# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF605 PF04652.11 EAU80160.2 - 8.5 5.6 16.4 9.7 5.4 11.4 1.1 1 0 0 1 1 1 0 Vta1 like Citrate_synt PF00285.16 EAU80161.1 - 1.8e-21 76.2 0.0 2.3e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EAU80161.1 - 0.005 16.2 0.0 0.0094 15.3 0.0 1.4 1 0 0 1 1 1 1 Eclosion hormone Methyltransf_4 PF02390.12 EAU80162.1 - 1.7e-51 174.0 0.0 2.3e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAU80162.1 - 2.7e-05 24.7 0.0 5.6e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU80162.1 - 0.00029 20.8 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU80162.1 - 0.00062 20.2 0.0 0.029 14.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU80162.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU80162.1 - 0.0098 16.3 0.0 0.047 14.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAU80162.1 - 0.025 13.9 0.0 0.092 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EAU80162.1 - 0.037 13.6 0.0 0.55 9.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EAU80162.1 - 0.059 13.0 0.0 0.54 9.9 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain NAPRTase PF04095.11 EAU80163.2 - 5.6e-12 45.4 0.1 9e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase PF04095.11 EAU80168.2 - 7.4e-30 104.0 0.0 8.6e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RHH_1 PF01402.16 EAU80171.1 - 1.3 9.0 4.7 0.64 10.0 1.4 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Glyco_hydro_7 PF00840.15 EAU80190.1 - 2.1e-206 685.4 12.1 2.4e-206 685.2 8.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.15 EAU80191.2 - 5.1e-92 308.5 6.7 6.1e-92 308.2 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Notch PF00066.12 EAU80191.2 - 3.8 7.8 8.8 5.4 7.3 0.2 3.3 3 0 0 3 3 3 0 LNR domain DUF3043 PF11241.3 EAU80192.1 - 3 7.4 6.0 4.1 6.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PRC PF05239.11 EAU80198.1 - 0.0028 17.4 0.9 1.3 8.9 0.1 2.3 1 1 1 2 2 2 2 PRC-barrel domain Cache_3 PF14827.1 EAU80198.1 - 0.032 14.1 0.2 7.9 6.4 0.0 2.4 1 1 1 2 2 2 0 Sensory domain of two-component sensor kinase LTD PF00932.14 EAU80198.1 - 0.062 13.3 0.1 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 Lamin Tail Domain Baculo_DNA_bind PF04786.7 EAU80200.2 - 0.015 14.4 0.1 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 ssDNA binding protein Helicase_C PF00271.26 EAU80211.1 - 1.6e-08 34.2 0.0 4.1e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EAU80211.1 - 4.6e-08 32.2 0.0 6.3e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Sigma70_r4 PF04545.11 EAU80211.1 - 0.091 12.0 0.2 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 BBP1_C PF15272.1 EAU80214.1 - 0.019 14.5 0.5 0.91 9.0 0.0 2.4 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal AXE1 PF05448.7 EAU80217.1 - 0.035 12.6 0.3 0.057 11.9 0.2 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.4 EAU80217.1 - 0.051 12.0 0.1 0.09 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein SRP-alpha_N PF04086.8 EAU80219.2 - 0.089 12.1 2.0 0.14 11.5 1.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DEAD PF00270.24 EAU80222.2 - 4.8e-08 32.6 0.0 3e-07 30.0 0.0 2.0 1 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU80222.2 - 1.3e-07 31.3 0.0 8.7e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU80222.2 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EAU80222.2 - 0.15 11.3 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain T2SE PF00437.15 EAU80222.2 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Nucleoplasmin PF03066.10 EAU80229.1 - 0.4 10.1 8.9 0.9 9.0 6.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin TPR_10 PF13374.1 EAU80230.2 - 4.8e-60 197.9 38.9 1.5e-05 24.7 0.1 13.9 10 3 4 14 14 14 11 Tetratricopeptide repeat TPR_12 PF13424.1 EAU80230.2 - 5.1e-46 154.4 41.1 0.00096 19.0 0.1 14.7 6 5 9 15 15 14 12 Tetratricopeptide repeat TPR_17 PF13431.1 EAU80230.2 - 2.7e-28 95.7 9.5 0.36 11.1 0.0 12.3 11 0 0 11 11 11 9 Tetratricopeptide repeat CHAT PF12770.2 EAU80230.2 - 1.7e-25 89.7 0.0 2.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EAU80230.2 - 1.5e-22 78.9 31.6 0.015 14.8 0.0 13.3 5 2 9 14 14 14 11 TPR repeat TPR_16 PF13432.1 EAU80230.2 - 1.1e-18 67.3 31.0 1.4 9.7 0.0 13.9 5 2 7 13 13 13 7 Tetratricopeptide repeat Yopt PF09467.5 EAU80230.2 - 8.4e-06 25.5 0.2 30 4.5 0.0 7.5 9 0 0 9 9 9 0 Hypothetical protein Yopt TPR_2 PF07719.12 EAU80230.2 - 0.00019 21.0 25.1 2.1e+02 2.2 0.0 14.1 15 0 0 15 15 14 0 Tetratricopeptide repeat DUF4371 PF14291.1 EAU80230.2 - 0.0016 18.0 0.0 39 3.6 0.0 6.8 9 0 0 9 9 9 0 Domain of unknown function (DUF4371) Gag_MA PF01140.14 EAU80230.2 - 0.0038 17.0 3.9 56 3.5 0.0 7.5 8 3 2 11 11 10 0 Matrix protein (MA), p15 Lantibiotic_a PF14867.1 EAU80230.2 - 0.1 11.8 0.4 28 4.0 0.0 3.4 2 0 0 2 2 2 0 Lantibiotic alpha Flp_C PF05202.7 EAU80230.2 - 0.29 10.2 0.0 0.55 9.3 0.0 1.3 1 0 0 1 1 1 0 Recombinase Flp protein DnaB_bind PF10410.4 EAU80230.2 - 0.51 10.3 8.6 60 3.7 0.0 7.2 9 0 0 9 9 9 0 DnaB-helicase binding domain of primase TPR_1 PF00515.23 EAU80230.2 - 4.7 6.9 42.9 1.3e+02 2.4 0.0 16.0 21 0 0 21 21 21 0 Tetratricopeptide repeat UBA_4 PF14555.1 EAU80230.2 - 5.8 6.5 9.8 2.1e+02 1.5 0.0 6.1 6 0 0 6 6 6 0 UBA-like domain PIF1 PF05970.9 EAU80232.1 - 1.9e-25 89.6 0.1 6.4e-25 87.8 0.0 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAU80232.1 - 2.1e-08 33.9 0.0 6.4e-08 32.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU80232.1 - 0.028 14.1 1.4 0.055 13.2 0.4 1.9 2 0 0 2 2 2 0 Part of AAA domain Herpes_Helicase PF02689.9 EAU80232.1 - 0.16 9.6 0.0 0.27 8.9 0.0 1.2 1 0 0 1 1 1 0 Helicase Viral_helicase1 PF01443.13 EAU80232.1 - 0.17 11.3 0.5 0.99 8.8 0.3 2.2 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pkinase PF00069.20 EAU80233.2 - 2.1e-11 43.4 0.1 7.9e-11 41.5 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80233.2 - 2.5e-06 26.7 0.0 3.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SnoaL_2 PF12680.2 EAU80233.2 - 0.026 14.9 0.0 0.056 13.8 0.0 1.6 2 0 0 2 2 2 0 SnoaL-like domain Kinase-like PF14531.1 EAU80233.2 - 0.097 11.6 0.0 0.21 10.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like zf-C2H2_6 PF13912.1 EAU80238.2 - 0.0025 17.6 0.4 0.0025 17.6 0.3 3.0 3 1 0 3 3 3 1 C2H2-type zinc finger zf-Di19 PF05605.7 EAU80238.2 - 0.0064 16.5 3.4 0.0064 16.5 2.3 2.7 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EAU80238.2 - 0.013 15.8 4.1 0.013 15.8 2.9 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU80238.2 - 0.025 14.9 5.3 0.025 14.9 3.7 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3505 PF12013.3 EAU80238.2 - 0.035 14.3 10.3 0.31 11.2 0.5 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3505) zf-FCS PF06467.9 EAU80238.2 - 0.066 12.8 4.1 1.9 8.2 0.3 2.7 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif UPF0547 PF10571.4 EAU80238.2 - 0.083 12.5 5.1 1.3 8.7 1.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_5 PF13719.1 EAU80238.2 - 0.24 11.0 5.7 1.7 8.3 0.6 2.8 2 0 0 2 2 2 0 zinc-ribbon domain BUD22 PF09073.5 EAU80240.2 - 6.4 5.7 40.4 0.11 11.5 21.9 2.1 2 0 0 2 2 2 0 BUD22 GMC_oxred_N PF00732.14 EAU80241.2 - 1.3e-62 211.6 0.0 1.7e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU80241.2 - 3e-33 115.1 0.0 5.7e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU80241.2 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU80241.2 - 0.0022 16.9 0.0 0.0069 15.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU80241.2 - 0.0027 16.7 0.0 0.0036 16.2 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU80241.2 - 0.025 13.4 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EAU80241.2 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EAU80241.2 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Tet_JBP PF12851.2 EAU80242.2 - 0.0051 16.1 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Peptidase_C2 PF00648.16 EAU80258.2 - 6.2e-50 169.8 0.1 2.3e-36 125.3 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Peptidase_M43 PF05572.8 EAU80259.2 - 1.4e-17 63.7 0.0 2.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EAU80259.2 - 2.2e-07 31.0 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAU80259.2 - 9.8e-06 26.1 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU80259.2 - 5.9e-05 23.0 1.4 0.0001 22.3 0.9 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU80259.2 - 0.00065 19.2 0.2 0.0013 18.2 0.1 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU80259.2 - 0.018 14.7 0.2 0.038 13.7 0.1 1.5 1 1 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.3 EAU80259.2 - 0.042 13.1 3.0 0.044 13.1 1.2 1.6 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase Peptidase_M7 PF02031.11 EAU80259.2 - 0.18 11.4 2.3 0.25 11.0 0.9 2.0 1 1 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family PBP PF01161.15 EAU80267.2 - 8.9e-19 67.7 1.7 1.8e-18 66.8 1.2 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein GAS PF13851.1 EAU80267.2 - 0.027 13.6 4.9 0.038 13.1 3.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF465 PF04325.8 EAU80267.2 - 0.098 12.3 0.1 0.098 12.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Bap31 PF05529.7 EAU80267.2 - 3.8 6.9 5.3 6 6.2 3.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like FYVE PF01363.16 EAU80269.1 - 3.3e-18 65.3 2.3 7.1e-18 64.2 1.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EAU80269.1 - 0.031 14.1 4.2 0.16 11.8 0.9 2.7 3 0 0 3 3 3 0 IBR domain zf-B_box PF00643.19 EAU80269.1 - 0.59 10.0 5.6 7 6.6 0.8 2.4 2 0 0 2 2 2 0 B-box zinc finger GAS PF13851.1 EAU80272.2 - 0.00053 19.2 10.8 0.00086 18.5 7.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Sec8_exocyst PF04048.9 EAU80272.2 - 0.0011 18.6 2.5 0.0023 17.5 1.7 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain EzrA PF06160.7 EAU80272.2 - 0.0012 17.1 2.4 0.0017 16.6 1.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Laminin_II PF06009.7 EAU80272.2 - 0.0035 17.0 5.0 0.0088 15.7 3.5 1.6 1 0 0 1 1 1 1 Laminin Domain II Atg14 PF10186.4 EAU80272.2 - 0.0079 15.1 1.8 0.014 14.3 1.3 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EAU80272.2 - 0.017 13.0 1.0 0.024 12.4 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.8 EAU80272.2 - 0.017 15.8 3.4 0.052 14.2 2.3 1.8 1 0 0 1 1 1 0 Occludin homology domain DUF972 PF06156.8 EAU80272.2 - 0.048 14.0 6.4 0.33 11.3 4.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) ZYG-11_interact PF05884.7 EAU80272.2 - 0.07 12.2 0.9 0.11 11.6 0.6 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF342 PF03961.8 EAU80272.2 - 0.089 11.1 3.6 0.15 10.4 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EAU80272.2 - 0.11 12.1 5.1 0.29 10.7 3.6 1.6 1 0 0 1 1 1 0 Mnd1 family APG6 PF04111.7 EAU80272.2 - 0.14 11.1 4.1 0.23 10.4 2.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 EAU80272.2 - 0.15 10.4 0.5 0.2 10.0 0.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2458 PF10454.4 EAU80272.2 - 0.16 11.8 6.4 0.35 10.7 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) PspA_IM30 PF04012.7 EAU80272.2 - 0.17 11.2 8.4 0.34 10.2 5.8 1.4 1 0 0 1 1 1 0 PspA/IM30 family IncA PF04156.9 EAU80272.2 - 0.31 10.6 9.0 0.52 9.8 6.3 1.3 1 0 0 1 1 1 0 IncA protein DUF3508 PF12018.3 EAU80272.2 - 0.31 9.9 5.8 0.054 12.4 0.8 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3508) DivIVA PF05103.8 EAU80272.2 - 0.31 11.0 7.1 1.5 8.8 4.6 2.2 1 1 0 1 1 1 0 DivIVA protein DUF2968 PF11180.3 EAU80272.2 - 0.36 10.1 6.8 0.67 9.3 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ADIP PF11559.3 EAU80272.2 - 0.5 10.2 11.6 1.3 8.9 8.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EAU80272.2 - 0.61 10.2 4.5 1.7 8.7 3.1 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.8 EAU80272.2 - 0.74 8.8 7.7 0.26 10.3 2.4 1.9 2 0 0 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.17 EAU80272.2 - 1.7 8.7 9.8 0.64 10.0 2.6 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EAU80272.2 - 8.6 5.9 10.1 7.8 6.0 1.4 2.4 1 1 1 2 2 2 0 Septum formation initiator Asp_protease_2 PF13650.1 EAU80276.1 - 0.00016 22.1 0.3 0.00057 20.3 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 EAU80276.1 - 0.0015 18.3 0.9 0.0029 17.4 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle PBCV_basic_adap PF08789.5 EAU80276.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 PBCV-specific basic adaptor domain zf-Di19 PF05605.7 EAU80279.2 - 0.0054 16.8 0.3 0.0076 16.3 0.2 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.20 EAU80281.1 - 4.8e-06 25.9 0.0 1.1e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80281.1 - 0.043 12.8 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU80282.2 - 1.9e-07 30.5 0.0 3.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80282.2 - 0.15 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Cauli_AT PF03233.8 EAU80283.2 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Aphid transmission protein NUP50 PF08911.6 EAU80283.2 - 0.012 15.9 0.1 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) NPV_P10 PF05531.7 EAU80287.2 - 0.01 16.0 1.5 0.025 14.8 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EAU80287.2 - 0.025 14.4 1.6 0.025 14.4 1.1 4.0 3 2 0 3 3 3 0 Tropomyosin like DUF1664 PF07889.7 EAU80287.2 - 1.5 8.6 5.6 0.59 9.9 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Lipoprotein_7 PF01540.11 EAU80287.2 - 1.8 7.5 9.5 4 6.4 6.6 1.5 1 1 0 1 1 1 0 Adhesin lipoprotein Prefoldin PF02996.12 EAU80287.2 - 3.7 7.2 9.8 2.9 7.5 0.4 3.8 2 1 1 3 3 3 0 Prefoldin subunit Laminin_II PF06009.7 EAU80287.2 - 6.2 6.5 15.7 0.15 11.7 2.0 3.1 3 1 0 3 3 3 0 Laminin Domain II TBPIP PF07106.8 EAU80287.2 - 7.7 6.0 15.1 0.6 9.6 0.6 3.3 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PDDEXK_2 PF12784.2 EAU80287.2 - 7.7 5.6 8.4 3.5 6.7 3.9 1.8 1 1 1 2 2 2 0 PD-(D/E)XK nuclease family transposase AAA_13 PF13166.1 EAU80287.2 - 8.2 4.7 11.7 17 3.7 8.1 1.6 1 1 0 1 1 1 0 AAA domain F-box PF00646.28 EAU80288.2 - 0.032 13.8 0.1 0.071 12.7 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EAU80288.2 - 0.045 13.4 0.1 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like ICMT PF04140.9 EAU80289.1 - 6.6e-13 48.6 1.7 5e-12 45.8 0.2 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EAU80289.1 - 6e-10 39.1 2.9 6.4e-09 35.8 0.5 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EAU80289.1 - 0.015 13.8 0.1 0.021 13.3 0.1 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family PTR2 PF00854.16 EAU80290.1 - 1.4e-44 152.4 5.1 2.2e-43 148.4 3.5 2.2 1 1 0 1 1 1 1 POT family CcmH PF03918.9 EAU80290.1 - 0.53 9.2 0.0 0.53 9.2 0.0 3.1 3 1 1 4 4 4 0 Cytochrome C biogenesis protein zf-MYND PF01753.13 EAU80291.2 - 1e-09 38.1 9.2 1.7e-09 37.3 6.4 1.4 1 0 0 1 1 1 1 MYND finger HATPase_c PF02518.21 EAU80294.2 - 1.3e-28 98.9 0.9 4.6e-28 97.1 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EAU80294.2 - 1.4e-23 83.0 0.2 5.6e-23 81.0 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HAMP PF00672.20 EAU80294.2 - 6.2e-21 74.3 10.4 3.1e-07 30.4 0.3 4.5 4 1 1 5 5 5 3 HAMP domain HisKA PF00512.20 EAU80294.2 - 8.2e-18 64.1 1.0 3.3e-17 62.2 0.7 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain F-box-like PF12937.2 EAU80295.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like DsbD PF02683.10 EAU80296.1 - 0.067 12.7 2.9 0.071 12.6 0.8 1.9 2 1 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region Peptidase_M43 PF05572.8 EAU80298.2 - 4e-09 36.2 0.0 6.6e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU80298.2 - 1.7e-06 28.1 0.1 2.9e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU80298.2 - 0.00014 22.4 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU80298.2 - 0.0044 17.0 0.4 0.0072 16.3 0.3 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU80298.2 - 0.0083 15.8 0.1 0.0096 15.6 0.1 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 EAU80298.2 - 0.0085 15.6 0.4 0.05 13.1 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EAU80298.2 - 0.018 13.9 1.1 0.028 13.2 0.2 1.7 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M57 PF12388.3 EAU80298.2 - 0.099 11.9 1.2 5.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase Porin_4 PF13609.1 EAU80298.2 - 4.8 6.6 12.1 23 4.3 8.4 1.9 1 1 0 1 1 1 0 Gram-negative porin GntP_permease PF02447.11 EAU80301.2 - 0.028 12.9 0.1 0.029 12.8 0.1 1.0 1 0 0 1 1 1 0 GntP family permease F-box-like PF12937.2 EAU80302.2 - 1.5e-07 31.0 4.6 3.7e-07 29.7 0.9 2.4 2 0 0 2 2 2 2 F-box-like Preseq_ALAS PF09029.5 EAU80303.2 - 0.029 14.3 0.7 0.085 12.8 0.5 1.8 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Glyco_hydro_61 PF03443.9 EAU80304.1 - 7.1e-43 146.9 0.0 9.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MA-Mit PF09245.5 EAU80305.2 - 0.15 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen EMP70 PF02990.11 EAU80306.2 - 0.049 12.0 2.3 0.061 11.7 1.6 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 YrhK PF14145.1 EAU80306.2 - 0.36 10.5 4.1 0.3 10.7 1.3 2.0 2 0 0 2 2 2 0 YrhK-like protein Ferritin_2 PF13668.1 EAU80307.1 - 1e-36 125.9 0.0 1.4e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 EAU80308.1 - 5.9e-35 120.1 0.1 9.1e-35 119.5 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain G-alpha PF00503.15 EAU80314.1 - 9.7e-124 412.9 0.0 1.1e-123 412.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU80314.1 - 1.9e-11 43.4 0.0 1.8e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_22 PF13401.1 EAU80314.1 - 0.0029 17.7 0.2 0.028 14.5 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EAU80314.1 - 0.0039 16.6 0.1 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DAP3 PF10236.4 EAU80314.1 - 0.0095 14.8 0.1 0.33 9.8 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 EAU80314.1 - 0.024 14.9 0.0 0.11 12.7 0.0 2.2 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EAU80314.1 - 0.026 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF815 PF05673.8 EAU80314.1 - 0.037 12.9 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 EAU80314.1 - 0.051 13.0 0.0 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF3832 PF12909.2 EAU80344.1 - 0.55 10.3 3.7 1.7 8.7 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3832) MscS_porin PF12795.2 EAU80346.2 - 0.058 12.6 2.0 0.068 12.4 0.3 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF1090 PF06476.7 EAU80346.2 - 0.063 12.9 0.2 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) COG2 PF06148.6 EAU80346.2 - 0.068 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sugarporin_N PF11471.3 EAU80346.2 - 0.071 12.7 0.2 0.071 12.7 0.2 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension FlgN PF05130.7 EAU80348.1 - 0.02 15.1 0.1 0.026 14.7 0.1 1.2 1 0 0 1 1 1 0 FlgN protein WGG PF10273.4 EAU80348.1 - 0.092 12.8 0.2 0.37 10.9 0.2 2.0 1 1 0 1 1 1 0 Pre-rRNA-processing protein TSR2 zf-RVT PF13966.1 EAU80349.2 - 0.0015 18.8 1.4 0.0043 17.3 0.9 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Baculo_PEP_C PF04513.7 EAU80350.2 - 0.87 9.4 5.6 0.21 11.4 0.6 2.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCD PF07860.6 EAU80351.2 - 0.023 14.1 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 WisP family C-Terminal Region Reprolysin_4 PF13583.1 EAU80352.2 - 0.036 13.5 0.6 0.079 12.4 0.4 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1189 PF06691.6 EAU80352.2 - 0.97 8.6 0.0 1.5 8.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) SNF2_N PF00176.18 EAU80360.1 - 3e-24 85.3 0.0 5.8e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU80360.1 - 3.1e-15 55.8 0.1 7.1e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_4 PF13871.1 EAU80360.1 - 0.0045 16.4 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 Helicase_C-like Mucin PF01456.12 EAU80363.2 - 2.6 7.7 11.4 0.18 11.5 2.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DPBB_1 PF03330.13 EAU80365.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel TTSSLRR PF12468.3 EAU80366.2 - 0.0056 16.1 0.3 0.021 14.3 0.2 2.0 1 0 0 1 1 1 1 Type III secretion system leucine rich repeat protein IncA PF04156.9 EAU80370.2 - 0.042 13.4 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 IncA protein Rota_NSP4 PF01452.11 EAU80371.2 - 0.051 12.9 0.4 0.079 12.2 0.2 1.3 1 1 0 1 1 1 0 Rotavirus non structural protein End3 PF12761.2 EAU80374.1 - 0.018 14.7 3.9 0.023 14.3 1.0 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Syntaxin-6_N PF09177.6 EAU80374.1 - 0.11 12.9 2.2 5.7 7.4 0.2 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal STAT1_TAZ2bind PF12162.3 EAU80374.1 - 0.13 11.7 0.2 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Sugarporin_N PF11471.3 EAU80376.2 - 0.01 15.4 0.4 0.031 13.9 0.3 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Zn_clus PF00172.13 EAU80376.2 - 1.6 8.7 8.0 1.4 8.9 0.5 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.2 EAU80378.2 - 4.2e-05 22.9 0.0 6.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF2310 PF10071.4 EAU80383.2 - 0.13 11.2 0.1 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Zn_Tnp_IS1595 PF12760.2 EAU80383.2 - 0.51 10.1 8.6 0.92 9.3 6.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EAU80383.2 - 0.56 10.1 3.2 4.2 7.4 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain YhfH PF14149.1 EAU80383.2 - 1.2 9.0 4.8 2.3 8.0 3.4 1.5 1 0 0 1 1 1 0 YhfH-like protein zf-CCHC PF00098.18 EAU80383.2 - 3.2 7.8 7.7 0.37 10.8 1.2 2.4 2 0 0 2 2 2 0 Zinc knuckle NICE-3 PF07406.6 EAU80385.2 - 0.039 13.4 0.1 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 NICE-3 protein IncA PF04156.9 EAU80386.2 - 0.06 12.9 5.2 0.13 11.8 3.6 1.6 1 0 0 1 1 1 0 IncA protein Sirohm_synth_C PF14823.1 EAU80386.2 - 0.085 12.1 0.3 0.2 11.0 0.2 1.6 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal KxDL PF10241.4 EAU80386.2 - 0.12 12.2 1.8 0.29 11.0 1.3 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein AAA_13 PF13166.1 EAU80386.2 - 0.14 10.6 2.6 0.23 9.8 1.8 1.3 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.8 EAU80386.2 - 0.77 8.7 2.7 1.4 7.9 1.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 EAU80386.2 - 1.5 6.5 2.2 2.5 5.8 1.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EAU80386.2 - 7.1 6.7 9.5 2 8.5 3.2 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family LRR_8 PF13855.1 EAU80388.2 - 0.0077 15.9 0.2 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat Helitron_like_N PF14214.1 EAU80393.2 - 4.9e-11 42.6 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Ran-binding PF05508.6 EAU80397.1 - 0.0028 16.6 0.7 0.0035 16.2 0.5 1.1 1 0 0 1 1 1 1 RanGTP-binding protein PLU-1 PF08429.6 EAU80397.1 - 0.0089 14.9 0.1 0.01 14.7 0.1 1.2 1 0 0 1 1 1 1 PLU-1-like protein Uso1_p115_C PF04871.8 EAU80397.1 - 0.069 13.0 1.3 0.087 12.7 0.9 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-CCHC PF00098.18 EAU80402.2 - 0.00011 21.8 1.7 0.00023 20.9 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EAU80402.2 - 0.0098 15.3 0.8 0.02 14.3 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 EAU80413.2 - 4.2e-08 32.7 0.5 9.4e-08 31.6 0.0 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EAU80413.2 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EAU80413.2 - 2.6e-05 23.5 0.4 5.4e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Neur_chan_memb PF02932.11 EAU80413.2 - 0.096 12.5 3.2 0.18 11.6 2.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-BED PF02892.10 EAU80422.2 - 0.00049 19.7 1.7 0.00098 18.8 1.2 1.5 1 0 0 1 1 1 1 BED zinc finger HTH_Tnp_Tc5 PF03221.11 EAU80422.2 - 0.044 13.5 0.0 0.42 10.4 0.0 2.4 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain DUF1143 PF06608.6 EAU80425.2 - 0.13 12.3 0.6 0.21 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) DNApol3-delta_C PF09115.5 EAU80427.2 - 0.21 11.6 1.6 0.38 10.7 0.4 1.9 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal DUF846 PF05832.7 EAU80430.2 - 0.049 13.3 0.7 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) DUF2945 PF11160.3 EAU80431.2 - 0.078 12.8 0.5 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2945) LRV_FeS PF05484.6 EAU80436.2 - 0.077 12.5 0.0 92 2.7 0.0 3.3 3 0 0 3 3 3 0 LRV protein FeS4 cluster DUF1183 PF06682.7 EAU80436.2 - 6.7 6.2 12.5 11 5.5 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1688 PF07958.6 EAU80439.1 - 9.4e-162 538.3 0.0 1.1e-161 538.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.1 EAU80440.1 - 7.3e-12 44.4 16.3 7.3e-12 44.4 11.3 3.1 3 1 0 3 3 3 1 MFS/sugar transport protein tRNA-synt_2b PF00587.20 EAU80442.2 - 1.5e-43 148.3 0.4 2.8e-43 147.5 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAU80442.2 - 1e-17 63.8 0.2 1e-16 60.6 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.16 EAU80442.2 - 1e-14 54.0 0.0 1.3e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 EAU80442.2 - 1e-12 47.6 0.0 2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain AAA_17 PF13207.1 EAU80443.2 - 2e-05 25.4 0.0 3.2e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU80443.2 - 2.4e-05 24.6 0.1 7.6e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EAU80443.2 - 0.0073 15.9 0.1 0.024 14.2 0.1 1.9 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 EAU80443.2 - 0.012 15.1 0.2 0.15 11.5 0.2 2.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EAU80443.2 - 0.032 14.1 0.0 0.076 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU80443.2 - 0.033 14.0 0.0 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain T2SE PF00437.15 EAU80443.2 - 0.082 11.7 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Spo7 PF03907.8 EAU80444.2 - 2.5e-14 53.3 9.6 2.2e-13 50.3 1.1 2.7 2 1 0 2 2 2 2 Spo7-like protein Tmemb_18A PF09771.4 EAU80444.2 - 0.17 11.8 1.0 0.44 10.5 0.7 1.6 1 1 0 1 1 1 0 Transmembrane protein 188 DUF805 PF05656.9 EAU80444.2 - 0.76 9.6 3.1 2.1 8.1 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) AA_permease PF00324.16 EAU80445.2 - 0.026 12.8 5.3 0.03 12.6 3.7 1.1 1 0 0 1 1 1 0 Amino acid permease DUF1003 PF06210.6 EAU80445.2 - 0.053 13.4 0.7 0.08 12.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Polysacc_synt_3 PF13440.1 EAU80445.2 - 0.15 11.5 8.4 0.42 10.0 1.3 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein SEO_N PF14576.1 EAU80445.2 - 0.16 11.2 0.1 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Sieve element occlusion N-terminus Adeno_E3B PF03376.9 EAU80445.2 - 0.59 10.0 3.9 0.14 12.0 0.3 1.7 2 0 0 2 2 2 0 Adenovirus E3B protein DUF4191 PF13829.1 EAU80445.2 - 0.98 8.4 6.4 0.34 9.9 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) DUF4131 PF13567.1 EAU80445.2 - 1.3 8.3 3.7 0.77 9.1 0.8 1.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Asp PF00026.18 EAU80448.2 - 4e-22 78.8 0.0 2.2e-20 73.1 0.0 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EAU80448.2 - 0.024 15.1 0.2 0.39 11.2 0.1 2.6 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.1 EAU80448.2 - 0.042 13.3 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal CAS_CSE1 PF03378.10 EAU80449.1 - 2.4e-111 372.1 0.0 4.4e-111 371.2 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EAU80449.1 - 2.6e-105 352.0 0.0 5.3e-105 351.0 0.0 1.5 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 EAU80449.1 - 5.4e-14 51.8 0.0 5.2e-13 48.7 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EAU80449.1 - 2.7e-05 24.3 1.1 3.8 7.8 0.2 4.8 3 2 1 5 5 5 2 HEAT repeats Xpo1 PF08389.7 EAU80449.1 - 0.013 15.4 0.1 0.073 12.9 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein WD40 PF00400.27 EAU80450.1 - 2e-25 87.6 16.4 1.7e-08 34.0 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EAU80450.1 - 0.0001 22.0 0.0 0.01 15.5 0.0 3.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Sec10 PF07393.6 EAU80452.2 - 2.5e-131 439.2 0.0 2.9e-131 438.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.28 EAU80452.2 - 0.0034 17.0 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Lipoprotein_20 PF13942.1 EAU80453.1 - 0.04 13.4 0.3 0.04 13.4 0.2 1.5 2 0 0 2 2 2 0 YfhG lipoprotein DUF2383 PF09537.5 EAU80453.1 - 0.066 13.4 1.9 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) YscO PF07321.7 EAU80453.1 - 1 9.1 13.4 11 5.7 9.3 2.0 1 1 0 1 1 1 0 Type III secretion protein YscO OmpH PF03938.9 EAU80453.1 - 1.9 8.4 5.4 4.1 7.3 3.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 EAU80453.1 - 8.7 6.7 14.0 1.6 9.0 1.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Tet_JBP PF12851.2 EAU80456.2 - 1.4e-12 47.2 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily BCL_N PF04714.8 EAU80457.1 - 1.1 8.8 4.2 1.1 8.8 1.6 1.9 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Sugarporin_N PF11471.3 EAU80460.2 - 0.0048 16.5 0.4 0.0098 15.5 0.3 1.5 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Zn_clus PF00172.13 EAU80460.2 - 0.05 13.5 4.6 0.34 10.8 0.1 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain STAT1_TAZ2bind PF12162.3 EAU80462.2 - 0.11 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain IF-2B PF01008.12 EAU80462.2 - 0.14 11.1 1.5 0.16 10.9 1.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF1672 PF07901.6 EAU80462.2 - 0.17 10.8 0.4 0.2 10.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) NPV_P10 PF05531.7 EAU80462.2 - 0.21 11.8 4.2 2.7 8.3 0.5 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 EAU80462.2 - 2.6 8.4 5.6 8.4 6.8 2.4 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4472 PF14739.1 EAU80464.2 - 0.074 13.5 0.6 0.9 10.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF2730 PF10805.3 EAU80464.2 - 0.092 12.4 0.8 1.7 8.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Cytochrom_C_2 PF01322.15 EAU80465.2 - 0.023 15.2 0.0 0.069 13.6 0.0 1.7 2 0 0 2 2 2 0 Cytochrome C' NICE-3 PF07406.6 EAU80467.2 - 0.039 13.4 0.1 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 NICE-3 protein Sirohm_synth_C PF14823.1 EAU80468.2 - 0.079 12.2 0.3 0.16 11.2 0.2 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal IncA PF04156.9 EAU80468.2 - 0.081 12.5 5.7 0.14 11.7 3.9 1.4 1 0 0 1 1 1 0 IncA protein KxDL PF10241.4 EAU80468.2 - 0.13 12.2 2.1 0.3 11.0 1.5 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein AAA_13 PF13166.1 EAU80468.2 - 0.15 10.5 2.9 0.23 9.8 2.0 1.3 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.8 EAU80468.2 - 0.62 9.0 2.5 1 8.3 1.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Cortex-I_coil PF09304.5 EAU80468.2 - 1.1 9.2 11.6 3.3 7.8 0.2 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil V_ATPase_I PF01496.14 EAU80468.2 - 1.6 6.4 2.5 2.5 5.8 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EAU80468.2 - 2 8.5 6.8 1.6 8.8 3.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EAU80468.2 - 6.3 5.3 9.8 12 4.4 6.4 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Med9 PF07544.8 EAU80468.2 - 8.1 6.2 11.3 0.45 10.2 2.5 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Dyp_perox PF04261.7 EAU80479.2 - 0.15 10.7 0.0 0.37 9.4 0.0 1.9 1 1 0 1 1 1 0 Dyp-type peroxidase family Med3 PF11593.3 EAU80481.1 - 0.0089 15.3 10.5 0.008 15.4 6.8 1.5 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal TMEM61 PF15105.1 EAU80481.1 - 0.055 13.0 0.1 0.055 13.0 0.1 2.2 2 0 0 2 2 2 0 TMEM61 protein family ORC6 PF05460.8 EAU80481.1 - 0.19 10.8 7.6 0.24 10.4 5.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) API5 PF05918.6 EAU80481.1 - 0.32 9.4 1.1 0.44 8.9 0.8 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Proteasome PF00227.21 EAU80485.1 - 4.4e-39 133.7 0.0 5.4e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit 4HBT PF03061.17 EAU80486.1 - 1.2e-08 34.9 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EAU80486.1 - 5.8e-07 29.9 0.0 7.1e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EAU80486.1 - 0.0042 16.0 0.6 0.0067 15.3 0.4 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase Ribosomal_60s PF00428.14 EAU80487.2 - 1.2e-26 92.8 11.5 5.4e-26 90.8 8.0 2.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Peptidase_C97 PF05903.9 EAU80489.2 - 0.0069 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EAU80489.2 - 0.0091 15.9 1.4 0.074 13.0 0.9 2.2 1 1 0 1 1 1 1 Lecithin retinol acyltransferase ETF_QO PF05187.8 EAU80495.2 - 2.5e-23 82.1 1.7 3.1e-15 56.1 0.2 3.3 2 1 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 EAU80495.2 - 9e-08 32.0 0.0 3.4e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU80495.2 - 1.1e-05 24.5 0.0 3.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAU80495.2 - 3.3e-05 23.8 0.0 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU80495.2 - 7.3e-05 21.7 0.6 7.3e-05 21.7 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EAU80495.2 - 9.1e-05 21.0 0.3 0.00014 20.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EAU80495.2 - 9.9e-05 22.4 0.0 0.00028 20.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU80495.2 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EAU80495.2 - 0.00025 20.2 0.2 0.0004 19.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EAU80495.2 - 0.00031 19.8 0.1 0.00081 18.5 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EAU80495.2 - 0.0015 17.6 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU80495.2 - 0.0016 17.4 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EAU80495.2 - 0.031 12.9 0.2 0.053 12.1 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 EAU80495.2 - 0.11 11.3 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A CTP_transf_1 PF01148.15 EAU80496.2 - 1.5e-12 47.6 5.4 8.3e-10 38.7 2.0 2.4 1 1 1 2 2 2 2 Cytidylyltransferase family Sensor PF13796.1 EAU80496.2 - 0.13 11.8 14.3 0.69 9.4 5.7 2.5 1 1 1 2 2 2 0 Putative sensor HhH-GPD PF00730.20 EAU80497.2 - 0.00021 21.5 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ribosomal_S17e PF00833.13 EAU80498.1 - 1.2e-57 192.9 0.1 1.4e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.14 EAU80499.1 - 5.3e-27 94.2 0.1 7.5e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 5_nucleotid_C PF02872.13 EAU80500.2 - 2.5e-24 86.0 0.0 4.8e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EAU80500.2 - 8.4e-10 38.3 0.1 1.7e-09 37.3 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU80500.2 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain LRR_4 PF12799.2 EAU80502.1 - 0.021 14.4 2.5 0.1 12.2 0.1 3.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) 4HBT PF03061.17 EAU80503.2 - 2.9e-06 27.3 0.1 3.8e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily Fer2 PF00111.22 EAU80504.2 - 1.8e-05 24.4 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PQ-loop PF04193.9 EAU80507.2 - 4.9e-12 45.2 7.9 1.3e-11 43.9 0.2 3.3 3 0 0 3 3 3 2 PQ loop repeat UPF0093 PF03653.8 EAU80507.2 - 0.56 10.1 9.6 0.71 9.8 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) DUF4191 PF13829.1 EAU80507.2 - 2.9 6.9 5.6 0.24 10.4 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) S-antigen PF05756.6 EAU80517.1 - 0.034 14.1 0.2 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 S-antigen protein Tet_JBP PF12851.2 EAU80519.2 - 1.4e-12 47.2 0.0 2.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Lipoprotein_20 PF13942.1 EAU80521.1 - 0.04 13.4 0.3 0.04 13.4 0.2 1.6 2 0 0 2 2 2 0 YfhG lipoprotein VSG_B PF13206.1 EAU80521.1 - 0.08 12.0 0.1 0.092 11.8 0.1 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF2383 PF09537.5 EAU80521.1 - 0.28 11.4 0.2 0.28 11.4 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) YscO PF07321.7 EAU80521.1 - 0.44 10.3 12.8 1.7 8.4 8.9 1.7 1 1 0 1 1 1 0 Type III secretion protein YscO OmpH PF03938.9 EAU80521.1 - 4.8 7.1 6.8 8.9 6.2 4.4 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 EAU80521.1 - 9.8 6.5 14.2 2 8.7 1.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) SDA1 PF05285.7 EAU80522.2 - 3 7.0 12.7 5 6.3 8.8 1.3 1 0 0 1 1 1 0 SDA1 Rota_NSP4 PF01452.11 EAU80527.2 - 0.051 12.9 0.4 0.079 12.2 0.2 1.3 1 1 0 1 1 1 0 Rotavirus non structural protein NYD-SP12_N PF15015.1 EAU80529.1 - 0.055 11.6 0.0 0.072 11.3 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal DDE_2 PF02914.10 EAU80532.2 - 0.0051 16.3 0.0 0.0087 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacteriophage Mu transposase Mak16 PF04874.9 EAU80533.2 - 0.13 12.3 4.7 0.19 11.8 3.3 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region PIF1 PF05970.9 EAU80534.2 - 3.2e-05 23.0 0.4 0.0012 17.8 0.1 2.7 3 0 0 3 3 3 1 PIF1-like helicase AAA_19 PF13245.1 EAU80534.2 - 0.00033 20.3 0.1 0.0027 17.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAU80534.2 - 0.0017 17.9 0.1 0.005 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain zf-CpG_bind_C PF12269.3 EAU80535.1 - 0.0097 15.4 1.6 0.014 14.9 1.1 1.2 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain DUF342 PF03961.8 EAU80535.1 - 0.021 13.2 2.1 0.024 13.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4201 PF13870.1 EAU80535.1 - 0.025 14.0 6.8 0.031 13.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF3829 PF12889.2 EAU80535.1 - 0.053 12.7 0.9 0.06 12.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) HlyE PF06109.8 EAU80535.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Haemolysin E (HlyE) Spc7 PF08317.6 EAU80535.1 - 0.067 11.8 5.1 0.078 11.6 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.7 EAU80535.1 - 0.15 11.9 2.3 0.33 10.7 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) SapB_1 PF05184.10 EAU80535.1 - 0.16 11.8 0.3 0.39 10.5 0.2 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 DUF4613 PF15390.1 EAU80535.1 - 0.21 9.7 2.2 0.24 9.5 1.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DivIVA PF05103.8 EAU80535.1 - 0.42 10.6 4.2 0.27 11.2 0.3 2.2 1 1 1 2 2 2 0 DivIVA protein YtxH PF12732.2 EAU80535.1 - 0.74 10.2 3.5 0.75 10.1 1.5 1.8 1 1 1 2 2 2 0 YtxH-like protein Atg14 PF10186.4 EAU80535.1 - 2.6 6.9 9.3 2.9 6.7 6.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADH_zinc_N_2 PF13602.1 EAU80537.2 - 0.032 15.1 0.3 0.2 12.5 0.2 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ATP_bind_3 PF01171.15 EAU80538.1 - 1e-18 67.4 0.1 2.1e-18 66.4 0.0 1.5 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 EAU80538.1 - 0.003 17.8 0.0 0.0071 16.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EAU80538.1 - 0.012 14.2 0.0 0.018 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.9 EAU80538.1 - 0.13 11.7 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Peptidase_S9_N PF02897.10 EAU80539.1 - 8.7e-86 288.0 6.9 1.2e-85 287.6 4.8 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EAU80539.1 - 6.4e-63 211.8 0.3 8.4e-62 208.1 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EAU80539.1 - 0.002 17.7 0.1 0.011 15.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold EAF PF09816.4 EAU80540.1 - 1.4e-14 54.0 1.2 1.5e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Ferritin_2 PF13668.1 EAU80541.1 - 1.5e-34 118.8 1.0 2.3e-34 118.2 0.7 1.3 1 0 0 1 1 1 1 Ferritin-like domain 2TM PF13239.1 EAU80542.2 - 2.5 8.2 4.7 1.1 9.4 0.1 2.4 3 0 0 3 3 3 0 2TM domain KH_1 PF00013.24 EAU80543.2 - 8.3e-06 25.3 0.0 2.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EAU80543.2 - 0.00063 19.3 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EAU80543.2 - 0.0051 16.4 0.0 0.017 14.7 0.0 1.9 1 0 0 1 1 1 1 KH domain SNF2_N PF00176.18 EAU80544.2 - 2.1e-55 187.6 0.1 1.7e-49 168.2 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU80544.2 - 2.4e-09 36.9 0.0 4.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EAU80544.2 - 1.9e-05 24.3 6.1 1.9e-05 24.3 4.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAU80544.2 - 2.6e-05 23.7 5.8 2.6e-05 23.7 4.0 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU80544.2 - 9e-05 22.4 4.7 9e-05 22.4 3.2 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EAU80544.2 - 0.00019 20.8 2.5 0.00045 19.6 1.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EAU80544.2 - 0.00042 20.3 1.1 0.0011 19.0 0.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EAU80544.2 - 0.0056 16.5 5.3 0.0056 16.5 3.7 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 EAU80544.2 - 0.0066 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 EAU80544.2 - 0.0084 15.7 3.9 0.0084 15.7 2.7 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAU80544.2 - 0.0093 15.7 1.0 0.024 14.4 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DEAD_2 PF06733.10 EAU80544.2 - 0.055 12.8 0.4 0.38 10.1 0.0 2.6 2 1 0 2 2 2 0 DEAD_2 zf-RING_6 PF14835.1 EAU80544.2 - 0.096 12.4 0.7 0.19 11.4 0.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EAU80544.2 - 0.45 10.2 3.9 1.5 8.5 2.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Dicty_REP PF05086.7 EAU80544.2 - 9.6 3.8 6.1 15 3.2 4.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acyl-CoA_dh_1 PF00441.19 EAU80545.1 - 1.5e-24 86.7 0.4 2.3e-24 86.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAU80545.1 - 1.1e-19 69.7 1.8 2.9e-19 68.3 1.3 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EAU80545.1 - 4.7e-16 58.3 0.1 2e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EAU80545.1 - 2.5e-12 47.3 0.0 8.7e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain RRM_3 PF08777.6 EAU80548.1 - 7.1e-06 25.8 0.0 0.0063 16.3 0.0 2.7 2 1 0 2 2 2 2 RNA binding motif RRM_6 PF14259.1 EAU80548.1 - 0.00013 21.9 0.0 0.0056 16.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU80548.1 - 0.0024 17.4 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU80548.1 - 0.078 12.8 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box PF00646.28 EAU80551.1 - 6.1e-06 25.7 0.6 2.1e-05 24.0 0.4 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU80551.1 - 5.4e-05 22.8 0.4 0.00014 21.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like Glyco_hydro_61 PF03443.9 EAU80552.2 - 1.3e-45 155.9 0.0 1.7e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DnaJ_CXXCXGXG PF00684.14 EAU80553.2 - 0.0002 21.3 5.3 0.12 12.4 0.4 2.5 2 0 0 2 2 2 2 DnaJ central domain Cytochrome_C7 PF14522.1 EAU80553.2 - 0.064 12.8 1.0 4.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 EAU80553.2 - 0.096 13.0 0.4 6.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c3 SH3_1 PF00018.23 EAU80555.2 - 1.9e-15 55.9 0.1 3.1e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU80555.2 - 1.1e-14 53.7 0.2 1.7e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU80555.2 - 8.2e-13 47.6 0.0 1.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Metal_resist PF13801.1 EAU80555.2 - 4.3 7.3 7.1 2.5 8.0 0.7 2.9 2 1 0 2 2 2 0 Heavy-metal resistance Mito_fiss_reg PF05308.6 EAU80555.2 - 7.4 5.8 8.8 13 5.0 6.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_L2_C PF03947.13 EAU80558.1 - 3.9e-42 143.1 2.4 5.8e-42 142.5 1.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EAU80558.1 - 3.1e-15 55.8 0.1 7.2e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Response_reg PF00072.19 EAU80559.1 - 4.5e-22 78.1 0.2 3.9e-16 59.0 0.1 2.4 2 0 0 2 2 2 2 Response regulator receiver domain DUF3546 PF12066.3 EAU80560.1 - 2.9e-16 59.4 1.5 8.3e-16 57.9 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EAU80560.1 - 3e-11 43.9 3.3 3e-11 43.9 2.3 2.9 3 1 0 3 3 3 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EAU80560.1 - 8.1e-06 25.3 2.8 8.8e-06 25.2 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 EAU80560.1 - 0.014 15.5 2.6 0.44 10.6 0.1 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RRM_1 PF00076.17 EAU80560.1 - 0.016 14.7 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-BED PF02892.10 EAU80560.1 - 0.037 13.8 0.1 0.094 12.4 0.1 1.7 1 0 0 1 1 1 0 BED zinc finger CaM_binding PF07839.6 EAU80560.1 - 0.069 13.3 0.2 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Plant calmodulin-binding domain zf-met2 PF12907.2 EAU80560.1 - 0.096 12.6 1.9 0.19 11.7 1.3 1.5 1 0 0 1 1 1 0 Zinc-binding zf-C2H2 PF00096.21 EAU80560.1 - 4.6 7.7 6.3 0.4 11.1 0.9 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRM_6 PF14259.1 EAU80561.1 - 1.4e-07 31.4 0.0 5.6e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU80561.1 - 0.00022 20.8 0.0 0.035 13.7 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU80561.1 - 0.0093 15.7 0.0 0.047 13.5 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_6 PF13516.1 EAU80563.2 - 0.021 14.8 2.8 2.5 8.4 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Amidoligase_2 PF12224.3 EAU80563.2 - 0.036 13.6 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative amidoligase enzyme LRR_4 PF12799.2 EAU80563.2 - 0.98 9.1 6.5 0.18 11.4 0.2 2.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) ERG2_Sigma1R PF04622.7 EAU80564.2 - 2.2e-91 304.9 1.2 2.6e-91 304.7 0.8 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3950 PF13132.1 EAU80564.2 - 0.066 12.7 1.0 0.12 11.9 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) UAA PF08449.6 EAU80565.2 - 1.5e-58 198.1 9.4 1.6e-25 89.6 0.3 3.8 2 1 0 3 3 3 3 UAA transporter family Cyclin PF08613.6 EAU80566.2 - 1.4e-13 51.4 0.4 6.3e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EAU80566.2 - 1.1e-09 37.8 0.0 1.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain F-box-like PF12937.2 EAU80567.2 - 2.2e-05 24.0 0.0 4.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like RCC1 PF00415.13 EAU80568.1 - 9.4e-18 64.1 8.7 0.00041 20.4 0.2 7.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAU80568.1 - 2e-09 36.8 15.2 1.2e-05 24.8 0.1 6.0 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat NmrA PF05368.8 EAU80569.1 - 8.3e-28 97.2 0.0 9.4e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAU80569.1 - 6.3e-06 26.3 0.0 9.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAU80569.1 - 0.031 13.7 0.0 0.071 12.5 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MIF4G_like PF09088.6 EAU80570.1 - 8.6e-60 201.4 0.1 2.2e-59 200.1 0.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EAU80570.1 - 7.7e-38 130.1 0.0 1.2e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EAU80570.1 - 0.0017 17.8 0.0 0.033 13.5 0.0 2.3 2 0 0 2 2 2 1 MIF4G domain PPR_3 PF13812.1 EAU80571.2 - 3.5e-06 26.8 0.8 0.59 10.5 0.1 4.7 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EAU80571.2 - 0.0049 16.8 0.0 10 6.1 0.0 3.8 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.15 EAU80571.2 - 0.049 13.6 0.1 83 3.4 0.0 3.8 3 0 0 3 3 3 0 PPR repeat TPR_16 PF13432.1 EAU80571.2 - 0.13 12.9 6.0 6.1 7.6 0.0 4.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAU80571.2 - 1.8 9.3 7.1 37 5.3 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat IF3_C PF00707.17 EAU80572.1 - 9.1e-05 22.1 0.6 9.1e-05 22.1 0.4 2.1 1 1 1 2 2 2 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.11 EAU80572.1 - 0.032 14.1 0.0 0.097 12.6 0.0 1.9 1 1 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain YbaB_DNA_bd PF02575.11 EAU80572.1 - 0.05 13.5 2.2 0.14 12.0 1.5 1.7 1 1 0 1 1 1 0 YbaB/EbfC DNA-binding family adh_short PF00106.20 EAU80573.1 - 0.0013 18.6 0.1 1.4 8.7 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase EMG1 PF03587.9 EAU80576.2 - 3.7e-24 85.1 0.0 1.9e-12 46.9 0.0 2.0 2 0 0 2 2 2 2 EMG1/NEP1 methyltransferase CRAL_TRIO PF00650.15 EAU80577.1 - 2.2e-36 124.7 0.0 3.4e-36 124.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAU80577.1 - 3.5e-10 39.8 1.3 3.5e-10 39.8 0.9 2.4 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EAU80577.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Porphobil_deam PF01379.15 EAU80578.1 - 6.5e-75 250.7 0.0 9.5e-75 250.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EAU80578.1 - 2.5e-20 72.3 0.6 4.7e-20 71.4 0.4 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Profilin PF00235.14 EAU80578.1 - 0.086 12.9 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Profilin DUF2638 PF10937.3 EAU80579.1 - 6e-10 40.1 3.2 2.1e-08 35.1 2.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) AF-4 PF05110.8 EAU80579.1 - 6.6 4.4 10.0 8.1 4.1 6.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.4 EAU80579.1 - 7.5 5.9 7.5 9.9 5.5 5.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Proteasome PF00227.21 EAU80580.1 - 5.9e-44 149.6 0.0 2.5e-43 147.5 0.0 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAU80580.1 - 3.4e-15 55.0 0.4 6.2e-15 54.2 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb1_5 PF04998.12 EAU80581.1 - 4.1e-92 308.3 0.0 6e-92 307.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EAU80581.1 - 3.1e-87 293.0 0.0 4.3e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EAU80581.1 - 1.5e-68 229.9 0.0 3.1e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EAU80581.1 - 4.8e-38 130.3 0.0 3.8e-36 124.2 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EAU80581.1 - 7.2e-33 112.5 0.0 1.6e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 EAU80581.1 - 0.025 14.0 0.0 0.069 12.6 0.0 1.8 1 0 0 1 1 1 0 InsA N-terminal domain ArdA PF07275.6 EAU80582.1 - 0.61 10.3 1.5 1 9.5 1.1 1.3 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Glyco_hydro_63 PF03200.11 EAU80582.1 - 7.3 4.2 11.8 13 3.4 8.2 1.3 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase HTH_1 PF00126.22 EAU80583.2 - 0.059 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family S4 PF01479.20 EAU80584.2 - 2.3e-10 39.7 0.0 4e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EAU80584.2 - 2.3e-09 37.5 0.2 4.4e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain LIM_bind PF01803.11 EAU80585.2 - 6.2e-71 238.2 0.0 6.2e-71 238.2 0.0 2.2 3 0 0 3 3 3 1 LIM-domain binding protein Kinesin PF00225.18 EAU80586.2 - 1.7e-86 290.0 0.0 2.6e-86 289.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EAU80586.2 - 4.5e-41 139.7 0.0 1e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EAU80586.2 - 9.8e-11 41.7 0.0 4.9e-10 39.5 0.0 2.2 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 EAU80586.2 - 3e-07 30.3 0.8 8.7e-07 28.8 0.5 1.9 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EAU80586.2 - 3.4e-06 27.0 0.0 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 FHA domain CMAS PF02353.15 EAU80587.1 - 7.5e-55 185.9 0.0 1e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EAU80587.1 - 9.6e-07 28.6 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU80587.1 - 1.9e-06 28.4 0.0 3.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU80587.1 - 2.4e-05 24.7 0.0 5.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU80587.1 - 0.0082 16.1 0.0 0.02 14.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU80587.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU80587.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SAC3 PF12209.3 EAU80587.1 - 0.065 13.3 0.5 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain Methyltransf_12 PF08242.7 EAU80587.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Lipase_3 PF01764.20 EAU80594.2 - 0.00016 21.2 0.0 0.047 13.3 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) Peptidase_M24 PF00557.19 EAU80595.2 - 4.4e-53 179.9 0.1 6e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EAU80595.2 - 5.9e-24 83.9 0.0 2.1e-23 82.1 0.0 1.9 2 1 0 2 2 2 1 Aminopeptidase P, N-terminal domain Nop PF01798.13 EAU80596.1 - 2.1e-59 199.0 0.8 2.1e-59 199.0 0.6 2.4 3 0 0 3 3 3 1 Putative snoRNA binding domain NOSIC PF08060.8 EAU80596.1 - 1.3e-26 92.1 0.3 2.3e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EAU80596.1 - 2.2e-19 69.3 0.1 2.2e-19 69.3 0.1 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain F-box-like PF12937.2 EAU80597.1 - 6.5e-06 25.7 0.3 2.3e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAU80597.1 - 3.6 7.3 8.9 0.95 9.1 0.1 4.0 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Med26 PF08711.6 EAU80599.2 - 8.9e-09 34.7 0.0 1.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CSTF2_hinge PF14327.1 EAU80599.2 - 0.092 12.8 1.3 0.28 11.3 0.1 2.5 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 HMG_box PF00505.14 EAU80600.1 - 6.5e-20 71.1 3.2 1.4e-19 70.0 2.2 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU80600.1 - 2e-15 56.8 3.1 7.3e-15 55.0 2.2 2.0 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EAU80600.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Na_trans_assoc PF06512.8 EAU80600.1 - 0.58 10.0 21.6 0.61 10.0 14.6 1.3 1 1 0 1 1 1 0 Sodium ion transport-associated WW PF00397.21 EAU80601.1 - 0.052 13.4 1.4 0.052 13.4 1.0 2.6 2 0 0 2 2 2 0 WW domain F-box-like PF12937.2 EAU80602.2 - 5.6e-08 32.3 1.7 2.1e-06 27.3 0.0 2.7 3 0 0 3 3 3 2 F-box-like LRR_8 PF13855.1 EAU80602.2 - 2.8 7.7 9.7 1.3 8.7 0.0 4.0 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EAU80603.1 - 0.00025 20.6 0.0 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like HlyC PF02794.11 EAU80608.2 - 0.026 14.1 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 RTX toxin acyltransferase family Hydrophobin PF01185.13 EAU80609.1 - 7.5e-22 77.5 14.0 9.8e-22 77.2 9.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin E1-E2_ATPase PF00122.15 EAU80611.2 - 2.3e-13 49.7 0.0 2.3e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAU80611.2 - 2.9e-12 47.4 2.9 1.1e-06 29.2 0.5 3.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU80611.2 - 3e-12 47.0 0.1 2.6e-11 44.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAU80611.2 - 8.3e-12 44.9 0.0 2.4e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAU80611.2 - 3.8e-05 23.3 1.4 0.006 16.1 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAU80611.2 - 0.019 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IncA PF04156.9 EAU80614.2 - 1.2e-05 24.9 0.4 2.2e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 IncA protein OmpH PF03938.9 EAU80614.2 - 0.012 15.5 2.6 0.02 14.8 1.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Herpes_gE PF02480.11 EAU80614.2 - 0.016 13.4 0.8 0.029 12.6 0.0 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EAU80614.2 - 0.15 10.8 0.0 0.33 9.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Transposase_22 PF02994.9 EAU80614.2 - 0.57 8.6 3.8 0.99 7.8 2.6 1.3 1 0 0 1 1 1 0 L1 transposable element YlqD PF11068.3 EAU80614.2 - 2.4 8.2 9.2 3.8 7.5 6.4 1.3 1 0 0 1 1 1 0 YlqD protein DUF4140 PF13600.1 EAU80614.2 - 7.9 6.9 9.7 59 4.1 0.2 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) WD40 PF00400.27 EAU80615.2 - 4.9e-05 23.0 3.2 0.11 12.4 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HALZ PF02183.13 EAU80615.2 - 0.099 12.3 1.0 0.23 11.2 0.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper UCH PF00443.24 EAU80616.2 - 6.8e-40 136.8 0.0 9.3e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EAU80616.2 - 1.2e-32 113.1 0.0 1.9e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 EAU80616.2 - 2.7e-18 66.4 0.0 4.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Inhibitor_I48 PF10467.4 EAU80616.2 - 0.081 12.8 0.0 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase inhibitor clitocypin DUF382 PF04037.8 EAU80617.2 - 6.8e-62 207.0 0.4 6.8e-62 207.0 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EAU80617.2 - 5.2e-19 67.3 6.6 9.9e-19 66.4 4.6 1.5 1 0 0 1 1 1 1 PSP Membralin PF09746.4 EAU80617.2 - 0.53 9.2 0.8 0.93 8.4 0.6 1.3 1 0 0 1 1 1 0 Tumour-associated protein BSP_II PF05432.6 EAU80617.2 - 0.55 9.4 17.2 2.2 7.4 2.8 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 EAU80617.2 - 2.2 7.9 13.5 5.4 6.6 1.6 2.6 2 0 0 2 2 2 0 FAM176 family MitMem_reg PF13012.1 EAU80618.2 - 8.8e-36 122.4 0.5 1.6e-35 121.6 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EAU80618.2 - 8.8e-28 96.3 0.0 2.3e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Hydrophobin PF01185.13 EAU80619.1 - 1.1e-21 77.1 14.2 1.4e-21 76.6 9.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EAU80621.1 - 9.3e-22 77.2 13.9 1.2e-21 76.9 9.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EAU80622.1 - 1.6e-17 63.6 11.7 2.2e-17 63.2 8.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.2 EAU80623.2 - 0.0001 21.9 0.2 0.00033 20.3 0.2 2.0 1 1 0 1 1 1 1 F-box-like Coa1 PF08695.5 EAU80624.1 - 3.4e-29 100.7 0.0 4.3e-28 97.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1469 PF07332.6 EAU80624.1 - 0.056 13.1 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Glyco_hydro_16 PF00722.16 EAU80625.1 - 8e-22 77.4 1.8 9.8e-22 77.1 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 EAU80625.1 - 1.9 7.7 13.7 3.5 6.9 9.5 1.3 1 0 0 1 1 1 0 Vta1 like Glyco_trans_2_3 PF13632.1 EAU80626.1 - 3.2e-53 180.3 0.2 3.2e-53 180.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAU80626.1 - 1.1e-11 45.0 0.1 5.5e-11 42.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAU80626.1 - 0.0013 18.4 0.0 0.011 15.3 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 2 ADH_zinc_N PF00107.21 EAU80627.1 - 6.3e-23 80.7 0.2 1e-22 80.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU80627.1 - 5e-09 37.1 0.1 1.1e-08 36.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU80627.1 - 1.1e-07 31.5 0.0 1.4e-06 28.0 0.0 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EAU80627.1 - 0.0099 15.8 1.1 0.52 10.3 0.4 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AlaDh_PNT_C PF01262.16 EAU80627.1 - 0.13 11.8 1.7 0.21 11.1 0.8 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4388 PF14332.1 EAU80630.2 - 0.003 17.3 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4388) YfhO PF09586.5 EAU80630.2 - 0.45 8.4 3.0 0.48 8.3 2.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3481 PF11980.3 EAU80631.2 - 0.083 12.7 0.6 0.26 11.1 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) zf-C2H2 PF00096.21 EAU80632.2 - 0.013 15.7 14.2 1.8 9.0 0.0 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EAU80632.2 - 0.081 13.1 7.8 0.51 10.6 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Clathrin PF00637.15 EAU80634.2 - 6.7e-17 61.4 0.4 1.3e-12 47.4 0.1 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.3 EAU80634.2 - 4.1e-06 26.5 0.3 8.8e-06 25.4 0.2 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EAU80634.2 - 0.0018 17.9 8.2 0.0029 17.2 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAU80634.2 - 0.0022 17.9 7.6 0.0038 17.2 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RPN7 PF10602.4 EAU80634.2 - 0.0054 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_11 PF13414.1 EAU80634.2 - 0.015 14.8 0.0 0.06 13.0 0.0 2.0 2 0 0 2 2 2 0 TPR repeat FliG_N PF14842.1 EAU80634.2 - 0.027 14.5 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 FliG N-terminal domain zf-RING_2 PF13639.1 EAU80634.2 - 0.04 13.7 9.1 0.076 12.8 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 EAU80634.2 - 0.26 11.0 2.0 0.58 9.9 1.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EAU80634.2 - 7 6.4 8.4 13 5.5 5.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cerato-platanin PF07249.7 EAU80636.2 - 1.5e-26 92.7 0.3 1.8e-26 92.4 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin DPBB_1 PF03330.13 EAU80636.2 - 0.064 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel GFA PF04828.9 EAU80637.2 - 1.1e-17 63.7 0.3 1.5e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 EAU80637.2 - 0.027 14.7 3.0 1.3 9.3 0.4 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_ribbon_recom PF13408.1 EAU80637.2 - 0.16 12.2 1.3 1.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Hydrophobin PF01185.13 EAU80639.1 - 2e-21 76.2 15.1 2.5e-21 75.9 10.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_9 PF02819.10 EAU80639.1 - 1.7 8.7 6.7 0.54 10.3 0.6 2.2 2 0 0 2 2 2 0 Spider toxin HSF_DNA-bind PF00447.12 EAU80641.1 - 8.5e-36 122.2 0.6 1.4e-35 121.5 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding gag-asp_proteas PF13975.1 EAU80641.1 - 0.13 12.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease 4HBT_3 PF13622.1 EAU80644.1 - 4.7e-39 134.6 1.1 5.6e-39 134.4 0.7 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_hydro_11 PF00457.12 EAU80651.2 - 2.4e-51 173.7 4.4 2.9e-51 173.4 3.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 F-box-like PF12937.2 EAU80652.1 - 1.1e-09 37.8 0.0 3e-09 36.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU80652.1 - 0.00031 20.2 0.3 0.0014 18.2 0.2 2.2 1 1 0 1 1 1 1 F-box domain DUF4360 PF14273.1 EAU80661.2 - 6.3e-22 78.1 0.1 1.3e-21 77.0 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.1 EAU80662.2 - 8.2e-12 45.1 0.0 1e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase PF00069.20 EAU80664.2 - 5.3e-09 35.6 0.0 8.3e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SWIM PF04434.12 EAU80667.2 - 0.0019 17.6 0.3 0.0047 16.3 0.2 1.7 1 0 0 1 1 1 1 SWIM zinc finger DPM2 PF07297.7 EAU80667.2 - 0.039 14.2 0.1 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) F-box-like PF12937.2 EAU80668.2 - 9.8e-15 54.0 0.1 2.3e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU80668.2 - 1e-06 28.2 0.0 3.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain Glyco_hydro_6 PF01341.12 EAU80669.1 - 1.6e-88 296.9 2.5 2e-88 296.6 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_6 PF01341.12 EAU80670.2 - 1.3e-86 290.7 0.3 1.6e-86 290.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Response_reg PF00072.19 EAU80672.1 - 1.7e-22 79.5 0.1 2.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HSF_DNA-bind PF00447.12 EAU80674.2 - 1.4e-35 121.6 0.6 2.4e-35 120.8 0.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding CCDC92 PF14916.1 EAU80674.2 - 0.0018 17.8 0.3 0.0047 16.4 0.2 1.6 1 0 0 1 1 1 1 Coiled-coil domain of unknown function Leu_zip PF15294.1 EAU80674.2 - 0.0029 16.7 0.0 0.0029 16.7 0.0 1.5 2 0 0 2 2 2 1 Leucine zipper Dehydrin PF00257.14 EAU80674.2 - 0.0088 16.3 3.3 0.056 13.7 2.3 2.4 1 1 0 1 1 1 1 Dehydrin DivIC PF04977.10 EAU80674.2 - 0.045 13.2 3.8 0.22 11.0 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4404 PF14357.1 EAU80674.2 - 1.2 9.6 4.5 9.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CFEM PF05730.6 EAU80675.2 - 3.2e-07 30.0 7.6 5.7e-07 29.2 5.3 1.4 1 0 0 1 1 1 1 CFEM domain ABC_tran PF00005.22 EAU80676.2 - 1.5e-14 54.4 0.0 1e-13 51.7 0.0 2.3 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EAU80676.2 - 5.8e-05 22.5 0.2 0.00017 21.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EAU80676.2 - 0.00011 22.2 0.0 0.057 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU80676.2 - 0.00033 20.6 0.0 0.0022 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EAU80676.2 - 0.0029 17.0 0.1 0.17 11.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EAU80676.2 - 0.0033 16.8 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU80676.2 - 0.007 17.1 0.0 0.018 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU80676.2 - 0.016 14.9 0.0 0.054 13.2 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EAU80676.2 - 0.017 15.2 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EAU80676.2 - 0.029 13.7 1.1 0.1 12.0 0.7 1.9 1 1 1 2 2 2 0 AAA-like domain AAA_30 PF13604.1 EAU80676.2 - 0.032 13.8 0.1 0.078 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EAU80676.2 - 0.04 13.0 0.1 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 EAU80676.2 - 0.046 12.9 0.1 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EAU80676.2 - 0.047 13.3 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EAU80676.2 - 0.055 12.9 0.6 0.14 11.5 0.3 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family TraD_N PF12615.3 EAU80676.2 - 0.065 13.5 2.2 2.9 8.3 0.0 2.8 2 1 0 2 2 2 0 F sex factor protein N terminal AAA_33 PF13671.1 EAU80676.2 - 0.1 12.4 0.2 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU80676.2 - 0.14 11.7 0.2 0.41 10.2 0.1 1.8 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 EAU80676.2 - 0.15 10.9 0.2 0.29 9.9 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EAU80676.2 - 0.18 11.6 0.3 5.3 6.8 0.3 2.4 2 0 0 2 2 2 0 Dynamin family DUF3987 PF13148.1 EAU80676.2 - 0.18 10.3 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Cellulase PF00150.13 EAU80677.2 - 2.8e-09 36.5 0.0 4.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3753 PF12575.3 EAU80677.2 - 0.17 11.6 0.4 0.32 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) WD40 PF00400.27 EAU80678.2 - 1.4e-145 468.6 39.4 4.2e-12 45.4 0.0 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat NACHT PF05729.7 EAU80678.2 - 2.1e-09 37.2 0.0 3.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EAU80678.2 - 9.4e-07 28.3 2.5 4 7.2 0.0 7.7 8 0 0 8 8 7 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EAU80678.2 - 9.8e-07 27.9 5.7 0.47 9.8 0.0 7.2 8 0 0 8 8 8 2 Proteasome subunit A N-terminal signature Nup160 PF11715.3 EAU80678.2 - 3.8e-06 25.3 9.2 1.3 7.0 0.1 7.1 5 4 2 7 7 7 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAU80678.2 - 3.3e-05 22.8 5.7 0.87 8.2 0.0 5.6 3 2 1 6 6 6 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EAU80678.2 - 6.1e-05 21.4 0.1 0.13 10.5 0.0 4.1 4 2 0 4 4 4 1 Cytochrome D1 heme domain AAA PF00004.24 EAU80678.2 - 7.8e-05 22.8 0.0 0.00024 21.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_S9_N PF02897.10 EAU80678.2 - 0.00053 18.6 0.2 2.1 6.8 0.0 4.6 4 2 1 5 5 5 1 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_16 PF13191.1 EAU80678.2 - 0.00075 19.5 0.3 0.0035 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU80678.2 - 0.0021 18.2 0.1 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain PQQ_2 PF13360.1 EAU80678.2 - 0.013 15.0 7.2 7.4 5.9 0.0 4.8 2 1 3 5 5 5 0 PQQ-like domain DUF2075 PF09848.4 EAU80678.2 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EAU80678.2 - 0.095 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EAU80678.2 - 0.11 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain PQQ_3 PF13570.1 EAU80678.2 - 0.11 12.8 13.9 2.2 8.6 0.0 6.7 6 1 1 7 7 6 0 PQQ-like domain NB-ARC PF00931.17 EAU80678.2 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.15 EAU80678.2 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Ras PF00071.17 EAU80679.1 - 1.3e-50 170.9 0.0 4.4e-50 169.2 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EAU80679.1 - 1.1e-13 51.6 0.0 1.7e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU80679.1 - 1.9e-11 43.5 0.0 2.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU80679.1 - 0.00069 19.0 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAU80679.1 - 0.0028 17.5 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SSP160 PF06933.6 EAU80679.1 - 9.3 4.0 11.9 13 3.6 8.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DEAD PF00270.24 EAU80684.1 - 1.2e-42 145.2 2.3 3.9e-42 143.6 0.5 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU80684.1 - 4.2e-27 93.8 0.3 2.4e-26 91.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EAU80684.1 - 0.00074 19.2 0.2 0.0022 17.6 0.0 1.9 1 1 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EAU80684.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EAU80684.1 - 0.0072 15.9 0.8 0.018 14.6 0.3 1.8 2 1 0 2 2 2 1 AAA domain DUF1253 PF06862.7 EAU80684.1 - 0.05 12.0 0.1 1.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Flavi_DEAD PF07652.9 EAU80684.1 - 0.067 12.9 0.1 0.25 11.1 0.0 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 EAU80684.1 - 0.084 11.9 0.1 0.25 10.4 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DSPc PF00782.15 EAU80685.2 - 1e-23 83.3 0.0 1.2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAU80685.2 - 0.00029 20.2 0.0 0.00039 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EAU80685.2 - 0.0067 15.3 0.0 0.0081 15.0 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase MFS_1 PF07690.11 EAU80686.2 - 5.9e-25 87.7 76.0 6.5e-18 64.5 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EAU80686.2 - 8.2e-05 22.3 1.1 0.53 10.1 0.0 2.7 2 0 0 2 2 2 2 MFS_1 like family Sporozoite_P67 PF05642.6 EAU80686.2 - 0.087 10.6 1.4 0.12 10.2 1.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spc7 PF08317.6 EAU80690.2 - 0.71 8.4 29.1 0.034 12.8 8.1 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF489 PF04356.7 EAU80690.2 - 1.6 8.2 11.3 0.14 11.6 1.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF489) F-box-like PF12937.2 EAU80692.1 - 1.8e-09 37.1 0.5 5.3e-09 35.6 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU80692.1 - 0.00032 20.2 0.6 0.0013 18.2 0.4 2.1 1 1 0 1 1 1 1 F-box domain DUF4418 PF14387.1 EAU80693.2 - 0.14 11.9 0.4 0.42 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) zf-CCHC PF00098.18 EAU80696.2 - 2.1e-54 178.9 59.2 6.4e-09 35.3 1.2 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EAU80696.2 - 1.8e-11 43.5 46.9 0.018 14.6 1.1 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EAU80696.2 - 5.8e-09 35.5 41.5 0.072 12.8 0.1 7.0 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 EAU80696.2 - 2.6e-06 26.8 42.4 0.26 10.8 0.4 7.2 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 EAU80696.2 - 0.00061 19.4 51.3 0.03 13.9 0.3 7.1 6 1 1 7 7 7 6 Zinc knuckle COX4 PF02936.9 EAU80697.1 - 8.9e-34 116.2 0.0 1.2e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Unstab_antitox PF09720.5 EAU80697.1 - 0.17 11.6 2.7 0.2 11.3 0.0 2.3 2 1 0 2 2 2 0 Putative addiction module component DUF2613 PF11021.3 EAU80697.1 - 0.89 9.3 0.0 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Solute_trans_a PF03619.11 EAU80699.2 - 7.9e-43 146.7 16.0 7.3e-25 87.8 3.9 3.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha Fibrillarin PF01269.12 EAU80700.1 - 9.5e-104 345.3 0.0 1.1e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EAU80700.1 - 1.6e-05 24.5 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EAU80700.1 - 0.0023 18.5 0.0 0.0033 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAU80700.1 - 0.0025 17.3 0.1 0.0044 16.5 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EAU80700.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PMT PF02366.13 EAU80701.2 - 7e-79 264.6 18.0 7e-79 264.6 12.5 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EAU80701.2 - 3.7e-31 108.1 0.7 5.1e-31 107.6 0.5 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 EAU80701.2 - 0.00022 21.1 13.4 0.00022 21.1 9.3 2.9 3 0 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Thionin PF00321.12 EAU80702.1 - 0.064 13.4 12.8 2.4 8.4 0.5 2.6 1 1 1 2 2 2 0 Plant thionin Amnionless PF14828.1 EAU80702.1 - 0.86 8.0 7.3 1.1 7.7 5.1 1.0 1 0 0 1 1 1 0 Amnionless MFS_1 PF07690.11 EAU80704.2 - 7.1e-20 71.0 75.7 5.9e-17 61.4 30.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_J PF04911.7 EAU80704.2 - 1.9 8.0 4.4 7.2 6.1 0.5 3.0 2 1 1 3 3 3 0 ATP synthase j chain ING PF12998.2 EAU80706.1 - 1.8e-14 53.8 0.1 2.8e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EAU80706.1 - 1.9e-08 33.8 9.7 3e-08 33.2 6.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EAU80706.1 - 0.027 14.6 0.3 0.058 13.5 0.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hydrophobin PF01185.13 EAU80707.1 - 1.6e-21 76.4 14.5 2.1e-21 76.1 10.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin FAD_binding_4 PF01565.18 EAU80708.1 - 1.4e-19 69.9 0.1 2.6e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU80708.1 - 4.7e-13 48.8 0.1 1e-12 47.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Acetyltransf_1 PF00583.19 EAU80718.1 - 3.3e-15 55.8 0.0 6.6e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU80718.1 - 3.1e-12 46.4 0.0 5.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU80718.1 - 1.1e-05 25.2 0.0 6.6e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAU80718.1 - 1.3e-05 25.3 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU80718.1 - 1.9e-05 24.6 0.0 4.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAU80718.1 - 0.00022 21.3 0.0 0.00069 19.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAU80718.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EAU80718.1 - 0.0022 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EAU80718.1 - 0.0096 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EAU80718.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF3749 PF12568.3 EAU80718.1 - 0.028 14.0 0.0 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Piwi PF02171.12 EAU80720.2 - 1e-76 257.8 0.0 1.4e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EAU80720.2 - 4e-15 54.9 0.0 8.5e-15 53.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EAU80720.2 - 1.6e-11 43.6 0.0 3.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Carn_acyltransf PF00755.15 EAU80725.2 - 4.5e-164 546.8 0.0 5.7e-164 546.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Clp1 PF06807.9 EAU80730.2 - 2.4e-09 37.2 0.0 4.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EAU80730.2 - 3.4e-08 33.2 0.0 5.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EAU80730.2 - 1.5e-05 24.7 0.0 3.5e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EAU80730.2 - 0.00029 20.7 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU80730.2 - 0.0019 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF566 PF04484.7 EAU80730.2 - 4.2 6.7 16.2 7.4 5.9 11.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) SAGA-Tad1 PF12767.2 EAU80730.2 - 8.1 6.0 10.3 14 5.2 7.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DnaJ PF00226.26 EAU80732.2 - 1.5e-19 69.4 1.9 1.5e-19 69.4 1.3 1.7 2 0 0 2 2 2 1 DnaJ domain Hydrophobin PF01185.13 EAU80733.1 - 1.8e-22 79.5 12.4 2.2e-22 79.3 8.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_30 PF08117.6 EAU80733.1 - 9.3 6.3 11.3 12 6.0 1.0 2.3 2 0 0 2 2 2 0 Ptu family 5_nucleotid_C PF02872.13 EAU80734.1 - 1.6e-26 93.1 0.0 3.2e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EAU80734.1 - 3.4e-11 42.9 0.1 7.7e-11 41.7 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EAU80734.1 - 0.00013 21.4 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Piwi PF02171.12 EAU80736.2 - 5.7e-50 169.9 0.0 4.2e-43 147.4 0.0 2.7 2 1 1 3 3 3 2 Piwi domain DUF1785 PF08699.5 EAU80736.2 - 1e-12 47.2 0.0 2.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EAU80736.2 - 5.2e-09 35.5 0.0 1.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 PAZ domain VWA PF00092.23 EAU80736.2 - 0.028 14.1 0.0 11 5.6 0.0 2.9 2 1 1 3 3 3 0 von Willebrand factor type A domain Methyltransf_PK PF05891.7 EAU80736.2 - 0.15 11.3 0.0 0.45 9.7 0.0 1.8 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Glyco_hydro_61 PF03443.9 EAU80738.1 - 2.7e-44 151.6 0.0 3.1e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EAU80739.1 - 2.7e-44 151.5 0.0 3.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Mur_ligase_M PF08245.7 EAU80740.2 - 2.2e-05 24.6 0.0 3.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain TOMM6 PF15184.1 EAU80740.2 - 0.037 13.3 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog FAM60A PF15396.1 EAU80741.1 - 0.086 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A ABC_membrane PF00664.18 EAU80745.2 - 2.4e-88 296.1 19.7 7.8e-50 169.8 3.1 3.0 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAU80745.2 - 1e-56 191.0 0.0 6.3e-34 117.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAU80745.2 - 2.5e-09 37.5 0.2 0.022 14.7 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAU80745.2 - 1.3e-07 31.0 6.6 0.0071 15.8 0.0 3.8 4 0 0 4 4 4 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EAU80745.2 - 5.4e-07 30.4 0.0 0.03 15.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAU80745.2 - 4.7e-06 25.8 0.0 0.12 11.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 SMC_N PF02463.14 EAU80745.2 - 6.8e-06 25.4 4.7 0.0026 17.0 0.0 3.8 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EAU80745.2 - 3e-05 24.0 4.0 0.016 15.2 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EAU80745.2 - 0.00013 22.0 1.0 0.88 9.7 0.0 3.4 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EAU80745.2 - 0.0003 19.9 0.0 0.29 10.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EAU80745.2 - 0.00031 21.0 0.2 0.42 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EAU80745.2 - 0.00035 20.4 0.0 0.45 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EAU80745.2 - 0.002 17.6 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_19 PF13245.1 EAU80745.2 - 0.0025 17.5 0.0 4.2 7.1 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain ABC_ATPase PF09818.4 EAU80745.2 - 0.0039 15.8 0.3 0.024 13.2 0.1 2.2 3 0 0 3 3 3 1 Predicted ATPase of the ABC class MobB PF03205.9 EAU80745.2 - 0.0044 16.7 0.2 1.2 8.8 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 EAU80745.2 - 0.0061 15.2 5.2 0.17 10.5 0.0 2.9 3 0 0 3 3 3 1 G-protein alpha subunit AAA_25 PF13481.1 EAU80745.2 - 0.0064 15.9 3.0 2.2 7.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain DUF815 PF05673.8 EAU80745.2 - 0.0088 15.0 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) DUF3987 PF13148.1 EAU80745.2 - 0.011 14.3 0.0 0.096 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) APS_kinase PF01583.15 EAU80745.2 - 0.011 15.3 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.1 EAU80745.2 - 0.012 15.9 0.0 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EAU80745.2 - 0.018 15.0 0.5 3 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.1 EAU80745.2 - 0.018 14.5 5.2 3.6 7.1 0.0 3.7 4 1 0 4 4 4 0 AAA domain AAA_5 PF07728.9 EAU80745.2 - 0.023 14.4 0.0 3.8 7.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EAU80745.2 - 0.029 14.2 0.5 4.2 7.1 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EAU80745.2 - 0.031 14.2 0.0 8.5 6.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EAU80745.2 - 0.066 12.6 1.7 7.2 5.9 0.1 2.6 3 0 0 3 3 2 0 AAA-like domain SbcCD_C PF13558.1 EAU80745.2 - 0.18 11.7 1.3 0.85 9.5 0.1 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EAU80745.2 - 0.19 11.8 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EAU80745.2 - 0.32 9.9 0.0 20 4.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PP2C PF00481.16 EAU80748.2 - 4.7e-07 29.4 0.0 2.1e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C CBM_14 PF01607.19 EAU80749.2 - 0.042 13.7 0.1 0.061 13.2 0.1 1.2 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain CBM_19 PF03427.8 EAU80749.2 - 0.068 12.9 0.1 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) ARF7EP_C PF14949.1 EAU80751.2 - 0.065 13.6 2.3 0.074 13.4 1.6 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Glyco_hydro_31 PF01055.21 EAU80752.2 - 5.4e-146 486.8 0.0 1.3e-104 350.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAU80752.2 - 1.9e-09 37.2 0.4 5.1e-09 35.8 0.3 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like DUF2523 PF10734.4 EAU80753.2 - 0.0084 16.3 0.5 0.017 15.2 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2523) Pkinase PF00069.20 EAU80755.2 - 2e-50 171.4 0.0 3.1e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80755.2 - 2.3e-23 82.6 0.0 5.7e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EAU80755.2 - 0.0051 15.6 0.1 0.0074 15.1 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EAU80755.2 - 0.044 13.5 0.1 0.28 10.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YL1 PF05764.8 EAU80755.2 - 5.5 6.5 14.7 0.37 10.3 6.5 1.6 2 0 0 2 2 2 0 YL1 nuclear protein p450 PF00067.17 EAU80756.1 - 1e-64 218.7 0.0 1.2e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fumarate_red_D PF02313.12 EAU80759.2 - 0.38 10.6 2.7 1 9.2 1.9 1.7 1 1 0 1 1 1 0 Fumarate reductase subunit D Glyco_hydro_18 PF00704.23 EAU80760.2 - 1.5e-94 317.2 0.1 1.8e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.20 EAU80763.1 - 3.5e-23 82.3 0.1 6.2e-23 81.5 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU80763.1 - 6.8e-11 42.1 0.0 1.7e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU80763.1 - 5.3e-06 26.3 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAU80763.1 - 8.4e-05 22.6 0.0 0.0028 17.6 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAU80763.1 - 0.018 13.7 0.0 0.11 11.1 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAU80763.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shugoshin_C PF07557.6 EAU80764.1 - 8.7e-10 37.8 3.5 8.7e-10 37.8 2.4 4.7 6 0 0 6 6 6 1 Shugoshin C terminus Shugoshin_N PF07558.6 EAU80764.1 - 1.3e-05 24.7 2.2 2.7e-05 23.7 1.5 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EAU80764.1 - 3 7.3 5.6 1.1 8.8 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator Hydrophobin PF01185.13 EAU80765.2 - 1.1e-16 61.0 8.4 1.4e-16 60.6 5.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_30 PF08117.6 EAU80765.2 - 4.1 7.5 9.5 0.52 10.3 1.1 2.3 2 0 0 2 2 2 0 Ptu family Glyco_hydro_31 PF01055.21 EAU80766.2 - 6.7e-163 542.5 0.3 1e-162 542.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAU80766.2 - 1.2e-09 37.8 1.5 4.5e-09 36.0 1.1 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like MMR_HSR1 PF01926.18 EAU80767.2 - 3.2e-07 30.2 0.0 6.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EAU80767.2 - 1.1e-05 24.6 0.0 3e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Septin AIG1 PF04548.11 EAU80767.2 - 2.7e-05 23.4 0.0 7.9e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 AIG1 family ABC_tran PF00005.22 EAU80767.2 - 0.00011 22.5 0.1 0.00042 20.6 0.0 1.9 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EAU80767.2 - 0.00012 21.2 0.2 0.00099 18.3 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EAU80767.2 - 0.0011 18.7 3.5 0.68 9.7 0.0 2.8 2 1 0 3 3 3 2 Dynamin family AAA_18 PF13238.1 EAU80767.2 - 0.0015 18.8 0.1 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EAU80767.2 - 0.0029 17.0 0.1 0.0061 16.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EAU80767.2 - 0.0034 16.8 2.9 0.15 11.4 2.0 2.2 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EAU80767.2 - 0.0058 16.6 0.4 0.27 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EAU80767.2 - 0.016 14.6 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU80767.2 - 0.044 14.1 2.3 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EAU80767.2 - 0.046 12.6 0.0 0.085 11.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EAU80767.2 - 0.048 13.1 0.1 0.14 11.5 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EAU80767.2 - 0.1 11.4 0.0 0.35 9.6 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.1 EAU80767.2 - 0.14 12.3 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EAU80767.2 - 0.14 11.6 0.2 11 5.4 0.1 2.6 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EAU80767.2 - 0.15 12.9 1.7 1.1 10.1 1.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU80767.2 - 0.42 10.4 2.8 0.81 9.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain Vpu PF00558.14 EAU80768.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Vpu protein OppC_N PF12911.2 EAU80769.1 - 0.027 13.8 0.1 0.069 12.5 0.1 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C CathepsinC_exc PF08773.6 EAU80770.1 - 0.089 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Cathepsin C exclusion domain DUF2763 PF10961.3 EAU80772.2 - 0.022 15.1 0.1 0.027 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Spore_YhaL PF14147.1 EAU80772.2 - 2.8 7.4 5.3 0.37 10.2 1.0 1.5 2 0 0 2 2 2 0 Sporulation protein YhaL INO80_Ies4 PF08193.6 EAU80775.1 - 0.033 14.1 0.1 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 FAD_binding_4 PF01565.18 EAU80782.2 - 7.1e-21 74.1 0.2 1.2e-20 73.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU80782.2 - 2e-14 53.2 0.2 4.3e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Hydrophobin PF01185.13 EAU80783.1 - 1.7e-18 66.8 14.3 2.1e-18 66.5 9.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF3760 PF12586.3 EAU80784.1 - 0.0061 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3760) zf-C2H2 PF00096.21 EAU80785.2 - 2.4e-08 33.8 10.4 5.9e-05 23.1 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU80785.2 - 3.2e-06 27.0 9.0 0.0072 16.5 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU80785.2 - 8.7e-06 25.7 3.3 3e-05 24.0 2.3 2.0 1 0 0 1 1 1 1 Zinc-finger double domain eIF-1a PF01176.14 EAU80786.2 - 0.12 11.8 0.0 18 4.8 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 EAU80789.2 - 5.4e-41 140.4 0.0 2.8e-22 79.1 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80789.2 - 2e-12 46.7 7.9 9e-05 21.6 0.2 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase PrmA PF06325.8 EAU80789.2 - 0.04 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_ser-thr_kin PF05445.6 EAU80789.2 - 0.063 12.0 0.1 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Glyco_hydro_3_C PF01915.17 EAU80790.2 - 3.2e-69 232.9 0.1 8.5e-68 228.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EAU80790.2 - 4.6e-68 229.4 0.0 6.3e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EAU80790.2 - 6.9e-19 67.5 0.6 1.7e-18 66.3 0.3 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EAU80790.2 - 3.9e-11 42.7 0.0 7.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PQQ PF01011.16 EAU80795.1 - 0.057 12.9 7.1 0.68 9.5 0.1 3.2 1 1 2 3 3 3 0 PQQ enzyme repeat Mito_fiss_reg PF05308.6 EAU80802.2 - 0.41 9.9 4.5 0.49 9.7 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 EAU80804.2 - 1.9e-32 112.3 28.4 1.9e-32 112.3 19.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU80804.2 - 8.3e-09 34.5 11.9 8.3e-09 34.5 8.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PEN-2 PF10251.4 EAU80805.2 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase AflR PF08493.5 EAU80805.2 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Glyco_hydro_61 PF03443.9 EAU80807.2 - 2.9e-60 203.7 0.1 3.6e-60 203.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAU80807.2 - 9.3e-11 41.1 9.9 3.2e-10 39.5 6.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain zf-C2H2 PF00096.21 EAU80808.1 - 0.0071 16.6 0.1 0.017 15.4 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-MYND PF01753.13 EAU80810.2 - 8.6e-11 41.5 3.2 2e-10 40.3 2.2 1.6 1 0 0 1 1 1 1 MYND finger WGG PF10273.4 EAU80810.2 - 0.099 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 Amastin PF07344.6 EAU80812.2 - 0.0016 18.0 1.2 0.0032 17.1 0.8 1.5 1 0 0 1 1 1 1 Amastin surface glycoprotein PsbJ PF01788.12 EAU80812.2 - 0.32 10.5 2.3 6.3 6.4 0.1 2.5 2 0 0 2 2 2 0 PsbJ FAD_binding_4 PF01565.18 EAU80813.2 - 7.7e-17 61.0 1.3 1.6e-16 60.0 0.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU80813.2 - 5.7e-08 32.5 0.1 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TGT PF01702.13 EAU80814.2 - 1.6e-18 66.8 3.5 8.4e-09 35.0 0.0 4.0 5 0 0 5 5 5 3 Queuine tRNA-ribosyltransferase Tyr-DNA_phospho PF06087.7 EAU80814.2 - 0.15 10.6 2.8 0.78 8.2 0.0 2.1 2 0 0 2 2 2 0 Tyrosyl-DNA phosphodiesterase Peptidase_M28 PF04389.12 EAU80818.1 - 1.9e-34 118.9 0.0 2.8e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAU80818.1 - 9.1e-15 54.1 0.2 2.1e-14 53.0 0.1 1.7 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EAU80818.1 - 3.3e-06 26.7 0.0 6.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Grp1_Fun34_YaaH PF01184.14 EAU80823.1 - 8.9e-44 149.2 15.2 1.1e-43 149.0 10.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1649 PF07855.7 EAU80824.2 - 1.6e-11 44.1 0.6 1.7e-11 44.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) PHD PF00628.24 EAU80825.2 - 2.3e-06 27.1 5.5 1.3e-05 24.8 1.7 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EAU80825.2 - 0.001 18.7 2.6 0.001 18.7 1.8 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Reg_prop PF07494.6 EAU80825.2 - 0.06 13.3 0.1 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Two component regulator propeller NAGLU PF05089.7 EAU80825.2 - 0.15 10.7 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain TerY-C PF15616.1 EAU80825.2 - 0.38 10.6 4.1 0.25 11.2 1.4 1.7 2 0 0 2 2 2 0 TerY-C metal binding domain zinc_ribbon_4 PF13717.1 EAU80825.2 - 0.73 9.5 4.9 0.61 9.8 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EAU80825.2 - 1 9.0 5.0 0.73 9.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 EAU80825.2 - 7.9 5.6 6.0 0.47 9.5 0.4 1.7 2 0 0 2 2 2 0 Mu-like prophage protein Com MFS_1 PF07690.11 EAU80827.1 - 6.2e-31 107.3 31.5 8.3e-31 106.9 21.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU80827.1 - 5.4e-11 41.7 3.8 5.4e-11 41.7 2.6 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter RAP1 PF07218.6 EAU80828.2 - 1.6 6.7 5.2 2.8 5.9 3.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LRR19-TM PF15176.1 EAU80829.2 - 1.1 8.9 3.4 2.5 7.8 2.4 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SDA1 PF05285.7 EAU80829.2 - 2.8 7.1 5.6 4.4 6.4 3.9 1.2 1 0 0 1 1 1 0 SDA1 Skp1 PF01466.14 EAU80830.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PIF1 PF05970.9 EAU80832.2 - 1.5e-29 103.1 0.0 7.6e-29 100.7 0.0 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAU80832.2 - 1.9e-05 24.3 0.0 0.00012 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 EAU80832.2 - 8.9e-05 22.2 0.0 0.00083 19.1 0.0 2.4 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.9 EAU80832.2 - 0.015 13.0 0.0 0.029 12.1 0.0 1.3 1 0 0 1 1 1 0 Helicase NB-ARC PF00931.17 EAU80832.2 - 0.036 12.9 0.0 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Peptidase_M28 PF04389.12 EAU80838.1 - 7.5e-31 107.2 0.0 1.3e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAU80838.1 - 1.1e-14 53.9 0.2 3.5e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EAU80838.1 - 0.00054 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 EAU80839.2 - 1.1e-09 37.5 21.4 1.1e-09 37.5 14.8 4.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Na_trans_assoc PF06512.8 EAU80845.1 - 0.0037 17.2 0.7 0.0051 16.8 0.5 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated Aminotran_1_2 PF00155.16 EAU80845.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II TPR_11 PF13414.1 EAU80848.2 - 0.048 13.3 0.0 1 9.0 0.0 2.6 3 0 0 3 3 3 0 TPR repeat Apo-CIII PF05778.7 EAU80848.2 - 0.075 12.4 0.1 11 5.4 0.0 2.7 2 1 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Asp PF00026.18 EAU80857.2 - 4.1e-31 108.4 0.0 4.5e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Herpes_gE PF02480.11 EAU80857.2 - 0.012 13.8 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4328 PF14219.1 EAU80857.2 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) DUF1049 PF06305.6 EAU80857.2 - 0.29 10.6 6.1 0.041 13.3 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3043 PF11241.3 EAU80858.2 - 1.6 8.2 6.0 2.2 7.8 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) EB1 PF03271.12 EAU80860.1 - 1.8e-16 59.8 3.4 4.1e-16 58.7 2.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EAU80860.1 - 2.3e-06 27.5 0.3 4.4e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EAU80860.1 - 0.022 12.9 0.0 0.027 12.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Suppressor_APC PF11414.3 EAU80860.1 - 0.023 14.4 2.1 0.042 13.6 1.4 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein FlxA PF14282.1 EAU80860.1 - 0.034 14.0 0.3 0.054 13.4 0.2 1.3 1 0 0 1 1 1 0 FlxA-like protein MFS_1 PF07690.11 EAU80861.2 - 1.7e-15 56.6 35.1 2.2e-11 43.1 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU80861.2 - 4.9e-05 22.1 3.2 4.9e-05 22.1 2.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter ATP-synt_Eps PF04627.8 EAU80863.1 - 0.47 10.0 5.3 9.2 5.9 0.8 2.6 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Phage_lysozyme PF00959.14 EAU80864.1 - 1.8e-18 66.8 0.0 2.6e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme NAAA-beta PF15508.1 EAU80865.2 - 7.9e-22 77.4 0.0 1.6e-21 76.4 0.0 1.5 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Phage_lysozyme PF00959.14 EAU80866.1 - 7.5e-19 68.0 0.0 1.1e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme Picorna_P3A PF06363.6 EAU80866.1 - 0.0025 17.7 0.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 2 Picornaviridae P3A protein zf-RING_2 PF13639.1 EAU80868.2 - 7.5e-14 51.2 5.5 1.2e-13 50.6 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAU80868.2 - 3e-08 33.5 4.5 5e-08 32.8 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAU80868.2 - 3.3e-08 33.5 4.4 6.1e-08 32.6 3.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAU80868.2 - 9.1e-08 31.6 5.2 1.5e-07 30.9 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU80868.2 - 7.7e-07 28.6 3.2 1.2e-06 28.0 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU80868.2 - 1.1e-06 28.2 4.6 1.7e-06 27.6 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EAU80868.2 - 2.3e-05 24.1 2.0 4.5e-05 23.2 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EAU80868.2 - 0.0011 18.5 6.7 0.0018 17.8 4.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EAU80868.2 - 0.0077 16.2 3.5 0.014 15.3 2.4 1.4 1 0 0 1 1 1 1 RING-like domain RINGv PF12906.2 EAU80868.2 - 0.011 15.7 5.9 0.019 15.0 4.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EAU80868.2 - 0.15 11.7 3.3 0.34 10.6 2.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EAU80868.2 - 1.2 9.1 4.0 2.6 8.0 2.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EAU80868.2 - 1.3 8.7 6.5 2.3 8.0 4.5 1.4 1 0 0 1 1 1 0 PHD-finger MFS_1 PF07690.11 EAU80869.2 - 5e-27 94.5 40.7 8.8e-25 87.1 22.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EAU80869.2 - 0.061 13.3 0.2 0.061 13.3 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Phage_lysozyme PF00959.14 EAU80871.2 - 1.2e-14 54.5 0.0 1.7e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Phage_lysozyme PF00959.14 EAU80873.1 - 3.6e-15 56.1 0.0 5.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme BTB PF00651.26 EAU80874.2 - 3.5e-07 30.2 0.0 9.4e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EAU80875.2 - 5.4e-08 32.8 0.0 1.3e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Abhydrolase_6 PF12697.2 EAU80876.2 - 5.6e-05 23.1 0.0 6.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_61 PF03443.9 EAU80877.2 - 8.9e-30 104.1 0.0 1.1e-29 103.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 VCBS PF13517.1 EAU80877.2 - 0.045 14.1 1.2 0.43 10.9 0.0 2.8 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4139 PF13598.1 EAU80878.2 - 1.3e-98 330.2 0.1 2.3e-95 319.5 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EAU80878.2 - 3e-24 85.4 3.6 6.7e-23 81.1 0.1 2.8 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) ATG16 PF08614.6 EAU80878.2 - 0.0056 16.5 0.5 0.0097 15.7 0.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Mcm10 PF09332.6 EAU80878.2 - 0.091 12.0 2.0 0.15 11.3 1.4 1.3 1 0 0 1 1 1 0 Mcm10 replication factor DUF641 PF04859.7 EAU80878.2 - 0.14 11.8 1.8 0.27 10.9 1.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.15 EAU80878.2 - 1.6 8.4 7.1 19 5.0 5.0 2.2 1 1 0 1 1 1 0 Prefoldin subunit SlyX PF04102.7 EAU80878.2 - 1.9 8.9 4.0 5.9 7.3 0.5 2.5 1 1 1 2 2 2 0 SlyX ETF PF01012.16 EAU80882.1 - 7.5e-22 77.7 0.2 9.7e-22 77.4 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Pro_CA PF00484.14 EAU80883.2 - 1.1e-31 109.8 0.0 3.1e-31 108.4 0.0 1.7 1 1 0 1 1 1 1 Carbonic anhydrase SMN PF06003.7 EAU80883.2 - 0.028 13.5 1.1 0.056 12.5 0.8 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) BTB PF00651.26 EAU80884.1 - 5.4e-09 36.0 0.0 1.8e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.2 EAU80884.1 - 1.4 8.7 4.8 0.17 11.7 0.2 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF605 PF04652.11 EAU80884.1 - 2.9 7.1 17.7 3.7 6.8 12.3 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EAU80886.2 - 4e-09 36.0 0.0 6.4e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80886.2 - 0.00021 20.4 0.0 0.00036 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU80887.2 - 4.7e-11 42.3 0.0 6.5e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80887.2 - 2.3e-05 23.5 0.0 3.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU80888.2 - 2.2e-09 36.8 0.0 3.2e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU80888.2 - 0.0008 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase BTB PF00651.26 EAU80889.1 - 1.7e-08 34.4 0.0 4.8e-08 32.9 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain DUF4139 PF13598.1 EAU80890.1 - 6.7e-98 327.8 0.4 1.5e-94 316.9 0.3 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EAU80890.1 - 9.2e-23 80.6 2.7 1.3e-20 73.7 0.0 3.0 2 1 1 3 3 3 2 N-terminal domain of unknown function (DUF4140) Osmo_CC PF08946.5 EAU80890.1 - 0.054 13.5 1.5 0.1 12.6 1.1 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil V_ATPase_I PF01496.14 EAU80890.1 - 0.19 9.5 0.5 0.26 9.0 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 EAU80890.1 - 0.2 11.9 1.7 0.36 11.1 0.5 1.9 2 0 0 2 2 2 0 Snapin/Pallidin Glyco_hydro_61 PF03443.9 EAU80891.2 - 9.9e-27 94.1 0.0 1.3e-25 90.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 VCBS PF13517.1 EAU80891.2 - 0.017 15.4 0.7 0.33 11.3 0.1 2.7 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Abhydrolase_6 PF12697.2 EAU80892.1 - 6e-23 81.9 0.8 1.1e-22 81.1 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU80892.1 - 2.8e-07 30.3 0.0 0.35 10.3 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold CMD PF02627.15 EAU80892.1 - 4.6e-07 29.5 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Abhydrolase_5 PF12695.2 EAU80892.1 - 1.9e-05 24.4 0.1 5.1e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAU80892.1 - 0.034 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase UQ_con PF00179.21 EAU80894.2 - 1e-38 131.9 0.0 1.4e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EAU80894.2 - 2.1e-18 65.6 0.0 2.9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EAU80894.2 - 0.00064 19.4 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B ArfGap PF01412.13 EAU80895.2 - 1e-32 112.3 2.4 1.2e-32 112.1 0.7 1.7 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf XPG_I PF00867.13 EAU80898.1 - 1.5e-17 63.4 0.0 3.6e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAU80898.1 - 0.0001 22.5 0.0 0.00033 20.8 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain BTB PF00651.26 EAU80899.1 - 2.7e-06 27.3 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Phage_lysozyme PF00959.14 EAU80900.1 - 5.1e-19 68.5 0.0 8.6e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme DUF4139 PF13598.1 EAU80901.1 - 1.5e-86 290.6 2.0 6.8e-86 288.4 1.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EAU80901.1 - 1.1e-22 80.4 4.6 2.7e-22 79.1 0.2 3.1 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) CO_deh_flav_C PF03450.12 EAU80901.1 - 0.086 12.7 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain DUF202 PF02656.10 EAU80903.1 - 2.7e-18 65.9 0.5 2.7e-18 65.9 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3082 PF11282.3 EAU80903.1 - 0.067 13.2 1.2 0.68 10.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3082) MFS_1 PF07690.11 EAU80906.2 - 6.1e-23 81.0 39.6 4.9e-20 71.5 22.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EAU80906.2 - 0.001 17.6 3.6 0.0073 14.8 2.3 2.0 2 0 0 2 2 2 1 Reduced folate carrier TPP_enzyme_N PF02776.13 EAU80907.1 - 2e-34 118.5 0.1 3.9e-34 117.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EAU80907.1 - 3e-12 46.3 0.2 7.5e-12 45.0 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAU80907.1 - 3.9e-08 33.1 0.0 2.9e-07 30.3 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain F-box-like PF12937.2 EAU80908.2 - 0.007 16.0 0.1 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU80908.2 - 0.051 13.2 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain Clat_adaptor_s PF01217.15 EAU80909.1 - 2.3e-56 189.4 3.6 2.5e-56 189.3 2.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ferric_reduct PF01794.14 EAU80911.1 - 3.9e-18 65.7 15.2 3.9e-18 65.7 10.5 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EAU80911.1 - 5.2e-06 27.0 0.0 9.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EAU80911.1 - 1.7e-05 24.7 0.2 0.024 14.5 0.1 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAU80911.1 - 5.4e-05 23.0 0.1 0.0022 17.8 0.1 2.5 1 1 0 1 1 1 1 FAD-binding domain DUF2427 PF10348.4 EAU80911.1 - 0.01 15.3 0.6 0.01 15.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Abi PF02517.11 EAU80912.2 - 9.2e-05 22.5 1.7 0.00088 19.3 0.5 2.4 2 1 0 2 2 2 1 CAAX protease self-immunity DUF2371 PF10177.4 EAU80912.2 - 0.027 14.3 0.2 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Pyr_redox_3 PF13738.1 EAU80914.1 - 3.8e-23 82.6 0.0 8.4e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU80914.1 - 1.8e-09 37.5 0.0 0.0014 18.4 0.0 3.8 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EAU80914.1 - 1.2e-08 34.2 0.2 3.3e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAU80914.1 - 1.3e-08 34.7 2.3 2.2e-07 30.7 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU80914.1 - 7.3e-08 32.5 0.3 0.00042 20.2 0.0 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EAU80914.1 - 4.1e-07 30.2 0.1 0.027 14.7 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding FMO-like PF00743.14 EAU80914.1 - 7.2e-07 27.7 0.0 7e-06 24.5 0.0 2.5 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 EAU80914.1 - 8.8e-07 29.2 0.9 0.00023 21.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU80914.1 - 1.2e-06 27.7 1.9 0.0022 16.9 0.1 3.4 2 1 0 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EAU80914.1 - 3.1e-06 27.3 0.2 0.11 12.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EAU80914.1 - 5e-05 22.5 0.4 0.0034 16.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EAU80914.1 - 0.00022 20.3 0.6 0.054 12.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EAU80914.1 - 0.00081 18.5 0.0 0.0068 15.5 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EAU80914.1 - 0.00094 18.1 1.7 0.0056 15.5 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 EAU80914.1 - 0.0015 17.4 0.5 0.18 10.6 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A CPSase_L_chain PF00289.17 EAU80914.1 - 0.0022 18.0 0.1 4.1 7.5 0.0 3.1 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 EAU80914.1 - 0.0026 16.7 0.5 2.6 6.8 0.1 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein 3HCDH_N PF02737.13 EAU80914.1 - 0.0042 16.7 1.0 0.13 11.8 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAU80914.1 - 0.015 15.2 0.2 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 EAU80914.1 - 0.02 13.3 0.1 0.02 13.3 0.0 2.5 4 0 0 4 4 4 0 HI0933-like protein XdhC_C PF13478.1 EAU80914.1 - 0.02 15.1 0.1 0.058 13.7 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain YjeF_N PF03853.10 EAU80914.1 - 0.078 12.5 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF4147 PF13660.1 EAU80914.1 - 0.096 11.7 0.2 0.55 9.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) ThiF PF00899.16 EAU80914.1 - 0.1 12.4 0.7 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.12 EAU80914.1 - 0.16 12.4 0.3 32 5.0 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EAU80914.1 - 0.18 11.2 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EAU80914.1 - 0.63 9.3 2.5 0.36 10.1 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VCBS PF13517.1 EAU80915.2 - 1.9e-21 76.1 28.8 2.1e-06 28.0 2.3 5.5 3 2 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EAU80915.2 - 0.015 14.9 2.7 0.015 14.9 1.9 5.8 5 1 1 6 6 6 0 FG-GAP repeat TcdB_toxin_midN PF12256.3 EAU80915.2 - 3.2 7.1 10.6 19 4.6 0.2 4.3 4 1 1 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region BTB PF00651.26 EAU80916.2 - 1.5e-06 28.1 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CDC45 PF02724.9 EAU80916.2 - 0.017 13.1 3.7 0.027 12.5 2.6 1.3 1 0 0 1 1 1 0 CDC45-like protein TrbI PF03743.9 EAU80916.2 - 0.093 12.2 0.2 0.21 11.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Sec3_C PF09763.4 EAU80916.2 - 0.6 8.1 4.1 0.84 7.6 2.8 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 EAU80916.2 - 0.73 8.0 10.3 1 7.5 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein FAM176 PF14851.1 EAU80916.2 - 0.9 9.2 3.5 1.5 8.4 2.4 1.3 1 0 0 1 1 1 0 FAM176 family Na_trans_assoc PF06512.8 EAU80916.2 - 1.2 9.1 5.1 1.7 8.5 3.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated RAP1 PF07218.6 EAU80916.2 - 3 5.8 11.9 3.8 5.4 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nop14 PF04147.7 EAU80916.2 - 4.7 4.9 8.2 6.5 4.5 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.4 EAU80916.2 - 9.3 4.9 11.3 13 4.4 7.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BTB PF00651.26 EAU80918.2 - 0.046 13.7 0.0 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 BTB/POZ domain Chitin_synth_1 PF01644.12 EAU80919.2 - 6.1e-85 283.0 0.2 8.5e-85 282.5 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EAU80919.2 - 6.1e-32 109.1 0.1 2.1e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EAU80919.2 - 9.4e-24 83.6 0.4 1.1e-17 63.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EAU80919.2 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EAU80919.2 - 0.00094 18.9 17.5 0.016 14.9 12.1 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF973 PF06157.6 EAU80919.2 - 0.0041 16.1 2.7 0.0069 15.3 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF973) Pkinase PF00069.20 EAU80920.1 - 5.6e-08 32.2 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAU80920.1 - 2.6e-05 23.3 0.0 4.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU80920.1 - 0.00065 19.4 2.5 0.0027 17.4 0.2 2.7 2 2 2 4 4 4 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EAU80920.1 - 0.0016 17.5 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU80920.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MMR_HSR1 PF01926.18 EAU80922.1 - 9.4e-10 38.4 0.0 1.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU80922.1 - 1.4e-06 27.5 0.0 2.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EAU80922.1 - 1.6e-06 28.0 0.4 4.1e-06 26.7 0.1 1.7 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 EAU80922.1 - 1.8e-06 28.4 0.0 3.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EAU80922.1 - 4e-05 23.0 0.0 7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Ras family DUF258 PF03193.11 EAU80922.1 - 6.3e-05 22.2 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EAU80922.1 - 0.00021 21.5 0.1 0.001 19.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter IIGP PF05049.8 EAU80922.1 - 0.00096 18.0 0.1 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 EAU80922.1 - 0.0024 17.1 0.1 0.0037 16.5 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_10 PF12846.2 EAU80922.1 - 0.0033 16.9 0.1 0.0047 16.4 0.1 1.2 1 0 0 1 1 1 1 AAA-like domain Septin PF00735.13 EAU80922.1 - 0.0095 14.9 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_22 PF13401.1 EAU80922.1 - 0.017 15.3 0.2 0.049 13.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAU80922.1 - 0.017 15.1 0.3 0.067 13.1 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 EAU80922.1 - 0.023 14.8 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EAU80922.1 - 0.03 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EAU80922.1 - 0.082 13.2 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAU80922.1 - 0.085 12.4 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EAU80922.1 - 0.14 11.2 0.8 0.57 9.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin DUF4381 PF14316.1 EAU80923.2 - 0.06 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) WD40 PF00400.27 EAU80927.2 - 1.9e-98 319.1 35.7 2.1e-13 49.5 0.0 14.9 15 0 0 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 EAU80927.2 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU80927.2 - 1.3e-06 28.5 0.0 3.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU80927.2 - 0.00086 19.4 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SAF_2 PF13144.1 EAU80927.2 - 0.00088 18.8 0.0 22 4.4 0.0 4.8 4 1 0 5 5 5 0 SAF-like NB-ARC PF00931.17 EAU80927.2 - 0.017 13.9 0.0 0.079 11.8 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain Proteasome_A_N PF10584.4 EAU80927.2 - 0.02 14.1 0.0 6.6 6.1 0.0 4.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PIF1 PF05970.9 EAU80927.2 - 0.058 12.3 0.0 0.095 11.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.15 EAU80927.2 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EAU80927.2 - 0.17 12.1 0.0 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Complex1_51K PF01512.12 EAU80928.1 - 1.6e-48 164.2 0.0 2.8e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EAU80928.1 - 2.3e-20 71.4 0.9 2.3e-20 71.4 0.6 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EAU80928.1 - 4.1e-08 32.9 0.0 1.1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Methyltransf_10 PF05971.7 EAU80929.2 - 3.9e-25 88.6 1.0 1.5e-13 50.5 0.0 3.3 2 1 1 3 3 3 3 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EAU80929.2 - 0.0082 16.1 0.0 0.029 14.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAU80929.2 - 0.19 11.0 0.0 0.47 9.8 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase small domain Glyco_hydro_15 PF00723.16 EAU80931.2 - 5.5e-20 71.3 0.0 1.1e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 BTB PF00651.26 EAU80932.2 - 8e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RepB-RCR_reg PF10723.4 EAU80933.2 - 0.16 11.7 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Replication regulatory protein RepB F1F0-ATPsyn_F PF10791.4 EAU80934.1 - 7.4e-25 87.0 0.0 8.8e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Gpi16 PF04113.9 EAU80935.2 - 2.2e-131 438.6 3.9 1.7e-72 244.2 0.6 2.0 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component AAA PF00004.24 EAU80936.2 - 1.7e-83 277.3 0.0 1.3e-40 138.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAU80936.2 - 4e-12 45.7 0.0 0.00047 19.2 0.0 3.4 2 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAU80936.2 - 7.9e-12 45.0 0.1 1e-05 25.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAU80936.2 - 6.8e-11 42.4 0.9 1.3e-05 25.2 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 EAU80936.2 - 1.3e-10 41.4 0.0 0.00041 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAU80936.2 - 2.2e-09 37.5 0.1 0.00041 20.5 0.0 4.6 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAU80936.2 - 9e-09 34.9 0.0 0.00013 21.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAU80936.2 - 8.4e-08 31.5 0.0 0.00015 20.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 EAU80936.2 - 9e-08 32.0 0.0 0.00012 21.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EAU80936.2 - 1.3e-07 31.5 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EAU80936.2 - 1.7e-07 30.8 0.7 0.0004 20.0 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain TIP49 PF06068.8 EAU80936.2 - 2.6e-07 29.6 0.0 0.0053 15.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EAU80936.2 - 6.5e-07 28.9 2.9 0.21 10.9 0.0 4.4 2 2 1 4 4 4 2 AAA domain AAA_17 PF13207.1 EAU80936.2 - 7.5e-06 26.7 0.0 0.00046 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EAU80936.2 - 0.00017 20.8 0.1 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EAU80936.2 - 0.00018 21.1 0.3 0.057 13.0 0.0 3.7 4 0 0 4 4 4 1 NACHT domain RNA_helicase PF00910.17 EAU80936.2 - 0.00021 21.3 0.0 0.051 13.