAU93480.2 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 ChpA-C PGM_PMM_IV PF00408.20 EAU93480.2 - 0.13 12.5 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain MMR_HSR1 PF01926.23 EAU93481.2 - 5.3e-08 32.9 0.0 9.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU93481.2 - 4.4e-06 26.9 0.1 0.00043 20.4 0.0 2.3 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EAU93481.2 - 0.00041 20.3 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 EAU93481.2 - 0.0034 16.5 0.0 0.0081 15.3 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EAU93481.2 - 0.0079 16.5 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain Septin PF00735.18 EAU93481.2 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 EAU93481.2 - 0.015 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF732 PF05305.14 EAU93481.2 - 0.044 14.2 0.0 0.081 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF732) AAA_16 PF13191.6 EAU93481.2 - 0.057 13.8 0.1 0.16 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EAU93481.2 - 0.062 13.8 0.1 0.093 13.2 0.1 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EAU93481.2 - 0.098 12.6 0.4 11 5.9 0.1 2.7 3 0 0 3 3 3 0 NACHT domain DUF87 PF01935.17 EAU93481.2 - 0.29 11.2 0.6 0.67 10.0 0.2 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EAU93483.1 - 3.6e-10 39.9 0.0 8.5e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EAU93483.1 - 3.2e-06 26.6 0.0 6.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EAU93483.1 - 1.2e-05 25.5 0.1 3.2e-05 24.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EAU93483.1 - 2.4e-05 24.3 0.0 6.9e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EAU93483.1 - 0.00033 20.8 2.5 0.017 15.2 0.0 2.9 1 1 3 4 4 4 1 Dynamin family AIG1 PF04548.16 EAU93483.1 - 0.001 18.4 0.6 0.0019 17.6 0.1 1.6 1 1 1 2 2 2 1 AIG1 family SRPRB PF09439.10 EAU93483.1 - 0.0017 17.8 2.0 0.0021 17.6 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EAU93483.1 - 0.0031 17.1 0.8 0.023 14.3 0.8 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EAU93483.1 - 0.0032 17.7 0.1 0.0081 16.4 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EAU93483.1 - 0.0033 17.4 0.1 0.014 15.3 0.1 2.0 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 EAU93483.1 - 0.0038 17.4 0.1 0.0038 17.4 0.1 2.1 2 2 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EAU93483.1 - 0.0052 16.6 2.7 0.48 10.2 0.1 2.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein VirE PF05272.11 EAU93483.1 - 0.0069 16.1 0.2 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E AAA_7 PF12775.7 EAU93483.1 - 0.0094 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 EAU93483.1 - 0.011 15.0 0.4 0.027 13.8 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 EAU93483.1 - 0.019 15.4 0.1 0.065 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EAU93483.1 - 0.028 15.0 0.5 0.13 12.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EAU93483.1 - 0.03 14.8 0.6 0.15 12.5 0.0 2.1 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.12 EAU93483.1 - 0.03 14.2 0.4 1.6 8.6 0.1 2.5 1 1 1 2 2 2 0 NACHT domain AAA_29 PF13555.6 EAU93483.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EAU93483.1 - 0.034 14.2 0.0 0.74 9.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAU93483.1 - 0.053 13.2 0.8 0.14 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EAU93483.1 - 0.08 13.3 0.3 0.27 11.7 0.3 2.0 1 1 0 1 1 1 0 RNA helicase DNA_pol3_delta2 PF13177.6 EAU93483.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF2205 PF10224.9 EAU93483.1 - 0.62 10.1 6.2 1.1 9.3 0.9 2.7 2 0 0 2 2 2 0 Short coiled-coil protein AAA_23 PF13476.6 EAU93483.1 - 1.6 9.2 0.0 1.6 9.2 0.0 2.4 2 1 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 EAU93484.2 - 5.4e-11 42.6 0.0 8.5e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU93484.2 - 3.8e-08 33.6 0.0 0.0021 18.1 0.0 2.3 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EAU93484.2 - 8.1e-07 28.6 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 EAU93484.2 - 1.2e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 EAU93484.2 - 0.00057 19.8 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 EAU93484.2 - 0.017 14.5 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 EAU93484.2 - 0.053 14.0 0.0 0.092 13.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EAU93484.2 - 0.068 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Spore_IV_A PF09547.10 EAU93484.2 - 0.077 11.9 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) IIGP PF05049.13 EAU93484.2 - 0.096 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.10 EAU93484.2 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit GBP PF02263.19 EAU93484.2 - 0.16 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Roc PF08477.13 EAU93484.2 - 0.17 12.1 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EAU93485.2 - 1.3e-09 38.1 0.0 2.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU93485.2 - 7.8e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 EAU93485.2 - 3.4e-05 23.3 0.0 6.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EAU93485.2 - 4.7e-05 23.5 0.0 0.53 10.3 0.0 2.9 3 1 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EAU93485.2 - 0.00011 22.2 0.1 0.00096 19.1 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase IIGP PF05049.13 EAU93485.2 - 0.00054 19.1 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EAU93485.2 - 0.0016 19.0 0.1 0.0043 17.6 0.0 1.8 2 1 0 2 2 2 1 ABC transporter Spore_IV_A PF09547.10 EAU93485.2 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) KAP_NTPase PF07693.14 EAU93485.2 - 0.015 14.6 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 EAU93485.2 - 0.016 15.4 0.0 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3450 PF11932.8 EAU93485.2 - 0.023 14.0 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_23 PF13476.6 EAU93485.2 - 0.03 14.8 0.4 0.76 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EAU93485.2 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 EAU93485.2 - 0.075 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EAU93485.2 - 0.089 12.1 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 EAU93485.2 - 0.091 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 EAU93485.2 - 0.11 12.5 0.5 0.3 11.1 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain Sigma54_activat PF00158.26 EAU93485.2 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EAU93485.2 - 0.16 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FlxA PF14282.6 EAU93485.2 - 1 9.4 4.4 3.2 7.8 4.4 1.8 1 1 0 1 1 1 0 FlxA-like protein MMR_HSR1 PF01926.23 EAU93486.2 - 3.3e-14 52.9 0.9 2.8e-08 33.8 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 EAU93486.2 - 2.2e-08 34.3 5.1 0.041 13.9 0.0 4.2 4 0 0 4 4 4 2 Dynamin family RsgA_GTPase PF03193.16 EAU93486.2 - 4.8e-07 29.8 0.3 0.0018 18.2 0.1 2.7 2 1 0 2 2 2 2 RsgA GTPase Septin PF00735.18 EAU93486.2 - 1.3e-06 28.0 0.1 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 EAU93486.2 - 2.1e-05 25.0 0.0 0.0041 17.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EAU93486.2 - 2.3e-05 23.8 4.7 0.0062 15.9 0.1 3.5 4 0 0 4 4 4 2 AIG1 family AAA_29 PF13555.6 EAU93486.2 - 3.1e-05 23.6 0.0 0.083 12.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EAU93486.2 - 0.00028 21.2 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 EAU93486.2 - 0.0012 18.4 0.1 0.61 9.6 0.0 3.2 3 2 0 3 3 3 1 Elongation factor Tu GTP binding domain T2SSE PF00437.20 EAU93486.2 - 0.0019 17.3 0.0 0.1 11.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 EAU93486.2 - 0.0027 16.9 0.2 0.053 12.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 EAU93486.2 - 0.0045 17.4 1.0 0.12 12.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 EAU93486.2 - 0.0065 16.0 0.1 0.2 11.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 EAU93486.2 - 0.0075 16.8 0.3 0.17 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EAU93486.2 - 0.009 15.8 0.7 4.5 7.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EAU93486.2 - 0.01 15.1 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EAU93486.2 - 0.016 15.8 1.2 0.99 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EAU93486.2 - 0.022 14.7 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EAU93486.2 - 0.056 13.2 0.6 0.54 10.0 0.0 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EAU93486.2 - 0.094 12.4 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EAU93486.2 - 0.1 12.2 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 EAU93486.2 - 0.16 11.1 0.1 3.7 6.6 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain Adeno_IVa2 PF02456.15 EAU93486.2 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein IIGP PF05049.13 EAU93486.2 - 0.26 10.3 0.5 0.79 8.7 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 EAU93486.2 - 0.27 11.2 1.6 9.6 6.2 0.0 3.1 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EAU93486.2 - 0.96 9.8 2.6 25 5.2 0.2 2.8 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 EAU93486.2 - 4.1 7.8 4.9 0.86 10.0 0.3 2.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EAU93487.1 - 4.5e-11 42.8 0.0 7.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EAU93487.1 - 2.1e-09 37.0 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EAU93487.1 - 5.7e-07 29.7 0.1 0.0059 16.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EAU93487.1 - 1.9e-06 27.9 0.1 4.7e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase Septin PF00735.18 EAU93487.1 - 0.0001 21.7 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Septin IIGP PF05049.13 EAU93487.1 - 0.00023 20.4 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 EAU93487.1 - 0.00038 21.0 0.0 0.00082 19.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EAU93487.1 - 0.00099 19.4 0.0 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EAU93487.1 - 0.015 15.7 0.0 0.061 13.7 0.0 2.0 1 1 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 EAU93487.1 - 0.073 12.8 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EAU93487.1 - 0.086 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein VirE PF05272.11 EAU93487.1 - 0.17 11.6 0.0 1.5 8.5 0.0 2.0 1 1 1 2 2 2 0 Virulence-associated protein E cobW PF02492.19 EAU93487.1 - 0.19 11.3 0.1 0.45 10.1 0.0 1.7 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FUSC PF04632.12 EAU93487.1 - 0.29 9.6 0.9 0.41 9.1 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C2H2_jaz PF12171.8 EAU93488.2 - 3.7e-22 78.1 24.5 3.3e-05 24.0 0.1 6.7 5 1 1 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EAU93488.2 - 6.8e-22 77.1 33.1 0.00017 21.9 0.1 7.3 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EAU93488.2 - 1.5e-17 62.8 29.8 0.0057 17.4 0.1 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-C2H2 PF00096.26 EAU93488.2 - 1.9e-16 59.5 28.5 0.00065 20.0 0.1 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EAU93488.2 - 5.1e-08 32.7 32.6 0.0034 17.3 0.1 7.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU93488.2 - 0.00059 20.2 27.6 0.63 10.6 0.2 7.4 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_2 PF12756.7 EAU93488.2 - 0.0033 17.7 31.8 0.057 13.7 0.7 6.3 2 2 5 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EAU93488.2 - 2.7 8.5 15.9 0.3 11.6 0.8 4.1 5 0 0 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 EAU93488.2 - 3.3 7.7 16.0 4.9 7.2 0.0 5.7 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Peptidase_S10 PF00450.22 EAU93493.2 - 3e-05 23.6 0.0 4.1e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 EAU93494.2 - 4.6e-151 486.2 63.9 3.4e-11 43.5 0.3 20.7 20 0 0 20 20 20 20 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EAU93494.2 - 2.1e-59 197.8 0.0 0.0014 18.9 0.0 18.5 1 1 15 18 18 18 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EAU93494.2 - 5.3e-34 117.6 6.9 0.0046 16.0 0.0 13.8 3 2 11 15 15 15 9 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EAU93494.2 - 1.2e-11 44.3 3.1 31 4.7 0.0 9.6 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat NACHT PF05729.12 EAU93494.2 - 3.1e-08 33.7 0.1 5.5e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EAU93494.2 - 1.4e-05 25.6 0.0 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Proteasome_A_N PF10584.9 EAU93494.2 - 0.00061 19.4 14.9 65 3.3 0.0 11.7 14 0 0 14 14 14 0 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 EAU93494.2 - 0.0012 18.3 13.5 8.7 5.6 0.1 8.4 8 2 2 10 10 10 1 Neuroblastoma-amplified sequence, N terminal DUF4596 PF15363.6 EAU93494.2 - 0.0017 18.6 23.1 0.55 10.5 0.3 7.8 8 0 0 8 8 8 2 Domain of unknown function (DUF4596) Gmad1 PF10647.9 EAU93494.2 - 0.003 17.3 29.5 1.1 9.0 1.5 7.0 4 3 3 7 7 7 4 Lipoprotein LpqB beta-propeller domain ChapFlgA PF13144.6 EAU93494.2 - 0.013 15.6 0.0 1.1e+02 2.9 0.0 5.4 6 0 0 6 6 5 0 Chaperone for flagella basal body P-ring formation Nup160 PF11715.8 EAU93494.2 - 0.024 13.3 6.7 81 1.7 0.0 7.2 4 3 5 10 10 10 0 Nucleoporin Nup120/160 AAA_22 PF13401.6 EAU93494.2 - 0.04 14.2 0.0 0.16 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EAU93494.2 - 0.044 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EAU93494.2 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Peptidase_S9_N PF02897.15 EAU93494.2 - 0.14 10.9 0.0 45 2.7 0.0 4.6 6 1 2 8 8 8 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S10 PF00450.22 EAU93495.1 - 1.2e-101 341.2 0.0 1.4e-101 340.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pox_A9 PF04835.12 EAU93495.1 - 0.13 12.4 2.5 0.13 12.4 0.0 2.2 3 0 0 3 3 3 0 A9 protein conserved region Abhydrolase_1 PF00561.20 EAU93496.1 - 3e-44 151.6 0.0 3.8e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU93496.1 - 0.0082 16.8 3.6 0.016 15.8 3.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EAU93496.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein p450 PF00067.22 EAU93497.1 - 1e-79 268.5 0.0 1.2e-79 268.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.16 EAU93499.2 - 1.3e-126 422.3 11.1 1.6e-126 422.0 11.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase AAA_33 PF13671.6 EAU93500.2 - 0.021 15.0 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EAU93500.2 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 EAU93500.2 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EAU93500.2 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase DotA PF11388.8 EAU93500.2 - 0.15 12.3 0.0 0.9 9.8 0.1 2.3 2 1 0 2 2 2 0 Phagosome trafficking protein DotA Aminotran_4 PF01063.19 EAU93503.2 - 5e-28 98.5 0.0 8.9e-28 97.7 0.0 1.5 1 1 0 1 1 1 1 Amino-transferase class IV NUDIX PF00293.28 EAU93504.2 - 0.00021 21.3 0.0 0.00066 19.7 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain CSTF2_hinge PF14327.6 EAU93504.2 - 0.014 15.9 0.3 0.029 14.8 0.3 1.5 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 GRP PF07172.11 EAU93510.2 - 0.0012 19.5 3.6 0.0012 19.5 3.6 2.6 2 0 0 2 2 2 1 Glycine rich protein family TMEM154 PF15102.6 EAU93510.2 - 0.022 14.7 2.3 0.044 13.7 2.3 1.4 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 EAU93510.2 - 0.025 13.4 0.1 0.036 12.9 0.1 1.1 1 0 0 1 1 1 0 Amnionless DUF5305 PF17231.2 EAU93510.2 - 0.097 12.1 0.5 0.16 11.3 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SSP160 PF06933.11 EAU93510.2 - 0.14 10.3 7.8 0.21 9.7 7.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 EAU93510.2 - 1 9.8 7.1 0.094 13.2 2.1 1.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Tyrosinase PF00264.20 EAU93514.2 - 1.4e-39 136.7 0.0 1.9e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Fumarate_red_D PF02313.17 EAU93515.1 - 1.5e-05 25.1 0.0 1.2 9.3 0.0 3.3 3 0 0 3 3 3 3 Fumarate reductase subunit D PEP-CTERM PF07589.11 EAU93515.1 - 0.32 11.1 1.9 12 6.1 0.1 3.1 3 0 0 3 3 3 0 PEP-CTERM motif DUF4750 PF15938.5 EAU93516.1 - 0.12 12.1 0.6 0.23 11.1 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4750) Ribonuc_L-PSP PF01042.21 EAU93517.1 - 6.1e-20 71.4 0.0 7.7e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-MYND PF01753.18 EAU93520.2 - 2e-10 40.6 7.9 3.9e-10 39.6 7.9 1.5 1 0 0 1 1 1 1 MYND finger Spem1 PF15670.5 EAU93520.2 - 0.026 14.1 1.6 0.042 13.4 1.6 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 FERM_F2 PF18377.1 EAU93520.2 - 0.058 13.3 0.0 13 5.8 0.0 2.9 2 1 1 3 3 3 0 FERM F2 acyl-CoA binding protein-like domain zf-Mss51 PF13824.6 EAU93520.2 - 0.4 10.8 4.4 0.84 9.8 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4449 PF14613.6 EAU93522.1 - 4e-33 114.8 0.0 4e-33 114.8 0.0 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) SNN_cytoplasm PF09051.10 EAU93524.1 - 0.018 14.9 0.8 5.1 7.0 0.1 2.7 2 0 0 2 2 2 0 Stannin cytoplasmic Plavaka PF18759.1 EAU93525.2 - 8.7e-125 416.2 0.0 1.1e-124 415.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Snapin_Pallidin PF14712.6 EAU93525.2 - 0.54 10.7 3.0 1.2 9.6 3.0 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Gram_pos_anchor PF00746.21 EAU93527.1 - 2 8.5 5.2 9.9 6.2 0.7 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Tyrosinase PF00264.20 EAU93528.2 - 9.2e-40 137.3 0.0 1.3e-39 136.8 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase PP2C PF00481.21 EAU93530.2 - 4.5e-17 62.5 0.0 6.4e-11 42.4 0.0 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 EAU93530.2 - 0.071 13.0 0.0 7.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) CC2-LZ PF16516.5 EAU93531.1 - 5.7 7.4 5.8 3.1 8.2 3.2 1.9 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF5508 PF17621.2 EAU93532.1 - 0.074 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5508) iPGM_N PF06415.13 EAU93538.2 - 7.5e-76 254.3 0.0 1.1e-75 253.8 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EAU93538.2 - 1.5e-72 244.0 0.2 2.1e-72 243.4 0.2 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EAU93538.2 - 1.8e-06 27.8 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EAU93538.2 - 1e-05 25.1 0.0 3.6e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 EAU93538.2 - 0.0012 17.8 0.1 0.003 16.6 0.1 1.6 2 0 0 2 2 2 1 Alkaline phosphatase PglZ PF08665.12 EAU93538.2 - 0.003 17.7 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 PglZ domain Methyltransf_31 PF13847.6 EAU93538.2 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain KDZ PF18758.1 EAU93539.1 - 1.9e-46 158.4 0.2 3.9e-46 157.4 0.2 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Seryl_tRNA_N PF02403.22 EAU93540.2 - 0.032 14.5 5.2 1.1 9.5 0.4 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 EAU93540.2 - 0.041 14.1 4.3 0.61 10.4 0.3 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 EAU93540.2 - 0.19 11.5 5.5 0.073 12.8 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator Prominin PF05478.11 EAU93540.2 - 0.23 9.3 2.0 0.41 8.5 2.0 1.3 1 0 0 1 1 1 0 Prominin DUF948 PF06103.11 EAU93540.2 - 0.23 11.7 3.7 3.2 8.1 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 EAU93540.2 - 0.27 11.9 2.3 0.79 10.4 0.4 2.7 2 0 0 2 2 2 0 SlyX Cnn_1N PF07989.11 EAU93540.2 - 0.53 10.5 8.3 0.06 13.5 1.0 2.9 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 EAU93540.2 - 2.9 6.7 11.1 0.05 12.5 4.1 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein JmjN PF02375.17 EAU93541.2 - 0.12 12.3 0.3 0.33 11.0 0.3 1.8 1 0 0 1 1 1 0 jmjN domain KDZ PF18758.1 EAU93542.2 - 2.2e-45 155.0 1.3 4e-45 154.1 1.3 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EAU93542.2 - 1e-20 73.9 0.2 2.8e-20 72.5 0.2 1.8 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EAU93542.2 - 0.013 15.6 0.2 0.033 14.3 0.2 1.6 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases Spore_coat_CotO PF14153.6 EAU93543.2 - 3.8 7.4 8.2 2.9 7.8 5.9 1.8 2 0 0 2 2 2 0 Spore coat protein CotO F-box-like PF12937.7 EAU93548.2 - 0.00096 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like CRISPR_Cse2 PF09485.10 EAU93548.2 - 0.17 12.4 0.5 0.27 11.7 0.5 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Rotavirus_VP7 PF05868.11 EAU93549.1 - 0.062 12.7 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 V-ATPase_G PF03179.15 EAU93549.1 - 0.91 10.1 8.0 1.4 9.5 8.0 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF3987 PF13148.6 EAU93549.1 - 5 6.0 6.7 6.8 5.6 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATP_bind_2 PF03668.15 EAU93551.1 - 0.087 12.1 0.1 0.093 12.0 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family F-box-like PF12937.7 EAU93552.1 - 0.00019 21.2 0.3 0.00082 19.2 0.3 2.2 1 0 0 1 1 1 1 F-box-like LytB_WW PF18342.1 EAU93554.1 - 0.049 13.8 0.1 0.44 10.7 0.0 2.7 2 0 0 2 2 2 0 Endo-beta-N-acetylglucosaminidase LytB WW domain DUF3987 PF13148.6 EAU93555.1 - 5.3 6.0 5.7 7.9 5.4 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Pyrophosphatase PF00719.19 EAU93556.2 - 0.056 13.3 1.7 0.073 12.9 1.7 1.2 1 0 0 1 1 1 0 Inorganic pyrophosphatase DUF4882 PF16223.5 EAU93556.2 - 0.12 11.6 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4882) F-box PF00646.33 EAU93557.1 - 1.9e-05 24.4 0.0 4.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EAU93557.1 - 0.0003 20.6 0.0 0.00071 19.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Med12 PF09497.10 EAU93557.1 - 0.079 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 ERCC4 PF02732.15 EAU93561.2 - 2.5e-05 24.5 0.0 0.2 11.9 0.0 2.6 1 1 1 2 2 2 2 ERCC4 domain CCDC106 PF15794.5 EAU93561.2 - 0.038 13.7 4.9 0.066 12.9 4.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF2848 PF11010.8 EAU93563.1 - 0.086 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) F-box-like PF12937.7 EAU93564.1 - 2.7e-07 30.4 0.2 6.2e-07 29.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EAU93564.1 - 8.5e-06 25.5 1.5 5.4e-05 23.0 0.1 2.7 2 0 0 2 2 2 1 F-box domain DUF21 PF01595.20 EAU93571.2 - 3e-26 92.2 0.2 4.9e-26 91.5 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EAU93571.2 - 1.6e-05 25.2 0.0 0.14 12.7 0.0 3.2 3 0 0 3 3 3 2 CBS domain Xol-1_N PF09108.10 EAU93571.2 - 0.067 13.0 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal F-box-like PF12937.7 EAU93572.1 - 1.7e-08 34.2 0.7 4.5e-08 32.9 0.7 1.8 1 0 0 1 1 1 1 F-box-like TPR_10 PF13374.6 EAU93574.2 - 3.2e-33 112.7 4.7 0.00038 20.2 0.0 11.5 10 1 0 10 10 10 7 Tetratricopeptide repeat CHAT PF12770.7 EAU93574.2 - 9.4e-30 104.0 0.0 6.7e-29 101.2 0.0 2.1 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.6 EAU93574.2 - 2.2e-13 50.3 10.2 0.17 12.2 0.0 9.9 6 4 5 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAU93574.2 - 2.9e-05 23.8 4.3 0.75 10.0 0.0 8.1 10 0 0 10 10 10 1 Tetratricopeptide repeat Ribosomal_L22e PF01776.17 EAU93574.2 - 0.016 15.6 0.0 47 4.4 0.0 4.4 5 0 0 5 5 5 0 Ribosomal L22e protein family MIT PF04212.18 EAU93574.2 - 0.042 13.9 0.5 40 4.4 0.0 4.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EAU93574.2 - 0.16 12.3 6.8 8.9 6.8 0.0 6.6 9 0 0 9 9 9 0 Tetratricopeptide repeat AAA PF00004.29 EAU93575.1 - 6.2e-15 55.8 0.0 1.1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EAU93575.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EAU93575.1 - 0.011 16.1 0.6 0.068 13.5 0.6 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EAU93575.1 - 0.016 15.5 0.5 0.44 10.8 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 EAU93575.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RD3 PF14473.6 EAU93576.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 RD3 protein Pkinase PF00069.25 EAU93577.2 - 1.5e-54 185.1 0.0 3.9e-25 88.7 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 EAU93577.2 - 4.2e-48 164.1 0.0 4.2e-48 164.1 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 EAU93577.2 - 5.1e-24 85.0 0.1 1.6e-07 30.9 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EAU93577.2 - 1.4e-15 57.6 0.0 4.9e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 EAU93577.2 - 1.2e-06 28.1 0.0 2.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase CPSF100_C PF13299.6 EAU93577.2 - 0.0014 18.9 1.4 0.0031 17.7 1.4 1.5 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal FTA2 PF13095.6 EAU93577.2 - 0.26 10.9 1.2 10 5.7 0.0 3.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 ChaC PF04752.12 EAU93578.2 - 9.7e-38 130.0 0.0 2.9e-32 112.2 0.0 2.1 1 1 1 2 2 2 2 ChaC-like protein tRNA_U5-meth_tr PF05958.11 EAU93579.1 - 1.9e-18 66.6 0.0 2.8e-17 62.8 0.0 2.7 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EAU93579.1 - 1.5e-06 27.9 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 EAU93579.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EAU93579.1 - 0.0056 17.4 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EAU93579.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EAU93579.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 EAU93579.1 - 0.047 13.1 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DLH PF01738.18 EAU93580.2 - 3.2e-18 66.1 0.0 3.7e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EAU93580.2 - 0.00017 21.4 0.1 0.0031 17.2 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU93580.2 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EAU93581.2 - 2.2e-21 76.4 0.0 2.5e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EAU93581.2 - 5.6e-05 22.9 1.1 0.0002 21.1 1.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EAU93581.2 - 0.0033 16.9 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Pkinase PF00069.25 EAU93582.1 - 3.5e-60 203.6 0.0 5.9e-60 202.9 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EAU93582.1 - 1.4e-28 99.9 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EAU93582.1 - 3.7e-07 29.8 0.0 1.3e-06 27.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EAU93582.1 - 0.029 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EAU93582.1 - 0.044 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.22 EAU93583.2 - 2.9e-69 234.0 0.1 1.8e-68 231.4 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 4HBT PF03061.22 EAU93587.1 - 1.3e-10 41.4 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TPR_10 PF13374.6 EAU93588.2 - 4.5e-49 163.1 7.6 7.2e-05 22.5 0.1 15.1 15 0 0 15 15 15 13 Tetratricopeptide repeat CHAT PF12770.7 EAU93588.2 - 7.6e-29 101.0 0.0 1.3e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EAU93588.2 - 6e-08 32.9 19.1 1.9 8.8 0.2 11.1 8 3 6 14 14 14 4 Tetratricopeptide repeat TPR_7 PF13176.6 EAU93588.2 - 0.012 15.6 1.2 7.4 6.9 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF2730 PF10805.8 EAU93588.2 - 0.03 14.4 0.0 51 4.0 0.0 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF2730) DUF4404 PF14357.6 EAU93588.2 - 0.13 12.9 7.0 8.9 7.0 0.3 5.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4404) Methyltransf_16 PF10294.9 EAU93589.2 - 1.7e-13 50.7 0.0 2.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EAU93589.2 - 0.0029 18.3 0.0 0.0076 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EAU93589.2 - 0.018 15.8 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EAU93589.2 - 0.1 12.4 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TPR_1 PF00515.28 EAU93591.1 - 1.7e-10 40.3 0.5 0.013 15.3 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EAU93591.1 - 8.3e-10 38.0 0.1 0.078 13.1 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EAU93591.1 - 5.4e-09 35.6 3.4 0.0041 16.9 0.0 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU93591.1 - 3.6e-07 29.9 0.0 5 7.6 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EAU93591.1 - 1.7e-06 28.4 3.7 3.9 8.6 0.0 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EAU93591.1 - 6.9e-06 25.7 5.2 4.4 7.5 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EAU93591.1 - 5e-05 22.9 0.3 5.9 6.7 0.1 3.6 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 EAU93591.1 - 0.00071 20.0 0.7 6.7 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Vta1_C PF18097.1 EAU93591.1 - 0.00099 18.8 1.8 4.6 7.0 0.0 3.5 3 0 0 3 3 3 2 Vta1 C-terminal domain MIT PF04212.18 EAU93591.1 - 0.0012 18.8 0.1 0.6 10.2 0.1 3.0 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EAU93591.1 - 0.0013 19.3 0.3 15 6.3 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EAU93591.1 - 0.0014 18.9 4.4 5.7 7.3 0.1 4.5 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EAU93591.1 - 0.016 14.6 0.3 4.9 6.4 0.2 3.2 1 1 3 4 4 4 0 MalT-like TPR region TPR_15 PF13429.6 EAU93591.1 - 0.038 13.2 0.0 6.8 5.8 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Peptidase_M43 PF05572.13 EAU93594.2 - 5.5e-10 39.3 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EAU93594.2 - 0.06 13.5 0.1 0.14 12.3 0.1 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M43 PF05572.13 EAU93595.1 - 8.1e-13 48.6 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 EAU93595.1 - 7.7e-05 23.2 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EAU93595.1 - 9.9e-05 22.6 0.0 0.0002 21.6 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EAU93595.1 - 0.014 15.0 0.1 0.035 13.7 0.0 1.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Spherulin4 PF12138.8 EAU93595.1 - 0.018 14.7 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Spherulation-specific family 4 Peptidase_M10 PF00413.24 EAU93595.1 - 0.031 14.1 0.7 0.062 13.2 0.7 1.6 1 1 0 1 1 1 0 Matrixin Nop14 PF04147.12 EAU93596.1 - 0.62 8.2 39.0 0.78 7.9 39.0 1.3 1 0 0 1 1 1 0 Nop14-like family zf-LITAF-like PF10601.9 EAU93598.1 - 0.0002 21.5 0.2 0.00031 20.9 0.2 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zinc_ribbon_2 PF13240.6 EAU93598.1 - 0.12 12.1 0.7 0.2 11.4 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-LITAF-like PF10601.9 EAU93599.2 - 0.0027 17.9 0.1 0.0039 17.4 0.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain ELP6 PF09807.9 EAU93602.2 - 1.1e-05 25.0 0.0 4.3e-05 23.1 0.0 1.8 1 1 1 2 2 2 1 Elongation complex protein 6 Ribosomal_L7Ae PF01248.26 EAU93603.2 - 2.2e-21 75.4 0.9 4e-21 74.6 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metallophos PF00149.28 EAU93605.2 - 8.9e-13 49.2 1.1 1.5e-12 48.4 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.7 EAU93606.1 - 4.4e-12 45.7 1.1 1.1e-11 44.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EAU93606.1 - 0.28 11.1 2.0 1.3 8.9 0.0 3.2 3 1 0 3 3 3 0 F-box domain DUF4800 PF16057.5 EAU93607.1 - 0.22 10.8 0.0 0.29 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Alpha-amylase PF00128.24 EAU93608.2 - 2e-118 395.8 0.1 2.8e-118 395.4 0.1 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EAU93608.2 - 0.017 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 EAU93608.2 - 0.045 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain DSPc PF00782.20 EAU93609.1 - 3.1e-06 27.0 0.0 4.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EAU93609.1 - 0.00016 21.9 0.0 0.00059 20.0 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.12 EAU93609.1 - 0.0021 17.8 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EAU93609.1 - 0.0097 15.9 0.1 0.028 14.4 0.1 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EAU93609.1 - 0.039 13.5 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FlxA PF14282.6 EAU93609.1 - 0.072 13.1 0.2 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 FlxA-like protein Cullin PF00888.22 EAU93610.2 - 6.6e-18 64.7 0.0 1e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EAU93610.2 - 1.3e-15 57.6 0.4 1.5e-14 54.3 0.1 2.9 4 0 0 4 4 4 1 Anaphase promoting complex (APC) subunit 2 GST_N_2 PF13409.6 EAU93612.1 - 6.8e-11 42.3 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EAU93612.1 - 4.1e-10 39.9 0.0 1e-09 38.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EAU93612.1 - 9.9e-06 25.7 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EAU93612.1 - 0.0003 20.8 0.1 0.001 19.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EAU93612.1 - 0.0051 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EAU93612.1 - 0.0054 17.3 0.0 0.012 16.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EAU93612.1 - 0.063 13.6 0.0 0.43 10.9 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain peroxidase PF00141.23 EAU93612.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Peroxidase p450 PF00067.22 EAU93613.1 - 1.7e-76 257.9 0.0 1.9e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EAU93614.2 - 1.4e-09 37.6 0.5 9.1e-09 35.1 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EAU93614.2 - 0.023 14.6 0.4 0.11 12.4 0.2 2.3 2 0 0 2 2 2 0 F-box domain Metallophos PF00149.28 EAU93615.2 - 9.9e-12 45.8 1.0 1.9e-11 44.9 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_C14 PF00656.22 EAU93616.2 - 1.5e-45 156.1 0.0 5.3e-45 154.3 0.0 1.8 1 1 0 1 1 1 1 Caspase domain DUF3560 PF12083.8 EAU93616.2 - 0.04 14.0 0.8 0.088 12.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) Peptidase_C13 PF01650.18 EAU93616.2 - 0.091 12.3 0.1 2.6 7.5 0.0 2.2 1 1 1 2 2 2 0 Peptidase C13 family TFIIA PF03153.13 EAU93616.2 - 9.3 6.1 10.0 13 5.7 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase_Tyr PF07714.17 EAU93617.2 - 2e-24 86.3 0.0 2.5e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EAU93617.2 - 6.6e-19 68.3 0.0 9.8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain AAA_33 PF13671.6 EAU93618.1 - 0.0001 22.5 0.2 0.0011 19.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EAU93618.1 - 0.00078 19.2 0.0 0.0012 18.6 0.0 1.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EAU93618.1 - 0.0013 19.3 0.1 0.01 16.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 EAU93618.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 EAU93618.1 - 0.023 14.1 0.0 0.05 13.0 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EAU93618.1 - 0.12 12.8 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2 PF00096.26 EAU93620.2 - 1e-09 38.3 7.8 0.00062 20.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EAU93620.2 - 2.9e-07 30.8 8.7 0.0065 17.2 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EAU93620.2 - 8.5e-07 29.1 7.8 2.5e-05 24.5 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EAU93620.2 - 0.00098 19.4 0.4 0.32 11.3 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EAU93620.2 - 0.0014 18.3 1.7 0.15 11.9 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-met PF12874.7 EAU93620.2 - 0.0021 18.4 1.3 0.39 11.2 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EAU93620.2 - 0.0065 16.4 2.5 2.8 8.0 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EAU93620.2 - 0.0077 16.1 1.6 0.0077 16.1 1.6 2.8 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 EAU93620.2 - 0.058 14.1 2.3 1.5 9.5 2.3 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Sec23_Sec24 PF04810.15 EAU93620.2 - 0.11 12.6 0.3 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-MYST PF17772.1 EAU93620.2 - 0.2 11.3 1.7 1.1 8.9 0.1 2.2 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 EAU93620.2 - 0.21 11.4 3.4 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EAU93620.2 - 0.34 11.0 7.4 2.5 8.2 1.6 2.6 1 1 1 2 2 2 0 BED zinc finger ARS2 PF04959.13 EAU93620.2 - 0.46 10.8 3.8 1.6 9.1 0.5 2.3 2 1 0 2 2 2 0 Arsenite-resistance protein 2 zf-C2H2_2 PF12756.7 EAU93620.2 - 0.56 10.6 3.2 3.3 8.1 0.9 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF4712 PF15830.5 EAU93620.2 - 1.1 8.9 4.7 1.5 8.4 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) SR-25 PF10500.9 EAU93620.2 - 4.7 6.8 14.2 8.8 5.9 14.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FYVE PF01363.21 EAU93620.2 - 8.6 6.6 8.6 1e+02 3.2 8.6 2.1 1 1 0 1 1 1 0 FYVE zinc finger Bromodomain PF00439.25 EAU93621.2 - 5.2e-22 77.7 0.6 1.7e-16 60.1 0.1 3.2 3 0 0 3 3 3 2 Bromodomain BAH PF01426.18 EAU93621.2 - 9.8e-11 41.6 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain 5TM-5TMR_LYT PF07694.12 EAU93622.2 - 0.028 13.9 0.7 0.05 13.1 0.7 1.3 1 0 0 1 1 1 0 5TMR of 5TMR-LYT A_deaminase PF00962.22 EAU93623.1 - 7.4e-18 65.0 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase PDE8 PF08629.10 EAU93624.1 - 0.067 13.2 1.0 0.24 11.4 1.0 1.9 1 0 0 1 1 1 0 PDE8 phosphodiesterase MGC-24 PF05283.11 EAU93624.1 - 0.094 13.2 0.0 0.094 13.2 0.0 3.4 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Beta_helix PF13229.6 EAU93625.1 - 8.9e-08 32.1 18.8 1.6e-06 28.1 16.1 3.0 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EAU93625.1 - 0.00013 21.3 3.1 0.035 13.4 0.2 2.2 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) SKG6 PF08693.10 EAU93625.1 - 0.0012 18.2 1.7 0.0032 16.8 1.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Disaggr_assoc PF08480.10 EAU93625.1 - 0.011 15.6 6.3 0.064 13.1 3.0 2.8 2 1 0 2 2 2 0 Disaggregatase related Phage_holin_2_1 PF04971.12 EAU93625.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S Adeno_E3_CR2 PF02439.15 EAU93625.1 - 0.2 11.4 1.5 0.36 10.6 1.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Arm PF00514.23 EAU93626.2 - 4.6e-05 23.3 17.4 0.11 12.6 0.3 8.1 9 1 0 9 9 9 2 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 EAU93626.2 - 0.013 15.9 0.0 9.9 6.6 0.0 3.1 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF3636 PF12331.8 EAU93626.2 - 0.024 14.5 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) DRIM PF07539.12 EAU93626.2 - 0.081 11.2 1.0 1.5 7.0 0.1 2.5 3 0 0 3 3 3 0 Down-regulated in metastasis HEAT_2 PF13646.6 EAU93626.2 - 0.081 13.3 10.6 2.8 8.4 0.5 5.5 4 1 0 4 4 4 0 HEAT repeats Adaptin_N PF01602.20 EAU93626.2 - 0.27 9.7 0.7 28 3.1 0.0 3.5 4 0 0 4 4 4 0 Adaptin N terminal region HEAT PF02985.22 EAU93626.2 - 7 7.2 27.3 0.67 10.4 0.1 8.1 10 0 0 10 10 10 0 HEAT repeat DUF2189 PF09955.9 EAU93628.2 - 0.63 10.3 7.6 0.46 10.8 0.5 2.7 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) Cellulase PF00150.18 EAU93630.1 - 1.4e-14 54.2 0.0 2.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 EAU93630.1 - 3.4e-06 26.9 0.0 0.02 14.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 EAU93630.1 - 0.0031 16.9 0.0 0.014 14.7 0.0 2.0 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 EAU93630.1 - 0.14 11.3 0.0 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Aminotran_1_2 PF00155.21 EAU93634.2 - 8.3e-16 58.1 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EAU93634.2 - 0.097 11.3 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DUF4158 PF13700.6 EAU93634.2 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Hva1_TUDOR PF11160.8 EAU93635.2 - 1.9 8.7 6.0 9.1 6.5 0.1 3.7 3 0 0 3 3 3 0 Hypervirulence associated proteins TUDOR domain Aminotran_1_2 PF00155.21 EAU93638.1 - 0.056 12.6 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Abhydrolase_1 PF00561.20 EAU93639.1 - 1.5e-16 60.8 0.3 1.2e-12 48.1 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EAU93639.1 - 4.4e-13 50.4 0.0 6.9e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EAU93639.1 - 0.00038 19.8 0.0 0.0052 16.1 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 AMP-binding PF00501.28 EAU93640.1 - 5.4e-31 107.6 0.0 1.2e-29 103.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme PS_Dcarbxylase PF02666.15 EAU93641.1 - 3.9e-70 235.5 0.0 1.2e-67 227.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase WD40 PF00400.32 EAU93642.2 - 0.005 17.7 13.7 0.49 11.4 0.3 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF5127 PF17168.4 EAU93643.2 - 5.8e-55 186.5 0.1 9.1e-55 185.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EAU93643.2 - 1.1e-47 161.9 0.2 1.9e-47 161.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EAU93643.2 - 6.5e-12 46.2 1.7 3.1e-11 44.0 0.1 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF1793) GD_AH_C PF04295.13 EAU93643.2 - 0.079 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus SKG6 PF08693.10 EAU93643.2 - 0.12 11.8 0.8 0.21 11.0 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TolA_bind_tri PF16331.5 EAU93643.2 - 0.27 11.4 5.3 0.5 10.5 5.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation AMP-binding PF00501.28 EAU93644.2 - 0.0016 17.2 0.0 0.0016 17.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme G-alpha PF00503.20 EAU93646.2 - 3.3e-99 332.4 0.1 4.1e-99 332.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EAU93646.2 - 9.6e-12 44.7 3.2 2.5e-07 30.3 0.5 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EAU93646.2 - 0.0093 15.3 4.2 0.27 10.6 0.1 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EAU93646.2 - 0.019 15.0 0.5 2.7 8.1 0.0 2.7 3 0 0 3 3 2 0 50S ribosome-binding GTPase Roc PF08477.13 EAU93646.2 - 0.02 15.1 0.3 1.9 8.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EAU93646.2 - 0.035 13.8 0.0 0.047 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Tenui_N PF05733.11 EAU93646.2 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein AAA_29 PF13555.6 EAU93646.2 - 0.077 12.8 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EAU93646.2 - 0.078 12.7 0.4 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain MCM PF00493.23 EAU93646.2 - 0.11 11.5 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain RsgA_GTPase PF03193.16 EAU93646.2 - 0.12 12.3 0.1 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EAU93646.2 - 0.15 11.4 0.1 0.44 9.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family TMA7 PF09072.10 EAU93646.2 - 0.16 12.9 2.7 0.38 11.6 2.7 1.6 1 0 0 1 1 1 0 Translation machinery associated TMA7 Dimer_Tnp_hAT PF05699.14 EAU93647.2 - 6.6e-12 45.0 0.0 1.6e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region tRNA-synt_1c PF00749.21 EAU93648.2 - 6.1e-69 232.3 0.0 8.7e-69 231.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-UBR PF02207.20 EAU93649.2 - 2.8e-18 65.8 16.3 2.8e-18 65.8 16.3 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EAU93649.2 - 0.016 15.0 0.1 0.046 13.5 0.1 1.8 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Alpha-amylase PF00128.24 EAU93650.1 - 1.1e-98 330.9 1.8 2.7e-96 323.1 1.8 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EAU93650.1 - 0.0065 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EAU93650.1 - 0.028 13.5 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 EAU93650.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) p450 PF00067.22 EAU93651.2 - 1.2e-65 222.1 0.0 7.2e-50 170.1 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 SNF2_N PF00176.23 EAU93652.2 - 8e-18 64.3 0.1 1.2e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU93652.2 - 6e-16 58.8 0.0 1.2e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU93652.2 - 4.1e-07 30.2 0.0 1.1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAU93652.2 - 0.0034 16.6 0.0 0.0067 15.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 EAU93653.2 - 5.2e-25 87.9 0.1 8.6e-25 87.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EAU93653.2 - 1.1e-14 54.6 0.0 2.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EAU93653.2 - 9.9e-06 25.7 0.3 2.1e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EAU93653.2 - 0.0037 16.5 0.0 0.0094 15.2 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_11 PF13086.6 EAU93653.2 - 0.025 14.4 0.1 1.6 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 EAU93653.2 - 0.18 11.3 0.3 0.4 10.1 0.3 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Abhydrolase_3 PF07859.13 EAU93656.1 - 5.3e-16 59.1 0.0 7.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EAU93656.1 - 2.1e-10 40.1 0.0 7.3e-10 38.2 0.0 1.9 2 1 0 2 2 2 1 Steryl acetyl hydrolase CHD5 PF04420.14 EAU93656.1 - 0.026 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 CHD5-like protein COesterase PF00135.28 EAU93656.1 - 0.11 11.3 0.0 1.2 7.9 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Cullin PF00888.22 EAU93657.2 - 1.4e-147 493.0 5.2 1.9e-147 492.6 5.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EAU93657.2 - 1.4e-21 76.3 2.1 2.3e-21 75.6 0.7 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF515 PF04415.12 EAU93657.2 - 0.02 13.3 0.5 0.034 12.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TPR_10 PF13374.6 EAU93658.2 - 2e-43 145.1 14.5 1e-06 28.4 0.0 12.8 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_12 PF13424.6 EAU93658.2 - 6.9e-08 32.7 24.4 0.28 11.5 0.2 10.6 10 4 4 14 14 14 3 Tetratricopeptide repeat TPR_17 PF13431.6 EAU93658.2 - 1.6e-06 28.1 3.2 1.9 9.0 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EAU93658.2 - 2.2e-05 24.3 0.1 42 4.7 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 EAU93658.2 - 0.0013 18.7 6.1 1.1e+02 3.3 0.0 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat Syntaxin-6_N PF09177.11 EAU93658.2 - 0.0015 19.1 0.1 14 6.3 0.0 4.9 4 1 0 4 4 4 1 Syntaxin 6, N-terminal TSC22 PF01166.18 EAU93658.2 - 0.043 14.1 0.0 0.24 11.7 0.0 2.3 1 0 0 1 1 1 0 TSC-22/dip/bun family TPR_7 PF13176.6 EAU93658.2 - 0.23 11.6 11.6 53 4.2 0.0 7.8 9 1 0 9 9 9 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EAU93658.2 - 3.6 7.7 7.5 77 3.5 0.0 5.2 6 0 0 6 6 6 0 Exonuclease VII small subunit APG6_N PF17675.1 EAU93665.1 - 0.21 12.1 2.0 0.75 10.3 0.1 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region AT_hook PF02178.19 EAU93667.2 - 0.0019 17.8 0.7 0.006 16.3 0.7 1.9 1 0 0 1 1 1 1 AT hook motif SR-25 PF10500.9 EAU93671.2 - 0.034 13.8 1.0 0.091 12.4 1.0 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KDZ PF18758.1 EAU93676.2 - 1.6e-48 165.2 0.2 6.7e-48 163.2 0.0 2.0 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EAU93676.2 - 3e-07 30.5 0.2 7.6e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EAU93676.2 - 0.0023 18.1 0.2 0.0047 17.1 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases HA PF03457.14 EAU93676.2 - 0.038 14.3 0.5 0.17 12.2 0.5 2.2 1 0 0 1 1 1 0 Helicase associated domain DctP PF03480.13 EAU93676.2 - 0.072 12.4 2.2 0.14 11.5 2.2 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DivIC PF04977.15 EAU93676.2 - 0.24 11.2 3.2 0.17 11.7 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 EAU93679.2 - 0.075 12.9 2.4 0.087 12.7 0.9 2.0 2 0 0 2 2 2 0 F-box-like BTB PF00651.31 EAU93681.1 - 0.011 16.0 0.0 0.033 14.4 0.0 1.8 1 1 0 1 1 1 0 BTB/POZ domain zf-MYND PF01753.18 EAU93684.2 - 7.3e-08 32.4 8.9 7.3e-08 32.4 8.9 2.0 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EAU93684.2 - 7.6 6.5 10.2 1.8 8.5 6.4 2.0 2 0 0 2 2 2 0 HIT zinc finger PRY PF13765.6 EAU93686.2 - 0.073 12.7 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 SPRY-associated domain MFS_1 PF07690.16 EAU93687.1 - 1e-17 64.1 45.3 1.2e-11 44.2 27.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EAU93687.1 - 4.7e-05 22.4 15.7 4.7e-05 22.4 15.7 2.8 3 1 1 4 4 4 2 Sugar (and other) transporter KDZ PF18758.1 EAU93688.2 - 4.3e-48 163.9 0.2 1.9e-47 161.7 0.0 2.1 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EAU93688.2 - 7.4e-10 38.9 0.2 6.4e-09 35.9 0.5 2.2 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases Peptidase_C48 PF02902.19 EAU93688.2 - 1.4e-05 25.1 0.0 2.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC2 PF18803.1 EAU93688.2 - 0.0012 19.0 2.0 0.0015 18.6 0.7 1.8 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases HA PF03457.14 EAU93688.2 - 0.072 13.4 0.5 0.34 11.3 0.5 2.2 1 0 0 1 1 1 0 Helicase associated domain DctP PF03480.13 EAU93688.2 - 0.14 11.5 2.1 0.25 10.6 2.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DivIC PF04977.15 EAU93688.2 - 0.3 10.9 2.3 0.36 10.6 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator HrpB7 PF09486.10 EAU93688.2 - 7.6 6.9 14.9 2.3 8.6 1.8 3.2 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) ADIP PF11559.8 EAU93689.2 - 0.1 12.7 0.2 0.14 12.2 0.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5310 PF17237.2 EAU93690.2 - 0.15 11.9 1.2 0.32 10.9 1.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5310) NADHdh PF00146.21 EFI26508.1 - 2.1e-112 375.3 23.4 2.4e-112 375.1 23.4 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Proton_antipo_M PF00361.20 EFI26509.1 - 6.5e-63 212.7 22.3 6.5e-63 212.7 22.3 2.3 3 0 0 3 3 3 1 Proton-conducting membrane transporter NADH5_C PF06455.11 EFI26509.1 - 7.5e-14 51.7 30.6 4.2e-08 33.0 8.6 5.1 3 2 1 4 4 4 2 NADH dehydrogenase subunit 5 C-terminus Proton_antipo_C PF01010.19 EFI26509.1 - 3.8e-05 23.4 12.5 7.8e-05 22.4 12.5 1.4 1 0 0 1 1 1 1 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Oxidored_q2 PF00420.24 EFI26510.1 - 2.1e-17 62.7 10.9 2.5e-17 62.4 10.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L XK-related PF09815.9 EFI26510.1 - 0.029 13.4 3.6 0.033 13.3 3.6 1.1 1 0 0 1 1 1 0 XK-related protein DUF5325 PF17259.2 EFI26510.1 - 3 7.8 15.2 17 5.3 7.4 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5325) Ac76 PF05814.11 EFI26510.1 - 3.4 7.7 9.4 4.9 7.2 9.4 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) DUF3098 PF11297.8 EFI26510.1 - 6.9 6.4 12.4 1.5 8.5 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3098) ATP-synt_C PF00137.21 EFI26511.1 - 2.6e-14 53.3 13.9 3.2e-14 53.0 13.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit C Oxidored_q3 PF00499.20 EFI26512.1 - 1.8e-36 125.0 20.8 2.4e-36 124.6 20.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 NTPase_P4 PF11602.8 EFI26512.1 - 0.12 11.6 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 ATP-synt_A PF00119.20 EFI26513.1 - 4.2e-44 151.0 27.9 5.5e-44 150.6 27.9 1.1 1 0 0 1 1 1 1 ATP synthase A chain Cytochrome_B PF00033.19 EFI26514.1 - 5.5e-71 238.3 22.6 2.3e-70 236.3 17.9 2.8 2 1 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_C PF00032.17 EFI26514.1 - 1.7e-37 127.8 2.3 1.7e-37 127.8 2.3 3.2 4 1 0 4 4 4 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N_2 PF13631.6 EFI26514.1 - 2.3e-31 109.1 16.0 2.3e-31 109.1 16.0 3.6 3 2 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.20 EFI26514.1 - 8.3e-05 22.3 29.4 0.0024 17.5 3.3 3.3 2 1 1 3 3 3 3 Prokaryotic cytochrome b561 DUF4405 PF14358.6 EFI26514.1 - 0.023 15.2 2.7 0.023 15.2 2.7 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) COX3 PF00510.18 EFI26515.1 - 1.7e-112 375.5 26.2 2.1e-112 375.2 26.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Proton_antipo_M PF00361.20 EFI26516.1 - 1.8e-72 244.0 25.9 1.8e-72 244.0 25.9 1.8 2 0 0 2 2 2 1 Proton-conducting membrane transporter COX1 PF00115.20 EFI26517.1 - 6.9e-150 499.7 53.7 8.5e-150 499.4 53.7 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DNA_pol_B_2 PF03175.13 EFI26518.1 - 1.1e-73 248.8 33.9 2.1e-61 208.2 16.3 3.9 2 1 1 3 3 3 2 DNA polymerase type B, organellar and viral Oxidored_q4 PF00507.19 EFI26519.1 - 5.9e-25 87.3 2.9 5.9e-25 87.3 2.9 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Proton_antipo_M PF00361.20 EFI26520.1 - 2.6e-62 210.7 30.4 2.5e-35 122.1 12.6 2.9 2 1 1 3 3 3 2 Proton-conducting membrane transporter SKG6 PF08693.10 EFI26521.1 - 1.3 8.5 8.4 3.4 7.1 8.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Fun_ATP-synt_8 PF05933.13 EFI26522.1 - 7.8e-16 58.0 13.5 8.8e-16 57.8 13.5 1.0 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) YMF19 PF02326.15 EFI26522.1 - 2.5 8.9 11.1 2.7 8.8 11.1 1.1 1 0 0 1 1 1 0 Plant ATP synthase F0 COX2 PF00116.20 EFI26523.1 - 4e-60 201.0 0.0 6.7e-60 200.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 EFI26523.1 - 2.1e-29 101.5 1.0 3.5e-29 100.8 1.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain BBE PF08031.12 EFI26524.1 - 1.2e-11 44.5 0.1 2.6e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EFI26524.1 - 7.3e-09 35.5 0.3 1.4e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Retrotrans_gag PF03732.17 EFI26526.1 - 0.0038 17.5 0.2 0.0038 17.5 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein GST_N PF02798.20 EFI26528.1 - 5.1e-14 52.4 0.0 9.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EFI26528.1 - 2.1e-12 47.2 0.0 3.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EFI26528.1 - 2.4e-10 40.6 0.0 4.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EFI26528.1 - 0.0095 15.9 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EFI26528.1 - 0.025 14.7 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_MA_2 PF13485.6 EFI26528.1 - 0.036 13.7 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase MA superfamily GST_N PF02798.20 EFI26529.1 - 5.4e-16 58.7 0.0 1.1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EFI26529.1 - 7.6e-13 48.7 0.0 1.7e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EFI26529.1 - 1.5e-08 34.8 0.0 4.5e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EFI26529.1 - 0.011 16.5 0.0 0.31 11.8 0.0 2.6 2 1 1 3 3 3 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 EFI26529.1 - 0.096 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_MA_2 PF13485.6 EFI26529.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase MA superfamily Helitron_like_N PF14214.6 EFI26531.1 - 4.4e-55 186.9 0.0 5.6e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Rep_1 PF01446.17 EFI26531.1 - 0.018 14.6 0.1 0.041 13.3 0.1 1.5 1 1 0 1 1 1 0 Replication protein Inovirus_Gp2 PF11726.8 EFI26531.1 - 0.027 14.4 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Inovirus Gp2 Phage_GPA PF05840.13 EFI26531.1 - 0.16 11.0 0.6 0.4 9.7 0.6 1.8 1 1 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Vac_Fusion PF02346.16 EFI26534.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 COG5 PF10392.9 EFI26534.1 - 0.067 13.4 0.1 0.088 13.0 0.1 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3931 PF13082.6 EFI26536.1 - 0.067 13.4 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) Ion_trans PF00520.31 EFI26538.1 - 0.044 13.0 2.5 1.2 8.3 0.3 2.2 1 1 1 2 2 2 0 Ion transport protein ZnuA PF01297.17 EFI26539.1 - 0.035 13.5 0.8 0.052 12.9 0.8 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Glyco_hydro_65m PF03632.15 EFI26539.1 - 0.14 10.9 0.4 0.21 10.4 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain F-box-like PF12937.7 EFI26541.1 - 5.9e-07 29.3 0.1 2.1e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 F-box-like DUF1996 PF09362.10 EFI26543.1 - 2.5e-05 24.4 0.2 2.9e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 EFI26544.1 - 2.1e-66 224.3 0.1 2.9e-66 223.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 EFI26545.1 - 0.002 18.2 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fasciclin PF02469.22 EFI26546.1 - 2e-28 99.2 0.0 9.8e-20 71.1 0.2 2.6 2 0 0 2 2 2 2 Fasciclin domain HEAT_2 PF13646.6 EFI26546.1 - 1.7e-08 34.8 2.1 3.9e-05 24.0 0.1 7.9 8 2 3 11 11 11 3 HEAT repeats Cnd1 PF12717.7 EFI26546.1 - 1.3e-05 25.2 10.5 0.03 14.4 0.2 5.8 6 1 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EFI26546.1 - 0.00012 22.0 9.7 7.4 7.1 0.0 8.2 9 0 0 9 9 9 1 HEAT repeat Arm PF00514.23 EFI26546.1 - 0.28 11.3 5.4 84 3.4 0.0 5.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EFI26546.1 - 1 7.8 5.7 16 3.9 0.6 3.3 2 1 0 2 2 2 0 Adaptin N terminal region HEAT_PBS PF03130.16 EFI26546.1 - 3.1 8.8 6.0 12 6.9 0.1 4.7 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EFI26546.1 - 3.4 8.3 8.5 3.4 8.3 0.1 5.7 7 1 1 8 8 8 0 HEAT-like repeat DctQ PF04290.12 EFI26547.1 - 0.027 14.4 1.0 0.54 10.2 0.1 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component ISK_Channel PF02060.15 EFI26547.1 - 0.24 11.1 0.1 0.4 10.4 0.1 1.3 1 0 0 1 1 1 0 Slow voltage-gated potassium channel DUF1418 PF07214.12 EFI26549.1 - 0.1 12.5 1.1 0.39 10.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Mobilization_B PF17511.2 EFI26550.1 - 0.23 11.8 0.9 0.69 10.3 0.9 1.8 1 0 0 1 1 1 0 Mobilization protein B Glycoprotein_B PF00606.18 EFI26550.1 - 0.25 10.7 0.0 0.39 10.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain KDZ PF18758.1 EFI26552.1 - 6.7e-42 143.6 0.2 4.8e-41 140.8 0.0 2.1 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI26552.1 - 7.3e-25 87.2 0.1 9.1e-22 77.3 0.0 2.6 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases MIF4G_like_2 PF09090.11 EFI26552.1 - 0.0095 15.4 0.7 0.019 14.5 0.7 1.4 1 0 0 1 1 1 1 MIF4G like zf_C2H2_13 PF18508.1 EFI26559.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger domain DUF3439 PF11921.8 EFI26560.1 - 0.016 15.2 15.5 0.41 10.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Med3 PF11593.8 EFI26562.1 - 0.077 12.2 2.7 0.079 12.1 2.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3530 PF12048.8 EFI26562.1 - 0.54 9.6 4.2 0.69 9.3 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BRF1 PF07741.13 EFI26565.1 - 0.023 15.1 5.2 0.023 15.1 5.2 3.2 4 0 0 4 4 4 0 Brf1-like TBP-binding domain PcfJ PF14284.6 EFI26565.1 - 2.3 8.1 9.1 0.38 10.6 2.8 2.3 2 0 0 2 2 2 0 PcfJ-like protein PepSY_2 PF13670.6 EFI26566.1 - 1.5 8.9 5.1 3.1 7.8 4.7 1.8 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain FTSW_RODA_SPOVE PF01098.19 EFI26566.1 - 3.5 6.5 5.6 4.3 6.2 5.6 1.1 1 0 0 1 1 1 0 Cell cycle protein Robl_LC7 PF03259.17 EFI26568.1 - 1.5e-06 27.8 0.1 0.00047 19.9 0.0 2.4 2 1 0 2 2 2 2 Roadblock/LC7 domain Questin_oxidase PF14027.6 EFI26569.1 - 1e-90 304.8 0.0 1.4e-90 304.3 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like FHA PF00498.26 EFI26570.1 - 2.3e-11 43.9 0.1 7.2e-11 42.3 0.1 1.9 1 0 0 1 1 1 1 FHA domain NACHT PF05729.12 EFI26570.1 - 1e-09 38.5 0.0 2.6e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EFI26570.1 - 0.00021 21.7 0.0 0.00021 21.7 0.0 2.9 2 1 0 2 2 1 1 AAA ATPase domain Taxilin PF09728.9 EFI26570.1 - 0.00051 19.3 6.1 0.0009 18.5 6.1 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein SF-assemblin PF06705.11 EFI26570.1 - 0.0073 15.7 8.4 0.012 14.9 8.4 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin DUF2408 PF10303.9 EFI26570.1 - 0.013 16.1 7.3 0.59 10.7 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.12 EFI26570.1 - 0.076 13.1 7.4 0.21 11.7 2.5 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.6 EFI26570.1 - 0.46 10.5 4.2 1.2 9.2 2.4 2.4 1 1 1 2 2 2 0 FlxA-like protein IFT46_B_C PF12317.8 EFI26570.1 - 0.73 9.5 2.9 17 5.1 0.4 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal ZapB PF06005.12 EFI26570.1 - 0.8 10.2 5.2 19 5.8 1.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EFI26570.1 - 0.97 9.3 4.9 0.6 10.0 0.7 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain CENP-H PF05837.12 EFI26570.1 - 1 9.8 4.6 1.1 9.7 1.7 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 EFI26570.1 - 1.4 7.7 11.6 1.1 8.0 9.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 EFI26570.1 - 2.2 8.6 8.3 2.1 8.6 0.3 3.4 1 1 1 3 3 3 0 Haemolysin XhlA FUSC PF04632.12 EFI26570.1 - 2.5 6.6 13.0 4.9 5.6 13.0 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 EFI26570.1 - 2.7 8.5 9.7 84 3.7 0.4 3.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 EFI26570.1 - 8 6.9 8.1 3 8.3 1.1 2.7 1 1 1 2 2 2 0 Syntaxin-like protein SKA2 PF16740.5 EFI26570.1 - 8.6 6.2 7.4 38 4.1 0.9 3.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 SAC3_GANP PF03399.16 EFI26573.1 - 2.5e-64 217.5 0.1 3.8e-64 216.9 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family MFS_1 PF07690.16 EFI26574.1 - 9.5e-41 139.9 44.9 1.4e-38 132.8 48.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EFI26574.1 - 2.8e-05 22.7 16.4 0.00061 18.3 16.4 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rad60-SLD PF11976.8 EFI26577.1 - 3.1e-10 39.7 0.0 4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EFI26577.1 - 6.5e-06 25.8 0.0 8.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 EFI26577.1 - 0.065 13.5 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain PB1 PF00564.24 EFI26577.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 PB1 domain Abhydrolase_3 PF07859.13 EFI26578.1 - 1e-16 61.5 0.0 2.1e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EFI26578.1 - 8.4e-08 31.5 0.0 7.3e-07 28.4 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EFI26578.1 - 0.00038 21.1 0.3 0.00058 20.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EFI26578.1 - 0.0027 16.7 0.0 0.0044 16.0 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EFI26578.1 - 0.019 14.2 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 EFI26578.1 - 0.019 14.0 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Say1_Mug180 PF10340.9 EFI26578.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.3 1 1 0 1 1 1 0 Steryl acetyl hydrolase Zip PF02535.22 EFI26579.1 - 7.3e-41 140.5 27.7 1.1e-31 110.3 1.3 3.7 2 2 0 2 2 2 2 ZIP Zinc transporter CbtA PF09490.10 EFI26579.1 - 0.42 10.3 13.5 0.38 10.5 0.1 3.0 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) DUF5134 PF17197.4 EFI26579.1 - 0.6 10.0 9.1 0.086 12.7 3.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5134) SelP_N PF04592.14 EFI26579.1 - 2.7 7.4 32.4 1.8 7.9 4.2 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region NicO PF03824.16 EFI26579.1 - 7.9 5.7 13.1 0.089 12.1 3.1 2.7 3 0 0 3 3 3 0 High-affinity nickel-transport protein NACHT PF05729.12 EFI26580.1 - 0.00043 20.2 0.6 0.5 10.3 0.0 2.1 1 1 1 2 2 2 2 NACHT domain AAA_24 PF13479.6 EFI26580.1 - 0.00057 19.7 0.2 0.003 17.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EFI26580.1 - 0.012 16.0 0.0 0.02 15.3 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EFI26580.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EFI26580.1 - 0.047 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 EFI26580.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EFI26580.1 - 0.11 12.1 0.1 4.7 6.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EFI26580.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 EFI26581.1 - 1.5e-10 40.9 13.3 1.4e-05 25.2 0.3 4.2 4 1 0 4 4 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EFI26581.1 - 2.6e-08 33.9 3.7 1.2e-06 28.7 0.2 3.6 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 EFI26581.1 - 9.4e-06 26.2 20.0 0.00069 20.2 2.1 4.3 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EFI26581.1 - 0.0004 20.3 0.7 0.0063 16.5 0.1 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EFI26581.1 - 0.00045 20.8 2.0 0.0053 17.5 0.3 3.9 4 0 0 4 4 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 EFI26581.1 - 0.022 15.0 2.6 5.2 7.4 0.4 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_13 PF18508.1 EFI26581.1 - 0.023 14.3 0.2 0.094 12.3 0.1 2.0 2 0 0 2 2 2 0 Zinc finger domain zf-met PF12874.7 EFI26581.1 - 0.036 14.5 1.8 6 7.4 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 EFI26581.1 - 0.056 13.5 4.6 0.32 11.2 0.2 3.3 2 1 1 3 3 3 0 Zic proteins zinc finger domain Zap1_zf2 PF18217.1 EFI26581.1 - 0.08 12.9 11.4 0.073 13.1 3.6 2.6 2 0 0 2 2 2 0 Zap1 zinc finger 2 DUF4726 PF15855.5 EFI26581.1 - 1.9 8.7 6.7 3 8.1 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) AAA_22 PF13401.6 EFI26583.1 - 0.0024 18.1 0.0 0.0046 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Surp PF01805.20 EFI26583.1 - 0.052 13.6 0.5 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Surp module Ald_Xan_dh_C2 PF02738.18 EFI26583.1 - 0.1 11.0 0.3 0.15 10.4 0.3 1.1 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase AAA_16 PF13191.6 EFI26583.1 - 0.16 12.3 2.8 0.42 11.0 2.8 1.7 1 1 0 1 1 1 0 AAA ATPase domain DRY_EERY PF09750.9 EFI26583.1 - 1.3 9.3 12.2 18 5.6 12.2 2.5 1 1 0 1 1 1 0 Alternative splicing regulator CCDC53 PF10152.9 EFI26583.1 - 7.2 7.0 9.0 1 9.8 4.0 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Lactamase_B PF00753.27 EFI26584.1 - 2.8e-06 27.5 0.6 5.1e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EFI26584.1 - 1.2e-05 24.9 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FHA PF00498.26 EFI26588.1 - 0.0099 16.2 0.2 0.058 13.8 0.2 2.1 1 1 0 1 1 1 1 FHA domain ABC1 PF03109.16 EFI26591.1 - 1.7e-23 83.0 2.6 7.7e-23 80.9 2.6 2.0 1 1 0 1 1 1 1 ABC1 family APH PF01636.23 EFI26591.1 - 0.019 14.9 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sacchrp_dh_C PF16653.5 EFI26592.1 - 4.4e-81 272.9 0.0 7e-81 272.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EFI26592.1 - 8.7e-16 58.4 0.0 1.5e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 EFI26592.1 - 2.3e-12 47.4 0.0 1.2e-11 45.0 0.0 2.2 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EFI26592.1 - 0.002 17.4 0.0 0.096 12.0 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 EFI26592.1 - 0.18 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RAP1 PF07218.11 EFI26592.1 - 2.7 6.2 6.5 4.1 5.6 6.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DHHC PF01529.20 EFI26603.1 - 2.3 8.3 6.5 3.1 7.9 6.2 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase AT_hook PF02178.19 EFI26605.1 - 0.0012 18.5 11.8 0.053 13.4 2.1 2.4 2 0 0 2 2 2 2 AT hook motif DUF570 PF04489.13 EFI26605.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Fasciclin PF02469.22 EFI26608.1 - 3.4e-25 88.7 0.5 1.4e-14 54.4 0.1 3.2 3 0 0 3 3 3 2 Fasciclin domain Ubiq_cyt_C_chap PF03981.12 EFI26612.1 - 0.066 13.3 0.0 0.07 13.2 0.0 1.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone GMC_oxred_N PF00732.19 EFI26614.1 - 1e-52 179.4 0.0 1.5e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EFI26614.1 - 7.5e-33 114.1 0.1 1.2e-32 113.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EFI26614.1 - 1.7e-06 27.4 1.0 0.00062 19.0 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EFI26614.1 - 0.00017 21.7 0.6 0.00049 20.3 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EFI26614.1 - 0.00025 20.2 0.3 0.00043 19.5 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EFI26614.1 - 0.00039 19.7 0.1 0.0029 16.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EFI26614.1 - 0.00077 19.1 2.0 0.0011 18.7 1.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EFI26614.1 - 0.0011 18.3 0.3 0.0021 17.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EFI26614.1 - 0.017 14.4 0.5 0.31 10.3 0.5 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EFI26614.1 - 0.1 11.6 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 EFI26614.1 - 0.17 10.5 1.0 0.45 9.1 0.4 1.8 2 0 0 2 2 2 0 HI0933-like protein Ntox24 PF15529.6 EFI26617.1 - 0.024 15.0 0.3 0.028 14.7 0.3 1.1 1 0 0 1 1 1 0 Bacterial toxin 24 TcdA_TcdB_pore PF12920.7 EFI26617.1 - 0.18 10.0 0.0 0.2 9.9 0.0 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain p450 PF00067.22 EFI26618.1 - 1.5e-65 221.7 0.0 2e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_halogenase PF04820.14 EFI26619.1 - 1.5e-28 99.8 0.2 2.3e-14 53.1 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EFI26619.1 - 2.6e-15 56.5 0.0 8.4e-15 54.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EFI26619.1 - 5.4e-07 29.7 0.1 1.8e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EFI26619.1 - 4.1e-06 26.6 0.0 0.00012 21.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EFI26619.1 - 5.2e-06 25.9 0.0 1.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EFI26619.1 - 1.2e-05 24.9 0.0 2.9e-05 23.6 0.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EFI26619.1 - 8.7e-05 21.8 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EFI26619.1 - 0.00012 22.6 0.0 0.0016 19.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EFI26619.1 - 0.00029 19.7 0.0 0.00046 19.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EFI26619.1 - 0.00045 19.4 0.1 0.00089 18.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EFI26619.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EFI26619.1 - 0.023 13.7 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EFI26619.1 - 0.028 13.7 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 EFI26619.1 - 0.046 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EFI26619.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EFI26619.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EFI26619.1 - 0.16 12.5 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sad1_UNC PF07738.13 EFI26622.1 - 1.7e-05 24.8 0.0 3.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Patched PF02460.18 EFI26623.1 - 0.036 12.1 0.1 0.046 11.8 0.1 1.1 1 0 0 1 1 1 0 Patched family FlxA PF14282.6 EFI26624.1 - 0.091 12.8 2.0 0.11 12.5 2.0 1.2 1 0 0 1 1 1 0 FlxA-like protein XPG_I PF00867.18 EFI26625.1 - 9.8e-15 54.7 0.0 1.8e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EFI26625.1 - 0.00017 22.0 0.0 0.00099 19.5 0.0 2.3 2 1 0 2 2 2 1 XPG N-terminal domain GEN1_C PF18380.1 EFI26625.1 - 0.14 13.0 0.1 0.96 10.4 0.0 2.1 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Pre-SET PF05033.16 EFI26627.1 - 2.5e-15 57.1 2.8 2.5e-15 57.1 2.8 2.2 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 EFI26627.1 - 8e-12 45.9 0.4 3e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 SET domain ATF7IP_BD PF16788.5 EFI26627.1 - 0.44 10.6 6.5 0.84 9.7 6.5 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain ATP11 PF06644.11 EFI26627.1 - 0.52 10.0 5.6 0.88 9.3 5.6 1.3 1 0 0 1 1 1 0 ATP11 protein DUF4554 PF15091.6 EFI26627.1 - 2.7 6.8 7.5 4.2 6.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CCD PF07860.11 EFI26628.1 - 0.091 12.8 0.4 0.27 11.3 0.4 1.8 1 0 0 1 1 1 0 WisP family C-Terminal Region DUF1908 PF08926.11 EFI26629.1 - 0.031 13.4 0.1 0.066 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Plavaka PF18759.1 EFI26632.1 - 1.2e-39 136.4 0.4 3.2e-39 135.0 0.0 1.8 2 0 0 2 2 2 1 Plavaka transposase UQ_con PF00179.26 EFI26637.1 - 3.8e-36 123.8 0.0 1e-34 119.