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 EAU80936.2 - 0.00028 20.9 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EAU80936.2 - 0.00049 20.0 0.0 0.088 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DAP3 PF10236.4 EAU80936.2 - 0.0009 18.2 0.0 0.0038 16.2 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.1 EAU80936.2 - 0.0012 18.4 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAU80936.2 - 0.0014 18.9 0.0 0.0053 17.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain Bac_DnaA PF00308.13 EAU80936.2 - 0.0015 18.2 0.0 0.064 12.8 0.0 2.9 2 1 0 2 2 2 1 Bacterial dnaA protein Sigma54_activat PF00158.21 EAU80936.2 - 0.0025 17.3 0.0 0.79 9.1 0.0 3.4 2 1 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EAU80936.2 - 0.0046 16.5 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EAU80936.2 - 0.0047 16.5 0.0 0.92 9.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EAU80936.2 - 0.0061 15.8 0.1 0.42 9.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Arch_ATPase PF01637.13 EAU80936.2 - 0.0066 16.1 0.0 3.2 7.3 0.0 3.9 3 2 2 5 5 5 1 Archaeal ATPase ATP-synt_ab PF00006.20 EAU80936.2 - 0.0099 15.3 0.0 0.15 11.5 0.0 2.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EAU80936.2 - 0.014 15.0 0.1 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EAU80936.2 - 0.016 14.8 0.0 0.84 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EAU80936.2 - 0.018 15.3 0.0 0.42 10.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 EAU80936.2 - 0.045 12.6 0.0 2.7 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.12 EAU80936.2 - 0.051 12.4 0.0 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EAU80936.2 - 0.054 13.0 0.0 0.4 10.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 EAU80936.2 - 0.057 13.1 0.3 2.3 7.9 0.0 3.4 3 2 0 4 4 4 0 NTPase KaiC PF06745.8 EAU80936.2 - 0.076 12.1 0.0 6 5.9 0.0 2.5 2 0 0 2 2 2 0 KaiC AFG1_ATPase PF03969.11 EAU80936.2 - 0.086 11.6 0.0 0.9 8.2 0.0 2.4 3 0 0 3 3 3 0 AFG1-like ATPase DUF815 PF05673.8 EAU80936.2 - 0.13 11.1 0.0 2.8 6.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) ResIII PF04851.10 EAU80936.2 - 0.13 12.0 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit Rad17 PF03215.10 EAU80936.2 - 0.37 9.4 0.3 4.2 5.9 0.0 2.4 2 2 1 3 3 3 0 Rad17 cell cycle checkpoint protein adh_short PF00106.20 EAU80937.1 - 3e-22 79.2 0.2 4.3e-22 78.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU80937.1 - 8.9e-13 48.5 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EAU80937.1 - 1.5e-07 30.9 0.0 2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EAU80937.1 - 3e-06 27.0 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAU80937.1 - 0.00016 21.2 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU80937.1 - 0.0002 21.3 0.1 0.00044 20.3 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EAU80937.1 - 0.017 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EAU80937.1 - 0.045 12.6 0.1 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Kelch_6 PF13964.1 EAU80938.2 - 1.5e-13 50.2 8.0 0.00025 21.0 0.0 7.4 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.1 EAU80938.2 - 4.1e-12 45.7 2.4 0.0097 15.8 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EAU80938.2 - 2.6e-09 37.0 11.8 0.0083 16.2 0.0 7.5 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EAU80938.2 - 2.9e-08 33.3 20.9 0.1 12.3 0.0 7.4 7 2 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EAU80938.2 - 4.5e-06 26.0 2.7 0.23 11.0 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EAU80938.2 - 5.2e-06 26.0 3.0 0.041 13.6 0.0 5.4 5 0 0 5 5 5 1 Kelch motif zf-MYND PF01753.13 EAU80938.2 - 0.00052 19.8 8.6 0.001 18.8 6.0 1.5 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.1 EAU80938.2 - 0.0035 17.2 0.0 0.81 9.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU80938.2 - 0.011 15.6 0.0 0.42 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Shadoo PF14999.1 EAU80938.2 - 0.027 14.3 7.4 0.068 13.0 5.1 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective NACHT PF05729.7 EAU80940.1 - 7.9e-10 38.6 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU80940.1 - 4.1e-07 30.1 0.3 2.3e-06 27.7 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAU80940.1 - 0.00067 18.6 0.0 0.002 17.0 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 EAU80940.1 - 0.00069 19.7 0.0 0.0024 17.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU80940.1 - 0.0019 19.0 0.1 0.0076 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EAU80940.1 - 0.0056 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EAU80940.1 - 0.06 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EAU80940.1 - 0.1 12.7 0.2 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EAU80940.1 - 0.15 12.2 2.6 1 9.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FAD_binding_3 PF01494.14 EAU80941.1 - 2.8e-10 39.7 0.0 0.0016 17.5 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_9 PF13454.1 EAU80941.1 - 0.0016 18.2 0.4 0.021 14.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAU80941.1 - 0.012 15.6 0.1 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU80941.1 - 0.029 13.2 1.1 0.27 10.0 0.1 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EAU80941.1 - 0.069 11.7 0.2 2.7 6.5 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase DSPc PF00782.15 EAU80942.1 - 1.3e-31 108.9 0.0 1.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EAU80942.1 - 0.00033 19.6 0.0 0.00035 19.5 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EAU80942.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SE PF08491.5 EAU80943.1 - 1.4e-82 276.6 0.0 1.9e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EAU80943.1 - 1.9e-06 27.0 0.0 1.8e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU80943.1 - 1.9e-05 23.9 1.5 0.0012 17.9 1.1 2.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EAU80943.1 - 2.7e-05 23.2 0.2 0.00027 19.9 0.1 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EAU80943.1 - 9.1e-05 21.2 0.2 0.0012 17.5 0.3 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Shikimate_DH PF01488.15 EAU80943.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EAU80943.1 - 0.0027 17.6 0.1 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU80943.1 - 0.0035 17.3 0.5 0.007 16.3 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU80943.1 - 0.01 14.7 0.9 0.017 14.0 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EAU80943.1 - 0.037 14.0 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EAU80943.1 - 0.045 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EAU80943.1 - 0.053 13.2 0.3 0.49 10.1 0.0 2.4 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EAU80943.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EAU80943.1 - 0.13 11.7 0.1 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EAU80943.1 - 0.14 11.0 0.2 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase GIDA PF01134.17 EAU80943.1 - 0.14 10.9 1.5 0.12 11.1 0.3 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EAU80943.1 - 0.15 11.7 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Glyco_hydro_61 PF03443.9 EAU80944.1 - 1.6e-38 132.7 0.0 2.2e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_2_C PF02836.12 EAU80945.1 - 1.1e-05 24.5 0.0 1.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EAU80945.1 - 4.1e-05 23.1 0.0 0.00033 20.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EAU80945.1 - 0.00039 20.8 0.0 0.0011 19.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Peptidase_S8 PF00082.17 EAU80946.2 - 7.8e-24 84.2 7.5 1.3e-23 83.5 5.2 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAU80946.2 - 9.1e-05 22.9 0.0 0.00018 21.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DLH PF01738.13 EAU80947.2 - 1.2e-19 70.4 0.1 1.6e-14 53.7 0.1 2.0 1 1 1 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU80947.2 - 8.3e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU80947.2 - 0.00018 21.4 0.0 0.5 10.1 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family BNIP3 PF06553.7 EAU80948.1 - 0.031 13.6 0.9 0.031 13.6 0.6 1.7 2 0 0 2 2 2 0 BNIP3 DUF3209 PF11483.3 EAU80948.1 - 0.054 13.8 0.3 0.46 10.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) F-box PF00646.28 EAU80949.2 - 1.1 8.9 6.4 0.27 10.9 1.2 2.5 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EAU80949.2 - 5.2 6.8 9.8 27 4.5 0.3 4.5 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) EZH2_WD-Binding PF11616.3 EAU80950.2 - 0.073 12.9 0.4 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 WD repeat binding protein EZH2 WD40 PF00400.27 EAU80951.2 - 1.2e-50 167.6 10.6 9.4e-14 50.6 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat NACHT PF05729.7 EAU80951.2 - 2.1e-10 40.4 0.1 7.4e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAU80951.2 - 0.0022 18.0 0.3 0.0075 16.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAU80951.2 - 0.0089 16.8 0.1 0.031 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EAU80951.2 - 0.032 13.9 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EAU80951.2 - 0.034 14.4 0.1 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU80951.2 - 0.034 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAU80951.2 - 0.06 13.5 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 EAU80951.2 - 0.1 12.8 0.3 0.29 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAU80951.2 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.1 EAU80955.2 - 4.4e-16 59.5 0.0 3e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU80955.2 - 5e-09 36.3 0.0 2.4e-05 24.3 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU80955.2 - 5.4e-06 26.2 1.9 2.4 7.9 0.0 4.4 4 0 0 4 4 4 3 FAD-NAD(P)-binding DAO PF01266.19 EAU80955.2 - 8.2e-06 24.9 2.5 0.036 12.9 0.1 3.4 3 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU80955.2 - 2.4e-05 24.2 1.5 0.00013 21.9 0.0 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAU80955.2 - 0.00011 20.8 2.3 0.34 9.3 0.0 3.6 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EAU80955.2 - 0.00018 20.5 0.6 0.0018 17.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EAU80955.2 - 0.00065 18.6 1.3 0.085 11.6 0.0 3.0 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 EAU80955.2 - 0.00083 19.5 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding Pyr_redox PF00070.22 EAU80955.2 - 0.0077 16.6 1.4 1.2 9.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU80955.2 - 0.017 14.2 0.6 0.17 10.9 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Shikimate_DH PF01488.15 EAU80955.2 - 0.026 14.6 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EAU80955.2 - 0.038 13.4 0.0 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EAU80955.2 - 0.072 11.9 2.0 4.1 6.1 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EAU80955.2 - 0.086 12.4 0.9 6.9 6.2 0.0 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EAU80955.2 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DIOX_N PF14226.1 EAU80956.2 - 7.4e-24 84.5 0.0 1.2e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAU80956.2 - 7.7e-20 71.0 0.0 1.2e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribonuclease PF00545.15 EAU80966.2 - 0.0034 17.4 5.2 0.0045 17.0 0.1 2.3 1 1 1 2 2 2 1 ribonuclease Lactamase_B_2 PF12706.2 EAU80968.1 - 5.9e-22 78.1 0.3 8.4e-22 77.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAU80968.1 - 5e-14 52.3 0.4 2.2e-13 50.2 0.3 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAU80968.1 - 0.0056 16.3 7.5 0.066 12.8 4.3 2.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily zf-MYND PF01753.13 EAU80969.2 - 8.9e-11 41.4 5.5 1.6e-10 40.6 3.8 1.4 1 0 0 1 1 1 1 MYND finger DUF4028 PF13220.1 EAU80970.1 - 0.044 13.4 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) DUF3270 PF11674.3 EAU80971.2 - 0.11 12.4 0.3 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Cytotoxic PF09000.5 EAU80971.2 - 0.17 11.9 0.8 0.34 10.9 0.6 1.4 1 0 0 1 1 1 0 Cytotoxic XdhC_CoxI PF02625.11 EAU80971.2 - 0.68 9.6 4.6 0.43 10.2 1.1 2.1 2 0 0 2 2 2 0 XdhC and CoxI family zf-C2H2_4 PF13894.1 EAU80975.2 - 1.9e-09 37.1 47.5 0.15 12.4 0.3 9.0 9 0 0 9 9 9 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU80975.2 - 2.7e-08 33.6 49.7 0.00052 20.2 0.7 8.4 9 0 0 9 9 9 6 Zinc finger, C2H2 type Ribosomal_L35p PF01632.14 EAU80975.2 - 0.00015 21.6 1.4 13 5.7 0.0 5.3 5 0 0 5 5 5 1 Ribosomal protein L35 DUF3505 PF12013.3 EAU80975.2 - 0.042 14.0 25.0 12 6.1 0.0 7.7 6 2 2 9 9 9 0 Protein of unknown function (DUF3505) PGM_PMM_II PF02879.11 EAU80975.2 - 0.078 13.3 0.2 44 4.4 0.0 3.9 3 1 1 4 4 4 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II zf-met PF12874.2 EAU80975.2 - 6 7.2 13.5 0.67 10.2 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EAU80976.2 - 3.9e-07 29.9 27.5 0.2 12.0 0.3 5.2 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU80976.2 - 4e-05 23.7 31.7 0.0051 17.0 1.6 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type IBR PF01485.16 EAU80976.2 - 0.0049 16.7 14.9 1.1 9.1 1.4 4.7 1 1 2 3 3 3 1 IBR domain Ribosomal_L35p PF01632.14 EAU80976.2 - 0.0055 16.5 3.6 0.32 10.9 0.0 3.0 3 0 0 3 3 3 2 Ribosomal protein L35 DUF3505 PF12013.3 EAU80976.2 - 0.0095 16.1 16.9 3.6 7.8 0.1 4.8 3 2 2 5 5 5 3 Protein of unknown function (DUF3505) Toxin_65 PF15543.1 EAU80976.2 - 0.01 15.4 0.0 1.3 8.6 0.0 2.4 1 1 1 2 2 2 0 Putative toxin 65 zf-H2C2_5 PF13909.1 EAU80976.2 - 0.012 15.7 32.4 0.4 11.0 0.7 5.5 5 1 0 5 5 5 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EAU80976.2 - 0.03 14.6 1.3 0.03 14.6 0.9 5.6 6 0 0 6 6 6 0 Zinc-finger double domain zf-IS66 PF13005.2 EAU80976.2 - 0.03 14.2 0.0 0.12 12.3 0.0 2.1 1 0 0 1 1 1 0 zinc-finger binding domain of transposase IS66 His_Phos_1 PF00300.17 EAU80977.2 - 2.1e-16 60.4 0.0 3.7e-16 59.6 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Phosducin PF02114.11 EAU80977.2 - 0.087 11.5 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosducin zf-MYND PF01753.13 EAU80980.2 - 2.3e-09 36.9 9.2 5.8e-09 35.6 6.4 1.7 1 0 0 1 1 1 1 MYND finger SecY PF00344.15 EAU80981.2 - 6.2e-94 314.7 9.4 7.8e-94 314.4 6.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EAU80981.2 - 1.8e-19 68.9 0.2 6e-19 67.2 0.1 2.0 2 0 0 2 2 2 1 Plug domain of Sec61p ApoLp-III PF07464.6 EAU80982.1 - 0.0032 17.4 0.1 0.038 14.0 0.0 1.9 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) NIT PF08376.5 EAU80982.1 - 0.039 13.4 0.1 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing Apolipoprotein PF01442.13 EAU80982.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain COG2 PF06148.6 EAU80982.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.3 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 EAU80982.1 - 0.42 9.7 2.8 1.1 8.3 1.7 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein COX15-CtaA PF02628.10 EAU80984.2 - 0.075 11.8 8.5 0.0076 15.1 2.7 1.6 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein DUF1129 PF06570.6 EAU80984.2 - 0.17 11.1 0.1 0.17 11.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) AKAP7_NLS PF10469.4 EAU80986.2 - 2.6e-16 59.9 0.0 5.6e-08 32.7 0.0 3.1 3 1 0 3 3 3 2 AKAP7 2'5' RNA ligase-like domain Ras PF00071.17 EAU80987.2 - 1.2e-25 89.8 0.0 1.1e-18 67.1 0.0 3.0 2 1 1 3 3 3 3 Ras family Miro PF08477.8 EAU80987.2 - 1.8e-07 31.6 0.0 5.4e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EAU80988.2 - 1.7e-20 73.0 0.0 7e-15 54.7 0.0 2.5 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EAU80988.2 - 5.3e-10 39.8 0.0 1.7e-07 31.7 0.0 2.7 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EAU80988.2 - 0.0034 16.5 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EAU80988.2 - 0.0056 16.6 0.1 4 7.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EAU80988.2 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 EAU80988.2 - 0.016 15.1 0.1 0.044 13.7 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.16 EAU80988.2 - 0.022 14.0 0.0 0.3 10.2 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU80988.2 - 0.036 13.2 0.0 0.38 9.8 0.0 2.2 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EAU80988.2 - 0.059 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Chor_lyase PF04345.8 EAU80988.2 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Chorismate lyase Ras PF00071.17 EAU80990.2 - 2.7e-55 186.1 0.0 3.1e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU80990.2 - 1.3e-15 57.9 0.0 1.7e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU80990.2 - 9.2e-07 28.2 0.0 1.5e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAU80990.2 - 0.0026 17.0 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EAU80990.2 - 0.053 12.6 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EAU80990.2 - 0.11 11.9 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EAU80991.2 - 2.8e-18 65.8 0.0 5.3e-07 29.1 0.0 3.1 2 1 1 3 3 3 3 Ras family Miro PF08477.8 EAU80991.2 - 0.00012 22.5 0.0 0.00047 20.6 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EAU80991.2 - 0.076 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAU80991.2 - 0.16 11.8 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EAU80993.2 - 6.7e-06 25.5 0.0 9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Sugar_tr PF00083.19 EAU80994.2 - 4.5e-44 150.7 11.5 2.3e-25 89.1 0.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAU80994.2 - 6.9e-24 84.2 17.7 2.5e-15 56.0 1.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EAU80995.1 - 0.00026 20.6 0.3 0.00091 18.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EAU80995.1 - 0.17 12.0 0.6 37 4.8 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.2 EAU80995.1 - 1.8 8.2 5.7 6.1 6.5 0.2 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) DUF1996 PF09362.5 EAU80996.2 - 7.5e-68 228.6 0.0 9.8e-68 228.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EAU80997.2 - 7.6e-64 215.5 0.0 7.5e-63 212.3 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) GTP_CH_N PF12471.3 EAU81000.2 - 4.7e-90 300.4 0.0 6.4e-90 300.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EAU81000.2 - 3.5e-14 52.3 0.0 5.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II HTH_10 PF04967.7 EAU81000.2 - 0.043 13.4 0.0 0.62 9.6 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain GntR PF00392.16 EAU81000.2 - 0.11 11.9 0.1 33 4.0 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family BCA_ABC_TP_C PF12399.3 EAU81003.2 - 0.17 11.6 0.2 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Apolipoprotein PF01442.13 EAU81004.1 - 0.028 13.9 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 EAU81004.1 - 0.06 13.3 0.0 2.2 8.2 0.0 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HsbA PF12296.3 EAU81004.1 - 0.19 11.5 1.1 0.98 9.2 0.7 1.9 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Ribonuclease_3 PF00636.21 EAU81005.1 - 2.7e-37 127.6 0.0 2.2e-17 63.5 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EAU81005.1 - 2e-21 76.3 0.0 4.3e-09 36.3 0.0 4.4 4 0 0 4 4 4 4 Ribonuclease-III-like DEAD PF00270.24 EAU81005.1 - 8.5e-19 67.6 0.0 1.7e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU81005.1 - 5.7e-13 48.5 0.0 1.6e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EAU81005.1 - 1.8e-11 43.6 0.0 5.2e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 EAU81005.1 - 5.6e-11 42.5 0.0 2.2e-10 40.6 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-MYND PF01753.13 EAU81006.2 - 7.9e-10 38.4 8.7 1.8e-09 37.3 6.0 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EAU81007.2 - 3e-11 42.9 6.5 5.7e-11 42.0 4.5 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU81007.2 - 0.042 13.1 2.5 0.12 11.6 1.8 1.8 1 0 0 1 1 1 0 Life-span regulatory factor LRRNT PF01462.13 EAU81007.2 - 0.13 11.8 2.6 4 7.0 0.5 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Meleagrin PF08189.6 EAU81007.2 - 0.22 10.9 3.6 0.47 9.9 2.5 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family Baculo_PEP_C PF04513.7 EAU81008.1 - 0.21 11.4 3.6 0.18 11.5 1.2 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus H_lectin PF09458.5 EAU81009.1 - 1.4e-25 88.7 4.9 3.4e-11 42.6 0.1 3.6 4 0 0 4 4 4 3 H-type lectin domain NT-C2 PF10358.4 EAU81009.1 - 0.026 14.0 0.0 0.051 13.0 0.0 1.4 1 1 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3936 PF13072.1 EAU81009.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) zf-MYND PF01753.13 EAU81010.1 - 4.1e-10 39.3 5.6 7.3e-10 38.5 3.9 1.4 1 0 0 1 1 1 1 MYND finger CENP-B_dimeris PF09026.5 EAU81012.2 - 0.055 13.7 3.4 0.079 13.2 0.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RNA_pol_Rpb1_R PF05001.8 EAU81013.1 - 4.8 7.5 9.3 0.25 11.5 1.9 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat zf-CCHC_6 PF15288.1 EAU81017.2 - 0.088 12.4 0.7 0.088 12.4 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle YhfH PF14149.1 EAU81017.2 - 0.2 11.4 5.3 0.4 10.5 3.7 1.5 1 0 0 1 1 1 0 YhfH-like protein Zn_Tnp_IS1595 PF12760.2 EAU81017.2 - 0.26 11.1 8.9 0.4 10.5 6.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EAU81017.2 - 0.47 10.4 4.2 3.4 7.6 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 EAU81017.2 - 0.78 9.1 4.5 1.8 7.9 0.3 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain zf-CCHC PF00098.18 EAU81017.2 - 7.1 6.7 12.5 0.15 12.0 1.8 2.8 1 1 2 3 3 3 0 Zinc knuckle PCI PF01399.22 EAU81018.2 - 1.5e-16 60.5 0.0 4.8e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EAU81018.2 - 0.00091 18.8 5.4 0.16 11.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU81018.2 - 0.012 15.3 7.7 1.9 8.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.4 EAU81018.2 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 DDRGK domain TPR_14 PF13428.1 EAU81018.2 - 0.028 15.0 8.4 23 5.9 0.2 5.2 4 2 1 5 5 5 0 Tetratricopeptide repeat DDE_Tnp_1_assoc PF13808.1 EAU81018.2 - 0.064 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-associated HNH_2 PF13391.1 EAU81019.1 - 3e-05 23.7 0.1 6.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Helitron_like_N PF14214.1 EAU81021.2 - 5.5e-11 42.5 0.0 7.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus F-box PF00646.28 EAU81025.2 - 2.5e-06 26.9 0.0 6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU81025.2 - 0.034 13.8 0.1 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like Cyclin_N PF00134.18 EAU81026.2 - 4.7e-11 42.3 0.0 6.7e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EAU81026.2 - 0.092 13.1 0.1 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin Fungal_trans PF04082.13 EAU81027.2 - 5.2e-17 61.5 0.1 1.1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GLTP PF08718.6 EAU81028.2 - 1e-29 103.4 0.0 1.3e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ecl1 PF12855.2 EAU81029.2 - 0.08 12.2 3.7 0.28 10.5 0.2 2.6 2 0 0 2 2 2 0 Life-span regulatory factor CCD PF07860.6 EAU81029.2 - 0.99 8.8 0.0 0.99 8.8 0.0 2.7 3 0 0 3 3 3 0 WisP family C-Terminal Region Pertussis_S1 PF02917.9 EAU81030.1 - 0.038 13.5 0.1 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Pheromone PF08015.6 EAU81030.1 - 0.67 10.8 2.8 8.7 7.2 0.2 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone Chs3p PF12271.3 EAU81033.2 - 2e-21 76.2 3.8 2.3e-21 76.0 2.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit BPD_transp_2 PF02653.11 EAU81033.2 - 0.025 13.5 0.7 0.025 13.5 0.5 1.9 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component Apq12 PF12716.2 EAU81033.2 - 0.17 11.6 14.9 0.48 10.1 2.9 2.7 3 0 0 3 3 3 0 Nuclear pore assembly and biogenesis DUF4149 PF13664.1 EAU81033.2 - 2.7 8.1 7.9 2.4 8.2 4.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Abi PF02517.11 EAU81033.2 - 6.3 7.0 6.6 3.1 7.9 1.2 2.1 1 1 1 2 2 2 0 CAAX protease self-immunity Laps PF10169.4 EAU81039.1 - 0.025 14.8 1.7 0.038 14.2 1.2 1.3 1 0 0 1 1 1 0 Learning-associated protein Syntaxin-6_N PF09177.6 EAU81039.1 - 0.38 11.1 2.5 1.1 9.7 0.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal NfeD PF01957.13 EAU81040.2 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Cyt-b5 PF00173.23 EAU81041.1 - 4.8e-11 42.3 0.1 7e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Serglycin PF04360.7 EAU81042.1 - 0.32 10.7 5.1 0.41 10.3 3.5 1.3 1 0 0 1 1 1 0 Serglycin DUF2457 PF10446.4 EAU81042.1 - 2 7.0 10.1 2.2 6.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CAF1-p150_C2 PF15539.1 EAU81042.1 - 6 5.9 7.1 7.7 5.5 4.9 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term DJ-1_PfpI PF01965.19 EAU81043.1 - 4.4e-24 84.6 0.0 2.5e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EAU81043.1 - 7.1e-05 22.2 0.1 0.00022 20.6 0.1 1.9 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family GATase_3 PF07685.9 EAU81043.1 - 0.039 13.5 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EAU81043.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase zf-MYND PF01753.13 EAU81044.2 - 3.4e-10 39.6 7.0 3.4e-10 39.6 4.8 2.2 2 0 0 2 2 2 1 MYND finger Death PF00531.17 EAU81044.2 - 0.11 12.2 0.0 1.2 8.9 0.0 2.6 3 0 0 3 3 3 0 Death domain ThiF PF00899.16 EAU81046.2 - 4.2e-30 104.3 0.0 4.2e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EAU81046.2 - 0.0049 16.9 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FCD PF07729.7 EAU81048.1 - 0.024 14.9 0.7 0.056 13.7 0.1 1.8 2 0 0 2 2 2 0 FCD domain DUF2982 PF11201.3 EAU81048.1 - 0.15 11.4 0.0 0.83 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2982) DUF4581 PF15167.1 EAU81049.2 - 0.032 14.1 1.0 0.042 13.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) LEAP-2 PF07359.6 EAU81049.2 - 0.31 10.6 1.7 0.75 9.4 1.2 1.7 1 1 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Toxin_56 PF15534.1 EAU81050.2 - 0.034 14.6 0.7 0.071 13.6 0.5 1.5 1 0 0 1 1 1 0 Putative toxin 56 Sugar_tr PF00083.19 EAU81051.1 - 2.6e-36 125.1 21.4 3.5e-36 124.7 14.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU81051.1 - 4.7e-35 120.9 27.8 4.7e-35 120.9 19.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 EAU81051.1 - 0.0001 20.9 18.6 0.0028 16.2 3.8 2.5 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EAU81051.1 - 0.22 11.3 6.1 0.43 10.4 0.0 3.1 3 0 0 3 3 3 0 MFS_1 like family RPN7 PF10602.4 EAU81052.1 - 1.4e-56 190.6 0.5 2e-56 190.1 0.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EAU81052.1 - 2e-16 60.2 0.0 9.7e-16 57.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain SR-25 PF10500.4 EAU81052.1 - 0.0032 16.9 0.9 0.0049 16.3 0.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TPR_14 PF13428.1 EAU81052.1 - 0.046 14.3 0.8 8.8 7.2 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 EAU81052.1 - 0.067 12.2 0.6 0.13 11.2 0.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU81052.1 - 0.18 11.7 4.9 1.5 8.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DDHD PF02862.12 EAU81056.2 - 0.36 10.6 9.2 0.76 9.5 6.4 1.5 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.3 EAU81056.2 - 2.2 7.6 33.8 4 6.7 23.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APH PF01636.18 EAU81059.1 - 0.024 14.3 0.0 0.088 12.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF594 PF04578.8 EAU81060.2 - 0.029 13.7 0.1 0.055 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF594 LBP_BPI_CETP PF01273.20 EAU81061.1 - 0.032 13.5 0.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain Glyoxal_oxid_N PF07250.6 EAU81062.2 - 1.6e-43 148.5 0.0 1.9e-41 141.7 0.0 2.6 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EAU81062.2 - 1.6e-22 79.4 0.0 3.1e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EAU81062.2 - 0.00011 21.8 0.0 0.27 11.0 0.0 2.8 2 0 0 2 2 2 2 Galactose oxidase, central domain LAM_C PF12544.3 EAU81064.1 - 0.47 10.5 3.1 0.64 10.0 0.0 2.1 1 1 0 2 2 2 0 Lysine-2,3-aminomutase NAD_binding_10 PF13460.1 EAU81065.2 - 1.6e-15 57.5 0.0 5.9e-15 55.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAU81065.2 - 8.5e-05 21.9 0.4 0.00023 20.4 0.3 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EAU81065.2 - 0.0012 18.3 0.0 0.61 9.4 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family BNR PF02012.15 EAU81066.2 - 1.2e-11 42.5 33.6 1.2 9.1 0.0 11.1 10 0 0 10 10 10 8 BNR/Asp-box repeat PSII_BNR PF14870.1 EAU81066.2 - 0.0018 17.3 2.5 2.2 7.1 0.0 4.3 4 2 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.10 EAU81066.2 - 0.0052 16.4 0.0 0.85 9.3 0.0 2.5 2 0 0 2 2 2 2 Iron dependent repressor, metal binding and dimerisation domain APH PF01636.18 EAU81068.2 - 0.0014 18.3 0.0 0.022 14.4 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAU81068.2 - 0.012 14.7 0.0 0.037 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.9 EAU81068.2 - 0.018 14.1 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF155 PF02582.9 EAU81069.2 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Pkinase PF00069.20 EAU81070.1 - 4.6e-05 22.7 0.0 9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU81070.1 - 0.00054 19.7 0.1 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Gag_p12 PF01141.13 EAU81071.1 - 0.04 14.0 1.9 2.3 8.4 0.4 2.4 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 zf-MYND PF01753.13 EAU81072.2 - 3.9e-08 33.0 9.3 7.9e-08 32.0 6.4 1.5 1 0 0 1 1 1 1 MYND finger nsp8 PF08717.5 EAU81072.2 - 0.15 11.6 0.0 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 nsp8 replicase MMPL PF03176.10 EAU81074.2 - 0.93 8.1 2.9 0.56 8.8 0.9 1.4 2 0 0 2 2 2 0 MMPL family Asp PF00026.18 EAU81075.2 - 2e-08 33.8 0.0 2.8e-06 26.8 0.0 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Cellulase PF00150.13 EAU81078.2 - 7.8e-09 35.1 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pheromone PF08015.6 EAU81081.1 - 1.3 9.8 4.5 4.5 8.1 0.3 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF4218 PF13960.1 EAU81083.2 - 0.016 14.6 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) IncA PF04156.9 EAU81085.1 - 2e-05 24.2 1.8 3.7e-05 23.3 1.3 1.4 1 0 0 1 1 1 1 IncA protein ORF6C PF10552.4 EAU81085.1 - 0.00035 20.2 1.3 0.0053 16.4 0.4 2.3 2 0 0 2 2 2 1 ORF6C domain Myosin_tail_1 PF01576.14 EAU81085.1 - 0.00052 17.8 1.7 0.00071 17.4 1.2 1.1 1 0 0 1 1 1 1 Myosin tail Prefoldin_2 PF01920.15 EAU81085.1 - 0.00097 18.8 4.6 0.0036 17.0 1.5 2.2 2 0 0 2 2 2 1 Prefoldin subunit Atg14 PF10186.4 EAU81085.1 - 0.001 18.0 0.5 0.0015 17.5 0.4 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CALCOCO1 PF07888.6 EAU81085.1 - 0.0012 17.2 1.4 0.0012 17.2 1.0 1.3 2 0 0 2 2 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like TSC22 PF01166.13 EAU81085.1 - 0.0015 18.4 10.9 0.11 12.4 3.5 3.2 3 0 0 3 3 3 1 TSC-22/dip/bun family Transposase_22 PF02994.9 EAU81085.1 - 0.0025 16.3 2.9 0.0036 15.8 2.0 1.2 1 0 0 1 1 1 1 L1 transposable element DivIVA PF05103.8 EAU81085.1 - 0.0026 17.8 0.8 0.29 11.1 0.4 2.3 2 0 0 2 2 2 1 DivIVA protein DUF2353 PF09789.4 EAU81085.1 - 0.0031 16.8 1.9 0.0048 16.2 1.3 1.4 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CASP_C PF08172.7 EAU81085.1 - 0.0033 16.4 0.4 0.0064 15.5 0.2 1.5 1 0 0 1 1 1 1 CASP C terminal bZIP_1 PF00170.16 EAU81085.1 - 0.0033 17.3 8.0 0.021 14.7 2.2 2.7 3 0 0 3 3 2 1 bZIP transcription factor DUF607 PF04678.8 EAU81085.1 - 0.0038 17.1 0.6 0.0071 16.2 0.2 1.7 2 0 0 2 2 1 1 Protein of unknown function, DUF607 CCDC-167 PF15188.1 EAU81085.1 - 0.0047 16.8 7.3 0.059 13.3 2.2 2.4 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 V_ATPase_I PF01496.14 EAU81085.1 - 0.0049 14.7 0.1 0.0056 14.6 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Bap31 PF05529.7 EAU81085.1 - 0.0066 15.9 0.2 0.0066 15.9 0.1 1.5 2 0 0 2 2 1 1 B-cell receptor-associated protein 31-like FlaC_arch PF05377.6 EAU81085.1 - 0.0068 16.2 5.0 0.012 15.5 1.2 2.2 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Tektin PF03148.9 EAU81085.1 - 0.0075 14.8 1.4 0.011 14.3 0.9 1.4 1 1 0 1 1 1 1 Tektin family DUF972 PF06156.8 EAU81085.1 - 0.0076 16.5 3.8 0.1 12.9 2.6 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 EAU81085.1 - 0.009 16.0 2.9 0.12 12.3 2.6 2.0 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain CCDC155 PF14662.1 EAU81085.1 - 0.01 15.4 4.3 0.027 14.0 3.0 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 BicD PF09730.4 EAU81085.1 - 0.011 14.0 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Filament PF00038.16 EAU81085.1 - 0.012 15.1 0.8 0.02 14.3 0.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein Tropomyosin PF00261.15 EAU81085.1 - 0.014 14.4 5.5 0.024 13.7 3.8 1.3 1 0 0 1 1 1 0 Tropomyosin Macoilin PF09726.4 EAU81085.1 - 0.015 13.6 5.5 0.012 13.9 3.0 1.4 1 1 0 1 1 1 0 Transmembrane protein CENP-F_leu_zip PF10473.4 EAU81085.1 - 0.017 14.9 7.9 0.21 11.4 5.5 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 EAU81085.1 - 0.035 14.5 1.7 0.04 14.3 0.2 1.8 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 EAU81085.1 - 0.042 13.7 0.5 0.081 12.8 0.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EAU81085.1 - 0.058 12.4 0.5 0.077 12.0 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 EAU81085.1 - 0.06 10.6 0.4 0.075 10.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC144C PF14915.1 EAU81085.1 - 0.069 12.0 4.4 0.075 11.9 0.8 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region AAA_13 PF13166.1 EAU81085.1 - 0.079 11.4 0.5 0.16 10.4 0.4 1.4 1 1 0 1 1 1 0 AAA domain TBPIP PF07106.8 EAU81085.1 - 0.089 12.3 3.4 0.25 10.8 2.4 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1515 PF07439.6 EAU81085.1 - 0.12 12.1 1.3 0.25 11.1 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DivIC PF04977.10 EAU81085.1 - 0.13 11.7 2.7 0.21 11.1 1.6 1.6 1 1 0 1 1 1 0 Septum formation initiator HOOK PF05622.7 EAU81085.1 - 0.13 10.0 7.2 0.079 10.7 3.5 1.5 1 1 0 1 1 1 0 HOOK protein Prefoldin PF02996.12 EAU81085.1 - 0.13 11.8 0.8 1.2 8.7 0.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 EAU81085.1 - 0.14 12.6 1.0 0.78 10.1 0.7 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EAU81085.1 - 0.15 11.9 5.0 0.55 10.0 3.2 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4446 PF14584.1 EAU81085.1 - 0.15 11.9 2.2 0.23 11.2 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) BLOC1_2 PF10046.4 EAU81085.1 - 0.16 12.1 2.5 1.4 9.1 0.2 2.7 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 EAU81085.1 - 0.17 11.7 4.5 0.31 10.8 2.7 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EAU81085.1 - 0.21 11.4 10.0 0.38 10.6 5.5 2.2 2 1 0 2 2 2 0 Tropomyosin like THOC7 PF05615.8 EAU81085.1 - 0.22 11.8 6.1 3.6 7.8 1.0 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Spc7 PF08317.6 EAU81085.1 - 0.22 10.1 3.0 0.24 10.0 1.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Cep57_CLD_2 PF14197.1 EAU81085.1 - 0.34 10.8 6.6 1.2 9.0 1.1 2.7 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 Ax_dynein_light PF10211.4 EAU81085.1 - 0.38 10.5 9.0 1.8 8.3 5.7 2.1 1 1 0 1 1 1 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.7 EAU81085.1 - 0.38 10.4 4.0 0.79 9.4 2.0 2.1 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.6 EAU81085.1 - 0.4 9.1 3.6 0.76 8.2 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Striatin PF08232.7 EAU81085.1 - 0.41 10.9 5.7 1 9.6 3.7 1.8 1 1 0 1 1 1 0 Striatin family DUF904 PF06005.7 EAU81085.1 - 0.84 9.9 7.2 1.2 9.5 4.3 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF904) GAS PF13851.1 EAU81085.1 - 0.87 8.7 6.5 2.5 7.2 4.5 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MerR-DNA-bind PF09278.6 EAU81085.1 - 0.91 9.9 4.6 0.86 10.0 1.0 2.4 2 0 0 2 2 2 0 MerR, DNA binding Med21 PF11221.3 EAU81085.1 - 0.95 9.4 6.9 0.28 11.1 2.6 1.7 2 0 0 2 2 1 0 Subunit 21 of Mediator complex Mnd1 PF03962.10 EAU81085.1 - 1 8.9 4.0 2.7 7.6 2.8 1.6 1 1 1 2 2 2 0 Mnd1 family Sipho_Gp157 PF05565.6 EAU81085.1 - 1.4 8.4 5.1 2 8.0 1.7 2.0 1 1 0 2 2 2 0 Siphovirus Gp157 Uds1 PF15456.1 EAU81085.1 - 1.9 8.4 8.1 31 4.5 5.6 2.4 1 1 0 1 1 1 0 Up-regulated During Septation bZIP_2 PF07716.10 EAU81085.1 - 2.2 8.1 9.8 0.34 10.7 2.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper HAP1_N PF04849.8 EAU81085.1 - 2.2 7.1 7.8 8.6 5.2 5.3 1.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region ERM PF00769.14 EAU81085.1 - 2.3 7.7 9.8 0.87 9.0 3.9 1.7 1 1 0 2 2 2 0 Ezrin/radixin/moesin family GrpE PF01025.14 EAU81085.1 - 2.4 7.6 6.7 1.6 8.2 2.4 2.0 1 1 1 2 2 2 0 GrpE Med9 PF07544.8 EAU81085.1 - 3.1 7.5 8.6 9 6.1 0.5 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 EAU81085.1 - 4.4 7.2 9.8 3.8 7.4 4.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 EAU81085.1 - 5 6.8 8.4 24 4.6 5.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Toxin_52 PF15605.1 EAU81092.1 - 0.013 15.3 0.1 0.4 10.5 0.0 2.1 1 1 1 2 2 2 0 Putative toxin 52 DUF1394 PF07159.7 EAU81092.1 - 0.024 13.7 0.0 0.025 13.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) DUF3829 PF12889.2 EAU81092.1 - 0.082 12.0 0.1 0.096 11.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2746 PF10874.3 EAU81092.1 - 0.096 12.8 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) LTXXQ PF07813.7 EAU81097.2 - 5.3 7.5 9.3 15 6.1 0.5 3.0 3 0 0 3 3 3 0 LTXXQ motif family protein HMG_box_2 PF09011.5 EAU81105.1 - 1.5e-05 25.2 0.2 6.2e-05 23.2 0.1 2.1 1 0 0 1 1 1 1 HMG-box domain FlxA PF14282.1 EAU81106.1 - 0.0057 16.5 1.1 0.0057 16.5 0.8 2.6 2 1 0 2 2 2 1 FlxA-like protein THOC7 PF05615.8 EAU81108.1 - 0.0045 17.2 0.1 0.0054 17.0 0.1 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 APG17 PF04108.7 EAU81108.1 - 0.025 13.4 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 SH2_2 PF14633.1 EAU81111.2 - 1.6e-33 115.6 0.9 2.2e-33 115.2 0.7 1.2 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EAU81111.2 - 1.5e-08 34.5 1.2 2.7e-08 33.7 0.7 1.5 1 1 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.19 EAU81111.2 - 0.00023 20.9 0.0 0.0007 19.3 0.0 1.7 2 0 0 2 2 2 1 SH2 domain Arrestin_N PF00339.24 EAU81111.2 - 0.025 14.3 0.4 0.038 13.8 0.3 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain SH2_2 PF14633.1 EAU81112.2 - 3.7e-17 62.1 0.3 4.4e-16 58.6 0.2 2.0 1 1 0 1 1 1 1 SH2 domain CTD PF12815.2 EAU81112.2 - 0.033 14.6 15.4 0.057 13.8 10.7 1.3 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Laminin_I PF06008.9 EAU81113.2 - 0.037 13.3 17.6 0.011 15.0 9.5 2.0 2 1 0 2 2 2 0 Laminin Domain I Syntaxin-6_N PF09177.6 EAU81113.2 - 0.049 14.0 11.6 0.7 10.3 0.2 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF1521 PF07481.6 EAU81113.2 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) NPV_P10 PF05531.7 EAU81113.2 - 0.08 13.1 0.4 0.08 13.1 0.3 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.6 EAU81113.2 - 0.099 10.1 5.1 0.16 9.4 3.6 1.3 1 0 0 1 1 1 0 Prominin Bacillus_HBL PF05791.6 EAU81113.2 - 0.13 11.6 8.2 9.7 5.5 5.3 2.3 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) RTBV_P46 PF06216.6 EAU81113.2 - 0.14 10.9 4.1 0.17 10.6 2.4 1.4 1 1 0 1 1 1 0 Rice tungro bacilliform virus P46 protein AAA_13 PF13166.1 EAU81113.2 - 0.17 10.3 11.5 0.26 9.6 8.0 1.2 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.11 EAU81113.2 - 0.19 10.3 0.2 0.26 9.8 0.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_PEP_C PF04513.7 EAU81113.2 - 0.21 11.4 2.8 0.27 11.0 0.4 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Utp12 PF04003.7 EAU81113.2 - 0.46 10.4 9.7 1.8 8.5 1.2 4.1 2 1 2 4 4 4 0 Dip2/Utp12 Family DUF1664 PF07889.7 EAU81113.2 - 1.1 9.0 8.4 5.8 6.7 1.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 EAU81113.2 - 1.3 8.4 16.4 0.065 12.6 3.3 2.8 1 1 1 3 3 3 0 Phage minor structural protein GP20 IFT57 PF10498.4 EAU81113.2 - 2.1 7.0 17.1 5.4 5.6 11.9 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.15 EAU81113.2 - 3.2 7.5 15.8 0.26 11.0 2.8 3.3 3 0 0 3 3 3 0 Prefoldin subunit ATG16 PF08614.6 EAU81113.2 - 6.2 6.5 22.3 2.2 8.0 2.8 3.1 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF16 PF01519.11 EAU81113.2 - 7.2 6.8 17.1 37 4.5 4.4 3.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 HAUS-augmin3 PF14932.1 EAU81113.2 - 7.5 5.6 20.8 1.2 8.2 2.2 3.0 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 Sad1_UNC PF07738.8 EAU81114.2 - 4.2e-10 39.5 0.0 0.00011 22.0 0.0 2.3 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal HSBP1 PF06825.7 EAU81114.2 - 0.056 13.0 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 zf-C3HC4 PF00097.20 EAU81115.2 - 0.0025 17.4 6.9 0.0025 17.4 4.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU81115.2 - 0.0093 15.8 5.4 0.027 14.3 3.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EAU81115.2 - 0.071 12.7 11.1 0.081 12.6 3.2 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU81115.2 - 0.076 12.8 8.4 0.047 13.5 4.0 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 EAU81115.2 - 0.14 12.1 10.8 0.039 13.9 4.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU81115.2 - 0.48 10.1 7.5 0.079 12.6 2.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 EAU81115.2 - 2.4 7.9 12.6 0.84 9.4 5.9 2.3 2 1 0 2 2 2 0 zinc-RING finger domain PKD PF00801.15 EAU81116.2 - 0.012 15.3 1.2 0.028 14.1 0.8 1.5 1 0 0 1 1 1 0 PKD domain BACON PF13004.2 EAU81116.2 - 0.16 12.2 0.9 0.35 11.1 0.6 1.5 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal F-box-like PF12937.2 EAU81119.2 - 9.9e-05 21.9 0.0 0.00029 20.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU81120.1 - 0.0011 18.6 3.8 0.0012 18.5 0.1 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EAU81120.1 - 0.0055 16.3 0.1 0.022 14.4 0.1 2.1 1 1 0 1 1 1 1 F-box domain WD40 PF00400.27 EAU81122.2 - 0.00022 21.0 3.5 0.59 10.1 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EAU81122.2 - 0.0016 17.5 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ras PF00071.17 EAU81123.2 - 4e-14 52.3 0.3 5.6e-07 29.0 0.0 2.1 1 1 1 2 2 2 2 Ras family Transposase_21 PF02992.9 EAU81124.2 - 2e-20 72.8 0.0 4.3e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EAU81124.2 - 6e-07 28.9 1.1 1.4e-06 27.7 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SAP PF02037.22 EAU81124.2 - 0.082 12.4 0.2 0.38 10.3 0.1 2.2 1 1 0 1 1 1 0 SAP domain zf-MYND PF01753.13 EAU81127.2 - 5.7e-08 32.4 4.9 1e-07 31.6 3.4 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU81127.2 - 0.0018 17.5 0.9 0.0052 16.0 0.6 1.9 1 0 0 1 1 1 1 Life-span regulatory factor DUF1956 PF09209.6 EAU81127.2 - 0.0024 17.7 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1956) CDC45 PF02724.9 EAU81127.2 - 0.0049 14.9 5.8 0.0067 14.5 4.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF912 PF06024.7 EAU81127.2 - 0.36 10.8 2.6 0.88 9.6 1.8 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) GMC_oxred_N PF00732.14 EAU81128.2 - 1.2e-50 172.3 0.0 1.9e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU81128.2 - 7.9e-31 107.2 0.0 1.8e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU81128.2 - 0.00018 21.4 0.6 0.00058 19.8 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU81128.2 - 0.00093 18.1 0.3 0.0019 17.1 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU81128.2 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU81128.2 - 0.0017 17.2 0.7 0.0028 16.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EAU81128.2 - 0.014 15.4 0.1 0.042 13.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU81128.2 - 0.033 13.2 0.1 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EAU81128.2 - 0.041 13.7 0.1 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fis1_TPR_C PF14853.1 EAU81129.1 - 0.091 12.6 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat HTH_29 PF13551.1 EAU81134.2 - 0.02 15.0 0.2 0.042 13.9 0.1 1.6 2 0 0 2 2 2 0 Winged helix-turn helix PRANC PF09372.5 EAU81136.1 - 0.002 18.0 0.5 0.014 15.3 0.1 2.4 3 0 0 3 3 3 1 PRANC domain F-box PF00646.28 EAU81136.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain LicD PF04991.8 EAU81136.1 - 0.065 13.3 1.4 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 LicD family DUF1470 PF07336.6 EAU81137.1 - 0.18 12.1 4.6 2.3 8.5 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1470) LRR_8 PF13855.1 EAU81139.2 - 0.02 14.6 2.6 0.84 9.4 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat p450 PF00067.17 EAU81142.1 - 2.3e-29 102.2 0.0 1.1e-28 100.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 EAU81143.2 - 6.2e-55 182.8 3.0 1.5e-22 79.0 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein FtsJ PF01728.14 EAU81144.1 - 4.2e-42 144.1 0.0 5.2e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase YccJ PF13993.1 EAU81144.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 YccJ-like protein Y_phosphatase2 PF03162.8 EAU81145.2 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Tyrosine phosphatase family Kelch_6 PF13964.1 EAU81146.1 - 2e-14 53.0 9.1 4e-08 33.1 0.1 6.5 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 EAU81146.1 - 8e-13 48.1 3.4 0.0055 16.8 0.0 6.3 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EAU81146.1 - 1e-09 38.0 18.7 0.052 13.3 0.1 7.3 6 3 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EAU81146.1 - 3.8e-09 36.2 1.2 0.046 13.6 0.0 4.6 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EAU81146.1 - 7.8e-09 34.9 6.7 0.015 14.8 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EAU81146.1 - 3.7e-07 29.6 10.7 0.19 11.5 0.1 6.0 6 0 0 6 6 6 1 Kelch motif zf-MYND PF01753.13 EAU81146.1 - 0.0083 15.9 5.1 0.019 14.8 3.5 1.6 1 0 0 1 1 1 1 MYND finger PPR PF01535.15 EAU81146.1 - 0.054 13.4 0.4 0.054 13.4 0.3 3.7 5 0 0 5 5 5 0 PPR repeat PPR_3 PF13812.1 EAU81146.1 - 0.14 12.5 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 EAU81146.1 - 3 7.8 5.0 1.2 9.1 0.1 2.8 3 0 0 3 3 3 0 PPR repeat family DUF1996 PF09362.5 EAU81147.2 - 4.8e-70 235.8 5.8 2.2e-69 233.6 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU81147.2 - 8.2e-13 47.7 11.9 8.2e-13 47.7 8.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU81147.2 - 0.026 14.5 0.4 0.062 13.3 0.3 1.6 1 0 0 1 1 1 0 Toxin 7 RNA_pol_Rbc25 PF08292.7 EAU81149.1 - 3.3e-33 114.4 0.0 4.3e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EAU81149.1 - 3.4e-23 81.5 0.0 7.1e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.20 EAU81150.2 - 0.00019 20.6 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU81150.2 - 0.017 14.8 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EAU81150.2 - 0.066 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU81151.1 - 0.067 12.3 0.2 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.20 EAU81152.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PMI_typeI PF01238.16 EAU81153.1 - 5.8e-119 397.3 0.0 6.8e-119 397.1 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EAU81153.1 - 0.0056 16.1 0.1 2.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EAU81153.1 - 0.0059 16.2 0.0 5.2 6.7 0.0 3.0 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_1 PF00190.17 EAU81153.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Cupin Aminotran_5 PF00266.14 EAU81154.1 - 9.3e-22 77.2 0.0 1.9e-21 76.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EAU81154.1 - 2.2e-06 26.8 0.0 3.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EAU81154.1 - 7.9e-05 21.8 0.0 0.22 10.4 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EAU81154.1 - 0.0045 15.4 0.0 0.0083 14.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Elong_Iki1 PF10483.4 EAU81154.1 - 0.039 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF368 PF04018.8 EAU81155.2 - 0.24 10.5 6.7 0.049 12.8 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF368) APH PF01636.18 EAU81156.1 - 0.00021 21.1 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family GMC_oxred_N PF00732.14 EAU81159.1 - 1.8e-56 191.5 0.0 2.6e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU81159.1 - 2.1e-36 125.3 0.0 3.7e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAU81159.1 - 0.00013 20.9 1.1 0.044 12.6 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EAU81159.1 - 0.00098 19.2 0.0 0.75 9.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU81159.1 - 0.0048 16.8 1.2 0.019 15.0 0.9 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU81159.1 - 0.0098 14.8 0.7 0.56 9.0 0.6 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU81159.1 - 0.024 13.7 0.1 0.52 9.2 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EAU81159.1 - 0.054 12.3 0.3 0.085 11.7 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EAU81159.1 - 0.061 13.1 0.0 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EAU81161.2 - 2.3e-22 79.1 0.1 5.6e-22 77.8 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF605 PF04652.11 EAU81161.2 - 6.8 5.9 16.6 13 5.0 11.5 1.4 1 0 0 1 1 1 0 Vta1 like Tet_JBP PF12851.2 EAU81164.2 - 2.3e-14 53.0 0.0 3.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF1932 PF09130.6 EAU81167.2 - 0.021 14.5 0.5 0.054 13.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) tRNA-synt_1f PF01921.13 EAU81167.2 - 0.06 12.0 0.1 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) EzrA PF06160.7 EAU81168.1 - 0.0054 14.9 1.9 0.0087 14.3 1.3 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Spc7 PF08317.6 EAU81168.1 - 0.037 12.7 1.0 0.071 11.7 0.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.4 EAU81168.1 - 0.072 11.3 2.4 0.14 10.4 1.6 1.4 1 0 0 1 1 1 0 Transmembrane protein Pro_dh-DNA_bdg PF14850.1 EAU81168.1 - 0.11 12.6 0.0 0.42 10.8 0.1 1.9 2 0 0 2 2 2 0 DNA-binding domain of Proline dehydrogenase DHC_N1 PF08385.7 EAU81168.1 - 0.28 9.5 0.0 0.5 8.6 0.0 1.3 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Baculo_PEP_C PF04513.7 EAU81168.1 - 0.33 10.7 0.6 19 5.0 0.1 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EAU81168.1 - 0.37 10.5 3.5 1.4 8.6 0.7 2.7 2 1 0 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 EAU81168.1 - 1.3 9.2 4.4 2 8.7 0.9 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EAU81168.1 - 2.7 7.7 6.6 0.98 9.2 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) zf-MYND PF01753.13 EAU81170.1 - 0.00017 21.3 11.0 0.00036 20.3 7.6 1.6 1 0 0 1 1 1 1 MYND finger Polyoma_agno PF01736.11 EAU81171.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Polyomavirus agnoprotein zf-Tim10_DDP PF02953.10 EAU81182.2 - 8.9e-13 47.3 1.5 3.7e-11 42.1 1.0 2.1 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Imm6 PF14434.1 EAU81182.2 - 0.016 14.8 0.2 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Immunity protein Imm6 Hep_59 PF07052.6 EAU81182.2 - 0.093 13.0 0.2 0.11 12.8 0.2 1.4 1 1 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Fer4_12 PF13353.1 EAU81182.2 - 0.11 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain Molybdopterin PF00384.17 EAU81183.2 - 6.4e-68 229.4 0.0 3.2e-67 227.1 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EAU81183.2 - 4.9e-20 71.1 0.2 1.5e-19 69.5 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EAU81183.2 - 4.7e-19 67.3 0.1 1.3e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EAU81183.2 - 1.6e-15 56.9 0.0 4.1e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EAU81183.2 - 7.3e-09 35.2 0.7 7.3e-09 35.2 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EAU81183.2 - 0.0017 18.1 0.0 0.077 12.7 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EAU81183.2 - 0.083 12.5 1.1 4 7.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EAU81183.2 - 0.26 11.2 2.4 0.46 10.4 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Menin PF05053.8 EAU81187.1 - 0.64 8.1 2.2 0.9 7.6 1.5 1.1 1 0 0 1 1 1 0 Menin Chitin_synth_2 PF03142.10 EAU81188.2 - 1.8e-241 802.1 0.0 2.5e-241 801.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EAU81188.2 - 6e-143 477.3 0.0 8.8e-143 476.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 EAU81188.2 - 2.8e-17 62.2 1.2 1.1e-16 60.3 0.7 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 EAU81188.2 - 6.9e-16 57.8 0.0 4.7e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EAU81188.2 - 2.1e-13 50.6 0.0 1.1e-09 38.4 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EAU81188.2 - 2.6e-12 46.8 2.9 2.6e-12 46.8 2.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EAU81188.2 - 0.0042 16.7 0.0 0.32 10.6 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAU81188.2 - 0.015 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 PTPA PF03095.10 EAU81189.2 - 1.3e-103 346.3 0.0 2.5e-91 305.9 0.0 2.2 2 1 0 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein SURF6 PF04935.7 EAU81190.1 - 2.9e-38 131.3 41.9 2.9e-38 131.3 29.0 2.5 2 0 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 EAU81190.1 - 3.8e-20 71.7 4.7 3.8e-20 71.7 3.3 5.4 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 Sec62 PF03839.11 EAU81192.2 - 0.86 8.9 5.8 1.4 8.2 4.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.7 EAU81192.2 - 3.4 7.4 15.6 5.1 6.8 10.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EAU81192.2 - 6.9 5.9 15.9 9.9 5.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 EAU81192.2 - 8.1 6.1 8.0 12 5.6 5.6 1.2 1 0 0 1 1 1 0 DDHD domain F-box-like PF12937.2 EAU81193.1 - 2.4e-09 36.7 7.1 6.9e-09 35.2 3.1 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU81193.1 - 0.002 17.7 2.4 0.0033 17.0 0.4 2.3 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EAU81193.1 - 0.16 11.6 1.1 5.6 6.7 0.1 3.5 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EAU81195.1 - 7.8e-07 28.7 1.1 2e-06 27.4 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU81195.1 - 2.7e-05 23.7 0.4 2.7e-05 23.7 0.3 2.1 2 0 0 2 2 2 1 F-box domain Polysacc_synt_4 PF04669.8 EAU81198.2 - 4e-22 78.5 0.8 7.1e-21 74.4 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Myb_DNA-binding PF00249.26 EAU81199.2 - 2e-08 34.1 0.1 3.9e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ETX_MTX2 PF03318.8 EAU81199.2 - 2.2 7.7 8.0 3.4 7.1 5.6 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Glyco_hydro_47 PF01532.15 EAU81201.1 - 4.7e-131 437.5 0.0 5.4e-131 437.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 F-box-like PF12937.2 EAU81202.1 - 0.041 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 F-box-like Innate_immun PF12782.2 EAU81202.1 - 8.3 5.5 7.9 12 4.9 5.5 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Lipase_3 PF01764.20 EAU81203.1 - 1.3e-15 57.2 0.0 3.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_M57 PF12388.3 EAU81203.1 - 0.027 13.7 0.4 0.049 12.9 0.2 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase WD40 PF00400.27 EAU81204.2 - 0.011 15.5 2.2 0.069 13.0 0.0 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Nup160 PF11715.3 EAU81204.2 - 0.018 13.2 0.0 0.021 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3450 PF11932.3 EAU81206.2 - 1.8e-05 24.1 2.9 2.7e-05 23.5 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IncA PF04156.9 EAU81206.2 - 9.2e-05 22.1 4.7 0.00016 21.3 3.3 1.3 1 0 0 1 1 1 1 IncA protein DUF4201 PF13870.1 EAU81206.2 - 0.00053 19.4 6.8 0.00053 19.4 4.7 1.5 2 0 0 2 2 1 1 Domain of unknown function (DUF4201) Cep57_CLD_2 PF14197.1 EAU81206.2 - 0.004 17.0 2.5 0.004 17.0 1.7 2.4 1 1 1 2 2 2 1 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.7 EAU81206.2 - 0.0062 16.2 7.3 0.0062 16.2 5.1 1.7 2 0 0 2 2 1 1 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EAU81206.2 - 0.0079 15.8 2.3 0.015 14.9 0.4 2.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper BLOC1_2 PF10046.4 EAU81206.2 - 0.011 15.8 4.1 0.034 14.2 0.6 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EAU81206.2 - 0.013 15.2 2.2 0.021 14.5 1.5 1.3 1 0 0 1 1 1 0 Laminin Domain II DUF904 PF06005.7 EAU81206.2 - 0.021 15.0 6.9 0.021 15.0 4.8 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF904) GAS PF13851.1 EAU81206.2 - 0.025 13.7 9.1 0.054 12.6 6.3 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.6 EAU81206.2 - 0.035 14.4 4.8 0.73 10.2 1.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CCDC155 PF14662.1 EAU81206.2 - 0.049 13.2 5.8 0.086 12.4 4.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 TMF_TATA_bd PF12325.3 EAU81206.2 - 0.058 13.1 7.0 0.08 12.6 3.9 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EAU81206.2 - 0.059 12.8 8.2 0.071 12.5 1.8 2.5 1 1 1 2 2 2 0 Septum formation initiator Nup54 PF13874.1 EAU81206.2 - 0.082 12.5 6.1 0.15 11.6 4.2 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Vip3A_N PF12495.3 EAU81206.2 - 0.083 12.5 0.4 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal APG6 PF04111.7 EAU81206.2 - 0.084 11.9 5.3 0.17 10.9 3.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 EAU81206.2 - 0.084 12.8 5.5 1.2 9.1 1.0 2.8 1 1 3 4 4 4 0 bZIP transcription factor UPF0242 PF06785.6 EAU81206.2 - 0.1 11.2 3.3 0.15 10.6 2.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF4559 PF15112.1 EAU81206.2 - 0.11 11.6 3.1 0.18 10.9 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Hemagglutinin PF00509.13 EAU81206.2 - 0.12 10.4 2.3 0.17 9.9 1.6 1.1 1 0 0 1 1 1 0 Haemagglutinin Mitofilin PF09731.4 EAU81206.2 - 0.14 10.7 15.3 0.21 10.1 10.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2205 PF10224.4 EAU81206.2 - 0.24 11.0 3.3 1 8.9 1.0 2.5 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF2968 PF11180.3 EAU81206.2 - 0.37 10.1 3.8 0.66 9.3 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Rootletin PF15035.1 EAU81206.2 - 0.81 9.6 10.1 2.5 8.0 7.0 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion NPV_P10 PF05531.7 EAU81206.2 - 0.83 9.9 3.4 15 5.9 1.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 EAU81206.2 - 3.4 8.0 14.9 0.031 14.5 2.3 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EAU81206.2 - 3.7 5.2 3.7 5.4 4.7 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1972 PF09314.6 EAU81207.1 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) TTSSLRR PF12468.3 EAU81209.1 - 0.079 12.5 0.2 0.079 12.5 0.1 3.1 2 1 0 2 2 2 0 Type III secretion system leucine rich repeat protein DUF605 PF04652.11 EAU81209.1 - 0.57 9.5 16.3 0.062 12.6 8.1 1.7 2 0 0 2 2 2 0 Vta1 like Macoilin PF09726.4 EAU81209.1 - 9.1 4.4 16.8 16 3.6 11.6 1.3 1 0 0 1 1 1 0 Transmembrane protein Tet_JBP PF12851.2 EAU81210.2 - 0.022 14.0 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily Pkinase PF00069.20 EAU81211.2 - 0.0001 21.5 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC_membrane PF00664.18 EAU81212.1 - 7.7e-28 97.6 6.7 1.1e-27 97.1 4.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EAU81212.1 - 4e-27 95.1 0.0 7.9e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EAU81212.1 - 4.7e-06 26.7 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAU81212.1 - 0.00072 20.3 0.0 0.0021 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EAU81212.1 - 0.0012 18.8 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAU81212.1 - 0.0013 18.8 0.2 0.013 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAU81212.1 - 0.0021 17.8 0.0 0.01 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EAU81212.1 - 0.0022 17.8 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EAU81212.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAU81212.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EAU81212.1 - 0.043 13.0 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAU81212.1 - 0.085 12.2 0.0 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EAU81212.1 - 0.11 11.1 0.0 0.24 10.0 0.0 1.4 2 0 0 2 2 2 0 G-protein alpha subunit PBP1_TM PF14812.1 EAU81212.1 - 3.6 7.9 10.9 6.8 7.0 4.1 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_membrane PF00664.18 EAU81213.2 - 4.1e-40 137.9 6.3 1.2e-39 136.3 4.4 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EAU81213.2 - 9.5e-10 38.9 0.1 1e-05 25.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.1 EAU81213.2 - 0.00067 20.4 0.0 0.0015 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAU81213.2 - 0.0048 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EAU81213.2 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAU81213.2 - 0.025 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAU81213.2 - 0.027 13.8 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU81213.2 - 0.031 14.5 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAU81213.2 - 0.034 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU81213.2 - 0.039 13.9 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 EAU81213.2 - 0.12 11.8 0.0 0.86 9.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EAU81213.2 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EAU81213.2 - 0.16 11.3 0.2 0.28 10.5 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EAU81213.2 - 0.21 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EAU81217.2 - 0.00017 20.8 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PI-PLC-X PF00388.14 EAU81219.2 - 1.5e-55 186.5 0.0 2.8e-55 185.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EAU81219.2 - 1.4e-36 124.9 0.0 2.6e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EAU81219.2 - 4.2e-11 42.7 0.0 6.5e-09 35.7 0.0 2.4 1 1 1 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EAU81219.2 - 6.6e-08 32.2 0.0 2.7e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 EAU81219.2 - 0.00015 20.8 0.1 0.015 14.5 0.0 3.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EAU81219.2 - 0.00055 20.0 0.8 0.099 12.7 0.0 2.8 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EAU81219.2 - 0.0089 15.6 0.4 0.3 10.7 0.0 3.0 2 1 0 3 3 3 1 EF-hand domain pair EF-hand_10 PF14788.1 EAU81219.2 - 0.061 12.9 0.0 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EAU81219.2 - 0.073 12.9 3.4 5.5 7.1 0.0 4.0 4 1 0 4 4 4 0 EF-hand domain TPR_11 PF13414.1 EAU81220.2 - 3.6e-09 36.1 0.4 7.1e-09 35.1 0.2 1.5 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EAU81220.2 - 0.00052 19.7 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_19 PF14559.1 EAU81220.2 - 0.0024 18.1 0.0 0.0074 16.5 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU81220.2 - 0.014 15.4 0.1 0.034 14.2 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EAU81220.2 - 0.055 13.4 1.4 13 5.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAU81220.2 - 0.11 13.2 0.2 0.11 13.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat FTSW_RODA_SPOVE PF01098.14 EAU81220.2 - 0.16 10.7 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Cell cycle protein Ank PF00023.25 EAU81222.2 - 3.4e-82 266.4 34.3 1e-08 34.5 0.1 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_2 PF12796.2 EAU81222.2 - 2.3e-74 245.8 28.0 5.3e-20 71.5 0.3 7.9 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAU81222.2 - 1.2e-52 170.6 5.0 1.1e-05 25.2 0.0 12.5 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.1 EAU81222.2 - 1.8e-48 162.0 18.4 3.9e-09 36.7 0.1 10.5 2 1 10 12 12 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU81222.2 - 6.1e-47 156.5 29.3 4.7e-09 36.2 0.2 10.6 3 1 7 11 11 11 9 Ankyrin repeats (many copies) UBA_4 PF14555.1 EAU81222.2 - 2.9e-06 26.7 0.1 13 5.4 0.0 7.6 8 0 0 8 8 8 0 UBA-like domain NB-ARC PF00931.17 EAU81222.2 - 0.0043 15.9 0.0 0.0069 15.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NMT1_2 PF13379.1 EAU81222.2 - 0.012 15.0 10.6 0.13 11.6 1.4 4.0 3 1 1 5 5 5 0 NMT1-like family DUF2075 PF09848.4 EAU81222.2 - 0.035 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAU81222.2 - 0.037 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AHH PF14412.1 EAU81222.2 - 0.065 13.2 3.2 74 3.3 0.0 5.9 4 3 3 7 7 7 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Nitro_FeMo-Co PF02579.12 EAU81222.2 - 0.079 13.0 9.7 23 5.1 0.1 5.0 3 2 2 5 5 5 0 Dinitrogenase iron-molybdenum cofactor NACHT PF05729.7 EAU81222.2 - 0.12 12.0 0.0 0.4 10.3 0.0 1.9 1 1 0 1 1 1 0 NACHT domain E3_binding PF02817.12 EAU81222.2 - 0.46 10.1 6.5 23 4.7 0.0 5.8 8 0 0 8 8 8 0 e3 binding domain AMP-binding PF00501.23 EAU81223.1 - 1.4e-95 320.1 0.2 1.8e-95 319.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU81223.1 - 6e-22 78.3 0.2 9.5e-21 74.5 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Crp PF00325.15 EAU81223.1 - 0.0028 17.0 0.0 0.0066 15.9 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, crp family DUF2461 PF09365.5 EAU81224.2 - 7.7e-37 126.7 1.4 2.4e-33 115.3 0.0 3.0 3 0 0 3 3 3 2 Conserved hypothetical protein (DUF2461) CAF-1_p150 PF11600.3 EAU81225.1 - 0.002 17.5 18.1 0.002 17.5 12.6 3.8 5 0 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ank PF00023.25 EAU81226.2 - 6e-69 224.6 29.0 2.7e-08 33.1 0.1 10.6 10 0 0 10 10 10 9 Ankyrin repeat Ank_2 PF12796.2 EAU81226.2 - 2.2e-66 220.1 24.6 1.7e-17 63.5 0.4 7.3 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU81226.2 - 5.5e-43 144.0 19.5 2.1e-09 37.3 0.3 8.5 2 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU81226.2 - 6.9e-39 127.9 2.1 0.00074 19.5 0.0 10.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EAU81226.2 - 1.1e-37 127.7 16.6 4.3e-07 30.2 0.1 8.8 2 1 7 9 9 9 8 Ankyrin repeats (many copies) NB-ARC PF00931.17 EAU81226.2 - 0.00015 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EAU81226.2 - 0.0061 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EAU81226.2 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAU81226.2 - 0.019 15.0 0.0 0.077 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain UBA_4 PF14555.1 EAU81226.2 - 0.054 13.0 0.0 21 4.7 0.0 4.4 6 0 0 6 6 6 0 UBA-like domain cobW PF02492.14 EAU81226.2 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Nitro_FeMo-Co PF02579.12 EAU81226.2 - 1.3 9.1 4.4 56 3.9 0.1 4.1 2 1 4 6 6 6 0 Dinitrogenase iron-molybdenum cofactor HHH PF00633.18 EAU81226.2 - 3.2 7.6 7.7 81 3.2 0.1 4.9 4 0 0 4 4 4 0 Helix-hairpin-helix motif SNARE PF05739.14 EAU81229.2 - 5.6e-07 29.1 1.5 8.6e-07 28.5 1.1 1.3 1 0 0 1 1 1 1 SNARE domain H-kinase_dim PF02895.9 EAU81229.2 - 0.02 15.2 0.6 0.024 14.9 0.4 1.1 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF1515 PF07439.6 EAU81229.2 - 0.15 11.9 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Zn_clus PF00172.13 EAU81232.2 - 1.4e-05 24.8 9.2 2.4e-05 24.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EAU81232.2 - 0.0068 16.1 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold DUF104 PF01954.11 EAU81232.2 - 0.1 12.6 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF104 TFIIA PF03153.8 EAU81232.2 - 0.13 12.0 1.5 0.078 12.8 0.1 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_1 PF00232.13 EAU81233.2 - 4.4e-149 496.5 2.7 3.6e-148 493.5 1.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EAU81233.2 - 0.03 13.7 0.0 0.082 12.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core GFO_IDH_MocA PF01408.17 EAU81234.2 - 6.1e-15 55.8 0.1 1.4e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAU81234.2 - 6.2e-09 35.6 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EAU81234.2 - 0.029 14.7 0.2 0.056 13.8 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 EAU81237.2 - 1.2e-55 188.4 0.2 7.7e-49 166.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU81237.2 - 0.001 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU81237.2 - 0.014 14.6 0.2 5.6 6.1 0.1 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EAU81237.2 - 0.036 12.7 0.4 0.094 11.4 0.3 1.7 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_5 PF12695.2 EAU81237.2 - 0.037 13.7 0.1 0.056 13.2 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family SSP160 PF06933.6 EAU81237.2 - 2.5 5.9 10.1 3.4 5.5 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TMF_TATA_bd PF12325.3 EAU81238.2 - 0.15 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-RVT PF13966.1 EAU81240.2 - 0.011 15.9 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Peptidase_S32 PF05579.8 EAU81240.2 - 0.026 13.4 0.2 0.81 8.6 0.3 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.1 EAU81240.2 - 0.041 13.8 0.0 0.4 10.6 0.0 2.3 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_M36 PF02128.10 EAU81240.2 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) LRR_4 PF12799.2 EAU81241.1 - 1.9 8.2 7.0 0.92 9.2 0.7 3.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU81242.2 - 0.0052 16.5 1.8 0.046 13.4 0.1 3.2 3 1 0 3 3 3 1 Leucine rich repeat DUF4646 PF15496.1 EAU81245.1 - 1.4e-05 25.1 0.0 4.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 EAU81245.1 - 0.00024 20.9 0.1 0.0033 17.2 0.0 2.4 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF4326 PF14216.1 EAU81245.1 - 3.1 8.4 8.1 0.55 10.8 2.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4326) HMG_box PF00505.14 EAU81245.1 - 5.2 7.4 20.5 0.13 12.5 5.2 2.7 1 1 1 2 2 2 0 HMG (high mobility group) box MecA_N PF05223.6 EAU81245.1 - 5.5 7.0 13.9 2.8 8.0 8.0 1.7 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain Neur_chan_memb PF02932.11 EAU81245.1 - 8.2 6.2 12.3 13 5.5 8.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 EAU81246.2 - 0.75 9.3 16.2 1.3 8.5 11.2 1.4 1 0 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 EAU81246.2 - 0.79 7.9 13.4 1 7.5 9.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MAP7 PF05672.6 EAU81246.2 - 8.3 5.7 53.4 19 4.6 37.0 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Pap_E4 PF02711.9 EAU81260.1 - 6.4 7.6 6.3 11 6.9 0.8 2.4 1 1 1 2 2 2 0 E4 protein DUF4407 PF14362.1 EAU81263.2 - 0.032 13.2 1.5 0.059 12.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1434 PF07254.7 EAU81263.2 - 0.11 12.3 0.4 0.23 11.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1434) DUF1192 PF06698.6 EAU81266.2 - 0.0039 16.9 0.4 0.008 15.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Phasin PF05597.6 EAU81266.2 - 0.03 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3972 PF13118.1 EAU81266.2 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) RtcB PF01139.12 EAU81267.2 - 0.025 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB zf-C3HC4_3 PF13920.1 EAU81267.2 - 0.031 13.9 7.8 0.063 12.9 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4360 PF14273.1 EAU81273.2 - 7.2e-29 100.7 0.5 9e-29 100.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.1 EAU81274.2 - 1.6e-13 50.7 0.0 2.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.1 EAU81275.1 - 2.6e-23 82.6 2.3 2.9e-23 82.4 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase PF00069.20 EAU81277.2 - 0.017 14.2 0.0 0.04 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein kinase domain MIP-T3 PF10243.4 EAU81280.2 - 0.00016 20.3 24.3 0.00016 20.3 16.9 5.1 5 0 0 5 5 5 1 Microtubule-binding protein MIP-T3 F-box-like PF12937.2 EAU81282.1 - 0.0036 17.0 0.0 0.0091 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like PI-PLC-X PF00388.14 EAU81283.1 - 2.5e-53 179.3 0.0 4.4e-53 178.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EAU81283.1 - 6e-39 132.6 0.1 1.5e-38 131.3 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EAU81283.1 - 1.1e-08 34.9 4.1 3.7e-08 33.2 0.3 2.7 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EAU81283.1 - 1.7e-07 31.0 0.0 3.2e-06 26.8 0.0 2.6 1 1 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 EAU81283.1 - 3.1e-07 30.4 0.7 9.6e-07 28.8 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.1 EAU81283.1 - 3.8e-06 26.4 0.5 8.5e-06 25.3 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 EAU81283.1 - 2.7e-05 23.1 0.7 0.0076 15.4 0.2 2.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EAU81283.1 - 0.0089 15.8 4.2 0.14 12.1 0.8 3.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_4 PF12763.2 EAU81283.1 - 0.11 12.2 0.1 0.38 10.4 0.1 1.9 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF4470 PF14737.1 EAU81284.1 - 1.2e-12 47.3 0.0 1.5e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EAU81284.1 - 5.5e-10 38.7 1.0 1.3e-09 37.5 0.7 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EAU81284.1 - 1.5e-05 24.5 1.3 0.0018 18.0 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU81284.1 - 0.00043 19.7 2.3 0.0032 17.0 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU81284.1 - 0.00059 20.4 0.1 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU81284.1 - 0.0016 18.3 0.3 0.0053 16.6 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU81284.1 - 0.023 14.8 0.1 0.062 13.4 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EAU81284.1 - 0.039 13.7 2.3 0.049 13.4 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CAAD PF14159.1 EAU81286.2 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase FH2 PF02181.18 EAU81287.2 - 0.001 18.0 2.0 0.0022 16.9 1.4 1.5 1 1 0 1 1 1 1 Formin Homology 2 Domain BLOC1_2 PF10046.4 EAU81287.2 - 0.0033 17.5 2.5 0.0042 17.2 0.8 1.8 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.4 EAU81287.2 - 0.0075 16.3 7.7 0.0096 15.9 5.3 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein DUF812 PF05667.6 EAU81287.2 - 0.014 13.9 2.2 0.015 13.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ERM PF00769.14 EAU81287.2 - 0.017 14.6 10.4 0.029 13.9 7.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tup_N PF08581.5 EAU81287.2 - 0.025 14.7 8.5 0.15 12.2 0.8 2.9 2 1 1 3 3 3 0 Tup N-terminal AF0941-like PF14591.1 EAU81287.2 - 0.037 14.0 4.3 0.058 13.4 3.0 1.3 1 0 0 1 1 1 0 AF0941-like Spc7 PF08317.6 EAU81287.2 - 0.04 12.5 8.7 0.057 12.0 6.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RabGAP-TBC PF00566.13 EAU81287.2 - 0.044 13.2 0.7 0.12 11.8 0.1 1.8 1 1 1 2 2 2 0 Rab-GTPase-TBC domain DUF1664 PF07889.7 EAU81287.2 - 0.05 13.4 0.9 0.38 10.5 0.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) EzrA PF06160.7 EAU81287.2 - 0.053 11.6 5.9 0.071 11.2 4.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2115 PF09888.4 EAU81287.2 - 0.069 13.2 0.5 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) APG6 PF04111.7 EAU81287.2 - 0.074 12.0 5.5 0.095 11.7 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Laminin_II PF06009.7 EAU81287.2 - 0.1 12.3 4.2 0.22 11.2 2.9 1.6 1 1 0 1 1 1 0 Laminin Domain II DUF4164 PF13747.1 EAU81287.2 - 0.11 12.5 11.0 0.052 13.6 5.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4164) Hemerythrin PF01814.18 EAU81287.2 - 0.15 12.1 4.8 0.46 10.6 3.4 1.7 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain ATG16 PF08614.6 EAU81287.2 - 0.16 11.8 9.0 0.21 11.3 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) EMP24_GP25L PF01105.19 EAU81287.2 - 0.23 11.1 4.4 0.73 9.5 0.6 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF972 PF06156.8 EAU81287.2 - 0.28 11.5 7.3 0.32 11.3 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PXA PF02194.10 EAU81287.2 - 0.28 10.7 4.2 0.36 10.3 2.9 1.1 1 0 0 1 1 1 0 PXA domain Phage_GP20 PF06810.6 EAU81287.2 - 0.3 10.5 2.9 0.55 9.6 2.0 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 CCDC155 PF14662.1 EAU81287.2 - 0.31 10.6 9.0 0.6 9.6 6.3 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF4472 PF14739.1 EAU81287.2 - 0.32 11.4 6.1 0.52 10.7 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) FliJ PF02050.11 EAU81287.2 - 0.35 10.9 6.3 0.5 10.4 4.4 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein ADIP PF11559.3 EAU81287.2 - 0.38 10.6 8.4 0.8 9.5 5.8 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding DFF-C PF09033.5 EAU81287.2 - 0.41 10.4 4.3 0.56 10.0 2.1 1.8 1 1 1 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain XhlA PF10779.4 EAU81287.2 - 0.66 9.9 4.5 0.31 10.9 1.1 2.0 1 1 1 2 2 2 0 Haemolysin XhlA V_ATPase_I PF01496.14 EAU81287.2 - 0.66 7.7 3.4 0.83 7.4 2.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EAU81287.2 - 0.72 9.9 8.3 0.45 10.5 3.7 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SPT16 PF08644.6 EAU81287.2 - 0.83 9.4 4.8 3.7 7.3 3.2 2.1 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Snapin_Pallidin PF14712.1 EAU81287.2 - 0.89 9.9 5.3 2 8.7 1.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin IncA PF04156.9 EAU81287.2 - 0.91 9.0 11.9 1.7 8.1 8.1 1.4 1 1 0 1 1 1 0 IncA protein WD40_alt PF14077.1 EAU81287.2 - 1.3 8.7 20.8 0.14 11.7 1.6 4.0 2 1 2 4 4 4 0 Alternative WD40 repeat motif Jnk-SapK_ap_N PF09744.4 EAU81287.2 - 2.1 8.3 11.3 0.91 9.4 2.3 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3552 PF12072.3 EAU81287.2 - 3.4 6.8 13.0 0.42 9.7 6.1 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF3552) GrpE PF01025.14 EAU81287.2 - 4.6 6.7 8.7 19 4.7 5.9 1.8 1 1 0 1 1 1 0 GrpE DivIC PF04977.10 EAU81287.2 - 7.5 6.1 9.5 3.9 7.0 0.6 2.9 2 1 1 3 3 3 0 Septum formation initiator DUF3782 PF12644.2 EAU81287.2 - 9.7 6.0 6.9 2.4e+02 1.6 4.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) SOG2 PF10428.4 EAU81288.1 - 2.2 6.8 9.0 3.7 6.0 6.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4218 PF13960.1 EAU81289.2 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EAU81289.2 - 0.084 11.9 0.7 7.8 5.5 0.2 2.4 2 0 0 2 2 2 0 Transposase family tnp2 Phage_int_SAM_2 PF12834.2 EAU81292.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal DUF3505 PF12013.3 EAU81294.2 - 0.0051 17.0 0.1 0.04 14.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) AT_hook PF02178.14 EAU81294.2 - 0.021 14.4 23.2 0.4 10.4 4.5 3.1 2 0 0 2 2 2 0 AT hook motif PHD PF00628.24 EAU81295.2 - 0.00015 21.4 8.6 0.00038 20.0 5.9 1.8 1 0 0 1 1 1 1 PHD-finger Rubredoxin PF00301.15 EAU81295.2 - 0.039 13.8 5.7 0.12 12.2 3.9 1.9 1 0 0 1 1 1 0 Rubredoxin C1_1 PF00130.17 EAU81295.2 - 3.7 7.3 8.0 0.28 10.9 1.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Metallophos_2 PF12850.2 EAU81296.2 - 3.9e-06 26.7 0.0 1.1e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_2 PF12850.2 EAU81297.2 - 4.3e-06 26.6 0.0 1.1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAU81297.2 - 8.3e-05 22.0 4.7 0.00025 20.5 3.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NIR_SIR PF01077.17 EAU81298.2 - 7.9e-31 106.5 0.1 1.5e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EAU81298.2 - 3.2e-18 66.3 0.0 6.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.12 EAU81298.2 - 1.4e-11 43.8 0.0 3.4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox PF00070.22 EAU81298.2 - 1.5e-11 44.5 0.0 3.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 EAU81298.2 - 1.8e-11 43.9 2.1 3e-08 33.6 1.5 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske_2 PF13806.1 EAU81298.2 - 2.1e-09 37.0 0.0 9.1e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 EAU81298.2 - 0.0051 15.7 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EAU81298.2 - 0.088 12.8 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EAU81299.2 - 1.6e-28 99.4 20.6 1.6e-28 99.4 14.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU81299.2 - 0.00077 18.1 8.8 0.00077 18.1 6.1 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter LysE PF01810.13 EAU81299.2 - 0.97 8.6 11.8 0.23 10.7 0.1 3.7 4 0 0 4 4 4 0 LysE type translocator Mo-co_dimer PF03404.11 EAU81300.2 - 1.3e-51 173.6 0.0 2.2e-51 172.9 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EAU81300.2 - 5.7e-51 172.2 0.0 1.1e-50 171.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EAU81300.2 - 1.3e-23 83.0 0.0 3.4e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EAU81300.2 - 6.4e-22 77.1 0.0 1.3e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EAU81300.2 - 2.8e-21 76.1 0.0 5.9e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EAU81300.2 - 0.00029 20.7 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain HCBP_related PF06594.6 EAU81300.2 - 0.0041 16.7 0.2 0.0093 15.5 0.2 1.7 1 0 0 1 1 1 1 Haemolysin-type calcium binding protein related domain Phenyl_P_gamma PF09662.5 EAU81300.2 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF1996 PF09362.5 EAU81302.2 - 2.5e-68 230.2 0.0 3.3e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CHAT PF12770.2 EAU81303.2 - 6.9e-14 51.6 0.9 2.7e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 CHAT domain TPR_11 PF13414.1 EAU81303.2 - 3.4e-08 33.0 5.7 0.098 12.3 0.7 5.5 4 3 1 5 5 5 3 TPR repeat TPR_12 PF13424.1 EAU81303.2 - 2.7e-06 27.2 16.1 0.29 11.1 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU81303.2 - 0.0039 16.9 6.9 17 5.6 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU81303.2 - 0.0045 16.6 3.6 35 4.5 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU81303.2 - 0.12 12.0 3.7 20 4.9 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAU81303.2 - 0.13 12.6 1.9 36 4.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU81303.2 - 2.4 8.1 14.2 8.7 6.4 0.0 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 EAU81305.1 - 7.6e-25 85.8 15.0 3.6e-08 32.9 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.7 EAU81305.1 - 7.1e-16 57.9 0.0 1.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain OspD PF03207.8 EAU81305.1 - 0.12 11.5 0.2 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) DUF1202 PF06717.6 EAU81307.1 - 0.15 11.3 2.0 0.24 10.6 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) cEGF PF12662.2 EAU81307.1 - 0.18 11.4 1.1 0.33 10.6 0.8 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like Orbi_NS3 PF01616.11 EAU81311.2 - 0.046 12.6 0.2 0.046 12.6 0.1 1.7 2 0 0 2 2 2 0 Orbivirus NS3 VKOR PF07884.9 EAU81315.2 - 2.4 7.9 16.6 1.1 9.1 2.1 3.4 2 2 0 3 3 3 0 Vitamin K epoxide reductase family CH PF00307.26 EAU81316.1 - 0.022 14.7 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF1394 PF07159.7 EAU81316.1 - 0.032 13.3 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) DUF3829 PF12889.2 EAU81316.1 - 0.036 13.2 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2746 PF10874.3 EAU81316.1 - 0.061 13.5 0.1 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Nup54 PF13874.1 EAU81317.1 - 0.0065 16.1 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 EAU81317.1 - 0.017 14.8 1.0 0.024 14.3 0.7 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Paramyxo_P PF01806.12 EAU81317.1 - 0.083 12.1 0.2 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region DUF4200 PF13863.1 EAU81317.1 - 0.086 12.7 5.5 0.15 12.0 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4254 PF14063.1 EAU81317.1 - 0.12 11.9 2.6 0.39 10.3 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) IncA PF04156.9 EAU81317.1 - 0.12 11.9 1.4 0.18 11.4 1.0 1.2 1 0 0 1 1 1 0 IncA protein COG2 PF06148.6 EAU81317.1 - 0.13 12.1 1.1 0.22 11.4 0.7 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.14 EAU81317.1 - 0.39 10.2 2.4 0.57 9.7 1.7 1.1 1 0 0 1 1 1 0 GrpE Herpes_LMP2 PF07415.6 EAU81323.2 - 0.52 8.8 0.4 23 3.3 0.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein HMG_box_2 PF09011.5 EAU81324.1 - 5.9e-06 26.5 1.9 2.9e-05 24.3 1.3 2.2 1 0 0 1 1 1 1 HMG-box domain FlxA PF14282.1 EAU81325.2 - 0.0022 17.8 1.2 0.0022 17.8 0.8 3.0 3 0 0 3 3 3 1 FlxA-like protein Ebola_NP PF05505.7 EAU81334.1 - 0.052 11.6 0.0 0.086 10.8 0.0 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Pkinase PF00069.20 EAU81338.1 - 7.6e-06 25.2 0.0 1.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Peroxin-3 PF04882.7 EAU81340.1 - 6.2e-85 285.5 0.0 6.9e-73 245.7 0.2 2.4 2 1 0 2 2 2 2 Peroxin-3 Uds1 PF15456.1 EAU81340.1 - 0.012 15.5 2.2 0.32 10.9 0.0 2.8 2 0 0 2 2 2 0 Up-regulated During Septation Acetyltransf_1 PF00583.19 EAU81346.2 - 3.8e-11 42.8 0.0 6.3e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU81346.2 - 4.3e-06 26.7 0.0 7.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAU81346.2 - 0.00022 21.3 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAU81346.2 - 0.011 15.5 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fil_haemagg_2 PF13332.1 EAU81346.2 - 0.069 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Haemagluttinin repeat Acetyltransf_9 PF13527.1 EAU81346.2 - 0.077 12.8 0.0 0.58 10.0 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAU81346.2 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CDC45 PF02724.9 EAU81347.1 - 0.0026 15.8 1.4 0.0035 15.4 1.0 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.7 EAU81347.1 - 0.027 13.7 2.4 0.031 13.5 1.7 1.1 1 0 0 1 1 1 0 SDA1 YL1 PF05764.8 EAU81347.1 - 0.067 12.7 2.1 0.087 12.4 1.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EAU81347.1 - 0.082 10.8 4.4 0.099 10.5 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family SpoVIF PF14069.1 EAU81347.1 - 0.11 12.2 0.3 0.19 11.5 0.2 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F BUD22 PF09073.5 EAU81347.1 - 0.52 9.3 4.4 0.79 8.7 3.0 1.2 1 0 0 1 1 1 0 BUD22 Aldedh PF00171.17 EAU81348.1 - 2.7e-128 428.2 0.0 3.2e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EAU81348.1 - 3.2e-09 36.0 0.0 4.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) AA_kinase PF00696.23 EAU81349.2 - 1.2e-37 129.7 0.0 1.1e-32 113.5 0.0 2.3 2 0 0 2 2 2 2 Amino acid kinase family ACT_7 PF13840.1 EAU81349.2 - 1.1e-11 44.0 2.1 4.8e-09 35.5 0.2 2.9 3 0 0 3 3 3 2 ACT domain ACT PF01842.20 EAU81349.2 - 1.2e-10 40.6 4.9 4.4e-07 29.2 0.1 3.3 3 0 0 3 3 3 2 ACT domain FMN_red PF03358.10 EAU81349.2 - 0.064 12.7 0.1 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Pkinase PF00069.20 EAU81350.2 - 0.00071 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU81350.2 - 0.037 13.7 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCCH PF00642.19 EAU81351.2 - 4.2e-09 35.8 6.9 0.016 14.8 2.1 3.7 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EAU81351.2 - 1.5e-07 30.9 0.0 1.7e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU81351.2 - 4.2e-07 29.8 0.0 7.3e-06 25.8 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_4 PF15227.1 EAU81351.2 - 8.6e-07 28.7 5.4 8.6e-07 28.7 3.7 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING RRM_5 PF13893.1 EAU81351.2 - 2e-06 27.5 0.0 0.0033 17.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EAU81351.2 - 5.4e-06 26.3 2.7 5.4e-06 26.3 1.9 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU81351.2 - 3.1e-05 23.5 5.3 8.1e-05 22.2 3.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU81351.2 - 0.00086 19.0 6.4 0.00086 19.0 4.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EAU81351.2 - 0.0014 18.2 4.7 0.0041 16.8 3.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Limkain-b1 PF11608.3 EAU81351.2 - 0.0032 17.1 0.0 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 Limkain b1 zf-RING_UBOX PF13445.1 EAU81351.2 - 0.0064 16.1 3.3 0.019 14.6 2.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Fer2 PF00111.22 EAU81351.2 - 0.017 14.8 1.6 0.042 13.5 1.1 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-C3HC4_3 PF13920.1 EAU81351.2 - 0.78 9.4 14.2 0.063 12.9 5.7 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GST_N PF02798.15 EAU81355.2 - 2.3e-11 43.6 0.0 3.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAU81355.2 - 2.1e-08 34.2 0.0 5.5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EAU81355.2 - 1.2e-07 32.1 0.0 1.6e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EAU81355.2 - 1.6e-06 28.0 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU81355.2 - 0.0018 18.1 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU81355.2 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Phage_portal_2 PF05136.8 EAU81356.2 - 0.023 13.2 0.1 0.034 12.6 0.1 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family AdoHcyase PF05221.12 EAU81357.2 - 5.3e-141 468.2 0.0 6e-141 468.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EAU81357.2 - 3.9e-86 286.9 0.7 6e-86 286.3 0.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EAU81357.2 - 3.1e-08 32.9 0.0 6.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EAU81357.2 - 3.1e-05 23.3 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EAU81357.2 - 0.00073 19.5 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EAU81357.2 - 0.024 14.2 0.1 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 EAU81357.2 - 0.035 14.5 0.1 0.084 13.3 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TMEM107 PF14995.1 EAU81357.2 - 0.09 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Fork_head_N PF08430.7 EAU81363.1 - 0.36 11.2 4.4 9.7 6.5 0.1 2.6 2 0 0 2 2 2 0 Forkhead N-terminal region ABC_tran PF00005.22 EAU81372.2 - 8.2e-19 68.2 0.0 1.3e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AA_permease_N PF08403.5 EAU81372.2 - 0.018 14.3 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal ABC_membrane PF00664.18 EAU81372.2 - 0.047 13.0 2.9 0.093 12.1 1.8 1.6 1 1 1 2 2 2 0 ABC transporter transmembrane region VirC1 PF07015.6 EAU81373.2 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein zf-MYND PF01753.13 EAU81374.2 - 2.5e-10 40.0 16.8 6.1e-10 38.8 11.7 1.7 1 0 0 1 1 1 1 MYND finger Bestrophin PF01062.16 EAU81378.1 - 8.3e-51 172.6 0.1 6.8e-30 104.0 0.1 2.0 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel TT_ORF2 PF02957.10 EAU81379.2 - 0.97 10.1 4.3 0.63 10.7 0.3 2.4 2 0 0 2 2 2 0 TT viral ORF2 Ad_cyc_g-alpha PF08509.6 EAU81379.2 - 1.7 8.0 4.4 4.2 6.7 2.1 2.4 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain p450 PF00067.17 EAU81380.2 - 3.8e-67 226.7 0.0 4.4e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_88 PF07470.8 EAU81382.1 - 6.3e-16 58.3 0.0 2.8e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.8 EAU81383.2 - 2e-11 43.5 0.1 5.8e-11 42.0 0.1 1.6 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 p450 PF00067.17 EAU81384.2 - 8e-64 215.8 0.0 9.8e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EPL1 PF10513.4 EAU81386.1 - 1.6e-18 67.4 0.1 1.6e-18 67.4 0.1 2.8 2 1 0 2 2 2 1 Enhancer of polycomb-like APC_CDC26 PF10471.4 EAU81386.1 - 0.017 15.8 3.6 0.017 15.8 2.5 4.1 6 0 0 6 6 6 0 Anaphase-promoting complex APC subunit 1 Oxidored-like PF09791.4 EAU81387.2 - 2.3e-16 58.9 0.7 5.7e-16 57.6 0.5 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF1244 PF06844.6 EAU81387.2 - 0.11 12.2 0.1 0.36 10.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1244) Transp_cyt_pur PF02133.10 EAU81388.1 - 9.5e-24 83.7 39.1 1e-22 80.3 27.1 1.9 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 EAU81390.1 - 1.9e-30 105.8 38.8 5e-30 104.4 26.9 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MutS_V PF00488.16 EAU81391.2 - 1.5e-97 325.6 0.0 2.5e-97 324.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAU81391.2 - 2.1e-34 119.1 0.1 4.7e-34 117.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EAU81391.2 - 5.4e-16 58.5 0.6 1.4e-15 57.2 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EAU81391.2 - 2.3e-14 53.6 0.0 7.4e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 EAU81391.2 - 3.9e-09 36.5 0.0 8.7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I AAA_23 PF13476.1 EAU81391.2 - 0.43 10.8 5.8 18 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF1275 PF06912.6 EAU81392.2 - 8.3e-21 74.1 20.5 2.6e-20 72.5 14.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1275 PF06912.6 EAU81393.2 - 8.8e-13 47.9 12.0 1.1e-12 47.6 7.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) P5CR_dimer PF14748.1 EAU81394.2 - 0.038 14.0 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyrroline-5-carboxylate reductase dimerisation ATP1G1_PLM_MAT8 PF02038.11 EAU81394.2 - 0.44 9.6 3.4 11 5.1 2.2 2.8 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Motile_Sperm PF00635.21 EAU81396.2 - 5.2e-16 58.2 0.0 7.1e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Motile_Sperm PF00635.21 EAU81397.2 - 2.7e-17 62.3 0.0 3.4e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PAM2 PF07145.10 EAU81397.2 - 0.13 11.8 2.0 0.32 10.6 1.4 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Borrelia_P83 PF05262.6 EAU81400.1 - 0.00042 18.7 1.1 0.00042 18.7 0.8 6.2 4 2 3 7 7 7 1 Borrelia P83/100 protein Trypan_PARP PF05887.6 EAU81400.1 - 0.00046 20.0 45.6 0.00046 20.0 31.6 9.0 6 3 2 8 8 8 1 Procyclic acidic repetitive protein (PARP) Drf_GBD PF06371.8 EAU81401.1 - 0.41 9.9 6.1 0.86 8.9 4.2 1.5 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain F-box PF00646.28 EAU81402.2 - 0.0067 16.0 0.0 0.019 14.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EAU81405.1 - 0.0067 16.0 2.7 5.1 6.8 0.3 3.8 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EAU81405.1 - 0.0093 15.6 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAU81405.1 - 0.038 13.7 1.2 13 5.6 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat DUF2408 PF10303.4 EAU81405.1 - 0.099 12.7 0.0 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Pyridoxal_deC PF00282.14 EAU81406.1 - 8.8e-63 211.9 0.0 1.2e-62 211.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EAU81406.1 - 0.0022 16.8 0.0 0.0033 16.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_L16 PF00252.13 EAU81407.1 - 2.1e-36 124.6 0.5 2.6e-36 124.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SLT_2 PF13406.1 EAU81407.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase SLT domain PRP3 PF08572.5 EAU81408.2 - 7.2e-64 215.2 6.8 7.2e-64 215.2 4.7 1.5 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EAU81408.2 - 8.9e-34 115.9 0.0 2.6e-33 114.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3328 PF11807.3 EAU81410.2 - 0.044 13.4 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4081 PF13312.1 EAU81410.2 - 0.072 13.0 1.6 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) adh_short PF00106.20 EAU81412.1 - 4.9e-07 29.8 0.0 6.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU81412.1 - 0.039 13.6 0.0 0.094 12.3 0.0 1.6 1 1 0 1 1 1 0 KR domain DUF3596 PF12167.3 EAU81413.2 - 0.04 13.4 0.2 0.14 11.6 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) p450 PF00067.17 EAU81414.2 - 5.9e-55 186.6 0.0 1.2e-52 179.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ORC2 PF04084.9 EAU81415.2 - 4e-79 265.8 0.0 5.1e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 TFIIE-A_C-term PF11521.3 EAU81415.2 - 0.021 14.7 2.8 0.062 13.2 1.0 2.3 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha HHH_2 PF12826.2 EAU81415.2 - 0.039 13.8 0.2 9.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ricin_B_lectin PF00652.17 EAU81416.1 - 1.2e-16 60.8 0.2 2.1e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU81416.1 - 1.1e-10 41.7 0.2 1.1e-09 38.6 0.0 2.3 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_1 PF00232.13 EAU81417.2 - 1e-131 439.3 0.6 2.6e-131 437.9 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Mito_carr PF00153.22 EAU81419.2 - 1.1e-56 188.5 6.7 3.4e-22 77.9 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein His_Phos_2 PF00328.17 EAU81420.2 - 2e-24 86.5 0.0 7.1e-24 84.7 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DCP1 PF06058.8 EAU81422.1 - 2.5e-15 56.5 0.0 1e-13 51.4 0.0 2.2 2 0 0 2 2 2 1 Dcp1-like decapping family RAG2 PF03089.9 EAU81422.1 - 0.21 10.2 1.5 0.33 9.6 0.0 1.8 2 0 0 2 2 2 0 Recombination activating protein 2 F-box PF00646.28 EAU81423.1 - 2.4e-05 23.8 0.1 6.6e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU81423.1 - 0.00094 18.8 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU81423.1 - 0.0024 17.4 0.0 3.4 7.3 0.0 3.6 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU81423.1 - 0.023 14.4 0.1 5.2 6.9 0.1 3.1 2 0 0 2 2 2 0 Leucine rich repeat Pmp3 PF01679.12 EAU81424.1 - 1.5e-16 59.8 5.6 1.8e-16 59.5 3.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.3 EAU81424.1 - 0.11 12.2 1.1 0.16 11.7 0.8 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal UCH PF00443.24 EAU81425.1 - 1.3e-41 142.5 0.0 1.4e-37 129.3 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU81425.1 - 4.4e-10 39.4 0.0 1.8e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase F-box-like PF12937.2 EAU81426.2 - 9.4e-09 34.8 0.0 1.8e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU81426.2 - 5.8e-06 25.8 0.0 2.7e-05 23.6 0.0 2.3 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EAU81426.2 - 0.0011 18.5 0.3 0.32 10.6 0.0 3.7 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAU81426.2 - 0.01 15.8 0.3 36 5.1 0.0 4.3 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 EAU81426.2 - 0.013 15.2 0.1 0.082 12.6 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 EAU81426.2 - 0.035 14.1 0.5 4.6 7.6 0.0 3.7 3 1 0 3 3 3 0 Leucine Rich Repeat AMP-binding PF00501.23 EAU81427.2 - 2.8e-79 266.4 0.0 3.3e-78 262.9 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU81427.2 - 7.5e-09 36.4 0.0 2.3e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain tRNA-synt_1 PF00133.17 EAU81428.2 - 4e-152 507.3 0.0 4.9e-152 507.0 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EAU81428.2 - 8.1e-20 70.8 0.0 5.9e-13 48.2 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EAU81428.2 - 1.4e-19 70.3 0.0 3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EAU81428.2 - 1.9e-07 30.5 5.3 4.9e-07 29.2 3.6 1.8 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EAU81428.2 - 0.0025 17.0 0.0 0.79 8.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DZR PF12773.2 EAU81428.2 - 0.2 11.5 0.6 0.38 10.5 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon F-box-like PF12937.2 EAU81429.2 - 0.036 13.8 1.0 0.23 11.2 0.1 2.6 2 0 0 2 2 2 0 F-box-like DUF515 PF04415.7 EAU81429.2 - 1.9 6.6 9.1 2.9 6.0 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) ProRS-C_1 PF09180.6 EAU81430.2 - 2.6e-26 91.3 0.8 5.9e-26 90.1 0.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EAU81430.2 - 4.9e-17 61.6 0.0 1.3e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EAU81430.2 - 5.1e-16 58.7 0.0 9.8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.10 EAU81430.2 - 1.1e-15 57.5 0.1 1.9e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Bin3 PF06859.7 EAU81431.2 - 1e-31 109.1 0.0 2.4e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_11 PF08241.7 EAU81431.2 - 0.082 13.4 0.0 3.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain SURF4 PF02077.10 EAU81432.1 - 9.6e-97 323.5 7.3 1.1e-96 323.3 5.1 1.0 1 0 0 1 1 1 1 SURF4 family SURF4 PF02077.10 EAU81433.1 - 1.3e-87 293.6 2.1 1.5e-87 293.4 1.5 1.0 1 0 0 1 1 1 1 SURF4 family Gti1_Pac2 PF09729.4 EAU81436.2 - 2.5e-21 76.2 3.5 1.4e-18 67.3 0.1 3.1 3 0 0 3 3 3 2 Gti1/Pac2 family DUF155 PF02582.9 EAU81437.2 - 4.5e-45 153.6 0.0 8.1e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 GRA6 PF05084.8 EAU81437.2 - 0.16 11.4 1.3 0.29 10.6 0.9 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Sec5 PF15469.1 EAU81438.2 - 3.1e-56 189.9 1.6 1.6e-55 187.6 0.3 2.8 4 0 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.6 EAU81438.2 - 0.0011 18.8 0.0 0.0049 16.6 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Phasin_2 PF09361.5 EAU81438.2 - 0.76 9.8 6.7 2.5 8.1 0.1 3.4 3 0 0 3 3 3 0 Phasin protein SURF4 PF02077.10 EAU81440.1 - 1.1e-09 38.1 0.3 1.3e-09 37.8 0.2 1.1 1 0 0 1 1 1 1 SURF4 family NUC153 PF08159.7 EAU81442.1 - 7e-13 47.9 0.3 1.4e-12 46.9 0.2 1.5 1 0 0 1 1 1 1 NUC153 domain ADH_N PF08240.7 EAU81443.2 - 2e-31 107.9 2.4 4.1e-31 106.9 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU81443.2 - 5.1e-09 35.7 0.0 2.6e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EAU81443.2 - 0.048 13.3 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated HMG-CoA_red PF00368.13 EAU81445.1 - 5.2e-159 528.8 5.4 7.2e-159 528.4 3.7 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EAU81445.1 - 3.8e-09 36.1 0.7 0.0013 18.2 0.1 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Herpes_LMP1 PF05297.6 EAU81445.1 - 0.66 8.8 3.8 1.6 7.6 2.7 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) HPIH PF13323.1 EAU81445.1 - 0.69 9.5 5.6 0.056 13.1 0.2 1.9 2 0 0 2 2 2 0 N-terminal domain with HPIH motif Ribosomal_L44 PF00935.14 EAU81446.2 - 1.7e-35 120.8 11.7 2.6e-35 120.2 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Acetyltransf_3 PF13302.1 EAU81447.2 - 3e-07 30.6 0.0 6.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU81447.2 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU81447.2 - 0.014 15.4 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HEAT_2 PF13646.1 EAU81450.2 - 0.00018 21.7 10.1 0.34 11.2 0.2 5.9 3 2 2 6 6 6 4 HEAT repeats Nucleo_P87 PF07267.6 EAU81450.2 - 0.022 13.4 1.4 0.039 12.6 1.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HEAT PF02985.17 EAU81450.2 - 3.4 8.0 9.2 6.3 7.1 0.0 6.1 8 0 0 8 8 8 0 HEAT repeat COesterase PF00135.23 EAU81452.2 - 2.7e-57 194.6 0.0 5.6e-56 190.3 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU81452.2 - 0.0034 16.9 0.3 0.0073 15.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EAU81452.2 - 0.094 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) SRP19 PF01922.12 EAU81453.2 - 1.5e-22 79.9 0.0 2.2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein C1-set PF07654.10 EAU81453.2 - 0.041 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain JTB PF05439.7 EAU81454.2 - 0.00032 20.4 0.0 0.00034 20.3 0.0 1.0 1 0 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) Glyco_hydro_18 PF00704.23 EAU81455.1 - 1.5e-63 215.3 0.0 2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_11 PF13414.1 EAU81456.1 - 9.1e-08 31.6 6.5 9.1e-05 22.0 0.5 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EAU81456.1 - 9.8e-06 24.9 3.4 0.078 12.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU81456.1 - 0.00011 21.8 5.8 0.087 12.7 0.7 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU81456.1 - 0.0011 18.9 3.5 0.0016 18.4 1.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU81456.1 - 0.0012 18.5 2.8 1.1 9.2 0.1 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU81456.1 - 0.018 15.7 3.2 2.2 9.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAU81456.1 - 0.1 12.4 2.3 0.18 11.6 0.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU81456.1 - 0.1 12.5 1.7 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF859 PF05895.7 EAU81456.1 - 0.15 10.2 0.0 0.21 9.8 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) TPR_14 PF13428.1 EAU81456.1 - 0.2 12.3 4.5 1.8 9.3 0.2 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAU81456.1 - 0.23 11.8 3.3 0.3 11.4 0.9 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU81456.1 - 3.2 8.4 5.7 18 6.0 1.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SET PF00856.23 EAU81457.1 - 1.5e-11 44.8 0.0 6.4e-11 42.8 0.0 2.0 1 1 0 1 1 1 1 SET domain HTH_21 PF13276.1 EAU81457.1 - 0.00015 21.6 0.0 0.00043 20.2 0.0 1.8 1 0 0 1 1 1 1 HTH-like domain Myticin-prepro PF10690.4 EAU81457.1 - 0.12 12.3 3.7 5.7 7.0 0.7 2.4 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Glyco_hydro_18 PF00704.23 EAU81461.1 - 1.4e-61 208.8 0.2 1.9e-61 208.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF187 PF02638.10 EAU81461.1 - 0.0071 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 BCNT PF07572.7 EAU81462.1 - 9.2e-19 67.1 0.3 1.7e-18 66.3 0.2 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development TH1 PF04858.8 EAU81462.1 - 0.12 10.5 1.0 0.16 10.0 0.7 1.1 1 0 0 1 1 1 0 TH1 protein CDC45 PF02724.9 EAU81462.1 - 2.3 6.1 7.1 3.1 5.7 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein MCPVI PF02993.9 EAU81462.1 - 5.5 7.0 15.1 1.1 9.3 5.1 2.1 1 1 1 2 2 2 0 Minor capsid protein VI DSPc PF00782.15 EAU81463.1 - 0.00046 19.7 0.0 0.0012 18.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EAU81463.1 - 0.0073 16.5 0.0 0.026 14.7 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1032 PF06278.6 EAU81463.1 - 0.018 13.5 0.0 0.033 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1032) PTPlike_phytase PF14566.1 EAU81463.1 - 0.046 13.7 0.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 EAU81463.1 - 0.17 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase OPA3 PF07047.7 EAU81464.1 - 9.5e-37 125.7 0.2 1.3e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) IncA PF04156.9 EAU81464.1 - 0.0014 18.2 0.2 0.0023 17.5 0.2 1.3 1 0 0 1 1 1 1 IncA protein FlxA PF14282.1 EAU81464.1 - 0.0092 15.9 0.5 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 FlxA-like protein EAP30 PF04157.11 EAU81464.1 - 0.025 13.7 0.3 0.34 10.0 0.1 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family RPW8 PF05659.6 EAU81464.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Osmo_CC PF08946.5 EAU81464.1 - 0.13 12.3 0.7 0.68 10.0 0.0 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Snf7 PF03357.16 EAU81464.1 - 0.32 10.3 2.6 7.1 5.9 0.4 2.1 2 0 0 2 2 2 0 Snf7 Alpha-L-AF_C PF06964.7 EAU81465.2 - 9.7e-22 77.5 0.3 2.4e-10 40.4 0.0 2.8 2 1 1 3 3 3 2 Alpha-L-arabinofuranosidase C-terminus CBM_6 PF03422.10 EAU81465.2 - 4.9e-05 23.4 2.2 4.9e-05 23.4 1.5 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) Gmad2 PF10648.4 EAU81465.2 - 0.0016 18.5 0.4 0.038 14.1 0.1 2.4 2 0 0 2 2 2 1 Immunoglobulin-like domain of bacterial spore germination CBM_4_9 PF02018.12 EAU81465.2 - 0.0051 16.8 0.1 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain DUF4082 PF13313.1 EAU81465.2 - 0.04 13.3 3.2 0.12 11.7 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4082) Ribosomal_S8 PF00410.14 EAU81466.2 - 1.6e-17 63.5 0.0 2.7e-17 62.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 RicinB_lectin_2 PF14200.1 EAU81467.1 - 3.3e-28 98.1 14.5 1.4e-17 63.9 2.3 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU81467.1 - 3.9e-08 33.3 2.5 1.3e-06 28.4 0.4 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain FGF PF00167.13 EAU81467.1 - 0.00014 21.6 0.1 0.00048 19.9 0.0 1.9 1 1 1 2 2 2 1 Fibroblast growth factor Botulinum_HA-17 PF05588.6 EAU81467.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein RicinB_lectin_2 PF14200.1 EAU81468.2 - 4e-32 110.6 4.5 3.4e-21 75.5 0.2 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU81468.2 - 8.6e-06 25.7 0.1 0.0053 16.7 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Flavi_NS2B PF01002.14 EAU81468.2 - 0.075 12.6 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2B FGF PF00167.13 EAU81468.2 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibroblast growth factor RicinB_lectin_2 PF14200.1 EAU81469.2 - 1.7e-17 63.7 1.4 1.4e-10 41.5 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU81469.2 - 1e-06 28.8 0.2 0.034 14.1 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain FGF PF00167.13 EAU81469.2 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Fibroblast growth factor MatE PF01554.13 EAU81470.1 - 2.1e-49 167.2 25.2 3.7e-29 101.4 5.8 2.4 2 0 0 2 2 2 2 MatE Bac_surface_Ag PF01103.18 EAU81471.1 - 1.2e-40 139.9 0.2 1.6e-40 139.5 0.1 1.2 1 0 0 1 1 1 1 Surface antigen Hist_deacetyl PF00850.14 EAU81472.2 - 1.4e-52 178.9 0.0 1.9e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain AAA_8 PF12780.2 EAU81472.2 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 RhgB_N PF09284.5 EAU81474.2 - 1.3e-88 296.5 1.2 2e-88 295.9 0.8 1.2 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EAU81474.2 - 4.6e-46 156.5 0.0 1.3e-45 155.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EAU81474.2 - 2.9e-16 59.3 0.6 7.3e-16 58.0 0.4 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EAU81474.2 - 0.00028 20.8 2.4 0.00088 19.2 1.7 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Cyclin_N PF00134.18 EAU81475.2 - 2.8e-40 136.8 0.2 1.1e-39 134.9 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAU81475.2 - 1.9e-23 82.5 0.0 4.7e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain p450 PF00067.17 EAU81476.2 - 2.9e-66 223.9 0.0 1.1e-65 222.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Proteasome PF00227.21 EAU81477.1 - 4.6e-48 163.0 0.2 7.2e-48 162.4 0.1 1.3 2 0 0 2 2 2 1 Proteasome subunit Pr_beta_C PF12465.3 EAU81477.1 - 5.4e-13 47.9 0.2 1e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Arm PF00514.18 EAU81478.1 - 2.3e-08 33.5 1.2 0.6 10.0 0.0 6.5 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAU81478.1 - 7.9e-05 22.8 20.5 0.034 14.4 0.1 8.1 7 2 1 8 8 8 3 HEAT repeats Adaptin_N PF01602.15 EAU81478.1 - 0.00032 19.1 0.8 0.13 10.6 0.0 3.9 4 0 0 4 4 4 1 Adaptin N terminal region HEAT PF02985.17 EAU81478.1 - 0.0015 18.4 13.2 0.05 13.7 0.0 7.5 8 0 0 8 8 8 1 HEAT repeat Prenylcys_lyase PF07156.9 EAU81478.1 - 0.28 10.0 0.0 0.47 9.2 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase Ribosomal_L28e PF01778.12 EAU81481.2 - 1e-31 109.7 1.7 1e-31 109.7 1.2 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EAU81481.2 - 4.9e-19 68.2 28.1 4.9e-19 68.2 19.5 3.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EAU81481.2 - 0.00017 20.8 23.4 0.00024 20.3 16.2 1.2 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.8 EAU81481.2 - 0.0014 18.6 14.8 0.0018 18.2 10.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EAU81481.2 - 0.12 10.2 33.9 0.17 9.7 23.5 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EAU81481.2 - 0.29 10.3 21.4 0.39 9.9 14.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIF_alpha PF05793.7 EAU81481.2 - 0.52 8.6 35.5 0.74 8.1 24.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Na_trans_assoc PF06512.8 EAU81481.2 - 2.2 8.1 22.0 4.2 7.2 15.3 1.5 1 1 0 1 1 1 0 Sodium ion transport-associated Hid1 PF12722.2 EAU81481.2 - 5.8 4.4 8.4 8.5 3.9 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein S1-P1_nuclease PF02265.11 EAU81483.1 - 1.5e-38 132.8 0.8 1.3e-34 119.9 0.1 3.2 2 1 0 2 2 2 2 S1/P1 Nuclease Aminotran_1_2 PF00155.16 EAU81484.1 - 1.2e-50 172.5 0.0 1.5e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 EAU81486.2 - 2.1e-60 198.6 20.7 1.4e-15 56.4 1.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat DPPIV_N PF00930.16 EAU81486.2 - 9.1e-05 21.1 2.2 0.065 11.8 0.0 2.9 3 1 0 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Apc4_WD40 PF12894.2 EAU81486.2 - 0.00023 20.6 0.0 4.8 6.7 0.0 4.9 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EAU81486.2 - 0.00042 20.0 0.8 0.38 10.4 0.0 2.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EAU81486.2 - 0.00094 18.0 0.3 0.37 9.4 0.1 3.8 1 1 2 3 3 3 1 Nup133 N terminal like PD40 PF07676.7 EAU81486.2 - 0.011 15.3 0.6 0.9 9.2 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EAU81486.2 - 0.017 14.8 2.5 1.5 8.5 0.0 2.8 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Lactonase PF10282.4 EAU81486.2 - 0.021 13.9 0.1 4.9 6.1 0.0 2.9 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller IKI3 PF04762.7 EAU81486.2 - 0.53 8.0 6.2 12 3.5 0.2 3.0 2 1 1 3 3 3 0 IKI3 family Snurportin1 PF11538.3 EAU81487.2 - 0.021 14.6 3.1 0.021 14.6 2.2 2.0 2 0 0 2 2 2 0 Snurportin1 DUF2408 PF10303.4 EAU81488.2 - 0.05 13.7 2.2 0.67 10.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF2746 PF10874.3 EAU81488.2 - 0.073 13.2 0.3 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) DASH_Dad3 PF08656.5 EAU81488.2 - 0.31 10.7 1.3 1.2 8.8 0.0 2.2 3 0 0 3 3 3 0 DASH complex subunit Dad3 DUF4510 PF14971.1 EAU81488.2 - 0.49 10.5 2.3 13 5.