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.6 EFI26638.1 - 2.3e-12 47.0 6.5 3.5e-12 46.4 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EFI26638.1 - 6.4e-07 29.1 5.3 1e-06 28.5 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EFI26638.1 - 2.6e-06 27.1 7.8 4.2e-06 26.5 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EFI26638.1 - 2.9e-06 27.0 3.9 4.3e-06 26.5 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EFI26638.1 - 3.5e-06 26.9 4.6 7.1e-06 26.0 4.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EFI26638.1 - 1.2e-05 25.5 7.5 2.8e-05 24.3 7.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EFI26638.1 - 1.2e-05 25.1 3.2 1.8e-05 24.6 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EFI26638.1 - 0.00034 20.6 1.4 0.00061 19.8 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EFI26638.1 - 0.00089 19.3 3.3 0.0015 18.6 3.3 1.4 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 EFI26638.1 - 0.0013 18.3 1.9 0.0023 17.5 1.9 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EFI26638.1 - 0.0016 18.2 1.0 0.0016 18.2 1.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-Nse PF11789.8 EFI26638.1 - 0.0063 16.3 1.8 0.014 15.2 1.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EFI26638.1 - 0.0064 16.3 7.9 0.17 11.8 8.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Secretin_N_2 PF07655.13 EFI26638.1 - 0.017 15.6 7.1 0.017 15.6 7.1 3.8 3 0 0 3 3 3 0 Secretin N-terminal domain zf-RING_4 PF14570.6 EFI26638.1 - 0.075 12.8 6.6 0.14 12.0 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EFI26638.1 - 0.24 11.6 5.2 1.2 9.3 5.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EFI26638.1 - 0.27 11.2 3.9 0.47 10.4 3.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 EFI26638.1 - 0.99 9.5 2.3 2.3 8.3 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger zf-P11 PF03854.14 EFI26638.1 - 1.5 8.5 4.2 1 9.1 1.2 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-RING-like PF08746.11 EFI26638.1 - 7 7.1 7.6 0.88 9.9 3.2 1.7 2 0 0 2 2 2 0 RING-like domain GMC_oxred_N PF00732.19 EFI26641.1 - 5.7e-66 222.9 0.0 7.1e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EFI26641.1 - 3.4e-08 34.1 0.0 8.8e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EFI26641.1 - 1.4e-06 28.4 0.1 0.00012 22.2 0.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EFI26641.1 - 5.7e-05 22.3 0.1 8.9e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EFI26641.1 - 8.4e-05 21.8 0.0 0.036 13.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EFI26641.1 - 0.00018 21.2 0.2 0.0091 15.6 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EFI26641.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EFI26641.1 - 0.0044 16.3 0.0 0.058 12.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EFI26641.1 - 0.018 13.9 0.3 0.048 12.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.18 EFI26641.1 - 0.25 11.6 0.0 0.47 10.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.19 EFI26642.1 - 9.6e-61 205.7 0.0 1.6e-60 205.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EFI26642.1 - 8.3e-31 107.4 0.1 1.6e-30 106.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EFI26642.1 - 0.012 15.9 0.0 0.056 13.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3135 PF11333.8 EFI26644.1 - 0.2 11.9 0.0 5.3 7.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Cyt-b5 PF00173.28 EFI26645.1 - 5.3e-14 52.1 0.0 9.1e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EFI26645.1 - 3.2e-06 27.2 6.4 5e-06 26.5 6.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase HGTP_anticodon PF03129.20 EFI26646.1 - 6.8e-19 67.8 0.0 1.8e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EFI26646.1 - 2.9e-07 30.6 0.0 4.5e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Gluconate_2-dh3 PF13618.6 EFI26649.1 - 0.064 13.5 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 KDZ PF18758.1 EFI26650.1 - 1.7e-45 155.3 1.2 3e-45 154.6 1.2 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI26650.1 - 7.5e-17 61.4 0.0 2.1e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases DUF4709 PF15821.5 EFI26650.1 - 0.082 13.2 1.7 0.3 11.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) AAA_13 PF13166.6 EFI26650.1 - 6.1 5.4 8.6 1.1 7.8 2.8 2.0 2 0 0 2 2 2 0 AAA domain FeoB_associated PF12669.7 EFI26651.1 - 0.2 12.1 7.0 0.19 12.1 7.0 1.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2970 PF11174.8 EFI26651.1 - 4.5 7.2 10.0 4.9 7.1 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF3827 PF12877.7 EFI26651.1 - 6.2 5.1 6.0 5.3 5.3 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Synaptobrevin PF00957.21 EFI26651.1 - 9.7 6.1 9.7 11 5.9 9.7 1.0 1 0 0 1 1 1 0 Synaptobrevin Synaptobrevin PF00957.21 EFI26652.1 - 1.1e-21 76.4 0.3 1.6e-21 75.9 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Pkinase PF00069.25 EFI26653.1 - 9e-58 195.7 0.0 1.3e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI26653.1 - 8.6e-29 100.6 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EFI26653.1 - 4.5e-11 42.6 0.0 6.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EFI26653.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EFI26653.1 - 0.042 12.8 0.0 0.042 12.8 0.0 2.6 3 0 0 3 3 3 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EFI26653.1 - 0.26 10.0 0.0 0.26 10.0 0.0 2.8 3 0 0 3 3 3 0 Fungal protein kinase CCDC-167 PF15188.6 EFI26654.1 - 0.018 15.4 4.3 0.038 14.3 4.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4763 PF15960.5 EFI26654.1 - 0.029 13.7 1.1 0.044 13.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) ABC_tran_CTD PF16326.5 EFI26654.1 - 0.064 13.5 10.3 0.33 11.2 2.4 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain Prefoldin_2 PF01920.20 EFI26654.1 - 0.63 10.0 5.7 4.1 7.4 1.5 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.6 EFI26654.1 - 0.95 9.9 6.5 14 6.2 1.8 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 EFI26654.1 - 0.96 9.5 6.4 0.12 12.3 2.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 EFI26654.1 - 1.3 9.7 6.6 0.27 11.9 0.7 2.7 2 1 1 3 3 3 0 SlyX Takusan PF04822.13 EFI26654.1 - 1.9 8.5 5.2 1.9 8.4 0.1 2.4 2 0 0 2 2 2 0 Takusan Tropomyosin PF00261.20 EFI26654.1 - 2 7.7 8.7 0.41 10.0 1.3 2.1 2 0 0 2 2 2 0 Tropomyosin PRKG1_interact PF15898.5 EFI26654.1 - 2.5 9.0 7.9 0.53 11.2 4.2 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain XhlA PF10779.9 EFI26654.1 - 5.5 7.3 8.1 5.6 7.3 1.3 2.8 2 1 0 2 2 2 0 Haemolysin XhlA Xin PF08043.12 EFI26656.1 - 0.18 11.5 0.4 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Xin repeat Amino_oxidase PF01593.24 EFI26657.1 - 1.1e-40 140.3 0.1 3.5e-40 138.6 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EFI26657.1 - 1.7e-11 44.2 0.6 5.4e-11 42.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EFI26657.1 - 0.0015 17.9 0.9 0.0023 17.2 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EFI26657.1 - 0.0061 15.7 0.3 0.0097 15.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EFI26657.1 - 0.029 13.7 0.7 0.051 12.9 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EFI26657.1 - 0.05 12.9 0.5 0.086 12.1 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EFI26657.1 - 0.11 11.1 0.3 0.17 10.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EFI26657.1 - 0.19 10.9 0.1 0.4 9.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ank_2 PF12796.7 EFI26658.1 - 1.2e-83 275.8 10.7 2.4e-14 53.7 0.0 6.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.30 EFI26658.1 - 1.5e-45 151.7 1.3 0.0004 20.7 0.0 11.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.6 EFI26658.1 - 6.4e-45 151.0 2.5 1.5e-08 35.0 0.0 7.9 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EFI26658.1 - 8e-44 142.6 1.9 0.00011 22.3 0.0 12.1 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 EFI26658.1 - 4.2e-33 113.0 13.3 0.001 19.3 0.1 10.4 1 1 9 10 10 10 10 Ankyrin repeats (many copies) Cyclin_N PF00134.23 EFI26658.1 - 0.043 13.6 0.0 10 5.9 0.0 3.1 1 1 1 2 2 2 0 Cyclin, N-terminal domain RisS_PPD PF16524.5 EFI26658.1 - 0.058 13.6 0.0 3.6 7.9 0.0 3.2 2 0 0 2 2 2 0 Periplasmic domain of Sensor histidine kinase RisS BRCA-2_helical PF09169.10 EFI26658.1 - 0.15 11.7 0.1 16 5.1 0.0 3.0 3 0 0 3 3 3 0 BRCA2, helical NapD PF03927.13 EFI26658.1 - 0.17 12.0 0.9 8.8 6.5 0.0 4.0 4 1 1 5 5 5 0 NapD protein Putative_PNPOx PF01243.20 EFI26661.1 - 1.6e-05 25.0 0.0 0.039 14.1 0.0 2.3 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 EFI26662.1 - 4.3e-23 82.0 0.0 1.9e-21 76.6 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI26662.1 - 9.4e-09 34.9 0.0 6.9e-06 25.5 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RRM_1 PF00076.22 EFI26663.1 - 3.3e-10 39.7 0.1 1.4e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3915 PF13054.6 EFI26663.1 - 0.011 15.7 1.0 0.023 14.6 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GCP_N_terminal PF17681.1 EFI26669.1 - 1.8e-65 221.5 0.0 3.5e-65 220.6 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EFI26669.1 - 9.7e-59 199.3 9.8 9.7e-59 199.3 9.8 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal CUE PF02845.16 EFI26670.1 - 7.7e-11 41.5 0.0 1.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 EFI26670.1 - 0.037 14.1 0.3 0.097 12.7 0.1 1.7 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 DUF5470 PF17564.2 EFI26670.1 - 0.05 13.8 0.2 0.16 12.2 0.1 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5470) DUF724 PF05266.14 EFI26674.1 - 5.8 6.7 7.8 18 5.1 7.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Pox_RNA_Pol_19 PF05320.12 EFI26675.1 - 0.29 11.1 2.3 0.78 9.7 2.3 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4611 PF15387.6 EFI26675.1 - 1.9 8.7 10.8 0.3 11.3 4.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-RING_5 PF14634.6 EFI26676.1 - 5.3e-08 32.7 7.9 5.3e-08 32.7 7.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EFI26676.1 - 5.6e-08 33.0 9.7 1e-07 32.1 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EFI26676.1 - 8.6e-06 25.5 9.0 2.1e-05 24.3 9.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EFI26676.1 - 1.9e-05 24.6 11.2 2.6e-05 24.1 6.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EFI26676.1 - 0.00026 20.8 9.9 0.00059 19.6 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EFI26676.1 - 0.00066 19.5 10.9 0.0014 18.4 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EFI26676.1 - 0.00074 19.0 1.3 0.00074 19.0 1.3 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 EFI26676.1 - 0.0033 17.6 9.5 0.028 14.6 9.8 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EFI26676.1 - 0.0042 16.8 5.1 0.0085 15.8 5.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EFI26676.1 - 0.0079 16.0 8.5 0.016 15.0 8.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain UBZ_FAAP20 PF15750.5 EFI26676.1 - 0.031 14.2 1.4 0.061 13.3 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger DDRGK PF09756.9 EFI26676.1 - 0.045 13.3 3.9 0.066 12.8 3.9 1.1 1 0 0 1 1 1 0 DDRGK domain Phage_GPO PF05929.11 EFI26676.1 - 0.049 13.3 2.9 0.062 12.9 2.9 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2780 PF11075.8 EFI26676.1 - 0.072 13.2 3.8 0.16 12.1 2.9 2.0 1 1 2 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) DUF724 PF05266.14 EFI26676.1 - 0.084 12.7 4.3 0.11 12.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3039 PF11238.8 EFI26676.1 - 0.12 12.2 4.8 0.33 10.7 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) FYVE PF01363.21 EFI26676.1 - 0.15 12.2 6.6 0.077 13.1 3.1 2.4 2 1 0 2 2 2 0 FYVE zinc finger Spc7 PF08317.11 EFI26676.1 - 0.37 9.6 10.2 0.95 8.3 10.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein IBR PF01485.21 EFI26676.1 - 0.61 10.4 5.5 2.1 8.6 5.6 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 EFI26676.1 - 0.97 9.4 7.5 3.5 7.6 7.5 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein HSCB_C PF07743.13 EFI26676.1 - 5.6 7.5 9.0 5.4 7.6 6.7 2.0 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain zf-rbx1 PF12678.7 EFI26676.1 - 5.6 7.3 8.9 3.6 7.9 6.5 2.0 2 0 0 2 2 1 0 RING-H2 zinc finger domain Pheromone PF08015.11 EFI26679.1 - 0.026 15.6 2.9 0.038 15.0 0.2 1.9 1 1 1 2 2 2 0 Fungal mating-type pheromone LRR_4 PF12799.7 EFI26681.1 - 2.6 8.6 6.6 39 4.8 0.1 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Hydrolase_4 PF12146.8 EFI26682.1 - 5.4e-13 48.8 0.2 1.5e-12 47.3 0.2 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EFI26682.1 - 1.2e-11 45.7 2.1 1.2e-11 45.7 2.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EFI26682.1 - 3.2e-10 40.1 0.2 5.1e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EFI26682.1 - 6.5e-07 29.4 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EFI26682.1 - 0.00061 19.7 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 EFI26682.1 - 0.0016 18.0 0.1 0.0046 16.5 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF3089 PF11288.8 EFI26682.1 - 0.0069 16.0 0.1 1.6 8.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3089) Thioesterase PF00975.20 EFI26682.1 - 0.011 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.16 EFI26682.1 - 0.013 15.3 0.1 0.75 9.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.12 EFI26682.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) COesterase PF00135.28 EFI26682.1 - 0.023 13.6 0.1 0.032 13.1 0.1 1.2 1 0 0 1 1 1 0 Carboxylesterase family Ser_hydrolase PF06821.13 EFI26682.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Lipase PF00151.19 EFI26682.1 - 0.054 12.8 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipase PGAP1 PF07819.13 EFI26682.1 - 0.13 11.9 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein FSH1 PF03959.13 EFI26682.1 - 0.21 11.2 0.1 0.87 9.2 0.0 1.8 1 1 1 2 2 2 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 EFI26682.1 - 0.22 11.0 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ABC_membrane PF00664.23 EFI26686.1 - 1.3e-21 77.5 5.7 2.3e-21 76.7 5.7 1.3 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EFI26687.1 - 6.2e-42 143.4 0.0 2.3e-29 102.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EFI26687.1 - 1.4e-35 123.2 14.8 2.1e-35 122.7 14.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EFI26687.1 - 2.1e-07 30.6 0.8 0.0021 17.5 0.1 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EFI26687.1 - 0.0018 18.3 0.1 0.0047 17.0 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EFI26687.1 - 0.017 15.5 0.1 0.05 14.0 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EFI26687.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EFI26687.1 - 0.058 13.2 0.6 2.4 7.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 EFI26687.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MeaB PF03308.16 EFI26687.1 - 0.099 11.6 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EFI26687.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 EFI26687.1 - 0.14 12.2 0.1 0.38 10.8 0.1 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain SbcCD_C PF13558.6 EFI26687.1 - 0.45 10.8 4.2 3.9 7.8 0.1 3.8 4 1 0 4 4 4 0 Putative exonuclease SbcCD, C subunit OppC_N PF12911.7 EFI26687.1 - 1.6 8.7 0.0 1.6 8.7 0.0 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C RNA_polI_A34 PF08208.11 EFI26688.1 - 0.071 13.2 5.1 36 4.4 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Plavaka PF18759.1 EFI26689.1 - 6.2e-11 42.1 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_4 PF13894.6 EFI26689.1 - 1.5 9.9 4.0 4.6 8.3 4.0 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EFI26689.1 - 9.8 6.9 6.3 2.3 8.8 2.5 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type SAE2 PF08573.10 EFI26691.1 - 2.6e-22 80.0 2.3 2.6e-22 80.0 2.3 3.2 3 1 0 3 3 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Rootletin PF15035.6 EFI26691.1 - 0.0015 18.6 10.5 0.004 17.2 10.5 1.8 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 EFI26691.1 - 0.0034 16.8 8.6 0.0034 16.8 8.6 2.3 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 EFI26691.1 - 0.0037 17.3 9.7 0.042 14.0 0.9 2.7 2 0 0 2 2 2 2 bZIP transcription factor YabA PF06156.13 EFI26691.1 - 0.019 15.6 5.9 0.022 15.4 0.6 2.7 2 1 0 2 2 2 0 Initiation control protein YabA TACC_C PF05010.14 EFI26691.1 - 0.027 14.3 10.3 0.097 12.5 5.3 2.5 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DHR10 PF18595.1 EFI26691.1 - 0.031 14.3 0.7 0.031 14.3 0.7 3.6 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 EFI26691.1 - 0.038 12.9 6.3 0.04 12.8 5.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein FlgN PF05130.12 EFI26691.1 - 0.042 14.4 4.5 0.093 13.2 0.5 2.3 1 1 1 2 2 2 0 FlgN protein BAR_3 PF16746.5 EFI26691.1 - 0.096 12.4 5.1 0.11 12.1 1.7 2.2 1 1 1 2 2 2 0 BAR domain of APPL family DUF3450 PF11932.8 EFI26691.1 - 0.098 11.9 7.5 0.079 12.3 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Nup54 PF13874.6 EFI26691.1 - 0.16 12.1 7.4 0.25 11.5 0.2 2.9 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.11 EFI26691.1 - 0.21 12.0 5.7 4.9 7.6 0.4 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spectrin PF00435.21 EFI26691.1 - 0.47 11.0 5.5 0.8 10.2 0.4 3.1 3 0 0 3 3 3 0 Spectrin repeat KASH_CCD PF14662.6 EFI26691.1 - 0.67 9.8 10.5 0.14 11.9 2.8 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH MCC-bdg_PDZ PF10506.9 EFI26691.1 - 0.7 10.0 2.7 15 5.7 0.0 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TSC22 PF01166.18 EFI26691.1 - 1.3 9.4 4.1 0.91 9.9 0.9 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 EFI26691.1 - 1.4 9.2 8.1 3.9 7.8 0.5 3.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain SHE3 PF17078.5 EFI26691.1 - 1.6 8.4 8.9 6.4 6.4 0.4 2.6 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 EFI26691.1 - 1.6 8.8 7.3 1.5 8.9 0.7 2.9 2 0 0 2 2 2 0 TolA binding protein trimerisation CENP-Q PF13094.6 EFI26691.1 - 1.9 8.6 14.3 5.1 7.3 2.8 2.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.11 EFI26691.1 - 3.3 6.5 15.5 0.12 11.3 7.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.19 EFI26691.1 - 4.6 5.0 5.1 9.8 3.9 5.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Csm1_N PF18504.1 EFI26691.1 - 5.1 7.5 7.8 16 5.9 0.3 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain ZapB PF06005.12 EFI26691.1 - 6.2 7.3 8.0 4.9 7.7 3.0 2.8 1 1 1 2 2 2 0 Cell division protein ZapB NRBF2 PF08961.10 EFI26691.1 - 8 6.0 11.1 7.7 6.1 0.8 2.9 1 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Plavaka PF18759.1 EFI26693.1 - 4.8e-52 177.2 0.0 6.4e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Ndc1_Nup PF09531.10 EFI26696.1 - 6.6e-88 295.9 0.1 8e-88 295.7 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup eIF3_subunit PF08597.10 EFI26696.1 - 0.14 12.1 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF2070 PF09843.9 EFI26696.1 - 0.28 9.4 11.2 0.43 8.8 11.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SKN1 PF03935.15 EFI26697.1 - 4.1e-181 602.8 3.9 8.3e-180 598.5 3.9 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3471 PF11954.8 EFI26697.1 - 0.077 13.5 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) SPX PF03105.19 EFI26697.1 - 2.1 8.2 11.0 3.4 7.5 11.0 1.4 1 0 0 1 1 1 0 SPX domain CC PF04942.14 EFI26699.1 - 0.17 12.1 1.0 0.28 11.4 0.4 1.6 2 0 0 2 2 2 0 CC domain SKN1 PF03935.15 EFI26700.1 - 9e-05 21.1 0.5 0.00099 17.6 0.0 2.2 1 1 1 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) CDC45 PF02724.14 EFI26700.1 - 9.6e-05 20.9 22.2 9.6e-05 20.9 22.2 1.9 2 0 0 2 2 2 1 CDC45-like protein Pex14_N PF04695.13 EFI26700.1 - 0.19 12.4 0.0 0.19 12.4 0.0 4.7 4 1 1 5 5 5 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 EFI26700.1 - 1.5 8.5 35.8 0.062 13.1 27.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Pkinase PF00069.25 EFI26704.1 - 3.2e-34 118.5 0.0 5.1e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI26704.1 - 1.2e-08 34.6 0.0 3.2e-07 29.9 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI26704.1 - 0.018 13.8 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EFI26704.1 - 0.089 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase F-box PF00646.33 EFI26705.1 - 0.0042 16.9 0.4 0.011 15.6 0.4 1.8 1 0 0 1 1 1 1 F-box domain KDZ PF18758.1 EFI26707.1 - 2.6e-45 154.7 1.3 4e-45 154.2 1.3 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI26707.1 - 2e-21 76.1 0.7 5.7e-21 74.7 0.1 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases ERM PF00769.19 EFI26709.1 - 0.00015 21.7 2.1 0.00017 21.5 2.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Spc7 PF08317.11 EFI26709.1 - 0.00036 19.5 1.2 0.00042 19.3 1.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 EFI26709.1 - 0.0005 19.3 1.9 0.00059 19.0 1.9 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 MPS2 PF17060.5 EFI26709.1 - 0.0031 16.9 0.3 0.0035 16.7 0.3 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 SKA2 PF16740.5 EFI26709.1 - 0.0038 17.0 1.5 0.024 14.4 1.5 1.7 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Docking PF08990.11 EFI26709.1 - 0.0051 16.4 0.6 0.046 13.3 0.0 2.6 2 0 0 2 2 2 1 Erythronolide synthase docking H-kinase_dim PF02895.14 EFI26709.1 - 0.009 16.4 2.5 0.011 16.1 1.9 1.4 1 1 0 1 1 1 1 Signal transducing histidine kinase, homodimeric domain DUF812 PF05667.11 EFI26709.1 - 0.0094 14.9 0.2 0.01 14.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) APG6_N PF17675.1 EFI26709.1 - 0.01 16.4 1.8 0.012 16.1 1.8 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C4H2 PF10146.9 EFI26709.1 - 0.011 16.1 0.1 0.013 15.9 0.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein OmpH PF03938.14 EFI26709.1 - 0.013 15.9 1.0 0.016 15.5 1.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HrpB7 PF09486.10 EFI26709.1 - 0.013 15.9 4.5 0.02 15.3 4.5 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Apolipoprotein PF01442.18 EFI26709.1 - 0.014 15.3 3.8 0.019 14.8 3.8 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DHR10 PF18595.1 EFI26709.1 - 0.019 15.0 7.4 0.026 14.6 7.4 1.1 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Laminin_II PF06009.12 EFI26709.1 - 0.02 14.9 0.9 0.027 14.5 0.9 1.1 1 0 0 1 1 1 0 Laminin Domain II COG2 PF06148.11 EFI26709.1 - 0.024 14.7 2.0 0.039 14.1 2.0 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 BicD PF09730.9 EFI26709.1 - 0.027 12.9 2.9 0.034 12.6 2.9 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Phage_GP20 PF06810.11 EFI26709.1 - 0.027 14.3 0.9 0.036 13.9 0.9 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.12 EFI26709.1 - 0.028 14.5 5.2 0.038 14.1 5.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ZnuA PF01297.17 EFI26709.1 - 0.034 13.6 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF4200 PF13863.6 EFI26709.1 - 0.046 14.1 6.4 0.065 13.6 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CotH PF08757.11 EFI26709.1 - 0.054 13.0 0.3 0.069 12.7 0.3 1.1 1 0 0 1 1 1 0 CotH kinase protein Exonuc_VII_L PF02601.15 EFI26709.1 - 0.054 13.0 0.2 0.054 13.0 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DLP_helical PF18709.1 EFI26709.1 - 0.057 12.6 4.4 0.079 12.2 4.4 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Fusion_gly PF00523.18 EFI26709.1 - 0.059 11.6 0.6 0.15 10.2 0.3 1.6 1 1 1 2 2 2 0 Fusion glycoprotein F0 IFT57 PF10498.9 EFI26709.1 - 0.059 12.3 2.9 0.077 12.0 2.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 EzrA PF06160.12 EFI26709.1 - 0.063 11.4 3.2 0.081 11.1 3.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fmp27_WPPW PF10359.9 EFI26709.1 - 0.094 11.6 0.4 0.11 11.4 0.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ADIP PF11559.8 EFI26709.1 - 0.13 12.3 6.6 0.18 11.9 6.6 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding KxDL PF10241.9 EFI26709.1 - 0.13 12.5 2.8 0.21 11.9 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4407 PF14362.6 EFI26709.1 - 0.16 11.3 0.7 0.19 11.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EFI26709.1 - 0.18 11.9 2.7 0.23 11.6 2.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Het-C PF07217.11 EFI26709.1 - 0.19 10.3 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Vps51 PF08700.11 EFI26709.1 - 0.26 11.4 2.6 0.21 11.7 0.7 1.8 1 1 1 2 2 2 0 Vps51/Vps67 FemAB PF02388.16 EFI26709.1 - 0.33 9.8 1.6 0.43 9.4 1.6 1.1 1 0 0 1 1 1 0 FemAB family GrpE PF01025.19 EFI26709.1 - 0.49 10.0 4.2 0.66 9.6 4.2 1.1 1 0 0 1 1 1 0 GrpE UPF0449 PF15136.6 EFI26709.1 - 1.6 9.3 7.0 0.38 11.3 1.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 DUF1043 PF06295.12 EFI26709.1 - 7.1 6.6 7.3 11 6.1 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) DUF2610 PF11020.8 EFI26710.1 - 0.089 12.7 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) HisKA PF00512.25 EFI26710.1 - 0.13 12.4 0.9 0.57 10.3 0.9 2.0 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Aft1_HRA PF11786.8 EFI26713.1 - 0.071 13.5 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 Aft1 HRA domain DNase_NucA_NucB PF14040.6 EFI26717.1 - 0.00033 21.0 0.0 0.00055 20.3 0.0 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB KDZ PF18758.1 EFI26719.1 - 4.4e-45 154.0 0.0 8.5e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI26719.1 - 9.2e-21 74.0 0.1 2.4e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EFI26719.1 - 0.0028 17.8 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases Defensin_5 PF18251.1 EFI26722.1 - 5.6e-23 80.7 19.6 1.7e-22 79.2 19.6 1.9 1 0 0 1 1 1 1 Fungal defensin Copsin CFEM PF05730.11 EFI26722.1 - 3.7e-05 23.7 3.2 3.7e-05 23.7 3.2 2.6 2 1 0 2 2 2 1 CFEM domain DUF1996 PF09362.10 EFI26723.1 - 5.8e-41 141.0 0.1 1e-26 94.4 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) ABC_tran PF00005.27 EFI26724.1 - 6.5e-44 149.8 0.9 6.1e-25 88.3 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EFI26724.1 - 3.6e-12 46.7 2.4 0.0043 16.9 1.8 4.5 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EFI26724.1 - 8.2e-10 38.5 0.4 7.8e-07 28.7 0.0 3.7 3 2 0 3 3 2 1 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 EFI26724.1 - 3.5e-08 33.4 4.3 3.5e-08 33.4 4.3 3.1 3 0 0 3 3 2 1 ABC transporter RsgA_GTPase PF03193.16 EFI26724.1 - 4.8e-08 33.1 0.3 0.0048 16.8 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EFI26724.1 - 6e-07 29.1 0.2 0.0032 17.2 0.0 2.9 2 1 1 3 3 3 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EFI26724.1 - 1.8e-05 25.4 0.2 0.033 14.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EFI26724.1 - 2.1e-05 24.6 0.1 0.013 15.5 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EFI26724.1 - 4.2e-05 23.9 0.0 0.12 12.8 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 EFI26724.1 - 0.00011 22.2 0.0 0.58 10.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 EFI26724.1 - 0.00012 22.6 0.2 0.069 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EFI26724.1 - 0.00024 21.1 0.1 0.59 10.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EFI26724.1 - 0.00051 20.5 0.0 1.2 9.6 0.0 3.7 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EFI26724.1 - 0.0014 18.9 0.1 1.6 9.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EFI26724.1 - 0.0014 18.0 0.3 1.1 8.5 0.1 3.2 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_14 PF13173.6 EFI26724.1 - 0.0018 18.3 0.0 5 7.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EFI26724.1 - 0.0018 18.0 0.0 2.7 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EFI26724.1 - 0.0021 17.8 0.4 0.17 11.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain DAP3 PF10236.9 EFI26724.1 - 0.0038 16.5 0.1 1.7 7.7 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 EFI26724.1 - 0.0051 16.3 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EFI26724.1 - 0.0053 17.0 0.0 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EFI26724.1 - 0.0082 16.1 0.0 0.08 12.9 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EFI26724.1 - 0.011 15.2 0.5 0.88 8.9 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FeoB_N PF02421.18 EFI26724.1 - 0.015 14.8 1.3 0.27 10.7 0.0 2.8 3 1 0 3 3 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 EFI26724.1 - 0.036 14.6 2.0 1.6 9.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EFI26724.1 - 0.037 13.6 0.0 2.8 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EFI26724.1 - 0.051 12.8 0.0 4.9 6.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 EFI26724.1 - 0.052 13.8 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 EFI26724.1 - 0.055 13.4 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Tom22 PF04281.13 EFI26724.1 - 0.058 13.2 1.2 0.29 10.9 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 ATP-synt_ab PF00006.25 EFI26724.1 - 0.064 12.9 0.0 0.64 9.6 0.0 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.17 EFI26724.1 - 0.069 12.9 0.0 8.3 6.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EFI26724.1 - 0.071 13.3 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.23 EFI26725.1 - 9.5e-14 51.3 0.2 1.5e-13 50.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Med22 PF06179.12 EFI26727.1 - 0.05 13.8 0.6 0.12 12.7 0.5 1.7 1 1 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex UBD PF16455.5 EFI26727.1 - 0.15 12.4 1.1 13 6.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-binding domain YidD PF01809.18 EFI26730.1 - 0.054 13.4 2.0 4.4 7.3 1.6 2.9 2 1 0 2 2 2 0 Putative membrane protein insertion efficiency factor eIF3g PF12353.8 EFI26731.1 - 4.3e-43 146.7 3.4 6e-43 146.2 3.4 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EFI26731.1 - 2.7e-17 62.4 0.1 5e-17 61.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EFI26731.1 - 0.052 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EFI26731.1 - 0.18 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pox_A14 PF05767.12 EFI26734.1 - 0.017 15.2 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF5079 PF16882.5 EFI26737.1 - 5.6 6.8 14.1 0.71 9.7 8.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5079) NRIP1_repr_1 PF15687.5 EFI26741.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 DUF4710 PF15828.5 EFI26746.1 - 5.1 7.3 7.1 1.9 8.7 4.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) HUN PF08729.10 EFI26747.1 - 6.6e-05 22.8 2.1 0.00016 21.6 2.1 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Vps5 PF09325.10 EFI26752.1 - 4.7e-06 26.3 1.5 0.013 15.1 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Arnt_C PF18583.1 EFI26752.1 - 0.0012 18.4 0.4 0.49 10.0 0.1 2.3 2 0 0 2 2 2 2 Aminoarabinose transferase C-terminal domain IZUMO PF15005.6 EFI26752.1 - 0.017 15.7 0.5 3.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated SUFU PF05076.13 EFI26752.1 - 0.036 14.0 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) KDZ PF18758.1 EFI26753.1 - 6.1e-47 160.1 0.8 1.3e-46 159.1 0.2 1.8 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI26753.1 - 9.9e-24 83.6 0.1 3.9e-23 81.7 0.1 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EFI26753.1 - 0.0054 16.9 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases TFIIA_gamma_N PF02268.16 EFI26757.1 - 3.5e-25 87.8 0.1 5e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EFI26757.1 - 2.2e-22 78.9 0.2 3.7e-22 78.2 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Mito_fiss_reg PF05308.11 EFI26758.1 - 0.11 12.5 0.3 0.13 12.4 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EFI26758.1 - 0.38 10.2 2.2 0.41 10.1 2.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Polysacc_deac_1 PF01522.21 EFI26760.1 - 1.6e-30 105.6 0.0 3e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.25 EFI26761.1 - 2.1e-41 142.0 0.0 3.8e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EFI26761.1 - 8.7e-22 77.6 0.0 1.3e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI26761.1 - 0.0005 19.0 0.0 0.00087 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EFI26761.1 - 0.014 15.3 0.3 0.059 13.3 0.3 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M16_M PF16187.5 EFI26762.1 - 0.089 12.1 0.1 0.099 11.9 0.1 1.1 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 HhH-GPD PF00730.25 EFI26765.1 - 6.7e-13 49.0 0.0 2.7e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EFI26765.1 - 1.1e-08 35.1 1.1 3e-06 27.2 0.1 3.7 3 1 0 3 3 3 1 NUDIX domain HHH PF00633.23 EFI26765.1 - 3.6e-05 23.4 0.0 0.00012 21.7 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif Coilin_N PF15862.5 EFI26765.1 - 0.28 11.0 5.2 0.2 11.5 0.8 2.3 2 0 0 2 2 2 0 Coilin N-terminus DUF3395 PF11875.8 EFI26766.1 - 2.1e-33 115.5 0.0 4.4e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EFI26766.1 - 4.1e-17 62.1 0.2 8.3e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Peptidase_C7 PF01830.18 EFI26768.1 - 0.0058 16.1 0.0 0.0059 16.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C7 family Cyt-b5 PF00173.28 EFI26769.1 - 1.4e-20 73.2 0.2 3.1e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EFI26769.1 - 1.4e-12 48.1 15.6 1.4e-12 48.1 15.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AMP-binding PF00501.28 EFI26771.1 - 1.4e-65 221.6 0.0 2.1e-65 221.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EFI26771.1 - 3.8e-63 213.1 0.0 6.8e-63 212.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 EFI26771.1 - 5.8e-13 48.3 0.0 2.8e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EFI26771.1 - 1.9e-10 40.9 0.0 5e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EFI26771.1 - 0.00055 20.9 0.0 0.0034 18.3 0.0 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 EFI26771.1 - 0.00058 19.4 0.0 0.0019 17.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EFI26771.1 - 0.03 13.3 0.0 2.3 7.2 0.0 2.7 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NARP1 PF12569.8 EFI26772.1 - 1.1e-147 493.1 14.2 1.9e-147 492.3 5.3 2.8 2 2 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EFI26772.1 - 2.1e-18 64.9 4.4 0.0056 16.7 0.0 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 EFI26772.1 - 3.3e-12 46.7 9.0 0.00069 20.1 0.1 5.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EFI26772.1 - 3.7e-12 46.0 14.5 0.015 16.1 0.0 8.8 7 2 3 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EFI26772.1 - 1.1e-11 45.2 12.3 0.0014 19.2 0.4 7.6 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EFI26772.1 - 1.6e-11 43.4 1.4 0.0055 16.8 0.0 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EFI26772.1 - 2.4e-09 37.3 7.4 0.026 14.8 0.0 5.1 5 1 0 5 5 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EFI26772.1 - 1.3e-08 34.3 7.9 0.003 17.3 0.2 7.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EFI26772.1 - 2.7e-08 33.4 0.1 0.0011 18.6 0.3 4.4 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.6 EFI26772.1 - 7.3e-07 28.8 3.1 0.19 11.8 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EFI26772.1 - 3.1e-05 24.2 5.3 2.9 8.8 0.1 5.0 5 0 0 5 5 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EFI26772.1 - 4.8e-05 23.5 4.2 2.9 8.2 0.1 4.9 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EFI26772.1 - 0.00026 21.4 8.2 2.4 9.0 0.2 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EFI26772.1 - 0.00058 20.1 0.9 15 6.3 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EFI26772.1 - 0.0074 16.3 4.4 17 5.5 0.1 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 EFI26772.1 - 0.022 14.2 6.9 0.43 9.9 2.4 2.8 3 0 0 3 3 3 0 MalT-like TPR region TPR_10 PF13374.6 EFI26772.1 - 0.024 14.5 3.5 8.9 6.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EFI26772.1 - 0.089 13.2 9.8 0.49 10.8 1.6 4.2 3 1 0 4 4 4 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 EFI26772.1 - 1.6 8.9 9.5 15 5.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TniB PF05621.11 EFI26773.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Bacterial TniB protein R3H PF01424.22 EFI26774.1 - 2e-12 46.9 0.2 3.4e-12 46.1 0.2 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EFI26774.1 - 1e-06 28.7 87.8 0.00027 20.9 9.7 14.8 17 1 0 17 17 17 7 NF-X1 type zinc finger CRIM PF16978.5 EFI26775.1 - 6.6e-45 152.7 0.3 1.9e-44 151.2 0.0 2.0 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EFI26775.1 - 1e-05 25.8 0.1 1.9e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EFI26775.1 - 0.0004 20.5 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 EFI26775.1 - 0.00041 20.4 0.0 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 1 Raf-like Ras-binding domain RA PF00788.23 EFI26775.1 - 0.0029 18.2 0.0 0.042 14.5 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SIN1_PH PF16979.5 EFI26776.1 - 5.4e-18 65.3 0.5 6.5e-18 65.0 0.5 1.1 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology FragX_IP PF05994.11 EFI26776.1 - 0.081 11.0 0.1 0.087 10.9 0.1 1.0 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Flg_hook PF02120.16 EFI26776.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK p450 PF00067.22 EFI26777.1 - 1.7e-62 211.7 0.0 2.6e-43 148.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF3849 PF12960.7 EFI26779.1 - 0.016 15.2 0.0 0.019 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) TEBP_beta PF07404.11 EFI26779.1 - 0.079 12.3 1.1 0.082 12.2 1.1 1.0 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) p450 PF00067.22 EFI26780.1 - 2.5e-58 198.0 0.0 8.1e-55 186.4 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 Cyt-b5 PF00173.28 EFI26781.1 - 3.8e-13 49.4 0.0 8.3e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cnd1 PF12717.7 EFI26781.1 - 0.035 14.1 0.0 5.4 7.0 0.0 2.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Mitochondr_Som1 PF11093.8 EFI26782.1 - 0.037 14.0 0.2 0.048 13.7 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DUF1768 PF08719.11 EFI26783.1 - 2.2e-44 151.6 0.1 4e-44 150.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) La PF05383.17 EFI26783.1 - 3.9e-17 62.0 0.0 7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 La domain S1-P1_nuclease PF02265.16 EFI26787.1 - 8.2e-15 55.3 0.0 1.8e-12 47.6 0.0 2.0 2 0 0 2 2 2 2 S1/P1 Nuclease MRPL52 PF18699.1 EFI26787.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Pmp3 PF01679.17 EFI26790.1 - 3e-23 81.7 11.9 3.7e-23 81.5 11.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.8 EFI26790.1 - 0.38 10.9 1.7 0.61 10.2 1.7 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal PIGA PF08288.12 EFI26801.1 - 5.6e-37 126.2 0.2 1.6e-36 124.7 0.2 1.9 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 EFI26801.1 - 1.3e-25 90.0 0.0 2.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EFI26801.1 - 3.3e-22 79.3 0.1 6.9e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EFI26801.1 - 1.7e-19 70.4 2.1 5e-19 68.9 2.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EFI26801.1 - 3.4e-06 27.6 0.1 9.9e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EFI26801.1 - 0.00083 19.7 0.0 0.002 18.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EFI26801.1 - 0.01 15.9 0.0 0.025 14.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like DAO PF01266.24 EFI26802.1 - 5.5e-34 118.3 0.8 7e-34 117.9 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EFI26802.1 - 0.074 13.3 3.2 0.62 10.3 0.8 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ChAPs PF09295.10 EFI26804.1 - 1e-106 357.3 3.9 5.2e-95 318.8 0.1 3.3 3 0 0 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EFI26804.1 - 3.7e-05 24.1 0.6 0.001 19.5 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EFI26804.1 - 0.0003 20.7 5.4 7.5 6.9 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EFI26804.1 - 0.0025 17.9 0.3 1.3 9.4 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EFI26804.1 - 0.012 16.3 0.7 51 5.1 0.0 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EFI26804.1 - 0.015 15.9 0.5 0.51 11.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EFI26804.1 - 0.05 13.8 0.1 0.45 10.8 0.1 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EFI26804.1 - 0.29 11.9 5.0 1.2e+02 3.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.10 EFI26806.1 - 1.8e-148 494.8 0.0 2.4e-146 487.8 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EFI26806.1 - 5.1e-08 33.3 0.4 0.00066 20.1 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EFI26806.1 - 1.2e-06 28.2 3.7 5 7.5 0.3 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EFI26806.1 - 5.2e-05 23.1 0.8 0.87 10.0 0.0 4.7 6 0 0 6 6 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EFI26806.1 - 0.00033 20.8 0.3 0.0096 16.1 0.2 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EFI26806.1 - 0.0031 18.2 4.0 33 5.7 0.0 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EFI26806.1 - 0.0041 17.7 1.4 0.31 11.7 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EFI26806.1 - 0.011 15.7 0.5 5.1 7.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EFI26806.1 - 0.019 14.2 1.4 5.1 6.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 EFI26806.1 - 0.025 13.5 0.1 0.53 9.1 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 EFI26806.1 - 0.027 14.8 3.0 7.9 6.8 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EFI26806.1 - 0.079 12.7 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 EFI26806.1 - 0.092 12.6 6.1 47 4.0 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EFI26806.1 - 0.1 13.0 0.0 4.5 7.7 0.0 2.4 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_6 PF13174.6 EFI26806.1 - 0.11 13.2 8.9 93 4.0 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.17 EFI26806.1 - 0.17 12.3 0.9 5.1 7.5 0.0 3.2 4 0 0 4 4 3 0 Bacterial transcriptional activator domain SPATA24 PF15175.6 EFI26807.1 - 0.0046 16.9 2.2 0.0078 16.1 2.2 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 F-box PF00646.33 EFI26808.1 - 3.7e-13 49.0 7.4 5.6e-06 26.1 0.7 2.7 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 EFI26808.1 - 1e-07 31.7 9.8 0.0023 17.8 1.6 2.9 2 0 0 2 2 2 2 F-box-like ECM1 PF05782.11 EFI26808.1 - 0.24 10.3 2.9 8.5 5.2 0.1 2.4 3 0 0 3 3 3 0 Extracellular matrix protein 1 (ECM1) F-box_4 PF15966.5 EFI26808.1 - 0.82 9.6 9.9 2.3 8.1 0.1 3.2 3 0 0 3 3 3 0 F-box Spy1 PF11357.8 EFI26808.1 - 4.2 7.7 4.9 24 5.2 0.1 2.3 2 0 0 2 2 2 0 Cell cycle regulatory protein p450 PF00067.22 EFI26809.1 - 1.5e-65 221.8 0.0 2.1e-48 165.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TPMT PF05724.11 EFI26810.1 - 1.1e-32 113.4 0.0 1.4e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EFI26810.1 - 1.4e-10 41.7 0.0 2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EFI26810.1 - 7e-09 36.2 0.0 1e-08 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EFI26810.1 - 1.7e-08 34.4 0.0 2.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EFI26810.1 - 8.3e-08 32.9 0.0 1.6e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EFI26810.1 - 4.1e-06 26.7 0.0 5.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EFI26810.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB F-box-like PF12937.7 EFI26811.1 - 0.018 14.9 1.1 0.04 13.8 0.2 2.2 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 EFI26811.1 - 0.045 13.6 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 F-box F-box PF00646.33 EFI26811.1 - 0.054 13.4 0.1 0.054 13.4 0.1 2.5 4 0 0 4 4 4 0 F-box domain KIND PF16474.5 EFI26812.1 - 0.0088 16.0 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Kinase non-catalytic C-lobe domain Epimerase PF01370.21 EFI26813.1 - 1.3e-33 116.4 0.0 2.1e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EFI26813.1 - 2.9e-14 53.2 0.0 7.5e-14 51.9 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glycos_transf_2 PF00535.26 EFI26813.1 - 1.1e-13 51.3 0.1 2.5e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 3Beta_HSD PF01073.19 EFI26813.1 - 2.5e-08 33.3 0.0 3.8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EFI26813.1 - 7.2e-08 31.9 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EFI26813.1 - 4.2e-07 30.0 0.0 7.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_tranf_2_3 PF13641.6 EFI26813.1 - 3.5e-05 23.8 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Polysacc_synt_2 PF02719.15 EFI26813.1 - 0.00011 21.5 0.0 0.00025 20.3 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Glyco_tranf_2_2 PF10111.9 EFI26813.1 - 0.00042 19.9 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RmlD_sub_bind PF04321.17 EFI26813.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain HLH PF00010.26 EFI26814.1 - 9.3e-19 67.1 0.3 3.9e-18 65.1 0.0 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2729 PF10870.8 EFI26814.1 - 0.39 10.6 0.4 0.71 9.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) DEAD PF00270.29 EFI26818.1 - 6.5e-16 58.6 0.0 1.8e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EFI26818.1 - 4.2e-10 40.2 1.2 1.3e-09 38.6 0.1 2.4 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 EFI26818.1 - 1.9e-07 31.4 0.0 0.00062 20.1 0.0 3.3 2 1 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 EFI26818.1 - 8.5e-06 25.5 0.4 0.00016 21.4 0.4 2.5 1 1 0 1 1 1 1 RQC domain ResIII PF04851.15 EFI26818.1 - 0.00061 19.8 0.0 0.0021 18.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HMG14_17 PF01101.18 EFI26818.1 - 5.9 7.9 11.4 2.7 9.0 6.3 2.8 2 0 0 2 2 2 0 HMG14 and HMG17 YabA PF06156.13 EFI26818.1 - 9.2 7.0 8.1 3.9 8.2 4.5 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Phage_TAC_12 PF12363.8 EFI26823.1 - 0.062 13.7 0.0 0.085 13.3 0.0 1.1 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC H_lectin PF09458.10 EFI26824.1 - 1.7e-37 127.4 2.6 2.7e-15 56.3 0.1 3.9 4 0 0 4 4 4 3 H-type lectin domain TGFb_propeptide PF00688.18 EFI26825.1 - 0.24 11.1 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 TGF-beta propeptide PRIMA1 PF16101.5 EFI26829.1 - 0.13 12.3 0.3 0.26 11.3 0.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PHD PF00628.29 EFI26830.1 - 5.3e-07 29.4 10.3 1.1e-06 28.5 10.3 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EFI26830.1 - 1.3 8.6 7.6 2.7 7.6 7.6 1.5 1 0 0 1 1 1 0 PHD-finger CFEM PF05730.11 EFI26831.1 - 0.00014 21.9 6.8 0.00019 21.4 6.8 1.2 1 0 0 1 1 1 1 CFEM domain CEND1 PF15677.5 EFI26831.1 - 0.0012 19.4 0.2 0.0012 19.4 0.2 1.2 1 0 0 1 1 1 1 Cell cycle exit and neuronal differentiation protein 1 PRIMA1 PF16101.5 EFI26831.1 - 1.1 9.4 13.3 0.065 13.3 7.4 1.9 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 zf-MYND PF01753.18 EFI26834.1 - 9.7e-09 35.2 10.0 1.9e-08 34.3 10.0 1.4 1 0 0 1 1 1 1 MYND finger ArAE_2 PF10334.9 EFI26834.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Hydrophobin PF01185.18 EFI26839.1 - 4.3e-08 33.7 0.2 6.3e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Fungal hydrophobin DUF1996 PF09362.10 EFI26842.1 - 5.4e-65 219.7 0.0 6.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ATP_sub_h PF10775.9 EFI26842.1 - 0.2 11.7 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase complex subunit h DUF1996 PF09362.10 EFI26843.1 - 0.00028 21.0 0.1 0.00036 20.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NAD_binding_4 PF07993.12 EFI26844.1 - 1.6e-27 96.3 0.0 2.9e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein ABA_GPCR PF12430.8 EFI26844.1 - 8.5e-15 55.0 2.2 1.9e-14 53.8 2.2 1.6 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor Epimerase PF01370.21 EFI26844.1 - 2.9e-06 26.9 0.0 6.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EFI26844.1 - 0.021 13.8 0.0 0.13 11.2 0.0 1.9 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_C33 PF05412.12 EFI26844.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Glyco_trans_1_3 PF13528.6 EFI26844.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 RmlD_sub_bind PF04321.17 EFI26844.1 - 0.076 12.1 0.1 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain F-protein PF00469.20 EFI26844.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Pkinase_fungal PF17667.1 EFI26846.1 - 6.9e-19 67.9 0.0 2.9e-17 62.6 0.0 2.3 1 1 1 2 2 2 2 Fungal protein kinase ACOX PF01756.19 EFI26847.1 - 3.6e-41 140.7 0.0 7.1e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EFI26847.1 - 1.5e-19 70.8 0.1 3.3e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EFI26847.1 - 2.9e-07 30.6 0.1 1.1e-06 28.8 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain APH PF01636.23 EFI26848.1 - 5.5e-11 42.8 0.0 1.3e-09 38.3 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EFI26848.1 - 0.041 13.5 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Apt1 PF10351.9 EFI26848.1 - 2.5 6.8 7.1 5.2 5.8 7.1 1.5 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-box PF00646.33 EFI26849.1 - 1.2e-06 28.2 1.2 3.7e-06 26.7 1.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EFI26849.1 - 0.00011 22.1 0.3 0.00035 20.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 EFI26849.1 - 0.0056 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain TRPM_tetra PF16519.5 EFI26849.1 - 0.086 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Tetramerisation domain of TRPM MFS_1 PF07690.16 EFI26850.1 - 3.2e-20 72.4 11.9 6e-20 71.5 11.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Zea_mays_MuDR PF05928.11 EFI26852.1 - 0.076 12.6 0.0 12 5.5 0.0 2.3 2 1 0 2 2 2 0 Zea mays MURB-like protein (MuDR) DUF1952 PF09189.10 EFI26854.1 - 0.076 12.9 2.0 0.11 12.3 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1952) PALP PF00291.25 EFI26854.1 - 0.16 11.4 0.5 0.17 11.2 0.5 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_hydro_62 PF03664.13 EFI26857.1 - 1.7e-55 188.3 1.6 2.2e-55 187.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 EFI26857.1 - 2.8e-08 33.6 4.0 1.3e-07 31.4 4.0 2.2 1 1 0 1 1 1 1 Fungal cellulose binding domain Peptidase_M43 PF05572.13 EFI26865.1 - 1.7e-18 67.0 0.0 2.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EFI26865.1 - 2.6e-06 27.7 0.1 6.5e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EFI26865.1 - 0.00083 19.1 0.1 0.002 17.8 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EFI26865.1 - 0.00084 19.9 0.4 0.012 16.2 0.4 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EFI26865.1 - 0.028 14.3 0.4 0.057 13.3 0.4 1.6 1 1 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 EFI26865.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EFI26865.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.9 EFI26865.1 - 0.15 11.0 1.4 0.23 10.3 1.4 1.2 1 0 0 1 1 1 0 Peptidase M66 RNase_P_Rpp14 PF01900.19 EFI26867.1 - 0.098 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Rpp14/Pop5 family zf-C3H1 PF10650.9 EFI26868.1 - 0.23 11.2 0.2 0.41 10.4 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain TPR_2 PF07719.17 EFI26870.1 - 7.5e-11 41.3 1.3 0.033 14.3 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EFI26870.1 - 1.6e-10 40.3 0.2 0.037 13.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EFI26870.1 - 7.6e-08 31.9 0.7 0.04 13.6 0.1 3.9 4 1 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 EFI26870.1 - 1.8e-06 28.5 1.9 0.0053 17.4 0.1 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EFI26870.1 - 2.6e-06 27.6 6.3 0.01 16.1 0.0 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EFI26870.1 - 6.8e-06 25.9 0.0 0.87 10.0 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EFI26870.1 - 3.4e-05 23.5 9.8 0.47 10.4 0.0 4.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EFI26870.1 - 3.8e-05 24.2 9.7 0.29 12.0 0.1 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EFI26870.1 - 4.3e-05 23.3 6.5 1.5 9.0 0.2 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EFI26870.1 - 0.00026 21.5 5.5 0.0066 16.9 0.3 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EFI26870.1 - 0.0015 18.7 0.0 1.2 9.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 EFI26870.1 - 0.0079 16.8 0.1 2.2 9.1 0.0 3.3 4 0 0 4 4 3 1 Sel1 repeat MIT PF04212.18 EFI26870.1 - 0.0082 16.2 0.0 5.6 7.1 0.0 2.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EFI26870.1 - 0.0097 16.5 0.6 26 5.7 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 EFI26870.1 - 0.054 14.2 2.3 30 5.7 0.5 3.6 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat SHNi-TPR PF10516.9 EFI26870.1 - 0.072 12.5 4.3 21 4.7 0.0 3.9 4 0 0 4 4 4 0 SHNi-TPR Exonuc_VII_S PF02609.16 EFI26870.1 - 0.074 13.1 6.9 16 5.7 0.0 3.8 4 0 0 4 4 4 0 Exonuclease VII small subunit Enolase_C PF00113.22 EFI26870.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain UCH PF00443.29 EFI26871.1 - 3.5e-38 131.6 0.0 5.4e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EFI26871.1 - 1e-10 41.8 0.0 2.5e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EFI26871.1 - 7.3e-05 22.4 0.0 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Pkinase_fungal PF17667.1 EFI26873.1 - 9.2e-12 44.4 0.0 3.1e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 EFI26874.1 - 1.4e-13 50.5 0.0 1.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EFI26874.1 - 0.00047 20.1 0.0 0.00068 19.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3552 PF12072.8 EFI26874.1 - 3.5 7.0 9.5 4.7 6.6 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) CAP_N PF01213.19 EFI26874.1 - 6.9 6.1 5.8 0.74 9.2 1.5 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Acetyltransf_8 PF13523.6 EFI26875.1 - 1.1e-39 135.4 0.3 1.9e-39 134.6 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EFI26875.1 - 1.9e-06 28.6 0.2 4e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2530 PF10745.9 EFI26877.1 - 0.11 12.8 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) Helitron_like_N PF14214.6 EFI26879.1 - 2.2e-32 112.9 0.0 3.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF202 PF02656.15 EFI26882.1 - 0.00033 21.0 2.7 0.00033 21.0 2.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Trp_oprn_chp PF09534.10 EFI26882.1 - 0.025 14.4 0.2 0.033 14.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) zf-CCHC PF00098.23 EFI26884.1 - 7.9e-10 38.4 5.9 0.00049 20.1 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle Asp_protease_2 PF13650.6 EFI26884.1 - 4.4e-07 30.5 0.0 0.02 15.6 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease zf-CCCH_6 PF18585.1 EFI26884.1 - 2.7e-05 24.0 1.1 0.34 10.8 0.1 2.8 2 0 0 2 2 2 2 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 RVP_2 PF08284.11 EFI26884.1 - 3.5e-05 23.6 0.0 0.0034 17.1 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 EFI26884.1 - 4.5e-05 23.9 0.0 0.48 11.0 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease zf-CCHC_6 PF15288.6 EFI26884.1 - 0.0004 20.1 7.2 0.22 11.4 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle PilJ_C PF18223.1 EFI26884.1 - 0.056 14.0 1.7 7.4 7.2 0.2 2.7 2 0 0 2 2 2 0 Pili PilJ C-terminal domain DZR PF12773.7 EFI26884.1 - 0.19 11.7 3.1 13 5.9 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-CCHC_4 PF14392.6 EFI26884.1 - 0.37 10.6 6.0 7 6.5 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle Cnn_1N PF07989.11 EFI26886.1 - 1.7e-23 82.6 12.0 1.7e-23 82.6 12.0 13.9 5 2 8 13 13 13 2 Centrosomin N-terminal motif 1 DUF812 PF05667.11 EFI26886.1 - 0.0002 20.4 27.7 0.0002 20.4 27.7 5.5 1 1 3 5 5 5 1 Protein of unknown function (DUF812) HIP1_clath_bdg PF16515.5 EFI26886.1 - 0.0017 18.9 9.3 0.0017 18.9 9.3 13.7 3 2 13 16 16 16 2 Clathrin-binding domain of Huntingtin-interacting protein 1 bZIP_1 PF00170.21 EFI26886.1 - 0.0034 17.4 1.2 0.0034 17.4 1.2 14.7 9 6 5 15 15 15 4 bZIP transcription factor Mto2_bdg PF12808.7 EFI26886.1 - 0.014 15.7 10.8 0.014 15.7 10.8 13.8 13 4 1 15 15 15 0 Micro-tubular organiser Mto1 C-term Mto2-binding region MICSWaP PF17018.5 EFI26886.1 - 0.79 9.2 4.0 0.63 9.6 0.9 2.6 2 0 0 2 2 2 0 Spore wall protein GhoS PF11080.8 EFI26886.1 - 2.4 8.2 5.4 23 5.1 0.0 4.4 4 0 0 4 4 4 0 Endoribonuclease GhoS DUF4407 PF14362.6 EFI26886.1 - 4.2 6.6 122.5 3.6 6.9 3.8 7.9 2 2 4 6 6 6 0 Domain of unknown function (DUF4407) Flavodoxin_1 PF00258.25 EFI26889.1 - 2.7e-30 105.5 0.0 4.1e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EFI26889.1 - 2.6e-21 76.2 0.2 3.8e-16 59.3 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 EFI26889.1 - 5.6e-06 27.0 0.0 2.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EFI26889.1 - 0.0037 17.5 0.0 0.0099 16.1 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin domain DUF4470 PF14737.6 EFI26890.1 - 3.2e-09 36.8 0.0 5.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EFI26890.1 - 2.2e-05 24.0 0.1 4.1e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EFI26890.1 - 0.061 13.5 0.6 0.51 10.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SUI1 PF01253.22 EFI26892.1 - 1.4e-16 60.8 0.0 3.1e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EFI26892.1 - 1.1e-12 48.5 0.0 3.3e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EFI26892.1 - 0.00089 19.2 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 EFI26892.1 - 0.013 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 SWIB/MDM2 domain Usp PF00582.26 EFI26892.1 - 0.071 13.6 2.7 11 6.5 0.9 2.4 2 0 0 2 2 2 0 Universal stress protein family SPX PF03105.19 EFI26893.1 - 0.93 9.3 5.2 1.3 8.9 5.2 1.1 1 0 0 1 1 1 0 SPX domain PAP_assoc PF03828.19 EFI26896.1 - 7.1e-13 48.6 0.2 1.7e-12 47.4 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EFI26896.1 - 1.9e-05 24.9 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EFI26896.1 - 0.0078 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase zf-H2C2_2 PF13465.6 EFI26898.1 - 4.2e-10 39.6 7.2 1.1e-07 31.9 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EFI26898.1 - 1.1e-06 28.7 8.3 0.00036 20.8 0.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EFI26898.1 - 7.6e-06 26.3 8.0 0.018 15.9 1.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EFI26898.1 - 0.0025 18.4 3.7 0.95 10.1 0.3 2.2 2 0 0 2 2 2 2 FOXP coiled-coil domain IBR PF01485.21 EFI26898.1 - 0.017 15.3 2.2 0.025 14.8 2.2 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.12 EFI26898.1 - 0.018 15.4 2.1 0.018 15.4 2.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 EFI26898.1 - 0.047 13.8 1.6 0.19 11.8 1.6 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger Gp_dh_N PF00044.24 EFI26902.1 - 3.4e-05 24.1 0.0 5.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pkinase PF00069.25 EFI26903.1 - 1e-35 123.4 0.0 2.5e-35 122.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI26903.1 - 2.7e-26 92.4 0.0 5.1e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EFI26903.1 - 8.4e-06 25.3 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 EFI26903.1 - 1e-05 25.8 0.1 3e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Seadorna_VP7 PF07387.11 EFI26903.1 - 0.2 10.7 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Asp_protease_2 PF13650.6 EFI26905.1 - 0.058 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EFI26905.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SAP PF02037.27 EFI26909.1 - 9.6e-06 25.2 0.3 1.7e-05 24.5 0.3 1.4 1 0 0 1 1 1 1 SAP domain Rft-1 PF04506.13 EFI26910.1 - 1.2e-127 426.8 8.0 1.4e-127 426.6 8.0 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 EFI26910.1 - 0.00018 21.0 1.8 0.00018 21.0 1.8 3.1 3 2 0 3 3 3 1 Polysaccharide biosynthesis protein JAKMIP_CC3 PF16034.5 EFI26913.1 - 0.039 13.9 4.5 0.074 13.0 4.5 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain PCRF PF03462.18 EFI26913.1 - 0.12 12.2 1.5 0.21 11.4 1.5 1.3 1 0 0 1 1 1 0 PCRF domain Exonuc_VII_L PF02601.15 EFI26913.1 - 0.21 11.1 3.0 0.33 10.5 3.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lebercilin PF15619.6 EFI26913.1 - 0.25 11.0 9.9 0.98 9.1 9.7 1.8 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 EFI26913.1 - 0.32 10.8 4.2 0.67 9.8 4.2 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH MMR_HSR1 PF01926.23 EFI26917.1 - 0.0055 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EFI26917.1 - 0.0067 15.8 3.5 0.065 12.6 0.0 2.6 1 1 2 3 3 3 1 AIG1 family Adeno_hexon_C PF03678.14 EFI26917.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, C-terminal domain HSP70 PF00012.20 EFI26918.1 - 0.0028 15.9 0.0 1.4 7.0 0.0 2.4 2 1 0 2 2 2 2 Hsp70 protein Baculo_DNA_bind PF04786.12 EFI26918.1 - 0.0054 16.1 0.1 0.0079 15.6 0.1 1.2 1 0 0 1 1 1 1 ssDNA binding protein Peptidase_M22 PF00814.25 EFI26918.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Sec66 PF09802.9 EFI26918.1 - 0.092 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DUF4811 PF16069.5 EFI26919.1 - 0.22 11.4 1.1 0.41 10.5 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) Rap_GAP PF02145.15 EFI26920.1 - 5.5e-42 143.4 0.0 9.2e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EFI26920.1 - 8.5e-36 123.8 2.4 2.7e-33 115.6 0.3 2.3 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 EFI26920.1 - 0.013 14.4 0.0 3.4 6.5 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3384) Ank_2 PF12796.7 EFI26923.1 - 3.4e-34 117.3 0.0 2.4e-16 60.1 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EFI26923.1 - 1.1e-28 98.9 1.4 1.1e-08 35.2 0.2 5.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EFI26923.1 - 1.3e-23 83.0 0.0 1.6e-06 28.5 0.0 5.1 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EFI26923.1 - 4.7e-23 80.6 1.7 0.0007 19.9 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 EFI26923.1 - 8.1e-15 53.5 0.1 0.98 10.2 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Got1 PF04178.12 EFI26924.1 - 5.7e-15 55.7 0.9 4.6e-14 52.8 0.9 1.9 1 1 0 1 1 1 1 Got1/Sft2-like family TraE PF05309.11 EFI26925.1 - 0.067 12.6 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 TraE protein MCM_bind PF09739.9 EFI26925.1 - 0.93 7.9 6.4 0.31 9.4 3.3 1.7 1 1 1 2 2 2 0 Mini-chromosome maintenance replisome factor Dicty_REP PF05086.12 EFI26925.1 - 1.2 7.0 4.8 0.11 10.5 0.3 1.4 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF4551 PF15087.6 EFI26925.1 - 4 6.2 11.1 4.4 6.0 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CxC4 PF18717.1 EFI26926.1 - 1.9e-45 153.9 0.0 3.8e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EFI26927.1 - 6.7e-05 22.6 0.8 8.3e-05 22.3 0.8 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CNOT11 PF10155.9 EFI26928.1 - 1.4e-26 93.1 0.0 1.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 PQQ_2 PF13360.6 EFI26931.1 - 2.1e-16 60.3 5.4 1.3e-07 31.5 0.1 3.4 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 EFI26931.1 - 1.2e-08 34.5 6.2 0.00039 20.2 0.0 5.1 6 0 0 6 6 6 2 PQQ enzyme repeat EMC1_C PF07774.13 EFI26932.1 - 1.8e-70 236.9 0.0 2.4e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal COG6 PF06419.11 EFI26934.1 - 3.4e-158 527.7 0.9 3.4e-158 527.7 0.9 1.6 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Laminin_I PF06008.14 EFI26934.1 - 0.018 14.8 4.9 0.037 13.7 4.9 1.4 1 0 0 1 1 1 0 Laminin Domain I OmpH PF03938.14 EFI26934.1 - 0.044 14.1 6.5 0.13 12.7 6.5 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 EFI26934.1 - 0.065 12.8 1.4 0.13 11.8 1.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EFI26934.1 - 0.084 12.9 3.7 0.24 11.4 3.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EFI26934.1 - 0.1 13.1 0.9 1.2 9.7 0.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec34 PF04136.15 EFI26934.1 - 0.14 12.1 3.7 0.47 10.3 3.7 2.0 1 0 0 1 1 1 0 Sec34-like family COG2 PF06148.11 EFI26934.1 - 0.25 11.4 3.0 0.69 10.0 3.0 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FlgN PF05130.12 EFI26934.1 - 0.35 11.4 6.9 4.8 7.7 4.9 2.8 1 1 1 2 2 2 0 FlgN protein TBK1_CCD1 PF18394.1 EFI26934.1 - 0.55 9.7 6.0 1.1 8.7 0.7 2.3 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 CCDC53 PF10152.9 EFI26934.1 - 0.59 10.5 4.3 2.1 8.7 0.8 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex GEMIN8 PF15348.6 EFI26934.1 - 1.5 9.0 7.2 1.3 9.3 0.8 3.0 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 TFIIA PF03153.13 EFI26934.1 - 1.7 8.5 10.0 0.54 10.2 2.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.11 EFI26934.1 - 4.4 6.9 30.5 0.87 9.2 2.7 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Peptidase_S9 PF00326.21 EFI26935.1 - 1e-26 93.8 0.0 6.4e-24 84.6 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EFI26935.1 - 8.8e-08 31.7 0.1 2.3e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EFI26935.1 - 3.7e-07 30.1 0.2 0.00087 19.0 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EFI26935.1 - 0.00088 19.2 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EFI26935.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EFI26935.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family STE3 PF02076.15 EFI26937.1 - 1.7e-96 322.9 18.0 2.2e-96 322.5 18.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.15 EFI26938.1 - 2.3e-78 263.4 10.9 2.7e-78 263.1 10.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor PTCRA PF15028.6 EFI26938.1 - 0.021 14.5 0.1 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 Pre-T-cell antigen receptor Pheromone PF08015.11 EFI26940.1 - 7.8e-15 55.7 0.6 8.5e-15 55.6 0.6 1.0 1 0 0 1 1 1 1 Fungal mating-type pheromone MFS_1 PF07690.16 EFI26941.1 - 5.3e-20 71.6 35.1 1.3e-10 40.7 5.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EFI26941.1 - 7e-13 48.2 17.5 9.2e-12 44.6 17.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EFI26942.1 - 7.9e-22 77.7 51.9 7.3e-20 71.2 30.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EFI26942.1 - 1.1e-12 47.5 15.3 3.9e-12 45.8 15.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1708 PF08101.11 EFI26947.1 - 2.9e-17 63.0 0.0 2.6e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 EFI26947.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain KH_4 PF13083.6 EFI26947.1 - 1.3 8.9 2.8 5.1 7.1 2.8 2.1 1 0 0 1 1 1 0 KH domain Peptidase_M43 PF05572.13 EFI26949.1 - 9.7e-19 67.8 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EFI26949.1 - 1.1e-06 29.0 0.0 2.7e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EFI26949.1 - 0.00015 22.3 0.0 0.00025 21.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EFI26949.1 - 0.00024 20.8 0.0 0.00048 19.8 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EFI26949.1 - 0.009 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EFI26949.1 - 0.046 13.6 0.1 0.076 12.9 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 EFI26949.1 - 0.072 12.0 1.0 0.11 11.4 1.0 1.1 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M43 PF05572.13 EFI26950.1 - 4.6e-18 65.6 0.0 7.1e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EFI26950.1 - 3.6e-07 30.5 0.0 5.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EFI26950.1 - 3.1e-05 24.5 0.0 5.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EFI26950.1 - 0.00062 19.5 0.0 0.0011 18.6 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EFI26950.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.3 1 1 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.8 EFI26950.1 - 0.02 14.5 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.6 EFI26950.1 - 0.039 13.8 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EFI26950.1 - 0.17 10.8 1.3 0.26 10.2 1.3 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 EFI26950.1 - 0.27 10.4 0.2 0.53 9.4 0.2 1.4 1 0 0 1 1 1 0 Met-zincin Plavaka PF18759.1 EFI26951.1 - 8.9e-27 94.2 0.1 2.1e-26 92.9 0.0 1.6 2 0 0 2 2 2 1 Plavaka transposase zf-C2H2 PF00096.26 EFI26951.1 - 0.0029 18.0 0.0 0.0029 18.0 0.0 2.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EFI26951.1 - 0.051 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type Tho2 PF11262.8 EFI26951.1 - 0.23 10.6 0.9 0.48 9.6 0.9 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-C2H2_4 PF13894.6 EFI26951.1 - 0.51 11.3 1.8 1.2 10.2 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger ENOD40 PF08247.11 EFI26959.1 - 9.5 6.5 7.0 16 5.7 1.4 2.5 2 0 0 2 2 2 0 ENOD40 protein DNA_pol_B_exo2 PF10108.9 EFI26960.1 - 0.16 11.6 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Thioredoxin_16 PF18569.1 EFI26965.1 - 0.5 10.5 2.3 0.56 10.4 0.7 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Pkinase_fungal PF17667.1 EFI26968.1 - 5.4e-19 68.3 0.0 8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cauli_AT PF03233.13 EFI26968.1 - 0.0076 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Aphid transmission protein CCER1 PF15482.6 EFI26968.1 - 0.23 11.3 0.1 0.23 11.3 0.1 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Peptidase_C14 PF00656.22 EFI26976.1 - 0.0013 18.7 0.0 0.0023 18.0 0.0 1.4 1 0 0 1 1 1 1 Caspase domain MSA-2c PF12238.8 EFI26976.1 - 1.8 8.5 8.2 4 7.4 8.2 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Peptidase_C14 PF00656.22 EFI26977.1 - 1.5e-12 48.0 0.0 7.2e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Caspase domain 120_Rick_ant PF12574.8 EFI26978.1 - 0.14 11.3 0.2 0.4 9.8 0.2 1.6 1 1 0 1 1 1 0 120 KDa Rickettsia surface antigen Gluconate_2-dh3 PF13618.6 EFI26980.1 - 0.085 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 KDZ PF18758.1 EFI26981.1 - 3.8e-47 160.7 1.1 5.7e-47 160.2 1.