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Zein-binding PF04576.10 EAU81488.2 - 2.8 8.1 5.9 1.1 9.3 0.3 2.2 1 1 0 2 2 2 0 Zein-binding 2-Hacid_dh_C PF02826.14 EAU81489.2 - 6.8e-38 129.5 0.0 1.2e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sin3_corepress PF08295.7 EAU81489.2 - 6.9e-35 118.8 0.2 2.3e-34 117.1 0.1 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 EAU81489.2 - 9.2e-31 105.2 4.7 4.5e-16 58.1 0.0 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat 2-Hacid_dh PF00389.25 EAU81489.2 - 2.4e-26 91.7 0.0 5.3e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EAU81489.2 - 0.0065 16.8 0.0 0.02 15.2 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Cyclin_N PF00134.18 EAU81490.1 - 1.2e-44 150.8 1.3 3.3e-44 149.5 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAU81490.1 - 7.8e-25 87.1 0.0 1.5e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_S15 PF00312.17 EAU81491.1 - 2.8e-14 52.6 0.5 2.8e-14 52.6 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 ATP_sub_h PF10775.4 EAU81491.1 - 0.062 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 ATP synthase complex subunit h DNA_mis_repair PF01119.14 EAU81492.2 - 4.3e-30 103.6 0.1 8.4e-30 102.6 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EAU81492.2 - 7.6e-15 54.7 0.2 3.2e-14 52.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAU81492.2 - 2.2e-10 40.2 0.0 4.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOR2-PAG1_N PF14222.1 EAU81493.2 - 4.8e-136 454.6 0.1 1e-134 450.2 0.0 2.2 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EAU81493.2 - 2.2e-83 280.0 1.4 4.7e-83 278.9 0.9 1.6 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EAU81493.2 - 5.5e-11 40.8 1.0 4.3e-08 31.2 0.3 2.4 3 0 0 3 3 3 2 Cell morphogenesis central region PC_rep PF01851.17 EAU81494.2 - 2.8e-21 74.5 24.6 6e-05 23.0 0.3 8.9 8 0 0 8 8 8 6 Proteasome/cyclosome repeat Adaptin_N PF01602.15 EAU81494.2 - 0.072 11.4 0.0 0.49 8.6 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region TPR_5 PF12688.2 EAU81494.2 - 0.14 12.1 0.9 24 4.9 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat CBS PF00571.23 EAU81495.1 - 1.7e-06 27.6 0.0 5.2e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 CBS domain Adaptin_binding PF10199.4 EAU81502.2 - 0.006 16.8 20.5 0.062 13.5 0.0 2.4 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 SAPS PF04499.10 EAU81502.2 - 0.16 10.5 4.1 0.21 10.1 2.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 EAU81502.2 - 0.45 8.3 27.6 0.67 7.7 19.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EAU81502.2 - 0.86 7.5 17.1 1.3 6.9 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EAU81502.2 - 1.6 7.0 26.9 2.4 6.5 18.7 1.2 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EAU81502.2 - 3.7 5.1 6.8 5 4.7 4.7 1.1 1 0 0 1 1 1 0 Ycf1 Orthopox_F8 PF05886.6 EAU81504.2 - 0.14 12.0 1.4 0.34 10.7 1.0 1.7 1 0 0 1 1 1 0 Orthopoxvirus F8 protein F-box-like PF12937.2 EAU81505.2 - 8.5e-05 22.1 6.6 0.0002 20.9 4.6 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU81505.2 - 0.00032 20.2 3.0 0.94 9.1 0.0 4.9 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.28 EAU81505.2 - 0.023 14.3 3.3 0.069 12.8 2.3 1.9 1 0 0 1 1 1 0 F-box domain LRR_7 PF13504.1 EAU81505.2 - 1.1 9.7 5.3 1.5e+02 3.3 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat RRM_1 PF00076.17 EAU81508.2 - 8e-17 60.6 0.0 3.2e-11 42.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU81508.2 - 1.8e-14 53.4 0.0 1.1e-08 34.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU81508.2 - 1.2e-08 34.6 0.0 2.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 EAU81509.2 - 3.6e-13 49.7 0.0 1.8e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Metallophos PF00149.23 EAU81511.2 - 6.8e-10 38.6 0.3 5.5e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU81511.2 - 1.4e-06 28.2 0.0 3.2e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mito_carr PF00153.22 EAU81512.2 - 2.2e-56 187.5 1.0 1.3e-20 72.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Nol1_Nop2_Fmu PF01189.12 EAU81513.1 - 7.2e-27 94.4 0.0 2.7e-25 89.3 0.0 2.4 2 0 0 2 2 2 1 NOL1/NOP2/sun family FtsJ PF01728.14 EAU81513.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase LRR_4 PF12799.2 EAU81514.1 - 0.0057 16.2 4.6 7.6 6.2 0.0 5.0 3 1 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU81514.1 - 1.2 8.8 11.0 7.2 6.4 1.1 4.1 4 1 0 4 4 4 0 Leucine rich repeat Pmp3 PF01679.12 EAU81515.1 - 2.6e-23 81.4 8.4 3e-23 81.2 5.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.6 EAU81515.1 - 0.0075 16.2 1.5 0.0091 16.0 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1056) Kinetochor_Ybp2 PF08568.5 EAU81517.1 - 2.4e-20 72.3 0.8 5.9e-19 67.7 0.2 2.3 1 1 1 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin F-box-like PF12937.2 EAU81523.1 - 0.011 15.4 0.2 0.011 15.4 0.2 2.2 3 0 0 3 3 3 0 F-box-like CH PF00307.26 EAU81525.2 - 9.7e-66 218.6 0.0 1.9e-20 72.9 0.0 4.8 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EAU81525.2 - 7.7e-06 25.4 0.0 1.7 8.3 0.0 3.6 3 0 0 3 3 3 3 CAMSAP CH domain EF-hand_7 PF13499.1 EAU81525.2 - 0.00028 20.9 0.0 0.00096 19.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair Complex1_49kDa PF00346.14 EAU81525.2 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Herpes_PAP PF03325.8 EAU81525.2 - 0.02 14.4 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein OPT PF03169.10 EAU81526.2 - 3.4e-172 574.1 60.3 5e-171 570.2 41.8 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF4381 PF14316.1 EAU81526.2 - 2.5 8.2 4.1 32 4.6 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) p450 PF00067.17 EAU81537.2 - 1.4e-14 53.5 0.0 2.3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 EAU81538.2 - 2.9e-50 168.5 3.2 4.9e-13 49.2 0.0 5.9 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EAU81538.2 - 2.3e-48 159.6 7.9 2e-07 30.4 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EAU81538.2 - 5e-41 137.7 11.9 1.7e-11 43.9 0.1 6.8 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU81538.2 - 1.3e-37 127.5 10.4 4.6e-08 33.3 0.0 8.6 1 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU81538.2 - 1.4e-35 117.7 4.5 0.001 19.1 0.0 10.1 9 0 0 9 9 9 7 Ankyrin repeat NACHT PF05729.7 EAU81538.2 - 9.1e-06 25.4 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EAU81538.2 - 4.7e-05 22.3 0.1 8.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NapD PF03927.8 EAU81538.2 - 0.00058 19.6 0.1 1.1 9.1 0.0 3.4 2 1 1 3 3 3 2 NapD protein DUF2075 PF09848.4 EAU81538.2 - 0.018 14.0 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EAU81538.2 - 0.088 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Acetyltransf_3 PF13302.1 EAU81539.1 - 2.3e-12 47.2 0.0 3.9e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU81539.1 - 0.0072 16.3 0.0 0.13 12.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family SEP PF08059.8 EAU81540.2 - 5.6e-19 68.2 0.0 1.2e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EAU81540.2 - 2.6e-17 62.6 0.1 4.3e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain Acetyltransf_3 PF13302.1 EAU81541.1 - 1.6e-12 47.7 0.0 5.2e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU81541.1 - 0.017 15.1 0.0 0.7 9.9 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Diphthamide_syn PF01866.12 EAU81544.2 - 5.1e-64 216.4 0.0 1.6e-39 135.9 0.0 2.1 1 1 0 2 2 2 2 Putative diphthamide synthesis protein Aldo_ket_red PF00248.16 EAU81547.1 - 7.5e-74 248.0 0.0 8.5e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cpn60_TCP1 PF00118.19 EAU81548.1 - 4.4e-117 391.6 5.0 5e-117 391.4 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rubella_E2 PF05749.6 EAU81548.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 LRR_4 PF12799.2 EAU81549.2 - 0.016 14.8 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Polysacc_deac_1 PF01522.16 EAU81555.2 - 2.3e-24 85.4 0.0 3.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Cys_Met_Meta_PP PF01053.15 EAU81556.1 - 1.2e-106 356.3 0.0 2.2e-80 269.8 0.0 2.6 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EAU81556.1 - 0.00068 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EAU81556.1 - 0.11 10.7 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Pro_isomerase PF00160.16 EAU81559.1 - 1.6e-48 164.8 0.1 2.7e-48 164.0 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CHRD PF07452.7 EAU81559.1 - 0.002 18.7 0.1 0.004 17.7 0.1 1.4 1 0 0 1 1 1 1 CHRD domain Ead_Ea22 PF13935.1 EAU81561.1 - 0.061 13.6 1.7 0.14 12.4 1.2 1.8 1 1 0 1 1 1 0 Ead/Ea22-like protein Zip PF02535.17 EAU81562.1 - 0.14 11.0 3.4 0.18 10.7 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EAU81562.1 - 0.59 9.4 11.3 0.74 9.1 7.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region polyprenyl_synt PF00348.12 EAU81564.1 - 3.4e-63 212.9 0.0 1.9e-44 151.4 0.0 3.0 3 0 0 3 3 3 3 Polyprenyl synthetase Metal_resist PF13801.1 EAU81564.1 - 0.00055 19.9 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 Heavy-metal resistance DUF1191 PF06697.7 EAU81567.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EAU81567.1 - 0.048 14.0 0.5 0.084 13.2 0.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain stn_TNFRSF12A PF12191.3 EAU81567.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain WBP-1 PF11669.3 EAU81569.2 - 0.082 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 COX7C PF02935.11 EAU81571.2 - 8.9e-13 47.8 1.1 1.1e-12 47.4 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc COX7C PF02935.11 EAU81572.1 - 5.8e-13 48.4 0.9 7.1e-13 48.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc FA_desaturase PF00487.19 EAU81573.1 - 9.3e-26 90.8 26.6 9.3e-26 90.8 18.4 1.7 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 EAU81573.1 - 0.00033 20.6 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.19 EAU81574.2 - 3.9e-27 95.3 25.4 7.9e-27 94.3 17.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EAU81574.2 - 0.0033 17.4 0.0 0.0065 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) BolA PF01722.13 EAU81577.2 - 3.9e-22 77.9 0.1 4.5e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein MobB PF03205.9 EAU81577.2 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATPgrasp_Ter PF15632.1 EAU81578.2 - 5.5e-15 54.9 0.0 1.4e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EAU81578.2 - 2.6e-14 53.3 0.0 6.4e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EAU81578.2 - 4e-10 39.7 0.0 6.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain DUF4066 PF13278.1 EAU81579.1 - 3.3e-34 117.5 0.0 4e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAU81579.1 - 2.2e-12 46.6 0.0 3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family BTB PF00651.26 EAU81580.2 - 0.00075 19.4 0.0 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Ricin_B_lectin PF00652.17 EAU81581.1 - 4.8e-19 68.5 10.9 4.8e-19 68.5 7.6 1.7 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU81581.1 - 7e-13 48.8 10.4 1.7e-08 34.7 1.1 3.0 1 1 3 4 4 4 3 Ricin-type beta-trefoil lectin domain-like ET PF01684.11 EAU81581.1 - 0.16 12.0 3.7 0.18 11.8 0.8 2.2 1 1 0 2 2 2 0 ET module Methyltransf_16 PF10294.4 EAU81582.2 - 1.6e-20 73.2 0.0 2.1e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EAU81582.2 - 0.0036 17.0 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU81582.2 - 0.0044 17.5 0.0 0.0071 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAU81582.2 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EAU81582.2 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cu_bind_like PF02298.12 EAU81583.2 - 0.0028 17.4 3.4 0.064 13.0 0.5 3.1 2 1 0 2 2 2 2 Plastocyanin-like domain Kelch_3 PF13415.1 EAU81585.2 - 1.1e-24 85.9 7.1 4.5e-07 29.8 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain DUF4110 PF13422.1 EAU81585.2 - 1.1e-24 86.0 0.2 1.1e-24 86.0 0.1 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EAU81585.2 - 1.9e-20 72.3 12.8 1.2e-06 28.1 0.1 5.3 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EAU81585.2 - 2.3e-15 56.0 3.8 1.3e-05 25.1 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EAU81585.2 - 2.7e-12 46.0 6.0 4.4e-06 26.1 0.1 4.1 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EAU81585.2 - 1e-09 37.7 10.3 2.4e-06 27.0 0.1 3.8 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EAU81585.2 - 1.1e-09 38.0 7.1 6.9e-05 22.6 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Med3 PF11593.3 EAU81586.1 - 0.54 9.4 14.2 0.69 9.0 9.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_16 PF00722.16 EAU81587.2 - 1.4e-06 27.7 0.0 3.3e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 EAU81588.1 - 2e-06 27.2 0.0 4e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 EAU81589.2 - 5.1e-07 29.1 0.0 1.3e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 EAU81590.1 - 4.2e-07 29.4 0.0 1.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pkinase PF00069.20 EAU81592.2 - 0.00019 20.6 0.0 0.00044 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU81592.2 - 0.002 17.8 0.0 0.0058 16.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EAU81592.2 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PIN_4 PF13638.1 EAU81595.1 - 2.2e-07 31.0 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 PIN domain Pkinase PF00069.20 EAU81596.2 - 0.00038 19.6 0.0 0.00061 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Shisa PF13908.1 EAU81597.2 - 0.45 10.6 3.3 0.58 10.3 0.0 2.6 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF1183 PF06682.7 EAU81597.2 - 1.5 8.3 0.0 1.5 8.3 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1183) Vpu PF00558.14 EAU81597.2 - 3 7.4 5.7 17 5.0 0.1 3.4 4 0 0 4 4 4 0 Vpu protein MAD PF05557.8 EAU81598.1 - 3.4e-38 131.2 68.3 5.7e-38 130.5 47.3 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein ATP-grasp_3 PF02655.9 EAU81598.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain Reo_sigmaC PF04582.7 EAU81598.1 - 2.8 7.0 24.8 0.25 10.5 2.3 3.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Filament PF00038.16 EAU81598.1 - 3.6 6.9 89.1 0.18 11.2 25.1 5.8 2 1 3 5 5 5 0 Intermediate filament protein YojJ PF10372.4 EAU81598.1 - 4.9 7.1 8.0 4.1 7.3 0.5 3.5 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus DTHCT PF08070.6 EAU81599.2 - 0.025 15.2 10.6 0.081 13.5 7.3 1.9 1 0 0 1 1 1 0 DTHCT (NUC029) region Ribosomal_60s PF00428.14 EAU81599.2 - 0.5 10.7 6.5 0.061 13.7 1.1 2.0 1 1 1 2 2 2 0 60s Acidic ribosomal protein Lactamase_B_2 PF12706.2 EAU81600.1 - 2.6e-41 141.3 0.1 3.7e-41 140.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAU81600.1 - 3.3e-09 36.6 0.0 2.6e-06 27.2 0.0 2.9 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAU81600.1 - 0.0085 15.7 0.1 0.03 13.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily GTP_EFTU PF00009.22 EAU81604.2 - 4.9e-50 169.5 0.0 6.8e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAU81604.2 - 1.4e-17 63.2 0.0 3.9e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EAU81604.2 - 2.8e-09 36.9 1.5 7.2e-09 35.6 1.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAU81604.2 - 2.7e-07 30.5 0.1 6.5e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAU81604.2 - 0.00039 20.8 0.0 0.0013 19.2 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EAU81604.2 - 0.026 13.7 0.1 1.9 7.6 0.1 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EAU81604.2 - 0.03 14.1 0.0 1.3 8.8 0.0 2.6 2 1 0 3 3 3 0 Dynamin family FeoB_N PF02421.13 EAU81604.2 - 0.083 12.1 0.0 1.1 8.5 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Pkinase PF00069.20 EAU81605.2 - 3.1e-07 29.8 0.0 5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU81605.2 - 0.021 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.2 EAU81606.1 - 1.8e-15 57.0 0.0 4.1e-12 46.2 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAU81606.1 - 3.4e-14 51.8 0.5 6.1e-06 25.7 0.2 4.6 4 1 1 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EAU81606.1 - 2.9e-13 48.6 0.0 0.00015 21.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EAU81606.1 - 1.7e-12 47.4 0.2 9.1e-06 26.0 0.0 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU81606.1 - 4e-09 36.4 1.1 0.00024 21.2 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Glyco_hydro_88 PF07470.8 EAU81609.2 - 3.1e-16 59.3 0.5 4.1e-16 58.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 F-box-like PF12937.2 EAU81610.1 - 1.6e-11 43.7 1.1 3.5e-11 42.6 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU81610.1 - 0.055 13.1 1.3 0.75 9.5 0.9 2.7 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EAU81611.1 - 0.0002 21.0 0.3 0.0004 20.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like Cwf_Cwc_15 PF04889.7 EAU81611.1 - 0.16 11.6 0.3 0.25 11.0 0.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2 PF00096.21 EAU81612.2 - 6.8e-11 41.8 7.7 1e-06 28.6 0.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU81612.2 - 2.1e-07 30.8 12.2 7.1e-06 26.0 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU81612.2 - 7e-07 29.1 7.2 0.00011 22.2 0.4 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU81612.2 - 0.00055 19.9 3.5 0.049 13.7 0.1 2.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAU81612.2 - 0.011 15.5 1.4 0.042 13.7 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EAU81612.2 - 0.017 15.3 5.3 0.12 12.6 0.1 3.2 3 1 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAU81612.2 - 0.033 14.2 0.4 0.059 13.4 0.3 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EAU81612.2 - 0.079 12.7 3.1 0.51 10.1 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger Sugar_tr PF00083.19 EAU81614.1 - 7.1e-92 308.3 23.9 8.5e-92 308.0 16.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU81614.1 - 7.2e-18 64.4 39.8 4.7e-12 45.3 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HA2 PF04408.18 EAU81615.1 - 2.7e-27 94.7 0.1 6e-27 93.6 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAU81615.1 - 3.9e-26 91.1 0.0 2.9e-25 88.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAU81615.1 - 1.3e-10 40.9 0.0 3.3e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU81615.1 - 1.1e-07 31.4 0.2 2.5e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 EAU81615.1 - 0.00011 21.6 0.4 0.00046 19.6 0.3 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EAU81615.1 - 0.00046 20.3 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EAU81615.1 - 0.003 16.4 0.0 0.0063 15.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EAU81615.1 - 0.026 14.3 0.1 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EAU81615.1 - 0.035 14.4 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EAU81615.1 - 0.037 13.6 0.1 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EAU81615.1 - 0.042 13.0 0.0 0.15 11.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EAU81615.1 - 0.047 12.7 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 KaiC Flavi_DEAD PF07652.9 EAU81615.1 - 0.047 13.4 0.2 0.098 12.4 0.2 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 EAU81616.1 - 2.5e-59 200.8 0.0 5.4e-59 199.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DnaJ-X PF14308.1 EAU81617.2 - 3.2e-54 183.3 0.0 3.2e-54 183.3 0.0 2.5 4 0 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.26 EAU81617.2 - 2.1e-26 91.4 0.3 5.1e-26 90.1 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Rtf2 PF04641.7 EAU81617.2 - 0.014 14.5 0.6 0.032 13.4 0.4 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2514 PF10721.4 EAU81617.2 - 0.084 12.5 6.7 0.26 10.9 4.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) PEX11 PF05648.9 EAU81617.2 - 0.2 10.8 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF1441 PF07278.6 EAU81617.2 - 0.8 9.3 4.4 0.78 9.3 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) DUF3391 PF11871.3 EAU81617.2 - 1.4 9.1 8.4 5.5 7.2 2.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) MMR_HSR1 PF01926.18 EAU81619.1 - 3.9e-10 39.7 0.0 7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU81619.1 - 1.1e-09 37.7 0.0 1.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAU81619.1 - 4.1e-07 29.3 0.0 7.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 EAU81619.1 - 4.9e-07 29.2 0.0 2.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EAU81619.1 - 3.2e-05 24.4 0.0 6.1e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EAU81619.1 - 0.00022 21.5 0.0 0.00044 20.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EAU81619.1 - 0.00027 20.9 0.1 0.00049 20.1 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain Dynamin_N PF00350.18 EAU81619.1 - 0.00044 20.1 0.1 0.014 15.1 0.1 2.4 1 1 1 2 2 2 1 Dynamin family IIGP PF05049.8 EAU81619.1 - 0.0018 17.1 0.0 0.0039 16.0 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) DUF815 PF05673.8 EAU81619.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EAU81619.1 - 0.0025 17.9 0.0 0.0046 17.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EAU81619.1 - 0.0025 17.9 0.1 0.0074 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Guanylate_kin PF00625.16 EAU81619.1 - 0.009 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Guanylate kinase Arf PF00025.16 EAU81619.1 - 0.01 15.0 0.0 0.088 12.0 0.0 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.5 EAU81619.1 - 0.012 14.8 0.0 0.024 13.8 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EAU81619.1 - 0.013 14.9 0.0 0.043 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain FeoB_N PF02421.13 EAU81619.1 - 0.029 13.6 0.0 0.086 12.1 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EAU81619.1 - 0.031 13.8 0.0 0.086 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAU81619.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EAU81619.1 - 0.05 12.7 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-ZPR1 PF03367.8 EAU81619.1 - 0.056 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 ZPR1 zinc-finger domain AAA PF00004.24 EAU81619.1 - 0.064 13.4 0.0 0.59 10.3 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EAU81619.1 - 0.073 13.3 0.1 0.2 11.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EAU81619.1 - 0.077 12.3 0.3 2.1 7.6 0.0 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain Septin PF00735.13 EAU81619.1 - 0.083 11.8 0.0 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.18 EAU81620.2 - 1e-07 31.9 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU81620.2 - 0.00029 20.0 0.0 0.00044 19.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAU81620.2 - 0.00036 19.7 0.1 0.00061 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAU81620.2 - 0.0087 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EAU81620.2 - 0.01 16.1 0.1 0.025 14.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Ras PF00071.17 EAU81620.2 - 0.018 14.4 0.2 0.48 9.7 0.2 2.5 1 1 0 1 1 1 0 Ras family DUF815 PF05673.8 EAU81620.2 - 0.055 12.3 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EAU81620.2 - 0.077 13.1 0.1 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAU81620.2 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EAU81620.2 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase OmpH PF03938.9 EAU81620.2 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Septin PF00735.13 EAU81622.1 - 7.1e-114 379.5 0.4 1e-113 379.0 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EAU81622.1 - 2.4e-07 30.7 0.0 4.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAU81622.1 - 8.5e-07 28.2 0.0 2e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EAU81622.1 - 4.8e-06 26.1 0.0 0.00028 20.3 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EAU81622.1 - 0.00053 19.1 0.0 0.0013 17.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EAU81622.1 - 0.00082 19.8 0.3 0.0021 18.5 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EAU81622.1 - 0.00097 19.2 0.6 0.014 15.5 0.0 2.8 3 1 0 3 3 3 1 AAA domain Ras PF00071.17 EAU81622.1 - 0.0015 17.9 0.2 0.0058 16.0 0.2 2.0 1 1 0 1 1 1 1 Ras family PduV-EutP PF10662.4 EAU81622.1 - 0.0023 17.4 0.9 0.071 12.6 0.1 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EAU81622.1 - 0.0034 17.2 5.5 0.36 10.6 0.1 3.0 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 EAU81622.1 - 0.0057 16.9 0.1 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EAU81622.1 - 0.0058 16.6 0.5 0.048 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EAU81622.1 - 0.01 15.7 0.4 0.03 14.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EAU81622.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EAU81622.1 - 0.023 14.3 0.0 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EAU81622.1 - 0.024 14.2 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU81622.1 - 0.043 13.4 0.0 0.093 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EAU81622.1 - 0.051 12.4 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Bac_DnaA PF00308.13 EAU81622.1 - 0.061 12.9 3.3 2.1 7.9 0.2 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_33 PF13671.1 EAU81622.1 - 0.069 13.0 0.0 0.22 11.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAU81622.1 - 0.073 12.7 2.2 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 EAU81622.1 - 0.093 11.6 0.3 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EAU81622.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EAU81622.1 - 0.14 11.6 1.0 0.35 10.3 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family F-box-like PF12937.2 EAU81623.1 - 1.1e-05 25.0 6.7 5.4e-05 22.8 2.0 3.2 3 1 0 3 3 3 1 F-box-like NIF PF03031.13 EAU81625.2 - 1.9e-15 56.8 0.0 3.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Adaptin_binding PF10199.4 EAU81625.2 - 0.0039 17.4 0.7 0.007 16.6 0.5 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF694 PF05107.7 EAU81625.2 - 0.91 8.6 4.9 1.4 8.1 3.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF694) DUF3337 PF11816.3 EAU81628.2 - 4.5e-33 115.0 3.7 6.5e-30 104.6 2.5 3.3 2 2 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EAU81628.2 - 5e-33 111.7 19.0 4.3e-08 32.7 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat RHD3 PF05879.7 EAU81628.2 - 0.39 8.5 0.4 0.55 8.0 0.3 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Peptidase_M48 PF01435.13 EAU81629.1 - 6.7e-25 87.9 0.0 1.3e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 EAU81629.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) NAD_binding_9 PF13454.1 EAU81630.1 - 4.7e-05 23.1 0.1 0.0003 20.6 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAU81630.1 - 0.0072 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1996 PF09362.5 EAU81631.2 - 1e-61 208.5 0.0 1.3e-59 201.7 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) HNH PF01844.18 EAU81632.1 - 0.00028 20.6 1.7 0.00054 19.7 1.2 1.5 1 0 0 1 1 1 1 HNH endonuclease DUF968 PF06147.6 EAU81632.1 - 0.0051 16.7 1.1 0.015 15.2 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF968) C1_1 PF00130.17 EAU81632.1 - 0.03 14.0 0.7 0.091 12.4 0.5 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3505 PF12013.3 EAU81632.1 - 2.7 8.2 6.8 0.18 12.0 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) CybS PF05328.7 EAU81634.1 - 2.1e-44 150.3 0.0 2.5e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 CybS Dynamin_M PF01031.15 EAU81635.1 - 2.8e-27 95.2 0.1 9.4e-27 93.5 0.1 1.7 1 1 1 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EAU81635.1 - 1.1e-21 77.3 0.0 3.9e-21 75.5 0.0 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 EAU81635.1 - 1.5e-09 37.6 0.3 5e-09 35.9 0.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAU81635.1 - 4.9e-07 29.7 0.1 1.1e-05 25.3 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAU81635.1 - 0.0022 18.4 0.0 0.017 15.6 0.0 2.5 3 0 0 3 3 3 1 Miro-like protein YopR_core PF09025.5 EAU81635.1 - 0.0036 17.3 0.1 0.0096 15.9 0.0 1.7 1 0 0 1 1 1 1 YopR Core AIG1 PF04548.11 EAU81635.1 - 0.0036 16.4 0.0 0.36 9.8 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.13 EAU81635.1 - 0.057 12.6 0.0 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Ank_2 PF12796.2 EAU81638.2 - 1.5e-158 515.5 16.1 6.3e-18 64.9 0.0 12.0 1 1 13 14 14 14 14 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU81638.2 - 7.8e-139 448.6 39.4 6.4e-11 42.1 0.1 18.6 2 1 17 19 19 19 18 Ankyrin repeats (many copies) Ank PF00023.25 EAU81638.2 - 2.7e-119 383.4 10.0 5.5e-06 25.9 0.0 20.1 20 0 0 20 20 19 18 Ankyrin repeat Ank_4 PF13637.1 EAU81638.2 - 7.5e-107 348.0 7.1 1.1e-11 44.9 0.0 16.7 5 3 13 18 18 18 17 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU81638.2 - 1e-88 282.2 0.0 6.4e-05 22.8 0.0 20.1 19 0 0 19 19 19 17 Ankyrin repeat NapD PF03927.8 EAU81638.2 - 3e-09 36.5 25.0 0.098 12.4 0.1 13.8 6 4 12 19 19 17 2 NapD protein NACHT PF05729.7 EAU81638.2 - 1.4e-06 28.0 0.1 3.6e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 NACHT domain SchA_CurD PF04486.7 EAU81638.2 - 2.8e-05 23.8 15.4 9.6 6.0 0.0 8.9 6 4 3 9 9 9 0 SchA/CurD like domain NTPase_1 PF03266.10 EAU81638.2 - 0.00046 19.9 1.4 0.82 9.3 0.0 5.1 5 1 0 5 5 5 1 NTPase AAA_22 PF13401.1 EAU81638.2 - 0.00057 20.0 0.0 0.0082 16.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain UPF0146 PF03686.8 EAU81638.2 - 0.0011 18.8 16.0 91 2.8 0.0 10.1 3 3 9 13 13 13 0 Uncharacterised protein family (UPF0146) DUF108 PF01958.13 EAU81638.2 - 0.0012 19.0 23.4 30 4.9 0.0 10.9 4 4 9 13 13 13 0 Domain of unknown function DUF108 HasA PF06438.7 EAU81638.2 - 0.006 15.9 1.7 1.6e+02 1.5 0.0 6.6 3 3 2 7 7 7 0 Heme-binding protein A (HasA) IF2_N PF04760.10 EAU81638.2 - 0.012 15.2 0.0 1.6e+02 2.0 0.0 7.1 12 0 0 12 12 11 0 Translation initiation factor IF-2, N-terminal region cobW PF02492.14 EAU81638.2 - 0.015 14.7 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain WHG PF13305.1 EAU81638.2 - 0.018 15.6 13.5 3.5 8.2 0.1 7.7 6 4 3 10 10 8 0 WHG domain AAA_19 PF13245.1 EAU81638.2 - 0.021 14.5 3.6 0.19 11.5 0.0 4.1 4 1 1 5 5 5 0 Part of AAA domain AAA_14 PF13173.1 EAU81638.2 - 0.023 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU81638.2 - 0.024 14.6 0.0 0.1 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain HAD_2 PF13419.1 EAU81638.2 - 0.05 13.8 5.2 85 3.3 0.0 6.2 3 2 6 9 9 9 0 Haloacid dehalogenase-like hydrolase NB-ARC PF00931.17 EAU81638.2 - 0.054 12.3 0.1 0.093 11.5 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EAU81638.2 - 0.066 14.0 0.4 0.69 10.7 0.1 2.9 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EAU81638.2 - 0.25 10.9 0.0 0.57 9.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF1070 PF06376.7 EAU81638.2 - 1.8 8.5 19.0 80 3.2 0.0 9.5 12 0 0 12 12 10 0 Protein of unknown function (DUF1070) Alba PF01918.16 EAU81639.2 - 0.0024 17.4 0.3 1 8.9 0.0 2.8 3 1 0 3 3 3 2 Alba Peptidase_C12 PF01088.16 EAU81640.1 - 1.1e-51 175.0 0.0 1.2e-44 152.1 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-ZPR1 PF03367.8 EAU81641.2 - 5e-101 334.6 0.4 4.3e-50 169.0 0.0 3.1 2 1 0 2 2 2 2 ZPR1 zinc-finger domain UPF0547 PF10571.4 EAU81641.2 - 0.01 15.5 3.4 3.4 7.4 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 HypA PF01155.14 EAU81641.2 - 0.036 13.7 1.2 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FpoO PF10621.4 EAU81641.2 - 0.12 12.4 0.3 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-ribbon_3 PF13248.1 EAU81641.2 - 0.18 11.0 3.2 2.2 7.5 0.6 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EAU81641.2 - 0.71 9.8 6.2 32 4.5 0.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain DZR PF12773.2 EAU81641.2 - 0.91 9.3 4.5 8.4 6.3 0.1 2.9 2 1 0 2 2 2 0 Double zinc ribbon Abhydrolase_3 PF07859.8 EAU81642.2 - 7.7e-15 55.0 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU81642.2 - 3.1e-13 49.1 0.0 4.9e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAU81642.2 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family RVT_3 PF13456.1 EAU81643.1 - 8.1e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Tup_N PF08581.5 EAU81643.1 - 0.0088 16.2 2.0 0.016 15.3 1.4 1.4 1 0 0 1 1 1 1 Tup N-terminal FATC PF02260.15 EAU81643.1 - 0.15 11.5 1.1 0.29 10.6 0.2 1.9 2 0 0 2 2 2 0 FATC domain HR1 PF02185.11 EAU81643.1 - 0.22 11.2 2.5 0.2 11.4 0.6 1.8 2 0 0 2 2 2 0 Hr1 repeat Acyl_transf_3 PF01757.17 EAU81647.2 - 7.3e-09 34.9 29.4 9.4e-09 34.5 20.4 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF4614 PF15391.1 EAU81648.1 - 0.7 9.6 5.2 0.9 9.2 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) TFIIS_M PF07500.9 EAU81649.1 - 1.2e-32 112.3 0.9 2.2e-32 111.5 0.2 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EAU81649.1 - 1.6e-17 62.7 10.0 2.6e-17 62.1 6.9 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EAU81649.1 - 1e-15 56.9 0.9 1.9e-15 56.0 0.6 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Calpain_inhib PF00748.14 EAU81649.1 - 5.2 7.4 10.2 1.6 9.1 1.1 2.4 1 1 0 2 2 2 0 Calpain inhibitor Baculo_LEF5_C PF11792.3 EAU81649.1 - 6.1 6.3 6.7 0.6 9.5 0.4 2.2 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Renin_r PF07850.9 EAU81653.2 - 1 9.7 0.0 1 9.7 0.0 2.9 3 0 0 3 3 3 0 Renin receptor-like protein Glyco_hydro_88 PF07470.8 EAU81654.1 - 2.2e-21 76.2 0.0 3.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DicB PF05358.6 EAU81654.1 - 0.077 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 DicB protein DUF3292 PF11696.3 EAU81655.2 - 0.11 10.3 0.0 0.22 9.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Redoxin PF08534.5 EAU81656.1 - 2.2e-26 92.1 0.0 2.6e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EAU81656.1 - 1e-12 47.8 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family F-box-like PF12937.2 EAU81659.1 - 9.9e-06 25.1 0.4 2.1e-05 24.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU81659.1 - 0.0055 16.3 1.7 0.042 13.5 1.2 2.4 1 1 0 1 1 1 1 F-box domain MRG PF05712.8 EAU81662.2 - 5.5e-36 123.3 0.7 1.3e-26 92.7 0.0 2.2 2 0 0 2 2 2 2 MRG Tudor-knot PF11717.3 EAU81662.2 - 1.9e-09 37.0 0.1 3.5e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DSS1_SEM1 PF05160.8 EAU81663.1 - 5.9e-21 74.0 10.6 1.5e-20 72.7 7.3 1.6 1 1 0 1 1 1 1 DSS1/SEM1 family Ribosomal_S10 PF00338.17 EAU81665.2 - 3.2e-24 84.5 0.0 7e-24 83.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e EnY2 PF10163.4 EAU81666.2 - 1.9e-14 53.3 0.0 2.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 Mago_nashi PF02792.9 EAU81667.1 - 5.3e-72 240.1 0.2 6.1e-72 239.9 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF4436 PF14494.1 EAU81668.2 - 2.9e-09 36.6 0.3 4.1e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Tmpp129 PF10272.4 EAU81668.2 - 0.21 10.2 0.4 0.29 9.8 0.3 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF2793 PF10983.3 EAU81670.2 - 0.055 13.2 0.1 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Hydantoinase_A PF01968.13 EAU81671.2 - 1.1e-88 297.0 0.1 1.7e-88 296.4 0.1 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EAU81671.2 - 5.6e-54 182.3 0.1 3.3e-51 173.2 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Alph_Pro_TM PF09608.5 EAU81672.2 - 0.098 12.1 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Sdh_cyt PF01127.17 EAU81672.2 - 0.45 10.3 3.9 0.32 10.8 0.2 2.5 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF4131 PF13567.1 EAU81672.2 - 0.79 9.1 7.1 13 5.1 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) F-box PF00646.28 EAU81673.2 - 0.0043 16.6 0.0 0.012 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU81673.2 - 0.012 15.2 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.1 EAU81673.2 - 0.2 11.4 2.7 4.1 7.2 0.9 3.0 3 0 0 3 3 3 0 Leucine rich repeat Fungal_trans PF04082.13 EAU81674.2 - 6.7e-19 67.7 1.2 1.3e-18 66.8 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zw10 PF06248.8 EAU81676.1 - 0.053 11.6 4.9 0.045 11.8 2.5 1.4 1 1 0 1 1 1 0 Centromere/kinetochore Zw10 VSG_B PF13206.1 EAU81676.1 - 0.68 8.9 11.3 1 8.4 7.9 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Syntaxin PF00804.20 EAU81676.1 - 0.91 9.7 14.9 1.5e+02 2.6 10.3 3.0 1 1 0 1 1 1 0 Syntaxin Fib_alpha PF08702.5 EAU81676.1 - 2.6 8.1 8.4 7.6 6.6 3.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3416 PF11896.3 EAU81676.1 - 6.6 6.6 16.1 4.9 7.0 5.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3416) Glyco_hydro_61 PF03443.9 EAU81677.2 - 5e-40 137.6 0.0 6.3e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TMEM154 PF15102.1 EAU81678.2 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family GIDA PF01134.17 EAU81679.1 - 2.3e-153 510.7 0.0 3.3e-153 510.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EAU81679.1 - 6e-08 32.6 0.0 2e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 GidA associated domain 3 FAD_oxidored PF12831.2 EAU81679.1 - 2.3e-07 30.2 0.5 4.3e-07 29.3 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAU81679.1 - 1.2e-06 28.5 0.4 4.6e-06 26.6 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU81679.1 - 0.00016 20.6 1.7 0.0003 19.7 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EAU81679.1 - 0.0019 16.7 1.6 0.035 12.5 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 EAU81679.1 - 0.0076 15.1 3.5 0.037 12.9 0.8 2.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAU81679.1 - 0.019 15.3 0.6 0.045 14.1 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EAU81679.1 - 0.023 14.2 0.1 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EAU81679.1 - 0.071 12.1 0.2 0.14 11.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EAU81681.2 - 3.3e-12 46.6 0.0 3.8e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.15 EAU81681.2 - 3.1e-05 24.0 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EAU81681.2 - 6.2e-05 22.7 0.1 0.0002 21.0 0.0 1.8 1 1 1 2 2 2 1 KR domain Saccharop_dh PF03435.13 EAU81681.2 - 0.0023 17.0 0.1 0.0033 16.4 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EAU81681.2 - 0.0083 15.0 0.1 0.02 13.8 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EAU81681.2 - 0.06 12.7 0.0 0.084 12.2 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.10 EAU81681.2 - 0.09 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.1 EAU81681.2 - 0.092 13.0 0.1 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.20 EAU81682.2 - 3.7e-71 239.3 0.1 3e-70 236.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU81682.2 - 6.3e-35 120.4 0.1 5.8e-34 117.3 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EAU81682.2 - 1.1e-15 56.7 0.0 1.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EAU81682.2 - 3.1e-06 26.4 0.0 5.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU81682.2 - 0.00012 21.1 0.0 0.00028 19.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAU81682.2 - 0.0017 18.1 2.8 0.069 12.8 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1777 PF08648.7 EAU81682.2 - 0.0035 17.1 17.8 0.0035 17.1 12.4 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) WaaY PF06176.6 EAU81682.2 - 0.033 13.4 0.5 0.055 12.6 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EAU81682.2 - 0.16 11.2 0.0 0.42 9.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_Ag35 PF03286.9 EAU81682.2 - 5.2 6.5 11.5 3.5 7.0 1.4 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SPC12 PF06645.8 EAU81683.1 - 8.2e-26 89.6 0.3 9.8e-26 89.3 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Colicin_V PF02674.11 EAU81683.1 - 0.0062 16.3 0.8 0.0075 16.1 0.5 1.3 1 0 0 1 1 1 1 Colicin V production protein PIRT PF15099.1 EAU81683.1 - 0.027 13.6 0.2 0.032 13.4 0.2 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF4231 PF14015.1 EAU81683.1 - 5.3 7.0 6.4 39 4.2 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Sugar_tr PF00083.19 EAU81684.2 - 9.5e-82 274.9 22.7 2.1e-80 270.5 15.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU81684.2 - 5.2e-09 35.2 37.1 4e-05 22.5 11.6 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EAU81684.2 - 0.055 13.4 4.7 0.058 13.4 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) F-box-like PF12937.2 EAU81685.2 - 6.6e-06 25.7 0.2 1.8e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU81685.2 - 0.024 14.2 4.4 2.5 7.8 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF2359 PF10151.4 EAU81685.2 - 0.071 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) RAP1 PF07218.6 EAU81686.2 - 9.3 4.2 9.6 12 3.7 6.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 EAU81687.2 - 4.3e-71 239.1 0.0 4.8e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU81687.2 - 2e-31 109.0 0.0 2.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU81687.2 - 0.0041 16.8 0.1 0.019 14.7 0.1 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EAU81687.2 - 0.026 13.3 0.0 0.061 12.1 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.1 EAU81687.2 - 0.036 13.0 0.0 0.078 11.9 0.0 1.5 1 1 1 2 2 2 0 Kinase-like ATP_bind_1 PF03029.12 EAU81688.1 - 7.7e-80 267.8 0.1 1.3e-79 267.0 0.0 1.4 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EAU81688.1 - 9.7e-06 25.1 0.1 0.00012 21.6 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EAU81688.1 - 0.0003 20.2 0.7 0.00094 18.6 0.2 2.1 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 EAU81688.1 - 0.0014 18.5 0.0 0.0038 17.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU81688.1 - 0.004 16.4 0.1 0.028 13.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B G-alpha PF00503.15 EAU81688.1 - 0.0046 15.6 2.7 0.051 12.2 0.0 2.4 3 0 0 3 3 3 1 G-protein alpha subunit AAA_33 PF13671.1 EAU81688.1 - 0.0047 16.8 0.1 0.015 15.1 0.0 1.9 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EAU81688.1 - 0.0049 15.6 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EAU81688.1 - 0.0073 15.7 0.9 0.039 13.3 0.6 1.9 1 1 0 1 1 1 1 AAA-like domain Zeta_toxin PF06414.7 EAU81688.1 - 0.0093 15.0 0.1 0.2 10.6 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 EAU81688.1 - 0.017 15.9 2.0 0.048 14.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAU81688.1 - 0.022 14.5 0.1 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF4611 PF15387.1 EAU81688.1 - 0.026 14.6 1.4 0.055 13.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NACHT PF05729.7 EAU81688.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EAU81688.1 - 0.034 13.6 0.1 4 6.8 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GrpE PF01025.14 EAU81688.1 - 0.046 13.2 2.4 8.5 5.8 0.0 2.2 1 1 1 2 2 2 0 GrpE AAA_24 PF13479.1 EAU81688.1 - 0.083 12.4 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EAU81688.1 - 0.086 12.9 0.0 0.29 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Adeno_IVa2 PF02456.10 EAU81688.1 - 0.1 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Arf PF00025.16 EAU81688.1 - 0.11 11.7 0.0 0.63 9.2 0.0 2.2 3 0 0 3 3 3 0 ADP-ribosylation factor family NB-ARC PF00931.17 EAU81688.1 - 0.15 10.8 0.1 0.44 9.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF258 PF03193.11 EAU81688.1 - 0.17 11.0 0.1 0.6 9.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SAD_SRA PF02182.12 EAU81689.1 - 4.4e-44 149.5 0.2 5.1e-44 149.2 0.1 1.0 1 0 0 1 1 1 1 SAD/SRA domain adh_short PF00106.20 EAU81690.1 - 2.4e-15 56.8 0.0 4.2e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU81690.1 - 6.4e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EAU81690.1 - 0.0014 17.5 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EAU81690.1 - 0.0055 16.8 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TGF_beta_GS PF08515.7 EAU81691.1 - 0.0002 20.5 0.1 61 3.0 0.0 5.2 5 0 0 5 5 5 0 Transforming growth factor beta type I GS-motif Peptidase_M57 PF12388.3 EAU81691.1 - 0.29 10.4 15.7 17 4.6 0.1 5.0 1 1 4 5 5 5 0 Dual-action HEIGH metallo-peptidase CD99L2 PF12301.3 EAU81691.1 - 4.6 6.8 49.8 2 8.1 1.4 5.4 1 1 4 5 5 5 0 CD99 antigen like protein 2 NACHT PF05729.7 EAU81692.2 - 2.5e-10 40.2 0.1 7.4e-09 35.4 0.0 3.0 4 0 0 4 4 4 1 NACHT domain AAA_16 PF13191.1 EAU81692.2 - 4.5e-05 23.5 2.1 0.0002 21.4 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAU81692.2 - 0.0045 17.1 0.0 0.021 14.9 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAU81692.2 - 0.046 13.3 0.5 0.098 12.2 0.3 1.5 1 0 0 1 1 1 0 AAA domain BTB PF00651.26 EAU81693.2 - 2.5e-13 49.9 0.0 7.2e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain HATPase_c_3 PF13589.1 EAU81693.2 - 0.00041 20.0 0.0 0.75 9.4 0.0 3.1 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF455 PF04305.9 EAU81694.2 - 2e-78 263.1 0.0 3e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 EAU81694.2 - 8.8e-08 31.6 0.1 1.9e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EAU81694.2 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain Arabinose_Iso_C PF11762.3 EAU81694.2 - 0.1 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 L-arabinose isomerase C-terminal domain TMEM51 PF15345.1 EAU81695.2 - 0.0016 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Rifin_STEVOR PF02009.11 EAU81695.2 - 0.01 15.5 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF912 PF06024.7 EAU81695.2 - 0.047 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 EAU81695.2 - 0.1 13.0 0.1 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1708 PF08101.6 EAU81697.1 - 5.7e-14 51.7 0.0 1.3e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EAU81697.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain Dyp_perox PF04261.7 EAU81698.1 - 3.4e-08 32.5 0.2 5.2e-06 25.4 0.0 3.5 3 1 0 3 3 3 2 Dyp-type peroxidase family DUF2470 PF10615.4 EAU81699.1 - 5.3e-11 42.5 0.0 7.7e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 EAU81699.1 - 3.5e-09 36.4 0.5 6.3e-09 35.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) LRR_4 PF12799.2 EAU81700.2 - 0.014 15.0 4.5 0.062 12.9 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) NACHT PF05729.7 EAU81701.2 - 7.7e-14 51.6 0.1 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU81701.2 - 0.00018 21.5 0.2 0.0019 18.2 0.0 2.7 2 2 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EAU81701.2 - 0.00022 21.4 0.0 0.00065 19.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EAU81701.2 - 0.00054 18.9 0.1 0.068 12.0 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 EAU81701.2 - 0.0006 19.9 0.0 0.0021 18.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EAU81701.2 - 0.0014 17.7 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAU81701.2 - 0.033 14.9 0.0 0.099 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.11 EAU81701.2 - 0.048 12.4 0.0 0.095 11.4 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_33 PF13671.1 EAU81701.2 - 0.048 13.5 0.0 0.18 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAU81701.2 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 EAU81701.2 - 0.11 11.5 0.1 1.8 7.4 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.17 EAU81701.2 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 EAU81701.2 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 EAU81701.2 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EAU81701.2 - 0.22 11.8 0.0 0.52 10.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EAU81701.2 - 0.23 11.1 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 EAU81701.2 - 0.29 9.9 0.0 0.51 9.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF262 PF03235.9 EAU81702.2 - 1.2e-17 64.6 5.1 3.3e-17 63.2 3.6 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF262 Pkinase PF00069.20 EAU81703.2 - 3.5e-28 98.4 0.0 9.8e-28 97.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU81703.2 - 2.8e-09 36.4 0.0 0.035 13.1 0.0 3.8 4 0 0 4 4 4 3 Protein tyrosine kinase adh_short PF00106.20 EAU81704.1 - 3.3e-14 53.1 0.1 9.9e-14 51.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU81704.1 - 8.2e-08 32.3 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU81704.1 - 8.8e-07 28.7 0.0 3.9e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EAU81704.1 - 0.069 12.5 0.0 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4449 PF14613.1 EAU81705.1 - 1.3e-39 135.7 0.6 1.4e-38 132.3 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Apolipoprotein PF01442.13 EAU81705.1 - 0.018 14.5 27.4 0.19 11.1 0.2 5.0 3 1 1 5 5 5 0 Apolipoprotein A1/A4/E domain HisKA_3 PF07730.8 EAU81705.1 - 0.12 12.7 6.9 4.2 7.8 0.1 5.2 5 1 0 5 5 5 0 Histidine kinase Fib_alpha PF08702.5 EAU81705.1 - 2.3 8.3 11.8 0.5 10.4 0.1 3.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DUF4448 PF14610.1 EAU81706.1 - 0.0028 17.1 0.0 0.22 10.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) DUF4366 PF14283.1 EAU81706.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TMEM154 PF15102.1 EAU81706.1 - 0.027 14.1 0.0 0.074 12.7 0.0 1.7 2 0 0 2 2 2 0 TMEM154 protein family SKG6 PF08693.5 EAU81706.1 - 0.094 12.0 0.0 0.094 12.0 0.0 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PAT1 PF09770.4 EAU81707.2 - 0.69 8.0 16.6 0.72 8.0 11.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3_1 PF00018.23 EAU81708.2 - 3.1e-06 26.4 0.0 3.1e-06 26.4 0.0 3.0 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 EAU81708.2 - 6e-05 22.5 0.0 6e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EAU81708.2 - 0.0053 16.2 0.0 0.0053 16.2 0.0 2.0 3 0 0 3 3 3 1 Variant SH3 domain HemY_N PF07219.8 EAU81708.2 - 0.021 14.3 0.8 0.021 14.3 0.5 1.5 2 0 0 2 2 2 0 HemY protein N-terminus VirB3 PF05101.8 EAU81708.2 - 0.11 12.5 0.2 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Amnionless PF14828.1 EAU81708.2 - 0.16 10.4 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Amnionless BTB PF00651.26 EAU81709.2 - 5e-13 49.0 0.1 1.9e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 BTB/POZ domain HATPase_c_3 PF13589.1 EAU81709.2 - 0.00085 18.9 0.2 0.64 9.6 0.0 3.1 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAU81709.2 - 0.17 11.6 0.0 8.7 6.1 0.0 2.7 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phosphodiest PF01663.17 EAU81710.2 - 1.9e-11 43.9 0.4 3.4e-11 43.0 0.1 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EAU81710.2 - 1.1e-05 24.9 0.1 1.9e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EAU81710.2 - 0.0018 17.4 0.4 0.01 15.0 0.3 2.0 1 1 0 1 1 1 1 Sulfatase F-box PF00646.28 EAU81711.2 - 5.9e-07 28.9 1.1 1.4e-06 27.7 0.8 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU81711.2 - 4.8e-05 23.0 0.9 0.00014 21.4 0.6 1.9 1 0 0 1 1 1 1 F-box-like AA_permease_2 PF13520.1 EAU81715.2 - 3.7e-21 75.1 27.8 3.3e-12 45.6 9.7 2.0 2 0 0 2 2 2 2 Amino acid permease MIG-14_Wnt-bd PF06664.7 EAU81715.2 - 0.78 8.5 7.8 45 2.7 5.4 2.3 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Proteasome PF00227.21 EAU81717.2 - 3.8e-30 104.5 0.1 4.5e-30 104.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF1996 PF09362.5 EAU81719.2 - 3.7e-68 229.6 0.0 4.6e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Sugar_tr PF00083.19 EAU81720.2 - 2.2e-92 310.0 22.1 2.5e-92 309.8 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU81720.2 - 3.9e-21 75.1 25.4 1.1e-17 63.7 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAU81720.2 - 1.7e-05 23.4 2.6 1.7e-05 23.4 1.8 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein Rrf2 PF02082.15 EAU81721.1 - 0.17 12.0 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator Esterase_phd PF10503.4 EAU81722.1 - 3.8e-17 62.2 0.0 5.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EAU81722.1 - 3.5e-13 48.9 6.7 3.5e-13 48.9 4.6 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EAU81722.1 - 3.4e-08 32.9 0.2 5.6e-08 32.2 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAU81722.1 - 8.5e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU81722.1 - 8.9e-05 22.4 0.2 0.00019 21.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EAU81722.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EAU81722.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EAU81722.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EAU81722.1 - 0.024 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative esterase COesterase PF00135.23 EAU81722.1 - 0.045 12.4 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family DUF1264 PF06884.6 EAU81723.1 - 7.5e-72 240.3 0.0 1e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TPR_11 PF13414.1 EAU81724.1 - 9.8e-18 63.5 3.0 1.9e-16 59.4 0.7 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAU81724.1 - 2.5e-09 36.3 1.8 0.00016 21.3 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAU81724.1 - 2.4e-06 27.3 0.6 5e-06 26.2 0.4 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU81724.1 - 3.9e-06 27.3 8.1 0.00013 22.5 0.2 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU81724.1 - 9.9e-06 24.9 4.2 0.042 13.4 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU81724.1 - 8.1e-05 22.8 4.6 0.00012 22.3 0.5 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU81724.1 - 0.00073 19.5 2.2 2.2 8.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU81724.1 - 0.001 18.7 0.3 0.47 10.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-CCCH PF00642.19 EAU81724.1 - 0.0047 16.5 2.9 0.0047 16.5 2.0 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPR_14 PF13428.1 EAU81724.1 - 0.0088 16.6 2.6 0.19 12.4 0.6 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU81724.1 - 0.17 12.0 2.0 0.6 10.2 0.9 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EAU81724.1 - 0.65 9.9 8.8 0.048 13.6 1.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 EAU81725.1 - 1.8e-48 164.8 0.0 2e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lactamase_B PF00753.22 EAU81726.2 - 5.7e-22 78.3 1.9 7.6e-22 77.9 1.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAU81726.2 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_61 PF03443.9 EAU81728.2 - 9.1e-28 97.5 0.2 1.1e-27 97.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Actin PF00022.14 EAU81730.1 - 5.8e-151 502.3 0.0 6.5e-151 502.2 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 EAU81732.2 - 3e-106 355.1 0.0 2.7e-101 338.8 0.0 2.5 1 1 1 2 2 2 2 Actin F-box-like PF12937.2 EAU81733.1 - 0.031 13.9 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EAU81733.1 - 0.096 12.3 0.0 0.31 10.7 0.0 1.9 1 0 0 1 1 1 0 F-box domain Rick_17kDa_Anti PF05433.10 EAU81736.2 - 0.062 12.9 3.8 0.13 11.9 2.7 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain HECT PF00632.20 EAU81738.2 - 4.7e-79 265.8 0.0 2.1e-78 263.7 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EAU81738.2 - 0.01 15.3 0.8 0.036 13.6 0.5 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif KKLCAg1 PF15204.1 EAU81738.2 - 0.053 13.5 2.5 0.092 12.7 0.5 2.3 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 M-factor PF03855.8 EAU81739.1 - 0.085 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 M-factor CorA PF01544.13 EAU81740.2 - 0.0064 15.5 2.2 0.0064 15.5 1.5 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Med15 PF09606.5 EAU81741.2 - 0.097 10.8 4.9 0.11 10.6 3.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-MYND PF01753.13 EAU81744.1 - 1.3e-11 44.1 7.0 2.5e-11 43.2 4.9 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU81744.1 - 0.014 14.6 2.4 0.028 13.7 1.6 1.4 1 0 0 1 1 1 0 Life-span regulatory factor zf-Mss51 PF13824.1 EAU81744.1 - 0.19 11.6 2.0 0.46 10.3 1.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.2 EAU81746.2 - 2e-07 30.5 0.0 7.1e-06 25.6 0.0 3.0 2 1 1 3 3 3 1 F-box-like F-box PF00646.28 EAU81746.2 - 0.036 13.7 2.0 1.2 8.8 1.4 3.1 1 1 0 1 1 1 0 F-box domain Ubiq_cyt_C_chap PF03981.7 EAU81748.1 - 3.2e-25 88.6 0.0 6.4e-13 48.7 0.0 3.2 3 0 0 3 3 3 3 Ubiquinol-cytochrome C chaperone SR-25 PF10500.4 EAU81748.1 - 0.005 16.3 5.9 0.0081 15.6 4.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 EAU81748.1 - 1.4 9.0 7.3 0.61 10.1 1.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SSP160 PF06933.6 EAU81748.1 - 5.7 4.7 8.3 8.7 4.1 5.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Aminotran_1_2 PF00155.16 EAU81749.2 - 5.8e-18 64.9 0.0 2.8e-09 36.3 0.0 3.4 4 0 0 4 4 4 2 Aminotransferase class I and II Sporozoite_P67 PF05642.6 EAU81749.2 - 0.0079 14.1 0.7 0.011 13.6 0.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen ANF_receptor PF01094.23 EAU81750.1 - 0.11 11.3 0.2 0.55 8.9 0.0 2.0 2 0 0 2 2 2 0 Receptor family ligand binding region zf-like PF04071.7 EAU81753.2 - 0.12 12.0 4.1 1.4 8.7 0.3 3.1 2 0 0 2 2 2 0 Cysteine-rich small domain SNF2_N PF00176.18 EAU81754.1 - 2.1e-05 23.4 0.0 3.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HMG14_17 PF01101.13 EAU81756.1 - 0.22 12.2 6.0 0.82 10.3 4.2 2.0 1 0 0 1 1 1 0 HMG14 and HMG17 DPBB_1 PF03330.13 EAU81758.2 - 0.037 14.0 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Ribosomal_S15 PF00312.17 EAU81760.2 - 0.14 11.9 0.5 0.65 9.7 0.5 2.0 2 0 0 2 2 2 0 Ribosomal protein S15 APG6 PF04111.7 EAU81760.2 - 1.6 7.7 6.7 2.9 6.8 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EAU81760.2 - 4.4 6.8 9.4 1.6 8.2 3.9 1.9 2 0 0 2 2 2 0 IncA protein Mnd1 PF03962.10 EAU81760.2 - 4.6 6.8 10.4 0.18 11.4 2.3 2.0 2 0 0 2 2 2 0 Mnd1 family BAR PF03114.13 EAU81763.2 - 0.14 11.6 0.5 1.8 8.0 0.4 2.0 1 1 0 1 1 1 0 BAR domain Tet_JBP PF12851.2 EAU81764.2 - 1.6e-12 47.0 0.0 2.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF4414 PF14377.1 EAU81767.2 - 0.02 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Tropomyosin_1 PF12718.2 EAU81768.1 - 3e-05 23.9 0.6 3e-05 23.9 0.4 3.3 2 1 0 3 3 3 1 Tropomyosin like Daxx PF03344.10 EAU81768.1 - 0.0051 15.3 15.1 0.0078 14.7 10.5 1.2 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 EAU81768.1 - 0.019 13.0 6.0 0.029 12.4 4.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1664 PF07889.7 EAU81768.1 - 0.13 12.1 0.2 0.29 10.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ycf1 PF05758.7 EAU81768.1 - 0.92 7.1 3.2 1.3 6.6 2.2 1.2 1 0 0 1 1 1 0 Ycf1 GTF2I PF02946.9 EAU81769.1 - 0.0054 16.5 0.0 0.037 13.8 0.0 2.2 1 1 0 1 1 1 1 GTF2I-like repeat HMG_box_2 PF09011.5 EAU81769.1 - 0.025 14.9 0.6 0.066 13.5 0.4 1.7 1 0 0 1 1 1 0 HMG-box domain HMG_box PF00505.14 EAU81769.1 - 0.054 13.7 0.9 2.7 8.3 0.0 3.4 4 0 0 4 4 4 0 HMG (high mobility group) box DUF3249 PF11615.3 EAU81769.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3249) Sigma70_ner PF04546.8 EAU81769.1 - 0.094 12.3 7.8 0.2 11.2 5.4 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 EAU81769.1 - 0.11 10.4 10.8 0.16 9.9 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EAU81769.1 - 0.39 8.5 15.1 0.56 8.0 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EAU81769.1 - 0.41 8.7 5.6 0.56 8.2 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 YL1 PF05764.8 EAU81769.1 - 0.91 9.0 13.8 2.1 7.8 9.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.1 EAU81769.1 - 6.5 7.1 14.5 19 5.6 10.0 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tet_JBP PF12851.2 EAU81773.2 - 0.00043 19.6 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily p450 PF00067.17 EAU81779.2 - 1.2e-07 30.6 0.0 1.4e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU81781.2 - 3.3e-62 210.5 0.0 5.5e-62 209.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU81782.2 - 1.3e-61 208.5 0.0 1.8e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU81783.2 - 6e-65 219.5 0.0 7.9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU81789.2 - 4.4e-62 210.1 0.0 5.3e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lipase_3 PF01764.20 EAU81790.2 - 3.3e-06 26.7 0.1 7.7e-06 25.5 0.1 1.5 1 1 0 1 1 1 1 Lipase (class 3) ORC3_N PF07034.6 EAU81791.1 - 0.13 11.2 1.5 0.17 10.8 1.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Vfa1 PF08432.5 EAU81791.1 - 0.35 10.8 14.2 0.55 10.2 9.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 EAU81791.1 - 0.89 9.0 13.6 1.3 8.4 9.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Fucose_iso_N2 PF07882.7 EAU81791.1 - 1.7 8.3 6.6 3.1 7.4 4.6 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF2413 PF10310.4 EAU81791.1 - 4.4 6.0 13.0 5.8 5.6 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ribosomal_60s PF00428.14 EAU81792.1 - 0.014 15.8 16.5 0.021 15.2 0.2 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ribosomal_L31 PF01197.13 EAU81794.2 - 0.12 12.3 0.2 0.42 10.6 0.1 1.9 1 1 0 1 1 1 0 Ribosomal protein L31 DUF936 PF06075.7 EAU81795.1 - 3 6.6 39.3 3.8 6.3 27.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Ribosomal_S7 PF00177.16 EAU81796.1 - 8e-29 100.1 0.2 1e-28 99.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SUV3_C PF12513.3 EAU81797.1 - 5.4e-14 51.3 0.5 1.2e-13 50.2 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EAU81797.1 - 8e-10 38.4 0.0 1.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LrgB PF04172.11 EAU81798.1 - 0.00015 20.9 0.8 0.00018 20.7 0.5 1.1 1 0 0 1 1 1 1 LrgB-like family Mito_carr PF00153.22 EAU81800.1 - 3e-29 100.5 4.0 2.2e-15 56.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF605 PF04652.11 EAU81802.2 - 2.3 7.5 12.4 3.1 7.1 8.6 1.2 1 0 0 1 1 1 0 Vta1 like RAP1 PF07218.6 EAU81802.2 - 7.5 4.5 11.5 9.3 4.1 7.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-box-like PF12937.2 EAU81803.1 - 0.00025 20.7 1.6 0.00025 20.7 1.1 2.5 2 1 0 2 2 2 1 F-box-like LRR_2 PF07723.8 EAU81803.1 - 0.12 12.8 1.2 30 5.3 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat p450 PF00067.17 EAU81805.2 - 1.3e-72 244.8 0.0 1.5e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU81806.2 - 5.9e-73 245.9 0.0 7.4e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 eIF2A PF08662.6 EAU81809.2 - 5.8e-80 267.5 0.0 1.5e-79 266.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EAU81809.2 - 0.0068 16.2 0.1 1.4 8.9 0.1 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EAU81809.2 - 0.08 12.2 3.0 9.1 5.7 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DUF3796 PF12676.2 EAU81811.1 - 0.54 10.4 12.5 0.028 14.6 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Tropomyosin PF00261.15 EAU81813.1 - 0.0025 16.9 3.0 0.0039 16.3 2.1 1.2 1 0 0 1 1 1 1 Tropomyosin DUF241 PF03087.9 EAU81813.1 - 0.034 13.6 0.3 0.048 13.1 0.2 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Matrilin_ccoil PF10393.4 EAU81813.1 - 0.078 12.3 2.7 0.2 11.0 0.9 2.2 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Laminin_II PF06009.7 EAU81813.1 - 0.1 12.3 3.6 0.15 11.8 1.5 1.8 2 0 0 2 2 2 0 Laminin Domain II SKIP_SNW PF02731.10 EAU81813.1 - 0.14 11.6 3.7 0.34 10.3 2.6 1.7 1 0 0 1 1 1 0 SKIP/SNW domain DUF3552 PF12072.3 EAU81813.1 - 0.47 9.6 7.1 1.5 7.9 5.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) PAT1 PF09770.4 EAU81813.1 - 1.4 7.0 14.4 2.4 6.3 10.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MethyltransfD12 PF02086.10 EAU81814.1 - 0.015 14.7 1.6 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase S_tail_recep_bd PF14928.1 EAU81814.1 - 0.09 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain DUF1932 PF09130.6 EAU81819.1 - 0.0048 16.6 0.1 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) HisKA_3 PF07730.8 EAU81819.1 - 0.06 13.7 0.3 6.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Histidine kinase FliD_N PF02465.13 EAU81820.1 - 0.022 15.0 0.6 6.7 7.1 0.0 2.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus FlgN PF05130.7 EAU81820.1 - 0.025 14.8 0.2 0.053 13.7 0.1 1.5 1 1 0 1 1 1 0 FlgN protein zf-HIT PF04438.11 EAU81821.2 - 2.2 8.0 7.9 0.67 9.6 1.0 2.3 2 0 0 2 2 2 0 HIT zinc finger ATG16 PF08614.6 EAU81824.2 - 4.8 6.9 8.0 0.31 10.8 1.6 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Mpp10 PF04006.7 EAU81826.2 - 0.061 11.6 9.0 0.12 10.7 6.2 1.4 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 EAU81826.2 - 0.59 7.9 8.4 1.1 7.0 5.8 1.4 1 0 0 1 1 1 0 Nop14-like family eIF3_subunit PF08597.5 EAU81826.2 - 3.3 7.1 11.9 0.3 10.6 4.8 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF4637 PF15470.1 EAU81826.2 - 9.8 5.7 12.6 7.7 6.0 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) p450 PF00067.17 EAU81832.2 - 1.5e-37 129.2 0.0 1.7e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 EAU81835.2 - 1.4e-12 47.4 0.0 3.2e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU81835.2 - 3.2e-09 36.8 0.0 5.8e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAU81835.2 - 0.00058 20.0 0.0 0.0014 18.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAU81835.2 - 0.0013 18.5 0.0 0.0039 17.0 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EAU81835.2 - 0.0045 17.1 0.0 0.038 14.1 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ycf9 PF01737.12 EAU81835.2 - 0.19 11.2 0.9 0.41 10.1 0.1 1.9 2 0 0 2 2 2 0 YCF9 Kri1 PF05178.7 EAU81837.1 - 0.077 13.2 2.8 0.24 11.7 1.9 1.8 1 1 0 1 1 1 0 KRI1-like family Myb_DNA-bind_2 PF08914.6 EAU81838.2 - 1.6e-12 47.0 4.4 4.8e-12 45.4 3.1 1.9 1 1 0 1 1 1 1 Rap1 Myb domain COesterase PF00135.23 EAU81840.2 - 4.2e-84 283.1 1.7 1.6e-81 274.6 0.1 2.8 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU81840.2 - 4.5e-05 23.1 0.5 0.00068 19.2 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU81840.2 - 0.0034 16.6 0.7 0.0062 15.7 0.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EAU81841.2 - 7.3e-96 321.9 0.0 9.7e-96 321.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU81841.2 - 5.3e-08 32.7 0.0 1.4e-06 28.0 0.1 3.0 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU81841.2 - 0.025 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pyr_redox_3 PF13738.1 EAU81842.2 - 4e-25 89.0 0.0 6.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAU81842.2 - 1.2e-15 56.7 0.0 3.4e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EAU81842.2 - 7.3e-12 45.5 0.0 9.2e-10 38.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAU81842.2 - 6.8e-10 38.3 0.0 3e-08 32.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAU81842.2 - 1.9e-09 37.3 0.0 4.9e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAU81842.2 - 0.00063 19.5 0.0 0.0017 18.1 0.0 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EAU81842.2 - 0.0024 16.8 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAU81842.2 - 0.017 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain OCD_Mu_crystall PF02423.10 EAU81842.2 - 0.18 10.5 0.1 0.75 8.5 0.0 1.8 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Thi4 PF01946.12 EAU81842.2 - 0.19 10.8 0.0 0.36 9.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 EAU81843.2 - 9.2e-61 205.7 0.0 1.7e-60 204.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU81844.2 - 2.2e-65 220.9 0.0 2.9e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Per1 PF04080.8 EAU81846.1 - 9.8e-96 320.2 2.2 1.3e-95 319.8 1.5 1.2 1 0 0 1 1 1 1 Per1-like Ribonuc_L-PSP PF01042.16 EAU81847.1 - 8.1e-23 80.4 0.0 9.8e-23 80.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PC-Esterase PF13839.1 EAU81848.2 - 4.7e-08 33.1 0.6 2.2e-07 30.9 0.4 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p MgtE PF01769.11 EAU81850.1 - 4.2e-22 78.8 23.6 6.2e-09 36.2 2.5 3.7 4 0 0 4 4 4 3 Divalent cation transporter DUF2919 PF11143.3 EAU81850.1 - 0.022 14.5 1.0 0.022 14.5 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) DUF1129 PF06570.6 EAU81850.1 - 0.36 10.1 6.9 0.034 13.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ada3 PF10198.4 EAU81851.2 - 7.5e-25 87.1 3.0 7.5e-25 87.1 2.1 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 CR6_interact PF10147.4 EAU81851.2 - 0.93 8.7 10.4 0.084 12.1 1.5 2.5 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RNA_polI_A34 PF08208.6 EAU81852.1 - 1.5e-13 50.8 16.9 2.5e-13 50.1 11.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Mak10 PF04112.8 EAU81853.1 - 9.6e-20 70.4 0.0 1.8e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Polysacc_lyase PF14099.1 EAU81856.1 - 0.0012 18.5 0.1 0.0022 17.7 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide lyase Polysacc_lyase PF14099.1 EAU81857.1 - 0.079 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase Methyltransf_23 PF13489.1 EAU81858.2 - 1.6e-17 63.6 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU81858.2 - 8.9e-14 51.3 0.0 1.5e-13 50.5 0.0 1.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU81858.2 - 5.5e-12 46.0 0.0 9.9e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU81858.2 - 9.7e-11 42.0 0.0 2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU81858.2 - 1.6e-09 38.0 0.0 3.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU81858.2 - 1.7e-09 38.2 0.0 5e-09 36.7 0.0 1.8 3 0 0 3 3 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU81858.2 - 6.9e-06 25.3 0.0 8.3e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EAU81858.2 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAU81858.2 - 3.6e-05 23.8 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EAU81858.2 - 4.7e-05 22.8 0.0 6.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EAU81858.2 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 EAU81858.2 - 0.0053 15.9 0.0 0.0074 15.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EAU81858.2 - 0.008 15.1 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 EAU81858.2 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EAU81858.2 - 0.015 14.9 0.0 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EAU81858.2 - 0.034 13.0 0.0 0.09 11.6 0.0 1.7 1 1 0 1 1 1 0 DREV methyltransferase DUF43 PF01861.11 EAU81858.2 - 0.084 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Metal_resist PF13801.1 EAU81858.2 - 0.12 12.3 0.3 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 Heavy-metal resistance IMS PF00817.15 EAU81859.1 - 1.1e-41 142.1 0.9 1.7e-41 141.5 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EAU81859.1 - 3.3e-16 59.3 0.0 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EAU81859.1 - 2.2e-06 27.3 0.3 1.2e-05 25.1 0.0 2.4 3 0 0 3 3 3 1 IMS family HHH motif DUF4414 PF14377.1 EAU81859.1 - 2.8e-06 27.2 2.1 0.051 13.5 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) PTCB-BRCT PF12738.2 EAU81859.1 - 7.7e-05 22.4 0.0 0.00036 20.3 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EAU81859.1 - 0.00016 21.7 0.1 0.00074 19.6 0.0 2.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain DUF1805 PF08827.6 EAU81859.1 - 0.031 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Band_7 PF01145.20 EAU81859.1 - 0.048 13.5 0.0 0.33 10.8 0.0 2.4 3 0 0 3 3 3 0 SPFH domain / Band 7 family MHC_II_alpha PF00993.15 EAU81859.1 - 0.15 11.6 0.0 0.45 10.1 0.0 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain DUF1455 PF07306.6 EAU81860.2 - 0.12 12.4 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) p450 PF00067.17 EAU81862.2 - 2.1e-58 197.9 0.0 3e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.16 EAU81863.2 - 1.5e-28 98.8 0.0 2.6e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pribosyltran_N PF13793.1 EAU81864.1 - 8.8e-52 173.7 0.3 5.1e-50 168.0 0.0 2.9 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EAU81864.1 - 3.6e-35 121.3 1.3 5.3e-32 111.0 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EAU81864.1 - 1.2e-14 54.0 0.3 3.1e-13 49.5 0.2 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EAU81864.1 - 7.7e-06 25.2 0.1 1.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EAU81864.1 - 0.00058 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase AA_kinase PF00696.23 EAU81865.1 - 1.9e-40 138.9 0.8 2.9e-40 138.3 0.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EAU81865.1 - 1.8e-09 37.1 1.0 3.1e-05 23.6 0.2 2.7 2 0 0 2 2 2 2 PUA domain Apidaecin PF00807.12 EAU81865.1 - 0.089 12.4 1.0 0.17 11.5 0.7 1.4 1 0 0 1 1 1 0 Apidaecin Hydrophobin PF01185.13 EAU81871.2 - 5.9e-20 71.5 11.6 7e-20 71.2 8.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_9 PF02819.10 EAU81871.2 - 1.5 8.9 7.3 0.74 9.9 0.7 2.3 2 0 0 2 2 2 0 Spider toxin FAD_binding_2 PF00890.19 EAU81873.1 - 6.6e-125 417.2 4.0 8.2e-125 416.9 2.8 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EAU81873.1 - 5.9e-48 161.9 0.2 8.8e-48 161.4 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EAU81873.1 - 2.3e-08 34.1 0.0 0.00028 20.8 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU81873.1 - 4.2e-07 29.2 0.5 0.0012 17.9 0.0 2.8 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EAU81873.1 - 8.8e-06 24.8 1.7 0.006 15.4 1.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EAU81873.1 - 3.8e-05 22.7 0.1 0.00095 18.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU81873.1 - 0.003 16.6 0.2 0.0055 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EAU81873.1 - 0.093 11.1 2.7 0.25 9.7 0.6 2.5 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.1 EAU81873.1 - 0.099 12.6 0.2 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hydrophobin PF01185.13 EAU81875.2 - 1.6e-18 66.9 8.9 4.4e-18 65.5 6.2 1.6 1 1 0 1 1 1 1 Fungal hydrophobin DUF4418 PF14387.1 EAU81875.2 - 0.17 11.6 3.6 2.4 7.9 2.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4418) CBM_19 PF03427.8 EAU81875.2 - 3.6 7.4 8.6 0.32 10.7 0.2 2.6 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) Mito_carr PF00153.22 EAU81876.2 - 2.7e-60 200.1 0.0 2.2e-21 75.3 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein V_ATPase_I PF01496.14 EAU81878.1 - 7.2e-275 913.6 0.0 8.2e-275 913.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.7 EAU81878.1 - 0.0018 18.6 2.8 0.0026 18.0 0.5 2.3 3 0 0 3 3 3 1 SlyX Clusterin PF01093.12 EAU81878.1 - 0.09 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Clusterin Sec5 PF15469.1 EAU81878.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 SPC12 PF06645.8 EAU81878.1 - 0.6 9.9 6.4 10 5.9 0.1 3.5 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ABC_tran PF00005.22 EAU81879.1 - 1.1e-44 152.0 0.1 5.2e-22 78.6 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAU81879.1 - 2.4e-14 54.0 7.2 1.7e-05 24.9 0.8 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EAU81879.1 - 1e-13 51.0 0.9 0.00087 18.5 0.0 4.4 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAU81879.1 - 4.3e-09 35.7 0.2 0.0028 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EAU81879.1 - 1.3e-07 32.4 0.5 0.0015 19.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAU81879.1 - 7.3e-07 29.3 0.0 0.007 16.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 EAU81879.1 - 4e-06 26.8 0.3 0.0036 17.1 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 Miro PF08477.8 EAU81879.1 - 4.5e-06 27.1 0.0 0.1 13.0 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 EAU81879.1 - 5.9e-06 26.1 0.0 0.027 14.3 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EAU81879.1 - 6.8e-06 25.3 0.4 1.1 8.2 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain AAA_23 PF13476.1 EAU81879.1 - 1.2e-05 25.7 7.2 0.039 14.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAU81879.1 - 1.3e-05 24.4 0.0 0.022 13.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EAU81879.1 - 1.4e-05 24.9 0.0 0.31 11.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EAU81879.1 - 3e-05 24.3 0.2 0.027 14.7 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAU81879.1 - 3.7e-05 23.3 0.2 0.064 12.6 0.1 2.9 3 0 0 3 3 2 2 AAA-like domain AAA_28 PF13521.1 EAU81879.1 - 4.8e-05 23.3 0.0 0.17 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EAU81879.1 - 6.5e-05 23.1 0.0 1.6 8.9 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAU81879.1 - 0.00012 21.5 0.1 0.45 9.8 0.0 3.8 4 0 0 4 4 3 1 AAA domain ArgK PF03308.11 EAU81879.1 - 0.00015 20.6 2.4 0.34 9.6 0.0 3.3 3 0 0 3 3 3 2 ArgK protein MobB PF03205.9 EAU81879.1 - 0.00017 21.2 0.1 0.82 9.3 0.0 3.3 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EAU81879.1 - 0.00018 21.6 0.0 0.65 10.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EAU81879.1 - 0.00033 20.3 0.7 0.54 9.9 0.0 2.9 2 1 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EAU81879.1 - 0.00033 20.5 0.0 0.94 9.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.1 EAU81879.1 - 0.00049 18.6 0.1 1.2 7.4 0.0 3.1 3 1 0 3 3 3 2 AAA domain HEAT_2 PF13646.1 EAU81879.1 - 0.00051 20.2 15.3 0.015 15.5 0.2 5.6 4 1 2 6 6 5 1 HEAT repeats Arch_ATPase PF01637.13 EAU81879.1 - 0.0037 17.0 2.9 5.3 6.6 0.6 3.8 3 1 0 3 3 3 0 Archaeal ATPase DUF815 PF05673.8 EAU81879.1 - 0.0046 15.9 0.3 2.2 7.1 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EAU81879.1 - 0.0054 16.2 0.3 1.7 8.0 0.0 3.3 3 1 0 3 3 3 1 FtsK/SpoIIIE family KAP_NTPase PF07693.9 EAU81879.1 - 0.0065 15.5 0.1 0.038 12.9 0.1 2.2 2 0 0 2 2 2 1 KAP family P-loop domain Chromo PF00385.19 EAU81879.1 - 0.0073 15.9 0.2 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_14 PF13173.1 EAU81879.1 - 0.016 15.0 0.8 5.6 6.8 0.8 3.6 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EAU81879.1 - 0.017 14.9 0.1 0.59 9.9 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.1 EAU81879.1 - 0.034 14.1 12.0 0.051 13.5 0.5 4.5 4 1 0 4 4 4 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 EAU81879.1 - 0.036 14.1 0.1 0.37 10.8 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF3437 PF11919.3 EAU81879.1 - 0.05 13.3 0.3 0.75 9.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HEAT PF02985.17 EAU81879.1 - 0.056 13.5 2.3 56 4.2 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat ATP-synt_ab PF00006.20 EAU81879.1 - 0.095 12.1 0.0 2.7 7.4 0.0 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EAU81879.1 - 0.13 11.7 2.1 17 4.7 0.1 3.9 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain U3snoRNP10 PF12397.3 EAU81879.1 - 0.13 12.2 6.0 0.072 13.0 1.1 2.5 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 AAA_5 PF07728.9 EAU81879.1 - 0.2 11.3 5.7 5.7 6.6 0.1 4.5 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) HEAT_EZ PF13513.1 EAU81879.1 - 7.2 7.2 14.2 26 5.4 0.1 5.6 5 2 2 7 7 5 0 HEAT-like repeat F-box-like PF12937.2 EAU81881.1 - 2.7e-06 26.9 1.1 1.1e-05 25.1 0.7 2.1 1 0 0 1 1 1 1 F-box-like AA_permease_2 PF13520.1 EAU81882.1 - 0.018 13.5 1.3 0.03 12.8 0.9 1.2 1 1 0 1 1 1 0 Amino acid permease PEP-utilizers PF00391.18 EAU81882.1 - 0.019 14.5 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain DUF202 PF02656.10 EAU81882.1 - 0.12 12.6 3.0 0.14 12.4 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF202) 7TMR-DISM_7TM PF07695.6 EAU81884.2 - 0.0054 16.4 0.5 0.007 16.0 0.3 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF998 PF06197.8 EAU81884.2 - 0.029 13.6 1.5 0.039 13.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2721 PF11026.3 EAU81884.2 - 3 7.4 5.3 5.1 6.7 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Ras PF00071.17 EAU81885.1 - 1.2e-62 210.0 0.2 1.4e-62 209.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU81885.1 - 1.6e-20 73.7 0.0 2.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU81885.1 - 5.5e-12 45.2 0.0 7.1e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAU81885.1 - 1.2e-07 31.6 0.1 1.9e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU81885.1 - 2.5e-05 23.7 0.1 7.3e-05 22.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EAU81885.1 - 4.1e-05 23.7 0.0 0.00017 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EAU81885.1 - 0.0019 17.3 0.1 0.0021 17.1 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EAU81885.1 - 0.002 17.3 0.0 0.0069 15.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EAU81885.1 - 0.0029 16.7 0.1 0.0045 16.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAU81885.1 - 0.0085 15.3 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EAU81885.1 - 0.017 14.5 0.0 0.055 12.9 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EAU81885.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EAU81885.1 - 0.024 13.8 0.2 0.1 11.9 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 EAU81885.1 - 0.026 14.8 0.1 0.044 14.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EAU81885.1 - 0.042 13.8 0.1 0.077 12.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EAU81885.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain YvfG PF09628.5 EAU81885.1 - 0.13 12.4 0.1 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 YvfG protein AAA_5 PF07728.9 EAU81885.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) F-box-like PF12937.2 EAU81886.1 - 0.0011 18.6 0.0 0.0031 17.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like Peptidase_M50B PF13398.1 EAU81887.2 - 3.5e-47 160.3 17.5 5.3e-47 159.8 12.1 1.2 1 0 0 1 1 1 1 Peptidase M50B-like DUF202 PF02656.10 EAU81887.2 - 4.5 7.5 10.4 1.5e+02 2.6 4.6 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) p450 PF00067.17 EAU81889.2 - 1.5e-62 211.6 0.0 2.6e-62 210.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 TMEM173 PF15009.1 EAU81895.2 - 0.15 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 173 Hydrophobin PF01185.13 EAU81903.1 - 5.2e-18 65.2 8.2 6.6e-18 64.9 5.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AMP-binding PF00501.23 EAU81904.1 - 1.4e-80 270.7 0.0 1.9e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_C48 PF02902.14 EAU81905.2 - 2.4e-12 46.9 0.0 4.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Sec39 PF08314.6 EAU81905.2 - 0.057 11.3 0.0 0.088 10.7 0.0 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 PLRV_ORF5 PF01690.12 EAU81906.2 - 0.11 11.5 5.7 0.13 11.3 3.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF3618 PF12277.3 EAU81906.2 - 0.13 12.3 0.5 0.13 12.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Neur_chan_memb PF02932.11 EAU81906.2 - 0.34 10.7 3.9 0.39 10.5 2.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.14 EAU81906.2 - 1 8.0 7.6 1.3 7.6 5.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vir_act_alpha_C PF10400.4 EAU81906.2 - 1.7 9.0 10.8 1.9 8.9 0.0 3.4 3 1 1 4 4 4 0 Virulence activator alpha C-term Acyl-CoA_ox_N PF14749.1 EAU81906.2 - 9.1 6.5 10.5 24 5.2 7.3 1.8 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Cauli_VI PF01693.11 EAU81908.1 - 9.3e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Nop14 PF04147.7 EAU81909.2 - 0.26 9.1 17.5 0.31 8.9 12.1 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_LMP1 PF05297.6 EAU81909.2 - 0.26 10.1 8.0 0.32 9.8 5.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TFIIA PF03153.8 EAU81909.2 - 0.4 10.5 20.1 0.53 10.1 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 EAU81909.2 - 1.5 8.3 15.2 2.1 7.7 10.6 1.1 1 0 0 1 1 1 0 PPP4R2 Daxx PF03344.10 EAU81909.2 - 2 6.7 13.4 2.5 6.4 9.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EAU81909.2 - 2.5 7.4 8.3 3.7 6.8 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cwf_Cwc_15 PF04889.7 EAU81909.2 - 3.1 7.4 16.5 4.8 6.8 11.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2076 PF09849.4 EAU81909.2 - 4.8 7.1 20.8 7.2 6.5 14.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CDC45 PF02724.9 EAU81909.2 - 6.8 4.5 17.5 9 4.1 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EAU81909.2 - 8.1 5.6 17.1 9.9 5.3 11.9 1.1 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 EAU81909.2 - 9.1 4.5 17.7 13 4.0 12.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) p450 PF00067.17 EAU81911.1 - 0.0018 16.8 0.0 0.018 13.5 0.1 2.3 2 1 0 2 2 2 1 Cytochrome P450 DNA_pol_B_exo2 PF10108.4 EAU81912.2 - 0.046 13.2 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RhoGEF PF00621.15 EAU81913.2 - 4.6e-40 137.3 6.7 8.6e-40 136.5 4.7 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.1 EAU81913.2 - 2.2e-21 75.1 4.9 1.1e-10 40.8 0.2 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.23 EAU81913.2 - 1.8e-20 72.0 1.3 1.7e-11 43.3 0.1 2.7 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 EAU81913.2 - 6.7e-15 54.7 0.0 1.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 EAU81913.2 - 4.3e-13 48.5 0.0 2.4e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PH PF00169.24 EAU81913.2 - 1.4e-06 28.4 0.0 3.2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.1 EAU81913.2 - 4e-05 23.6 0.0 0.00018 21.5 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain pair WH2 PF02205.15 EAU81913.2 - 8.2e-05 22.0 0.0 0.00026 20.4 0.0 2.0 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.27 EAU81913.2 - 0.00052 19.1 0.2 0.47 9.8 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EAU81913.2 - 0.12 12.3 0.2 18 5.5 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain F-box-like PF12937.2 EAU81915.2 - 3e-06 26.8 3.8 9.4e-06 25.2 2.6 1.9 1 0 0 1 1 1 1 F-box-like CHAT PF12770.2 EAU81916.2 - 5.5e-30 104.4 0.0 1e-29 103.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU81916.2 - 1.2e-18 66.7 0.0 0.024 14.5 0.0 7.5 2 1 5 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EAU81916.2 - 2.9e-10 39.6 0.0 0.047 13.3 0.0 7.1 3 2 4 7 7 7 3 TPR repeat TPR_10 PF13374.1 EAU81916.2 - 6.6e-05 22.7 13.7 1.7 8.6 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat F-box PF00646.28 EAU81917.2 - 2e-06 27.2 0.1 3.1e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU81917.2 - 0.0014 18.3 0.4 0.0022 17.6 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU81918.2 - 0.036 13.7 0.9 0.1 12.3 0.6 1.8 1 0 0 1 1 1 0 F-box-like CBM_21 PF03370.8 EAU81920.2 - 2.8e-30 104.6 0.1 4.5e-30 103.9 0.1 1.3 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit ADK PF00406.17 EAU81921.1 - 1.4e-58 197.0 0.0 1.7e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EAU81921.1 - 1.2e-15 56.8 0.0 3.5e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EAU81921.1 - 0.0015 19.3 0.0 0.0024 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU81921.1 - 0.0016 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU81921.1 - 0.023 15.0 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAU81921.1 - 0.033 13.2 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin p450 PF00067.17 EAU81922.1 - 1.1e-69 235.2 0.0 1.4e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU81926.2 - 1.1e-39 136.3 0.1 2e-16 59.5 0.0 3.7 3 1 1 4 4 4 3 Cytochrome P450 p450 PF00067.17 EAU81927.1 - 5.3e-68 229.6 0.0 7.1e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4083 PF13314.1 EAU81927.1 - 0.12 12.2 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) p450 PF00067.17 EAU81929.2 - 6.6e-69 232.6 0.0 1.3e-68 231.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ORC4_C PF14629.1 EAU81930.2 - 0.0055 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus Antimicrobial_2 PF08023.7 EAU81932.1 - 0.021 15.1 4.3 0.098 12.9 0.7 2.3 2 0 0 2 2 2 0 Frog antimicrobial peptide THUMP PF02926.12 EAU81933.1 - 2.5e-14 53.3 0.8 3.5e-14 52.9 0.6 1.2 1 0 0 1 1 1 1 THUMP domain SCO1-SenC PF02630.9 EAU81933.1 - 0.022 14.3 0.5 0.054 13.1 0.3 1.7 1 1 0 1 1 1 0 SCO1/SenC KSHV_K8 PF07188.6 EAU81933.1 - 0.055 12.6 0.1 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein F-box-like PF12937.2 EAU81934.1 - 0.0066 16.1 0.2 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like IPK PF03770.11 EAU81936.1 - 1.1e-44 152.5 0.0 1.4e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_60s PF00428.14 EAU81936.1 - 0.001 19.3 8.7 0.0025 18.1 6.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 EAU81936.1 - 0.11 12.6 9.0 0.25 11.6 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EAU81936.1 - 0.22 11.0 8.0 0.43 10.0 5.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EAU81936.1 - 0.74 9.0 6.1 1 8.5 4.2 1.1 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 EAU81936.1 - 0.83 7.7 7.1 1.2 7.2 4.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein AF1Q PF15017.1 EAU81936.1 - 2 8.3 7.5 5 7.1 5.2 1.6 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Nop14 PF04147.7 EAU81936.1 - 2.3 6.0 11.6 3.3 5.5 8.1 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.3 EAU81936.1 - 5.2 6.9 12.1 11 5.8 8.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.8 EAU81936.1 - 9.2 5.8 13.4 1.6 8.3 6.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Methyltransf_31 PF13847.1 EAU81938.1 - 9.4e-20 70.7 0.0 1.3e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU81938.1 - 4.5e-17 62.3 0.0 8.2e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.5 EAU81938.1 - 4.7e-15 55.2 0.0 7.8e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.15 EAU81938.1 - 4e-14 52.3 0.0 5.9e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EAU81938.1 - 3.4e-13 49.6 0.0 5.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU81938.1 - 3.7e-12 46.7 0.0 1.3e-11 45.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU81938.1 - 6.1e-12 45.6 0.1 1.9e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU81938.1 - 2.5e-11 43.8 0.0 4.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU81938.1 - 3.8e-11 43.3 0.0 8.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU81938.1 - 3.8e-08 32.7 0.0 7.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EAU81938.1 - 3.3e-06 26.7 0.0 5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EAU81938.1 - 7e-06 25.5 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EAU81938.1 - 7.2e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.12 EAU81938.1 - 0.00013 21.1 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.7 EAU81938.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EAU81938.1 - 0.0014 19.4 0.0 0.0048 17.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EAU81938.1 - 0.0026 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 EAU81938.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Met_10 PF02475.11 EAU81938.1 - 0.021 14.4 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.12 EAU81938.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase NMT1 PF09084.6 EAU81938.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 NMT1/THI5 like RrnaAD PF00398.15 EAU81938.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Helicase_C PF00271.26 EAU81942.1 - 1.7e-07 30.9 0.1 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fer2_BFD PF04324.10 EAU81942.1 - 0.16 12.0 0.5 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain LRR_4 PF12799.2 EAU81944.2 - 0.094 12.3 3.0 2.2 8.0 0.2 3.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Herpes_LMP2 PF07415.6 EAU81944.2 - 0.11 11.0 0.1 0.11 11.0 0.0 1.7 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein adh_short PF00106.20 EAU81947.1 - 6.9e-25 87.8 0.1 1.7e-24 86.6 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU81947.1 - 8e-18 65.0 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU81947.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EAU81947.1 - 0.0026 16.7 0.1 0.0037 16.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EAU81947.1 - 0.0069 16.0 0.2 0.011 15.4 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EAU81947.1 - 0.017 15.3 0.2 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EAU81947.1 - 0.025 14.6 0.0 0.053 13.5 0.0 1.6 2 0 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 EAU81947.1 - 0.03 14.4 0.2 0.055 13.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EAU81947.1 - 0.036 13.1 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F-box-like PF12937.2 EAU81948.2 - 0.013 15.2 0.2 0.023 14.4 0.2 1.4 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EAU81954.1 - 0.00061 19.3 0.1 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU81954.1 - 0.073 12.8 0.1 0.098 12.3 0.1 1.2 1 0 0 1 1 1 0 F-box-like CDC45 PF02724.9 EAU81954.1 - 0.11 10.5 2.0 0.11 10.4 1.4 1.0 1 0 0 1 1 1 0 CDC45-like protein LZ_Tnp_IS66 PF13007.2 EAU81954.1 - 7.3 7.3 10.4 7.5 7.2 1.5 2.1 1 1 1 2 2 2 0 Transposase C of IS166 homeodomain Pkinase PF00069.20 EAU81955.1 - 3.2e-45 154.2 0.0 1.6e-43 148.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU81955.1 - 2.5e-19 69.3 0.0 2.3e-18 66.2 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EAU81955.1 - 0.0012 17.9 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU81955.1 - 0.017 14.1 0.0 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinase-like MIP-T3 PF10243.4 EAU81958.1 - 7.5 4.9 7.2 6.7 5.0 5.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Glyco_hydro_3 PF00933.16 EAU81960.2 - 6.2e-67 225.6 0.0 3.4e-52 177.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAU81960.2 - 1.8e-49 168.3 0.0 2.5e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAU81960.2 - 2.5e-18 65.7 0.0 4.4e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PAN_4 PF14295.1 EAU81962.1 - 0.033 13.9 1.3 0.068 12.8 0.9 1.6 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.1 EAU81963.1 - 0.29 10.8 3.4 0.79 9.4 2.4 1.8 1 1 0 1 1 1 0 PAN domain DUF1691 PF07950.6 EAU81964.1 - 2.4e-10 40.3 0.1 0.00012 22.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) PsbX PF06596.6 EAU81964.1 - 3.1 7.5 6.0 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) E1-E2_ATPase PF00122.15 EAU81965.2 - 1.9e-39 135.0 5.4 1.2e-37 129.2 1.9 3.4 1 1 1 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAU81965.2 - 5.7e-26 91.1 14.1 1.5e-19 70.2 0.2 3.8 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAU81965.2 - 4.4e-24 86.1 0.0 7.6e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAU81965.2 - 2.2e-19 69.2 0.0 4.7e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAU81965.2 - 4.1e-16 58.1 0.0 1.1e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAU81965.2 - 1.6e-11 44.7 0.0 3.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAU81965.2 - 4.4e-05 23.1 1.4 0.0065 16.0 0.7 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase ABC2_membrane PF01061.19 EAU81966.2 - 2.7e-36 124.7 17.4 2.7e-36 124.7 12.0 2.6 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.22 EAU81966.2 - 6.7e-25 87.9 0.0 1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EAU81966.2 - 0.00014 21.1 0.1 0.00045 19.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EAU81966.2 - 0.00026 21.0 0.8 0.018 15.0 0.3 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAU81966.2 - 0.0059 16.0 0.1 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAU81966.2 - 0.011 15.2 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EAU81966.2 - 0.016 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU81966.2 - 0.043 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 EAU81966.2 - 0.057 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EAU81966.2 - 0.063 12.8 0.5 0.099 12.2 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAU81966.2 - 0.1 12.5 0.9 0.18 11.7 0.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU81966.2 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EAU81966.2 - 0.12 12.5 0.1 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EAU81966.2 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EAU81966.2 - 0.14 12.4 0.2 0.24 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAU81966.2 - 0.2 12.4 0.6 0.44 11.3 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU81966.2 - 0.28 11.4 0.1 0.54 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAU81966.2 - 0.49 9.1 0.2 0.78 8.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC2_membrane_3 PF12698.2 EAU81966.2 - 2.5 7.0 41.7 0.01 14.8 21.0 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein Cerato-platanin PF07249.7 EAU81968.1 - 1.4e-41 141.2 0.7 1.6e-41 141.0 0.5 1.0 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 EAU81969.2 - 9.5e-47 157.8 0.2 1.1e-46 157.6 0.1 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EAU81969.2 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Barwin family F-box PF00646.28 EAU81970.1 - 2.5e-09 36.5 0.1 6.6e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAU81970.1 - 2e-07 30.6 0.1 5.5e-07 29.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EAU81970.1 - 0.013 15.2 0.5 0.044 13.5 0.1 2.1 2 1 0 2 2 2 0 F-box-like domain Elongin_A PF06881.6 EAU81970.1 - 0.092 13.1 5.1 0.31 11.4 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Enkurin PF13864.1 EAU81970.1 - 2.4 8.4 5.7 0.51 10.5 1.3 1.8 2 0 0 2 2 2 0 Calmodulin-binding F-box PF00646.28 EAU81971.2 - 1.8e-05 24.2 0.1 6e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU81971.2 - 0.00032 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like LIM PF00412.17 EAU81971.2 - 0.076 13.0 3.5 0.86 9.7 0.0 3.4 3 0 0 3 3 3 0 LIM domain Hydrophobin PF01185.13 EAU81972.1 - 1.7e-20 73.2 13.9 2e-20 72.9 9.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin VCBS PF13517.1 EAU81973.2 - 2.7e-26 91.7 10.0 2e-07 31.2 2.0 5.0 4 2 0 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EAU81973.2 - 5.8e-09 35.3 17.6 0.079 12.6 0.0 6.9 7 0 0 7 7 7 5 FG-GAP repeat TcdB_toxin_midN PF12256.3 EAU81973.2 - 5.1e-08 32.5 3.3 0.42 10.0 0.0 6.1 4 1 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region Internalin_N PF12354.3 EAU81973.2 - 0.76 9.4 2.3 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal p450 PF00067.17 EAU81974.2 - 2.3e-67 227.4 0.1 1.4e-65 221.6 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 Med25_VWA PF11265.3 EAU81974.2 - 0.075 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A MFS_1 PF07690.11 EAU81975.2 - 7.7e-27 93.9 28.9 1.1e-26 93.4 20.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU81975.2 - 2.3e-08 33.0 5.4 2.3e-08 33.0 3.8 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EAU81975.2 - 1.8e-06 26.4 3.4 3.3e-06 25.6 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SPACA7 PF15307.1 EAU81976.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 DUF4381 PF14316.1 EAU81977.1 - 0.048 13.7 0.7 0.08 13.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) YajC PF02699.10 EAU81977.1 - 0.084 12.5 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2236 PF09995.4 EAU81978.2 - 3.6e-09 36.2 1.1 1.9e-08 33.8 0.3 2.3 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) RSN1_TM PF13967.1 EAU81978.2 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport MIF4G PF02854.14 EAU81980.2 - 6e-27 94.4 0.1 6e-27 94.4 0.1 2.5 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EAU81980.2 - 2.2e-23 82.1 0.1 4.3e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 MA3 domain Packaging_FI PF14000.1 EAU81980.2 - 0.03 14.5 8.4 0.49 10.5 0.3 2.6 2 0 0 2 2 2 0 DNA packaging protein FI DJ-1_PfpI PF01965.19 EAU81981.1 - 0.0098 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4505 PF14956.1 EAU81983.1 - 0.045 13.3 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) PP2C PF00481.16 EAU81984.2 - 2.6e-17 63.0 0.0 1.1e-13 51.1 0.0 3.3 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.7 EAU81984.2 - 0.03 14.0 0.1 11 5.6 0.0 2.8 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EAU81984.2 - 0.034 13.5 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C F-box-like PF12937.2 EAU81985.2 - 0.0066 16.1 4.1 0.01 15.5 1.1 2.7 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU81987.1 - 2e-06 27.3 0.4 1.7e-05 24.4 0.3 2.4 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU81987.1 - 0.089 12.4 0.5 1.2 8.8 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) DDOST_48kD PF03345.9 EAU81990.1 - 4.9e-98 328.4 0.0 5.6e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta XPA_C PF05181.7 EAU81990.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 XPA protein C-terminus HemY_N PF07219.8 EAU81991.1 - 0.022 14.2 0.2 0.048 13.2 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus 7tm_4 PF13853.1 EAU81991.1 - 0.037 13.8 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 Olfactory receptor DUF605 PF04652.11 EAU81991.1 - 1.6 8.0 12.0 2 7.7 8.3 1.1 1 0 0 1 1 1 0 Vta1 like Peptidase_S10 PF00450.17 EAU81994.2 - 2e-117 392.8 0.0 2.6e-117 392.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EAU81994.2 - 4e-05 23.6 0.0 0.00039 20.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF357 PF04010.8 EAU81994.2 - 0.13 11.9 0.2 5.8 6.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF357) Calcipressin PF04847.7 EAU81995.1 - 3.4e-34 118.0 0.0 3.4e-34 118.0 0.0 1.8 2 0 0 2 2 2 1 Calcipressin RRM_5 PF13893.1 EAU81995.1 - 0.0055 16.5 0.0 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU81995.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1014 PF06244.7 EAU81996.2 - 1.1e-22 80.5 17.9 1.1e-22 80.5 12.4 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) DUF2201_N PF13203.1 EAU81996.2 - 6.9 5.7 13.9 12 4.9 9.6 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain MFS_1 PF07690.11 EAU81997.2 - 3.5e-29 101.6 17.2 4.8e-29 101.1 11.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU81997.2 - 1.5e-08 33.6 5.8 5.4e-08 31.8 4.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EAU81997.2 - 1.7e-07 30.0 3.8 0.0005 18.5 0.0 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein CDC73 PF05179.9 EAU82000.1 - 1.2e-53 182.2 0.9 1.6e-53 181.8 0.6 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family SSP160 PF06933.6 EAU82000.1 - 0.00081 17.5 0.3 0.0011 17.0 0.2 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 F-box PF00646.28 EAU82002.2 - 8.3e-07 28.5 0.1 2.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU82002.2 - 0.0024 17.5 0.0 0.0065 16.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF3138 PF11336.3 EAU82002.2 - 0.059 11.5 0.1 0.087 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Hydrophobin PF01185.13 EAU82003.1 - 3.9e-21 75.3 12.5 4.8e-21 75.0 8.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Sec2p PF06428.6 EAU82004.2 - 0.00043 20.0 14.6 0.0019 18.0 10.0 2.2 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p Dor1 PF04124.7 EAU82004.2 - 0.00064 18.2 10.7 0.005 15.3 6.2 2.1 1 1 1 2 2 2 2 Dor1-like family BLOC1_2 PF10046.4 EAU82004.2 - 0.0068 16.5 1.1 0.0068 16.5 0.8 2.5 1 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EAU82004.2 - 0.008 16.3 9.6 0.03 14.4 4.1 2.4 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family Dzip-like_N PF13815.1 EAU82004.2 - 0.0098 15.6 2.9 0.0098 15.6 2.0 2.4 1 1 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal MerR-DNA-bind PF09278.6 EAU82004.2 - 0.012 16.0 14.1 0.033 14.5 1.1 3.0 2 1 2 4 4 3 0 MerR, DNA binding Prominin PF05478.6 EAU82004.2 - 0.029 11.9 8.2 0.035 11.6 5.7 1.1 1 0 0 1 1 1 0 Prominin Fmp27_WPPW PF10359.4 EAU82004.2 - 0.04 12.3 12.7 0.063 11.6 8.8 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.1 EAU82004.2 - 0.041 13.0 19.7 0.054 12.6 12.9 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EAU82004.2 - 0.058 13.6 5.9 4.4 7.6 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AstA PF04958.7 EAU82004.2 - 0.059 11.7 4.0 0.053 11.9 1.8 1.6 1 1 1 2 2 2 0 Arginine N-succinyltransferase beta subunit CENP-Q PF13094.1 EAU82004.2 - 0.07 13.1 26.5 0.062 13.3 6.4 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Myosin_tail_1 PF01576.14 EAU82004.2 - 0.087 10.5 26.0 0.2 9.3 18.0 1.5 1 1 0 1 1 1 0 Myosin tail RTBV_P46 PF06216.6 EAU82004.2 - 0.1 11.4 1.9 0.12 11.1 1.3 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein FUSC PF04632.7 EAU82004.2 - 0.12 10.7 10.1 0.14 10.5 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.10 EAU82004.2 - 0.16 11.1 12.3 0.23 10.6 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.6 EAU82004.2 - 0.17 10.5 10.1 0.2 10.2 7.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) TMF_DNA_bd PF12329.3 EAU82004.2 - 0.17 11.7 14.4 0.063 13.0 3.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EAU82004.2 - 0.23 11.8 16.7 1.1 9.6 4.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Synaptonemal_3 PF15191.1 EAU82004.2 - 0.25 11.0 3.6 0.21 11.3 0.7 2.2 3 0 0 3 3 3 0 Synaptonemal complex central element protein 3 DASH_Dam1 PF08653.5 EAU82004.2 - 0.35 10.6 1.8 22 4.8 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 IncA PF04156.9 EAU82004.2 - 0.36 10.4 20.6 0.47 10.0 11.3 2.1 1 1 1 2 2 2 0 IncA protein AAA_13 PF13166.1 EAU82004.2 - 0.45 8.9 11.4 0.54 8.6 7.9 1.0 1 0 0 1 1 1 0 AAA domain Nup54 PF13874.1 EAU82004.2 - 0.53 9.9 17.1 1.9 8.1 10.4 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF2937 PF11157.3 EAU82004.2 - 0.65 9.3 12.2 2.2 7.5 2.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) Spectrin PF00435.16 EAU82004.2 - 0.9 9.8 15.0 2 8.7 3.2 2.5 1 1 1 2 2 2 0 Spectrin repeat ADIP PF11559.3 EAU82004.2 - 1 9.2 24.4 2.2 8.1 7.0 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.2 EAU82004.2 - 1.1 9.1 23.2 0.67 9.8 9.6 2.2 1 1 1 2 2 2 0 Tropomyosin like Spc24 PF08286.6 EAU82004.2 - 1.2 8.8 16.2 2.3 7.9 4.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Spore_III_AB PF09548.5 EAU82004.2 - 1.2 8.8 9.4 0.14 11.9 1.6 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DivIC PF04977.10 EAU82004.2 - 1.5 8.3 18.4 0.75 9.3 1.2 3.4 1 1 2 3 3 3 0 Septum formation initiator TarH PF02203.10 EAU82004.2 - 1.7 8.4 11.6 2.4 7.9 8.1 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue HAUS6_N PF14661.1 EAU82004.2 - 2 7.7 20.2 3.9 6.7 5.5 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Spc7 PF08317.6 EAU82004.2 - 2.1 6.9 17.6 0.45 9.1 7.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF607 PF04678.8 EAU82004.2 - 2.4 8.0 15.1 0.1 12.5 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 FliD_C PF07195.7 EAU82004.2 - 2.5 7.3 8.0 0.74 9.0 1.7 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Mt_ATP-synt_B PF05405.9 EAU82004.2 - 3 7.2 11.1 2.5 7.5 6.6 1.7 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Adeno_PIX PF03955.9 EAU82004.2 - 3.2 8.3 10.5 3.6 8.1 2.0 2.7 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DivIVA PF05103.8 EAU82004.2 - 3.4 7.7 22.0 1.1 9.2 4.7 2.6 2 1 1 3 3 2 0 DivIVA protein WXG100 PF06013.7 EAU82004.2 - 4.1 7.4 10.5 3.6 7.6 1.6 2.9 2 1 0 3 3 2 0 Proteins of 100 residues with WXG DUF4404 PF14357.1 EAU82004.2 - 5.9 7.3 12.1 11 6.4 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) APG6 PF04111.7 EAU82004.2 - 7.2 5.5 21.0 3.3 6.6 11.3 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 Occludin_ELL PF07303.8 EAU82004.2 - 7.5 7.3 15.3 7.2 7.4 3.2 2.6 1 1 1 2 2 2 0 Occludin homology domain CorA PF01544.13 EAU82004.2 - 8.5 5.3 8.9 23 3.8 5.1 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 EAU82004.2 - 8.8 4.6 11.2 12 4.1 7.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 EAU82004.2 - 9.7 6.6 12.1 2.5 8.5 3.7 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Dehydrin PF00257.14 EAU82005.1 - 0.00011 22.5 5.3 0.012 15.9 0.0 3.6 2 2 1 3 3 3 1 Dehydrin Stimulus_sens_1 PF13756.1 EAU82005.1 - 0.0021 18.4 1.8 2.3 8.6 0.0 3.6 1 1 3 4 4 4 2 Stimulus-sensing domain JSRP PF15312.1 EAU82005.1 - 0.037 13.9 5.4 25 4.9 0.2 4.5 2 2 3 5 5 5 0 Junctional sarcoplasmic reticulum protein DUF637 PF04830.8 EAU82005.1 - 0.043 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) DUF2296 PF10058.4 EAU82005.1 - 0.074 12.8 0.0 15 5.4 0.0 3.5 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) tRNA-synt_1b PF00579.20 EAU82006.2 - 3.2e-75 252.9 0.0 4e-75 252.6 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) F-box-like PF12937.2 EAU82007.1 - 1.4e-07 31.1 0.9 4.2e-07 29.5 0.1 2.2 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU82008.1 - 0.013 15.1 0.3 0.046 13.4 0.2 2.0 1 0 0 1 1 1 0 F-box-like Cellulase PF00150.13 EAU82009.1 - 7.2e-12 45.0 0.0 5.9e-09 35.5 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.2 EAU82011.2 - 2.7e-05 23.8 0.1 8.2e-05 22.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like Glyco_transf_28 PF03033.15 EAU82012.2 - 6.6e-20 71.2 0.0 2.5e-19 69.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EAU82012.2 - 0.00028 19.5 0.3 0.00056 18.5 0.2 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PRANC PF09372.5 EAU82014.1 - 0.00026 20.9 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 PRANC domain F-box PF00646.28 EAU82014.1 - 0.0028 17.2 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU82014.1 - 0.017 14.8 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like Dioxygenase_C PF00775.16 EAU82014.1 - 0.087 12.0 0.4 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Dioxygenase GHL13 PF14883.1 EAU82015.1 - 0.11 11.6 1.5 0.26 10.3 1.0 1.5 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 13 PIF1 PF05970.9 EAU82018.2 - 2.1e-30 105.8 0.0 3.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAU82018.2 - 5.9e-09 35.7 0.1 5.5e-08 32.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 EAU82018.2 - 1.2e-05 25.1 0.1 5.8e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_16 PF13191.1 EAU82018.2 - 0.00058 19.9 0.0 0.041 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Herpes_Helicase PF02689.9 EAU82018.2 - 0.0054 14.5 0.0 0.0089 13.8 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EAU82018.2 - 0.025 14.7 0.0 0.074 13.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EAU82018.2 - 0.08 12.4 2.4 0.49 9.8 0.0 3.2 4 1 0 4 4 4 0 Viral (Superfamily 1) RNA helicase Ribosomal_S18 PF01084.15 EAU82019.2 - 0.087 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S18 TP2 PF01254.13 EAU82020.2 - 1.5 9.1 10.0 1.7 8.9 6.9 1.2 1 0 0 1 1 1 0 Nuclear transition protein 2 DUF4588 PF15251.1 EAU82024.2 - 0.014 15.3 2.8 0.026 14.5 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) DUF346 PF03984.8 EAU82024.2 - 0.044 13.2 0.1 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) Alpha_kinase PF02816.13 EAU82028.2 - 2.1e-16 60.1 0.0 3.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family HypA PF01155.14 EAU82028.2 - 1.7 8.3 9.6 5.8 6.6 1.3 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EAU82028.2 - 7.9 6.3 8.9 19 5.1 6.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon KxDL PF10241.4 EAU82033.2 - 0.0014 18.5 1.0 0.0017 18.2 0.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DASH_Duo1 PF08651.5 EAU82033.2 - 0.032 13.7 0.6 0.049 13.2 0.4 1.3 1 0 0 1 1 1 0 DASH complex subunit Duo1 RmuC PF02646.11 EAU82033.2 - 0.038 12.8 0.2 0.039 12.7 0.1 1.0 1 0 0 1 1 1 0 RmuC family ATP-synt_B PF00430.13 EAU82033.2 - 0.041 13.6 0.1 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4582 PF15189.1 EAU82033.2 - 0.047 12.9 0.3 0.068 12.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4582) LamB_YcsF PF03746.11 EAU82033.2 - 0.075 12.1 0.1 0.081 11.9 0.1 1.1 1 0 0 1 1 1 0 LamB/YcsF family LdpA_C PF12617.3 EAU82033.2 - 0.11 11.7 0.1 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal Baculo_PEP_C PF04513.7 EAU82033.2 - 0.12 12.2 0.2 0.14 12.0 0.2 1.0 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.8 EAU82033.2 - 0.12 12.1 2.1 0.16 11.7 1.5 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 EAU82033.2 - 0.13 12.0 0.9 0.16 11.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ada3 PF10198.4 EAU82033.2 - 0.25 11.1 3.9 1.5 8.5 0.4 2.1 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 UPF0184 PF03670.8 EAU82033.2 - 0.25 11.5 1.9 2.6 8.2 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF972 PF06156.8 EAU82033.2 - 0.57 10.5 3.1 1.2 9.4 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Rad60-SLD_2 PF13881.1 EAU82036.1 - 6.2e-12 45.3 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EAU82036.1 - 0.023 14.0 0.0 0.066 12.6 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family DUF2407 PF10302.4 EAU82036.1 - 0.05 13.7 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF566 PF04484.7 EAU82039.2 - 1.1 8.7 11.4 1.8 7.9 7.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) MFS_1 PF07690.11 EAU82040.2 - 1.3e-30 106.3 28.2 3.4e-30 104.9 19.