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI26981.1 - 3.1e-10 40.2 0.2 1.3e-09 38.2 0.2 2.1 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases TED PF08341.11 EFI26981.1 - 0.21 12.0 1.1 0.44 10.9 1.1 1.5 1 0 0 1 1 1 0 Thioester domain Pkinase_fungal PF17667.1 EFI26983.1 - 3e-46 158.0 0.0 9.9e-23 80.6 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EFI26983.1 - 3.6e-06 26.5 0.0 6.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EFI26986.1 - 3.3e-42 144.7 0.0 5.7e-40 137.3 0.0 2.1 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI26986.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Exonuc_X-T_C PF08411.10 EFI26986.1 - 0.13 11.3 0.1 0.26 10.4 0.1 1.4 1 0 0 1 1 1 0 Exonuclease C-terminal Pkinase_fungal PF17667.1 EFI26987.1 - 7.4e-34 117.2 0.0 2.9e-28 98.8 0.0 2.6 1 1 1 2 2 2 2 Fungal protein kinase Pkinase_fungal PF17667.1 EFI26989.1 - 1.1e-43 149.6 0.0 7.9e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EFI26989.1 - 1.5e-07 31.0 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI26989.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI26990.1 - 9.4e-24 83.9 0.1 1.5e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 EFI26991.1 - 1e-33 116.7 0.2 1.4e-31 109.8 0.2 2.9 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI26991.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EFI26992.1 - 5.7e-35 120.9 0.0 7.1e-33 114.0 0.0 2.2 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI26992.1 - 2e-07 30.7 0.0 3.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EFI26993.1 - 2.3e-48 165.0 0.0 4.5e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI26993.1 - 5.3e-06 26.0 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI26993.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MFS_5 PF05631.14 EFI26999.1 - 9.7e-66 222.1 4.1 1.4e-65 221.5 4.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EFI26999.1 - 1.6e-20 73.3 28.6 2.3e-20 72.8 28.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PCMT PF01135.19 EFI27000.1 - 8.8e-74 247.8 0.0 1e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EFI27000.1 - 1.9e-06 27.7 0.0 1.1e-05 25.2 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EFI27000.1 - 6.4e-05 22.9 0.0 8.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EFI27000.1 - 0.00032 20.7 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EFI27000.1 - 0.0007 20.2 0.0 0.0012 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EFI27000.1 - 0.0039 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 EFI27000.1 - 0.0066 17.1 0.0 0.014 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EFI27000.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EFI27000.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 EFI27000.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EFI27000.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pkinase_fungal PF17667.1 EFI27001.1 - 3.6e-42 144.6 0.0 1.4e-40 139.3 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EFI27001.1 - 8.5e-06 25.3 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EFI27002.1 - 8.9e-39 133.4 0.0 9.9e-38 130.0 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EFI27002.1 - 1.7e-06 27.6 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27002.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4267 PF14087.6 EFI27003.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Pkinase_fungal PF17667.1 EFI27005.1 - 1.9e-46 158.7 0.0 3.7e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI27005.1 - 1.2e-05 24.9 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain BUD22 PF09073.10 EFI27005.1 - 0.00013 21.5 0.8 0.00021 20.8 0.8 1.3 1 0 0 1 1 1 1 BUD22 Pkinase_fungal PF17667.1 EFI27006.1 - 4.8e-44 150.8 0.0 1.8e-43 148.9 0.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI27006.1 - 6.8e-08 32.2 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain T_cell_tran_alt PF15128.6 EFI27007.1 - 0.098 12.5 0.3 0.15 11.9 0.3 1.3 1 0 0 1 1 1 0 T-cell leukemia translocation-altered RabGAP-TBC PF00566.18 EFI27009.1 - 0.00039 20.1 0.0 0.00049 19.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.33 EFI27011.1 - 0.00013 21.7 0.9 0.00013 21.7 0.9 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EFI27011.1 - 0.00037 20.3 0.1 0.00081 19.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like Tugs PF17840.1 EFI27011.1 - 0.096 12.9 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Peptidase_S28 PF05577.12 EFI27013.1 - 2.2e-16 59.7 14.5 4.2e-08 32.4 0.0 4.9 3 2 2 5 5 5 4 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EFI27013.1 - 0.00081 18.9 0.2 0.0015 18.1 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Acetyltransf_3 PF13302.7 EFI27016.1 - 2.6e-15 57.3 0.0 7.2e-15 55.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EFI27016.1 - 0.0001 22.2 0.0 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 EFI27016.1 - 0.00011 22.4 0.1 0.13 12.5 0.2 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EFI27016.1 - 0.004 17.5 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EFI27016.1 - 0.022 14.4 0.1 4.8 6.9 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EFI27016.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_C14 PF00656.22 EFI27017.1 - 4.4e-13 49.7 0.0 7.2e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Aminotran_1_2 PF00155.21 EFI27018.1 - 9.8e-11 41.4 0.0 1.7e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DSPc PF00782.20 EFI27019.1 - 4.2e-28 97.8 0.0 6.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EFI27019.1 - 0.00081 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EFI27019.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) KaiB PF07689.12 EFI27021.1 - 0.06 13.1 0.1 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 KaiB domain DUF1331 PF07048.11 EFI27021.1 - 0.16 11.6 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Filament PF00038.21 EFI27024.1 - 0.0002 21.1 2.6 0.0002 21.1 2.6 2.2 1 1 0 2 2 2 1 Intermediate filament protein COG2 PF06148.11 EFI27024.1 - 0.00099 19.2 0.5 0.00099 19.2 0.5 3.0 1 1 2 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 EFI27024.1 - 0.0016 18.5 3.8 0.0016 18.5 3.8 3.7 3 1 1 4 4 2 1 Designed helical repeat protein 10 domain EzrA PF06160.12 EFI27024.1 - 0.0029 15.9 5.3 0.0041 15.4 4.0 1.8 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Spc7 PF08317.11 EFI27024.1 - 0.0048 15.8 2.4 0.0048 15.8 2.4 2.5 2 1 1 3 3 2 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EFI27024.1 - 0.005 16.9 6.3 0.014 15.4 0.4 3.4 1 1 3 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 EFI27024.1 - 0.0075 16.1 1.8 0.0075 16.1 1.8 2.3 2 1 1 3 3 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CHASE3 PF05227.13 EFI27024.1 - 0.019 14.9 1.7 0.019 14.9 1.7 2.1 1 1 1 2 2 2 0 CHASE3 domain DUF1664 PF07889.12 EFI27024.1 - 0.023 14.7 8.4 0.76 9.8 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PilJ PF13675.6 EFI27024.1 - 0.039 14.0 3.5 2.2 8.3 0.5 3.2 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term COG5 PF10392.9 EFI27024.1 - 0.066 13.4 1.5 4.2 7.5 0.0 3.6 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Hemagglutinin PF00509.18 EFI27024.1 - 0.084 11.3 0.5 0.24 9.8 0.2 1.8 1 1 1 2 2 2 0 Haemagglutinin FlaC_arch PF05377.11 EFI27024.1 - 0.097 13.1 5.5 2.2 8.8 0.1 3.8 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 EFI27024.1 - 0.11 12.6 12.0 0.13 12.4 0.6 4.0 3 1 1 4 4 4 0 TolA binding protein trimerisation BLOC1_2 PF10046.9 EFI27024.1 - 0.11 12.8 2.2 16 5.9 0.3 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2730 PF10805.8 EFI27024.1 - 0.12 12.5 3.2 1.1 9.4 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) FH2 PF02181.23 EFI27024.1 - 0.14 11.3 6.3 0.26 10.4 0.9 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Laminin_II PF06009.12 EFI27024.1 - 0.31 11.1 5.3 1.4 8.9 1.2 2.7 1 1 1 2 2 2 0 Laminin Domain II Atg14 PF10186.9 EFI27024.1 - 0.37 9.8 3.9 0.96 8.5 3.8 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EFI27024.1 - 0.37 10.0 4.6 0.15 11.3 1.1 1.9 1 1 1 2 2 2 0 TMPIT-like protein NPV_P10 PF05531.12 EFI27024.1 - 1 9.9 7.8 1.1 9.7 0.2 4.1 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF445 PF04286.12 EFI27024.1 - 1.3 8.8 8.3 4.5 7.0 8.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Fib_alpha PF08702.10 EFI27024.1 - 1.9 8.6 5.3 3 8.0 0.1 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 EFI27024.1 - 2.9 8.2 7.4 6.9 7.0 0.0 3.6 3 0 0 3 3 3 0 Haemolysin XhlA CobN-Mg_chel PF02514.16 EFI27026.1 - 0.52 8.0 3.2 0.73 7.5 3.2 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Seryl_tRNA_N PF02403.22 EFI27028.1 - 0.028 14.6 0.3 0.039 14.2 0.3 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ferric_reduct PF01794.19 EFI27032.1 - 3.1e-23 82.3 5.9 3.9e-23 81.9 3.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EFI27032.1 - 4.2e-09 36.7 0.0 1.4e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EFI27032.1 - 4.8e-09 36.3 0.0 9.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ni_hydr_CYTB PF01292.20 EFI27032.1 - 0.63 9.6 5.5 0.85 9.2 0.3 2.3 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 p450 PF00067.22 EFI27033.1 - 1.6e-31 109.6 0.0 7.7e-11 41.4 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 FAA_hydrolase PF01557.18 EFI27036.1 - 1.2e-05 25.1 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ESR1_C PF12743.7 EFI27037.1 - 3.6 7.4 4.7 4.9 7.0 0.7 2.3 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Pkinase_Tyr PF07714.17 EFI27044.1 - 4.2e-34 118.0 0.0 7.1e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EFI27044.1 - 4.6e-26 91.7 0.0 9.6e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.23 EFI27044.1 - 1.7e-08 34.6 0.0 5.5e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EFI27044.1 - 1.4e-07 31.1 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EFI27044.1 - 6.3e-05 23.1 0.0 0.13 12.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family APH PF01636.23 EFI27044.1 - 0.00026 21.0 0.2 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RsgA_GTPase PF03193.16 EFI27044.1 - 0.00059 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 EFI27044.1 - 0.0036 16.6 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 EFI27044.1 - 0.0073 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 EFI27044.1 - 0.017 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EFI27044.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EFI27044.1 - 0.029 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC1 PF03109.16 EFI27044.1 - 0.032 14.4 0.0 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 ABC1 family AAA_22 PF13401.6 EFI27044.1 - 0.039 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EFI27044.1 - 0.13 12.8 0.4 0.25 11.8 0.1 1.5 2 0 0 2 2 2 0 AAA domain IlvB_leader PF08049.11 EFI27044.1 - 0.17 11.9 0.1 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 IlvB leader peptide Pkinase PF00069.25 EFI27045.1 - 2.4e-23 82.8 0.0 1e-22 80.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27045.1 - 3.6e-20 72.4 0.0 4.7e-19 68.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AIG1 PF04548.16 EFI27045.1 - 7.2e-11 41.8 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EFI27045.1 - 6.5e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EFI27045.1 - 4e-05 23.6 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EFI27045.1 - 0.00076 19.6 0.0 0.4 10.7 0.0 2.3 1 1 1 2 2 2 2 Dynamin family IstB_IS21 PF01695.17 EFI27045.1 - 0.0017 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein IIGP PF05049.13 EFI27045.1 - 0.007 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) GBP PF02263.19 EFI27045.1 - 0.014 14.7 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.27 EFI27045.1 - 0.016 15.7 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 EFI27045.1 - 0.027 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 EFI27045.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EFI27045.1 - 0.1 12.2 0.3 0.55 9.8 0.0 2.3 2 1 0 3 3 3 0 AAA domain Spore_IV_A PF09547.10 EFI27045.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) T2SSE PF00437.20 EFI27045.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 EFI27045.1 - 0.19 11.4 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MAPEG PF01124.18 EFI27052.1 - 9.6e-15 54.6 2.2 1.2e-14 54.3 2.2 1.2 1 0 0 1 1 1 1 MAPEG family NINJA_B PF16136.5 EFI27054.1 - 0.02 15.3 6.0 0.056 13.8 1.5 2.2 2 0 0 2 2 2 0 Putative nuclear localisation signal Methyltransf_16 PF10294.9 EFI27055.1 - 5.1e-09 36.1 0.0 6.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Cytochrom_B561 PF03188.16 EFI27057.1 - 0.013 15.6 2.6 0.3 11.2 0.1 2.5 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 PIG-P PF08510.12 EFI27057.1 - 0.12 12.3 1.3 0.31 11.0 1.0 1.9 1 1 0 1 1 1 0 PIG-P PCI PF01399.27 EFI27059.1 - 4.5e-24 85.0 0.2 8.8e-23 80.8 0.0 3.2 5 0 0 5 5 5 1 PCI domain Rpn3_C PF08375.11 EFI27059.1 - 5.1e-19 68.5 0.2 5.1e-19 68.5 0.2 3.0 3 0 0 3 3 3 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 EFI27059.1 - 0.0022 17.9 0.9 0.041 14.0 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat NOA36 PF06524.12 EFI27060.1 - 5.6e-05 22.6 7.9 9.1e-05 21.9 7.9 1.3 1 0 0 1 1 1 1 NOA36 protein CENP-B_dimeris PF09026.10 EFI27060.1 - 0.032 14.6 6.1 0.084 13.3 6.1 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC27 PF09507.10 EFI27060.1 - 0.36 10.2 7.2 0.43 9.9 7.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Spt5_N PF11942.8 EFI27060.1 - 0.5 11.4 18.9 1.1 10.3 18.9 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal LIM PF00412.22 EFI27061.1 - 1.5e-30 105.2 28.3 1e-14 54.5 3.5 4.2 3 1 0 3 3 3 3 LIM domain CLTH PF10607.9 EFI27062.1 - 9.1e-36 123.0 0.1 1.6e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain CENP-F_leu_zip PF10473.9 EFI27062.1 - 0.021 14.8 0.6 0.057 13.5 0.6 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 EFI27062.1 - 0.048 13.9 1.1 0.12 12.7 1.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.7 EFI27062.1 - 0.051 13.1 0.2 0.098 12.2 0.2 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1911 PF08929.10 EFI27062.1 - 0.12 13.2 0.1 0.26 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Tex_N PF09371.10 EFI27062.1 - 0.47 10.1 3.4 4.9 6.8 0.7 2.4 2 1 0 2 2 2 0 Tex-like protein N-terminal domain ACCA PF03255.14 EFI27062.1 - 1.1 9.1 3.8 5.6 6.8 0.3 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pkinase PF00069.25 EFI27063.1 - 3.9e-50 170.7 0.0 4.5e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27063.1 - 1.6e-25 89.9 0.0 2.1e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EFI27063.1 - 3.8e-06 26.4 0.0 5.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EFI27063.1 - 0.0038 16.6 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EFI27063.1 - 0.0044 15.8 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase HlyIII PF03006.20 EFI27064.1 - 7.9e-63 212.2 19.5 1e-62 211.8 19.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Lig_chan PF00060.26 EFI27064.1 - 0.093 12.6 0.7 0.21 11.4 0.7 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel UNC-93 PF05978.16 EFI27064.1 - 1.9 8.2 9.0 0.17 11.6 1.8 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Leucyl-specific PF14795.6 EFI27066.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.7 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF2975 PF11188.8 EFI27067.1 - 6.8 6.6 9.8 0.26 11.2 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) PX PF00787.24 EFI27068.1 - 8.6e-20 70.8 0.1 2.5e-19 69.3 0.1 1.8 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 EFI27068.1 - 4.5e-13 49.2 0.4 1.3e-12 47.7 0.4 1.7 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.28 EFI27068.1 - 2.8e-07 30.0 0.0 5.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EFI27068.1 - 1.4e-06 28.1 0.1 3.1e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain Mitoc_mL59 PF18126.1 EFI27070.1 - 2.7e-39 134.4 4.3 4.9e-39 133.6 4.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Glyco_hydro_12 PF01670.16 EFI27071.1 - 1.4e-17 64.4 4.9 1.8e-17 64.1 4.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Ripply PF14998.6 EFI27073.1 - 0.12 13.0 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Transcription Regulator Transp_cyt_pur PF02133.15 EFI27075.1 - 8.3e-25 87.4 38.2 2.3e-23 82.7 38.2 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin M20_dimer PF07687.14 EFI27076.1 - 0.023 14.6 0.0 0.13 12.2 0.0 2.1 2 1 0 2 2 2 0 Peptidase dimerisation domain E1-E2_ATPase PF00122.20 EFI27078.1 - 1.3e-48 164.9 0.1 1.3e-48 164.9 0.1 3.2 5 0 0 5 5 5 1 E1-E2 ATPase Hydrolase PF00702.26 EFI27078.1 - 6.9e-16 59.2 5.4 4.5e-15 56.5 5.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EFI27078.1 - 3.6e-13 49.0 0.0 9.3e-13 47.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EFI27078.1 - 0.00091 19.0 0.0 0.0043 16.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EFI27078.1 - 0.043 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Glyco_hydro_61 PF03443.14 EFI27081.1 - 0.00016 21.7 0.0 0.0002 21.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BCDHK_Adom3 PF10436.9 EFI27083.1 - 7.7e-62 207.9 0.3 4.4e-41 140.4 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EFI27083.1 - 3.2e-11 43.7 0.0 6.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EFI27083.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Agglutinin PF07468.11 EFI27088.1 - 0.0027 17.9 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 Agglutinin domain DUF1996 PF09362.10 EFI27094.1 - 0.00023 21.2 0.1 0.00028 21.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 EFI27095.1 - 4.7e-41 141.3 0.2 5.9e-41 141.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HNH_2 PF13391.6 EFI27097.1 - 0.0015 18.6 0.0 0.0032 17.6 0.0 1.7 1 1 0 1 1 1 1 HNH endonuclease ADH_N_2 PF16884.5 EFI27105.1 - 5.9e-23 80.8 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EFI27105.1 - 1.2e-22 80.3 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EFI27105.1 - 2.3e-05 25.5 0.0 4.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EFI27105.1 - 0.024 14.4 0.1 0.29 10.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) VF530 PF09905.9 EFI27106.1 - 0.042 14.0 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA-binding protein VF530 Fungal_trans PF04082.18 EFI27111.1 - 2.5e-23 82.4 0.9 4.2e-23 81.7 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EFI27111.1 - 1.1e-07 31.8 8.9 1.1e-07 31.8 8.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 EFI27111.1 - 1e-05 25.7 2.7 1e-05 25.7 2.7 3.9 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EFI27111.1 - 0.0012 19.1 19.5 0.032 14.7 3.9 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.7 EFI27111.1 - 0.036 14.5 4.2 0.073 13.5 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EFI27111.1 - 0.074 13.9 19.5 0.1 13.5 2.9 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EFI27111.1 - 0.82 9.7 11.8 0.35 10.9 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger F-box PF00646.33 EFI27112.1 - 1.8e-06 27.6 4.1 6e-06 26.0 4.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EFI27112.1 - 2.6e-05 24.0 2.5 5.5e-05 23.0 2.5 1.6 1 0 0 1 1 1 1 F-box-like Cauli_DNA-bind PF03310.13 EFI27113.1 - 0.14 12.3 0.0 0.14 12.2 0.0 1.0 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DUF4246 PF14033.6 EFI27114.1 - 4.5e-148 494.1 0.0 1.8e-124 416.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EFI27114.1 - 0.018 15.4 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase F-box PF00646.33 EFI27115.1 - 4.9e-08 32.6 4.2 6.5e-08 32.3 3.9 1.4 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 EFI27115.1 - 1.8e-05 24.6 2.0 2.5e-05 24.1 2.0 1.3 1 0 0 1 1 1 1 F-box-like Mit_KHE1 PF10173.9 EFI27117.1 - 1.2e-53 182.0 0.0 1.6e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related BCD PF15461.6 EFI27117.1 - 0.2 11.1 0.1 0.28 10.6 0.1 1.1 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Peptidase_M43 PF05572.13 EFI27118.1 - 9.9e-20 71.0 0.0 2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EFI27118.1 - 1.6e-05 25.1 0.1 3.8e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EFI27118.1 - 0.0015 18.2 0.1 0.0025 17.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EFI27118.1 - 0.0024 18.4 0.2 0.005 17.3 0.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EFI27118.1 - 0.069 13.0 0.7 0.17 11.7 0.4 1.5 1 1 0 1 1 1 0 Matrixin Med13_C PF06333.12 EFI27118.1 - 0.18 11.0 4.1 0.6 9.3 2.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Peptidase_M57 PF12388.8 EFI27118.1 - 0.95 9.0 3.9 0.93 9.1 2.5 2.0 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase TPR_10 PF13374.6 EFI27119.1 - 9.2e-62 203.4 12.7 3e-05 23.7 0.0 14.3 13 2 1 14 14 14 13 Tetratricopeptide repeat CHAT PF12770.7 EFI27119.1 - 1.6e-26 93.4 0.0 2.9e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EFI27119.1 - 6e-24 84.1 14.4 0.017 15.4 0.1 13.8 7 3 7 14 14 14 6 Tetratricopeptide repeat TPR_17 PF13431.6 EFI27119.1 - 4.2e-11 42.4 6.4 14 6.3 0.0 10.7 12 1 1 13 13 13 2 Tetratricopeptide repeat TPR_1 PF00515.28 EFI27119.1 - 0.037 13.9 9.9 2.6 8.0 0.0 8.4 11 0 0 11 11 11 0 Tetratricopeptide repeat Peptidase_C25 PF01364.18 EFI27119.1 - 0.047 12.9 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 TPR_2 PF07719.17 EFI27119.1 - 0.051 13.7 1.3 4.9 7.5 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EFI27119.1 - 0.064 13.5 0.7 35 5.0 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Flavoprotein PF02441.19 EFI27120.1 - 6.7e-52 175.4 0.0 8.3e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein PBP_N PF17093.5 EFI27120.1 - 0.23 11.7 2.6 0.36 11.1 2.6 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DUF4246 PF14033.6 EFI27122.1 - 2.9e-172 573.8 0.0 1.4e-164 548.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EFI27122.1 - 0.015 15.7 0.0 0.037 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ATP-grasp_3 PF02655.14 EFI27122.1 - 0.14 12.2 0.0 3.6 7.6 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain F-box-like PF12937.7 EFI27124.1 - 9.6e-06 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like Cep57_CLD_2 PF14197.6 EFI27124.1 - 0.019 15.0 0.6 0.028 14.5 0.6 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 F-box PF00646.33 EFI27124.1 - 0.066 13.1 0.1 0.28 11.1 0.1 1.9 1 1 0 1 1 1 0 F-box domain Med10 PF09748.9 EFI27124.1 - 0.1 12.5 0.2 0.24 11.4 0.2 1.5 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex PGAP1 PF07819.13 EFI27126.1 - 0.0012 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 EFI27126.1 - 0.0042 16.3 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EFI27126.1 - 0.0081 16.8 0.2 0.013 16.1 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EFI27126.1 - 0.015 14.6 0.2 0.026 13.8 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EFI27126.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Steroid_dh PF02544.16 EFI27128.1 - 3.6e-29 101.7 5.3 3.9e-10 39.9 0.4 3.5 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EFI27128.1 - 1.8e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TPR_10 PF13374.6 EFI27129.1 - 7.2e-70 229.2 12.3 2.9e-05 23.8 0.0 15.7 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_12 PF13424.6 EFI27129.1 - 7.3e-32 109.5 14.4 2.4e-05 24.5 0.3 14.5 10 5 5 15 15 14 8 Tetratricopeptide repeat CHAT PF12770.7 EFI27129.1 - 1.2e-22 80.7 0.0 2.6e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.6 EFI27129.1 - 4e-08 33.1 0.5 19 5.9 0.0 9.3 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 EFI27129.1 - 3.8e-07 29.8 5.3 2.5 8.6 0.0 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 EFI27129.1 - 2.6e-05 23.8 19.5 1.8 8.5 0.2 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EFI27129.1 - 0.002 18.8 10.1 13 6.5 0.1 7.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EFI27129.1 - 0.0036 16.9 2.8 4.6 7.0 0.0 6.2 7 0 0 7 7 7 1 TPR repeat TPR_2 PF07719.17 EFI27129.1 - 0.0065 16.5 14.0 11 6.5 0.2 8.6 8 0 0 8 8 8 1 Tetratricopeptide repeat 7tm_6 PF02949.20 EFI27129.1 - 0.018 14.2 1.5 22 4.0 0.0 4.9 5 1 0 5 5 5 0 7tm Odorant receptor RPN6_N PF18055.1 EFI27129.1 - 0.071 13.5 0.1 1.3e+02 2.9 0.0 5.1 5 1 0 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF4404 PF14357.6 EFI27129.1 - 2.7 8.7 25.3 13 6.5 0.0 8.4 8 2 3 11 11 10 0 Domain of unknown function (DUF4404) p450 PF00067.22 EFI27130.1 - 3.7e-46 157.9 0.0 1.6e-45 155.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EFI27131.1 - 2.3e-54 184.9 0.0 1.5e-28 99.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Tudor_4 PF18358.1 EFI27139.1 - 0.2 11.3 2.2 0.45 10.1 2.2 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain Ebp2 PF05890.12 EFI27140.1 - 1.1e-84 284.2 17.9 1.1e-84 284.2 17.9 2.2 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 GMC_oxred_N PF00732.19 EFI27141.1 - 1.3e-67 228.3 0.0 1.8e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EFI27141.1 - 3.4e-31 108.7 0.0 6.6e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EFI27141.1 - 4.5e-06 26.0 0.0 7.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EFI27141.1 - 8.9e-06 25.9 0.0 0.00051 20.2 0.0 2.8 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EFI27141.1 - 0.00013 21.6 0.0 0.0086 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EFI27141.1 - 0.00051 19.4 0.0 0.00084 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EFI27141.1 - 0.0033 16.6 0.0 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EFI27141.1 - 0.0062 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EFI27141.1 - 0.18 10.5 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EFI27141.1 - 0.21 11.6 0.4 1 9.3 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding BTB PF00651.31 EFI27142.1 - 0.00025 21.2 0.1 0.0008 19.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Transposase_21 PF02992.14 EFI27144.1 - 2.3e-24 85.8 0.0 6.2e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.6 EFI27144.1 - 0.17 11.5 0.0 0.75 9.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4218) Prominin PF05478.11 EFI27148.1 - 0.21 9.5 0.4 0.29 9.1 0.4 1.1 1 0 0 1 1 1 0 Prominin CD34_antigen PF06365.12 EFI27150.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family PriCT_1 PF08708.11 EFI27150.1 - 0.035 13.8 2.0 0.26 11.0 0.1 3.0 2 1 1 3 3 3 0 Primase C terminal 1 (PriCT-1) MASE1 PF05231.14 EFI27150.1 - 0.04 13.1 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 MASE1 Abhydrolase_6 PF12697.7 EFI27151.1 - 0.0014 19.3 2.5 0.0014 19.3 2.5 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EFI27151.1 - 0.014 15.0 0.1 0.04 13.6 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 EFI27151.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 EFI27151.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EFI27151.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3605 PF12239.8 EFI27152.1 - 7.4e-31 107.6 0.6 1.3e-21 77.5 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) DUF2540 PF10802.8 EFI27152.1 - 0.0029 17.6 0.1 0.21 11.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2540) HIT PF01230.23 EFI27152.1 - 0.081 13.7 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 HIT domain adh_short PF00106.25 EFI27153.1 - 7.6e-43 146.3 0.9 1.1e-42 145.8 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EFI27153.1 - 6.8e-32 110.9 0.3 8.7e-32 110.5 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EFI27153.1 - 4.5e-08 33.2 1.4 5.4e-07 29.7 1.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EFI27153.1 - 5.9e-05 22.6 0.4 0.00019 21.0 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EFI27153.1 - 0.00084 19.3 0.3 0.0015 18.4 0.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EFI27153.1 - 0.031 13.4 0.8 0.042 12.9 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.18 EFI27153.1 - 0.1 12.9 0.4 3.9 7.8 0.1 2.8 1 1 1 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 EFI27153.1 - 0.12 11.7 0.2 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase MutS_V PF00488.21 EFI27156.1 - 2.4e-47 161.4 0.3 3.4e-47 160.9 0.3 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EFI27156.1 - 1.2e-05 25.6 0.5 1.2e-05 25.6 0.5 2.0 2 1 0 2 2 2 1 MutS domain III RPN1_RPN2_N PF17781.1 EFI27156.1 - 0.089 12.2 0.4 0.22 10.9 0.4 1.6 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Rad17 PF03215.15 EFI27156.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.9 2 1 0 2 2 2 0 Rad17 P-loop domain MutS_III PF05192.18 EFI27157.1 - 2.1e-22 80.3 0.1 2.9e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 MutS domain III SURF2 PF05477.11 EFI27158.1 - 0.057 13.1 1.7 0.078 12.7 1.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) YmgB PF10798.8 EFI27158.1 - 0.1 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR Cwf_Cwc_15 PF04889.12 EFI27158.1 - 2.9 7.6 9.4 3.9 7.1 9.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SET PF00856.28 EFI27159.1 - 2.2e-14 54.2 0.0 8.5e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 SET domain SHOCT PF09851.9 EFI27160.1 - 0.091 12.5 1.9 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Short C-terminal domain zf-C3H1 PF10650.9 EFI27161.1 - 0.012 15.3 6.2 0.016 14.9 1.4 2.6 2 1 0 2 2 2 0 Putative zinc-finger domain RICTOR_N PF14664.6 EFI27163.1 - 2.5e-123 411.8 3.0 4.8e-123 410.8 3.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EFI27163.1 - 6.2e-40 135.2 3.8 2.7e-36 123.5 0.1 5.4 4 1 2 6 6 6 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EFI27163.1 - 4.6e-37 126.7 0.2 2.5e-35 121.1 0.1 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ribosomal_L22 PF00237.19 EFI27163.1 - 1.5e-33 115.1 1.9 1.8e-33 114.8 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e RICTOR_V PF14668.6 EFI27163.1 - 1e-29 102.5 0.1 4.5e-27 94.1 0.0 4.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EFI27163.1 - 7.4e-06 26.0 9.5 1.1e-05 25.4 8.1 2.1 1 1 0 1 1 1 1 Hr1 repeat HEAT_EZ PF13513.6 EFI27163.1 - 0.12 12.9 0.1 2.9 8.5 0.0 3.5 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 EFI27163.1 - 0.3 11.5 4.1 16 6.1 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat Rrp40_N PF18311.1 EFI27164.1 - 5.4e-14 51.9 0.4 9.9e-14 51.0 0.4 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EFI27164.1 - 1.1e-12 48.1 0.0 3.1e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 KH domain DASH_Dad1 PF08649.10 EFI27168.1 - 9.5e-24 83.4 0.6 1.3e-23 82.9 0.6 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EFI27168.1 - 0.01 15.8 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 TubC_N PF18563.1 EFI27169.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 TubC N-terminal docking domain Methyltransf_33 PF10017.9 EFI27170.1 - 3.1e-43 148.1 0.0 7.8e-42 143.5 0.0 2.0 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Aminotran_1_2 PF00155.21 EFI27171.1 - 2.5e-19 69.7 0.0 3.3e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EFI27171.1 - 3.6e-11 42.5 0.0 5.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase F-box PF00646.33 EFI27174.1 - 0.0043 16.9 0.1 0.0097 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF5342 PF17277.2 EFI27174.1 - 0.0046 17.3 0.1 12 6.3 0.0 3.4 3 0 0 3 3 3 2 Family of unknown function (DUF5342) F-box-like PF12937.7 EFI27174.1 - 0.012 15.5 0.7 0.025 14.5 0.7 1.6 1 0 0 1 1 1 0 F-box-like Peptidase_M20 PF01546.28 EFI27177.1 - 3e-28 98.9 0.0 4.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EFI27177.1 - 6.1e-15 55.4 9.9 1.6e-05 25.6 0.2 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat M20_dimer PF07687.14 EFI27177.1 - 4.3e-12 45.9 0.0 8.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EFI27177.1 - 5.7e-05 23.3 0.1 0.38 11.1 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EFI27177.1 - 0.00013 20.8 0.1 0.081 11.6 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ PF01011.21 EFI27177.1 - 0.029 14.3 1.3 0.16 11.9 0.0 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat WD40_like PF17005.5 EFI27177.1 - 0.13 11.6 0.1 2.5 7.3 0.0 2.4 2 1 1 3 3 3 0 WD40-like domain Mon1 PF03164.14 EFI27178.1 - 5e-62 210.3 0.0 1.6e-39 136.1 0.0 2.1 1 1 1 2 2 2 2 Trafficking protein Mon1 IGR PF09597.10 EFI27178.1 - 2.3e-20 72.4 0.2 4.4e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 IGR protein motif F-box-like PF12937.7 EFI27179.1 - 0.079 12.9 0.1 0.079 12.9 0.1 3.6 5 0 0 5 5 5 0 F-box-like F-box PF00646.33 EFI27179.1 - 0.17 11.8 3.6 0.84 9.6 0.1 3.4 3 1 0 3 3 3 0 F-box domain Scm3 PF10384.9 EFI27180.1 - 1.8e-13 50.0 0.2 1.8e-13 50.0 0.2 2.2 3 0 0 3 3 3 1 Centromere protein Scm3 HSP20 PF00011.21 EFI27181.1 - 3.3e-15 56.1 0.2 5.7e-13 48.9 0.2 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EFI27181.1 - 1.3e-11 43.8 0.0 1.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EFI27181.1 - 0.085 13.9 0.0 0.28 12.2 0.0 1.8 1 1 0 1 1 1 0 CS domain GvpH PF05455.11 EFI27181.1 - 0.11 12.5 0.4 0.45 10.6 0.0 1.9 1 1 1 2 2 2 0 GvpH DUF1325 PF07039.11 EFI27182.1 - 2.4e-35 121.5 0.0 3.3e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain RasGEF PF00617.19 EFI27185.1 - 3.1e-56 190.4 1.5 3.7e-56 190.1 0.3 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EFI27185.1 - 3.4e-19 69.0 0.3 1.4e-18 67.1 0.0 2.3 3 0 0 3 3 3 1 RasGEF N-terminal motif HIT PF01230.23 EFI27185.1 - 3.5e-19 69.3 0.1 8.2e-19 68.2 0.1 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EFI27185.1 - 5.5e-12 46.2 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SH3_1 PF00018.28 EFI27185.1 - 9.1e-12 44.4 0.2 2.1e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EFI27185.1 - 1.8e-11 43.5 0.0 4.1e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EFI27185.1 - 7.5e-10 38.5 0.1 1.4e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain CwfJ_C_1 PF04677.15 EFI27185.1 - 1.5e-08 34.5 0.0 3.5e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 She9_MDM33 PF05546.11 EFI27186.1 - 1.2e-74 250.4 10.2 1.2e-74 250.4 10.2 1.4 1 1 0 1 1 1 1 She9 / Mdm33 family DEC-1_N PF04625.13 EFI27186.1 - 0.0034 16.5 3.1 0.019 14.0 0.9 2.1 2 0 0 2 2 2 1 DEC-1 protein, N-terminal region MLANA PF14991.6 EFI27186.1 - 0.031 14.5 0.0 0.031 14.5 0.0 2.8 4 0 0 4 4 4 0 Protein melan-A MbeB_N PF04837.12 EFI27186.1 - 0.54 10.6 4.7 15 6.0 0.3 4.0 3 0 0 3 3 3 0 MbeB-like, N-term conserved region FAD_binding_1 PF00667.20 EFI27187.1 - 1.9e-53 181.3 0.0 1.1e-52 178.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EFI27187.1 - 1.7e-30 106.1 0.4 1.7e-30 106.1 0.4 2.0 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 EFI27187.1 - 3.6e-20 72.6 0.0 1.1e-19 71.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain HVSL PF09749.9 EFI27189.1 - 1.1e-47 162.6 0.3 1.8e-47 161.8 0.3 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 EFI27189.1 - 1.4e-06 28.3 2.6 1.8e-06 27.9 0.9 1.9 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily DUF1045 PF06299.12 EFI27189.1 - 0.018 15.0 0.2 0.058 13.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Cytomega_UL20A PF05984.12 EFI27190.1 - 2.6 8.4 6.3 11 6.4 3.9 2.4 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein DUF563 PF04577.14 EFI27191.1 - 2e-20 73.8 0.1 3.2e-20 73.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Hpt PF01627.23 EFI27193.1 - 1.1e-11 44.8 0.9 1.5e-11 44.3 0.9 1.2 1 0 0 1 1 1 1 Hpt domain CoA_transf_3 PF02515.17 EFI27194.1 - 2.9e-127 424.8 0.0 3.4e-127 424.6 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III DUF1179 PF06678.11 EFI27195.1 - 0.055 13.5 0.1 0.065 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) DUF4436 PF14494.6 EFI27197.1 - 3.5e-09 36.3 0.6 6.3e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4436) OppC_N PF12911.7 EFI27197.1 - 0.066 13.2 0.4 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C T4SS_CagC PF16943.5 EFI27197.1 - 0.14 12.3 0.2 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system SET PF00856.28 EFI27198.1 - 1.3e-08 35.4 0.0 3.7e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EFI27198.1 - 1.8e-08 34.3 14.5 3.8e-08 33.3 14.5 1.6 1 0 0 1 1 1 1 MYND finger CE2_N PF17996.1 EFI27200.1 - 0.092 12.7 0.0 1.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal SQS_PSY PF00494.19 EFI27201.1 - 7.9e-57 192.7 0.0 1e-56 192.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Sugar_tr PF00083.24 EFI27205.1 - 2.1e-51 175.2 10.5 1.3e-26 93.5 0.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EFI27205.1 - 1.9e-12 46.8 15.9 1.8e-07 30.5 3.9 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily COPIIcoated_ERV PF07970.12 EFI27208.1 - 2.9e-81 272.6 0.0 3.7e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EFI27208.1 - 3.6e-26 91.3 0.2 3.6e-26 91.3 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sec1 PF00995.23 EFI27209.1 - 2.5e-125 419.9 0.0 2.9e-125 419.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SWC7 PF17330.2 EFI27209.1 - 0.11 12.6 0.1 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 EF-hand_14 PF17959.1 EFI27209.1 - 0.11 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain adh_short PF00106.25 EFI27210.1 - 5.2e-07 29.3 0.0 3.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EFI27210.1 - 0.0001 21.9 0.0 0.00022 20.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EFI27211.1 - 8.4e-12 44.9 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EFI27211.1 - 3.7e-07 30.2 0.0 5.1e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EFI27211.1 - 0.00017 21.2 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EFI27211.1 - 0.011 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EFI27211.1 - 0.027 13.9 0.0 0.035 13.6 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EFI27211.1 - 0.2 10.8 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EFI27211.1 - 0.22 11.6 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GH131_N PF18271.1 EFI27214.1 - 1.1e-92 310.4 0.0 1.2e-92 310.2 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 EFI27214.1 - 0.24 11.2 1.0 0.44 10.4 1.0 1.5 1 1 0 1 1 1 0 Polysaccharide lyase SLAC1 PF03595.17 EFI27215.1 - 5.7e-41 140.8 39.0 7.2e-41 140.5 39.0 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Es2 PF09751.9 EFI27215.1 - 3.7 7.2 8.2 4.9 6.8 8.2 1.1 1 0 0 1 1 1 0 Nuclear protein Es2 RPAP1_C PF08620.10 EFI27216.1 - 2.3e-19 69.3 0.0 4.8e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EFI27216.1 - 2.5e-09 36.8 1.0 7.4e-09 35.2 0.8 2.0 2 0 0 2 2 2 1 RPAP1-like, N-terminal Peptidase_M16 PF00675.20 EFI27217.1 - 8.9e-54 181.5 0.2 4.9e-53 179.1 0.6 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EFI27217.1 - 5.5e-43 147.1 0.0 6.4e-40 137.1 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain adh_short PF00106.25 EFI27217.1 - 5.8e-27 94.4 0.0 4.8e-25 88.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EFI27217.1 - 2.7e-16 59.8 0.0 2e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EFI27217.1 - 2.3e-08 34.1 0.2 9.4e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EFI27217.1 - 0.091 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PRP1_N PF06424.12 EFI27219.1 - 0.073 13.5 0.6 0.091 13.2 0.6 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF4139 PF13598.6 EFI27220.1 - 1.7e-44 152.1 0.0 1.1e-41 142.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EFI27220.1 - 5.5e-22 78.0 2.6 3e-21 75.7 0.0 2.9 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) CHAD PF05235.14 EFI27220.1 - 0.076 13.0 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 CHAD domain DUF4618 PF15397.6 EFI27220.1 - 0.11 11.9 1.3 0.36 10.2 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Mito_carr PF00153.27 EFI27223.1 - 1.6e-69 229.9 2.6 1.6e-24 85.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 EFI27224.1 - 0.00088 19.4 18.2 0.0016 18.5 18.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EFI27225.1 - 6.5e-13 48.3 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FCH PF00611.23 EFI27226.1 - 8e-14 51.7 0.2 2.8e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 EFI27226.1 - 9.6e-13 47.8 5.9 1.7e-12 47.1 5.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_9 PF14604.6 EFI27226.1 - 2.8e-10 39.9 0.0 5.8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EFI27226.1 - 4.1e-09 35.9 0.0 7.8e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EFI27226.1 - 5.3e-05 22.8 0.0 0.00018 21.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Baculo_PEP_C PF04513.12 EFI27226.1 - 7.7 6.6 6.4 2.5 8.1 0.7 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lar_restr_allev PF14354.6 EFI27228.1 - 0.017 15.5 6.1 0.98 9.8 0.0 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf_C2HC_14 PF18574.1 EFI27228.1 - 0.66 9.8 7.0 0.36 10.6 4.0 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain RIBIOP_C PF04950.12 EFI27230.1 - 9.8e-95 317.3 0.0 9.8e-95 317.3 0.0 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EFI27230.1 - 1e-30 105.6 0.0 4.2e-30 103.7 0.0 2.2 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 EFI27230.1 - 8.8e-06 26.2 0.3 4.8e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EFI27230.1 - 2.4e-05 24.6 0.0 7.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rtf2 PF04641.12 EFI27230.1 - 4.6e-05 22.9 3.8 4.6e-05 22.9 3.8 3.8 4 0 0 4 4 3 1 Rtf2 RING-finger GTP_EFTU PF00009.27 EFI27230.1 - 5.8e-05 22.7 2.0 0.008 15.7 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EFI27230.1 - 0.00055 20.4 0.1 0.0014 19.0 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EFI27230.1 - 0.00082 19.1 0.1 0.0019 17.9 0.1 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EFI27230.1 - 0.0012 19.1 0.0 0.0012 19.1 0.0 2.5 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 EFI27230.1 - 0.0012 19.4 0.0 0.0012 19.4 0.0 2.4 2 0 0 2 2 1 1 ABC transporter MMR_HSR1 PF01926.23 EFI27230.1 - 0.0013 18.8 0.1 0.0048 17.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EFI27230.1 - 0.0032 17.4 0.1 0.0075 16.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EFI27230.1 - 0.0039 16.4 0.0 0.0084 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain MobB PF03205.14 EFI27230.1 - 0.0044 16.9 0.4 0.27 11.1 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 EFI27230.1 - 0.0077 16.6 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EFI27230.1 - 0.0097 16.4 0.1 0.0097 16.4 0.1 3.4 3 0 0 3 3 1 1 AAA domain AAA_28 PF13521.6 EFI27230.1 - 0.014 15.7 0.0 0.014 15.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EFI27230.1 - 0.025 14.1 0.1 0.054 13.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EFI27230.1 - 0.027 14.5 0.0 0.088 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EFI27230.1 - 0.029 14.1 0.1 0.029 14.1 0.1 1.6 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 EFI27230.1 - 0.036 14.0 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 EFI27230.1 - 0.04 13.8 0.5 0.083 12.8 0.5 1.5 1 0 0 1 1 1 0 NTPase Roc PF08477.13 EFI27230.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 EFI27230.1 - 0.042 14.2 0.1 0.099 13.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EFI27230.1 - 0.045 13.8 1.2 0.063 13.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EFI27230.1 - 0.066 12.8 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EFI27230.1 - 0.079 13.4 0.1 0.079 13.4 0.1 3.6 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 EFI27230.1 - 0.095 12.4 0.0 0.095 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EFI27230.1 - 0.14 11.8 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EFI27230.1 - 3.7 8.0 0.0 3.7 8.0 0.0 3.9 3 1 0 3 3 2 0 AAA domain PIF1 PF05970.14 EFI27231.1 - 8e-40 137.1 0.1 3.5e-39 135.0 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EFI27231.1 - 3.6e-18 66.0 0.0 1.2e-17 64.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EFI27231.1 - 1.5e-09 38.3 0.0 3.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EFI27231.1 - 0.0093 16.2 0.0 0.038 14.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EFI27231.1 - 0.011 16.1 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EFI27231.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EFI27231.1 - 0.077 13.5 0.2 0.31 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EFI27231.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EFI27231.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EFI27231.1 - 0.21 11.5 0.0 0.45 10.4 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF2087 PF09860.9 EFI27232.1 - 0.15 12.3 0.0 0.47 10.6 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) CxC6 PF18721.1 EFI27234.1 - 5.7e-23 81.0 7.6 5.7e-23 81.0 7.6 2.7 2 0 0 2 2 2 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EFI27234.1 - 6.9e-23 80.9 2.4 6.9e-23 80.9 2.4 2.2 2 1 1 3 3 3 1 CxC5 like cysteine cluster associated with KDZ transposases SMC_N PF02463.19 EFI27235.1 - 1.2e-68 230.8 1.5 1.6e-68 230.5 1.5 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EFI27235.1 - 1.8e-26 92.7 0.0 5.7e-26 91.1 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EFI27235.1 - 3.6e-14 53.3 6.5 3.3e-07 30.4 0.4 3.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EFI27235.1 - 2.8e-12 47.6 28.4 2.8e-12 47.6 28.4 5.7 3 2 1 4 4 2 2 AAA domain AAA_15 PF13175.6 EFI27235.1 - 9.1e-10 38.8 46.3 8.3e-08 32.3 11.9 5.2 2 2 1 3 3 2 2 AAA ATPase domain DUF3584 PF12128.8 EFI27235.1 - 0.0011 16.6 13.3 0.0011 16.6 13.3 3.7 2 2 1 3 3 2 1 Protein of unknown function (DUF3584) BRE1 PF08647.11 EFI27235.1 - 0.0035 17.4 2.0 0.0035 17.4 2.0 7.4 8 0 0 8 8 8 1 BRE1 E3 ubiquitin ligase FtsK_SpoIIIE PF01580.18 EFI27235.1 - 0.0042 16.5 4.4 0.12 11.7 0.0 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.6 EFI27235.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EFI27235.1 - 0.16 12.4 23.3 1 9.9 0.6 5.3 3 2 0 3 3 3 0 ABC transporter AAA_13 PF13166.6 EFI27235.1 - 0.63 8.6 70.6 0.059 12.0 8.5 6.0 3 2 1 6 6 6 0 AAA domain Baculo_PEP_C PF04513.12 EFI27235.1 - 1.5 8.9 15.0 3.2 7.8 1.5 5.7 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF87 PF01935.17 EFI27235.1 - 3.1 7.8 0.0 3.1 7.8 0.0 6.2 3 2 2 6 6 5 0 Helicase HerA, central domain BLOC1_2 PF10046.9 EFI27235.1 - 5.1 7.5 44.0 0.55 10.6 2.9 7.8 6 3 0 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0184 PF03670.13 EFI27235.1 - 5.6 7.4 10.8 35 4.9 0.2 4.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Sec34 PF04136.15 EFI27235.1 - 8.3 6.3 43.3 0.085 12.7 3.3 6.5 6 1 1 7 7 7 0 Sec34-like family DUF773 PF05600.12 EFI27237.1 - 0.039 12.7 0.3 0.088 11.5 0.2 1.5 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 FliT PF05400.13 EFI27237.1 - 0.25 12.2 2.5 8 7.4 0.2 2.8 2 0 0 2 2 2 0 Flagellar protein FliT SWIRM-assoc_2 PF16496.5 EFI27237.1 - 0.33 9.8 9.6 2.8 6.7 3.3 2.4 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Plavaka PF18759.1 EFI27238.1 - 6.9e-14 51.8 0.0 8.1e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase DCB PF16213.5 EFI27241.1 - 0.044 13.5 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 ubiquitin PF00240.23 EFI27242.1 - 2e-18 65.9 0.8 3.3e-18 65.2 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EFI27242.1 - 9.2e-11 41.4 1.0 1.9e-10 40.4 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 EFI27242.1 - 4.1e-09 36.1 0.6 6.7e-09 35.5 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EFI27242.1 - 2.3e-06 28.1 0.0 4.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 EFI27242.1 - 0.0019 18.1 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EFI27242.1 - 0.026 14.9 0.4 0.045 14.1 0.4 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EFI27242.1 - 0.073 13.1 0.9 0.4 10.7 0.3 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain RPN13_C PF16550.5 EFI27242.1 - 0.093 12.9 2.5 1.8 8.7 0.7 2.6 1 1 1 2 2 2 0 UCH-binding domain Rad60-SLD_2 PF13881.6 EFI27242.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF1464 PF07318.12 EFI27242.1 - 0.16 11.1 0.2 0.24 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Serglycin PF04360.12 EFI27242.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.5 4 0 0 4 4 4 0 Serglycin GerD PF17898.1 EFI27242.1 - 0.67 9.9 8.9 0.086 12.8 4.4 1.8 2 0 0 2 2 2 0 Spore germination GerD central core domain zf-H2C2_5 PF13909.6 EFI27243.1 - 4e-13 48.9 8.1 0.0022 17.7 0.9 5.0 5 0 0 5 5 5 4 C2H2-type zinc-finger domain FOXP-CC PF16159.5 EFI27243.1 - 5.9e-06 26.8 18.8 0.2 12.3 1.2 5.6 1 1 5 6 6 6 2 FOXP coiled-coil domain SpdB PF05122.13 EFI27243.1 - 0.0038 17.3 12.8 12 6.2 0.1 5.9 5 1 1 6 6 6 2 Mobile element transfer protein AMA-1 PF02430.15 EFI27243.1 - 0.0046 16.0 0.3 0.007 15.4 0.2 1.4 1 1 0 1 1 1 1 Apical membrane antigen 1 OrsD PF12013.8 EFI27243.1 - 0.007 16.8 16.1 7.3 7.1 0.1 5.4 3 2 3 6 6 6 3 Orsellinic acid/F9775 biosynthesis cluster protein D DUF1069 PF06370.11 EFI27243.1 - 0.17 11.5 1.4 8.1 6.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1069) zf-C2H2 PF00096.26 EFI27243.1 - 0.81 10.3 0.1 0.81 10.3 0.1 6.0 7 0 0 7 7 7 0 Zinc finger, C2H2 type DUF2719 PF10891.8 EFI27243.1 - 1.2 9.1 4.7 5.5 7.0 0.5 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2719) zf-C4_Topoisom PF01396.19 EFI27243.1 - 7.5 6.4 18.7 30 4.5 0.1 5.5 6 0 0 6 6 6 0 Topoisomerase DNA binding C4 zinc finger Cas_NE0113 PF09623.10 EFI27244.1 - 0.16 11.6 1.3 0.34 10.6 1.3 1.5 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) Pex14_N PF04695.13 EFI27244.1 - 0.51 11.0 9.0 2.2 8.9 2.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 EFI27244.1 - 3.3 7.2 13.0 0.54 9.8 4.4 2.1 2 0 0 2 2 2 0 Spt20 family CDV3 PF15359.6 EFI27244.1 - 3.4 8.2 12.7 1.7 9.1 3.0 2.3 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 zf-H2C2_5 PF13909.6 EFI27246.1 - 1.9e-15 56.3 13.0 0.0028 17.4 0.0 5.3 5 0 0 5 5 5 5 C2H2-type zinc-finger domain FOXP-CC PF16159.5 EFI27246.1 - 2e-07 31.5 12.3 3 8.6 0.1 5.1 1 1 4 5 5 5 5 FOXP coiled-coil domain SpdB PF05122.13 EFI27246.1 - 1.7e-06 28.0 5.1 3.2 8.0 0.1 5.2 5 0 0 5 5 5 3 Mobile element transfer protein zf-C2H2 PF00096.26 EFI27246.1 - 3e-06 27.4 34.8 0.22 12.0 0.4 5.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type OrsD PF12013.8 EFI27246.1 - 0.00078 19.9 11.6 13 6.3 0.0 5.0 4 1 1 5 5 5 2 Orsellinic acid/F9775 biosynthesis cluster protein D Megourin PF17560.2 EFI27246.1 - 0.005 17.0 6.6 23 5.3 0.0 4.8 5 0 0 5 5 5 0 Aphid Megourins DUF4442 PF14539.6 EFI27246.1 - 0.018 15.2 0.0 16 5.6 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4442) FeS PF04060.13 EFI27246.1 - 4.4 7.0 17.1 25 4.6 0.1 5.0 5 0 0 5 5 5 0 Putative Fe-S cluster DUF202 PF02656.15 EFI27248.1 - 1e-15 57.9 4.5 1e-15 57.9 4.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MFS_1 PF07690.16 EFI27249.1 - 4e-49 167.4 45.0 4.1e-44 151.0 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EFI27249.1 - 5e-12 45.4 19.0 2e-08 33.6 5.7 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 EFI27249.1 - 0.00015 20.2 0.4 0.00015 20.2 0.4 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Ion_trans_2 PF07885.16 EFI27251.1 - 1.1e-25 89.4 25.5 3.6e-16 58.9 8.5 3.2 3 0 0 3 3 3 2 Ion channel 7tm_6 PF02949.20 EFI27251.1 - 0.0035 16.5 0.0 0.0087 15.2 0.0 1.6 1 0 0 1 1 1 1 7tm Odorant receptor PCYCGC PF13798.6 EFI27253.1 - 0.2 11.5 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif WD40 PF00400.32 EFI27256.1 - 5.7e-59 194.7 53.3 2.1e-09 37.8 0.1 14.9 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EFI27256.1 - 2e-19 69.7 0.0 0.021 15.1 0.0 10.3 2 1 8 12 12 12 3 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EFI27256.1 - 3.4e-08 33.6 0.1 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 EFI27256.1 - 7.1e-06 25.2 0.3 2.5 7.0 0.0 4.9 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 EFI27256.1 - 0.0028 18.1 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EFI27256.1 - 0.003 17.9 0.0 0.66 10.4 0.1 2.5 2 0 0 2 2 2 1 RNA helicase Helo_like_N PF17111.5 EFI27256.1 - 0.0051 16.2 0.5 0.0081 15.5 0.5 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins PD40 PF07676.12 EFI27256.1 - 0.0077 16.1 0.0 25 5.0 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AAA_33 PF13671.6 EFI27256.1 - 0.011 15.9 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EFI27256.1 - 0.15 12.6 0.4 0.44 11.1 0.4 1.9 1 1 0 1 1 1 0 AAA domain Phage_HK97_TLTM PF06120.11 EFI27256.1 - 0.7 9.0 4.1 1.1 8.4 4.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Ras PF00071.22 EFI27268.1 - 4.4e-21 75.2 0.0 2.1e-20 73.0 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EFI27268.1 - 1.4e-05 25.3 0.1 0.00022 21.4 0.0 2.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EFI27268.1 - 0.0035 16.8 0.1 0.033 13.6 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family TIR_2 PF13676.6 EFI27268.1 - 0.0062 17.1 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain GTP_EFTU PF00009.27 EFI27268.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.22 EFI27269.1 - 3.1e-20 72.4 0.0 3.4e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Ras family DUF3060 PF11259.8 EFI27270.1 - 0.17 11.6 2.1 0.31 10.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) DUF995 PF06191.12 EFI27272.1 - 0.01 15.5 3.8 1 9.0 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF995) MVL PF12151.8 EFI27272.1 - 0.62 10.0 12.9 3.5 7.5 0.2 4.3 4 1 1 5 5 5 0 Mannan-binding protein OCC1 PF15506.6 EFI27275.1 - 0.11 12.6 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 OCC1 family DYW_deaminase PF14432.6 EFI27278.1 - 0.026 14.4 0.3 0.035 14.0 0.3 1.2 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases PNPase PF03726.14 EFI27278.1 - 0.14 12.6 1.2 4.2 7.9 0.2 2.1 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PIF1 PF05970.14 EFI27280.1 - 2.4e-25 89.5 0.0 6.4e-25 88.1 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EFI27280.1 - 3.1e-13 49.9 0.0 2.2e-12 47.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EFI27280.1 - 1.1e-07 32.3 0.0 3.5e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 EFI27280.1 - 0.0033 16.4 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Sin3a_C PF16879.5 EFI27280.1 - 0.042 13.6 0.3 0.098 12.4 0.0 1.7 2 0 0 2 2 2 0 C-terminal domain of Sin3a protein ResIII PF04851.15 EFI27280.1 - 0.078 13.0 0.0 0.45 10.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MeaB PF03308.16 EFI27280.1 - 0.091 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRP36 PF06102.12 EFI27282.1 - 0.06 13.3 0.1 0.094 12.7 0.1 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DUF4267 PF14087.6 EFI27283.1 - 0.14 12.3 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) PRANC PF09372.10 EFI27284.1 - 0.017 15.4 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 PRANC domain F-box-like PF12937.7 EFI27284.1 - 0.32 10.9 2.1 3.5 7.6 0.0 3.1 3 1 0 3 3 3 0 F-box-like Tet_JBP PF12851.7 EFI27290.1 - 9.9e-18 64.6 0.0 1.6e-15 57.3 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.7 EFI27291.1 - 1.5e-12 47.5 0.0 7.3e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily ERM PF00769.19 EFI27292.1 - 0.00089 19.1 1.6 0.0011 18.9 1.6 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Atg14 PF10186.9 EFI27292.1 - 0.0022 17.1 1.1 0.0022 17.1 1.1 1.4 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EFI27292.1 - 0.01 14.7 0.6 0.013 14.4 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein COG2 PF06148.11 EFI27292.1 - 0.017 15.2 1.0 0.024 14.7 1.0 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-C4H2 PF10146.9 EFI27292.1 - 0.019 15.3 0.3 0.026 14.8 0.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein SPAM PF02090.15 EFI27292.1 - 0.032 14.0 2.0 0.046 13.5 2.0 1.1 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF812 PF05667.11 EFI27292.1 - 0.056 12.3 0.6 0.073 11.9 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DLP_helical PF18709.1 EFI27292.1 - 0.057 12.6 3.1 0.077 12.2 3.1 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain SKA2 PF16740.5 EFI27292.1 - 0.07 12.9 0.8 0.16 11.7 0.8 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 MPS2 PF17060.5 EFI27292.1 - 0.1 11.9 0.2 0.12 11.6 0.2 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4200 PF13863.6 EFI27292.1 - 0.12 12.8 5.6 0.16 12.3 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DDE_Tnp_IS66 PF03050.14 EFI27292.1 - 0.19 11.2 1.0 0.36 10.2 1.0 1.4 1 1 0 1 1 1 0 Transposase IS66 family Het-C PF07217.11 EFI27292.1 - 0.23 9.9 0.0 0.28 9.7 0.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Fusion_gly PF00523.18 EFI27292.1 - 0.36 9.0 0.2 0.79 7.9 0.2 1.5 1 1 1 2 2 2 0 Fusion glycoprotein F0 Prefoldin PF02996.17 EFI27292.1 - 0.39 10.6 2.9 0.54 10.2 2.9 1.2 1 0 0 1 1 1 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 EFI27294.1 - 0.1 12.8 17.9 0.24 11.6 10.6 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NlpE PF04170.12 EFI27294.1 - 0.16 13.0 1.4 1.8 9.6 0.1 2.5 1 1 1 2 2 2 0 NlpE N-terminal domain DUF16 PF01519.16 EFI27294.1 - 1.6 9.3 16.9 3.7 8.1 0.3 3.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 EFI27294.1 - 2.5 8.5 22.9 1.4 9.3 1.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF2730 PF10805.8 EFI27294.1 - 3 8.0 8.6 0.55 10.3 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Fib_alpha PF08702.10 EFI27294.1 - 4.8 7.4 16.3 8.6 6.5 7.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 EFI27295.1 - 0.0029 18.1 71.3 0.0056 17.2 18.7 4.4 1 1 2 3 3 3 2 Fez1 Fer2_3 PF13085.6 EFI27297.1 - 0.05 13.6 0.5 0.054 13.5 0.5 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain GAD PF02938.14 EFI27299.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.2 1 0 0 1 1 1 0 GAD domain VPS28 PF03997.12 EFI27300.1 - 7e-71 237.8 0.0 8.1e-71 237.6 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Ank_2 PF12796.7 EFI27301.1 - 2.7e-12 47.1 0.0 0.00045 20.7 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EFI27301.1 - 1.9e-11 44.3 0.2 0.037 14.6 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EFI27301.1 - 6.3e-08 32.3 0.1 0.025 15.1 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EFI27301.1 - 1.1e-07 31.9 0.2 0.12 12.9 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat NACHT PF05729.12 EFI27301.1 - 0.00016 21.6 0.0 0.00045 20.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 EFI27301.1 - 0.00018 21.7 0.7 0.8 10.1 0.1 4.4 4 1 1 5 5 5 1 Ankyrin repeats (many copies) AAA_22 PF13401.6 EFI27301.1 - 0.00066 20.0 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EFI27301.1 - 0.13 11.5 0.1 0.51 9.5 0.1 2.0 1 1 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.6 EFI27301.1 - 0.21 12.0 0.0 0.5 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 EFI27304.1 - 0.00017 21.4 0.4 0.00033 20.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like DUF4471 PF14740.6 EFI27305.1 - 0.01 15.1 0.8 0.015 14.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) TMEM132 PF16070.5 EFI27305.1 - 0.082 12.2 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein family 132 DUF3328 PF11807.8 EFI27305.1 - 0.098 12.4 2.0 0.17 11.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Ntox35 PF15534.6 EFI27305.1 - 0.29 11.6 2.4 0.65 10.5 2.4 1.5 1 0 0 1 1 1 0 Bacterial toxin 35 Ferlin_C PF16165.5 EFI27305.1 - 1.6 8.7 5.2 3.2 7.7 5.2 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF4880 PF16220.5 EFI27306.1 - 0.76 9.7 4.0 1.5 8.8 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) KDZ PF18758.1 EFI27308.1 - 1.9e-38 132.3 1.4 3.3e-38 131.5 1.4 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI27308.1 - 8.2e-24 83.8 1.2 2.9e-21 75.6 0.2 2.8 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EFI27308.1 - 0.04 13.8 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Cortex-I_coil PF09304.10 EFI27309.1 - 0.038 14.2 0.2 0.07 13.3 0.2 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil AAA_2 PF07724.14 EFI27311.1 - 1.3e-47 162.1 0.0 3e-46 157.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EFI27311.1 - 8.9e-34 115.5 4.0 2e-33 114.4 0.2 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EFI27311.1 - 2.6e-21 75.4 3.5 4.4e-21 74.7 0.3 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EFI27311.1 - 3.2e-21 76.2 0.2 2.8e-11 44.0 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EFI27311.1 - 1e-15 57.9 0.0 7.3e-11 42.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EFI27311.1 - 1.9e-08 34.7 1.2 0.0015 18.8 0.0 4.1 4 2 0 4 4 3 2 AAA domain AAA_16 PF13191.6 EFI27311.1 - 1.1e-07 32.4 0.2 0.041 14.2 0.1 4.1 2 2 2 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EFI27311.1 - 2.1e-07 30.8 0.0 2.2e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 EFI27311.1 - 7.7e-06 26.5 0.0 0.074 13.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EFI27311.1 - 1.4e-05 25.1 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EFI27311.1 - 3.5e-05 23.6 0.4 0.56 9.9 0.0 3.4 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EFI27311.1 - 8.2e-05 22.2 0.0 0.0074 15.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EFI27311.1 - 0.00021 20.7 0.1 0.48 9.8 0.1 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EFI27311.1 - 0.00035 20.9 0.0 0.62 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EFI27311.1 - 0.00055 19.7 0.0 0.074 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EFI27311.1 - 0.0012 19.1 0.8 1.6 8.9 0.0 3.8 4 1 0 4 4 3 1 AAA domain ABC_tran PF00005.27 EFI27311.1 - 0.0019 18.7 1.3 0.07 13.6 0.0 3.2 3 0 0 3 3 3 1 ABC transporter IstB_IS21 PF01695.17 EFI27311.1 - 0.0023 17.7 0.0 0.36 10.5 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 EFI27311.1 - 0.0082 16.1 1.5 7.4 6.5 0.0 3.8 4 1 0 4 4 4 0 NTPase ATP_bind_1 PF03029.17 EFI27311.1 - 0.01 15.6 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.11 EFI27311.1 - 0.014 15.2 0.1 5.6 6.8 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EFI27311.1 - 0.023 14.5 0.0 0.25 11.1 0.0 2.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit TsaE PF02367.17 EFI27311.1 - 0.025 14.6 0.0 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EFI27311.1 - 0.028 14.3 0.1 0.7 9.8 0.0 2.7 3 0 0 3 3 3 0 RsgA GTPase Roc PF08477.13 EFI27311.1 - 0.033 14.4 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EFI27311.1 - 0.042 13.6 0.2 20 4.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EFI27311.1 - 0.045 13.4 0.0 0.5 10.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 EFI27311.1 - 0.048 12.7 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 EFI27311.1 - 0.049 13.8 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EFI27311.1 - 0.053 13.9 0.1 11 6.5 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EFI27311.1 - 0.064 13.0 2.0 4.2 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EFI27311.1 - 0.074 12.8 0.0 0.37 10.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EFI27311.1 - 0.09 12.5 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 EFI27311.1 - 0.14 12.0 0.5 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_6 PF12774.7 EFI27311.1 - 0.23 10.4 0.1 1.4 7.8 0.0 2.2 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region ATPase_2 PF01637.18 EFI27311.1 - 0.27 11.1 7.6 4.3 7.2 0.0 3.8 3 2 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EFI27311.1 - 0.71 10.3 0.0 0.71 10.3 0.0 3.5 3 1 0 3 3 2 0 AAA domain Seryl_tRNA_N PF02403.22 EFI27311.1 - 2.7 8.3 9.9 15 5.9 9.9 2.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4349 PF14257.6 EFI27311.1 - 3.9 6.8 10.0 0.56 9.6 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) MFS_1 PF07690.16 EFI27313.1 - 4.8e-09 35.6 37.6 8.1e-06 25.0 12.2 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EFI27314.1 - 5e-14 52.0 12.5 6.4e-14 51.6 12.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.7 EFI27316.1 - 0.0095 15.8 0.3 0.045 13.7 0.3 2.2 1 0 0 1 1 1 1 F-box-like BacteriocIIc_cy PF12173.8 EFI27319.1 - 0.14 12.4 2.9 0.54 10.5 0.1 2.7 2 1 1 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like Thioredoxin PF00085.20 EFI27320.1 - 1.5e-20 73.1 0.0 4.5e-20 71.6 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EFI27320.1 - 0.00089 19.7 0.0 0.0023 18.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EFI27320.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EFI27320.1 - 0.0019 18.5 0.0 0.17 12.2 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EFI27320.1 - 0.044 13.7 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family ERp29_N PF07912.13 EFI27320.1 - 0.069 13.3 0.0 0.44 10.7 0.0 2.0 2 0 0 2 2 2 0 ERp29, N-terminal domain Glutaredoxin PF00462.24 EFI27320.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin F-box-like PF12937.7 EFI27321.1 - 0.046 13.6 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 EFI27322.1 - 1.2e-10 41.0 5.0 1.5e-10 40.8 3.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EFI27322.1 - 0.028 14.3 8.2 4.3 7.3 0.1 3.9 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 EFI27323.1 - 0.00087 19.1 0.5 0.00087 19.1 0.5 2.5 2 0 0 2 2 2 1 F-box-like COesterase PF00135.28 EFI27324.1 - 4.4e-51 174.3 0.0 6.2e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EFI27324.1 - 5.6e-05 23.1 0.7 0.00027 20.9 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold SH3_9 PF14604.6 EFI27325.1 - 5.2e-30 103.1 3.8 1e-14 54.1 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EFI27325.1 - 3.6e-25 87.3 3.7 5.3e-13 48.4 0.2 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 EFI27325.1 - 1e-23 83.4 0.0 1.7e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EFI27325.1 - 3.4e-18 65.1 0.3 3.5e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain MliC PF09864.9 EFI27325.1 - 0.091 12.7 0.1 0.86 9.6 0.0 2.5 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme SARAF PF06682.12 EFI27325.1 - 0.45 10.1 2.2 1.5 8.4 0.0 2.5 2 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis F-box-like PF12937.7 EFI27331.1 - 1.9e-10 40.5 0.2 3.5e-10 39.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like ESCRT-II PF05871.12 EFI27334.1 - 2.4e-21 76.4 0.3 2.4e-21 76.4 0.3 1.7 2 0 0 2 2 2 1 ESCRT-II complex subunit DEK_C PF08766.11 EFI27334.1 - 0.015 15.2 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 DEK C terminal domain GCP_C_terminal PF04130.13 EFI27334.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal FAD_binding_3 PF01494.19 EFI27335.1 - 4.7e-86 289.2 0.0 2.7e-85 286.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EFI27335.1 - 4.4e-20 72.4 0.0 8.6e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EFI27335.1 - 5.1e-06 25.4 0.1 8e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EFI27335.1 - 7.2e-06 25.3 0.4 1.2e-05 24.6 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EFI27335.1 - 7.5e-06 26.1 0.0 2.4e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EFI27335.1 - 2.7e-05 23.6 0.1 9.6e-05 21.7 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EFI27335.1 - 7e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EFI27335.1 - 0.00018 21.0 0.0 0.00027 20.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EFI27335.1 - 0.00023 20.9 0.1 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EFI27335.1 - 0.00042 19.5 0.2 0.00065 18.9 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EFI27335.1 - 0.00047 20.7 0.1 0.0013 19.2 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EFI27335.1 - 0.00062 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EFI27335.1 - 0.00098 18.5 0.6 0.0018 17.6 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EFI27335.1 - 0.0022 17.1 0.6 0.0073 15.4 0.3 2.0 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EFI27335.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EFI27335.1 - 0.049 13.6 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding ThiF PF00899.21 EFI27335.1 - 0.21 10.9 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 EFI27336.1 - 1.5e-82 277.7 0.0 3e-82 276.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EFI27336.1 - 2.3e-22 79.8 0.0 5.5e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EFI27336.1 - 1.7e-06 27.4 0.4 3.1e-06 26.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EFI27336.1 - 2.8e-06 27.5 0.0 7.5e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EFI27336.1 - 3.6e-06 26.0 0.2 5.8e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EFI27336.1 - 7.2e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EFI27336.1 - 7.9e-05 22.0 0.2 0.00034 20.0 0.1 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EFI27336.1 - 0.00031 21.2 0.0 0.0036 17.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EFI27336.1 - 0.00033 19.8 0.5 0.00095 18.3 0.3 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 EFI27336.1 - 0.00052 19.2 0.2 0.00083 18.5 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EFI27336.1 - 0.00062 19.2 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EFI27336.1 - 0.0007 18.9 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EFI27336.1 - 0.00094 18.5 0.4 0.0016 17.8 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EFI27336.1 - 0.0053 16.4 0.0 0.0092 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase XdhC_C PF13478.6 EFI27336.1 - 0.02 15.4 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.18 EFI27336.