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Iron_permease PF04120.7 EAU82040.2 - 0.15 11.5 0.3 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Low affinity iron permease Enkurin PF13864.1 EAU82040.2 - 0.53 10.5 0.1 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 Calmodulin-binding MMPL PF03176.10 EAU82040.2 - 0.84 8.2 5.7 0.82 8.3 0.7 2.4 2 0 0 2 2 2 0 MMPL family APH PF01636.18 EAU82041.1 - 0.02 14.6 0.6 0.19 11.4 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Rrn6 PF10214.4 EAU82045.1 - 3.9 5.4 9.6 2.8 5.9 5.7 1.4 1 1 1 2 2 2 0 RNA polymerase I-specific transcription-initiation factor adh_short PF00106.20 EAU82046.1 - 5.2e-06 26.4 0.6 2.5e-05 24.2 0.1 2.3 2 2 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU82046.1 - 0.00016 21.4 0.8 1.1 9.0 0.1 3.1 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU82046.1 - 0.022 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Caudo_TAP PF02413.12 EAU82046.1 - 0.076 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF3391 PF11871.3 EAU82049.1 - 0.15 12.2 8.0 0.14 12.3 0.9 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) THUMP PF02926.12 EAU82049.1 - 0.16 11.8 5.0 13 5.6 2.4 2.8 2 1 1 3 3 3 0 THUMP domain AAA_23 PF13476.1 EAU82049.1 - 0.34 11.2 8.3 0.89 9.8 3.5 2.2 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.1 EAU82049.1 - 0.44 9.4 6.8 0.16 10.9 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Prefoldin PF02996.12 EAU82049.1 - 5.3 6.7 13.3 3.3 7.3 3.3 3.5 3 0 0 3 3 3 0 Prefoldin subunit LcrG PF07216.7 EAU82049.1 - 9.9 6.2 9.6 1.3 9.1 2.5 2.4 2 0 0 2 2 2 0 LcrG protein TFIIA PF03153.8 EAU82050.1 - 1.2 8.9 16.1 1.5 8.6 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EAU82050.1 - 7 4.4 20.9 8.2 4.1 14.5 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1092 PF06485.6 EAU82051.2 - 0.043 12.7 1.3 0.069 12.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) TTSSLRR PF12468.3 EAU82051.2 - 1.7 8.2 4.8 8 6.0 0.5 2.6 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein Citrate_synt PF00285.16 EAU82052.2 - 4.4e-18 65.1 0.1 3.3e-16 58.9 0.0 2.6 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EAU82052.2 - 1.6e-15 57.0 0.0 3.8e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EAU82052.2 - 2e-11 44.2 0.0 5.8e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 EAU82052.2 - 3.5e-09 36.3 0.0 6.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EAU82052.2 - 1.8e-05 24.3 0.0 8.5e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DUF3618 PF12277.3 EAU82055.1 - 1.7 8.7 6.2 3.8 7.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DNA_pol_phi PF04931.8 EAU82056.1 - 0.041 11.6 14.0 0.054 11.2 9.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_60s PF00428.14 EAU82056.1 - 0.24 11.8 5.7 0.76 10.2 3.9 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein NOA36 PF06524.7 EAU82056.1 - 0.41 9.8 7.2 0.88 8.7 5.0 1.5 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.6 EAU82056.1 - 1.1 7.2 3.7 6.9 4.6 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Trypan_PARP PF05887.6 EAU82056.1 - 1.7 8.4 7.8 3.6 7.3 5.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.8 EAU82056.1 - 6 6.6 12.0 11 5.7 8.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.7 EAU82056.1 - 6.2 5.9 12.1 3.9 6.6 6.2 2.0 2 0 0 2 2 2 0 SDA1 GPI-anchored PF10342.4 EAU82057.2 - 0.00019 21.8 0.0 0.00029 21.2 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3042 PF11240.3 EAU82057.2 - 3.5 7.4 8.0 32 4.4 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) FlxA PF14282.1 EAU82058.2 - 0.0083 16.0 0.4 0.027 14.4 0.3 1.8 1 0 0 1 1 1 1 FlxA-like protein Matrilin_ccoil PF10393.4 EAU82058.2 - 0.043 13.1 0.2 0.043 13.1 0.1 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4172 PF13776.1 EAU82058.2 - 0.14 12.2 1.3 1.9 8.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4172) Baculo_PEP_C PF04513.7 EAU82058.2 - 0.19 11.5 2.2 7.1 6.4 0.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EAU82058.2 - 0.84 9.7 3.3 34 4.5 0.1 3.2 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family COG5 PF10392.4 EAU82058.2 - 0.99 9.3 7.4 1.7 8.6 0.2 2.8 3 0 0 3 3 3 0 Golgi transport complex subunit 5 IFT57 PF10498.4 EAU82058.2 - 3.5 6.2 11.0 5.2 5.7 0.2 3.6 3 1 0 3 3 3 0 Intra-flagellar transport protein 57 AAA_13 PF13166.1 EAU82058.2 - 4.7 5.5 10.2 1.2 7.5 3.1 2.4 2 1 0 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.4 EAU82058.2 - 8.7 6.2 19.0 0.27 11.0 2.6 3.2 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 2OG-FeII_Oxy_3 PF13640.1 EAU82059.1 - 2.3e-05 24.8 0.0 0.00011 22.6 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAU82059.1 - 0.0041 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EAU82060.2 - 1.9e-34 119.0 0.0 4e-34 117.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU82062.2 - 2.9e-23 82.1 0.0 5.1e-23 81.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF563 PF04577.9 EAU82063.2 - 0.00012 22.0 0.1 0.00037 20.4 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Laminin_II PF06009.7 EAU82063.2 - 0.0073 16.0 3.1 0.25 11.0 0.1 2.8 2 1 1 3 3 3 2 Laminin Domain II CCDC-167 PF15188.1 EAU82063.2 - 0.3 11.0 14.0 0.11 12.4 0.9 3.5 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 DUF2935 PF11155.3 EAU82064.1 - 0.075 13.1 1.8 1 9.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) NPV_P10 PF05531.7 EAU82064.1 - 0.094 12.9 3.7 30 4.9 0.2 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 EAU82064.1 - 0.18 12.2 9.8 0.63 10.4 0.5 3.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 EAU82064.1 - 1.3 6.7 11.5 0.034 12.0 2.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family E2R135 PF11570.3 EAU82064.1 - 1.4 9.0 6.9 0.13 12.2 0.7 2.2 3 0 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 Occludin_ELL PF07303.8 EAU82064.1 - 1.7 9.4 12.7 2.1 9.1 0.1 3.7 4 1 0 4 4 4 0 Occludin homology domain XhlA PF10779.4 EAU82064.1 - 3.7 7.5 14.9 1.8 8.4 0.1 4.2 4 0 0 4 4 4 0 Haemolysin XhlA CCDC-167 PF15188.1 EAU82064.1 - 6.2 6.8 17.0 0.92 9.4 3.7 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 RPA_interact_N PF14766.1 EAU82065.2 - 3.2 7.2 9.4 1.3 8.5 3.2 2.3 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Cutinase PF01083.17 EAU82066.1 - 1.1e-42 145.8 0.0 1.4e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EAU82066.1 - 1.3e-05 24.7 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EAU82066.1 - 1.7e-05 24.3 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_9 PF10081.4 EAU82066.1 - 0.0013 17.4 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family DUF2974 PF11187.3 EAU82066.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EAU82066.1 - 0.0082 15.9 0.1 0.0098 15.6 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EAU82066.1 - 0.022 15.0 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain VirJ PF06057.6 EAU82066.1 - 0.054 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EAU82066.1 - 0.067 12.6 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EAU82066.1 - 0.12 11.9 0.9 0.58 9.6 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold F-box-like PF12937.2 EAU82068.1 - 0.0024 17.5 0.0 0.0087 15.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like Nop14 PF04147.7 EAU82069.2 - 0.17 9.7 8.9 0.24 9.2 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EAU82071.2 - 1.4e-09 37.4 0.0 9.1e-05 21.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82071.2 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase UPF0506 PF11703.3 EAU82075.2 - 0.56 10.2 8.9 3.6 7.6 2.5 3.1 2 1 1 3 3 3 0 UPF0506 Zn_clus PF00172.13 EAU82075.2 - 0.84 9.5 9.4 3 7.8 0.6 2.3 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_18 PF13238.1 EAU82081.2 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1269 PF06897.7 EAU82081.2 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) PIF1 PF05970.9 EAU82082.1 - 6.6e-07 28.6 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAU82082.1 - 9.8e-05 22.0 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU82082.1 - 0.0033 17.1 0.0 0.008 15.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EAU82082.1 - 0.0058 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.12 EAU82082.1 - 0.089 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MFS_1 PF07690.11 EAU82087.2 - 4.3e-19 68.4 27.2 4.3e-19 68.4 18.9 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily HpcH_HpaI PF03328.9 EAU82088.1 - 6.8e-31 106.8 0.0 1.3e-29 102.7 0.0 2.0 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EAU82088.1 - 0.034 13.3 0.1 0.44 9.7 0.1 2.1 1 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase PK PF00224.16 EAU82088.1 - 0.047 12.3 0.0 2 6.9 0.0 2.0 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain FlpD PF02662.11 EAU82088.1 - 0.099 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit adh_short_C2 PF13561.1 EAU82090.2 - 2.8e-12 46.9 0.1 1.8e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU82090.2 - 6.7e-08 32.6 3.6 1.1e-07 31.8 2.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU82090.2 - 0.00095 18.8 0.4 0.0016 18.1 0.3 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAU82090.2 - 0.053 13.3 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peroxin-13_N PF04088.8 EAU82091.1 - 1.3e-41 142.2 0.0 1.8e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EAU82091.1 - 2.8e-11 42.7 0.0 5.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAU82091.1 - 1.5e-09 37.0 1.7 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EAU82091.1 - 4.7e-08 32.4 1.0 9.6e-08 31.4 0.7 1.6 1 1 0 1 1 1 1 Variant SH3 domain MAGE_N PF12440.3 EAU82091.1 - 1.1 9.5 13.1 3 8.1 9.1 1.7 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Pkinase PF00069.20 EAU82093.2 - 4e-05 22.8 0.1 0.0002 20.6 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EAU82093.2 - 4.4e-05 23.3 1.8 0.00025 20.8 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU82093.2 - 0.065 12.8 0.1 0.19 11.2 0.0 1.7 1 1 0 2 2 2 0 Choline/ethanolamine kinase Peptidase_C48 PF02902.14 EAU82094.1 - 3.5e-11 43.1 0.0 6.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF904 PF06005.7 EAU82097.1 - 0.057 13.7 0.0 0.07 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF550 PF04447.7 EAU82099.2 - 0.06 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) SGT1 PF07093.6 EAU82099.2 - 0.18 10.1 2.7 0.25 9.6 1.9 1.1 1 0 0 1 1 1 0 SGT1 protein BUD22 PF09073.5 EAU82099.2 - 1.1 8.2 4.7 1.5 7.8 3.3 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 EAU82099.2 - 1.9 8.0 5.5 2.9 7.4 3.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EAU82099.2 - 5.8 4.6 9.3 8.4 4.1 6.4 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EAU82101.2 - 9.2e-05 21.7 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EAU82101.2 - 0.0029 17.3 0.0 0.021 14.5 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF466 PF04328.8 EAU82102.2 - 0.06 13.1 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF466) WD40 PF00400.27 EAU82103.2 - 1.5e-163 525.5 56.1 3.4e-13 48.9 0.2 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat Gmad1 PF10647.4 EAU82103.2 - 2.9e-18 66.2 1.5 0.0013 18.1 0.2 6.8 2 2 2 5 5 5 4 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EAU82103.2 - 5.2e-15 54.7 21.2 1.4 8.6 0.0 14.0 14 0 0 14 14 14 1 WD40-like Beta Propeller Repeat NACHT PF05729.7 EAU82103.2 - 4.3e-09 36.2 0.0 8.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU82103.2 - 2.1e-06 27.8 0.0 7.4e-06 26.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF3312 PF11768.3 EAU82103.2 - 1.9e-05 23.0 0.0 3.2 5.8 0.0 5.6 6 1 2 8 8 8 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EAU82103.2 - 3.2e-05 22.8 6.0 0.022 13.5 0.1 5.1 1 1 3 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.1 EAU82103.2 - 0.00013 21.1 5.2 4 6.4 0.0 7.3 3 2 6 9 9 9 2 Neuroblastoma-amplified sequence, N terminal KAP_NTPase PF07693.9 EAU82103.2 - 0.0012 17.9 0.0 0.0031 16.5 0.0 1.7 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 EAU82103.2 - 0.0018 18.4 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.11 EAU82103.2 - 0.0092 14.3 0.3 0.41 8.9 0.0 3.6 2 1 0 4 4 4 1 Cytochrome D1 heme domain Peptidase_S9_N PF02897.10 EAU82103.2 - 0.024 13.2 0.0 38 2.7 0.0 4.3 3 2 1 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ PF01011.16 EAU82103.2 - 0.027 13.9 0.3 1.1 8.9 0.1 3.5 4 0 0 4 4 3 0 PQQ enzyme repeat AAA_17 PF13207.1 EAU82103.2 - 0.041 14.6 0.1 0.24 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EAU82103.2 - 0.086 11.6 0.0 4.9 5.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EAU82103.2 - 0.09 12.9 0.0 0.37 10.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase PQQ_3 PF13570.1 EAU82103.2 - 0.17 12.2 8.2 4.9 7.5 0.6 5.8 6 0 0 6 6 5 0 PQQ-like domain SopA PF13981.1 EAU82103.2 - 0.41 10.6 0.0 0.84 9.6 0.0 1.4 1 0 0 1 1 1 0 SopA-like central domain CHAT PF12770.2 EAU82104.2 - 4.9e-26 91.5 0.0 8.2e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain Mob1_phocein PF03637.12 EAU82105.1 - 1.7e-26 92.9 0.0 2.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family SET PF00856.23 EAU82110.2 - 0.03 14.6 0.1 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 SET domain DUF2945 PF11160.3 EAU82110.2 - 0.05 13.4 1.0 0.05 13.4 0.7 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2945) DUF2097 PF09870.4 EAU82110.2 - 0.059 13.4 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2097) Med3 PF11593.3 EAU82110.2 - 4 6.5 17.2 5.6 6.1 11.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pro_isomerase PF00160.16 EAU82113.1 - 2.4e-47 160.9 0.6 2.7e-47 160.8 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AA_permease_2 PF13520.1 EAU82114.2 - 1.9e-69 234.2 32.2 1.9e-69 234.2 22.3 1.4 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EAU82114.2 - 8.1e-20 70.5 23.2 1.2e-19 69.9 16.1 1.2 1 0 0 1 1 1 1 Amino acid permease Dioxygenase_C PF00775.16 EAU82116.2 - 3.9e-52 176.1 0.0 5.8e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EAU82116.2 - 1.7e-19 69.5 0.0 3.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EAU82116.2 - 0.00086 19.3 0.1 0.0058 16.6 0.0 2.4 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF563 PF04577.9 EAU82118.2 - 1.2e-23 84.0 0.1 5.7e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Toxin_43 PF15604.1 EAU82119.1 - 0.022 14.8 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative toxin 43 DUF4226 PF10774.4 EAU82119.1 - 0.38 10.8 2.2 0.86 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF563 PF04577.9 EAU82121.2 - 3.3e-23 82.7 0.1 3.3e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF4222 PF13973.1 EAU82122.1 - 0.17 11.3 0.3 0.52 9.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) JAB PF01398.16 EAU82123.2 - 5.8e-25 87.2 0.0 1.2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EAU82123.2 - 3.6e-05 23.2 0.0 7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Amidase PF01425.16 EAU82124.2 - 7e-69 232.7 0.0 1.4e-68 231.8 0.0 1.5 1 1 0 1 1 1 1 Amidase DUF3328 PF11807.3 EAU82125.1 - 1.9e-19 70.2 0.0 2.3e-19 69.9 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) TPPK_C PF12555.3 EAU82126.1 - 0.16 11.7 0.2 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF287 PF03384.9 EAU82126.1 - 1.3 9.2 4.3 1.6 8.9 2.0 1.8 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 DUF3328 PF11807.3 EAU82127.2 - 6.2e-22 78.3 0.1 7.1e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Flagellin_N PF00669.15 EAU82128.1 - 0.08 12.7 1.4 0.12 12.1 0.9 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FHA PF00498.21 EAU82129.1 - 2.6e-13 49.8 0.0 4.2e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 FHA domain Ribonucleas_3_3 PF14622.1 EAU82130.1 - 4.5e-13 49.2 0.0 6.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like GP4 PF03010.9 EAU82130.1 - 0.12 11.9 0.1 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 GP4 WD40 PF00400.27 EAU82131.1 - 3.3e-130 419.8 30.1 3.6e-14 52.0 0.0 10.6 10 0 0 10 10 10 10 WD domain, G-beta repeat PD40 PF07676.7 EAU82131.1 - 2e-16 59.2 19.8 6.6 6.5 0.0 12.3 12 0 0 12 12 12 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EAU82131.1 - 7.7e-14 51.6 20.5 7e-06 25.6 0.0 5.2 3 1 2 6 6 6 4 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 EAU82131.1 - 1.7e-10 40.8 0.0 3.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Nucleoporin_N PF08801.6 EAU82131.1 - 1.6e-09 37.0 0.5 0.069 11.8 0.1 4.7 1 1 2 3 3 3 3 Nup133 N terminal like AAA_16 PF13191.1 EAU82131.1 - 2e-08 34.4 0.1 8.4e-08 32.4 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.1 EAU82131.1 - 7.3e-08 32.1 1.8 0.021 14.2 0.1 4.6 1 1 3 5 5 5 4 PQQ-like domain DUF374 PF04028.8 EAU82131.1 - 8.8e-05 21.6 4.1 13 5.0 0.0 7.0 1 1 7 8 8 8 0 Domain of unknown function (DUF374) AAA_22 PF13401.1 EAU82131.1 - 0.00094 19.3 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain Peptidase_S9_N PF02897.10 EAU82131.1 - 0.002 16.7 0.3 21 3.5 0.0 5.6 1 1 8 9 9 9 0 Prolyl oligopeptidase, N-terminal beta-propeller domain KAP_NTPase PF07693.9 EAU82131.1 - 0.0028 16.7 1.4 0.0053 15.7 0.4 1.7 1 1 1 2 2 2 1 KAP family P-loop domain DUF3312 PF11768.3 EAU82131.1 - 0.0069 14.6 0.0 48 1.9 0.0 4.6 1 1 7 8 8 8 0 Protein of unknown function (DUF3312) Me-amine-dh_H PF06433.6 EAU82131.1 - 0.03 12.9 0.0 44 2.5 0.0 4.4 1 1 6 8 8 8 0 Methylamine dehydrogenase heavy chain (MADH) APS_kinase PF01583.15 EAU82131.1 - 0.032 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 EAU82131.1 - 0.14 13.0 0.0 0.51 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU82131.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAU82131.1 - 0.22 11.4 0.0 6.1 6.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain Arch_fla_DE PF04659.8 EAU82131.1 - 0.22 11.3 0.0 0.54 10.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal flagella protein Pkinase PF00069.20 EAU82133.2 - 0.00014 21.1 0.0 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EAU82133.2 - 0.013 15.2 1.8 0.024 14.3 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family TOMM6 PF15184.1 EAU82136.2 - 0.082 12.2 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog HTH_IclR PF09339.5 EAU82137.2 - 0.26 10.9 1.4 9.2 5.9 0.0 2.5 2 0 0 2 2 2 0 IclR helix-turn-helix domain Ammonium_transp PF00909.16 EAU82143.2 - 5.4e-113 377.4 33.5 6.1e-106 354.2 16.8 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family PLAC8 PF04749.12 EAU82149.2 - 1e-16 61.4 0.2 1.5e-16 60.8 0.1 1.3 1 0 0 1 1 1 1 PLAC8 family Ammonium_transp PF00909.16 EAU82151.2 - 8.6e-107 357.0 28.4 5.2e-58 196.4 10.6 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family WD40 PF00400.27 EAU82152.2 - 4.2e-81 264.2 33.0 3.7e-14 51.9 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat NACHT PF05729.7 EAU82152.2 - 1.7e-10 40.8 0.0 3.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU82152.2 - 1.6e-08 34.7 0.2 5.3e-08 33.0 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 EAU82152.2 - 5.3e-07 29.1 14.4 9.7 5.9 0.0 8.3 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 EAU82152.2 - 0.00067 19.8 0.1 0.0027 17.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain KAP_NTPase PF07693.9 EAU82152.2 - 0.0029 16.6 1.4 0.0058 15.6 0.4 1.7 1 1 1 2 2 2 1 KAP family P-loop domain DUF3312 PF11768.3 EAU82152.2 - 0.012 13.8 0.0 1.9 6.6 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3312) APS_kinase PF01583.15 EAU82152.2 - 0.031 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 EAU82152.2 - 0.039 14.7 0.1 0.22 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Flt3_lig PF02947.9 EAU82152.2 - 0.092 12.6 0.0 10 5.9 0.0 3.5 2 1 2 4 4 4 0 flt3 ligand AAA_18 PF13238.1 EAU82152.2 - 0.17 12.1 0.0 0.43 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAU82152.2 - 0.19 11.6 0.0 6 6.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Helitron_like_N PF14214.1 EAU82153.2 - 7.9e-10 38.7 0.0 1.5e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3938 PF13074.1 EAU82153.2 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) FAD_binding_4 PF01565.18 EAU82165.2 - 2.3e-20 72.4 1.1 4.3e-20 71.5 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU82165.2 - 1.2e-07 31.5 0.2 3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Gly-zipper_OmpA PF13436.1 EAU82165.2 - 0.023 14.3 0.4 0.056 13.1 0.2 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DAP10 PF07213.6 EAU82165.2 - 0.15 11.8 0.3 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 DAP10 membrane protein Ras PF00071.17 EAU82166.2 - 5.1e-28 97.4 0.0 8.2e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Pkinase PF00069.20 EAU82166.2 - 4.3e-27 94.8 0.0 6.8e-17 61.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82166.2 - 3.2e-23 82.1 0.0 2e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Miro PF08477.8 EAU82166.2 - 7.2e-13 49.0 0.0 1.4e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU82166.2 - 0.00032 19.9 0.0 0.00052 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EAU82166.2 - 0.0072 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EAU82166.2 - 0.026 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EAU82166.2 - 0.09 12.1 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EAU82166.2 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EAU82166.2 - 0.17 11.8 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase VSP PF03302.8 EAU82167.2 - 0.05 12.2 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein PepSY_TM_2 PF13703.1 EAU82168.2 - 0.036 14.2 0.7 0.089 12.9 0.2 1.8 2 0 0 2 2 2 0 PepSY-associated TM helix Herpes_gE PF02480.11 EAU82168.2 - 0.037 12.3 0.0 0.052 11.8 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EAU82168.2 - 0.17 11.4 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Lamp PF01299.12 EAU82168.2 - 5.9 5.9 5.9 3.8 6.5 0.8 2.3 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) FMN_red PF03358.10 EAU82169.2 - 3.3e-08 33.1 0.1 4.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EAU82169.2 - 7.3e-05 22.7 0.3 0.00033 20.6 0.2 2.0 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EAU82169.2 - 0.00058 19.4 0.1 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 EAU82170.1 - 1.1e-09 38.4 0.4 3.1e-09 36.9 0.3 2.0 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EAU82170.1 - 1.9e-08 33.9 0.0 2.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EAU82170.1 - 1.3e-05 24.8 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold AdoMet_MTase PF07757.8 EAU82171.1 - 4.7e-34 116.8 0.1 6.4e-33 113.2 0.0 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EAU82171.1 - 9.3e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EAU82171.1 - 0.031 13.9 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EAU82171.1 - 0.11 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EAU82171.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EAU82171.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Aldose_epim PF01263.15 EAU82172.2 - 5.5e-51 173.4 0.0 3.5e-49 167.5 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase NIF3 PF01784.13 EAU82172.2 - 0.16 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) IL13 PF03487.8 EAU82173.1 - 0.11 12.1 0.5 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Interleukin-13 DUF2749 PF10907.3 EAU82174.1 - 0.024 14.4 1.0 0.062 13.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF3879 PF12995.2 EAU82177.2 - 0.11 12.0 0.1 0.3 10.6 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) Ribosomal_L18ae PF01775.12 EAU82178.1 - 6.3e-58 194.0 0.4 7.8e-58 193.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain ATP_synth_reg PF14960.1 EAU82181.2 - 0.099 11.8 0.2 0.31 10.2 0.2 1.8 1 0 0 1 1 1 0 ATP synthase regulation DUF2264 PF10022.4 EAU82182.2 - 8.5e-135 449.0 0.4 1.2e-134 448.6 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) PLAC8 PF04749.12 EAU82184.2 - 3.9e-26 91.6 14.4 4.7e-26 91.4 10.0 1.1 1 0 0 1 1 1 1 PLAC8 family HTH_21 PF13276.1 EAU82186.2 - 0.0072 16.3 0.1 3.9 7.5 0.0 2.6 2 0 0 2 2 2 2 HTH-like domain GST_N_3 PF13417.1 EAU82189.1 - 2e-13 50.3 0.0 4.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU82189.1 - 1.7e-11 43.9 0.0 3.2e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAU82189.1 - 3.3e-05 23.9 0.0 6.5e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EAU82189.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 EAU82189.1 - 0.0033 17.2 0.4 0.0092 15.8 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_S8 PF00082.17 EAU82190.1 - 9.2e-47 159.5 21.4 1.3e-46 159.0 14.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAU82190.1 - 4.6e-08 33.5 0.0 1.9e-06 28.3 0.0 2.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 F-box-like PF12937.2 EAU82193.1 - 0.0027 17.3 0.2 0.0065 16.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like WSS_VP PF12175.3 EAU82196.2 - 0.063 12.3 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP RELT PF12606.3 EAU82196.2 - 0.84 8.8 2.9 16 4.7 0.2 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Trypan_PARP PF05887.6 EAU82196.2 - 1.5 8.5 4.1 2.7 7.8 2.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Trp_DMAT PF11991.3 EAU82198.2 - 2.1e-38 132.4 0.0 2e-36 125.9 0.0 2.7 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase MFS_1 PF07690.11 EAU82199.2 - 8.5e-38 129.9 26.5 8.5e-38 129.9 18.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_DMAT PF11991.3 EAU82200.1 - 2.2e-46 158.7 0.0 5.1e-46 157.5 0.0 1.6 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Ricin_B_lectin PF00652.17 EAU82201.2 - 4e-16 59.1 0.6 7.1e-16 58.3 0.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU82201.2 - 9.3e-11 42.0 0.1 3e-10 40.3 0.1 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_61 PF03443.9 EAU82202.1 - 1.7e-39 135.9 0.0 2e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 EAU82202.1 - 0.052 13.6 0.9 0.28 11.2 0.0 2.5 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_6 PF01341.12 EAU82203.1 - 2.1e-92 309.7 0.9 2.7e-92 309.3 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Peptidase_S8 PF00082.17 EAU82204.2 - 4.9e-44 150.5 16.0 6.7e-44 150.1 11.1 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAU82204.2 - 2.1e-08 34.5 0.0 5.5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 TT_ORF1 PF02956.9 EAU82206.1 - 3.7 5.8 9.2 4.4 5.6 6.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 TMEM154 PF15102.1 EAU82207.1 - 0.0038 16.9 0.2 0.0078 15.9 0.0 1.6 2 0 0 2 2 2 1 TMEM154 protein family DUF2562 PF10814.3 EAU82207.1 - 0.016 15.1 1.2 0.029 14.3 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) ETRAMP PF09716.5 EAU82207.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_gE PF02480.11 EAU82207.1 - 0.037 12.2 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EAU82207.1 - 0.059 13.7 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3169 PF11368.3 EAU82207.1 - 0.061 12.5 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF1469 PF07332.6 EAU82207.1 - 0.074 12.7 2.2 0.15 11.7 1.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) DUF4366 PF14283.1 EAU82207.1 - 0.079 12.3 0.1 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) stn_TNFRSF12A PF12191.3 EAU82207.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF4597 PF15366.1 EAU82207.1 - 0.15 11.6 1.6 7.6 6.2 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4597) PGI PF00342.14 EAU82208.1 - 5.2e-214 711.1 0.2 5.9e-214 710.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CFEM PF05730.6 EAU82209.1 - 0.00026 20.7 7.1 0.00026 20.7 4.9 2.7 2 1 0 2 2 2 1 CFEM domain CFEM PF05730.6 EAU82212.2 - 4.9e-05 23.0 3.6 8.7e-05 22.2 2.5 1.4 1 0 0 1 1 1 1 CFEM domain Peptidase_S8 PF00082.17 EAU82213.1 - 1.3e-47 162.2 21.4 1.9e-47 161.7 14.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAU82213.1 - 2.1e-09 37.8 0.1 6.2e-08 33.0 0.1 2.4 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF4275 PF14101.1 EAU82215.1 - 0.015 15.3 1.6 0.026 14.6 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) 7TM_GPCR_Sru PF10322.4 EAU82217.2 - 0.017 14.2 0.9 0.022 13.8 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Neil1-DNA_bind PF09292.5 EAU82218.2 - 0.021 14.6 0.4 0.21 11.4 0.0 2.7 3 0 0 3 3 3 0 Endonuclease VIII-like 1, DNA bind BBE PF08031.7 EAU82222.2 - 7.8e-09 35.3 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EAU82222.2 - 6.8e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GST_N_3 PF13417.1 EAU82225.1 - 5.6e-11 42.5 0.0 1.5e-10 41.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU82225.1 - 3.1e-09 36.6 0.0 6.5e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU82225.1 - 0.00092 19.1 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU82225.1 - 0.0048 16.7 0.1 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tic20 PF09685.5 EAU82235.1 - 0.33 10.9 9.7 0.58 10.1 0.3 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF788 PF05620.6 EAU82235.1 - 2 8.2 4.4 2.6 7.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) FHA PF00498.21 EAU82236.2 - 4.3e-17 61.9 0.0 1.1e-16 60.7 0.0 1.7 1 1 1 2 2 2 1 FHA domain IncA PF04156.9 EAU82236.2 - 2.8e-05 23.8 0.0 0.0018 17.9 0.0 2.4 2 1 1 3 3 3 1 IncA protein DUF1183 PF06682.7 EAU82236.2 - 0.12 12.0 1.9 0.22 11.0 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) CAP_N PF01213.14 EAU82236.2 - 0.53 9.5 4.0 1 8.5 2.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF972 PF06156.8 EAU82236.2 - 1.8 8.9 7.5 0.52 10.6 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) PAPA-1 PF04795.7 EAU82238.2 - 3.4e-13 50.1 6.1 3.4e-13 50.1 4.2 5.1 5 1 0 5 5 5 2 PAPA-1-like conserved region DUF3602 PF12223.3 EAU82241.2 - 1.5e-25 89.3 31.3 2e-08 34.4 2.2 5.7 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) zf-MYND PF01753.13 EAU82242.2 - 2.6e-10 40.0 8.8 6.8e-10 38.6 6.1 1.7 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU82242.2 - 0.055 12.7 3.5 0.13 11.5 2.5 1.6 1 0 0 1 1 1 0 Life-span regulatory factor DUF735 PF05246.6 EAU82243.1 - 0.069 12.8 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF735) Na_K-ATPase PF00287.13 EAU82243.1 - 0.55 8.9 2.6 0.45 9.2 0.1 1.8 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain DUF4405 PF14358.1 EAU82244.1 - 0.57 10.3 4.7 0.16 12.1 0.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Pheromone PF08015.6 EAU82247.1 - 0.0077 17.0 4.0 0.0077 17.0 2.8 2.1 2 1 0 2 2 2 1 Fungal mating-type pheromone SSP160 PF06933.6 EAU82247.1 - 0.079 10.9 4.5 0.11 10.4 3.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4234 PF14018.1 EAU82249.2 - 0.006 16.3 3.1 0.006 16.3 2.2 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4234) HNH_2 PF13391.1 EAU82257.2 - 0.024 14.4 0.1 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 HNH endonuclease Glyco_hydro_11 PF00457.12 EAU82258.1 - 9.6e-74 246.6 21.1 1.1e-73 246.4 14.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Toxin_49 PF15529.1 EAU82258.1 - 0.096 12.6 0.1 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 Putative toxin 49 DEAD PF00270.24 EAU82260.2 - 3.9e-15 55.7 0.0 6.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU82260.2 - 1.8e-10 40.5 0.0 4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EAU82260.2 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain F-box-like PF12937.2 EAU82261.1 - 2.3e-07 30.4 2.1 7.7e-07 28.7 1.5 2.0 1 1 0 1 1 1 1 F-box-like GNAT_acetyltr_2 PF13718.1 EAU82262.2 - 2.1e-73 245.8 0.0 4e-73 244.9 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EAU82262.2 - 2.4e-59 199.9 0.1 1.3e-58 197.5 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EAU82262.2 - 6.8e-39 131.4 0.4 1.7e-38 130.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EAU82262.2 - 5e-31 106.7 0.0 2.2e-30 104.7 0.0 2.2 2 0 0 2 2 2 1 Possible tRNA binding domain Acetyltransf_1 PF00583.19 EAU82262.2 - 0.0043 17.0 0.1 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU82262.2 - 0.0058 16.7 0.0 0.048 13.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain eIF3_N PF09440.5 EAU82264.1 - 2.5e-44 150.6 2.0 8.8e-43 145.6 1.7 2.8 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EAU82264.1 - 2.1e-10 40.8 0.1 8.5e-10 38.8 0.1 2.1 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EAU82264.1 - 0.00042 20.0 0.4 0.0014 18.4 0.0 2.0 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 CagZ PF09053.5 EAU82264.1 - 0.008 15.5 0.2 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 CagZ zf-C2H2 PF00096.21 EAU82265.2 - 6e-10 38.8 9.3 9.3e-05 22.5 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU82265.2 - 1.5e-06 28.1 7.7 0.00027 21.0 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU82265.2 - 0.00017 21.7 10.5 0.031 14.5 0.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EAU82265.2 - 0.11 12.2 7.7 1.9 8.2 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EAU82265.2 - 0.13 12.4 1.3 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Hydrolase_6 PF13344.1 EAU82267.1 - 1.9e-13 50.1 0.0 3.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU82267.1 - 2.2e-09 36.9 0.0 4.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EAU82267.1 - 0.015 15.4 0.0 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3185 PF11381.3 EAU82267.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) PLAC8 PF04749.12 EAU82268.2 - 3.3e-25 88.7 8.8 4e-25 88.4 6.1 1.1 1 0 0 1 1 1 1 PLAC8 family Extensin_2 PF04554.8 EAU82268.2 - 0.46 10.3 33.6 0.31 10.9 17.9 2.9 2 1 0 2 2 2 0 Extensin-like region DnaJ PF00226.26 EAU82269.1 - 4e-20 71.3 0.4 4e-20 71.3 0.3 2.3 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 EAU82269.1 - 1.7e-18 66.0 6.8 2.8e-13 49.3 0.1 5.5 4 2 1 6 6 6 3 TPR repeat TPR_1 PF00515.23 EAU82269.1 - 5.2e-15 54.3 1.3 0.00033 20.1 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU82269.1 - 1.4e-13 49.6 11.8 0.00078 19.1 0.0 6.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EAU82269.1 - 3e-13 49.8 3.3 0.00043 20.5 0.0 5.4 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAU82269.1 - 1.3e-11 44.8 15.0 1e-06 29.2 0.0 5.3 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAU82269.1 - 2.9e-11 42.9 4.6 0.021 15.4 0.0 6.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAU82269.1 - 7.2e-09 35.1 0.4 0.014 15.5 0.1 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU82269.1 - 3e-08 33.6 6.5 7.3e-06 26.0 0.5 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EAU82269.1 - 1.3e-07 31.3 0.1 0.13 12.7 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU82269.1 - 1.6e-07 30.6 8.1 0.26 11.1 0.0 6.5 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU82269.1 - 1.1e-06 28.4 4.9 0.013 15.4 0.3 4.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU82269.1 - 5.9e-06 25.6 2.6 0.069 12.9 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAU82269.1 - 7.2e-06 26.1 6.4 5.4 7.6 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAU82269.1 - 4.6e-05 23.1 3.9 0.0022 17.8 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat DUF3808 PF10300.4 EAU82269.1 - 0.0027 16.3 0.1 0.0076 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) Thioredoxin_8 PF13905.1 EAU82269.1 - 0.046 13.8 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 1 0 Thioredoxin-like TPR_20 PF14561.1 EAU82269.1 - 2.2 8.4 7.4 1.2 9.3 0.0 3.8 4 1 1 5 5 3 0 Tetratricopeptide repeat AcetylCoA_hydro PF02550.10 EAU82276.1 - 2.5e-41 141.6 0.0 3.9e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EAU82276.1 - 9.4e-40 135.7 0.0 1.4e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DUF4029 PF13221.1 EAU82277.2 - 0.026 14.8 0.3 0.026 14.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Srg PF02118.16 EAU82277.2 - 0.069 12.5 7.6 0.068 12.5 2.9 1.9 2 0 0 2 2 2 0 Srg family chemoreceptor TraP PF07296.6 EAU82277.2 - 0.22 10.4 1.6 2.8 6.8 0.0 2.2 2 0 0 2 2 2 0 TraP protein Syndecan PF01034.15 EAU82279.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain DUF1049 PF06305.6 EAU82279.1 - 0.047 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) RCR PF12273.3 EAU82279.1 - 0.11 13.0 0.7 0.28 11.7 0.5 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SKG6 PF08693.5 EAU82279.1 - 2.1 7.7 4.5 4.5 6.6 3.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-MYND PF01753.13 EAU82280.2 - 6.2e-10 38.7 11.1 1.1e-09 38.0 7.7 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU82280.2 - 0.033 14.0 4.1 0.066 13.0 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EAU82282.1 - 1.5e-11 43.9 8.5 2.4e-11 43.3 5.9 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU82282.1 - 0.0019 18.0 4.8 0.0035 17.1 3.3 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EAU82284.2 - 3e-07 30.1 12.0 3e-07 30.1 8.3 2.2 2 0 0 2 2 2 1 MYND finger Viral_helicase1 PF01443.13 EAU82284.2 - 0.093 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase F-box-like PF12937.2 EAU82286.2 - 0.013 15.2 0.1 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 EAU82287.2 - 8.7e-32 110.1 29.2 9.6e-32 110.0 19.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1580 PF07618.6 EAU82288.2 - 0.062 12.6 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) HpaP PF09483.5 EAU82289.1 - 1.1 9.1 8.4 1.4 8.8 5.8 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) PetM PF08041.6 EAU82290.2 - 0.16 11.5 2.6 0.31 10.5 1.8 1.5 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 DUF1129 PF06570.6 EAU82293.2 - 1.7 7.9 6.0 0.55 9.5 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1996 PF09362.5 EAU82295.2 - 2.5e-71 240.0 0.0 3.7e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1399 PF07173.7 EAU82297.1 - 0.014 15.7 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) EphA2_TM PF14575.1 EAU82300.2 - 0.0054 17.0 0.0 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EAU82300.2 - 0.009 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF4470 PF14737.1 EAU82305.1 - 2.3e-21 75.4 0.0 4.4e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EAU82305.1 - 7.5e-11 41.7 16.6 1.6e-10 40.6 11.5 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EAU82305.1 - 2.2 8.0 10.0 6.7 6.4 6.9 1.9 1 0 0 1 1 1 0 HIT zinc finger Nop14 PF04147.7 EAU82306.2 - 0.063 11.2 4.9 0.09 10.6 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EAU82306.2 - 0.17 11.1 6.7 0.31 10.2 4.7 1.3 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 EAU82306.2 - 0.21 10.7 4.8 0.33 10.0 3.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3245 PF11595.3 EAU82306.2 - 0.24 11.6 1.9 1.4 9.2 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) CDC45 PF02724.9 EAU82306.2 - 0.73 7.7 3.4 1.1 7.1 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EAU82306.2 - 0.99 8.9 7.5 5.2 6.6 5.2 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.7 EAU82306.2 - 1.6 7.9 5.7 2.5 7.2 4.0 1.2 1 0 0 1 1 1 0 SDA1 EphA2_TM PF14575.1 EAU82308.1 - 0.029 14.7 0.1 0.054 13.8 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EAU82308.1 - 0.076 12.3 1.6 0.14 11.4 1.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1996 PF09362.5 EAU82309.1 - 4.3e-84 281.8 0.1 5.1e-84 281.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CAP_N PF01213.14 EAU82310.2 - 9.7 5.3 7.6 14 4.7 5.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NPR3 PF03666.8 EAU82312.1 - 0.0003 19.4 1.1 0.00038 19.1 0.8 1.0 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 RRM_1 PF00076.17 EAU82321.1 - 6.5e-34 115.3 0.2 2.7e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU82321.1 - 2.2e-28 98.0 0.2 3.8e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU82321.1 - 3.1e-11 42.9 0.2 3e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mucin PF01456.12 EAU82321.1 - 1.8 8.3 25.7 3 7.6 17.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SNO PF01174.14 EAU82322.1 - 4.1e-48 163.5 0.0 4.3e-47 160.1 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EAU82322.1 - 8.7e-10 38.4 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EAU82322.1 - 3.9e-06 26.2 0.1 6.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EAU82322.1 - 2.7e-05 23.9 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.23 EAU82322.1 - 0.0009 18.7 0.3 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EAU82322.1 - 0.00097 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Aldolase PF01081.14 EAU82322.1 - 0.067 12.3 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 KDPG and KHG aldolase BPL_N PF09825.4 EAU82322.1 - 0.11 11.3 0.0 0.55 8.9 0.0 1.8 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal DUF1183 PF06682.7 EAU82325.2 - 0.26 10.8 5.1 0.16 11.5 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) NARP1 PF12569.3 EAU82326.2 - 0.24 10.1 2.8 0.41 9.3 1.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4436 PF14494.1 EAU82328.2 - 6.8e-05 22.2 5.3 0.00012 21.4 3.6 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4436) p450 PF00067.17 EAU82330.1 - 2e-57 194.7 0.0 2.8e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EAU82331.1 - 9.3e-26 91.1 0.1 1.3e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU82331.1 - 4e-16 59.0 0.0 2e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU82331.1 - 5e-14 52.4 0.0 2.3e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.9 EAU82331.1 - 1.8e-05 23.3 0.0 2.4e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Ndr family FSH1 PF03959.8 EAU82331.1 - 0.0031 16.9 0.0 0.041 13.3 0.0 2.4 3 0 0 3 3 3 1 Serine hydrolase (FSH1) EII-Sor PF03609.9 EAU82331.1 - 0.0049 16.1 0.2 0.0084 15.4 0.1 1.3 1 0 0 1 1 1 1 PTS system sorbose-specific iic component DLH PF01738.13 EAU82331.1 - 0.01 15.1 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EAU82331.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Sec63 PF02889.11 EAU82333.1 - 5.3e-28 98.1 0.0 9.3e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EAU82333.1 - 4.6e-17 61.4 0.2 9.9e-17 60.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Methyltransf_2 PF00891.13 EAU82335.1 - 2.8e-35 121.6 0.0 3.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EAU82335.1 - 2.2e-07 31.4 0.0 4.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU82335.1 - 1.9e-05 24.2 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU82335.1 - 0.0034 16.7 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EAU82335.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EAU82335.1 - 0.024 15.1 0.0 0.055 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EAU82335.1 - 0.029 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cpn60_TCP1 PF00118.19 EAU82336.1 - 4.8e-138 460.8 13.0 5.6e-138 460.5 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PMT PF02366.13 EAU82337.2 - 1e-79 267.3 12.3 1e-79 267.3 8.5 2.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EAU82337.2 - 2.4e-44 151.1 0.5 4.7e-44 150.2 0.3 1.5 1 0 0 1 1 1 1 MIR domain DUF1240 PF06836.7 EAU82337.2 - 0.068 13.4 2.8 10 6.4 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) p450 PF00067.17 EAU82339.2 - 1.6e-66 224.7 0.0 2.5e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F_bP_aldolase PF01116.15 EAU82343.1 - 1e-97 326.7 0.0 1.1e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ldh_1_N PF00056.18 EAU82346.1 - 3.3e-44 150.1 0.0 4.8e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EAU82346.1 - 6.5e-42 143.2 0.0 9.7e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EAU82346.1 - 0.0012 17.5 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EAU82346.1 - 0.022 15.0 0.2 0.056 13.7 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EAU82346.1 - 0.027 14.4 0.2 0.05 13.6 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EAU82346.1 - 0.032 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 EAU82346.1 - 0.065 12.5 0.1 2.1 7.6 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Abhydrolase_4 PF08386.5 EAU82347.2 - 5.4e-24 84.0 0.0 1.2e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAU82347.2 - 1.9e-19 70.1 0.1 2.3e-15 56.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU82347.2 - 2.3e-12 47.2 0.0 7e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU82347.2 - 2.2e-05 24.2 0.0 0.00058 19.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family GPI2 PF06432.6 EAU82347.2 - 0.032 13.5 0.2 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase LPAM_1 PF08139.7 EAU82347.2 - 0.19 11.9 3.6 0.5 10.6 2.5 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site UPRTase PF14681.1 EAU82349.2 - 4e-60 202.5 0.0 2.1e-59 200.2 0.0 1.8 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Abhydrolase_4 PF08386.5 EAU82350.1 - 1.5e-22 79.3 0.0 3.4e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EAU82350.1 - 8.4e-20 71.3 0.4 1.2e-16 61.0 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU82350.1 - 1.9e-13 50.8 3.4 1.7e-11 44.4 1.3 3.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU82350.1 - 2.3e-07 30.6 0.0 0.019 14.7 0.0 3.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU82351.2 - 4.1e-16 59.2 0.1 2.9e-15 56.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EAU82351.2 - 2.3e-15 56.3 0.0 5.8e-11 42.1 0.0 2.5 2 0 0 2 2 2 2 TAP-like protein Abhydrolase_6 PF12697.2 EAU82351.2 - 1.5e-08 34.8 0.3 1.1e-06 28.7 0.1 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Tcf25 PF04910.9 EAU82353.2 - 1.3e-59 201.9 0.1 3.3e-59 200.6 0.0 1.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Apt1 PF10351.4 EAU82353.2 - 3.4 6.4 7.7 6.8 5.4 5.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cohesin PF00963.13 EAU82354.1 - 0.082 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Cohesin domain TIP49 PF06068.8 EAU82356.1 - 1.6e-177 590.1 0.0 1.9e-177 589.9 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EAU82356.1 - 1.5e-10 41.3 0.0 1.4e-06 28.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAU82356.1 - 4.5e-09 35.6 0.6 2.4e-07 30.0 0.0 2.8 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EAU82356.1 - 1.7e-07 31.4 0.0 2.5e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EAU82356.1 - 1.1e-05 25.1 0.1 0.0064 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU82356.1 - 3.1e-05 24.1 0.1 0.064 13.3 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EAU82356.1 - 0.00036 20.2 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EAU82356.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAU82356.1 - 0.0015 18.5 0.1 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU82356.1 - 0.0047 16.7 0.0 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAU82356.1 - 0.007 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAU82356.1 - 0.007 15.4 0.1 0.017 14.2 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EAU82356.1 - 0.0093 15.8 0.0 5.9 6.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EAU82356.1 - 0.014 16.2 0.0 0.037 14.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EAU82356.1 - 0.015 14.4 0.1 0.075 12.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EAU82356.1 - 0.025 14.0 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 EAU82356.1 - 0.037 13.2 0.3 0.61 9.2 0.0 2.7 3 0 0 3 3 3 0 PhoH-like protein AAA_18 PF13238.1 EAU82356.1 - 0.057 13.7 0.1 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EAU82356.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.10 EAU82356.1 - 0.096 12.5 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EAU82356.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PNP_UDP_1 PF01048.15 EAU82357.1 - 2.6e-31 108.4 0.0 3.3e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Fungal_trans PF04082.13 EAU82358.2 - 8.8e-37 126.3 0.1 1.4e-36 125.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU82358.2 - 3.7e-07 29.9 9.2 6.4e-07 29.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haemadin PF09065.5 EAU82360.2 - 2.2 7.9 6.3 1.5 8.4 1.8 2.5 2 1 0 2 2 2 0 Haemadin PAT1 PF09770.4 EAU82361.2 - 4.3 5.4 31.2 0.38 8.9 18.6 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AAA_16 PF13191.1 EAU82363.2 - 2.4e-06 27.6 0.0 9.8e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EAU82363.2 - 2.2e-05 24.1 0.1 9.4e-05 22.1 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU82363.2 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAU82363.2 - 0.0026 17.8 0.0 0.0083 16.2 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EAU82363.2 - 0.0083 15.5 0.0 0.029 13.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EAU82363.2 - 0.022 13.7 0.4 0.068 12.1 0.0 1.8 1 1 0 2 2 2 0 KAP family P-loop domain Arch_ATPase PF01637.13 EAU82363.2 - 0.044 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EAU82363.2 - 0.14 12.3 0.0 0.49 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EAU82364.1 - 2.9e-14 52.8 0.0 6.4e-12 45.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82364.1 - 0.0017 17.4 0.0 0.0041 16.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 EAU82364.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA_16 PF13191.1 EAU82365.2 - 8.1e-05 22.6 0.0 0.00031 20.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EAU82365.2 - 0.0044 16.9 0.0 0.42 10.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAU82365.2 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase API5 PF05918.6 EAU82365.2 - 0.13 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Tnp_DNA_bind PF14706.1 EAU82365.2 - 0.14 11.8 0.7 0.39 10.4 0.5 1.8 1 0 0 1 1 1 0 Transposase DNA-binding Pkinase PF00069.20 EAU82366.1 - 2.7e-14 52.9 0.0 2.3e-12 46.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82366.1 - 3.5e-06 26.2 0.1 1.5e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase CCDC142 PF14923.1 EAU82369.2 - 0.22 9.7 1.3 0.32 9.2 0.9 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 Abhydrolase_6 PF12697.2 EAU82371.1 - 9.9e-24 84.4 0.7 1.2e-23 84.2 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU82371.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU82371.1 - 0.0094 15.5 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold LysM PF01476.15 EAU82372.2 - 3.2e-16 58.9 0.2 1.4e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 LysM domain DUF3760 PF12586.3 EAU82373.2 - 0.0019 18.0 2.6 0.4 10.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3760) F-box-like PF12937.2 EAU82373.2 - 0.0023 17.6 0.2 0.0048 16.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU82373.2 - 0.0099 15.5 0.3 0.03 13.9 0.1 1.9 2 0 0 2 2 2 1 F-box domain LysM PF01476.15 EAU82374.2 - 3e-20 71.8 0.2 2e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain GF_recep_IV PF14843.1 EAU82374.2 - 0.1 12.2 0.8 0.13 11.9 0.5 1.1 1 0 0 1 1 1 0 Growth factor receptor domain IV Npa1 PF11707.3 EAU82375.1 - 5.4e-53 180.1 0.0 1.9e-52 178.3 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EAU82375.1 - 0.0032 17.6 0.9 0.023 14.8 0.0 3.0 4 0 0 4 4 4 1 Creb binding CDC45 PF02724.9 EAU82375.1 - 0.17 9.8 5.7 0.28 9.1 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 EAU82375.1 - 6.3 5.8 13.4 16 4.4 9.3 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EAU82375.1 - 9.1 4.6 12.2 19 3.5 8.4 1.4 1 0 0 1 1 1 0 Daxx Family Fungal_trans PF04082.13 EAU82376.2 - 3.1e-28 98.3 0.2 6e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU82376.2 - 0.0014 18.4 6.1 0.0028 17.5 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myosin_tail_1 PF01576.14 EAU82377.2 - 0.0014 16.4 4.1 0.0014 16.4 2.9 2.0 1 1 1 2 2 2 2 Myosin tail DUF1875 PF08961.5 EAU82377.2 - 0.0034 16.7 0.0 0.0034 16.7 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1875) Tropomyosin_1 PF12718.2 EAU82377.2 - 5.5 6.8 11.2 12 5.7 0.8 2.4 2 0 0 2 2 2 0 Tropomyosin like ADIP PF11559.3 EAU82377.2 - 6.4 6.6 14.5 0.022 14.6 3.5 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding NUDIX PF00293.23 EAU82378.2 - 3.7e-18 65.4 0.0 1.2e-16 60.5 0.0 2.5 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EAU82378.2 - 0.015 14.6 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain OTT_1508_deam PF14441.1 EAU82381.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase CLIP PF12032.3 EAU82382.1 - 0.7 10.0 9.2 3.8 7.6 0.6 2.6 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases F-box-like PF12937.2 EAU82383.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU82383.1 - 0.016 14.8 0.0 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 F-box domain WGG PF10273.4 EAU82384.1 - 1.2e-27 95.8 0.0 2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 CBFD_NFYB_HMF PF00808.18 EAU82385.2 - 1.8e-14 53.5 0.9 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAU82385.2 - 1.1e-05 25.4 0.1 2.3e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EAU82385.2 - 0.068 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X CLIP PF12032.3 EAU82386.2 - 0.5 10.5 8.9 3 8.0 0.5 2.6 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases F-box-like PF12937.2 EAU82387.2 - 0.00068 19.3 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU82387.2 - 0.036 13.7 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain RTA1 PF04479.8 EAU82388.1 - 4.8e-37 127.6 0.3 7.9e-37 126.9 0.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Glyco_hydro_92 PF07971.7 EAU82390.2 - 2.1e-127 425.8 0.3 3.3e-127 425.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 F-box-like PF12937.2 EAU82391.1 - 0.015 14.9 1.1 0.068 12.8 0.1 2.5 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 EAU82397.2 - 0.0081 15.8 0.0 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU82397.2 - 0.035 13.7 1.8 0.085 12.5 0.0 2.5 2 0 0 2 2 2 0 F-box domain RTP801_C PF07809.6 EAU82397.2 - 0.057 13.0 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 RTP801 C-terminal region DUF3557 PF12078.3 EAU82397.2 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) RTA1 PF04479.8 EAU82398.1 - 1.2e-38 132.8 1.1 1.9e-38 132.1 0.8 1.3 1 0 0 1 1 1 1 RTA1 like protein F-box-like PF12937.2 EAU82399.2 - 0.0031 17.2 0.2 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like Peroxidase_2 PF01328.12 EAU82400.2 - 3.7e-06 25.8 0.0 8e-06 24.7 0.0 1.6 1 1 0 1 1 1 1 Peroxidase, family 2 MIT PF04212.13 EAU82401.2 - 0.01 15.6 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF4398 PF14346.1 EAU82401.2 - 0.069 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Suf PF05843.9 EAU82402.2 - 4.9e-76 256.1 0.0 8.6e-73 245.4 0.0 4.1 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EAU82402.2 - 9.6e-09 35.1 5.4 0.065 13.8 0.0 7.5 5 3 4 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU82402.2 - 4.3e-07 30.1 0.3 4.2 7.7 0.0 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU82402.2 - 3e-06 27.7 3.6 0.071 13.8 0.0 4.4 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EAU82402.2 - 6.2e-05 22.1 6.2 0.87 8.5 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAU82402.2 - 0.019 14.6 1.4 0.48 10.1 0.0 3.3 3 1 0 3 3 3 0 TPR repeat FTCD_C PF04961.7 EAU82402.2 - 0.044 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase CRAL_TRIO_N PF03765.10 EAU82402.2 - 0.077 13.1 0.6 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain Mad3_BUB1_I PF08311.7 EAU82402.2 - 0.46 10.2 7.6 3.3 7.5 0.1 4.0 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 RP-C_C PF11800.3 EAU82402.2 - 1.6 8.3 5.3 2.5 7.7 2.4 2.1 1 1 1 2 2 2 0 Replication protein C C-terminal region RELT PF12606.3 EAU82403.1 - 0.18 10.9 1.4 0.42 9.8 0.9 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 TraX PF05857.6 EAU82403.1 - 0.2 11.2 5.8 0.36 10.4 4.0 1.3 1 0 0 1 1 1 0 TraX protein DUF1129 PF06570.6 EAU82403.1 - 3.2 7.0 5.8 6.2 6.0 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Rsa3 PF14615.1 EAU82404.1 - 2.9e-11 42.4 0.0 4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF2146 PF10220.4 EAU82404.1 - 0.11 10.4 9.6 0.11 10.4 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Macoilin PF09726.4 EAU82404.1 - 0.11 10.7 14.5 0.14 10.4 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 EAU82404.1 - 0.74 8.3 5.8 0.81 8.2 4.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.6 EAU82404.1 - 0.85 7.8 11.2 0.84 7.8 7.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Cwf_Cwc_15 PF04889.7 EAU82404.1 - 1.2 8.7 14.3 2.5 7.7 9.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 EAU82404.1 - 1.5 7.1 24.5 1.8 6.8 17.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sec10 PF07393.6 EAU82404.1 - 1.9 6.5 7.3 2.4 6.2 5.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 Sporozoite_P67 PF05642.6 EAU82404.1 - 2.7 5.7 19.9 3.5 5.3 13.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Totivirus_coat PF05518.6 EAU82404.1 - 3 5.5 8.0 3.7 5.2 5.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF605 PF04652.11 EAU82404.1 - 4.4 6.5 26.8 5.4 6.3 18.6 1.2 1 0 0 1 1 1 0 Vta1 like Mem_trans PF03547.13 EAU82404.1 - 4.9 5.3 5.8 5.8 5.0 4.0 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF3484 PF11983.3 EAU82404.1 - 5.1 8.0 6.8 1.3 9.9 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) KIAA1328 PF15369.1 EAU82404.1 - 5.3 6.7 9.7 6.6 6.4 6.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 SR-25 PF10500.4 EAU82404.1 - 5.4 6.4 52.8 0.9 8.9 12.1 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 EAU82404.1 - 7.2 4.1 12.9 8.2 3.9 8.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF936 PF06075.7 EAU82404.1 - 9.7 4.9 21.6 11 4.7 15.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) AIRC PF00731.15 EAU82405.2 - 1.3e-64 216.0 2.6 2.7e-64 214.9 1.8 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EAU82405.2 - 2.9e-59 199.2 0.0 4.4e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EAU82405.2 - 1.6e-10 41.0 0.0 2.8e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EAU82405.2 - 0.00018 20.3 0.0 0.0044 15.8 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EAU82405.2 - 0.0025 17.1 0.0 0.005 16.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PrpR_N PF06506.6 EAU82405.2 - 0.013 14.9 0.5 0.17 11.2 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator CoA_binding_2 PF13380.1 EAU82405.2 - 0.015 15.4 3.3 3.1 7.9 0.1 4.0 3 2 2 5 5 5 0 CoA binding domain ATP-grasp_3 PF02655.9 EAU82405.2 - 0.046 13.5 0.0 0.15 11.9 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain TPR_11 PF13414.1 EAU82406.2 - 8.5e-09 34.9 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EAU82406.2 - 6e-06 25.6 0.4 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU82406.2 - 0.0012 18.5 0.3 0.0059 16.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 EAU82406.2 - 0.0057 16.4 0.5 0.012 15.4 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU82406.2 - 0.14 12.0 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAU82407.2 - 2.1e-14 52.8 1.4 2.1e-13 49.6 0.8 2.2 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EAU82407.2 - 3e-13 48.7 3.1 5.1e-05 22.6 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU82407.2 - 1.1e-12 46.7 3.5 0.00046 19.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAU82407.2 - 3.4e-07 30.0 2.8 0.00058 19.7 1.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU82407.2 - 0.00033 20.2 1.7 0.44 10.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU82407.2 - 0.0012 19.4 0.4 0.019 15.6 0.0 2.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU82407.2 - 0.018 14.8 0.3 31 4.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAU82407.2 - 0.062 13.9 0.1 16 6.4 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EAU82407.2 - 0.12 12.5 3.4 0.16 12.1 1.0 2.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EAU82408.2 - 8e-12 44.6 0.1 6e-10 38.6 0.0 2.4 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 EAU82408.2 - 1.6e-10 40.1 0.2 0.00033 20.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU82408.2 - 3.6e-09 35.8 0.3 0.025 14.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAU82408.2 - 1.9e-07 30.9 2.9 0.00058 19.7 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAU82408.2 - 1.7e-06 28.0 1.9 0.51 10.9 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU82408.2 - 3.2e-05 23.3 0.1 0.052 13.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU82408.2 - 0.0023 18.3 0.6 10 7.0 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU82408.2 - 0.0024 18.5 0.0 0.031 14.9 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU82408.2 - 0.0044 17.1 0.6 0.047 13.8 0.2 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EAU82408.2 - 0.026 14.8 0.2 1.4 9.2 0.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EAU82408.2 - 0.068 13.2 0.0 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.24 EAU82409.1 - 8.7e-48 161.8 0.0 2.4e-41 141.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU82409.1 - 2e-07 31.1 0.1 2.3e-06 27.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EAU82409.1 - 5.6e-06 25.8 0.0 5.1e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EAU82409.1 - 2e-05 24.5 0.0 7.5e-05 22.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAU82409.1 - 8.5e-05 22.7 0.4 0.0059 16.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EAU82409.1 - 0.00026 20.6 0.6 0.0051 16.5 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain Bromodomain PF00439.20 EAU82409.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.9 EAU82409.1 - 0.0024 17.5 0.0 0.012 15.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EAU82409.1 - 0.0052 17.6 0.0 0.035 14.9 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EAU82409.1 - 0.0053 16.6 1.1 0.019 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAU82409.1 - 0.019 14.3 0.3 0.12 11.8 0.0 2.4 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EAU82409.1 - 0.021 15.1 0.2 0.38 11.0 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EAU82409.1 - 0.034 14.0 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EAU82409.1 - 0.04 13.1 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EAU82409.1 - 0.047 12.8 0.0 0.12 11.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAU82409.1 - 0.059 13.6 0.0 0.059 13.6 0.0 2.7 3 0 0 3 3 1 0 AAA domain TIP49 PF06068.8 EAU82409.1 - 0.088 11.5 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activat PF00158.21 EAU82409.1 - 0.1 12.0 0.0 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EAU82409.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Exo_endo_phos PF03372.18 EAU82410.2 - 1.6e-22 80.6 0.2 3.8e-22 79.4 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.11 EAU82411.2 - 1.3e-12 47.1 27.8 1.5e-12 46.8 14.1 3.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EAU82411.2 - 6.2e-12 45.2 1.6 2.8e-11 43.1 1.1 2.1 1 1 0 1 1 1 1 Nodulin-like CcmD PF04995.9 EAU82411.2 - 0.0046 16.6 0.7 0.018 14.7 0.5 2.0 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Pec_lyase_C PF00544.14 EAU82412.2 - 6.7e-40 136.6 6.5 9.3e-40 136.2 4.5 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EAU82412.2 - 0.00027 20.7 20.1 0.0048 16.6 6.5 2.3 2 0 0 2 2 2 2 Right handed beta helix region VIT1 PF01988.14 EAU82412.2 - 0.071 12.5 6.1 0.14 11.6 4.3 1.4 1 0 0 1 1 1 0 VIT family RA PF00788.18 EAU82413.1 - 2.9e-13 50.1 0.0 1.6e-09 38.1 0.0 3.9 2 1 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EAU82413.1 - 3.3e-06 26.3 0.1 1.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EAU82413.1 - 0.00022 20.7 0.2 0.00066 19.2 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Med15 PF09606.5 EAU82413.1 - 0.98 7.5 68.3 1.8 6.7 47.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ank_2 PF12796.2 EAU82414.1 - 4.2e-47 158.4 13.9 3.4e-15 56.1 1.0 8.0 4 2 3 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAU82414.1 - 4.2e-36 120.9 8.7 0.00046 19.8 0.0 12.4 13 0 0 13 13 13 7 Ankyrin repeat Ank_3 PF13606.1 EAU82414.1 - 1.7e-34 114.3 3.7 0.00065 19.7 0.0 12.2 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.1 EAU82414.1 - 2.2e-33 114.0 8.5 2.6e-07 30.9 0.1 9.2 8 1 1 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU82414.1 - 1.6e-27 94.8 11.2 1.7e-06 28.1 0.3 11.7 9 3 3 12 12 12 6 Ankyrin repeats (many copies) DNA_binding_1 PF01035.15 EAU82415.2 - 2.2e-25 88.1 0.0 3.2e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Glyco_hydro_85 PF03644.8 EAU82416.1 - 2.5e-75 253.5 0.1 3.9e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Nop14 PF04147.7 EAU82417.2 - 0.00011 20.2 13.3 0.00016 19.7 9.2 1.2 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.5 EAU82417.2 - 0.018 14.1 15.8 0.023 13.7 10.9 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 EAU82417.2 - 0.021 13.2 12.8 0.027 12.8 8.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 EAU82417.2 - 0.032 13.5 15.3 0.044 13.0 10.6 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EAU82417.2 - 1.2 7.5 18.3 2 6.7 12.7 1.3 1 0 0 1 1 1 0 Daxx Family Menin PF05053.8 EAU82417.2 - 1.4 6.9 4.4 1.8 6.6 3.1 1.1 1 0 0 1 1 1 0 Menin SpoIIIAH PF12685.2 EAU82417.2 - 1.4 8.3 8.2 2.8 7.3 5.7 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Glypican PF01153.14 EAU82417.2 - 2.1 6.8 4.0 2.5 6.6 2.8 1.3 1 0 0 1 1 1 0 Glypican DUF2201_N PF13203.1 EAU82417.2 - 5.1 6.1 6.4 7.6 5.6 4.4 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain UbiA PF01040.13 EAU82418.2 - 3.5e-26 91.9 24.9 1.2e-25 90.1 17.5 1.6 1 1 1 2 2 2 2 UbiA prenyltransferase family PPR_2 PF13041.1 EAU82422.1 - 7.2e-49 163.5 2.5 1.7e-08 34.3 0.0 13.4 10 3 4 14 14 14 9 PPR repeat family PPR PF01535.15 EAU82422.1 - 4.6e-45 148.5 13.9 9.2e-05 22.1 0.0 16.1 17 0 0 17 17 17 9 PPR repeat PPR_3 PF13812.1 EAU82422.1 - 3.3e-41 136.1 7.2 0.0012 18.8 0.0 14.4 15 0 0 15 15 15 9 Pentatricopeptide repeat domain PPR_1 PF12854.2 EAU82422.1 - 1.7e-28 97.7 0.0 0.00034 20.0 0.0 11.2 11 0 0 11 11 11 7 PPR repeat TPR_14 PF13428.1 EAU82422.1 - 9e-14 50.7 3.1 0.072 13.7 0.0 10.5 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU82422.1 - 1.2e-07 32.1 2.5 1.4 9.6 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU82422.1 - 5.6e-06 25.7 0.1 6.8 6.7 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat ECSIT PF06239.6 EAU82422.1 - 0.084 11.7 0.0 2 7.2 0.0 3.0 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway ssDNA-exonuc_C PF10141.4 EAU82422.1 - 0.17 11.3 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain F-box-like PF12937.2 EAU82423.2 - 3.8e-06 26.5 0.3 1.4e-05 24.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.8 EAU82423.2 - 1.6 9.3 3.9 2.2 8.9 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.2 EAU82424.1 - 4.1e-08 32.8 0.3 9.5e-07 28.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.8 EAU82424.1 - 0.4 11.2 4.0 2 9.0 0.5 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat UbiA PF01040.13 EAU82425.2 - 1.9e-12 46.9 20.0 6e-08 32.2 5.3 2.4 1 1 1 2 2 2 2 UbiA prenyltransferase family DUF3635 PF12330.3 EAU82426.2 - 0.043 13.8 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3635) RFC1 PF08519.7 EAU82427.1 - 8.9e-51 171.7 0.0 3.5e-49 166.5 0.0 2.7 2 1 1 3 3 3 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EAU82427.1 - 5.3e-12 45.7 0.0 2e-11 43.8 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EAU82427.1 - 1.7e-09 37.9 0.0 3.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EAU82427.1 - 6.2e-05 21.8 0.1 0.00043 19.1 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EAU82427.1 - 0.0021 17.6 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU82427.1 - 0.0031 17.2 0.0 0.0078 15.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EAU82427.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU82427.1 - 0.022 14.7 0.2 0.06 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EAU82427.1 - 0.032 14.3 0.2 0.28 11.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 EAU82427.1 - 0.032 13.7 0.0 0.089 12.2 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NACHT PF05729.7 EAU82427.1 - 0.036 13.7 0.0 4.4 6.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 EAU82427.1 - 0.041 14.7 0.1 0.16 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EAU82427.1 - 0.077 12.7 0.5 0.28 10.8 0.1 2.1 3 0 0 3 3 3 0 NTPase RuvB_N PF05496.7 EAU82427.1 - 0.11 11.4 0.0 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Penaeidin PF05927.6 EAU82431.1 - 2 8.9 6.9 8.8 6.9 4.8 2.2 1 1 0 1 1 1 0 Penaeidin F-box-like PF12937.2 EAU82433.1 - 7.4e-07 28.8 0.0 2.6e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like Pheromone PF08015.6 EAU82434.2 - 5.8e-06 27.0 1.3 0.00032 21.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Dysbindin PF04440.11 EAU82435.1 - 0.067 12.9 1.2 0.17 11.6 0.4 1.9 2 0 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) F-box-like PF12937.2 EAU82436.2 - 3.8e-06 26.5 0.0 1.3e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAU82436.2 - 3.6 7.4 10.8 6.1 6.6 0.2 4.5 3 2 2 5 5 5 0 Leucine rich repeat CDC45 PF02724.9 EAU82437.1 - 0.018 13.1 0.3 0.02 12.9 0.2 1.2 1 0 0 1 1 1 0 CDC45-like protein OmpH PF03938.9 EAU82437.1 - 0.27 11.1 11.1 0.43 10.5 7.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BBS2_C PF14782.1 EAU82437.1 - 0.28 9.7 5.1 0.4 9.1 3.5 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal RAP1 PF07218.6 EAU82437.1 - 1.5 6.8 10.2 2.2 6.2 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NARP1 PF12569.3 EAU82437.1 - 3.3 6.3 19.5 4.6 5.8 13.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hex_IIIa PF02455.11 EAU82437.1 - 8.9 4.8 8.5 15 4.1 5.9 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MRI PF15325.1 EAU82439.2 - 0.16 12.9 9.3 0.32 11.9 4.3 2.1 1 1 1 2 2 2 0 Modulator of retrovirus infection Nucleo_P87 PF07267.6 EAU82439.2 - 1.8 7.1 4.9 2.1 6.9 3.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box-like PF12937.2 EAU82440.1 - 5.2e-05 22.8 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like Type_III_YscG PF09477.5 EAU82440.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) WD40 PF00400.27 EAU82442.1 - 1.1e-10 41.0 8.0 0.0022 17.8 0.1 5.2 4 1 0 4 4 4 3 WD domain, G-beta repeat EF-hand_1 PF00036.27 EAU82443.2 - 3.1e-27 91.7 9.6 4.5e-06 25.5 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAU82443.2 - 3.1e-25 88.0 1.6 3e-13 49.6 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAU82443.2 - 2.8e-20 70.3 5.9 3.7e-05 23.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAU82443.2 - 3.1e-20 70.5 10.8 5e-06 25.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EAU82443.2 - 6.1e-15 54.5 10.3 0.00011 21.7 0.7 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 EAU82443.2 - 1.7e-06 27.7 5.6 0.002 17.8 0.3 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EAU82443.2 - 1.7e-06 28.0 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EAU82443.2 - 0.0011 18.8 0.1 0.34 10.8 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain Anthrax-tox_M PF09156.5 EAU82443.2 - 0.038 13.1 0.4 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain VCBS PF13517.1 EAU82443.2 - 0.085 13.2 2.3 6.8 7.1 0.2 2.5 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EAU82443.2 - 0.41 10.4 2.8 5 6.9 0.0 2.7 3 0 0 3 3 3 0 FG-GAP repeat WD40 PF00400.27 EAU82444.1 - 4.8e-14 51.6 10.1 2.2e-08 33.6 0.8 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 EAU82444.1 - 8.8e-05 22.3 2.1 0.017 14.8 0.1 3.4 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAU82444.1 - 0.00062 17.7 0.0 0.043 11.6 0.0 2.2 1 1 0 2 2 2 2 IKI3 family Pex14_N PF04695.8 EAU82444.1 - 1.9 8.5 4.6 17 5.4 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MRI PF15325.1 EAU82445.1 - 0.21 12.5 8.8 0.33 11.9 4.8 1.9 1 1 1 2 2 2 0 Modulator of retrovirus infection Spore_III_AB PF09548.5 EAU82446.2 - 0.34 10.6 3.6 1.7 8.3 0.0 3.2 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) DUF342 PF03961.8 EAU82446.2 - 0.6 8.4 4.6 1.5 7.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2304 PF10066.4 EAU82447.2 - 0.017 14.9 0.4 0.028 14.2 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) UBA_3 PF09288.5 EAU82447.2 - 0.038 13.5 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain YoqO PF14037.1 EAU82447.2 - 0.046 13.8 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 YoqO-like protein Potyvirid-P3 PF13608.1 EAU82448.2 - 0.015 14.4 0.9 0.015 14.4 0.6 1.9 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein DnaG_DnaB_bind PF08278.6 EAU82448.2 - 0.036 14.2 1.0 0.11 12.7 0.7 1.9 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Carbpep_Y_N PF05388.6 EAU82448.2 - 0.076 13.1 3.3 0.27 11.3 0.3 2.5 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide DUF2130 PF09903.4 EAU82448.2 - 0.078 11.7 8.1 0.021 13.5 0.8 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) ING PF12998.2 EAU82448.2 - 0.084 13.1 0.7 0.084 13.1 0.5 2.4 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding E1-E2_ATPase PF00122.15 EAU82448.2 - 0.17 10.8 3.1 0.56 9.1 1.3 2.2 2 1 0 2 2 2 0 E1-E2 ATPase DUF4064 PF13273.1 EAU82448.2 - 0.26 11.4 3.3 0.63 10.1 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF972 PF06156.8 EAU82448.2 - 3.1 8.1 5.3 1 9.7 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) PRKCSH-like PF12999.2 EAU82449.1 - 1.2e-54 184.5 2.5 1.3e-54 184.4 0.7 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EAU82449.1 - 1e-22 80.2 1.0 1.6e-22 79.6 0.0 1.7 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EAU82449.1 - 1.5e-11 44.9 0.9 5.1e-11 43.2 0.6 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EAU82449.1 - 0.00077 19.3 15.9 0.015 15.2 0.8 2.5 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A Sec8_exocyst PF04048.9 EAU82449.1 - 0.045 13.3 0.4 0.045 13.3 0.3 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DivIC PF04977.10 EAU82449.1 - 0.071 12.6 9.1 0.036 13.5 1.6 2.7 2 0 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 EAU82449.1 - 0.12 12.0 6.6 3.4 7.3 1.3 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6 PF04111.7 EAU82449.1 - 0.2 10.6 10.8 0.5 9.3 4.7 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 PV-1 PF06637.6 EAU82449.1 - 0.21 10.1 4.6 0.52 8.8 3.2 1.7 1 0 0 1 1 1 0 PV-1 protein (PLVAP) ATG16 PF08614.6 EAU82449.1 - 0.21 11.3 15.2 0.51 10.1 4.2 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 EAU82449.1 - 0.22 9.3 2.9 0.38 8.5 2.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EAU82449.1 - 0.25 10.9 15.5 8.9 5.8 7.7 3.0 2 1 1 3 3 3 0 IncA protein TMPIT PF07851.8 EAU82449.1 - 0.65 9.0 3.6 1.3 8.0 2.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein PEP-utilisers_N PF05524.8 EAU82449.1 - 0.69 9.7 13.9 0.45 10.3 0.6 3.1 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4407 PF14362.1 EAU82449.1 - 0.72 8.7 7.1 3.1 6.6 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 EAU82449.1 - 1.3 8.6 13.4 1 8.9 5.5 2.3 2 0 0 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.3 EAU82449.1 - 2.1 8.2 19.5 0.072 12.8 5.0 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.1 EAU82449.1 - 2.2 8.7 13.6 10 6.6 0.2 3.4 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Bap31 PF05529.7 EAU82449.1 - 2.7 7.4 9.0 0.75 9.2 3.1 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Prefoldin_2 PF01920.15 EAU82449.1 - 5.8 6.7 13.1 0.22 11.2 2.1 2.8 3 0 0 3 3 2 0 Prefoldin subunit Ribosomal_S25 PF03297.10 EAU82450.2 - 8.9e-41 138.1 3.1 1e-40 137.9 2.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EAU82450.2 - 0.019 14.3 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FGGY_C PF02782.11 EAU82451.2 - 1.1e-26 93.7 0.8 4.7e-26 91.6 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EAU82451.2 - 2.2e-17 63.1 0.1 4.5e-15 55.6 0.0 3.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain UPF0075 PF03702.9 EAU82451.2 - 0.0003 19.8 0.0 0.00051 19.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) BcrAD_BadFG PF01869.15 EAU82451.2 - 0.055 12.7 1.6 0.12 11.6 0.2 2.1 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MBOAT PF03062.14 EAU82454.1 - 6.5e-50 170.0 5.1 1.1e-49 169.2 3.6 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Mito_carr PF00153.22 EAU82456.1 - 2.5e-59 197.0 6.1 6.8e-19 67.3 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein JmjC PF02373.17 EAU82457.2 - 1.2e-10 41.6 0.0 3.1e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EAU82457.2 - 4.7e-07 29.5 0.0 7.1e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain AalphaY_MDB PF04611.7 EAU82457.2 - 0.0067 16.3 0.9 0.1 12.4 0.2 2.7 2 0 0 2 2 2 1 Mating type protein A alpha Y mating type dependent binding region Prok-RING_2 PF14445.1 EAU82457.2 - 1.7 8.6 13.9 0.27 11.2 4.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Ribosomal_L18e PF00828.14 EAU82460.1 - 4.6e-24 85.2 0.1 4.6e-24 85.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 EAU82461.2 - 1.3e-14 53.5 0.0 1e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU82461.2 - 4.3e-13 49.0 0.0 1.8e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU82461.2 - 3.2e-12 46.1 0.0 4.9e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EAU82461.2 - 0.0032 17.2 15.5 0.0032 17.2 10.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1777) GN3L_Grn1 PF08701.6 EAU82462.2 - 3.2e-22 78.2 19.6 3.2e-22 78.2 13.6 3.0 3 0 0 3 3 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EAU82462.2 - 3.1e-14 52.9 0.3 8.1e-11 41.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.11 EAU82462.2 - 7.9e-07 28.3 0.2 1.9e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EAU82462.2 - 2.6e-06 26.7 0.0 5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EAU82462.2 - 5.8e-06 25.6 0.0 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EAU82462.2 - 9.6e-06 25.1 0.0 0.079 12.3 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EAU82462.2 - 0.00015 21.6 17.5 0.00082 19.2 0.2 4.4 4 2 1 5 5 4 2 Dynamin family Miro PF08477.8 EAU82462.2 - 0.00026 21.4 0.0 0.012 16.0 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein Septin PF00735.13 EAU82462.2 - 0.00067 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Septin Nop14 PF04147.7 EAU82462.2 - 0.0011 16.9 21.1 0.0011 16.9 14.6 2.2 2 0 0 2 2 2 1 Nop14-like family YL1 PF05764.8 EAU82462.2 - 0.0037 16.9 26.0 0.0037 16.9 18.0 3.3 2 1 1 3 3 1 1 YL1 nuclear protein IIGP PF05049.8 EAU82462.2 - 0.06 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) F-box-like PF12937.2 EAU82464.1 - 6.8e-08 32.1 0.8 1e-06 28.3 0.0 3.0 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EAU82464.1 - 0.036 13.7 4.5 7.5 6.3 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) ECR1_N PF14382.1 EAU82465.1 - 2.8e-16 58.5 0.1 5.1e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EAU82465.1 - 0.00078 19.3 0.0 0.031 14.2 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 PUF PF00806.14 EAU82466.1 - 5.7e-16 57.0 0.0 0.0051 16.2 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat Katanin_con80 PF13925.1 EAU82466.1 - 0.061 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 con80 domain of Katanin SCO1-SenC PF02630.9 EAU82467.1 - 5.5e-56 188.9 0.0 6.9e-56 188.5 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EAU82467.1 - 1.1e-05 25.1 0.0 3.2e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EAU82467.1 - 0.0018 18.3 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Ank_2 PF12796.2 EAU82468.2 - 1.4e-81 268.9 27.7 1.6e-16 60.3 0.3 6.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAU82468.2 - 4.3e-62 202.9 15.8 1.1e-08 34.4 0.1 12.4 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 EAU82468.2 - 1.2e-58 194.4 9.8 1.8e-10 41.0 0.1 8.7 4 2 6 11 11 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU82468.2 - 3.6e-51 166.0 3.2 4.6e-05 23.2 0.0 12.8 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 EAU82468.2 - 4.6e-43 144.2 11.8 5.4e-08 32.8 0.0 10.0 1 1 11 12 12 12 11 Ankyrin repeats (many copies) AAA_16 PF13191.1 EAU82468.2 - 2.6e-05 24.2 0.4 0.00012 22.1 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAU82468.2 - 0.001 19.2 0.0 0.0066 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAU82468.2 - 0.0023 16.8 0.0 0.0052 15.6 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EAU82468.2 - 0.012 15.2 0.1 0.075 12.6 0.0 2.4 2 1 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 EAU82468.2 - 0.018 14.0 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BRCA-2_helical PF09169.5 EAU82468.2 - 0.023 14.2 0.0 0.39 10.2 0.0 2.8 3 1 1 4 4 4 0 BRCA2, helical AAA PF00004.24 EAU82468.2 - 0.12 12.6 0.0 0.6 10.3 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) OpuAC PF04069.7 EAU82468.2 - 0.12 11.7 1.5 5 6.3 0.0 3.6 3 1 2 5 5 5 0 Substrate binding domain of ABC-type glycine betaine transport system Nitro_FeMo-Co PF02579.12 EAU82468.2 - 0.14 12.2 5.8 3.5 7.7 0.0 4.4 2 2 3 6 6 6 0 Dinitrogenase iron-molybdenum cofactor NAD_binding_10 PF13460.1 EAU82470.1 - 0.00036 20.6 0.0 0.0021 18.1 0.0 2.1 2 1 1 3 3 3 1 NADH(P)-binding adh_short PF00106.20 EAU82470.1 - 0.13 12.1 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EAU82471.1 - 5.9e-18 65.5 0.0 1.3e-17 64.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAU82471.1 - 0.00047 19.6 0.0 0.022 14.1 0.0 2.7 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EAU82471.1 - 0.0045 16.2 0.0 0.041 13.1 0.0 2.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EAU82471.1 - 0.005 16.7 0.1 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EAU82471.1 - 0.037 12.9 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 EAU82471.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 KR domain PTR2 PF00854.16 EAU82472.1 - 2.1e-42 145.2 5.8 2.5e-41 141.7 4.0 2.2 1 1 0 1 1 1 1 POT family CcmH PF03918.9 EAU82472.1 - 1.1 8.2 7.4 2.3 7.1 0.0 3.4 2 1 1 3 3 3 0 Cytochrome C biogenesis protein DUF4064 PF13273.1 EAU82472.1 - 4.7 7.3 13.1 0.11 12.6 1.3 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF4064) DUF2975 PF11188.3 EAU82473.2 - 0.026 14.2 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) F-box-like PF12937.2 EAU82477.1 - 0.00035 20.2 3.6 0.00035 20.2 2.5 2.4 3 0 0 3 3 3 1 F-box-like Abhydrolase_6 PF12697.2 EAU82478.2 - 9e-14 51.9 0.1 2.1e-13 50.6 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU82478.2 - 8.7e-13 48.3 0.0 5.9e-12 45.6 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU82478.2 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EAU82478.2 - 0.026 13.7 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S10 PF00450.17 EAU82478.2 - 0.034 13.3 0.0 0.055 12.6 0.0 1.3 2 0 0 2 2 2 0 Serine carboxypeptidase F-box-like PF12937.2 EAU82479.2 - 9.2e-06 25.2 0.1 2.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like Actin PF00022.14 EAU82481.1 - 3.7e-155 516.2 0.0 4.2e-155 516.0 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EAU82481.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) p450 PF00067.17 EAU82482.2 - 3.6e-70 236.7 0.2 3.3e-67 227.0 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 VWA_2 PF13519.1 EAU82483.1 - 1e-09 38.7 8.2 7.7e-09 35.8 5.7 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EAU82483.1 - 2.5e-07 29.6 26.2 0.00046 19.5 2.3 4.6 4 1 0 4 4 4 3 Ubiquitin interaction motif Ssl1 PF04056.9 EAU82483.1 - 1.2e-05 25.0 0.1 3e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Ssl1-like Hamartin PF04388.7 EAU82483.1 - 1.1 7.8 7.2 1.6 7.3 5.0 1.1 1 0 0 1 1 1 0 Hamartin protein NESP55 PF06390.7 EAU82483.1 - 2.2 7.5 15.3 3.9 6.7 10.6 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) MSP1_C PF07462.6 EAU82483.1 - 8.6 4.6 14.3 13 3.9 9.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CGI-121 PF08617.5 EAU82484.1 - 3e-42 144.0 0.9 3.4e-42 143.8 0.6 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Thioredoxin PF00085.15 EAU82485.2 - 9e-53 176.3 0.1 7.8e-27 93.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EAU82485.2 - 1.4e-12 47.8 0.0 2.5e-06 27.4 0.0 3.7 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EAU82485.2 - 5.4e-09 36.2 4.3 0.00058 20.0 0.1 4.5 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAU82485.2 - 9.6e-08 32.0 3.0 0.0013 18.8 0.0 5.0 3 2 2 5 5 5 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EAU82485.2 - 0.00065 19.6 0.2 0.042 13.8 0.0 3.0 3 0 0 3 3 2 1 Thioredoxin-like DUF2457 PF10446.4 EAU82485.2 - 0.0023 16.7 9.0 0.0023 16.7 6.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EAU82485.2 - 0.0031 17.1 3.3 0.0061 16.2 2.3 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region CDC45 PF02724.9 EAU82485.2 - 0.059 11.4 2.4 0.09 10.7 1.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin_3 PF13192.1 EAU82485.2 - 0.059 13.1 0.1 21 5.0 0.0 2.8 2 0 0 2 2 2 0 Thioredoxin domain RXT2_N PF08595.6 EAU82485.2 - 0.068 12.9 3.7 0.16 11.7 2.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Thioredoxin_9 PF14595.1 EAU82485.2 - 0.076 12.5 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin DinB PF05163.7 EAU82485.2 - 0.15 11.7 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 DinB family Nop14 PF04147.7 EAU82485.2 - 0.43 8.4 5.3 0.7 7.7 3.6 1.2 1 0 0 1 1 1 0 Nop14-like family Thioredoxin_4 PF13462.1 EAU82485.2 - 0.49 10.3 2.3 3.3 7.6 0.1 3.0 3 1 1 4 4 4 0 Thioredoxin TFIIF_alpha PF05793.7 EAU82485.2 - 1.2 7.4 10.3 2 6.6 7.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) NOA36 PF06524.7 EAU82485.2 - 5.5 6.1 10.3 11 5.2 7.2 1.4 1 0 0 1 1 1 0 NOA36 protein Penaeidin PF05927.6 EAU82489.1 - 0.083 13.4 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 Penaeidin EMG1 PF03587.9 EAU82492.2 - 3.7e-75 251.6 0.0 4.8e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase F-box-like PF12937.2 EAU82495.1 - 0.0048 16.6 0.2 0.0048 16.6 0.1 2.3 3 0 0 3 3 3 1 F-box-like Pex24p PF06398.6 EAU82496.2 - 1.7e-15 56.7 13.8 1.3e-11 43.9 9.6 3.1 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin M_domain PF12938.2 EAU82497.2 - 8 6.1 9.5 24 4.6 6.2 2.0 1 1 1 2 2 2 0 M domain of GW182 F-box-like PF12937.2 EAU82500.2 - 5.3e-07 29.2 0.1 5.3e-07 29.2 0.0 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EAU82500.2 - 0.00039 20.0 0.1 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 1 F-box domain LRR_2 PF07723.8 EAU82500.2 - 0.65 10.5 0.1 0.65 10.5 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat F-box-like PF12937.2 EAU82501.2 - 0.00029 20.5 0.1 0.0012 18.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAU82501.2 - 0.052 13.1 2.6 17 5.1 0.0 4.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EAU82501.2 - 0.12 12.1 0.6 2.3 7.9 0.0 3.1 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.1 EAU82501.2 - 0.71 9.6 12.0 2 8.2 0.1 5.2 5 2 0 6 6 6 0 Leucine rich repeat SNF2_N PF00176.18 EAU82504.2 - 7.7e-14 51.1 0.0 1.1e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU82504.2 - 8.5e-10 38.3 0.0 2.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ODR4-like PF14778.1 EAU82507.2 - 0.24 10.0 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like APH PF01636.18 EAU82508.2 - 0.022 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tubulin_3 PF14881.1 EAU82508.2 - 0.086 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Tubulin domain TMEM220 PF15071.1 EAU82509.2 - 0.22 12.0 0.1 0.22 12.0 0.1 2.6 3 1 1 4 4 4 0 Transmembrane family 220, helix DUF2975 PF11188.3 EAU82509.2 - 0.32 10.7 11.7 0.58 9.8 2.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2975) DUF2628 PF10947.3 EAU82510.2 - 0.85 9.4 6.6 1.1 9.0 4.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Peptidase_M36 PF02128.10 EAU82511.2 - 1e-114 383.2 4.6 1.3e-114 382.9 3.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EAU82511.2 - 0.014 14.8 0.1 0.041 13.3 0.1 1.8 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DUF1996 PF09362.5 EAU82513.2 - 5.7e-71 238.8 0.0 7.7e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU82513.2 - 3.7e-10 39.2 9.7 3.7e-10 39.2 6.7 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain zf-C2H2 PF00096.21 EAU82516.1 - 2.1e-08 34.0 12.3 0.00014 21.9 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU82516.1 - 8.9e-06 25.7 17.4 0.00089 19.4 3.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU82516.1 - 0.00064 19.8 12.7 0.17 12.3 2.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger RPAP2_Rtr1 PF04181.8 EAU82516.1 - 0.031 14.3 0.2 0.07 13.2 0.2 1.5 1 0 0 1 1 1 0 Rtr1/RPAP2 family Fer4_18 PF13746.1 EAU82516.1 - 0.18 12.2 3.3 6.5 7.2 2.3 2.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain zf-met PF12874.2 EAU82516.1 - 1.8 8.8 13.9 1.8 8.8 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF1996 PF09362.5 EAU82517.2 - 1.3e-68 231.2 0.0 1.6e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) MLTD_N PF06474.7 EAU82518.2 - 0.13 12.5 1.1 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 MltD lipid attachment motif DUF1996 PF09362.5 EAU82519.2 - 7.5e-41 140.3 0.5 1e-24 87.5 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) MARVEL PF01284.18 EAU82520.1 - 0.039 13.7 1.2 0.051 13.3 0.9 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2975 PF11188.3 EAU82520.1 - 0.31 10.7 3.5 0.4 10.3 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) Coatomer_WDAD PF04053.9 EAU82527.2 - 8.1e-59 199.5 0.1 7.8e-58 196.3 0.0 2.4 2 1 2 4 4 4 1 Coatomer WD associated region WD40 PF00400.27 EAU82527.2 - 2.9e-49 163.2 11.2 1.9e-11 43.3 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EAU82527.2 - 3.2e-06 26.8 0.0 3.2 7.5 0.0 5.0 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EAU82527.2 - 0.00081 17.6 0.5 0.73 7.8 0.2 3.8 2 1 0 2 2 2 1 Nucleoporin Nup120/160 WRKY PF03106.10 EAU82528.2 - 0.018 14.8 0.1 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 WRKY DNA -binding domain SPT6_acidic PF14632.1 EAU82528.2 - 0.021 14.9 7.9 0.036 14.2 5.5 1.3 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF2244 PF10003.4 EAU82532.2 - 2.2 7.6 7.5 5.5 6.3 0.6 2.8 2 1 1 3 3 3 0 Integral membrane protein (DUF2244) Chitin_synth_2 PF03142.10 EAU82533.2 - 3.3e-212 705.5 0.5 6.6e-174 579.1 0.0 2.1 1 1 1 2 2 2 2 Chitin synthase Myosin_head PF00063.16 EAU82533.2 - 2.3e-85 287.0 0.0 8.6e-79 265.3 0.0 3.1 3 0 0 3 3 3 3 Myosin head (motor domain) Glyco_tranf_2_3 PF13641.1 EAU82533.2 - 6.5e-19 68.6 0.0 1.3e-14 54.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EAU82533.2 - 3.2e-17 62.8 1.7 3.2e-17 62.8 1.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EAU82533.2 - 7.1e-14 51.3 1.1 1.7e-13 50.0 0.7 1.7 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 EAU82533.2 - 1.9e-13 49.9 0.0 1.5e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EAU82533.2 - 2.1e-08 34.0 0.0 2.4e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAU82533.2 - 5.4e-06 25.8 0.0 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 DUF3253 PF11625.3 EAU82533.2 - 0.074 12.9 0.0 0.3 10.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) MgtE PF01769.11 EAU82534.2 - 4.3 7.6 6.2 0.9 9.8 1.0 2.2 2 1 0 2 2 2 0 Divalent cation transporter DUF4051 PF13260.1 EAU82535.2 - 0.38 10.1 5.7 8 5.8 4.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4051) DLH PF01738.13 EAU82536.2 - 2.8e-14 52.9 0.0 3.6e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU82536.2 - 4.4e-05 23.2 0.1 8.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU82536.2 - 0.012 15.5 0.2 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Mucin PF01456.12 EAU82536.2 - 6.6 6.4 29.1 14 5.4 20.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Multi_Drug_Res PF00893.14 EAU82537.2 - 0.075 13.5 1.4 0.15 12.5 1.0 1.5 1 1 0 1 1 1 0 Small Multidrug Resistance protein Shisa PF13908.1 EAU82540.1 - 0.095 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EAU82540.1 - 0.11 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain XhlA PF10779.4 EAU82541.2 - 0.047 13.6 0.5 0.11 12.3 0.3 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Shugoshin_N PF07558.6 EAU82542.2 - 0.087 12.5 0.5 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Transposase_21 PF02992.9 EAU82543.2 - 1.1e-11 44.2 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EAU82543.2 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF737 PF05300.6 EAU82544.2 - 0.023 14.6 0.2 0.042 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Coat_F PF07875.7 EAU82544.2 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Coat F domain ABC_tran PF00005.22 EAU82547.2 - 2.7e-41 141.0 0.0 1.3e-20 74.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EAU82547.2 - 8.3e-21 73.6 4.7 8.3e-21 73.6 3.3 2.0 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EAU82547.2 - 6.3e-17 62.4 0.9 0.0023 17.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EAU82547.2 - 2.9e-07 29.9 0.9 0.018 14.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU82547.2 - 3e-07 30.9 7.1 0.016 15.5 0.0 3.8 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EAU82547.2 - 3e-07 29.8 0.7 0.25 10.5 0.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EAU82547.2 - 1.3e-06 28.5 0.0 0.01 15.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EAU82547.2 - 1.1e-05 25.9 0.0 0.18 12.2 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EAU82547.2 - 0.00012 21.8 0.1 0.65 9.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EAU82547.2 - 0.00018 22.3 0.0 0.65 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAU82547.2 - 0.00035 20.7 0.1 1.2 9.3 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EAU82547.2 - 0.00043 20.5 0.3 1.7 8.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EAU82547.2 - 0.0005 19.5 0.1 3 7.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EAU82547.2 - 0.0013 18.2 0.0 1.5 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EAU82547.2 - 0.0015 18.0 0.0 0.97 8.8 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.1 EAU82547.2 - 0.0031 16.6 8.4 2.5 7.0 0.0 4.5 5 0 0 5 5 5 1 AAA ATPase domain SbcCD_C PF13558.1 EAU82547.2 - 0.004 17.0 0.0 0.67 9.9 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 EAU82547.2 - 0.0053 16.5 2.6 0.87 9.3 0.0 3.5 2 1 1 3 3 3 1 Dynamin family AAA_28 PF13521.1 EAU82547.2 - 0.0055 16.6 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAU82547.2 - 0.0063 15.7 0.1 0.39 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EAU82547.2 - 0.0085 16.0 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EAU82547.2 - 0.0094 15.8 0.0 8.9 6.2 0.0 3.9 5 0 0 5 5 3 0 AAA domain AAA_30 PF13604.1 EAU82547.2 - 0.012 15.2 0.0 0.62 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EAU82547.2 - 0.013 15.0 0.9 8.1 5.8 0.0 3.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EAU82547.2 - 0.014 15.5 2.3 8.1 6.6 0.0 3.2 3 0 0 3 3 3 0 RNA helicase DAP3 PF10236.4 EAU82547.2 - 0.036 13.0 2.6 9.6 5.0 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF87 PF01935.12 EAU82547.2 - 0.039 13.7 7.4 1.3 8.7 0.1 3.5 3 1 1 4 4 3 0 Domain of unknown function DUF87 MobB PF03205.9 EAU82547.2 - 0.041 13.5 0.8 7.8 6.1 0.0 2.9 2 1 1 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EAU82547.2 - 0.049 13.3 0.0 0.66 9.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EAU82547.2 - 0.056 13.3 0.0 14 5.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 EAU82547.2 - 0.099 12.8 0.0 21 5.3 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAU82547.2 - 0.13 11.9 0.0 15 5.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EAU82547.2 - 0.18 11.4 0.1 6.2 6.4 0.1 2.4 2 0 0 2 2 2 0 NTPase Pox_A32 PF04665.7 EAU82547.2 - 0.34 10.1 7.1 11 5.2 0.0 3.2 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_13 PF13166.1 EAU82547.2 - 0.64 8.4 5.4 5.6 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain PAP1 PF08601.5 EAU82548.2 - 6.5 6.3 6.7 8.7 5.9 4.6 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 F-box PF00646.28 EAU82549.1 - 0.00014 21.3 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU82549.1 - 0.0011 18.6 0.2 0.0024 17.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EAU82550.1 - 0.049 12.7 0.0 0.56 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain zf-MYND PF01753.13 EAU82551.2 - 1.4e-08 34.4 8.9 1.4e-08 34.4 6.2 2.1 2 0 0 2 2 2 1 MYND finger DUF825 PF05695.7 EAU82551.2 - 0.005 14.3 0.0 0.0058 14.1 0.0 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF825) DUF2296 PF10058.4 EAU82556.1 - 6.2e-22 77.1 0.5 9.4e-22 76.5 0.4 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) zf-CHY PF05495.7 EAU82556.1 - 0.033 14.3 0.3 0.054 13.6 0.2 1.3 1 0 0 1 1 1 0 CHY zinc finger PgaD PF13994.1 EAU82556.1 - 0.084 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein OPA3 PF07047.7 EAU82556.1 - 0.098 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Zn_Tnp_IS1595 PF12760.2 EAU82556.1 - 0.37 10.6 2.0 1.1 9.0 1.5 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EAU82556.1 - 1.4 8.7 4.4 5.9 6.7 2.7 2.0 1 1 1 2 2 2 0 PhnA Zinc-Ribbon AAA_17 PF13207.1 EAU82558.2 - 1.2e-06 29.3 0.0 1.5e-06 29.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EAU82558.2 - 0.058 13.2 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate kinase Herpes_gE PF02480.11 EAU82559.2 - 0.034 12.4 0.0 0.053 11.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 EAU82559.2 - 0.034 13.4 0.9 0.077 12.3 0.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4536 PF15055.1 EAU82559.2 - 0.063 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) Adeno_E3_CR2 PF02439.10 EAU82559.2 - 0.081 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EAU82560.1 - 0.00028 20.1 0.3 0.00051 19.2 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF347 PF03988.7 EAU82560.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF1049 PF06305.6 EAU82560.1 - 0.014 14.8 1.3 0.027 13.9 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4381 PF14316.1 EAU82560.1 - 0.16 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Phytase PF02333.10 EAU82560.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Phytase DUF1180 PF06679.7 EAU82560.1 - 3.5 7.4 12.5 4.6 7.1 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) RicinB_lectin_2 PF14200.1 EAU82561.2 - 8.8e-07 29.2 0.9 3.1e-06 27.4 0.6 1.8 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU82561.2 - 1.2e-05 25.2 4.5 3.5e-05 23.8 2.4 2.1 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Ricin_B_lectin PF00652.17 EAU82562.1 - 3.6e-16 59.3 3.4 5.6e-15 55.4 2.0 2.5 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU82562.1 - 2e-11 44.1 0.4 1.2e-07 32.0 0.1 2.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 EAU82562.1 - 0.00021 20.6 0.4 0.058 12.7 0.1 2.9 1 1 1 2 2 2 2 Cytolethal distending toxin A/C family DUF1399 PF07173.7 EAU82563.2 - 3.7e-24 85.5 0.4 5.7e-19 68.7 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF1399) Circo_capsid PF02443.10 EAU82567.2 - 0.16 11.2 0.1 16 4.7 0.0 2.1 2 0 0 2 2 2 0 Circovirus capsid protein DUF996 PF06195.8 EAU82568.2 - 0.057 13.4 4.4 0.068 13.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DLH PF01738.13 EAU82569.1 - 1.7e-07 30.7 0.0 2.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU82569.1 - 0.0079 15.9 0.1 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU82569.1 - 0.01 15.7 0.6 0.015 15.2 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 EAU82570.2 - 8.5e-05 21.8 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU82570.2 - 0.0058 16.4 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAU82571.2 - 0.00042 19.5 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU82571.2 - 0.0018 18.0 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short_C2 PF13561.1 EAU82572.1 - 1.6e-29 103.3 0.0 2.1e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU82572.1 - 6.5e-18 65.2 0.4 9.2e-18 64.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EAU82572.1 - 0.0025 17.0 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EAU82572.1 - 0.0054 16.4 0.5 0.0099 15.5 0.4 1.4 1 1 0 1 1 1 1 KR domain Alk_phosphatase PF00245.15 EAU82572.1 - 0.073 11.7 0.4 0.1 11.3 0.3 1.1 1 0 0 1 1 1 0 Alkaline phosphatase VWA_2 PF13519.1 EAU82572.1 - 0.13 12.4 0.0 4 7.5 0.0 2.2 1 1 0 2 2 2 0 von Willebrand factor type A domain F-box-like PF12937.2 EAU82573.1 - 1.2e-12 47.3 0.0 2.7e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU82573.1 - 0.00015 21.2 0.0 0.00044 19.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain TMEM61 PF15105.1 EAU82576.1 - 0.009 15.5 0.8 0.11 12.0 0.0 2.6 2 1 0 2 2 2 1 TMEM61 protein family IncA PF04156.9 EAU82576.1 - 0.17 11.4 1.3 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 IncA protein Ricin_B_lectin PF00652.17 EAU82577.2 - 2e-11 44.0 3.3 2.9e-07 30.5 0.2 2.7 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU82577.2 - 4.5e-11 43.0 1.4 3.7e-06 27.2 0.0 2.5 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like TraE PF05309.6 EAU82579.2 - 0.093 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 TraE protein Sugar_tr PF00083.19 EAU82583.1 - 1.2e-78 264.7 30.6 1.4e-78 264.5 21.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU82583.1 - 8.8e-28 97.0 38.4 9.4e-25 87.0 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EAU82583.1 - 0.00035 18.9 5.5 0.00064 18.0 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EAU82583.1 - 0.0031 15.9 13.1 0.0031 15.9 9.0 3.2 1 1 2 3 3 3 1 MFS/sugar transport protein ubiquitin PF00240.18 EAU82584.2 - 1.9e-23 81.6 0.1 2.1e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAU82584.2 - 9.5e-15 54.0 0.4 1e-14 53.9 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAU82584.2 - 0.00012 22.2 0.0 0.00029 21.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain MetJ PF01340.15 EAU82585.2 - 0.15 11.7 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Met Apo-repressor, MetJ His_Phos_2 PF00328.17 EAU82589.2 - 6.1e-37 127.7 0.0 8.4e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SPT6_acidic PF14632.1 EAU82589.2 - 0.0049 17.0 3.1 0.0086 16.2 2.1 1.3 1 0 0 1 1 1 1 Acidic N-terminal SPT6 Sema PF01403.14 EAU82589.2 - 0.091 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Sema domain AMP-binding PF00501.23 EAU82590.1 - 4.2e-86 288.9 0.0 5.4e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU82590.1 - 1.6e-05 25.7 0.0 3.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Phage_int_SAM_2 PF12834.2 EAU82593.1 - 0.13 12.6 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal Semialdhyde_dhC PF02774.13 EAU82596.1 - 4.1e-37 127.8 0.0 5.8e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EAU82596.1 - 1e-28 100.0 0.0 1.8e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Rab5ip PF07019.7 EAU82597.2 - 4e-13 49.3 2.1 4.9e-13 49.0 1.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_11 PF13414.1 EAU82600.1 - 4.5e-15 55.0 1.1 4.2e-08 32.7 0.0 5.2 5 1 1 6 6 6 2 TPR repeat TPR_12 PF13424.1 EAU82600.1 - 1.6e-09 37.5 0.0 0.0055 16.6 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU82600.1 - 1.6e-09 36.9 4.3 0.0007 19.3 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU82600.1 - 3.4e-09 35.8 0.0 0.00068 19.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU82600.1 - 1.7e-06 28.1 7.0 0.038 14.6 0.0 6.7 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU82600.1 - 3.4e-06 26.4 2.9 0.061 13.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAU82600.1 - 5.9e-05 22.9 0.0 0.9 9.8 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU82600.1 - 0.00013 22.5 6.4 0.0079 16.8 0.0 5.2 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAU82600.1 - 0.00056 19.7 1.0 0.056 13.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU82600.1 - 0.004 16.8 0.1 1.6 8.6 0.0 4.1 4 1 1 5 5 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EAU82600.1 - 0.0045 16.3 0.1 0.37 10.1 0.0 3.4 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 EAU82600.1 - 0.0052 17.0 0.2 0.32 11.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAU82600.1 - 0.0087 15.9 2.0 0.29 11.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAU82600.1 - 0.63 10.6 3.1 32 5.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat UAF_Rrn10 PF05234.6 EAU82602.2 - 0.00084 19.3 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 UAF complex subunit Rrn10 Plasmodium_Vir PF05795.6 EAU82602.2 - 0.71 9.0 4.7 0.082 12.0 0.2 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein BLVR PF06375.6 EAU82602.2 - 6.7 6.5 12.9 0.034 13.9 2.0 2.3 2 1 1 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Sec3_C PF09763.4 EAU82602.2 - 7.2 4.5 7.6 0.44 8.6 1.7 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec3 DDHD PF02862.12 EAU82602.2 - 9.2 5.9 10.1 0.42 10.3 1.4 2.2 2 0 0 2 2 2 0 DDHD domain Ribosomal_L13 PF00572.13 EAU82603.1 - 3.8e-46 156.3 0.1 5e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 zf-CCCH PF00642.19 EAU82604.2 - 0.0016 18.1 1.2 0.0029 17.2 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 EAU82605.1 - 1.6e-61 207.7 0.0 2.1e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82605.1 - 1.5e-30 106.1 0.0 3.4e-30 104.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU82605.1 - 0.00043 19.3 0.0 0.0007 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like F-box-like PF12937.2 EAU82606.2 - 7e-13 48.0 0.3 1.6e-11 43.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU82607.2 - 8.9e-11 41.3 0.4 1.9e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAU82607.2 - 0.0047 16.6 7.5 0.023 14.4 0.1 3.7 3 1 1 4 4 4 3 Leucine rich repeat F-box PF00646.28 EAU82607.2 - 0.68 9.6 3.9 2.3 7.9 0.2 3.1 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EAU82608.1 - 8e-10 38.2 0.7 1.6e-09 37.3 0.5 1.5 1 0 0 1 1 1 1 F-box-like DUF3375 PF11855.3 EAU82608.1 - 0.051 12.3 0.4 0.098 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) MerR-DNA-bind PF09278.6 EAU82608.1 - 0.053 13.9 0.3 0.16 12.4 0.2 1.9 1 0 0 1 1 1 0 MerR, DNA binding DUF1192 PF06698.6 EAU82608.1 - 0.098 12.4 0.3 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) LRR_4 PF12799.2 EAU82609.1 - 0.04 13.5 5.2 1.5 8.5 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Polysacc_synt_4 PF04669.8 EAU82609.1 - 0.059 12.7 0.1 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis FeS PF04060.8 EAU82609.1 - 1 8.9 4.5 2 8.0 3.1 1.4 1 0 0 1 1 1 0 Putative Fe-S cluster F-box-like PF12937.2 EAU82610.2 - 2.5e-07 30.2 2.7 6.2e-07 29.0 1.9 1.7 1 0 0 1 1 1 1 F-box-like DivIC PF04977.10 EAU82610.2 - 0.0051 16.2 1.8 0.0095 15.4 1.3 1.3 1 0 0 1 1 1 1 Septum formation initiator WD40_alt PF14077.1 EAU82610.2 - 0.06 12.9 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif MerR-DNA-bind PF09278.6 EAU82610.2 - 0.15 12.4 2.5 0.32 11.4 1.7 1.5 1 0 0 1 1 1 0 MerR, DNA binding DUF1843 PF08898.5 EAU82610.2 - 0.29 11.1 0.9 7.4 6.7 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) CASP_C PF08172.7 EAU82610.2 - 0.87 8.5 3.1 1.9 7.4 2.1 1.4 1 0 0 1 1 1 0 CASP C terminal NUDIX PF00293.23 EAU82611.1 - 7.2e-16 58.0 0.0 1.2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DSPc PF00782.15 EAU82612.2 - 1.2e-33 115.4 0.0 3.3e-31 107.6 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAU82612.2 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EAU82612.2 - 0.069 13.2 0.1 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EAU82612.2 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family p450 PF00067.17 EAU82615.2 - 1.5e-64 218.2 0.0 2.2e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.1 EAU82618.1 - 2e-17 63.1 0.1 4.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU82618.1 - 1.5e-11 44.1 0.0 3.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAU82618.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU82618.1 - 0.025 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BBP1_C PF15272.1 EAU82619.1 - 0.0005 19.6 8.6 0.0011 18.6 6.0 1.5 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal BTB PF00651.26 EAU82619.1 - 0.002 18.0 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Cast PF10174.4 EAU82619.1 - 0.0037 15.3 22.0 0.0037 15.3 15.2 1.3 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Peptidase_S64 PF08192.6 EAU82619.1 - 0.16 10.2 6.6 0.22 9.8 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Cortex-I_coil PF09304.5 EAU82619.1 - 0.27 11.2 15.9 0.11 12.5 8.0 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil APG6 PF04111.7 EAU82619.1 - 0.31 10.0 13.2 0.71 8.8 9.2 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EAU82619.1 - 0.61 9.2 20.0 0.99 8.5 13.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 EAU82619.1 - 1.7 6.9 6.5 2.6 6.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HAUS6_N PF14661.1 EAU82619.1 - 2.5 7.3 12.8 4.2 6.6 8.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4200 PF13863.1 EAU82619.1 - 2.7 7.9 29.3 1.2 9.0 5.7 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) FadA PF09403.5 EAU82619.1 - 3.3 7.7 13.2 6.8 6.7 9.1 1.5 1 0 0 1 1 1 0 Adhesion protein FadA ARD PF03079.9 EAU82619.1 - 3.5 7.5 7.9 0.98 9.3 2.9 1.9 1 1 0 1 1 1 0 ARD/ARD' family DUF4407 PF14362.1 EAU82619.1 - 5.7 5.8 9.7 11 4.8 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GST_N_3 PF13417.1 EAU82620.1 - 9.4e-13 48.1 0.0 3.3e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU82620.1 - 1.9e-09 37.3 0.0 7e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU82620.1 - 0.00017 21.3 0.1 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAU82620.1 - 0.00067 19.7 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU82620.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU82620.1 - 0.044 14.2 0.1 0.078 13.4 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAU82621.1 - 7.1e-12 45.3 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU82621.1 - 4.1e-11 42.7 0.1 1.5e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU82621.1 - 1.5e-07 31.1 0.5 3.2e-07 30.1 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU82621.1 - 1.3e-06 28.2 0.2 1.9e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU82621.1 - 0.00029 21.2 0.1 0.00057 20.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EAU82628.1 - 9.1e-09 34.9 0.8 2.5e-08 33.5 0.6 1.7 1 0 0 1 1 1 1 F-box-like DivIC PF04977.10 EAU82628.1 - 0.11 11.9 1.1 0.26 10.7 0.7 1.5 1 0 0 1 1 1 0 Septum formation initiator F-box-like PF12937.2 EAU82629.2 - 1.8e-15 56.3 0.5 1.8e-15 56.3 0.4 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAU82629.2 - 7.2e-05 22.3 0.2 6.2 6.5 0.0 5.1 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAU82629.2 - 0.91 9.9 3.4 52 4.6 0.3 4.3 5 0 0 5 5 5 0 Leucine rich repeat tRNA-synt_1g PF09334.6 EAU82630.2 - 6.7e-80 268.6 0.0 1.1e-79 267.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EAU82630.2 - 1.9e-12 45.9 0.2 1.2e-09 36.7 0.0 2.8 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EAU82630.2 - 2.2e-07 30.3 0.2 0.00023 20.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EAU82630.2 - 0.00041 20.1 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DUF4448 PF14610.1 EAU82631.1 - 0.0024 17.3 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2207 PF09972.4 EAU82632.2 - 0.0014 17.2 0.0 0.0021 16.7 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF1191 PF06697.7 EAU82632.2 - 0.0031 16.3 0.0 0.0056 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Rax2 PF12768.2 EAU82632.2 - 0.0036 16.5 0.0 0.0064 15.7 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF1180 PF06679.7 EAU82632.2 - 0.011 15.6 0.0 0.029 14.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Meckelin PF09773.4 EAU82632.2 - 0.17 9.6 0.0 0.23 9.1 0.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF2681 PF10883.3 EAU82632.2 - 0.36 11.0 0.1 0.36 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) F-box-like PF12937.2 EAU82633.1 - 0.091 12.5 0.9 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 EAU82638.2 - 1.3e-08 34.4 0.6 3.3e-08 33.