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_9 PF13454.6 EFI27336.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EFI27336.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DNA_pol_delta_4 PF04081.13 EFI27337.1 - 2.4e-27 95.8 1.0 2.4e-27 95.8 1.0 2.2 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 Ndc1_Nup PF09531.10 EFI27337.1 - 4.3 5.9 8.8 4.5 5.9 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM247 PF15444.6 EFI27337.1 - 9.5 6.2 6.9 14 5.7 6.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 WLM PF08325.10 EFI27338.1 - 2e-42 145.4 1.1 5.7e-42 144.0 0.1 1.9 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 EFI27338.1 - 1.6e-09 37.4 0.0 3.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EFI27338.1 - 0.0061 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Zincin_1 PF06262.11 EFI27338.1 - 0.019 15.0 0.1 0.085 13.0 0.0 2.1 1 1 1 2 2 2 0 Zincin-like metallopeptidase Ytp1 PF10355.9 EFI27340.1 - 7.4e-56 189.4 14.6 8.2e-55 186.0 14.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EFI27340.1 - 4.5e-25 87.5 2.2 5.2e-25 87.3 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Rxt3 PF08642.10 EFI27340.1 - 0.0015 19.3 0.0 0.0015 19.3 0.0 5.0 5 1 0 5 5 5 1 Histone deacetylation protein Rxt3 Lactamase_B_4 PF13691.6 EFI27341.1 - 8.3e-09 35.0 0.0 8.1e-08 31.8 0.0 2.5 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EFI27341.1 - 2.9e-08 33.5 0.0 9.7e-08 31.8 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Ion_trans PF00520.31 EFI27342.1 - 2.2e-20 72.9 23.7 2.9e-20 72.6 23.7 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EFI27342.1 - 6.4e-12 45.3 6.6 6.4e-12 45.3 6.6 2.7 2 2 1 3 3 3 1 Ion channel Lig_chan PF00060.26 EFI27342.1 - 0.00071 19.4 0.8 0.00071 19.4 0.8 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel XLF PF09302.11 EFI27342.1 - 0.082 13.1 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TolA_bind_tri PF16331.5 EFI27342.1 - 0.16 12.1 0.5 0.27 11.3 0.5 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation CDP-OH_P_transf PF01066.21 EFI27343.1 - 1.8e-14 54.3 0.3 1.8e-14 54.3 0.3 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Glyco_hydro_61 PF03443.14 EFI27344.1 - 6.6e-39 134.0 0.0 8.4e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 KH_1 PF00013.29 EFI27345.1 - 1.4e-08 34.5 0.2 4.8e-07 29.5 0.1 2.5 2 0 0 2 2 2 2 KH domain VPS9 PF02204.18 EFI27347.1 - 4e-31 107.3 0.1 6.1e-31 106.7 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EFI27347.1 - 1.4e-16 60.5 0.4 3.7e-16 59.2 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EFI27347.1 - 1.5e-07 31.0 0.1 4.4e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 CUE domain DMA PF03474.14 EFI27347.1 - 0.0027 17.2 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif Sdh5 PF03937.16 EFI27349.1 - 4e-29 100.4 0.3 5.5e-29 99.9 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase ADH_N PF08240.12 EFI27350.1 - 1e-30 105.8 0.2 1.8e-30 105.0 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EFI27350.1 - 2.4e-13 50.2 0.4 3.9e-11 43.1 0.4 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EFI27350.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 EFI27350.1 - 0.026 14.8 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EFI27350.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FANCL_C PF11793.8 EFI27350.1 - 0.066 13.4 0.4 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Bd3614-deam PF14439.6 EFI27350.1 - 0.11 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase WD40 PF00400.32 EFI27353.1 - 5.2e-21 74.6 13.6 0.0087 16.9 0.6 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Chorein_N PF12624.7 EFI27353.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 N-terminal region of Chorein or VPS13 Methyltransf_16 PF10294.9 EFI27354.1 - 2.2e-15 56.8 0.0 3.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase RED_N PF07808.13 EFI27355.1 - 7.7e-15 55.1 7.9 7.7e-15 55.1 7.9 2.4 3 0 0 3 3 3 1 RED-like protein N-terminal region GST_N_3 PF13417.6 EFI27356.1 - 2.1e-15 56.9 0.1 8e-15 55.0 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EFI27356.1 - 1e-13 51.4 0.0 2.4e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EFI27356.1 - 2.4e-06 27.7 0.0 9.8e-06 25.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EFI27356.1 - 3.1e-06 27.1 0.1 1.6e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EFI27356.1 - 4.7e-06 26.7 0.0 1.6e-05 25.0 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EFI27356.1 - 0.0015 19.2 0.1 0.16 12.7 0.0 2.4 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain DUF4239 PF14023.6 EFI27357.1 - 0.029 14.1 0.8 0.048 13.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Fer4_20 PF14691.6 EFI27357.1 - 0.07 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DNA_ligase_A_M PF01068.21 EFI27358.1 - 2.8e-54 183.9 0.0 5.2e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EFI27358.1 - 4.6e-38 131.3 0.4 9.2e-38 130.3 0.4 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EFI27358.1 - 1.1e-13 51.6 0.0 5.4e-13 49.4 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 EFI27358.1 - 8.4e-13 48.5 0.3 1.6e-07 31.6 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EFI27358.1 - 6.3e-12 46.1 0.1 2.1e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 RNA ligase BRCT PF00533.26 EFI27358.1 - 5.7e-10 39.4 0.3 0.00024 21.4 0.1 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EFI27358.1 - 0.00078 19.4 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 2 twin BRCT domain DUF4073 PF13285.6 EFI27358.1 - 0.085 12.5 0.1 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) Forkhead PF00250.18 EFI27359.1 - 6.8e-25 87.1 0.0 1.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain ACC_central PF08326.12 EFI27362.1 - 2.9e-252 839.1 0.0 3.6e-252 838.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EFI27362.1 - 3.3e-175 583.4 0.0 4.5e-175 583.0 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EFI27362.1 - 7.5e-53 179.2 0.1 3.7e-52 176.9 0.0 2.1 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EFI27362.1 - 7.4e-29 100.5 0.1 1.6e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EFI27362.1 - 8.8e-22 77.3 0.0 4e-20 71.9 0.0 3.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EFI27362.1 - 1.3e-17 63.4 0.1 3e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EFI27362.1 - 0.00021 20.9 0.0 0.0005 19.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EFI27362.1 - 0.0004 20.5 0.0 0.0014 18.7 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EFI27362.1 - 0.00095 19.0 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.22 EFI27362.1 - 0.038 13.6 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain NAD_synthase PF02540.17 EFI27363.1 - 5.5e-23 81.3 0.0 2.2e-22 79.4 0.0 1.8 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 EFI27363.1 - 9.4e-20 71.0 0.0 1.8e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mqo PF06039.15 EFI27363.1 - 0.036 12.6 0.0 0.16 10.5 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) zf-C2H2 PF00096.26 EFI27364.1 - 0.0033 17.8 0.1 0.0077 16.6 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF4764 PF15961.5 EFI27364.1 - 0.02 13.6 0.3 0.024 13.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) zf-C2H2_11 PF16622.5 EFI27364.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type PTCRA PF15028.6 EFI27365.1 - 0.12 12.1 0.0 0.74 9.5 0.0 1.9 2 0 0 2 2 2 0 Pre-T-cell antigen receptor Tropomyosin_1 PF12718.7 EFI27367.1 - 7.9e-33 113.6 37.5 7.9e-33 113.6 37.5 1.7 2 0 0 2 2 2 1 Tropomyosin like Tropomyosin PF00261.20 EFI27367.1 - 2.4e-06 27.1 43.4 6e-05 22.5 18.4 2.8 2 1 1 3 3 3 2 Tropomyosin HOOK PF05622.12 EFI27367.1 - 0.00057 18.2 26.6 0.00057 18.2 26.6 1.6 2 0 0 2 2 2 1 HOOK protein APG6_N PF17675.1 EFI27367.1 - 0.0077 16.8 29.3 0.0077 16.8 29.3 3.2 2 1 1 3 3 3 2 Apg6 coiled-coil region KELK PF15796.5 EFI27367.1 - 0.022 15.2 7.3 0.022 15.2 7.3 4.7 2 2 2 4 4 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3584 PF12128.8 EFI27367.1 - 0.097 10.2 30.1 0.022 12.3 22.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Synaptobrevin PF00957.21 EFI27367.1 - 0.11 12.3 0.5 0.11 12.3 0.5 3.5 3 1 1 4 4 4 0 Synaptobrevin Spc7 PF08317.11 EFI27367.1 - 0.12 11.2 0.1 0.12 11.2 0.1 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein HMMR_N PF15905.5 EFI27367.1 - 0.16 11.4 36.3 0.84 9.0 29.8 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 EFI27367.1 - 0.27 10.8 29.7 0.72 9.4 1.2 2.4 1 1 0 2 2 2 0 Exonuclease VII, large subunit DUF4131 PF13567.6 EFI27367.1 - 0.31 10.7 1.7 0.29 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3450 PF11932.8 EFI27367.1 - 0.48 9.7 40.1 0.14 11.4 15.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EFI27367.1 - 0.69 10.0 21.1 0.59 10.2 6.7 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EFI27367.1 - 1.5 9.0 46.3 0.33 11.1 21.1 2.9 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4686 PF15742.5 EFI27367.1 - 1.7 7.7 39.8 0.056 12.6 29.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) XhlA PF10779.9 EFI27367.1 - 1.9 8.7 32.3 0.76 10.0 1.2 5.0 3 1 2 5 5 5 0 Haemolysin XhlA GAS PF13851.6 EFI27367.1 - 2.9 7.2 44.6 1.5 8.1 20.3 3.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EFI27367.1 - 4.1 7.8 37.9 23 5.4 31.3 3.0 2 1 0 2 2 2 0 Fez1 Tropomyosin PF00261.20 EFI27368.1 - 2.9e-07 30.1 16.6 2.2e-06 27.2 16.6 1.9 1 1 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 EFI27368.1 - 3.5e-05 24.0 15.1 0.012 15.8 4.3 2.0 1 1 1 2 2 2 2 Tropomyosin like DUF4201 PF13870.6 EFI27368.1 - 8.6e-05 22.3 14.8 0.00044 20.0 5.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) ERM PF00769.19 EFI27368.1 - 0.00014 21.8 3.9 0.00014 21.8 3.9 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family Spc7 PF08317.11 EFI27368.1 - 0.00059 18.8 14.1 0.00064 18.7 14.1 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein ATG16 PF08614.11 EFI27368.1 - 0.00062 20.1 17.5 0.011 16.0 17.2 1.9 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EFI27368.1 - 0.002 18.7 15.1 0.0038 17.8 15.1 1.4 1 1 0 1 1 1 1 Apg6 coiled-coil region Laminin_II PF06009.12 EFI27368.1 - 0.0027 17.7 8.3 0.005 16.9 6.9 2.0 1 1 0 1 1 1 1 Laminin Domain II Fib_alpha PF08702.10 EFI27368.1 - 0.0049 17.0 8.6 0.0062 16.7 8.6 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Sec34 PF04136.15 EFI27368.1 - 0.0052 16.7 7.6 0.013 15.4 2.0 2.0 1 1 1 2 2 2 1 Sec34-like family KASH_CCD PF14662.6 EFI27368.1 - 0.0065 16.3 14.5 0.011 15.6 14.1 1.6 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Nup54 PF13874.6 EFI27368.1 - 0.0066 16.6 8.5 0.24 11.5 8.5 2.0 1 1 0 1 1 1 1 Nucleoporin complex subunit 54 DUF4472 PF14739.6 EFI27368.1 - 0.013 16.2 10.8 0.015 16.0 2.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Filament PF00038.21 EFI27368.1 - 0.021 14.4 11.0 0.24 10.9 1.8 2.1 1 1 1 2 2 2 0 Intermediate filament protein Prefoldin_2 PF01920.20 EFI27368.1 - 0.03 14.3 14.9 0.3 11.0 4.5 2.9 1 1 2 3 3 3 0 Prefoldin subunit XhlA PF10779.9 EFI27368.1 - 0.044 14.0 15.3 0.28 11.4 0.6 3.1 1 1 1 3 3 3 0 Haemolysin XhlA HOOK PF05622.12 EFI27368.1 - 0.049 11.8 16.1 0.057 11.6 16.1 1.0 1 0 0 1 1 1 0 HOOK protein GAS PF13851.6 EFI27368.1 - 0.055 12.8 14.7 0.26 10.6 14.7 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 EFI27368.1 - 0.056 13.2 12.2 0.61 9.9 4.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 STAT_alpha PF01017.20 EFI27368.1 - 0.057 13.3 9.5 0.4 10.5 2.8 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain GreA_GreB_N PF03449.15 EFI27368.1 - 0.063 13.4 0.3 0.063 13.4 0.3 4.1 2 2 2 5 5 5 0 Transcription elongation factor, N-terminal Cortex-I_coil PF09304.10 EFI27368.1 - 0.07 13.4 12.6 1.3 9.3 12.6 2.2 1 1 0 1 1 1 0 Cortexillin I, coiled coil LegC3_N PF18654.1 EFI27368.1 - 0.07 12.4 12.4 2.6 7.2 12.4 2.0 1 1 0 1 1 1 0 LegC3 N-terminal coiled-coil domain EzrA PF06160.12 EFI27368.1 - 0.072 11.3 13.0 0.43 8.7 2.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA PspA_IM30 PF04012.12 EFI27368.1 - 0.1 12.2 12.4 0.18 11.4 12.4 1.4 1 1 0 1 1 1 0 PspA/IM30 family TPR_MLP1_2 PF07926.12 EFI27368.1 - 0.11 12.6 15.3 2.2 8.3 3.7 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 EFI27368.1 - 0.11 11.8 10.4 0.46 9.8 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MscS_porin PF12795.7 EFI27368.1 - 0.11 12.0 11.4 0.43 10.1 11.4 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Spc29 PF17082.5 EFI27368.1 - 0.12 12.2 8.5 0.15 11.9 0.6 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 ADIP PF11559.8 EFI27368.1 - 0.13 12.3 14.6 0.54 10.3 3.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rab5-bind PF09311.11 EFI27368.1 - 0.13 11.6 12.4 1.5 8.2 12.4 1.9 1 1 0 1 1 1 0 Rabaptin-like protein T3SSipB PF16535.5 EFI27368.1 - 0.14 12.6 6.3 0.43 11.1 3.3 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB SKA2 PF16740.5 EFI27368.1 - 0.21 11.4 9.7 0.38 10.5 3.0 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 BLOC1_2 PF10046.9 EFI27368.1 - 0.22 11.9 8.7 7.2 7.0 6.1 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 EFI27368.1 - 0.23 12.0 10.3 2 8.9 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 ABC_tran_CTD PF16326.5 EFI27368.1 - 0.23 11.7 14.0 2.1 8.6 3.6 3.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain HAP1_N PF04849.13 EFI27368.1 - 0.23 10.6 13.4 0.15 11.3 5.8 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region BRE1 PF08647.11 EFI27368.1 - 0.25 11.4 12.7 0.25 11.5 2.5 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DASH_Dam1 PF08653.10 EFI27368.1 - 0.26 11.1 3.2 1.2 9.0 0.2 2.8 2 1 1 3 3 3 0 DASH complex subunit Dam1 Fez1 PF06818.15 EFI27368.1 - 0.27 11.7 13.1 1.3 9.4 13.1 1.8 1 1 0 1 1 1 0 Fez1 CC2-LZ PF16516.5 EFI27368.1 - 0.27 11.6 12.6 0.31 11.4 2.0 2.3 1 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YabA PF06156.13 EFI27368.1 - 0.28 11.8 10.0 1.4 9.6 2.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 EFI27368.1 - 0.36 10.3 9.0 0.41 10.2 9.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit bZIP_1 PF00170.21 EFI27368.1 - 0.36 10.9 14.9 0.6 10.2 4.1 2.9 1 1 1 3 3 3 0 bZIP transcription factor DUF4407 PF14362.6 EFI27368.1 - 0.39 10.0 9.4 0.56 9.5 9.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EFI27368.1 - 0.43 10.6 7.6 2.3 8.3 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ax_dynein_light PF10211.9 EFI27368.1 - 0.43 10.5 13.4 0.9 9.4 3.6 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain DHR10 PF18595.1 EFI27368.1 - 0.51 10.4 17.2 1.4 9.0 2.5 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 EFI27368.1 - 0.56 10.6 8.5 10 6.6 1.8 3.3 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 EFI27368.1 - 0.58 10.2 17.5 2.4 8.2 4.8 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.13 EFI27368.1 - 0.6 10.6 9.8 0.8 10.2 1.9 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ZapB PF06005.12 EFI27368.1 - 0.86 10.1 14.8 1.3 9.6 3.3 2.4 1 1 0 2 2 2 0 Cell division protein ZapB DUF3847 PF12958.7 EFI27368.1 - 0.95 9.6 10.5 0.51 10.5 1.3 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF3847) Prefoldin PF02996.17 EFI27368.1 - 1.2 9.0 13.6 1.2 9.1 1.8 2.8 1 1 2 3 3 3 0 Prefoldin subunit THOC7 PF05615.13 EFI27368.1 - 1.3 9.3 14.4 1.4 9.2 4.0 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 Occludin_ELL PF07303.13 EFI27368.1 - 1.5 9.6 9.2 1 10.1 1.4 2.2 1 1 1 2 2 2 0 Occludin homology domain HAUS-augmin3 PF14932.6 EFI27368.1 - 1.6 8.3 12.4 1.7 8.1 2.9 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Wtap PF17098.5 EFI27368.1 - 1.7 8.6 12.1 0.29 11.1 2.0 2.3 2 1 0 2 2 2 0 WTAP/Mum2p family TMPIT PF07851.13 EFI27368.1 - 1.9 7.6 7.6 2.6 7.2 5.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein UPF0449 PF15136.6 EFI27368.1 - 2 8.9 10.6 44 4.6 10.2 2.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Sec8_exocyst PF04048.14 EFI27368.1 - 2.3 8.1 7.4 1.6 8.6 1.8 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Macoilin PF09726.9 EFI27368.1 - 2.5 6.5 12.9 2.9 6.3 12.9 1.0 1 0 0 1 1 1 0 Macoilin family Cluap1 PF10234.9 EFI27368.1 - 3.2 7.1 13.3 0.59 9.5 2.7 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 BST2 PF16716.5 EFI27368.1 - 3.2 8.4 12.4 9.1 6.9 1.9 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 UPF0184 PF03670.13 EFI27368.1 - 3.2 8.2 7.4 1.7 9.1 0.3 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) DUF4140 PF13600.6 EFI27368.1 - 3.4 8.2 11.1 2.2e+03 -0.8 11.1 2.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 EFI27368.1 - 3.6 8.3 11.5 4.2 8.1 2.8 2.9 1 1 2 3 3 3 0 SlyX UPF0242 PF06785.11 EFI27368.1 - 3.6 7.6 12.7 4.9 7.2 12.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EFI27368.1 - 3.7 6.5 13.0 6 5.8 13.0 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PKcGMP_CC PF16808.5 EFI27368.1 - 4.3 7.3 15.3 4.6 7.2 1.0 3.8 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PspB PF06667.12 EFI27368.1 - 4.3 7.5 5.6 11 6.1 0.3 2.8 1 1 2 3 3 3 0 Phage shock protein B DUF4315 PF14193.6 EFI27368.1 - 4.5 7.4 13.1 3.8 7.6 2.0 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4315) GrpE PF01025.19 EFI27368.1 - 4.6 6.9 13.5 10 5.7 5.3 2.2 1 1 1 2 2 2 0 GrpE DUF4164 PF13747.6 EFI27368.1 - 4.9 7.5 16.6 4.8 7.5 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 EFI27368.1 - 4.9 5.6 10.2 13 4.3 10.2 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A NUDE_C PF04880.13 EFI27368.1 - 5.7 7.4 13.9 0.41 11.1 7.2 2.0 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region DivIC PF04977.15 EFI27368.1 - 5.8 6.8 17.6 1.8 8.4 1.8 3.5 1 1 3 4 4 4 0 Septum formation initiator OmpH PF03938.14 EFI27368.1 - 5.9 7.2 12.3 2 8.8 5.7 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FemAB PF02388.16 EFI27368.1 - 6.6 5.5 8.4 5.3 5.8 1.3 2.0 1 1 1 2 2 2 0 FemAB family Swi5 PF07061.11 EFI27368.1 - 6.9 6.8 10.2 1.5e+03 -0.7 10.2 2.9 1 1 0 1 1 1 0 Swi5 DHHC PF01529.20 EFI27369.1 - 7e-19 68.3 2.4 7e-19 68.3 2.4 2.6 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF975 PF06161.11 EFI27369.1 - 4.6 6.9 5.9 1.4 8.7 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Glyco_hydro_47 PF01532.20 EFI27370.1 - 1.3e-130 436.4 0.0 1.5e-130 436.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.13 EFI27371.1 - 7.1e-30 103.4 0.6 1.4e-29 102.5 0.1 1.7 2 0 0 2 2 2 1 Erv1 / Alr family DUF1702 PF08012.11 EFI27371.1 - 0.52 9.1 4.7 0.81 8.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) SHNi-TPR PF10516.9 EFI27373.1 - 4.9e-17 61.1 0.2 3.1e-14 52.1 0.0 2.5 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.6 EFI27373.1 - 1e-14 54.6 5.4 2.5e-07 30.9 1.0 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EFI27373.1 - 1.9e-07 30.6 0.3 0.023 14.5 0.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EFI27373.1 - 2.8e-07 30.1 5.1 0.019 15.1 0.8 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EFI27373.1 - 8.2e-06 25.4 3.6 0.15 11.7 1.7 4.4 2 2 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 EFI27373.1 - 0.0015 19.0 7.3 0.59 10.7 0.1 4.0 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EFI27373.1 - 0.003 17.6 8.8 0.98 9.8 0.3 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EFI27373.1 - 0.0044 17.6 15.7 0.085 13.5 3.4 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EFI27373.1 - 0.0065 15.9 0.9 1.4 8.2 0.0 2.2 2 0 0 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EFI27373.1 - 0.0073 17.0 9.2 15 6.7 0.2 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EFI27373.1 - 0.0075 16.2 4.1 5.5 7.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Sec5 PF15469.6 EFI27373.1 - 0.0091 15.8 0.7 0.19 11.5 0.0 2.5 2 1 0 2 2 2 1 Exocyst complex component Sec5 TPR_10 PF13374.6 EFI27373.1 - 0.01 15.7 0.6 0.87 9.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1664 PF07889.12 EFI27373.1 - 0.074 13.1 1.0 0.57 10.2 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MIT PF04212.18 EFI27373.1 - 0.14 12.2 4.4 5.4 7.2 1.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain FUSC PF04632.12 EFI27373.1 - 1.6 7.2 5.4 0.2 10.2 1.4 1.6 2 1 0 2 2 2 0 Fusaric acid resistance protein family NYD-SP12_N PF15015.6 EFI27373.1 - 2.2 6.6 6.6 3.4 5.9 0.1 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal LRR_4 PF12799.7 EFI27374.1 - 0.013 15.9 8.2 0.83 10.2 0.1 5.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) CNH PF00780.22 EFI27376.1 - 1.2e-75 254.7 0.0 1.9e-75 254.0 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EFI27376.1 - 3.9e-38 130.6 0.1 8e-38 129.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EFI27376.1 - 7.2e-31 107.8 0.0 3.4e-30 105.7 0.0 2.1 1 1 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EFI27376.1 - 7.4e-14 51.6 0.1 1.7e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EFI27376.1 - 0.0003 20.6 0.2 0.0023 17.7 0.1 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain Cation_efflux PF01545.21 EFI27377.1 - 1.1e-48 165.6 0.6 1.7e-32 112.8 0.1 2.1 2 0 0 2 2 2 2 Cation efflux family CiPC PF15800.5 EFI27377.1 - 0.43 10.3 21.7 0.69 9.6 21.7 1.3 1 0 0 1 1 1 0 Clock interacting protein circadian CHCH PF06747.13 EFI27381.1 - 2.1e-06 27.7 3.6 2.8e-06 27.3 3.6 1.2 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 EFI27381.1 - 2.1e-05 24.7 2.1 3e-05 24.2 2.1 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 EFI27381.1 - 0.0045 17.2 1.9 0.0064 16.8 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Nitroreductase PF00881.24 EFI27382.1 - 1.4e-25 90.3 0.0 1.8e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EFI27382.1 - 4.8e-09 36.1 0.0 0.00022 20.9 0.0 2.9 2 1 1 3 3 3 3 Putative TM nitroreductase Ctr PF04145.15 EFI27383.1 - 2.4e-29 102.9 0.0 2.8e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Pheromone PF08015.11 EFI27384.1 - 7e-06 27.0 1.3 0.00038 21.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Ank_2 PF12796.7 EFI27385.1 - 5.4e-24 84.6 0.0 1.2e-14 54.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EFI27385.1 - 8.6e-16 57.6 0.0 0.0029 18.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EFI27385.1 - 1.7e-14 53.7 0.1 1.4e-08 34.8 0.0 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EFI27385.1 - 6.4e-12 45.7 0.0 4.1e-08 33.6 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EFI27385.1 - 1.3e-10 40.6 0.0 0.25 12.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Pyr_redox_2 PF07992.14 EFI27389.1 - 1.2e-32 113.3 0.1 1.7e-32 112.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EFI27389.1 - 8.5e-13 48.7 0.2 1.9e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EFI27389.1 - 6.9e-07 28.8 0.0 7.8e-06 25.4 0.0 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EFI27389.1 - 2e-06 27.9 1.1 0.17 11.9 0.1 3.5 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EFI27389.1 - 0.00012 22.5 0.2 0.12 12.8 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding TrkA_N PF02254.18 EFI27389.1 - 0.00072 19.8 0.0 0.05 13.9 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EFI27389.1 - 0.0052 17.0 0.1 0.44 10.8 0.0 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain K_oxygenase PF13434.6 EFI27389.1 - 0.012 14.8 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EFI27389.1 - 0.16 11.0 0.1 17 4.3 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EFI27389.1 - 0.18 10.6 0.9 4.2 6.1 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 EFI27389.1 - 0.26 10.8 7.8 0.52 9.8 0.3 3.4 1 1 2 4 4 4 0 FAD dependent oxidoreductase GIDA PF01134.22 EFI27389.1 - 8.2 5.4 7.6 15 4.5 0.0 3.3 5 0 0 5 5 5 0 Glucose inhibited division protein A AAA PF00004.29 EFI27390.1 - 6.8e-43 146.2 0.0 4.7e-16 59.4 0.0 5.4 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 EFI27390.1 - 1e-33 116.7 0.0 5.7e-33 114.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 EFI27390.1 - 2.4e-31 109.5 23.1 2.9e-25 89.5 0.0 6.5 6 0 0 6 6 5 2 AAA domain AAA_19 PF13245.6 EFI27390.1 - 8e-18 65.2 0.1 2.3e-05 24.8 0.0 5.6 5 0 0 5 5 5 3 AAA domain AAA_30 PF13604.6 EFI27390.1 - 1.4e-17 64.1 7.5 0.00023 20.9 0.0 6.3 6 0 0 6 6 5 5 AAA domain AAA_lid_6 PF17866.1 EFI27390.1 - 3e-15 56.1 0.3 1.2e-06 28.6 0.0 4.3 4 0 0 4 4 3 2 AAA lid domain AAA_5 PF07728.14 EFI27390.1 - 1.1e-13 51.4 0.4 0.046 13.7 0.0 5.1 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EFI27390.1 - 6.9e-12 45.8 9.6 0.075 13.3 0.0 7.5 6 2 0 6 6 4 4 AAA domain RuvB_N PF05496.12 EFI27390.1 - 1.3e-11 44.5 0.1 0.029 14.1 0.0 4.9 4 1 0 4 4 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EFI27390.1 - 1.3e-11 45.2 2.0 0.47 11.0 0.1 5.5 4 0 0 4 4 4 4 AAA domain Mg_chelatase PF01078.21 EFI27390.1 - 1.5e-10 40.8 0.1 0.13 11.6 0.0 4.6 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EFI27390.1 - 5.2e-10 39.7 0.1 1 9.8 0.0 5.2 4 0 0 4 4 4 3 RNA helicase Viral_helicase1 PF01443.18 EFI27390.1 - 6.2e-10 39.2 0.1 0.13 12.0 0.0 6.2 5 1 0 5 5 5 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EFI27390.1 - 1.3e-09 38.1 0.1 0.13 12.0 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_16 PF13191.6 EFI27390.1 - 7.2e-08 33.0 21.8 0.13 12.6 0.0 6.6 6 0 0 6 6 4 3 AAA ATPase domain AAA_24 PF13479.6 EFI27390.1 - 3.9e-07 30.0 3.0 0.6 9.8 0.1 5.1 5 0 0 5 5 5 2 AAA domain AAA_7 PF12775.7 EFI27390.1 - 4.6e-07 29.5 0.7 0.74 9.3 0.0 4.4 4 0 0 4 4 4 1 P-loop containing dynein motor region PhoH PF02562.16 EFI27390.1 - 7.5e-07 28.8 0.7 5 6.5 0.0 5.4 5 0 0 5 5 5 0 PhoH-like protein AAA_33 PF13671.6 EFI27390.1 - 1.1e-06 28.9 14.6 0.23 11.6 0.0 5.4 5 0 0 5 5 4 3 AAA domain Sigma54_activat PF00158.26 EFI27390.1 - 9.4e-06 25.4 0.0 4.9 6.8 0.0 4.9 4 1 0 4 4 4 0 Sigma-54 interaction domain Torsin PF06309.11 EFI27390.1 - 1.2e-05 25.4 0.1 16 5.6 0.0 5.3 5 0 0 5 5 5 0 Torsin NTPase_1 PF03266.15 EFI27390.1 - 0.00027 20.9 4.3 0.38 10.6 0.0 4.7 5 0 0 5 5 4 1 NTPase MCM PF00493.23 EFI27390.1 - 0.00058 19.0 0.0 1.2 8.2 0.0 2.8 3 0 0 3 3 3 2 MCM P-loop domain AAA_29 PF13555.6 EFI27390.1 - 0.001 18.8 0.4 11 5.8 0.0 4.4 4 0 0 4 4 4 0 P-loop containing region of AAA domain NACHT PF05729.12 EFI27390.1 - 0.0012 18.8 0.3 20 5.0 0.0 4.5 4 0 0 4 4 4 0 NACHT domain AAA_25 PF13481.6 EFI27390.1 - 0.0028 17.2 17.6 0.38 10.3 0.0 5.9 5 1 0 5 5 4 2 AAA domain TsaE PF02367.17 EFI27390.1 - 0.0029 17.6 0.1 12 5.9 0.0 3.9 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EFI27390.1 - 0.0031 16.6 0.1 9.7 5.2 0.0 4.0 4 0 0 4 4 4 0 Type II/IV secretion system protein VirE PF05272.11 EFI27390.1 - 0.0046 16.7 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 Virulence-associated protein E DUF2075 PF09848.9 EFI27390.1 - 0.0054 16.0 26.1 0.011 14.9 0.0 7.4 6 1 0 7 7 6 1 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 EFI27390.1 - 0.0064 16.4 0.3 31 4.4 0.0 4.5 4 0 0 4 4 4 0 RsgA GTPase KTI12 PF08433.10 EFI27390.1 - 0.0068 15.9 0.7 14 5.0 0.0 3.7 4 0 0 4 4 3 0 Chromatin associated protein KTI12 6PF2K PF01591.18 EFI27390.1 - 0.024 14.0 0.0 3.4 6.9 0.0 3.1 3 0 0 3 3 3 0 6-phosphofructo-2-kinase PIF1 PF05970.14 EFI27390.1 - 0.024 13.8 0.0 0.51 9.4 0.0 2.8 2 0 0 2 2 2 0 PIF1-like helicase NB-ARC PF00931.22 EFI27390.1 - 0.028 13.6 1.1 29 3.7 0.0 4.2 5 0 0 5 5 5 0 NB-ARC domain Parvo_NS1 PF01057.17 EFI27390.1 - 0.04 13.0 0.0 3.7 6.5 0.0 3.5 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 SRP54 PF00448.22 EFI27390.1 - 0.062 12.9 0.0 0.062 12.9 0.0 4.9 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EFI27390.1 - 0.081 13.2 0.0 0.081 13.2 0.0 7.0 7 1 1 8 8 6 0 AAA domain CbiA PF01656.23 EFI27390.1 - 0.2 11.7 0.6 1.4e+02 2.5 0.0 4.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 EFI27390.1 - 0.22 12.0 26.3 1.2 9.5 0.4 5.7 5 1 1 6 6 5 0 AAA domain ATPase PF06745.13 EFI27390.1 - 0.94 8.8 13.9 6.6 6.0 0.0 5.1 5 0 0 5 5 4 0 KaiC Vanabin-2 PF11437.8 EFI27390.1 - 2.2 8.5 10.1 4.8 7.4 10.1 1.5 1 0 0 1 1 1 0 Vanadium-binding protein 2 cobW PF02492.19 EFI27390.1 - 5.9 6.4 6.0 30 4.2 0.1 4.5 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain ADH_zinc_N PF00107.26 EFI27391.1 - 6.8e-17 61.7 0.0 2.9e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EFI27391.1 - 3e-06 28.3 0.0 6.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EFI27391.1 - 0.0043 17.0 0.1 0.0092 15.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EFI27391.1 - 0.016 14.7 0.1 0.042 13.3 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 EFI27391.1 - 0.03 13.9 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_N PF08240.12 EFI27391.1 - 0.069 13.0 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DNA_ligase_A_M PF01068.21 EFI27392.1 - 1.5e-23 83.5 0.0 2.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EFI27392.1 - 1.4e-16 61.3 0.0 3.2e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EFI27392.1 - 2.5e-06 27.9 0.0 7.9e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 RNA ligase Lectin_legB PF00139.19 EFI27392.1 - 0.055 13.0 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 Legume lectin domain Pkinase PF00069.25 EFI27394.1 - 5.5e-47 160.4 0.0 9.4e-47 159.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27394.1 - 3.1e-20 72.6 0.0 1.3e-19 70.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EFI27394.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EFI27394.1 - 0.081 12.8 2.7 0.17 11.8 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EFI27394.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NTF2 PF02136.20 EFI27395.1 - 0.068 13.7 0.0 0.09 13.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Glycos_transf_2 PF00535.26 EFI27395.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 NTF2 PF02136.20 EFI27396.1 - 0.14 12.7 0.0 0.18 12.4 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain ZZ PF00569.17 EFI27397.1 - 3.9e-19 68.2 50.2 2.2e-07 30.6 2.5 6.4 6 0 0 6 6 6 5 Zinc finger, ZZ type PB1 PF00564.24 EFI27397.1 - 5e-08 32.8 0.0 1.3e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 EFI27397.1 - 1.8e-05 24.9 42.7 0.006 16.9 0.3 5.6 5 0 0 5 5 5 4 C1 domain PHF5 PF03660.14 EFI27398.1 - 4.2e-34 116.9 1.7 5.6e-34 116.5 1.7 1.1 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EFI27398.1 - 0.0036 15.3 0.5 0.0042 15.0 0.5 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 Tnp_zf-ribbon_2 PF13842.6 EFI27398.1 - 0.17 12.7 4.5 0.81 10.5 1.8 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon DZR PF12773.7 EFI27398.1 - 0.55 10.3 6.2 1.2 9.2 5.4 1.9 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 EFI27398.1 - 4.6 7.7 10.6 0.42 11.0 2.2 2.2 1 1 1 2 2 2 0 C1 domain DUF2231 PF09990.9 EFI27399.1 - 0.13 12.7 1.9 0.2 12.1 0.7 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) Aminotran_3 PF00202.21 EFI27400.1 - 6.9e-78 262.1 0.0 8.4e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Abhydrolase_6 PF12697.7 EFI27400.1 - 0.041 14.5 0.0 0.45 11.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Tim17 PF02466.19 EFI27400.1 - 0.43 11.0 3.8 5 7.6 0.2 2.9 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family HECT PF00632.25 EFI27401.1 - 3.3e-79 266.6 0.0 4.7e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EFI27401.1 - 0.01 15.9 2.6 0.33 11.1 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ARA70 PF12489.8 EFI27401.1 - 0.1 12.8 1.7 0.44 10.7 1.7 2.1 1 0 0 1 1 1 0 Nuclear coactivator UIM PF02809.20 EFI27401.1 - 0.81 9.7 3.8 3.2 7.9 3.8 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif SDH_alpha PF03313.15 EFI27403.1 - 1e-85 287.6 1.2 8.5e-55 186.2 0.0 2.1 2 0 0 2 2 2 2 Serine dehydratase alpha chain SDH_beta PF03315.15 EFI27403.1 - 2.8e-59 199.9 0.0 5e-59 199.1 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain DUF4118 PF13493.6 EFI27405.1 - 0.044 13.6 0.0 0.085 12.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4118) MetallophosC PF16370.5 EFI27405.1 - 0.41 10.9 2.8 3.8 7.7 0.1 2.8 3 0 0 3 3 3 0 C terminal of Calcineurin-like phosphoesterase SSPI PF14098.6 EFI27405.1 - 1.9 8.7 3.0 15 5.8 0.1 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore protein I SnoaL_2 PF12680.7 EFI27407.1 - 0.12 13.0 0.1 0.14 12.8 0.1 1.1 1 0 0 1 1 1 0 SnoaL-like domain Peptidase_M20 PF01546.28 EFI27408.1 - 4.7e-33 114.6 0.0 7.8e-33 113.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EFI27408.1 - 4.4e-12 45.9 0.0 8.9e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EFI27408.1 - 0.00027 20.7 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Ribosomal_L37ae PF01780.19 EFI27409.1 - 3.4e-18 65.5 1.8 3.9e-18 65.3 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1364 PF07102.12 EFI27409.1 - 0.0021 17.9 0.2 0.0025 17.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) AAA_33 PF13671.6 EFI27411.1 - 0.00011 22.3 0.0 0.003 17.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain Velvet PF11754.8 EFI27412.1 - 2.9e-11 43.8 0.6 1.1e-10 41.9 0.0 2.0 2 0 0 2 2 2 1 Velvet factor Pheromone PF08015.11 EFI27413.1 - 7e-06 27.0 1.3 0.00038 21.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI27414.1 - 3e-05 25.0 1.4 0.0016 19.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone HAUS6_N PF14661.6 EFI27419.1 - 2.5e-07 30.5 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 6 N-terminus RINGv PF12906.7 EFI27420.1 - 6.4e-16 58.2 7.6 1.2e-15 57.4 7.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EFI27420.1 - 0.02 15.2 9.5 0.035 14.4 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 EFI27420.1 - 3.9 7.9 4.9 6.9 7.1 4.9 1.3 1 0 0 1 1 1 0 RING-like domain HEAT_EZ PF13513.6 EFI27424.1 - 0.073 13.6 0.1 0.14 12.7 0.1 1.4 1 0 0 1 1 1 0 HEAT-like repeat Anoctamin PF04547.12 EFI27426.1 - 3.7e-111 372.1 1.9 4.5e-111 371.9 1.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel p450 PF00067.22 EFI27427.1 - 1.3e-15 57.1 0.0 1.4e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EFI27428.1 - 9.2e-07 28.0 0.0 1.1e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EFI27429.1 - 9.7e-40 136.6 28.0 1.3e-39 136.1 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EFI27429.1 - 0.00014 20.3 1.0 0.00028 19.3 1.0 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Saf_2TM PF18303.1 EFI27429.1 - 0.032 13.8 1.8 19 4.8 0.2 3.6 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain MFS_1_like PF12832.7 EFI27429.1 - 0.093 11.6 11.5 0.015 14.2 3.3 3.2 1 1 2 3 3 3 0 MFS_1 like family Metallothio_2 PF01439.18 EFI27430.1 - 0.00074 20.4 9.5 0.00074 20.4 9.5 2.2 2 0 0 2 2 2 1 Metallothionein Metallothio_Euk PF12749.7 EFI27430.1 - 0.0018 18.4 32.0 0.0022 18.1 32.0 1.2 1 0 0 1 1 1 1 Eukaryotic metallothionein Metallothio_PEC PF02068.16 EFI27430.1 - 0.045 14.1 34.6 0.13 12.7 34.6 1.7 1 1 0 1 1 1 0 Plant PEC family metallothionein PC-Esterase PF13839.6 EFI27431.1 - 1.7e-07 31.2 3.3 1.2e-05 25.2 2.0 3.2 2 1 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Spa1_C PF18218.1 EFI27431.1 - 0.044 14.2 0.0 4.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain ZZ PF00569.17 EFI27432.1 - 0.00054 19.7 12.8 0.00054 19.7 12.8 2.5 2 0 0 2 2 2 1 Zinc finger, ZZ type TBK1_CCD1 PF18394.1 EFI27432.1 - 0.15 11.6 0.8 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 TANK-binding kinase 1 coiled-coil domain 1 DUF4988 PF16378.5 EFI27432.1 - 0.24 11.1 1.8 0.22 11.2 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function Pro_isomerase PF00160.21 EFI27439.1 - 7.8e-19 68.5 0.0 8.6e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_2 PF12796.7 EFI27440.1 - 2.7e-20 72.7 0.4 1.5e-08 35.1 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EFI27440.1 - 1.2e-15 56.0 0.8 0.072 13.7 0.0 5.6 5 1 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EFI27440.1 - 1.2e-14 54.0 1.1 0.0061 17.0 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EFI27440.1 - 1.3e-13 50.9 0.3 1.6e-06 28.2 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EFI27440.1 - 2.2e-08 34.5 2.3 0.0088 16.6 0.0 4.7 4 2 1 5 5 5 3 Ankyrin repeats (many copies) DUF2569 PF10754.9 EFI27446.1 - 5.6 7.4 13.7 0.2 12.1 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Bac_chlorC PF02043.17 EFI27448.1 - 0.023 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Polysacc_deac_1 PF01522.21 EFI27453.1 - 3.1e-28 98.1 0.0 6.3e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2436 PF10365.9 EFI27453.1 - 0.069 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) ICMT PF04140.14 EFI27454.1 - 1.1e-07 32.2 1.5 5.6e-07 29.9 1.5 2.0 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EFI27454.1 - 0.00027 21.3 1.5 0.0012 19.2 0.1 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EFI27454.1 - 0.0018 17.1 0.1 0.011 14.5 0.1 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EFI27454.1 - 0.12 11.8 0.0 1.4 8.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) TraV PF09676.10 EFI27455.1 - 0.81 10.7 9.6 3.7 8.5 2.1 2.6 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) KDZ PF18758.1 EFI27457.1 - 3.2e-34 118.5 1.6 4e-33 114.9 0.1 2.7 2 1 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI27457.1 - 3.3e-25 88.3 0.1 8.4e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 EFI27457.1 - 8.1e-06 25.4 0.0 1.6e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily CxC1 PF18802.1 EFI27457.1 - 0.001 19.2 0.1 0.0043 17.2 0.0 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases GSH-S_ATP PF02955.16 EFI27458.1 - 0.15 11.4 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF2527 PF10736.9 EFI27459.1 - 0.049 13.5 0.2 0.08 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) KDZ PF18758.1 EFI27460.1 - 1.2e-47 162.4 0.0 2.6e-47 161.3 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI27460.1 - 1.4e-24 86.3 0.1 3.3e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EFI27460.1 - 0.0014 18.7 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases APG17 PF04108.12 EFI27461.1 - 0.068 12.3 1.6 0.13 11.3 1.6 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 AIP3 PF03915.13 EFI27461.1 - 0.13 11.3 2.4 0.14 11.2 1.5 1.5 2 0 0 2 2 2 0 Actin interacting protein 3 FliT PF05400.13 EFI27461.1 - 0.68 10.8 6.7 0.32 11.8 1.5 2.4 2 0 0 2 2 2 0 Flagellar protein FliT RNA_pol_Rpb1_6 PF04992.14 EFI27462.1 - 0.082 12.7 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 HalX PF08663.10 EFI27462.1 - 0.48 10.8 3.3 23 5.4 0.2 2.7 1 1 2 3 3 3 0 HalX domain TMEM51 PF15345.6 EFI27463.1 - 0.072 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EphA2_TM PF14575.6 EFI27464.1 - 0.0068 17.3 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 EFI27464.1 - 0.012 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 EFI27464.1 - 0.024 14.5 0.4 0.066 13.1 0.4 1.8 1 1 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 EFI27464.1 - 0.13 12.0 1.2 0.24 11.2 1.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2755 PF10954.8 EFI27464.1 - 0.16 11.9 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Amnionless PF14828.6 EFI27464.1 - 0.25 10.1 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless Gram_pos_anchor PF00746.21 EFI27464.1 - 0.33 10.9 1.4 0.69 9.9 1.4 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif PRIMA1 PF16101.5 EFI27464.1 - 0.6 10.2 11.8 45 4.1 0.0 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 BatA PF07584.11 EFI27466.1 - 0.16 12.3 0.1 0.65 10.4 0.1 1.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Alpha_GJ PF03229.13 EFI27466.1 - 0.19 12.3 4.3 0.31 11.6 1.9 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J ChlamPMP_M PF07548.11 EFI27467.1 - 0.059 13.3 0.4 0.18 11.7 0.4 1.9 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain DUF2207 PF09972.9 EFI27467.1 - 0.067 11.9 0.0 0.12 11.1 0.0 1.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PTP_tm PF18861.1 EFI27467.1 - 0.16 11.9 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Adap_comp_sub PF00928.21 EFI27469.1 - 4.3e-91 304.9 0.0 9.2e-91 303.9 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EFI27469.1 - 3.5e-07 30.3 0.3 5.9e-07 29.5 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.14 EFI27469.1 - 0.056 12.5 0.2 0.074 12.1 0.2 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 Dyp_perox PF04261.12 EFI27470.1 - 0.015 14.3 0.2 0.6 9.0 0.1 2.8 3 1 0 3 3 3 0 Dyp-type peroxidase family PDH PF02153.17 EFI27473.1 - 4.5e-15 55.3 0.0 6.5e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EFI27473.1 - 7.3e-08 32.9 0.0 1.8e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EFI27473.1 - 4.1e-06 27.1 0.0 8.1e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EFI27473.1 - 2.3e-05 24.4 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EFI27473.1 - 0.0015 18.2 0.0 0.0043 16.7 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EFI27473.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 EFI27473.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EFI27473.1 - 0.085 12.7 0.1 0.24 11.2 0.1 1.8 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EFI27473.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F-box-like PF12937.7 EFI27474.1 - 3.3e-07 30.1 1.0 3.3e-07 30.1 1.0 2.0 2 0 0 2 2 2 1 F-box-like DUF3420 PF11900.8 EFI27474.1 - 0.14 12.3 0.1 0.4 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) PadR PF03551.14 EFI27475.1 - 2.4e-05 24.2 0.1 0.19 11.7 0.0 2.1 1 1 1 2 2 2 2 Transcriptional regulator PadR-like family DUF615 PF04751.14 EFI27475.1 - 0.0029 17.6 0.2 0.025 14.6 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF615) CENP_C_N PF15622.6 EFI27475.1 - 0.0037 16.8 0.8 1.3 8.5 0.1 2.1 1 1 1 2 2 2 2 Kinetochore assembly subunit CENP-C N-terminal fn1 PF00039.18 EFI27475.1 - 0.0098 16.1 0.0 5.7 7.2 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type I domain HTH_28 PF13518.6 EFI27475.1 - 0.013 15.6 0.0 5.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain KcnmB2_inactiv PF09303.10 EFI27475.1 - 0.027 14.3 0.0 8.2 6.3 0.0 2.5 2 0 0 2 2 2 0 KCNMB2, ball and chain domain DUF480 PF04337.12 EFI27475.1 - 0.029 14.5 0.7 8 6.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF480 Suv3_N PF18114.1 EFI27475.1 - 0.046 13.8 0.8 1.3 9.1 0.2 2.1 1 1 1 2 2 2 0 Suv3 helical N-terminal domain Mhr1 PF12829.7 EFI27475.1 - 0.059 13.5 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination YebF PF13995.6 EFI27475.1 - 0.065 13.3 0.1 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 YebF-like protein FUR PF01475.19 EFI27475.1 - 0.097 12.8 0.1 15 5.7 0.0 2.1 1 1 1 2 2 2 0 Ferric uptake regulator family HTH_23 PF13384.6 EFI27475.1 - 0.11 12.3 0.0 20 5.1 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain GSIII_N PF12437.8 EFI27475.1 - 0.12 12.0 0.0 13 5.4 0.0 2.1 1 1 1 2 2 2 0 Glutamine synthetase type III N terminal CTF_NFI PF00859.18 EFI27475.1 - 0.29 11.0 1.2 13 5.6 0.1 2.1 1 1 1 2 2 2 0 CTF/NF-I family transcription modulation region RE_BsaWI PF18643.1 EFI27477.1 - 0.04 13.8 0.0 0.046 13.6 0.0 1.0 1 0 0 1 1 1 0 BsaWI restriction endonuclease type 2 ABC_tran PF00005.27 EFI27478.1 - 8.4e-16 58.7 0.0 1.5e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 EFI27478.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin F-box-like PF12937.7 EFI27483.1 - 0.00017 21.4 0.0 0.74 9.8 0.0 2.6 2 0 0 2 2 2 2 F-box-like F-box_4 PF15966.5 EFI27483.1 - 0.0068 16.3 0.6 0.14 12.0 0.0 2.6 3 0 0 3 3 3 1 F-box DUF3762 PF12591.8 EFI27485.1 - 0.16 12.3 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) KDZ PF18758.1 EFI27486.1 - 1.7e-45 155.4 0.0 2.6e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI27486.1 - 6.5e-18 64.9 0.1 2.3e-17 63.1 0.0 2.0 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Tet_JBP PF12851.7 EFI27488.1 - 9.2e-07 28.5 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HMGL-like PF00682.19 EFI27490.1 - 1.3e-49 169.2 0.0 3.1e-49 167.9 0.0 1.7 1 0 0 1 1 1 1 HMGL-like DnaJ PF00226.31 EFI27490.1 - 1.1e-15 57.5 0.6 5.5e-15 55.2 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain Abhydrolase_6 PF12697.7 EFI27490.1 - 9.1e-05 23.2 0.0 0.0018 18.9 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Borrelia_P83 PF05262.11 EFI27490.1 - 0.014 14.0 18.1 0.021 13.4 18.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RRN9 PF10680.9 EFI27491.1 - 0.43 10.9 2.9 0.49 10.7 2.1 1.5 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Methyltrn_RNA_4 PF09936.9 EFI27492.1 - 0.13 12.1 2.8 0.34 10.7 2.8 1.7 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase LMBR1 PF04791.16 EFI27492.1 - 5.4 5.8 8.1 9.3 5.0 8.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4942 PF13708.6 EFI27493.1 - 0.22 11.5 0.0 27 4.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4942) NYN PF01936.18 EFI27498.1 - 6e-06 26.8 0.0 1.8e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 NYN domain NYN PF01936.18 EFI27499.1 - 3e-14 53.7 0.0 5.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 NYN domain CDC45 PF02724.14 EFI27499.1 - 0.022 13.1 10.6 0.035 12.4 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EFI27499.1 - 2.9 7.2 7.3 5.1 6.3 7.3 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EFI27499.1 - 3.2 6.2 5.7 4.3 5.8 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EFI27499.1 - 6.4 4.7 9.3 8.5 4.3 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi BTV_NS2 PF04514.12 EFI27499.1 - 6.7 5.4 7.1 11 4.8 7.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SET PF00856.28 EFI27500.1 - 4.1e-20 72.8 0.1 4.1e-20 72.8 0.1 3.3 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.22 EFI27500.1 - 4.1e-11 42.5 0.0 5.4e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N-SET PF11764.8 EFI27500.1 - 2.7e-09 37.4 3.4 2.7e-09 37.4 3.4 4.1 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N Nup35_RRM_2 PF14605.6 EFI27500.1 - 0.008 16.2 0.0 0.09 12.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 EFI27500.1 - 0.044 13.4 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated NYN PF01936.18 EFI27501.1 - 2.1e-10 41.3 0.0 3.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 NYN domain Pkinase PF00069.25 EFI27502.1 - 2.4e-31 109.1 0.0 3.5e-30 105.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27502.1 - 2.6e-13 49.8 0.0 2.7e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI27502.1 - 0.0041 15.9 0.1 0.015 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EFI27502.1 - 0.012 15.0 0.3 0.036 13.4 0.3 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3042 PF11240.8 EFI27502.1 - 7.6 6.6 6.0 19 5.4 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SNF5 PF04855.12 EFI27504.1 - 5.4e-67 226.0 0.7 5.4e-67 226.0 0.7 2.5 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 MDM10 PF12519.8 EFI27504.1 - 4.3 6.1 6.9 10 4.9 6.9 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DDHD PF02862.17 EFI27504.1 - 5.6 7.0 13.3 0.092 12.9 1.6 3.3 4 0 0 4 4 4 0 DDHD domain WD40 PF00400.32 EFI27506.1 - 2.1e-05 25.2 2.2 1.1 10.3 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF4407 PF14362.6 EFI27507.1 - 0.7 9.2 8.3 0.064 12.6 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) BPL_N PF09825.9 EFI27513.1 - 1.2e-26 93.7 0.0 1.3e-15 57.4 0.0 2.3 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EFI27513.1 - 5.3e-12 45.8 0.0 1.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family Period_C PF12114.8 EFI27513.1 - 1.7 8.2 8.0 3.9 7.0 7.5 1.8 2 0 0 2 2 2 0 Period protein 2/3C-terminal region MaoC_dehydratas PF01575.19 EFI27517.1 - 9.1e-29 99.5 0.0 1.8e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EFI27517.1 - 2.2e-05 24.6 0.0 0.02 15.0 0.0 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.16 EFI27518.1 - 3e-48 164.9 0.2 4.4e-48 164.4 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EFI27518.1 - 2.1e-05 25.1 0.0 0.012 16.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.10 EFI27518.1 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 CsiD SNF2_N PF00176.23 EFI27519.1 - 6.1e-70 235.7 0.4 1.4e-69 234.5 0.4 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EFI27519.1 - 2.6e-21 76.1 0.0 5.4e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EFI27519.1 - 1.9e-06 28.0 0.1 4.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EFI27519.1 - 0.0036 17.1 0.1 0.62 9.8 0.1 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EFI27519.1 - 0.018 14.2 0.1 0.054 12.6 0.0 1.8 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EFI27519.1 - 0.12 11.5 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PRCC PF10253.9 EFI27519.1 - 0.79 10.5 5.5 0.71 10.6 2.8 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Pterin_bind PF00809.22 EFI27520.1 - 1.6e-52 178.6 0.0 2.4e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EFI27520.1 - 5e-33 113.9 0.0 1.2e-32 112.7 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EFI27520.1 - 9.4e-19 68.0 0.1 2.7e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Dihydroneopterin aldolase Thaumatin PF00314.17 EFI27520.1 - 9.1e-11 41.8 7.4 1.6e-10 41.0 7.4 1.4 1 0 0 1 1 1 1 Thaumatin family Sacchrp_dh_NADP PF03435.18 EFI27520.1 - 0.11 12.8 0.0 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 EFI27522.1 - 4.1e-43 147.5 0.0 6.6e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EFI27522.1 - 0.0002 21.6 1.0 0.0059 16.9 1.0 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EFI27522.1 - 0.0014 19.0 0.1 0.0034 17.8 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding MTS PF05175.14 EFI27522.1 - 0.043 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DAO PF01266.24 EFI27522.1 - 0.052 13.1 0.6 0.17 11.4 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EFI27522.1 - 0.095 12.0 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EFI27522.1 - 0.18 11.0 0.4 0.29 10.3 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain LapA_dom PF06305.11 EFI27522.1 - 0.19 11.6 0.8 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Methyltransf_3 PF01596.17 EFI27523.1 - 1e-36 126.1 0.0 1.3e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EFI27523.1 - 9.6e-18 65.2 0.0 1.5e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EFI27523.1 - 5.6e-09 36.0 0.0 8.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EFI27523.1 - 7.9e-08 32.9 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EFI27523.1 - 1e-07 31.9 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EFI27523.1 - 5.6e-07 30.1 0.0 2.9e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EFI27523.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 EFI27523.1 - 0.00079 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 EFI27523.1 - 0.0035 16.7 0.0 0.005 16.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EFI27523.1 - 0.0082 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EFI27523.1 - 0.032 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Spc7 PF08317.11 EFI27526.1 - 0.012 14.6 0.1 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EFI27526.1 - 0.045 14.0 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 EFI27526.1 - 0.053 13.9 0.1 0.053 13.9 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RasGAP_C PF03836.15 EFI27526.1 - 0.069 13.3 0.1 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 RasGAP C-terminus Atg14 PF10186.9 EFI27526.1 - 0.079 12.0 0.3 0.092 11.8 0.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 EFI27528.1 - 0.0018 18.3 2.2 0.0039 17.2 2.2 1.5 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase TBCC_N PF16752.5 EFI27528.1 - 0.24 11.9 4.6 0.47 10.9 4.6 1.5 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain KDZ PF18758.1 EFI27529.1 - 2.7e-44 151.5 1.9 4.9e-44 150.6 1.9 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI27529.1 - 2.8e-22 78.9 0.9 8.2e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EFI27529.1 - 0.0045 17.1 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 EFI27530.1 - 2.5e-45 154.8 0.0 4.1e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI27530.1 - 6.9e-22 77.6 0.0 1.9e-18 66.6 0.0 3.0 3 0 0 3 3 3 2 CxC2 like cysteine cluster associated with KDZ transposases SET PF00856.28 EFI27533.1 - 1.1e-14 55.2 0.2 3.9e-13 50.1 0.0 2.5 2 1 0 2 2 2 2 SET domain Pheromone PF08015.11 EFI27534.1 - 8 7.6 8.4 53 5.0 0.7 4.1 1 1 3 4 4 4 0 Fungal mating-type pheromone BAH PF01426.18 EFI27536.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 EFI27536.1 - 0.097 12.6 5.5 0.17 11.8 3.1 2.2 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 EFI27536.1 - 0.12 12.6 0.5 0.23 11.8 0.5 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain GCD14 PF08704.10 EFI27537.1 - 0.0065 16.2 0.7 0.013 15.2 0.7 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit LCD1 PF09798.9 EFI27537.1 - 0.017 13.6 3.2 0.02 13.4 3.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein CDC45 PF02724.14 EFI27537.1 - 0.43 8.8 9.5 0.58 8.4 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 EFI27537.1 - 2 7.7 11.9 3.4 6.9 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 EFI27537.1 - 3.3 6.5 4.2 5.3 5.8 4.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Fungal_trans PF04082.18 EFI27538.1 - 5.8e-07 28.8 0.1 1e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EFI27538.1 - 5.8e-05 23.1 14.0 9.7e-05 22.4 14.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC_WH_C PF18137.1 EFI27540.1 - 3.7e-45 153.4 1.2 5.8e-45 152.8 1.2 1.3 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 EFI27540.1 - 1.8e-23 83.2 0.0 2.9e-22 79.2 0.0 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Promethin PF16015.5 EFI27541.1 - 5.2e-06 26.3 18.9 8.6e-06 25.6 18.9 1.3 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 EFI27541.1 - 0.58 8.8 4.1 0.65 8.7 4.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BRO1 PF03097.18 EFI27542.1 - 3.3e-121 404.8 0.2 7e-121 403.7 0.2 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EFI27542.1 - 5.4e-58 196.6 9.2 7.9e-58 196.1 9.2 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Sec2p PF06428.11 EFI27542.1 - 0.28 11.2 6.0 15 5.7 0.2 3.6 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Epimerase PF01370.21 EFI27543.1 - 7.4e-20 71.4 0.0 1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EFI27543.1 - 1.2e-14 54.1 0.0 2e-14 53.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EFI27543.1 - 1.4e-10 41.2 0.0 2.6e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EFI27543.1 - 9.3e-10 38.7 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EFI27543.1 - 2.2e-07 30.3 0.0 1.2e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EFI27543.1 - 4e-06 26.6 0.0 5.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EFI27543.1 - 0.0029 17.5 0.0 0.011 15.6 0.0 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EFI27543.1 - 0.027 13.6 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EFI27543.1 - 0.031 13.7 0.1 0.08 12.4 0.0 1.7 2 0 0 2 2 2 0 short chain dehydrogenase Trs65 PF12735.7 EFI27544.1 - 1.3e-23 83.9 9.1 3.9e-12 46.2 0.0 4.2 4 0 0 4 4 4 3 TRAPP trafficking subunit Trs65 SUIM_assoc PF16619.5 EFI27546.1 - 1.3 9.1 4.4 4.8 7.3 4.4 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GFA PF04828.14 EFI27548.1 - 2.5e-21 75.8 0.4 3.9e-21 75.2 0.4 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme C_GCAxxG_C_C PF09719.10 EFI27548.1 - 0.023 15.0 0.2 8 6.8 0.0 2.1 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Ank_5 PF13857.6 EFI27550.1 - 3.5e-07 30.4 0.0 8e-05 22.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EFI27550.1 - 0.00011 22.6 0.0 0.17 12.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EFI27550.1 - 0.0023 18.3 0.0 0.01 16.3 0.0 2.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EFI27550.1 - 0.0024 18.4 0.0 0.0049 17.4 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EFI27550.1 - 0.04 14.5 0.0 0.47 11.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 EFI27551.1 - 1.4e-05 24.6 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27551.1 - 0.0014 18.0 0.1 0.0039 16.5 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI27551.1 - 0.027 13.3 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EFI27553.1 - 2.5e-06 27.1 0.2 1.3e-05 24.7 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27553.1 - 1.9e-05 24.1 0.2 5.8e-05 22.5 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI27553.1 - 3e-05 23.0 0.0 4.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PFO_beta_C PF12367.8 EFI27553.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Pkinase PF00069.25 EFI27554.1 - 7.4e-12 45.2 0.0 5e-11 42.5 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27554.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI27554.1 - 0.0014 17.5 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI27555.1 - 1.3e-07 31.3 0.0 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27555.1 - 1.6e-05 24.3 0.0 4.2e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI27555.1 - 0.00026 19.9 0.0 0.00044 19.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EFI27556.1 - 1.3e-62 211.6 0.0 2.5e-62 210.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27556.1 - 3.1e-46 157.7 0.0 5.5e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 EFI27556.1 - 9.9e-33 113.6 0.0 2.2e-32 112.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.23 EFI27556.1 - 0.0008 19.4 0.9 0.026 14.5 0.3 2.9 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EFI27556.1 - 0.0023 17.3 0.0 0.016 14.5 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EFI27556.1 - 0.06 12.1 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Glyco_transf_90 PF05686.12 EFI27557.1 - 1.8e-14 53.5 0.4 3.2e-12 46.1 0.3 3.4 3 1 0 3 3 3 1 Glycosyl transferase family 90 Tetraspanin PF00335.20 EFI27557.1 - 0.036 13.8 0.1 0.11 12.2 0.4 1.6 2 0 0 2 2 2 0 Tetraspanin family RasGEF PF00617.19 EFI27560.1 - 1.9e-07 31.4 0.3 3.2e-07 30.7 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain F-box-like PF12937.7 EFI27561.1 - 0.011 15.6 0.0 0.068 13.1 0.0 2.4 2 0 0 2 2 2 0 F-box-like Tetraspanin PF00335.20 EFI27563.1 - 0.33 10.6 6.3 0.21 11.2 2.8 1.9 2 0 0 2 2 2 0 Tetraspanin family adh_short_C2 PF13561.6 EFI27564.1 - 5.8e-55 186.4 0.8 7.7e-55 186.0 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EFI27564.1 - 1.7e-47 161.4 2.8 2.2e-47 161.1 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EFI27564.1 - 5.5e-15 55.7 0.1 7.8e-15 55.2 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EFI27564.1 - 0.0094 15.4 0.4 0.015 14.8 0.4 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EFI27564.1 - 0.017 15.4 0.3 0.043 14.1 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LDcluster4 PF18306.1 EFI27564.1 - 0.031 13.9 0.1 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 SLOG cluster4 family F420_oxidored PF03807.17 EFI27564.1 - 0.12 13.0 0.7 3.1 8.4 0.1 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent zf-CCHC PF00098.23 EFI27569.1 - 0.015 15.4 0.4 0.021 14.9 0.4 1.2 1 0 0 1 1 1 0 Zinc knuckle NADH_u_ox_C PF12853.7 EFI27570.1 - 0.049 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ABC2_membrane PF01061.24 EFI27571.1 - 4.5e-69 232.1 56.9 3.4e-39 134.5 17.3 2.4 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EFI27571.1 - 1e-29 102.3 0.0 1e-29 102.3 0.0 2.1 2 0 0 2 2 1 1 CDR ABC transporter ABC_tran PF00005.27 EFI27571.1 - 5.8e-29 101.4 0.0 6.3e-17 62.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EFI27571.1 - 2.4e-07 30.2 12.6 2.4e-07 30.2 12.6 3.2 2 1 1 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EFI27571.1 - 6e-06 26.3 0.0 6.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EFI27571.1 - 0.00083 19.9 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EFI27571.1 - 0.0041 17.4 0.0 0.016 15.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EFI27571.1 - 0.0085 16.0 0.0 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_16 PF13191.6 EFI27571.1 - 0.01 16.2 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EFI27571.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EFI27571.1 - 0.03 14.5 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EFI27571.1 - 0.053 13.3 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EFI27571.1 - 0.073 12.8 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3464 PF11947.8 EFI27571.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 NACHT PF05729.12 EFI27571.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 EFI27571.1 - 0.18 11.4 0.6 0.42 10.2 0.2 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EFI27571.1 - 0.2 12.2 0.1 0.4 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 EFI27577.1 - 2.8e-43 148.2 0.0 1e-23 83.8 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EFI27577.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC_membrane PF00664.23 EFI27578.1 - 4.3e-36 125.0 5.7 6e-36 124.5 5.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EFI27578.1 - 4.9e-27 95.1 0.0 9.5e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EFI27578.1 - 5.9e-05 23.5 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EFI27578.1 - 0.0025 17.8 0.0 0.0097 15.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EFI27578.1 - 0.008 16.7 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EFI27578.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EFI27578.1 - 0.016 15.1 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EFI27578.1 - 0.016 15.5 0.2 0.1 12.9 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EFI27578.1 - 0.039 13.6 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EFI27578.1 - 0.045 13.3 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EFI27578.1 - 0.073 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 EFI27578.1 - 0.097 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.6 EFI27578.1 - 0.11 12.7 0.1 0.51 10.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EFI27578.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_membrane PF00664.23 EFI27579.1 - 1.2e-46 159.6 4.2 3.4e-46 158.1 4.2 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EFI27579.1 - 1.2e-09 38.9 0.1 1.2e-05 25.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EFI27579.1 - 0.0041 17.5 0.1 0.012 16.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EFI27579.1 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EFI27579.1 - 0.0087 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EFI27579.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EFI27579.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 EFI27579.1 - 0.08 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EFI27579.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EFI27579.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Sigma54_activat PF00158.26 EFI27579.1 - 0.13 11.9 0.0 0.82 9.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EFI27579.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PBP_like_2 PF12849.7 EFI27580.1 - 8.3e-11 42.1 0.1 1.1e-10 41.7 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain Pkinase_fungal PF17667.1 EFI27582.1 - 3e-36 125.1 0.0 4.8e-25 88.2 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EFI27582.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EFI27583.1 - 5.2e-43 147.3 0.0 1.3e-23 83.5 0.0 2.4 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EFI27583.1 - 0.0026 17.2 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PEARLI-4 PF05278.12 EFI27585.1 - 0.0053 16.4 0.5 0.0075 15.9 0.5 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF641 PF04859.12 EFI27585.1 - 0.01 16.2 1.8 0.016 15.5 1.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ADIP PF11559.8 EFI27585.1 - 0.014 15.5 0.9 0.019 15.1 0.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PKcGMP_CC PF16808.5 EFI27585.1 - 0.07 13.0 1.2 0.07 13.0 1.2 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SHE3 PF17078.5 EFI27585.1 - 0.15 11.8 2.9 0.19 11.4 2.9 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 KDZ PF18758.1 EFI27588.1 - 1.9e-62 210.8 0.0 3.1e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 EFI27588.1 - 1.5e-06 28.3 0.1 3.4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EFI27588.1 - 0.082 13.1 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases ZYG-11_interact PF05884.12 EFI27589.1 - 0.033 13.6 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 BLOC1_2 PF10046.9 EFI27589.1 - 0.11 12.8 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_UL7 PF01677.16 EFI27589.1 - 0.11 12.2 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL7 like APG17 PF04108.12 EFI27590.1 - 0.029 13.5 0.3 0.036 13.2 0.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Spc7 PF08317.11 EFI27590.1 - 0.052 12.4 0.6 0.059 12.3 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tet_JBP PF12851.7 EFI27592.1 - 8.7e-17 61.5 0.0 8e-15 55.0 0.0 2.1 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.7 EFI27593.1 - 2.6e-11 43.5 0.0 5.4e-09 35.8 0.0 2.2 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily SAT PF16073.5 EFI27597.1 - 0.2 11.4 1.0 1.4 8.6 0.1 2.5 2 1 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DLH PF01738.18 EFI27598.1 - 3.5e-14 52.9 0.0 5e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family GRA6 PF05084.13 EFI27600.1 - 0.03 14.3 0.1 0.51 10.2 0.0 2.5 2 0 0 2 2 2 0 Granule antigen protein (GRA6) TctB PF07331.11 EFI27600.1 - 0.11 12.8 15.9 18 5.6 0.1 3.8 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1467 PF07330.12 EFI27600.1 - 1.4 8.9 5.8 11 6.0 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1467) ECF_trnsprt PF12822.7 EFI27600.1 - 1.8 8.6 10.6 28 4.8 0.2 3.5 2 2 0 2 2 2 0 ECF transporter, substrate-specific component Bax1-I PF01027.20 EFI27600.1 - 2.2 8.1 10.2 1.3 8.8 0.3 3.4 3 1 0 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 WcbI PF18588.1 EFI27603.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI Frag1 PF10277.9 EFI27605.1 - 0.0068 16.0 3.8 0.0068 16.0 3.8 3.1 2 2 0 3 3 3 2 Frag1/DRAM/Sfk1 family HlyIII PF03006.20 EFI27605.1 - 0.073 12.8 18.1 0.42 10.3 5.1 2.6 3 0 0 3 3 3 0 Haemolysin-III related Gram_pos_anchor PF00746.21 EFI27605.1 - 0.099 12.6 0.9 7.6 6.6 0.0 3.8 4 0 0 4 4 4 0 LPXTG cell wall anchor motif DUF4636 PF15468.6 EFI27605.1 - 0.17 11.6 0.3 9.4 5.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) GRDP-like PF07173.12 EFI27606.1 - 3.4e-15 56.9 0.0 1.6e-14 54.8 0.0 1.9 1 1 1 2 2 2 2 Glycine-rich domain-containing protein-like F-box-like PF12937.7 EFI27607.1 - 1.5e-06 27.9 0.2 7.8e-06 25.7 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EFI27607.1 - 0.022 14.6 2.0 0.05 13.5 0.6 2.4 2 0 0 2 2 2 0 F-box domain SH3_9 PF14604.6 EFI27612.1 - 0.009 15.9 0.1 0.61 10.0 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain UB2H PF14814.6 EFI27612.1 - 0.021 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain SH3_2 PF07653.17 EFI27612.1 - 0.05 13.3 1.6 0.89 9.3 0.1 2.9 3 0 0 3 3 3 0 Variant SH3 domain OTT_1508_deam PF14441.6 EFI27613.1 - 0.0006 19.8 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Abhydrolase_1 PF00561.20 EFI27616.1 - 2.6e-20 73.2 0.2 5.1e-20 72.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EFI27616.1 - 2.3e-12 46.9 0.2 9e-12 45.0 0.0 2.1 2 1 1 3 3 3 1 TAP-like protein Hydrolase_4 PF12146.8 EFI27616.1 - 0.043 13.1 0.0 0.44 9.8 0.0 2.5 2 1 0 2 2 2 0 Serine aminopeptidase, S33 p450 PF00067.22 EFI27617.1 - 1.3e-32 113.1 0.3 1.3e-30 106.6 0.6 2.8 2 1 0 2 2 2 2 Cytochrome P450 DEAD PF00270.29 EFI27619.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EFI27619.1 - 1e-08 35.5 0.0 2.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LRR_4 PF12799.7 EFI27620.1 - 3.7e-24 84.4 27.5 1.3e-07 31.8 0.5 8.8 6 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EFI27620.1 - 3.4e-17 62.0 19.0 4.6e-08 32.7 0.8 8.3 8 1 1 9 9 9 3 Leucine rich repeat LRR_6 PF13516.6 EFI27620.1 - 6.6e-13 47.6 22.0 2.6 8.3 0.1 10.0 11 0 0 11 11 11 7 Leucine Rich repeat LRR_1 PF00560.33 EFI27620.1 - 5.2e-10 38.5 17.0 5.4 8.0 0.0 9.8 9 1 0 9 9 9 3 Leucine Rich Repeat CHAP PF05257.16 EFI27622.1 - 0.00062 20.3 1.7 0.00092 19.7 1.7 1.3 1 0 0 1 1 1 1 CHAP domain Ank_2 PF12796.7 EFI27622.1 - 0.064 13.9 0.0 0.2 12.3 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) TPR_10 PF13374.6 EFI27623.1 - 2.5e-58 192.5 5.8 6.3e-06 25.9 0.2 14.4 14 0 0 14 14 14 12 Tetratricopeptide repeat CHAT PF12770.7 EFI27623.1 - 1.2e-20 74.2 0.0 2.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EFI27623.1 - 3.8e-14 52.7 6.1 1.2 9.5 0.0 11.3 5 5 8 13 13 13 3 Tetratricopeptide repeat Ank_4 PF13637.6 EFI27623.1 - 7e-10 39.3 0.2 3.5e-06 27.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EFI27623.1 - 1.4e-08 35.2 0.1 1.5e-06 28.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) TPR_17 PF13431.6 EFI27623.1 - 8.7e-08 32.0 1.0 2.9 8.5 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 EFI27623.1 - 5.5e-05 22.8 4.1 77 3.4 0.0 9.