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like DivIC PF04977.10 EAU82638.2 - 0.46 10.0 2.0 0.4 10.1 0.4 1.7 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.2 EAU82639.1 - 2.2e-11 43.2 0.5 5.6e-11 41.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like MerR-DNA-bind PF09278.6 EAU82639.1 - 0.019 15.3 0.8 0.056 13.8 0.6 1.8 1 0 0 1 1 1 0 MerR, DNA binding F-box-like PF12937.2 EAU82640.1 - 4.7e-10 39.0 0.8 4.7e-10 39.0 0.6 2.5 3 0 0 3 3 3 1 F-box-like HMG_box PF00505.14 EAU82642.2 - 0.0073 16.5 0.0 0.0073 16.5 0.0 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box DUF442 PF04273.8 EAU82643.2 - 0.16 11.8 0.7 4.5 7.1 0.0 2.9 3 2 0 3 3 3 0 Putative phosphatase (DUF442) GST_N_3 PF13417.1 EAU82645.1 - 7.3e-14 51.7 0.5 2.2e-13 50.1 0.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU82645.1 - 3.9e-11 42.7 0.0 9e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU82645.1 - 2.8e-06 27.1 0.0 6.2e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU82645.1 - 0.0042 17.5 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAU82646.1 - 2e-12 47.1 0.2 7.2e-12 45.3 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU82646.1 - 1.2e-08 34.7 0.0 3.6e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TMEM51 PF15345.1 EAU82647.2 - 7.1e-05 22.6 0.1 0.00012 21.8 0.1 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 Shisa PF13908.1 EAU82647.2 - 0.00089 19.4 0.4 0.0025 17.9 0.0 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator DUF2217 PF10265.4 EAU82647.2 - 0.0019 17.0 0.2 0.003 16.4 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) TMEM154 PF15102.1 EAU82647.2 - 0.0023 17.6 1.5 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.11 EAU82647.2 - 0.0025 16.1 0.1 0.004 15.4 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 EAU82647.2 - 0.015 14.9 0.0 0.048 13.2 0.0 1.8 1 0 0 1 1 1 0 Protocadherin DUF912 PF06024.7 EAU82647.2 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IncA PF04156.9 EAU82647.2 - 0.037 13.6 0.0 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 IncA protein Ctr PF04145.10 EAU82647.2 - 0.063 13.3 0.1 0.15 12.0 0.1 1.7 1 1 0 1 1 1 0 Ctr copper transporter family DUF4131 PF13567.1 EAU82647.2 - 0.092 12.1 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SKG6 PF08693.5 EAU82647.2 - 0.11 11.8 0.6 0.46 9.8 0.4 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD34_antigen PF06365.7 EAU82647.2 - 0.25 10.9 2.0 0.43 10.2 0.0 2.1 2 1 0 2 2 2 0 CD34/Podocalyxin family DUF1180 PF06679.7 EAU82647.2 - 0.42 10.4 0.0 0.42 10.4 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DUF3614 PF12267.3 EAU82647.2 - 0.49 10.6 0.0 0.49 10.6 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3614) DUF1515 PF07439.6 EAU82648.2 - 0.026 14.3 0.6 0.066 13.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Pex14_N PF04695.8 EAU82648.2 - 1.2 9.1 10.8 0.4 10.7 1.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PspA_IM30 PF04012.7 EAU82648.2 - 2.2 7.5 12.6 1.6 8.0 5.8 2.5 2 1 0 2 2 2 0 PspA/IM30 family Phage_GP20 PF06810.6 EAU82648.2 - 2.8 7.3 9.4 0.88 9.0 0.9 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF2730 PF10805.3 EAU82648.2 - 9.2 6.0 8.5 16 5.3 0.1 3.3 2 1 1 4 4 4 0 Protein of unknown function (DUF2730) DNA_ligase_OB_2 PF14743.1 EAU82651.2 - 5.2e-27 93.3 0.3 1.1e-26 92.3 0.2 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 EAU82651.2 - 4.4e-21 75.1 0.0 8.3e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain CcoS PF03597.10 EAU82652.1 - 0.44 10.0 3.6 0.88 9.0 2.5 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Cu_amine_oxid PF01179.15 EAU82653.2 - 7.7e-65 219.2 0.0 9.9e-31 106.8 0.0 3.1 2 1 1 3 3 3 3 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EAU82653.2 - 1.6e-10 40.7 0.4 4.6e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EAU82653.2 - 0.0001 22.3 0.0 0.0005 20.0 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.15 EAU82654.2 - 6.5e-92 308.3 0.1 9.6e-92 307.8 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain SAP18 PF06487.7 EAU82654.2 - 4.8e-24 84.4 0.0 9e-24 83.5 0.0 1.4 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF1965 PF09248.5 EAU82654.2 - 1e-08 34.9 0.0 2.8e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EAU82654.2 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Glyco_transf_52 PF07922.6 EAU82654.2 - 0.18 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 52 Arrestin_N PF00339.24 EAU82656.1 - 9e-05 22.3 0.2 0.00059 19.6 0.1 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Peptidase_M35 PF02102.10 EAU82657.2 - 2.1e-21 76.0 16.4 6.2e-21 74.4 11.4 1.7 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EAU82657.2 - 6.1e-06 26.8 0.8 1.2e-05 25.8 0.6 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EAU82657.2 - 6.7e-05 22.4 0.4 0.0001 21.7 0.3 1.3 1 0 0 1 1 1 1 Putative peptidase family CARDB PF07705.6 EAU82657.2 - 0.00066 19.6 0.2 0.003 17.5 0.0 2.2 2 0 0 2 2 2 1 CARDB Abhydrolase_6 PF12697.2 EAU82658.2 - 2e-30 106.3 0.1 2.8e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU82658.2 - 2.9e-17 62.7 0.0 4.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU82658.2 - 6.2e-16 58.6 0.0 1.7e-15 57.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAU82658.2 - 6.2e-07 29.1 0.0 2.2e-06 27.4 0.0 1.9 2 1 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EAU82658.2 - 7.4e-06 24.6 0.0 0.011 14.2 0.0 2.3 3 0 0 3 3 3 2 Ndr family Peptidase_S9 PF00326.16 EAU82658.2 - 0.00015 21.0 0.0 0.006 15.8 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EAU82658.2 - 0.0011 18.3 0.1 0.025 13.8 0.1 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EAU82658.2 - 0.002 17.8 0.0 0.78 9.4 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 EAU82658.2 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.7 EAU82658.2 - 0.028 12.9 0.0 0.059 11.9 0.0 1.6 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Ribosomal_L7Ae PF01248.21 EAU82659.1 - 2.1e-27 94.4 2.9 2.6e-27 94.1 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family WD40 PF00400.27 EAU82660.2 - 2.5e-27 93.7 25.2 6.6e-11 41.6 0.9 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3312 PF11768.3 EAU82660.2 - 0.00047 18.5 0.0 0.00092 17.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) IKI3 PF04762.7 EAU82660.2 - 0.0011 16.8 0.0 0.0017 16.2 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Nbas_N PF15492.1 EAU82660.2 - 0.0016 17.5 0.3 2.6 7.0 0.0 3.2 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal WW PF00397.21 EAU82661.1 - 0.003 17.3 0.4 0.0066 16.2 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF3095 PF11294.3 EAU82661.1 - 0.013 14.4 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) AT_hook PF02178.14 EAU82662.1 - 0.44 10.3 23.0 0.12 12.0 1.9 3.8 3 0 0 3 3 3 0 AT hook motif BRCT PF00533.21 EAU82663.1 - 7.6e-09 35.6 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EAU82663.1 - 3.4e-07 30.0 0.0 1.5e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 EAU82663.1 - 0.00029 20.9 0.1 0.00083 19.4 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EAU82663.1 - 0.0042 16.8 0.5 0.0077 15.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) F-box-like PF12937.2 EAU82664.1 - 3.7e-10 39.3 1.1 8.2e-10 38.2 0.8 1.6 1 0 0 1 1 1 1 F-box-like SMC_N PF02463.14 EAU82665.1 - 2.3e-21 76.0 0.1 3.4e-21 75.5 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAU82665.1 - 7.4e-11 42.7 23.8 7.4e-11 42.7 16.5 4.9 3 2 0 3 3 1 1 AAA domain AAA_21 PF13304.1 EAU82665.1 - 1.3e-06 28.6 0.6 9.9e-05 22.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 EAU82665.1 - 0.0014 17.8 1.3 6.2 5.9 0.0 3.7 3 1 1 4 4 4 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 EAU82665.1 - 0.0033 16.9 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.7 EAU82665.1 - 0.0061 16.3 11.9 1 9.1 0.1 5.9 6 1 1 7 7 7 1 Baculovirus polyhedron envelope protein, PEP, C terminus IstB_IS21 PF01695.12 EAU82665.1 - 0.0089 15.4 0.0 0.041 13.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AKNA PF12443.3 EAU82665.1 - 0.011 15.6 0.2 0.011 15.6 0.1 6.1 5 2 1 6 6 6 0 AT-hook-containing transcription factor EzrA PF06160.7 EAU82665.1 - 0.015 13.5 51.2 0.021 13.0 13.6 4.8 2 2 1 3 3 3 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 EAU82665.1 - 0.084 13.0 0.2 0.084 13.0 0.2 6.8 5 2 1 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA PF00004.24 EAU82665.1 - 0.38 10.9 0.0 0.38 10.9 0.0 3.6 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU82665.1 - 1 10.2 6.1 0.69 10.7 0.0 3.7 2 1 0 2 2 2 0 AAA domain DUF2937 PF11157.3 EAU82665.1 - 2.7 7.2 6.2 16 4.8 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2937) DUF3373 PF11853.3 EAU82665.1 - 9.6 4.6 12.6 4.5 5.6 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3373) RNase_PH PF01138.16 EAU82666.1 - 1.5e-09 38.2 0.0 4.3e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 SOG2 PF10428.4 EAU82667.1 - 1.1 7.9 17.3 1.4 7.4 12.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1777 PF08648.7 EAU82667.1 - 4.3 7.0 21.0 0.14 11.9 9.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) KIAA1328 PF15369.1 EAU82667.1 - 4.4 7.0 15.9 5.6 6.6 10.8 1.3 1 1 0 1 1 1 0 Uncharacterised protein KIAA1328 F-box-like PF12937.2 EAU82669.1 - 6.3e-08 32.2 4.4 6.2e-07 29.0 0.1 3.5 3 1 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EAU82669.1 - 0.13 11.9 12.5 1 9.0 0.0 5.0 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAU82669.1 - 7.3 7.0 10.5 1.6e+02 2.8 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich repeat TAF4 PF05236.9 EAU82670.2 - 3e-25 89.0 9.3 3e-25 89.0 6.5 2.9 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.20 EAU82671.2 - 1.7e-05 24.1 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAU82671.2 - 0.006 15.6 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU82671.2 - 0.017 14.8 0.4 3.7 7.2 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU82671.2 - 0.15 11.6 0.1 8.6 5.8 0.1 2.3 1 1 1 2 2 2 0 Choline/ethanolamine kinase F-box-like PF12937.2 EAU82672.1 - 8.6e-11 41.3 0.6 2.5e-10 39.9 0.4 1.9 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EAU82672.1 - 0.44 10.9 2.7 46 4.8 0.0 4.7 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 EAU82673.1 - 6.7e-10 38.5 0.9 2.4e-09 36.7 0.6 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU82673.1 - 0.011 15.2 2.9 3.7 7.2 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAU82673.1 - 0.54 10.6 3.8 37 5.1 0.1 5.2 6 0 0 6 6 6 0 Leucine rich repeat DUF1992 PF09350.5 EAU82674.2 - 7.5e-19 67.3 0.0 1.9e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) UCH PF00443.24 EAU82675.1 - 9.2e-35 120.0 0.0 1.2e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU82675.1 - 1.7e-12 47.4 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 EAU82676.2 - 2e-20 73.0 0.4 6.5e-13 48.4 0.1 3.7 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82676.2 - 0.00011 21.4 0.0 0.049 12.6 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Vps36_ESCRT-II PF11605.3 EAU82678.1 - 0.00018 21.2 0.0 0.00063 19.5 0.0 1.9 3 0 0 3 3 3 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EAU82678.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 GRAM domain p450 PF00067.17 EAU82679.2 - 2.7e-40 138.2 0.0 3.1e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EAU82680.2 - 3.8e-07 29.7 4.2 1.5e-06 27.8 2.9 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAU82680.2 - 0.00014 21.5 0.9 0.23 11.2 0.1 3.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 EAU82680.2 - 0.0024 17.4 0.9 2.6 7.7 0.0 4.4 3 2 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAU82680.2 - 0.014 15.4 7.7 6.7 7.3 0.5 4.6 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 EAU82680.2 - 0.024 14.5 2.9 8.1 6.9 0.1 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 EAU82680.2 - 0.043 13.8 2.4 18 5.8 0.1 4.1 3 1 0 3 3 3 0 Leucine Rich repeat F-box-like PF12937.2 EAU82681.1 - 8.3e-11 41.4 2.0 8.3e-11 41.4 1.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU82681.1 - 0.00039 20.0 4.0 0.0023 17.5 2.7 2.4 1 1 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EAU82681.1 - 0.04 13.6 6.2 6.5 6.5 0.5 3.7 2 1 2 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 EAU82681.1 - 0.38 11.1 7.7 12 6.5 0.1 5.6 6 1 1 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 EAU82681.1 - 1.7 8.3 9.0 62 3.3 0.1 4.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) RRP7 PF12923.2 EAU82682.1 - 1.4e-37 128.6 5.1 1.4e-37 128.6 3.6 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EAU82682.1 - 4.6e-05 22.9 0.0 0.00081 18.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU82682.1 - 0.0012 18.8 0.0 0.0082 16.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Peptidase_M35 PF02102.10 EAU82683.2 - 1.7e-14 53.2 4.6 1.8e-14 53.1 3.2 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 EAU82683.2 - 6.6e-07 28.9 0.4 9.2e-07 28.5 0.3 1.3 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 EAU82683.2 - 1.4e-05 25.5 0.6 2.2e-05 25.0 0.4 1.4 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Band_7 PF01145.20 EAU82684.1 - 8e-23 81.2 3.9 1.4e-22 80.5 2.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Piwi PF02171.12 EAU82685.2 - 5.8e-72 242.2 0.0 8.7e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EAU82685.2 - 2.2e-14 52.5 0.1 6.7e-14 50.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EAU82685.2 - 9.7e-06 24.9 0.0 1.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain 4HBT PF03061.17 EAU82686.2 - 3.6e-08 33.4 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DASH_Spc19 PF08287.6 EAU82687.1 - 3.1e-21 75.5 4.2 1e-19 70.6 2.8 2.1 1 1 0 1 1 1 1 Spc19 CASP_C PF08172.7 EAU82687.1 - 0.014 14.4 0.7 0.019 14.0 0.5 1.2 1 0 0 1 1 1 0 CASP C terminal Gp-FAR-1 PF05823.7 EAU82692.2 - 0.019 14.9 6.9 0.014 15.3 2.3 2.2 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) bZIP_1 PF00170.16 EAU82692.2 - 3.2 7.7 13.6 1.5 8.8 1.2 3.8 3 0 0 3 3 3 0 bZIP transcription factor RRM_1 PF00076.17 EAU82695.2 - 2.2e-33 113.7 0.0 2.5e-16 59.0 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU82695.2 - 6.5e-21 74.0 0.0 4.6e-11 42.5 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU82695.2 - 4.1e-14 52.1 0.1 9.6e-10 38.1 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU82695.2 - 2.1e-06 27.5 0.1 1.1e-05 25.1 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EAU82695.2 - 0.001 18.7 0.0 0.0039 16.9 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif F-box-like PF12937.2 EAU82696.2 - 4.4e-05 23.1 0.7 0.00011 21.8 0.5 1.7 1 0 0 1 1 1 1 F-box-like TSC22 PF01166.13 EAU82696.2 - 0.0079 16.1 0.1 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 TSC-22/dip/bun family IFP_35_N PF07334.8 EAU82696.2 - 0.16 11.9 0.1 0.5 10.3 0.1 1.8 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus F-box-like PF12937.2 EAU82697.1 - 0.016 14.9 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like IFP_35_N PF07334.8 EAU82697.1 - 0.095 12.6 1.0 0.2 11.6 0.7 1.4 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus F-box-like PF12937.2 EAU82701.2 - 7.8e-11 41.5 1.2 1.5e-10 40.6 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU82701.2 - 0.00088 18.8 0.2 0.0021 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU82702.1 - 2e-10 40.2 0.1 5e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF2723 PF11028.3 EAU82702.1 - 0.05 13.0 0.1 0.096 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Na_H_Exchanger PF00999.16 EAU82703.1 - 1.1e-61 208.4 48.2 1.7e-61 207.8 33.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G10 PF01125.12 EAU82704.1 - 1.1e-64 216.3 6.8 1.2e-64 216.2 4.7 1.0 1 0 0 1 1 1 1 G10 protein TB2_DP1_HVA22 PF03134.14 EAU82705.2 - 4.3e-11 42.4 0.0 8.2e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Lip_prot_lig_C PF10437.4 EAU82708.2 - 3.4e-06 26.6 0.0 6.1e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.14 EAU82709.1 - 0.00022 21.2 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CHCH PF06747.8 EAU82710.1 - 0.0025 17.6 3.6 0.0025 17.6 2.5 2.8 1 1 1 3 3 3 2 CHCH domain Pet191_N PF10203.4 EAU82710.1 - 0.34 10.9 12.9 2.4 8.2 7.6 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Defensin_1 PF00323.14 EAU82710.1 - 1.4 9.3 6.1 3.7 7.9 1.8 2.4 2 0 0 2 2 2 0 Mammalian defensin Cmc1 PF08583.5 EAU82710.1 - 6.4 6.6 15.9 7.1 6.4 4.7 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EAU82710.1 - 6.7 6.8 13.1 0.37 10.8 3.0 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF498 PF04430.9 EAU82712.1 - 1.8e-29 101.5 0.0 2.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Clathrin PF00637.15 EAU82714.2 - 9e-26 90.1 0.6 1.9e-25 89.0 0.4 1.5 1 0 0 1 1 1 1 Region in Clathrin and VPS WD40 PF00400.27 EAU82714.2 - 0.0091 15.8 0.1 0.12 12.2 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat Vps39_1 PF10366.4 EAU82714.2 - 0.013 15.4 1.4 0.37 10.8 0.0 3.1 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.1 EAU82714.2 - 0.3 10.9 2.6 6.8 6.6 0.2 2.5 2 0 0 2 2 2 0 Ring finger domain Alpha_kinase PF02816.13 EAU82716.1 - 2.3e-16 60.0 0.0 3.8e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family HypA PF01155.14 EAU82716.1 - 1.9 8.1 9.6 6.2 6.5 1.3 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EAU82716.1 - 8.6 6.2 8.9 21 5.0 6.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 EAU82716.1 - 9.7 6.1 9.5 1.9e+02 2.0 6.8 2.4 1 1 0 1 1 1 0 FYVE zinc finger DUF3375 PF11855.3 EAU82719.1 - 0.0073 15.0 0.0 0.0073 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) F-box-like PF12937.2 EAU82719.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.5 2 0 0 2 2 2 0 F-box-like DUF1192 PF06698.6 EAU82719.1 - 0.039 13.7 0.1 0.064 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MerR-DNA-bind PF09278.6 EAU82719.1 - 0.1 12.9 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 MerR, DNA binding DUF3435 PF11917.3 EAU82720.1 - 0.02 13.6 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) F-box-like PF12937.2 EAU82726.2 - 4.5e-13 48.7 1.0 9.4e-13 47.6 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU82726.2 - 0.11 12.2 4.4 0.22 11.2 0.3 3.1 2 1 0 2 2 2 0 F-box domain FAD_binding_4 PF01565.18 EAU82727.1 - 7.3e-29 100.0 3.9 7.3e-29 100.0 2.7 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAU82727.1 - 1.7e-08 34.2 0.1 3.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EAU82728.1 - 1.7e-31 108.5 3.3 4.7e-31 107.1 1.7 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAU82728.1 - 5.7e-07 29.3 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Hemocyanin_N PF03722.9 EAU82728.1 - 0.15 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain PH PF00169.24 EAU82730.2 - 5.9e-14 52.1 0.6 1.6e-13 50.7 0.0 2.1 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 EAU82730.2 - 1.8e-12 46.8 0.0 3.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EAU82730.2 - 1.7e-10 40.8 0.1 3.9e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EAU82730.2 - 3.2e-06 26.6 0.1 2.5e-05 23.7 0.1 2.4 1 1 0 1 1 1 1 Variant SH3 domain Ste50p-SAM PF09235.5 EAU82730.2 - 0.015 15.3 0.3 0.03 14.3 0.2 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SH3_1 PF00018.23 EAU82730.2 - 0.017 14.4 0.0 0.079 12.3 0.0 2.2 1 1 0 1 1 1 0 SH3 domain PH_11 PF15413.1 EAU82730.2 - 0.1 12.8 6.2 0.089 13.0 0.3 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain SAM_PNT PF02198.11 EAU82730.2 - 0.17 11.6 0.2 0.55 10.0 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF4470 PF14737.1 EAU82731.1 - 7.9e-21 73.6 0.0 1.7e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EAU82731.1 - 2.8e-10 39.8 13.4 5.9e-10 38.8 9.3 1.6 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 EAU82732.1 - 8.3e-08 31.8 2.4 3e-07 30.0 1.7 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU82734.2 - 3.6e-10 39.4 1.9 8.5e-10 38.2 1.3 1.7 1 0 0 1 1 1 1 F-box-like YL1 PF05764.8 EAU82734.2 - 0.077 12.5 3.1 0.071 12.7 0.7 1.9 2 0 0 2 2 2 0 YL1 nuclear protein F-box PF00646.28 EAU82734.2 - 0.11 12.2 2.0 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 F-box domain Meckelin PF09773.4 EAU82735.1 - 0.024 12.4 0.3 0.036 11.8 0.2 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) SLY PF12485.3 EAU82736.1 - 0.073 13.3 1.0 0.14 12.3 0.7 1.4 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein F-box-like PF12937.2 EAU82737.1 - 2.2e-09 36.8 0.6 4.9e-09 35.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EAU82738.1 - 1.4e-41 138.9 6.6 1.5e-08 34.1 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EAU82738.1 - 0.0025 16.1 0.0 0.045 12.0 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF3312 PF11768.3 EAU82738.1 - 0.22 9.6 0.0 1.1 7.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Cullin PF00888.17 EAU82739.1 - 1e-185 618.7 15.1 1.5e-185 618.1 10.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAU82739.1 - 3e-27 94.2 4.3 3e-27 94.2 3.0 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1727 PF08353.5 EAU82739.1 - 0.021 14.4 0.3 0.098 12.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1727) MarR_2 PF12802.2 EAU82739.1 - 0.023 14.3 0.1 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 MarR family Rrf2 PF02082.15 EAU82739.1 - 0.059 13.4 1.0 0.18 11.9 0.3 2.1 2 0 0 2 2 2 0 Transcriptional regulator Aldedh PF00171.17 EAU82741.1 - 7.2e-104 347.6 0.0 8.7e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.26 EAU82742.1 - 8.7e-11 41.8 0.0 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pro_isomerase PF00160.16 EAU82743.2 - 1.3e-39 135.8 0.0 1.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Neural_ProG_Cyt PF06567.6 EAU82743.2 - 0.038 14.1 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain DUF1777 PF08648.7 EAU82743.2 - 0.61 9.8 37.3 1.2 8.8 25.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4614 PF15391.1 EAU82743.2 - 4.8 6.9 9.2 7.8 6.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Nup188 PF10487.4 EAU82745.2 - 2.8e-16 58.6 0.1 2e-12 45.9 0.0 4.0 5 0 0 5 5 5 2 Nucleoporin subcomplex protein binding to Pom34 DUF3414 PF11894.3 EAU82745.2 - 0.00037 17.5 0.9 0.005 13.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3414) CSTF2_hinge PF14327.1 EAU82745.2 - 0.00087 19.3 1.5 13 5.9 0.0 4.3 3 0 0 3 3 3 2 Hinge domain of cleavage stimulation factor subunit 2 XPC-binding PF09280.6 EAU82745.2 - 0.0014 17.9 0.4 0.12 11.8 0.1 2.9 2 0 0 2 2 2 1 XPC-binding domain MMR_HSR1 PF01926.18 EAU82746.2 - 1.2e-09 38.0 0.2 3e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU82746.2 - 8.7e-09 34.7 0.0 8.7e-09 34.7 0.0 2.4 2 1 1 3 3 3 1 AIG1 family Dynamin_N PF00350.18 EAU82746.2 - 8.2e-06 25.7 5.0 0.00082 19.2 1.1 4.2 2 2 1 3 3 2 2 Dynamin family Septin PF00735.13 EAU82746.2 - 0.00022 20.3 0.0 0.00022 20.3 0.0 2.3 2 1 0 2 2 1 1 Septin DUF258 PF03193.11 EAU82746.2 - 0.00033 19.8 0.6 0.001 18.3 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GBP PF02263.14 EAU82746.2 - 0.0019 17.3 0.1 0.062 12.3 0.0 2.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain IIGP PF05049.8 EAU82746.2 - 0.0039 16.0 0.5 0.0039 16.0 0.3 2.2 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EAU82746.2 - 0.0067 16.9 0.4 0.15 12.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 EAU82746.2 - 0.0076 15.5 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 EAU82746.2 - 0.026 14.0 0.3 0.046 13.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EAU82746.2 - 0.038 13.5 0.4 1.1 8.6 0.4 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EAU82746.2 - 0.067 14.0 0.0 0.067 14.0 0.0 3.0 2 1 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EAU82746.2 - 0.074 12.5 0.2 0.074 12.5 0.1 3.1 3 1 0 3 3 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EAU82746.2 - 0.12 12.7 15.7 11 6.2 10.8 2.8 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 EAU82746.2 - 0.61 9.1 0.0 0.61 9.1 0.0 2.1 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region MIP-T3 PF10243.4 EAU82746.2 - 2.1 6.6 42.1 2.8 6.3 29.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ACR_tran PF00873.14 EAU82746.2 - 2.6 5.3 4.2 3.4 4.9 2.9 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Xan_ur_permease PF00860.15 EAU82748.2 - 3.9e-58 196.7 32.0 1.6e-56 191.4 22.2 2.1 1 1 0 1 1 1 1 Permease family Hist_deacetyl PF00850.14 EAU82749.2 - 4.5e-79 265.9 0.1 7e-79 265.3 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.20 EAU82750.2 - 1.1e-13 50.9 0.0 3.1e-12 46.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82750.2 - 9.3e-05 21.6 0.1 0.00061 18.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase 2OG-FeII_Oxy_2 PF13532.1 EAU82752.2 - 8.8e-11 41.9 0.0 1.2e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAU82752.2 - 0.0001 22.5 0.1 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 4HBT PF03061.17 EAU82753.1 - 1.2e-08 34.9 0.1 2.2e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily PigN PF04987.9 EAU82755.2 - 1.7e-102 343.3 34.3 8.1e-102 341.1 23.8 1.9 1 1 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EAU82755.2 - 7.8e-12 45.1 0.2 1.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAU82755.2 - 3.9e-05 22.9 0.0 8.5e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EAU82755.2 - 0.0008 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Arrestin_N PF00339.24 EAU82756.2 - 6e-10 39.1 0.0 1.5e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EAU82756.2 - 0.031 14.3 0.0 0.57 10.2 0.0 2.4 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain EVE PF01878.13 EAU82757.2 - 3.6e-46 156.7 0.0 6.6e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 EVE domain Paf1 PF03985.8 EAU82757.2 - 0.15 10.7 7.2 0.6 8.7 3.9 2.0 2 0 0 2 2 2 0 Paf1 UPF0104 PF03706.8 EAU82768.2 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF4381 PF14316.1 EAU82768.2 - 0.15 12.1 4.7 0.28 11.2 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Rifin_STEVOR PF02009.11 EAU82768.2 - 0.28 10.8 2.8 0.56 9.8 1.9 1.4 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EAU82768.2 - 0.33 11.3 0.0 0.71 10.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EAU82768.2 - 1.2 8.5 9.0 3 7.2 6.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain G-alpha PF00503.15 EAU82769.1 - 6.2e-122 407.0 0.0 7.8e-122 406.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU82769.1 - 2e-12 46.7 0.0 3.3e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EAU82769.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aminotran_1_2 PF00155.16 EAU82771.2 - 4.2e-45 154.2 0.0 5.4e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PBP1_TM PF14812.1 EAU82772.2 - 0.034 14.4 0.9 0.053 13.8 0.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4243 PF14027.1 EAU82773.1 - 6.3e-85 285.5 0.1 7.6e-85 285.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Beta-lactamase PF00144.19 EAU82774.1 - 2.4e-44 151.6 0.0 3.4e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Pyr_redox PF00070.22 EAU82775.2 - 1.1e-09 38.5 0.9 1.8e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU82775.2 - 3.4e-09 36.8 0.0 2.1e-08 34.2 0.0 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU82775.2 - 0.00058 18.8 0.4 0.051 12.4 0.0 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAU82775.2 - 0.0006 19.9 0.0 0.0013 18.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAU82775.2 - 0.037 12.9 0.1 1.4 7.7 0.1 2.1 1 1 1 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.13 EAU82775.2 - 0.15 12.0 0.0 0.48 10.4 0.0 1.9 1 1 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 EAU82776.1 - 1.4e-25 89.5 0.0 2e-09 36.5 0.0 3.4 3 0 0 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU82776.1 - 3.9e-16 58.7 0.1 2.1e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EAU82776.1 - 3.1e-09 36.6 0.0 3.9e-08 33.0 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAU82776.1 - 1.3e-05 25.2 0.3 0.0029 17.5 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAU82776.1 - 2.2e-05 24.2 0.1 0.0012 18.5 0.0 2.2 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EAU82776.1 - 0.0025 16.7 0.0 0.11 11.4 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF3584 PF12128.3 EAU82778.2 - 0.17 9.2 28.7 0.27 8.5 19.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EAU82778.2 - 4.6 5.8 29.7 1 7.9 14.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein 3Beta_HSD PF01073.14 EAU82779.2 - 8.2e-22 77.2 0.0 1e-20 73.5 0.0 2.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU82779.2 - 2.9e-08 32.9 0.0 4.5e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EAU82779.2 - 2.5e-06 27.1 0.0 5.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU82779.2 - 0.012 15.6 0.0 0.047 13.6 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EAU82779.2 - 0.014 14.2 0.0 0.034 13.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EAU82779.2 - 0.078 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4616 PF15394.1 EAU82785.2 - 0.00064 18.8 0.0 0.00064 18.8 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4616) Striatin PF08232.7 EAU82785.2 - 4.1 7.7 7.7 2.6 8.3 0.0 2.5 3 0 0 3 3 3 0 Striatin family Transposase_21 PF02992.9 EAU82786.2 - 1e-05 24.7 0.3 2.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EAU82786.2 - 1.8e-05 24.1 0.0 3.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Lar_restr_allev PF14354.1 EAU82786.2 - 1.6 9.0 6.2 0.68 10.2 0.1 3.1 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-CCHC_4 PF14392.1 EAU82797.2 - 0.0017 17.9 6.7 0.0092 15.6 0.9 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EAU82797.2 - 0.029 14.2 8.7 1 9.4 0.8 2.5 2 0 0 2 2 2 0 Zinc knuckle RVP_2 PF08284.6 EAU82797.2 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease PCI PF01399.22 EAU82800.1 - 2e-06 28.0 0.1 3.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 PCI domain HNH_2 PF13391.1 EAU82801.2 - 0.015 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease DUF1180 PF06679.7 EAU82802.1 - 0.0018 18.1 1.2 0.0018 18.1 0.8 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1180) Podoplanin PF05808.6 EAU82802.1 - 0.049 13.1 0.3 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Podoplanin SKG6 PF08693.5 EAU82802.1 - 0.089 12.1 2.8 0.21 10.9 2.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EAU82802.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_C1_2 PF03051.10 EAU82803.2 - 0.32 9.4 0.1 0.48 8.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase C1-like family GDPD PF03009.12 EAU82804.2 - 5.4e-24 85.0 0.3 4e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EAU82804.2 - 9.5e-05 22.4 0.6 0.00035 20.6 0.4 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PSDC PF12588.3 EAU82804.2 - 0.059 12.9 0.1 0.12 12.0 0.1 1.5 1 1 0 1 1 1 0 Phophatidylserine decarboxylase AAA_12 PF13087.1 EAU82805.2 - 1.3e-42 145.4 0.0 2.2e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU82805.2 - 1.2e-27 96.9 0.0 1.8e-26 93.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU82805.2 - 1.7e-06 27.6 0.1 6.8e-06 25.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAU82805.2 - 0.00038 20.0 0.0 0.068 12.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.16 EAU82805.2 - 0.0075 15.6 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Trp_DMAT PF11991.3 EAU82806.1 - 0.043 13.0 0.1 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase DUF3715 PF12509.3 EAU82806.1 - 0.074 12.8 0.5 0.1 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) DUF1213 PF06740.7 EAU82806.1 - 0.075 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) PBP_sp32 PF07222.7 EAU82806.1 - 0.4 9.8 3.5 0.48 9.5 2.4 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Spore_III_AF PF09581.5 EAU82806.1 - 0.44 10.3 3.4 0.55 10.0 2.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Sec62 PF03839.11 EAU82806.1 - 2.1 7.6 6.0 2.2 7.6 4.1 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Pkinase PF00069.20 EAU82808.2 - 6.9e-69 231.8 0.0 8.9e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU82808.2 - 6.4e-33 113.9 0.0 8.9e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CAP_N PF01213.14 EAU82808.2 - 0.076 12.2 0.1 0.076 12.2 0.1 2.7 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Kinase-like PF14531.1 EAU82808.2 - 0.15 10.9 0.0 0.44 9.4 0.0 1.5 1 1 1 2 2 2 0 Kinase-like Ribosomal_S26e PF01283.14 EAU82809.2 - 6.6e-52 174.5 8.7 7.8e-52 174.3 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EAU82809.2 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) PIG-P PF08510.7 EAU82812.1 - 0.61 9.7 2.7 11 5.6 0.4 2.1 1 1 1 2 2 2 0 PIG-P 3Beta_HSD PF01073.14 EAU82814.1 - 4.4e-28 97.7 0.0 1.8e-19 69.4 0.0 2.4 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU82814.1 - 6.2e-12 44.9 0.0 1.3e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EAU82814.1 - 2.8e-11 43.3 0.0 4.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EAU82814.1 - 1.8e-06 27.7 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAU82814.1 - 0.00017 21.5 0.1 0.00034 20.5 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EAU82814.1 - 0.00021 21.3 0.0 0.00078 19.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EAU82814.1 - 0.0098 14.8 0.0 0.021 13.7 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EAU82814.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 EAU82815.1 - 5.6e-28 97.4 0.0 1.6e-27 95.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAU82815.1 - 1.1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAU82815.1 - 2.1e-09 36.6 0.0 9e-09 34.6 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EAU82815.1 - 0.0002 20.3 0.0 0.0007 18.5 0.0 1.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EAU82815.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAU82815.1 - 0.0024 17.8 0.0 0.0087 15.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EAU82815.1 - 0.0026 17.8 0.1 0.022 14.7 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding Pkinase PF00069.20 EAU82816.2 - 0.18 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF4243 PF14027.1 EAU82817.2 - 2.9e-72 243.8 0.0 3.7e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Epimerase PF01370.16 EAU82818.1 - 3.6e-06 26.6 0.0 0.016 14.6 0.0 2.2 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU82818.1 - 0.00012 22.1 0.2 0.00051 20.0 0.2 2.1 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EAU82818.1 - 0.0003 19.7 0.1 0.0018 17.2 0.0 2.0 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.8 EAU82818.1 - 0.0012 18.1 0.1 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EAU82818.1 - 0.0081 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EAU82818.1 - 0.027 14.9 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent zf-PARP PF00645.13 EAU82819.1 - 1.7e-23 82.6 0.1 3.8e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region YfcL PF08891.6 EAU82819.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 YfcL protein MFS_1 PF07690.11 EAU82820.1 - 1.3e-13 50.3 20.9 1.9e-13 49.8 14.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAU82820.1 - 0.38 10.5 4.8 0.076 12.8 0.4 2.0 2 0 0 2 2 2 0 MFS_1 like family WD40 PF00400.27 EAU82822.2 - 2.7e-43 144.3 24.0 8.9e-10 38.0 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 EAU82822.2 - 2.7e-28 98.6 0.0 9.5e-28 96.9 0.0 1.8 1 1 0 1 1 1 1 TUP1-like enhancer of split eIF2A PF08662.6 EAU82822.2 - 0.011 15.4 0.0 0.073 12.7 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-C2H2_jaz PF12171.3 EAU82823.2 - 7.6e-19 67.3 15.3 0.00016 21.7 0.0 6.4 6 0 0 6 6 6 5 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EAU82823.2 - 3.5e-13 49.0 25.3 0.014 15.6 0.1 7.3 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-met PF12874.2 EAU82823.2 - 6.8e-12 45.1 15.5 0.00039 20.5 0.1 6.6 7 0 0 7 7 6 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EAU82823.2 - 5.6e-07 29.4 35.0 0.36 11.2 0.0 7.7 8 0 0 8 8 7 5 C2H2-type zinc finger zf-C3HC4_2 PF13923.1 EAU82823.2 - 5.4e-05 23.1 13.0 5.4e-05 23.1 9.0 4.1 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU82823.2 - 0.00023 20.7 13.0 0.00023 20.7 9.0 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU82823.2 - 0.0003 20.4 13.6 0.0003 20.4 9.4 4.0 2 1 2 4 4 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAU82823.2 - 0.0026 17.3 11.7 0.0026 17.3 8.1 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU82823.2 - 0.0046 16.7 12.3 0.0046 16.7 8.5 3.8 3 1 0 3 3 2 1 Ring finger domain zf-C2H2_6 PF13912.1 EAU82823.2 - 0.0087 15.9 0.0 0.0087 15.9 0.0 5.7 7 0 0 7 7 7 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EAU82823.2 - 0.01 15.9 20.1 2.8 8.1 0.1 5.9 1 1 5 6 6 6 0 C2H2 type zinc-finger (2 copies) zf-RING_6 PF14835.1 EAU82823.2 - 0.021 14.5 8.1 0.062 13.0 5.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF4336 PF14234.1 EAU82824.2 - 5.6e-13 48.7 0.0 5.3e-08 32.3 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) AMP_N PF05195.11 EAU82824.2 - 0.086 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Aldo_ket_red PF00248.16 EAU82827.2 - 1e-77 260.7 0.0 1.4e-77 260.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF647 PF04884.9 EAU82827.2 - 1.3e-68 230.9 2.8 2.3e-68 230.0 1.9 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis zf-DHHC PF01529.15 EAU82828.2 - 1 8.6 5.8 1.8 7.9 4.0 1.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase ABC_membrane_2 PF06472.10 EAU82829.1 - 2.6e-72 243.3 0.2 6.4e-72 242.0 0.0 1.7 2 1 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EAU82829.1 - 5.1e-18 65.6 0.0 1.1e-17 64.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EAU82829.1 - 0.019 14.7 0.0 0.092 12.5 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 EAU82829.1 - 0.028 13.6 0.0 2.4 7.3 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.16 EAU82829.1 - 0.041 13.0 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_26 PF13500.1 EAU82829.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lentiviral_Tat PF02998.9 EAU82830.2 - 0.0064 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Lentiviral Tat protein IF4E PF01652.13 EAU82831.1 - 2.9e-50 170.0 0.0 4e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glyco_transf_8 PF01501.15 EAU82832.1 - 3.7e-28 98.5 0.0 1.2e-27 96.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Methyltransf_24 PF13578.1 EAU82832.1 - 5.6e-18 65.7 0.0 1.7e-17 64.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EAU82832.1 - 3.3e-07 29.5 0.0 7.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EAU82832.1 - 0.044 14.3 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EAU82832.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 EAU82832.1 - 0.19 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) F-box-like PF12937.2 EAU82834.2 - 3e-05 23.6 2.4 7.3e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU82834.2 - 4.4e-05 23.0 3.9 0.00018 21.0 0.0 3.0 3 0 0 3 3 3 1 F-box domain DUF4246 PF14033.1 EAU82835.2 - 2.2e-181 603.8 0.0 2.6e-181 603.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EAU82835.2 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Histone PF00125.19 EAU82836.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU82836.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EAU82836.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EAU82836.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EAU82836.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EAU82836.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-C3HC4_3 PF13920.1 EAU82838.2 - 1.8e-06 27.5 4.4 2.8e-06 26.9 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU82838.2 - 1.2e-05 24.9 5.3 2e-05 24.2 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain RRM_6 PF14259.1 EAU82838.2 - 0.00039 20.3 0.0 0.00093 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EAU82838.2 - 0.0036 16.9 6.1 0.0066 16.0 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU82838.2 - 0.0039 17.0 6.6 0.007 16.1 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain RRM_1 PF00076.17 EAU82838.2 - 0.036 13.6 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EAU82838.2 - 0.065 13.2 7.4 0.11 12.4 5.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU82838.2 - 7.9 6.4 7.6 16 5.5 5.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING KIAA1328 PF15369.1 EAU82842.2 - 6.8 6.3 5.8 1.4 8.6 0.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 bZIP_1 PF00170.16 EAU82846.2 - 6.5e-05 22.8 9.2 0.00024 20.9 6.3 2.1 1 0 0 1 1 1 1 bZIP transcription factor Med15 PF09606.5 EAU82846.2 - 0.00022 19.5 59.1 0.00022 19.5 41.0 5.0 2 2 1 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal bZIP_2 PF07716.10 EAU82846.2 - 0.0027 17.5 7.0 0.0027 17.5 4.9 4.4 3 3 1 4 4 4 1 Basic region leucine zipper Metallothio_Cad PF07846.6 EAU82846.2 - 4.2 7.3 4.7 8 6.4 3.3 1.4 1 0 0 1 1 1 0 Metallothionein family WD40 PF00400.27 EAU82848.1 - 1.8e-32 109.9 15.6 1.9e-08 33.8 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF1180 PF06679.7 EAU82849.1 - 4.1 7.2 9.6 4.6 7.1 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) F-box-like PF12937.2 EAU82857.1 - 0.012 15.3 0.2 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 F-box-like AAA_12 PF13087.1 EAU82858.2 - 4.7e-45 153.4 0.0 8.5e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU82858.2 - 1.2e-29 103.6 0.0 1.4e-13 50.9 0.0 3.2 2 2 1 3 3 3 2 AAA domain AAA_30 PF13604.1 EAU82858.2 - 2.1e-10 40.5 0.0 6.1e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU82858.2 - 3.2e-10 39.5 0.0 1e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 EAU82858.2 - 0.00011 21.6 0.0 0.0078 15.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EAU82858.2 - 0.00018 21.0 0.1 0.026 14.0 0.0 2.4 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EAU82858.2 - 0.0021 18.1 0.0 0.007 16.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EAU82858.2 - 0.0027 17.7 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EAU82858.2 - 0.0082 15.1 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EAU82858.2 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 EAU82858.2 - 0.02 13.8 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.10 EAU82858.2 - 0.025 14.4 0.0 0.062 13.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.24 EAU82858.2 - 0.042 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAU82858.2 - 0.047 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 EAU82858.2 - 0.047 12.9 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Wyosine_form PF08608.7 EAU82858.2 - 0.088 12.9 0.1 2.2 8.4 0.0 2.7 3 0 0 3 3 2 0 Wyosine base formation CTP_synth_N PF06418.9 EAU82860.1 - 1.7e-117 391.4 0.6 2.2e-117 391.0 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EAU82860.1 - 3.9e-46 156.9 0.0 6.5e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAU82860.1 - 0.00017 21.1 0.0 0.0004 19.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EAU82860.1 - 0.0019 17.6 0.0 0.0049 16.3 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ELFV_dehydrog PF00208.16 EAU82861.1 - 1.5e-73 247.3 0.2 1.8e-73 247.0 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EAU82861.1 - 3.6e-48 162.4 0.0 7.1e-48 161.5 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain F-box PF00646.28 EAU82864.2 - 1.2e-07 31.1 2.1 2.4e-07 30.2 1.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU82864.2 - 2.1e-06 27.3 2.2 5.5e-06 26.0 1.5 1.7 1 0 0 1 1 1 1 F-box-like Pribosyltran PF00156.22 EAU82866.2 - 8.6e-18 64.2 0.2 1.2e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C2H2 PF00096.21 EAU82867.1 - 0.0091 16.2 0.1 0.0091 16.2 0.1 2.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU82867.1 - 0.011 16.0 0.1 0.03 14.6 0.0 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger AA_kinase PF00696.23 EAU82868.2 - 6.3e-36 124.1 0.1 2.4e-30 105.8 0.0 2.2 2 0 0 2 2 2 2 Amino acid kinase family ACT_7 PF13840.1 EAU82868.2 - 3.6e-15 55.2 3.8 1.1e-12 47.3 0.4 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EAU82868.2 - 4e-12 45.3 0.9 5.7e-07 28.8 0.1 2.8 2 0 0 2 2 2 2 ACT domain F-box-like PF12937.2 EAU82869.1 - 6.3e-07 29.0 0.0 2e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU82869.1 - 7.8e-05 22.2 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EAU82869.1 - 0.83 9.3 10.2 2 8.1 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF1387 PF07139.6 EAU82869.1 - 2.3 7.7 7.4 4 6.9 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) zf-C2H2_4 PF13894.1 EAU82870.1 - 1e-08 34.8 9.9 0.0078 16.4 0.2 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU82870.1 - 2.4e-08 33.8 8.9 0.00042 20.4 0.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU82870.1 - 0.00017 21.7 14.0 0.6 10.5 0.2 4.4 3 1 1 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EAU82870.1 - 0.0069 16.4 5.7 0.011 15.8 1.9 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EAU82870.1 - 0.009 16.1 9.1 0.055 13.7 0.2 3.7 3 1 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EAU82870.1 - 0.065 13.3 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3505 PF12013.3 EAU82870.1 - 0.08 13.1 1.5 0.8 9.9 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) zf-BED PF02892.10 EAU82870.1 - 0.67 9.7 4.8 2.1 8.1 0.0 3.0 3 0 0 3 3 3 0 BED zinc finger FlaC_arch PF05377.6 EAU82872.1 - 0.0035 17.1 1.6 0.016 15.0 0.3 2.4 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Vac_Fusion PF02346.11 EAU82872.1 - 0.019 14.3 1.5 0.095 12.1 0.1 2.9 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF1664 PF07889.7 EAU82872.1 - 2.3 7.9 6.0 0.76 9.5 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF681 PF05080.7 EAU82873.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF681) AF1Q PF15017.1 EAU82873.1 - 2 8.3 11.2 1.1 9.1 5.7 2.0 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Tet_JBP PF12851.2 EAU82875.2 - 1.1e-12 47.5 0.0 1.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EAU82875.2 - 0.0045 17.4 0.1 0.0098 16.3 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EAU82876.2 - 7e-72 242.4 0.0 1.1e-71 241.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M24 PF00557.19 EAU82877.1 - 2.6e-44 151.3 0.0 3.7e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EAU82877.1 - 1.4e-27 96.7 0.0 1.1e-20 74.5 0.0 2.7 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Oxysterol_BP PF01237.13 EAU82879.1 - 1.9e-53 181.1 0.0 4.2e-41 140.6 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein SRI PF08236.6 EAU82879.1 - 0.078 12.9 0.4 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain MIP PF00230.15 EAU82880.2 - 4.2e-44 150.7 5.4 9.1e-42 143.0 3.8 2.0 1 1 0 1 1 1 1 Major intrinsic protein AAA PF00004.24 EAU82882.2 - 3.4e-44 150.2 0.0 6.5e-44 149.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EAU82882.2 - 1.6e-08 34.6 0.0 4.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAU82882.2 - 1.1e-06 28.4 0.0 5.6e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAU82882.2 - 3.7e-06 27.0 0.3 1.3e-05 25.2 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU82882.2 - 5.6e-06 26.5 0.3 0.0003 20.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EAU82882.2 - 5.1e-05 22.9 0.1 0.00016 21.3 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 EAU82882.2 - 5.7e-05 23.9 0.0 0.00017 22.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAU82882.2 - 7.8e-05 21.8 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EAU82882.2 - 0.00036 19.9 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EAU82882.2 - 0.00083 18.1 0.0 0.0016 17.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EAU82882.2 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU82882.2 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAU82882.2 - 0.002 17.2 0.0 0.0046 16.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EAU82882.2 - 0.0032 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU82882.2 - 0.0034 17.6 0.2 0.026 14.8 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.6 EAU82882.2 - 0.0036 16.8 0.0 0.0079 15.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EAU82882.2 - 0.0037 16.5 0.0 0.065 12.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EAU82882.2 - 0.0058 15.8 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EAU82882.2 - 0.014 14.5 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EAU82882.2 - 0.015 14.7 0.1 0.087 12.2 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 EAU82882.2 - 0.021 14.2 0.1 0.079 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EAU82882.2 - 0.022 13.7 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EAU82882.2 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAU82882.2 - 0.033 14.3 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EAU82882.2 - 0.041 13.5 0.0 0.56 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 EAU82882.2 - 0.047 13.7 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EAU82882.2 - 0.052 12.4 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 BBS2_C PF14782.1 EAU82882.2 - 0.055 12.0 0.3 0.084 11.4 0.2 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal NB-ARC PF00931.17 EAU82882.2 - 0.096 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RdRP PF05183.7 EAU82883.2 - 5.3e-176 586.7 0.0 8e-176 586.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Exonuc_X-T_C PF08411.5 EAU82884.2 - 0.17 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal G-alpha PF00503.15 EAU82885.2 - 1.3e-158 527.8 0.0 1.5e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU82885.2 - 1.9e-06 27.2 0.1 0.0032 16.7 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EAU82885.2 - 0.0039 16.6 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_12 PF13087.1 EAU82886.2 - 8.2e-44 149.3 0.0 1.7e-43 148.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EAU82886.2 - 9.7e-34 116.9 0.1 3.1e-16 59.6 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EAU82886.2 - 4.4e-13 49.2 0.0 1.1e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU82886.2 - 1.5e-11 43.8 0.0 3.7e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 EAU82886.2 - 2.3e-07 30.4 0.0 0.00031 20.1 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EAU82886.2 - 0.00017 20.8 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 EAU82886.2 - 0.00037 20.3 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU82886.2 - 0.00048 20.2 0.0 0.0047 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EAU82886.2 - 0.00097 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EAU82886.2 - 0.0043 17.0 0.0 0.0086 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 EAU82886.2 - 0.0051 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EAU82886.2 - 0.0073 15.8 0.0 8.3 5.8 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EAU82886.2 - 0.03 14.5 0.0 0.087 13.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EAU82886.2 - 0.068 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EAU82886.2 - 0.086 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain UvrD_C PF13361.1 EAU82886.2 - 0.097 12.1 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.16 EAU82886.2 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.9 EAU82886.2 - 0.16 10.9 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase T2SE PF00437.15 EAU82886.2 - 0.17 10.7 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ERG4_ERG24 PF01222.12 EAU82887.2 - 3.1e-111 371.9 7.0 4.2e-111 371.5 4.7 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EAU82887.2 - 3.7e-05 23.1 0.5 9.3e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EAU82887.2 - 8.3e-05 22.6 0.9 0.00028 20.9 0.1 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EAU82887.2 - 0.0068 16.5 0.9 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FAD_binding_4 PF01565.18 EAU82888.1 - 4.3e-23 81.3 0.4 8e-23 80.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU82888.1 - 8.1e-12 44.8 0.1 2.1e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Carboxyl_trans PF01039.17 EAU82889.2 - 2.8e-83 279.9 0.0 5.1e-83 279.0 0.0 1.4 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EAU82890.2 - 8.2e-55 185.3 0.0 1.2e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EAU82890.2 - 1.4e-22 79.7 0.0 1.1e-21 76.8 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EAU82890.2 - 3.4e-20 72.5 0.0 8e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_chain PF00289.17 EAU82890.2 - 4.1e-16 59.0 0.2 1.6e-13 50.7 0.0 2.6 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EAU82890.2 - 1.3e-09 37.2 0.0 0.00053 18.8 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EAU82890.2 - 7e-09 35.2 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAU82890.2 - 2.4e-08 33.6 0.0 4.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 EAU82890.2 - 7.5e-07 28.6 1.1 1.9e-06 27.4 0.7 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_2 PF08442.5 EAU82890.2 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.9 EAU82890.2 - 0.06 13.2 0.2 0.6 9.9 0.1 2.2 1 1 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EAU82890.2 - 0.18 11.2 0.0 1.3 8.4 0.0 2.3 2 1 0 2 2 2 0 RimK-like ATP-grasp domain FA_desaturase PF00487.19 EAU82891.1 - 1.6e-26 93.3 11.8 2.4e-26 92.7 8.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EAU82891.1 - 5.3e-18 63.9 0.5 9.7e-18 63.1 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) HLH PF00010.21 EAU82892.1 - 2.1e-11 43.3 0.0 6.2e-11 41.8 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AT_hook PF02178.14 EAU82892.1 - 0.39 10.5 7.6 1.6 8.6 5.3 2.2 1 0 0 1 1 1 0 AT hook motif DAO PF01266.19 EAU82893.1 - 1.8e-20 73.1 0.0 2.2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAU82893.1 - 0.0057 16.5 0.0 0.018 14.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU82893.1 - 0.016 15.2 0.3 0.043 13.8 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU82893.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EAU82893.1 - 0.071 13.5 1.5 0.13 12.7 0.5 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EAU82893.1 - 0.1 12.0 0.3 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CBM_21 PF03370.8 EAU82894.1 - 8.3e-15 54.7 0.9 1.6e-14 53.8 0.6 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Alpha-amylase PF00128.19 EAU82894.1 - 2.4e-14 53.4 0.0 5e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CDC45 PF02724.9 EAU82895.2 - 0.098 10.6 3.1 0.15 10.0 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.4 EAU82895.2 - 4.4 6.9 13.1 10 5.7 9.1 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DEAD PF00270.24 EAU82896.2 - 1.3e-38 132.1 0.3 4.1e-38 130.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU82896.2 - 9e-18 63.9 0.0 2e-15 56.4 0.1 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EAU82896.2 - 0.0018 18.1 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EAU82896.2 - 0.0021 16.5 0.1 0.0097 14.3 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) FAD_binding_4 PF01565.18 EAU82898.1 - 2.9e-22 78.6 0.8 5.1e-22 77.8 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU82898.1 - 1.4e-11 44.1 0.3 3.5e-11 42.8 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like DER1 PF04511.10 EAU82899.2 - 1.3e-13 50.8 4.1 1.7e-08 34.1 0.4 2.1 2 0 0 2 2 2 2 Der1-like family DER1 PF04511.10 EAU82900.1 - 1.1e-30 106.6 0.7 1.4e-30 106.3 0.5 1.0 1 0 0 1 1 1 1 Der1-like family Ycf4 PF02392.11 EAU82900.1 - 3.5 6.8 4.5 9.4 5.5 0.2 2.1 2 0 0 2 2 2 0 Ycf4 AAA_12 PF13087.1 EAU82902.2 - 2.5e-45 154.3 0.0 3.9e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU82902.2 - 1.3e-30 106.7 0.1 8.4e-14 51.7 0.0 3.2 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EAU82902.2 - 1e-11 44.4 0.0 2.4e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAU82902.2 - 2.2e-11 43.7 0.0 6.3e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EAU82902.2 - 2.3e-05 23.8 0.0 0.024 13.9 0.0 2.3 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EAU82902.2 - 0.00055 19.5 0.0 4.6 6.6 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EAU82902.2 - 0.004 17.2 0.0 0.022 14.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF3505 PF12013.3 EAU82902.2 - 0.0098 16.1 1.0 4.2 7.6 0.3 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3505) PhoH PF02562.11 EAU82902.2 - 0.024 13.8 0.0 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 EAU82902.2 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EAU82902.2 - 0.091 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EAU82902.2 - 0.1 12.5 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.10 EAU82902.2 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD_C PF13361.1 EAU82902.2 - 0.11 11.9 0.1 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Phytase PF02333.10 EAU82906.2 - 2.7e-52 177.7 0.7 4e-52 177.2 0.1 1.5 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.8 EAU82906.2 - 3.7e-07 30.1 26.4 0.00011 22.2 9.5 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EAU82906.2 - 0.0029 17.5 16.8 0.017 15.1 4.3 2.8 2 0 0 2 2 2 2 Human growth factor-like EGF PQQ_3 PF13570.1 EAU82906.2 - 0.084 13.1 1.6 0.32 11.3 0.2 2.8 2 0 0 2 2 2 0 PQQ-like domain EGF PF00008.22 EAU82906.2 - 1.3 9.0 22.9 4.1 7.4 2.0 2.6 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 EAU82906.2 - 5.2 7.0 19.3 0.57 10.1 1.8 2.5 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF_alliinase PF04863.8 EAU82906.2 - 6.7 6.7 13.0 1.5 8.9 2.1 2.8 1 1 1 2 2 2 0 Alliinase EGF-like domain Mg_trans_NIPA PF05653.9 EAU82908.2 - 1.5e-97 326.1 16.6 5.6e-97 324.3 11.5 1.7 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EAU82908.2 - 3.8e-05 23.8 1.3 3.8e-05 23.8 0.9 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF2283 PF10049.4 EAU82908.2 - 4 7.3 5.0 3.1 7.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2283) Activator_LAG-3 PF11498.3 EAU82909.2 - 0.39 9.4 13.3 0.37 9.4 8.9 1.3 1 1 0 1 1 1 0 Transcriptional activator LAG-3 DUF2046 PF09755.4 EAU82911.1 - 2.2e-11 43.2 8.6 7.1e-11 41.5 4.7 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) TORC_N PF12884.2 EAU82911.1 - 0.024 15.1 0.3 0.073 13.6 0.2 1.8 1 0 0 1 1 1 0 Transducer of regulated CREB activity, N terminus Spc24 PF08286.6 EAU82911.1 - 0.99 9.1 4.9 1.6 8.4 1.0 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Abhydrolase_6 PF12697.2 EAU82912.1 - 2.6e-25 89.6 0.0 4.1e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU82912.1 - 3.8e-14 52.7 0.0 1.1e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU82912.1 - 1.8e-11 43.9 0.0 2.9e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EAU82912.1 - 0.018 13.5 0.0 0.026 13.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family DLH PF01738.13 EAU82912.1 - 0.018 14.3 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EAU82912.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 EAU82912.1 - 0.11 12.6 0.1 1.4 9.0 0.1 2.2 1 1 1 2 2 2 0 Thioesterase domain DUF89 PF01937.14 EAU82914.2 - 4.2e-101 338.2 0.1 5.9e-101 337.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 WW PF00397.21 EAU82915.2 - 3.9e-09 36.1 6.5 9.3e-09 35.0 4.5 1.7 1 0 0 1 1 1 1 WW domain UNC-50 PF05216.8 EAU82916.2 - 1e-84 283.4 13.6 1.1e-84 283.2 9.4 1.0 1 0 0 1 1 1 1 UNC-50 family PepSY_TM PF03929.11 EAU82916.2 - 0.19 12.1 0.2 0.19 12.1 0.1 3.8 4 1 0 4 4 4 0 PepSY-associated TM helix Metallophos PF00149.23 EAU82917.1 - 1.1e-42 145.7 0.5 1.8e-42 145.0 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CorA PF01544.13 EAU82919.2 - 0.022 13.7 3.3 0.63 9.0 0.0 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein LRR_8 PF13855.1 EAU82921.2 - 0.00041 20.0 2.4 0.012 15.3 0.0 3.3 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 EAU82921.2 - 0.0061 16.1 0.2 3.2 7.4 0.0 3.1 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) NUDIX PF00293.23 EAU82922.2 - 1.3e-07 31.3 0.0 2.3e-07 30.4 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain FDC-SP PF15215.1 EAU82922.2 - 0.44 10.8 0.1 0.44 10.8 0.1 2.3 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide IATP PF04568.7 EAU82926.1 - 0.25 11.3 0.6 0.42 10.6 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF2034 PF10356.4 EAU82927.1 - 2e-29 102.0 0.0 1e-28 99.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EAU82927.1 - 2.2e-06 27.4 0.0 5.8e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Restriction endonuclease G-alpha PF00503.15 EAU82928.2 - 1e-80 271.3 0.1 2e-43 148.5 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EAU82928.2 - 0.09 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family LRR_6 PF13516.1 EAU82930.2 - 0.023 14.7 0.8 1.3e+02 3.1 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.2 EAU82930.2 - 0.033 13.8 7.5 1.9 8.2 1.1 5.1 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) PRANC PF09372.5 EAU82930.2 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Glyco_hydro_10 PF00331.15 EAU82931.1 - 5.3e-100 334.5 0.0 6.4e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 EAU82931.1 - 0.071 13.5 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like Ureidogly_hydro PF04115.7 EAU82931.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ureidoglycolate hydrolase Ank PF00023.25 EAU82932.2 - 2e-56 185.1 11.2 1.4e-06 27.8 0.0 12.8 13 0 0 13 13 13 11 Ankyrin repeat Ank_2 PF12796.2 EAU82932.2 - 4.8e-56 187.0 11.5 2.3e-13 50.2 0.1 7.6 3 2 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU82932.2 - 3.1e-47 157.5 12.4 1.7e-09 37.5 0.0 10.3 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU82932.2 - 1.6e-45 152.6 9.1 3.5e-08 33.7 0.0 10.3 4 2 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU82932.2 - 1.6e-38 126.8 5.2 0.0047 17.0 0.0 12.7 12 0 0 12 12 12 9 Ankyrin repeat AAA_16 PF13191.1 EAU82932.2 - 1.3e-06 28.5 0.2 7.7e-05 22.7 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EAU82932.2 - 9.1e-05 22.6 0.0 0.0016 18.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EAU82932.2 - 0.00012 21.7 0.0 0.00038 20.1 0.0 1.9 1 1 0 1 1 1 1 NACHT domain NapD PF03927.8 EAU82932.2 - 0.0013 18.4 0.1 4.6 7.1 0.0 5.3 4 2 1 5 5 5 1 NapD protein APS_kinase PF01583.15 EAU82932.2 - 0.028 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2075 PF09848.4 EAU82932.2 - 0.041 12.8 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EAU82932.2 - 0.064 14.0 0.1 0.33 11.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain Ank_5 PF13857.1 EAU82933.1 - 5e-19 67.8 0.2 3.5e-09 36.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EAU82933.1 - 7.1e-16 57.1 0.2 0.00063 19.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EAU82933.1 - 1.3e-15 57.4 0.0 1.5e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU82933.1 - 1.1e-13 51.2 0.2 6.3e-06 26.5 0.0 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU82933.1 - 5e-09 35.5 0.0 0.0074 16.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat DUF1874 PF08960.5 EAU82933.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) DUF964 PF06133.6 EAU82934.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DAO PF01266.19 EAU82934.1 - 0.1 11.4 0.5 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF2611 PF11022.3 EAU82935.2 - 1.3e-13 50.7 0.1 4.2e-13 49.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) Mito_carr PF00153.22 EAU82936.2 - 5.9e-61 202.2 0.9 9e-22 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ni_hydr_CYTB PF01292.15 EAU82937.1 - 0.15 11.4 5.5 0.12 11.7 2.2 1.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Neurokinin_B PF03823.9 EAU82937.1 - 0.9 9.3 4.4 1.2 8.9 0.1 2.7 3 0 0 3 3 3 0 Neurokinin B Sigma_reg_N PF13800.1 EAU82939.2 - 0.74 9.8 0.0 0.74 9.8 0.0 2.3 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Exo70 PF03081.10 EAU82941.2 - 3.5e-42 144.5 0.0 6e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit CCT_2 PF09425.5 EAU82941.2 - 0.052 13.1 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Divergent CCT motif CCT PF06203.9 EAU82941.2 - 0.09 12.4 0.2 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 CCT motif Barttin PF15462.1 EAU82945.2 - 0.0081 15.8 0.9 0.012 15.2 0.7 1.2 1 0 0 1 1 1 1 Bartter syndrome, infantile, with sensorineural deafness (Barttin) MTBP_C PF14920.1 EAU82945.2 - 0.064 12.7 2.5 0.13 11.6 1.7 1.5 1 0 0 1 1 1 0 MDM2-binding PSDC PF12588.3 EAU82946.1 - 1.3e-40 138.3 0.0 2e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAU82946.1 - 1.1e-35 122.8 0.0 1.6e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase BTB PF00651.26 EAU82947.1 - 2.4e-07 30.7 0.0 3.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain U79_P34 PF03064.11 EAU82948.2 - 0.0074 15.8 0.4 0.026 14.0 0.3 1.9 1 0 0 1 1 1 1 HSV U79 / HCMV P34 PilP PF04351.8 EAU82948.2 - 1.7 8.5 6.6 0.077 12.8 0.4 1.7 2 0 0 2 2 2 0 Pilus assembly protein, PilP zf-MYND PF01753.13 EAU82949.2 - 1e-07 31.6 13.1 2e-07 30.7 9.1 1.5 1 0 0 1 1 1 1 MYND finger BTB PF00651.26 EAU82950.2 - 1.7e-11 44.0 0.1 5.3e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain CBFD_NFYB_HMF PF00808.18 EAU82951.1 - 4.6e-28 97.0 0.7 7.6e-28 96.3 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAU82951.1 - 4.6e-06 26.6 0.1 8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EAU82951.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EAU82951.1 - 0.051 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Peptidase_M36 PF02128.10 EAU82952.2 - 1.3e-65 221.7 0.2 4.7e-32 111.2 0.1 2.5 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) PepSY PF03413.14 EAU82952.2 - 0.028 15.0 0.4 0.2 12.2 0.0 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Barttin PF15462.1 EAU82954.2 - 0.026 14.1 1.1 0.039 13.6 0.8 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Pap_E4 PF02711.9 EAU82954.2 - 0.19 12.5 1.5 0.34 11.7 1.0 1.4 1 0 0 1 1 1 0 E4 protein Peptidase_M36 PF02128.10 EAU82955.2 - 2.8e-87 293.0 3.1 2.6e-86 289.8 2.2 2.0 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_MA_2 PF13485.1 EAU82955.2 - 0.039 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily PepSY PF03413.14 EAU82955.2 - 0.039 14.6 0.1 0.076 13.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain FTP PF07504.8 EAU82955.2 - 0.065 12.7 0.1 0.18 11.2 0.1 1.7 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DUF1777 PF08648.7 EAU82958.2 - 0.0002 21.1 64.7 0.021 14.5 12.3 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF1777) CPSF_A PF03178.10 EAU82960.1 - 8.6e-79 264.9 0.0 1.4e-78 264.2 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region Peptidase_M36 PF02128.10 EAU82961.1 - 9.4e-113 376.8 5.3 1.2e-112 376.5 3.7 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M4_C PF02868.10 EAU82961.1 - 0.0011 18.6 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 EAU82961.1 - 0.022 14.7 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase MA superfamily Beta-lactamase PF00144.19 EAU82962.2 - 9.4e-07 28.1 0.0 1.7e-06 27.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase DUF3856 PF12968.2 EAU82964.1 - 0.031 14.1 0.3 0.045 13.5 0.2 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) ATP_bind_1 PF03029.12 EAU82965.1 - 1.2e-75 254.1 0.0 1.4e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EAU82965.1 - 0.07 13.9 0.9 0.53 11.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU82965.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EAU82965.1 - 0.16 11.9 0.7 1.7 8.6 0.5 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EAU82967.2 - 1e-22 80.8 0.0 1.3e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU82967.2 - 8.8e-08 33.0 0.1 2.4e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU82967.2 - 9.6e-07 29.1 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAU82967.2 - 1.8e-05 24.9 0.0 2.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU82967.2 - 0.00038 20.4 0.0 0.00076 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EAU82967.2 - 0.00051 19.7 0.1 0.00091 18.9 0.1 1.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EAU82967.2 - 0.00074 19.4 0.3 0.0036 17.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EAU82967.2 - 0.0052 16.9 0.0 0.0092 16.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EAU82967.2 - 0.0072 16.4 0.4 0.029 14.4 0.3 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EAU82967.2 - 0.0079 16.4 0.0 0.013 15.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter RHH_1 PF01402.16 EAU82967.2 - 0.02 14.7 0.2 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Rad17 PF03215.10 EAU82967.2 - 0.024 13.3 0.0 0.03 12.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 EAU82967.2 - 0.027 14.1 0.0 0.05 13.2 0.0 1.5 1 1 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EAU82967.2 - 0.027 13.8 0.1 0.1 11.9 0.1 1.9 1 1 0 1 1 1 0 Thymidylate kinase MMR_HSR1 PF01926.18 EAU82967.2 - 0.039 13.9 0.0 0.047 13.6 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin2 PF13189.1 EAU82967.2 - 0.043 13.7 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family PduV-EutP PF10662.4 EAU82967.2 - 0.053 13.0 0.1 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2121 PF09894.4 EAU82967.2 - 0.06 12.6 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) AAA_14 PF13173.1 EAU82967.2 - 0.076 12.9 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAU82967.2 - 0.093 12.4 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain Guanylate_kin PF00625.16 EAU82967.2 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_PrkA PF08298.6 EAU82967.2 - 0.13 10.8 0.0 0.22 10.1 0.0 1.5 1 1 0 1 1 1 0 PrkA AAA domain GTP_EFTU PF00009.22 EAU82967.2 - 0.14 11.5 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RdRP PF05183.7 EAU82968.2 - 5.1e-81 273.1 0.7 3e-49 168.2 0.0 2.2 2 0 0 2 2 2 2 RNA dependent RNA polymerase AAA_12 PF13087.1 EAU82968.2 - 3.3e-41 140.8 0.0 6.5e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU82968.2 - 2.5e-07 30.5 2.0 0.0048 16.4 0.1 3.3 1 1 2 3 3 3 2 AAA domain CoA_transf_3 PF02515.12 EAU82969.2 - 1.6e-26 92.7 0.0 6.1e-25 87.5 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III WD40 PF00400.27 EAU82970.2 - 9.9e-17 60.1 6.5 0.00083 19.1 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 EAU82970.2 - 6.7e-09 35.6 0.0 1.8e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EAU82970.2 - 0.032 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 EAU82970.2 - 0.088 12.3 0.7 4.5 6.8 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CMV_1a PF12467.3 EAU82970.2 - 2 8.7 9.6 0.61 10.4 4.2 1.8 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family PSDC PF12588.3 EAU82973.2 - 4.1e-39 133.4 0.0 6.5e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAU82973.2 - 2.8e-34 118.1 0.0 4.2e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PTS_EIIA_1 PF00358.15 EAU82973.2 - 0.11 12.0 0.0 8.2 5.9 0.0 2.3 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.1 EAU82973.2 - 0.14 11.8 0.0 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain SET PF00856.23 EAU82974.2 - 1.2e-15 58.1 0.0 3e-14 53.6 0.0 2.4 1 1 0 1 1 1 1 SET domain PSDC PF12588.3 EAU82975.1 - 5.9e-38 129.6 0.0 9.6e-38 128.9 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAU82975.1 - 1.1e-33 116.2 0.0 1.5e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 EAU82975.1 - 0.08 12.6 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PSDC PF12588.3 EAU82976.1 - 1.1e-43 148.1 0.0 1.8e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAU82976.1 - 3.4e-34 117.9 0.0 4.9e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF1620 PF07774.8 EAU82976.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1620) PSDC PF12588.3 EAU82978.1 - 5.6e-42 142.6 0.1 8.4e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAU82978.1 - 3.6e-35 121.0 0.0 5.1e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PTS_EIIA_1 PF00358.15 EAU82978.1 - 0.045 13.3 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.17 EAU82978.1 - 0.081 12.9 0.1 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M23 RnfC_N PF13375.1 EAU82978.1 - 0.1 12.3 0.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain PSDC PF12588.3 EAU82979.1 - 5.2e-40 136.3 0.0 1.1e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAU82979.1 - 9.3e-37 126.2 0.0 1.3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 EAU82979.1 - 0.16 12.0 0.2 0.8 9.7 0.0 2.3 3 0 0 3 3 3 0 Peptidase family M23 SNF2_N PF00176.18 EAU82980.1 - 2.1e-06 26.7 0.0 3.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SNF2_N PF00176.18 EAU82981.2 - 4.8e-38 130.6 0.6 8.6e-38 129.8 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU82981.2 - 2.4e-11 43.3 0.0 5.1e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EAU82981.2 - 4e-08 32.7 7.7 7.8e-08 31.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU82981.2 - 9.4e-08 31.6 4.8 1.8e-07 30.7 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU82981.2 - 9.5e-08 31.7 6.4 1.8e-07 30.8 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAU82981.2 - 7.6e-06 25.5 6.5 1.6e-05 24.5 4.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAU82981.2 - 1e-05 25.4 7.1 2.2e-05 24.4 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU82981.2 - 0.003 17.2 0.8 0.0078 15.9 0.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-4CXXC_R1 PF10497.4 EAU82981.2 - 0.0063 16.6 1.3 0.018 15.1 0.9 1.8 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_6 PF14835.1 EAU82981.2 - 0.0099 15.6 1.0 0.035 13.9 0.7 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TFIIA PF03153.8 EAU82981.2 - 0.026 14.4 11.6 0.052 13.4 8.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.1 EAU82981.2 - 0.042 13.7 7.0 0.11 12.4 4.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EAU82981.2 - 0.062 12.8 6.7 0.14 11.7 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EAU82981.2 - 0.22 11.6 5.6 1.3 9.2 3.9 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger SPT6_acidic PF14632.1 EAU82981.2 - 1.7 8.8 52.6 2 8.6 2.3 4.6 3 1 1 4 4 4 0 Acidic N-terminal SPT6 FA_desaturase PF00487.19 EAU82982.2 - 2.3e-14 53.4 23.7 4.1e-08 32.9 6.1 3.0 2 1 2 4 4 4 2 Fatty acid desaturase DUF3474 PF11960.3 EAU82982.2 - 3.3e-06 27.1 0.0 6.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Sec63 PF02889.11 EAU82983.1 - 7.9e-194 642.9 0.0 4.6e-103 344.7 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EAU82983.1 - 1.7e-40 138.2 0.9 6.6e-19 68.0 0.2 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU82983.1 - 4.1e-12 45.7 0.0 1.2e-09 37.9 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU82983.1 - 6.9e-11 42.3 0.4 9.1e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU82983.1 - 0.00056 20.0 0.1 0.75 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EAU82983.1 - 0.0021 17.3 0.0 0.0047 16.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein Daxx PF03344.10 EAU82984.1 - 0.18 10.2 11.5 0.4 9.1 8.0 1.6 1 0 0 1 1 1 0 Daxx Family UDG PF03167.14 EAU82985.2 - 5.1e-05 22.7 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Trp_oprn_chp PF09534.5 EAU82987.2 - 0.11 12.1 7.4 0.062 12.9 1.0 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Fer2_3 PF13085.1 EAU82988.1 - 1.1e-33 115.3 0.1 1.7e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EAU82988.1 - 2.8e-11 43.5 8.1 2.8e-11 43.5 5.6 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EAU82988.1 - 4.5e-09 36.1 6.4 4.5e-09 36.1 4.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EAU82988.1 - 0.00016 22.0 4.8 0.00016 22.0 3.3 2.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EAU82988.1 - 0.00018 21.7 5.5 0.048 13.9 0.5 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 EAU82988.1 - 0.0011 19.3 6.2 0.0011 19.3 4.3 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EAU82988.1 - 0.0033 17.1 0.4 0.0033 17.1 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.1 EAU82988.1 - 0.0058 16.4 11.1 0.0063 16.2 5.7 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain F-box-like PF12937.2 EAU82989.1 - 7.1e-06 25.6 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like PAP2 PF01569.16 EAU82992.1 - 3.6e-18 65.4 9.0 1.3e-17 63.7 6.2 1.9 1 0 0 1 1 1 1 PAP2 superfamily DUF2204 PF09970.4 EAU82993.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) PPDFL PF15060.1 EAU82993.1 - 0.18 11.8 0.2 0.32 11.0 0.2 1.3 1 0 0 1 1 1 0 Differentiation and proliferation regulator DUF1282 PF06930.7 EAU82999.2 - 0.0062 16.2 0.2 0.0099 15.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) DUF3678 PF12435.3 EAU83000.2 - 0.76 9.3 0.0 0.76 9.3 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3678) DUF3306 PF11748.3 EAU83000.2 - 3.9 8.1 7.9 1.9 9.1 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3306) CorA PF01544.13 EAU83001.2 - 0.0019 17.2 0.9 0.0042 16.1 0.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 EAU83003.1 - 0.01 14.9 2.7 0.019 14.0 1.9 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Abi PF02517.11 EAU83003.1 - 0.11 12.6 2.0 0.37 10.9 1.4 1.7 1 1 0 1 1 1 0 CAAX protease self-immunity MLANA PF14991.1 EAU83003.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A CD99L2 PF12301.3 EAU83004.1 - 0.4 10.3 2.8 0.66 9.6 0.9 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 UPF0203 PF05254.7 EAU83005.1 - 1.2e-18 66.7 1.0 3.1e-18 65.3 0.7 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EAU83005.1 - 0.083 12.8 1.4 5.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF448 PF04296.8 EAU83005.1 - 0.086 12.4 0.2 2.3 7.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF448) Methyltrn_RNA_2 PF04013.7 EAU83005.1 - 0.087 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase COX6B PF02297.12 EAU83005.1 - 0.12 12.3 3.8 1.2 9.2 0.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb p450 PF00067.17 EAU83008.2 - 1.4e-63 215.0 0.0 3.5e-63 213.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_11 PF00457.12 EAU83009.1 - 1.6e-72 242.7 13.7 1.6e-72 242.7 9.5 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 EAU83009.1 - 6.4e-14 51.3 13.7 6.4e-14 51.3 9.5 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU83009.1 - 0.011 15.7 2.7 0.021 14.8 1.8 1.5 1 0 0 1 1 1 0 Toxin 7 CFEM PF05730.6 EAU83012.1 - 0.023 14.5 5.2 0.027 14.2 3.6 1.1 1 0 0 1 1 1 0 CFEM domain Peptidase_M43 PF05572.8 EAU83013.1 - 2.2e-18 66.2 0.0 5.2e-18 65.1 0.0 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EAU83013.1 - 3.5e-05 24.3 0.0 5.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU83013.1 - 5.6e-05 23.2 0.0 7.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU83013.1 - 7.5e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU83013.1 - 0.00071 19.1 0.0 0.0013 18.3 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EAU83013.1 - 0.0054 16.0 0.1 0.0099 15.2 0.1 1.4 1 1 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EAU83013.1 - 0.01 15.5 0.0 0.025 14.3 0.0 1.6 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 EAU83013.1 - 0.065 12.0 0.3 0.1 11.4 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Astacin PF01400.19 EAU83013.1 - 0.16 11.3 0.5 0.31 10.4 0.4 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) zf-MYND PF01753.13 EAU83015.1 - 8.2e-11 41.6 7.4 1.6e-10 40.6 5.1 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU83015.1 - 0.049 12.9 2.7 0.1 11.9 1.9 1.4 1 0 0 1 1 1 0 Life-span regulatory factor RNR_inhib PF08591.5 EAU83017.2 - 0.072 14.0 5.4 0.072 14.0 2.8 1.6 1 1 1 2 2 2 0 Ribonucleotide reductase inhibitor CorA PF01544.13 EAU83018.2 - 0.00064 18.8 0.2 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein FtsX PF02687.16 EAU83018.2 - 0.041 13.6 1.7 0.065 12.9 1.2 1.3 1 0 0 1 1 1 0 FtsX-like permease family Abhydrolase_9_N PF15420.1 EAU83019.1 - 0.028 14.1 0.6 0.044 13.5 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Ribosomal_L14e PF01929.12 EAU83020.2 - 3.9e-26 91.2 0.2 6e-26 90.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EAU83020.2 - 0.0002 20.9 0.3 0.00038 20.0 0.2 1.5 1 0 0 1 1 1 1 KOW motif ATP_bind_2 PF03668.10 EAU83021.2 - 8.6e-10 38.1 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family Mago-bind PF09282.5 EAU83021.2 - 0.014 14.9 1.7 0.028 13.9 1.2 1.4 1 0 0 1 1 1 0 Mago binding Tic22 PF04278.7 EAU83021.2 - 0.074 12.3 0.1 0.15 11.3 0.0 1.4 1 1 0 1 1 1 0 Tic22-like family DUF605 PF04652.11 EAU83021.2 - 0.27 10.5 17.2 0.33 10.3 12.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 EAU83021.2 - 0.74 9.2 9.1 0.91 8.9 6.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF872 PF05915.7 EAU83025.1 - 0.13 12.0 2.1 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) HPP PF04982.8 EAU83028.1 - 2.4e-39 133.8 5.3 3.9e-39 133.2 3.7 1.3 1 0 0 1 1 1 1 HPP family zf-MYND PF01753.13 EAU83029.2 - 1e-09 38.0 1.6 2.2e-09 37.0 1.1 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU83029.2 - 0.029 13.6 1.2 0.061 12.6 0.8 1.4 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 EAU83031.2 - 4.3e-10 39.2 8.5 9.1e-10 38.2 5.9 1.6 1 0 0 1 1 1 1 MYND finger RseC_MucC PF04246.7 EAU83032.2 - 0.42 10.1 3.1 0.44 10.1 0.1 2.5 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC RNA_lig_T4_1 PF09511.5 EAU83033.1 - 1.2e-76 257.0 0.0 1.9e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EAU83033.1 - 3.8e-23 82.1 0.0 2.8e-12 46.8 0.0 2.4 2 0 0 2 2 2 2 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EAU83033.1 - 5.7e-06 25.7 0.0 0.027 13.7 0.0 2.6 2 0 0 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 EAU83033.1 - 0.018 15.8 0.1 0.078 13.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EAU83033.1 - 0.039 13.3 0.1 0.077 12.3 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ycf1 PF05758.7 EAU83033.1 - 4.9 4.7 3.8 7.3 4.1 2.6 1.1 1 0 0 1 1 1 0 Ycf1 Peroxidase_2 PF01328.12 EAU83038.2 - 2.6e-16 59.1 3.4 2.3e-15 56.0 2.3 2.0 1 1 0 1 1 1 1 Peroxidase, family 2 zf-MYND PF01753.13 EAU83041.2 - 2.3e-18 65.7 39.2 6.1e-11 42.0 6.8 2.9 3 0 0 3 3 3 2 MYND finger Ecl1 PF12855.2 EAU83041.2 - 0.58 9.4 13.2 2.4 7.4 1.6 2.5 2 0 0 2 2 2 0 Life-span regulatory factor zf-Mss51 PF13824.1 EAU83041.2 - 9.3 6.2 16.8 8.4 6.3 4.4 3.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 HPP PF04982.8 EAU83042.2 - 1.3e-37 128.2 5.7 1.3e-37 128.2 3.9 1.6 2 0 0 2 2 2 1 HPP family FecCD PF01032.13 EAU83042.2 - 0.0095 14.8 4.1 0.089 11.6 2.2 2.0 2 0 0 2 2 2 1 FecCD transport family DUF1113 PF06541.6 EAU83042.2 - 0.43 10.3 4.7 0.2 11.4 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1113) Acyl_transf_3 PF01757.17 EAU83042.2 - 1.7 7.4 10.4 10 4.8 7.2 1.9 1 1 0 1 1 1 0 Acyltransferase family Transgly_assoc PF04226.8 EAU83042.2 - 2 8.5 7.2 3.3 7.8 0.1 3.1 3 0 0 3 3 3 0 Transglycosylase associated protein DUF3792 PF12670.2 EAU83042.2 - 2 8.2 6.1 0.79 9.6 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) EmrE PF13536.1 EAU83042.2 - 3.4 7.9 12.6 1.6 8.9 4.8 2.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter zf-MYND PF01753.13 EAU83043.1 - 1.3e-07 31.3 18.4 4.1e-07 29.7 12.7 1.9 1 1 0 1 1 1 1 MYND finger Peroxidase_2 PF01328.12 EAU83044.1 - 9.1e-17 60.6 0.7 4.6e-16 58.3 0.5 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 TPD PF14811.1 EAU83044.1 - 0.21 11.1 0.2 0.33 10.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif DUF2183 PF09949.4 EAU83045.2 - 1.5e-20 73.0 0.0 2.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) WD40 PF00400.27 EAU83049.2 - 2.6e-07 30.2 0.9 0.0029 17.4 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-C2H2_jaz PF12171.3 EAU83051.1 - 0.00035 20.6 0.2 0.00061 19.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU83051.1 - 0.0027 17.8 0.6 0.0046 17.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3505 PF12013.3 EAU83051.1 - 0.064 13.5 3.0 0.17 12.1 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 EAU83051.1 - 0.09 12.8 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Citrate_synt PF00285.16 EAU83052.2 - 7.9e-68 228.7 0.0 9.2e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DUF1748 PF08520.5 EAU83052.2 - 0.11 12.0 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) Prp18 PF02840.10 EAU83053.1 - 2e-58 196.3 0.1 2e-58 196.3 0.1 2.5 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EAU83053.1 - 8.1e-13 47.3 4.3 2.3e-12 45.9 3.0 1.9 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DUF1675 PF07897.6 EAU83053.1 - 4 7.2 13.2 7.9 6.2 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Rotamase_2 PF13145.1 EAU83053.1 - 9.7 6.8 12.9 19 5.9 1.3 2.7 2 1 0 2 2 2 0 PPIC-type PPIASE domain COX6B PF02297.12 EAU83054.2 - 2.7e-19 68.9 10.2 3.2e-19 68.7 7.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CNPase PF05881.7 EAU83054.2 - 0.14 11.5 0.5 0.16 11.3 0.3 1.1 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Oxidored_molyb PF00174.14 EAU83055.2 - 1.1e-54 184.3 0.0 1.7e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EAU83055.2 - 3.9e-21 75.0 1.0 7.9e-21 74.0 0.2 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Fn3-like PF14310.1 EAU83055.2 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III-like domain DUF1748 PF08520.5 EAU83056.2 - 4.9e-24 83.7 0.0 5.5e-24 83.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) zf-Tim10_DDP PF02953.10 EAU83058.2 - 9.8e-08 31.1 2.4 9.8e-08 31.1 1.6 2.2 2 0 0 2 2 2 1 Tim10/DDP family zinc finger DnaJ PF00226.26 EAU83059.2 - 5.5e-25 86.8 1.9 1.4e-24 85.6 1.2 1.9 2 0 0 2 2 2 1 DnaJ domain ROS_MUCR PF05443.6 EAU83059.2 - 0.08 12.7 0.2 0.08 12.7 0.2 3.1 4 1 0 4 4 4 0 ROS/MUCR transcriptional regulator protein Cyt-b5 PF00173.23 EAU83062.1 - 5e-18 64.6 0.0 8.2e-18 63.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ApoL PF05461.6 EAU83063.2 - 0.21 10.8 0.3 0.32 10.1 0.2 1.2 1 0 0 1 1 1 0 Apolipoprotein L DUF4519 PF15012.1 EAU83063.2 - 7.2 6.6 5.1 1 9.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) CRAL_TRIO PF00650.15 EAU83065.1 - 1.2e-25 89.8 0.0 2.1e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAU83065.1 - 2.9e-13 49.7 0.3 6.6e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF684 PF05075.9 EAU83065.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) Fungal_trans PF04082.13 EAU83066.2 - 9.4e-22 77.1 0.3 3.6e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain bZIP_1 PF00170.16 EAU83066.2 - 0.29 11.1 1.0 0.59 10.1 0.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor Zn_clus PF00172.13 EAU83066.2 - 1.2 9.1 7.4 2.6 8.0 5.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MMR_HSR1 PF01926.18 EAU83067.2 - 1.1e-07 31.8 0.1 2.7e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU83067.2 - 1.6e-06 27.4 0.1 1.6e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 AIG1 family Septin PF00735.13 EAU83067.2 - 0.00047 19.2 0.0 0.00047 19.2 0.0 2.1 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.18 EAU83067.2 - 0.00092 19.0 14.5 0.0072 16.1 0.1 3.6 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 EAU83067.2 - 0.0017 17.6 2.4 0.0019 17.4 0.0 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 EAU83067.2 - 0.0044 16.2 0.4 0.0044 16.2 0.3 2.0 2 1 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EAU83067.2 - 0.0072 15.8 0.1 0.0072 15.8 0.1 2.2 2 0 0 2 2 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EAU83067.2 - 0.014 14.2 0.0 0.014 14.2 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EAU83067.2 - 0.016 15.6 2.3 0.05 14.1 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EAU83067.2 - 0.019 13.8 0.4 0.019 13.8 0.3 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 EAU83067.2 - 0.052 13.1 1.8 0.095 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU83067.2 - 0.081 12.8 3.1 0.41 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain GBP PF02263.14 EAU83067.2 - 0.098 11.6 0.0 0.098 11.6 0.0 1.7 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain AAA_29 PF13555.1 EAU83067.2 - 0.099 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EAU83067.2 - 0.13 12.5 0.1 0.13 12.5 0.0 2.6 2 1 0 2 2 1 0 ABC transporter AAA_17 PF13207.1 EAU83067.2 - 0.17 12.6 0.1 0.17 12.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain HSP70 PF00012.15 EAU83067.2 - 0.31 8.8 12.2 0.45 8.3 8.4 1.1 1 0 0 1 1 1 0 Hsp70 protein cobW PF02492.14 EAU83067.2 - 0.88 8.9 3.4 0.52 9.7 0.3 2.0 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EAU83067.2 - 1 9.0 4.0 0.64 9.7 0.4 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B YlqD PF11068.3 EAU83067.2 - 1.7 8.6 27.5 0.33 10.9 8.1 2.2 1 1 1 2 2 2 0 YlqD protein Amidase PF01425.16 EAU83067.2 - 5.3 5.7 8.6 11 4.7 5.5 1.7 1 1 1 2 2 2 0 Amidase AAA_22 PF13401.1 EAU83067.2 - 5.4 7.1 7.6 0.96 9.5 0.1 2.9 3 1 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 EAU83067.2 - 5.8 6.3 9.1 0.97 8.9 0.7 3.0 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein OmpH PF03938.9 EAU83067.2 - 5.9 6.8 32.5 2.4e+03 -1.7 22.5 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Borrelia_P83 PF05262.6 EAU83067.2 - 8.8 4.4 15.4 13 3.8 10.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.14 EAU83067.2 - 9.6 3.9 9.0 13 3.4 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CTDII PF01556.13 EAU83068.2 - 8.9e-05 22.3 0.0 0.0017 18.1 0.0 2.4 2 1 0 2 2 2 1 DnaJ C terminal domain F-box-like PF12937.2 EAU83069.1 - 2.8e-07 30.1 0.1 0.00017 21.2 0.0 2.5 2 0 0 2 2 2 2 F-box-like UbiA PF01040.13 EAU83070.2 - 1.9e-27 96.1 21.4 2.7e-27 95.6 14.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RRM_1 PF00076.17 EAU83071.1 - 1.1e-18 66.6 0.0 1.8e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU83071.1 - 1.5e-17 63.2 0.0 2.4e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 EAU83071.1 - 3.1e-17 62.6 7.4 7.3e-17 61.4 5.1 1.6 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 EAU83071.1 - 1.8e-10 40.4 0.0 1e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox PF00046.24 EAU83072.2 - 2.9e-17 62.0 3.2 6.2e-17 60.9 2.2 1.6 1 0 0 1 1 1 1 Homeobox domain TPR_3 PF07720.7 EAU83072.2 - 0.28 11.0 2.6 1 9.2 1.8 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TEA PF01285.13 EAU83076.1 - 1.9e-15 56.9 0.0 1.9e-15 56.9 0.0 1.5 2 0 0 2 2 2 1 TEA/ATTS domain family Zip PF02535.17 EAU83077.2 - 8.9e-45 153.0 13.0 2.9e-44 151.3 9.0 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Peptidase_C15 PF01470.12 EAU83078.2 - 1.5e-20 73.8 0.0 1.3e-13 51.2 0.0 2.1 1 1 0 2 2 2 2 Pyroglutamyl peptidase DUF976 PF06162.7 EAU83078.2 - 0.017 14.6 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF976) HD PF01966.17 EAU83079.1 - 3.5e-07 30.2 0.2 7.3e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 HD domain DNA_pol3_delta2 PF13177.1 EAU83080.2 - 7e-14 51.7 0.1 1.8e-13 50.4 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EAU83080.2 - 5.2e-11 42.3 0.0 1.7e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.8 EAU83080.2 - 1.6e-06 27.7 0.2 2.4e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EAU83080.2 - 2.9e-06 27.5 0.7 6.3e-06 26.4 0.5 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU83080.2 - 0.0025 17.9 1.1 0.012 15.7 0.8 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU83080.2 - 0.0041 17.1 0.2 0.095 12.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EAU83080.2 - 0.0046 16.4 0.4 0.08 12.3 0.0 2.1 1 1 0 2 2 2 1 AAA-like domain Lipoprotein_18 PF06804.6 EAU83080.2 - 0.013 14.2 0.4 0.022 13.4 0.3 1.3 1 0 0 1 1 1 0 NlpB/DapX lipoprotein AAA_33 PF13671.1 EAU83080.2 - 0.016 15.0 0.2 0.039 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EAU83080.2 - 0.022 13.8 0.1 6.7 5.6 0.0 2.6 2 1 1 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAU83080.2 - 0.024 14.3 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EAU83080.2 - 0.026 14.5 0.4 0.072 13.1 0.3 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain SNF2_N PF00176.18 EAU83080.2 - 0.03 13.0 0.1 0.042 12.6 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Bac_DnaA PF00308.13 EAU83080.2 - 0.041 13.5 1.4 1.1 8.8 0.1 2.9 2 1 1 3 3 3 0 Bacterial dnaA protein DUF968 PF06147.6 EAU83080.2 - 0.053 13.4 0.3 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF968) DEAD PF00270.24 EAU83080.2 - 0.13 11.7 0.5 0.21 11.0 0.3 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF3802 PF12290.3 EAU83080.2 - 0.16 12.2 1.8 0.18 12.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Alk_phosphatase PF00245.15 EAU83081.2 - 6e-68 229.4 0.3 1.9e-67 227.8 0.2 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 EAU83081.2 - 8.2e-07 28.6 1.7 1.9e-06 27.4 1.1 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAU83081.2 - 4.4e-06 26.0 0.8 1.7e-05 24.1 0.5 2.2 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EAU83081.2 - 0.0083 14.5 0.2 0.012 14.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EAU83081.2 - 0.17 11.2 2.9 0.53 9.6 0.3 2.5 3 0 0 3 3 3 0 Metalloenzyme superfamily Bud13 PF09736.4 EAU83082.2 - 8.6e-47 159.0 9.8 8.6e-47 159.0 6.8 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex CASP_C PF08172.7 EAU83083.2 - 0.024 13.6 0.1 0.04 12.9 0.1 1.2 1 0 0 1 1 1 0 CASP C terminal CorA PF01544.13 EAU83083.2 - 0.17 10.9 7.9 0.56 9.1 2.0 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 EAU83084.2 - 2.9e-13 49.2 21.4 2.9e-13 49.2 14.8 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EAU83086.2 - 1.2e-26 93.2 0.1 4e-25 88.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU83086.2 - 2e-08 34.0 9.3 3.4e-08 33.2 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COQ9 PF08511.6 EAU83087.2 - 4.8e-11 42.0 0.0 1.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 COQ9 2Fe-2S_thioredx PF01257.14 EAU83087.2 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin eIF3_subunit PF08597.5 EAU83088.1 - 8.9e-50 169.5 19.1 1e-49 169.3 13.2 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3347 PF11827.3 EAU83088.1 - 6.7 6.6 8.8 2.5 8.0 2.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) HLH PF00010.21 EAU83089.1 - 6.9e-06 25.6 0.4 2.1e-05 24.1 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAT1 PF09770.4 EAU83089.1 - 0.77 7.9 46.6 1.1 7.4 32.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 EAU83091.1 - 1.6e-08 34.0 0.1 0.0017 18.0 0.0 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EAU83091.1 - 1.6 8.5 4.7 31 4.3 0.0 3.4 4 0 0 4 4 4 0 F-box domain PH_7 PF15408.1 EAU83092.1 - 0.088 12.6 0.1 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2384 PF09722.5 EAU83092.1 - 0.14 12.0 1.2 0.26 11.1 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2384) Cu_amine_oxid PF01179.15 EAU83093.2 - 2.8e-108 362.2 7.6 4.6e-108 361.5 5.3 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EAU83093.2 - 3.7e-21 74.8 0.0 9e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EAU83093.2 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Fungal_trans PF04082.13 EAU83094.2 - 8.4e-31 106.7 0.0 1.4e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU83094.2 - 4.5e-06 26.4 12.3 8.1e-06 25.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Whi5 PF08528.6 EAU83097.2 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Whi5 like HIT PF01230.18 EAU83098.1 - 1.4e-24 86.5 0.2 1.9e-24 86.0 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EAU83098.1 - 7.3e-13 48.7 0.2 9.8e-13 48.3 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EAU83098.1 - 1.2e-05 24.9 0.7 2e-05 24.2 0.5 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Enterotoxin_HS1 PF08090.6 EAU83098.1 - 0.068 12.9 0.4 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 Heat stable E.coli enterotoxin 1 Strep_his_triad PF04270.8 EAU83098.1 - 0.21 11.3 0.7 7.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Streptococcal histidine triad protein SUR7 PF06687.7 EAU83099.2 - 0.00054 19.5 0.5 0.00059 19.4 0.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Metallophos PF00149.23 EAU83101.1 - 1.1e-07 31.4 3.4 2.7e-07 30.1 2.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU83101.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 EAU83101.1 - 0.071 11.1 0.0 0.13 10.2 0.0 1.3 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase ACPS PF01648.15 EAU83102.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ECH PF00378.15 EAU83103.1 - 2.1e-27 95.8 0.0 2.7e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 EAU83105.1 - 1.6e-58 197.9 0.2 2.5e-57 193.9 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU83105.1 - 2.7e-32 111.8 0.0 1.5e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EAU83105.1 - 8.4e-07 28.9 0.4 0.00014 21.6 0.1 2.7 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EAU83105.1 - 0.00028 20.0 0.0 0.0006 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU83105.1 - 0.00091 18.2 0.0 0.049 12.5 0.0 2.4 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EAU83105.1 - 0.00094 18.5 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EAU83105.1 - 0.0071 15.7 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL PEX11 PF05648.9 EAU83106.1 - 3.8e-15 55.7 0.3 1.2e-13 50.8 0.2 2.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HMG_box PF00505.14 EAU83107.2 - 1e-07 32.0 0.1 2.1e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU83107.2 - 5.9e-07 29.7 0.2 1.4e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain NAD_binding_10 PF13460.1 EAU83108.1 - 1.5e-12 47.9 0.1 9.1e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EAU83108.1 - 9.6e-11 41.3 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EAU83108.1 - 6.6e-07 28.9 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAU83108.1 - 1.2e-06 27.4 0.0 1.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU83108.1 - 3.1e-06 26.3 0.0 5.3e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 EAU83108.1 - 2.3e-05 24.6 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAU83108.1 - 5e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EAU83108.1 - 0.0026 16.8 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EAU83108.1 - 0.0075 16.1 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EAU83108.1 - 0.0097 15.8 0.0 0.28 11.1 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.12 EAU83108.1 - 0.01 16.2 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EAU83108.1 - 0.032 13.9 0.1 2.7 7.6 0.0 2.3 1 1 1 2 2 2 0 KR domain NmrA PF05368.8 EAU83109.1 - 9.8e-10 38.0 0.1 2e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAU83109.1 - 2.9e-08 33.9 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EAU83109.1 - 2e-06 27.0 0.0 2.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EAU83109.1 - 5.8e-05 22.1 0.1 8.2e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EAU83109.1 - 6.5e-05 22.4 0.0 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAU83109.1 - 7.3e-05 21.6 0.0 0.0001 21.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EAU83109.1 - 0.00012 22.0 0.1 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 EAU83109.1 - 0.003 17.2 0.5 0.45 10.1 0.6 2.2 1 1 1 2 2 2 2 KR domain Semialdhyde_dh PF01118.19 EAU83109.1 - 0.0052 17.0 0.0 0.0085 16.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EAU83109.1 - 0.0061 16.4 0.6 0.023 14.5 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.15 EAU83109.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.11 EAU83109.1 - 0.098 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ribosomal_L4 PF00573.17 EAU83110.1 - 2.6e-43 147.6 2.2 3.8e-43 147.1 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EAU83110.1 - 1.3e-29 101.8 8.6 2.6e-29 100.9 3.0 2.6 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PARP PF00644.15 EAU83112.2 - 4.9e-15 55.5 2.2 7.9e-12 45.0 1.5 3.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.9 EAU83112.2 - 0.027 14.1 3.4 0.027 14.1 2.3 4.7 5 1 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif DUF329 PF03884.9 EAU83112.2 - 0.081 12.4 18.6 0.049 13.1 1.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF329) Mito_fiss_reg PF05308.6 EAU83112.2 - 0.44 9.8 5.4 0.82 8.9 3.7 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Metallothio_Pro PF02069.11 EAU83112.2 - 3.5 7.5 28.3 1.7 8.5 0.9 5.1 3 1 1 4 4 4 0 Prokaryotic metallothionein PARP PF00644.15 EAU83113.2 - 0.033 13.6 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 EAU83114.1 - 1.3e-17 63.9 0.2 7.4e-10 38.5 0.2 3.0 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 EAU83115.2 - 1.1e-20 74.0 0.1 1.9e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PHF5 PF03660.9 EAU83116.1 - 0.61 10.1 10.7 2.7 8.0 1.7 2.4 2 0 0 2 2 2 0 PHF5-like protein PAT1 PF09770.4 EAU83116.1 - 0.68 8.0 24.8 0.85 7.7 17.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF581 PF04570.9 EAU83116.1 - 2.6 7.4 9.6 2.6 7.4 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF581) RPAP2_Rtr1 PF04181.8 EAU83116.1 - 6.6 6.8 19.7 9.5 6.3 0.4 3.9 3 1 1 4 4 4 0 Rtr1/RPAP2 family zf-MYND PF01753.13 EAU83116.1 - 9.2 6.2 27.6 7.7 6.4 2.9 4.4 2 2 0 2 2 2 0 MYND finger Coq4 PF05019.8 EAU83118.2 - 3.2e-95 317.2 0.0 4e-95 316.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 YibE_F PF07907.6 EAU83119.2 - 0.0016 17.6 0.2 0.0016 17.6 0.1 1.7 2 0 0 2 2 2 1 YibE/F-like protein PLDc_2 PF13091.1 EAU83121.2 - 1.9e-12 47.0 0.0 7.4e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EAU83121.2 - 1.6e-06 27.7 0.4 0.013 15.3 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Kdo_hydroxy PF11004.3 EAU83122.1 - 0.13 11.2 0.0 0.46 9.4 0.0 1.7 2 0 0 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase F-box-like PF12937.2 EAU83123.1 - 5e-07 29.3 0.0 2.1e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EAU83123.1 - 0.0011 18.5 1.5 0.36 10.5 0.0 3.1 3 0 0 3 3 3 2 F-box domain THOC7 PF05615.8 EAU83123.1 - 0.077 13.2 4.4 0.16 12.2 3.1 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 HAUS6_N PF14661.1 EAU83123.1 - 0.1 11.9 2.8 0.18 11.0 1.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.8 EAU83123.1 - 0.19 10.1 3.1 0.26 9.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Thg1 PF04446.7 EAU83124.1 - 1.5 8.4 4.2 7.3 6.2 0.1 2.5 2 1 1 3 3 3 0 tRNAHis guanylyltransferase p450 PF00067.17 EAU83133.2 - 7.7e-10 37.8 1.0 0.0056 15.2 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 Nop14 PF04147.7 EAU83134.2 - 0.0076 14.2 4.3 0.011 13.6 3.0 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EAU83134.2 - 0.19 9.7 4.1 0.32 8.9 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EAU83134.2 - 0.76 9.3 9.4 1.6 8.3 4.8 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region p450 PF00067.17 EAU83136.2 - 2e-61 207.9 0.0 3.4e-61 207.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EAU83138.2 - 7.1e-14 51.4 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU83138.2 - 5.9e-12 45.3 0.0 9.5e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EAU83138.2 - 0.00012 22.9 0.0 0.00031 21.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Lactonase PF10282.4 EAU83139.2 - 2.2e-33 115.7 0.0 2.9e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller UPF0014 PF03649.8 EAU83140.2 - 1e-33 116.5 14.5 6.9e-23 81.0 2.6 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0014) FtsX PF02687.16 EAU83140.2 - 0.0033 17.1 0.0 0.0033 17.1 0.0 4.1 3 1 1 4 4 4 2 FtsX-like permease family zf-CCCH PF00642.19 EAU83147.2 - 4.4e-06 26.2 0.7 4.4e-06 26.2 0.5 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) F-box-like PF12937.2 EAU83147.2 - 0.005 16.5 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-CCCH_2 PF14608.1 EAU83147.2 - 2.4 8.3 9.4 15 5.7 0.2 2.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type RRM_1 PF00076.17 EAU83148.1 - 3.1e-07 29.9 0.0 5.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU83148.1 - 1.4e-06 28.0 0.0 3.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU83148.1 - 1.3e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU83148.1 - 1.6e-05 24.5 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2775 PF10950.3 EAU83150.1 - 0.075 13.2 0.2 0.075 13.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2775) Effector_1 PF04518.7 EAU83152.2 - 0.082 11.8 0.0 0.099 11.6 0.0 1.0 1 0 0 1 1 1 0 Effector from type III secretion system ABC_membrane PF00664.18 EAU83155.1 - 1.3e-34 119.8 12.0 1.6e-34 119.5 8.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EAU83155.1 - 4.7e-34 117.6 0.0 1e-33 116.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EAU83155.1 - 3.8e-07 29.5 1.6 0.0011 18.2 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU83155.1 - 2.5e-06 27.6 0.1 0.029 14.3 0.0 2.6 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EAU83155.1 - 0.00027 21.1 0.1 0.0032 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU83155.1 - 0.00097 19.1 0.0 0.004 17.1 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EAU83155.1 - 0.0017 18.2 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU83155.1 - 0.002 18.9 0.0 0.006 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAU83155.1 - 0.0035 16.8 0.0 0.012 15.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EAU83155.1 - 0.0058 16.8 0.1 0.073 13.2 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EAU83155.1 - 0.0097 15.1 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EAU83155.1 - 0.013 14.1 0.1 0.032 12.8 0.1 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 EAU83155.1 - 0.016 15.5 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU83155.1 - 0.023 14.5 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EAU83155.1 - 0.028 14.1 0.0 0.11 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EAU83155.1 - 0.045 13.7 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EAU83155.1 - 0.05 13.5 1.5 0.22 11.4 0.3 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EAU83155.1 - 0.063 13.5 0.0 0.5 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EAU83155.1 - 0.091 12.7 0.2 0.51 10.2 0.0 2.4 2 1 1 3 3 3 0 AAA domain Rad17 PF03215.10 EAU83155.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2586 PF10758.4 EAU83156.2 - 2.1 7.2 6.7 3 6.7 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) Lipase_GDSL_3 PF14606.1 EAU83156.2 - 8.4 6.0 8.0 4.7 6.8 3.7 1.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2415 PF10313.4 EAU83158.1 - 1.2e-06 28.0 0.0 7.4e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Nucleoplasmin PF03066.10 EAU83158.1 - 0.11 11.9 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin WD40 PF00400.27 EAU83158.1 - 0.17 11.8 7.6 3 7.8 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat NACHT PF05729.7 EAU83162.2 - 1.8e-09 37.4 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU83162.2 - 0.00022 21.3 0.0 0.0023 18.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU83162.2 - 0.00081 19.4 0.2 0.0029 17.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EAU83162.2 - 0.082 13.1 0.0 0.2 11.8 0.0 1.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRP38_assoc PF12871.2 EAU83164.2 - 6.4e-06 26.6 30.4 4.9e-05 23.7 11.5 11.7 7 3 1 9 9 9 2 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Atrophin-1 PF03154.10 EAU83164.2 - 0.0014 16.9 2.1 0.0014 16.9 1.5 11.1 6 3 3 9 9 9 1 Atrophin-1 family DUF641 PF04859.7 EAU83164.2 - 3.3 7.4 21.5 0.62 9.8 1.7 3.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) OmpH PF03938.9 EAU83164.2 - 7.5 6.4 30.2 0.18 11.7 7.1 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) F-box-like PF12937.2 EAU83167.2 - 0.0028 17.3 0.1 0.0081 15.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like DUF2415 PF10313.4 EAU83170.2 - 1.2e-08 34.5 0.0 4.1e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) TFIIA PF03153.8 EAU83170.2 - 6.2 6.6 14.3 0.38 10.5 2.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zn_Tnp_IS91 PF14319.1 EAU83172.1 - 1.8 8.0 7.7 9.4 5.7 2.2 2.3 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.1 EAU83172.1 - 7.6 6.3 8.6 6.7 6.5 0.1 3.0 3 1 0 3 3 3 0 zinc-RING finger domain HMG_box PF00505.14 EAU83173.1 - 1.4e-07 31.6 0.6 0.00014 22.0 0.0 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box Ferritin_2 PF13668.1 EAU83174.1 - 2.3e-18 66.4 0.1 3.3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF900 PF05990.7 EAU83174.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) HMG_box PF00505.14 EAU83176.1 - 4.1e-10 39.7 0.4 7.5e-10 38.9 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU83176.1 - 4.8e-06 26.8 0.1 1.4e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EAU83177.2 - 4.4e-07 30.0 0.1 8.6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EAU83177.2 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box_2 PF09011.5 EAU83177.2 - 0.011 16.0 0.1 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain DUF4553 PF15090.1 EAU83177.2 - 0.21 10.5 3.6 0.29 10.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) DUF605 PF04652.11 EAU83177.2 - 7.6 5.8 12.9 9.5 5.5 8.9 1.1 1 0 0 1 1 1 0 Vta1 like DSPc PF00782.15 EAU83178.2 - 2.8e-24 85.1 0.0 1.1e-21 76.8 0.0 3.3 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAU83178.2 - 0.013 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Phage_connect_1 PF05135.8 EAU83178.2 - 0.48 10.6 4.1 0.35 11.0 0.0 2.6 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein GMC_oxred_N PF00732.14 EAU83180.1 - 6.4e-61 206.0 0.0 8.8e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU83180.1 - 1.5e-33 116.1 0.0 2.5e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EAU83180.1 - 2.1e-06 26.9 0.2 3.2e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EAU83180.1 - 0.00037 19.5 2.0 0.0018 17.2 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU83180.1 - 0.00092 19.1 0.6 0.0043 17.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU83180.1 - 0.0054 16.6 0.2 0.072 12.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU83180.1 - 0.023 13.5 1.0 0.049 12.4 0.7 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EAU83180.1 - 0.034 12.6 0.3 0.062 11.7 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EAU83180.1 - 0.087 11.9 0.3 0.2 10.6 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EAU83180.1 - 0.097 12.7 0.0 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF427 PF04248.7 EAU83182.1 - 5.9e-10 38.6 1.0 6.7e-10 38.4 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DUF202 PF02656.10 EAU83183.1 - 2e-09 37.5 1.8 2e-09 37.5 1.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF4401 PF14351.1 EAU83183.1 - 0.0027 16.7 0.3 0.0037 16.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DnaJ PF00226.26 EAU83184.1 - 6.5e-28 96.2 1.8 1.2e-27 95.4 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EAU83184.1 - 6.9e-17 61.1 1.8 4.9e-14 51.9 0.2 2.8 2 1 0 2 2 2 2 DnaJ C terminal domain F_actin_cap_B PF01115.12 EAU83187.1 - 1.8e-99 331.8 0.0 2.8e-99 331.2 0.0 1.3 1 1 0 1 1 1 1 F-actin capping protein, beta subunit Pro_isomerase PF00160.16 EAU83188.2 - 6.1e-50 169.4 0.1 6.9e-50 169.