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 EFI27623.1 - 0.00031 21.3 9.6 49 5.1 0.1 8.7 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EFI27623.1 - 0.00033 20.6 0.4 67 4.1 0.0 7.1 8 0 0 8 8 7 0 Tetratricopeptide repeat Ank_5 PF13857.6 EFI27623.1 - 0.00072 19.8 0.1 0.94 9.9 0.1 3.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EFI27623.1 - 0.01 16.3 0.1 30 5.6 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat TPR_2 PF07719.17 EFI27623.1 - 0.036 14.2 3.6 86 3.6 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat Ank PF00023.30 EFI27623.1 - 0.073 13.5 0.1 3.7 8.2 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat DUF1977 PF09320.11 EFI27625.1 - 0.041 14.1 0.1 0.041 14.1 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1977) LRS4 PF10422.9 EFI27625.1 - 0.17 11.4 1.7 0.25 10.9 1.7 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 RHH_1 PF01402.21 EFI27627.1 - 0.74 9.8 3.8 1.7 8.7 0.1 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family F-box-like PF12937.7 EFI27628.1 - 7e-05 22.6 0.1 0.00015 21.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EFI27628.1 - 8.3e-05 22.4 0.2 0.00023 21.0 0.2 1.7 1 0 0 1 1 1 1 F-box domain ArfGap PF01412.18 EFI27628.1 - 1.2 9.2 6.2 0.26 11.4 0.7 2.7 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf Radial_spoke_3 PF06098.11 EFI27628.1 - 1.6 7.9 5.1 3.8 6.7 5.1 1.5 1 0 0 1 1 1 0 Radial spoke protein 3 CtIP_N PF10482.9 EFI27628.1 - 2.1 8.4 7.9 2.9 7.9 1.7 2.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Cyclin PF08613.11 EFI27629.1 - 2e-36 125.8 7.6 9.2e-25 87.9 0.0 4.9 4 1 2 6 6 6 2 Cyclin DUF3098 PF11297.8 EFI27635.1 - 0.016 14.8 0.2 0.04 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) DUF3246 PF11596.8 EFI27635.1 - 0.27 10.7 4.0 0.43 10.0 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Tti2 PF10521.9 EFI27638.1 - 7.2e-38 130.7 0.0 2.5e-37 129.0 0.0 1.8 2 0 0 2 2 2 1 Tti2 family NCBP3 PF10309.9 EFI27639.1 - 2.4e-10 40.1 0.0 3.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 EFI27639.1 - 0.002 18.7 13.2 0.002 18.7 13.2 4.0 3 1 1 4 4 4 3 C-terminal duplication domain of Friend of PRMT1 MafB19-deam PF14437.6 EFI27640.1 - 5.7e-23 81.2 0.2 1.2e-22 80.1 0.2 1.5 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EFI27640.1 - 2.2e-22 78.8 0.1 3.2e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 EFI27640.1 - 0.00063 19.8 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EFI27640.1 - 0.0034 17.5 0.0 0.0052 16.9 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 Bd3614-deam PF14439.6 EFI27640.1 - 0.0035 17.4 1.2 0.034 14.2 1.2 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 EFI27640.1 - 0.0077 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EFI27640.1 - 0.01 15.9 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 EFI27640.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 EFI27640.1 - 0.078 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 EFI27640.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase CARMIL_C PF16000.5 EFI27642.1 - 0.11 12.0 2.5 0.18 11.4 2.5 1.2 1 0 0 1 1 1 0 CARMIL C-terminus AA_permease_2 PF13520.6 EFI27643.1 - 7.8e-47 160.1 52.9 9.3e-47 159.8 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EFI27643.1 - 7.5e-24 84.2 43.3 9.5e-24 83.8 43.3 1.1 1 0 0 1 1 1 1 Amino acid permease PGM_PMM_III PF02880.16 EFI27643.1 - 0.16 12.2 0.5 1.5 9.0 0.2 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III GTP_EFTU PF00009.27 EFI27644.1 - 1.3e-33 116.2 0.0 1.3e-33 116.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EFI27644.1 - 6.3e-20 71.3 0.0 1.7e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EFI27644.1 - 8.8e-14 51.7 7.0 1.8e-09 37.8 0.0 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EFI27644.1 - 4.9e-07 29.8 0.0 2.1e-06 27.8 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EFI27644.1 - 1.4e-05 25.3 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 EFI27644.1 - 6.7e-05 22.7 0.1 0.00019 21.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Ras PF00071.22 EFI27644.1 - 0.024 14.3 0.1 0.12 12.0 0.1 2.2 1 1 0 1 1 1 0 Ras family ATP_bind_1 PF03029.17 EFI27644.1 - 0.032 14.0 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EFI27644.1 - 0.062 13.6 0.5 0.94 9.7 0.5 2.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EFI27644.1 - 0.065 13.1 0.9 0.71 9.8 0.2 2.7 1 1 1 2 2 2 0 RsgA GTPase Arf PF00025.21 EFI27645.1 - 1.7e-66 223.0 0.1 6.9e-65 217.8 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EFI27645.1 - 4.9e-13 49.0 0.6 4.2e-07 29.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EFI27645.1 - 1.2e-11 44.8 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EFI27645.1 - 9.7e-09 34.9 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EFI27645.1 - 3.2e-07 30.1 0.0 3.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EFI27645.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EFI27645.1 - 1.9e-06 27.9 0.0 3.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EFI27645.1 - 0.016 14.9 0.0 0.095 12.4 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EFI27645.1 - 0.062 13.2 0.2 0.2 11.5 0.2 1.8 1 1 0 1 1 1 0 NACHT domain cobW PF02492.19 EFI27645.1 - 0.1 12.2 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EFI27645.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2025 PF09634.10 EFI27645.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) Cyclin_N PF00134.23 EFI27651.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.7 1 1 0 1 1 1 0 Cyclin, N-terminal domain DUF2618 PF10940.8 EFI27651.1 - 0.093 12.5 0.4 0.25 11.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) GAS2 PF02187.17 EFI27652.1 - 3.5e-12 46.2 0.1 1e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Fez1 PF06818.15 EFI27653.1 - 0.031 14.8 6.9 0.045 14.2 6.9 1.3 1 0 0 1 1 1 0 Fez1 GrpE PF01025.19 EFI27653.1 - 0.48 10.1 5.5 0.91 9.2 2.4 2.1 1 1 1 2 2 2 0 GrpE ZapB PF06005.12 EFI27653.1 - 2.7 8.5 10.5 0.52 10.8 4.4 2.8 2 1 1 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 EFI27653.1 - 6.5 7.3 11.1 2.7 8.5 6.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region ThiF PF00899.21 EFI27654.1 - 5.5e-111 369.8 0.0 1.7e-70 237.2 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EFI27654.1 - 3e-90 302.6 0.0 4.7e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EFI27654.1 - 4.5e-35 119.7 0.7 9.2e-35 118.7 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EFI27654.1 - 7.4e-33 113.1 0.3 1.6e-32 112.1 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EFI27654.1 - 5.6e-27 93.7 0.5 1.6e-26 92.3 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Aminotran_3 PF00202.21 EFI27655.1 - 1.1e-103 347.0 0.0 1.7e-103 346.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EFI27655.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EFI27655.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 2 0 0 2 2 2 0 Beta-eliminating lyase Alpha_kinase PF02816.18 EFI27656.1 - 2e-05 24.8 0.0 2.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family MT-A70 PF05063.14 EFI27657.1 - 2.6e-55 187.0 0.1 6.3e-55 185.7 0.1 1.6 1 1 0 1 1 1 1 MT-A70 PXPV PF12778.7 EFI27658.1 - 0.18 11.7 3.9 0.26 11.2 3.9 1.2 1 0 0 1 1 1 0 PXPV repeat (3 copies) RRM_1 PF00076.22 EFI27660.1 - 1.2e-17 63.5 0.0 1.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.20 EFI27661.1 - 3.4e-17 62.4 0.0 4.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Tau95 PF09734.9 EFI27662.1 - 5.3e-35 121.3 2.6 5.3e-35 121.3 2.6 2.9 2 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EFI27662.1 - 2.9e-31 108.3 0.2 6.4e-30 104.0 0.0 2.9 3 0 0 3 3 3 1 Tau95 Triple barrel domain Ribosomal_L29e PF01779.17 EFI27663.1 - 5.1e-24 84.3 12.5 6.3e-24 84.0 12.5 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF4451 PF14616.6 EFI27664.1 - 1.4e-32 112.4 0.4 2.3e-32 111.8 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Vfa1 PF08432.10 EFI27665.1 - 1.1e-40 139.9 8.5 1.3e-40 139.7 8.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 EFI27665.1 - 0.0035 16.8 8.5 0.0052 16.2 8.5 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger SpoIIIAH PF12685.7 EFI27665.1 - 0.0044 16.9 3.5 0.0049 16.7 3.5 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein NARP1 PF12569.8 EFI27665.1 - 0.11 11.4 8.8 0.14 11.0 8.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3006 PF11213.8 EFI27665.1 - 0.53 10.6 5.5 0.74 10.1 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Menin PF05053.13 EFI27665.1 - 1.4 7.2 5.7 1.6 7.0 5.7 1.1 1 0 0 1 1 1 0 Menin FYDLN_acid PF09538.10 EFI27665.1 - 2.1 9.1 12.0 1.5 9.6 10.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF1682 PF07946.14 EFI27665.1 - 2.1 7.5 11.1 0.029 13.6 4.4 1.3 2 0 0 2 2 1 0 Protein of unknown function (DUF1682) CPSF100_C PF13299.6 EFI27665.1 - 2.7 8.1 8.1 3.5 7.8 8.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EFI27665.1 - 2.8 7.7 12.4 3.4 7.4 12.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TAF4 PF05236.14 EFI27665.1 - 3.4 7.3 16.2 5.1 6.8 14.4 1.8 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CDC45 PF02724.14 EFI27665.1 - 3.5 5.8 10.4 4.2 5.6 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 EFI27665.1 - 5.1 5.5 11.9 6 5.2 11.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Connexin PF00029.19 EFI27665.1 - 5.4 6.7 6.2 7.2 6.3 6.2 1.3 1 0 0 1 1 1 0 Connexin Hid1 PF12722.7 EFI27665.1 - 5.6 5.0 7.1 6.4 4.8 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.13 EFI27665.1 - 6 5.5 9.3 6.4 5.4 9.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 U79_P34 PF03064.16 EFI27665.1 - 6.7 6.0 12.8 8.6 5.6 12.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 EFI27665.1 - 7.7 5.2 9.6 9.5 4.9 9.6 1.1 1 0 0 1 1 1 0 Presenilin Proteasome PF00227.26 EFI27666.1 - 3.3e-54 183.3 0.0 4.6e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EFI27666.1 - 7.9e-12 44.6 0.1 7.9e-12 44.6 0.1 2.5 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature GTP_EFTU PF00009.27 EFI27667.1 - 1e-31 110.0 0.0 1.4e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EFI27667.1 - 1.6e-15 57.4 0.0 8.5e-15 55.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EFI27667.1 - 4.8e-07 30.1 0.1 9.2e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EFI27667.1 - 5.6e-05 23.2 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EFI27667.1 - 0.038 13.9 0.6 0.11 12.4 0.6 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SRPRB PF09439.10 EFI27667.1 - 0.15 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HBS1_N PF08938.10 EFI27668.1 - 7.5e-10 39.0 0.5 1.5e-09 38.0 0.5 1.5 1 0 0 1 1 1 1 HBS1 N-terminus Arf PF00025.21 EFI27668.1 - 0.24 10.8 0.6 0.41 10.1 0.6 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family SSB PF00436.25 EFI27669.1 - 1.6e-17 63.4 0.0 2.1e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 EFI27669.1 - 0.047 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNB PF00773.19 EFI27670.1 - 4.6e-94 315.4 0.0 7.2e-94 314.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EFI27670.1 - 1.9e-28 99.1 0.2 4.5e-28 97.8 0.2 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EFI27670.1 - 1.7e-23 82.4 0.5 3.6e-23 81.3 0.5 1.6 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EFI27670.1 - 5.8e-15 55.1 0.0 2e-14 53.3 0.0 2.1 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EFI27670.1 - 6.3e-09 35.9 3.0 0.0004 20.5 0.0 5.0 4 1 1 5 5 5 2 Cold shock domain PIN_4 PF13638.6 EFI27670.1 - 1.2e-06 28.8 0.0 3.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.11 EFI27670.1 - 0.012 15.3 2.0 0.019 14.6 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain DSPc PF00782.20 EFI27671.1 - 2.1e-28 98.8 0.0 2.6e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EFI27671.1 - 0.0021 18.3 0.1 0.0049 17.1 0.0 1.6 2 0 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EFI27671.1 - 0.0029 17.2 0.1 0.0039 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase OppC_N PF12911.7 EFI27673.1 - 0.021 14.8 3.2 0.036 14.1 0.2 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF4256 PF14066.6 EFI27674.1 - 0.24 11.1 2.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) Jnk-SapK_ap_N PF09744.9 EFI27674.1 - 1.7 8.8 17.5 2.7 8.2 16.8 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Tho2 PF11262.8 EFI27674.1 - 1.9 7.6 8.3 3.2 6.9 8.3 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 BBP1_C PF15272.6 EFI27674.1 - 6.7 6.5 15.1 0.38 10.6 7.2 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal V_ATPase_I PF01496.19 EFI27674.1 - 9.2 4.0 6.9 13 3.6 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpb1_5 PF04998.17 EFI27675.1 - 3e-86 289.2 0.0 6.9e-86 288.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EFI27675.1 - 5.3e-55 186.1 0.1 9.6e-55 185.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EFI27675.1 - 1.5e-37 129.0 0.0 3.7e-37 127.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EFI27675.1 - 9.7e-30 104.0 3.7 2.6e-23 82.8 0.1 3.7 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EFI27675.1 - 1.2e-20 73.5 0.0 3.2e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Lactamase_B_2 PF12706.7 EFI27678.1 - 8.1e-09 35.3 0.2 0.0017 17.9 0.0 2.6 1 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EFI27678.1 - 7.2e-07 28.8 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EFI27678.1 - 9.8e-07 29.0 0.1 2.2e-06 27.8 0.1 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 EFI27678.1 - 0.017 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Pex14_N PF04695.13 EFI27679.1 - 7.6e-09 36.4 0.3 7.6e-09 36.4 0.3 3.4 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PUMA PF15826.5 EFI27680.1 - 0.21 11.8 1.5 0.2 11.8 0.4 1.5 2 0 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Pkinase PF00069.25 EFI27681.1 - 4.8e-63 213.0 0.0 2.1e-41 142.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27681.1 - 1.3e-27 96.8 0.0 1.5e-22 80.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EFI27681.1 - 2.3e-12 47.0 0.0 4.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EFI27681.1 - 4.4e-08 32.8 0.2 0.0004 19.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EFI27681.1 - 0.0003 20.8 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EFI27681.1 - 0.00046 19.9 0.0 0.48 10.0 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EFI27681.1 - 0.0045 16.0 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EFI27681.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EFI27681.1 - 0.022 14.3 0.1 0.051 13.2 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EFI27681.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.7 EFI27681.1 - 0.1 12.9 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 PAS domain Pkinase_fungal PF17667.1 EFI27681.1 - 0.18 10.6 0.4 0.54 9.0 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase VMA21 PF09446.10 EFI27682.1 - 1.9e-07 31.1 0.7 2.2e-07 30.9 0.7 1.1 1 0 0 1 1 1 1 VMA21-like domain DUF1418 PF07214.12 EFI27682.1 - 0.14 12.0 0.0 0.14 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) MMR_HSR1_Xtn PF16897.5 EFI27683.1 - 2.8e-40 136.6 1.3 1.2e-39 134.6 0.7 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EFI27683.1 - 1.8e-24 85.5 0.1 3.3e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EFI27683.1 - 2.4e-20 72.7 0.0 5.6e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EFI27683.1 - 4.8e-08 32.7 0.2 1.3e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Glyco_hydro_66 PF13199.6 EFI27683.1 - 0.0059 15.3 0.0 0.0083 14.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 MeaB PF03308.16 EFI27683.1 - 0.013 14.5 1.3 0.028 13.4 0.1 2.0 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EFI27683.1 - 0.027 14.5 0.3 10 6.1 0.0 2.5 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 EFI27683.1 - 0.24 11.3 2.6 6.2 6.7 0.1 3.3 3 1 0 3 3 3 0 RsgA GTPase ATE_C PF04377.15 EFI27684.1 - 1.4e-45 155.2 0.5 5e-45 153.4 0.4 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus Brix PF04427.18 EFI27685.1 - 2.1e-27 96.5 0.4 2.6e-27 96.2 0.4 1.1 1 0 0 1 1 1 1 Brix domain Cys_Met_Meta_PP PF01053.20 EFI27686.1 - 5.1e-60 203.0 0.0 8.8e-60 202.2 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_1 PF00076.22 EFI27687.1 - 9.9e-16 57.3 0.0 3.6e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EFI27687.1 - 0.11 12.5 0.0 19 5.3 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain AhpC-TSA PF00578.21 EFI27688.1 - 9.5e-32 109.5 0.0 1.2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EFI27688.1 - 1.6e-13 50.6 0.0 2.1e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EFI27688.1 - 1e-10 41.3 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Proteasome PF00227.26 EFI27689.1 - 3.6e-29 101.6 0.1 4.6e-24 84.9 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Aldedh PF00171.22 EFI27690.1 - 1.5e-156 521.5 1.5 1.4e-76 257.9 0.1 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family Thiolase_N PF00108.23 EFI27691.1 - 4.4e-87 291.7 0.2 6.5e-87 291.2 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EFI27691.1 - 2.7e-38 130.4 0.9 2.7e-38 130.4 0.9 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain Autophagy_act_C PF03987.15 EFI27691.1 - 6.4e-16 58.7 0.1 1.4e-15 57.6 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain ketoacyl-synt PF00109.26 EFI27691.1 - 0.002 17.8 2.0 0.0085 15.7 2.0 1.9 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain 7TMR-HDED PF07697.11 EFI27691.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 7TM-HD extracellular DUF1640 PF07798.11 EFI27692.1 - 5.7e-42 143.7 8.6 7.4e-42 143.4 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GST_N PF02798.20 EFI27692.1 - 1.4e-10 41.3 0.1 3.2e-10 40.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EFI27692.1 - 3.2e-05 24.2 0.0 6.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EFI27692.1 - 3.3e-05 24.1 0.0 7.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lipoprotein_7 PF01540.16 EFI27692.1 - 0.0064 15.8 1.6 0.0089 15.4 1.6 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein ApoLp-III PF07464.11 EFI27692.1 - 0.068 13.3 3.4 0.092 12.8 3.4 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Microvir_H PF04687.12 EFI27692.1 - 0.09 12.1 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Fzo_mitofusin PF04799.13 EFI27692.1 - 0.13 11.8 5.3 0.28 10.7 3.7 2.0 1 1 1 2 2 2 0 fzo-like conserved region PIN_8 PF18476.1 EFI27692.1 - 0.32 10.8 4.1 0.45 10.3 4.1 1.1 1 0 0 1 1 1 0 PIN like domain DUF1664 PF07889.12 EFI27692.1 - 1.1 9.3 6.5 3 7.9 5.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Metal_resist PF13801.6 EFI27692.1 - 1.2 9.4 6.6 15 5.8 0.0 2.8 2 1 0 2 2 2 0 Heavy-metal resistance DUF4404 PF14357.6 EFI27692.1 - 1.9 9.2 5.9 2.7 8.7 3.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DEAD PF00270.29 EFI27693.1 - 4.8e-18 65.5 0.0 7.7e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EFI27693.1 - 1.4e-07 31.8 0.0 3.2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 EFI27693.1 - 0.0005 19.8 0.1 0.11 12.3 0.1 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sua5_yciO_yrdC PF01300.18 EFI27694.1 - 4.5e-52 176.1 0.0 1e-51 175.0 0.0 1.6 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EFI27694.1 - 1.5e-29 103.3 0.0 3.1e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Complex1_LYR_2 PF13233.6 EFI27694.1 - 8.1e-16 58.5 0.4 1.6e-15 57.6 0.4 1.5 1 0 0 1 1 1 1 Complex1_LYR-like MFS_1 PF07690.16 EFI27695.1 - 1.5e-39 135.9 26.5 1.8e-39 135.6 26.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TraU PF06834.11 EFI27696.1 - 0.0097 15.2 0.0 0.0097 15.2 0.0 1.0 1 0 0 1 1 1 1 TraU protein Sedlin_N PF04628.13 EFI27697.1 - 4.9e-21 75.2 0.1 6.4e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Mito_carr PF00153.27 EFI27698.1 - 2.7e-48 161.8 9.7 1.9e-16 59.7 0.6 3.4 3 1 1 4 4 4 3 Mitochondrial carrier protein PrcB_C PF14343.6 EFI27698.1 - 0.0057 16.7 0.1 1.8 8.8 0.1 2.5 2 0 0 2 2 2 2 PrcB C-terminal FF PF01846.19 EFI27699.1 - 8.2e-42 141.2 19.3 1.6e-13 50.6 0.0 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.26 EFI27699.1 - 3.4e-12 46.2 5.8 3.3e-06 27.1 0.9 2.8 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EFI27699.1 - 1.6e-06 28.7 9.2 0.0066 17.1 0.1 4.3 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain HSP90 PF00183.18 EFI27700.1 - 4.6e-134 448.1 4.1 6e-134 447.8 4.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EFI27700.1 - 8.7e-08 32.1 0.4 2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EFI27700.1 - 1.2e-06 29.0 0.0 2.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TCTP PF00838.17 EFI27700.1 - 0.48 10.7 4.3 19 5.6 0.0 3.0 3 0 0 3 3 3 0 Translationally controlled tumour protein Yos1 PF08571.10 EFI27701.1 - 1e-21 77.0 0.0 1.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Yos1-like TFIIF_alpha PF05793.12 EFI27702.1 - 2.1e-11 43.1 32.5 0.00022 20.0 23.6 3.4 3 0 0 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.9 EFI27702.1 - 3.8 6.6 7.9 6.2 5.9 7.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein HLH PF00010.26 EFI27703.1 - 4.4e-15 55.4 0.7 7.9e-15 54.6 0.7 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NYD-SP28_assoc PF14775.6 EFI27703.1 - 0.022 14.9 0.4 0.041 14.0 0.4 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain HALZ PF02183.18 EFI27703.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.18 EFI27703.1 - 0.12 12.7 0.3 0.23 11.8 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family SPX PF03105.19 EFI27703.1 - 0.3 11.0 8.8 0.48 10.3 8.8 1.4 1 0 0 1 1 1 0 SPX domain APG6_N PF17675.1 EFI27703.1 - 0.31 11.6 1.6 0.44 11.1 1.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Cupin_8 PF13621.6 EFI27704.1 - 5.1e-56 190.2 0.0 9.1e-56 189.4 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EFI27704.1 - 0.0064 16.9 0.0 0.067 13.6 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EFI27704.1 - 0.023 14.2 0.0 0.059 12.8 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_2 PF07883.11 EFI27704.1 - 0.11 12.2 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Cupin domain TraF_2 PF13729.6 EFI27706.1 - 0.085 12.2 9.3 0.17 11.2 0.6 2.9 2 1 1 3 3 3 0 F plasmid transfer operon, TraF, protein UPF0184 PF03670.13 EFI27706.1 - 0.34 11.3 16.2 0.11 12.9 0.7 4.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0184) DUF4407 PF14362.6 EFI27706.1 - 1.6 8.0 48.0 5.1 6.4 15.7 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EFI27706.1 - 2 9.0 14.5 3.3 8.2 0.7 4.3 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3818 PF12825.7 EFI27707.1 - 8.1e-132 439.3 0.1 1.1e-131 438.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EFI27707.1 - 4.5e-33 114.0 0.1 9.9e-33 112.9 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EFI27707.1 - 1.1e-09 38.2 0.2 7.2e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 PX domain Hormone_1 PF00103.20 EFI27707.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Somatotropin hormone family CDC45 PF02724.14 EFI27707.1 - 0.57 8.4 4.3 1 7.6 4.3 1.3 1 0 0 1 1 1 0 CDC45-like protein LON_substr_bdg PF02190.16 EFI27708.1 - 5e-10 39.6 0.0 8.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EFI27708.1 - 2e-07 30.7 30.3 5e-06 26.3 17.0 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EFI27708.1 - 9.6e-07 28.9 25.2 2.8e-05 24.2 4.1 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EFI27708.1 - 2.1e-05 24.3 26.9 0.0024 17.7 13.5 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EFI27708.1 - 0.00041 20.6 29.7 0.001 19.3 14.2 2.9 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 EFI27708.1 - 0.0022 17.9 29.8 0.058 13.3 14.8 3.1 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EFI27708.1 - 0.003 17.5 30.1 0.1 12.7 7.6 3.4 2 1 0 2 2 2 2 RING-type zinc-finger ORC6 PF05460.13 EFI27708.1 - 0.041 13.2 0.4 0.041 13.2 0.4 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) zf-RING_10 PF16685.5 EFI27708.1 - 0.069 13.3 20.9 0.39 10.9 7.3 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 EFI27708.1 - 0.13 12.2 31.7 1.6 8.8 16.0 3.1 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_6 PF14835.6 EFI27708.1 - 1.2 9.1 12.3 3.6 7.5 1.9 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EFI27708.1 - 5 7.0 12.2 0.13 12.1 1.7 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zinc_ribbon_2 PF13240.6 EFI27708.1 - 6.3 6.7 7.8 1.5 8.6 1.6 3.0 3 1 0 3 3 3 0 zinc-ribbon domain PG_binding_1 PF01471.18 EFI27709.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain WD40 PF00400.32 EFI27711.1 - 1.2e-15 57.6 6.3 6.8e-07 29.9 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat RPN2_C PF18004.1 EFI27711.1 - 0.00089 19.2 1.5 0.0014 18.6 1.5 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain ANAPC4_WD40 PF12894.7 EFI27711.1 - 0.002 18.4 0.0 0.012 15.8 0.0 2.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 EFI27711.1 - 0.28 10.9 14.0 0.45 10.2 14.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 EFI27711.1 - 0.79 9.3 10.3 1.2 8.6 10.3 1.3 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EFI27711.1 - 2.1 7.6 12.2 2.3 7.4 10.7 1.7 2 0 0 2 2 2 0 NOA36 protein Pkinase PF00069.25 EFI27713.1 - 2.4e-77 259.9 0.0 2.9e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27713.1 - 6.4e-39 133.8 0.0 9.4e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EFI27713.1 - 3.8e-07 29.7 0.0 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EFI27713.1 - 9.5e-05 21.5 0.1 0.0003 19.8 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EFI27713.1 - 0.0062 15.9 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EFI27713.1 - 0.01 14.6 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Bromodomain PF00439.25 EFI27714.1 - 1.1e-20 73.5 0.0 2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3336 PF11815.8 EFI27715.1 - 3.1e-54 182.4 0.6 5.1e-54 181.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EFI27715.1 - 4.5e-18 66.2 0.1 9.5e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PUB PF09409.10 EFI27716.1 - 0.13 12.2 0.2 0.25 11.3 0.2 1.4 1 0 0 1 1 1 0 PUB domain WH2 PF02205.20 EFI27717.1 - 4.3e-09 35.9 1.6 1.3e-08 34.4 0.9 2.1 2 0 0 2 2 2 1 WH2 motif Gln-synt_C PF00120.24 EFI27718.1 - 2.2e-18 66.4 0.0 1.6e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EFI27718.1 - 5.9e-12 45.2 0.0 9.8e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Dcc1 PF09724.9 EFI27719.1 - 1.4e-85 287.6 0.4 1.6e-85 287.4 0.4 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DciA PF05258.12 EFI27719.1 - 0.14 12.6 0.0 0.7 10.3 0.0 2.1 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA Mito_carr PF00153.27 EFI27720.1 - 4.3e-61 202.9 2.2 3.8e-21 74.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EFI27720.1 - 0.0005 19.4 1.5 0.0019 17.6 0.6 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EFI27720.1 - 0.0014 18.4 1.2 0.007 16.2 1.2 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EFI27720.1 - 0.0018 18.7 1.9 0.0018 18.7 1.9 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EFI27720.1 - 0.0022 17.4 1.2 0.0022 17.4 1.2 2.4 2 0 0 2 2 2 1 EF hand Apt1 PF10351.9 EFI27721.1 - 8e-75 252.5 0.2 8e-75 252.5 0.2 1.6 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EFI27721.1 - 2e-51 175.4 0.0 2e-50 172.0 0.0 2.1 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EFI27721.1 - 2.1e-37 128.6 0.1 4e-37 127.7 0.1 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EFI27721.1 - 3.1e-28 98.6 0.0 2.9e-27 95.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EFI27721.1 - 9.8e-22 77.6 0.0 7.1e-21 74.9 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain PIN_4 PF13638.6 EFI27722.1 - 1.2e-20 74.1 0.0 2.1e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 PIN domain PIN PF01850.21 EFI27722.1 - 0.069 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 PIN domain DUF2985 PF11204.8 EFI27723.1 - 1.1e-24 86.4 0.9 1.7e-24 85.7 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) CTD_bind PF04818.13 EFI27724.1 - 4e-06 27.5 0.0 1.1e-05 26.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.6 EFI27724.1 - 1.1 10.3 6.5 8.8 7.5 0.2 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger FAD_binding_7 PF03441.14 EFI27726.1 - 2.2e-66 223.2 0.2 4.5e-66 222.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EFI27726.1 - 1.8e-33 115.9 0.0 3.2e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Herpes_UL49_5 PF05702.11 EFI27728.1 - 0.08 13.0 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein DUF2370 PF10176.9 EFI27730.1 - 7.4e-73 244.9 0.0 1.5e-72 243.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Acetyltransf_1 PF00583.25 EFI27731.1 - 7.8e-12 45.5 0.0 1.3e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EFI27731.1 - 1.1e-07 32.1 0.1 7.3e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EFI27731.1 - 9.4e-07 28.8 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EFI27731.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EFI27731.1 - 0.00086 20.0 0.0 0.002 18.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EFI27731.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase WW PF00397.26 EFI27732.1 - 0.0029 17.7 0.1 0.0029 17.7 0.1 2.2 2 0 0 2 2 2 1 WW domain DUF1919 PF08942.10 EFI27732.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) DUF952 PF06108.12 EFI27733.1 - 8.9e-21 73.7 0.0 1.4e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF952) UbiA PF01040.18 EFI27734.1 - 3.1e-52 177.4 12.5 5.6e-52 176.6 12.2 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family Rho_GDI PF02115.17 EFI27735.1 - 8.7e-55 185.5 0.0 1.1e-54 185.2 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Adap_comp_sub PF00928.21 EFI27737.1 - 2.9e-56 190.8 0.0 4.2e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EFI27737.1 - 0.00021 21.2 0.1 0.00038 20.4 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EFI27737.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain MS_channel PF00924.18 EFI27738.1 - 1.3e-14 54.3 0.2 2e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EI24 PF07264.11 EFI27738.1 - 0.00086 19.6 6.4 0.00086 19.6 6.4 2.2 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) EF-hand_7 PF13499.6 EFI27738.1 - 0.073 13.5 0.1 0.21 12.0 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EFI27738.1 - 0.091 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EFI27738.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 EF hand C2 PF00168.30 EFI27740.1 - 8.2e-15 55.0 0.0 7.4e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain Inh PF02974.14 EFI27742.1 - 0.032 14.3 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Protease inhibitor Inh Pkinase PF00069.25 EFI27744.1 - 1.7e-70 237.4 0.0 2.5e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27744.1 - 3.9e-32 111.5 0.0 6.3e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EFI27744.1 - 0.0052 16.1 1.4 5 6.3 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EFI27744.1 - 0.033 12.9 0.0 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF3501 PF12007.8 EFI27744.1 - 0.17 11.9 0.2 0.29 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) AMMECR1 PF01871.17 EFI27745.1 - 2.4e-46 157.4 0.0 3.5e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Ribosomal_S7e PF01251.18 EFI27746.1 - 6.1e-87 290.1 3.9 1.3e-86 289.1 3.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_1 PF00515.28 EFI27746.1 - 4.8e-10 38.8 6.1 0.00018 21.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EFI27746.1 - 3.6e-06 26.7 4.3 0.023 14.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EFI27746.1 - 0.00042 20.3 0.5 0.11 12.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EFI27746.1 - 0.0032 17.9 0.9 1.7 9.2 1.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EFI27746.1 - 0.006 16.2 0.9 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EFI27746.1 - 0.069 13.8 0.2 14 6.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EFI27746.1 - 0.17 12.1 3.8 0.77 10.0 3.7 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 GTP_cyclohydroI PF01227.22 EFI27749.1 - 7.2e-64 214.5 0.0 9.3e-64 214.1 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EFI27749.1 - 0.0011 19.1 0.0 0.0077 16.4 0.0 2.1 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 EFI27749.1 - 0.064 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain THOC2_N PF16134.5 EFI27750.1 - 4.4e-148 494.7 0.0 4.4e-148 494.7 0.0 2.5 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EFI27750.1 - 2.4e-71 240.4 0.0 6.1e-71 239.1 0.0 1.8 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EFI27750.1 - 3.8e-28 97.4 0.0 1.1e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Glyco_hydro_3_C PF01915.22 EFI27751.1 - 4e-61 206.5 0.0 3.5e-60 203.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EFI27751.1 - 6.9e-37 127.5 0.0 1.2e-36 126.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EFI27751.1 - 5.1e-21 74.6 2.1 8.1e-21 73.9 1.0 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EFI27751.1 - 0.00014 21.7 0.0 0.00033 20.5 0.0 1.6 1 0 0 1 1 1 1 PA14 domain fn3 PF00041.21 EFI27751.1 - 0.025 14.9 0.0 0.24 11.7 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III domain CARDB PF07705.11 EFI27751.1 - 0.073 13.3 0.1 0.98 9.7 0.0 2.5 2 0 0 2 2 2 0 CARDB DUF5060 PF16586.5 EFI27751.1 - 0.12 12.8 0.0 1 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) MutL_C PF08676.11 EFI27752.1 - 8.2e-07 28.9 0.0 4.4e-05 23.3 0.0 3.2 1 1 0 1 1 1 1 MutL C terminal dimerisation domain TusA PF01206.17 EFI27752.1 - 0.13 12.1 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Sulfurtransferase TusA HATPase_c_3 PF13589.6 EFI27753.1 - 3e-08 33.6 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EFI27753.1 - 1.2e-05 25.8 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carboxyl_trans PF01039.22 EFI27754.1 - 1.4e-131 439.6 0.2 1.7e-131 439.3 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 EFI27754.1 - 0.14 11.4 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase SKN1 PF03935.15 EFI27755.1 - 4.5e-173 576.2 7.9 1.1e-166 555.1 7.7 3.0 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 EFI27755.1 - 0.00041 19.9 0.1 0.0028 17.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RhoGEF PF00621.20 EFI27757.1 - 1.2e-34 120.2 1.3 1.4e-34 119.9 0.1 1.7 2 0 0 2 2 2 1 RhoGEF domain DUF3496 PF12001.8 EFI27757.1 - 0.046 14.1 0.2 0.046 14.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) TBK1_CCD1 PF18394.1 EFI27757.1 - 0.097 12.2 3.0 0.23 11.0 3.0 1.6 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 YscO PF07321.12 EFI27757.1 - 6.3 6.7 16.6 0.24 11.3 6.5 2.7 2 0 0 2 2 2 0 Type III secretion protein YscO LMBR1 PF04791.16 EFI27757.1 - 6.9 5.4 5.9 13 4.6 5.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CxC6 PF18721.1 EFI27759.1 - 1.9e-23 82.5 2.2 4.6e-23 81.3 2.2 1.7 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases CxC5 PF18718.1 EFI27759.1 - 5.7e-21 74.8 0.3 1.3e-20 73.6 0.3 1.7 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases TOPRIM_C PF16898.5 EFI27759.1 - 0.18 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal associated domain of TOPRIM Hid1 PF12722.7 EFI27760.1 - 0.91 7.6 2.7 1.4 7.0 2.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoporin2 PF04096.14 EFI27761.1 - 1.8e-45 154.7 0.0 2.6e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EFI27761.1 - 1.5e-25 89.9 292.5 2.9e-08 34.4 41.2 10.4 5 2 5 10 10 10 7 Nucleoporin FG repeat region HIG_1_N PF04588.13 EFI27762.1 - 0.00069 19.8 0.7 0.00069 19.8 0.7 1.9 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF2162 PF09930.9 EFI27762.1 - 0.015 14.7 0.1 0.027 13.9 0.0 1.4 2 0 0 2 2 2 0 Predicted transporter (DUF2162) PGAP1 PF07819.13 EFI27764.1 - 8.9e-53 179.4 0.0 1.3e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EFI27764.1 - 2.7e-05 24.9 0.9 2.7e-05 24.9 0.9 2.7 3 1 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EFI27764.1 - 0.00075 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EFI27764.1 - 0.0021 17.8 0.2 0.012 15.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 EFI27764.1 - 0.0069 15.7 0.0 0.049 13.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EFI27764.1 - 0.0093 15.8 0.2 0.27 11.1 0.1 2.3 1 1 1 2 2 2 1 Lipase (class 3) Viral_Beta_CD PF04530.12 EFI27764.1 - 0.058 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Viral Beta C/D like family TFIIB PF00382.19 EFI27766.1 - 1.9e-35 120.8 0.1 4.3e-20 71.5 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EFI27766.1 - 7.9e-15 54.1 1.7 1.4e-14 53.3 1.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.15 EFI27766.1 - 0.0027 18.2 2.3 1.3 9.5 0.1 3.1 1 1 2 3 3 3 2 Guanylin precursor Cyclin_N PF00134.23 EFI27766.1 - 0.019 14.7 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain HTH_5 PF01022.20 EFI27766.1 - 0.054 13.4 0.0 14 5.6 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family RB_B PF01857.20 EFI27766.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 EFI27766.1 - 0.22 11.0 3.4 0.76 9.3 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Abhydrolase_1 PF00561.20 EFI27767.1 - 1.3e-27 97.0 0.0 1.3e-26 93.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EFI27767.1 - 2.7e-18 67.4 0.1 3.7e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EFI27767.1 - 5.7e-09 35.6 0.0 2.7e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 EFI27767.1 - 4.6e-07 28.8 0.0 9e-07 27.9 0.0 1.4 1 0 0 1 1 1 1 Ndr family DUF3530 PF12048.8 EFI27767.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) CDC14 PF08045.11 EFI27768.1 - 2.9e-29 102.1 0.1 3.5e-23 82.1 0.0 3.2 2 1 0 2 2 2 2 Cell division control protein 14, SIN component SesA PF17107.5 EFI27768.1 - 0.2 11.8 1.8 0.32 11.2 0.8 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Macoilin PF09726.9 EFI27768.1 - 4.5 5.7 5.7 6.2 5.3 5.7 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EFI27768.1 - 8.1 5.2 6.8 13 4.5 6.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain MRP-L47 PF06984.13 EFI27769.1 - 0.051 13.7 0.1 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) ACTL7A_N PF16840.5 EFI27771.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Actin-like protein 7A N-terminus Zn_clus PF00172.18 EFI27772.1 - 9.2e-06 25.7 2.7 1.5e-05 25.0 2.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pacs-1 PF10254.9 EFI27775.1 - 0.02 13.8 1.4 0.025 13.5 1.4 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein TIP120 PF08623.10 EFI27775.1 - 0.022 14.5 1.0 0.034 13.9 1.0 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Cytomega_UL84 PF06284.11 EFI27775.1 - 0.097 11.1 2.2 0.13 10.7 2.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CALM_bind PF16025.5 EFI27775.1 - 1.3 9.5 8.1 2.6 8.6 8.1 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding 2OG-FeII_Oxy_3 PF13640.6 EFI27778.1 - 2.1e-11 44.6 0.1 3.3e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EFI27778.1 - 0.05 13.8 0.1 0.52 10.5 0.1 2.5 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) AsnA PF03590.15 EFI27778.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Aspartate-ammonia ligase 2OG-FeII_Oxy_3 PF13640.6 EFI27779.1 - 1.5e-11 45.0 0.0 2.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EFI27779.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.4 1 1 0 1 1 1 0 Poxvirus C4/C10 protein GatB_N PF02934.15 EFI27780.1 - 2.5e-105 351.8 0.0 3.3e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EFI27780.1 - 5e-29 101.1 0.8 4.4e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 GatB domain DUF262 PF03235.14 EFI27781.1 - 1.8e-16 61.0 0.6 8.7e-16 58.8 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function DUF262 DUF4355 PF14265.6 EFI27781.1 - 0.0037 17.5 0.1 0.0069 16.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) 4HBT PF03061.22 EFI27782.1 - 7.1e-07 29.5 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EFI27782.1 - 0.0031 17.8 0.0 0.0063 16.8 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily F-box PF00646.33 EFI27784.1 - 0.031 14.1 0.1 0.084 12.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EFI27785.1 - 7.3e-22 77.0 19.9 1.4e-10 40.8 1.8 3.8 3 0 0 3 3 3 3 F-box-like LRR_8 PF13855.6 EFI27785.1 - 0.034 13.9 9.7 1.4 8.7 0.1 6.2 7 0 0 7 7 7 0 Leucine rich repeat CENP-B_dimeris PF09026.10 EFI27785.1 - 0.12 12.8 1.1 0.26 11.7 1.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Dicty_REP PF05086.12 EFI27786.1 - 4.5 5.1 11.2 6.6 4.6 11.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M24 PF00557.24 EFI27787.1 - 1.8e-50 171.6 0.0 2.1e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 MoCF_biosynth PF00994.24 EFI27789.1 - 2.3e-60 202.4 0.4 1.4e-29 102.7 0.2 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EFI27789.1 - 4.7e-38 130.4 0.6 7.3e-38 129.8 0.6 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EFI27789.1 - 6e-10 39.2 0.1 2.7e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) RasGAP PF00616.19 EFI27794.1 - 2e-18 66.9 0.0 9.1e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EFI27794.1 - 4.4e-06 26.9 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 EFI27794.1 - 0.00055 19.9 0.3 0.0037 17.2 0.1 2.5 3 0 0 3 3 3 1 Cell morphogenesis C-terminal F-box-like PF12937.7 EFI27799.1 - 4.6e-10 39.2 0.7 1.1e-09 38.1 0.4 1.8 2 0 0 2 2 2 1 F-box-like FlxA PF14282.6 EFI27799.1 - 0.021 14.8 0.2 0.033 14.2 0.2 1.2 1 0 0 1 1 1 0 FlxA-like protein DEAD PF00270.29 EFI27802.1 - 3.2e-17 62.8 0.0 1.1e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EFI27802.1 - 1.8e-11 44.4 0.0 4.9e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EFI27802.1 - 3.3e-07 30.6 0.1 1.5e-06 28.5 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain F-box-like PF12937.7 EFI27803.1 - 6.3e-07 29.2 2.5 7.7e-07 28.9 1.0 2.1 2 0 0 2 2 2 1 F-box-like DivIC PF04977.15 EFI27803.1 - 0.0011 18.6 1.0 0.0022 17.7 1.0 1.4 1 0 0 1 1 1 1 Septum formation initiator DUF3287 PF11690.8 EFI27803.1 - 0.086 12.6 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) MerR-DNA-bind PF09278.11 EFI27803.1 - 0.13 12.8 2.0 0.29 11.7 2.0 1.6 1 0 0 1 1 1 0 MerR, DNA binding DUF3810 PF12725.7 EFI27806.1 - 0.067 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) KDZ PF18758.1 EFI27810.1 - 1e-52 179.0 0.0 1.5e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase AT_hook PF02178.19 EFI27810.1 - 0.0044 16.7 23.5 0.21 11.6 6.6 3.2 2 0 0 2 2 2 2 AT hook motif ORC6 PF05460.13 EFI27810.1 - 2.3 7.4 8.9 3.7 6.7 8.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 EFI27810.1 - 8.6 4.9 7.8 12 4.4 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GATA PF00320.27 EFI27811.1 - 7.7e-13 47.8 3.6 7.7e-13 47.8 3.6 2.1 3 0 0 3 3 3 1 GATA zinc finger Coatomer_WDAD PF04053.14 EFI27813.1 - 1.3e-24 87.1 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region KfrA_N PF11740.8 EFI27813.1 - 0.1 13.2 1.8 0.16 12.6 1.8 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RNA_pol_3_Rpc31 PF11705.8 EFI27813.1 - 0.23 11.7 16.2 0.27 11.5 16.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 EFI27813.1 - 1.4 6.9 6.7 1.7 6.7 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cwf_Cwc_15 PF04889.12 EFI27813.1 - 1.6 8.4 16.7 2.1 8.0 16.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EFI27813.1 - 2.1 7.6 21.6 2.6 7.3 21.6 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EFI27813.1 - 2.7 7.0 27.0 3.1 6.8 27.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Coatomer_WDAD PF04053.14 EFI27814.1 - 3e-06 26.6 0.0 3.4e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Coatomer WD associated region DUF4401 PF14351.6 EFI27815.1 - 0.00032 20.1 0.3 0.00038 19.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) AAA_16 PF13191.6 EFI27817.1 - 0.00026 21.4 0.1 0.00094 19.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EFI27817.1 - 0.00036 20.5 0.0 0.64 9.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EFI27817.1 - 0.014 15.7 0.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EFI27817.1 - 0.016 15.6 0.0 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EFI27817.1 - 0.035 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 EFI27817.1 - 0.2 12.0 0.0 0.55 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF1996 PF09362.10 EFI27818.1 - 1.2e-65 221.9 0.1 1.6e-65 221.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) JAB PF01398.21 EFI27819.1 - 2.9e-11 43.4 0.1 3.4e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EFI27819.1 - 0.019 14.7 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DUF3081 PF11280.8 EFI27819.1 - 0.059 13.2 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) Aldo_ket_red PF00248.21 EFI27822.1 - 2.4e-61 207.5 0.0 3.9e-61 206.8 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_S9 PF00326.21 EFI27825.1 - 6.8e-39 133.5 0.0 9.3e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EFI27825.1 - 3.5e-08 33.0 0.0 3.3e-06 26.5 0.0 2.1 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EFI27825.1 - 2e-06 27.7 0.7 0.06 13.0 0.4 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 EFI27825.1 - 4.8e-06 26.3 0.0 8.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 EFI27825.1 - 1.2e-05 24.2 0.2 0.001 17.8 0.2 2.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EFI27825.1 - 0.00015 21.7 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EFI27825.1 - 0.00025 21.0 0.0 0.0008 19.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EFI27825.1 - 0.0024 16.8 0.1 0.0039 16.1 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family FSH1 PF03959.13 EFI27825.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EFI27825.1 - 0.0035 17.3 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PQQ_3 PF13570.6 EFI27825.1 - 0.006 17.0 0.6 0.038 14.5 0.1 2.7 2 0 0 2 2 2 1 PQQ-like domain Peptidase_S15 PF02129.18 EFI27825.1 - 0.049 13.2 0.0 0.48 10.0 0.0 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) MFS_1 PF07690.16 EFI27826.1 - 6.3e-25 87.8 24.2 1.5e-24 86.6 24.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase_fungal PF17667.1 EFI27827.1 - 1e-88 297.9 0.0 2.2e-48 165.1 0.0 2.5 2 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EFI27827.1 - 1.4e-15 57.4 0.0 3.3e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27827.1 - 9.4e-05 21.8 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EFI27827.1 - 0.00055 19.9 0.1 0.17 11.8 0.1 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Cu-oxidase_3 PF07732.15 EFI27827.1 - 0.26 11.3 0.4 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Multicopper oxidase Pkinase_fungal PF17667.1 EFI27828.1 - 1.9e-49 168.6 0.0 2.9e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EFI27828.1 - 2.4e-06 27.1 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI27828.1 - 0.054 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase F-box-like PF12937.7 EFI27829.1 - 6.9e-06 25.9 2.7 1.6e-05 24.7 2.7 1.7 1 0 0 1 1 1 1 F-box-like DUF4795 PF16043.5 EFI27829.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 EFI27829.1 - 0.032 14.5 0.2 0.062 13.6 0.2 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 EFI27829.1 - 0.074 13.3 0.4 0.14 12.4 0.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF5082 PF16888.5 EFI27829.1 - 0.11 12.8 1.8 0.2 12.0 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Spc24 PF08286.11 EFI27829.1 - 0.16 12.3 0.6 0.27 11.5 0.6 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3450 PF11932.8 EFI27829.1 - 0.19 11.0 0.2 0.3 10.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 EFI27829.1 - 0.2 10.6 0.1 0.32 9.9 0.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1241 PF06840.11 EFI27829.1 - 0.38 10.4 0.9 0.56 9.8 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) SPK PF04435.18 EFI27830.1 - 0.042 14.2 0.1 0.063 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF545) DUF730 PF05325.11 EFI27830.1 - 0.062 13.3 0.0 0.079 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF730) DUF21 PF01595.20 EFI27832.1 - 4.4e-30 104.7 0.2 6.3e-30 104.2 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain WD40 PF00400.32 EFI27834.1 - 4.3e-43 144.5 18.8 4.9e-08 33.5 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EFI27834.1 - 0.00042 20.6 0.6 0.73 10.2 0.1 4.2 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EFI27834.1 - 0.0057 15.4 0.9 3.7 6.1 0.1 3.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EFI27834.1 - 0.084 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain LRR_4 PF12799.7 EFI27836.1 - 0.097 13.1 0.1 0.097 13.1 0.1 3.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) PCNA_N PF00705.18 EFI27836.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain TPR_8 PF13181.6 EFI27841.1 - 7.6e-12 44.5 1.6 0.00038 20.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EFI27841.1 - 7.3e-11 42.0 12.8 0.00015 22.3 0.1 4.9 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EFI27841.1 - 2.8e-09 36.4 9.0 0.0002 21.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EFI27841.1 - 1.4e-06 27.9 7.4 0.00083 19.1 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EFI27841.1 - 7.6e-06 26.4 2.0 0.0002 21.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EFI27841.1 - 0.00029 21.0 1.6 0.0035 17.5 0.1 2.6 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EFI27841.1 - 0.00045 19.8 1.4 0.0032 17.1 0.2 2.7 2 0 0 2 2 2 1 TPR repeat TPR_15 PF13429.6 EFI27841.1 - 0.00084 18.6 0.3 0.13 11.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EFI27841.1 - 0.018 15.0 0.6 0.32 11.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EFI27841.1 - 0.025 14.7 1.0 0.073 13.2 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EFI27841.1 - 0.033 14.6 0.6 9.4 6.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EFI27841.1 - 0.056 14.1 0.3 0.056 14.1 0.3 4.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EFI27841.1 - 0.66 10.3 10.0 2.6 8.4 1.4 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EFI27841.1 - 0.89 10.3 15.4 0.21 12.2 0.4 3.9 4 1 1 5 5 4 0 Tetratricopeptide repeat Peptidase_M24 PF00557.24 EFI27842.1 - 5.2e-57 192.9 0.0 6.8e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EFI27842.1 - 9.6e-19 67.3 0.0 1.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain U71 PF17474.2 EFI27844.1 - 0.00065 19.6 0.2 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 Tegument protein UL11 homolog MTHFR_C PF12225.8 EFI27844.1 - 0.2 11.3 5.0 0.96 9.1 0.8 2.5 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal DUF5384 PF17358.2 EFI27844.1 - 0.26 11.3 10.9 0.66 10.0 10.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5384) Fer4_2 PF12797.7 EFI27844.1 - 3.1 8.1 9.1 6.5 7.1 2.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain CIAPIN1 PF05093.13 EFI27844.1 - 9.3 6.8 8.8 2.1 8.9 0.1 3.2 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MatP_C PF17414.2 EFI27845.1 - 0.033 14.4 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain CCDC106 PF15794.5 EFI27846.1 - 0.12 12.1 7.3 0.24 11.1 7.3 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF4509 PF14970.6 EFI27846.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Spc7 PF08317.11 EFI27846.1 - 0.32 9.8 2.4 0.66 8.8 2.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 EFI27846.1 - 0.75 9.1 6.0 2.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TFIIE-A_C PF11521.8 EFI27846.1 - 5.4 7.4 20.1 1.5 9.1 0.4 3.8 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha IL12p40_C PF10420.9 EFI27850.1 - 0.48 11.0 4.2 15 6.2 0.6 2.8 2 1 1 3 3 3 0 Cytokine interleukin-12p40 C-terminus DUF883 PF05957.13 EFI27851.1 - 0.064 13.9 0.2 0.091 13.4 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) UPF0561 PF10573.9 EFI27853.1 - 0.15 12.2 2.0 0.18 11.9 1.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 p450 PF00067.22 EFI27854.1 - 1.4e-29 103.2 0.0 2.3e-19 69.5 0.0 3.4 2 2 0 2 2 2 2 Cytochrome P450 ESSS PF10183.9 EFI27859.1 - 0.043 14.0 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) IL34 PF15036.6 EFI27861.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Interleukin 34 Syntaxin_2 PF14523.6 EFI27861.1 - 0.14 12.6 0.0 14 6.1 0.0 2.7 2 1 0 2 2 2 0 Syntaxin-like protein AT_hook PF02178.19 EFI27862.1 - 0.0054 16.5 0.7 0.0054 16.5 0.7 2.0 2 0 0 2 2 2 1 AT hook motif KDZ PF18758.1 EFI27864.1 - 3.5e-38 131.5 0.1 8.7e-38 130.1 0.1 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase HA PF03457.14 EFI27864.1 - 0.12 12.7 0.6 0.32 11.4 0.6 1.7 1 0 0 1 1 1 0 Helicase associated domain DivIC PF04977.15 EFI27864.1 - 0.27 11.0 2.3 0.31 10.8 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.7 EFI27865.1 - 9.9e-07 28.6 0.4 3.4e-06 26.8 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EFI27865.1 - 0.093 12.6 0.3 2.1 8.3 0.0 3.3 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.7 EFI27866.1 - 0.0026 17.6 0.2 0.0068 16.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like Cpn60_TCP1 PF00118.24 EFI27869.1 - 1e-155 519.2 1.7 1.1e-155 519.0 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Metallophos PF00149.28 EFI27870.1 - 3.9e-36 125.5 0.6 5.4e-36 125.0 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EFI27870.1 - 0.00012 22.4 0.1 0.00025 21.4 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EFI27870.1 - 0.014 15.1 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TRAP-gamma PF07074.12 EFI27871.1 - 0.28 10.7 1.5 0.5 9.9 1.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) CRAL_TRIO PF00650.20 EFI27874.1 - 3.3e-23 82.2 0.0 6.2e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EFI27874.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Abhydrolase_1 PF00561.20 EFI27876.1 - 2e-38 132.5 0.0 2.5e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EFI27876.1 - 4.4e-13 49.1 0.0 1.4e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EFI27876.1 - 1.6e-09 38.7 0.0 2.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EFI27876.1 - 0.038 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 EFI27876.1 - 0.08 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.12 EFI27876.1 - 0.096 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Sad1_UNC PF07738.13 EFI27877.1 - 4.8e-25 88.1 0.0 3.6e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DUF2408 PF10303.9 EFI27877.1 - 0.038 14.6 0.2 0.086 13.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DivIC PF04977.15 EFI27877.1 - 0.041 13.7 0.9 0.12 12.1 0.9 1.8 1 0 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 EFI27877.1 - 0.59 9.0 3.4 0.97 8.2 3.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Vma12 PF11712.8 EFI27878.1 - 0.28 11.2 1.8 1.7 8.7 0.7 2.4 2 1 1 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF5391 PF17369.2 EFI27878.1 - 1.8 8.6 10.7 5.2 7.1 10.7 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5391) eIF-5_eIF-2B PF01873.17 EFI27879.1 - 1.5e-39 134.5 0.4 2.9e-39 133.6 0.1 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 EFI27879.1 - 2.7e-25 88.3 0.1 1.2e-24 86.2 0.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon UME PF08064.13 EFI27879.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 UME (NUC010) domain NUDIX PF00293.28 EFI27880.1 - 3.5e-15 56.2 0.3 4.1e-15 56.0 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain zf-C2H2 PF00096.26 EFI27882.1 - 5.9e-07 29.6 9.3 8.3e-05 22.8 1.4 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EFI27882.1 - 0.00069 20.3 8.7 0.036 14.9 1.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EFI27882.1 - 0.0029 17.3 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EFI27882.1 - 0.0063 16.5 0.5 0.014 15.4 0.5 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf_UBZ PF18439.1 EFI27882.1 - 0.032 13.8 0.3 0.07 12.7 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 EFI27882.1 - 0.034 14.6 7.9 0.48 11.0 2.7 3.3 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 EFI27882.1 - 0.055 14.1 4.5 10 6.9 0.1 3.2 1 1 2 3 3 3 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 EFI27882.1 - 0.23 11.1 2.4 1.5 8.5 0.1 2.6 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Inhibitor_I67 PF11405.8 EFI27882.1 - 3.3 8.1 7.2 7.7 6.9 0.6 2.8 3 0 0 3 3 3 0 Bromelain inhibitor VI NPR3 PF03666.13 EFI27887.1 - 5.3e-105 351.9 0.0 5.3e-105 351.9 0.0 1.8 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Ras PF00071.22 EFI27889.1 - 2.1e-47 160.7 0.0 2.5e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EFI27889.1 - 4.1e-18 65.7 0.0 6.2e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EFI27889.1 - 4.3e-06 26.7 0.4 0.0047 16.8 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 EFI27889.1 - 1.9e-05 24.2 0.1 2.2e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EFI27889.1 - 0.00019 21.5 0.1 0.00034 20.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EFI27889.1 - 0.00059 19.4 0.1 0.0018 17.9 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KTI12 PF08433.10 EFI27889.1 - 0.038 13.5 0.6 0.24 10.8 0.1 2.3 2 1 1 3 3 3 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EFI27889.1 - 0.091 13.1 0.6 0.23 11.8 0.6 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EFI27889.1 - 0.11 12.8 0.1 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EFI27889.1 - 0.12 12.0 0.4 0.29 10.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 EFI27890.1 - 6.5e-53 179.1 0.0 8.4e-52 175.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EFI27890.1 - 4.9e-15 55.8 0.0 1.1e-13 51.5 0.0 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EFI27890.1 - 3.4e-07 30.4 0.0 1.3e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.29 EFI27890.1 - 0.023 15.1 0.0 4 7.9 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EFI27890.1 - 0.07 13.5 0.0 11 6.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EFI27890.1 - 0.24 11.7 0.4 2.7 8.2 0.4 2.3 1 1 0 1 1 1 0 AAA domain Hydrolase_4 PF12146.8 EFI27891.1 - 1.6e-06 27.5 0.0 0.0014 17.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Helicase_C PF00271.31 EFI27891.1 - 4.7e-05 23.7 0.0 8.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_S9 PF00326.21 EFI27891.1 - 5.2e-05 22.8 0.0 9.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EFI27891.1 - 0.0043 16.7 0.6 1.3 8.6 0.0 2.4 3 0 0 3 3 3 2 alpha/beta hydrolase fold PhoPQ_related PF10142.9 EFI27891.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Keratin_2_head PF16208.5 EFI27891.1 - 2.2 8.4 30.7 4.5 7.4 30.7 1.5 1 0 0 1 1 1 0 Keratin type II head MARVEL PF01284.23 EFI27892.1 - 4.6e-09 36.5 7.3 6.8e-09 35.9 7.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain Podoplanin PF05808.11 EFI27893.1 - 0.016 15.3 3.3 0.029 14.5 3.3 1.4 1 0 0 1 1 1 0 Podoplanin VSP PF03302.13 EFI27893.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4366 PF14283.6 EFI27893.1 - 0.23 11.5 2.0 0.44 10.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) zf-CCHC PF00098.23 EFI27894.1 - 0.034 14.2 3.9 0.034 14.2 3.9 2.8 1 1 2 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.6 EFI27894.1 - 0.039 13.8 0.6 0.039 13.8 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle Zn-ribbon_8 PF09723.10 EFI27894.1 - 0.19 11.9 3.5 1.4 9.1 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 EFI27894.1 - 0.41 10.6 8.9 0.46 10.4 0.3 2.6 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Desulfoferrod_N PF06397.12 EFI27894.1 - 0.52 10.0 4.5 1.9 8.2 0.4 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-CCHC_2 PF13696.6 EFI27894.1 - 0.82 9.6 14.1 2.4 8.1 2.9 3.2 2 2 0 2 2 2 0 Zinc knuckle HypA PF01155.19 EFI27894.1 - 0.93 9.5 2.9 1.3 9.0 2.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CCHC_3 PF13917.6 EFI27894.1 - 0.95 9.5 12.0 3.7 7.6 12.0 2.0 1 1 0 1 1 1 0 Zinc knuckle YhfH PF14149.6 EFI27894.1 - 1.6 8.7 5.8 2.9 8.0 5.8 1.4 1 0 0 1 1 1 0 YhfH-like protein Dimer_Tnp_hAT PF05699.14 EFI27895.1 - 0.034 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region RepB-RCR_reg PF10723.9 EFI27895.1 - 0.046 13.7 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Replication regulatory protein RepB DUF4413 PF14372.6 EFI27895.1 - 0.16 12.4 0.1 0.47 10.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) PDZ_4 PF17816.1 EFI27895.1 - 0.17 12.3 0.0 24 5.3 0.0 2.4 2 0 0 2 2 2 0 PDZ domain GCIP PF13324.6 EFI27895.1 - 0.48 10.0 2.3 1.5 8.4 2.3 1.8 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 EFI27895.1 - 5.4 6.7 10.4 13 5.4 10.4 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Complex1_LYR PF05347.15 EFI27898.1 - 1.3e-10 41.2 0.8 1.3e-10 41.2 0.8 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EFI27898.1 - 0.0027 18.4 1.7 0.0035 18.0 1.7 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_31 PF13847.6 EFI27899.1 - 3.2e-10 40.0 0.0 8.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EFI27899.1 - 0.0025 18.5 0.1 0.02 15.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EFI27899.1 - 0.01 16.4 0.1 2.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EFI27899.1 - 0.03 15.1 0.2 0.15 12.8 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain DUF1422 PF07226.11 EFI27899.1 - 0.2 11.7 0.0 0.45 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Aconitase PF00330.20 EFI27900.1 - 1.4e-109 367.2 0.0 1.2e-108 364.1 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EFI27900.1 - 9.9e-20 71.2 0.1 2.8e-19 69.8 0.1 1.8 1 1 0 1 1 1 1 Aconitase C-terminal domain GGACT PF06094.12 EFI27900.1 - 1.8e-09 38.2 0.0 4.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF2616 PF11077.8 EFI27902.1 - 0.003 17.3 0.5 0.0051 16.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2616) Coatomer_E PF04733.14 EFI27902.1 - 0.0078 15.7 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit CTU2 PF10288.9 EFI27902.1 - 0.0088 16.3 2.0 0.32 11.2 0.0 2.8 2 1 1 3 3 3 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_3 PF13920.6 EFI27902.1 - 0.041 13.8 4.6 0.042 13.7 1.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 EFI27902.1 - 0.066 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain DZR PF12773.7 EFI27902.1 - 2 8.5 6.2 41 4.3 0.0 2.8 2 1 1 3 3 3 0 Double zinc ribbon adh_short PF00106.25 EFI27903.1 - 1.3e-14 54.1 0.0 1.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EFI27903.1 - 1.3e-10 41.4 0.1 1.8e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EFI27903.1 - 1.6e-09 37.7 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EFI27903.1 - 0.00011 22.2 0.1 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EFI27903.1 - 0.00051 19.6 0.0 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EFI27903.1 - 0.0071 15.9 0.1 0.0089 15.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EFI27903.1 - 0.025 13.7 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EFI27903.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Meth_synt_2 PF01717.18 EFI27903.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain UvrD-helicase PF00580.21 EFI27904.1 - 3.4e-61 207.5 0.2 1.7e-60 205.2 0.0 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EFI27904.1 - 6.5e-60 203.4 0.1 1.3e-59 202.3 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EFI27904.1 - 2.7e-32 112.1 0.0 6.6e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EFI27904.1 - 5.2e-14 51.8 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EFI27904.1 - 1.3e-10 41.4 0.3 0.0023 17.7 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EFI27904.1 - 0.00086 19.0 0.2 0.0085 15.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EFI27904.1 - 0.0011 18.8 0.1 0.03 14.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EFI27904.1 - 0.0011 18.8 2.8 0.0018 18.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain DDE_Tnp_IS66 PF03050.14 EFI27904.1 - 0.015 14.8 0.8 8 5.8 0.5 3.1 3 0 0 3 3 3 0 Transposase IS66 family OPT PF03169.15 EFI27905.1 - 1.4e-139 466.6 18.8 1.6e-139 466.4 18.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 EFI27905.1 - 0.74 9.9 3.6 17 5.5 0.4 3.3 2 0 0 2 2 2 0 Bacteriophage P21 holin S SARAF PF06682.12 EFI27906.1 - 1.1e-68 232.4 0.0 1.3e-68 232.2 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4678 PF15727.5 EFI27907.1 - 0.00097 18.5 1.1 0.0012 18.3 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4678) Citrate_synt PF00285.21 EFI27910.1 - 2.8e-83 280.0 0.0 3.1e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sugar_tr PF00083.24 EFI27912.1 - 3.4e-39 135.0 28.1 9.9e-23 80.7 10.2 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EFI27912.1 - 2e-17 63.1 44.5 8.9e-13 47.9 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1182 PF06681.13 EFI27912.1 - 0.75 9.3 5.9 0.55 9.8 0.1 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1182) Transgly_assoc PF04226.13 EFI27912.1 - 4.1 7.7 11.8 0.24 11.7 1.5 3.7 3 0 0 3 3 3 0 Transglycosylase associated protein WD40 PF00400.32 EFI27913.1 - 9.7e-13 48.4 6.1 0.028 15.3 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat PriCT_1 PF08708.11 EFI27916.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Pox_Ag35 PF03286.14 EFI27918.1 - 2.2 8.0 13.1 3.8 7.3 13.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 EFI27918.1 - 2.6 6.1 10.6 3.7 5.6 10.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EFI27918.1 - 2.9 6.1 7.3 3.7 5.7 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 EFI27918.1 - 7.1 6.0 9.0 9.6 5.5 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_C14 PF00656.22 EFI27919.1 - 4.4e-22 79.2 0.0 6.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain CHAT PF12770.7 EFI27919.1 - 0.17 11.2 0.0 0.36 10.2 0.0 1.5 1 1 0 1 1 1 0 CHAT domain Peptidase_C14 PF00656.22 EFI27920.1 - 1.1e-10 42.0 0.0 1.8e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain ThiS PF02597.20 EFI27921.1 - 3.9e-05 24.2 0.0 4.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 ThiS family PRMT5 PF05185.16 EFI27922.1 - 4.5e-65 218.7 0.0 7.4e-65 218.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EFI27922.1 - 1.9e-60 204.3 0.3 1.2e-58 198.4 0.3 2.2 1 1 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EFI27922.1 - 8.7e-51 172.3 0.3 1.8e-50 171.3 0.3 1.5 1 1 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 EFI27922.1 - 0.00032 21.4 0.0 0.00073 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EFI27922.1 - 0.019 15.6 0.0 0.046 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SWI-SNF_Ssr4 PF08549.10 EFI27923.1 - 0.075 11.7 1.7 0.083 11.5 1.7 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3617 PF12276.8 EFI27923.1 - 0.13 12.6 1.1 0.17 12.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Adeno_PX PF05829.12 EFI27923.1 - 1.4 8.8 11.6 0.47 10.4 6.5 2.6 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) DUF4112 PF13430.6 EFI27926.1 - 1.2e-34 118.7 0.2 1.6e-34 118.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) APG17 PF04108.12 EFI27927.1 - 6.6e-74 249.4 22.2 2.7e-73 247.4 22.2 1.7 1 1 0 1 1 1 1 Autophagy protein Apg17 FAST_2 PF08368.12 EFI27927.1 - 0.038 14.8 0.3 0.2 12.4 0.1 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 DUF1664 PF07889.12 EFI27927.1 - 0.15 12.1 13.1 1.2 9.2 0.6 4.4 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) ExsD PF16806.5 EFI27927.1 - 0.27 11.1 6.1 0.17 11.8 0.6 2.7 1 1 2 3 3 3 0 Antiactivator protein ExsD DinB_2 PF12867.7 EFI27927.1 - 0.3 11.6 3.2 4.8 7.7 0.3 3.1 2 1 1 3 3 3 0 DinB superfamily Spectrin_like PF18373.1 EFI27927.1 - 0.34 11.0 7.1 4.3 7.5 0.0 3.7 4 1 0 4 4 4 0 Spectrin like domain Spc7 PF08317.11 EFI27927.1 - 0.52 9.1 19.0 1.9 7.3 2.2 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TBCC_N PF16752.5 EFI27927.1 - 0.81 10.1 12.3 1.6 9.2 2.6 3.5 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain HalX PF08663.10 EFI27927.1 - 1.1 9.7 11.4 3.1 8.2 1.8 3.5 2 0 0 2 2 2 0 HalX domain GIT_CC PF16559.5 EFI27927.1 - 1.3 9.0 6.1 4.8 7.1 0.6 3.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TINF2_N PF14973.6 EFI27927.1 - 1.3 9.3 6.3 0.38 11.1 1.0 2.6 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus DUF885 PF05960.11 EFI27927.1 - 3.5 7.2 14.0 1.9 8.0 12.1 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Nsp1_C PF05064.13 EFI27927.1 - 4.8 7.0 10.9 9.1 6.1 0.4 4.2 4 0 0 4 4 4 0 Nsp1-like C-terminal region Snapin_Pallidin PF14712.6 EFI27927.1 - 6.4 7.3 9.9 23 5.5 0.6 4.1 3 1 1 4 4 4 0 Snapin/Pallidin DUF4047 PF13256.6 EFI27927.1 - 7.3 6.8 6.7 11 6.2 0.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) RasGAP_C PF03836.15 EFI27927.1 - 9 6.4 14.4 4.6 7.4 0.9 4.1 4 1 0 4 4 4 0 RasGAP C-terminus MOZ_SAS PF01853.18 EFI27928.1 - 9.7e-74 246.9 0.0 1.5e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EFI27928.1 - 1.2e-20 72.9 0.2 2.9e-20 71.6 0.2 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain PHD PF00628.29 EFI27928.1 - 8.8e-15 54.3 21.6 6.7e-10 38.7 1.9 3.6 3 1 1 4 4 4 2 PHD-finger Methyltransf_32 PF13679.6 EFI27928.1 - 2e-14 53.9 0.0 4.6e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PHD_4 PF16866.5 EFI27928.1 - 4.3e-05 23.5 15.9 0.052 13.7 4.2 2.6 1 1 1 2 2 2 2 PHD-finger Methyltransf_31 PF13847.6 EFI27928.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EFI27928.1 - 0.02 15.6 0.0 0.046 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EFI27928.1 - 0.025 15.3 0.0 0.062 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EFI27928.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RSN1_7TM PF02714.15 EFI27929.1 - 1.6e-82 276.9 21.4 2.5e-82 276.3 21.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EFI27929.1 - 7.7e-36 123.2 0.5 2.1e-35 121.8 0.5 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EFI27929.1 - 3.7e-35 121.7 0.1 1e-25 90.9 0.0 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EFI27929.1 - 4.5e-13 49.2 0.1 9.7e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF3040 PF11239.8 EFI27930.1 - 5.6 7.3 5.7 75 3.7 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3040) HATPase_c PF02518.26 EFI27931.1 - 9.6e-21 74.4 0.0 2.8e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EFI27931.1 - 1.6e-19 70.1 0.0 3.4e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EFI27931.1 - 6.1e-14 51.8 0.0 1.7e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 EFI27931.1 - 0.0065 16.8 0.0 4.6 7.6 0.0 2.9 2 0 0 2 2 2 2 GAF domain DUF1966 PF09260.11 EFI27931.1 - 0.14 12.5 0.1 0.46 10.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) DUF1115 PF06544.12 EFI27932.1 - 0.00013 22.1 0.0 0.0002 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Ferric_reduct PF01794.19 EFI27933.1 - 8.4e-19 67.9 13.3 8.4e-19 67.9 13.3 1.8 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EFI27933.1 - 0.00068 19.7 0.5 0.0024 17.9 0.0 2.1 3 0 0 3 3 3 1 FAD-binding domain NAD_binding_6 PF08030.12 EFI27933.1 - 0.073 13.2 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF2427 PF10348.9 EFI27933.1 - 0.6 9.9 8.4 0.028 14.2 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) PFK PF00365.20 EFI27934.1 - 5.1e-183 606.8 0.5 7.2e-82 274.9 0.0 3.0 3 0 0 3 3 3 3 Phosphofructokinase DAGK_cat PF00781.24 EFI27934.1 - 0.077 12.6 0.3 0.29 10.7 0.1 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Yip1 PF04893.17 EFI27937.1 - 1.6e-13 50.7 15.8 2.5e-13 50.1 15.8 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EFI27937.1 - 0.027 14.3 10.1 0.039 13.7 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) ABC_tran PF00005.27 EFI27939.1 - 1.1e-37 129.6 0.1 4.7e-27 95.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EFI27939.1 - 3.5e-35 122.0 25.9 7.2e-19 68.5 1.8 3.3 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EFI27939.1 - 1.1e-06 28.2 0.7 0.00085 18.8 0.0 3.0 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EFI27939.1 - 0.0017 18.2 0.2 1.8 8.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EFI27939.1 - 0.0031 17.6 0.0 0.008 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EFI27939.1 - 0.019 15.3 0.2 0.16 12.3 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EFI27939.1 - 0.14 12.0 0.2 0.33 10.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Polysacc_deac_1 PF01522.21 EFI27941.1 - 1.1e-30 106.1 0.0 1.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DASH_Dad2 PF08654.10 EFI27941.1 - 0.0025 18.2 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad2 Baculo_PEP_C PF04513.12 EFI27943.1 - 1.9 8.5 12.6 0.71 9.9 0.1 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 EFI27943.1 - 9.6 6.0 14.6 0.79 9.5 4.2 3.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Alpha-amylase PF00128.24 EFI27944.1 - 1.6e-21 77.2 0.0 7.4e-21 75.1 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EFI27944.1 - 3.5e-06 25.5 0.2 0.15 10.3 0.0 3.2 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EFI27944.1 - 0.005 17.0 0.3 0.02 15.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Foamy_virus_ENV PF03408.14 EFI27945.1 - 0.22 9.3 0.1 0.24 9.2 0.1 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Fra10Ac1 PF09725.9 EFI27946.1 - 8.2e-14 51.8 2.3 4e-09 36.6 0.0 2.4 1 1 1 2 2 2 2 Folate-sensitive fragile site protein Fra10Ac1 Aa_trans PF01490.18 EFI27948.1 - 5.2e-83 279.0 26.6 6.1e-83 278.8 26.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cellulase PF00150.18 EFI27950.1 - 2.3e-10 40.4 0.0 3.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4449 PF14613.6 EFI27952.1 - 0.11 12.6 2.6 0.24 11.5 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) Golgin_A5 PF09787.9 EFI27952.1 - 0.11 11.9 1.6 0.18 11.2 1.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF883 PF05957.13 EFI27952.1 - 0.22 12.1 6.3 0.81 10.3 1.9 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Cullin PF00888.22 EFI27953.1 - 1.1e-177 592.4 0.0 4.2e-98 329.6 0.0 2.1 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 EFI27953.1 - 4.1e-28 97.2 1.4 1.3e-27 95.6 0.8 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EFI27953.1 - 0.039 14.3 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Penicillinase repressor DnaJ PF00226.31 EFI27955.1 - 1.6e-14 53.8 0.1 2.8e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain CARMIL_C PF16000.5 EFI27955.1 - 0.76 9.3 10.2 0.98 9.0 9.9 1.4 1 1 0 1 1 1 0 CARMIL C-terminus DnaJ_C PF01556.18 EFI27956.1 - 6.6e-08 32.8 0.0 8.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain Pheromone PF08015.11 EFI27958.1 - 0.0002 22.4 0.8 0.28 12.3 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone MINDY_DUB PF04424.13 EFI27969.1 - 2.3e-13 50.2 0.0 4.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase Pheromone PF08015.11 EFI27970.1 - 0.00038 21.4 3.8 0.018 16.1 0.3 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI27971.1 - 0.049 14.7 3.8 0.64 11.1 3.8 2.3 1 1 0 1 1 1 0 Fungal mating-type pheromone HOIP-UBA PF16678.5 EFI27975.1 - 0.08 12.9 0.3 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 HOIP UBA domain pair F-box-like PF12937.7 EFI27977.1 - 4.3e-05 23.3 0.2 9.6e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like UCH PF00443.29 EFI27979.1 - 2e-44 152.0 0.0 3.9e-44 151.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EFI27979.1 - 1.4e-18 67.6 5.7 8.6e-17 61.7 5.7 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HalOD2 PF18547.1 EFI27979.1 - 1.5 8.8 5.8 20 5.2 0.1 3.3 3 0 0 3 3 3 0 Halobacterial output domain 2 RF-1 PF00472.20 EFI27981.1 - 4.4e-21 75.0 0.6 6e-21 74.5 0.6 1.1 1 0 0 1 1 1 1 RF-1 domain Lipase_3 PF01764.25 EFI27982.1 - 2.4e-12 46.9 0.0 5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EFI27982.1 - 0.0059 16.3 0.0 0.0088 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EFI27982.1 - 0.035 14.7 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EFI27982.1 - 0.058 13.2 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EFI27982.1 - 0.13 11.5 0.0 0.4 9.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 EFI27982.1 - 0.15 11.8 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 EFI27982.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase LRR_4 PF12799.7 EFI27983.1 - 0.017 15.6 0.0 1.7 9.2 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Phage_lysozyme PF00959.19 EFI27985.1 - 9.9e-15 54.9 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme DEC-1_N PF04625.13 EFI27985.1 - 1 8.3 22.1 1.9 7.4 22.1 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PIG-X PF08320.12 EFI27986.1 - 1.6e-19 70.7 0.0 1.9e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Pheromone PF08015.11 EFI27987.1 - 4.3e-05 24.5 1.4 0.0015 19.5 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI27988.1 - 0.00013 23.0 2.0 0.0015 19.6 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI27989.1 - 1.3e-05 26.1 1.5 0.0013 19.8 0.2 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI27991.1 - 2e-05 25.6 1.6 0.0017 19.3 0.2 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI27992.1 - 3.8e-05 24.6 1.2 0.0024 18.9 1.2 2.0 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.11 EFI27993.1 - 1.7e-05 25.7 1.7 0.0024 18.9 0.2 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone WaaY PF06176.11 EFI27995.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_S49_N PF08496.10 EFI27995.1 - 1.3 9.1 6.2 1.8 8.6 6.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3886 PF13025.6 EFI27995.1 - 5.3 7.3 15.6 10 6.4 15.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) RCDG1 PF15725.5 EFI27996.1 - 3.3 8.2 7.0 0.44 11.0 2.9 1.6 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Pkinase_fungal PF17667.1 EFI27999.1 - 2e-10 40.0 0.0 5.9e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EFI27999.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain KDZ PF18758.1 EFI28001.1 - 4.5e-42 144.2 0.1 9.8e-42 143.1 0.1 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI28001.1 - 1.6e-22 79.7 0.2 3.6e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EFI28001.1 - 0.011 15.5 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases CENP-B_dimeris PF09026.10 EFI28001.1 - 0.029 14.7 11.2 0.12 12.7 1.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ceramidase_alk PF04734.13 EFI28004.1 - 0.16 10.5 0.4 0.19 10.3 0.4 1.0 1 0 0 1 1 1 0 Neutral/alkaline non-lysosomal ceramidase, N-terminal Plavaka PF18759.1 EFI28006.1 - 5.9e-126 420.1 0.0 8e-126 419.6 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase KDZ PF18758.1 EFI28012.1 - 6.6e-51 173.1 0.0 1.1e-50 172.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 EFI28012.1 - 3.6e-05 23.7 0.1 6.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ABC_tran_CTD PF16326.5 EFI28012.1 - 0.01 16.1 0.1 0.031 14.5 0.1 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain AT_hook PF02178.19 EFI28012.1 - 0.11 12.4 20.3 0.15 12.0 5.9 3.0 2 0 0 2 2 2 0 AT hook motif DLEU7 PF15760.5 EFI28012.1 - 2.3 7.7 7.7 4.7 6.7 7.7 1.4 1 0 0 1 1 1 0 Leukemia-associated protein 7 CxC1 PF18802.1 EFI28013.1 - 9.6e-09 35.3 0.6 3.5e-08 33.5 0.2 2.0 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 EFI28013.1 - 6.2e-05 23.1 0.3 0.00015 21.8 0.3 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC3 PF18804.1 EFI28013.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Pheromone PF08015.11 EFI28015.1 - 0.004 18.2 0.9 0.063 14.3 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI28016.1 - 1.1e-05 26.4 1.4 6.8e-05 23.8 0.2 1.9 1 1 1 2 2 2 1 Fungal mating-type pheromone Pheromone PF08015.11 EFI28017.1 - 0.00085 20.3 3.7 0.022 15.8 0.2 2.3 1 1 1 2 2 2 2 Fungal mating-type pheromone PT PF04886.12 EFI28017.1 - 0.035 13.6 10.0 0.074 12.6 10.0 1.4 1 0 0 1 1 1 0 PT repeat Pheromone PF08015.11 EFI28018.1 - 0.0068 17.4 4.8 0.061 14.4 4.8 2.4 1 1 0 1 1 1 1 Fungal mating-type pheromone AT_hook PF02178.19 EFI28022.1 - 3.3 7.9 6.2 1.8 8.7 0.2 3.0 3 0 0 3 3 3 0 AT hook motif Tet_JBP PF12851.7 EFI28023.1 - 1e-07 31.7 0.0 3e-07 30.1 0.0 1.6 1 1 1 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily DUF4164 PF13747.6 EFI28024.1 - 0.0076 16.5 3.0 0.09 13.1 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4164) FlgN PF05130.12 EFI28024.1 - 0.018 15.5 0.1 0.029 14.9 0.1 1.4 1 0 0 1 1 1 0 FlgN protein DUF3670 PF12419.8 EFI28024.1 - 0.048 13.5 2.5 0.53 10.1 0.4 2.3 1 1 1 2 2 2 0 SNF2 Helicase protein SNARE PF05739.19 EFI28024.1 - 0.062 13.3 0.4 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 SNARE domain Cep57_CLD_2 PF14197.6 EFI28024.1 - 0.064 13.3 0.2 0.95 9.6 0.1 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Cauli_VI PF01693.16 EFI28025.1 - 7.3e-09 35.8 0.0 1.1e-07 32.0 0.0 2.3 2 0 0 2 2 2 1 Caulimovirus viroplasmin F-box-like PF12937.7 EFI28027.1 - 0.0021 17.9 0.1 0.0037 17.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like G-alpha PF00503.20 EFI28030.1 - 6.2e-111 371.0 0.0 4.9e-106 354.9 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 EFI28030.1 - 1.6e-10 40.7 0.3 9.8e-09 34.9 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family DAHP_synth_2 PF01474.16 EFI28031.1 - 6.4e-99 331.4 0.0 7.3e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DAHP_synth_2 PF01474.16 EFI28032.1 - 6.8e-23 80.9 0.0 3.3e-20 72.0 0.0 2.8 1 1 2 3 3 3 2 Class-II DAHP synthetase family SelP_N PF04592.14 EFI28033.1 - 0.95 8.8 4.5 2.2 7.6 4.5 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region IBR PF01485.21 EFI28034.1 - 2.8e-09 37.1 18.3 4.5e-06 26.8 7.1 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 EFI28034.1 - 4 7.8 13.3 3.5 7.9 0.0 4.5 2 1 2 4 4 4 0 zinc-ribbon Zn_Tnp_IS91 PF14319.6 EFI28034.1 - 8.8 6.4 19.2 7.6 6.6 4.7 2.8 1 1 1 2 2 2 0 Transposase zinc-binding domain Pkinase_fungal PF17667.1 EFI28035.1 - 1.5e-05 24.0 0.0 0.05 12.4 0.0 2.0 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EFI28035.1 - 0.029 14.3 0.1 0.046 13.6 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1996 PF09362.10 EFI28038.1 - 7.5e-80 268.3 0.1 9.3e-80 268.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.18 EFI28038.1 - 2.3e-11 43.5 15.1 2.3e-11 43.5 15.1 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain Caudo_bapla16 PF16792.5 EFI28040.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 Helicase_C PF00271.31 EFI28041.1 - 7e-15 55.3 0.0 2.2e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EFI28041.1 - 1.2e-09 38.2 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EFI28041.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 EFI28041.1 - 0.0042 17.8 0.4 0.011 16.5 0.4 1.7 1 0 0 1 1 1 1 RecQ zinc-binding Opi1 PF08618.10 EFI28041.1 - 0.05 12.8 4.6 0.035 13.4 2.6 1.6 2 0 0 2 2 2 0 Transcription factor Opi1 Bestrophin PF01062.21 EFI28042.1 - 0.019 14.4 0.4 0.021 14.2 0.4 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.21 EFI28043.1 - 3.1e-09 36.6 2.5 4e-08 33.0 0.7 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DHC_N1 PF08385.12 EFI28043.1 - 0.0094 14.6 0.1 0.014 14.1 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 CBM_19 PF03427.13 EFI28044.1 - 0.0089 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) Leu_zip PF15294.6 EFI28046.1 - 0.00012 21.7 5.7 0.00018 21.1 5.7 1.2 1 0 0 1 1 1 1 Leucine zipper HOOK PF05622.12 EFI28046.1 - 0.0021 16.3 3.8 0.0031 15.7 3.8 1.2 1 0 0 1 1 1 1 HOOK protein Fez1 PF06818.15 EFI28046.1 - 0.0035 17.8 2.6 0.0078 16.7 2.6 1.6 1 0 0 1 1 1 1 Fez1 MAGI_u1 PF16663.5 EFI28046.1 - 0.013 15.6 2.7 0.4 10.8 3.3 2.8 2 0 0 2 2 2 0 Unstructured region on MAGI DUF2203 PF09969.9 EFI28046.1 - 0.031 15.0 2.1 0.073 13.8 2.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HMMR_N PF15905.5 EFI28046.1 - 0.38 10.2 7.3 0.68 9.4 7.3 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ERM PF00769.19 EFI28046.1 - 0.44 10.3 13.9 0.93 9.3 13.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family EzrA PF06160.12 EFI28046.1 - 0.5 8.5 8.5 0.75 7.9 8.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4200 PF13863.6 EFI28046.1 - 0.63 10.4 11.2 1.3 9.4 11.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Phage_GP20 PF06810.11 EFI28046.1 - 0.69 9.7 6.6 1.1 9.0 6.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.6 EFI28046.1 - 1.4 8.2 11.9 0.67 9.3 7.9 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EFI28046.1 - 2.2 7.3 7.2 4.1 6.4 7.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EFI28046.1 - 3.3 7.0 5.1 6 6.1 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EFI28046.1 - 8.2 6.5 8.2 15 5.6 8.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 EFI28046.1 - 9.9 6.4 14.2 20 5.4 14.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding F-box PF00646.33 EFI28049.1 - 7e-07 29.0 0.1 1.8e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EFI28049.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like Methyltransf_29 PF03141.16 EFI28049.1 - 0.097 11.2 0.0 4.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CBM_1 PF00734.18 EFI28051.1 - 1.8e-06 27.8 3.2 3e-06 27.1 3.2 1.4 1 0 0 1 1 1 1 Fungal cellulose binding domain PIF1 PF05970.14 EFI28054.1 - 2.6e-24 86.1 0.0 6.3e-24 84.8 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 EFI28054.1 - 2.4e-11 43.7 0.0 4.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EFI28054.1 - 5.2e-09 36.6 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain YycH PF07435.11 EFI28054.1 - 0.017 14.1 2.2 1.2 8.0 0.2 2.2 2 0 0 2 2 2 0 YycH protein TrwB_AAD_bind PF10412.9 EFI28054.1 - 0.044 12.7 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 EFI28054.1 - 0.056 13.2 0.0 3.7 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EFI28054.1 - 0.098 12.6 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HMW1C_N PF18071.1 EFI28055.1 - 0.05 13.4 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 HMW1C N-terminal Peptidase_M22 PF00814.25 EFI28055.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family AAA_22 PF13401.6 EFI28061.1 - 0.008 16.4 0.0 0.013 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EFI28061.1 - 0.018 14.9 0.1 0.032 14.1 0.1 1.4 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 EFI28061.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.7 EFI28062.1 - 2.4e-28 98.5 0.0 1.9e-12 47.6 0.0 3.9 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EFI28062.1 - 2.9e-21 73.3 0.1 0.00057 20.1 0.0 6.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EFI28062.1 - 1.2e-20 73.3 0.8 9.1e-10 38.6 0.1 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 EFI28062.1 - 1.1e-17 64.2 0.2 0.0005 20.6 0.0 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EFI28062.1 - 7.8e-15 54.6 0.0 0.47 11.0 0.0 6.3 6 1 0 6 6 6 5 Ankyrin repeat Tropomyosin_1 PF12718.7 EFI28064.1 - 4.1e-06 27.0 34.5 0.0007 19.8 13.1 2.7 1 1 1 2 2 2 2 Tropomyosin like Macoilin PF09726.9 EFI28064.1 - 0.0036 15.9 25.5 0.0053 15.4 25.5 1.1 1 0 0 1 1 1 1 Macoilin family Cep57_CLD_2 PF14197.6 EFI28064.1 - 0.0039 17.2 5.5 0.0039 17.2 5.5 4.5 3 1 1 4 4 4 1 Centrosome localisation domain of PPC89 Spc7 PF08317.11 EFI28064.1 - 0.0074 15.2 35.1 0.16 10.9 14.4 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein HALZ PF02183.18 EFI28064.1 - 0.013 15.7 4.9 0.013 15.7 4.9 4.6 5 0 0 5 5 5 0 Homeobox associated leucine zipper SHE3 PF17078.5 EFI28064.1 - 0.038 13.7 21.1 0.6 9.8 5.5 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 GAS PF13851.6 EFI28064.1 - 0.039 13.3 35.9 0.15 11.4 27.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EFI28064.1 - 0.045 13.6 33.8 0.12 12.2 24.6 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EFI28064.1 - 0.059 13.5 18.2 0.096 12.8 0.9 4.1 4 0 0 4 4 3 0 bZIP transcription factor CENP-F_leu_zip PF10473.9 EFI28064.1 - 0.09 12.8 30.2 0.48 10.5 11.2 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EFI28064.1 - 0.098 12.7 48.4 1.9 8.6 22.7 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 EFI28064.1 - 0.11 12.4 34.9 0.69 9.9 1.6 4.4 2 1 1 4 4 4 0 Prefoldin subunit bZIP_2 PF07716.15 EFI28064.1 - 0.12 12.5 33.0 0.093 12.8 4.8 4.7 4 0 0 4 4 4 0 Basic region leucine zipper HAUS-augmin3 PF14932.6 EFI28064.1 - 0.22 11.1 41.6 0.061 12.9 8.7 3.7 2 1 2 4 4 4 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 EFI28064.1 - 0.24 11.6 40.1 1.8 8.8 7.0 3.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 EFI28064.1 - 0.25 11.7 39.8 0.42 11.0 16.5 3.4 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Herpes_UL6 PF01763.16 EFI28064.1 - 0.3 9.5 21.8 0.31 9.5 5.3 2.4 1 1 1 2 2 2 0 Herpesvirus UL6 like Taxilin PF09728.9 EFI28064.1 - 0.65 9.1 36.3 5.4 6.1 36.2 2.2 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Filament PF00038.21 EFI28064.1 - 0.66 9.5 35.5 1.3 8.6 20.1 2.6 2 1 1 3 3 3 0 Intermediate filament protein CEP63 PF17045.5 EFI28064.1 - 1.1 9.1 35.2 3.1e+02 1.1 34.7 2.4 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa IFT57 PF10498.9 EFI28064.1 - 1.1 8.1 28.7 2.9 6.7 19.9 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CALCOCO1 PF07888.11 EFI28064.1 - 1.2 7.9 35.6 2.1 7.1 35.6 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.8 EFI28064.1 - 1.5 8.9 44.5 0.086 12.9 5.3 3.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.9 EFI28064.1 - 1.5 8.7 30.6 0.09 12.7 9.2 3.4 1 1 3 4 4 4 0 Axonemal dynein light chain DUF1664 PF07889.12 EFI28064.1 - 1.7 8.7 19.3 1.9 8.5 0.5 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 EFI28064.1 - 2 8.0 40.8 1.3 8.7 5.4 3.5 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Phlebovirus_NSM PF07246.11 EFI28064.1 - 2.3 7.5 15.7 0.51 9.7 11.1 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M BBS2_C PF14782.6 EFI28064.1 - 2.8 6.6 24.4 0.11 11.3 2.5 3.1 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal DUF641 PF04859.12 EFI28064.1 - 4.2 7.7 29.3 7.3 6.9 2.6 3.5 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF1993 PF09351.10 EFI28064.1 - 4.6 7.4 17.8 1.6 8.8 7.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) ZapB PF06005.12 EFI28064.1 - 5.2 7.6 40.2 0.1 13.1 7.0 4.4 2 1 1 3 3 2 0 Cell division protein ZapB NuA4 PF09340.10 EFI28064.1 - 5.2 7.0 8.5 27 4.7 0.2 3.8 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Atg14 PF10186.9 EFI28064.1 - 5.7 5.9 33.6 0.24 10.4 15.1 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 EFI28064.1 - 6.3 6.2 35.3 0.22 11.0 29.1 1.7 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 EFI28064.1 - 6.7 6.9 24.7 15 5.8 8.8 3.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 EFI28064.1 - 8 5.6 24.4 1.3 8.2 7.1 2.4 1 1 2 3 3 3 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 EFI28064.1 - 8.4 6.7 23.7 27 5.1 8.8 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Golgin_A5 PF09787.9 EFI28064.1 - 8.6 5.7 37.1 2.3 7.6 23.3 2.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 YabA PF06156.13 EFI28064.1 - 9.2 7.0 23.4 11 6.7 7.5 4.0 1 1 2 3 3 3 0 Initiation control protein YabA DivIVA PF05103.13 EFI28064.1 - 9.3 6.3 35.8 2.5 8.2 17.3 3.7 1 1 1 2 2 2 0 DivIVA protein MbeB_N PF04837.12 EFI28071.1 - 0.16 12.3 0.2 0.39 11.1 0.2 1.6 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Kdo PF06293.14 EFI28072.1 - 2.4e-06 27.1 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EFI28072.1 - 0.0023 17.5 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH_6_hur PF04655.14 EFI28072.1 - 0.0026 17.2 0.0 0.018 14.4 0.0 2.3 3 0 0 3 3 3 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Choline_kinase PF01633.20 EFI28072.1 - 0.025 14.2 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 EFI28072.1 - 0.035 14.0 0.3 0.42 10.5 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 EFI28072.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF2828 PF11443.8 EFI28073.1 - 5.3e-229 761.5 0.0 6.1e-229 761.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Ribonucleas_3_2 PF11469.8 EFI28073.1 - 0.14 12.6 0.3 1.5 9.3 0.1 2.5 3 0 0 3 3 3 0 Ribonuclease III SRP_TPR_like PF17004.5 EFI28075.1 - 1.9e-16 60.1 1.3 2.5e-16 59.7 1.3 1.1 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_19 PF14559.6 EFI28075.1 - 1.1e-08 35.5 7.0 7e-06 26.5 0.2 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat SRP72 PF08492.12 EFI28075.1 - 1.4e-07 31.8 0.1 1.4e-07 31.8 0.1 2.5 3 0 0 3 3 3 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 EFI28075.1 - 1.9e-05 24.8 6.0 0.01 16.0 0.9 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EFI28075.1 - 0.00013 22.0 4.2 0.0011 19.1 0.1 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EFI28075.1 - 0.0002 21.2 7.2 0.96 9.7 0.3 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EFI28075.1 - 0.00035 21.2 6.7 5 8.2 0.0 4.2 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EFI28075.1 - 0.001 19.7 5.5 0.14 12.8 4.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EFI28075.1 - 0.0011 19.0 1.2 2.3 8.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EFI28075.1 - 0.0068 17.0 4.9 0.61 10.9 0.2 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EFI28075.1 - 0.025 14.3 3.4 7.1 6.4 0.2 3.3 3 0 0 3 3 3 0 TPR repeat EzrA PF06160.12 EFI28075.1 - 0.029 12.6 0.2 0.043 12.0 0.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_1 PF00515.28 EFI28075.1 - 0.03 14.2 3.0 1.3 8.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EFI28075.1 - 0.037 14.1 0.2 6 7.0 0.0 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF2989 PF11207.8 EFI28075.1 - 0.18 11.5 1.7 0.3 10.8 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2989) ASCH PF04266.14 EFI28076.1 - 0.19 12.3 0.0 0.57 10.8 0.0 1.8 2 0 0 2 2 2 0 ASCH domain Ceramidase_alk PF04734.13 EFI28077.1 - 1.7e-214 713.2 0.0 2e-214 713.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EFI28077.1 - 6.1e-58 195.4 0.0 1.1e-57 194.5 0.0 1.5 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Fumarate_red_C PF02300.17 EFI28083.1 - 1.4 9.0 2.9 2.1 8.5 2.1 1.7 2 0 0 2 2 2 0 Fumarate reductase subunit C KI67R PF08065.12 EFI28083.1 - 3.5 8.2 18.3 6.8 7.3 0.0 2.8 2 0 0 2 2 2 0 KI67R (NUC007) repeat DUF5384 PF17358.2 EFI28085.1 - 0.15 12.1 8.6 0.24 11.5 8.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5384) Git3 PF11710.8 EFI28086.1 - 4.1e-09 36.5 6.7 1.1e-08 35.1 6.7 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 EFI28086.1 - 0.00045 19.4 3.0 0.00045 19.4 3.0 1.5 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor BatD PF13584.6 EFI28086.1 - 0.022 13.6 0.3 0.95 8.2 0.2 2.1 2 0 0 2 2 2 0 Oxygen tolerance Orf78 PF06024.12 EFI28086.1 - 0.036 14.4 0.4 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 Orf78 (ac78) F-box-like_2 PF13013.6 EFI28088.1 - 9.8e-12 44.8 0.1 1.8e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 F-box-like domain LRR_4 PF12799.7 EFI28088.1 - 0.0016 18.8 6.4 2.2 8.8 0.0 5.1 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EFI28088.1 - 0.0061 16.4 1.9 0.007 16.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain Cmc1 PF08583.10 EFI28088.1 - 0.17 11.9 0.4 0.41 10.7 0.4 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like F-box-like_2 PF13013.6 EFI28089.1 - 3.7e-11 42.9 0.5 1.2e-10 41.3 0.2 1.9 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.33 EFI28089.1 - 9.4e-05 22.2 0.5 0.00032 20.5 0.5 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EFI28089.1 - 0.00015 21.6 0.3 0.00041 20.2 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 EFI28090.1 - 0.029 14.3 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.6 EFI28091.1 - 1.3e-07 31.6 0.2 3.1e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.33 EFI28091.1 - 0.0014 18.5 0.2 0.0046 16.8 0.2 2.0 1 0 0 1 1 1 1 F-box domain Glyco_transf_8 PF01501.20 EFI28092.1 - 0.0085 15.7 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 OPT PF03169.15 EFI28093.1 - 3.5e-186 620.5 39.2 4.1e-186 620.3 39.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Rrn6 PF10214.9 EFI28093.1 - 0.33 9.4 7.2 0.89 8.0 7.2 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Bud13 PF09736.9 EFI28093.1 - 6 7.3 21.8 0.18 12.2 11.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex HUN PF08729.10 EFI28095.1 - 2.3e-06 27.5 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Mito_carr PF00153.27 EFI28098.1 - 3.2e-38 129.6 0.2 1e-11 44.6 0.2 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein F-box-like PF12937.7 EFI28099.1 - 3.4e-07 30.0 0.3 9e-07 28.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like Smr PF01713.21 EFI28101.1 - 5.7e-12 45.8 0.1 8.1e-12 45.3 0.1 1.2 1 0 0 1 1 1 1 Smr domain DUF4265 PF14085.6 EFI28101.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) UvdE PF03851.14 EFI28105.1 - 2e-77 260.2 0.0 2.5e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 EFI28105.1 - 0.0022 17.5 0.0 0.0062 16.0 0.0 1.7 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel DUF4037 PF13228.6 EFI28105.1 - 0.15 12.9 0.0 0.51 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4037) COG7 PF10191.9 EFI28106.1 - 2.8e-82 277.2 10.5 2.2e-53 181.7 2.3 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) RasGEF PF00617.19 EFI28106.1 - 0.18 12.0 1.6 2.5 8.3 0.2 2.7 2 1 0 2 2 2 0 RasGEF domain Prp19 PF08606.11 EFI28107.1 - 0.054 13.5 0.2 15 5.6 0.1 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like DctP PF03480.13 EFI28107.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Hist_deacetyl PF00850.19 EFI28108.1 - 1.6e-89 300.4 0.1 3.8e-89 299.2 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.9 EFI28108.1 - 2.4e-41 141.6 0.0 3.3e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Voltage_CLC PF00654.20 EFI28110.1 - 2.6e-91 306.5 20.6 2.6e-91 306.5 20.6 2.1 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EFI28110.1 - 0.022 15.2 0.0 0.84 10.1 0.0 2.5 2 0 0 2 2 2 0 CBS domain GLTSCR1 PF15249.6 EFI28111.1 - 5.5e-30 103.8 0.1 9.3e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein CCDC-167 PF15188.6 EFI28111.1 - 0.088 13.2 2.4 0.18 12.2 2.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ank_4 PF13637.6 EFI28112.1 - 9.9e-07 29.2 0.0 6.9e-05 23.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EFI28112.1 - 0.0006 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EFI28112.1 - 0.0012 19.1 0.0 0.0031 17.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EFI28112.1 - 0.078 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ribosomal_S8e PF01201.22 EFI28113.1 - 1.6e-49 167.6 0.8 2.7e-49 166.9 0.1 1.6 1 1 1 2 2 2 1 Ribosomal protein S8e Cdc13_OB4_dimer PF18233.1 EFI28113.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Cdc13 OB4 dimerization domain CYYR1 PF10873.8 EFI28115.1 - 0.1 13.1 0.1 0.69 10.4 0.1 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 EB PF01683.18 EFI28116.1 - 2.6e-05 24.4 17.8 0.0079 16.5 0.0 4.2 2 1 1 3 3 3 2 EB module Dickkopf_N PF04706.12 EFI28116.1 - 0.12 12.9 33.8 0.048 14.1 9.0 4.4 4 0 0 4 4 4 0 Dickkopf N-terminal cysteine-rich region GATA PF00320.27 EFI28118.1 - 3e-18 65.1 2.0 5.8e-18 64.2 2.0 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EFI28118.1 - 1.2e-11 44.2 1.6 3.3e-11 42.8 1.6 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SNURF PF07192.11 EFI28118.1 - 0.46 10.3 2.3 3.4 7.6 0.7 2.8 3 0 0 3 3 3 0 SNURF/RPN4 protein Sec7 PF01369.20 EFI28119.1 - 1.7e-30 106.1 0.1 7.1e-30 104.0 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 EFI28119.1 - 1.9e-29 102.5 0.0 3.9e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EFI28119.1 - 0.0001 22.8 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 PH domain SLAC1 PF03595.17 EFI28120.1 - 1e-67 228.7 54.3 1.2e-67 228.5 54.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.17 EFI28121.1 - 3.1e-38 131.9 25.8 3.5e-38 131.7 25.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel UDPGP PF01704.18 EFI28122.1 - 8.6e-138 459.4 0.0 3.1e-114 381.9 0.0 2.0 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase HhH-GPD PF00730.25 EFI28123.1 - 2e-16 60.4 0.0 3.5e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Oxidored_q6 PF01058.22 EFI28124.1 - 2e-22 79.4 0.1 3.1e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Amidohydro_1 PF01979.20 EFI28127.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family MRP-S33 PF08293.11 EFI28128.1 - 2.6e-32 110.9 0.2 3.7e-32 110.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Astro_capsid_p2 PF16580.5 EFI28128.1 - 0.042 13.3 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 C-terminal tail of astrovirus capsid projection or spike F-box-like PF12937.7 EFI28129.1 - 4.5e-07 29.6 0.5 2.2e-06 27.4 0.5 2.3 1 0 0 1 1 1 1 F-box-like Acetyltransf_1 PF00583.25 EFI28130.1 - 6.6e-07 29.6 0.0 9.3e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EFI28130.1 - 0.0022 18.4 0.0 0.0055 17.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EFI28130.1 - 0.0032 18.1 0.0 0.0039 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EFI28130.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fcf1 PF04900.12 EFI28132.1 - 1.8e-39 134.1 2.2 3.1e-39 133.4 2.2 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EFI28132.1 - 2.1e-11 44.2 0.1 8e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 PIN like domain Lyase_aromatic PF00221.19 EFI28134.1 - 7.1e-148 493.1 0.9 9.3e-148 492.7 0.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Ocnus PF05005.15 EFI28134.1 - 0.053 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) NADH-UOR_E PF16514.5 EFI28134.1 - 0.27 11.6 0.7 45 4.5 0.0 3.8 4 0 0 4 4 4 0 putative NADH-ubiquinone oxidoreductase chain E DAO PF01266.24 EFI28135.1 - 2.9e-27 96.2 0.0 3.2e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EFI28135.1 - 2.8e-06 26.8 0.0 0.0042 16.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EFI28135.1 - 2e-05 23.9 0.1 0.002 17.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EFI28135.1 - 4.7e-05 22.7 0.0 0.0062 15.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 EFI28135.1 - 0.00073 19.6 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EFI28135.1 - 0.0024 18.0 0.0 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EFI28135.1 - 0.0028 17.0 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EFI28135.1 - 0.0058 15.9 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EFI28135.1 - 0.006 16.6 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EFI28135.1 - 0.0069 15.1 0.0 0.85 8.2 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.18 EFI28135.1 - 0.045 14.0 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain DNA_RNApol_7kD PF03604.13 EFI28135.1 - 0.046 13.4 1.3 0.11 12.2 1.3 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit ThiF PF00899.21 EFI28135.1 - 0.069 12.5 0.2 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 ThiF family K_oxygenase PF13434.6 EFI28135.1 - 0.078 12.1 0.0 0.46 9.6 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Tyrosinase PF00264.20 EFI28136.1 - 5.6e-53 180.5 0.7 5.6e-53 180.5 0.7 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EFI28136.1 - 3.8e-32 111.5 0.0 6.2e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Tyosinase C-terminal domain Glyco_transf_8 PF01501.20 EFI28137.1 - 8.3e-07 28.8 0.7 0.00025 20.7 0.7 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Tox-GHH PF15636.6 EFI28137.1 - 0.057 13.4 0.6 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Glyco_transf_24 PF18404.1 EFI28137.1 - 0.08 12.3 0.1 0.72 9.2 0.1 2.1 1 1 1 2 2 2 0 Glucosyltransferase 24 DUF1917 PF08939.10 EFI28138.1 - 7.3e-27 94.9 0.0 7.3e-27 94.9 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) SAP PF02037.27 EFI28138.1 - 0.11 12.3 0.7 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 SAP domain CDC45 PF02724.14 EFI28138.1 - 6 5.0 17.7 0.33 9.2 12.1 1.6 2 0 0 2 2 2 0 CDC45-like protein F-box-like PF12937.7 EFI28139.1 - 0.0023 17.8 1.4 0.018 14.9 1.4 2.3 1 1 0 1 1 1 1 F-box-like Nop14 PF04147.12 EFI28139.1 - 0.02 13.2 13.6 0.031 12.5 13.6 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EFI28139.1 - 0.052 11.6 23.9 0.095 10.8 23.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EFI28139.1 - 0.1 12.0 16.0 0.18 11.2 16.0 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EFI28139.1 - 0.13 10.5 9.7 0.2 9.9 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Pilosulin PF17499.2 EFI28139.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Ant venom peptides Sigma70_ner PF04546.13 EFI28139.1 - 1.1 9.1 16.0 0.072 13.0 10.9 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Mpp10 PF04006.12 EFI28139.1 - 1.7 7.0 14.0 2.6 6.4 14.0 1.2 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 EFI28139.1 - 2.3 7.5 13.0 3.6 6.8 13.0 1.2 1 0 0 1 1 1 0 BUD22 Pes-10 PF07149.11 EFI28139.1 - 7.9 5.4 14.0 14 4.6 14.0 1.3 1 0 0 1 1 1 0 Pes-10 DUF4637 PF15470.6 EFI28139.1 - 9.1 6.0 12.3 21 4.8 12.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ifi-6-16 PF06140.13 EFI28140.1 - 2.4e-08 33.8 3.8 5.4e-08 32.6 3.9 1.5 2 0 0 2 2 2 1 Interferon-induced 6-16 family Rrn6 PF10214.9 EFI28140.1 - 0.02 13.4 0.2 0.023 13.2 0.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Competence PF03772.16 EFI28140.1 - 0.11 11.7 3.9 0.033 13.5 0.8 1.8 2 0 0 2 2 2 0 Competence protein zf-ZPR1 PF03367.13 EFI28140.1 - 0.19 11.6 0.5 0.94 9.3 0.1 1.9 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Ifi-6-16 PF06140.13 EFI28141.1 - 5.4e-08 32.6 1.9 1.1e-07 31.7 1.9 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family Cytochrom_B562 PF07361.11 EFI28141.1 - 0.11 13.1 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b562 Exc PF07825.11 EFI28142.1 - 0.099 12.6 0.7 0.32 11.0 0.3 2.1 1 1 0 1 1 1 0 Excisionase-like protein MIF4G PF02854.19 EFI28143.1 - 2.8e-44 151.3 9.3 5.9e-29 101.2 0.0 3.9 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 EFI28143.1 - 2.5e-27 96.3 5.5 2.5e-27 96.3 5.5 3.6 3 1 1 4 4 4 1 Up-frameshift suppressor 2 Pkinase PF00069.25 EFI28144.1 - 1.7e-49 168.6 0.0 2.4e-35 122.2 0.2 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28144.1 - 3e-23 82.4 0.0 7.8e-19 68.0 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI28144.1 - 3.8e-07 29.2 0.1 6.1e-07 28.6 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EFI28144.1 - 6e-07 29.6 0.0 0.0021 18.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EFI28144.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EFI28144.1 - 0.0018 17.9 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EFI28144.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EFI28144.1 - 0.034 13.0 0.0 0.13 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) RabGAP-TBC PF00566.18 EFI28145.1 - 6.7e-54 182.8 0.1 6.7e-54 182.8 0.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain APG6_N PF17675.1 EFI28145.1 - 0.0056 17.2 6.9 0.0056 17.2 6.9 2.7 3 0 0 3 3 3 1 Apg6 coiled-coil region DUF5600 PF18150.1 EFI28145.1 - 0.0067 17.0 0.3 0.017 15.7 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Prp19 PF08606.11 EFI28145.1 - 0.02 14.8 2.0 0.02 14.8 2.0 2.3 2 1 0 2 2 2 0 Prp19/Pso4-like DUF2935 PF11155.8 EFI28145.1 - 0.049 14.0 0.7 0.13 12.6 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) LURAP PF14854.6 EFI28145.1 - 0.17 11.8 2.1 0.54 10.2 2.1 1.9 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF3492 PF11997.8 EFI28145.1 - 0.48 10.1 2.1 0.4 10.4 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) DivIVA PF05103.13 EFI28145.1 - 0.85 9.7 7.1 6.4 6.9 7.1 2.4 1 1 0 1 1 1 0 DivIVA protein DivIC PF04977.15 EFI28145.1 - 2.1 8.2 10.9 0.93 9.3 0.9 3.0 2 1 1 3 3 3 0 Septum formation initiator ABC1 PF03109.16 EFI28146.1 - 2.4e-34 118.1 0.0 6.7e-34 116.6 0.0 1.8 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.22 EFI28146.1 - 0.00015 21.5 0.4 0.00074 19.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family GHMP_kinases_N PF00288.26 EFI28147.1 - 3.4e-15 56.0 0.9 7.3e-15 55.0 0.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EFI28147.1 - 2e-07 31.3 0.0 4.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal LSM PF01423.22 EFI28148.1 - 1.6e-08 34.1 0.1 2.3e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain RabGAP-TBC PF00566.18 EFI28151.1 - 1.1e-47 162.4 0.1 1.8e-47 161.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3731 PF12531.8 EFI28152.1 - 0.00044 20.1 1.8 0.0005 20.0 1.8 1.1 1 0 0 1 1 1 1 DNA-K related protein Lzipper-MIP1 PF14389.6 EFI28152.1 - 0.014 15.7 0.1 0.018 15.3 0.1 1.1 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Metal_resist PF13801.6 EFI28152.1 - 8.7 6.6 9.3 0.83 9.9 2.1 2.4 2 1 0 2 2 2 0 Heavy-metal resistance DUF2009 PF09418.10 EFI28153.1 - 0.15 11.1 0.2 0.21 10.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) DUF2959 PF11172.8 EFI28153.1 - 0.29 11.3 1.8 3.3 7.8 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) IMS PF00817.20 EFI28154.1 - 1.6e-47 161.3 0.0 3.5e-47 160.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EFI28154.1 - 1.3e-16 61.4 0.3 3.8e-16 59.8 0.3 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EFI28154.1 - 1.1e-06 28.6 0.0 2.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif RNF220 PF15926.5 EFI28154.1 - 0.032 13.9 0.1 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 ATP_transf PF09830.9 EFI28156.1 - 1.9e-20 72.8 0.0 3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 EFI28156.1 - 0.0028 18.4 0.1 0.027 15.2 0.0 2.2 2 0 0 2 2 2 1 HIT domain DUF4922 PF16269.5 EFI28156.1 - 0.013 15.2 0.1 0.63 9.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) BAR_3 PF16746.5 EFI28157.1 - 0.0035 17.1 3.8 0.0048 16.6 3.8 1.1 1 0 0 1 1 1 1 BAR domain of APPL family EnY2 PF10163.9 EFI28157.1 - 0.075 13.4 3.4 0.56 10.6 4.0 2.1 2 0 0 2 2 2 0 Transcription factor e(y)2 ALMT PF11744.8 EFI28157.1 - 0.31 9.8 4.7 0.39 9.5 4.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter 2-Hacid_dh_C PF02826.19 EFI28158.1 - 1.5e-50 171.1 0.0 2e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EFI28158.1 - 3.9e-14 52.5 0.0 4.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EFI28158.1 - 0.00036 20.7 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C2H2 PF00096.26 EFI28160.1 - 6.7e-09 35.7 10.4 0.00011 22.5 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EFI28160.1 - 4.1e-07 30.3 5.2 0.008 16.9 1.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EFI28160.1 - 6e-06 26.4 12.6 7.3e-06 26.2 0.7 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EFI28160.1 - 0.00061 20.0 1.1 0.037 14.3 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EFI28160.1 - 0.0072 16.3 2.8 0.33 11.0 0.7 3.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EFI28160.1 - 0.01 15.6 1.0 5.4 6.9 0.3 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EFI28160.1 - 0.019 15.3 2.3 3.8 8.0 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type BolA PF01722.18 EFI28160.1 - 0.073 13.4 0.1 17 5.7 0.0 2.6 2 1 0 2 2 2 0 BolA-like protein zf-C2H2_3rep PF18868.1 EFI28160.1 - 0.083 13.6 0.2 0.29 11.8 0.1 1.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats TPR_1 PF00515.28 EFI28161.1 - 2.6e-15 55.5 1.9 0.00023 20.9 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EFI28161.1 - 3.4e-12 45.5 4.1 0.0047 16.9 0.5 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 EFI28161.1 - 2.5e-11 43.3 0.0 5.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.6 EFI28161.1 - 5.5e-10 38.7 0.8 0.00055 19.9 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EFI28161.1 - 4.9e-08 33.2 3.7 6.6e-06 26.3 0.5 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EFI28161.1 - 0.00038 20.1 0.5 0.033 13.9 0.0 3.8 3 1 2 5 5 5 1 TPR repeat TPR_10 PF13374.6 EFI28161.1 - 0.007 16.2 2.6 0.1 12.5 0.0 3.4 5 0 0 5 5 4 1 Tetratricopeptide repeat PFO_beta_C PF12367.8 EFI28161.1 - 0.0086 16.2 0.5 13 6.0 0.0 3.4 3 0 0 3 3 3 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal TPR_7 PF13176.6 EFI28161.1 - 0.01 15.8 7.8 0.29 11.3 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EFI28161.1 - 0.015 15.9 2.2 83 4.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Paf67 PF10255.9 EFI28161.1 - 0.04 12.9 0.2 0.058 12.4 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_17 PF13431.6 EFI28161.1 - 0.048 14.1 0.0 2 9.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EFI28161.1 - 0.049 14.3 3.4 1.1 10.0 0.1 3.2 3 1 1 4 4 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EFI28161.1 - 0.13 12.8 2.0 0.77 10.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Coilin_N PF15862.5 EFI28162.1 - 0.015 15.1 5.4 0.015 15.1 5.4 4.4 3 2 1 4 4 4 0 Coilin N-terminus Pro_CA PF00484.19 EFI28164.1 - 2.5e-28 99.3 0.0 4e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase DUF2407_C PF13373.6 EFI28165.1 - 1.9e-20 73.5 1.9 3.1e-20 72.8 0.7 2.0 2 1 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EFI28165.1 - 2.9e-12 47.1 0.0 1.7e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain VIT1 PF01988.19 EFI28165.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 VIT family DUF2855 PF11017.8 EFI28166.1 - 1.8e-107 360.0 0.0 2e-107 359.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) FGE-sulfatase PF03781.16 EFI28167.1 - 7.7e-23 81.4 0.4 2.1e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EFI28167.1 - 3.7e-07 30.7 0.2 7.5e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 DinB superfamily Ank_4 PF13637.6 EFI28169.1 - 8.4e-16 58.1 0.1 9.1e-08 32.5 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EFI28169.1 - 1.4e-14 54.4 0.0 9.6e-07 29.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EFI28169.1 - 5e-13 49.0 0.8 9.4e-05 22.6 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EFI28169.1 - 9.9e-13 47.9 3.3 1.7e-05 25.0 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EFI28169.1 - 1.2e-12 46.8 0.2 0.002 18.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Fe-S_biosyn PF01521.20 EFI28170.1 - 2.9e-13 50.0 0.0 4.2e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis FoP_duplication PF13865.6 EFI28172.1 - 4 8.1 12.0 6.3 7.4 12.0 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF218 PF02698.17 EFI28173.1 - 3.2e-06 27.2 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Med12-LCEWAV PF12145.8 EFI28176.1 - 0.00032 19.7 0.0 0.0016 17.3 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Med12 PF09497.10 EFI28177.1 - 3.9e-26 91.1 0.1 1e-25 89.7 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DASH_Dad2 PF08654.10 EFI28178.1 - 1.5e-07 31.7 0.4 2.8e-07 30.9 0.4 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 Peptidase_C25 PF01364.18 EFI28178.1 - 0.18 11.0 0.0 0.21 10.7 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C25 GIY-YIG PF01541.24 EFI28179.1 - 0.00016 21.9 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain HSP70 PF00012.20 EFI28180.1 - 2.3e-236 785.7 4.9 2.8e-236 785.4 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EFI28180.1 - 4.9e-21 74.9 1.3 2.8e-20 72.4 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 EFI28180.1 - 4.1e-05 23.0 0.1 8.7e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 StbA protein FtsA PF14450.6 EFI28180.1 - 0.00018 21.8 0.1 0.52 10.8 0.0 2.9 2 0 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.16 EFI28180.1 - 0.041 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Zincin_2 PF10103.9 EFI28180.1 - 0.073 12.3 0.0 0.57 9.4 0.0 2.0 2 0 0 2 2 2 0 Zincin-like metallopeptidase DDR PF08841.10 EFI28180.1 - 0.15 11.0 1.8 4.1 6.3 0.0 3.0 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain U3_assoc_6 PF08640.11 EFI28182.1 - 3e-30 104.1 6.1 7.8e-29 99.6 5.2 2.6 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EFI28182.1 - 5.8e-06 26.7 0.8 0.13 13.1 0.0 5.2 4 1 2 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EFI28182.1 - 0.0044 16.2 0.3 0.045 12.9 0.0 2.7 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 EFI28182.1 - 0.011 14.9 0.1 0.027 13.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Suf PF05843.14 EFI28182.1 - 0.039 13.9 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Arg_decarbox_C PF17944.1 EFI28182.1 - 0.74 10.4 4.5 2.2 8.9 0.6 3.3 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Ribosomal_S21 PF01165.20 EFI28182.1 - 2.9 7.7 6.6 4.4 7.1 0.4 3.1 3 0 0 3 3 3 0 Ribosomal protein S21 Med1 PF10744.9 EFI28184.1 - 8.3e-08 31.7 0.0 9.2e-05 21.7 0.0 2.3 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 MS_channel PF00924.18 EFI28185.1 - 1e-18 67.6 1.8 1.8e-18 66.8 1.8 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EFI28185.1 - 4.4e-06 25.8 0.2 1.4e-05 24.3 0.2 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EFI28185.1 - 1.4e-05 24.7 0.0 4.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EFI28185.1 - 0.0016 18.8 0.0 0.004 17.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EFI28185.1 - 0.0088 15.5 0.2 0.037 13.5 0.2 2.1 1 0 0 1 1 1 1 EF hand PBP1_TM PF14812.6 EFI28185.1 - 0.078 13.4 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2207 PF09972.9 EFI28185.1 - 0.22 10.3 1.3 0.8 8.4 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3098 PF11297.8 EFI28185.1 - 8.6 6.1 7.8 0.16 11.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) E3_UbLigase_R4 PF13764.6 EFI28186.1 - 0.024 12.8 0.2 0.033 12.4 0.2 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 FUSC PF04632.12 EFI28186.1 - 0.036 12.6 0.3 0.056 12.0 0.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1515 PF07439.11 EFI28186.1 - 0.092 12.8 0.5 0.18 11.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) GPS2_interact PF15784.5 EFI28186.1 - 0.13 12.7 1.8 0.54 10.7 1.8 2.1 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain tRNA-synt_1e PF01406.19 EFI28187.1 - 4.7e-113 377.5 0.0 8.3e-113 376.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EFI28187.1 - 1e-07 31.1 0.4 0.0014 17.5 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EFI28187.1 - 0.013 16.0 2.0 0.015 15.8 0.0 2.1 2 0 0 2 2 2 0 DALR domain Metallophos PF00149.28 EFI28188.1 - 2.1e-06 28.4 0.1 3.6e-06 27.6 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BLM10_N PF16547.5 EFI28189.1 - 0.14 12.4 1.3 0.51 10.7 1.3 1.9 1 1 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal SNF2_N PF00176.23 EFI28190.1 - 6.3e-55 186.3 0.0 9.7e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EFI28190.1 - 8.7e-14 51.8 0.0 1.7e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EFI28190.1 - 3.1e-10 40.3 0.0 1.8e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EFI28190.1 - 4.5e-07 29.8 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.9 EFI28190.1 - 1.9e-05 24.9 0.2 0.34 11.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2439) HDA2-3 PF11496.8 EFI28190.1 - 0.0098 15.1 0.0 0.043 13.0 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.9 EFI28190.1 - 0.11 11.7 0.8 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) HTH_WhiA PF02650.14 EFI28191.1 - 0.14 12.5 0.3 1.6 9.1 0.1 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain ABC_membrane PF00664.23 EFI28192.1 - 6.1e-36 124.5 3.1 9.1e-36 123.9 3.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EFI28192.1 - 1.4e-33 116.3 0.0 2.5e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EFI28192.1 - 2.9e-05 23.6 0.6 0.00052 19.5 0.6 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EFI28192.1 - 0.00059 20.3 0.1 0.0018 18.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EFI28192.1 - 0.0018 18.1 0.1 0.0053 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EFI28192.1 - 0.002 17.9 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EFI28192.1 - 0.004 16.9 0.2 0.0096 15.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.20 EFI28192.1 - 0.0067 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 EFI28192.1 - 0.012 15.8 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EFI28192.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 EFI28192.1 - 0.036 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 EFI28192.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DLIC PF05783.11 EFI28192.1 - 1.8 7.3 3.7 0.84 8.4 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) COG5 PF10392.9 EFI28193.1 - 2.8e-07 30.8 0.0 3.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DSPc PF00782.20 EFI28194.1 - 3.1e-07 30.3 0.0 1.4e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EFI28194.1 - 0.0012 18.4 0.2 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EFI28194.1 - 0.0013 18.8 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EFI28194.1 - 0.0075 15.9 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_2 PF07719.17 EFI28195.1 - 3.9e-25 85.9 41.3 0.00079 19.4 0.2 18.6 20 1 0 20 20 19 5 Tetratricopeptide repeat TPR_19 PF14559.6 EFI28195.1 - 6.1e-24 84.3 42.2 4.1e-06 27.2 0.4 13.2 12 2 4 16 16 14 7 Tetratricopeptide repeat TPR_1 PF00515.28 EFI28195.1 - 7.4e-23 79.4 23.5 0.00025 20.7 0.1 13.3 16 0 0 16 16 14 6 Tetratricopeptide repeat TPR_14 PF13428.6 EFI28195.1 - 9.2e-22 75.9 62.2 0.0022 18.7 0.5 18.2 12 6 7 19 19 19 3 Tetratricopeptide repeat TPR_8 PF13181.6 EFI28195.1 - 4.4e-18 63.9 21.3 0.0032 17.6 0.0 14.1 16 1 0 16 16 13 3 Tetratricopeptide repeat TPR_16 PF13432.6 EFI28195.1 - 9.6e-18 64.6 64.8 0.00011 22.8 2.5 13.4 15 2 2 17 17 13 6 Tetratricopeptide repeat TPR_17 PF13431.6 EFI28195.1 - 6.9e-17 60.5 7.1 0.0049 17.2 0.0 9.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EFI28195.1 - 1e-12 47.5 18.6 0.036 13.7 0.2 9.9 10 2 2 12 12 11 5 TPR repeat TPR_12 PF13424.6 EFI28195.1 - 3.5e-10 40.0 50.1 0.5 10.7 0.0 13.7 11 3 2 14 14 13 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EFI28195.1 - 9.2e-06 25.8 17.0 0.39 11.0 0.1 8.5 9 1 1 10 10 9 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EFI28195.1 - 3.8e-05 23.4 26.5 0.21 11.7 0.2 10.8 12 2 1 13 13 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 EFI28195.1 - 0.00027 21.0 33.6 0.074 13.2 0.8 9.0 9 1 0 9 9 8 2 Tetratricopeptide repeat RPN7 PF10602.9 EFI28195.1 - 0.00069 19.4 1.8 8.2 6.1 0.1 6.0 6 2 0 6 6 6 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 EFI28195.1 - 0.0014 19.2 32.1 1.5 9.6 0.1 12.1 14 0 0 14 14 10 1 Tetratricopeptide repeat FAT PF02259.23 EFI28195.1 - 0.0018 17.6 0.2 4.4 6.4 0.0 4.2 3 1 1 4 4 4 1 FAT domain NARP1 PF12569.8 EFI28195.1 - 0.0024 16.9 4.1 10 4.9 0.0 4.4 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 Coatomer_WDAD PF04053.14 EFI28195.1 - 0.0039 16.3 2.6 0.79 8.7 0.1 3.8 4 0 0 4 4 4 1 Coatomer WD associated region DUF3986 PF13143.6 EFI28195.1 - 0.048 14.6 0.0 0.14 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) TPR_20 PF14561.6 EFI28195.1 - 0.065 13.6 9.4 0.11 12.9 0.1 5.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EFI28195.1 - 0.091 12.9 6.3 4.3 7.5 0.0 5.1 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat HemY_N PF07219.13 EFI28195.1 - 0.21 11.8 0.1 0.21 11.8 0.1 4.4 6 0 0 6 6 3 0 HemY protein N-terminus HrpB1_HrpK PF09613.10 EFI28195.1 - 0.5 10.0 3.7 2.9 7.5 0.1 3.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC5 PF12862.7 EFI28195.1 - 0.51 10.4 6.5 4.7 7.4 0.0 4.6 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 Alkyl_sulf_dimr PF14863.6 EFI28195.1 - 0.95 9.9 5.3 11 6.5 0.2 4.3 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation eIF-3c_N PF05470.12 EFI28197.1 - 3.5e-175 583.7 25.0 3.8e-173 577.0 25.0 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EFI28197.1 - 1.2e-13 51.5 0.1 8.2e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 PCI domain CENP-B_dimeris PF09026.10 EFI28197.1 - 0.05 14.0 13.2 0.11 12.9 13.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EFI28197.1 - 0.32 10.3 8.2 0.61 9.3 8.2 1.4 1 0 0 1 1 1 0 NOA36 protein D123 PF07065.14 EFI28197.1 - 0.6 9.2 6.5 5.4 6.1 1.7 2.3 2 0 0 2 2 2 0 D123 Cwf_Cwc_15 PF04889.12 EFI28197.1 - 3.6 7.2 16.9 0.074 12.8 7.6 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GT87 PF09594.10 EFI28198.1 - 0.021 14.6 4.0 0.037 13.7 4.0 1.3 1 1 0 1 1 1 0 Glycosyltransferase family 87 MitoNEET_N PF10660.9 EFI28198.1 - 0.47 10.5 1.3 2.7 8.1 0.3 2.4 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF5353 PF17304.2 EFI28198.1 - 2.8 7.7 6.1 2.3 8.0 1.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5353) CAP_GLY PF01302.25 EFI28199.1 - 1.6e-19 69.6 1.1 3.5e-19 68.6 1.1 1.6 1 0 0 1 1 1 1 CAP-Gly domain Tropomyosin_1 PF12718.7 EFI28199.1 - 6.3e-05 23.1 6.0 6.3e-05 23.1 6.0 7.2 3 2 3 8 8 8 2 Tropomyosin like BST2 PF16716.5 EFI28199.1 - 0.00054 20.5 10.0 0.00054 20.5 10.0 8.7 3 3 4 7 7 7 1 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 EFI28199.1 - 0.00069 19.6 11.8 0.00069 19.6 11.8 8.6 6 2 2 9 9 9 4 TATA element modulatory factor 1 DNA binding CLIP1_ZNF PF16641.5 EFI28199.1 - 0.025 14.4 10.1 0.085 12.8 1.7 2.4 2 0 0 2 2 2 0 CLIP1 zinc knuckle zf-CCHC PF00098.23 EFI28199.1 - 0.089 12.9 5.1 0.38 10.9 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EFI28199.1 - 0.19 11.5 3.1 3.4 7.5 0.4 2.5 2 0 0 2 2 2 0 Zinc knuckle DUF4407 PF14362.6 EFI28199.1 - 1.7 8.0 66.5 0.55 9.5 6.3 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EFI28199.1 - 5.4 5.8 96.0 0.17 10.7 21.5 5.6 1 1 3 5 5 5 0 Spc7 kinetochore protein Ribosomal_S13 PF00416.22 EFI28200.1 - 1.3e-55 187.3 2.3 1.5e-55 187.1 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EFI28200.1 - 0.0044 15.8 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 EFI28200.1 - 0.035 14.4 0.1 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 Helix-hairpin-helix motif DUF2746 PF10874.8 EFI28200.1 - 0.059 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Ribosomal_L34 PF00468.17 EFI28201.1 - 4.7e-19 68.1 8.4 7.7e-19 67.4 8.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 UBA PF00627.31 EFI28203.1 - 8.1e-31 105.5 3.7 2.3e-14 53.0 0.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EFI28203.1 - 5.5e-21 74.1 0.8 8.4e-21 73.5 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 EFI28203.1 - 3e-15 55.7 10.4 3e-15 55.7 10.4 1.8 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 EFI28203.1 - 6.6e-06 25.9 0.8 1e-05 25.2 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EFI28203.1 - 0.0024 18.2 0.3 0.0043 17.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2999 PF11212.8 EFI28203.1 - 0.0041 17.3 1.3 0.065 13.5 1.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2999) Rad60-SLD_2 PF13881.6 EFI28203.1 - 0.0076 16.3 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 EFI28203.1 - 0.0091 15.7 0.0 1.6 8.5 0.0 2.9 2 1 0 2 2 2 1 CUE domain UBA_3 PF09288.10 EFI28203.1 - 0.011 15.5 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF1421 PF07223.11 EFI28203.1 - 0.012 15.5 0.0 0.1 12.5 0.1 2.2 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Ubiquitin_2 PF14560.6 EFI28203.1 - 0.024 15.1 0.2 0.042 14.3 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Acetyltransf_17 PF17668.1 EFI28203.1 - 0.054 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain STI1 PF17830.1 EFI28203.1 - 0.062 13.2 5.0 1.2 9.1 5.0 2.6 1 1 0 1 1 1 0 STI1 domain WIYLD PF10440.9 EFI28203.1 - 0.15 11.9 0.0 22 4.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF3391 PF11871.8 EFI28203.1 - 0.25 11.9 3.8 6 7.4 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) PLA2_B PF01735.18 EFI28204.1 - 6.8e-97 324.9 0.0 8.7e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF2207 PF09972.9 EFI28204.1 - 0.2 10.4 0.2 0.65 8.7 0.0 1.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Yippee-Mis18 PF03226.14 EFI28205.1 - 4.5e-09 36.5 0.0 7.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.6 EFI28205.1 - 0.056 13.3 0.4 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease DUF169 PF02596.15 EFI28205.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 GPI-anchored PF10342.9 EFI28206.1 - 0.0019 18.9 0.0 0.0027 18.4 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NDUF_B12 PF08122.12 EFI28207.1 - 2.7e-22 78.5 0.2 3.2e-22 78.3 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Cation_ATPase_C PF00689.21 EFI28207.1 - 0.033 13.9 0.0 0.033 13.9 0.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus MipZ PF09140.11 EFI28207.1 - 0.035 13.4 0.0 0.039 13.2 0.0 1.0 1 0 0 1 1 1 0 ATPase MipZ PHD PF00628.29 EFI28208.1 - 1.9e-11 43.7 9.8 3.1e-11 43.0 9.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EFI28208.1 - 0.0053 16.4 4.2 0.011 15.3 4.2 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-CW PF07496.15 EFI28208.1 - 0.038 14.0 1.4 0.08 13.0 1.4 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 EFI28208.1 - 0.42 10.2 6.8 0.74 9.4 6.8 1.4 1 0 0 1 1 1 0 PHD-finger AAA_12 PF13087.6 EFI28211.1 - 6.4e-17 61.8 0.0 1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EFI28211.1 - 4.6e-08 32.8 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF4825 PF16107.5 EFI28211.1 - 0.18 12.0 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4825) LCM PF04072.14 EFI28212.1 - 2e-13 50.7 0.0 3.5e-08 33.6 0.0 2.9 3 2 0 3 3 3 2 Leucine carboxyl methyltransferase MPTase-PolyVal PF18818.1 EFI28213.1 - 0.0018 18.3 2.8 0.0048 17.0 2.8 1.8 1 1 0 1 1 1 1 Metallopeptidase superfamily domain MAGE_N PF12440.8 EFI28213.1 - 0.016 15.9 0.5 0.016 15.9 0.5 2.6 2 1 0 2 2 2 0 Melanoma associated antigen family N terminal PH PF00169.29 EFI28214.1 - 6e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_12 PF16457.5 EFI28214.1 - 0.17 12.4 0.3 0.43 11.1 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Pheromone PF08015.11 EFI28215.1 - 3.3e-05 24.8 0.9 0.0011 20.0 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pkinase PF00069.25 EFI28216.1 - 2.3e-47 161.6 0.0 1.6e-19 70.3 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28216.1 - 4.9e-30 104.7 0.0 3.1e-24 85.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI28216.1 - 0.032 13.0 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EFI28216.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EFI28216.1 - 0.17 11.1 0.0 7 5.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pheromone PF08015.11 EFI28217.1 - 1.4e-06 29.2 1.0 2.7e-05 25.1 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI28218.1 - 8.4e-07 29.9 1.7 2.4e-05 25.3 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pkinase PF00069.25 EFI28220.1 - 1.6e-52 178.5 0.0 2.6e-52 177.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28220.1 - 2e-21 76.4 0.0 3.3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EFI28220.1 - 4.4e-05 23.5 0.1 4.4e-05 23.5 0.1 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EFI28220.1 - 0.0025 17.4 0.4 0.0048 16.5 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EFI28220.1 - 0.059 13.0 0.3 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase CASP_C PF08172.12 EFI28221.1 - 2.4e-78 263.0 0.9 2.4e-78 263.0 0.9 4.0 2 1 1 3 3 3 1 CASP C terminal KLRAQ PF10205.9 EFI28221.1 - 0.0017 18.6 1.3 0.0017 18.6 1.3 6.2 3 2 3 6 6 6 1 Predicted coiled-coil domain-containing protein CtIP_N PF10482.9 EFI28221.1 - 0.023 14.7 2.1 0.023 14.7 2.1 5.5 4 1 1 5 5 5 0 Tumour-suppressor protein CtIP N-terminal domain FlaC_arch PF05377.11 EFI28221.1 - 0.13 12.7 49.2 2.3 8.7 0.1 8.6 8 1 0 8 8 8 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EFI28221.1 - 3.6 8.0 60.2 0.91 9.9 21.7 4.4 1 1 3 4 4 4 0 Fez1 TMEM192 PF14802.6 EFI28221.1 - 6.2 5.9 8.7 9.3 5.3 0.1 3.3 3 0 0 3 3 3 0 TMEM192 family Methyltransf_31 PF13847.6 EFI28223.1 - 3.3e-06 27.0 0.0 7.2e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EFI28223.1 - 7.5e-05 22.3 0.1 0.00054 19.6 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EFI28223.1 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EFI28223.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EFI28223.1 - 0.00051 19.9 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EFI28223.1 - 0.024 15.3 0.0 0.043 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 EFI28223.1 - 0.068 12.4 0.0 0.088 12.1 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Pyrid_ox_like PF16242.5 EFI28225.1 - 1.6e-30 105.7 0.0 2.5e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EFI28225.1 - 6.8e-13 48.6 0.0 2.9e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase GDP_Man_Dehyd PF16363.5 EFI28225.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CRAL_TRIO PF00650.20 EFI28227.1 - 2.4e-10 40.4 0.0 3.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Kelch_3 PF13415.6 EFI28228.1 - 0.13 12.6 0.3 0.33 11.3 0.1 1.8 2 0 0 2 2 2 0 Galactose oxidase, central domain GCP_C_terminal PF04130.13 EFI28230.1 - 5.1e-58 197.0 0.0 1.1e-57 195.8 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EFI28230.1 - 3.8e-07 30.0 0.0 8.8e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal Peptidase_M36 PF02128.15 EFI28231.1 - 2e-116 389.2 0.0 2.4e-116 388.9 0.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EFI28231.1 - 1.4e-06 28.0 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif PH_10 PF15411.6 EFI28234.1 - 2.1e-36 124.9 0.0 4.2e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EFI28234.1 - 3.7e-29 102.2 0.2 5.9e-29 101.6 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EFI28234.1 - 8.7e-16 57.6 0.0 1.6e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 EFI28234.1 - 7.2e-09 35.8 0.1 1.3e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 CDC24 Calponin Rap_GAP PF02145.15 EFI28234.1 - 0.077 12.5 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Rap/ran-GAP Ephrin_rec_like PF07699.13 EFI28235.1 - 3.2e-07 30.0 49.0 0.00046 19.9 8.0 5.6 4 2 2 6 6 6 3 Putative ephrin-receptor like DUF3435 PF11917.8 EFI28236.1 - 0.09 11.7 2.4 0.13 11.2 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) ISG65-75 PF11727.8 EFI28236.1 - 0.53 9.5 4.1 0.89 8.7 4.1 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein KI67R PF08065.12 EFI28236.1 - 2.2 8.8 7.2 3.9 8.0 2.3 2.4 2 0 0 2 2 2 0 KI67R (NUC007) repeat LRR_6 PF13516.6 EFI28237.1 - 0.048 13.7 0.1 0.69 10.1 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich repeat Gram_pos_anchor PF00746.21 EFI28241.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Tetraspanin PF00335.20 EFI28246.1 - 5.7 6.6 7.2 39 3.8 5.2 2.1 1 1 1 2 2 2 0 Tetraspanin family CE2_N PF17996.1 EFI28247.1 - 0.0022 17.9 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal HSP70 PF00012.20 EFI28249.1 - 5.9e-05 21.5 0.0 0.00011 20.6 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.25 EFI28249.1 - 0.032 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family DDR PF08841.10 EFI28249.1 - 0.088 11.8 0.1 4.9 6.0 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain MreB_Mbl PF06723.13 EFI28249.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein Exo_endo_phos PF03372.23 EFI28250.1 - 7.5e-25 87.8 0.1 3.1e-23 82.5 0.1 2.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EFI28250.1 - 1.1e-15 57.1 21.0 1.5e-07 31.0 3.9 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EFI28250.1 - 2.2e-11 43.8 5.2 3.5e-05 24.1 1.9 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EFI28250.1 - 0.0063 16.9 5.2 11 7.0 0.5 5.5 3 1 1 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 EFI28250.1 - 0.33 11.1 1.5 9.8 6.5 0.3 3.2 3 0 0 3 3 3 0 Leucine Rich repeat MBOAT_2 PF13813.6 EFI28251.1 - 1.4e-24 86.2 4.8 3.2e-24 85.0 4.8 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ribosomal_L39 PF00832.20 EFI28255.1 - 2.4e-23 81.5 10.0 2.8e-23 81.2 10.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 EFI28255.1 - 0.017 14.7 0.4 0.017 14.7 0.4 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 DUF2316 PF10078.9 EFI28256.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Ank_2 PF12796.7 EFI28257.1 - 7e-77 254.1 3.7 1.9e-11 44.4 0.0 8.6 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EFI28257.1 - 2.1e-50 162.8 16.5 0.0036 17.7 0.0 16.3 16 0 0 16 16 16 12 Ankyrin repeat Ank PF00023.30 EFI28257.1 - 4.1e-47 156.7 28.9 0.0023 18.3 0.0 16.2 16 0 0 16 16 16 13 Ankyrin repeat Ank_4 PF13637.6 EFI28257.1 - 5e-43 145.0 13.9 2.4e-06 28.0 0.0 12.5 3 3 8 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 EFI28257.1 - 1.1e-34 118.0 31.8 3.6e-05 24.0 0.2 12.1 5 3 8 13 13 13 9 Ankyrin repeats (many copies) Se-cys_synth_N PF12390.8 EFI28257.1 - 0.02 15.1 2.1 7.8 6.8 0.0 5.8 4 1 0 4 4 4 0 Selenocysteine synthase N terminal DUF348 PF03990.14 EFI28257.1 - 0.12 12.1 0.6 15 5.5 0.0 3.9 5 0 0 5 5 5 0 G5-linked-Ubiquitin-like domain NOG1_N PF17835.1 EFI28261.1 - 6e-49 166.1 0.5 6e-49 166.1 0.5 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EFI28261.1 - 4e-28 97.0 0.1 8.6e-28 95.9 0.1 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EFI28261.1 - 1.4e-27 95.4 1.1 3.5e-27 94.1 1.1 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EFI28261.1 - 8e-18 64.6 0.0 2.7e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EFI28261.1 - 5.8e-11 42.2 0.0 1.5e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EFI28261.1 - 0.001 19.0 0.2 0.78 9.6 0.0 3.6 4 1 0 4 4 4 1 RsgA GTPase Dynamin_N PF00350.23 EFI28261.1 - 0.0081 16.2 0.9 1.8 8.6 0.0 2.9 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 EFI28261.1 - 0.019 15.2 0.0 0.15 12.3 0.0 2.3 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Sushi_2 PF09014.10 EFI28261.1 - 0.081 12.8 0.2 0.19 11.6 0.2 1.6 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain AIG1 PF04548.16 EFI28261.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family DUF494 PF04361.13 EFI28261.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF494) G-alpha PF00503.20 EFI28261.1 - 0.091 11.9 0.6 2.3 7.3 0.1 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AAA_16 PF13191.6 EFI28261.1 - 0.1 13.0 0.1 0.67 10.3 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain DDHD PF02862.17 EFI28266.1 - 0.14 12.3 1.1 0.16 12.1 1.1 1.1 1 0 0 1 1 1 0 DDHD domain TRAP_alpha PF03896.16 EFI28266.1 - 0.17 11.0 3.4 0.22 10.7 3.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MDM1 PF15501.6 EFI28266.1 - 0.2 10.8 13.6 0.22 10.6 13.6 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Rrn6 PF10214.9 EFI28266.1 - 0.25 9.8 9.8 0.28 9.6 9.8 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RR_TM4-6 PF06459.12 EFI28266.1 - 0.3 10.9 8.3 0.35 10.7 8.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EFI28266.1 - 0.36 9.1 9.3 0.36 9.1 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein HAUS6_N PF14661.6 EFI28266.1 - 0.46 10.0 7.8 0.6 9.7 7.