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BtpA PF03437.10 EAU83188.2 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 BtpA family G-alpha PF00503.15 EAU83189.1 - 1.2e-114 383.1 0.0 1.4e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU83189.1 - 1.7e-14 53.4 0.1 2.2e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 EAU83189.1 - 5.2e-05 22.6 0.0 0.0079 15.5 0.0 2.3 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 EAU83189.1 - 0.0013 17.8 0.1 0.61 9.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EAU83189.1 - 0.012 15.1 0.1 0.053 13.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EAU83189.1 - 0.055 12.8 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EAU83189.1 - 0.082 13.4 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Stomoxyn PF11585.3 EAU83191.1 - 0.072 12.8 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn MscS_porin PF12795.2 EAU83191.1 - 0.74 9.0 27.2 0.16 11.3 2.1 3.3 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain HlyD PF00529.15 EAU83191.1 - 0.77 9.0 13.2 1.3 8.2 9.1 1.4 1 0 0 1 1 1 0 HlyD family secretion protein GNVR PF13807.1 EAU83191.1 - 4.7 7.0 12.5 3.3 7.5 0.4 2.7 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Aminotran_1_2 PF00155.16 EAU83192.1 - 4.8e-15 55.3 0.0 7e-08 31.7 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Pkinase PF00069.20 EAU83193.2 - 8.5e-46 156.1 0.0 1.7e-45 155.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU83193.2 - 4.3e-24 85.0 0.0 2.1e-19 69.6 0.0 3.2 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EAU83193.2 - 0.00029 19.8 0.0 0.24 10.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EAU83193.2 - 0.00064 19.5 0.2 0.11 12.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Zip PF02535.17 EAU83193.2 - 0.62 9.0 1.2 0.93 8.4 0.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter MAT_Alpha1 PF04769.7 EAU83194.2 - 3.1e-08 33.2 0.1 6.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG_box PF00505.14 EAU83194.2 - 6.6e-08 32.7 2.5 7.9e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU83194.2 - 4.2e-06 27.0 0.1 9.4e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain DUF1771 PF08590.5 EAU83194.2 - 0.014 15.3 1.9 0.034 14.1 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) MRC1 PF09444.5 EAU83194.2 - 0.021 15.1 0.3 0.021 15.1 0.2 2.2 2 0 0 2 2 2 0 MRC1-like domain DUF1074 PF06382.6 EAU83194.2 - 0.026 14.4 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1074) Epimerase PF01370.16 EAU83195.2 - 1.4e-05 24.7 0.0 0.0063 15.9 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAU83195.2 - 5.7e-05 21.9 0.0 9.6e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EAU83195.2 - 9e-05 21.6 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EAU83195.2 - 0.00031 20.0 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EAU83195.2 - 0.00045 20.2 0.0 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain Semialdhyde_dh PF01118.19 EAU83195.2 - 0.0009 19.5 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EAU83195.2 - 0.0037 17.3 0.0 0.0073 16.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EAU83195.2 - 0.025 13.5 0.0 0.053 12.4 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein adh_short PF00106.20 EAU83195.2 - 0.14 12.0 0.4 5.4 6.8 0.1 2.5 1 1 1 2 2 2 0 short chain dehydrogenase FlaC_arch PF05377.6 EAU83197.2 - 0.099 12.5 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 EAU83197.2 - 0.11 12.9 0.2 22 5.5 0.0 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.1 EAU83197.2 - 0.15 12.1 0.0 15 5.7 0.0 2.9 2 1 1 3 3 3 0 Syntaxin-like protein p450 PF00067.17 EAU83198.2 - 6.2e-62 209.6 0.0 7.8e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WHG PF13305.1 EAU83198.2 - 0.01 16.4 0.0 0.038 14.5 0.0 2.0 2 0 0 2 2 2 1 WHG domain DUF427 PF04248.7 EAU83200.1 - 5.9e-31 105.9 0.0 6e-25 86.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) Glyco_transf_22 PF03901.12 EAU83201.2 - 8e-40 137.1 24.1 1.1e-39 136.6 16.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_61 PF03443.9 EAU83203.1 - 2.3e-59 200.8 0.0 2.6e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ala_racemase_N PF01168.15 EAU83204.2 - 1.9e-38 132.1 0.0 3.7e-38 131.2 0.0 1.4 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain p450 PF00067.17 EAU83206.2 - 1.1e-49 169.2 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CDC45 PF02724.9 EAU83207.2 - 1.3 6.9 12.8 1.8 6.5 8.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EAU83207.2 - 4.5 5.0 19.3 6.6 4.5 13.4 1.1 1 0 0 1 1 1 0 Nop14-like family p450 PF00067.17 EAU83212.2 - 2.8e-07 29.4 0.0 3.6e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.1 EAU83213.1 - 1.3e-07 31.4 0.0 3.5e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease IncA PF04156.9 EAU83218.2 - 0.00071 19.2 3.0 0.00071 19.2 2.1 1.8 2 0 0 2 2 1 1 IncA protein AAA_13 PF13166.1 EAU83218.2 - 0.037 12.5 0.7 0.053 11.9 0.5 1.1 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EAU83218.2 - 0.042 13.9 4.9 0.1 12.7 3.4 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KLRAQ PF10205.4 EAU83218.2 - 0.074 13.0 4.1 0.19 11.8 2.8 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein GAS PF13851.1 EAU83218.2 - 0.097 11.8 6.2 0.17 11.0 4.3 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EAU83218.2 - 0.1 12.4 11.2 0.59 9.9 1.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 EAU83218.2 - 0.13 11.6 6.9 0.23 10.8 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) bZIP_2 PF07716.10 EAU83218.2 - 0.14 12.0 1.4 0.31 10.8 0.9 1.7 1 0 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.14 EAU83218.2 - 0.22 9.3 2.0 0.3 8.8 1.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 EAU83218.2 - 0.32 10.5 4.2 0.62 9.5 2.9 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlgN PF05130.7 EAU83218.2 - 0.42 10.8 9.0 0.12 12.6 4.0 1.7 2 0 0 2 2 1 0 FlgN protein GA PF01468.12 EAU83218.2 - 0.43 10.7 3.0 4.8 7.3 0.1 2.8 2 0 0 2 2 2 0 GA module DUF342 PF03961.8 EAU83218.2 - 0.69 8.2 3.8 1.1 7.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EAU83218.2 - 0.97 8.4 7.5 1.6 7.7 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EAU83218.2 - 1.1 7.9 10.1 0.4 9.3 3.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Spc24 PF08286.6 EAU83218.2 - 3.8 7.2 13.1 0.22 11.2 0.7 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 YlqD PF11068.3 EAU83218.2 - 5.4 7.0 8.3 11 6.1 1.4 2.2 1 1 1 2 2 2 0 YlqD protein DUF2890 PF11081.3 EAU83219.2 - 3.6 7.6 12.8 0.11 12.6 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Ta0938 PF11494.3 EAU83220.2 - 0.14 12.3 1.7 0.58 10.3 1.2 2.1 1 0 0 1 1 1 0 Ta0938 Phe_tRNA-synt_N PF02912.13 EAU83223.2 - 0.086 12.5 0.1 9 6.1 0.1 2.6 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Ead_Ea22 PF13935.1 EAU83223.2 - 7.9 6.8 9.5 6.1 7.1 1.2 2.8 3 0 0 3 3 3 0 Ead/Ea22-like protein Fungal_trans PF04082.13 EAU83233.2 - 2e-24 85.8 0.1 4.9e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU83233.2 - 0.035 13.9 7.4 0.03 14.2 2.6 2.4 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.9 EAU83233.2 - 1.9 7.8 12.8 3.5 6.9 8.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Polysacc_deac_1 PF01522.16 EAU83234.2 - 1.6e-26 92.3 0.1 2.8e-26 91.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Vps16_N PF04841.8 EAU83234.2 - 0.047 12.2 0.0 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 Vps16, N-terminal region DUF3669 PF12417.3 EAU83235.1 - 0.064 12.9 0.1 0.51 10.0 0.1 2.1 2 0 0 2 2 2 0 Zinc finger protein Ion_trans PF00520.26 EAU83235.1 - 0.067 12.4 0.4 0.1 11.8 0.3 1.3 1 0 0 1 1 1 0 Ion transport protein GST_N PF02798.15 EAU83236.1 - 1.9e-21 75.9 0.0 3.4e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAU83236.1 - 4.1e-19 68.5 0.0 6.9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU83236.1 - 9.7e-15 54.3 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EAU83236.1 - 1.5e-13 50.5 0.0 2.8e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU83236.1 - 5.6e-07 29.3 0.2 1.4e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU83236.1 - 1.5e-05 25.3 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.21 EAU83237.1 - 4.3e-13 48.9 0.0 9.8e-13 47.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU83237.1 - 5.2e-12 45.4 0.1 9.7e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EAU83237.1 - 0.0086 16.0 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding SMP PF04927.7 EAU83237.1 - 0.027 14.4 0.1 0.06 13.3 0.1 1.5 1 0 0 1 1 1 0 Seed maturation protein DUF3263 PF11662.3 EAU83244.1 - 0.12 11.8 0.1 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) Mto2_bdg PF12808.2 EAU83245.1 - 0.054 13.6 0.7 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.10 EAU83245.1 - 0.12 11.8 0.2 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator ORC5_C PF14630.1 EAU83247.1 - 0.16 11.4 1.9 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Nucleo_P87 PF07267.6 EAU83248.1 - 3.7 6.1 16.1 0.043 12.5 5.8 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 DDE_Tnp_4 PF13359.1 EAU83249.2 - 5.3e-29 100.8 0.0 7.3e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 EAU83249.2 - 5.4e-20 71.6 0.0 1.2e-19 70.4 0.0 1.5 2 0 0 2 2 2 1 Plant transposon protein DDE_Tnp_1 PF01609.16 EAU83249.2 - 2.8e-06 27.0 0.2 7.1e-05 22.4 0.1 2.2 1 1 0 1 1 1 1 Transposase DDE domain zf-H2C2_2 PF13465.1 EAU83250.2 - 0.00021 21.4 11.0 0.007 16.6 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU83250.2 - 0.073 13.4 9.3 1.2 9.6 1.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger ADH_N PF08240.7 EAU83251.2 - 8.7e-12 44.7 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU83251.2 - 2.4e-11 43.3 0.0 3.7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU83252.2 - 3.6e-13 49.2 0.1 5.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU83252.2 - 3.9e-11 42.5 0.0 6.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GST_C PF00043.20 EAU83254.2 - 1.5e-13 50.4 0.1 2e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU83254.2 - 3.5e-09 36.4 0.0 6.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU83254.2 - 2.8e-05 24.5 0.1 6.4e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Vir_act_alpha_C PF10400.4 EAU83254.2 - 0.098 13.0 0.1 0.41 11.0 0.0 2.0 2 0 0 2 2 2 0 Virulence activator alpha C-term XRN_N PF03159.13 EAU83256.2 - 5e-90 301.0 0.0 8.6e-90 300.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus LexA_DNA_bind PF01726.11 EAU83256.2 - 0.021 14.3 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 LexA DNA binding domain GMP_synt_C PF00958.17 EAU83257.2 - 5.8e-41 138.1 0.1 1.3e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EAU83257.2 - 8.5e-35 119.9 0.0 1.6e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EAU83257.2 - 2.5e-10 39.6 0.1 1.6e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EAU83257.2 - 7.5e-09 35.3 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 EAU83257.2 - 0.00086 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EAU83257.2 - 0.00087 18.8 0.0 0.0019 17.7 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase tRNA_Me_trans PF03054.11 EAU83257.2 - 0.0012 17.4 0.1 0.0021 16.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 EAU83257.2 - 0.0048 16.2 0.0 0.016 14.4 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EAU83257.2 - 0.0085 15.1 0.1 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Arginosuccinate synthase ATP_bind_3 PF01171.15 EAU83257.2 - 0.022 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 PP-loop family PAPS_reduct PF01507.14 EAU83257.2 - 0.075 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 EAU83257.2 - 0.16 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) Myb_DNA-binding PF00249.26 EAU83258.1 - 1.5e-34 117.8 7.1 2.9e-12 46.4 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAU83258.1 - 9.7e-29 99.2 1.2 2.6e-14 53.0 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EAU83258.1 - 0.0077 16.1 2.0 1.6 8.7 0.9 3.7 4 0 0 4 4 4 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EAU83258.1 - 0.016 15.3 3.8 1.9 8.7 0.2 3.7 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.6 EAU83258.1 - 0.017 14.8 0.4 3.7 7.4 0.0 2.9 2 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.1 EAU83258.1 - 0.025 14.7 7.5 0.12 12.5 0.9 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF1190 PF06693.6 EAU83258.1 - 0.027 14.5 0.1 0.069 13.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) Rap1_C PF11626.3 EAU83258.1 - 0.029 14.2 6.1 5.1 7.0 0.2 3.3 1 1 1 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Aldose_epim PF01263.15 EAU83259.1 - 2.3e-22 79.4 0.0 4.8e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 Aldose 1-epimerase Polysacc_deac_1 PF01522.16 EAU83261.2 - 1.9e-22 79.1 0.0 4.2e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Endonuclease_NS PF01223.18 EAU83261.2 - 0.058 13.0 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Fungal_trans PF04082.13 EAU83262.2 - 1.5e-25 89.5 0.1 5.7e-25 87.6 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU83262.2 - 0.021 14.7 0.2 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EAU83262.2 - 0.096 12.6 0.6 0.22 11.4 0.4 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain CCDC32 PF14989.1 EAU83262.2 - 0.1 12.4 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing 32 zf-CCHC PF00098.18 EAU83263.2 - 0.0092 15.8 1.2 0.018 14.9 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RGS-like PF09128.6 EAU83263.2 - 0.087 12.3 3.2 0.54 9.7 0.2 2.3 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Anti-adapt_IraP PF10796.4 EAU83263.2 - 3.8 7.9 6.3 17 5.8 0.0 3.0 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein RbsD_FucU PF05025.8 EAU83264.1 - 0.068 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family p450 PF00067.17 EAU83265.2 - 9.4e-58 195.8 0.0 2.6e-50 171.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EAU83268.1 - 3.8e-78 263.0 0.0 4.8e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S30 PF01577.11 EAU83274.1 - 0.03 13.7 4.0 0.052 12.9 2.8 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease AAA_13 PF13166.1 EAU83275.1 - 0.013 14.0 2.2 0.014 13.9 1.5 1.0 1 0 0 1 1 1 0 AAA domain FHIPEP PF00771.15 EAU83275.1 - 0.058 11.7 0.5 0.065 11.5 0.3 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4544 PF15077.1 EAU83275.1 - 3.6 7.0 7.6 0.79 9.1 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) AAA_13 PF13166.1 EAU83277.1 - 0.16 10.3 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Nucleoplasmin PF03066.10 EAU83277.1 - 4.2 6.8 9.2 0.25 10.8 1.1 2.3 2 0 0 2 2 2 0 Nucleoplasmin Tet_JBP PF12851.2 EAU83282.2 - 8.4e-14 51.2 0.0 1.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Glyco_hydro_4C PF11975.3 EAU83283.2 - 0.13 12.0 0.4 0.2 11.4 0.3 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain DUF737 PF05300.6 EAU83283.2 - 0.61 10.0 5.5 2.7 7.9 3.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF737) PAZ_siRNAbind PF12212.3 EAU83286.2 - 0.056 13.0 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain S10_plectin PF03501.10 EAU83289.2 - 3e-42 142.3 0.1 4.4e-42 141.8 0.1 1.2 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 EAU83289.2 - 0.043 13.5 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB O-FucT PF10250.4 EAU83290.2 - 7.1e-05 22.0 0.0 0.019 14.0 0.0 2.8 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase SnoaL_2 PF12680.2 EAU83293.1 - 0.0017 18.7 2.1 0.0044 17.3 1.2 1.8 1 1 1 2 2 2 1 SnoaL-like domain Nup160 PF11715.3 EAU83293.1 - 0.1 10.7 0.2 0.1 10.6 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Cytochrom_C PF00034.16 EAU83294.1 - 4.5e-09 37.0 0.0 6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EAU83294.1 - 2.9e-08 33.7 1.8 4.1e-07 30.0 1.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EAU83294.1 - 0.00047 19.6 0.3 0.0023 17.4 0.0 2.1 2 1 1 3 3 3 1 Cytochrome c-550 domain Toxin_60 PF15607.1 EAU83294.1 - 0.071 13.1 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 60 Nucleoplasmin PF03066.10 EAU83295.2 - 7.9 5.9 6.6 2.8 7.4 2.6 1.6 2 0 0 2 2 2 0 Nucleoplasmin MFS_1 PF07690.11 EAU83297.2 - 1.7e-36 125.7 33.4 1.7e-36 125.7 23.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_5 PF12695.2 EAU83299.2 - 2.1e-20 72.9 0.0 3.3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU83299.2 - 1.4e-15 57.8 0.1 1.3e-13 51.3 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU83299.2 - 4.8e-07 29.5 0.1 0.0064 16.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU83299.2 - 2.1e-05 23.8 0.0 0.0001 21.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EAU83299.2 - 0.00035 20.0 0.0 0.15 11.4 0.0 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EAU83299.2 - 0.00036 20.0 0.0 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.8 EAU83299.2 - 0.041 13.4 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 EAU83299.2 - 0.053 12.0 0.3 0.55 8.6 0.1 2.4 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EAU83299.2 - 0.055 13.0 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold GST_N_3 PF13417.1 EAU83301.1 - 2.3e-16 59.7 0.0 4.8e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAU83301.1 - 6.2e-16 58.3 0.1 1.7e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU83301.1 - 2.9e-15 56.0 0.0 5.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU83301.1 - 1.4e-11 44.0 0.1 6.6e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EAU83301.1 - 2.9e-11 43.1 0.0 6.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EAU83301.1 - 0.00037 20.9 0.0 0.00057 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Polysacc_deac_1 PF01522.16 EAU83302.2 - 7.5e-26 90.1 0.0 1.2e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase p450 PF00067.17 EAU83306.2 - 1.4e-72 244.7 0.0 2.1e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1730 PF08331.5 EAU83306.2 - 0.05 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) MIS13 PF08202.6 EAU83308.2 - 1.6e-21 76.6 2.3 7.4e-21 74.5 0.1 2.7 3 0 0 3 3 3 1 Mis12-Mtw1 protein family GST_N_3 PF13417.1 EAU83309.1 - 1.2e-18 67.0 0.0 2e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAU83309.1 - 2.1e-17 63.0 0.0 3.7e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU83309.1 - 1.2e-12 47.6 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU83309.1 - 1.7e-12 47.1 0.0 3.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU83309.1 - 3.7e-09 36.3 0.0 6.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU83309.1 - 3.5e-07 30.6 0.0 4.5e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 EAU83310.2 - 1.6e-65 221.4 0.0 1e-43 149.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 F-box-like PF12937.2 EAU83314.1 - 7.1e-12 44.8 3.1 1.8e-11 43.5 2.1 1.7 1 1 0 1 1 1 1 F-box-like DUF4415 PF14384.1 EAU83314.1 - 0.0021 18.1 0.0 0.0055 16.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4415) F-box PF00646.28 EAU83314.1 - 0.071 12.7 3.5 0.24 11.0 0.0 2.4 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 EAU83314.1 - 0.1 12.3 1.4 3 7.6 0.7 2.9 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EAU83314.1 - 0.15 11.7 8.4 0.29 10.7 0.7 3.2 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) ABC2_membrane PF01061.19 EAU83316.2 - 3.9e-34 117.6 21.1 3.9e-34 117.6 14.6 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 EAU83316.2 - 1.7e-28 99.5 0.1 5.3e-28 98.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EAU83316.2 - 3.9e-10 40.1 0.2 1.5e-09 38.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EAU83316.2 - 2.1e-05 23.7 26.9 4.9e-05 22.5 18.7 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_15 PF13175.1 EAU83316.2 - 8.4e-05 21.7 0.0 0.21 10.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EAU83316.2 - 0.00024 20.5 0.0 0.0062 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EAU83316.2 - 0.0004 19.8 0.1 0.00095 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EAU83316.2 - 0.00092 18.4 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 EGF_2 PF07974.8 EAU83316.2 - 0.0017 18.4 10.4 0.0017 18.4 7.2 3.7 3 0 0 3 3 3 1 EGF-like domain AAA_16 PF13191.1 EAU83316.2 - 0.014 15.3 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ATP-synt_ab PF00006.20 EAU83316.2 - 0.025 14.1 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.14 EAU83316.2 - 0.025 13.8 0.0 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EAU83316.2 - 0.026 14.4 0.1 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU83316.2 - 0.042 13.4 0.1 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain GBP PF02263.14 EAU83316.2 - 0.043 12.8 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_22 PF13401.1 EAU83316.2 - 0.055 13.6 0.1 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAU83316.2 - 0.061 14.1 0.0 0.13 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU83316.2 - 0.086 13.1 0.1 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU83316.2 - 0.16 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EAU83316.2 - 0.24 10.0 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein hEGF PF12661.2 EAU83316.2 - 1.4 9.1 29.7 0.5 10.5 1.7 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF Ank_2 PF12796.2 EAU83317.2 - 7.3e-19 67.8 1.1 9.1e-13 48.3 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAU83317.2 - 1.3e-15 56.2 0.2 4.6e-06 26.1 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EAU83317.2 - 3.6e-12 46.4 0.5 1.8e-05 25.1 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU83317.2 - 7.1e-10 38.8 0.5 8.2e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU83317.2 - 4.1e-09 35.7 0.5 0.006 16.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat FpoO PF10621.4 EAU83317.2 - 0.0093 16.0 0.2 0.1 12.6 0.0 2.1 1 1 1 2 2 2 1 F420H2 dehydrogenase subunit FpoO zf-MYND PF01753.13 EAU83318.2 - 6.8e-11 41.8 15.2 1.4e-10 40.8 10.5 1.5 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.2 EAU83318.2 - 7.5e-10 39.0 0.0 0.00011 22.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAU83318.2 - 6.2e-09 35.2 0.0 0.0002 21.0 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 EAU83318.2 - 3.5e-07 30.5 0.0 0.071 13.6 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU83318.2 - 3.8e-06 26.9 0.0 0.055 13.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU83318.2 - 1.2e-05 25.0 0.2 0.016 15.4 0.0 4.4 6 0 0 6 6 6 1 Ankyrin repeat DUF2256 PF10013.4 EAU83318.2 - 0.0097 15.6 4.3 0.02 14.6 3.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-ribbon_3 PF13248.1 EAU83318.2 - 0.036 13.2 2.4 0.086 12.0 1.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain TYW3 PF02676.9 EAU83329.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase TYW3 FlgN PF05130.7 EAU83329.1 - 0.07 13.3 0.7 0.16 12.1 0.5 1.7 1 1 0 1 1 1 0 FlgN protein Tropomyosin_1 PF12718.2 EAU83331.1 - 0.0031 17.3 1.1 0.0072 16.1 0.8 1.5 1 0 0 1 1 1 1 Tropomyosin like MscS_porin PF12795.2 EAU83331.1 - 0.049 12.9 1.6 0.099 11.9 1.1 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain IncA PF04156.9 EAU83331.1 - 0.17 11.5 0.5 0.28 10.7 0.4 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 EAU83331.1 - 0.45 9.1 0.3 0.69 8.5 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-MYND PF01753.13 EAU83334.1 - 3.4e-11 42.8 9.7 9.3e-11 41.4 6.8 1.8 1 0 0 1 1 1 1 MYND finger DUF1627 PF07789.7 EAU83336.1 - 0.0052 16.3 0.0 0.0061 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1627) Syntaxin-6_N PF09177.6 EAU83336.1 - 0.034 14.5 0.4 0.2 12.0 0.2 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4201 PF13870.1 EAU83336.1 - 0.072 12.5 0.2 0.092 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Ribophorin_II PF05817.9 EAU83336.1 - 0.091 10.9 0.0 0.1 10.7 0.0 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II DUF3125 PF11323.3 EAU83336.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3125) PPI_Ypi1 PF07491.6 EAU83337.2 - 4.4e-24 83.8 0.7 4.4e-24 83.8 0.5 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor FAM104 PF15434.1 EAU83337.2 - 0.031 14.4 5.7 0.062 13.4 3.7 1.7 1 1 0 1 1 1 0 Family 104 IDO PF01231.13 EAU83338.1 - 6.4e-109 364.1 0.0 8e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EAU83338.1 - 0.026 13.0 0.0 2.2 6.7 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1864) DUF4140 PF13600.1 EAU83339.2 - 0.043 14.2 2.8 0.71 10.3 0.2 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FH2 PF02181.18 EAU83339.2 - 0.13 11.1 1.5 0.26 10.1 0.5 1.7 1 1 1 2 2 2 0 Formin Homology 2 Domain Prefoldin_2 PF01920.15 EAU83339.2 - 1.6 8.5 7.5 5.5 6.8 5.2 1.9 1 1 0 1 1 1 0 Prefoldin subunit FAST_2 PF08368.7 EAU83344.1 - 0.12 12.7 0.0 0.39 11.1 0.0 1.8 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Cauli_VI PF01693.11 EAU83345.1 - 0.0062 16.5 0.2 0.014 15.4 0.1 1.6 2 0 0 2 2 2 1 Caulimovirus viroplasmin DUF3560 PF12083.3 EAU83346.2 - 0.082 12.9 1.6 0.22 11.5 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) C2 PF00168.25 EAU83349.2 - 2.9e-08 33.4 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain PS_Dcarbxylase PF02666.10 EAU83350.1 - 3.3e-56 189.7 0.0 4.9e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EAU83350.1 - 1.6e-15 56.6 0.0 4.5e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 EAU83350.1 - 0.00033 20.7 0.2 0.00073 19.6 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair zf-MYND PF01753.13 EAU83356.2 - 3.2e-09 36.5 5.4 4.5e-09 36.0 3.7 1.3 1 0 0 1 1 1 1 MYND finger SOBP PF15279.1 EAU83361.2 - 0.037 14.4 4.2 0.053 13.8 2.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2984 PF11203.3 EAU83361.2 - 0.066 13.3 2.2 0.069 13.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) Polysacc_deac_1 PF01522.16 EAU83363.2 - 7.4e-26 90.2 0.0 1.4e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase YtpI PF14007.1 EAU83364.2 - 0.099 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 YtpI-like protein DUF3533 PF12051.3 EAU83366.2 - 1.5e-88 297.1 10.8 1.5e-74 251.0 7.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3533) ABC2_membrane_4 PF12730.2 EAU83366.2 - 0.024 13.7 25.9 0.047 12.8 17.9 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein MotB_plug PF13677.1 EAU83366.2 - 0.23 10.7 1.5 4.6 6.6 0.0 2.7 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB DUF3533 PF12051.3 EAU83367.2 - 6.5e-88 295.0 8.5 8e-88 294.7 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Polysacc_deac_1 PF01522.16 EAU83368.2 - 3.2e-26 91.3 0.0 6.5e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EAU83368.2 - 0.18 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 APH PF01636.18 EAU83369.2 - 5.6e-08 32.8 0.2 1.5e-07 31.3 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family HTH_3 PF01381.17 EAU83369.2 - 3.5e-05 23.5 0.2 7.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix Fructosamin_kin PF03881.9 EAU83369.2 - 0.032 13.1 0.7 0.63 8.9 0.0 2.3 2 0 0 2 2 2 0 Fructosamine kinase HTH_19 PF12844.2 EAU83369.2 - 0.038 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_25 PF13413.1 EAU83369.2 - 0.22 11.1 1.2 0.35 10.5 0.3 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain EcKinase PF02958.15 EAU83369.2 - 0.26 10.4 0.0 0.48 9.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase zf-MYND PF01753.13 EAU83370.2 - 2.3e-09 36.9 11.6 4.5e-09 36.0 8.0 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU83370.2 - 0.078 12.2 1.8 0.14 11.5 1.2 1.4 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 EAU83371.2 - 6.8e-09 35.4 4.5 1.5e-08 34.3 3.1 1.6 1 0 0 1 1 1 1 MYND finger CitG PF01874.11 EAU83371.2 - 0.026 13.7 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Lon_C PF05362.8 EAU83375.2 - 8.8e-64 214.5 0.3 3.1e-63 212.7 0.3 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EAU83375.2 - 4.8e-25 88.4 1.8 9e-25 87.5 0.0 2.3 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EAU83375.2 - 2.8e-17 63.1 0.0 1.8e-16 60.5 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EAU83375.2 - 3.2e-07 29.8 0.5 9.5e-07 28.3 0.0 2.1 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EAU83375.2 - 2.1e-05 24.5 0.2 0.00011 22.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU83375.2 - 4.7e-05 23.5 0.0 0.0003 20.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAU83375.2 - 0.00015 21.4 0.0 0.00066 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EAU83375.2 - 0.0033 17.3 0.0 0.031 14.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EAU83375.2 - 0.005 17.6 0.2 0.019 15.7 0.2 2.1 1 0 0 1 1 1 1 AAA domain ClpB_D2-small PF10431.4 EAU83375.2 - 0.015 15.1 1.0 0.046 13.6 0.0 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.1 EAU83375.2 - 0.023 14.9 1.6 0.088 13.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.9 EAU83376.1 - 0.1 10.6 0.1 0.11 10.4 0.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Tankyrase_bdg_C PF15327.1 EAU83376.1 - 0.26 11.4 2.6 0.24 11.5 0.3 1.9 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain Rsc14 PF08586.5 EAU83376.1 - 0.4 11.1 0.1 0.4 11.1 0.1 1.7 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF2457 PF10446.4 EAU83376.1 - 6 5.4 17.5 10 4.6 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-MYND PF01753.13 EAU83378.2 - 1.9e-09 37.1 4.5 4.1e-09 36.1 3.1 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EAU83379.1 - 7.2e-10 38.5 11.0 1.7e-09 37.4 7.6 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU83379.1 - 5.3 6.9 7.7 2.8 7.8 3.6 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 NUDIX PF00293.23 EAU83380.2 - 5.9e-05 22.7 0.1 7e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain PHO4 PF01384.15 EAU83382.1 - 6.2e-106 353.7 16.6 7.5e-106 353.4 11.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF2474 PF10617.4 EAU83383.2 - 0.0092 15.5 2.0 0.0092 15.5 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2474) VKOR PF07884.9 EAU83383.2 - 9.4 6.0 9.9 2.8 7.7 0.6 2.3 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Ricin_B_lectin PF00652.17 EAU83384.2 - 2.1e-19 69.7 2.3 8.5e-16 58.1 0.7 1.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU83384.2 - 1.9e-10 41.0 0.2 4.9e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like F-box-like PF12937.2 EAU83385.2 - 3.2e-08 33.1 2.9 1.2e-07 31.3 2.0 2.1 1 1 0 1 1 1 1 F-box-like G0-G1_switch_2 PF15103.1 EAU83386.2 - 0.15 12.2 0.6 0.44 10.8 0.4 1.8 1 1 0 1 1 1 0 G0/G1 switch protein 2 E1_dh PF00676.15 EAU83388.1 - 8.2e-112 372.7 0.1 9.7e-112 372.5 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EAU83388.1 - 5.6e-05 22.2 0.0 0.0001 21.3 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EAU83388.1 - 0.0008 19.0 0.8 0.0014 18.1 0.6 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 EAU83388.1 - 0.031 13.0 0.0 0.059 12.1 0.0 1.4 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain F-box-like PF12937.2 EAU83389.2 - 0.00014 21.5 1.0 0.00014 21.5 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU83392.2 - 7.2e-06 25.6 0.2 1.9e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.13 EAU83393.1 - 1.2e-11 44.2 5.9 3.2e-11 42.9 4.1 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU83393.1 - 0.019 14.8 2.7 0.046 13.5 1.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1498 PF07385.7 EAU83393.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) HMG_box PF00505.14 EAU83395.2 - 5.1e-05 23.4 2.5 8.6e-05 22.7 1.3 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.8 EAU83395.2 - 0.0014 18.8 2.4 0.0014 18.8 1.7 1.6 1 1 1 2 2 2 1 YABBY protein HMG_box_2 PF09011.5 EAU83395.2 - 0.0022 18.3 4.5 0.0067 16.7 3.1 1.9 1 1 0 1 1 1 1 HMG-box domain zf-MYND PF01753.13 EAU83396.2 - 2.8e-11 43.0 7.0 6.1e-11 42.0 4.8 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU83396.2 - 0.0022 17.8 2.0 0.0065 16.3 1.4 1.8 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.2 EAU83397.2 - 1.7e-05 24.4 0.2 5.1e-05 22.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like NAD_binding_10 PF13460.1 EAU83398.1 - 4.3e-15 56.1 0.0 5.9e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAU83398.1 - 6.6e-06 25.5 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EAU83398.1 - 0.0071 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EAU83398.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU83399.1 - 3.4e-17 63.0 0.0 5.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAU83399.1 - 2.9e-06 26.7 0.1 6.1e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EAU83399.1 - 0.00044 20.1 0.1 0.00084 19.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU83399.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain Aldo_ket_red PF00248.16 EAU83400.2 - 1.6e-59 201.1 0.0 1.8e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TFIIF_beta PF02270.10 EAU83402.1 - 7.6e-51 173.5 0.0 1.2e-37 130.1 0.0 2.6 2 1 0 2 2 2 2 Transcription initiation factor IIF, beta subunit CAF1A PF12253.3 EAU83402.1 - 2.8 8.1 10.3 4.7 7.3 0.0 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A PhzC-PhzF PF02567.11 EAU83403.1 - 9.3e-24 84.1 0.0 7.5e-16 58.1 0.0 3.0 2 1 0 2 2 2 2 Phenazine biosynthesis-like protein CBF PF03914.12 EAU83418.2 - 1.9e-24 86.0 0.0 1.9e-24 86.0 0.0 3.3 3 0 0 3 3 3 1 CBF/Mak21 family Gpi1 PF05024.10 EAU83419.2 - 9.4e-45 152.6 8.5 9.4e-45 152.6 5.9 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ras PF00071.17 EAU83420.1 - 6.8e-55 184.8 0.0 7.8e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU83420.1 - 2.4e-16 60.2 0.0 3.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU83420.1 - 8e-07 28.4 0.0 1.6e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU83420.1 - 0.00029 20.0 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EAU83420.1 - 0.071 12.5 0.0 5.1 6.5 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EAU83420.1 - 0.094 12.8 0.1 1.2 9.2 0.0 2.4 2 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EAU83420.1 - 0.14 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DAO PF01266.19 EAU83421.1 - 1.4e-39 135.9 0.0 1.8e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAU83421.1 - 0.0031 17.6 0.0 3.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU83421.1 - 0.02 14.8 0.5 0.067 13.2 0.4 2.0 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain OPT PF03169.10 EAU83423.1 - 1.1e-191 638.5 59.9 1.2e-191 638.3 41.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SMC_N PF02463.14 EAU83424.2 - 3.2e-55 186.7 32.0 1.3e-54 184.7 22.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAU83424.2 - 8.5e-21 74.1 0.1 8.5e-21 74.1 0.1 3.0 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EAU83424.2 - 1.3e-11 45.0 13.8 4.4e-06 26.8 0.2 3.7 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EAU83424.2 - 1.7e-06 27.4 0.8 8.6e-05 21.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain IncA PF04156.9 EAU83424.2 - 6.6e-05 22.5 14.5 6.6e-05 22.5 10.1 7.3 3 2 3 6 6 6 3 IncA protein AAA_23 PF13476.1 EAU83424.2 - 0.0033 17.7 129.3 0.0065 16.8 39.2 6.7 2 2 0 2 2 2 1 AAA domain DUF3552 PF12072.3 EAU83424.2 - 0.005 16.0 18.6 0.005 16.0 12.9 7.8 4 2 3 7 7 7 2 Domain of unknown function (DUF3552) Apc5 PF12862.2 EAU83424.2 - 0.06 13.1 2.7 0.52 10.1 0.1 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Reo_sigmaC PF04582.7 EAU83424.2 - 0.085 12.0 25.4 0.0081 15.3 2.4 4.7 3 2 1 4 4 4 0 Reovirus sigma C capsid protein DUF1524 PF07510.6 EAU83427.2 - 2.9e-07 30.4 0.0 1.4e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1524) Cellulase PF00150.13 EAU83428.2 - 5.2e-31 107.8 4.1 8.8e-31 107.1 2.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_C12 PF01088.16 EAU83429.2 - 1.9e-42 144.8 0.0 1e-40 139.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ASXH PF13919.1 EAU83430.1 - 1.1e-26 93.2 0.0 1.7e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Asx homology domain JmjC PF02373.17 EAU83432.2 - 4.1e-39 133.3 0.2 8.1e-39 132.3 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EAU83432.2 - 9e-15 53.9 0.4 2e-14 52.8 0.2 1.6 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 EAU83432.2 - 4.4e-14 52.3 0.6 1.1e-13 51.0 0.4 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EAU83432.2 - 4.1e-12 46.0 0.5 4.1e-12 46.0 0.3 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.24 EAU83432.2 - 0.027 14.1 2.8 0.076 12.7 1.9 1.8 1 0 0 1 1 1 0 PHD-finger CAP59_mtransfer PF11735.3 EAU83437.1 - 1.3e-45 155.5 0.0 2.4e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HAP1_N PF04849.8 EAU83439.2 - 7.2e-05 21.8 0.1 7.2e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region bZIP_1 PF00170.16 EAU83439.2 - 0.0013 18.6 0.9 0.0013 18.6 0.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor ADIP PF11559.3 EAU83439.2 - 0.0015 18.4 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EAU83439.2 - 0.0023 17.3 0.5 0.0037 16.7 0.0 1.6 2 0 0 2 2 2 1 Septum formation initiator Tropomyosin PF00261.15 EAU83439.2 - 0.021 13.8 0.4 0.021 13.8 0.3 1.5 2 0 0 2 2 2 0 Tropomyosin ATG16 PF08614.6 EAU83439.2 - 0.037 13.8 2.6 0.07 12.9 1.8 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MAGSP PF03082.9 EAU83439.2 - 0.052 12.9 0.3 0.073 12.4 0.2 1.1 1 0 0 1 1 1 0 Male accessory gland secretory protein TMF_TATA_bd PF12325.3 EAU83439.2 - 0.055 13.2 0.9 0.097 12.4 0.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MAD PF05557.8 EAU83439.2 - 0.058 11.4 0.4 0.078 11.0 0.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein CAGE1 PF15066.1 EAU83439.2 - 0.064 11.6 0.0 0.064 11.6 0.0 1.1 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family Shugoshin_N PF07558.6 EAU83439.2 - 0.19 11.4 1.5 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF972 PF06156.8 EAU83439.2 - 0.25 11.6 1.0 0.32 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Striatin PF08232.7 EAU83439.2 - 0.29 11.4 3.9 0.13 12.6 0.5 1.8 2 0 0 2 2 2 0 Striatin family TMF_DNA_bd PF12329.3 EAU83439.2 - 2.6 7.9 6.3 0.26 11.1 0.6 2.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding F-box-like PF12937.2 EAU83441.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like NACHT PF05729.7 EAU83442.2 - 5.6e-07 29.3 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EAU83442.2 - 0.012 15.8 0.0 0.042 14.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU83442.2 - 0.047 13.6 0.1 0.31 11.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Cys_Met_Meta_PP PF01053.15 EAU83443.2 - 5e-134 446.4 0.0 6.1e-134 446.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EAU83443.2 - 4.4e-14 52.2 0.3 2.8e-13 49.6 0.2 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EAU83443.2 - 1.4e-09 37.3 0.1 2.2e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EAU83443.2 - 3.2e-08 32.7 1.5 3.3e-08 32.6 0.3 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAU83443.2 - 3.4e-07 29.6 0.0 6.2e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EAU83443.2 - 0.0033 16.1 0.1 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EAU83443.2 - 0.0055 15.0 0.1 0.0078 14.5 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase F-box-like PF12937.2 EAU83444.1 - 2.3e-07 30.4 1.7 6.2e-07 29.0 1.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAU83444.1 - 0.0055 16.4 0.6 5.1 6.9 0.1 3.5 3 0 0 3 3 3 2 Leucine rich repeat Glyco_hydro_cc PF11790.3 EAU83450.1 - 5.8e-69 232.1 5.1 6.7e-69 231.9 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_39 PF01229.12 EAU83450.1 - 0.07 11.5 0.0 0.099 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 39 Apc1 PF12859.2 EAU83451.1 - 0.075 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF2318 PF10080.4 EAU83451.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) MMR_HSR1 PF01926.18 EAU83452.2 - 2.1e-15 56.6 0.3 2.4e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EAU83452.2 - 0.00066 20.1 0.0 0.51 10.8 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein Dynamin_N PF00350.18 EAU83452.2 - 0.00097 18.9 1.2 1.3 8.8 0.1 3.2 4 0 0 4 4 4 2 Dynamin family FeoB_N PF02421.13 EAU83452.2 - 0.002 17.4 0.1 0.0058 15.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.1 EAU83452.2 - 0.005 16.9 0.1 5.4 7.1 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAU83452.2 - 0.013 14.7 0.2 0.064 12.4 0.2 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EAU83452.2 - 0.016 14.6 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EAU83452.2 - 0.034 12.9 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EAU83452.2 - 0.063 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EAU83452.2 - 0.065 12.6 0.0 6.6 6.1 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EAU83452.2 - 0.12 13.2 0.1 3.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAU83452.2 - 0.16 11.9 0.7 1 9.3 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 EAU83453.2 - 3e-42 144.5 0.0 3.7e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU83453.2 - 1e-35 123.1 0.0 1.2e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU83453.2 - 0.002 17.9 0.0 0.0057 16.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EAU83453.2 - 0.0036 16.3 0.0 0.0083 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU83453.2 - 0.019 13.9 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 EAU83453.2 - 0.11 11.3 0.0 0.29 9.9 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.17 EAU83453.2 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Gti1_Pac2 PF09729.4 EAU83455.1 - 1.2e-56 191.1 0.0 1.2e-56 191.1 0.0 1.9 2 1 0 2 2 2 1 Gti1/Pac2 family WSC PF01822.14 EAU83456.1 - 2.2e-67 223.0 52.0 1.3e-18 66.6 5.2 4.3 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 EAU83456.1 - 4e-28 98.1 0.0 9.5e-27 93.6 0.0 2.6 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EAU83456.1 - 1.7e-21 76.1 0.0 4.3e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EAU83456.1 - 0.00073 19.2 0.2 0.18 11.5 0.0 3.4 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EAU83456.1 - 0.011 15.8 0.2 3.7 7.8 0.0 4.1 4 1 1 5 5 5 0 Kelch motif Glyco_trans_2_3 PF13632.1 EAU83457.1 - 3.4e-54 183.5 0.5 3.4e-54 183.5 0.3 3.4 4 1 1 5 5 5 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAU83457.1 - 3.7e-09 36.7 0.0 7.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAU83457.1 - 0.00075 19.2 0.0 0.0051 16.5 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.16 EAU83458.2 - 1.1e-23 83.4 0.1 2.1e-23 82.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Metaviral_G PF09595.5 EAU83458.2 - 2.2 7.8 12.3 3.7 7.1 8.5 1.3 1 0 0 1 1 1 0 Metaviral_G glycoprotein Ras PF00071.17 EAU83465.2 - 5.8e-54 181.8 0.1 6.8e-54 181.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU83465.2 - 5e-18 65.7 0.1 9.6e-18 64.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAU83465.2 - 2.2e-13 49.8 0.0 3.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU83465.2 - 6.1e-07 28.8 0.0 7e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU83465.2 - 3.7e-06 26.8 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU83465.2 - 0.00099 18.5 0.1 0.0064 15.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EAU83465.2 - 0.016 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EAU83465.2 - 0.019 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 EAU83465.2 - 0.097 11.8 0.1 0.23 10.6 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EAU83465.2 - 0.12 12.2 0.0 0.27 11.0 0.0 1.9 1 1 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 EAU83465.2 - 0.13 12.1 0.2 0.38 10.6 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EAU83465.2 - 0.24 10.0 1.6 2.7 6.5 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit DUF605 PF04652.11 EAU83466.2 - 1.5 8.1 11.1 2.3 7.5 7.7 1.2 1 0 0 1 1 1 0 Vta1 like DUF4243 PF14027.1 EAU83469.2 - 2.5e-84 283.5 0.3 3.7e-78 263.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4243) AT_hook PF02178.14 EAU83472.2 - 0.029 14.0 3.0 0.029 14.0 2.1 3.3 3 0 0 3 3 3 0 AT hook motif DUF4611 PF15387.1 EAU83472.2 - 0.5 10.5 5.0 0.5 10.5 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 EAU83472.2 - 0.8 9.9 6.1 3.1 8.0 0.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BRF1 PF07741.8 EAU83472.2 - 2 8.6 5.2 7.8 6.8 0.5 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DDE_5 PF13546.1 EAU83472.2 - 3.2 6.5 10.9 3.6 6.3 0.9 2.2 1 1 1 2 2 2 0 DDE superfamily endonuclease AhpC-TSA PF00578.16 EAU83474.2 - 2.9e-31 107.7 0.0 7.8e-31 106.3 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EAU83474.2 - 9.4e-13 47.5 0.0 1.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EAU83474.2 - 4.6e-11 42.4 0.0 1.3e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Redoxin cEGF PF12662.2 EAU83478.1 - 0.0098 15.5 0.8 0.0098 15.5 0.5 4.9 4 1 0 4 4 4 3 Complement Clr-like EGF-like hEGF PF12661.2 EAU83478.1 - 8.3 6.7 9.9 78 3.6 0.3 5.2 4 0 0 4 4 4 0 Human growth factor-like EGF F-box-like PF12937.2 EAU83479.2 - 4.8e-05 22.9 0.2 0.00012 21.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU83479.2 - 0.38 10.4 6.0 13 5.5 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Xan_ur_permease PF00860.15 EAU83480.2 - 8.5e-29 100.2 29.2 4.7e-27 94.4 20.2 2.7 1 1 0 1 1 1 1 Permease family F-box-like PF12937.2 EAU83481.2 - 0.0001 21.9 0.1 0.00024 20.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like FA_hydroxylase PF04116.8 EAU83482.1 - 2.5e-12 47.2 21.6 2.5e-12 47.2 15.0 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Toxin_39 PF15500.1 EAU83482.1 - 0.04 14.0 1.3 0.065 13.3 0.9 1.2 1 0 0 1 1 1 0 Putative RNase-like toxin DUF89 PF01937.14 EAU83482.1 - 0.064 12.0 0.3 0.36 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF89 TFIIB PF00382.14 EAU83484.1 - 6.4e-34 115.5 0.0 4.8e-21 74.3 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EAU83484.1 - 6.1e-15 54.2 1.1 1e-14 53.5 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.1 EAU83484.1 - 0.0011 18.0 0.3 0.34 10.1 0.0 3.5 4 0 0 4 4 4 1 Helix-turn-helix domain of transposase family ISL3 Cyclin_N PF00134.18 EAU83484.1 - 0.024 14.1 0.1 0.053 13.0 0.1 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF2296 PF10058.4 EAU83484.1 - 0.045 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) HTH_23 PF13384.1 EAU83484.1 - 0.052 13.2 0.1 0.92 9.2 0.0 2.9 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 EAU83484.1 - 0.094 12.7 0.1 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain UNC45-central PF11701.3 EAU83484.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Pkinase PF00069.20 EAU83485.2 - 1e-35 123.1 0.0 1.6e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU83485.2 - 1.5e-33 115.9 0.0 2.1e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4238 PF14022.1 EAU83485.2 - 0.00058 19.2 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) APH PF01636.18 EAU83485.2 - 0.032 13.9 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EAU83485.2 - 0.21 10.5 0.0 0.38 9.7 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase F-box-like PF12937.2 EAU83486.1 - 9.6e-07 28.4 0.9 9.6e-07 28.4 0.6 2.2 3 0 0 3 3 3 1 F-box-like Tubulin PF00091.20 EAU83487.1 - 1.8e-70 237.1 0.0 3.4e-70 236.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAU83487.1 - 3.2e-49 166.1 0.1 5.1e-49 165.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EAU83487.1 - 3.2e-06 27.1 0.0 8.6e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EAU83487.1 - 0.0028 17.1 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain CBFD_NFYB_HMF PF00808.18 EAU83488.1 - 1e-16 60.7 1.1 2.3e-16 59.5 0.7 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAU83488.1 - 2.9e-07 30.4 0.2 5.3e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 EAU83488.1 - 0.022 14.5 1.3 0.035 13.8 0.9 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Cwf_Cwc_15 PF04889.7 EAU83488.1 - 9.4 5.8 14.9 13 5.3 10.3 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sld5 PF05916.6 EAU83489.1 - 2.8e-05 24.3 1.0 0.00032 20.9 0.5 2.2 2 0 0 2 2 2 1 GINS complex protein Thioesterase PF00975.15 EAU83489.1 - 0.018 15.2 0.3 0.028 14.6 0.2 1.4 1 1 0 1 1 1 0 Thioesterase domain NACHT PF05729.7 EAU83491.2 - 9.4e-12 44.9 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU83491.2 - 0.00011 22.2 0.2 0.00062 19.8 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EAU83491.2 - 0.00045 20.4 0.0 0.0015 18.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAU83491.2 - 0.043 12.8 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 EAU83491.2 - 0.075 11.8 0.1 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 EAU83491.2 - 0.084 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EAU83491.2 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Peptidase_M48 PF01435.13 EAU83492.1 - 6.6e-45 153.4 0.0 1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF955 PF06114.8 EAU83492.1 - 0.21 11.3 0.7 3.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF955) p450 PF00067.17 EAU83493.2 - 3e-66 223.8 0.0 6.3e-66 222.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ATG22 PF11700.3 EAU83494.2 - 1.2e-119 399.9 6.6 6.2e-68 229.4 0.1 2.8 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like F-box-like PF12937.2 EAU83495.2 - 2.3e-06 27.2 0.5 2.3e-06 27.2 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU83496.1 - 1.2e-06 28.1 1.7 2.5e-06 27.0 1.2 1.6 1 0 0 1 1 1 1 F-box-like DUF3450 PF11932.3 EAU83496.1 - 0.052 12.7 0.7 0.091 12.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.3 EAU83496.1 - 0.094 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding F-box-like PF12937.2 EAU83497.1 - 1.2e-06 28.1 0.8 8.7e-06 25.3 0.2 2.7 2 0 0 2 2 2 1 F-box-like Hydrophobin PF01185.13 EAU83498.1 - 1.1e-10 41.7 9.1 1.4e-10 41.5 6.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF3433 PF11915.3 EAU83499.2 - 9.8e-19 67.3 0.8 9.8e-19 67.3 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) EamA PF00892.15 EAU83500.1 - 1.7e-25 89.4 24.0 3.2e-13 49.8 2.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EAU83500.1 - 3.2e-05 24.0 23.9 0.00012 22.2 1.7 3.4 1 1 2 4 4 4 2 Multidrug resistance efflux transporter zf-C2H2_4 PF13894.1 EAU83502.2 - 0.037 14.3 0.4 0.037 14.3 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU83502.2 - 2.5 8.3 9.9 18 5.6 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding EamA PF00892.15 EAU83503.2 - 7.4e-28 97.1 33.4 2.3e-16 59.9 6.6 2.7 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAU83503.2 - 5.2e-08 33.0 37.3 2.7e-06 27.5 3.9 4.0 2 2 2 4 4 4 2 Multidrug resistance efflux transporter Gemini_AC4_5_2 PF08464.5 EAU83503.2 - 0.07 12.8 0.4 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region OCD_Mu_crystall PF02423.10 EAU83505.1 - 1.3e-19 70.1 3.6 1.3e-12 47.1 0.3 3.2 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family THF_DHG_CYH_C PF02882.14 EAU83505.1 - 0.0028 16.7 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EAU83505.1 - 0.037 14.1 0.0 0.79 9.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EAU83506.2 - 1.4e-29 103.0 0.0 2.8e-16 59.2 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EAU83506.2 - 3.9e-11 42.5 0.0 7.8e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAU83506.2 - 2.1e-07 30.1 0.1 0.00023 20.2 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EAU83506.2 - 2.5e-06 26.8 0.1 1.1e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAU83506.2 - 5.4e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU83506.2 - 0.00032 21.0 0.1 0.0056 17.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU83506.2 - 0.00032 19.2 0.0 0.00058 18.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EAU83506.2 - 0.00082 19.3 0.1 0.00082 19.3 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EAU83506.2 - 0.0031 16.6 0.0 0.0081 15.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EAU83506.2 - 0.007 15.2 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EAU83506.2 - 0.011 15.3 0.6 0.11 12.1 0.0 2.4 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EAU83506.2 - 0.013 14.3 0.1 0.031 13.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EAU83506.2 - 0.017 15.3 0.2 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EAU83506.2 - 0.14 12.2 0.2 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EAU83507.1 - 2.6e-31 108.7 0.0 2.3e-16 59.4 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EAU83507.1 - 8e-17 61.3 0.0 8.4e-13 48.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EAU83507.1 - 3.8e-08 32.8 0.0 1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAU83507.1 - 3.6e-07 30.2 0.0 1e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU83507.1 - 2.3e-06 26.7 0.1 0.00054 18.9 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EAU83507.1 - 2.9e-05 22.7 0.0 0.00011 20.8 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EAU83507.1 - 0.00011 22.1 1.0 0.00023 21.1 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EAU83507.1 - 0.00012 21.0 0.1 0.0014 17.6 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EAU83507.1 - 0.00016 20.6 0.0 0.00054 18.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EAU83507.1 - 0.003 17.6 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU83507.1 - 0.005 17.2 0.1 0.03 14.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU83507.1 - 0.0059 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DUF4027 PF13219.1 EAU83507.1 - 0.032 13.6 0.1 0.067 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Lycopene_cycl PF05834.7 EAU83507.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EAU83507.1 - 0.14 11.8 0.2 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CPSase_L_D2 PF02786.12 EAU83508.2 - 5e-104 346.1 0.3 1.9e-70 236.4 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EAU83508.2 - 2.6e-45 153.1 0.0 6.7e-45 151.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EAU83508.2 - 3e-45 154.0 0.0 3.4e-44 150.5 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EAU83508.2 - 1.8e-44 150.8 0.0 3.7e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EAU83508.2 - 2.5e-41 140.1 0.0 1.2e-19 70.4 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EAU83508.2 - 1.9e-40 137.4 0.1 5.3e-40 136.0 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 EAU83508.2 - 7.7e-37 126.6 0.0 2.2e-36 125.0 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EAU83508.2 - 1.7e-34 119.1 0.1 4.5e-23 81.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EAU83508.2 - 3.4e-20 71.7 0.0 2.2e-19 69.1 0.0 2.6 2 0 0 2 2 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EAU83508.2 - 4e-18 65.2 0.2 7.9e-09 34.6 0.1 3.3 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EAU83508.2 - 4.3e-17 61.9 0.1 1.5e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAU83508.2 - 3.6e-16 59.1 0.4 7.3e-09 35.3 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EAU83508.2 - 4.1e-07 29.6 0.1 0.00035 20.1 0.1 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 EAU83508.2 - 2.1e-06 27.3 0.1 8.8e-05 22.0 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EAU83508.2 - 0.0039 17.0 0.2 0.014 15.2 0.0 2.1 3 0 0 3 3 3 1 ATP-grasp domain GARS_A PF01071.14 EAU83508.2 - 0.0081 15.7 0.1 0.76 9.3 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EAU83508.2 - 0.013 14.7 0.0 0.91 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Cyt-b5 PF00173.23 EAU83509.1 - 4.4e-10 39.2 0.0 5.7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2236 PF09995.4 EAU83510.2 - 5.5e-13 48.7 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) TAFII28 PF04719.9 EAU83511.2 - 5.1e-29 99.9 0.0 6.9e-29 99.4 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 EAU83511.2 - 0.0054 16.7 0.0 0.0083 16.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hydantoinase_A PF01968.13 EAU83511.2 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase AAA_16 PF13191.1 EAU83514.2 - 0.00019 21.5 0.0 0.00053 20.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU83514.2 - 0.0025 17.9 0.0 0.007 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAU83514.2 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EAU83514.2 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF155 PF02582.9 EAU83515.1 - 0.0093 15.8 0.2 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SpoVAE PF14097.1 EAU83515.1 - 0.032 13.6 0.8 0.049 13.0 0.6 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Ribosomal_L27 PF01016.14 EAU83515.1 - 0.065 13.0 0.1 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L27 protein DUF2572 PF10833.3 EAU83515.1 - 0.068 12.5 0.4 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) Sugar_tr PF00083.19 EAU83517.1 - 1.1e-122 409.8 12.4 1.3e-122 409.6 8.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU83517.1 - 3.3e-17 62.2 32.3 1.9e-12 46.5 8.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HlyIII PF03006.15 EAU83517.1 - 9.3 5.5 12.5 3.6 6.9 0.1 3.1 3 1 0 3 3 3 0 Haemolysin-III related DUF3446 PF11928.3 EAU83518.2 - 0.1 12.7 11.6 17 5.6 7.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) PAT1 PF09770.4 EAU83518.2 - 5.4 5.1 10.9 7.4 4.6 7.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box PF00646.28 EAU83519.2 - 0.0019 17.8 0.0 0.0056 16.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU83519.2 - 0.0095 15.6 0.0 0.031 14.0 0.0 1.9 2 0 0 2 2 2 1 F-box-like FPL PF09758.4 EAU83519.2 - 0.15 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein F-box-like PF12937.2 EAU83522.1 - 5.7e-06 25.9 1.0 1.7e-05 24.4 0.3 2.2 2 0 0 2 2 2 1 F-box-like Gryzun PF07919.7 EAU83522.1 - 0.0092 14.3 0.0 0.016 13.5 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi DUF992 PF06186.6 EAU83522.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF992) NACHT PF05729.7 EAU83523.2 - 8.1e-10 38.5 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU83523.2 - 0.0001 22.3 0.2 0.00029 20.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU83523.2 - 0.0026 17.9 0.0 0.0077 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EAU83523.2 - 0.29 10.0 0.0 0.42 9.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain zf-MYND PF01753.13 EAU83524.2 - 2.1e-11 43.5 6.4 3.6e-11 42.7 4.4 1.4 1 0 0 1 1 1 1 MYND finger SET PF00856.23 EAU83524.2 - 2e-06 28.2 0.0 7.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 SET domain DnaJ_CXXCXGXG PF00684.14 EAU83524.2 - 0.031 14.3 0.1 0.061 13.3 0.1 1.4 1 0 0 1 1 1 0 DnaJ central domain Prenyltrans PF00432.16 EAU83525.1 - 1.3e-60 200.5 5.7 4.1e-12 45.4 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAU83525.1 - 3.1e-47 159.6 0.0 4.1e-14 52.9 0.0 3.8 1 1 4 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAU83525.1 - 2.6e-09 37.0 0.0 4.5e-06 26.6 0.0 3.2 1 1 1 3 3 3 2 Prenyltransferase-like zf-CSL PF05207.8 EAU83526.1 - 6.3e-24 83.2 0.9 6.3e-24 83.2 0.6 1.7 2 0 0 2 2 2 1 CSL zinc finger zinc_ribbon_5 PF13719.1 EAU83526.1 - 0.051 13.1 1.1 0.08 12.5 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.7 EAU83526.1 - 0.057 11.7 0.6 0.077 11.3 0.4 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF688 PF05097.7 EAU83526.1 - 0.064 12.1 1.1 0.071 12.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Zn-ribbon_8 PF09723.5 EAU83526.1 - 0.07 13.0 1.5 0.14 12.1 1.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Nucleoplasmin PF03066.10 EAU83526.1 - 0.11 12.0 9.2 0.14 11.7 6.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Paf1 PF03985.8 EAU83526.1 - 0.14 10.9 6.4 0.18 10.5 4.5 1.1 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.1 EAU83526.1 - 0.14 11.8 1.7 0.19 11.3 1.2 1.2 1 0 0 1 1 1 0 FAM176 family zinc_ribbon_4 PF13717.1 EAU83526.1 - 0.17 11.6 1.3 0.27 10.9 0.9 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Sigma70_ner PF04546.8 EAU83526.1 - 0.21 11.1 7.6 0.24 10.9 5.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EAU83526.1 - 0.23 9.3 9.4 0.24 9.3 6.5 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.6 EAU83526.1 - 0.26 11.0 4.3 0.34 10.7 3.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 EAU83526.1 - 0.35 9.0 5.0 0.33 9.1 3.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 EAU83526.1 - 0.84 8.2 11.4 0.86 8.2 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EAU83526.1 - 1 8.5 7.3 1.1 8.5 5.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EAU83526.1 - 1.9 6.4 5.4 1.8 6.4 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein EBV-NA3 PF05009.7 EAU83526.1 - 7.6 5.7 6.8 8.9 5.4 4.7 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) F-box-like PF12937.2 EAU83528.1 - 0.00063 19.4 1.3 0.0015 18.1 0.9 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU83528.1 - 0.048 13.2 7.1 0.37 10.4 0.0 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Mito_carr PF00153.22 EAU83529.1 - 1.3e-19 69.6 6.8 2.6e-07 30.2 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box PF00646.28 EAU83530.2 - 0.0009 18.8 0.1 0.0045 16.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAU83530.2 - 0.0017 18.0 0.7 0.032 13.9 0.2 2.6 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 EAU83530.2 - 0.059 13.5 0.6 15 6.3 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EAU83530.2 - 0.18 11.9 1.3 19 5.6 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat F-box PF00646.28 EAU83531.2 - 0.00025 20.6 1.0 0.0056 16.2 0.0 3.2 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EAU83531.2 - 0.00039 20.0 0.0 0.0053 16.4 0.0 2.6 2 0 0 2 2 2 1 F-box-like Piwi PF02171.12 EAU83532.1 - 2.1e-77 260.0 0.0 2.9e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EAU83532.1 - 1.4e-12 47.0 0.0 3.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EAU83532.1 - 5.2e-09 35.3 0.1 1.4e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) NACHT PF05729.7 EAU83537.2 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EAU83537.2 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_M1 PF01433.15 EAU83538.2 - 3.8e-57 194.1 0.0 7e-57 193.2 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EAU83538.2 - 1.1e-27 96.3 0.0 3e-27 94.9 0.0 1.7 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EAU83538.2 - 1.1e-13 51.3 0.3 1.8e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EAU83538.2 - 0.42 10.6 3.3 5.1 7.0 2.3 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase TPR_11 PF13414.1 EAU83539.1 - 3.5e-52 173.9 16.6 6.1e-13 48.2 0.0 7.5 4 2 5 9 9 9 8 TPR repeat TPR_1 PF00515.23 EAU83539.1 - 4.3e-41 136.8 12.6 5.5e-06 25.7 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 EAU83539.1 - 1.6e-39 130.6 12.0 1.8e-05 24.2 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_16 PF13432.1 EAU83539.1 - 5.3e-27 93.8 9.3 1.1e-06 29.1 0.2 7.4 6 1 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EAU83539.1 - 2.4e-24 83.4 4.2 5e-05 23.1 0.0 9.0 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EAU83539.1 - 1.4e-18 65.2 12.5 0.02 14.6 0.0 9.8 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAU83539.1 - 7.2e-18 64.3 12.6 0.00047 20.0 0.3 7.6 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EAU83539.1 - 1.1e-16 59.2 4.2 0.29 11.0 0.0 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAU83539.1 - 2.2e-16 58.8 16.0 0.00011 22.5 0.0 9.1 6 4 2 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EAU83539.1 - 9.4e-16 57.9 13.6 0.00053 20.2 0.0 7.1 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAU83539.1 - 5.2e-13 48.6 2.4 0.00082 19.1 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAU83539.1 - 6.5e-09 35.6 12.5 0.72 10.4 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat MIT PF04212.13 EAU83539.1 - 5.2e-05 23.0 8.6 2.8 7.8 0.1 6.1 6 1 0 6 6 4 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EAU83539.1 - 6e-05 23.0 13.9 8.3 6.6 0.0 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 EAU83539.1 - 0.00012 21.9 6.7 0.13 12.1 0.0 5.1 4 2 2 6 6 6 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.3 EAU83539.1 - 0.0007 18.4 0.0 0.0007 18.4 0.0 3.6 2 2 1 4 4 3 1 NMDA receptor-regulated protein 1 SHNi-TPR PF10516.4 EAU83539.1 - 0.0069 15.6 5.3 10 5.4 0.1 4.9 5 0 0 5 5 5 0 SHNi-TPR SpoIIIAH PF12685.2 EAU83539.1 - 0.008 15.6 0.7 0.008 15.6 0.5 2.5 3 0 0 3 3 3 1 SpoIIIAH-like protein MAS20 PF02064.10 EAU83539.1 - 0.012 15.5 2.3 3.7 7.4 0.0 4.6 5 1 1 6 6 6 0 MAS20 protein import receptor TPR_10 PF13374.1 EAU83539.1 - 0.034 14.0 1.5 21 5.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EAU83539.1 - 0.038 14.6 0.3 28 5.5 0.3 4.0 3 0 0 3 3 2 0 Sel1 repeat PPR PF01535.15 EAU83539.1 - 0.18 11.8 0.2 31 4.8 0.0 3.5 3 0 0 3 3 2 0 PPR repeat EOS1 PF12326.3 EAU83540.2 - 1.6e-16 60.3 0.5 2.7e-16 59.5 0.3 1.4 1 0 0 1 1 1 1 N-glycosylation protein p450 PF00067.17 EAU83541.2 - 1.9e-33 115.6 0.0 2.4e-16 59.3 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 L_biotic_typeA PF04604.8 EAU83541.2 - 0.11 12.1 0.1 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Type-A lantibiotic CBM_1 PF00734.13 EAU83544.2 - 4.9e-15 54.8 10.8 1.2e-14 53.5 7.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain PhoPQ_related PF10142.4 EAU83544.2 - 0.011 14.2 0.2 0.017 13.6 0.1 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Toxin_7 PF05980.7 EAU83544.2 - 0.6 10.1 11.8 0.31 11.1 6.2 2.0 2 0 0 2 2 2 0 Toxin 7 F-box-like PF12937.2 EAU83545.2 - 8.2e-07 28.6 0.3 1.9e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like NUDE_C PF04880.8 EAU83545.2 - 0.078 13.3 0.9 0.22 11.8 0.6 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Pkinase PF00069.20 EAU83547.2 - 6.3e-27 94.3 0.0 1.1e-26 93.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU83547.2 - 3.7e-07 29.4 0.0 3.3e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase UvrB PF12344.3 EAU83547.2 - 0.0074 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Ultra-violet resistance protein B Nup88 PF10168.4 EAU83547.2 - 0.13 10.0 0.0 0.19 9.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore component Glycos_transf_1 PF00534.15 EAU83548.2 - 7.1e-25 87.3 0.0 3.4e-23 81.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAU83548.2 - 9.3e-14 51.8 0.1 1.4e-11 44.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 EAU83548.2 - 1.3e-11 44.5 0.0 3.7e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EAU83548.2 - 3.1e-07 30.5 0.0 9.9e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EAU83548.2 - 0.00046 20.4 0.0 0.00095 19.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Metal_resist PF13801.1 EAU83548.2 - 0.0088 16.0 0.8 0.017 15.1 0.5 1.4 1 0 0 1 1 1 1 Heavy-metal resistance 2OG-FeII_Oxy_2 PF13532.1 EAU83551.1 - 9.4e-24 84.3 0.0 1.3e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAZAP2 PF11029.3 EAU83551.1 - 0.064 13.7 2.0 0.077 13.4 0.2 1.9 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) Rad60-SLD PF11976.3 EAU83554.1 - 1.5e-24 85.4 0.1 2e-24 85.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EAU83554.1 - 1.7e-10 40.0 0.1 2.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family NACHT PF05729.7 EAU83555.2 - 6.9e-08 32.3 0.0 2.1e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAU83555.2 - 0.0028 17.6 0.2 0.021 14.7 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU83555.2 - 0.01 15.9 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EAU83555.2 - 0.093 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EAU83555.2 - 0.21 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.9 EAU83557.2 - 8.9e-27 93.9 0.0 2e-25 89.5 0.0 2.2 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAU83557.2 - 6e-10 39.1 0.0 1.4e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU83557.2 - 1.8e-08 34.2 0.1 2.1e-07 30.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU83557.2 - 0.0015 18.7 0.5 0.0063 16.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 EAU83557.2 - 0.0032 17.5 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EAU83557.2 - 0.0056 16.2 0.3 1.1 8.7 0.2 3.4 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EAU83557.2 - 0.012 15.7 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU83557.2 - 0.021 14.7 0.0 0.091 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 EAU83557.2 - 0.07 11.9 0.0 0.17 10.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EAU83557.2 - 0.076 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EAU83557.2 - 0.092 12.6 0.1 17 5.3 0.0 3.5 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EAU83557.2 - 0.18 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Herpes_Helicase PF02689.9 EAU83557.2 - 0.2 9.3 0.0 0.68 7.5 0.0 1.7 2 0 0 2 2 2 0 Helicase F-box-like PF12937.2 EAU83558.2 - 1.9e-10 40.2 1.8 4.7e-09 35.8 0.2 2.6 2 0 0 2 2 2 2 F-box-like Zn_clus PF00172.13 EAU83562.2 - 0.5 10.3 2.4 1 9.3 1.7 1.5 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PIF1 PF05970.9 EAU83563.2 - 5.6e-24 84.7 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAU83563.2 - 5.6e-13 49.0 0.1 1.4e-12 47.7 0.1 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU83563.2 - 1.2e-07 31.4 0.0 3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU83563.2 - 0.0018 18.0 0.0 0.0049 16.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EAU83563.2 - 0.11 12.6 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SAP PF02037.22 EAU83563.2 - 0.16 11.5 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 SAP domain RicinB_lectin_2 PF14200.1 EAU83564.2 - 5.2e-24 84.6 1.0 8.1e-20 71.1 0.6 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU83564.2 - 6.3e-05 23.0 0.2 0.7 9.9 0.0 3.1 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain Sec7_N PF12783.2 EAU83566.2 - 2.5e-36 124.6 2.8 1.8e-35 121.8 0.2 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EAU83566.2 - 0.00037 19.9 0.0 0.0034 16.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Glyco_transf_15 PF01793.11 EAU83567.1 - 2.4e-135 450.7 7.7 2.9e-135 450.4 5.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GASA PF02704.9 EAU83568.1 - 0.0015 18.4 1.3 0.0028 17.5 0.9 1.4 1 0 0 1 1 1 1 Gibberellin regulated protein PsbM PF05151.7 EAU83570.1 - 0.17 11.4 0.9 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre M protein (PsbM) adh_short PF00106.20 EAU83574.2 - 1.7e-13 50.8 0.8 2.2e-13 50.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase YjeF_N PF03853.10 EAU83574.2 - 1.4e-05 24.7 0.7 7.9e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 YjeF-related protein N-terminus adh_short_C2 PF13561.1 EAU83574.2 - 0.00078 19.2 0.0 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EAU83574.2 - 0.014 15.0 0.2 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_3 PF13920.1 EAU83575.2 - 0.019 14.6 0.6 0.035 13.7 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU83575.2 - 0.43 10.4 3.7 1 9.2 2.6 1.7 1 1 0 1 1 1 0 Ring finger domain Homeobox PF00046.24 EAU83576.2 - 1e-14 53.8 1.0 2.2e-14 52.7 0.7 1.6 1 0 0 1 1 1 1 Homeobox domain Bromodomain PF00439.20 EAU83578.1 - 5.9e-20 70.9 0.0 1.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain G5 PF07501.7 EAU83579.2 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 G5 domain PLDc PF00614.17 EAU83580.1 - 2.5e-12 46.1 3.0 1.4e-07 31.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EAU83580.1 - 1.3e-10 41.1 0.2 2e-07 30.7 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain Terpene_synth_C PF03936.11 EAU83581.1 - 6.8e-07 28.7 0.0 8.7e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Nup84_Nup100 PF04121.8 EAU83582.2 - 1.5e-84 283.9 0.0 2.8e-84 283.1 0.0 1.4 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1250 PF06855.7 EAU83582.2 - 0.065 12.7 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Nic96 PF04097.9 EAU83582.2 - 0.34 8.9 0.6 2.9 5.8 0.4 2.0 1 1 0 1 1 1 0 Nup93/Nic96 Defensin_3 PF08131.6 EAU83583.2 - 0.029 14.3 2.4 0.14 12.1 1.7 2.2 2 1 0 2 2 2 0 Defensin-like peptide family Cellulase PF00150.13 EAU83584.1 - 8.7e-12 44.8 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1212 PF06738.7 EAU83585.2 - 6e-37 126.9 9.7 2.1e-36 125.2 1.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EAU83585.2 - 3.4e-16 59.3 7.3 3.4e-16 59.3 5.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Glyco_transf_15 PF01793.11 EAU83586.1 - 1.5e-136 454.7 11.7 1.8e-136 454.4 8.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PIP5K PF01504.13 EAU83589.2 - 4.3e-55 186.5 0.1 7.4e-55 185.7 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pro_isomerase PF00160.16 EAU83590.2 - 1.8e-28 99.6 0.2 3.3e-28 98.8 0.2 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GMC_oxred_N PF00732.14 EAU83591.2 - 1e-59 202.1 0.0 1.5e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU83591.2 - 1.8e-34 119.1 0.0 4e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EAU83591.2 - 9.8e-06 24.7 0.1 1.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU83591.2 - 0.00049 19.0 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EAU83591.2 - 0.0076 15.3 0.0 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EAU83591.2 - 0.012 14.4 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EAU83591.2 - 0.015 15.1 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU83591.2 - 0.015 14.2 0.5 0.13 11.0 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Gemini_AL1_M PF08283.6 EAU83591.2 - 0.048 13.4 0.3 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Geminivirus rep protein central domain HI0933_like PF03486.9 EAU83591.2 - 0.092 11.1 0.6 0.15 10.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 EAU83591.2 - 0.15 12.1 0.2 0.85 9.6 0.1 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FGGY_C PF02782.11 EAU83592.1 - 0.011 15.4 0.0 0.54 9.8 0.0 2.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EAU83592.1 - 0.042 13.1 0.0 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain DIM1 PF02966.11 EAU83593.2 - 7.3e-69 229.4 0.1 8.2e-69 229.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EAU83593.2 - 0.00011 21.8 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EAU83593.2 - 0.019 15.0 0.2 0.029 14.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 EAU83593.2 - 0.1 12.6 0.0 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like SNF2_N PF00176.18 EAU83594.1 - 1.5e-72 243.9 0.1 1.1e-71 241.0 0.0 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU83594.1 - 2.3e-14 53.0 0.0 1.8e-13 50.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU83594.1 - 1.1e-07 31.9 1.6 2.2e-07 30.8 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EAU83594.1 - 0.097 12.2 3.1 0.41 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PAP_assoc PF03828.14 EAU83595.2 - 3.5e-07 30.0 0.0 6.3e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EAU83595.2 - 1.5e-06 28.4 0.0 2.9e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EAU83596.2 - 2.8e-06 27.1 0.0 5.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EAU83596.2 - 3e-06 27.4 0.0 4.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain MutL_C PF08676.6 EAU83597.2 - 2.3e-16 59.6 0.1 5.7e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EAU83597.2 - 1.2e-14 53.7 0.0 7.9e-08 31.7 0.0 2.4 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EAU83597.2 - 3.5e-14 52.6 0.2 8.3e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAU83597.2 - 6.5e-13 48.3 0.3 1.7e-12 47.0 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase G-alpha PF00503.15 EAU83598.2 - 8.5e-83 278.1 0.0 3.9e-77 259.5 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EAU83598.2 - 3.3e-08 32.9 0.3 9.4e-08 31.4 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Pyr_redox_2 PF07992.9 EAU83599.2 - 1e-06 28.7 0.3 4.9e-05 23.2 0.3 3.3 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU83599.2 - 4.1e-06 27.1 2.4 5.4e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2347 PF09804.4 EAU83600.2 - 1.5e-34 119.5 0.0 7.9e-34 117.2 0.0 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EAU83600.2 - 3.1e-08 32.5 0.0 0.011 14.2 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 SPA PF08616.5 EAU83600.2 - 0.00038 20.1 0.0 0.0011 18.6 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis PI-PLC-X PF00388.14 EAU83602.2 - 2.7e-39 133.8 0.0 2.5e-29 101.5 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EAU83602.2 - 1.6e-24 86.1 0.0 2.8e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EAU83602.2 - 0.077 12.8 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 C2 domain Prefoldin PF02996.12 EAU83606.1 - 6.1e-28 96.8 3.0 7.8e-28 96.5 2.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EAU83606.1 - 1.1e-05 25.0 0.4 2.2e-05 24.1 0.2 1.6 1 1 0 1 1 1 1 Prefoldin subunit COG2 PF06148.6 EAU83606.1 - 0.00041 20.2 0.5 0.45 10.3 0.1 2.1 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.15 EAU83606.1 - 0.003 17.3 7.6 0.018 14.7 0.5 2.3 2 0 0 2 2 2 1 Prefoldin subunit Baculo_PEP_C PF04513.7 EAU83606.1 - 0.011 15.6 1.5 1.2 8.9 0.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dynamitin PF04912.9 EAU83606.1 - 0.018 13.8 2.8 0.026 13.3 2.0 1.2 1 0 0 1 1 1 0 Dynamitin Mnd1 PF03962.10 EAU83606.1 - 0.02 14.5 1.8 1.4 8.5 0.1 2.0 2 0 0 2 2 2 0 Mnd1 family Spc7 PF08317.6 EAU83606.1 - 0.024 13.3 4.6 1.1 7.8 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Filament PF00038.16 EAU83606.1 - 0.039 13.4 3.1 0.34 10.3 0.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein Sec16 PF12932.2 EAU83606.1 - 0.039 13.9 0.3 0.06 13.3 0.2 1.3 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region BLOC1_2 PF10046.4 EAU83606.1 - 0.051 13.7 3.9 0.66 10.1 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.8 EAU83606.1 - 0.086 12.6 2.5 0.09 12.5 0.2 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper SYCE1 PF15233.1 EAU83606.1 - 0.092 12.6 4.3 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 CCDC155 PF14662.1 EAU83606.1 - 0.1 12.1 2.6 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF4164 PF13747.1 EAU83606.1 - 0.15 12.2 1.8 14 5.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) UPF0449 PF15136.1 EAU83606.1 - 0.18 12.0 3.6 2.7 8.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF3391 PF11871.3 EAU83606.1 - 0.2 11.8 2.5 2 8.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Laminin_II PF06009.7 EAU83606.1 - 0.26 11.0 3.9 1.1 8.9 0.3 2.1 2 0 0 2 2 2 0 Laminin Domain II TACC PF05010.9 EAU83606.1 - 0.27 10.9 3.5 0.46 10.2 2.4 1.4 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) MscS_porin PF12795.2 EAU83606.1 - 0.28 10.4 5.7 0.19 10.9 0.2 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain RasGAP_C PF03836.10 EAU83606.1 - 0.45 10.2 5.9 0.34 10.5 0.3 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DUF3091 PF11291.3 EAU83606.1 - 0.45 10.4 3.5 2.9 7.9 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3091) DUF883 PF05957.8 EAU83606.1 - 0.54 10.6 2.4 5.3 7.5 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.5 EAU83606.1 - 0.59 10.2 6.6 96 3.0 4.5 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EAU83606.1 - 0.7 7.6 5.2 3.1 5.5 0.6 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EAU83606.1 - 0.93 9.3 5.5 11 5.8 0.8 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF4200 PF13863.1 EAU83606.1 - 1.7 8.6 7.1 1.3 8.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FliJ PF02050.11 EAU83606.1 - 2.4 8.2 7.8 2 8.4 1.3 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DivIC PF04977.10 EAU83606.1 - 4.5 6.8 6.7 3.1 7.3 1.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Methyltransf_23 PF13489.1 EAU83609.1 - 4.3e-13 49.2 0.0 7.3e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU83609.1 - 1.7e-06 28.4 0.0 2.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU83609.1 - 0.00014 22.2 0.0 0.00032 21.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU83609.1 - 0.00017 22.1 0.0 0.00028 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU83609.1 - 0.00071 19.1 0.0 0.011 15.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EAU83609.1 - 0.05 12.6 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NACHT PF05729.7 EAU83610.1 - 1.1e-07 31.6 0.1 2e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU83610.1 - 0.0044 17.0 1.5 0.014 15.3 0.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EAU83610.1 - 0.0095 16.1 0.0 0.028 14.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PAP2 PF01569.16 EAU83611.1 - 3.4e-11 42.9 12.0 3.4e-11 42.9 8.3 2.8 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 EAU83611.1 - 1.4e-09 37.7 11.7 1.4e-09 37.7 8.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EAU83611.1 - 2.4 8.4 16.7 0.076 13.2 4.1 3.2 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DUF4243 PF14027.1 EAU83612.2 - 7e-99 331.3 0.0 1.1e-98 330.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3181 PF11378.3 EAU83612.2 - 0.17 11.9 0.1 0.44 10.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3181) MAGE PF01454.14 EAU83614.2 - 3.2e-33 114.7 0.0 5.5e-30 104.1 0.0 2.2 2 0 0 2 2 2 2 MAGE family Sugar_tr PF00083.19 EAU83615.1 - 1.2e-120 403.1 26.5 1.2e-120 403.1 18.4 1.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU83615.1 - 5.7e-18 64.7 41.9 1.3e-12 47.1 12.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily NACHT PF05729.7 EAU83616.1 - 4.4e-07 29.7 0.1 8.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MutS_III PF05192.13 EAU83616.1 - 0.0034 17.1 0.1 0.023 14.4 0.0 2.3 2 1 1 3 3 3 1 MutS domain III AAA PF00004.24 EAU83616.1 - 0.026 14.7 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_M36 PF02128.10 EAU83617.1 - 1e-132 442.5 5.5 2.2e-132 441.4 3.8 1.6 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EAU83617.1 - 1.6e-09 37.0 2.5 3e-09 36.1 1.8 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif DUF3782 PF12644.2 EAU83617.1 - 0.048 13.4 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) RhoGEF PF00621.15 EAU83618.1 - 2.4e-17 63.4 0.0 4.2e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Sulfate_transp PF00916.15 EAU83619.2 - 7.9e-44 149.7 2.7 7.9e-44 149.7 1.9 2.2 1 1 1 2 2 2 2 Sulfate transporter family cNMP_binding PF00027.24 EAU83619.2 - 3.3e-14 52.4 0.0 7.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EAU83619.2 - 8.6e-11 41.2 0.0 1.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain NUDIX_2 PF13869.1 EAU83620.1 - 7.7e-85 282.9 0.0 8.7e-85 282.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Ion_trans PF00520.26 EAU83622.2 - 1.3e-86 288.9 76.0 6.3e-32 110.4 8.3 6.4 6 1 0 6 6 6 4 Ion transport protein p450 PF00067.17 EAU83624.2 - 3.8e-33 114.7 0.0 5.2e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2873 PF11395.3 EAU83624.2 - 0.13 11.8 1.2 0.35 10.4 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) PCI PF01399.22 EAU83625.1 - 3.3e-09 36.9 3.4 5.4e-07 29.8 0.0 3.5 3 0 0 3 3 3 2 PCI domain GTP_EFTU PF00009.22 EAU83626.1 - 8.5e-57 191.6 0.0 1.7e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EAU83626.1 - 2e-37 127.4 0.2 1.9e-36 124.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 EAU83626.1 - 3.6e-30 103.6 0.0 7.5e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EAU83626.1 - 1.9e-21 75.7 0.1 6.9e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EAU83626.1 - 3.1e-13 49.6 0.0 7.7e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ank PF00023.25 EAU83627.2 - 2.9e-68 222.4 15.4 1.4e-06 27.8 0.0 13.5 13 0 0 13 13 13 11 Ankyrin repeat Ank_2 PF12796.2 EAU83627.2 - 1e-63 211.6 0.1 1.4e-10 41.3 0.0 8.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU83627.2 - 1.4e-53 178.3 14.9 5.6e-11 42.6 0.1 10.7 1 1 10 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU83627.2 - 4.2e-42 137.9 0.7 0.00064 19.7 0.0 12.5 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 EAU83627.2 - 8.2e-41 137.1 23.1 5.4e-07 29.6 0.2 9.3 3 2 6 10 10 10 9 Ankyrin repeats (many copies) E3_binding PF02817.12 EAU83627.2 - 0.012 15.1 4.1 0.032 13.8 0.0 3.6 5 0 0 5 5 5 0 e3 binding domain Med13_C PF06333.7 EAU83628.2 - 0.084 11.4 0.5 0.1 11.1 0.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal CBFD_NFYB_HMF PF00808.18 EAU83629.1 - 1.8e-06 27.9 0.4 3.1e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acid_PPase PF12689.2 EAU83634.1 - 1.6e-58 197.0 0.0 1.8e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EAU83634.1 - 0.035 14.3 0.4 0.84 9.8 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HTH_7 PF02796.10 EAU83634.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Defensin_3 PF08131.6 EAU83635.1 - 0.068 13.1 2.6 0.14 12.1 1.7 1.7 1 1 0 1 1 1 0 Defensin-like peptide family PepSY_2 PF13670.1 EAU83635.1 - 0.3 11.0 2.6 0.62 10.0 1.8 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Kdo PF06293.9 EAU83637.2 - 1.1e-06 27.9 0.0 3.1e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU83637.2 - 1.3e-05 25.1 0.0 0.0008 19.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EAU83637.2 - 0.00079 18.6 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 EAU83637.2 - 0.0061 15.7 0.0 0.008 15.3 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 EAU83637.2 - 0.05 12.6 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3427 PF11907.3 EAU83639.2 - 0.082 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Defensin_3 PF08131.6 EAU83640.2 - 0.024 14.6 3.3 0.05 13.5 2.1 1.7 1 1 0 1 1 1 0 Defensin-like peptide family HAMP PF00672.20 EAU83641.2 - 4.4e-35 119.6 12.8 5.6e-08 32.8 0.1 5.6 5 0 0 5 5 5 5 HAMP domain PurA PF04845.8 EAU83641.2 - 0.018 14.1 0.1 4.8 6.2 0.0 2.4 1 1 1 2 2 2 0 PurA ssDNA and RNA-binding protein DUF2365 PF10157.4 EAU83641.2 - 0.13 12.1 13.8 13 5.6 0.0 5.9 4 3 1 5 5 5 0 Uncharacterized conserved protein (DUF2365) AcylCoA_dehyd_C PF12186.3 EAU83641.2 - 0.2 11.5 7.2 17 5.3 0.0 5.3 6 2 1 7 7 7 0 Acyl-CoA dehydrogenase C terminal F-box-like PF12937.2 EAU83642.2 - 4e-08 32.8 0.1 1.5e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EAU83642.2 - 0.035 13.7 1.1 1.1 8.9 0.1 2.6 2 0 0 2 2 2 0 F-box domain CBM_1 PF00734.13 EAU83644.2 - 0.00013 21.5 3.7 0.00021 20.8 2.6 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.13 EAU83646.2 - 0.031 13.9 0.2 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 Fungal cellulose binding domain Clathrin-link PF09268.5 EAU83650.2 - 1.4 8.0 4.1 15 4.7 0.4 2.3 2 0 0 2 2 2 0 Clathrin, heavy-chain linker DUF1996 PF09362.5 EAU83652.2 - 2.2e-68 230.4 0.4 2.9e-68 230.0 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EAU83655.2 - 4.6e-65 219.5 0.6 5.6e-65 219.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF4448 PF14610.1 EAU83656.1 - 2.1e-08 33.8 0.0 2.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CENP-B_dimeris PF09026.5 EAU83656.1 - 0.0057 16.8 2.0 0.0057 16.8 1.4 1.5 2 0 0 2 2 2 1 Centromere protein B dimerisation domain GPI-anchored PF10342.4 EAU83656.1 - 0.033 14.6 0.1 0.055 13.9 0.0 1.6 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Nop14 PF04147.7 EAU83656.1 - 0.86 7.4 4.2 0.96 7.2 2.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4448 PF14610.1 EAU83657.1 - 2e-10 40.4 0.0 3.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EAU83657.1 - 0.0043 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SKG6 PF08693.5 EAU83657.1 - 0.094 12.0 0.6 0.19 11.0 0.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain F-box-like PF12937.2 EAU83662.1 - 0.00099 18.7 0.3 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU83662.1 - 0.015 14.9 0.7 0.27 10.9 0.5 2.5 1 1 0 1 1 1 0 F-box domain MtrF PF09472.5 EAU83662.1 - 0.14 11.4 0.1 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) F-box-like PF12937.2 EAU83663.2 - 9.8e-05 22.0 0.1 0.00026 20.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU83663.2 - 0.00026 20.5 2.3 0.00075 19.0 0.4 2.6 2 1 0 2 2 2 1 F-box domain TFIIB PF00382.14 EAU83664.2 - 1.3e-35 121.0 0.6 5.2e-18 64.6 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EAU83664.2 - 2.2e-21 75.8 9.4 3.7e-21 75.1 1.3 2.5 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EAU83664.2 - 1.6e-07 30.5 3.1 3.5e-07 29.4 2.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EAU83664.2 - 6.8e-07 28.9 0.2 0.0085 15.6 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.2 EAU83664.2 - 0.0049 16.6 1.8 0.01 15.6 1.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon PRA-PH PF01503.12 EAU83664.2 - 0.088 13.0 0.4 0.42 10.9 0.3 2.1 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF4237 PF14021.1 EAU83664.2 - 0.089 13.0 0.8 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4237) Ribosomal_S27e PF01667.12 EAU83664.2 - 0.15 11.5 1.4 0.32 10.5 1.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 DUF3987 PF13148.1 EAU83664.2 - 0.4 9.1 3.1 0.93 7.9 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RRN7 PF11781.3 EAU83664.2 - 1 8.8 7.4 0.25 10.8 2.7 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 TatD_DNase PF01026.16 EAU83670.1 - 3.1e-45 154.3 0.1 3.7e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EAU83670.1 - 0.0003 20.4 0.2 0.0037 16.8 0.1 2.6 1 1 0 1 1 1 1 Amidohydrolase F-box-like PF12937.2 EAU83671.1 - 0.00017 21.2 0.0 0.00039 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU83671.1 - 0.0002 20.9 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 2 F-box domain F-box PF00646.28 EAU83672.1 - 0.0057 16.2 0.6 0.051 13.2 0.1 2.7 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAU83672.1 - 0.025 14.3 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like PBP PF01161.15 EAU83673.1 - 1.1e-23 83.6 0.1 1.4e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CAP_N PF01213.14 EAU83673.1 - 0.24 10.6 2.0 0.34 10.1 1.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Prenyltrans PF00432.16 EAU83674.2 - 4.3e-38 128.5 8.4 9.4e-08 31.4 0.0 6.7 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAU83674.2 - 1.6e-21 76.7 0.0 3.7e-16 59.5 0.0 3.9 4 0 0 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAU83674.2 - 7.5e-05 22.6 0.0 0.017 15.1 0.0 3.3 2 1 2 4 4 4 3 Prenyltransferase-like Glyoxalase_2 PF12681.2 EAU83676.1 - 2.2e-10 41.1 0.0 3.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EAU83676.1 - 4.5e-07 29.8 0.0 5.2e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EAU83676.1 - 0.07 13.1 0.0 0.22 11.5 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Saccharop_dh PF03435.13 EAU83678.1 - 2.5e-119 398.7 0.8 4.8e-119 397.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 EAU83678.1 - 8.9e-89 296.6 0.0 1.4e-88 295.9 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 EAU83678.1 - 1.7e-08 34.6 1.3 6.5e-07 29.5 0.0 2.7 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EAU83678.1 - 1.2e-05 25.8 0.0 5.1e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU83678.1 - 4.9e-05 23.3 0.0 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU83678.1 - 0.00012 21.7 0.0 0.00032 20.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 EAU83678.1 - 0.00032 20.7 0.3 0.00079 19.4 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 EAU83678.1 - 0.0004 20.7 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Methyltransf_12 PF08242.7 EAU83678.1 - 0.0057 17.1 0.1 0.064 13.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAU83678.1 - 0.012 14.9 0.0 0.12 11.6 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase small domain Semialdhyde_dh PF01118.19 EAU83678.1 - 0.017 15.4 0.8 0.025 14.9 0.0 1.7 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EAU83678.1 - 0.018 15.5 0.1 0.095 13.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Pterin_bind PF00809.17 EAU83678.1 - 0.023 14.0 0.5 0.68 9.2 0.4 2.4 1 1 0 1 1 1 0 Pterin binding enzyme NAD_binding_3 PF03447.11 EAU83678.1 - 0.064 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 EAU83678.1 - 0.082 13.4 0.0 2.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain ThuA PF06283.6 EAU83679.2 - 0.058 13.0 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Trehalose utilisation F-box-like PF12937.2 EAU83680.1 - 3.6e-05 23.3 0.3 8.7e-05 22.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like Tet_JBP PF12851.2 EAU83685.2 - 4.3e-14 52.1 0.0 6.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily CHASE3 PF05227.8 EAU83688.1 - 0.00038 20.1 1.2 0.0016 18.1 0.2 2.4 1 1 1 2 2 2 1 CHASE3 domain Baculo_PEP_C PF04513.7 EAU83688.1 - 0.00064 19.5 0.8 0.031 14.0 0.0 3.0 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Macoilin PF09726.4 EAU83688.1 - 0.0055 15.0 4.0 0.0062 14.8 0.0 2.1 2 0 0 2 2 2 1 Transmembrane protein EzrA PF06160.7 EAU83688.1 - 0.0058 14.8 0.9 0.0094 14.1 0.6 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EAU83688.1 - 0.007 15.5 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Filament PF00038.16 EAU83688.1 - 0.019 14.4 0.1 0.019 14.4 0.1 1.7 2 0 0 2 2 2 0 Intermediate filament protein COG2 PF06148.6 EAU83688.1 - 0.03 14.1 0.1 0.15 11.9 0.0 2.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 EAU83688.1 - 0.037 13.9 0.3 2.7 7.9 0.0 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EAU83688.1 - 0.048 13.4 2.6 0.93 9.3 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 EAU83688.1 - 0.055 13.0 0.1 0.055 13.0 0.1 2.3 2 1 0 2 2 2 0 IncA protein MscS_porin PF12795.2 EAU83688.1 - 0.057 12.7 0.1 0.057 12.7 0.1 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TBPIP PF07106.8 EAU83688.1 - 0.071 12.6 0.4 0.29 10.6 0.0 2.1 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EAU83688.1 - 0.1 11.2 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EAU83688.1 - 0.11 12.3 1.6 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EAU83688.1 - 0.11 10.9 0.4 0.26 9.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain Herpes_U30 PF04523.8 EAU83688.1 - 0.12 9.8 0.1 0.25 8.7 0.1 1.4 1 0 0 1 1 1 0 Herpes virus tegument protein U30 FAM104 PF15434.1 EAU83688.1 - 0.39 10.9 4.7 0.2 11.8 0.9 2.2 2 0 0 2 2 2 0 Family 104 Mucin PF01456.12 EAU83688.1 - 1.3 8.8 27.4 0.026 14.2 14.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein F-box-like PF12937.2 EAU83693.1 - 0.00031 20.4 0.5 0.00075 19.1 0.1 1.9 2 0 0 2 2 2 1 F-box-like HMG_box PF00505.14 EAU83694.1 - 2.6e-08 33.9 0.0 6.7e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box Tyrosinase PF00264.15 EAU83695.1 - 1.7e-40 139.5 0.0 2.3e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Asp-Al_Ex PF06826.7 EAU83696.1 - 0.0029 17.1 0.1 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Predicted Permease Membrane Region FPN1 PF06963.7 EAU83698.2 - 0.65 8.3 0.1 0.98 7.7 0.1 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) CaM_binding PF07839.6 EAU83699.2 - 0.079 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Plant calmodulin-binding domain Ion_trans_2 PF07885.11 EAU83700.2 - 9.6e-23 79.7 30.4 1.4e-14 53.5 6.2 2.7 3 0 0 3 3 3 2 Ion channel Flp_Fap PF04964.9 EAU83703.2 - 0.34 10.5 3.4 18 5.0 0.0 3.2 3 0 0 3 3 3 0 Flp/Fap pilin component UQ_con PF00179.21 EAU83704.2 - 6.9e-08 32.0 0.0 1.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PARP PF00644.15 EAU83704.2 - 1.3e-05 24.6 0.0 4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain AMP-binding PF00501.23 EAU83705.2 - 2.3e-41 141.5 0.0 2.7e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU83705.2 - 2.3e-12 47.6 0.0 5.7e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EAU83706.1 - 1.3e-25 89.7 0.0 1.9e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CCT_2 PF09425.5 EAU83707.1 - 0.0087 15.5 2.1 0.023 14.2 1.4 1.7 1 0 0 1 1 1 1 Divergent CCT motif LRR_4 PF12799.2 EAU83707.1 - 0.21 11.2 6.7 1.7 8.3 1.4 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAU83707.1 - 1.6 9.0 5.3 25 5.3 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.2 EAU83709.1 - 6.4e-06 25.8 2.3 1.5e-05 24.5 1.6 1.7 1 0 0 1 1 1 1 F-box-like Protoglobin PF11563.3 EAU83711.1 - 1.9e-50 170.5 0.1 2.3e-50 170.3 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Sugar_tr PF00083.19 EAU83712.1 - 7e-106 354.5 20.0 8e-106 354.3 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU83712.1 - 2.3e-21 75.9 24.6 2.3e-21 75.9 17.1 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.2 EAU83713.1 - 5.1e-05 22.9 0.8 0.00033 20.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU83713.1 - 0.024 14.2 0.1 0.096 12.3 0.1 2.0 2 0 0 2 2 2 0 F-box domain WD40 PF00400.27 EAU83715.2 - 8.9e-49 161.7 17.6 3.4e-11 42.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EAU83715.2 - 3.4e-05 23.6 13.7 0.62 9.7 0.9 4.4 2 2 2 4 4 4 4 Transcription factor IIIC subunit delta N-term p450 PF00067.17 EAU83716.2 - 2.9e-54 184.3 0.0 4.1e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 EAU83718.1 - 1.2e-14 54.1 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU83718.1 - 2.9e-14 53.1 0.0 4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU83718.1 - 2.8e-11 43.7 0.0 5.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU83718.1 - 4.4e-11 43.3 0.0 8.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU83718.1 - 1.1e-09 38.5 0.0 1.9e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAU83718.1 - 6.9e-07 29.0 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EAU83718.1 - 9.4e-07 28.1 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Sterol_MT_C PF08498.5 EAU83718.1 - 9.7e-07 28.6 0.0 2.7e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Sterol methyltransferase C-terminal CMAS PF02353.15 EAU83718.1 - 8.3e-06 25.0 0.0 9.9e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EAU83718.1 - 0.00011 22.5 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EAU83718.1 - 0.00055 19.3 0.0 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EAU83718.1 - 0.012 15.6 0.1 0.076 13.0 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EAU83718.1 - 0.07 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EAU83718.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 EAU83718.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF3321 PF11968.3 EAU83718.1 - 0.17 11.4 0.0 1.5 8.4 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase (DUF3321) p450 PF00067.17 EAU83724.2 - 1.1e-15 57.1 0.1 3.3e-15 55.5 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 PIG-P PF08510.7 EAU83725.2 - 0.035 13.7 1.4 2 8.0 0.1 2.2 2 0 0 2 2 2 0 PIG-P Pkinase PF00069.20 EAU83726.1 - 2.6e-19 69.3 0.0 1.3e-11 44.1 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU83726.1 - 3.3e-06 26.3 0.2 0.0015 17.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase AFOR_C PF01314.13 EAU83726.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 F-box-like PF12937.2 EAU83727.2 - 1.7e-06 27.6 1.2 1.6e-05 24.5 0.6 2.6 2 0 0 2 2 2 1 F-box-like Na_H_Exchanger PF00999.16 EAU83728.2 - 1.5e-63 214.5 48.5 2.2e-63 214.1 33.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PCNA_N PF00705.13 EAU83729.1 - 2.5e-52 175.6 2.0 1.4e-51 173.3 1.7 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EAU83729.1 - 2.6e-42 143.7 0.1 2.7e-20 72.5 0.0 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EAU83729.1 - 3.3e-05 23.1 0.0 0.00018 20.7 0.0 1.9 2 0 0 2 2 2 1 Rad9 SDA1 PF05285.7 EAU83729.1 - 0.034 13.4 27.0 0.049 12.9 18.7 1.1 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 EAU83729.1 - 0.064 12.4 15.8 0.084 12.1 10.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Daxx PF03344.10 EAU83729.1 - 0.12 10.7 22.6 0.18 10.2 15.7 1.2 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 EAU83729.1 - 0.98 8.9 31.0 1.6 8.2 21.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EAU83729.1 - 1.4 6.7 34.3 1.5 6.6 23.3 1.3 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.5 EAU83729.1 - 2.7 6.9 32.2 3.8 6.4 22.3 1.1 1 0 0 1 1 1 0 BUD22 DUF2360 PF10152.4 EAU83730.1 - 2.6 8.3 12.3 0.034 14.4 0.7 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Tyrosinase PF00264.15 EAU83732.2 - 5.7e-38 131.3 0.0 7.6e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase WD40 PF00400.27 EAU83733.2 - 0.0015 18.3 0.2 0.015 15.1 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat F-box-like PF12937.2 EAU83733.2 - 0.0033 17.1 0.2 0.0093 15.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU83733.2 - 0.0064 16.1 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain Pap_E4 PF02711.9 EAU83735.2 - 2.2 9.1 5.6 1.3 9.8 0.2 2.2 1 1 1 2 2 2 0 E4 protein DUF2615 PF11027.3 EAU83741.2 - 0.59 10.0 0.0 0.59 10.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) UPF0444 PF15475.1 EAU83743.1 - 1.2 9.2 4.2 1.3 9.0 2.1 1.8 1 1 1 2 2 2 0 Transmembrane protein C12orf23, UPF0444 DUF605 PF04652.11 EAU83744.1 - 6.4 6.0 18.8 8.1 5.7 13.1 1.2 1 0 0 1 1 1 0 Vta1 like TMEM154 PF15102.1 EAU83745.1 - 6.6e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EAU83745.1 - 0.0062 14.8 0.0 0.011 13.9 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E GRP PF07172.6 EAU83745.1 - 0.01 16.3 13.1 0.01 16.3 9.1 5.3 6 0 0 6 6 6 2 Glycine rich protein family CD34_antigen PF06365.7 EAU83745.1 - 0.25 10.9 0.0 0.41 10.2 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Tweety PF04906.8 EAU83745.1 - 0.32 9.3 0.0 0.45 8.8 0.0 1.1 1 0 0 1 1 1 0 Tweety DUF1180 PF06679.7 EAU83745.1 - 4.3 7.1 6.9 1.1e+02 2.5 4.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) ENTH PF01417.15 EAU83746.1 - 4.8e-51 171.8 0.3 1.3e-50 170.3 0.0 2.0 2 0 0 2 2 2 1 ENTH domain DUF1720 PF08226.6 EAU83746.1 - 7.5 6.6 95.1 12 6.0 3.5 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1720) Polysacc_deac_1 PF01522.16 EAU83747.2 - 2e-06 27.4 0.0 5.1e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.20 EAU83748.2 - 3.2e-29 101.8 0.0 4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU83748.2 - 2.8e-22 79.0 0.0 4.3e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU83748.2 - 1.1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EAU83748.2 - 0.0077 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Selenoprotein_S PF06936.6 EAU83749.1 - 2.2 7.7 9.9 4.9 6.6 6.9 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) RNA_Me_trans PF04252.8 EAU83755.1 - 8.9e-34 116.6 0.0 1.2e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Glyco_hydro_10 PF00331.15 EAU83756.2 - 2.5e-27 95.7 0.0 1.9e-14 53.4 0.0 2.2 2 1 0 2 2 2 2 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 EAU83756.2 - 0.018 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Usp PF00582.21 EAU83757.1 - 4.7e-16 59.2 0.0 7.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family JAB PF01398.16 EAU83758.2 - 2.6e-15 56.1 0.7 8.8e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EAU83758.2 - 2.8e-09 36.9 0.0 7.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EAU83758.2 - 1.7e-07 30.7 0.0 1.7e-07 30.7 0.0 3.1 3 1 0 3 3 3 1 Prokaryotic homologs of the JAB domain DUF357 PF04010.8 EAU83758.2 - 0.00024 20.7 0.1 0.00049 19.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF357) NPL4 PF05021.10 EAU83758.2 - 0.11 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 NPL4 family F-box-like PF12937.2 EAU83760.2 - 1.5e-06 27.8 0.1 3.1e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like N2227 PF07942.7 EAU83761.2 - 3.1e-97 324.7 0.0 3.7e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EAU83761.2 - 3.9e-06 26.6 0.0 9.3e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU83761.2 - 0.0021 18.4 0.0 0.0094 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FRG2 PF15315.1 EAU83761.2 - 0.1 12.5 0.4 0.16 11.9 0.3 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Zip PF02535.17 EAU83761.2 - 1.5 7.7 4.6 2.2 7.2 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EAU83761.2 - 6.9 5.9 9.9 11 5.3 6.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Isy1 PF06246.7 EAU83762.2 - 1.5e-79 266.9 6.5 3.4e-79 265.8 4.5 1.5 1 1 0 1 1 1 1 Isy1-like splicing family P22_Tail-4 PF11650.3 EAU83762.2 - 0.048 13.2 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 P22 tail accessory factor UbiA PF01040.13 EAU83763.2 - 2.2e-24 86.0 15.9 3.4e-24 85.4 11.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Ferric_reduct PF01794.14 EAU83763.2 - 0.012 15.7 3.1 0.24 11.4 2.5 2.3 1 1 1 2 2 2 0 Ferric reductase like transmembrane component LRR_8 PF13855.1 EAU83764.2 - 0.0051 16.5 0.4 0.03 14.0 0.1 2.5 2 0 0 2 2 2 1 Leucine rich repeat Ribosomal_L31e PF01198.14 EAU83765.1 - 7.3e-36 121.6 1.2 9.1e-36 121.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CFEM PF05730.6 EAU83766.1 - 2.1e-10 40.2 9.0 3.1e-10 39.7 6.2 1.2 1 0 0 1 1 1 1 CFEM domain Serglycin PF04360.7 EAU83766.1 - 0.012 15.3 0.7 0.014 15.1 0.5 1.1 1 0 0 1 1 1 0 Serglycin HsdM_N PF12161.3 EAU83767.1 - 0.051 13.9 1.2 0.11 12.9 0.8 1.5 1 0 0 1 1 1 0 HsdM N-terminal domain eIF3_subunit PF08597.5 EAU83767.1 - 0.68 9.4 12.9 1.8 8.0 8.9 1.7 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RNase_H2-Ydr279 PF09468.5 EAU83767.1 - 2.4 7.2 7.7 4.4 6.3 5.3 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3306 PF11748.3 EAU83767.1 - 4.4 8.0 14.1 0.58 10.8 5.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Vfa1 PF08432.5 EAU83767.1 - 6.7 6.7 13.5 3.4 7.6 7.8 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ank_2 PF12796.2 EAU83768.2 - 3.2e-161 524.1 44.3 9.5e-19 67.5 0.0 13.8 1 1 16 17 17 17 17 Ankyrin repeats (3 copies) Ank PF00023.25 EAU83768.2 - 4.8e-140 448.9 49.7 7.3e-09 34.9 0.0 23.5 23 1 0 23 23 23 21 Ankyrin repeat Ank_4 PF13637.1 EAU83768.2 - 3e-97 317.4 24.1 4.5e-10 39.7 0.0 19.5 3 3 19 22 22 22 22 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU83768.2 - 5.6e-88 279.9 2.9 0.0001 22.2 0.0 22.4 22 0 0 22 22 22 17 Ankyrin repeat Ank_5 PF13857.1 EAU83768.2 - 2.9e-82 268.8 42.9 1.3e-08 34.8 0.2 16.7 3 2 15 20 20 20 17 Ankyrin repeats (many copies) DUF3890 PF13029.1 EAU83768.2 - 2.2e-05 24.4 1.5 7.9 6.6 0.0 7.4 7 1 1 8 8 8 1 Domain of unknown function (DUF3890) HHH_3 PF12836.2 EAU83768.2 - 0.02 14.8 7.9 1.3e+02 2.5 0.0 7.6 10 0 0 10 10 10 0 Helix-hairpin-helix motif NACHT PF05729.7 EAU83768.2 - 0.025 14.2 0.1 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EAU83768.2 - 0.049 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 EAU83768.2 - 0.054 13.6 0.1 0.27 11.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain Phosphonate-bd PF12974.2 EAU83768.2 - 0.092 12.1 1.0 0.88 8.9 0.0 2.8 2 1 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Clp_N PF02861.15 EAU83768.2 - 0.57 10.1 13.6 11 6.0 0.0 8.6 11 0 0 11 11 11 0 Clp amino terminal domain Clathrin_bdg PF15045.1 EAU83768.2 - 0.63 9.5 4.5 9.3 5.8 0.0 5.0 5 2 2 7 7 7 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Hydrolase_like PF13242.1 EAU83768.2 - 1.7 8.4 7.1 14 5.4 0.0 4.7 5 0 0 5 5 5 0 HAD-hyrolase-like MFS_1 PF07690.11 EAU83773.2 - 2.3e-39 135.0 15.8 3.5e-39 134.5 10.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MerC PF03203.9 EAU83773.2 - 1.1 9.6 8.3 2.4 8.5 1.0 3.4 2 2 0 2 2 2 0 MerC mercury resistance protein NHL PF01436.16 EAU83775.2 - 0.00053 19.7 1.2 0.47 10.5 0.0 4.0 5 0 0 5 5 5 1 NHL repeat SGL PF08450.7 EAU83775.2 - 0.0012 18.2 0.1 0.3 10.4 0.1 2.6 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 EAU83775.2 - 0.04 13.5 0.1 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SBBP PF06739.6 EAU83775.2 - 0.14 11.9 1.5 0.39 10.5 0.1 2.6 2 0 0 2 2 2 0 Beta-propeller repeat Arylesterase PF01731.15 EAU83775.2 - 0.16 11.9 0.0 28 4.7 0.0 3.1 3 0 0 3 3 3 0 Arylesterase Hemerythrin PF01814.18 EAU83776.2 - 5.8e-05 23.2 0.1 0.0005 20.2 0.1 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain WW PF00397.21 EAU83777.1 - 3.3e-06 26.8 4.3 3.3e-06 26.8 3.0 1.9 2 0 0 2 2 2 1 WW domain DHHW PF14286.1 EAU83777.1 - 5.8 6.1 7.4 8.7 5.5 5.1 1.4 1 0 0 1 1 1 0 DHHW protein Macoilin PF09726.4 EAU83777.1 - 5.8 5.0 12.0 7.6 4.6 8.3 1.3 1 0 0 1 1 1 0 Transmembrane protein FHA PF00498.21 EAU83778.2 - 3e-05 24.0 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain CAP59_mtransfer PF11735.3 EAU83779.1 - 3.7e-72 242.4 0.0 5.1e-72 242.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Nop53 PF07767.6 EAU83781.2 - 2.3e-84 283.6 24.7 2.3e-84 283.6 17.1 1.6 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.7 EAU83781.2 - 8.4 6.0 13.9 9.6 5.8 5.3 2.8 2 1 0 2 2 2 0 BOP1NT (NUC169) domain Ank PF00023.25 EAU83782.2 - 6.3e-87 281.3 18.7 1.5e-07 30.8 0.0 15.7 15 0 0 15 15 15 14 Ankyrin repeat Ank_2 PF12796.2 EAU83782.2 - 1.8e-72 239.7 6.3 4.3e-15 55.8 0.3 9.5 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU83782.2 - 4.3e-65 214.2 21.1 5.3e-09 36.0 0.1 10.9 6 4 3 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU83782.2 - 1.1e-49 161.3 0.0 0.00011 22.1 0.0 15.6 15 0 0 15 15 15 11 Ankyrin repeat Ank_4 PF13637.1 EAU83782.2 - 6.7e-44 147.5 12.4 1.5e-08 34.9 0.0 12.8 2 1 12 14 14 14 13 Ankyrin repeats (many copies) HHH_5 PF14520.1 EAU83782.2 - 2.5e-05 24.3 0.4 17 5.6 0.0 7.1 5 2 1 6 6 6 1 Helix-hairpin-helix domain RPN7 PF10602.4 EAU83783.2 - 4.5e-43 146.6 2.0 6.6e-43 146.1 1.4 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EAU83783.2 - 3.7e-15 56.1 0.6 1e-14 54.6 0.1 2.0 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EAU83783.2 - 1.1e-05 24.9 0.1 0.34 10.9 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU83783.2 - 0.0006 19.7 0.1 0.12 12.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU83783.2 - 0.0022 17.6 0.0 1.1 9.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat dsDNA_bind PF01984.15 EAU83783.2 - 0.0037 17.2 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI_Csn8 PF10075.4 EAU83783.2 - 0.0055 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_11 PF13414.1 EAU83783.2 - 0.0059 16.2 2.6 0.54 9.9 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 EAU83783.2 - 0.0071 16.0 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU83783.2 - 0.016 14.7 0.3 9 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU83783.2 - 0.04 13.8 0.1 0.59 10.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.1 EAU83783.2 - 0.051 13.6 0.1 0.051 13.6 0.1 3.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAU83783.2 - 0.31 11.7 4.6 14 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EAU83784.1 - 1.1e-37 129.5 13.9 1.8e-37 128.9 9.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.14 EAU83784.1 - 0.052 13.0 6.5 0.27 10.7 0.2 2.9 2 1 1 3 3 3 0 VIT family MerC PF03203.9 EAU83784.1 - 9.4 6.6 10.0 3.3 8.1 0.9 3.6 2 2 0 2 2 2 0 MerC mercury resistance protein CHAT PF12770.2 EAU83785.2 - 3.5e-27 95.2 0.0 5.8e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.1 EAU83785.2 - 8.3e-23 79.5 0.9 0.03 14.2 0.0 9.4 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EAU83785.2 - 1e-21 76.6 8.9 0.0036 17.1 0.2 8.8 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EAU83785.2 - 7.4e-10 38.2 3.4 0.93 9.8 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat AAA_10 PF12846.2 EAU83785.2 - 0.0042 16.5 0.9 1.5 8.1 0.2 3.5 3 1 0 3 3 3 1 AAA-like domain DUF520 PF04461.8 EAU83785.2 - 0.13 12.1 0.1 61 3.4 0.0 4.4 6 0 0 6 6 6 0 Protein of unknown function (DUF520) TPR_1 PF00515.23 EAU83785.2 - 1 9.0 15.0 58 3.5 0.1 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat SET PF00856.23 EAU83786.1 - 9.6e-12 45.5 0.0 1.6e-10 41.5 0.0 2.4 1 1 0 1 1 1 1 SET domain SET PF00856.23 EAU83787.2 - 1.8e-12 47.8 0.1 1.1e-10 42.0 0.0 2.8 2 1 0 2 2 2 1 SET domain Ank_2 PF12796.2 EAU83788.1 - 3.4e-34 117.0 5.6 1.7e-13 50.6 0.4 7.0 2 1 6 8 8 8 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU83788.1 - 3.1e-32 109.8 14.2 7.5e-09 35.5 0.2 7.0 4 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU83788.1 - 2.3e-31 107.5 5.2 2.7e-09 37.2 0.1 7.7 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU83788.1 - 2.1e-27 92.4 4.4 1.9e-05 24.4 0.0 9.2 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.25 EAU83788.1 - 6.2e-24 82.5 17.6 0.00015 21.3 0.0 9.5 9 1 0 9 9 9 6 Ankyrin repeat AAA_22 PF13401.1 EAU83788.1 - 2.8e-06 27.4 0.0 1.6e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAU83788.1 - 0.00011 21.9 0.0 0.00029 20.