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2252 PF10009.9 EFI28266.1 - 0.65 9.0 6.8 0.83 8.6 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4207 PF13904.6 EFI28266.1 - 0.71 9.5 19.4 1 9.0 19.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) AAA_11 PF13086.6 EFI28266.1 - 1.7 8.4 6.2 2.1 8.1 6.2 1.1 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EFI28266.1 - 1.8 7.2 6.7 1.9 7.2 6.7 1.1 1 0 0 1 1 1 0 Presenilin DUF1266 PF06889.11 EFI28266.1 - 2.4 8.2 12.1 3.4 7.7 11.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) DUF2407_C PF13373.6 EFI28266.1 - 4.4 7.5 8.0 6.6 6.9 8.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF4746 PF15928.5 EFI28266.1 - 4.9 6.5 14.5 6 6.2 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DinB PF05163.12 EFI28266.1 - 7.3 6.5 10.6 19 5.1 10.6 1.6 1 1 0 1 1 1 0 DinB family Macoilin PF09726.9 EFI28266.1 - 7.4 5.0 13.5 8.5 4.8 13.5 1.0 1 0 0 1 1 1 0 Macoilin family RPN2_C PF18004.1 EFI28266.1 - 8.2 6.3 11.3 12 5.8 11.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain IF4E PF01652.18 EFI28267.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E rve PF00665.26 EFI28269.1 - 1.8e-07 31.4 0.0 2.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain VD10_N PF08476.10 EFI28269.1 - 0.0091 15.6 0.1 0.25 11.0 0.0 2.3 2 0 0 2 2 2 1 Viral D10 N-terminal HTH_23 PF13384.6 EFI28269.1 - 0.014 15.2 0.6 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_40 PF14493.6 EFI28269.1 - 0.022 15.2 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 EFI28269.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.18 EFI28269.1 - 0.075 13.3 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Transposase HTH_11 PF08279.12 EFI28269.1 - 0.17 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 HTH domain PX PF00787.24 EFI28271.1 - 1.9e-25 89.1 0.0 2.1e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 PX domain Plavaka PF18759.1 EFI28273.1 - 3.3e-128 427.5 0.0 4.7e-128 427.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase CENP-B_dimeris PF09026.10 EFI28273.1 - 2.1 8.8 7.8 5.3 7.5 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Plavaka PF18759.1 EFI28274.1 - 3.3e-128 427.5 0.0 4.7e-128 427.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase CENP-B_dimeris PF09026.10 EFI28274.1 - 2.1 8.8 7.8 5.3 7.5 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Alpha_kinase PF02816.18 EFI28277.1 - 1.7e-14 54.4 0.0 3.6e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 Alpha-kinase family FYDLN_acid PF09538.10 EFI28277.1 - 0.12 13.0 0.9 0.33 11.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-C3HC4_3 PF13920.6 EFI28277.1 - 0.18 11.7 2.1 0.6 10.0 2.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 EFI28277.1 - 5.3 7.3 7.4 6.1 7.0 4.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Defensin_5 PF18251.1 EFI28284.1 - 5e-31 106.5 34.1 2.3e-20 72.4 16.1 2.8 2 0 0 2 2 2 2 Fungal defensin Copsin CFEM PF05730.11 EFI28284.1 - 1.4e-07 31.5 20.6 8.5e-06 25.8 5.5 3.5 4 0 0 4 4 4 2 CFEM domain XRN_M PF17846.1 EFI28285.1 - 0.85 8.5 5.7 1 8.2 5.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF4820 PF16091.5 EFI28285.1 - 0.86 8.9 8.7 1.3 8.4 8.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) AP_endonuc_2 PF01261.24 EFI28286.1 - 5.3e-22 78.3 0.0 3.2e-12 46.3 0.0 2.1 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel DUF2124 PF09897.9 EFI28286.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) ATP-synt_Eps PF04627.13 EFI28288.1 - 1.5e-19 69.7 5.1 5.3e-19 67.9 2.8 2.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain NACHT PF05729.12 EFI28288.1 - 1.1e-07 32.0 0.1 4.3e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 NACHT domain TPR_12 PF13424.6 EFI28288.1 - 7.4e-06 26.2 24.6 3.9 7.8 0.3 10.4 7 3 4 12 12 11 2 Tetratricopeptide repeat TPR_10 PF13374.6 EFI28288.1 - 1.6e-05 24.6 29.7 3 7.8 0.0 11.5 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 EFI28288.1 - 0.00014 21.7 7.8 6.3 7.1 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat AAA_16 PF13191.6 EFI28288.1 - 0.0019 18.6 0.8 0.025 15.0 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 EFI28288.1 - 0.003 16.6 0.1 0.0092 15.0 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EFI28288.1 - 0.0084 15.3 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 EFI28288.1 - 0.012 16.0 0.0 0.043 14.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase TPR_14 PF13428.6 EFI28288.1 - 0.019 15.8 21.2 83 4.4 0.1 10.0 10 1 1 11 11 8 0 Tetratricopeptide repeat AAA PF00004.29 EFI28288.1 - 0.065 13.7 0.1 1.5 9.2 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EFI28288.1 - 0.081 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain PNPase PF03726.14 EFI28288.1 - 0.61 10.6 2.7 22 5.6 0.0 4.1 3 1 1 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain MFS_1 PF07690.16 EFI28289.1 - 4.5e-06 25.8 48.0 2.2e-05 23.5 27.6 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Hydrophobin PF01185.18 EFI28293.1 - 3.7e-20 72.4 10.6 8.3e-20 71.2 10.6 1.6 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.7 EFI28293.1 - 8.8e-05 22.3 1.8 8.8e-05 22.3 1.8 1.9 2 0 0 2 2 2 1 F-box-like LDB19 PF13002.7 EFI28293.1 - 9e-05 22.3 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EFI28293.1 - 0.0024 17.9 0.0 0.0067 16.5 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain FTA4 PF13093.6 EFI28293.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TAL_effector PF03377.13 EFI28294.1 - 0.13 12.6 0.3 0.27 11.6 0.3 1.5 1 0 0 1 1 1 0 TAL effector repeat 3-PAP PF12578.8 EFI28294.1 - 1.5 8.6 4.3 1.3 8.8 0.1 2.3 2 1 0 2 2 2 0 Myotubularin-associated protein Syndecan PF01034.20 EFI28295.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain HemX PF04375.14 EFI28295.1 - 0.051 12.9 6.0 0.076 12.3 6.0 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4407 PF14362.6 EFI28295.1 - 0.11 11.8 2.7 0.17 11.2 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CASP_C PF08172.12 EFI28295.1 - 4.7 6.5 9.4 0.091 12.1 1.2 2.0 2 0 0 2 2 2 0 CASP C terminal SlyX PF04102.12 EFI28295.1 - 5.1 7.8 8.9 1.1 9.9 0.4 2.4 1 1 1 2 2 2 0 SlyX Di19_C PF14571.6 EFI28296.1 - 0.053 14.1 1.4 0.073 13.6 1.4 1.3 1 1 0 1 1 1 0 Stress-induced protein Di19, C-terminal Vma12 PF11712.8 EFI28298.1 - 6.3 6.9 10.6 31 4.6 0.9 3.2 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2070 PF09843.9 EFI28298.1 - 7.5 4.7 11.4 11 4.1 11.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) KDZ PF18758.1 EFI28299.1 - 6.5e-44 150.2 0.6 1.1e-43 149.5 0.6 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI28299.1 - 1.1e-19 70.5 0.0 2.6e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases CxC1 PF18802.1 EFI28299.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CCB1 PF12046.8 EFI28299.1 - 0.028 13.8 0.1 0.068 12.5 0.0 1.6 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B F-box-like PF12937.7 EFI28300.1 - 0.0055 16.6 0.1 0.023 14.6 0.1 2.2 1 0 0 1 1 1 1 F-box-like zf-C3HC4_3 PF13920.6 EFI28300.1 - 0.85 9.5 2.7 1.4 8.8 2.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAP_assoc PF03828.19 EFI28302.1 - 4.2e-17 62.1 1.4 8.6e-17 61.1 0.1 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EFI28302.1 - 5.9e-10 39.3 0.0 1.5e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EFI28302.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Dicty_CTDC PF00526.18 EFI28309.1 - 0.08 12.9 0.3 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat CE2_N PF17996.1 EFI28314.1 - 0.00057 19.8 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Trypan_PARP PF05887.11 EFI28314.1 - 3.2 7.7 10.1 2.5 8.1 3.5 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CE2_N PF17996.1 EFI28315.1 - 0.0015 18.5 0.0 0.59 10.2 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Gram_pos_anchor PF00746.21 EFI28315.1 - 0.03 14.3 7.2 0.12 12.3 7.2 1.9 1 1 0 1 1 1 0 LPXTG cell wall anchor motif AAA_2 PF07724.14 EFI28317.1 - 4.3e-10 40.0 0.0 8.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EFI28317.1 - 1.2e-09 38.3 0.0 2.4e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EFI28317.1 - 6.8e-05 23.3 0.0 0.00018 21.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EFI28317.1 - 0.0016 18.8 0.0 0.017 15.5 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EFI28317.1 - 0.021 15.1 0.0 0.11 12.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EFI28317.1 - 0.022 14.8 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EFI28317.1 - 0.033 14.6 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EFI28317.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EFI28317.1 - 0.14 11.5 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.11 EFI28317.1 - 0.15 11.0 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain AAA_33 PF13671.6 EFI28317.1 - 0.16 12.1 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SH3_1 PF00018.28 EFI28319.1 - 3.6e-07 29.7 0.0 6.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EFI28319.1 - 4.8e-06 26.3 0.0 7.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EFI28319.1 - 3.3e-05 23.5 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 EFI28319.1 - 0.0066 16.9 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Helically-extended SH3 domain Dapper PF15268.6 EFI28322.1 - 0.0047 15.9 0.1 0.0047 15.9 0.1 1.9 1 1 1 2 2 2 1 Dapper DUF2561 PF10812.8 EFI28322.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Glyco_hydro_85 PF03644.13 EFI28323.1 - 3e-70 237.0 0.0 4.1e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 SCP_3 PF17844.1 EFI28324.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial SCP ortholog Memo PF01875.17 EFI28324.1 - 0.02 14.0 0.3 5.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Memo-like protein GFD1 PF17331.2 EFI28324.1 - 0.04 14.1 0.5 0.11 12.7 0.5 1.7 1 0 0 1 1 1 0 GFD1 mRNA transport factor Proteasome PF00227.26 EFI28325.1 - 1.5e-49 168.1 0.1 1.8e-49 167.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit hSac2 PF12456.8 EFI28327.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Inositol phosphatase Syja_N PF02383.18 EFI28328.1 - 2.7e-82 276.7 0.0 3.8e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EFI28328.1 - 1.8e-09 37.3 0.1 5.8e-09 35.7 0.0 2.0 2 0 0 2 2 2 1 Inositol phosphatase MFS_1 PF07690.16 EFI28330.1 - 1.7e-40 139.1 72.4 2.6e-18 66.1 18.9 4.1 4 0 0 4 4 4 4 Major Facilitator Superfamily WD40 PF00400.32 EFI28331.1 - 1.6e-39 133.1 26.0 2.1e-05 25.2 0.3 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EFI28331.1 - 1.3e-05 24.1 7.8 0.1 11.2 0.1 5.1 3 1 3 6 6 6 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EFI28331.1 - 4.2e-05 23.8 0.8 2.1 8.7 0.0 5.3 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EFI28331.1 - 0.0066 15.4 6.7 0.84 8.5 0.5 4.3 2 1 3 5 5 5 3 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 EFI28331.1 - 0.018 13.8 0.2 0.35 9.6 0.1 3.1 3 1 1 4 4 4 0 Nup133 N terminal like Tyr_Deacylase PF02580.16 EFI28332.1 - 4.1e-55 186.3 0.1 4.7e-55 186.1 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ala_racemase_C PF00842.21 EFI28332.1 - 0.14 12.0 0.3 0.21 11.4 0.3 1.2 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Tim54 PF11711.8 EFI28335.1 - 1.1e-63 215.3 0.8 5.9e-63 212.9 0.8 1.9 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Remorin_C PF03763.13 EFI28335.1 - 0.0031 17.4 0.9 0.007 16.2 0.9 1.6 1 0 0 1 1 1 1 Remorin, C-terminal region VP9 PF09625.10 EFI28335.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 VP9 protein Peptidase_M22 PF00814.25 EFI28336.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family DDR PF08841.10 EFI28336.1 - 0.26 10.2 0.4 7.2 5.5 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain SKIP_SNW PF02731.15 EFI28337.1 - 7.2e-73 243.6 1.1 7.2e-73 243.6 1.1 2.3 2 0 0 2 2 2 1 SKIP/SNW domain PI3K_1B_p101 PF10486.9 EFI28337.1 - 2.4 5.8 9.9 3.7 5.2 9.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4603 PF15376.6 EFI28337.1 - 3.2 5.0 10.9 4.4 4.6 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Cwf_Cwc_15 PF04889.12 EFI28337.1 - 9.9 5.8 24.7 0.29 10.8 18.4 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Hydrolase_4 PF12146.8 EFI28338.1 - 1.2e-12 47.6 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EFI28338.1 - 1.5e-11 44.4 0.0 1.7e-09 37.7 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EFI28338.1 - 4.8e-10 40.4 0.0 7.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EFI28338.1 - 0.0016 18.2 0.1 0.0027 17.5 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 EFI28338.1 - 0.0033 17.3 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1100 PF06500.11 EFI28338.1 - 0.013 14.3 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) FSH1 PF03959.13 EFI28338.1 - 0.12 12.0 0.0 0.61 9.7 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2048 PF09752.9 EFI28338.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DUF676 PF05057.14 EFI28338.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.18 EFI28338.1 - 0.2 11.2 0.0 0.46 10.0 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF915 PF06028.11 EFI28338.1 - 0.27 10.6 0.0 0.88 8.9 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_transf_22 PF03901.17 EFI28339.1 - 4.9e-59 200.6 12.6 6.3e-59 200.3 12.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_44 PF12891.7 EFI28340.1 - 7e-71 238.9 1.8 1.1e-70 238.2 1.8 1.3 1 0 0 1 1 1 1 Glycoside hydrolase family 44 Trp_syntA PF00290.20 EFI28341.1 - 1.5e-85 286.2 0.8 2.2e-85 285.6 0.8 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EFI28341.1 - 6.3e-44 150.6 0.1 9e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 EFI28341.1 - 0.00011 21.7 0.1 0.00028 20.4 0.1 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 EFI28341.1 - 0.047 13.1 0.4 0.085 12.2 0.4 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Sulf_transp PF04143.14 EFI28343.1 - 2.9e-10 40.2 19.1 2.4e-08 33.9 9.1 2.7 2 0 0 2 2 2 2 Sulphur transport DUF726 PF05277.12 EFI28344.1 - 5.3e-90 301.8 1.2 7e-90 301.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Cutinase PF01083.22 EFI28344.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.7 EFI28344.1 - 0.036 14.7 0.1 0.1 13.2 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family JmjC PF02373.22 EFI28345.1 - 1.6e-12 47.9 0.0 3.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase K_oxygenase PF13434.6 EFI28346.1 - 7.3e-11 41.8 0.0 2.5e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EFI28346.1 - 9.5e-11 40.8 0.1 5.9e-10 38.2 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EFI28346.1 - 3.9e-05 23.0 0.0 0.00024 20.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EFI28346.1 - 0.013 14.7 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Flag1_repress PF03614.13 EFI28346.1 - 0.12 12.1 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Scm3 PF10384.9 EFI28346.1 - 0.23 11.2 1.0 0.69 9.7 1.0 1.8 1 0 0 1 1 1 0 Centromere protein Scm3 FRG1 PF06229.12 EFI28349.1 - 7.6e-29 100.8 0.2 7.6e-29 100.8 0.2 1.5 2 0 0 2 2 2 1 FRG1-like domain Fascin PF06268.13 EFI28349.1 - 0.00042 20.5 0.0 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 Fascin domain BRF1 PF07741.13 EFI28349.1 - 1.7 9.0 12.1 23 5.4 7.9 2.5 2 1 0 2 2 2 0 Brf1-like TBP-binding domain UCH PF00443.29 EFI28350.1 - 7.5e-14 51.8 0.1 8.3e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EFI28350.1 - 1.7e-11 44.3 0.0 2.1e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zinc_ribbon_10 PF10058.9 EFI28350.1 - 0.079 12.7 0.1 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein SAICAR_synt PF01259.18 EFI28351.1 - 0.043 13.4 0.2 0.08 12.5 0.2 1.4 1 1 0 1 1 1 0 SAICAR synthetase Med9 PF07544.13 EFI28351.1 - 0.065 13.3 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 RdRP PF05183.12 EFI28352.1 - 1.2e-175 585.5 0.0 1.7e-175 585.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Na_Ca_ex PF01699.24 EFI28352.1 - 4.2e-41 140.4 32.0 1.4e-21 77.1 12.8 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PI3_PI4_kinase PF00454.27 EFI28353.1 - 2.5e-27 96.3 0.0 9.3e-25 87.9 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EFI28353.1 - 5.2e-21 74.9 0.0 1.5e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ATP-synt_B PF00430.18 EFI28355.1 - 5.3 7.1 14.9 1.9 8.6 7.6 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF4200 PF13863.6 EFI28355.1 - 7.4 7.0 12.2 0.47 10.9 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Thioredoxin PF00085.20 EFI28356.1 - 1.1e-23 83.2 0.0 1.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EFI28356.1 - 7.9e-09 35.9 0.1 2.4e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EFI28356.1 - 1e-06 29.0 0.0 0.00081 19.7 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 EFI28356.1 - 0.00017 21.3 0.1 0.00074 19.2 0.1 1.7 1 1 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 EFI28356.1 - 0.0048 16.8 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EFI28356.1 - 0.006 16.4 0.0 0.0076 16.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EFI28356.1 - 0.009 16.2 0.1 0.033 14.4 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EFI28356.1 - 0.012 15.5 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein ERp29_N PF07912.13 EFI28356.1 - 0.012 15.8 0.0 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 ERp29, N-terminal domain KH_8 PF17903.1 EFI28357.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain Thiamine_BP PF01910.17 EFI28360.1 - 3e-27 94.3 0.0 3.8e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Thiamine-binding protein PIF1 PF05970.14 EFI28361.1 - 1.3e-23 83.8 0.0 1e-22 80.8 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EFI28361.1 - 1.6e-11 44.3 0.0 4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EFI28361.1 - 3.4e-06 27.4 0.0 9.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Helitron_like_N PF14214.6 EFI28361.1 - 9.4e-05 22.7 0.1 0.00027 21.2 0.1 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus HUN PF08729.10 EFI28361.1 - 0.023 14.7 8.1 0.01 15.8 4.5 2.3 2 0 0 2 2 2 0 HPC2 and ubinuclein domain TrwB_AAD_bind PF10412.9 EFI28361.1 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Spc7 PF08317.11 EFI28361.1 - 0.14 11.0 5.9 0.3 9.9 5.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein LRR_6 PF13516.6 EFI28364.1 - 0.11 12.6 0.0 20 5.6 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich repeat Rrn6 PF10214.9 EFI28365.1 - 0.00012 20.7 14.4 0.003 16.1 7.2 3.7 3 1 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor DUF1324 PF07038.11 EFI28365.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) Dmrt1 PF12374.8 EFI28365.1 - 6.5 7.3 7.0 0.79 10.2 0.2 2.6 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Mito_carr PF00153.27 EFI28366.1 - 9e-46 153.7 1.7 2.4e-15 56.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein MaoC_dehydratas PF01575.19 EFI28367.1 - 0.015 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 MaoC like domain DAGK_cat PF00781.24 EFI28368.1 - 4.3e-28 97.4 0.1 7.5e-28 96.7 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 EFI28368.1 - 0.0032 16.3 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Hexokinase_1 PF00349.21 EFI28368.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Hexokinase Nucleoporin_C PF03177.14 EFI28369.1 - 8.3e-87 292.3 0.8 1.2e-86 291.8 0.8 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EFI28369.1 - 2.6e-20 72.6 0.1 3.9e-20 72.0 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Methyltransf_11 PF08241.12 EFI28369.1 - 8.1e-15 55.3 0.0 2.6e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EFI28369.1 - 9.3e-11 42.3 0.0 2.6e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EFI28369.1 - 6e-06 26.9 0.0 1.8e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EFI28369.1 - 9.9e-05 22.2 0.0 0.00025 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EFI28369.1 - 0.00084 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 EFI28369.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RPA_C PF08784.11 EFI28370.1 - 4e-13 49.9 0.1 1.1e-12 48.5 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EFI28370.1 - 3.6e-06 26.9 0.1 6.2e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EFI28370.1 - 0.0008 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti_2 PF13742.6 EFI28370.1 - 0.046 13.9 0.2 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain MarR_2 PF12802.7 EFI28370.1 - 0.11 12.4 0.1 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 MarR family tRNA_anti-codon PF01336.25 EFI28371.1 - 3e-07 30.3 0.1 5.6e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 EFI28371.1 - 1.2e-06 29.1 0.1 6.3e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti_2 PF13742.6 EFI28371.1 - 9.2e-05 22.6 0.3 0.00043 20.4 0.1 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Coatomer_WDAD PF04053.14 EFI28371.1 - 0.16 11.0 0.1 0.21 10.6 0.1 1.1 1 0 0 1 1 1 0 Coatomer WD associated region DUF1589 PF07628.11 EFI28373.1 - 0.011 15.9 1.1 0.015 15.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) Tudor_3 PF18115.1 EFI28374.1 - 7.1e-07 29.0 0.1 1.9e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EFI28374.1 - 3e-05 24.0 0.0 6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) BRCT_2 PF16589.5 EFI28374.1 - 0.018 15.5 0.0 0.88 10.0 0.0 2.9 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain 53-BP1_Tudor PF09038.10 EFI28374.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor BRCT PF00533.26 EFI28374.1 - 0.26 11.7 0.5 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain FTHFS PF01268.19 EFI28376.1 - 1.2e-257 855.6 0.0 1.6e-257 855.1 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EFI28376.1 - 1.9e-67 225.6 0.3 4.8e-67 224.2 0.3 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EFI28376.1 - 1.5e-37 128.4 0.0 3.4e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EFI28376.1 - 0.07 12.1 0.2 0.14 11.1 0.2 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family SpoIIE PF07228.12 EFI28377.1 - 8e-10 38.9 0.0 1.3e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DNA_pol3_gamma3 PF12169.8 EFI28377.1 - 0.017 15.0 0.0 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III DUF1967 PF09269.11 EFI28377.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Peptidase_M49 PF03571.15 EFI28378.1 - 1.4e-208 693.8 0.0 2e-190 633.9 0.0 2.1 1 1 1 2 2 2 2 Peptidase family M49 TPR_2 PF07719.17 EFI28379.1 - 0.015 15.3 1.4 23 5.4 0.0 4.2 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 EFI28379.1 - 0.031 14.0 0.2 0.58 9.8 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_1 PF00515.28 EFI28379.1 - 0.047 13.5 0.5 5.8 6.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AKAP_110 PF05716.13 EFI28379.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) TPR_12 PF13424.6 EFI28379.1 - 0.17 12.2 12.8 3.2 8.1 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat CLASP_N PF12348.8 EFI28381.1 - 2.8e-33 115.4 1.2 2e-09 37.4 0.0 5.2 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 EFI28381.1 - 6.4e-12 44.7 8.7 0.0046 17.1 0.1 10.6 10 0 0 10 10 10 1 HEAT repeat Cnd1 PF12717.7 EFI28381.1 - 7.2e-10 39.1 0.2 0.9 9.6 0.0 6.8 6 2 2 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EFI28381.1 - 9.2e-09 35.6 15.8 0.0045 17.3 0.0 9.4 7 3 4 11 11 11 2 HEAT repeats TAN PF11640.8 EFI28381.1 - 1.3e-05 25.4 1.1 0.0066 16.6 0.0 4.3 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 EFI28381.1 - 0.00011 22.6 9.6 0.08 13.5 0.1 6.7 9 0 0 9 9 8 2 HEAT-like repeat Adaptin_N PF01602.20 EFI28381.1 - 0.0011 17.6 3.6 0.33 9.5 0.0 4.5 4 0 0 4 4 4 1 Adaptin N terminal region Nipped-B_C PF12830.7 EFI28381.1 - 0.0021 18.1 0.2 0.57 10.1 0.0 2.7 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus VHS PF00790.19 EFI28381.1 - 0.023 14.5 0.1 18 5.2 0.0 3.5 3 0 0 3 3 3 0 VHS domain MMS19_N PF14500.6 EFI28381.1 - 0.096 12.2 4.5 12 5.4 0.0 5.4 7 0 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II V-ATPase_H_C PF11698.8 EFI28381.1 - 1.2 9.2 2.6 10 6.2 0.0 3.8 4 1 1 5 5 5 0 V-ATPase subunit H ANAPC5 PF12862.7 EFI28382.1 - 4.4e-08 33.1 1.7 1.4e-07 31.5 0.1 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 Ribosomal_S21e PF01249.18 EFI28383.1 - 1.1e-37 128.0 0.0 2e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S21e 2OG-FeII_Oxy_2 PF13532.6 EFI28383.1 - 6.1e-34 117.9 0.0 1.6e-31 110.0 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily RabGAP-TBC PF00566.18 EFI28384.1 - 3.3e-41 141.3 6.3 5.5e-39 134.0 1.6 2.3 1 1 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 EFI28384.1 - 9.7e-08 31.7 0.0 6.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Rab-binding domain (RBD) RhoGEF PF00621.20 EFI28387.1 - 3.2e-15 56.8 0.2 7.1e-15 55.7 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain HSP70 PF00012.20 EFI28390.1 - 1.5e-262 872.1 3.9 1.7e-262 872.0 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EFI28390.1 - 9.4e-16 57.5 0.1 9.7e-15 54.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EFI28390.1 - 0.0015 18.3 0.0 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EFI28390.1 - 0.037 13.3 0.2 0.084 12.1 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EFI28390.1 - 0.096 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 StbA protein UCH_1 PF13423.6 EFI28391.1 - 1.9e-81 274.1 0.0 2.5e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EFI28391.1 - 5.5e-21 75.8 0.0 8.9e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.32 EFI28391.1 - 6.9e-05 23.5 0.9 1.4 10.0 0.0 4.6 4 1 1 5 5 5 2 WD domain, G-beta repeat DUF3535 PF12054.8 EFI28392.1 - 2.5e-102 343.4 0.1 2.9e-101 339.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EFI28392.1 - 1.9e-67 227.5 0.1 3.6e-67 226.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EFI28392.1 - 3.2e-17 62.9 0.0 9.9e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EFI28392.1 - 1.5e-06 28.0 19.4 1.6 9.2 0.1 9.2 11 0 0 11 11 8 3 HEAT repeat ResIII PF04851.15 EFI28392.1 - 4.3e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Vac14_Fab1_bd PF12755.7 EFI28392.1 - 7.5e-05 23.3 0.0 0.36 11.4 0.0 3.1 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 EFI28392.1 - 0.0028 16.8 0.1 0.013 14.6 0.0 2.1 3 0 0 3 3 3 1 Dopey, N-terminal CLASP_N PF12348.8 EFI28392.1 - 0.0028 17.3 0.0 0.083 12.4 0.0 2.9 2 0 0 2 2 2 1 CLASP N terminal DUF3385 PF11865.8 EFI28392.1 - 0.02 14.8 0.1 0.066 13.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 EFI28392.1 - 0.031 14.8 13.0 71 4.1 0.0 7.8 7 1 0 7 7 6 0 HEAT-like repeat ERCC3_RAD25_C PF16203.5 EFI28392.1 - 0.051 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Cupin_8 PF13621.6 EFI28393.1 - 2.8e-07 30.5 0.0 3e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain SOG2 PF10428.9 EFI28395.1 - 7.1e-54 183.9 2.5 7.1e-54 183.9 2.5 2.2 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.7 EFI28395.1 - 0.011 16.1 0.0 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EFI28395.1 - 0.15 11.8 0.1 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Leucine rich repeat FYVE PF01363.21 EFI28396.1 - 6.4e-16 58.3 2.8 6.4e-16 58.3 2.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger Rbsn PF11464.8 EFI28396.1 - 1e-14 54.0 2.9 1.9e-14 53.1 2.9 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.13 EFI28396.1 - 0.00063 19.7 6.6 0.00066 19.6 3.5 2.3 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type GATase_2 PF00310.21 EFI28399.1 - 1.8e-170 567.2 0.0 2.6e-170 566.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EFI28399.1 - 4.4e-155 516.4 0.0 7.8e-155 515.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EFI28399.1 - 1.2e-111 372.7 0.0 2.6e-110 368.3 0.0 2.1 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EFI28399.1 - 2.4e-87 291.5 3.7 4e-87 290.7 3.7 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EFI28399.1 - 1e-24 87.3 0.0 5.6e-24 84.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EFI28399.1 - 6.5e-22 77.4 0.1 1.4e-21 76.4 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DAO PF01266.24 EFI28399.1 - 1.6e-09 37.9 0.1 0.0022 17.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EFI28399.1 - 6.8e-08 32.6 0.0 2.5e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EFI28399.1 - 9.2e-08 31.7 0.5 0.0084 15.4 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EFI28399.1 - 1.2e-07 32.2 0.1 5.5e-05 23.6 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EFI28399.1 - 1.6e-05 23.8 1.0 4.8e-05 22.2 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EFI28399.1 - 0.00065 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FMN_dh PF01070.18 EFI28399.1 - 0.0025 16.9 0.9 0.011 14.7 1.1 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NAD_binding_7 PF13241.6 EFI28399.1 - 0.0042 17.5 0.1 2.7 8.5 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EFI28399.1 - 0.0054 15.9 0.0 0.0054 15.9 0.0 2.7 4 0 0 4 4 4 1 FAD binding domain AdoHcyase_NAD PF00670.21 EFI28399.1 - 0.0059 16.7 0.3 2.4 8.2 0.0 2.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_oxidored PF12831.7 EFI28399.1 - 0.011 15.1 1.3 0.026 13.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EFI28399.1 - 0.013 14.7 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EFI28399.1 - 0.019 14.3 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EFI28399.1 - 0.041 13.1 0.4 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EFI28399.1 - 0.076 12.1 1.5 0.67 9.0 0.1 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EFI28399.1 - 0.082 12.3 0.0 0.63 9.4 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EFI28399.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GATase_6 PF13522.6 EFI28399.1 - 0.18 12.0 0.1 0.67 10.2 0.1 2.0 2 0 0 2 2 1 0 Glutamine amidotransferase domain Peptidase_M13_N PF05649.13 EFI28400.1 - 1.9e-111 373.4 0.0 2.6e-111 373.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EFI28400.1 - 2.8e-65 219.8 0.4 4.5e-65 219.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M13 Mucin PF01456.17 EFI28400.1 - 0.0046 17.0 5.1 0.0079 16.2 5.1 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein 2OG-FeII_Oxy_2 PF13532.6 EFI28401.1 - 6.8e-10 39.5 0.0 7.2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ORC5_C PF14630.6 EFI28402.1 - 9.7e-43 146.7 0.0 1.4e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AMP-binding PF00501.28 EFI28403.1 - 2.6e-89 299.7 0.0 3.5e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EFI28403.1 - 4e-05 24.5 0.5 0.00015 22.7 0.7 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RSRP PF17069.5 EFI28404.1 - 0.12 11.9 0.6 0.17 11.5 0.6 1.3 1 1 0 1 1 1 0 Arginine/Serine-Rich protein 1 ArgoL1 PF08699.10 EFI28408.1 - 2.1e-07 30.5 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain Piwi PF02171.17 EFI28409.1 - 7.1e-55 186.4 0.0 9.2e-54 182.7 0.0 2.0 1 1 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 EFI28409.1 - 8.9e-08 32.3 0.0 1.9e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EFI28409.1 - 3.7e-06 27.2 0.0 0.00017 21.9 0.1 2.7 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 EFI28409.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Cyclin_N PF00134.23 EFI28411.1 - 9.1e-08 31.9 0.0 3e-07 30.2 0.0 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EFI28411.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Cyclin C-terminal domain SRP-alpha_N PF04086.13 EFI28412.1 - 2.2e-49 169.0 10.6 4.7e-48 164.6 10.6 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EFI28412.1 - 5e-45 153.6 0.2 4.1e-44 150.6 0.2 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EFI28412.1 - 6.5e-11 42.3 0.0 2.1e-10 40.7 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EFI28412.1 - 2.8e-05 23.2 0.2 0.00012 21.1 0.2 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EFI28412.1 - 0.0025 17.6 0.1 0.056 13.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain CbiA PF01656.23 EFI28412.1 - 0.014 15.5 0.1 0.034 14.2 0.1 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EFI28412.1 - 0.025 14.3 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EFI28412.1 - 0.041 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EFI28412.1 - 0.043 13.0 0.3 1.9 7.6 0.0 2.5 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_31 PF13614.6 EFI28412.1 - 0.062 13.2 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EFI28412.1 - 0.084 12.8 0.2 0.38 10.7 0.2 2.0 1 1 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 EFI28412.1 - 0.2 11.8 0.5 1.7 8.7 0.5 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase EndIII_4Fe-2S PF10576.9 EFI28413.1 - 0.075 13.4 0.3 0.16 12.3 0.3 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HOOK PF05622.12 EFI28414.1 - 5e-60 203.5 69.7 6.1e-58 196.6 43.5 2.6 1 1 1 2 2 2 2 HOOK protein Sec20 PF03908.13 EFI28414.1 - 0.39 10.6 13.7 0.17 11.8 3.3 3.7 3 1 0 3 3 3 0 Sec20 DUF1318 PF07027.12 EFI28414.1 - 0.41 11.1 0.1 0.41 11.1 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1318) EI24 PF07264.11 EFI28415.1 - 6.9e-14 52.5 1.1 1.2e-13 51.7 1.1 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AP2 PF00847.20 EFI28415.1 - 0.041 14.1 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 AP2 domain DUF3188 PF11384.8 EFI28415.1 - 0.08 12.7 0.0 0.38 10.5 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DUF3341 PF11821.8 EFI28415.1 - 0.31 10.7 4.8 0.58 9.8 4.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) RNA12 PF10443.9 EFI28416.1 - 1.4e-113 380.0 0.0 5.1e-60 203.5 0.0 2.1 1 1 1 2 2 2 2 RNA12 protein AAA_16 PF13191.6 EFI28416.1 - 1e-06 29.3 0.0 3.4e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EFI28416.1 - 1.7e-05 24.8 0.0 0.00053 20.0 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EFI28416.1 - 0.00017 21.9 0.0 0.0006 20.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EFI28416.1 - 0.00029 20.1 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EFI28416.1 - 0.0014 18.8 0.0 0.0042 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EFI28416.1 - 0.0016 18.9 0.0 0.0037 17.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RRM_1 PF00076.22 EFI28416.1 - 0.0018 18.1 0.0 0.0053 16.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.6 EFI28416.1 - 0.0028 17.7 0.0 0.0073 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EFI28416.1 - 0.005 16.8 0.0 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EFI28416.1 - 0.011 16.3 0.0 0.039 14.5 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EFI28416.1 - 0.015 15.3 0.0 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EFI28416.1 - 0.019 14.1 0.0 0.053 12.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 EFI28416.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hydrolase PF00702.26 EFI28416.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NACHT PF05729.12 EFI28416.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 EFI28421.1 - 2e-41 141.5 0.0 4.2e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EFI28421.1 - 2.8e-06 27.0 0.1 7.4e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EFI28421.1 - 5.5e-05 23.5 0.0 0.003 17.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EFI28421.1 - 6.7e-05 22.9 0.0 0.00025 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EFI28421.1 - 0.00014 22.0 0.0 0.00046 20.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EFI28421.1 - 0.00021 21.7 0.1 0.0039 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EFI28421.1 - 0.00037 19.7 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EFI28421.1 - 0.0032 17.2 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EFI28421.1 - 0.012 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EFI28421.1 - 0.016 14.9 0.1 0.089 12.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EFI28421.1 - 0.018 15.2 0.1 0.054 13.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EFI28421.1 - 0.019 14.4 0.0 0.053 13.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EFI28421.1 - 0.028 14.3 0.8 5.8 6.8 0.0 2.9 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EFI28421.1 - 0.03 14.7 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EFI28421.1 - 0.033 14.7 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EFI28421.1 - 0.038 13.8 0.0 0.094 12.6 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EFI28421.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EFI28421.1 - 0.049 12.8 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EFI28421.1 - 0.081 12.7 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EFI28421.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EFI28421.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.9 EFI28422.1 - 3.3e-24 85.6 0.0 2.8e-13 50.0 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EFI28422.1 - 2.6e-10 40.8 0.0 8.1e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EFI28422.1 - 4.6e-05 23.3 0.0 7.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 EFI28423.1 - 1.7e-33 116.1 0.0 7.3e-27 94.4 0.7 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28423.1 - 1.5e-11 44.1 0.7 2.9e-11 43.2 0.7 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EFI28423.1 - 0.0073 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3987 PF13148.6 EFI28423.1 - 5.8 5.8 13.3 0.36 9.8 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pkinase_Tyr PF07714.17 EFI28424.1 - 6.3e-39 133.8 0.0 1.1e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EFI28424.1 - 1.6e-35 122.8 0.0 9.2e-35 120.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain L27_2 PF09045.10 EFI28424.1 - 0.014 15.4 0.3 0.027 14.4 0.3 1.5 1 0 0 1 1 1 0 L27_2 Kinase-like PF14531.6 EFI28424.1 - 0.047 13.0 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 EFI28424.1 - 0.1 12.2 0.4 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Mlf1IP PF10248.9 EFI28426.1 - 0.11 12.4 0.6 7.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Pkinase_Tyr PF07714.17 EFI28427.1 - 1.4e-42 145.8 0.0 6.4e-42 143.6 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 EFI28427.1 - 9.2e-41 139.9 0.0 1.9e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 EFI28427.1 - 9.2e-14 52.0 1.1 1e-07 32.4 0.1 3.1 2 1 1 3 3 3 2 RasGEF domain RasGEF_N PF00618.20 EFI28427.1 - 1.3e-07 31.7 0.0 6e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Kinase-like PF14531.6 EFI28427.1 - 0.00046 19.6 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EFI28427.1 - 0.054 12.3 0.0 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase MFS_1 PF07690.16 EFI28428.1 - 2.3e-38 132.1 32.2 2.3e-38 132.1 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EFI28428.1 - 1.3e-06 27.6 10.4 1.3e-06 27.6 10.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EFI28428.1 - 1.3e-06 27.1 1.1 1.3e-06 27.1 1.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) RRM_1 PF00076.22 EFI28429.1 - 2.1e-26 91.5 0.0 1.4e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 EFI28429.1 - 1.1e-21 75.2 0.0 3.3e-05 23.3 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 EFI28429.1 - 8.3e-06 25.6 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 EFI28429.1 - 0.064 12.7 0.0 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif Glyco_hydro_61 PF03443.14 EFI28431.1 - 7.1e-28 98.0 0.0 9.1e-28 97.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.6 EFI28431.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Wzt C-terminal domain NYN PF01936.18 EFI28432.1 - 2.3e-35 122.2 0.0 5.9e-19 69.0 0.0 2.6 2 0 0 2 2 2 2 NYN domain eRF1_2 PF03464.15 EFI28435.1 - 9.9e-45 152.1 0.0 1.8e-44 151.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EFI28435.1 - 3.7e-40 136.9 0.4 8.3e-40 135.8 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EFI28435.1 - 4.4e-19 68.8 0.0 7.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EFI28435.1 - 1.5e-10 41.5 0.0 2.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EFI28435.1 - 1.5e-08 35.0 0.0 2.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Cmc1 PF08583.10 EFI28436.1 - 0.01 15.8 2.3 0.014 15.4 2.3 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like FTR PF01913.18 EFI28437.1 - 0.21 11.5 0.0 0.23 11.4 0.0 1.0 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Linker_histone PF00538.19 EFI28439.1 - 4e-24 84.8 0.0 4e-24 84.8 0.0 2.6 2 0 0 2 2 2 1 linker histone H1 and H5 family EI24 PF07264.11 EFI28440.1 - 5.3e-39 134.3 13.5 7.3e-39 133.8 13.5 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4349 PF14257.6 EFI28440.1 - 0.1 12.0 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ADH_zinc_N_2 PF13602.6 EFI28441.1 - 7.1e-23 82.1 0.0 1.3e-22 81.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EFI28441.1 - 1.9e-15 57.0 0.0 5.5e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EFI28441.1 - 0.0015 18.4 0.0 0.12 12.2 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 EFI28441.1 - 0.07 12.8 0.6 0.19 11.4 0.4 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 EFI28441.1 - 0.11 12.7 0.1 0.29 11.4 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N_2 PF13602.6 EFI28442.1 - 1.4e-16 61.8 0.0 2.8e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EFI28442.1 - 3.1e-07 30.4 0.0 1.1e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EFI28442.1 - 0.094 12.6 0.0 0.36 10.7 0.0 1.8 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 EFI28442.1 - 0.1 12.3 1.3 0.15 11.7 0.4 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NADase_NGA PF07461.11 EFI28443.1 - 1.5 7.6 11.1 14 4.4 0.1 4.5 2 2 3 5 5 5 0 Nicotine adenine dinucleotide glycohydrolase (NADase) 2OG-FeII_Oxy_3 PF13640.6 EFI28444.1 - 4e-06 27.6 0.0 6.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ALG3 PF05208.13 EFI28445.1 - 7.6e-136 453.2 15.8 8.8e-136 453.0 15.8 1.0 1 0 0 1 1 1 1 ALG3 protein HSP70 PF00012.20 EFI28449.1 - 5.6e-239 794.3 5.6 6.9e-239 794.0 5.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EFI28449.1 - 2.7e-17 62.6 0.2 4e-16 58.7 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.20 EFI28449.1 - 0.0039 16.7 0.1 0.74 9.3 0.0 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 EFI28449.1 - 0.028 13.7 0.2 0.063 12.5 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 EFI28449.1 - 0.03 14.0 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1539 PF07560.11 EFI28449.1 - 0.036 14.2 0.1 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Granin PF01271.17 EFI28450.1 - 0.29 10.0 2.5 0.35 9.7 2.5 1.0 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) CMD PF02627.20 EFI28454.1 - 2e-05 24.5 0.0 0.00092 19.2 0.0 2.5 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Ribonuclease_3 PF00636.26 EFI28455.1 - 1.4e-45 154.2 0.0 1.9e-23 83.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EFI28455.1 - 1.6e-29 102.6 0.0 1.5e-15 57.5 0.0 3.4 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 EFI28455.1 - 6.5e-19 68.3 0.0 3.3e-15 56.4 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 EFI28455.1 - 3.3e-16 59.2 0.1 6.9e-16 58.2 0.1 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.15 EFI28455.1 - 4e-15 56.2 0.0 6.9e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EFI28455.1 - 8.6e-15 54.9 0.0 1.7e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EFI28455.1 - 1.2e-05 25.1 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase COX17 PF05051.13 EFI28458.1 - 2.1e-20 72.8 6.1 3e-20 72.3 6.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) F-box PF00646.33 EFI28459.1 - 0.081 12.8 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain Lactamase_B PF00753.27 EFI28460.1 - 4.9e-21 75.7 0.3 6.8e-21 75.2 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 EFI28460.1 - 2.1e-13 50.0 0.0 3.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 EFI28460.1 - 0.00025 20.6 0.2 0.00054 19.5 0.1 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain HMG_box PF00505.19 EFI28461.1 - 1.1e-06 28.9 4.2 1.2e-05 25.6 4.2 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EFI28461.1 - 0.00065 20.2 0.8 0.0013 19.3 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.7 EFI28462.1 - 2.5e-07 30.4 0.0 9.3e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 F-box-like Hist_deacetyl PF00850.19 EFI28465.1 - 9.1e-80 268.4 0.0 1.2e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyoxalase_3 PF13468.6 EFI28467.1 - 1.1e-28 100.5 0.0 1.5e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Polysacc_lyase PF14099.6 EFI28468.1 - 0.0024 17.8 0.0 0.0078 16.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide lyase Methyltransf_12 PF08242.12 EFI28471.1 - 1.5e-09 38.4 0.0 1.1e-07 32.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EFI28471.1 - 4e-09 37.1 0.0 3.7e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EFI28471.1 - 5.2e-09 36.1 0.0 9.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EFI28471.1 - 3.1e-08 34.1 0.0 0.0001 22.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EFI28471.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EFI28471.1 - 0.0004 20.2 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EFI28471.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain PCMT PF01135.19 EFI28471.1 - 0.024 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EFI28471.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_33 PF10017.9 EFI28471.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent TehB PF03848.14 EFI28471.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.9 EFI28471.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DREV PF05219.12 EFI28471.1 - 0.22 10.6 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_7 PF03492.15 EFI28471.1 - 0.26 10.5 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase WD40 PF00400.32 EFI28472.1 - 3.8e-39 132.0 24.2 3.2e-09 37.3 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EFI28472.1 - 6.3e-23 80.9 0.8 2.7e-06 27.6 0.0 7.4 3 1 5 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EFI28472.1 - 3e-08 33.8 0.2 0.00035 20.5 0.0 3.2 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EFI28472.1 - 0.00047 19.2 0.6 0.14 11.1 0.0 3.4 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EFI28472.1 - 0.025 13.3 0.3 8.4 5.0 0.0 3.4 2 1 1 3 3 3 0 Nup133 N terminal like Frtz PF11768.8 EFI28472.1 - 0.072 11.4 0.0 0.35 9.1 0.0 1.8 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 EFI28472.1 - 0.18 9.8 0.0 0.27 9.2 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Det1 PF09737.9 EFI28472.1 - 0.26 10.3 0.0 0.44 9.6 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Pheromone PF08015.11 EFI28474.1 - 7e-06 27.0 1.3 0.00038 21.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI28475.1 - 7e-06 27.0 1.3 0.00038 21.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI28477.1 - 7e-06 27.0 1.3 0.00038 21.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.11 EFI28478.1 - 7e-06 27.0 1.3 0.00038 21.4 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone p450 PF00067.22 EFI28479.1 - 1.2e-45 156.1 0.4 9e-24 84.0 0.0 3.3 3 0 0 3 3 3 3 Cytochrome P450 BtrH_N PF14399.6 EFI28479.1 - 0.076 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal p450 PF00067.22 EFI28480.1 - 3.8e-10 39.1 0.1 4.5e-10 38.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIFR_N PF18207.1 EFI28480.1 - 0.21 12.0 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain p450 PF00067.22 EFI28481.1 - 1.7e-57 195.2 0.0 1.9e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF929 PF06053.11 EFI28483.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Tet_JBP PF12851.7 EFI28483.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.7 EFI28489.1 - 1.7e-06 27.6 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily KDZ PF18758.1 EFI28491.1 - 1.8e-42 145.5 0.1 3e-42 144.7 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 EFI28491.1 - 1.1e-19 70.6 0.0 1.9e-17 63.4 0.0 2.7 2 0 0 2 2 2 2 CxC2 like cysteine cluster associated with KDZ transposases Phage_integrase PF00589.22 EFI28492.1 - 0.047 13.5 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Phage integrase family DUF5401 PF17380.2 EFI28493.1 - 0.055 11.5 6.3 0.067 11.3 6.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SRP-alpha_N PF04086.13 EFI28496.1 - 0.0068 16.4 9.6 0.012 15.6 9.6 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 EFI28497.1 - 0.083 11.2 26.6 0.11 10.7 26.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4778 PF16008.5 EFI28497.1 - 0.3 11.1 14.3 0.43 10.6 14.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) LPD28 PF18843.1 EFI28498.1 - 0.0006 19.4 0.1 0.019 14.6 0.0 2.5 1 1 1 2 2 2 2 Large polyvalent protein associated domain 28 VirK PF06903.12 EFI28498.1 - 0.036 14.1 0.0 15 5.8 0.0 2.8 2 1 1 3 3 3 0 VirK protein FTP PF07504.13 EFI28498.1 - 0.11 12.3 0.4 0.77 9.6 0.1 2.4 2 1 1 3 3 3 0 Fungalysin/Thermolysin Propeptide Motif LRR_6 PF13516.6 EFI28499.1 - 1.5e-08 34.0 7.2 0.25 11.5 0.2 6.6 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 EFI28499.1 - 0.00038 20.8 3.6 2.8 8.5 0.1 5.1 5 2 2 7 7 7 2 Leucine Rich repeats (2 copies) RPN2_C PF18004.1 EFI28499.1 - 1.8 8.4 9.7 11 5.9 6.8 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Chromate_transp PF02417.15 EFI28502.1 - 1.3e-62 210.6 33.6 1.8e-36 125.7 14.1 2.2 2 0 0 2 2 2 2 Chromate transporter TMP_2 PF06791.13 EFI28502.1 - 0.56 9.9 2.3 0.82 9.3 0.8 1.8 2 0 0 2 2 2 0 Prophage tail length tape measure protein CcmH PF03918.14 EFI28502.1 - 2.2 7.6 4.1 2.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Transposase_21 PF02992.14 EFI28504.1 - 0.00039 19.7 0.0 0.00084 18.6 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 EFI28504.1 - 0.0067 16.0 0.1 0.0067 16.0 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) SK_channel PF03530.14 EFI28508.1 - 0.023 14.7 0.1 0.038 14.0 0.0 1.4 1 1 0 1 1 1 0 Calcium-activated SK potassium channel GWT1 PF06423.12 EFI28508.1 - 0.17 12.0 0.3 0.22 11.6 0.3 1.1 1 0 0 1 1 1 0 GWT1 zf-MYND PF01753.18 EFI28513.1 - 3.7e-09 36.5 7.0 9e-09 35.3 7.0 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 EFI28513.1 - 0.15 13.2 5.4 0.42 11.8 5.4 1.7 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF5639 PF18690.1 EFI28515.1 - 0.23 11.6 1.3 1.8 8.8 0.0 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5639) Babuvirus_MP PF07234.11 EFI28517.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Movement and RNA silencing protein Skp1_POZ PF03931.15 EFI28518.1 - 4.1e-05 23.7 0.0 6.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 EFI28518.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Skp1 family, dimerisation domain PKS_DE PF18369.1 EFI28518.1 - 0.018 15.6 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain G_path_suppress PF15991.5 EFI28522.1 - 0.44 10.6 5.3 0.55 10.3 5.3 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor Pox_T4_N PF04491.12 EFI28524.1 - 0.21 11.5 0.2 3.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus DUF2730 PF10805.8 EFI28525.1 - 0.031 14.4 1.3 1.5 8.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Peptidase_C48 PF02902.19 EFI28528.1 - 0.00027 20.8 0.1 0.00056 19.8 0.1 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3524 PF12038.8 EFI28530.1 - 0.041 13.7 0.5 7.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) DUF3524 PF12038.8 EFI28531.1 - 0.041 13.7 0.5 7.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) DUF1996 PF09362.10 EFI28535.1 - 1.6e-66 224.7 0.0 2.3e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BTB PF00651.31 EFI28538.1 - 0.00013 22.1 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Cir_N PF10197.9 EFI28539.1 - 1.9e-05 24.8 0.1 1.9e-05 24.8 0.1 3.6 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR RE_AccI PF09545.10 EFI28541.1 - 0.03 13.3 0.0 0.037 13.0 0.0 1.0 1 0 0 1 1 1 0 AccI restriction endonuclease AbiEii PF08843.11 EFI28541.1 - 0.14 12.1 0.1 0.56 10.1 0.0 1.7 1 1 1 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Runt PF00853.19 EFI28541.1 - 0.14 11.7 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Runt domain zf-MYND PF01753.18 EFI28542.1 - 2.3e-08 34.0 7.2 4.3e-08 33.1 7.2 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EFI28542.1 - 0.29 11.3 3.8 0.68 10.1 3.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF21 PF01595.20 EFI28543.1 - 3.1e-31 108.4 0.1 5e-31 107.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EFI28543.1 - 0.0062 17.0 0.1 0.29 11.6 0.0 2.8 3 0 0 3 3 3 1 CBS domain Pkinase PF00069.25 EFI28544.1 - 2.7e-17 63.0 0.0 2.3e-13 50.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28544.1 - 8.2e-08 31.8 0.0 0.0092 15.3 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Epimerase PF01370.21 EFI28545.1 - 1.4e-21 77.1 0.0 2.2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EFI28545.1 - 2.3e-16 59.6 0.0 3.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EFI28545.1 - 8.7e-11 41.8 0.1 1.1e-09 38.1 0.1 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EFI28545.1 - 3e-09 37.0 0.0 4.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EFI28545.1 - 2.8e-08 33.3 0.0 2.3e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EFI28545.1 - 1.9e-06 27.7 0.0 3.2e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EFI28545.1 - 0.00031 20.3 0.0 0.0016 18.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase zf-LITAF-like PF10601.9 EFI28546.1 - 1.9e-21 76.1 5.9 2.6e-21 75.6 5.9 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EFI28546.1 - 0.011 15.9 0.4 0.3 11.3 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-ISL3 PF14690.6 EFI28546.1 - 0.042 14.5 2.0 2.6 8.8 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.7 EFI28546.1 - 0.13 12.3 6.1 6.7 6.8 1.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EFI28546.1 - 0.13 12.0 1.6 10 6.0 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 EFI28546.1 - 0.73 9.9 3.4 11 6.1 3.4 2.1 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NOB1_Zn_bind PF08772.11 EFI28546.1 - 1.8 8.8 6.2 7.6 6.8 0.1 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Asparaginase_2 PF01112.18 EFI28547.1 - 3.5e-74 249.6 0.0 2.3e-52 178.0 0.0 2.2 2 0 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.21 EFI28547.1 - 0.034 12.9 0.3 0.12 11.1 0.5 1.7 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase TPR_10 PF13374.6 EFI28548.1 - 1.8e-56 186.6 28.8 0.00018 21.3 0.2 15.3 14 1 0 14 14 14 12 Tetratricopeptide repeat CHAT PF12770.7 EFI28548.1 - 3.3e-25 89.1 0.0 9.2e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EFI28548.1 - 2.5e-23 82.1 20.7 0.12 12.7 0.1 14.7 9 5 6 15 15 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 EFI28548.1 - 2.5e-09 36.9 0.5 6.6 7.4 0.0 10.7 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_11 PF13414.6 EFI28548.1 - 5.5e-09 35.6 0.1 1.9 8.3 0.0 8.3 8 0 0 8 8 8 1 TPR repeat TPR_8 PF13181.6 EFI28548.1 - 1.5e-08 34.1 1.5 15 6.1 0.0 9.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 EFI28548.1 - 7.6e-08 31.9 22.1 1.1 9.2 0.0 12.4 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_2 PF07719.17 EFI28548.1 - 2.1e-06 27.4 25.8 1.2 9.4 0.0 11.9 13 0 0 13 13 12 2 Tetratricopeptide repeat DUF2730 PF10805.8 EFI28548.1 - 8.6e-06 25.8 0.1 23 5.2 0.0 7.0 8 2 1 9 9 8 0 Protein of unknown function (DUF2730) TPR_14 PF13428.6 EFI28548.1 - 0.0029 18.3 20.6 63 4.8 0.2 11.9 11 2 3 14 14 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 EFI28548.1 - 0.0045 16.9 12.8 86 3.5 0.3 11.1 13 0 0 13 13 13 0 Tetratricopeptide repeat Coleoptericin PF06286.11 EFI28548.1 - 0.012 15.7 0.0 9.7 6.3 0.0 4.1 3 1 1 5 5 5 0 Coleoptericin Sec8_exocyst PF04048.14 EFI28548.1 - 0.027 14.3 0.0 0.39 10.6 0.0 2.9 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain Vta1_C PF18097.1 EFI28548.1 - 0.076 12.7 4.1 37 4.1 0.0 4.6 3 0 0 3 3 3 0 Vta1 C-terminal domain DUF4404 PF14357.6 EFI28548.1 - 0.95 10.1 10.3 17 6.1 0.4 5.9 5 2 1 6 6 6 0 Domain of unknown function (DUF4404) TPR_16 PF13432.6 EFI28548.1 - 1.4 9.6 9.5 6.1 7.6 1.8 5.1 5 1 0 6 6 5 0 Tetratricopeptide repeat RNase_H PF00075.24 EFI28550.1 - 0.13 12.4 0.5 0.19 11.9 0.5 1.5 1 1 0 1 1 1 0 RNase H zf-MYND PF01753.18 EFI28551.1 - 0.13 12.4 6.1 0.38 10.9 6.1 1.8 1 0 0 1 1 1 0 MYND finger DUF4404 PF14357.6 EFI28552.1 - 0.036 14.7 0.0 0.11 13.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Ifi-6-16 PF06140.13 EFI28552.1 - 0.038 13.9 11.7 0.052 13.5 11.1 1.5 1 1 0 1 1 1 0 Interferon-induced 6-16 family ACP_syn_III PF08545.10 EFI28553.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EHD_N PF16880.5 EFI28553.1 - 0.34 10.9 1.5 3.6 7.6 0.2 2.5 2 0 0 2 2 2 0 N-terminal EH-domain containing protein adh_short PF00106.25 EFI28555.1 - 4.5e-09 36.0 0.3 1.1e-08 34.8 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EFI28555.1 - 0.00024 20.8 0.1 0.0028 17.2 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AIRC PF00731.20 EFI28555.1 - 2.8 7.5 5.6 2.3 7.8 3.3 1.9 1 1 1 2 2 2 0 AIR carboxylase DHC_N1 PF08385.12 EFI28556.1 - 1.3e-124 416.9 4.8 1.3e-124 416.9 4.8 2.8 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 ApoLp-III PF07464.11 EFI28556.1 - 0.0078 16.3 0.8 21 5.2 0.0 4.4 4 0 0 4 4 4 2 Apolipophorin-III precursor (apoLp-III) Glyco_transf_22 PF03901.17 EFI28562.1 - 0.0067 15.7 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ThrE PF06738.12 EFI28562.1 - 0.062 12.7 0.1 0.062 12.7 0.1 2.0 2 1 1 3 3 3 0 Putative threonine/serine exporter MARVEL PF01284.23 EFI28562.1 - 0.19 11.8 3.6 0.23 11.5 0.7 2.1 2 0 0 2 2 2 0 Membrane-associating domain RNase_PH PF01138.21 EFI28564.1 - 8.6e-10 39.2 0.0 1.2e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Med9 PF07544.13 EFI28565.1 - 4.2e-08 33.2 0.5 6.3e-08 32.6 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HU-CCDC81_bac_2 PF18175.1 EFI28565.1 - 0.039 13.8 0.2 0.1 12.5 0.1 1.7 1 1 1 2 2 2 0 CCDC81-like prokaryotic HU domain 2 eIF3_N PF09440.10 EFI28565.1 - 0.086 13.3 0.5 0.12 12.8 0.5 1.2 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Prefoldin_3 PF13758.6 EFI28565.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit TPR_11 PF13414.6 EFI28566.1 - 0.0024 17.5 0.2 0.0048 16.6 0.2 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EFI28566.1 - 0.0071 16.4 1.9 0.63 10.3 1.8 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4470 PF14737.6 EFI28567.1 - 1e-13 51.3 0.0 2.2e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.17 EFI28567.1 - 3.3e-06 26.8 2.3 0.016 15.3 0.9 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EFI28567.1 - 0.027 14.7 0.5 20 5.7 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EFI28567.1 - 0.7 9.8 7.1 1.8 8.5 0.5 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat GSP_synth PF03738.14 EFI28569.1 - 0.0091 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp AAA PF00004.29 EFI28570.1 - 9.1e-41 139.4 0.0 1.5e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EFI28570.1 - 2.1e-29 101.3 0.2 6.4e-29 99.7 0.2 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EFI28570.1 - 1.2e-23 83.0 6.8 2.8e-23 81.8 6.8 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EFI28570.1 - 6.2e-09 35.5 0.1 5e-08 32.6 0.0 2.5 3 0 0 3 3 3 1 AAA+ lid domain AAA_22 PF13401.6 EFI28570.1 - 3e-06 27.5 0.2 0.022 15.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 EFI28570.1 - 3.9e-06 27.3 0.6 0.0015 18.9 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EFI28570.1 - 6.5e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EFI28570.1 - 1.2e-05 25.2 0.0 3.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EFI28570.1 - 9e-05 22.5 0.0 0.00028 20.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EFI28570.1 - 0.00021 21.3 0.1 0.0005 20.1 0.0 1.6 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 EFI28570.1 - 0.00066 18.9 0.0 0.0018 17.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EFI28570.1 - 0.00077 19.2 0.0 0.0028 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EFI28570.1 - 0.0011 18.2 0.1 0.0024 17.1 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EFI28570.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EFI28570.1 - 0.002 18.6 0.0 0.0049 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EFI28570.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 EFI28570.1 - 0.0068 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EFI28570.1 - 0.0072 15.9 0.2 0.69 9.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 EFI28570.1 - 0.014 14.8 0.1 3.3 7.0 0.0 2.3 1 1 1 2 2 2 0 KaiC KAP_NTPase PF07693.14 EFI28570.1 - 0.028 13.7 0.1 1.1 8.4 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Terminase_6C PF17289.2 EFI28570.1 - 0.029 14.5 0.4 0.076 13.1 0.4 1.7 1 0 0 1 1 1 0 Terminase RNaseH-like domain AAA_17 PF13207.6 EFI28570.1 - 0.032 14.7 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EFI28570.1 - 0.036 14.0 0.0 0.28 11.1 0.0 2.3 1 1 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 EFI28570.1 - 0.041 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EFI28570.1 - 0.044 13.7 0.1 1.3 8.9 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 EFI28570.1 - 0.049 13.0 0.6 8.7 5.7 0.0 2.7 2 1 1 3 3 3 0 Bacterial TniB protein PhoH PF02562.16 EFI28570.1 - 0.054 12.9 0.8 0.16 11.4 0.1 2.1 2 1 1 3 3 2 0 PhoH-like protein AAA_7 PF12775.7 EFI28570.1 - 0.058 12.9 0.0 0.2 11.1 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 EFI28570.1 - 0.069 13.3 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 EFI28570.1 - 0.071 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EFI28570.1 - 0.11 11.7 0.1 1.7 7.8 0.1 2.2 1 1 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 EFI28570.1 - 0.13 12.0 0.0 0.62 9.8 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain AP3D1 PF06375.11 EFI28572.1 - 0.094 12.9 7.3 0.1 12.8 7.3 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Gram_pos_anchor PF00746.21 EFI28572.1 - 2.2 8.3 0.0 2.2 8.3 0.0 3.5 3 1 0 3 3 3 0 LPXTG cell wall anchor motif BLM10_mid PF16507.5 EFI28574.1 - 3.3e-184 613.4 0.0 9.2e-184 611.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EFI28574.1 - 9.6e-31 105.6 0.0 9.6e-31 105.6 0.0 4.8 6 0 0 6 6 6 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 EFI28574.1 - 0.0039 17.6 0.0 0.061 13.7 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EFI28574.1 - 0.0075 16.4 1.0 0.22 11.9 0.2 3.7 3 0 0 3 3 3 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EFI28574.1 - 0.0083 16.7 0.0 0.044 14.4 0.0 2.3 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 EFI28574.1 - 0.015 15.6 3.4 0.075 13.4 0.1 3.6 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain BLM10_N PF16547.5 EFI28574.1 - 0.055 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal U3snoRNP10 PF12397.8 EFI28574.1 - 0.1 12.9 0.3 1.6 9.1 0.1 3.0 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Translin PF01997.16 EFI28575.1 - 2.6e-34 119.0 0.1 7.8e-26 91.3 0.0 2.1 1 1 1 2 2 2 2 Translin family BLM10_mid PF16507.5 EFI28576.1 - 3.8e-194 646.2 0.0 9.3e-194 644.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EFI28576.1 - 2.7e-31 107.3 0.5 2.2e-30 104.4 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 EFI28576.1 - 8.4e-09 34.9 6.9 0.028 14.6 0.1 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 EFI28576.1 - 0.00063 20.1 0.5 0.18 12.2 0.1 4.5 4 0 0 4 4 4 1 HEAT repeats XPA_C PF05181.12 EFI28577.1 - 9.8e-24 83.1 1.8 2.1e-23 82.0 1.8 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EFI28577.1 - 0.016 15.2 3.8 0.016 15.2 3.8 2.9 3 0 0 3 3 3 0 XPA protein N-terminal OrfB_Zn_ribbon PF07282.11 EFI28577.1 - 0.62 10.0 9.3 0.78 9.7 3.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.9 EFI28577.1 - 0.7 10.0 7.4 6.1 7.0 0.3 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Ion_trans_N PF08412.10 EFI28577.1 - 2.9 7.6 4.6 11 5.8 0.1 2.7 2 0 0 2 2 2 0 Ion transport protein N-terminal PTH2 PF01981.16 EFI28579.1 - 3.4e-29 101.5 0.4 2.7e-28 98.6 0.4 1.9 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2760 PF10816.8 EFI28579.1 - 0.053 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) DUF2000 PF09391.10 EFI28579.1 - 0.1 12.5 0.4 1.2 9.0 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2000) Bromodomain PF00439.25 EFI28580.1 - 2.9e-42 142.6 0.2 8.1e-22 77.1 0.1 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EFI28580.1 - 5.7e-19 68.1 0.6 1.2e-18 67.0 0.6 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation CENP-Q PF13094.6 EFI28580.1 - 0.051 13.8 3.7 0.13 12.4 3.7 1.8 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit LegC3_N PF18654.1 EFI28580.1 - 0.67 9.1 4.7 1.2 8.3 4.7 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain FlxA PF14282.6 EFI28580.1 - 0.75 9.8 4.3 3.7 7.6 4.3 2.2 1 0 0 1 1 1 0 FlxA-like protein WD40 PF00400.32 EFI28581.1 - 1.6e-16 60.4 9.1 0.00033 21.4 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EFI28581.1 - 2.2e-05 24.7 0.0 1.8 8.9 0.0 5.0 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EFI28581.1 - 0.025 13.5 0.1 0.087 11.8 0.0 1.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pox_Ag35 PF03286.14 EFI28581.1 - 0.082 12.7 5.9 0.15 11.8 5.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DTHCT PF08070.11 EFI28581.1 - 0.55 11.0 15.8 0.46 11.2 11.4 2.6 2 0 0 2 2 2 0 DTHCT (NUC029) region Presenilin PF01080.17 EFI28581.1 - 3.8 6.2 5.8 5.5 5.6 5.8 1.1 1 0 0 1 1 1 0 Presenilin MRI PF15325.6 EFI28581.1 - 9.9 7.3 13.7 27 5.9 13.7 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection Ctr PF04145.15 EFI28582.1 - 1.2e-32 113.6 0.0 1.5e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family RWD PF05773.22 EFI28584.1 - 6.7e-14 52.2 0.5 3.2e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 RWD domain IBR PF01485.21 EFI28584.1 - 9.3e-13 48.2 24.1 1.8e-10 40.9 4.5 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain DUF4360 PF14273.6 EFI28588.1 - 6.3e-23 81.5 0.0 7.7e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MutS_V PF00488.21 EFI28589.1 - 2.7e-57 193.8 0.0 1e-56 192.0 0.0 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EFI28589.1 - 1.8e-30 106.6 2.7 1.8e-30 106.6 2.7 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EFI28589.1 - 6.8e-09 36.0 0.5 1.8e-08 34.6 0.1 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EFI28589.1 - 0.029 14.6 0.1 0.28 11.5 0.1 2.6 1 1 0 1 1 1 0 MutS domain II AAA_23 PF13476.6 EFI28589.1 - 0.063 13.8 1.4 1.7 9.1 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_27 PF13514.6 EFI28589.1 - 0.075 12.6 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EFI28591.1 - 1.4e-60 204.9 0.0 6.7e-60 202.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28591.1 - 1e-28 100.4 0.0 1.8e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EFI28591.1 - 0.0002 20.7 0.1 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EFI28591.1 - 0.0022 17.4 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EFI28591.1 - 0.0028 17.6 0.1 0.035 14.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EFI28591.1 - 0.013 14.4 0.0 0.033 13.1 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain TFIIS_C PF01096.18 EFI28592.1 - 1.7e-18 66.2 10.3 4.1e-18 64.9 1.3 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EFI28592.1 - 1.3e-08 34.6 4.9 5.1e-06 26.2 0.4 2.8 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit zf-RING_7 PF02591.15 EFI28592.1 - 1.2e-05 25.4 5.4 0.29 11.4 0.0 4.0 4 0 0 4 4 4 2 C4-type zinc ribbon domain DUF523 PF04463.12 EFI28592.1 - 9.5e-05 22.5 0.2 0.00011 22.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) DZR PF12773.7 EFI28592.1 - 0.00036 20.5 9.1 0.007 16.4 0.2 2.9 2 1 1 3 3 3 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 EFI28592.1 - 0.0012 18.8 10.3 0.0031 17.5 0.3 3.1 2 1 1 3 3 3 1 Transposase zinc-ribbon domain IBR PF01485.21 EFI28592.1 - 0.0016 18.6 8.3 0.017 15.4 0.2 2.5 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain PHD PF00628.29 EFI28592.1 - 0.0026 17.6 8.0 0.16 11.8 0.6 2.6 2 1 1 3 3 3 2 PHD-finger zinc_ribbon_10 PF10058.9 EFI28592.1 - 0.0074 16.0 5.1 9.3 6.1 0.0 4.0 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein CpXC PF14353.6 EFI28592.1 - 0.0083 16.2 8.3 0.46 10.5 0.7 3.4 2 1 0 3 3 3 1 CpXC protein DUF35_N PF12172.8 EFI28592.1 - 0.015 15.1 9.0 0.081 12.8 0.2 3.5 4 0 0 4 4 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PhnA_Zn_Ribbon PF08274.12 EFI28592.1 - 0.015 15.2 11.5 4.6 7.3 1.7 3.7 3 1 0 3 3 3 0 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.8 EFI28592.1 - 0.015 14.9 4.4 0.037 13.7 0.7 2.5 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DNA_ligase_ZBD PF03119.16 EFI28592.1 - 0.03 14.4 4.5 0.89 9.6 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 EFI28592.1 - 0.031 13.7 13.4 0.13 11.7 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EFI28592.1 - 0.031 14.4 10.3 5.5 7.2 0.0 3.8 3 1 1 4 4 4 0 Zinc ribbon domain Cytochrom_CIII PF02085.16 EFI28592.1 - 0.058 13.7 8.5 0.13 12.7 7.6 2.0 1 1 1 2 2 2 0 Class III cytochrome C family DUF3268 PF11672.8 EFI28592.1 - 0.079 13.3 0.8 0.079 13.3 0.8 2.2 2 1 1 3 3 3 0 zinc-finger-containing domain zinc_ribbon_4 PF13717.6 EFI28592.1 - 0.1 12.5 13.1 13 5.8 3.5 4.1 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 EFI28592.1 - 0.18 12.1 7.6 33 4.8 0.0 3.9 3 1 1 4 4 4 0 zinc-ribbon Mu-like_Com PF10122.9 EFI28592.1 - 0.28 10.6 4.9 5.5 6.5 0.1 2.6 3 0 0 3 3 2 0 Mu-like prophage protein Com Elf1 PF05129.13 EFI28592.1 - 0.3 11.2 8.1 3.5 7.7 1.3 2.8 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like TF_Zn_Ribbon PF08271.12 EFI28592.1 - 0.39 10.3 11.3 0.24 10.9 1.0 3.0 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C4_Topoisom PF01396.19 EFI28592.1 - 0.47 10.3 12.3 1.1 9.1 2.0 4.0 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF2387 PF09526.10 EFI28592.1 - 0.49 10.6 7.2 5.1 7.3 1.5 2.6 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Terminase_GpA PF05876.12 EFI28592.1 - 0.63 8.5 6.3 0.041 12.4 0.7 1.7 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) zf-LITAF-like PF10601.9 EFI28592.1 - 0.66 10.3 6.7 25 5.2 0.1 3.8 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain OrfB_Zn_ribbon PF07282.11 EFI28592.1 - 0.69 9.9 7.6 2.9 7.9 0.2 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-TFIIB PF13453.6 EFI28592.1 - 0.72 9.2 10.0 4.1 6.8 1.8 2.7 2 1 0 2 2 2 0 Transcription factor zinc-finger Cytochrome_C7 PF14522.6 EFI28592.1 - 0.95 9.5 9.8 38 4.4 9.8 2.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF1451 PF07295.11 EFI28592.1 - 1.2 9.2 10.4 0.21 11.6 0.9 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain Auto_anti-p27 PF06677.12 EFI28592.1 - 1.2 9.4 9.8 3.4 7.9 0.6 3.2 2 1 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_13 PF09855.9 EFI28592.1 - 1.3 9.3 0.1 1.3 9.3 0.1 3.3 2 2 2 4 4 4 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Nudix_N_2 PF14803.6 EFI28592.1 - 1.7 8.6 14.3 4.2 7.4 3.9 3.7 2 2 0 2 2 2 0 Nudix N-terminal A2L_zn_ribbon PF08792.10 EFI28592.1 - 1.8 8.4 12.8 2.4 8.0 0.1 4.2 5 0 0 5 5 5 0 A2L zinc ribbon domain Spt4 PF06093.13 EFI28592.1 - 2.1 8.5 5.4 3.7 7.7 0.2 2.6 2 2 0 2 2 2 0 Spt4/RpoE2 zinc finger DNA_RNApol_7kD PF03604.13 EFI28592.1 - 3 7.6 10.3 17 5.2 0.1 3.8 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-ACC PF17848.1 EFI28592.1 - 3.6 7.7 14.7 1.1 9.3 0.4 4.0 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_2 PF13240.6 EFI28592.1 - 3.7 7.4 19.8 4.1 7.2 0.4 3.7 3 1 0 3 3 3 0 zinc-ribbon domain zf-DNL PF05180.12 EFI28592.1 - 5.3 7.1 9.5 22 5.1 0.1 3.4 3 1 1 4 4 4 0 DNL zinc finger zf-IS66 PF13005.7 EFI28592.1 - 5.8 7.4 12.4 6.3 7.3 0.1 3.8 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 DUF4379 PF14311.6 EFI28592.1 - 6 7.3 11.6 4.7 7.7 1.2 3.7 3 1 1 4 4 4 0 Probable Zinc-ribbon domain YfcL PF08891.11 EFI28593.1 - 0.15 12.5 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 YfcL protein TIP120 PF08623.10 EFI28594.1 - 1e-54 184.8 0.3 1e-54 184.8 0.3 3.1 4 0 0 4 4 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EFI28594.1 - 1.1e-14 54.6 16.4 0.0034 17.7 0.9 9.5 8 2 2 10 10 9 4 HEAT repeats HEAT PF02985.22 EFI28594.1 - 4.1e-14 51.5 24.5 0.041 14.1 0.0 12.4 14 0 0 14 14 11 3 HEAT repeat HEAT_EZ PF13513.6 EFI28594.1 - 1.3e-09 38.4 28.4 0.083 13.4 0.1 12.3 12 2 2 14 14 14 3 HEAT-like repeat CLASP_N PF12348.8 EFI28594.1 - 1.2e-08 34.8 2.9 0.069 12.7 0.0 7.0 7 1 2 9 9 9 1 CLASP N terminal DUF3385 PF11865.8 EFI28594.1 - 4.9e-07 29.8 0.1 0.0035 17.3 0.0 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EFI28594.1 - 5.2e-06 27.0 1.3 7 7.3 0.0 7.0 7 0 0 7 7 7 1 Vacuolar 14 Fab1-binding region UME PF08064.13 EFI28594.1 - 5.3e-06 26.3 1.6 0.67 9.9 0.0 4.6 5 0 0 5 5 4 2 UME (NUC010) domain ParcG PF10274.9 EFI28594.1 - 9e-06 25.9 3.2 1.1 9.4 0.0 5.5 6 0 0 6 6 6 2 Parkin co-regulated protein Cnd1 PF12717.7 EFI28594.1 - 2.2e-05 24.6 9.5 0.23 11.5 0.2 6.5 5 2 1 7 7 6 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 EFI28594.1 - 2.8e-05 23.8 3.6 1.1 8.8 0.0 5.7 6 1 0 6 6 6 2 Tti2 family RTP1_C1 PF10363.9 EFI28594.1 - 9.6e-05 22.5 1.6 0.033 14.4 0.1 4.8 4 2 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 EFI28594.1 - 0.00033 19.9 33.6 0.076 12.1 0.3 6.8 5 1 1 6 6 6 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 EFI28594.1 - 0.00033 19.4 5.9 3.1 6.3 0.0 5.0 6 0 0 6 6 6 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 EFI28594.1 - 0.00048 20.2 0.3 0.26 11.4 0.1 4.4 4 0 0 4 4 3 1 V-ATPase subunit H Telomere_reg-2 PF10193.9 EFI28594.1 - 0.0054 17.2 4.1 2.8 8.4 0.0 4.2 4 0 0 4 4 3 1 Telomere length regulation protein DUF3384 PF11864.8 EFI28594.1 - 0.032 13.1 0.2 0.55 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3384) Dopey_N PF04118.14 EFI28594.1 - 0.05 12.7 6.5 5.9 5.9 0.0 4.8 5 0 0 5 5 5 0 Dopey, N-terminal API5 PF05918.11 EFI28594.1 - 0.056 12.2 1.1 1.2 7.8 0.2 3.0 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) FANCI_S2 PF14676.6 EFI28594.1 - 0.089 13.1 0.2 3 8.1 0.1 3.3 3 0 0 3 3 2 0 FANCI solenoid 2 Sec5 PF15469.6 EFI28594.1 - 0.12 12.2 0.5 0.31 10.8 0.5 1.7 1 0 0 1 1 1 0 Exocyst complex component Sec5 RRN3 PF05327.11 EFI28594.1 - 0.15 10.6 0.5 1.1 7.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 GP24_25 PF17388.2 EFI28594.1 - 2.7 8.0 5.0 5 7.1 2.3 2.8 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 NOA36 PF06524.12 EFI28594.1 - 9.9 5.4 10.1 16 4.7 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 EFI28595.1 - 7.6e-42 141.0 0.2 3e-20 71.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EFI28595.1 - 7e-15 55.9 3.0 5.1e-13 49.9 3.0 2.6 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.11 EFI28595.1 - 2e-05 24.6 0.2 0.0011 19.0 0.0 2.9 2 1 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 EFI28595.1 - 0.0015 18.3 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EFI28595.1 - 0.037 13.6 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EFI28595.1 - 0.074 13.1 0.1 8 6.6 0.1 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Ribonuc_L-PSP PF01042.21 EFI28596.1 - 4.5e-36 123.5 0.3 5.3e-36 123.3 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP TPR_10 PF13374.6 EFI28596.1 - 0.28 11.1 0.6 0.67 9.9 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat C2 PF00168.30 EFI28597.1 - 1.8e-18 66.7 0.9 1.6e-10 41.2 0.1 2.7 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 EFI28597.1 - 0.00028 20.4 0.0 0.13 11.7 0.1 2.4 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain Phage_holin_3_6 PF07332.11 EFI28597.1 - 0.0041 17.2 0.1 0.008 16.2 0.1 1.5 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III 2-Hacid_dh_C PF02826.19 EFI28600.1 - 2.4e-56 189.9 0.0 1.8e-54 183.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EFI28600.1 - 3.4e-09 36.5 0.0 6.9e-09 35.5 0.0 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EFI28600.1 - 0.00013 22.2 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EFI28600.1 - 0.085 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain RPN2_C PF18004.1 EFI28601.1 - 1.8e-42 145.0 0.6 2.2e-40 138.2 0.7 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EFI28601.1 - 6.1e-32 108.4 26.7 4.8e-09 36.2 0.0 9.2 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EFI28601.1 - 6.5e-18 64.9 4.8 1.1e-14 54.6 0.0 4.9 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 EFI28601.1 - 7.1e-05 22.7 0.6 7.2 7.2 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat DUF1702 PF08012.11 EFI28601.1 - 0.044 12.7 0.0 1.2 7.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1702) HEAT_EZ PF13513.6 EFI28601.1 - 0.081 13.4 8.3 0.89 10.1 0.0 5.0 5 1 2 7 7 7 0 HEAT-like repeat Cnd1 PF12717.7 EFI28601.1 - 0.15 12.1 0.1 15 5.6 0.0 3.4 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EFI28601.1 - 8.3 7.4 7.1 2.3e+02 3.0 0.0 5.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Crp PF00325.20 EFI28603.1 - 0.069 12.8 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DIE2_ALG10 PF04922.12 EFI28605.1 - 4.5e-112 375.2 5.2 6.2e-112 374.7 5.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Filament PF00038.21 EFI28606.1 - 0.004 16.8 12.6 0.0067 16.1 12.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein DNA_pol_B PF00136.21 EFI28606.1 - 0.61 8.7 3.3 0.93 8.1 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase family B DUF724 PF05266.14 EFI28606.1 - 6.6 6.5 9.2 13 5.5 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FMO-like PF00743.19 EFI28607.1 - 2.5e-33 115.3 0.0 1.3e-22 80.0 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EFI28607.1 - 2.7e-11 43.3 0.4 6e-08 32.3 0.0 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EFI28607.1 - 2.2e-05 23.8 0.0 0.0024 17.2 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EFI28607.1 - 9e-05 22.5 0.2 0.0037 17.3 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EFI28607.1 - 0.00062 19.0 0.4 0.072 12.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EFI28607.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UPF0542 PF15086.6 EFI28608.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Indigoidine_A PF04227.12 EFI28609.1 - 7e-122 406.3 0.0 1.3e-121 405.5 0.0 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EFI28609.1 - 1.4e-16 60.6 3.8 2e-10 40.5 0.6 3.0 2 1 1 3 3 3 2 pfkB family carbohydrate kinase Antimicrobial12 PF08107.11 EFI28609.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Pleurocidin family GATase_4 PF13230.6 EFI28610.1 - 6.8e-17 61.2 0.0 2.8e-16 59.2 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EFI28610.1 - 1.9e-08 34.6 0.0 3.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain PGM_PMM_I PF02878.16 EFI28611.1 - 1.4e-18 67.0 0.2 5.6e-08 32.6 0.1 2.9 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EFI28611.1 - 5.5e-11 42.5 0.2 1.7e-10 40.9 0.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EFI28611.1 - 0.00023 21.7 0.1 0.0021 18.6 0.1 2.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EFI28611.1 - 0.034 14.3 0.1 0.081 13.1 0.0 1.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ATP1G1_PLM_MAT8 PF02038.16 EFI28611.1 - 0.073 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family OppC_N PF12911.7 EFI28612.1 - 0.067 13.2 2.0 0.22 11.5 2.0 1.9 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PMP1_2 PF08114.11 EFI28612.1 - 0.071 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Herpes_gE PF02480.16 EFI28612.1 - 0.12 11.1 0.4 0.38 9.4 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1921 PF09081.10 EFI28613.1 - 0.016 15.4 1.7 0.028 14.7 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) DNA_pol_B PF00136.21 EFI28614.1 - 5e-102 342.0 0.0 6.6e-102 341.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EFI28614.1 - 6.8e-17 61.6 0.0 7.8e-09 35.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EFI28614.1 - 4.3e-13 49.5 3.3 4.3e-13 49.5 3.3 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta WD40 PF00400.32 EFI28615.1 - 1.1e-05 26.1 7.6 0.32 12.0 1.4 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat bZIP_1 PF00170.21 EFI28616.1 - 0.016 15.3 6.4 0.016 15.3 6.4 1.8 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EFI28616.1 - 0.053 13.6 1.1 0.053 13.6 1.1 3.2 3 1 1 4 4 4 0 Basic region leucine zipper ANAPC4 PF12896.7 EFI28617.1 - 6.1e-50 169.6 0.1 1e-49 168.8 0.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EFI28617.1 - 0.013 15.8 0.0 0.39 11.0 0.0 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EFI28617.1 - 0.014 15.3 0.2 2.7 8.1 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CHAD PF05235.14 EFI28617.1 - 0.1 12.5 0.7 0.22 11.5 0.7 1.5 1 0 0 1 1 1 0 CHAD domain UPF0160 PF03690.13 EFI28618.1 - 1.6e-118 396.0 0.0 2.8e-116 388.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF1467 PF07330.12 EFI28619.1 - 0.25 11.3 2.1 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) DUF1180 PF06679.12 EFI28619.1 - 0.7 10.3 4.4 1.1 9.7 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Ribosomal_S3_C PF00189.20 EFI28620.1 - 4.2e-24 84.9 0.2 1.6e-23 83.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EFI28620.1 - 6.9e-12 45.0 0.0 1.3e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EFI28620.1 - 0.06 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EFI28620.1 - 0.22 11.3 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus Thiolase_N PF00108.23 EFI28621.1 - 2.6e-64 217.1 0.0 4.3e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EFI28621.1 - 3.8e-39 133.1 2.0 5.1e-39 132.7 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EFI28621.1 - 0.024 14.2 0.1 0.15 11.7 0.1 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EFI28621.1 - 0.082 12.8 0.2 4.2 7.3 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Baculo_RING PF05883.11 EFI28621.1 - 0.17 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Memo PF01875.17 EFI28622.1 - 6.3e-77 258.4 0.0 7.2e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.18 EFI28623.1 - 1.3e-50 170.3 1.1 1.5e-50 170.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Methyltransf_23 PF13489.6 EFI28624.1 - 0.002 18.0 0.0 0.0065 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EFI28624.1 - 0.072 13.8 0.0 0.17 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain SMN PF06003.12 EFI28625.1 - 2.4e-07 30.3 8.5 6e-07 29.0 8.5 1.5 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 EFI28625.1 - 3.6e-06 27.0 0.0 1e-05 25.6 0.0 1.8 1 1 1 2 2 2 1 Tudor domain Relaxase PF03432.14 EFI28625.1 - 0.0014 18.3 3.1 0.0023 17.6 3.1 1.4 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain RRP36 PF06102.12 EFI28625.1 - 0.006 16.6 10.2 0.006 16.6 10.2 2.0 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 TSSC4 PF15264.6 EFI28625.1 - 0.0089 16.3 1.5 0.0089 16.3 1.5 1.8 2 0 0 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 RP-C_C PF11800.8 EFI28625.1 - 0.032 14.3 7.7 0.034 14.2 0.3 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Tudor_3 PF18115.1 EFI28625.1 - 0.041 13.7 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Pet20 PF08692.10 EFI28625.1 - 0.14 12.9 1.3 0.18 12.5 0.3 1.7 2 0 0 2 2 2 0 Mitochondrial protein Pet20 SLC12 PF03522.15 EFI28625.1 - 0.24 10.4 4.0 0.31 10.0 4.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EFI28625.1 - 0.46 9.2 3.4 0.61 8.8 3.4 1.2 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 EFI28625.1 - 1.4 9.1 8.4 2.8 8.1 2.8 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1764 PF08576.10 EFI28625.1 - 3.2 8.7 10.8 6.5 7.7 7.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Jak1_Phl PF17887.1 EFI28625.1 - 3.6 7.6 8.4 0.67 9.9 4.4 1.8 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain PDCD2_C PF04194.13 EFI28625.1 - 6.4 6.8 9.6 3.6 7.6 5.5 2.0 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain RNA_pol_Rpc4 PF05132.14 EFI28625.1 - 6.7 7.1 10.3 2 8.8 4.2 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 RIO1 PF01163.22 EFI28626.1 - 3.3e-49 167.0 0.0 6.3e-49 166.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EFI28626.1 - 4.6e-34 116.5 0.1 9.2e-34 115.5 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EFI28626.1 - 3.1e-10 40.4 0.0 0.00075 19.5 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EFI28626.1 - 1.8e-06 27.4 0.0 0.022 14.1 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Hamartin PF04388.12 EFI28626.1 - 0.09 11.4 10.9 0.11 11.1 10.9 1.1 1 0 0 1 1 1 0 Hamartin protein NOA36 PF06524.12 EFI28626.1 - 0.37 10.1 11.2 0.75 9.1 11.2 1.4 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 EFI28626.1 - 0.74 8.0 18.4 1.1 7.5 18.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 EFI28626.1 - 2.7 7.5 13.4 4.1 6.9 13.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 EFI28626.1 - 4.1 5.5 21.1 5.6 5.0 21.1 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EFI28626.1 - 6.5 6.0 25.1 9.7 5.4 25.1 1.2 1 0 0 1 1 1 0 BUD22 LAP1C PF05609.12 EFI28626.1 - 7.1 5.6 17.7 9.5 5.2 17.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2151 PF10221.9 EFI28626.1 - 7.6 5.0 9.4 11 4.4 9.4 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Pex14_N PF04695.13 EFI28627.1 - 7.7e-18 65.6 4.6 7.7e-18 65.6 4.6 7.8 5 4 0 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GRIP PF01465.20 EFI28627.1 - 1.5e-16 60.0 3.1 1.6e-16 59.9 0.5 2.4 2 0 0 2 2 2 1 GRIP domain Laminin_II PF06009.12 EFI28627.1 - 0.0021 18.1 1.5 0.0021 18.1 1.5 6.7 4 2 4 8 8 8 2 Laminin Domain II DUF4407 PF14362.6 EFI28627.1 - 0.0025 17.2 1.3 0.0025 17.2 1.3 6.2 2 1 5 7 7 7 3 Domain of unknown function (DUF4407) IFT57 PF10498.9 EFI28627.1 - 0.0092 15.0 1.1 0.0092 15.0 1.1 5.8 3 1 4 7 7 7 2 Intra-flagellar transport protein 57 DUF1664 PF07889.12 EFI28627.1 - 0.014 15.4 3.6 0.014 15.4 3.6 6.7 3 2 4 7 7 7 0 Protein of unknown function (DUF1664) DUF3138 PF11336.8 EFI28627.1 - 2.4 6.7 12.1 4.7 5.7 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) PepSY_TM PF03929.16 EFI28627.1 - 3.7 7.1 4.7 1.4 8.6 0.3 2.5 2 0 0 2 2 2 0 PepSY-associated TM region ARTD15_N PF18084.1 EFI28627.1 - 4.3 7.7 5.4 1.1e+02 3.1 0.2 4.3 4 0 0 4 4 4 0 ARTD15 N-terminal domain JAB PF01398.21 EFI28629.1 - 4.6e-12 46.0 0.0 8.2e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 EFI28629.1 - 0.0026 17.9 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) E1_4HB PF16191.5 EFI28629.1 - 0.13 12.5 0.0 1 9.6 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle DPBB_1 PF03330.18 EFI28630.1 - 2.4e-08 34.2 0.1 5.5e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase Retinal PF15449.6 EFI28630.1 - 0.74 7.5 13.7 0.71 7.6 13.7 1.0 1 0 0 1 1 1 0 Retinal protein SGL PF08450.12 EFI28631.1 - 1.4e-70 237.7 0.0 1.8e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EFI28631.1 - 0.00045 20.4 0.0 0.0025 18.0 0.0 2.0 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 EFI28631.1 - 0.0029 17.7 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Strictosidine synthase Lactonase PF10282.9 EFI28631.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EFI28631.1 - 0.2 11.6 0.3 0.2 11.6 0.3 1.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat zf-CCCH PF00642.24 EFI28632.1 - 7.8e-18 63.9 23.7 2.3e-05 24.1 0.6 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EFI28632.1 - 7.6e-13 48.1 30.0 9.5e-07 28.7 2.1 4.9 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EFI28632.1 - 4.7e-09 36.9 19.6 0.00057 20.6 0.3 4.8 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 EFI28632.1 - 2.3e-05 24.1 0.4 2.3e-05 24.1 0.4 4.8 6 0 0 6 6 6 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EFI28632.1 - 0.0025 18.2 0.5 0.0025 18.2 0.5 5.3 6 0 0 6 6 6 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EFI28632.1 - 0.87 9.8 15.8 2.4 8.4 0.4 3.9 1 1 3 4 4 4 0 Zinc-finger containing family zf-CCHC PF00098.23 EFI28632.1 - 3.3 8.0 8.0 0.31 11.2 2.7 2.2 2 0 0 2 2 2 0 Zinc knuckle PDT PF00800.18 EFI28633.1 - 9.8e-52 175.4 0.0 9.9e-50 168.9 0.0 2.1 1 1 0 1 1 1 1 Prephenate dehydratase eIF2A PF08662.11 EFI28634.1 - 1e-41 143.0 0.1 2.3e-37 128.7 0.0 4.1 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EFI28634.1 - 5.1e-07 29.4 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EFI28634.1 - 0.0033 18.2 2.1 0.87 10.6 0.1 5.0 5 1 0 5 5 5 1 WD domain, G-beta repeat Cucumo_2B PF03263.13 EFI28634.1 - 0.012 16.1 0.0 0.049 14.1 0.0 2.1 1 0 0 1 1 1 0 Cucumovirus protein 2B DUF4998 PF16389.5 EFI28634.1 - 0.021 14.4 0.1 0.077 12.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function Hap4_Hap_bind PF10297.9 EFI28635.1 - 4.6e-07 29.7 4.8 4.6e-07 29.7 4.8 2.1 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EFI28635.1 - 0.00019 21.5 13.2 0.00019 21.5 13.2 1.9 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 EFI28635.1 - 0.014 15.5 16.1 0.24 11.5 3.7 2.7 2 1 0 2 2 2 0 Basic region leucine zipper YabA PF06156.13 EFI28635.1 - 0.14 12.8 4.3 0.29 11.8 4.3 1.5 1 0 0 1 1 1 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 EFI28635.1 - 0.25 10.9 7.1 0.39 10.3 7.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Uso1_p115_C PF04871.13 EFI28635.1 - 2.5 8.5 15.7 4.2 7.8 15.7 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Rootletin PF15035.6 EFI28635.1 - 3.7 7.5 13.8 9.3 6.2 13.8 1.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SLX9 PF15341.6 EFI28636.1 - 3.5e-20 72.7 11.7 4.4e-20 72.4 11.7 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 EamA PF00892.20 EFI28637.1 - 4.3e-09 36.7 34.7 2.6e-07 30.9 4.2 3.2 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 EFI28637.1 - 3.9e-08 33.2 2.3 3.1e-06 26.9 0.3 2.5 2 1 0 2 2 2 2 Solute carrier family 35 UAA PF08449.11 EFI28637.1 - 3.3e-05 23.2 0.9 3.3e-05 23.2 0.9 1.7 2 0 0 2 2 2 1 UAA transporter family DUF3955 PF13127.6 EFI28637.1 - 7.5e-05 22.5 1.3 7.5e-05 22.5 1.3 4.0 5 0 0 5 5 5 1 Protein of unknown function (DUF3955) TPT PF03151.16 EFI28637.1 - 0.11 11.9 7.8 0.68 9.2 2.2 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF2070 PF09843.9 EFI28637.1 - 8.4 4.6 11.7 0.22 9.8 0.9 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_transf_8 PF01501.20 EFI28638.1 - 2.1e-20 73.4 0.0 3.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EFI28638.1 - 0.00029 20.3 0.0 0.00063 19.2 0.0 1.4 2 0 0 2 2 2 1 Mannosyltransferase putative Ribosomal_S28e PF01200.18 EFI28639.1 - 8.9e-33 112.1 1.5 9.9e-33 111.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Phostensin_N PF13916.6 EFI28639.1 - 0.082 13.3 0.0 0.086 13.2 0.0 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Ribosomal_L11_N PF03946.14 EFI28641.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Aconitase PF00330.20 EFI28644.1 - 4.9e-150 500.5 0.0 6.2e-150 500.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EFI28644.1 - 8.7e-38 129.6 0.0 1.5e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_hydro_3_C PF01915.22 EFI28645.1 - 5.5e-37 127.7 0.5 7.3e-32 111.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EFI28645.1 - 1.1e-29 103.9 0.0 3.1e-29 102.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EFI28645.1 - 1.1e-20 73.5 0.0 2.3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.18 EFI28645.1 - 5.5e-14 51.8 11.5 2.1e-13 50.0 11.5 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Chromo PF00385.24 EFI28646.1 - 1.4e-08 34.6 3.6 3.4e-08 33.3 3.6 1.8 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Oxidored_q2 PF00420.24 EFI28647.1 - 0.29 10.8 0.2 0.48 10.1 0.2 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Atg14 PF10186.9 EFI28649.1 - 2.4e-12 46.6 7.7 7.1e-11 41.8 7.6 2.9 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Pex2_Pex12 PF04757.14 EFI28650.1 - 1.6e-25 90.1 3.2 2.8e-25 89.3 3.2 1.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EFI28650.1 - 1.3e-10 40.9 4.6 1.9e-10 40.4 4.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EFI28650.1 - 4.9e-09 35.9 6.6 7.5e-09 35.3 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EFI28650.1 - 1.4e-08 34.4 5.5 2.3e-08 33.8 5.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EFI28650.1 - 3.1e-08 33.3 6.6 5e-08 32.7 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EFI28650.1 - 4e-08 33.5 9.0 6.6e-08 32.8 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EFI28650.1 - 4.5e-07 29.8 3.1 1.1e-06 28.5 3.1 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EFI28650.1 - 4e-06 26.7 6.0 6.5e-06 26.0 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EFI28650.1 - 6.2e-06 26.4 5.3 1.4e-05 25.3 5.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EFI28650.1 - 0.0083 16.3 6.8 0.02 15.1 6.8 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EFI28650.1 - 0.018 15.2 4.6 0.034 14.3 4.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EFI28650.1 - 0.02 14.9 1.8 0.039 14.0 1.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EFI28650.1 - 0.073 13.0 2.5 0.14 12.1 2.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TerY_C PF15616.6 EFI28650.1 - 0.09 12.9 1.6 0.25 11.5 1.5 1.7 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_4 PF14570.6 EFI28650.1 - 0.47 10.3 5.3 0.87 9.4 5.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EFI28650.1 - 0.53 10.1 2.8 1.4 8.7 2.8 1.8 1 1 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 EFI28650.1 - 2.7 8.3 7.8 7.4 6.9 7.9 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain LSM PF01423.22 EFI28651.1 - 2e-14 53.0 0.3 2.7e-14 52.6 0.3 1.3 1 1 0 1 1 1 1 LSM domain Hfq PF17209.3 EFI28651.1 - 0.0027 17.3 0.2 0.0046 16.6 0.2 1.4 1 0 0 1 1 1 1 Hfq protein HATPase_c PF02518.26 EFI28652.1 - 4.7e-30 104.4 0.0 9.9e-29 100.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EFI28652.1 - 3.5e-19 69.0 0.0 3.5e-17 62.6 0.0 2.7 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.6 EFI28652.1 - 1.2e-17 64.8 1.3 1.5e-15 58.0 0.5 2.9 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.25 EFI28652.1 - 2.6e-14 53.0 0.1 1.2e-13 50.9 0.0 2.4 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EFI28652.1 - 4.1e-09 36.8 0.0 1.4e-08 35.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EFI28652.1 - 9.3e-09 36.0 0.1 5.5e-08 33.5 0.0 2.5 2 0 0 2 2 1 1 GAF domain Pkinase PF00069.25 EFI28652.1 - 4.1e-05 23.1 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.6 EFI28652.1 - 8.1e-05 23.0 0.0 0.0002 21.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain DUF3369 PF11849.8 EFI28652.1 - 0.0024 18.1 0.2 0.015 15.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3369) Pkinase_Tyr PF07714.17 EFI28652.1 - 0.0041 16.4 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_5 PF07728.14 EFI28652.1 - 0.02 14.9 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EFI28652.1 - 0.022 14.2 0.2 5.3 6.4 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein HATPase_c_3 PF13589.6 EFI28652.1 - 0.024 14.5 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NACHT PF05729.12 EFI28652.1 - 0.052 13.5 2.3 0.2 11.6 2.3 2.1 1 1 0 1 1 1 0 NACHT domain TPR_12 PF13424.6 EFI28652.1 - 0.18 12.1 5.9 0.29 11.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat HMG_box PF00505.19 EFI28653.1 - 4.5e-13 49.4 0.1 9.5e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EFI28653.1 - 4e-06 27.3 0.1 7.6e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain QueH PF02677.14 EFI28653.1 - 0.09 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH Arm PF00514.23 EFI28654.1 - 8.4e-66 216.2 33.4 4.9e-13 48.6 0.1 11.6 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EFI28654.1 - 1.2e-17 64.0 9.6 0.00093 19.7 0.3 7.6 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 EFI28654.1 - 1.6e-16 60.4 4.2 0.025 15.0 0.2 6.7 4 3 2 6 6 6 4 HEAT repeats HEAT PF02985.22 EFI28654.1 - 7.9e-13 47.5 12.8 0.19 12.1 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 EFI28654.1 - 2.9e-11 43.3 8.6 1.7e-08 34.3 0.8 2.3 2 0 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 EFI28654.1 - 2.3e-10 39.7 10.2 3.1e-08 32.6 0.1 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 EFI28654.1 - 2.9e-08 32.3 2.2 5.3e-08 31.5 2.2 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EFI28654.1 - 1.2e-07 31.3 8.1 0.00022 20.6 3.8 4.1 2 1 2 4 4 4 3 V-ATPase subunit H Cnd1 PF12717.7 EFI28654.1 - 4.8e-05 23.4 8.9 0.011 15.7 0.1 4.9 1 1 5 6 6 6 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EFI28654.1 - 0.0015 18.5 7.1 1.4 8.9 0.0 3.7 2 2 2 4 4 4 2 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 EFI28654.1 - 0.003 18.1 3.0 1.5e+02 3.5 0.0 6.6 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.8 EFI28654.1 - 0.0035 17.4 3.6 33 4.6 0.2 4.8 3 2 3 6 6 6 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 EFI28654.1 - 0.039 14.0 2.6 0.21 11.6 0.3 3.2 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Vac14_Fab1_bd PF12755.7 EFI28654.1 - 0.042 14.4 0.0 14 6.3 0.0 3.4 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region RasGEF_N_2 PF14663.6 EFI28654.1 - 2.3 8.7 4.3 42 4.6 0.1 3.8 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PIF1 PF05970.14 EFI28655.1 - 5.6e-61 206.7 0.0 6.9e-45 153.8 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EFI28655.1 - 1.7e-21 76.9 0.0 3.6e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cauli_VI PF01693.16 EFI28655.1 - 5.5e-20 71.4 0.7 1.3e-19 70.2 0.7 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_19 PF13245.6 EFI28655.1 - 3.7e-07 30.6 0.0 1.5e-06 28.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 EFI28655.1 - 0.00014 19.9 0.4 0.00064 17.8 0.0 1.9 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EFI28655.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EFI28655.1 - 0.00065 20.0 0.1 0.005 17.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EFI28655.1 - 0.00077 19.3 0.5 0.9 9.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EFI28655.1 - 0.0011 19.4 0.6 0.0025 18.2 0.1 1.8 2 0 0 2 2 1 1 AAA ATPase domain SH3_13 PF18335.1 EFI28655.1 - 0.0028 17.5 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain PhoH PF02562.16 EFI28655.1 - 0.0076 15.7 0.1 0.063 12.7 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.14 EFI28655.1 - 0.023 14.5 0.2 4.1 7.2 0.0 3.0 2 1 0 2 2 2 0 Helicase AAA_7 PF12775.7 EFI28655.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EFI28655.1 - 0.051 14.1 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EFI28655.1 - 0.08 12.9 0.2 1.1 9.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EFI28655.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF4926 PF16277.5 EFI28655.1 - 0.12 11.8 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) RsgA_GTPase PF03193.16 EFI28655.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Arm-DNA-bind_4 PF14657.6 EFI28655.1 - 0.48 10.2 3.8 0.16 11.8 0.6 1.9 2 0 0 2 2 2 0 Arm DNA-binding domain Glyco_hydro_72 PF03198.14 EFI28656.1 - 6.8e-94 314.6 0.0 1e-93 314.1 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EFI28656.1 - 3.3e-16 59.7 0.1 8.5e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EFI28656.1 - 0.0094 15.4 0.0 0.022 14.2 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SUR7 PF06687.12 EFI28657.1 - 7.5e-17 61.7 4.9 9e-17 61.4 4.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF805 PF05656.14 EFI28657.1 - 0.34 11.4 2.2 1.1 9.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF3917 PF13055.6 EFI28657.1 - 3.4 8.2 7.8 0.36 11.3 1.4 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF3917) DUF2721 PF11026.8 EFI28657.1 - 5.4 6.9 9.9 3.6 7.5 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RIC1 PF07064.13 EFI28658.1 - 6.5e-95 317.3 1.0 1.1e-94 316.5 1.0 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EFI28658.1 - 0.00066 19.9 0.0 0.023 15.0 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PRELI PF04707.14 EFI28659.1 - 4.6e-34 117.5 0.0 5.7e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Lactamase_B_2 PF12706.7 EFI28660.1 - 5.7e-27 94.6 0.1 7.4e-18 64.8 0.1 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EFI28660.1 - 0.00029 20.9 0.4 0.00076 19.5 0.2 1.8 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily PIN PF01850.21 EFI28660.1 - 0.023 15.2 0.0 0.093 13.2 0.0 1.9 1 1 1 2 2 2 0 PIN domain Lactamase_B_6 PF16661.5 EFI28660.1 - 0.16 11.4 0.0 0.42 10.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Pkinase PF00069.25 EFI28661.1 - 4.7e-64 216.3 0.0 8.7e-64 215.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28661.1 - 7e-35 120.5 0.0 2.5e-33 115.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EFI28661.1 - 6e-06 25.8 0.5 3.9e-05 23.1 0.5 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EFI28661.1 - 0.00026 21.0 0.0 0.0066 16.4 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EFI28661.1 - 0.002 17.0 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EFI28661.1 - 0.0021 17.2 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EFI28661.1 - 0.039 13.3 0.1 0.08 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EFI28661.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EFI28661.1 - 1.4 7.8 4.0 0.35 9.7 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain LAG1-DNAbind PF09271.11 EFI28662.1 - 4e-27 95.7 0.1 3e-24 86.4 0.1 2.4 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 EFI28662.1 - 1.4e-22 80.6 0.0 3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DEAD PF00270.29 EFI28664.1 - 4e-16 59.3 0.0 8.2e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EFI28664.1 - 2.2e-07 31.2 0.0 4.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.24 EFI28665.1 - 3.3e-105 352.5 12.5 3.9e-105 352.3 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EFI28665.1 - 3.6e-27 95.2 26.2 1.1e-21 77.2 4.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1156 PF06634.12 EFI28665.1 - 0.86 9.8 2.9 0.86 9.8 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1156) TRAPPC-Trs85 PF12739.7 EFI28666.1 - 2.3e-35 122.4 0.0 4.9e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 EFI28666.1 - 0.004 14.6 0.0 0.0058 14.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit WW PF00397.26 EFI28667.1 - 4.1e-05 23.6 0.1 4.1e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 EFI28667.1 - 0.058 13.4 11.5 0.23 11.5 11.6 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TatD_DNase PF01026.21 EFI28668.1 - 1.4e-32 113.1 0.0 1.4e-29 103.2 0.0 2.2 1 1 1 2 2 2 2 TatD related DNase Glyco_transf_21 PF13506.6 EFI28669.1 - 4.4e-28 97.9 0.3 5.6e-22 78.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EFI28669.1 - 3.8e-16 59.7 0.1 5.2e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EFI28669.1 - 1.9e-05 24.6 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 MMR_HSR1 PF01926.23 EFI28670.1 - 2.1e-15 56.8 0.0 1.9e-14 53.7 0.0 2.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EFI28670.1 - 3.6e-07 30.2 0.1 0.0022 17.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EFI28670.1 - 1.7e-05 24.4 0.0 8.2e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EFI28670.1 - 0.00029 20.2 0.8 0.00048 19.5 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EFI28670.1 - 0.091 12.8 0.1 0.28 11.2 0.1 1.9 1 0 0 1 1 1 0 Dynamin family Pkinase PF00069.25 EFI28671.1 - 1.1e-17 64.3 0.0 3.5e-15 56.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28671.1 - 6.4e-10 38.7 0.0 6.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EFI28671.1 - 0.15 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Med7 PF05983.11 EFI28672.1 - 4.4e-50 170.4 0.4 4.4e-50 170.4 0.4 1.5 2 0 0 2 2 2 1 MED7 protein nsp8 PF08717.10 EFI28672.1 - 0.063 13.2 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 nsp8 replicase U3_assoc_6 PF08640.11 EFI28672.1 - 0.075 13.1 0.1 19 5.4 0.0 2.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Herpes_UL25 PF01499.16 EFI28672.1 - 0.58 8.6 3.2 0.81 8.1 3.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family AMP-binding PF00501.28 EFI28673.1 - 2e-78 263.9 0.0 1.5e-77 261.0 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EFI28673.1 - 5.7e-13 49.6 0.1 1.7e-12 48.1 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPP1-like PF11833.8 EFI28674.1 - 6.3 6.4 7.2 15 5.2 7.2 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3591 PF12157.8 EFI28675.1 - 1.1e-177 591.2 2.1 1.8e-177 590.5 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EFI28675.1 - 0.00013 21.7 2.6 0.00027 20.7 2.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EFI28675.1 - 0.83 9.8 3.3 1.5 9.1 3.3 1.3 1 0 0 1 1 1 0 Zinc knuckle ParA PF10609.9 EFI28676.1 - 1.8e-90 302.7 0.0 2e-90 302.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EFI28676.1 - 7.1e-08 32.6 0.0 1.7e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EFI28676.1 - 1.1e-05 24.8 0.2 0.00099 18.4 0.1 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 EFI28676.1 - 1.5e-05 24.9 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EFI28676.1 - 0.00038 19.8 0.1 0.0064 15.8 0.1 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.6 EFI28676.1 - 0.017 15.0 0.2 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EFI28676.1 - 0.051 13.1 0.2 0.14 11.7 0.2 1.7 1 0 0 1 1 1 0 AAA domain Desulfoferrod_N PF06397.12 EFI28676.1 - 0.056 13.1 1.0 0.13 11.9 1.0 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain RsgA_GTPase PF03193.16 EFI28676.1 - 0.1 12.5 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 EFI28676.1 - 0.18 10.9 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Homeodomain PF00046.29 EFI28677.1 - 3.7e-16 58.7 2.7 9.9e-16 57.3 2.7 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EFI28677.1 - 8.3e-09 35.2 0.9 3.5e-08 33.2 0.9 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 EFI28677.1 - 0.0045 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Chalcone_N PF18232.1 EFI28677.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Chalcone isomerase N-terminal domain DUF1741 PF08427.10 EFI28678.1 - 0.16 11.6 0.1 0.24 11.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) zf-C2H2_8 PF15909.5 EFI28679.1 - 0.00021 21.5 0.9 0.00051 20.3 0.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EFI28679.1 - 0.11 13.4 0.6 1 10.4 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Transthyretin PF00576.21 EFI28680.1 - 1.4e-35 122.3 0.0 1.6e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Methyltransf_23 PF13489.6 EFI28681.1 - 5e-06 26.5 0.0 7.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EFI28681.1 - 1.1e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EFI28681.1 - 1.9e-05 25.3 0.0 3.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EFI28681.1 - 8e-05 22.0 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EFI28681.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EFI28681.1 - 0.0044 16.6 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EFI28681.1 - 0.024 15.3 0.0 0.046 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EFI28681.1 - 0.033 14.3 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EFI28681.1 - 0.14 12.8 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BEX PF04538.12 EFI28682.1 - 0.048 14.3 0.7 1.5 9.4 0.7 2.1 1 1 0 1 1 1 0 Brain expressed X-linked like family RhoGEF PF00621.20 EFI28683.1 - 1.1e-06 29.1 0.0 1.8e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Aminotran_4 PF01063.19 EFI28684.1 - 8.4e-21 74.8 0.0 1.1e-20 74.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV NIPSNAP PF07978.13 EFI28685.1 - 0.0036 17.5 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 NIPSNAP Proteasome PF00227.26 EFI28686.1 - 3e-36 124.7 0.0 3.4e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MoaC PF01967.21 EFI28687.1 - 7.5e-48 162.1 0.4 1.3e-47 161.3 0.4 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EFI28687.1 - 8.7e-40 135.6 0.0 1.5e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EFI28687.1 - 4.8e-29 101.9 0.0 7.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EFI28687.1 - 1.2e-05 25.6 0.0 3.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EFI28687.1 - 0.0076 16.4 0.0 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 4Fe-4S single cluster domain V-SNARE_C PF12352.8 EFI28688.1 - 7.3e-15 55.0 2.6 7.3e-15 55.0 2.6 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus FAM184 PF15665.5 EFI28688.1 - 0.0009 19.1 3.8 0.0009 19.1 3.8 1.7 1 1 0 1 1 1 1 Family with sequence similarity 184, A and B APG6_N PF17675.1 EFI28688.1 - 0.0066 17.0 6.0 0.0066 17.0 6.0 2.1 1 1 0 2 2 2 1 Apg6 coiled-coil region HrpB7 PF09486.10 EFI28688.1 - 0.03 14.7 8.3 0.04 14.3 7.4 1.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Spectrin PF00435.21 EFI28688.1 - 0.044 14.3 4.6 1.1 9.8 0.3 2.6 1 1 1 2 2 2 0 Spectrin repeat Sec20 PF03908.13 EFI28688.1 - 0.098 12.6 1.4 0.97 9.4 0.0 2.6 2 1 1 3 3 3 0 Sec20 Vip3A_N PF12495.8 EFI28688.1 - 0.15 12.0 0.8 6.5 6.6 0.8 2.2 1 1 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Ax_dynein_light PF10211.9 EFI28688.1 - 0.17 11.8 3.9 0.083 12.8 1.8 1.6 2 0 0 2 2 2 0 Axonemal dynein light chain kleA_kleC PF17383.2 EFI28688.1 - 0.17 12.2 2.4 0.27 11.6 0.3 2.4 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A SHE3 PF17078.5 EFI28688.1 - 0.17 11.6 6.1 0.17 11.6 4.6 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 EFI28688.1 - 0.2 9.5 3.5 0.34 8.8 3.4 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 EFI28688.1 - 0.27 11.7 4.2 0.23 11.9 1.4 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 EFI28688.1 - 0.3 10.4 7.1 1.2 8.4 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3958 PF13125.6 EFI28688.1 - 0.4 10.9 4.3 0.29 11.4 2.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) EzrA PF06160.12 EFI28688.1 - 0.56 8.3 5.9 1.4 7.0 0.3 2.5 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Vir_act_alpha_C PF10400.9 EFI28688.1 - 0.62 10.8 5.2 0.65 10.7 2.0 2.6 1 1 1 2 2 2 0 Virulence activator alpha C-term Nup54 PF13874.6 EFI28688.1 - 0.75 9.9 5.6 2.7 8.1 0.8 2.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 EFI28688.1 - 1 8.2 6.9 1.3 7.8 5.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 EFI28688.1 - 1.4 9.6 8.2 2.2 8.9 2.5 3.0 3 0 0 3 3 3 0 SlyX YgaB PF14182.6 EFI28688.1 - 1.7 9.1 4.8 5 7.6 0.6 3.1 1 1 2 3 3 3 0 YgaB-like protein Lebercilin PF15619.6 EFI28688.1 - 2.7 7.6 11.4 1.8 8.2 7.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2358 PF10184.9 EFI28689.1 - 0.0013 18.9 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EFI28689.1 - 0.067 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 EFI28690.1 - 0.0076 16.9 0.0 0.033 14.8 0.0 2.0 1 1 1 2 2 2 1 SnoaL-like domain DUF2358 PF10184.9 EFI28690.1 - 0.026 14.8 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) ABC_membrane PF00664.23 EFI28691.1 - 2.2e-53 181.7 20.0 7.8e-34 117.6 0.9 2.7 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EFI28691.1 - 8.6e-47 159.1 1.5 7.8e-30 104.2 0.2 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EFI28691.1 - 3e-10 39.9 5.2 0.00011 21.7 0.2 4.4 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EFI28691.1 - 3.9e-08 32.9 1.4 0.0094 15.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EFI28691.1 - 1.2e-07 31.0 0.1 0.0018 17.4 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 EFI28691.1 - 4e-06 27.5 0.4 0.0061 17.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EFI28691.1 - 1e-05 25.9 0.3 0.16 12.3 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EFI28691.1 - 1.1e-05 25.4 1.9 0.53 10.0 0.0 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EFI28691.1 - 2.9e-05 24.5 0.8 0.095 13.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EFI28691.1 - 7.8e-05 22.7 1.6 0.16 12.0 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EFI28691.1 - 0.00021 20.6 0.1 0.19 11.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.23 EFI28691.1 - 0.00024 21.2 1.3 0.091 12.8 0.1 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 EFI28691.1 - 0.00029 20.3 0.6 0.53 9.6 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 EFI28691.1 - 0.00034 20.8 3.6 0.008 16.3 0.3 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 EFI28691.1 - 0.00035 20.2 0.5 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EFI28691.1 - 0.00041 20.3 0.2 0.69 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EFI28691.1 - 0.00045 19.8 0.7 0.19 11.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EFI28691.1 - 0.0041 17.3 0.0 5.2 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 EFI28691.1 - 0.0041 16.0 0.4 0.92 8.2 0.0 2.4 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_18 PF13238.6 EFI28691.1 - 0.012 16.2 0.1 7.1 7.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EFI28691.1 - 0.014 15.4 0.3 3 7.8 0.0 3.0 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 EFI28691.1 - 0.017 14.9 0.6 9.3 5.8 0.0 2.7 2 1 0 3 3 3 0 AAA ATPase domain Viral_helicase1 PF01443.18 EFI28691.1 - 0.017 14.8 0.1 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 EFI28691.1 - 0.02 13.8 0.6 4.9 5.9 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 EFI28691.1 - 0.027 13.6 0.2 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EFI28691.1 - 0.029 14.4 0.0 9.3 6.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EFI28691.1 - 0.058 13.1 1.6 12 5.5 0.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EFI28691.1 - 0.077 12.5 0.1 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EFI28691.1 - 0.08 12.8 0.0 20 5.0 0.0 2.8 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea FKBP_N_2 PF18023.1 EFI28691.1 - 0.088 12.9 0.2 0.2 11.8 0.2 1.5 1 0 0 1 1 1 0 BDBT FKBP like N-terminal AAA_5 PF07728.14 EFI28691.1 - 0.097 12.7 0.6 16 5.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EFI28691.1 - 0.11 11.7 0.2 3.7 6.7 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 EFI28691.1 - 0.21 11.5 1.9 3 7.7 0.1 3.1 3 0 0 3 3 3 0 NTPase MeaB PF03308.16 EFI28691.1 - 0.23 10.4 0.7 0.84 8.6 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 EFI28691.1 - 0.3 10.3 1.4 3.3 6.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 EFI28691.1 - 0.72 9.8 2.6 12 5.7 0.1 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Lum_binding PF00677.17 EFI28692.1 - 1.2e-44 150.2 0.2 2.6e-21 75.4 0.1 2.6 2 0 0 2 2 2 2 Lumazine binding domain RNase_H2_suC PF08615.11 EFI28692.1 - 0.15 12.2 2.5 0.37 11.0 2.3 1.8 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Activator-TraM PF11657.8 EFI28692.1 - 0.17 11.7 0.4 0.38 10.6 0.4 1.5 1 0 0 1 1 1 0 Transcriptional activator TraM Myosin_head PF00063.21 EFI28693.1 - 3.8e-223 742.6 0.2 1.4e-221 737.4 0.2 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EFI28693.1 - 2e-54 184.1 0.0 3.8e-54 183.2 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding UNC45-central PF11701.8 EFI28693.1 - 6.4e-17 61.9 1.0 2.9e-16 59.8 0.6 2.4 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central SH3_1 PF00018.28 EFI28693.1 - 2.1e-07 30.5 1.1 4.2e-07 29.5 1.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EFI28693.1 - 3.8e-07 29.9 0.3 8e-07 28.8 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EFI28693.1 - 1.2e-05 24.9 0.0 2.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EFI28693.1 - 0.0011 19.2 0.5 0.0025 18.1 0.5 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.12 EFI28693.1 - 0.016 14.8 0.4 6.8 6.2 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EFI28693.1 - 0.055 13.8 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EFI28693.1 - 0.14 12.0 0.2 0.68 9.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Trns_repr_metal PF02583.17 EFI28693.1 - 0.18 12.2 0.0 0.6 10.5 0.0 1.9 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor ACT_7 PF13840.6 EFI28694.1 - 1.1e-17 63.6 0.0 2e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain Peptidase_M24 PF00557.24 EFI28695.1 - 2.5e-41 141.7 0.0 3.8e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Bromodomain PF00439.25 EFI28695.1 - 8.9e-35 118.6 1.0 5.9e-18 64.7 0.0 2.7 2 0 0 2 2 2 2 Bromodomain RNA_polI_A34 PF08208.11 EFI28695.1 - 7.2 6.6 23.3 1.8 8.6 11.8 3.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3381 PF11861.8 EFI28695.1 - 8.3 6.2 15.5 4.3 7.1 8.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Pkinase PF00069.25 EFI28696.1 - 1.5e-72 244.1 0.0 2e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EFI28696.1 - 6.3e-53 179.7 0.0 9e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EFI28696.1 - 1.4e-05 24.1 0.0 2.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EFI28696.1 - 5.3e-05 22.7 0.0 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EFI28696.1 - 0.00085 18.4 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 2 Haspin like kinase domain DUF1241 PF06840.11 EFI28696.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) MscS_porin PF12795.7 EFI28696.1 - 0.068 12.7 0.1 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain PBP1_TM PF14812.6 EFI28696.1 - 0.21 12.0 3.1 4.3 7.8 2.1 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAD_binding_2 PF03446.15 EFI28697.1 - 3.2e-20 72.9 0.0 7.4e-20 71.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EFI28697.1 - 8.6e-11 42.1 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EFI28697.1 - 8.1e-08 32.4 0.0 1.8e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EFI28697.1 - 4.2e-07 30.4 0.1 9.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EFI28697.1 - 0.00036 19.9 0.0 0.00064 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EFI28697.1 - 0.0074 16.3 0.1 0.013 15.4 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_3 PF03447.16 EFI28697.1 - 0.0085 16.7 0.1 0.018 15.7 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ThiF PF00899.21 EFI28697.1 - 0.018 14.4 0.2 0.059 12.7 0.2 1.8 1 1 0 1 1 1 0 ThiF family GFO_IDH_MocA PF01408.22 EFI28697.1 - 0.018 15.9 0.1 0.029 15.2 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EFI28697.1 - 0.038 14.2 0.1 0.075 13.3 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PAH PF02671.21 EFI28698.1 - 1.7e-13 50.4 1.2 1e-07 31.9 0.5 2.6 2 1 0 2 2 2 2 Paired amphipathic helix repeat PaaX_C PF08223.11 EFI28698.1 - 0.045 14.0 0.8 0.77 10.1 0.1 2.7 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain UQ_con PF00179.26 EFI28700.1 - 5.9e-26 90.8 0.0 5.6e-25 87.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EFI28700.1 - 0.0004 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 UEV domain DUF5320 PF17253.2 EFI28700.1 - 0.049 14.7 8.0 0.17 13.0 6.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) FoP_duplication PF13865.6 EFI28700.1 - 5.2 7.7 10.4 6 7.5 0.8 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 FXMRP1_C_core PF12235.8 EFI28700.1 - 6 7.5 5.6 19 5.9 2.6 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal TFIIA PF03153.13 EFI28701.1 - 3.4 7.6 22.6 8.5 6.3 15.8 2.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 EFI28703.1 - 2e-43 148.6 9.1 1.5e-37 129.3 0.6 2.7 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EFI28703.1 - 1.4e-26 93.2 0.0 2.4e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EFI28703.1 - 9.1e-17 61.0 8.4 9.1e-17 61.0 8.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 EFI28703.1 - 0.024 14.8 4.4 0.078 13.2 4.4 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger IBR PF01485.21 EFI28703.1 - 0.3 11.3 10.4 0.22 11.8 5.7 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Ribosomal_L1 PF00687.21 EFI28704.1 - 1.5e-19 70.5 0.1 6.9e-17 61.9 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family dsrm PF00035.26 EFI28705.1 - 1e-12 48.5 0.1 1.2e-12 48.3 0.1 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif MMM1 PF10296.9 EFI28706.1 - 2e-08 33.7 0.0 3.6e-07 29.6 0.0 2.8 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EFI28706.1 - 0.032 14.7 0.0 1.1 9.8 0.0 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain DSHCT PF08148.12 EFI28708.1 - 6.2e-52 175.6 0.4 1.5e-51 174.3 0.4 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EFI28708.1 - 2.9e-27 95.1 0.0 5.8e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EFI28708.1 - 1.4e-25 90.8 0.0 2.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EFI28708.1 - 2.2e-16 60.1 0.1 6.1e-16 58.7 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EFI28708.1 - 1e-05 25.6 0.1 1.9e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EFI28708.1 - 6.5e-05 23.2 0.0 0.00021 21.6 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 EFI28708.1 - 0.056 13.3 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea WLM PF08325.10 EFI28710.1 - 1.1e-52 178.9 0.0 1.6e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EFI28710.1 - 5.6e-05 22.4 2.1 5.6e-05 22.4 2.1 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others SVIP PF15811.5 EFI28710.1 - 0.0002 21.7 8.3 0.0046 17.4 0.0 2.4 2 0 0 2 2 2 1 Small VCP/p97-interacting protein DUF45 PF01863.17 EFI28710.1 - 0.00071 19.7 0.2 0.0053 16.8 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF45 DZR PF12773.7 EFI28710.1 - 0.001 19.0 7.4 0.002 18.1 7.4 1.5 1 0 0 1 1 1 1 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 EFI28710.1 - 1.6 8.7 6.8 0.47 10.4 0.8 2.9 1 1 2 3 3 3 0 Putative transposase DNA-binding domain zf-piccolo PF05715.13 EFI28710.1 - 8.1 6.7 11.0 1.6 8.9 6.4 2.2 2 1 0 2 2 2 0 Piccolo Zn-finger RicinB_lectin_2 PF14200.6 EFI28711.1 - 0.0042 17.8 0.0 0.18 12.6 0.0 2.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like NIF PF03031.18 EFI28712.1 - 1.3e-24 86.8 0.0 1.4e-21 76.9 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase DUF4692 PF15763.5 EFI28712.1 - 0.0057 17.1 6.4 0.07 13.6 0.3 2.6 2 0 0 2 2 2 2 Regulator of human erythroid cell expansion (RHEX) IMUP PF15761.5 EFI28712.1 - 2.4 8.9 19.2 0.37 11.5 5.1 3.1 3 0 0 3 3 3 0 Immortalisation up-regulated protein FAM104 PF15434.6 EFI28712.1 - 3.6 8.2 8.3 0.61 10.7 1.9 2.5 2 0 0 2 2 2 0 Family 104 Inositol_P PF00459.25 EFI28714.1 - 8.7e-52 176.3 0.6 4.2e-51 174.0 0.6 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family CPSase_L_D2 PF02786.17 EFI28715.1 - 4.2e-72 242.1 0.0 8e-72 241.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EFI28715.1 - 1.3e-46 157.7 0.4 4.8e-46 155.9 0.1 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EFI28715.1 - 2.2e-30 104.9 0.0 6.4e-29 100.2 0.0 2.4 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain ADH_zinc_N PF00107.26 EFI28715.1 - 4.2e-17 62.3 0.3 5.7e-16 58.7 0.0 2.9 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Biotin_lipoyl PF00364.22 EFI28715.1 - 4.5e-16 58.4 1.9 1.4e-15 56.9 1.9 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EFI28715.1 - 7.1e-08 32.2 0.1 0.00028 20.6 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ADH_N PF08240.12 EFI28715.1 - 2.6e-07 30.5 0.0 1.3e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EFI28715.1 - 4.5e-06 27.7 0.0 7.5e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Dala_Dala_lig_C PF07478.13 EFI28715.1 - 5.7e-06 26.0 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 EFI28715.1 - 0.00059 20.5 0.4 0.62 10.8 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 EFI28715.1 - 0.00076 19.4 0.3 0.045 13.7 0.3 2.6 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EFI28715.1 - 0.026 14.4 0.6 0.054 13.4 0.6 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 EFI28715.1 - 0.038 13.2 0.3 4.3 6.5 0.0 2.9 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PK_C PF02887.16 EFI28715.1 - 0.37 11.0 1.3 40 4.5 0.0 3.7 4 0 0 4 4 4 0 Pyruvate kinase, alpha/beta domain Calreticulin PF00262.18 EFI28716.1 - 3.8e-161 536.0 9.7 5.4e-161 535.5 9.7 1.2 1 0 0 1 1 1 1 Calreticulin family SAM_PNT PF02198.16 EFI28716.1 - 0.078 12.9 0.1 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain GTP_EFTU PF00009.27 EFI28717.1 - 1e-43 149.2 0.0 1.7e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EFI28717.1 - 3.8e-38 130.8 7.1 5.9e-38 130.2 7.1 1.3 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EFI28717.1 - 6.2e-23 80.9 0.0 1.4e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EFI28717.1 - 7.8e-22 77.1 0.0 1.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EFI28717.1 - 3.5e-08 33.7 0.0 7.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EFI28717.1 - 3.7e-06 27.0 0.1 1.1e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EFI28717.1 - 1.9e-05 24.6 0.0 5.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 EFI28717.1 - 0.0088 15.5 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EFI28717.1 - 0.03 13.9 0.1 0.07 12.7 0.1 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF5645 PF18713.1 EFI28717.1 - 0.092 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) Dynamin_N PF00350.23 EFI28717.1 - 0.12 12.4 0.1 9 6.3 0.0 2.4 1 1 1 2 2 2 0 Dynamin family GFA PF04828.14 EFI28718.1 - 1.2e-13 51.2 0.4 1.7e-13 50.7 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sgf11 PF08209.11 EFI28718.1 - 0.37 10.4 4.8 7.6 6.2 0.9 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Nop14 PF04147.12 EFI28720.1 - 3.7 5.6 7.2 5 5.2 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family FSA_C PF10479.9 EFI28721.1 - 1.1 7.3 16.6 1.2 7.2 16.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus F-box-like PF12937.7 EFI28722.1 - 0.00024 20.9 0.7 0.00077 19.3 0.7 1.9 1 1 0 1 1 1 1 F-box-like F-box_5 PF18511.1 EFI28722.1 - 0.0033 17.0 0.1 0.0087 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 EFI28722.1 - 6.2 6.8 7.1 21 5.1 0.4 3.2 3 0 0 3 3 3 0 F-box domain zf-C2H2_jaz PF12171.8 EFI28724.1 - 6.2e-14 51.9 27.1 0.00076 19.7 1.8 5.2 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EFI28724.1 - 2.4e-13 49.7 21.9 0.034 15.0 0.5 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 EFI28724.1 - 2.9e-09 36.9 25.8 0.0099 16.3 1.3 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EFI28724.1 - 0.00026 21.3 14.4 0.064 13.6 8.7 3.2 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EFI28724.1 - 0.00036 20.8 13.4 0.25 11.8 0.1 4.6 5 0 0 5 5 5 3 Zinc-finger of C2H2 type DUF4187 PF13821.6 EFI28724.1 - 0.0022 17.8 27.3 0.1 12.4 0.7 4.3 3 1 1 4 4 4 3 Domain of unknown function (DUF4187) zinc_ribbon_15 PF17032.5 EFI28724.1 - 0.014 16.1 14.2 0.078 13.7 1.5 3.0 1 1 2 3 3 3 0 zinc-ribbon family zf-C2H2_3rep PF18868.1 EFI28724.1 - 0.032 14.9 8.8 2.5 8.8 1.6 3.3 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF1272 PF06906.11 EFI28724.1 - 0.26 11.4 11.7 0.38 10.9 0.6 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1272) zf-RRPl_C4 PF17026.5 EFI28724.1 - 0.95 9.6 19.6 9.8 6.3 2.4 4.2 1 1 2 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type FYVE PF01363.21 EFI28724.1 - 1.1 9.5 19.2 1 9.5 8.0 3.3 1 1 2 3 3 3 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 EFI28724.1 - 2.5 8.2 16.6 2.9e+03 -1.7 16.6 3.6 1 1 0 1 1 1 0 zinc-ribbons Thioredoxin_7 PF13899.6 EFI28724.1 - 7.4 6.8 7.2 30 4.9 0.3 3.3 3 1 1 4 4 4 0 Thioredoxin-like DZR PF12773.7 EFI28724.1 - 8.2 6.5 18.2 17 5.5 2.6 3.8 1 1 1 2 2 2 0 Double zinc ribbon BUD22 PF09073.10 EFI28730.1 - 2.7 7.2 22.3 3 7.1 22.3 1.0 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EFI28730.1 - 4.3 6.7 23.8 5.2 6.4 23.8 1.2 1 0 0 1 1 1 0 SDA1 DUF3413 PF11893.8 EFI28731.1 - 0.011 14.9 0.1 0.011 14.9 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) DUF4131 PF13567.6 EFI28731.1 - 2.7 7.6 10.5 6.9 6.3 6.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Dscam_C PF12355.8 EFI28732.1 - 0.09 13.7 2.1 0.62 11.0 1.5 2.1 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal zf-C2H2 PF00096.26 EFI28735.1 - 2.7e-08 33.8 9.6 0.00051 20.3 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EFI28735.1 - 1.6e-05 25.1 3.2 1.6e-05 25.1 3.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EFI28735.1 - 0.00018 22.0 8.9 0.03 15.1 1.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EFI28735.1 - 3.5 7.7 5.2 0.54 10.3 0.7 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EFI28735.1 - 4.1 7.2 9.7 7.4 6.4 1.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain GTP_cyclohydroI PF01227.22 EFI28736.1 - 0.075 12.4 0.0 0.081 12.3 0.0 1.0 1 0 0 1 1 1 0 GTP cyclohydrolase I SMC_hinge PF06470.13 EFI28737.1 - 1.9e-27 95.9 0.0 9.6e-27 93.6 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 EFI28737.1 - 6.7e-25 87.8 38.0 1.6e-24 86.6 38.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EFI28737.1 - 3.7e-05 23.7 0.0 0.00013 21.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system HTH_46 PF15977.5 EFI28737.1 - 0.017 15.1 0.1 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding Csa1 PF06023.12 EFI28737.1 - 0.6 9.4 11.8 0.029 13.7 2.9 2.8 3 0 0 3 3 3 0 CRISPR-associated exonuclease Csa1 Voldacs PF03517.13 EFI28737.1 - 2.5 8.2 12.8 9.8 6.3 12.8 2.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling GBR2_CC PF18455.1 EFI28737.1 - 3.9 7.7 5.7 50 4.1 0.1 4.1 3 0 0 3 3 3 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain SMC_N PF02463.19 EFI28738.1 - 1.1e-38 132.9 0.1 2.4e-38 131.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EFI28738.1 - 8.9e-15 55.7 0.9 2.1e-14 54.5 0.9 1.6 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EFI28738.1 - 5.9e-09 36.1 0.6 1e-08 35.3 0.6 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EFI28738.1 - 3.9e-07 30.2 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EFI28738.1 - 2.3e-06 27.2 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EFI28738.1 - 0.015 15.8 2.4 0.17 12.4 2.3 2.4 1 1 0 1 1 1 0 ABC transporter APG6_N PF17675.1 EFI28738.1 - 0.16 12.5 7.7 0.55 10.8 7.7 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF87 PF01935.17 EFI28738.1 - 0.53 10.3 3.7 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Nop10p PF04135.12 EFI28739.1 - 8.9e-23 80.1 0.7 1e-22 79.9 0.7 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Senescence_reg PF04520.13 EFI28740.1 - 0.013 16.3 0.0 0.019 15.8 0.0 1.3 1 0 0 1 1 1 0 Senescence regulator PRANC PF09372.10 EFI28741.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Utp14 PF04615.13 EFI28742.1 - 4.6e-190 633.9 90.5 4.6e-190 633.9 90.5 3.1 1 1 2 3 3 3 1 Utp14 protein PspB PF06667.12 EFI28742.1 - 4.6 7.4 7.0 0.53 10.4 0.4 2.9 2 1 1 3 3 3 0 Phage shock protein B CAF1 PF04857.20 EFI28743.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease RRM_1 PF00076.22 EFI28746.1 - 1.3e-18 66.6 0.0 2.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EFI28746.1 - 0.0047 16.5 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M76 PF09768.9 EFI28753.1 - 1.1e-69 233.6 4.6 1.3e-69 233.3 4.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.6 EFI28753.1 - 0.017 14.9 0.2 0.022 14.5 0.2 1.1 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Exostosin PF03016.15 EFI28753.1 - 0.079 12.2 0.9 0.13 11.5 0.9 1.2 1 0 0 1 1 1 0 Exostosin family Peptidase_M90 PF06167.12 EFI28753.1 - 0.088 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 SprT-like PF10263.9 EFI28753.1 - 0.16 11.8 2.3 0.3 10.9 1.9 1.6 1 1 0 1 1 1 0 SprT-like family SR-25 PF10500.9 EFI28753.1 - 1.2 8.7 4.8 1.8 8.1 4.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GPI-anchored PF10342.9 EFI28754.1 - 3.5e-09 37.3 0.6 1.2e-08 35.6 0.0 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zn_clus PF00172.18 EFI28756.1 - 0.0001 22.3 12.7 0.00016 21.7 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EFI28757.1 - 3.1e-23 82.2 0.4 4.7e-23 81.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain S-antigen PF05756.11 EFI28760.1 - 0.22 11.9 4.6 0.24 11.8 4.6 1.1 1 0 0 1 1 1 0 S-antigen protein But2 PF09792.9 EFI28761.1 - 3.7e-09 37.1 0.0 5.9e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Acetyltransf_10 PF13673.7 EFI28762.1 - 2.7e-06 27.3 0.1 1.1e-05 25.3 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EFI28762.1 - 4e-06 27.0 0.0 1.8e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EFI28762.1 - 0.0002 21.7 0.0 0.0025 18.2 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EFI28762.1 - 0.058 13.5 0.1 0.49 10.5 0.0 2.4 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF2156 PF09924.9 EFI28762.1 - 0.07 12.1 0.0 1.5 7.8 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2156) CK2S PF15011.6 EFI28763.1 - 0.0044 16.9 0.3 0.0052 16.7 0.3 1.0 1 0 0 1 1 1 1 Casein Kinase 2 substrate Chitin_bind_4 PF00379.23 EFI28763.1 - 0.086 13.4 0.2 0.12 12.9 0.2 1.2 1 0 0 1 1 1 0 Insect cuticle protein MR_MLE_N PF02746.16 EFI28764.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain PRC PF05239.16 EFI28765.1 - 0.0096 16.0 0.9 2.5 8.2 0.1 2.4 1 1 1 2 2 2 2 PRC-barrel domain DUF2171 PF09939.9 EFI28765.1 - 0.081 13.2 0.1 10 6.5 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) NAR2 PF16974.5 EFI28766.1 - 0.087 12.2 0.3 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory NRIP1_repr_2 PF15688.5 EFI28767.1 - 0.19 11.6 0.1 0.2 11.5 0.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 2 Podoplanin PF05808.11 EFI28769.1 - 0.0039 17.3 0.9 0.0045 17.1 0.9 1.1 1 0 0 1 1 1 1 Podoplanin RcpB PF16971.5 EFI28769.1 - 0.26 11.2 0.8 0.31 10.9 0.8 1.1 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit Dcc1 PF09724.9 EFI28770.1 - 0.023 14.0 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 F-box PF00646.33 EFI28771.1 - 1.7e-11 43.7 12.1 1.5e-05 24.7 2.1 2.6 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 EFI28771.1 - 3.9e-08 33.1 6.8 0.00016 21.5 1.0 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EFI28772.1 - 5.8e-06 26.0 3.4 1.2e-05 25.0 3.4 1.5 1 0 0 1 1 1 1 F-box domain tRNA-synt_His PF13393.6 EFI28773.1 - 4.7e-35 121.4 0.0 2.1e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EFI28773.1 - 8.5e-10 38.7 0.1 2.6e-09 37.1 0.1 1.9 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EFI28773.1 - 4.7e-05 23.4 0.0 0.0001 22.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 EFI28773.1 - 0.046 13.2 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs HHH_8 PF14716.6 EFI28773.1 - 0.059 13.7 0.0 0.28 11.6 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain tRNA-synt_2d PF01409.20 EFI28773.1 - 0.062 12.8 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) F-box PF00646.33 EFI28774.1 - 0.00036 20.3 4.8 0.00036 20.3 4.8 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EFI28774.1 - 0.024 14.5 0.9 0.059 13.3 0.9 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EFI28777.1 - 0.00025 20.8 0.2 0.00025 20.8 0.2 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EFI28777.1 - 0.0079 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF1685 PF07939.11 EFI28779.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) Flocculin PF00624.18 EFI28783.1 - 0.13 12.5 0.7 0.28 11.5 0.7 1.4 1 0 0 1 1 1 0 Flocculin repeat PEP-CTERM PF07589.11 EFI28783.1 - 1 9.5 3.6 3.5 7.8 3.6 1.9 1 0 0 1 1 1 0 PEP-CTERM motif Podoplanin PF05808.11 EFI28784.1 - 0.0017 18.5 2.5 0.0035 17.5 2.5 1.5 1 0 0 1 1 1 1 Podoplanin Amnionless PF14828.6 EFI28784.1 - 0.0022 16.9 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Amnionless EphA2_TM PF14575.6 EFI28784.1 - 0.01 16.7 0.0 0.018 15.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.7 EFI28784.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2207 PF09972.9 EFI28784.1 - 0.014 14.1 0.0 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Flocculin PF00624.18 EFI28784.1 - 0.047 14.0 1.9 0.17 12.2 1.9 2.0 1 0 0 1 1 1 0 Flocculin repeat Herpes_gE PF02480.16 EFI28784.1 - 0.088 11.5 0.2 0.14 10.8 0.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.15 EFI28784.1 - 0.12 12.2 2.1 0.28 11.0 2.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2755 PF10954.8 EFI28784.1 - 0.14 12.1 1.1 0.23 11.4 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) CYYR1 PF10873.8 EFI28784.1 - 0.15 12.5 0.0 0.15 12.5 0.0 3.1 2 1 1 3 3 1 0 Cysteine and tyrosine-rich protein 1 FAM176 PF14851.6 EFI28784.1 - 1 9.0 2.5 15 5.2 0.0 2.3 2 0 0 2 2 2 0 FAM176 family TMEM154 PF15102.6 EFI28784.1 - 1.1 9.1 7.9 11 6.0 7.7 2.3 1 1 0 1 1 1 0 TMEM154 protein family GMC_oxred_N PF00732.19 EFI28785.1 - 1.6e-63 214.8 0.0 2.1e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EFI28785.1 - 2.2e-34 119.0 0.0 3.9e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EFI28785.1 - 3e-05 23.3 0.0 0.012 14.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EFI28785.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EFI28785.1 - 0.00011 22.3 0.0 0.00048 20.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EFI28785.1 - 0.0093 15.6 0.1 0.034 13.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EFI28785.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 EFI28785.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EFI28785.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EFI28785.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.19 EFI28786.1 - 1.6e-59 201.7 0.0 2.3e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EFI28786.1 - 4.8e-35 121.2 0.0 9.8e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EFI28786.1 - 0.00038 20.6 0.3 0.0012 19.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EFI28786.1 - 0.0048 16.0 0.1 0.0074 15.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein TrkA_N PF02254.18 EFI28786.1 - 0.045 14.0 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 EFI28786.1 - 0.047 12.8 0.1 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EFI28786.1 - 0.069 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Atg14 PF10186.9 EFI28787.1 - 1e-35 123.4 0.0 3e-23 82.4 0.0 2.9 2 1 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coprinopsis_cinerea_okayama7_130-CC3/GCA_000182895.1_CC3_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coprinopsis_cinerea_okayama7_130-CC3/GCA_000182895.1_CC3_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coprinopsis_cinerea_okayama7_130-CC3/GCA_000182895.1_CC3_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coprinopsis_cinerea_okayama7_130-CC3/GCA_000182895.1_CC3_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 19:10:08 2019 # [ok]