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU83788.1 - 0.00013 22.0 0.2 0.00068 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAU83788.1 - 0.00041 19.3 0.0 0.011 14.5 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EAU83788.1 - 0.042 13.5 0.1 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 EAU83788.1 - 0.046 12.6 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EAU83788.1 - 0.095 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Ank_5 PF13857.1 EAU83789.2 - 4.2e-29 99.8 11.8 1.2e-08 34.9 0.5 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU83789.2 - 1e-26 93.0 5.7 4.8e-05 23.6 0.0 5.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAU83789.2 - 4.3e-23 79.0 4.5 0.00023 21.0 0.0 8.4 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EAU83789.2 - 3.3e-19 68.8 9.9 2.6e-06 27.7 0.2 7.4 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 EAU83789.2 - 2.4e-18 64.9 12.4 0.005 16.5 0.1 7.6 7 1 0 7 7 7 5 Ankyrin repeat AAA_22 PF13401.1 EAU83789.2 - 2.1e-05 24.6 0.0 5.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU83789.2 - 0.00014 21.9 0.8 0.00095 19.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EAU83789.2 - 0.00021 20.9 0.0 0.00059 19.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EAU83789.2 - 0.036 12.9 0.0 0.093 11.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 EAU83789.2 - 0.088 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.2 EAU83790.1 - 3.8e-35 120.0 3.3 2.2e-11 43.9 0.1 5.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU83790.1 - 6.4e-29 99.3 5.2 1.5e-06 28.2 0.1 7.5 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU83790.1 - 1.8e-26 92.0 2.4 1.1e-05 25.7 0.0 7.2 2 2 6 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.25 EAU83790.1 - 2.4e-25 87.0 13.7 4.5e-05 23.0 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.1 EAU83790.1 - 4.9e-24 82.0 3.7 0.00029 20.7 0.0 9.1 9 0 0 9 9 9 5 Ankyrin repeat AAA_22 PF13401.1 EAU83790.1 - 2e-05 24.7 0.0 7.1e-05 22.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EAU83790.1 - 2.7e-05 24.2 0.1 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EAU83790.1 - 6.7e-05 22.5 0.0 0.0002 21.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EAU83790.1 - 0.0008 18.3 0.0 0.0073 15.2 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain HTH_12 PF08461.5 EAU83790.1 - 0.014 15.1 0.6 0.048 13.3 0.4 1.9 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain DUF2075 PF09848.4 EAU83790.1 - 0.054 12.4 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EAU83790.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 EAU83790.1 - 0.15 11.7 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase Ank_2 PF12796.2 EAU83791.1 - 1.6e-31 108.5 7.3 8e-13 48.5 0.2 5.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU83791.1 - 3.5e-27 93.8 5.0 4.4e-06 26.7 0.1 7.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU83791.1 - 2e-23 82.2 0.9 9.5e-08 32.3 0.1 7.5 4 2 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.25 EAU83791.1 - 3.7e-23 80.1 8.7 7.1e-05 22.4 0.0 7.4 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EAU83791.1 - 2.1e-21 73.8 1.1 0.00021 21.1 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat AAA_22 PF13401.1 EAU83791.1 - 1.7e-05 24.9 0.0 6.7e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU83791.1 - 0.00053 20.0 0.1 0.0036 17.3 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EAU83791.1 - 0.00091 18.9 0.0 0.0027 17.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EAU83791.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EAU83791.1 - 0.026 13.5 0.0 0.057 12.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Choline_kinase PF01633.15 EAU83792.2 - 0.07 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aminotran_1_2 PF00155.16 EAU83793.1 - 1.8e-39 135.7 0.0 2.2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EAU83793.1 - 0.013 13.7 0.0 0.022 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HTH_11 PF08279.7 EAU83793.1 - 0.05 13.2 0.1 0.15 11.6 0.1 1.8 1 0 0 1 1 1 0 HTH domain Con-6 PF10346.4 EAU83796.2 - 0.0046 16.3 0.1 0.0071 15.7 0.1 1.3 1 0 0 1 1 1 1 Conidiation protein 6 Ank_2 PF12796.2 EAU83797.2 - 5.4e-38 129.2 5.9 2.3e-14 53.5 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU83797.2 - 3.6e-29 100.1 8.1 2.8e-10 40.0 0.3 7.3 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU83797.2 - 9e-29 99.3 3.5 9.5e-08 32.3 0.0 7.1 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.25 EAU83797.2 - 1e-27 94.4 5.1 9.3e-06 25.2 0.0 8.4 7 1 1 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 EAU83797.2 - 5.2e-26 88.1 4.1 0.00016 21.5 0.0 8.8 10 0 0 10 10 10 5 Ankyrin repeat AAA_22 PF13401.1 EAU83797.2 - 2e-05 24.7 0.0 5.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAU83797.2 - 4.1e-05 23.3 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU83797.2 - 0.00012 22.1 0.4 0.0004 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAU83797.2 - 0.011 14.6 0.0 0.029 13.2 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 EAU83797.2 - 0.035 13.0 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Con-6 PF10346.4 EAU83798.2 - 2.5e-17 61.9 0.4 4.4e-17 61.1 0.3 1.4 1 0 0 1 1 1 1 Conidiation protein 6 TIMELESS PF04821.9 EAU83799.2 - 6.4e-53 179.6 0.5 6.4e-53 179.6 0.3 2.1 2 0 0 2 2 2 1 Timeless protein RNA_pol_Rpb4 PF03874.11 EAU83799.2 - 3.4 7.7 6.8 8.2 6.4 0.0 3.6 4 0 0 4 4 4 0 RNA polymerase Rpb4 bZIP_1 PF00170.16 EAU83801.2 - 8.5e-05 22.4 8.6 0.0027 17.6 2.7 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EAU83801.2 - 0.00012 21.8 10.3 0.0023 17.7 1.5 2.3 2 0 0 2 2 2 2 Basic region leucine zipper MAD PF05557.8 EAU83801.2 - 0.01 13.9 0.4 0.016 13.3 0.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Lzipper-MIP1 PF14389.1 EAU83801.2 - 0.011 15.7 0.2 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GOLGA2L5 PF15070.1 EAU83801.2 - 0.026 13.0 2.3 0.034 12.6 1.6 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 TMF_DNA_bd PF12329.3 EAU83801.2 - 0.062 13.1 1.7 0.36 10.6 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 EAU83801.2 - 0.074 12.7 1.4 0.12 12.0 0.3 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF641 PF04859.7 EAU83801.2 - 0.074 12.8 1.1 0.16 11.7 0.5 1.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 EAU83801.2 - 0.089 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 EAU83801.2 - 0.17 11.8 3.1 8.7 6.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.10 EAU83801.2 - 0.29 10.6 3.8 0.92 9.0 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator Wbp11 PF09429.5 EAU83801.2 - 0.32 10.9 4.4 7.9 6.5 1.1 2.3 2 0 0 2 2 2 0 WW domain binding protein 11 Med9 PF07544.8 EAU83801.2 - 0.4 10.4 3.7 9.2 6.0 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Atg14 PF10186.4 EAU83801.2 - 0.43 9.4 3.8 7 5.5 0.4 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 EAU83801.2 - 1.5 8.6 5.8 7.5 6.3 4.0 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) OPA3 PF07047.7 EAU83801.2 - 1.9 8.3 4.3 1.5 8.6 0.3 2.0 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) SlyX PF04102.7 EAU83801.2 - 3.4 8.1 7.8 3.8 7.9 1.8 3.1 2 1 1 3 3 3 0 SlyX Transaldolase PF00923.14 EAU83802.2 - 3.5e-25 88.7 0.0 4.5e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Transaldolase DUF639 PF04842.7 EAU83802.2 - 0.014 13.5 0.0 0.021 12.9 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3343 PF11823.3 EAU83802.2 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Hydrolase_6 PF13344.1 EAU83803.1 - 3.8e-31 106.9 0.0 7.8e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU83803.1 - 5.5e-16 58.0 0.0 1.3e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EAU83803.1 - 9.6e-12 45.7 0.0 1.3e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAU83803.1 - 9.1e-07 29.2 0.2 0.00029 21.1 0.1 2.9 3 1 0 3 3 3 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EAU83803.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Ribosomal_L7Ae PF01248.21 EAU83803.1 - 0.086 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PIG-F PF06699.6 EAU83804.1 - 3.3e-30 105.4 8.1 3.5e-30 105.3 4.2 1.8 1 1 1 2 2 2 1 GPI biosynthesis protein family Pig-F Ribosomal_L34e PF01199.13 EAU83805.1 - 1.1e-38 131.3 3.2 1.6e-38 130.7 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.3 EAU83805.1 - 1.1 8.9 4.7 7.2 6.3 0.2 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain DUF89 PF01937.14 EAU83809.2 - 1.2e-103 346.6 0.0 1.5e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Con-6 PF10346.4 EAU83811.2 - 9.3e-11 40.9 1.6 9.7e-10 37.6 1.1 2.2 1 1 0 1 1 1 1 Conidiation protein 6 Cation_efflux PF01545.16 EAU83814.1 - 5.2e-10 38.8 0.6 1.3e-09 37.5 0.2 1.7 1 1 0 1 1 1 1 Cation efflux family Lipase_3 PF01764.20 EAU83815.2 - 1e-15 57.5 0.1 3.5e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Prothymosin PF03247.9 EAU83822.1 - 0.017 15.2 2.1 0.043 13.9 1.5 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family TMEM173 PF15009.1 EAU83822.1 - 0.081 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 173 zf-HC2 PF13490.1 EAU83826.2 - 0.19 11.6 2.6 9.5 6.2 0.2 2.6 2 0 0 2 2 2 0 Putative zinc-finger SOG2 PF10428.4 EAU83826.2 - 1.2 7.7 11.2 0.073 11.7 1.6 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein MFS_1 PF07690.11 EAU83827.2 - 2e-27 95.8 25.2 2.9e-27 95.3 17.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2929 PF11151.3 EAU83827.2 - 0.024 14.7 0.2 0.34 11.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) EutH PF04346.7 EAU83827.2 - 2.5 6.9 11.3 0.083 11.8 2.8 2.0 2 1 0 2 2 2 0 Ethanolamine utilisation protein, EutH eIF-5_eIF-2B PF01873.12 EAU83828.2 - 8.5e-44 148.2 0.2 1.3e-43 147.5 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EAU83828.2 - 0.022 14.0 0.1 0.042 13.1 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding zf-HYPF PF07503.7 EAU83828.2 - 0.034 13.5 0.1 8.3 5.9 0.0 2.5 2 0 0 2 2 2 0 HypF finger IF2_N PF04760.10 EAU83828.2 - 0.039 13.6 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Arc_trans_TRASH PF08394.5 EAU83828.2 - 1.8 8.7 4.7 11 6.2 0.0 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain NT-C2 PF10358.4 EAU83829.1 - 3.2e-13 49.4 0.0 5.4e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins F-box-like PF12937.2 EAU83831.1 - 0.0091 15.7 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU83831.1 - 0.028 14.0 4.9 27 4.5 0.2 5.3 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EAU83832.1 - 3.3e-05 23.4 7.5 0.00012 21.7 3.9 2.8 2 1 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EAU83832.1 - 0.072 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain V-ATPase_H_C PF11698.3 EAU83832.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H F-box PF00646.28 EAU83832.1 - 6.3 6.5 9.3 6.3 6.5 0.2 4.1 5 0 0 5 5 5 0 F-box domain MFS_1 PF07690.11 EAU83833.2 - 4e-16 58.6 44.1 1.1e-12 47.3 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAU83833.2 - 9.9e-05 20.9 24.0 0.0016 16.9 4.3 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Hydrophobin PF01185.13 EAU83834.1 - 8.9e-18 64.5 12.1 1.1e-17 64.2 8.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ribosomal_L27e PF01777.13 EAU83835.1 - 2.3e-36 123.7 2.6 3.5e-36 123.2 1.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EAU83835.1 - 0.0057 16.3 0.3 0.014 15.0 0.2 1.8 1 0 0 1 1 1 1 KOW motif SUI1 PF01253.17 EAU83835.1 - 0.065 13.0 1.9 0.23 11.2 0.4 2.3 2 1 0 2 2 2 0 Translation initiation factor SUI1 Nucleoporin_FG PF13634.1 EAU83836.1 - 2e-31 108.5 170.3 3.2e-14 53.1 31.8 4.6 1 1 3 4 4 4 4 Nucleoporin FG repeat region Nup54 PF13874.1 EAU83836.1 - 2e-26 92.3 0.2 2e-26 92.3 0.2 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 HWE_HK PF07536.9 EAU83836.1 - 0.048 14.1 1.4 0.048 14.1 1.0 1.8 2 0 0 2 2 2 0 HWE histidine kinase TPR_10 PF13374.1 EAU83838.2 - 3.8e-43 144.2 12.3 0.00051 19.8 0.0 12.3 11 1 1 12 12 12 10 Tetratricopeptide repeat TPR_12 PF13424.1 EAU83838.2 - 1.2e-40 137.2 16.3 0.0023 17.8 0.0 11.7 8 4 4 12 12 12 10 Tetratricopeptide repeat CHAT PF12770.2 EAU83838.2 - 8.3e-28 97.3 0.0 1.5e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.1 EAU83838.2 - 3.1e-24 83.0 7.6 0.42 10.9 0.0 11.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EAU83838.2 - 4.4e-18 64.6 27.4 0.066 12.8 0.3 11.8 3 1 9 13 13 13 10 TPR repeat Peptidase_C25 PF01364.13 EAU83838.2 - 0.098 11.6 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 TPR_1 PF00515.23 EAU83838.2 - 0.38 10.4 37.4 26 4.6 0.0 13.5 15 0 0 15 15 15 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU83838.2 - 3.6 7.7 21.5 1.1e+02 3.1 0.0 10.6 13 0 0 13 13 13 0 Tetratricopeptide repeat ATP-synt PF00231.14 EAU83841.2 - 4.9e-70 236.1 4.9 7.2e-70 235.6 3.4 1.2 1 0 0 1 1 1 1 ATP synthase WD40 PF00400.27 EAU83842.1 - 4.9e-36 121.3 4.5 2.7e-09 36.5 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EAU83842.1 - 2.2e-05 24.2 0.1 0.32 10.6 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EAU83842.1 - 0.0026 17.3 0.2 0.93 9.2 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 EAU83842.1 - 0.0051 15.6 0.0 1.4 7.6 0.0 3.0 2 1 0 2 2 2 2 Coatomer WD associated region C1-set PF07654.10 EAU83844.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin C1-set domain Methyltransf_22 PF13383.1 EAU83849.2 - 0.00054 19.5 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L28 PF00830.14 EAU83850.1 - 2.3e-24 84.9 0.5 4.2e-24 84.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Y_phosphatase3C PF13348.1 EAU83850.1 - 0.06 13.4 0.0 0.68 10.0 0.0 2.3 2 1 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Alginate_lyase PF05426.7 EAU83852.2 - 3.1e-39 134.9 3.8 1.8e-38 132.4 0.3 2.4 2 1 1 3 3 3 2 Alginate lyase COesterase PF00135.23 EAU83853.2 - 4.9e-83 279.6 0.0 6.2e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU83853.2 - 2.9e-06 26.9 0.1 2.4e-05 24.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold CBM_1 PF00734.13 EAU83855.1 - 2.4e-10 39.8 8.5 6.5e-10 38.4 5.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DOMON PF03351.12 EAU83855.1 - 2.3e-05 24.3 0.1 7.2e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 DOMON domain NHL PF01436.16 EAU83855.1 - 0.02 14.8 0.2 8.1 6.6 0.0 3.5 4 0 0 4 4 4 0 NHL repeat CBM_1 PF00734.13 EAU83856.1 - 4.3e-11 42.2 7.9 1.1e-10 40.9 5.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DOMON PF03351.12 EAU83856.1 - 0.0024 17.8 0.0 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 DOMON domain NHL PF01436.16 EAU83856.1 - 0.0037 17.1 0.0 0.34 10.9 0.0 3.1 3 0 0 3 3 3 1 NHL repeat Glyco_hydro_61 PF03443.9 EAU83857.1 - 2.6e-59 200.6 0.0 2.9e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 EAU83857.1 - 0.069 13.2 0.1 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase CDC45 PF02724.9 EAU83858.1 - 0.013 13.6 0.3 0.013 13.6 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.8 EAU83858.1 - 0.19 11.7 3.4 1.1 9.3 2.4 2.0 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3729 PF12526.3 EAU83858.1 - 5.5 8.3 13.2 5.7 8.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Trypan_PARP PF05887.6 EAU83858.1 - 6.9 6.4 15.0 0.15 11.9 4.4 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PV-1 PF06637.6 EAU83860.1 - 0.0027 16.3 2.6 0.7 8.3 0.2 2.0 2 0 0 2 2 2 2 PV-1 protein (PLVAP) DUF765 PF05570.6 EAU83860.1 - 0.022 14.7 7.4 1.2 9.2 0.2 2.7 3 0 0 3 3 3 0 Circovirus protein of unknown function (DUF765) DUF2281 PF10047.4 EAU83860.1 - 0.076 13.3 0.0 8.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) Involucrin_N PF10583.4 EAU83860.1 - 0.1 12.8 0.3 11 6.4 0.0 2.7 3 0 0 3 3 3 0 Involucrin of squamous epithelia N-terminus DUF3787 PF12655.2 EAU83860.1 - 0.34 10.6 3.8 9.5 6.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) DUF3564 PF12087.3 EAU83860.1 - 2.1 7.9 6.7 8.3 6.0 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3564) Peroxidase_2 PF01328.12 EAU83861.1 - 4.5e-20 71.5 0.0 5.2e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Metal_resist PF13801.1 EAU83862.1 - 0.00024 21.0 1.6 0.14 12.1 0.0 2.5 3 0 0 3 3 3 2 Heavy-metal resistance Med25 PF11232.3 EAU83862.1 - 0.014 15.1 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Phe_tRNA-synt_N PF02912.13 EAU83862.1 - 0.064 12.9 0.0 8.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Peptidase_M43 PF05572.8 EAU83863.2 - 8.1e-20 70.9 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EAU83863.2 - 6.6e-05 23.0 0.0 9.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAU83863.2 - 0.00056 20.4 0.0 0.0011 19.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU83863.2 - 0.0046 16.9 0.0 0.0085 16.0 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU83863.2 - 0.0057 16.2 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like WT1 PF02165.10 EAU83863.2 - 0.058 12.4 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Wilm's tumour protein Cellulase PF00150.13 EAU83864.2 - 1.3e-11 44.2 0.0 3.2e-06 26.5 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) GWT1 PF06423.7 EAU83865.2 - 1e-33 116.3 0.0 2.9e-33 114.8 0.0 1.8 1 0 0 1 1 1 1 GWT1 EcsB PF05975.7 EAU83865.2 - 0.039 12.4 0.0 0.039 12.4 0.0 2.2 3 0 0 3 3 3 0 Bacterial ABC transporter protein EcsB CBM_1 PF00734.13 EAU83866.2 - 4.3e-10 39.0 6.2 4.3e-10 39.0 4.3 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain GSDH PF07995.6 EAU83866.2 - 0.073 12.1 0.0 5.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Glucose / Sorbosone dehydrogenase GST_N_3 PF13417.1 EAU83867.1 - 2.8e-13 49.8 0.0 4.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU83867.1 - 4.8e-08 32.7 0.3 1.5e-07 31.1 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU83867.1 - 1.9e-05 25.0 0.1 8.7e-05 22.9 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EAU83867.1 - 2.6e-05 24.1 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAU83867.1 - 0.00012 22.2 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU83867.1 - 0.00097 19.0 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank PF00023.25 EAU83868.2 - 1.1e-117 378.3 37.3 1.1e-08 34.4 0.0 17.5 15 2 2 17 17 17 16 Ankyrin repeat Ank_2 PF12796.2 EAU83868.2 - 1.2e-102 336.3 27.8 2.3e-16 59.8 0.3 11.1 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAU83868.2 - 1.7e-75 241.2 11.0 5.2e-05 23.1 0.0 17.5 16 1 1 17 17 17 14 Ankyrin repeat Ank_4 PF13637.1 EAU83868.2 - 1.9e-69 228.9 27.2 2e-09 37.7 0.2 13.7 4 3 10 14 14 14 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU83868.2 - 1.2e-54 181.1 37.0 2.9e-08 33.7 0.4 11.8 7 4 3 11 11 11 11 Ankyrin repeats (many copies) Nitro_FeMo-Co PF02579.12 EAU83868.2 - 0.0023 17.9 0.8 21 5.2 0.0 4.6 3 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor E3_binding PF02817.12 EAU83868.2 - 0.017 14.7 1.1 16 5.2 0.0 4.8 5 0 0 5 5 5 0 e3 binding domain NACHT PF05729.7 EAU83868.2 - 0.061 12.9 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF4302 PF14135.1 EAU83868.2 - 0.41 9.9 0.5 7.1 5.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4302) NMT1_2 PF13379.1 EAU83868.2 - 2.8 7.2 8.7 22 4.3 1.3 4.9 2 2 0 3 3 3 0 NMT1-like family Ank_2 PF12796.2 EAU83870.2 - 1.5e-55 185.4 16.5 6.5e-15 55.2 0.1 6.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAU83870.2 - 2.9e-43 143.5 21.6 2.9e-06 26.7 0.1 9.3 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EAU83870.2 - 3.8e-27 93.6 16.2 2.8e-10 40.1 0.1 7.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU83870.2 - 1e-24 86.3 12.1 2.2e-07 31.1 0.1 7.0 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU83870.2 - 1.2e-24 83.9 2.5 0.057 13.6 0.0 9.3 9 0 0 9 9 9 7 Ankyrin repeat Menin PF05053.8 EAU83872.2 - 0.093 10.8 2.7 0.14 10.3 1.9 1.1 1 0 0 1 1 1 0 Menin Epimerase PF01370.16 EAU83881.2 - 4.2e-17 62.3 0.1 3.2e-16 59.4 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU83881.2 - 5.5e-12 46.0 0.1 1.7e-11 44.5 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAU83881.2 - 1.2e-10 40.5 0.0 1.8e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EAU83881.2 - 1.2e-06 27.9 0.0 2.1e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EAU83881.2 - 3.6e-06 26.9 0.0 5e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EAU83881.2 - 4.3e-05 22.5 0.0 0.00016 20.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EAU83881.2 - 0.0005 19.7 0.0 0.015 14.9 0.0 2.3 1 1 0 1 1 1 1 KR domain DUF365 PF04033.7 EAU83881.2 - 0.44 10.5 2.5 8.8 6.3 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF365) HMG_box PF00505.14 EAU83886.2 - 1.2e-11 44.6 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU83886.2 - 0.001 19.4 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain DUF607 PF04678.8 EAU83887.2 - 1.9e-44 151.7 0.1 3e-44 151.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF607 EMP24_GP25L PF01105.19 EAU83887.2 - 0.048 13.3 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Abhydrolase_6 PF12697.2 EAU83888.2 - 1.8e-08 34.5 0.2 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU83888.2 - 0.013 15.2 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family LRR_4 PF12799.2 EAU83890.2 - 0.0074 15.8 9.6 5.2 6.8 0.0 5.4 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) Hexokinase_2 PF03727.11 EAU83892.2 - 1.9e-81 272.8 0.0 2.6e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EAU83892.2 - 1.9e-67 226.5 0.0 2.6e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 EAU83892.2 - 0.19 10.9 0.0 0.46 9.7 0.0 1.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Ribosomal_L14 PF00238.14 EAU83893.1 - 4.1e-44 149.2 2.1 4.6e-44 149.0 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Fungal_trans PF04082.13 EAU83894.2 - 3.3e-13 49.1 0.1 4.9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU83894.2 - 6.2e-07 29.2 9.4 1.3e-06 28.2 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sin3_corepress PF08295.7 EAU83894.2 - 0.04 13.6 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Sin3 family co-repressor TB2_DP1_HVA22 PF03134.14 EAU83895.2 - 1e-26 92.4 7.8 1.5e-26 91.9 5.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family M PF02370.11 EAU83895.2 - 0.061 13.6 1.1 0.13 12.6 0.7 1.6 1 0 0 1 1 1 0 M protein repeat Ribonuclease PF00545.15 EAU83898.2 - 0.0081 16.2 1.6 0.013 15.5 1.1 1.3 1 0 0 1 1 1 1 ribonuclease EHN PF06441.7 EAU83899.2 - 4.3e-35 120.0 2.5 5.1e-34 116.5 0.0 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EAU83899.2 - 8e-11 42.2 1.7 8e-11 42.2 1.2 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU83899.2 - 1.7e-09 37.6 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU83899.2 - 0.022 14.5 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2157 PF09925.4 EAU83900.2 - 0.029 13.9 0.4 0.075 12.6 0.2 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) Claudin_2 PF13903.1 EAU83900.2 - 0.051 13.2 0.4 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction UPF0104 PF03706.8 EAU83900.2 - 0.11 11.7 3.0 0.59 9.3 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) UcrQ PF02939.11 EAU83901.1 - 6.2e-18 64.3 1.4 7.8e-18 64.0 1.0 1.1 1 0 0 1 1 1 1 UcrQ family CBM_1 PF00734.13 EAU83902.1 - 1.9e-12 46.6 15.8 1.9e-12 46.6 11.0 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU83902.1 - 0.0005 20.0 3.3 0.0011 18.9 2.3 1.6 1 0 0 1 1 1 1 Toxin 7 F-box-like PF12937.2 EAU83905.1 - 0.0088 15.7 0.0 0.035 13.8 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU83906.1 - 0.0088 15.7 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU83906.1 - 0.057 13.1 1.4 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 F-box domain ArfGap PF01412.13 EAU83907.2 - 3.3e-40 136.5 0.6 4.9e-40 135.9 0.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf F-box-like PF12937.2 EAU83908.2 - 5.1e-05 22.9 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like Glyco_transf_90 PF05686.7 EAU83909.1 - 1.2e-16 60.3 1.2 4.3e-08 32.2 0.0 3.9 4 0 0 4 4 4 3 Glycosyl transferase family 90 Epimerase PF01370.16 EAU83910.1 - 1.1e-68 231.2 0.0 1.4e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAU83910.1 - 0.00015 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EAU83910.1 - 0.021 13.7 0.0 0.065 12.1 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.8 EAU83910.1 - 0.067 12.4 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EAU83910.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 EAU83911.2 - 6.1e-52 176.3 0.0 9.3e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAU83911.2 - 4.4e-06 25.7 0.0 9.1e-05 21.4 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EAU83911.2 - 9.8e-06 24.6 0.1 0.0011 17.9 0.1 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EAU83911.2 - 0.007 15.0 0.0 0.01 14.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family EF-hand_2 PF09068.6 EAU83911.2 - 0.069 13.2 0.4 0.12 12.4 0.3 1.6 1 1 0 1 1 1 0 EF hand NAD_binding_4 PF07993.7 EAU83911.2 - 0.12 11.2 0.0 1.7 7.5 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein PAPS_reduct PF01507.14 EAU83912.2 - 1e-19 71.0 0.2 5.2e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ETX_MTX2 PF03318.8 EAU83913.2 - 1.8e-07 30.9 5.1 3.2e-07 30.1 3.6 1.4 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 EAU83913.2 - 3.7e-06 26.1 0.3 5.8e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Aerolysin toxin Mre11_DNA_bind PF04152.9 EAU83914.2 - 3.8e-52 176.6 0.1 3.8e-52 176.6 0.1 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EAU83914.2 - 1e-18 67.4 0.6 1.7e-18 66.7 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU83914.2 - 6.1e-05 22.9 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPT PF03151.11 EAU83915.2 - 1e-10 41.4 11.4 1e-10 41.4 7.9 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 EAU83915.2 - 3.1e-07 30.4 35.7 2.9e-06 27.3 9.3 2.7 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EAU83915.2 - 0.00048 20.2 9.3 0.00048 20.2 6.4 3.3 1 1 3 4 4 4 2 Multidrug resistance efflux transporter p450 PF00067.17 EAU83916.2 - 1.7e-44 152.1 0.0 2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alpha_kinase PF02816.13 EAU83917.2 - 1e-06 28.5 0.9 1.7e-06 27.8 0.6 1.3 1 0 0 1 1 1 1 Alpha-kinase family p450 PF00067.17 EAU83918.2 - 1.5e-15 56.7 0.0 2.2e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Erythro-docking PF09277.6 EAU83918.2 - 0.14 11.8 0.2 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Erythronolide synthase, docking SYF2 PF08231.7 EAU83920.1 - 6.7e-45 152.9 16.4 6.7e-45 152.9 11.4 3.0 3 1 0 3 3 3 2 SYF2 splicing factor TPT PF03151.11 EAU83921.2 - 2.7e-20 72.5 13.3 6.6e-18 64.8 5.8 3.1 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EAU83921.2 - 2.7e-09 36.3 16.9 9.2e-07 28.0 1.1 2.8 3 0 0 3 3 3 2 UAA transporter family EamA PF00892.15 EAU83921.2 - 0.00012 22.0 24.0 0.0068 16.4 2.0 3.6 4 0 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 EAU83921.2 - 0.017 15.3 0.2 0.017 15.3 0.2 3.3 3 0 0 3 3 3 0 Multidrug resistance efflux transporter DUF3808 PF10300.4 EAU83921.2 - 0.24 9.9 0.1 1.1 7.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) TPT PF03151.11 EAU83922.2 - 1.2e-20 73.7 10.7 5.9e-20 71.4 1.0 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EAU83922.2 - 6.5e-10 38.4 12.1 1.7e-06 27.2 0.9 2.8 2 1 1 3 3 3 2 UAA transporter family EamA PF00892.15 EAU83922.2 - 1.2e-05 25.3 26.6 0.00031 20.7 4.3 3.1 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAU83922.2 - 3.1 8.0 20.3 0.23 11.6 1.6 3.3 2 1 1 3 3 3 0 Multidrug resistance efflux transporter SHMT PF00464.14 EAU83923.1 - 5.3e-174 578.2 0.0 6.2e-174 578.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EAU83923.1 - 0.0027 16.8 0.1 0.011 14.9 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase zf-C3HC4_2 PF13923.1 EAU83924.2 - 1.3e-07 31.4 2.1 1.3e-07 31.4 1.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU83924.2 - 8.7e-06 25.2 1.5 8.7e-06 25.2 1.0 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU83924.2 - 6.3e-05 22.7 2.3 6.3e-05 22.7 1.6 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EAU83924.2 - 0.00011 21.9 10.7 0.00011 21.9 7.4 2.9 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EAU83924.2 - 0.00014 21.5 1.7 0.00014 21.5 1.2 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAU83924.2 - 0.0006 19.4 14.7 0.011 15.4 1.2 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU83924.2 - 0.0037 16.9 1.1 0.0037 16.9 0.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Laminin_EGF PF00053.19 EAU83924.2 - 0.0042 16.9 2.0 0.013 15.4 1.4 1.8 1 0 0 1 1 1 1 Laminin EGF-like (Domains III and V) zf-RING_6 PF14835.1 EAU83924.2 - 0.024 14.4 0.2 0.024 14.4 0.2 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EAU83924.2 - 0.59 9.6 6.4 0.34 10.4 1.8 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Arch_ATPase PF01637.13 EAU83925.2 - 2.3e-13 50.4 0.0 1.9e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 EAU83925.2 - 1.1e-06 28.8 0.0 4.5e-06 26.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU83925.2 - 0.00011 22.3 0.0 0.094 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA12 PF10443.4 EAU83925.2 - 0.0015 17.0 0.0 0.039 12.4 0.0 2.4 3 0 0 3 3 3 1 RNA12 protein DUF3246 PF11596.3 EAU83925.2 - 0.003 16.8 0.2 0.0058 15.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) AAA PF00004.24 EAU83925.2 - 0.0094 16.1 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EAU83925.2 - 0.017 14.9 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EAU83925.2 - 0.018 14.9 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Smg4_UPF3 PF03467.10 EAU83926.1 - 7.8e-31 107.4 1.1 1.6e-30 106.3 0.8 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family DUF4121 PF13497.1 EAU83926.1 - 0.13 11.1 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Rifin_STEVOR PF02009.11 EAU83926.1 - 3.3 7.2 10.7 5.9 6.4 7.4 1.3 1 0 0 1 1 1 0 Rifin/stevor family DUF1682 PF07946.9 EAU83927.1 - 0.17 10.7 1.1 0.37 9.6 0.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) COesterase PF00135.23 EAU83928.2 - 8.8e-84 282.1 0.0 1.2e-83 281.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU83928.2 - 9.2e-07 28.6 2.7 5.2e-06 26.1 1.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU83928.2 - 0.0034 16.6 0.7 0.0062 15.7 0.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lectin_C PF00059.16 EAU83928.2 - 0.19 12.4 0.2 0.9 10.2 0.1 2.2 1 1 0 1 1 1 0 Lectin C-type domain Spt5-NGN PF03439.8 EAU83929.2 - 7.1e-22 76.9 0.0 1.4e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 EAU83929.2 - 9.3e-13 47.3 19.1 0.001 18.7 0.1 6.9 7 0 0 7 7 7 3 KOW motif CTD PF12815.2 EAU83929.2 - 4.1e-12 46.5 63.8 5.1e-09 36.5 26.7 3.4 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EAU83929.2 - 1e-10 42.0 11.4 1e-10 42.0 7.9 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal YajC PF02699.10 EAU83929.2 - 0.85 9.3 5.2 1.3 8.7 0.6 3.0 2 1 1 3 3 3 0 Preprotein translocase subunit Epimerase PF01370.16 EAU83930.1 - 4.2e-15 55.8 0.0 4.6e-11 42.6 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU83930.1 - 5e-14 52.7 0.1 3.5e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAU83930.1 - 5e-11 41.8 0.0 7.2e-10 38.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU83930.1 - 3.5e-06 26.1 0.0 1.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EAU83930.1 - 2e-05 24.5 0.0 0.00021 21.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EAU83930.1 - 0.00071 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Thioredoxin_8 PF13905.1 EAU83930.1 - 0.017 15.2 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Polysacc_synt_2 PF02719.10 EAU83930.1 - 0.04 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 EAU83930.1 - 0.055 13.1 0.0 1.1 8.8 0.0 2.3 1 1 0 1 1 1 0 KR domain RRM_1 PF00076.17 EAU83930.1 - 0.13 11.9 0.1 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DJ-1_PfpI PF01965.19 EAU83931.1 - 1.1e-22 80.0 0.0 1.4e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EAU83931.1 - 1.6e-12 47.0 0.0 2e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EAU83931.1 - 0.061 12.9 0.1 0.096 12.2 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4255 PF14065.1 EAU83932.2 - 0.0036 16.7 0.2 0.0051 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4255) DUF543 PF04418.7 EAU83933.1 - 2e-27 94.9 0.2 2.3e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-C3HC4_2 PF13923.1 EAU83936.2 - 5.2e-11 42.3 19.5 4.4e-06 26.6 1.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU83936.2 - 1.1e-10 41.0 16.8 2.7e-07 30.1 5.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EAU83936.2 - 5.7e-10 38.8 13.3 5.4e-07 29.0 0.8 2.7 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.1 EAU83936.2 - 7e-07 28.9 16.4 0.0018 18.0 5.8 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EAU83936.2 - 1e-06 28.3 21.8 3.2e-06 26.7 7.0 2.6 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU83936.2 - 1.7e-05 24.3 20.2 0.011 15.4 7.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU83936.2 - 0.0007 19.4 15.5 0.02 14.7 0.9 2.6 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING Atg14 PF10186.4 EAU83936.2 - 0.0065 15.4 0.9 0.0065 15.4 0.6 1.6 2 0 0 2 2 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-RING_UBOX PF13445.1 EAU83936.2 - 0.11 12.2 12.7 0.81 9.4 3.8 2.9 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING_6 PF14835.1 EAU83936.2 - 0.29 10.9 9.1 0.15 11.8 0.9 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.16 EAU83936.2 - 0.39 10.6 12.0 0.29 11.0 2.4 2.9 2 1 0 2 2 2 0 FYVE zinc finger zf-rbx1 PF12678.2 EAU83936.2 - 0.96 9.6 9.8 0.29 11.2 2.9 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger DivIC PF04977.10 EAU83936.2 - 1.1 8.8 4.5 2.6 7.5 3.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DZR PF12773.2 EAU83936.2 - 1.4 8.7 14.9 0.94 9.3 5.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon Borrelia_P83 PF05262.6 EAU83936.2 - 3.5 5.7 6.3 5.4 5.1 4.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Siva PF05458.7 EAU83936.2 - 9.1 5.8 9.9 2.3 7.7 2.0 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) DUF3833 PF12915.2 EAU83937.2 - 0.00063 19.0 0.1 0.0014 17.8 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3833) CHB_HEX_C PF03174.8 EAU83937.2 - 0.035 13.9 2.4 0.085 12.7 1.7 1.7 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain SnoaL_3 PF13474.1 EAU83937.2 - 0.039 13.9 0.2 0.052 13.5 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.2 EAU83937.2 - 0.084 13.2 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain Med18 PF09637.5 EAU83937.2 - 0.13 11.7 0.1 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Med18 protein WD40 PF00400.27 EAU83940.1 - 1.8e-30 103.6 15.3 4.3e-10 39.0 0.2 7.8 8 1 0 8 8 8 7 WD domain, G-beta repeat Sof1 PF04158.9 EAU83940.1 - 7.4e-25 86.7 5.0 7.4e-25 86.7 3.5 2.0 2 0 0 2 2 2 1 Sof1-like domain RGS PF00615.14 EAU83942.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Lactamase_B_2 PF12706.2 EAU83943.2 - 8.1e-09 35.2 0.1 1.6e-08 34.3 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAU83943.2 - 0.0051 16.4 1.9 0.017 14.7 1.4 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4298 PF14131.1 EAU83944.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) HAUS6_N PF14661.1 EAU83944.1 - 0.065 12.5 0.2 0.096 12.0 0.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus BLOC1_2 PF10046.4 EAU83944.1 - 0.088 12.9 1.1 0.17 12.0 0.8 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps26 PF03643.10 EAU83945.1 - 2.2e-123 410.4 5.1 1.4e-122 407.7 3.6 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EAU83945.1 - 0.0028 17.4 0.1 0.049 13.4 0.1 2.6 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EAU83945.1 - 0.015 15.3 1.4 0.16 12.1 0.2 2.8 2 1 1 3 3 3 0 Arrestin (or S-antigen), C-terminal domain AAA_5 PF07728.9 EAU83946.2 - 7.4e-70 233.0 0.0 2.5e-29 101.7 0.0 3.7 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) vWA-TerF-like PF10138.4 EAU83946.2 - 0.11 12.2 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 vWA found in TerF C terminus AAA PF00004.24 EAU83946.2 - 0.17 12.1 0.0 0.91 9.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3464 PF11947.3 EAU83947.1 - 0.0074 15.7 0.8 0.0074 15.7 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3464) UPF0104 PF03706.8 EAU83947.1 - 0.03 13.5 17.5 0.043 13.1 12.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF1469 PF07332.6 EAU83947.1 - 3.5 7.3 15.0 1.3 8.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) NAD_binding_6 PF08030.7 EAU83948.1 - 3.3e-37 127.7 0.0 5.3e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAU83948.1 - 3e-22 78.4 0.0 6e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EAU83948.1 - 6.9e-15 55.2 9.5 6.9e-15 55.2 6.6 2.7 2 1 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EAU83948.1 - 0.00036 20.5 0.0 0.0012 18.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EAU83948.1 - 0.011 16.3 0.1 0.21 12.1 0.1 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain PNP_UDP_1 PF01048.15 EAU83949.1 - 5.4e-37 127.0 0.0 6.7e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Sds3 PF08598.6 EAU83950.2 - 2.2e-19 69.8 0.0 2.2e-19 69.8 0.0 4.3 3 2 0 3 3 3 1 Sds3-like Fungal_trans PF04082.13 EAU83952.2 - 8.6e-38 129.6 0.0 1.5e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU83952.2 - 0.0026 17.6 12.9 0.0049 16.7 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2013 PF09431.5 EAU83953.2 - 2.4e-35 121.3 2.2 5.2e-35 120.2 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Merozoite_SPAM PF07133.6 EAU83953.2 - 0.26 11.1 0.2 26 4.6 0.1 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Amidase PF01425.16 EAU83954.1 - 2.4e-103 346.3 0.0 2.9e-103 346.1 0.0 1.0 1 0 0 1 1 1 1 Amidase CLN6 PF15156.1 EAU83954.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 6 MFS_1 PF07690.11 EAU83958.2 - 1.9e-41 141.9 25.2 2.6e-41 141.5 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAU83958.2 - 0.002 17.8 0.3 0.0058 16.3 0.2 1.8 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.11 EAU83959.1 - 5.7e-38 130.5 38.0 7.8e-38 130.0 26.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M20 PF01546.23 EAU83960.1 - 6.7e-10 38.7 0.1 1.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAU83960.1 - 7.9e-07 28.8 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain AAA_12 PF13087.1 EAU83962.2 - 3.6e-57 192.9 0.0 6.1e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU83962.2 - 6.5e-57 192.8 0.3 1.4e-56 191.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EAU83962.2 - 7.2e-09 35.5 0.1 0.0083 15.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EAU83962.2 - 9.9e-08 31.6 0.2 5e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAU83962.2 - 3.9e-07 29.8 0.1 0.038 13.5 0.4 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.1 EAU83962.2 - 0.00041 20.4 0.1 0.077 13.1 0.0 2.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain ResIII PF04851.10 EAU83962.2 - 0.0032 17.3 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EAU83962.2 - 0.0054 15.7 0.3 0.21 10.5 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAU83962.2 - 0.06 13.4 0.1 4 7.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain UvrD_C PF13361.1 EAU83962.2 - 0.061 12.7 0.3 0.45 9.9 0.1 2.3 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EAU83962.2 - 0.1 11.8 0.0 1.8 7.7 0.0 2.3 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain CDC45 PF02724.9 EAU83962.2 - 0.69 7.8 8.2 1.1 7.2 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein ApbA PF02558.11 EAU83963.1 - 2.3e-22 79.0 0.1 4.2e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EAU83963.1 - 2.8e-18 66.1 0.0 1.9e-16 60.2 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.1 EAU83963.1 - 0.0099 16.1 0.1 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Piwi PF02171.12 EAU83964.2 - 5.9e-81 271.7 0.0 9e-81 271.1 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EAU83964.2 - 2.9e-18 65.4 0.0 5.6e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EAU83964.2 - 8.1e-17 60.3 0.1 1.8e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) SBDS PF01172.13 EAU83968.1 - 3.6e-18 65.1 0.3 4e-18 64.9 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein EHN PF06441.7 EAU83969.2 - 1e-36 125.2 0.6 9.3e-35 118.9 0.0 2.4 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EAU83969.2 - 2.9e-10 40.4 1.7 3.3e-10 40.2 0.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU83969.2 - 8.1e-09 35.3 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2085 PF09858.4 EAU83970.2 - 0.029 14.4 0.1 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) zf-DHHC PF01529.15 EAU83972.2 - 7.6 5.9 12.6 0.93 8.8 5.7 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase EST1_DNA_bind PF10373.4 EAU83974.2 - 2.3e-33 115.6 0.0 5.4e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EAU83974.2 - 2.5e-14 53.3 0.3 8.8e-14 51.6 0.0 2.2 3 0 0 3 3 3 1 Telomerase activating protein Est1 DEAD PF00270.24 EAU83976.2 - 2.1e-44 150.9 0.0 4.8e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EAU83976.2 - 8.9e-26 89.2 0.0 1.7e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EAU83976.2 - 6e-20 70.8 0.0 1.4e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU83976.2 - 0.0064 16.3 2.2 0.044 13.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit EBV-NA3 PF05009.7 EAU83976.2 - 0.51 9.5 2.3 0.86 8.8 1.6 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CLN3 PF02487.12 EAU83977.1 - 4.4e-62 210.1 3.3 2.1e-59 201.3 2.3 2.4 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 EAU83977.1 - 0.19 10.4 22.2 0.65 8.6 15.4 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily Vac_Fusion PF02346.11 EAU83979.2 - 0.03 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein Mgr1 PF08602.5 EAU83979.2 - 0.034 13.1 0.0 0.044 12.8 0.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Tropomyosin_1 PF12718.2 EAU83980.2 - 1.7e-06 27.9 1.9 0.00064 19.5 0.4 2.9 1 1 2 3 3 3 2 Tropomyosin like Tropomyosin PF00261.15 EAU83980.2 - 0.0017 17.5 6.9 0.0078 15.3 4.9 2.2 1 1 0 1 1 1 1 Tropomyosin TBPIP PF07106.8 EAU83980.2 - 0.02 14.4 0.5 0.75 9.3 0.1 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 EAU83980.2 - 0.054 13.2 0.2 0.48 10.1 0.0 2.4 2 1 1 3 3 3 0 Laminin Domain II GAS PF13851.1 EAU83980.2 - 0.47 9.6 1.7 1.3 8.1 0.2 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nop14 PF04147.7 EAU83980.2 - 0.58 8.0 15.7 0.98 7.2 10.9 1.3 1 0 0 1 1 1 0 Nop14-like family IncA PF04156.9 EAU83980.2 - 0.88 9.1 3.0 2.2 7.8 0.2 2.2 2 0 0 2 2 2 0 IncA protein CDC45 PF02724.9 EAU83980.2 - 1.5 6.7 10.1 2.2 6.2 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 EAU83980.2 - 2 8.0 13.5 5.5 6.6 9.4 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein COPI_C PF06957.6 EAU83980.2 - 2.2 6.7 10.0 4.1 5.8 6.9 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus HMG_box_2 PF09011.5 EAU83981.1 - 0.027 14.8 0.1 0.08 13.3 0.1 1.8 1 0 0 1 1 1 0 HMG-box domain BNIP2 PF12496.3 EAU83981.1 - 0.028 14.5 0.6 0.063 13.4 0.4 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Tet_JBP PF12851.2 EAU83986.2 - 7.5e-14 51.3 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HrpB7 PF09486.5 EAU83987.2 - 0.034 14.0 1.0 0.062 13.2 0.2 1.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CASP_C PF08172.7 EAU83987.2 - 0.049 12.6 0.1 0.077 12.0 0.1 1.3 1 0 0 1 1 1 0 CASP C terminal IncA PF04156.9 EAU83987.2 - 0.065 12.8 0.2 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 IncA protein DUF4200 PF13863.1 EAU83987.2 - 0.091 12.7 0.3 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 EAU83987.2 - 0.11 12.2 1.1 0.21 11.3 0.0 2.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Tet_JBP PF12851.2 EAU83988.1 - 3.7e-20 71.9 0.0 8.5e-20 70.7 0.0 1.5 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.2 EAU83989.2 - 1.7e-08 33.9 0.0 3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HMG_box_2 PF09011.5 EAU83991.2 - 3.6e-05 24.0 0.2 3.6e-05 24.0 0.1 2.7 2 0 0 2 2 2 1 HMG-box domain Daxx PF03344.10 EAU83991.2 - 0.0012 17.4 27.7 0.0012 17.4 19.2 2.4 2 0 0 2 2 2 1 Daxx Family CNTF PF01110.12 EAU83991.2 - 0.045 13.0 0.1 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Ciliary neurotrophic factor Zn_clus PF00172.13 EAU83992.1 - 0.055 13.3 12.0 0.086 12.7 8.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CM_2 PF01817.16 EAU83997.2 - 3.1e-17 62.4 0.2 4.2e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 Chorismate mutase type II Dor1 PF04124.7 EAU83997.2 - 0.016 13.6 0.1 0.019 13.4 0.1 1.0 1 0 0 1 1 1 0 Dor1-like family Phage_min_cap2 PF06152.6 EAU83997.2 - 0.082 11.8 0.2 0.11 11.4 0.2 1.0 1 0 0 1 1 1 0 Phage minor capsid protein 2 G-alpha PF00503.15 EAU83998.2 - 4.9e-114 381.0 0.0 6.1e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU83998.2 - 8e-08 31.7 0.5 1.5e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MIP PF00230.15 EAU83999.1 - 2.9e-53 180.6 11.7 3.8e-53 180.2 8.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.15 EAU83999.1 - 0.015 15.3 11.0 0.068 13.2 2.9 2.6 2 0 0 2 2 2 0 EamA-like transporter family Complex1_LYR_1 PF13232.1 EAU84000.1 - 6.9e-17 61.4 0.4 9.4e-17 60.9 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EAU84000.1 - 5.1e-15 54.9 0.2 6.4e-15 54.6 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HIG_1_N PF04588.8 EAU84001.1 - 2.4e-25 88.0 0.6 4e-25 87.3 0.4 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Sds3 PF08598.6 EAU84001.1 - 0.0028 17.2 0.8 0.0037 16.8 0.6 1.2 1 0 0 1 1 1 1 Sds3-like MSC PF09402.5 EAU84001.1 - 0.01 14.5 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain APC_CDC26 PF10471.4 EAU84001.1 - 0.071 13.8 0.8 0.13 12.9 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Urm1 PF09138.6 EAU84002.1 - 8e-34 115.6 0.1 1.8e-32 111.3 0.1 2.0 1 1 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EAU84002.1 - 5.6e-06 26.7 0.0 8.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ThiS family Ribosomal_S30 PF04758.9 EAU84003.2 - 1.1e-28 98.7 5.4 1.9e-28 97.9 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S30 zf-C2H2 PF00096.21 EAU84003.2 - 1.8e-05 24.8 7.0 0.016 15.5 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EAU84003.2 - 0.00074 19.6 2.4 0.0063 16.6 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAU84003.2 - 0.0036 17.4 3.4 0.04 14.0 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EAU84003.2 - 0.0044 17.2 4.1 0.29 11.5 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU84003.2 - 0.014 15.6 4.7 0.38 11.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain SR-25 PF10500.4 EAU84003.2 - 0.017 14.5 4.7 0.025 14.0 3.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-C2H2_2 PF12756.2 EAU84003.2 - 0.025 14.6 1.9 0.13 12.3 1.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) 2-Hacid_dh_C PF02826.14 EAU84004.1 - 1.6e-54 183.7 0.0 2.4e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAU84004.1 - 2.4e-31 107.9 0.0 2.7e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EAU84004.1 - 2.1e-05 24.4 0.0 5.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EAU84004.1 - 0.018 15.4 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MCM PF00493.18 EAU84005.2 - 1.5e-135 451.3 0.0 1.9e-135 450.9 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAU84005.2 - 6.7e-20 71.7 0.1 4.4e-19 69.1 0.0 2.4 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EAU84005.2 - 2.8e-08 33.5 0.0 7.8e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EAU84005.2 - 1.9e-07 30.4 0.0 5.1e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAU84005.2 - 0.00028 20.4 0.0 0.0044 16.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EAU84005.2 - 0.00089 18.7 0.1 1.2 8.6 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain DUF3256 PF11644.3 EAU84005.2 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3256) Con-6 PF10346.4 EAU84006.1 - 9.2e-34 114.5 2.8 1.5e-17 62.7 0.2 2.2 2 0 0 2 2 2 2 Conidiation protein 6 Abhydrolase_3 PF07859.8 EAU84007.2 - 2.2e-26 92.7 0.0 4.8e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU84007.2 - 4.5e-10 38.7 0.0 7.5e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAU84007.2 - 0.0034 17.1 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Con-6 PF10346.4 EAU84008.1 - 2.6e-24 84.3 3.0 1.5e-16 59.4 0.5 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 EAU84008.1 - 0.0032 16.9 0.4 0.4 10.1 0.0 2.2 2 1 0 2 2 2 2 SpoIIIAH-like protein Pilus_CpaD PF09476.5 EAU84008.1 - 0.041 13.3 0.2 0.1 12.0 0.0 1.6 1 1 1 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Glyco_hydro_16 PF00722.16 EAU84009.2 - 9.3e-08 31.5 0.0 5.3e-07 29.0 0.0 2.0 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Con-6 PF10346.4 EAU84010.1 - 2.2e-06 26.9 0.9 0.00027 20.2 0.2 2.4 2 0 0 2 2 2 2 Conidiation protein 6 Con-6 PF10346.4 EAU84012.1 - 9.6e-31 104.9 6.1 5.1e-17 61.0 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 PASTA PF03793.14 EAU84012.1 - 0.00017 21.2 0.7 0.00052 19.6 0.1 1.9 2 0 0 2 2 2 1 PASTA domain SpoIIIAH PF12685.2 EAU84012.1 - 0.0061 16.0 3.3 0.17 11.3 0.3 2.2 1 1 1 2 2 2 2 SpoIIIAH-like protein YhzD PF14120.1 EAU84012.1 - 0.024 14.5 0.5 3.4 7.6 0.0 2.1 2 0 0 2 2 2 0 YhzD-like protein Toxin_52 PF15605.1 EAU84012.1 - 0.079 12.8 0.5 5.2 7.0 0.0 2.1 1 1 1 2 2 2 0 Putative toxin 52 Coleoptericin PF06286.6 EAU84013.2 - 0.043 13.7 0.3 0.69 9.8 0.2 2.2 1 1 0 1 1 1 0 Coleoptericin BTB PF00651.26 EAU84013.2 - 0.096 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain p450 PF00067.17 EAU84014.2 - 5.6e-67 226.2 0.0 6.7e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU84016.2 - 2.9e-55 187.6 0.0 3.3e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU84017.2 - 1.4e-46 158.9 0.0 2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.16 EAU84018.1 - 4.6e-47 160.0 0.1 7e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EAU84018.1 - 6.6e-10 38.4 3.9 0.00029 20.4 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAU84018.1 - 4.7e-06 26.1 11.2 0.0015 18.3 1.4 3.5 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU84018.1 - 3.9e-05 23.4 0.7 0.066 13.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU84018.1 - 0.00029 20.3 10.7 0.00032 20.1 0.8 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU84018.1 - 0.0092 15.6 1.3 0.0092 15.6 0.9 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAU84018.1 - 0.021 14.7 0.3 11 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAU84018.1 - 0.09 13.4 14.7 0.63 10.7 2.6 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAU84018.1 - 0.098 13.3 5.4 0.41 11.4 1.6 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.8 EAU84018.1 - 0.66 9.5 3.1 0.75 9.3 1.3 1.7 2 0 0 2 2 2 0 HemY protein N-terminus TPR_6 PF13174.1 EAU84018.1 - 0.96 10.0 6.9 1.9 9.0 0.8 3.6 3 1 0 4 4 3 0 Tetratricopeptide repeat RhoGAP PF00620.22 EAU84019.2 - 6.5e-06 25.8 0.0 2.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain Motile_Sperm PF00635.21 EAU84019.2 - 0.023 14.3 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain PapD-like PF14874.1 EAU84019.2 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like Exo_endo_phos PF03372.18 EAU84020.2 - 1.5e-06 28.3 0.0 3.9e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.23 EAU84021.1 - 1.7e-11 44.6 0.0 1.2e-10 41.9 0.0 2.3 2 1 0 2 2 2 1 SET domain Cys_rich_CWC PF14375.1 EAU84021.1 - 0.068 13.1 0.7 0.14 12.1 0.5 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC Gemini_AC4_5 PF04807.7 EAU84021.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region HABP4_PAI-RBP1 PF04774.10 EAU84022.1 - 0.0011 19.4 1.7 0.0034 17.8 1.2 1.8 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family DUF3941 PF13081.1 EAU84022.1 - 0.7 9.9 2.6 1.3 9.0 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) SET PF00856.23 EAU84025.1 - 4.3e-10 40.1 0.0 4.2e-09 36.9 0.0 2.4 1 1 0 1 1 1 1 SET domain Transpos_assoc PF13963.1 EAU84025.1 - 0.092 12.7 1.2 0.22 11.5 0.8 1.7 1 0 0 1 1 1 0 Transposase-associated domain Iso_dh PF00180.15 EAU84027.1 - 2.7e-74 250.1 0.0 3.3e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-CCHC PF00098.18 EAU84029.2 - 0.0028 17.4 1.8 0.0058 16.5 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 EAU84029.2 - 0.0095 15.5 1.4 0.026 14.1 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EAU84029.2 - 0.086 12.5 1.2 0.17 11.5 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_11 PF00457.12 EAU84034.1 - 1.4e-57 194.0 14.2 1.6e-57 193.8 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 LEAP-2 PF07359.6 EAU84034.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Dus PF01207.12 EAU84036.1 - 3.8e-53 180.3 0.0 6.5e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EAU84036.1 - 6.9e-05 22.4 6.2 0.057 13.1 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) p450 PF00067.17 EAU84038.1 - 2.2e-71 240.7 0.0 2.1e-62 211.1 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 TPR_19 PF14559.1 EAU84041.1 - 2.3e-09 37.4 7.0 0.017 15.4 0.2 4.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAU84041.1 - 1.6e-08 34.9 0.9 8.9e-05 23.0 0.0 4.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU84041.1 - 5.2e-08 32.4 0.3 3e-06 26.7 0.0 2.5 1 1 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EAU84041.1 - 1.2e-07 31.7 6.7 0.00094 19.6 0.1 4.5 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU84041.1 - 5.3e-07 29.3 0.3 0.22 11.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU84041.1 - 9e-06 25.2 2.5 0.0038 17.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU84041.1 - 0.0022 17.6 0.1 0.23 11.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU84041.1 - 0.0031 17.0 0.1 0.025 14.1 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU84041.1 - 0.0084 16.0 1.6 0.12 12.3 0.0 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EAU84041.1 - 0.013 15.6 0.4 0.058 13.5 0.1 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EAU84041.1 - 0.036 13.9 1.1 0.28 11.0 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EAU84041.1 - 0.05 12.6 2.3 0.056 12.4 0.4 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Imm43 PF15602.1 EAU84041.1 - 0.057 13.3 0.0 0.099 12.6 0.0 1.5 1 1 0 1 1 1 0 Immunity protein 43 TipAS PF07739.8 EAU84041.1 - 0.079 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain TPR_20 PF14561.1 EAU84041.1 - 0.12 12.5 0.7 3.5 7.8 0.0 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU84041.1 - 2 9.0 4.0 15 6.3 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat DHH PF01368.15 EAU84042.2 - 1.6e-12 47.2 0.0 1.6e-12 47.2 0.0 2.3 2 1 0 2 2 2 1 DHH family Macoilin PF09726.4 EAU84043.2 - 2.4 6.3 7.1 3.1 5.9 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein SF-assemblin PF06705.6 EAU84044.2 - 0.029 13.5 0.1 0.029 13.5 0.1 1.6 2 0 0 2 2 2 0 SF-assemblin/beta giardin Reo_sigmaC PF04582.7 EAU84044.2 - 0.044 12.9 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Glucosaminidase PF01832.15 EAU84044.2 - 0.064 13.3 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase CorA PF01544.13 EAU84044.2 - 0.18 10.8 2.1 8.1 5.3 0.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein WD40 PF00400.27 EAU84045.2 - 5.5e-09 35.5 1.2 0.17 11.8 0.0 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat DUF3394 PF11874.3 EAU84045.2 - 0.017 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Nup160 PF11715.3 EAU84045.2 - 0.034 12.2 0.1 0.083 11.0 0.0 1.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 IpgD PF05925.7 EAU84045.2 - 0.11 10.6 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD Aldedh PF00171.17 EAU84047.2 - 8.5e-128 426.5 0.0 9.9e-128 426.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.27 EAU84048.2 - 6.3e-09 35.3 10.0 0.013 15.3 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat BUD22 PF09073.5 EAU84048.2 - 2.4 7.1 21.2 4.3 6.3 14.7 1.3 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.20 EAU84049.1 - 1.5e-24 86.5 0.0 2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84049.1 - 3.1e-09 36.3 0.0 6.2e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAU84049.1 - 0.00072 18.6 0.1 0.0012 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU84049.1 - 0.0062 16.3 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Thr_synth_N PF14821.1 EAU84052.2 - 1.3e-27 95.6 0.0 2.8e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EAU84052.2 - 3.9e-19 69.0 0.1 4.5e-18 65.5 0.1 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4440 PF14534.1 EAU84053.1 - 0.00075 19.6 0.0 0.00085 19.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EAU84053.1 - 0.0014 19.0 0.0 0.0019 18.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF2683 PF10884.3 EAU84053.1 - 0.035 14.0 0.0 0.067 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2683) SnoaL_3 PF13474.1 EAU84053.1 - 0.081 12.9 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain SnoaL PF07366.7 EAU84053.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase ADIP PF11559.3 EAU84054.2 - 0.051 13.4 4.7 0.055 13.3 1.9 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4559 PF15112.1 EAU84054.2 - 0.15 11.1 0.3 0.22 10.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) PP2C PF00481.16 EAU84055.2 - 1.4e-29 103.2 0.0 2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EAU84055.2 - 1.3e-10 41.3 0.1 3.3e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EAU84055.2 - 2.7e-07 30.2 0.0 3.9e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C STAG PF08514.6 EAU84056.2 - 1.1e-28 99.3 2.8 2.1e-28 98.4 0.1 2.8 2 1 1 3 3 3 1 STAG domain HEAT_2 PF13646.1 EAU84056.2 - 4.4e-10 39.6 0.0 3.3e-05 24.0 0.0 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 EAU84056.2 - 0.00012 21.8 0.3 4.1 7.7 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat CDC45 PF02724.9 EAU84056.2 - 1.5 6.8 14.3 23 2.8 8.8 2.7 2 0 0 2 2 2 0 CDC45-like protein UPF0233 PF06781.7 EAU84059.2 - 0.015 14.9 1.6 0.035 13.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF2417 PF10329.4 EAU84059.2 - 0.018 14.4 0.4 0.03 13.7 0.3 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF3481 PF11980.3 EAU84059.2 - 0.24 11.2 1.3 3 7.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3481) FxsA PF04186.8 EAU84059.2 - 0.37 10.4 4.6 0.58 9.7 0.1 2.7 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein WD40 PF00400.27 EAU84060.2 - 9.4e-54 177.4 10.9 7.9e-10 38.2 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EAU84060.2 - 3.6e-06 25.4 6.9 0.055 11.5 0.0 4.6 3 1 1 4 4 4 3 Nucleoporin Nup120/160 F-box-like PF12937.2 EAU84060.2 - 0.0044 16.7 6.7 0.039 13.6 4.6 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EAU84060.2 - 0.022 14.4 0.1 0.022 14.4 0.1 1.9 2 0 0 2 2 2 0 F-box domain PQQ_2 PF13360.1 EAU84060.2 - 0.023 14.1 0.0 1.6 8.1 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain DUF4094 PF13334.1 EAU84061.2 - 0.027 14.8 1.4 0.11 12.9 1.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) CorA PF01544.13 EAU84062.2 - 5.1e-12 45.4 2.6 1.3e-11 44.1 1.8 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.13 EAU84063.2 - 5.4e-10 38.7 8.1 1.4e-09 37.4 5.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein ArsB PF02040.10 EAU84064.1 - 1.8e-14 53.5 26.2 3.8e-13 49.1 7.5 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.11 EAU84064.1 - 2.3e-06 26.4 30.2 5.3e-06 25.2 11.1 2.3 2 0 0 2 2 2 2 Citrate transporter tRNA-synt_2b PF00587.20 EAU84065.1 - 4.5e-35 120.7 1.2 2.8e-34 118.1 0.1 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EAU84065.1 - 9.7e-20 70.5 8.2 9.7e-20 70.5 5.7 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 EAU84065.1 - 0.076 12.8 2.2 0.16 11.8 1.5 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Gly_transf_sug PF04488.10 EAU84066.2 - 3.4e-05 24.1 0.0 8.3e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EAU84066.2 - 0.041 13.0 0.2 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF4569 PF15133.1 EAU84067.1 - 0.51 9.6 5.2 0.3 10.4 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) Ribonuc_2-5A PF06479.7 EAU84069.1 - 1.7e-44 150.7 0.1 2.9e-44 150.0 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EAU84069.1 - 3.9e-40 137.6 0.0 5.9e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84069.1 - 4.1e-19 68.6 0.0 3.3e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.16 EAU84069.1 - 0.0011 18.4 0.0 0.0088 15.5 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat PQQ_2 PF13360.1 EAU84069.1 - 0.0014 18.1 0.0 0.0044 16.5 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 EAU84069.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MoCF_biosynth PF00994.19 EAU84070.1 - 1.3e-35 121.9 0.0 3e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain Flg_hook PF02120.11 EAU84070.1 - 0.051 13.2 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK FAD_syn PF06574.7 EAU84070.1 - 0.11 12.1 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 FAD synthetase UPF0139 PF03669.8 EAU84071.1 - 0.0043 16.5 0.0 0.008 15.6 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) Inhibitor_I9 PF05922.11 EAU84072.1 - 2e-09 37.8 0.0 2.4e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 BetaGal_dom2 PF10435.4 EAU84072.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 DUF1129 PF06570.6 EAU84073.2 - 0.0034 16.7 1.3 0.004 16.4 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF4282 PF14110.1 EAU84073.2 - 0.081 13.1 0.7 0.081 13.1 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4282) DUF805 PF05656.9 EAU84073.2 - 0.49 10.2 4.6 0.86 9.4 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Peptidase_S24 PF00717.18 EAU84074.1 - 7.9e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like RNase_H_2 PF13482.1 EAU84074.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 RNase_H superfamily GPI-anchored PF10342.4 EAU84075.2 - 5.1e-09 36.5 0.1 9.4e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3246 PF11596.3 EAU84075.2 - 0.016 14.4 3.2 0.016 14.4 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Zn_clus PF00172.13 EAU84076.1 - 5.9e-05 22.8 9.7 0.0001 22.1 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAU84076.1 - 0.0012 17.8 0.0 0.0024 16.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GTP1_OBG PF01018.17 EAU84077.1 - 7.2e-37 126.4 0.6 6e-25 87.7 0.0 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EAU84077.1 - 1.7e-18 66.6 0.0 5.4e-18 65.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU84077.1 - 2e-06 27.1 0.0 7.6e-06 25.2 0.0 2.0 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EAU84077.1 - 0.00013 21.4 0.4 0.0021 17.5 0.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EAU84077.1 - 0.00029 20.1 0.3 0.4 9.9 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.14 EAU84077.1 - 0.00044 19.7 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EAU84077.1 - 0.00047 20.6 0.0 0.035 14.5 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EAU84077.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 1 1 0 1 1 1 1 Dynamin family ArgK PF03308.11 EAU84077.1 - 0.0015 17.3 1.6 0.43 9.3 0.1 2.3 2 0 0 2 2 2 2 ArgK protein Gtr1_RagA PF04670.7 EAU84077.1 - 0.0053 15.9 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.22 EAU84077.1 - 0.013 15.8 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter DUF3602 PF12223.3 EAU84077.1 - 0.055 13.8 0.9 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) AAA_17 PF13207.1 EAU84077.1 - 0.2 12.4 1.3 0.75 10.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EAU84077.1 - 0.47 10.7 0.0 0.47 10.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain HLH PF00010.21 EAU84078.2 - 1.1e-11 44.2 0.2 3.1e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2423 PF10338.4 EAU84078.2 - 6 6.9 7.3 12 6.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) WD40 PF00400.27 EAU84079.2 - 5.5e-16 57.7 11.2 2.1e-06 27.4 0.1 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat HAND PF09110.6 EAU84079.2 - 0.16 12.3 4.8 0.52 10.7 3.3 1.8 1 0 0 1 1 1 0 HAND Con-6 PF10346.4 EAU84080.1 - 3.2e-48 160.8 11.1 2.5e-17 62.0 0.2 3.1 3 0 0 3 3 3 3 Conidiation protein 6 DEC-1_C PF04626.8 EAU84080.1 - 0.00045 20.4 0.7 0.0069 16.5 0.3 2.4 1 1 1 2 2 2 1 Dec-1 protein, C terminal region SpoIIIAH PF12685.2 EAU84080.1 - 0.0011 18.4 4.7 0.11 11.9 0.0 3.0 2 1 0 3 3 3 2 SpoIIIAH-like protein Toxin_52 PF15605.1 EAU84080.1 - 0.033 14.0 1.6 2.5 8.0 0.0 2.9 2 1 0 3 3 3 0 Putative toxin 52 B PF02216.11 EAU84080.1 - 0.052 13.3 0.2 8.9 6.1 0.0 2.6 2 0 0 2 2 2 0 B domain YhzD PF14120.1 EAU84080.1 - 0.22 11.4 2.3 27 4.7 0.0 3.0 3 0 0 3 3 3 0 YhzD-like protein FIVAR PF07554.8 EAU84080.1 - 0.26 11.5 3.5 3.8 7.8 0.0 3.4 3 1 0 3 3 3 0 Uncharacterised Sugar-binding Domain AAA_12 PF13087.1 EAU84082.2 - 5.2e-32 110.8 0.1 1.5e-31 109.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU84082.2 - 8e-20 71.4 0.2 2.8e-10 40.1 0.0 3.3 3 1 1 4 4 3 2 AAA domain AAA_30 PF13604.1 EAU84082.2 - 2.1e-18 66.6 0.0 3e-17 62.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU84082.2 - 7.3e-10 38.4 0.0 6.5e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EAU84082.2 - 2.3e-05 24.0 0.1 0.47 9.9 0.0 3.4 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EAU84082.2 - 0.00038 20.4 0.0 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAU84082.2 - 0.0004 21.2 0.1 0.002 18.9 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EAU84082.2 - 0.00075 19.6 0.0 0.013 15.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 EAU84082.2 - 0.00094 19.3 0.0 0.0029 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EAU84082.2 - 0.0015 17.6 0.0 0.81 8.6 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EAU84082.2 - 0.0023 16.9 0.0 0.005 15.8 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.10 EAU84082.2 - 0.0024 17.7 0.0 0.0064 16.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EAU84082.2 - 0.0024 16.8 0.0 0.0048 15.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Y_phosphatase PF00102.22 EAU84082.2 - 0.0032 16.8 0.0 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase AAA_18 PF13238.1 EAU84082.2 - 0.0042 17.3 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.1 EAU84082.2 - 0.0069 16.3 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 EAU84082.2 - 0.0072 15.9 0.8 0.12 11.9 0.0 3.1 3 1 0 3 3 3 1 Helicase AAA_33 PF13671.1 EAU84082.2 - 0.0091 15.8 0.1 0.069 13.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.17 EAU84082.2 - 0.024 14.0 0.1 0.24 10.8 0.0 2.5 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain NACHT PF05729.7 EAU84082.2 - 0.028 14.0 0.0 0.072 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.24 EAU84082.2 - 0.031 13.7 0.1 0.2 11.1 0.0 2.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.17 EAU84082.2 - 0.033 13.0 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EAU84082.2 - 0.066 12.9 0.3 0.7 9.5 0.0 2.6 3 0 0 3 3 3 0 NTPase PhoH PF02562.11 EAU84082.2 - 0.07 12.3 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.8 EAU84082.2 - 0.19 10.4 0.0 0.34 9.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus CBM_1 PF00734.13 EAU84083.1 - 1.7e-11 43.5 16.0 1.7e-11 43.5 11.1 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 EAU84083.1 - 3.4e-06 26.8 0.0 6.6e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAU84083.1 - 1.4e-05 24.6 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EAU84083.1 - 4.6e-05 23.4 0.0 0.00011 22.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU84083.1 - 0.0013 17.9 0.2 0.0025 17.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EAU84083.1 - 0.0015 17.8 0.0 0.0034 16.6 0.0 1.5 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 EAU84083.1 - 0.0026 17.2 0.4 0.017 14.5 0.3 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EAU84083.1 - 0.031 13.8 0.0 0.15 11.5 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2156 PF09924.4 EAU84084.1 - 1.3e-12 47.2 0.0 5.7e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2156) Acetyltransf_10 PF13673.1 EAU84084.1 - 0.032 14.3 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cu_amine_oxid PF01179.15 EAU84085.1 - 2.6e-107 359.1 7.5 4.2e-107 358.4 5.2 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EAU84085.1 - 3.6e-21 74.8 0.0 8.3e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EAU84085.1 - 0.051 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain GPI-anchored PF10342.4 EAU84087.1 - 1.4e-06 28.6 0.9 2.9e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family UCH PF00443.24 EAU84089.2 - 3.6e-09 36.1 0.0 7.4e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Osmo_CC PF08946.5 EAU84089.2 - 0.072 13.1 0.5 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil MerR-DNA-bind PF09278.6 EAU84089.2 - 0.28 11.6 0.2 0.28 11.6 0.1 2.4 2 0 0 2 2 2 0 MerR, DNA binding F-box-like PF12937.2 EAU84090.2 - 6.3e-06 25.8 0.9 2.5e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EAU84090.2 - 4.7e-05 22.9 1.7 0.0077 15.8 0.0 3.6 4 0 0 4 4 4 2 F-box domain DUF775 PF05603.7 EAU84093.2 - 3.4e-21 75.7 0.0 3.7e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) F-box PF00646.28 EAU84094.1 - 1.1e-09 37.7 1.2 2.2e-09 36.7 0.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU84094.1 - 1.3e-07 31.2 0.7 2.5e-07 30.2 0.5 1.5 1 0 0 1 1 1 1 F-box-like Thaumatin PF00314.12 EAU84097.1 - 3e-63 213.1 3.4 3.4e-63 212.9 2.3 1.0 1 0 0 1 1 1 1 Thaumatin family Thaumatin PF00314.12 EAU84098.2 - 1e-63 214.6 5.6 1.2e-63 214.4 3.9 1.0 1 0 0 1 1 1 1 Thaumatin family Glucan_synthase PF02364.10 EAU84099.2 - 0 1372.7 0.1 0 1372.3 0.1 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EAU84099.2 - 2.7e-39 133.7 0.0 6.6e-39 132.4 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Velvet PF11754.3 EAU84100.2 - 8.2e-28 97.3 0.0 1.7e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Velvet factor Sod_Fe_C PF02777.13 EAU84101.2 - 1.7e-38 130.6 0.2 3.4e-38 129.7 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EAU84101.2 - 2.7e-31 107.6 3.8 3.1e-31 107.4 1.9 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 EAU84101.2 - 0.1 11.8 0.0 3.3 6.9 0.0 2.3 1 1 1 2 2 2 0 AsmA-like C-terminal region Plus-3 PF03126.13 EAU84104.2 - 1.7e-25 89.1 0.1 2e-24 85.6 0.0 2.6 1 1 1 2 2 2 1 Plus-3 domain WD40 PF00400.27 EAU84105.2 - 4.3e-47 156.3 14.0 2.8e-12 45.9 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAU84105.2 - 4.7e-07 28.9 0.5 0.0017 17.1 0.1 3.4 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EAU84105.2 - 2e-05 22.9 1.5 0.15 10.1 0.1 3.9 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.6 EAU84105.2 - 8.6e-05 21.8 0.2 0.54 9.4 0.0 3.0 2 1 0 3 3 3 2 TUP1-like enhancer of split DUF3312 PF11768.3 EAU84105.2 - 0.069 11.3 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Peptidase_M20 PF01546.23 EAU84106.1 - 1.8e-30 105.8 0.0 3.2e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAU84106.1 - 2.8e-15 56.0 0.0 4.5e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain FMN_red PF03358.10 EAU84106.1 - 0.047 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase SUZ PF12752.2 EAU84107.1 - 5.1e-16 58.9 2.7 5.1e-16 58.9 1.9 3.7 4 1 0 4 4 4 1 SUZ domain CDC45 PF02724.9 EAU84107.1 - 0.72 7.8 6.0 0.88 7.5 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein UDPG_MGDP_dh_N PF03721.9 EAU84108.2 - 7.3e-57 191.7 0.1 1.4e-56 190.8 0.0 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 EAU84108.2 - 4.3e-35 120.0 0.1 7.4e-34 116.0 0.1 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 EAU84108.2 - 4e-32 110.3 0.0 9.7e-32 109.0 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 EAU84108.2 - 0.0022 17.7 0.3 1.3 8.7 0.0 2.7 2 1 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EAU84108.2 - 0.11 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Thaumatin PF00314.12 EAU84109.1 - 5.9e-63 212.1 8.3 6.6e-63 211.9 5.8 1.0 1 0 0 1 1 1 1 Thaumatin family Pyr_redox_2 PF07992.9 EAU84110.2 - 1.8e-26 93.2 0.0 2.2e-21 76.6 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU84110.2 - 7.6e-11 42.2 0.0 7.6e-11 42.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU84110.2 - 5.1e-06 26.6 0.0 0.0052 16.8 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase WH1 PF00568.18 EAU84111.1 - 2.8e-10 39.9 0.1 2.4e-09 36.9 0.1 2.2 1 1 0 1 1 1 1 WH1 domain PBD PF00786.23 EAU84111.1 - 0.0027 18.0 0.2 0.01 16.2 0.1 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain SAP PF02037.22 EAU84113.1 - 3.9e-06 26.2 0.6 1.1e-05 24.8 0.4 1.8 1 0 0 1 1 1 1 SAP domain LETM1 PF07766.8 EAU84113.1 - 0.15 11.0 0.1 0.28 10.1 0.1 1.3 1 0 0 1 1 1 0 LETM1-like protein Aminotran_1_2 PF00155.16 EAU84115.2 - 1.8e-53 181.7 0.0 2.4e-51 174.8 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EAU84115.2 - 3.5e-05 23.1 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EAU84115.2 - 0.01 14.4 0.0 0.02 13.4 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 EAU84115.2 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Tmemb_18A PF09771.4 EAU84115.2 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 DAO PF01266.19 EAU84116.2 - 1.2e-52 179.0 1.6 4.5e-52 177.1 1.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU84116.2 - 4.6e-05 23.3 0.0 0.00035 20.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 EAU84116.2 - 6.8e-05 22.1 0.0 0.0043 16.2 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.22 EAU84116.2 - 0.0003 21.1 0.0 0.00075 19.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU84116.2 - 0.00063 19.6 0.1 0.67 9.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU84116.2 - 0.0021 16.9 0.5 0.032 13.0 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EAU84116.2 - 0.0061 16.3 0.8 0.063 13.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EAU84116.2 - 0.0063 15.2 0.1 0.1 11.1 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EAU84116.2 - 0.3 9.9 1.2 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pkinase PF00069.20 EAU84121.2 - 3.7e-65 219.6 0.0 4.9e-37 127.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84121.2 - 1.3e-25 89.9 0.3 2.8e-13 49.5 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase DUF3166 PF11365.3 EAU84121.2 - 0.036 14.5 0.1 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) VIT1 PF01988.14 EAU84122.1 - 2.8e-67 226.3 7.1 3.4e-67 226.0 4.9 1.1 1 0 0 1 1 1 1 VIT family 7TMR-DISM_7TM PF07695.6 EAU84122.1 - 0.058 13.0 5.0 0.095 12.3 3.4 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Adeno_E3 PF06040.6 EAU84122.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 protein Aminotran_1_2 PF00155.16 EAU84123.1 - 7.9e-39 133.6 0.0 1.1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Copper-fist PF00649.13 EAU84124.2 - 5.7e-20 70.2 1.5 5.7e-20 70.2 1.0 2.9 1 1 1 2 2 2 1 Copper fist DNA binding domain CASP_C PF08172.7 EAU84124.2 - 0.05 12.6 3.3 0.11 11.4 2.3 1.5 1 0 0 1 1 1 0 CASP C terminal WD40 PF00400.27 EAU84125.2 - 4.3e-32 108.8 2.7 6.5e-08 32.1 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat YiaAB PF05360.9 EAU84125.2 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 yiaA/B two helix domain Peptidase_C14 PF00656.17 EAU84126.2 - 2.5e-17 63.3 0.0 3.9e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.27 EAU84127.2 - 3.3e-12 45.7 12.6 0.00044 20.0 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat C1_3 PF07649.7 EAU84127.2 - 0.11 12.5 3.6 0.29 11.2 2.5 1.8 1 0 0 1 1 1 0 C1-like domain PHD PF00628.24 EAU84127.2 - 0.54 9.9 6.4 0.28 10.9 2.5 2.0 2 0 0 2 2 2 0 PHD-finger CDC45 PF02724.9 EAU84127.2 - 0.55 8.2 11.9 0.91 7.4 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CRC_subunit PF08624.5 EAU84128.2 - 1.1e-38 132.2 0.0 2e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit HAT PF02184.11 EAU84129.2 - 3.9e-19 68.0 49.8 8.3e-10 38.2 1.4 11.0 12 1 0 12 12 11 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EAU84129.2 - 1.7e-17 62.2 8.4 0.0078 16.7 0.0 8.4 3 2 6 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EAU84129.2 - 1.7e-11 43.1 0.4 0.68 9.9 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat Suf PF05843.9 EAU84129.2 - 3.6e-10 40.0 4.6 1e-05 25.4 0.1 3.5 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EAU84129.2 - 2.2e-09 36.7 0.2 0.24 11.0 0.0 4.4 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 EAU84129.2 - 1.3e-08 35.3 14.6 0.014 16.0 0.0 5.6 4 3 4 8 8 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 EAU84129.2 - 2.3e-08 34.2 0.0 0.044 14.1 0.0 5.1 3 2 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU84129.2 - 1e-05 25.3 1.8 0.37 10.7 0.1 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU84129.2 - 0.00035 20.0 0.0 9.3 6.0 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.1 EAU84129.2 - 0.00082 18.6 0.3 0.013 14.6 0.1 2.6 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP U3_assoc_6 PF08640.6 EAU84129.2 - 0.0054 16.4 12.6 0.021 14.5 0.3 4.9 5 2 1 6 6 6 1 U3 small nucleolar RNA-associated protein 6 Mad3_BUB1_I PF08311.7 EAU84129.2 - 0.006 16.3 17.9 0.95 9.2 0.4 6.2 2 2 2 4 4 4 2 Mad3/BUB1 homology region 1 TPR_7 PF13176.1 EAU84129.2 - 0.011 15.4 12.7 2.9 7.9 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAU84129.2 - 0.013 15.3 2.5 7.1 6.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4375 PF14300.1 EAU84129.2 - 1.9 8.4 6.1 20 5.1 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) TPR_6 PF13174.1 EAU84129.2 - 2.3 8.8 7.3 1e+02 3.6 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Radial_spoke_3 PF06098.6 EAU84130.2 - 0.081 11.9 1.8 0.11 11.4 1.2 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 DUF2217 PF10265.4 EAU84130.2 - 0.31 9.7 9.7 0.39 9.4 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 EAU84130.2 - 9.5 4.3 10.9 11 4.1 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-rbx1 PF12678.2 EAU84133.2 - 1.2e-34 118.2 13.5 1.4e-34 117.9 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EAU84133.2 - 1.4e-16 60.0 9.6 2e-16 59.6 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EAU84133.2 - 1.7e-06 27.7 12.9 8.4e-06 25.5 9.0 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAU84133.2 - 0.0011 18.5 11.8 0.02 14.5 8.2 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU84133.2 - 0.004 16.7 9.9 0.41 10.3 7.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU84133.2 - 0.049 13.6 12.5 1.2 9.1 8.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EAU84133.2 - 0.22 11.5 9.3 0.79 9.7 6.5 1.8 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EAU84133.2 - 1.1 9.0 7.0 1.3 8.8 1.6 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 EAU84133.2 - 1.2 8.9 10.7 7.1 6.4 7.4 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EAU84133.2 - 1.8 8.8 9.8 60 3.8 6.4 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain TBCC PF07986.7 EAU84134.1 - 5.6e-21 74.1 0.9 3.1e-20 71.7 0.6 2.0 1 1 0 1 1 1 1 Tubulin binding cofactor C Cob_adeno_trans PF01923.13 EAU84134.1 - 0.0028 17.4 0.1 0.0044 16.8 0.1 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase PROL5-SMR PF15621.1 EAU84135.2 - 0.51 10.8 12.5 0.95 9.9 8.6 1.6 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family HSP20 PF00011.16 EAU84136.1 - 3.3e-15 55.7 0.0 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family CSTF2_hinge PF14327.1 EAU84137.1 - 7.9e-11 41.9 1.0 7.9e-11 41.9 0.7 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EAU84137.1 - 9.7e-09 34.3 2.5 2.9e-08 32.8 1.8 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Baculo_PEP_N PF04512.7 EAU84137.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF605 PF04652.11 EAU84137.1 - 4 6.7 19.5 4.5 6.5 13.5 1.1 1 0 0 1 1 1 0 Vta1 like UQ_con PF00179.21 EAU84139.1 - 2.5e-12 46.4 0.0 6.9e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme VPS9 PF02204.13 EAU84140.2 - 2.2e-18 66.1 0.0 6.2e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain Glypican PF01153.14 EAU84140.2 - 0.63 8.5 4.4 1.4 7.4 3.0 1.5 1 0 0 1 1 1 0 Glypican Spt5_N PF11942.3 EAU84140.2 - 8.1 7.1 17.9 25 5.5 7.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Myosin_tail_1 PF01576.14 EAU84144.2 - 0.0011 16.8 5.3 0.0016 16.2 3.6 1.2 1 0 0 1 1 1 1 Myosin tail SlyX PF04102.7 EAU84144.2 - 0.051 13.9 1.9 0.051 13.9 1.3 2.2 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.14 EAU84144.2 - 0.057 11.2 2.9 0.075 10.8 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EAU84144.2 - 0.13 11.8 3.4 0.29 10.7 2.3 1.5 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EAU84144.2 - 0.2 12.1 2.1 0.39 11.1 1.4 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EAU84144.2 - 0.34 10.4 4.1 0.71 9.4 2.8 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF1664 PF07889.7 EAU84144.2 - 0.64 9.8 2.6 0.9 9.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PHP PF02811.14 EAU84145.2 - 5.8e-13 49.0 0.1 7.5e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 PHP domain DUF1308 PF07000.6 EAU84147.2 - 2.2e-20 72.6 0.0 1.5e-19 69.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) Mito_carr PF00153.22 EAU84148.2 - 9e-66 217.6 0.0 2.3e-24 84.9 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EAU84149.1 - 1.1e-28 100.0 0.0 1.9e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84149.1 - 1.6e-15 56.8 0.0 2.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAU84149.1 - 5e-05 22.4 0.0 8.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU84149.1 - 0.00078 19.2 0.1 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EAU84149.1 - 0.042 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EAU84150.2 - 1.8e-19 69.9 0.0 3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EAU84150.2 - 1.4e-16 59.5 17.2 1.6e-08 34.1 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.17 EAU84150.2 - 1e-12 46.9 6.3 0.00066 19.5 0.1 5.1 4 0 0 4 4 4 3 HEAT repeat Pkinase_Tyr PF07714.12 EAU84150.2 - 5.9e-07 28.8 0.0 3.4e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EAU84150.2 - 6.3e-07 29.5 0.4 0.0039 17.4 0.0 3.0 2 1 0 2 2 2 2 HEAT repeats Nucleoporin_N PF08801.6 EAU84150.2 - 0.0023 16.7 3.8 1.4 7.6 0.4 3.8 2 1 1 3 3 3 2 Nup133 N terminal like HEAT_EZ PF13513.1 EAU84150.2 - 0.0032 17.8 0.8 0.12 12.9 0.3 3.0 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.2 EAU84150.2 - 0.019 14.8 2.4 4.9 6.9 0.1 3.0 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EAU84150.2 - 0.035 14.0 2.0 11 6.0 0.2 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.2 EAU84150.2 - 0.051 13.9 0.5 20 5.6 0.1 2.7 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EAU84150.2 - 0.076 11.3 2.6 0.23 9.7 0.4 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Peptidase_S41 PF03572.13 EAU84152.2 - 6.7e-05 22.3 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 Abhydrolase_6 PF12697.2 EAU84154.1 - 1.1e-18 68.0 0.1 1.5e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU84154.1 - 1.7e-07 31.0 0.0 3.7e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU84154.1 - 2.9e-05 23.8 0.0 8.6e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU84154.1 - 0.00082 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.8 EAU84154.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EAU84154.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.8 EAU84154.1 - 0.16 10.2 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II NYN PF01936.13 EAU84160.2 - 2.2e-05 24.7 0.0 3.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NYN domain Glyco_hydro_46 PF01374.13 EAU84160.2 - 0.14 11.6 0.4 0.21 11.0 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 NYN PF01936.13 EAU84161.2 - 2.6e-09 37.5 0.0 5.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 NYN domain Abhydrolase_2 PF02230.11 EAU84164.1 - 3.5e-06 26.6 0.2 0.0036 16.7 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EAU84164.1 - 0.00057 19.8 0.8 0.0023 17.8 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU84164.1 - 0.00077 19.2 0.1 0.0056 16.4 0.0 2.0 1 1 0 3 3 3 1 Alpha/beta hydrolase family DUF4219 PF13961.1 EAU84165.2 - 0.14 11.6 0.3 0.35 10.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Y_phosphatase PF00102.22 EAU84174.2 - 0.054 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF871 PF05913.6 EAU84174.2 - 1.3 7.7 3.7 1.4 7.6 0.7 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF871) Fib_alpha PF08702.5 EAU84181.2 - 4.1e-05 23.7 0.9 0.00011 22.2 0.6 1.7 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Drf_GBD PF06371.8 EAU84181.2 - 4.8 6.4 7.7 0.098 12.0 0.3 1.8 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Nop14 PF04147.7 EAU84182.2 - 0.062 11.2 16.5 0.1 10.5 11.4 1.2 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.8 EAU84182.2 - 0.35 10.3 5.9 0.79 9.2 4.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 zf-B_box PF00643.19 EAU84183.2 - 1 9.3 6.8 1.4 8.8 3.1 2.4 2 0 0 2 2 2 0 B-box zinc finger Tet_JBP PF12851.2 EAU84185.2 - 1.5e-13 50.3 0.0 2.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Mrr_N PF14338.1 EAU84189.1 - 0.049 13.7 0.2 0.31 11.1 0.2 2.0 2 0 0 2 2 2 0 Mrr N-terminal domain LEA_3 PF03242.8 EAU84189.1 - 0.072 13.3 1.6 0.14 12.4 1.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein PIF1 PF05970.9 EAU84190.2 - 8.8e-25 87.4 0.1 2.2e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Helitron_like_N PF14214.1 EAU84190.2 - 1e-12 48.1 0.0 1.8e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU84190.2 - 5.1e-09 36.0 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU84190.2 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EAU84190.2 - 0.13 11.1 0.1 0.3 9.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Nop14 PF04147.7 EAU84192.2 - 1.9e-248 826.6 16.2 2.4e-248 826.3 11.2 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.8 EAU84192.2 - 0.049 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Noc2p family PAP_central PF04928.12 EAU84193.2 - 5.5e-105 349.7 0.0 8.1e-105 349.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EAU84193.2 - 9.7e-44 148.6 0.0 1.5e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EAU84193.2 - 2e-09 37.6 0.0 4.7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EAU84193.2 - 0.011 13.3 0.0 0.019 12.5 0.0 1.2 1 0 0 1 1 1 0 Nrap protein Mgm101p PF06420.7 EAU84195.1 - 4.9e-92 305.9 0.0 6.3e-92 305.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PI3_PI4_kinase PF00454.22 EAU84196.2 - 5.3e-49 166.8 0.0 1.1e-48 165.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EAU84196.2 - 7e-28 97.6 0.0 2.2e-27 95.9 0.0 1.8 2 0 0 2 2 2 1 FAT domain UME PF08064.8 EAU84196.2 - 8.3e-19 67.5 0.0 6e-18 64.7 0.0 2.6 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 EAU84196.2 - 1.3e-10 40.4 0.1 4e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 EAU84196.2 - 1.3e-05 25.2 0.0 0.0016 18.4 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) TPR_19 PF14559.1 EAU84196.2 - 0.021 15.1 0.0 0.6 10.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat YEATS PF03366.11 EAU84197.1 - 6e-33 112.4 0.0 9.6e-33 111.7 0.0 1.3 1 0 0 1 1 1 1 YEATS family Bap31 PF05529.7 EAU84197.1 - 0.059 12.8 1.0 0.085 12.3 0.7 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like COX7a PF02238.10 EAU84198.1 - 0.0027 17.3 0.0 0.0038 16.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIa Thioredoxin_4 PF13462.1 EAU84200.1 - 4.4e-12 46.3 0.0 7e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EAU84200.1 - 0.019 14.5 0.0 0.15 11.6 0.0 2.2 2 1 0 2 2 2 0 DSBA-like thioredoxin domain PCI PF01399.22 EAU84202.2 - 1.2e-12 48.1 0.0 2.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain Cyclin_N PF00134.18 EAU84203.1 - 1.3e-05 24.7 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain IU_nuc_hydro PF01156.14 EAU84204.2 - 2.9e-84 282.9 0.0 3.3e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_S28 PF05577.7 EAU84205.2 - 1.2e-43 149.2 0.0 2.6e-31 108.6 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 EAU84205.2 - 0.055 11.9 0.0 0.11 10.9 0.0 1.4 1 0 0 1 1 1 0 PS-10 peptidase S37 WD40 PF00400.27 EAU84207.2 - 2.5e-08 33.4 3.4 0.0065 16.3 0.8 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat CDK5_activator PF03261.10 EAU84207.2 - 2.9 7.1 6.2 3.7 6.7 4.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF605 PF04652.11 EAU84207.2 - 3.4 6.9 18.2 4.9 6.4 12.6 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EAU84207.2 - 4.7 7.0 11.4 6.7 6.5 7.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.8 EAU84207.2 - 6.5 6.0 6.7 9.1 5.5 4.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PAT1 PF09770.4 EAU84207.2 - 7.8 4.5 15.9 9.9 4.2 11.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sulfate_transp PF00916.15 EAU84208.2 - 9.8e-55 185.5 11.7 9.8e-55 185.5 8.1 2.4 2 1 1 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EAU84208.2 - 1.6e-27 95.0 4.7 1.6e-27 95.0 3.3 3.0 2 1 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EAU84208.2 - 2e-18 65.9 0.0 3.9e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EAU84208.2 - 0.046 13.7 0.0 0.21 11.6 0.0 2.2 1 1 0 1 1 1 0 STAS domain TFIID-18kDa PF02269.11 EAU84209.1 - 1.7e-32 111.1 0.1 3e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Ribosomal_L39 PF00832.15 EAU84209.1 - 0.73 9.3 3.3 0.74 9.3 0.5 2.1 2 0 0 2 2 2 0 Ribosomal L39 protein Asp_protease PF09668.5 EAU84210.1 - 1.2e-58 196.0 0.1 2.2e-58 195.2 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EAU84210.1 - 1.3e-10 41.6 0.0 4e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EAU84210.1 - 7.7e-09 34.8 0.0 1.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 EAU84210.1 - 4.9e-06 26.2 0.1 6.6e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 EAU84210.1 - 9.4e-06 25.3 2.0 1.3e-05 24.9 0.0 2.3 3 0 0 3 3 3 1 UBA/TS-N domain RVP_2 PF08284.6 EAU84210.1 - 2.2e-05 24.3 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease XPC-binding PF09280.6 EAU84210.1 - 0.00053 19.3 0.9 0.0012 18.3 0.6 1.6 1 0 0 1 1 1 1 XPC-binding domain RVP PF00077.15 EAU84210.1 - 0.0014 18.4 0.0 0.0059 16.4 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 EAU84210.1 - 0.0033 17.0 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 EAU84210.1 - 0.0035 16.8 0.2 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain Peptidase_M8 PF01457.11 EAU84210.1 - 0.11 10.7 0.1 0.15 10.3 0.1 1.1 1 0 0 1 1 1 0 Leishmanolysin HMG_box PF00505.14 EAU84211.1 - 1e-11 44.9 0.4 1.8e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU84211.1 - 0.00017 21.8 0.1 0.00035 20.8 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain Cyclase PF04199.8 EAU84212.2 - 7.9e-26 90.7 0.0 1e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase PEPCK_ATP PF01293.15 EAU84212.2 - 0.12 10.9 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase zf-MYND PF01753.13 EAU84213.1 - 2e-07 30.7 10.5 3.6e-07 29.9 7.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU84213.1 - 0.05 13.4 1.0 1 9.2 0.8 2.7 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 VWA_2 PF13519.1 EAU84215.2 - 0.00012 22.2 0.0 0.00032 20.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain F-box-like PF12937.2 EAU84217.2 - 1.4e-06 27.9 0.1 3.9e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU84217.2 - 0.043 13.4 0.2 13 5.5 0.0 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) CNH PF00780.17 EAU84218.2 - 0.00062 19.2 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 CNH domain VWA_2 PF13519.1 EAU84219.1 - 4.6e-08 33.3 0.0 8.6e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EAU84219.1 - 2.8e-07 30.5 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EAU84219.1 - 6.5e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Thr_synth_N PF14821.1 EAU84219.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Threonine synthase N terminus TRP PF06011.7 EAU84220.2 - 1.3e-43 149.1 30.2 2.9e-42 144.7 20.9 2.4 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EAU84220.2 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain GFA PF04828.9 EAU84221.2 - 2.5e-16 59.3 1.6 3.9e-09 36.3 0.0 3.1 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27 PF01599.14 EAU84221.2 - 0.07 12.9 0.3 0.79 9.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a DUF1768 PF08719.6 EAU84223.2 - 5.8e-26 91.1 0.0 8.5e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Sigma70_ner PF04546.8 EAU84223.2 - 0.0066 16.0 0.9 1.8 8.1 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, non-essential region Pox_Ag35 PF03286.9 EAU84223.2 - 0.35 10.3 2.4 0.83 9.1 0.7 2.1 2 1 0 2 2 2 0 Pox virus Ag35 surface protein DUF1768 PF08719.6 EAU84225.2 - 4e-05 23.4 0.0 0.0053 16.5 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF1768) F-box-like PF12937.2 EAU84227.1 - 3.7e-08 32.9 0.7 3.7e-08 32.9 0.5 1.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU84228.2 - 2.1e-12 46.5 1.4 4.6e-12 45.4 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU84228.2 - 0.0023 17.5 0.4 0.015 14.9 0.3 2.4 1 1 0 1 1 1 1 F-box domain RRM_1 PF00076.17 EAU84229.1 - 5.1e-26 90.1 0.1 5.6e-12 45.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84229.1 - 1e-25 89.4 0.0 1.6e-11 44.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU84229.1 - 1.3e-09 37.7 0.0 0.00052 19.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU84229.1 - 0.0035 17.0 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Hid1 PF12722.2 EAU84229.1 - 4.3 4.8 11.4 5.7 4.4 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ofd1_CTDD PF10637.4 EAU84230.2 - 2.1e-86 289.3 0.0 1.4e-82 276.8 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EAU84230.2 - 3.3e-15 56.4 0.8 3.8e-14 52.9 0.0 2.8 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EAU84231.2 - 8.1e-38 130.1 0.0 1.2e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 ATG22 PF11700.3 EAU84232.2 - 2.5e-89 299.9 28.4 7e-89 298.4 19.7 1.6 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EAU84232.2 - 1e-07 31.0 37.1 2e-06 26.7 5.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily GST_N_3 PF13417.1 EAU84233.2 - 8.8e-24 83.5 0.0 2e-23 82.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU84233.2 - 3.6e-15 55.7 0.0 1.3e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DUF1768 PF08719.6 EAU84233.2 - 9e-11 41.7 0.0 2.5e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) GST_N PF02798.15 EAU84233.2 - 0.00018 21.5 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EAU84233.2 - 0.01 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin DUF4131 PF13567.1 EAU84233.2 - 0.087 12.2 1.0 0.55 9.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Yip1 PF04893.12 EAU84233.2 - 0.18 11.2 4.8 0.4 10.1 3.3 1.6 1 0 0 1 1 1 0 Yip1 domain DUF2207 PF09972.4 EAU84233.2 - 0.31 9.5 0.1 18 3.7 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) F-box-like PF12937.2 EAU84234.2 - 2.5e-09 36.7 0.8 7.9e-09 35.1 0.6 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU84234.2 - 0.001 18.5 1.9 4.4 7.0 0.2 4.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EAU84234.2 - 0.13 11.9 1.0 1 9.0 0.0 2.8 2 0 0 2 2 2 0 F-box domain FlgN PF05130.7 EAU84235.2 - 0.0017 18.6 0.0 0.0017 18.6 0.0 2.9 3 0 0 3 3 3 1 FlgN protein IncA PF04156.9 EAU84235.2 - 0.0017 17.9 5.0 0.0017 17.9 3.5 2.6 3 0 0 3 3 2 1 IncA protein TPR_MLP1_2 PF07926.7 EAU84235.2 - 0.082 12.6 19.1 0.51 10.0 1.2 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Hormone_1 PF00103.15 EAU84235.2 - 0.085 12.1 6.3 0.51 9.6 0.7 2.4 2 0 0 2 2 2 0 Somatotropin hormone family BLOC1_2 PF10046.4 EAU84235.2 - 0.12 12.4 9.8 0.22 11.7 2.8 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PEP-utilisers_N PF05524.8 EAU84235.2 - 0.14 11.9 5.0 0.28 10.9 1.2 2.5 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Spc7 PF08317.6 EAU84235.2 - 0.14 10.7 16.8 0.038 12.6 6.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4071 PF13281.1 EAU84235.2 - 0.33 9.7 3.7 0.7 8.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) Macoilin PF09726.4 EAU84235.2 - 0.34 9.1 10.2 0.045 12.0 3.7 1.8 2 0 0 2 2 2 0 Transmembrane protein V_ATPase_I PF01496.14 EAU84235.2 - 0.57 7.9 10.9 0.9 7.3 2.2 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EAU84235.2 - 0.8 8.6 18.6 1.2 8.1 7.9 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 EAU84235.2 - 0.93 8.6 17.3 0.53 9.4 6.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PA26 PF04636.8 EAU84235.2 - 0.95 8.0 3.5 0.59 8.7 1.1 1.4 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF972 PF06156.8 EAU84235.2 - 1.2 9.5 12.9 48 4.3 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF972) DUF1759 PF03564.10 EAU84235.2 - 2 8.2 6.1 0.49 10.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Herpes_UL6 PF01763.11 EAU84235.2 - 2.1 6.4 9.4 1 7.4 0.2 2.1 2 0 0 2 2 2 0 Herpesvirus UL6 like TBPIP PF07106.8 EAU84235.2 - 2.7 7.5 16.2 0.97 8.9 5.7 2.3 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4407 PF14362.1 EAU84235.2 - 2.7 6.8 13.2 0.054 12.4 3.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin PF00804.20 EAU84235.2 - 2.8 8.1 13.4 4.9 7.3 0.2 2.6 2 0 0 2 2 2 0 Syntaxin TMF_DNA_bd PF12329.3 EAU84235.2 - 3 7.7 29.2 1.3 8.8 5.3 3.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding GrpE PF01025.14 EAU84235.2 - 3.8 7.0 13.3 8.1 5.9 0.4 2.4 2 0 0 2 2 2 0 GrpE Lge1 PF11488.3 EAU84235.2 - 4 7.6 8.5 16 5.8 2.3 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Atg14 PF10186.4 EAU84235.2 - 4.6 6.1 10.5 0.38 9.6 2.5 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ACCA PF03255.9 EAU84235.2 - 5.2 6.6 8.3 17 4.9 1.4 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Shugoshin_N PF07558.6 EAU84235.2 - 5.3 6.8 11.3 0.24 11.1 0.5 3.0 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.7 EAU84235.2 - 6.8 6.5 10.5 10 5.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.7 EAU84235.2 - 7 6.8 19.8 1.1 9.4 1.3 3.1 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Spc24 PF08286.6 EAU84235.2 - 9.3 5.9 20.6 0.99 9.1 2.5 3.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Phage_XkdX PF09693.5 EAU84236.2 - 0.037 13.5 0.3 0.062 12.8 0.2 1.3 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Cyt-b5 PF00173.23 EAU84237.1 - 3.5e-25 87.6 0.0 4.4e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribonucleas_3_3 PF14622.1 EAU84240.2 - 4.5e-15 55.7 0.0 6.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EAU84240.2 - 2.5e-13 50.4 0.0 4.9e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EAU84240.2 - 6.5e-07 29.8 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif FAD_binding_4 PF01565.18 EAU84241.1 - 2.5e-30 104.7 6.8 2.5e-30 104.7 3.4 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EAU84241.1 - 1.8e-07 30.9 0.0 4.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like PAPS_reduct PF01507.14 EAU84242.1 - 2.6e-37 128.3 0.0 8e-37 126.7 0.0 1.7 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PNP_UDP_1 PF01048.15 EAU84243.2 - 0.17 10.8 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 Phosphorylase superfamily F-box-like PF12937.2 EAU84245.2 - 2.8e-09 36.5 0.4 2.8e-09 36.5 0.3 2.2 2 0 0 2 2 2 1 F-box-like VEFS-Box PF09733.4 EAU84245.2 - 0.11 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein Ham1p_like PF01725.11 EAU84251.2 - 1.3e-51 174.6 0.0 1.5e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_M28 PF04389.12 EAU84252.1 - 5.2e-27 94.7 0.1 7.9e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAU84252.1 - 8.3e-07 28.6 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L11 PF00298.14 EAU84253.1 - 1.7e-27 95.3 0.3 2.6e-27 94.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EAU84253.1 - 2.9e-27 93.8 0.2 5.1e-27 93.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain HisKA_2 PF07568.7 EAU84256.2 - 0.066 13.0 0.3 0.24 11.2 0.2 2.0 1 1 1 2 2 2 0 Histidine kinase Glyco_hydro_cc PF11790.3 EAU84257.1 - 3.8e-63 213.0 0.8 4.7e-63 212.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF4106 PF13388.1 EAU84257.1 - 7.1 5.4 14.2 9.7 5.0 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RRM_1 PF00076.17 EAU84258.1 - 3.4e-30 103.4 0.0 9.9e-15 53.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84258.1 - 1.5e-22 79.3 0.0 5.6e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU84258.1 - 3.7e-11 42.6 0.0 7.1e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAU84258.1 - 0.0016 18.1 3.1 2.1 8.1 0.4 3.2 3 0 0 3 3 3 2 Limkain b1 DbpA PF03880.10 EAU84258.1 - 0.013 15.1 0.1 0.98 9.1 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain OB_RNB PF08206.6 EAU84258.1 - 0.026 14.0 1.7 6.8 6.2 0.5 3.3 2 1 0 2 2 2 0 Ribonuclease B OB domain Sigma70_ECF PF07638.6 EAU84258.1 - 0.06 13.0 0.2 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 ECF sigma factor Menin PF05053.8 EAU84258.1 - 6 4.9 13.8 10 4.1 9.6 1.3 1 0 0 1 1 1 0 Menin DUF4187 PF13821.1 EAU84259.1 - 3.5e-21 74.5 0.8 3.5e-21 74.5 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EAU84259.1 - 6.7e-06 25.7 0.3 6.7e-06 25.7 0.2 2.6 3 0 0 3 3 3 1 G-patch domain DUF3425 PF11905.3 EAU84262.2 - 1.7e-20 73.3 2.2 2e-18 66.5 0.4 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EAU84262.2 - 2e-07 30.8 9.5 2e-07 30.8 6.6 3.1 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EAU84262.2 - 0.015 15.0 6.0 0.015 15.0 4.2 3.0 2 1 1 3 3 3 0 Basic region leucine zipper Ribosomal_S14 PF00253.16 EAU84263.1 - 1.8e-18 65.6 0.5 2.9e-18 64.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MFS_1 PF07690.11 EAU84264.2 - 2.9e-07 29.5 3.9 3.2e-05 22.8 0.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EAU84265.2 - 1e-69 234.5 0.0 1.4e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84265.2 - 7.4e-30 103.8 0.1 6.5e-29 100.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU84265.2 - 2.7e-08 33.1 0.2 1.4e-05 24.2 0.0 2.8 2 1 0 2 2 2 2 Kinase-like APH PF01636.18 EAU84265.2 - 0.046 13.4 0.0 1.5 8.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EAU84265.2 - 0.051 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.12 EAU84266.2 - 1.4e-20 73.3 0.4 2.5e-19 69.3 0.0 2.4 2 0 0 2 2 2 1 HSF-type DNA-binding BAF1_ABF1 PF04684.8 EAU84266.2 - 6.2 5.5 21.2 9.9 4.8 14.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SNARE_assoc PF09335.6 EAU84267.2 - 8.3e-14 51.8 9.2 4e-13 49.6 5.6 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2910 PF11139.3 EAU84267.2 - 0.029 13.5 4.7 0.071 12.2 2.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) DUF4231 PF14015.1 EAU84267.2 - 1.5 8.7 6.4 3.4 7.6 2.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) PEX11 PF05648.9 EAU84269.2 - 3e-12 46.2 2.8 8.5e-11 41.5 1.9 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.8 EAU84270.2 - 0.016 15.0 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Tctex-1 family Nop PF01798.13 EAU84273.1 - 5.3e-44 149.1 0.3 9.9e-44 148.2 0.2 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EAU84273.1 - 4.2e-37 127.3 5.3 1e-36 126.1 3.7 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EAU84273.1 - 6.8e-19 67.4 0.1 6e-18 64.3 0.1 2.4 2 0 0 2 2 2 1 NOSIC (NUC001) domain NifU_N PF01592.11 EAU84274.1 - 1.4e-50 170.4 0.0 1.7e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TFIID-31kDa PF02291.10 EAU84275.1 - 5.8e-18 64.9 0.0 8.3e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Myc_N PF01056.13 EAU84275.1 - 3.6 6.6 13.4 2.5 7.2 0.4 2.1 1 1 1 2 2 2 0 Myc amino-terminal region WD40 PF00400.27 EAU84276.2 - 0.00014 21.6 1.7 0.13 12.1 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Mg_trans_NIPA PF05653.9 EAU84277.2 - 3.1e-53 180.7 16.2 3e-35 121.6 6.7 3.1 2 1 1 3 3 3 3 Magnesium transporter NIPA p450 PF00067.17 EAU84278.2 - 1e-57 195.7 0.0 1.3e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nup88 PF10168.4 EAU84279.2 - 1.6e-22 79.2 0.5 2.5e-12 45.5 0.7 2.7 2 1 0 2 2 2 2 Nuclear pore component Mit_KHE1 PF10173.4 EAU84279.2 - 1.9 8.3 5.0 3.7 7.3 3.4 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Proteasome PF00227.21 EAU84280.2 - 1.3e-48 164.8 0.0 1.8e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAU84280.2 - 8.1e-13 47.4 0.2 1.6e-12 46.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PCI_Csn8 PF10075.4 EAU84281.1 - 1.6e-36 125.2 0.2 2.6e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EAU84281.1 - 1.6e-34 119.2 0.0 3.1e-34 118.3 0.0 1.5 1 1 1 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Proteasome PF00227.21 EAU84282.2 - 3.4e-32 111.2 0.0 4.2e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit GFO_IDH_MocA PF01408.17 EAU84284.2 - 7.9e-21 74.7 0.1 1.3e-20 74.0 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAU84284.2 - 4.5e-07 29.6 0.0 1.8e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Sclerostin PF05463.6 EAU84284.2 - 0.0079 15.7 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Sclerostin (SOST) Mito_fiss_Elm1 PF06258.6 EAU84284.2 - 0.035 13.0 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission ELM1 TrkA_N PF02254.13 EAU84284.2 - 0.055 13.4 0.1 0.21 11.6 0.1 1.9 1 1 0 1 1 1 0 TrkA-N domain MukB PF04310.7 EAU84284.2 - 0.07 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 MukB N-terminal Cyt-b5 PF00173.23 EAU84286.1 - 1.4e-08 34.4 0.0 2.5e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.14 EAU84287.2 - 9e-42 141.9 0.0 2.3e-41 140.5 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EAU84287.2 - 2.2e-14 52.9 0.0 1.1e-07 31.4 0.0 2.9 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) HTH_45 PF14947.1 EAU84287.2 - 0.039 13.7 0.1 8.2 6.3 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DUF2458 PF10454.4 EAU84288.2 - 4.2e-10 39.6 0.2 7.2e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DGCR6 PF07324.6 EAU84288.2 - 3.8e-05 23.2 0.1 9e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Abhydrolase_6 PF12697.2 EAU84289.2 - 1.9e-13 50.8 0.1 4.8e-13 49.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU84289.2 - 2.4e-05 24.0 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU84289.2 - 0.0037 17.0 0.0 0.061 13.0 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Epimerase PF01370.16 EAU84290.2 - 2.3e-44 151.5 0.0 3e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAU84290.2 - 3.5e-11 42.5 0.0 4.6e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EAU84290.2 - 3.6e-10 39.0 0.0 4.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU84290.2 - 2e-08 33.4 0.1 0.00022 20.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EAU84290.2 - 7e-07 28.4 0.5 0.00082 18.3 0.2 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EAU84290.2 - 2.8e-05 24.1 0.0 6.8e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EAU84290.2 - 0.071 13.0 0.3 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Bystin PF05291.6 EAU84291.1 - 1.4e-125 418.2 0.0 1.9e-125 417.8 0.0 1.1 1 0 0 1 1 1 1 Bystin SnoaL_2 PF12680.2 EAU84292.2 - 0.001 19.4 0.0 0.0053 17.1 0.0 2.1 1 1 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EAU84292.2 - 0.0013 18.3 0.1 0.055 13.0 0.0 2.4 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase FAD_binding_3 PF01494.14 EAU84293.1 - 5.8e-22 78.2 0.1 1.6e-21 76.7 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EAU84293.1 - 3.8e-06 26.0 0.0 5.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EAU84293.1 - 3.7e-05 22.7 2.3 0.00015 20.8 1.2 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU84293.1 - 4.6e-05 23.3 1.3 0.00012 22.0 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU84293.1 - 0.00079 19.3 0.5 0.0018 18.1 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EAU84293.1 - 0.0025 16.4 1.3 0.26 9.8 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 EAU84293.1 - 0.0041 17.5 0.6 0.01 16.1 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU84293.1 - 0.006 15.4 3.2 0.018 13.9 2.3 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EAU84293.1 - 0.011 14.8 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EAU84293.1 - 0.048 12.5 0.4 0.087 11.6 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EAU84293.1 - 0.061 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EAU84293.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU84293.1 - 0.57 8.5 3.0 0.7 8.2 1.2 1.9 2 1 0 2 2 2 0 HI0933-like protein Ribosomal_L3 PF00297.17 EAU84294.1 - 1.8e-120 401.2 6.0 2.2e-120 400.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_2 PF13041.1 EAU84295.2 - 4.6e-06 26.5 0.0 0.065 13.2 0.0 4.6 4 1 0 4 4 4 2 PPR repeat family PPR_1 PF12854.2 EAU84295.2 - 5.1e-05 22.6 2.2 0.039 13.4 0.2 3.9 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.1 EAU84295.2 - 0.00064 19.8 1.2 69 4.1 0.0 5.4 5 0 0 5 5 5 0 Pentatricopeptide repeat domain Ras PF00071.17 EAU84296.2 - 1.2e-41 141.7 0.0 1.3e-38 131.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EAU84296.2 - 1.6e-14 54.4 0.0 2.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU84296.2 - 4.1e-09 35.9 0.0 9.2e-09 34.7 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAU84296.2 - 0.0084 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EAU84296.2 - 0.0088 15.2 0.1 0.02 14.1 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EAU84296.2 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DAO PF01266.19 EAU84299.1 - 6.4e-45 153.5 0.0 1.5e-44 152.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU84299.1 - 3.6e-05 23.6 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAU84299.1 - 0.015 14.1 0.0 0.047 12.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EAU84299.1 - 0.019 15.0 0.0 0.12 12.4 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EAU84299.1 - 0.032 12.4 0.0 0.082 11.0 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.13 EAU84299.1 - 0.054 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 EAU84299.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EAU84299.1 - 0.082 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU84299.1 - 0.096 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding NDUFA12 PF05071.11 EAU84300.1 - 1.1e-25 90.0 1.7 1.4e-25 89.7 1.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SH3_1 PF00018.23 EAU84301.2 - 5.8e-24 83.2 0.0 1.2e-10 40.5 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EAU84301.2 - 8.8e-18 63.6 0.0 4.9e-08 32.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EAU84301.2 - 1.9e-16 59.2 0.0 9.7e-10 37.7 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EAU84301.2 - 3.4e-06 26.8 0.0 7.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EAU84301.2 - 0.0028 17.2 0.1 0.0057 16.2 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Not3 PF04065.10 EAU84302.2 - 4.8e-93 310.7 28.7 4.8e-93 310.7 19.9 1.5 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EAU84302.2 - 2.5e-44 150.3 5.5 2.5e-44 150.3 3.8 2.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family SmpA_OmlA PF04355.8 EAU84302.2 - 0.035 13.7 0.3 0.26 10.9 0.2 2.5 1 1 0 1 1 1 0 SmpA / OmlA family Syntaxin PF00804.20 EAU84302.2 - 0.4 10.8 18.5 2.3 8.4 1.2 2.9 1 1 0 2 2 2 0 Syntaxin Ribosomal_L12 PF00542.14 EAU84303.2 - 1.9e-20 72.6 4.9 9.8e-19 67.1 2.6 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EAU84303.2 - 0.00053 20.3 3.6 0.00053 20.3 2.5 2.6 3 0 0 3 3 3 1 60s Acidic ribosomal protein Claudin_3 PF06653.6 EAU84304.2 - 6 6.5 12.7 2.5 7.8 1.2 2.8 2 1 0 2 2 2 0 Tight junction protein, Claudin-like p450 PF00067.17 EAU84306.1 - 7.2e-51 173.1 0.0 9.5e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COMPASS-Shg1 PF05205.7 EAU84307.2 - 1.1e-11 44.9 1.4 1.6e-11 44.4 1.0 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF445 PF04286.7 EAU84307.2 - 0.013 15.0 1.0 0.02 14.4 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) SecA_SW PF07516.8 EAU84307.2 - 0.079 12.7 1.3 0.13 11.9 0.9 1.3 1 1 0 1 1 1 0 SecA Wing and Scaffold domain PilO PF04350.8 EAU84307.2 - 0.082 12.7 0.2 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilO URO-D PF01208.12 EAU84308.1 - 2e-126 421.5 0.0 2.3e-126 421.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF2520 PF10728.4 EAU84308.1 - 0.12 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) DSPn PF14671.1 EAU84309.2 - 3.6e-38 130.7 0.0 1.6e-36 125.3 0.0 2.7 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EAU84309.2 - 4.8e-16 58.5 0.0 1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAU84309.2 - 2.5e-05 23.7 0.0 8.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EAU84309.2 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EAU84309.2 - 0.1 12.8 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Ank_2 PF12796.2 EAU84310.2 - 1.5e-20 73.3 0.8 3.4e-09 36.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAU84310.2 - 1.2e-18 65.8 0.8 3.2e-08 32.9 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EAU84310.2 - 5.3e-16 58.2 0.1 3.2e-07 30.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU84310.2 - 7.4e-16 58.1 2.9 3.9e-10 39.9 0.1 4.3 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU84310.2 - 1.6e-15 55.6 1.7 2.9e-05 23.9 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 EAU84310.2 - 8.7e-05 22.1 1.6 0.0018 17.8 0.0 3.3 2 2 1 3 3 3 1 KilA-N domain ATG16 PF08614.6 EAU84310.2 - 0.0033 17.2 5.1 0.41 10.4 0.2 2.4 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) DnaG_DnaB_bind PF08278.6 EAU84310.2 - 0.0079 16.4 3.8 0.023 14.9 2.6 1.7 1 0 0 1 1 1 1 DNA primase DnaG DnaB-binding TMF_TATA_bd PF12325.3 EAU84310.2 - 0.01 15.5 4.1 0.01 15.5 2.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Acyl-CoA_dh_C PF12806.2 EAU84310.2 - 0.013 15.3 1.3 0.41 10.5 0.0 2.8 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like 4HB_MCP_1 PF12729.2 EAU84310.2 - 0.015 14.6 0.9 2.6 7.3 0.2 2.5 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF3122 PF11320.3 EAU84310.2 - 0.029 14.2 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) ABC_tran_2 PF12848.2 EAU84310.2 - 0.74 9.6 5.5 2.1 8.2 3.4 2.1 1 1 0 1 1 1 0 ABC transporter IncA PF04156.9 EAU84310.2 - 1.5 8.3 14.4 3.9 7.0 4.4 2.2 2 0 0 2 2 2 0 IncA protein Bap31 PF05529.7 EAU84310.2 - 2 7.8 5.1 14 5.0 0.1 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like AAA_13 PF13166.1 EAU84310.2 - 2.1 6.6 6.8 4.1 5.7 4.7 1.4 1 1 0 1 1 1 0 AAA domain GAS PF13851.1 EAU84310.2 - 8.7 5.4 11.2 1.2 8.3 1.9 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Aldedh PF00171.17 EAU84311.1 - 7.4 4.7 6.2 11 4.2 4.3 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Nucleoside_tran PF01733.13 EAU84312.2 - 7.8e-41 140.2 3.2 7.8e-41 140.2 2.2 2.1 1 1 0 2 2 2 1 Nucleoside transporter FAD_binding_4 PF01565.18 EAU84314.1 - 2.3e-33 114.6 3.6 4.8e-33 113.5 2.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU84314.1 - 3.7e-08 33.1 2.0 3.7e-08 33.1 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like MRC1 PF09444.5 EAU84315.2 - 1.9e-17 63.9 28.2 1.9e-17 63.9 19.5 6.4 6 2 2 8 8 8 2 MRC1-like domain Acyltransferase PF01553.16 EAU84316.2 - 3e-09 36.4 0.0 4.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Na_Ca_ex PF01699.19 EAU84317.2 - 1.2e-10 41.0 26.7 1.5e-06 27.8 3.1 3.6 2 2 1 3 3 3 2 Sodium/calcium exchanger protein Glyco_hydro_88 PF07470.8 EAU84318.1 - 5.5e-21 74.9 0.2 7.9e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_18 PF00704.23 EAU84319.1 - 1.5e-68 231.8 0.5 2.1e-68 231.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EAU84319.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Peptidase_M28 PF04389.12 EAU84320.2 - 3e-22 79.2 0.0 8.4e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAU84320.2 - 2.5e-05 23.8 0.0 4.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3022 PF11226.3 EAU84320.2 - 0.032 14.1 0.0 0.073 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) Nicastrin PF05450.10 EAU84320.2 - 0.056 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Nicastrin Vac14_Fig4_bd PF11916.3 EAU84321.2 - 4.4e-81 270.3 6.9 7.3e-81 269.6 4.8 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EAU84321.2 - 1.1e-41 141.1 0.1 5.8e-38 129.1 0.0 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EAU84321.2 - 1.9e-12 46.1 0.2 0.0023 17.8 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EAU84321.2 - 4.3e-08 33.4 0.3 0.36 11.3 0.0 6.5 6 1 1 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.1 EAU84321.2 - 5.8e-07 29.7 0.0 1.7 9.0 0.0 4.7 4 0 0 4 4 4 3 HEAT repeats CLASP_N PF12348.3 EAU84321.2 - 0.00011 21.6 1.3 11 5.2 0.0 4.7 5 1 0 5 5 5 2 CLASP N terminal Cnd1 PF12717.2 EAU84321.2 - 0.03 14.1 1.5 2.4 7.9 0.0 3.3 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 EAU84321.2 - 0.077 13.1 0.0 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1546) DUF2120 PF09893.4 EAU84321.2 - 0.086 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Y_phosphatase3 PF13350.1 EAU84322.2 - 1.9e-51 174.6 0.0 3.1e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EAU84322.2 - 2.8e-15 56.1 0.1 7.5e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EAU84322.2 - 0.033 13.5 0.0 0.069 12.5 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EAU84322.2 - 0.041 13.2 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MCM PF00493.18 EAU84323.1 - 2.1e-137 457.3 1.5 3.1e-137 456.8 1.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAU84323.1 - 1.8e-21 76.8 0.3 1e-20 74.4 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAU84323.1 - 5.1e-08 32.3 0.0 8.1e-07 28.4 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EAU84323.1 - 0.0011 18.4 0.0 0.004 16.6 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EAU84323.1 - 0.0024 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAU84323.1 - 0.023 14.4 0.0 0.076 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ank_2 PF12796.2 EAU84324.2 - 5.3e-51 170.9 12.7 4.3e-17 62.2 0.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Pex2_Pex12 PF04757.9 EAU84324.2 - 5e-49 166.7 9.1 7.7e-49 166.1 6.3 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Ank_4 PF13637.1 EAU84324.2 - 4.6e-38 128.9 9.5 2.7e-11 43.6 0.3 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EAU84324.2 - 1.4e-35 119.2 20.1 4.5e-06 26.2 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.1 EAU84324.2 - 2.4e-27 92.2 8.9 0.00017 21.4 0.0 8.1 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EAU84324.2 - 7.7e-23 80.0 22.8 6e-08 32.6 0.3 7.6 3 1 6 9 9 9 6 Ankyrin repeats (many copies) SPX PF03105.14 EAU84324.2 - 1.4e-18 67.6 0.1 3.1e-16 59.9 0.0 2.2 2 0 0 2 2 2 1 SPX domain GDPD PF03009.12 EAU84324.2 - 2.2e-10 40.4 0.0 4.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-C3HC4_2 PF13923.1 EAU84324.2 - 1.5e-07 31.3 2.2 3.9e-07 29.9 1.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU84324.2 - 2.2e-06 27.2 1.0 5.2e-06 26.0 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU84324.2 - 2.1e-05 24.2 1.0 2.1e-05 24.2 0.7 2.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU84324.2 - 0.011 15.5 2.5 0.025 14.4 1.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UPF0547 PF10571.4 EAU84324.2 - 0.067 12.8 1.5 0.15 11.8 1.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C3HC4 PF00097.20 EAU84324.2 - 0.08 12.6 1.9 0.18 11.5 1.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU84324.2 - 0.27 10.9 2.0 0.81 9.4 1.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EAU84324.2 - 6.7 6.3 6.1 1.5e+02 2.0 4.9 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ABC_tran PF00005.22 EAU84325.2 - 4.6e-24 85.2 0.0 1.2e-23 83.8 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU84325.2 - 4.1e-05 23.7 0.1 0.0072 16.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EAU84325.2 - 0.0031 17.5 0.1 0.017 15.1 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EAU84325.2 - 0.0031 17.7 0.0 0.029 14.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EAU84325.2 - 0.0063 16.4 0.0 3.7 7.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EAU84325.2 - 0.0082 15.8 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EAU84325.2 - 0.0082 15.6 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EAU84325.2 - 0.0085 16.9 0.0 0.02 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EAU84325.2 - 0.011 15.0 0.0 0.26 10.5 0.0 2.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EAU84325.2 - 0.017 13.6 0.0 0.39 9.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EAU84325.2 - 0.025 14.6 0.0 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAU84325.2 - 0.037 13.1 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 EAU84325.2 - 0.045 14.0 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAU84325.2 - 0.059 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EAU84325.2 - 0.065 13.1 0.1 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAU84325.2 - 0.097 12.4 0.2 0.38 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EAU84325.2 - 0.15 11.0 0.1 0.55 9.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 EAU84325.2 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-Di19 PF05605.7 EAU84327.2 - 0.02 15.0 1.3 3.4 7.8 0.0 3.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.1 EAU84327.2 - 0.11 12.1 1.3 3.5 7.3 0.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BCAS2 PF05700.6 EAU84327.2 - 0.33 10.3 5.4 0.075 12.4 0.8 2.0 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Tom7 PF08038.7 EAU84328.1 - 9.9e-20 69.7 0.2 1.1e-19 69.5 0.2 1.1 1 0 0 1 1 1 1 TOM7 family JAB PF01398.16 EAU84329.1 - 1.9e-21 75.9 0.3 3.7e-21 75.0 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EAU84329.1 - 1.5e-12 47.6 0.0 3.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UreF PF01730.11 EAU84330.1 - 6.3e-16 58.7 0.7 9.7e-16 58.1 0.5 1.2 1 0 0 1 1 1 1 UreF AFG1_ATPase PF03969.11 EAU84331.2 - 8.1e-95 317.6 0.0 2.9e-91 305.9 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EAU84331.2 - 0.00018 21.5 0.1 0.23 11.4 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EAU84331.2 - 0.0018 18.4 0.1 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EAU84331.2 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAU84331.2 - 0.017 14.8 0.0 0.08 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 EAU84331.2 - 0.062 12.9 0.1 0.37 10.4 0.1 2.1 1 1 0 1 1 1 0 Bacterial dnaA protein SBDS PF01172.13 EAU84332.1 - 1.9e-15 56.4 0.1 2.3e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein FBD PF08387.5 EAU84332.1 - 0.07 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 FBD VRR_NUC PF08774.6 EAU84333.2 - 1e-18 67.2 0.0 2.5e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain ArfGap PF01412.13 EAU84335.1 - 1.7e-17 63.3 0.9 5.9e-13 48.6 1.0 2.7 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf DBR1 PF05011.8 EAU84335.1 - 0.0023 17.7 0.2 0.9 9.4 0.0 2.3 2 0 0 2 2 2 2 Lariat debranching enzyme, C-terminal domain Velvet PF11754.3 EAU84336.1 - 2.6e-35 121.8 0.0 8.3e-35 120.2 0.0 1.7 1 1 0 1 1 1 1 Velvet factor PPR_2 PF13041.1 EAU84337.1 - 3.7e-20 71.6 0.1 1.6e-06 28.0 0.0 7.5 6 2 2 8 8 8 2 PPR repeat family PPR_3 PF13812.1 EAU84337.1 - 6.6e-20 69.6 3.2 0.0042 17.2 0.0 10.3 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR PF01535.15 EAU84337.1 - 4e-18 64.0 0.0 0.035 14.0 0.0 9.7 12 0 0 12 12 12 5 PPR repeat TPR_14 PF13428.1 EAU84337.1 - 5.5e-05 23.4 5.8 2 9.2 0.0 8.5 10 1 1 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU84337.1 - 0.00031 21.0 1.0 0.12 12.6 0.1 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 EAU84337.1 - 0.0011 18.3 0.1 4.2 6.9 0.0 4.9 5 0 0 5 5 5 1 PPR repeat HMG_box_2 PF09011.5 EAU84338.2 - 1.3e-16 60.7 12.6 6.3e-08 32.8 0.8 2.4 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EAU84338.2 - 9.4e-15 54.6 15.2 2.6e-08 33.9 2.2 2.7 2 1 0 2 2 2 2 HMG (high mobility group) box GRIM-19 PF06212.7 EAU84339.2 - 2.2e-32 111.4 0.1 7e-32 109.8 0.0 1.7 2 0 0 2 2 2 1 GRIM-19 protein DUF465 PF04325.8 EAU84340.2 - 0.024 14.3 3.2 0.052 13.2 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) bZIP_1 PF00170.16 EAU84340.2 - 0.058 13.3 3.9 0.16 11.9 2.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EAU84340.2 - 0.9 9.0 3.4 1.7 8.1 2.3 1.4 1 0 0 1 1 1 0 Septum formation initiator SOR_SNZ PF01680.12 EAU84341.2 - 0.027 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 SOR/SNZ family Fer4 PF00037.22 EAU84342.1 - 2e-14 52.4 18.3 6e-09 35.1 3.7 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EAU84342.1 - 3.9e-12 46.3 11.0 6.5e-12 45.6 7.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EAU84342.1 - 2.3e-10 41.0 7.8 1.3e-05 25.8 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EAU84342.1 - 6.2e-10 38.7 5.0 0.0001 22.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EAU84342.1 - 1.1e-09 38.4 11.3 1.8e-09 37.7 7.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EAU84342.1 - 5.6e-09 35.6 11.8 1.5e-08 34.3 8.3 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EAU84342.1 - 2.8e-08 33.2 18.7 0.00028 20.6 3.8 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EAU84342.1 - 6.1e-08 32.5 18.8 2.4e-05 24.2 7.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EAU84342.1 - 8.6e-08 31.6 15.9 0.00022 20.9 2.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EAU84342.1 - 9.5e-07 28.6 11.0 0.00036 20.6 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EAU84342.1 - 1.2e-06 28.7 8.8 0.00031 21.0 7.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EAU84342.1 - 6.1e-06 26.5 8.2 0.019 15.3 0.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EAU84342.1 - 0.00078 19.7 13.0 0.097 13.0 0.9 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EAU84342.1 - 0.0017 18.8 12.9 0.21 12.1 0.9 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 EAU84342.1 - 0.024 14.7 4.3 0.092 12.8 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 EAU84342.1 - 0.13 12.8 19.0 0.28 11.8 3.8 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Prefoldin_2 PF01920.15 EAU84343.1 - 3.6e-21 74.9 0.5 4.5e-21 74.6 0.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 EAU84343.1 - 0.0078 15.8 1.2 0.013 15.1 0.5 1.5 2 0 0 2 2 2 1 DASH complex subunit Dad3 IncA PF04156.9 EAU84343.1 - 0.017 14.7 1.9 0.03 13.9 1.3 1.6 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 EAU84343.1 - 0.044 13.7 1.3 1.9 8.4 0.9 2.2 2 0 0 2 2 2 0 FlxA-like protein ATG16 PF08614.6 EAU84343.1 - 0.057 13.2 1.9 0.061 13.1 0.3 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CAP PF00188.21 EAU84344.1 - 2.3e-11 44.2 0.1 5.2e-11 43.0 0.1 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family F-box-like PF12937.2 EAU84348.1 - 2.9e-07 30.0 0.1 7e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU84348.1 - 3.7e-06 26.4 0.0 7.7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain zf-H2C2_2 PF13465.1 EAU84349.1 - 1.5e-08 34.5 17.3 1.5e-07 31.3 1.0 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EAU84349.1 - 3.1e-08 33.4 19.1 6.1e-06 26.2 0.2 4.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EAU84349.1 - 3.1e-05 23.9 0.7 0.017 15.2 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EAU84349.1 - 0.0002 21.4 18.4 0.00088 19.4 0.2 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger DUF4451 PF14616.1 EAU84349.1 - 0.0015 18.3 1.4 0.0033 17.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) zf-met PF12874.2 EAU84349.1 - 0.014 15.6 0.4 1.8 8.8 0.1 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAU84349.1 - 0.049 13.5 0.4 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EAU84349.1 - 5.1 7.5 9.6 3.9 7.8 0.2 3.6 4 0 0 4 4 4 0 C2H2-type zinc-finger domain UCH PF00443.24 EAU84350.1 - 4.2e-51 173.6 0.0 5.8e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU84350.1 - 5.7e-23 81.7 0.0 8e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EAU84350.1 - 0.0017 17.6 1.0 0.016 14.5 0.7 2.3 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase PP2C PF00481.16 EAU84351.2 - 4.2e-27 95.1 0.0 6.2e-24 84.7 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAU84351.2 - 2.4e-06 27.0 0.0 1.6e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2914 PF11141.3 EAU84351.2 - 0.62 9.6 5.8 0.8 9.2 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) ACT_7 PF13840.1 EAU84353.2 - 5.6e-12 45.0 0.0 9.4e-12 44.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain Fer2_4 PF13510.1 EAU84354.2 - 0.12 12.1 0.0 2.6 7.8 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.20 EAU84355.1 - 5.8e-32 110.9 0.3 1.4e-31 109.6 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU84355.1 - 2.6e-13 50.0 0.8 5.6e-12 45.6 0.6 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU84355.1 - 6e-09 36.0 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAU84355.1 - 0.00054 20.0 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding LVIVD PF08309.6 EAU84356.2 - 0.057 12.4 0.6 0.23 10.5 0.1 2.3 2 0 0 2 2 2 0 LVIVD repeat Trp_dioxygenase PF03301.8 EAU84356.2 - 0.17 10.9 0.1 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase DUF3635 PF12330.3 EAU84357.1 - 1.9e-17 63.1 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Sld5 PF05916.6 EAU84358.2 - 5.9e-17 61.9 0.1 8.5e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein P21-Arc PF04062.9 EAU84360.2 - 2.5e-78 261.8 0.0 2.8e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.6 EAU84361.2 - 2.5e-27 94.4 0.9 4.5e-27 93.6 0.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EAU84361.2 - 0.05 13.1 1.1 0.38 10.3 0.1 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Iso_dh PF00180.15 EAU84362.1 - 1.4e-124 415.5 0.0 1.7e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Alpha-amylase_C PF02806.13 EAU84363.1 - 5.9e-24 84.0 0.3 3.2e-23 81.6 0.1 2.3 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EAU84363.1 - 1.1e-18 67.7 0.2 1.2e-13 51.1 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EAU84363.1 - 1.4e-17 63.5 0.0 3e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF1732 PF08340.6 EAU84363.1 - 0.058 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) zf-RING_5 PF14634.1 EAU84364.2 - 1.5e-05 24.6 14.9 2.3e-05 23.9 10.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EAU84364.2 - 2.1e-05 24.2 13.6 3.3e-05 23.6 9.4 1.3 1 0 0 1 1 1 1 Ring finger domain CCDC155 PF14662.1 EAU84364.2 - 0.00086 18.9 9.1 0.00086 18.9 6.3 2.0 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 zf-C3HC4 PF00097.20 EAU84364.2 - 0.00089 18.8 14.9 0.0015 18.1 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU84364.2 - 0.006 16.5 15.2 0.0097 15.9 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DivIVA PF05103.8 EAU84364.2 - 0.0098 15.9 1.3 0.0098 15.9 0.9 3.3 3 0 0 3 3 3 1 DivIVA protein zf-RING_4 PF14570.1 EAU84364.2 - 0.21 11.1 16.0 0.41 10.2 11.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TBPIP PF07106.8 EAU84364.2 - 0.26 10.8 6.7 0.13 11.8 2.2 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rep_fac-A_C PF08646.5 EAU84364.2 - 0.26 10.9 5.2 0.63 9.7 3.6 1.6 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-Apc11 PF12861.2 EAU84364.2 - 0.32 10.8 3.8 0.58 10.0 2.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Herpes_UL6 PF01763.11 EAU84364.2 - 0.43 8.6 4.5 0.71 7.9 3.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like zf-C3HC4_4 PF15227.1 EAU84364.2 - 0.47 10.3 17.0 0.96 9.3 11.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EAU84364.2 - 0.74 9.4 12.8 4.8 6.7 8.8 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF904 PF06005.7 EAU84364.2 - 0.79 10.0 18.2 0.059 13.6 1.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Cep57_MT_bd PF06657.8 EAU84364.2 - 1.3 9.0 9.2 0.9 9.5 0.3 3.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 EAU84364.2 - 1.4 8.5 24.4 0.46 10.0 7.5 2.3 2 0 0 2 2 2 0 IncA protein zf-RING_UBOX PF13445.1 EAU84364.2 - 4.1 7.1 11.9 11 5.8 8.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger HALZ PF02183.13 EAU84364.2 - 5.3 6.8 12.1 3.6 7.3 1.5 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper RhoGEF PF00621.15 EAU84367.2 - 2.7e-23 82.7 0.7 6.5e-22 78.2 0.5 2.6 1 1 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EAU84369.2 - 2e-12 46.4 11.0 0.021 14.4 0.5 7.9 4 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAU84369.2 - 6.3e-11 41.1 16.7 0.3 11.3 0.3 8.1 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.28 EAU84369.2 - 1.7e-08 33.3 18.6 0.73 10.0 0.1 7.7 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_7 PF13504.1 EAU84369.2 - 1.6e-07 30.3 16.7 1.1 9.8 0.1 8.1 7 0 0 7 7 7 2 Leucine rich repeat LRR_8 PF13855.1 EAU84369.2 - 2.5e-06 27.1 17.8 0.0026 17.4 0.1 6.4 5 2 2 7 7 7 2 Leucine rich repeat Amidohydro_4 PF13147.1 EAU84370.1 - 1.6e-18 67.7 2.4 5e-17 62.8 0.2 3.3 3 1 0 3 3 3 1 Amidohydrolase Amidohydro_5 PF13594.1 EAU84370.1 - 7.3e-16 57.7 1.1 1e-09 38.0 0.3 2.9 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EAU84370.1 - 9.2e-07 28.8 0.1 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EAU84370.1 - 4.6e-06 26.1 3.9 0.00013 21.3 0.1 2.6 3 0 0 3 3 3 2 Amidohydrolase family HHH_2 PF12826.2 EAU84370.1 - 0.084 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Myb_DNA-binding PF00249.26 EAU84371.2 - 1.8e-19 69.5 4.5 1.9e-10 40.6 0.0 4.5 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAU84371.2 - 1.8e-18 66.3 3.4 4.1e-14 52.4 0.2 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain MbeD_MobD PF04899.7 EAU84371.2 - 0.015 15.1 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 MbeD/MobD like DUF2052 PF09747.4 EAU84372.2 - 1.1e-07 31.9 15.4 2e-07 31.0 10.7 1.3 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF676 PF05057.9 EAU84374.2 - 6.1e-08 32.2 0.0 9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EAU84374.2 - 1.5e-05 24.7 2.2 0.0001 22.0 1.3 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU84374.2 - 6.3e-05 22.9 6.9 0.00013 21.9 4.8 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EAU84374.2 - 0.004 16.7 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EAU84374.2 - 0.0053 16.3 0.4 0.027 14.0 0.2 2.0 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EAU84374.2 - 0.0062 16.1 0.6 0.014 15.0 0.0 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 EAU84374.2 - 0.013 14.8 0.0 0.048 12.9 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cyto_ox_2 PF02322.10 EAU84374.2 - 0.041 13.0 0.7 0.073 12.2 0.4 1.4 2 0 0 2 2 2 0 Cytochrome oxidase subunit II DUF915 PF06028.6 EAU84374.2 - 0.042 12.9 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EAU84374.2 - 0.055 12.3 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 EAU84374.2 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Acetyltransf_1 PF00583.19 EAU84375.1 - 1.2e-14 54.0 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAU84375.1 - 3.3e-06 26.7 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EAU84375.1 - 3.1e-05 24.0 0.0 3.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAU84375.1 - 0.00014 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU84375.1 - 0.0026 17.5 0.0 0.0042 16.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAU84375.1 - 0.0097 16.0 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU84375.1 - 0.079 12.9 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1999 PF09390.5 EAU84375.1 - 0.081 12.2 0.0 0.21 10.9 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1999) PAF-AH_p_II PF03403.8 EAU84376.2 - 4.1e-13 48.3 0.0 5.2e-08 31.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EAU84376.2 - 7.5e-05 22.7 0.0 9.9e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU84376.2 - 0.0018 18.0 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EAU84376.2 - 0.11 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) YjeF_N PF03853.10 EAU84377.2 - 2.5e-33 115.0 0.0 1.3e-25 89.9 0.0 2.1 1 1 1 2 2 2 2 YjeF-related protein N-terminus Abhydrolase_3 PF07859.8 EAU84378.2 - 5e-37 127.5 0.0 7.3e-30 104.1 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU84378.2 - 3.5e-11 42.3 0.0 8.1e-11 41.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF664 PF04978.7 EAU84378.2 - 0.00036 20.8 0.6 0.38 10.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF664) Abhydrolase_5 PF12695.2 EAU84378.2 - 0.00085 19.1 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EAU84378.2 - 0.043 12.5 0.1 0.69 8.5 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Inh PF02974.9 EAU84378.2 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh Tubulin PF00091.20 EAU84379.1 - 3.2e-67 226.5 0.0 4.4e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAU84379.1 - 3e-48 163.0 0.0 5.1e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EAU84379.1 - 0.00071 19.0 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EAU84379.1 - 0.02 14.4 0.0 0.86 9.2 0.0 2.4 2 0 0 2 2 2 0 Lipase (class 3) tRNA-synt_1c PF00749.16 EAU84380.1 - 1.7e-105 352.1 0.0 2.4e-105 351.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EAU84380.1 - 1.5e-34 118.8 0.0 2.5e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EAU84380.1 - 8.1e-31 107.0 0.0 1.8e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EAU84380.1 - 7.3e-12 45.8 3.1 7.3e-12 45.8 2.1 2.8 3 0 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 AAA PF00004.24 EAU84381.2 - 4.3e-21 75.5 0.0 1.2e-20 74.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU84381.2 - 0.0003 20.9 1.1 0.067 13.3 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EAU84381.2 - 0.031 14.2 0.3 1.1 9.2 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 EAU84381.2 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EAU84381.2 - 0.16 11.5 0.0 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain Tautomerase PF01361.16 EAU84382.2 - 0.12 12.0 0.4 0.28 10.8 0.3 1.7 1 0 0 1 1 1 0 Tautomerase enzyme DUF1949 PF09186.6 EAU84382.2 - 0.23 11.0 1.2 0.65 9.6 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) DMAP1 PF05499.7 EAU84382.2 - 3.8 7.0 8.1 1.5 8.3 0.0 3.2 4 0 0 4 4 4 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF202 PF02656.10 EAU84383.1 - 5.2e-14 52.2 1.3 5.2e-14 52.2 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TctB PF07331.6 EAU84383.1 - 0.085 12.5 3.1 0.31 10.6 0.4 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4234 PF14018.1 EAU84383.1 - 0.14 11.9 0.8 0.21 11.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2530 PF10745.4 EAU84383.1 - 4 7.4 9.2 1.1 9.2 0.2 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) zf-U1 PF06220.7 EAU84384.1 - 1.3e-20 72.5 4.1 1.9e-20 72.1 2.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EAU84384.1 - 0.014 15.5 2.3 0.025 14.7 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding LSM PF01423.17 EAU84385.1 - 8.8e-19 66.8 0.2 1.1e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF4050 PF13259.1 EAU84386.2 - 0.0029 17.5 1.5 0.0061 16.4 1.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) F-box-like PF12937.2 EAU84387.2 - 1e-10 41.1 1.1 2.2e-10 40.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU84387.2 - 1.9e-09 36.9 0.0 1.2 8.8 0.0 6.4 4 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAU84387.2 - 2.9e-08 32.9 0.2 40 4.7 0.0 9.5 12 0 0 12 12 12 0 Leucine Rich repeat LRR_8 PF13855.1 EAU84387.2 - 2e-06 27.4 10.7 0.2 11.4 0.1 5.8 5 1 1 6 6 6 2 Leucine rich repeat F-box PF00646.28 EAU84387.2 - 0.00043 19.8 0.3 0.00043 19.8 0.2 2.1 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 EAU84387.2 - 0.0014 18.4 10.1 84 3.8 0.1 8.0 8 2 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.2 EAU84388.2 - 8.5e-13 47.6 0.0 0.042 13.4 0.0 6.2 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAU84388.2 - 1.4e-08 33.9 4.7 1.1 9.5 0.0 8.7 9 0 0 9 9 9 1 Leucine Rich repeat LRR_8 PF13855.1 EAU84388.2 - 4.8e-08 32.6 7.1 0.12 12.1 0.1 5.6 4 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EAU84388.2 - 1.1e-07 30.8 5.0 6.1 7.2 0.0 8.8 7 5 1 8 8 8 1 Leucine Rich Repeat F-box-like PF12937.2 EAU84388.2 - 7.8e-06 25.5 0.3 2.2e-05 24.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like CPSF100_C PF13299.1 EAU84389.1 - 2.2e-31 109.2 0.8 1.7e-30 106.3 0.0 2.6 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EAU84389.1 - 1.6e-23 83.0 0.0 4.1e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain CDC45 PF02724.9 EAU84389.1 - 1 7.3 9.4 1.6 6.6 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein LNS2 PF08235.8 EAU84390.1 - 7.7e-71 236.7 0.0 1.2e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EAU84390.1 - 2.9e-32 110.6 0.0 8.2e-32 109.1 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EAU84390.1 - 0.13 11.6 0.2 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Complex1_LYR PF05347.10 EAU84391.1 - 1e-11 44.4 2.3 1.5e-11 43.9 1.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAU84391.1 - 5e-11 42.6 1.6 6.5e-11 42.2 1.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RRN3 PF05327.6 EAU84392.1 - 1.2e-153 512.2 0.0 1.2e-153 512.2 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EAU84392.1 - 0.45 8.3 29.0 0.032 12.1 9.4 2.2 2 0 0 2 2 2 0 Nop14-like family RRM_1 PF00076.17 EAU84394.1 - 1.2e-16 60.0 1.2 6.4e-16 57.7 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84394.1 - 9e-14 51.2 0.0 1.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU84394.1 - 2.5e-11 43.2 0.0 1.3e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU84394.1 - 0.0048 16.6 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EAU84394.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TFIID-18kDa PF02269.11 EAU84395.2 - 5.4e-21 74.2 0.1 8.4e-21 73.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit PAT1 PF09770.4 EAU84395.2 - 0.49 8.5 7.8 0.58 8.3 5.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EAU84395.2 - 0.81 9.5 4.5 0.79 9.5 3.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S10 PF00450.17 EAU84396.1 - 3e-93 313.2 0.0 3.9e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase stn_TNFRSF12A PF12191.3 EAU84396.1 - 0.024 14.6 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SAM_2 PF07647.12 EAU84396.1 - 0.036 13.9 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SKG6 PF08693.5 EAU84396.1 - 0.046 13.0 5.2 0.082 12.2 3.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EAU84396.1 - 0.088 12.4 0.1 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family GHMP_kinases_C PF08544.8 EAU84397.2 - 0.17 12.0 0.3 0.45 10.7 0.0 1.8 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1857 PF08982.6 EAU84399.2 - 1.4e-10 40.9 0.0 2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Arrestin_N PF00339.24 EAU84400.2 - 0.0029 17.4 0.0 0.031 14.0 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 EAU84400.2 - 0.12 11.4 1.3 9.5 5.1 0.0 2.2 2 0 0 2 2 2 0 Rgp1 Abhydrolase_2 PF02230.11 EAU84403.1 - 5.2e-56 189.4 0.0 1e-55 188.5 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAU84403.1 - 5.7e-13 48.8 0.0 8.5e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU84403.1 - 8.2e-10 38.9 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EAU84403.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EAU84403.1 - 0.0038 16.8 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EAU84403.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.4 EAU84403.1 - 0.026 13.7 0.0 0.24 10.6 0.0 2.0 1 1 1 2 2 2 0 Esterase PHB depolymerase DUF3700 PF12481.3 EAU84403.1 - 0.051 12.7 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Aluminium induced protein DUF2048 PF09752.4 EAU84403.1 - 0.071 11.9 0.1 2.1 7.1 0.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) tRNA_m1G_MT PF01746.16 EAU84404.2 - 1.5e-34 119.2 0.0 1.3e-26 93.3 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Amelin PF05111.7 EAU84404.2 - 0.0035 16.1 0.2 0.0049 15.6 0.1 1.1 1 0 0 1 1 1 1 Ameloblastin precursor (Amelin) DUF899 PF05988.7 EAU84404.2 - 2.9 7.2 5.5 5.4 6.3 3.8 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) DDRGK PF09756.4 EAU84404.2 - 8.2 5.7 16.2 15 4.9 11.2 1.3 1 0 0 1 1 1 0 DDRGK domain Methyltransf_23 PF13489.1 EAU84405.1 - 1.8e-11 43.9 0.0 2.7e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU84405.1 - 2.3e-08 34.4 0.0 4.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU84405.1 - 4e-06 27.2 0.0 7.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU84405.1 - 5.3e-06 26.1 0.0 7.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU84405.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAU84405.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.12 EAU84405.1 - 0.16 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family RNA_pol_Rpb2_6 PF00562.23 EAU84409.2 - 2.3e-103 345.9 0.0 3.3e-103 345.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EAU84409.2 - 8e-31 106.5 0.0 1.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EAU84409.2 - 6.9e-26 89.8 0.0 1.6e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.9 EAU84409.2 - 3.4e-23 82.0 0.0 9.2e-23 80.6 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EAU84409.2 - 3.6e-21 74.8 0.0 8.4e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EAU84409.2 - 1.8e-18 66.5 0.1 2.9e-14 53.0 0.1 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EAU84409.2 - 0.00032 20.6 0.1 0.00069 19.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 VPS9 PF02204.13 EAU84409.2 - 0.17 11.8 0.1 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 9 (VPS9) domain GDPD PF03009.12 EAU84411.1 - 1.7e-30 106.3 0.1 4e-30 105.1 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EAU84411.1 - 0.015 15.4 2.8 0.026 14.7 0.2 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.16 EAU84412.2 - 5.7e-30 103.4 0.0 9e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF737 PF05300.6 EAU84413.2 - 0.043 13.7 2.3 0.084 12.8 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Ribonuc_red_lgN PF00317.16 EAU84413.2 - 0.071 12.9 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain RRM_1 PF00076.17 EAU84414.2 - 1.2e-11 44.1 0.2 1.1e-06 28.1 0.0 4.0 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84414.2 - 0.0069 16.3 0.0 0.3 11.0 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU84414.2 - 0.07 12.9 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAS20 PF02064.10 EAU84415.2 - 2.6e-19 69.3 0.1 1e-18 67.3 0.1 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 EAU84415.2 - 8.9e-05 22.8 0.0 0.0005 20.4 0.0 2.2 2 0 0 2 2 2 1 SET domain SAF PF08666.7 EAU84415.2 - 0.046 14.1 0.2 7.4 7.0 0.0 2.9 2 0 0 2 2 2 0 SAF domain SMK-1 PF04802.10 EAU84416.2 - 1.7e-49 167.9 7.0 1.6e-47 161.5 4.8 3.1 1 1 0 1 1 1 1 Component of IIS longevity pathway SMK-1 CLPTM1 PF05602.7 EAU84419.2 - 2.3e-144 481.4 0.0 2.9e-144 481.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EAU84419.2 - 0.00071 19.0 0.4 0.0044 16.5 0.1 2.3 2 0 0 2 2 2 1 PQ loop repeat 2TM PF13239.1 EAU84419.2 - 1.4 9.0 9.5 0.37 10.8 1.2 2.9 2 1 1 3 3 3 0 2TM domain Tropomyosin_1 PF12718.2 EAU84420.1 - 0.0044 16.8 1.6 0.0065 16.3 1.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EAU84420.1 - 0.017 14.1 5.5 0.024 13.7 3.8 1.0 1 0 0 1 1 1 0 Tropomyosin TSC22 PF01166.13 EAU84421.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family 14-3-3 PF00244.15 EAU84422.1 - 3.5e-118 392.8 4.4 4e-118 392.6 3.1 1.0 1 0 0 1 1 1 1 14-3-3 protein HisKA PF00512.20 EAU84422.1 - 0.037 14.0 0.9 2.4 8.2 0.1 2.8 2 1 0 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF837 PF05769.6 EAU84422.1 - 0.053 13.0 4.0 1.1 8.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_19 PF14559.1 EAU84422.1 - 0.32 11.3 2.0 2.4 8.5 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PLU-1 PF08429.6 EAU84425.2 - 1.1e-54 185.6 7.4 5.1e-54 183.4 5.0 2.2 1 1 1 2 2 2 1 PLU-1-like protein JmjC PF02373.17 EAU84425.2 - 2.2e-41 140.6 0.3 5e-41 139.5 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EAU84425.2 - 1.7e-20 72.6 0.0 5.2e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EAU84425.2 - 3.3e-15 55.2 0.4 3.3e-15 55.2 0.3 2.0 2 0 0 2 2 2 1 jmjN domain zf-C5HC2 PF02928.11 EAU84425.2 - 1.5e-12 47.3 10.2 6e-12 45.4 7.1 2.2 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EAU84425.2 - 5.3e-07 29.2 32.9 0.0017 18.0 0.2 4.7 4 0 0 4 4 4 3 PHD-finger DUF3416 PF11896.3 EAU84425.2 - 0.38 10.6 2.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) CorA PF01544.13 EAU84426.1 - 1.2e-42 145.9 0.3 1.9e-42 145.2 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein A_thal_3526 PF09713.5 EAU84426.1 - 0.026 14.6 0.1 0.051 13.7 0.1 1.5 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Baculo_PEP_C PF04513.7 EAU84426.1 - 0.028 14.2 0.3 0.063 13.1 0.2 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 EAU84426.1 - 0.19 11.4 0.3 1.9 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) F-box-like PF12937.2 EAU84427.2 - 1.5e-08 34.1 1.5 1.5e-08 34.1 1.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 EAU84427.2 - 0.019 15.0 3.0 14 6.4 0.0 5.4 5 1 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 EAU84427.2 - 0.29 10.8 10.5 0.63 9.7 2.4 3.4 2 1 0 2 2 2 0 F-box domain Uds1 PF15456.1 EAU84429.1 - 3e-35 120.9 11.8 3e-35 120.9 8.2 6.5 3 2 3 6 6 6 1 Up-regulated During Septation Spc7 PF08317.6 EAU84429.1 - 0.0017 17.0 20.0 0.0017 17.0 13.9 4.7 3 2 1 4 4 4 2 Spc7 kinetochore protein HR1 PF02185.11 EAU84429.1 - 0.0078 15.9 3.6 0.0078 15.9 2.5 8.2 6 2 0 6 6 6 1 Hr1 repeat DUF3584 PF12128.3 EAU84429.1 - 8.8 3.5 95.6 0.22 8.7 14.1 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) ORMDL PF04061.9 EAU84431.2 - 2.4e-45 153.4 1.1 5e-44 149.1 0.8 2.3 1 1 0 1 1 1 1 ORMDL family PIG-P PF08510.7 EAU84431.2 - 0.3 10.7 1.8 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 PIG-P THF_DHG_CYH PF00763.18 EAU84432.1 - 7.4e-18 64.6 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EAU84432.1 - 1.8e-16 59.6 0.1 2e-08 33.5 0.0 2.8 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EAU84432.1 - 0.0019 18.3 0.1 0.23 11.5 0.0 2.4 1 1 1 2 2 2 2 Shikimate / quinate 5-dehydrogenase IPP-2 PF04979.9 EAU84433.1 - 3.3e-13 50.0 1.6 6.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Sporozoite_P67 PF05642.6 EAU84434.1 - 1.3 6.7 8.0 2 6.1 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 EAU84434.1 - 9 4.1 7.2 11 3.9 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3246 PF11596.3 EAU84435.1 - 2.2 7.4 5.0 0.51 9.5 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) AAA PF00004.24 EAU84436.2 - 1.7e-48 164.1 0.0 2.1e-32 112.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU84436.2 - 4.2e-09 36.6 1.2 0.00044 20.3 0.1 4.0 2 2 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EAU84436.2 - 3.1e-08 34.4 0.1 0.00052 20.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EAU84436.2 - 3.5e-07 30.5 0.1 0.0014 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EAU84436.2 - 9.9e-07 28.7 0.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EAU84436.2 - 1.6e-06 27.8 0.1 0.0023 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EAU84436.2 - 1.9e-06 26.8 0.1 0.022 13.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 EAU84436.2 - 2.7e-06 27.4 0.2 0.025 14.5 0.0 3.0 3 1 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.1 EAU84436.2 - 4.3e-06 26.6 0.0 0.023 14.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EAU84436.2 - 5.8e-06 25.5 0.2 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus CDC48_2 PF02933.12 EAU84436.2 - 9.1e-06 25.2 0.1 0.00018 21.0 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 EAU84436.2 - 1e-05 25.1 1.4 0.0057 16.3 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 EAU84436.2 - 1.2e-05 25.3 0.0 0.00097 19.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EAU84436.2 - 1.4e-05 25.2 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 EAU84436.2 - 1.8e-05 23.9 0.0 0.058 12.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 EAU84436.2 - 2.9e-05 23.6 0.3 0.1 12.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EAU84436.2 - 4.3e-05 22.7 0.4 0.014 14.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EAU84436.2 - 5.5e-05 22.3 0.0 0.049 12.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) CDC48_N PF02359.13 EAU84436.2 - 8.5e-05 22.4 0.0 0.00038 20.3 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain IstB_IS21 PF01695.12 EAU84436.2 - 9.7e-05 21.8 0.9 0.04 13.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 EAU84436.2 - 0.00021 21.2 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EAU84436.2 - 0.00022 20.8 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAU84436.2 - 0.00046 19.6 6.6 3.6 6.9 0.4 4.2 2 2 1 4 4 4 1 AAA domain AAA_24 PF13479.1 EAU84436.2 - 0.00097 18.7 2.8 0.2 11.1 0.5 2.7 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EAU84436.2 - 0.0013 19.0 0.3 0.083 13.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EAU84436.2 - 0.0014 18.1 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EAU84436.2 - 0.0019 17.8 1.3 1.5 8.4 0.0 3.1 4 0 0 4 4 3 1 NACHT domain SKI PF01202.17 EAU84436.2 - 0.0036 17.2 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase AAA_30 PF13604.1 EAU84436.2 - 0.005 16.4 0.0 0.58 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EAU84436.2 - 0.0081 15.2 6.9 0.2 10.7 0.2 3.8 3 1 1 4 4 4 1 KaiC CPT PF07931.7 EAU84436.2 - 0.01 15.4 0.1 0.92 9.1 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 EAU84436.2 - 0.014 14.3 0.4 0.73 8.6 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_11 PF13086.1 EAU84436.2 - 0.016 14.7 0.0 0.74 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EAU84436.2 - 0.021 13.7 0.1 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KTI12 PF08433.5 EAU84436.2 - 0.047 12.8 0.0 0.54 9.4 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 PhoH PF02562.11 EAU84436.2 - 0.065 12.4 0.2 0.73 9.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein KAP_NTPase PF07693.9 EAU84436.2 - 0.1 11.5 0.2 4.8 6.0 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain ResIII PF04851.10 EAU84436.2 - 0.12 12.2 0.2 4.8 6.9 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 EAU84436.2 - 0.13 10.8 0.2 3.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 EAU84436.2 - 0.14 11.6 0.9 2.6 7.4 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DUF3661 PF12400.3 EAU84437.1 - 6.3e-38 129.7 1.9 9.2e-38 129.2 1.3 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DUF2009 PF09418.5 EAU84438.1 - 7e-207 687.7 0.0 8.1e-207 687.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EAU84438.1 - 2.5e-07 30.4 4.0 4.5e-07 29.6 2.7 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-C3HC4_3 PF13920.1 EAU84438.1 - 0.33 10.6 3.5 0.61 9.7 2.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pro-kuma_activ PF09286.6 EAU84439.1 - 1.1e-38 132.5 0.1 1.7e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EAU84439.1 - 1.6e-08 34.0 0.0 2.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family PCI PF01399.22 EAU84440.1 - 3.1e-12 46.7 0.1 3.4e-11 43.4 0.0 2.4 2 1 0 2 2 2 1 PCI domain Hep_59 PF07052.6 EAU84441.2 - 9.7e-27 93.3 1.7 9.7e-27 93.3 1.2 2.1 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DLIC PF05783.6 EAU84443.2 - 4e-39 134.5 0.2 1.3e-34 119.6 0.0 3.0 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 EAU84443.2 - 0.0082 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EAU84443.2 - 0.017 15.4 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EAU84443.2 - 0.032 14.0 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Dynamin family KTI12 PF08433.5 EAU84443.2 - 0.05 12.8 0.0 0.08 12.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Miro PF08477.8 EAU84443.2 - 0.059 13.8 0.0 0.75 10.3 0.0 2.5 2 1 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EAU84443.2 - 0.08 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU84443.2 - 0.11 12.4 0.0 0.74 9.7 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 EAU84443.2 - 0.12 13.2 0.0 0.29 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain TIP41 PF04176.8 EAU84444.2 - 1.5e-48 164.4 0.0 1.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family TFIID_20kDa PF03847.8 EAU84445.1 - 1.5e-28 98.8 0.2 2.5e-28 98.1 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EAU84445.1 - 0.00023 21.1 0.0 0.00075 19.5 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PDZ_2 PF13180.1 EAU84445.1 - 0.027 14.3 0.1 0.13 12.1 0.0 2.1 1 1 1 2 2 2 0 PDZ domain RRS1 PF04939.7 EAU84446.2 - 2.1e-57 193.1 5.7 2.1e-57 193.1 3.9 1.8 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) GH3 PF03321.8 EAU84446.2 - 0.002 16.7 0.5 0.0029 16.2 0.4 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Protocadherin PF08374.6 EAU84446.2 - 0.022 14.4 1.1 0.022 14.4 0.8 1.6 1 1 0 1 1 1 0 Protocadherin FAD_binding_4 PF01565.18 EAU84447.2 - 1.2e-26 92.8 2.4 1.8e-26 92.2 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU84447.2 - 3.6e-05 23.5 0.0 0.00015 21.6 0.0 2.1 1 0 0 1 1 1 1 Berberine and berberine like Btz PF09405.5 EAU84449.1 - 4e-11 43.0 5.7 4e-11 43.0 3.9 2.8 4 1 0 4 4 4 1 CASC3/Barentsz eIF4AIII binding Pox_Ag35 PF03286.9 EAU84450.2 - 0.055 12.9 0.9 0.097 12.1 0.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4613 PF15390.1 EAU84450.2 - 0.33 9.0 1.5 0.51 8.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Phos_pyr_kin PF08543.7 EAU84451.1 - 2.2e-83 279.2 2.0 4.4e-81 271.7 1.4 2.2 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EAU84451.1 - 5.4e-44 150.4 0.0 8.1e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EAU84451.1 - 7.7e-06 25.2 0.7 0.00032 19.9 0.5 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EAU84451.1 - 0.066 12.4 5.8 0.061 12.5 1.0 2.4 2 1 0 2 2 2 0 Carbohydrate kinase UPF0029 PF01205.14 EAU84452.2 - 1.1e-28 99.0 0.0 2.1e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EAU84452.2 - 7.3e-06 25.8 0.1 2.4e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 RWD domain Peptidase_U57 PF05582.7 EAU84452.2 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Aldedh PF00171.17 EAU84453.2 - 1.6e-159 531.1 1.8 1.8e-159 530.9 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAA_hydrolase PF01557.13 EAU84454.1 - 3.8e-56 189.9 0.0 4.6e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Coiled-coil_56 PF09813.4 EAU84457.1 - 1.1e-07 31.7 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 TOMM6 PF15184.1 EAU84457.1 - 0.027 13.7 0.8 0.045 13.0 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit TOM6 homolog HSP9_HSP12 PF04119.7 EAU84457.1 - 0.035 14.1 2.1 0.054 13.5 1.5 1.3 1 0 0 1 1 1 0 Heat shock protein 9/12 DUF1556 PF07590.6 EAU84458.2 - 1.3 9.2 3.5 0.81 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Spc97_Spc98 PF04130.8 EAU84459.2 - 2.8e-67 227.2 0.1 4e-67 226.7 0.1 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family FAM110_C PF14160.1 EAU84460.2 - 0.11 13.4 0.4 1.7 9.6 0.1 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus RRM_1 PF00076.17 EAU84461.2 - 5e-20 70.9 0.0 9.6e-20 70.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84461.2 - 7.1e-12 45.1 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU84461.2 - 2.2e-09 36.9 0.0 4.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.7 EAU84461.2 - 0.0089 15.3 13.1 0.012 14.9 9.1 1.1 1 0 0 1 1 1 1 SDA1 PcfK PF14058.1 EAU84461.2 - 0.021 14.9 10.3 0.041 14.0 7.1 1.4 1 0 0 1 1 1 0 PcfK-like protein Nup35_RRM_2 PF14605.1 EAU84461.2 - 0.023 14.4 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Herpes_DNAp_acc PF04929.7 EAU84461.2 - 0.089 11.7 7.7 0.12 11.3 5.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDRGK PF09756.4 EAU84461.2 - 0.15 11.4 12.3 0.28 10.5 8.5 1.3 1 0 0 1 1 1 0 DDRGK domain eIF-3c_N PF05470.7 EAU84461.2 - 0.72 7.8 9.0 0.9 7.5 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus UPF0560 PF10577.4 EAU84461.2 - 0.75 7.9 8.0 0.98 7.5 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RR_TM4-6 PF06459.7 EAU84461.2 - 1.4 8.7 9.5 2.3 8.0 6.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 EAU84461.2 - 4.9 6.2 13.1 6.4 5.8 9.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF3464 PF11947.3 EAU84461.2 - 7.9 5.9 7.2 17 4.8 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) YqfQ PF14181.1 EAU84461.2 - 9.3 6.2 9.9 18 5.3 6.9 1.5 1 0 0 1 1 1 0 YqfQ-like protein eIF-3_zeta PF05091.7 EAU84462.2 - 7.9e-185 615.3 0.0 9.9e-185 615.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Caprin-1_C PF12287.3 EAU84462.2 - 5.7 6.2 10.6 11 5.2 7.4 1.4 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DER1 PF04511.10 EAU84463.2 - 4.6e-08 32.8 4.2 6.5e-08 32.3 2.9 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 EAU84463.2 - 7.3e-07 29.3 7.7 1.2e-06 28.5 5.3 1.4 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.11 EAU84463.2 - 4.7e-06 25.9 0.0 7.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF1751 PF08551.5 EAU84463.2 - 0.0013 19.0 0.4 0.0026 18.0 0.3 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) ING PF12998.2 EAU84464.2 - 1.9e-10 40.9 0.1 7.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EAU84464.2 - 1.1e-09 37.8 9.4 1.8e-09 37.1 6.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EAU84464.2 - 0.0066 16.5 1.3 0.012 15.7 0.9 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EAU84464.2 - 0.0095 15.9 0.3 0.018 15.0 0.2 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD_2 PF13831.1 EAU84464.2 - 0.22 10.8 3.4 0.43 9.9 2.3 1.5 1 0 0 1 1 1 0 PHD-finger GATA PF00320.22 EAU84465.1 - 5.4e-09 35.2 4.3 1.1e-08 34.2 2.9 1.6 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 EAU84465.1 - 0.072 12.8 0.1 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Mucin PF01456.12 EAU84466.1 - 0.89 9.3 7.7 1.6 8.4 5.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein VCBS PF13517.1 EAU84467.2 - 0.1 13.0 0.5 1.5 9.2 0.1 2.8 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Pkinase PF00069.20 EAU84471.2 - 9.3e-31 106.9 0.0 1.4e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84471.2 - 3.7e-15 55.6 0.3 6.2e-14 51.6 0.2 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Asp_protease_2 PF13650.1 EAU84488.2 - 3.3e-07 30.7 0.0 8.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EAU84488.2 - 1.7e-06 28.0 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 EAU84488.2 - 0.0089 15.9 0.8 0.0089 15.9 0.5 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EAU84488.2 - 0.047 13.3 3.0 0.13 11.9 2.1 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF2433 PF10360.4 EAU84492.2 - 7.8e-33 113.5 0.0 1.6e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 EAU84492.2 - 1.4e-05 24.9 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU84492.2 - 0.003 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 EAU84492.2 - 0.019 14.8 0.0 0.044 13.6 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Med13_C PF06333.7 EAU84493.2 - 6.8e-25 87.4 0.5 6.8e-25 87.4 0.4 2.7 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal HSA PF07529.8 EAU84493.2 - 0.31 10.8 0.5 0.58 9.9 0.4 1.3 1 0 0 1 1 1 0 HSA ATP-synt_S1 PF05827.7 EAU84494.1 - 2.2e-11 43.5 0.9 2.2e-07 30.4 0.0 2.0 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF3651 PF12371.3 EAU84494.1 - 0.056 13.4 0.1 0.27 11.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3651) Acyl-CoA_dh_1 PF00441.19 EAU84495.1 - 1.4e-44 151.8 3.7 2e-44 151.3 2.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EAU84495.1 - 5.4e-27 94.6 0.4 2.4e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAU84495.1 - 3.1e-21 76.0 1.1 5.9e-21 75.1 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAU84495.1 - 2.2e-19 68.6 0.0 5e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EAU84495.1 - 0.033 14.4 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal adh_short PF00106.20 EAU84496.1 - 2.8e-25 89.1 0.2 3.7e-25 88.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU84496.1 - 3.6e-22 79.3 0.0 4.3e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU84496.1 - 4.6e-06 26.4 0.1 8.3e-06 25.5 0.0 1.4 2 0 0 2 2 2 1 KR domain DUF962 PF06127.6 EAU84497.1 - 4.9e-23 80.8 2.3 2.2e-22 78.7 1.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) YukC PF10140.4 EAU84497.1 - 0.095 11.2 0.4 0.15 10.6 0.3 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Longin PF13774.1 EAU84498.1 - 1.1e-28 98.6 0.1 1.6e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EAU84498.1 - 5.3e-15 54.7 0.0 8.8e-15 54.0 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF4646 PF15496.1 EAU84499.1 - 3.6e-22 78.6 0.1 1.3e-20 73.6 0.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) CAF-1_p150 PF11600.3 EAU84499.1 - 1.5 8.1 15.8 0.022 14.1 1.2 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal XRN_N PF03159.13 EAU84500.2 - 5.8e-96 320.4 0.0 5.8e-96 320.4 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EAU84500.2 - 6.3e-05 22.6 1.5 0.00015 21.5 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EAU84500.2 - 0.014 15.1 1.0 0.027 14.1 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle IF-2B PF01008.12 EAU84501.1 - 5.5e-81 271.6 0.0 6.7e-81 271.3 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Acyl-thio_N PF12590.3 EAU84501.1 - 0.27 11.7 2.4 45 4.5 2.1 2.3 2 0 0 2 2 2 0 Acyl-ATP thioesterase YihI PF04220.7 EAU84501.1 - 2.9 7.1 8.4 4.8 6.4 5.9 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) MTP18 PF10558.4 EAU84502.1 - 2.5e-57 192.9 0.3 3e-57 192.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Bac_luciferase PF00296.15 EAU84502.1 - 0.011 14.8 0.2 0.016 14.3 0.1 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Fork_head PF00250.13 EAU84503.1 - 1.4e-23 82.7 0.0 3.3e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EAU84503.1 - 4.5e-05 23.4 0.0 9.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain IPK PF03770.11 EAU84505.1 - 2.2e-51 174.3 0.0 3.3e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF4027 PF13219.1 EAU84511.2 - 0.2 11.0 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) Cactin_mid PF10312.4 EAU84512.1 - 5.1e-60 202.0 7.6 5.1e-60 202.0 5.3 2.3 2 1 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EAU84512.1 - 6e-58 193.8 6.5 1.1e-57 193.0 4.5 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein AAA_2 PF07724.9 EAU84513.2 - 5.2e-36 124.1 0.0 9.2e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EAU84513.2 - 1.5e-10 41.3 0.0 3.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EAU84513.2 - 1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Ran_BP1 PF00638.13 EAU84514.2 - 5.1e-50 168.6 0.4 9.7e-50 167.7 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain DUF1681 PF07933.9 EAU84514.2 - 1e-06 28.4 3.5 1.7e-06 27.7 2.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) WH1 PF00568.18 EAU84514.2 - 6.6e-06 25.8 0.2 4.1e-05 23.2 0.2 1.9 1 1 0 1 1 1 1 WH1 domain DUF3466 PF11949.3 EAU84514.2 - 0.0052 15.4 1.4 0.0057 15.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3466) VID27 PF08553.5 EAU84514.2 - 0.093 10.9 10.0 0.12 10.6 6.9 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein GAGA_bind PF06217.7 EAU84514.2 - 1.2 9.0 8.7 1.3 8.9 6.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family GOLD_2 PF13897.1 EAU84514.2 - 3 8.0 9.0 19 5.4 3.6 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.19 EAU84515.2 - 1.1e-49 168.6 0.0 1.3e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 EAU84515.2 - 0.034 14.5 0.0 0.094 13.1 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Kinesin PF00225.18 EAU84516.2 - 5.6e-86 288.2 0.3 4.1e-73 245.9 0.1 2.2 1 1 1 2 2 2 2 Kinesin motor domain DUF904 PF06005.7 EAU84516.2 - 1.4 9.3 6.1 2.7 8.3 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EAU84516.2 - 4 7.8 6.9 1.4 9.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Amidohydro_2 PF04909.9 EAU84517.1 - 9.3e-09 35.2 0.2 2.8e-08 33.6 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EAU84517.1 - 3.2e-08 33.9 0.2 4.1e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_6 PF00970.19 EAU84518.2 - 3.2e-11 43.2 0.0 6.2e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EAU84518.2 - 1.3e-05 25.7 0.0 1.9e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EAU84518.2 - 0.00014 21.7 0.0 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EAU84518.2 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain zf-H2C2_2 PF13465.1 EAU84519.2 - 8.9e-07 28.8 12.6 0.0044 17.2 1.3 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EAU84519.2 - 0.00042 20.4 0.6 0.00042 20.4 0.4 3.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU84519.2 - 0.012 15.9 0.5 0.012 15.9 0.3 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger DUF4366 PF14283.1 EAU84522.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Med18 PF09637.5 EAU84523.1 - 1.5e-08 34.4 0.0 3.7e-07 29.9 0.0 2.0 1 1 1 2 2 2 2 Med18 protein Toxin_51 PF15531.1 EAU84523.1 - 0.13 12.0 0.0 0.76 9.5 0.0 2.0 2 0 0 2 2 2 0 Putative toxin 51 Cyclin PF08613.6 EAU84529.1 - 1.5e-08 35.1 0.0 2.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.3 EAU84530.1 - 1.4e-128 429.4 0.0 2.3e-128 428.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EAU84530.1 - 6.2e-51 172.9 0.0 1.1e-50 172.2 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein Fork_head PF00250.13 EAU84531.2 - 6.1e-30 103.1 0.1 1.1e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Fork head domain CIAPIN1 PF05093.8 EAU84532.1 - 2.2e-30 104.6 4.2 4.4e-30 103.7 2.9 1.5 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1998 PF09369.5 EAU84532.1 - 0.0053 17.2 4.2 0.015 15.8 2.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1998) zf-HIT PF04438.11 EAU84533.2 - 1.3e-05 24.7 12.1 2e-05 24.1 8.4 1.3 1 0 0 1 1 1 1 HIT zinc finger Arf PF00025.16 EAU84534.1 - 4e-72 241.1 0.0 4.6e-72 240.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAU84534.1 - 2.4e-15 56.1 0.0 3.3e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EAU84534.1 - 3.1e-14 52.4 0.4 1.4e-09 37.2 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EAU84534.1 - 7.3e-11 41.6 0.0 8.9e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EAU84534.1 - 1.4e-10 40.8 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU84534.1 - 9.2e-09 35.8 0.0 1.2e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAU84534.1 - 2.5e-05 24.2 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU84534.1 - 0.047 13.1 0.0 0.27 10.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 EAU84535.2 - 2.9e-28 96.6 12.0 7.5e-10 38.3 0.5 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAU84535.2 - 0.0084 14.8 0.4 0.35 9.5 0.0 2.9 1 1 2 3 3 3 1 Nup133 N terminal like eIF2A PF08662.6 EAU84535.2 - 0.021 14.5 0.0 0.068 12.8 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF1481 PF07356.7 EAU84535.2 - 0.079 12.4 1.4 0.35 10.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1481) Iso_dh PF00180.15 EAU84536.1 - 1e-97 327.2 0.0 1.2e-97 327.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2373 PF10180.4 EAU84538.2 - 1.1e-19 69.7 0.2 1.1e-19 69.7 0.1 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Aminotran_1_2 PF00155.16 EAU84539.1 - 2.8e-74 250.2 0.0 3.8e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EAU84539.1 - 6.1e-05 21.4 0.0 0.00014 20.2 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EAU84539.1 - 6.6e-05 21.8 0.5 0.00028 19.7 0.0 2.1 2 1 0 3 3 3 1 Aminotransferase class-V Methyltransf_31 PF13847.1 EAU84539.1 - 0.15 11.6 0.0 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain RTC4 PF14474.1 EAU84543.2 - 2.1e-05 24.4 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Dicty_REP PF05086.7 EAU84543.2 - 5.1 4.7 10.7 8.4 4.0 7.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 2OG-FeII_Oxy_3 PF13640.1 EAU84544.1 - 3.2e-10 40.4 0.1 1.1e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAU84544.1 - 0.002 18.4 0.0 0.0051 17.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EAU84546.1 - 3.2e-08 33.9 0.0 6.4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAU84546.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.2 EAU84547.2 - 8.5e-33 114.1 0.8 1.1e-32 113.7 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU84547.2 - 8.1e-18 64.8 0.0 1.5e-16 60.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU84547.2 - 1.2e-14 54.3 0.1 4.5e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EAU84547.2 - 0.00024 20.6 0.1 0.0007 19.0 0.0 1.8 2 1 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.8 EAU84547.2 - 0.00026 20.6 0.0 0.0036 16.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 EAU84547.2 - 0.0022 16.5 0.0 0.0039 15.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 EAU84547.2 - 0.0023 17.4 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EAU84547.2 - 0.004 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 EAU84547.2 - 0.0054 16.1 0.0 1.5 8.1 0.0 3.3 4 0 0 4 4 4 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EAU84547.2 - 0.017 14.3 0.0 4.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EAU84547.2 - 0.036 13.9 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase BAAT_C PF08840.6 EAU84547.2 - 0.041 13.5 0.0 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 EAU84547.2 - 0.095 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein cwf21 PF08312.7 EAU84548.2 - 2.2e-15 56.2 11.1 2.2e-15 56.2 7.7 2.8 2 1 1 3 3 3 1 cwf21 domain 2OG-FeII_Oxy_3 PF13640.1 EAU84549.2 - 7.4e-08 32.8 0.0 3.4e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAU84549.2 - 0.014 15.6 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EAU84550.1 - 0.00019 21.3 0.0 0.00063 19.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU84550.1 - 0.094 12.4 0.0 0.24 11.1 0.0 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2089 PF09862.4 EAU84551.2 - 0.01 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Zn_clus PF00172.13 EAU84551.2 - 0.18 11.7 10.7 1.3 9.0 0.5 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF788 PF05620.6 EAU84553.1 - 9.8e-44 149.1 0.0 1.1e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Myb_DNA-bind_6 PF13921.1 EAU84554.2 - 9.2e-38 128.1 0.1 9.9e-10 38.3 0.0 5.3 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAU84554.2 - 7e-35 118.8 7.4 2.7e-12 46.5 0.1 5.2 5 0 0 5 5 5 4 Myb-like DNA-binding domain Rap1_C PF11626.3 EAU84554.2 - 3.6e-05 23.5 1.5 0.17 11.7 0.1 3.2 1 1 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MEDS PF14417.1 EAU84554.2 - 0.0039 16.2 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Myb_DNA-bind_4 PF13837.1 EAU84554.2 - 0.007 16.4 10.9 7.7 6.7 0.0 5.3 3 2 0 3 3 3 2 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EAU84554.2 - 0.2 11.8 2.1 41 4.4 0.0 3.9 3 2 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TAF8_C PF10406.4 EAU84555.2 - 2.5e-08 33.8 3.3 6.3e-08 32.5 2.3 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EAU84555.2 - 3.4e-06 26.6 0.0 5.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Flavokinase PF01687.12 EAU84556.2 - 1.2e-34 118.8 0.0 1.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.14 EAU84557.2 - 4.9e-11 42.7 0.3 1.3e-10 41.4 0.2 1.7 1 1 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L44 PF00935.14 EAU84557.2 - 0.025 14.5 0.1 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L44 UCR_UQCRX_QCR9 PF05365.7 EAU84558.1 - 3.5e-27 93.7 5.0 3.8e-27 93.6 3.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.1 EAU84558.1 - 0.0045 16.4 0.0 0.0045 16.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Patched PF02460.13 EAU84560.2 - 6.2e-68 229.4 0.7 4.3e-36 124.1 0.0 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.3 EAU84560.2 - 4.4e-46 156.1 12.8 3.6e-25 88.1 0.1 3.6 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EAU84560.2 - 5.1e-07 27.5 4.0 1.3e-06 26.1 1.1 2.0 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family MMPL PF03176.10 EAU84560.2 - 2.1 6.9 23.2 0.03 13.0 0.6 4.0 4 0 0 4 4 4 0 MMPL family Diphthamide_syn PF01866.12 EAU84561.2 - 1.3e-88 297.2 0.0 2.3e-53 181.4 0.0 2.7 2 1 0 2 2 2 2 Putative diphthamide synthesis protein Pkinase PF00069.20 EAU84562.1 - 1.8e-67 227.2 0.0 2.5e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84562.1 - 4.5e-29 101.3 0.0 6.3e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EAU84562.1 - 9.1e-15 54.9 3.2 9.3e-14 51.6 2.2 2.7 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EAU84562.1 - 7.5e-08 31.6 0.0 6.2e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EAU84562.1 - 3.6e-05 23.5 0.1 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 C2 domain APH PF01636.18 EAU84562.1 - 0.0026 17.5 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU84562.1 - 0.0064 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EAU84562.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Suc_Fer-like PF06999.7 EAU84563.2 - 3.2e-39 135.2 0.0 6e-39 134.4 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like SIR2 PF02146.12 EAU84564.2 - 1.5e-33 115.9 0.0 8.4e-33 113.5 0.0 2.2 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EAU84564.2 - 0.00093 18.9 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain zinc_ribbon_5 PF13719.1 EAU84564.2 - 0.27 10.8 1.7 3.4 7.3 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain MRP-S26 PF14943.1 EAU84565.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Acyl-CoA_dh_1 PF00441.19 EAU84567.2 - 6.8e-29 100.9 0.7 9.7e-29 100.4 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAU84567.2 - 2.3e-16 59.0 0.2 7.5e-16 57.3 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EAU84567.2 - 1.3e-11 44.8 0.7 2.2e-11 44.1 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EAU84567.2 - 6.8e-11 42.7 0.0 2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Fungal_trans PF04082.13 EAU84568.2 - 3.1e-35 121.3 0.0 4.6e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU84568.2 - 6.5e-09 35.5 10.8 1.3e-08 34.6 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMD PF08397.6 EAU84570.2 - 4.6e-07 29.3 1.2 6.9e-07 28.7 0.8 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain BAR PF03114.13 EAU84570.2 - 0.0029 17.1 1.4 0.0059 16.1 0.9 1.5 1 1 0 1 1 1 1 BAR domain End3 PF12761.2 EAU84570.2 - 0.013 15.1 1.2 0.013 15.1 0.8 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Serglycin PF04360.7 EAU84570.2 - 0.15 11.7 1.8 0.4 10.3 1.2 1.7 1 0 0 1 1 1 0 Serglycin DUF948 PF06103.6 EAU84570.2 - 8 6.4 5.7 1.6 8.6 0.3 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) tRNA-synt_2 PF00152.15 EAU84571.2 - 6.7e-97 324.2 0.0 8.4e-49 166.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAU84571.2 - 1.6e-05 24.6 0.0 4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EAU84571.2 - 0.00081 19.0 0.0 0.083 12.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) F-box-like PF12937.2 EAU84572.1 - 2.9e-05 23.7 0.5 6.4e-05 22.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like RNA_pol_Rpc34 PF05158.7 EAU84573.2 - 7.7e-73 245.5 0.3 8e-62 209.2 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EAU84573.2 - 0.074 12.9 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RPA_C PF08784.6 EAU84573.2 - 0.4 11.1 0.1 0.4 11.1 0.0 2.4 2 1 0 2 2 2 0 Replication protein A C terminal ACPS PF01648.15 EAU84574.2 - 6.3e-11 42.1 0.0 1.9e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily PfkB PF00294.19 EAU84575.2 - 0.0016 17.6 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CBFD_NFYB_HMF PF00808.18 EAU84576.2 - 2.6e-19 69.0 1.0 4.6e-19 68.2 0.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Terpene_synth PF01397.16 EAU84576.2 - 0.0025 17.1 0.7 0.0037 16.6 0.5 1.3 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Histone PF00125.19 EAU84576.2 - 0.01 15.9 0.1 0.022 14.8 0.1 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EAU84576.2 - 0.087 12.6 0.4 0.17 11.7 0.2 1.6 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit 4HB_MCP_1 PF12729.2 EAU84576.2 - 0.65 9.3 5.3 0.73 9.1 3.1 1.5 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction LSM PF01423.17 EAU84577.2 - 1.2e-20 72.7 0.0 1.4e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAU84577.2 - 0.0025 17.7 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2423 PF10338.4 EAU84578.1 - 5.1e-14 51.9 6.2 6.9e-14 51.5 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Matrilin_ccoil PF10393.4 EAU84578.1 - 0.086 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin BOP1NT PF08145.7 EAU84580.2 - 1.4e-95 319.9 8.7 2.7e-95 319.0 6.1 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EAU84580.2 - 1.7e-23 81.5 11.4 2.3e-07 30.4 0.0 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat DUF1939 PF09154.5 EAU84580.2 - 0.015 15.2 0.2 0.13 12.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) SDA1 PF05285.7 EAU84580.2 - 0.1 11.8 16.0 0.15 11.3 11.1 1.3 1 0 0 1 1 1 0 SDA1 SAPS PF04499.10 EAU84580.2 - 1.3 7.5 6.2 2.1 6.9 4.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Actin PF00022.14 EAU84581.1 - 1.3e-112 376.0 0.0 1.5e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAU84581.1 - 4.1e-08 32.2 0.0 0.0017 17.0 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein TraI PF07057.6 EAU84581.1 - 0.022 14.7 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 DNA helicase TraI Sedlin_N PF04628.8 EAU84583.2 - 4.8e-16 58.8 0.0 6.3e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rhomboid PF01694.17 EAU84584.2 - 4.5e-27 94.8 4.0 7.6e-27 94.1 2.7 1.4 1 0 0 1 1 1 1 Rhomboid family Polysacc_synt_C PF14667.1 EAU84584.2 - 0.0046 16.7 4.6 0.017 14.9 3.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain RseC_MucC PF04246.7 EAU84584.2 - 0.53 9.8 1.8 8.4 5.9 0.2 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC CLASP_N PF12348.3 EAU84585.2 - 7.1e-67 225.0 0.7 1e-60 204.9 0.0 3.5 3 1 1 4 4 4 2 CLASP N terminal HEAT PF02985.17 EAU84585.2 - 9.9e-07 28.3 1.7 0.73 10.0 0.1 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EAU84585.2 - 0.00019 21.8 3.6 0.84 10.2 0.0 4.4 3 0 0 3 3 3 2 HEAT-like repeat AAA PF00004.24 EAU84587.1 - 5.5e-33 113.9 0.0 8.6e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU84587.1 - 8.6e-09 35.6 0.0 3.5e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU84587.1 - 9.9e-08 32.1 0.1 2.1e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAU84587.1 - 9.2e-07 29.7 0.0 2.3e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU84587.1 - 1.4e-05 25.0 0.0 4.4e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EAU84587.1 - 2.7e-05 24.1 0.0 6.3e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EAU84587.1 - 2.7e-05 23.8 0.0 0.00021 20.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EAU84587.1 - 4.3e-05 23.8 0.0 8.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAU84587.1 - 4.9e-05 22.8 0.4 0.043 13.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EAU84587.1 - 6.1e-05 22.8 0.1 0.0035 17.0 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EAU84587.1 - 8.4e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU84587.1 - 8.6e-05 22.2 0.0 0.00015 21.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EAU84587.1 - 0.00012 21.1 0.1 0.015 14.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EAU84587.1 - 0.00051 19.7 0.2 0.0029 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EAU84587.1 - 0.00081 19.0 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EAU84587.1 - 0.001 17.8 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus KAP_NTPase PF07693.9 EAU84587.1 - 0.0013 17.7 0.0 0.31 9.9 0.0 2.3 1 1 1 2 2 2 1 KAP family P-loop domain AAA_24 PF13479.1 EAU84587.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAU84587.1 - 0.0017 17.7 0.0 0.004 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EAU84587.1 - 0.0018 18.2 0.0 0.005 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EAU84587.1 - 0.0019 17.3 0.0 0.0067 15.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EAU84587.1 - 0.0019 17.8 0.1 0.0042 16.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EAU84587.1 - 0.0023 18.0 0.0 0.0069 16.5 0.0 1.8 2 0 0 2 2 1 1 RNA helicase Viral_helicase1 PF01443.13 EAU84587.1 - 0.0025 17.3 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EAU84587.1 - 0.0047 16.5 0.1 0.025 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EAU84587.1 - 0.0064 15.5 0.0 0.0088 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EAU84587.1 - 0.0096 16.2 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EAU84587.1 - 0.018 14.6 0.0 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EAU84587.1 - 0.021 15.1 0.0 0.05 13.8 0.0 1.8 2 0 0 2 2 1 0 ABC transporter PhoH PF02562.11 EAU84587.1 - 0.021 14.0 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.7 EAU84587.1 - 0.023 13.8 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.7 EAU84587.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 EAU84587.1 - 0.046 12.8 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EAU84587.1 - 0.048 13.1 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EAU84587.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EAU84587.1 - 0.081 12.0 0.3 1.3 8.1 0.0 2.4 2 1 1 3 3 3 0 KaiC PduV-EutP PF10662.4 EAU84587.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PPR_2 PF13041.1 EAU84588.2 - 0.042 13.8 0.0 0.49 10.4 0.0 2.5 3 0 0 3 3 3 0 PPR repeat family LSM PF01423.17 EAU84589.1 - 2.2e-18 65.5 0.0 2.4e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EAU84589.1 - 0.085 12.6 0.0 0.098 12.4 0.0 1.3 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DUF3722 PF12519.3 EAU84591.1 - 8.4e-97 323.4 0.0 1.1e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EAU84591.1 - 0.00092 18.5 0.0 1.3 8.2 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic porin Pkinase PF00069.20 EAU84593.2 - 5.2e-36 124.1 0.0 1.5e-35 122.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84593.2 - 5.8e-32 110.7 0.0 1.1e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU84593.2 - 0.053 12.4 0.0 0.096 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EAU84593.2 - 0.072 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FeoC PF09012.5 EAU84593.2 - 0.25 11.0 1.7 0.29 10.8 0.1 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator Pkr1 PF08636.5 EAU84594.1 - 6.4e-14 51.7 1.6 8.1e-14 51.4 1.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF2244 PF10003.4 EAU84594.1 - 0.29 10.5 1.8 0.34 10.2 1.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Sld5 PF05916.6 EAU84595.1 - 6.6e-07 29.5 0.0 1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF1860 PF08949.5 EAU84595.1 - 0.11 12.1 0.2 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) EMP24_GP25L PF01105.19 EAU84599.1 - 1.6e-39 135.4 0.0 1.9e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Acetyltransf_7 PF13508.1 EAU84600.2 - 0.00023 21.2 0.0 0.0007 19.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU84600.2 - 0.016 15.0 0.2 0.061 13.1 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain BAR_2 PF10455.4 EAU84601.1 - 3.8e-48 163.8 0.2 1.1e-47 162.3 0.1 1.6 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EAU84601.1 - 3.6e-13 49.5 0.0 1.6e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 BAR domain Uds1 PF15456.1 EAU84601.1 - 0.082 12.9 2.2 2.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Up-regulated During Septation p450 PF00067.17 EAU84602.2 - 7.3e-67 225.8 0.0 2.2e-66 224.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU84603.2 - 1.1e-64 218.7 0.0 4.1e-64 216.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PP2C PF00481.16 EAU84604.2 - 4.2e-05 23.0 0.1 0.0074 15.7 0.0 2.6 3 0 0 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.7 EAU84604.2 - 0.00035 20.3 0.0 0.0042 16.7 0.0 2.5 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EAU84604.2 - 0.0004 19.8 0.2 0.011 15.2 0.0 2.6 2 1 0 2 2 2 1 Protein phosphatase 2C tRNA-synt_1 PF00133.17 EAU84605.1 - 3.1e-215 715.7 0.0 1.4e-214 713.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAU84605.1 - 6.9e-35 120.0 0.1 1.5e-34 118.9 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAU84605.1 - 2.1e-16 59.6 3.2 1.8e-08 33.4 0.0 4.8 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EAU84605.1 - 5.8e-13 48.5 0.1 1.4e-08 34.2 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EAU84605.1 - 0.02 14.0 0.0 0.44 9.6 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ATG11 PF10377.4 EAU84605.1 - 0.033 14.0 0.0 0.033 14.0 0.0 1.9 2 0 0 2 2 2 0 Autophagy-related protein 11 tRNA-synt_1d PF00750.14 EAU84605.1 - 0.051 12.3 0.0 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) dUTPase PF00692.14 EAU84606.1 - 6.9e-42 141.9 0.0 8.3e-42 141.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase Glu-tRNAGln PF02686.10 EAU84607.1 - 0.13 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF4531 PF15041.1 EAU84608.1 - 0.13 11.9 4.2 4 7.1 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4531) Peptidase_M43 PF05572.8 EAU84609.2 - 5e-20 71.6 0.0 7.6e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU84609.2 - 3.1e-06 27.2 0.1 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAU84609.2 - 1.1e-05 25.5 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAU84609.2 - 0.00043 20.8 0.1 0.00069 20.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU84609.2 - 0.00084 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EAU84609.2 - 0.017 13.9 0.7 0.023 13.5 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 MBOAT PF03062.14 EAU84610.2 - 1.6e-46 158.9 27.8 1.6e-46 158.9 19.3 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ACBP PF00887.14 EAU84611.2 - 2.5e-22 78.3 0.0 4.2e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein DUF605 PF04652.11 EAU84611.2 - 1.6 8.0 11.6 2.3 7.5 8.0 1.3 1 0 0 1 1 1 0 Vta1 like ADH_N PF08240.7 EAU84612.1 - 9.8e-27 92.8 1.2 2e-26 91.8 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU84612.1 - 1e-18 67.1 0.1 1.7e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EAU84612.1 - 0.00091 18.4 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EAU84612.1 - 0.0071 15.9 0.1 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_S9 PF00380.14 EAU84612.1 - 0.082 13.1 0.0 1.7 8.9 0.0 2.4 1 1 1 2 2 2 0 Ribosomal protein S9/S16 ThiF PF00899.16 EAU84612.1 - 0.099 12.4 1.6 0.78 9.5 0.6 2.3 1 1 0 2 2 2 0 ThiF family COX15-CtaA PF02628.10 EAU84615.2 - 1e-91 306.9 11.8 1.3e-91 306.6 8.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BolA PF01722.13 EAU84616.1 - 3.9e-16 58.7 0.0 8e-16 57.7 0.0 1.5 1 1 1 2 2 2 1 BolA-like protein PQQ_2 PF13360.1 EAU84617.2 - 2.1e-05 24.1 0.2 0.011 15.1 0.0 3.2 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EAU84617.2 - 6.1e-05 22.3 0.1 0.048 13.1 0.0 4.2 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_3 PF13570.1 EAU84617.2 - 0.0012 19.0 11.2 0.49 10.7 0.0 5.9 6 1 0 6 6 6 2 PQQ-like domain Methyltransf_16 PF10294.4 EAU84618.2 - 5.8e-49 165.8 0.0 9.3e-49 165.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAU84618.2 - 8.2e-07 29.5 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU84618.2 - 0.00083 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAU84618.2 - 0.0033 16.5 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EAU84618.2 - 0.0038 16.9 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU84618.2 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EAU84618.2 - 0.011 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FimH_man-bind PF09160.5 EAU84618.2 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 FimH, mannose binding BTB PF00651.26 EAU84620.1 - 3.3e-06 27.0 0.0 7.6e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain FH2 PF02181.18 EAU84626.2 - 6.4e-88 295.1 0.0 6.4e-88 295.1 0.0 3.3 3 1 1 4 4 4 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EAU84626.2 - 1.2e-26 93.2 0.5 8e-21 74.2 0.3 2.5 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EAU84626.2 - 7.1e-21 74.5 0.1 7.1e-21 74.5 0.1 2.5 2 1 0 2 2 2 1 Diaphanous FH3 Domain TSC22 PF01166.13 EAU84626.2 - 0.61 10.0 14.8 1.3 9.0 1.4 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family TMF_TATA_bd PF12325.3 EAU84626.2 - 0.77 9.5 18.8 0.037 13.7 0.2 3.8 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 EAU84626.2 - 2.2 7.1 19.0 18 4.1 0.3 3.5 3 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 EAU84626.2 - 2.4 8.0 7.9 1.2 8.9 0.6 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 EAU84626.2 - 2.6 8.1 20.3 0.29 11.1 3.5 4.0 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 EAU84626.2 - 6.6 6.2 13.7 7.5 6.0 0.5 3.8 3 1 1 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tubulin PF00091.20 EAU84627.1 - 6.7e-68 228.7 0.0 8.8e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAU84627.1 - 1.6e-46 157.4 0.0 2.4e-46 156.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EAU84627.1 - 0.00017 21.1 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EAU84627.1 - 0.033 13.7 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) HAD_2 PF13419.1 EAU84628.1 - 4e-16 59.7 0.0 5.5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU84628.1 - 6.5e-13 48.1 0.0 1.2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EAU84628.1 - 2.6e-09 37.7 0.1 1.6e-06 28.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU84628.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sec15 PF04091.7 EAU84629.2 - 7.5e-71 238.9 0.2 1.8e-70 237.7 0.1 1.7 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 EAU84629.2 - 3.7e-08 33.3 0.6 3.7e-08 33.3 0.4 3.4 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Sec5 PF15469.1 EAU84629.2 - 3.9e-05 23.4 0.4 0.0002 21.1 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Sec8_exocyst PF04048.9 EAU84629.2 - 4.6e-05 23.0 1.8 0.00016 21.3 1.2 2.0 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps51 PF08700.6 EAU84629.2 - 0.00014 21.6 0.5 0.00014 21.6 0.4 3.4 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 EAU84629.2 - 0.0028 17.5 3.6 0.02 14.7 1.0 2.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Arf PF00025.16 EAU84630.1 - 2e-79 264.8 0.1 2.3e-79 264.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAU84630.1 - 2.7e-14 52.7 0.0 3.4e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EAU84630.1 - 5.6e-13 48.5 0.0 5.9e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EAU84630.1 - 1.9e-12 46.5 1.2 3.7e-09 35.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EAU84630.1 - 3.9e-11 42.5 0.0 4.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAU84630.1 - 2.2e-09 37.8 0.0 3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAU84630.1 - 5.1e-06 26.4 0.0 6.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU84630.1 - 0.0065 15.9 0.1 0.057 12.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EAU84630.1 - 0.0067 15.5 0.4 0.014 14.5 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EAU84630.1 - 0.054 13.3 0.2 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EAU84630.1 - 0.13 11.7 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Chromate_transp PF02417.10 EAU84631.2 - 5.8e-55 185.4 28.2 1.6e-30 105.8 9.5 2.3 2 0 0 2 2 2 2 Chromate transporter DUF2076 PF09849.4 EAU84632.2 - 0.23 11.4 5.3 0.3 11.1 3.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF605 PF04652.11 EAU84632.2 - 2.6 7.3 8.9 3.2 7.0 6.2 1.1 1 0 0 1 1 1 0 Vta1 like Chs3p PF12271.3 EAU84633.1 - 0.37 9.7 6.2 0.5 9.2 4.3 1.3 1 0 0 1 1 1 0 Chitin synthase III catalytic subunit DUF3245 PF11595.3 EAU84634.2 - 1.6e-06 28.4 1.1 1.6e-06 28.4 0.8 3.7 2 2 2 4 4 4 2 Protein of unknown function (DUF3245) DUF2702 PF10863.3 EAU84634.2 - 0.0049 16.6 0.8 0.0049 16.6 0.5 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2702) Soyouz_module PF14313.1 EAU84634.2 - 0.021 14.4 0.2 0.047 13.2 0.1 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SIP1 PF04938.7 EAU84635.2 - 1.1e-11 44.5 6.4 4.3e-05 22.9 0.1 2.7 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF2762 PF10960.3 EAU84635.2 - 0.58 9.9 2.5 1.6 8.5 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) Acetyltransf_7 PF13508.1 EAU84636.1 - 1.8e-07 31.2 0.0 3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU84636.1 - 1.8e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAU84636.1 - 6.7e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU84636.1 - 0.00024 20.9 0.0 0.00076 19.3 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAU84636.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein GPI-anchored PF10342.4 EAU84637.1 - 4.5e-09 36.6 0.5 1.5e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box-like PF12937.2 EAU84638.1 - 0.0015 18.2 0.7 0.012 15.3 0.0 2.7 2 0 0 2 2 2 1 F-box-like GPI-anchored PF10342.4 EAU84639.2 - 1.5e-10 41.3 1.2 2.1e-10 40.9 0.1 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Chromate_transp PF02417.10 EAU84640.1 - 3.3e-53 179.7 35.8 4.6e-30 104.4 9.6 2.4 3 0 0 3 3 3 2 Chromate transporter QRPTase_C PF01729.14 EAU84641.2 - 6.7e-49 165.6 0.0 8.1e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EAU84641.2 - 2.6e-22 78.4 0.0 8.5e-22 76.7 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF1341 PF07071.6 EAU84641.2 - 0.003 17.1 0.0 0.057 12.9 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1341) ECH PF00378.15 EAU84645.2 - 3.2e-54 183.6 0.0 4e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EAU84645.2 - 0.043 13.9 0.1 0.091 12.9 0.1 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Sec10 PF07393.6 EAU84646.2 - 3.3e-217 723.0 0.1 5.4e-217 722.3 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 Peptidase_S46 PF10459.4 EAU84646.2 - 0.041 12.3 1.1 0.069 11.5 0.7 1.3 1 0 0 1 1 1 0 Peptidase S46 RIX1 PF08167.7 EAU84647.2 - 9e-18 64.4 6.1 3e-17 62.7 1.5 2.6 2 1 1 3 3 3 2 rRNA processing/ribosome biogenesis TPR_11 PF13414.1 EAU84648.1 - 0.018 14.7 1.1 0.27 10.9 0.8 2.2 1 1 1 2 2 2 0 TPR repeat TPR_14 PF13428.1 EAU84648.1 - 0.031 14.8 0.8 7.7 7.4 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU84648.1 - 0.072 13.0 0.2 0.34 10.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAU84648.1 - 0.083 13.2 1.0 5.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4588 PF15251.1 EAU84648.1 - 0.094 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) TPR_1 PF00515.23 EAU84648.1 - 0.13 11.9 0.1 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_I_TF PF04090.7 EAU84648.1 - 0.15 11.3 0.2 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor PBP PF01161.15 EAU84653.2 - 5.8e-09 35.9 0.0 8.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CarboxypepD_reg PF13620.1 EAU84653.2 - 0.088 12.8 1.8 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain RRM_1 PF00076.17 EAU84654.1 - 2.4e-18 65.5 1.7 2.5e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84654.1 - 9.9e-14 51.0 0.4 1.8e-13 50.2 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU84654.1 - 1.6e-09 37.5 0.0 1.6e-09 37.5 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Toxin_ToxA PF11584.3 EAU84654.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA RRM_3 PF08777.6 EAU84654.1 - 0.093 12.5 0.3 0.27 11.0 0.2 1.7 1 1 0 1 1 1 0 RNA binding motif DEAD PF00270.24 EAU84657.1 - 1e-41 142.2 0.1 2.1e-41 141.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU84657.1 - 8.5e-28 96.0 0.2 1.8e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EAU84657.1 - 0.0077 15.9 0.1 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EAU84657.1 - 0.011 15.6 0.0 0.034 13.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU84657.1 - 0.031 14.4 0.2 0.12 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EAU84657.1 - 0.049 12.7 0.0 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.16 EAU84657.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3449 PF11931.3 EAU84658.2 - 1.8e-64 216.8 0.3 1.8e-64 216.8 0.2 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3449) zf-met PF12874.2 EAU84658.2 - 4.8e-06 26.5 4.5 1.3e-05 25.2 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.3 EAU84658.2 - 1.1e-05 24.8 0.2 3.1e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EAU84658.2 - 7.4e-05 22.7 0.2 7.4e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding DUF951 PF06107.6 EAU84658.2 - 0.058 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-C2H2_2 PF12756.2 EAU84658.2 - 0.13 12.3 1.5 0.4 10.8 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Syja_N PF02383.13 EAU84659.2 - 5.5e-79 265.2 0.0 7.9e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Erv26 PF04148.8 EAU84659.2 - 1.4e-63 214.1 9.7 2.3e-63 213.4 6.7 1.3 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Exo_endo_phos PF03372.18 EAU84659.2 - 9.1e-25 88.0 0.2 1.6e-24 87.1 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Snf7 PF03357.16 EAU84660.2 - 4.4e-17 61.9 14.9 5.7e-17 61.6 10.3 1.2 1 0 0 1 1 1 1 Snf7 Prominin PF05478.6 EAU84660.2 - 0.75 7.2 5.7 0.84 7.0 4.0 1.0 1 0 0 1 1 1 0 Prominin DUF1098 PF06497.6 EAU84660.2 - 3.5 7.7 8.8 18 5.4 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1098) Abhydrolase_1 PF00561.15 EAU84662.1 - 1.6e-17 63.8 0.0 3.4e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU84662.1 - 9.3e-11 42.0 1.1 6.1e-10 39.3 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EAU84662.1 - 0.012 14.9 0.2 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Snf7 PF03357.16 EAU84663.1 - 3.4e-45 153.4 13.9 4e-45 153.2 9.7 1.0 1 0 0 1 1 1 1 Snf7 FlxA PF14282.1 EAU84663.1 - 0.017 15.0 14.3 0.026 14.4 3.3 2.3 1 1 1 2 2 2 0 FlxA-like protein NPV_P10 PF05531.7 EAU84663.1 - 0.023 14.9 1.7 0.2 11.9 0.1 2.6 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.6 EAU84663.1 - 0.047 13.5 4.0 3.1 7.7 0.0 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1569 PF07606.6 EAU84663.1 - 0.07 13.0 1.5 0.1 12.4 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1569) Coat_F PF07875.7 EAU84663.1 - 0.07 13.2 2.5 0.11 12.6 1.4 1.6 1 1 0 1 1 1 0 Coat F domain Prefoldin_2 PF01920.15 EAU84663.1 - 0.087 12.5 14.6 2.2 8.0 0.0 3.7 2 1 1 3 3 3 0 Prefoldin subunit Mnd1 PF03962.10 EAU84663.1 - 0.12 12.0 13.1 0.58 9.7 9.1 2.0 1 1 0 1 1 1 0 Mnd1 family YppG PF14179.1 EAU84663.1 - 0.16 12.5 1.7 0.27 11.8 1.2 1.3 1 0 0 1 1 1 0 YppG-like protein Exonuc_VII_L PF02601.10 EAU84663.1 - 0.31 10.1 8.8 0.39 9.8 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-C4H2 PF10146.4 EAU84663.1 - 1.3 8.9 12.8 1.4 8.9 8.1 1.6 1 1 1 2 2 2 0 Zinc finger-containing protein DUF342 PF03961.8 EAU84663.1 - 2.7 6.3 12.3 1.1 7.5 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) MerR-DNA-bind PF09278.6 EAU84663.1 - 4.7 7.6 7.0 6.2 7.2 0.0 3.4 2 2 0 3 3 3 0 MerR, DNA binding TMF_TATA_bd PF12325.3 EAU84663.1 - 5.1 6.8 18.1 6.5e+02 0.0 4.5 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BTB PF00651.26 EAU84666.2 - 1.1e-06 28.5 0.0 3.6e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Vps52 PF04129.7 EAU84667.2 - 1.7e-59 201.7 2.9 8.2e-40 136.7 0.1 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 EAU84667.2 - 5.6e-07 28.0 0.1 0.00031 19.0 0.4 2.6 2 1 0 2 2 2 2 Exocyst complex component Sec3 DUF4201 PF13870.1 EAU84667.2 - 0.02 14.3 1.4 0.057 12.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) COG2 PF06148.6 EAU84667.2 - 0.021 14.7 1.3 0.1 12.4 0.3 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3508 PF12018.3 EAU84667.2 - 0.043 12.7 2.5 0.13 11.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3508) THOC7 PF05615.8 EAU84668.2 - 9.9e-20 71.2 4.2 9.9e-20 71.2 2.9 1.9 2 1 0 2 2 2 1 Tho complex subunit 7 Transposase_22 PF02994.9 EAU84668.2 - 0.00019 20.0 3.9 0.00019 20.0 2.7 1.7 2 0 0 2 2 2 1 L1 transposable element DUF4515 PF14988.1 EAU84668.2 - 0.0045 16.6 8.4 0.0072 16.0 5.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) DUF87 PF01935.12 EAU84668.2 - 0.01 15.6 0.5 0.056 13.2 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF842 PF05811.8 EAU84668.2 - 0.041 13.3 1.1 0.083 12.3 0.4 1.8 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) AAA_13 PF13166.1 EAU84668.2 - 0.09 11.2 4.1 0.16 10.3 2.8 1.4 1 0 0 1 1 1 0 AAA domain DUF2951 PF11166.3 EAU84668.2 - 0.36 10.7 3.1 3.6 7.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) HALZ PF02183.13 EAU84668.2 - 0.69 9.6 5.6 0.94 9.2 0.6 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper Atg14 PF10186.4 EAU84668.2 - 1.5 7.7 7.6 2.1 7.1 5.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EAU84668.2 - 1.6 8.2 8.0 20 4.6 5.3 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vps5 PF09325.5 EAU84670.1 - 1.9e-19 69.8 2.2 2.6e-19 69.4 1.5 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EAU84670.1 - 2.5e-10 40.1 0.0 5.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 PX domain Glyco_hydro_17 PF00332.13 EAU84671.2 - 6.4e-10 38.5 0.2 5.3e-09 35.5 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 UPF0016 PF01169.14 EAU84671.2 - 0.098 12.8 0.0 0.48 10.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 GTP_cyclohydro2 PF00925.15 EAU84672.1 - 1.9e-60 202.9 0.0 6.2e-55 185.0 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II PAP1 PF08601.5 EAU84672.1 - 0.14 11.7 0.7 0.23 11.0 0.5 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 DUF904 PF06005.7 EAU84673.1 - 0.019 15.2 8.7 0.2 11.9 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF342 PF03961.8 EAU84673.1 - 0.08 11.3 1.1 0.12 10.8 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) HALZ PF02183.13 EAU84673.1 - 0.13 12.0 7.4 0.33 10.7 0.1 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF4025 PF13217.1 EAU84673.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF4025) Jnk-SapK_ap_N PF09744.4 EAU84673.1 - 0.2 11.6 3.5 0.35 10.8 2.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF2730 PF10805.3 EAU84673.1 - 0.24 11.1 1.3 0.5 10.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Mod_r PF07200.8 EAU84673.1 - 0.27 11.1 9.4 0.54 10.1 5.1 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.3 EAU84673.1 - 0.29 10.8 11.2 0.16 11.6 1.4 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Syntaxin_2 PF14523.1 EAU84673.1 - 0.67 10.0 8.1 0.098 12.6 2.2 2.2 2 1 0 2 2 2 0 Syntaxin-like protein DUF4201 PF13870.1 EAU84673.1 - 0.71 9.2 6.3 2.7 7.3 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 EAU84673.1 - 1.8 8.9 10.5 4.3 7.7 3.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 EAU84673.1 - 5.7 6.7 9.5 0.46 10.3 0.4 2.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFR_dimer PF04253.10 EAU84674.2 - 5.2e-11 42.1 0.0 1.5e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EAU84674.2 - 4e-07 29.9 0.0 3e-06 27.0 0.0 2.5 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAU84674.2 - 4.2e-06 26.3 0.0 9.1e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF282 PF03380.9 EAU84675.1 - 0.046 13.4 0.3 0.19 11.4 0.2 2.1 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 CENP-R PF06729.7 EAU84676.2 - 1.7 8.3 8.1 2.7 7.6 0.2 3.1 2 1 1 3 3 3 0 Kinetochore component, CENP-R JAB PF01398.16 EAU84677.1 - 2.4e-35 120.6 0.1 4.3e-35 119.9 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EAU84677.1 - 1.8e-28 98.9 3.3 2.1e-28 98.7 1.4 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EAU84677.1 - 8.2e-09 34.9 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EAU84677.1 - 0.012 15.1 0.6 0.065 12.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.15 EAU84678.1 - 6.9e-15 54.6 0.5 9.9e-15 54.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 UIM PF02809.15 EAU84680.2 - 0.00059 19.1 12.2 0.024 14.1 0.8 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif Ribonuc_red_sm PF00268.16 EAU84681.2 - 2.6e-114 381.0 0.1 3e-114 380.7 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Ribonuc_red_sm PF00268.16 EAU84682.1 - 1.7e-121 404.5 1.9 2.1e-121 404.2 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Alg6_Alg8 PF03155.10 EAU84684.2 - 6.6e-100 335.1 24.9 8.3e-100 334.8 17.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family LSR PF05624.9 EAU84687.1 - 2.7 7.7 8.0 0.82 9.4 1.3 2.5 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) V-SNARE_C PF12352.3 EAU84688.2 - 9.2e-17 60.8 6.1 1.7e-16 60.0 3.6 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EAU84688.2 - 1.3e-07 31.6 8.3 4.8e-06 26.6 1.1 3.6 2 2 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 EAU84688.2 - 0.00019 21.0 0.4 0.00055 19.5 0.2 1.8 1 0 0 1 1 1 1 Sec20 Phospholamban PF04272.9 EAU84688.2 - 0.0042 16.5 1.4 0.042 13.2 0.1 2.4 2 0 0 2 2 2 1 Phospholamban Sec8_exocyst PF04048.9 EAU84688.2 - 0.013 15.1 1.8 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain YqjK PF13997.1 EAU84688.2 - 0.035 14.2 1.1 0.035 14.2 0.7 2.3 2 1 1 3 3 3 0 YqjK-like protein Imm43 PF15602.1 EAU84688.2 - 0.12 12.3 0.3 0.32 10.9 0.1 1.7 1 1 1 2 2 2 0 Immunity protein 43 Prominin PF05478.6 EAU84688.2 - 0.13 9.7 1.3 0.56 7.6 0.1 1.9 2 0 0 2 2 2 0 Prominin ApoLp-III PF07464.6 EAU84688.2 - 0.18 11.8 5.2 0.56 10.2 0.6 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF3619 PF12279.3 EAU84688.2 - 0.24 11.4 6.6 2.2 8.3 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) DUF2721 PF11026.3 EAU84688.2 - 2.6 7.6 6.3 0.3 10.7 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Exonuc_VII_L PF02601.10 EAU84688.2 - 3.4 6.7 9.1 24 3.9 6.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF106 PF01956.11 EAU84689.2 - 4.1e-37 127.2 13.1 2.1e-34 118.4 5.5 2.3 1 1 1 2 2 2 2 Integral membrane protein DUF106 EF-hand_1 PF00036.27 EAU84690.2 - 1.7e-24 83.1 12.5 4.3e-08 31.8 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EAU84690.2 - 5.9e-23 80.7 6.5 5.3e-14 52.0 0.9 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAU84690.2 - 1e-20 71.6 5.2 9.7e-06 25.0 0.1 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EAU84690.2 - 1.6e-14 52.4 12.7 0.00014 20.9 0.3 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EAU84690.2 - 2.9e-13 49.1 9.9 5.2e-07 29.1 0.3 3.8 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAU84690.2 - 1.1e-07 31.9 0.7 1.5e-05 25.0 0.0 2.5 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EAU84690.2 - 5.6e-07 29.2 6.0 0.053 13.2 0.1 4.0 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EAU84690.2 - 2.3e-06 27.3 1.0 0.017 15.0 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain EF-hand_2 PF09068.6 EAU84690.2 - 0.022 14.8 0.1 5.4 7.0 0.0 3.1 3 1 0 3 3 3 0 EF hand S10_plectin PF03501.10 EAU84690.2 - 0.022 14.5 0.0 0.035 13.9 0.0 1.5 1 1 0 1 1 1 0 Plectin/S10 domain TerB PF05099.8 EAU84690.2 - 0.036 13.8 0.0 7.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB DUF3231 PF11553.3 EAU84690.2 - 0.049 13.1 0.1 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3231) EF-hand_10 PF14788.1 EAU84690.2 - 0.065 12.9 4.6 8.9 6.0 0.4 4.0 4 1 0 4 4 4 0 EF hand WD40 PF00400.27 EAU84692.1 - 0.0015 18.3 0.1 1.2 9.1 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1513 PF07433.6 EAU84692.1 - 0.13 11.0 0.0 0.38 9.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DASH_Dad4 PF08650.5 EAU84693.1 - 9e-20 70.3 0.4 9.8e-20 70.2 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Peptidase_M18 PF02127.10 EAU84696.1 - 5.3e-159 529.3 0.0 6e-159 529.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EAU84696.1 - 3.7e-05 22.6 0.0 0.0018 17.1 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase WD40 PF00400.27 EAU84697.2 - 2.1e-76 249.2 24.6 9.2e-10 38.0 0.1 11.8 12 0 0 12 12 12 11 WD domain, G-beta repeat Utp12 PF04003.7 EAU84697.2 - 5.3e-19 68.1 0.4 8.7e-19 67.4 0.2 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EAU84697.2 - 5.2e-07 28.1 3.3 0.014 13.6 0.0 4.0 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EAU84697.2 - 3.2e-05 23.3 0.0 1.8 8.1 0.0 4.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EAU84697.2 - 9.3e-05 21.3 4.7 2 7.0 0.1 5.7 2 2 3 7 7 7 1 Nup133 N terminal like Coatomer_WDAD PF04053.9 EAU84697.2 - 0.0092 14.8 0.0 0.23 10.2 0.0 2.7 2 1 1 3 3 3 1 Coatomer WD associated region Med16 PF11635.3 EAU84697.2 - 0.013 13.4 0.1 0.56 8.0 0.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 16 DPBB_1 PF03330.13 EAU84698.1 - 7.3e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Fungal_trans PF04082.13 EAU84699.2 - 9.9e-24 83.6 0.4 2.9e-23 82.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain UPF0233 PF06781.7 EAU84701.1 - 0.06 12.9 0.8 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) SNARE_assoc PF09335.6 EAU84702.1 - 8.5e-16 58.2 7.4 8.5e-16 58.2 5.1 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein Syntaxin-18_N PF10496.4 EAU84703.1 - 3.1e-09 36.5 0.1 1.7e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EAU84703.1 - 0.21 11.2 6.2 0.13 11.9 2.3 2.2 2 0 0 2 2 2 0 SNARE domain Ssu72 PF04722.8 EAU84704.2 - 1.5e-81 272.4 0.0 1.9e-81 272.0 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein Zn_clus PF00172.13 EAU84706.2 - 1.3e-07 31.4 13.4 2e-07 30.7 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 EAU84706.2 - 4.2 5.3 5.5 5.7 4.9 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) E1-E2_ATPase PF00122.15 EAU84709.1 - 5.2e-66 221.9 2.6 9.5e-66 221.1 1.8 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAU84709.1 - 3.6e-31 108.1 4.8 3.6e-31 108.1 3.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAU84709.1 - 9.1e-26 91.5 0.2 2.2e-24 87.0 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAU84709.1 - 1.6e-16 59.5 0.1 1.6e-16 59.5 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EAU84709.1 - 1.2e-14 53.9 0.0 2.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAU84709.1 - 4.6e-13 49.7 0.0 1e-12 48.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAU84709.1 - 0.002 17.7 0.9 0.0079 15.7 0.6 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.4 EAU84709.1 - 0.87 8.0 2.6 12 4.2 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) COX7C PF02935.11 EAU84710.1 - 1e-08 34.7 0.3 1.5e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc TetR_N PF00440.18 EAU84710.1 - 0.037 13.6 0.5 0.066 12.8 0.4 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Ribonuclease_3 PF00636.21 EAU84711.2 - 1.6e-37 128.4 0.0 5.9e-18 65.3 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EAU84711.2 - 8.8e-26 90.3 0.2 2.1e-09 37.3 0.0 4.5 4 0 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EAU84711.2 - 5.8e-07 29.2 0.0 1.4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EAU84711.2 - 0.00013 21.7 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.17 EAU84711.2 - 0.0018 17.5 0.0 0.0063 15.8 0.0 1.8 1 1 0 1 1 1 1 PAZ domain DEAD PF00270.24 EAU84711.2 - 0.016 14.6 0.1 0.047 13.1 0.1 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase Ank_5 PF13857.1 EAU84712.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Chromate_transp PF02417.10 EAU84713.1 - 0.011 15.3 2.2 0.011 15.3 1.5 1.7 1 1 1 2 2 2 0 Chromate transporter Hex_IIIa PF02455.11 EAU84715.2 - 0.018 13.7 2.9 0.026 13.2 2.0 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Auto_anti-p27 PF06677.7 EAU84716.2 - 1.4e-05 24.7 0.0 1.4e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Glyco_hydro_47 PF01532.15 EAU84717.2 - 1.2e-129 432.9 0.0 1.4e-129 432.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pribosyltran PF00156.22 EAU84718.1 - 2.3e-16 59.6 0.1 3.1e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EAU84718.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.6 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EAU84718.1 - 0.067 12.1 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like Ribosomal_S3Ae PF01015.13 EAU84719.1 - 3.7e-84 280.9 4.8 4.4e-84 280.6 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EAU84719.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region mRNA_cap_C PF03919.10 EAU84719.1 - 0.067 13.5 0.4 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain Dynamin_N PF00350.18 EAU84723.2 - 1.7e-09 37.7 0.7 1.7e-09 37.7 0.5 4.4 2 2 0 2 2 2 1 Dynamin family DUF258 PF03193.11 EAU84723.2 - 0.0018 17.4 0.0 0.0037 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EAU84723.2 - 0.0033 17.7 0.5 0.0033 17.7 0.3 3.4 4 1 0 4 4 4 1 ABC transporter MMR_HSR1 PF01926.18 EAU84723.2 - 0.018 15.0 3.0 0.19 11.7 2.1 2.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EAU84723.2 - 0.062 13.2 4.4 0.073 13.0 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.1 EAU84723.2 - 0.08 13.0 0.2 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAU84723.2 - 0.082 12.4 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain REV PF00424.13 EAU84724.2 - 0.59 10.0 5.9 0.95 9.3 3.9 1.6 1 1 0 1 1 1 0 REV protein (anti-repression trans-activator protein) ATP_bind_1 PF03029.12 EAU84725.1 - 3.3e-76 255.9 0.0 4.5e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EAU84725.1 - 1e-06 29.5 0.0 1.7e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EAU84725.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 EAU84725.1 - 0.00046 19.6 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU84725.1 - 0.0029 17.6 0.0 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ArsA_ATPase PF02374.10 EAU84725.1 - 0.004 16.2 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_18 PF13238.1 EAU84725.1 - 0.0065 16.7 0.0 0.017 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAU84725.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU84725.1 - 0.0076 16.1 0.2 0.078 12.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EAU84725.1 - 0.0087 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein Sigma54_activat PF00158.21 EAU84725.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 EAU84725.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EAU84725.1 - 0.069 12.7 0.0 0.094 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EAU84725.1 - 0.087 12.5 0.1 0.34 10.6 0.0 2.0 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.17 EAU84725.1 - 0.095 12.8 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EAU84725.1 - 0.098 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 EAU84725.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase APS_kinase PF01583.15 EAU84725.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_14 PF13173.1 EAU84725.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EAU84725.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 KaiC PF06745.8 EAU84725.1 - 0.17 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 KaiC Mago-bind PF09282.5 EAU84726.1 - 2.5e-12 46.1 1.0 4.7e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 Mago binding DREPP PF05558.7 EAU84726.1 - 0.16 11.8 9.7 0.21 11.3 6.7 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF1387 PF07139.6 EAU84726.1 - 0.24 10.9 5.4 0.32 10.5 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Pox_Ag35 PF03286.9 EAU84726.1 - 1 8.8 8.5 1.2 8.5 5.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NARP1 PF12569.3 EAU84726.1 - 5.1 5.7 9.3 6.1 5.4 6.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GCV_T PF01571.16 EAU84729.2 - 2.2e-10 40.2 0.0 3.8e-10 39.4 0.0 1.6 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EAU84729.2 - 0.0062 16.5 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Glycos_trans_3N PF02885.12 EAU84729.2 - 0.046 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain ACPS PF01648.15 EAU84730.2 - 1e-11 44.6 0.0 2.1e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily WD40 PF00400.27 EAU84731.2 - 5.4e-51 168.7 21.9 8.7e-10 38.1 0.0 10.6 10 0 0 10 10 10 9 WD domain, G-beta repeat HEM4 PF02602.10 EAU84731.2 - 0.012 14.8 0.2 0.18 10.9 0.0 2.4 3 0 0 3 3 3 0 Uroporphyrinogen-III synthase HemD HMG_box PF00505.14 EAU84736.2 - 2.2e-12 47.0 0.2 4e-12 46.2 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU84736.2 - 0.0003 21.1 0.0 0.00071 19.8 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EAU84736.2 - 0.062 12.6 0.5 0.25 10.6 0.1 2.1 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 DUF302 PF03625.9 EAU84737.1 - 1.9e-05 24.1 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF302 DEAD PF00270.24 EAU84738.2 - 2.5e-37 127.9 0.0 4.8e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU84738.2 - 6.9e-25 86.7 0.0 1.6e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU84738.2 - 0.084 12.6 1.4 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit BTB PF00651.26 EAU84739.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Mob1_phocein PF03637.12 EAU84740.2 - 3.5e-75 251.4 0.0 4.1e-75 251.2 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DJ-1_PfpI PF01965.19 EAU84741.2 - 3.3e-22 78.5 0.1 6.8e-22 77.5 0.1 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EAU84741.2 - 7.5e-11 41.3 0.5 1.5e-10 40.4 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family RRM_5 PF13893.1 EAU84742.2 - 1.2e-11 44.3 0.0 2e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU84742.2 - 4.5e-09 35.8 0.0 1.3e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84742.2 - 7.8e-05 22.5 0.0 0.00018 21.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2956 PF11169.3 EAU84742.2 - 0.072 13.0 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) CDC45 PF02724.9 EAU84742.2 - 0.14 10.2 0.7 0.16 9.9 0.5 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAM_LAG1_CLN8 PF03798.11 EAU84743.1 - 1.8e-45 154.9 25.8 2.5e-45 154.4 17.9 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EAU84743.1 - 2.5e-07 30.0 0.0 2.5e-07 30.0 0.0 2.3 3 0 0 3 3 3 1 TRAM1-like protein Snf7 PF03357.16 EAU84744.1 - 2.4e-37 127.9 23.6 2.4e-37 127.9 16.3 1.3 1 1 0 1 1 1 1 Snf7 Ribonuclease_3 PF00636.21 EAU84744.1 - 0.37 11.2 2.0 0.58 10.6 1.3 1.5 1 1 0 1 1 1 0 Ribonuclease III domain UPF0564 PF10595.4 EAU84744.1 - 0.58 9.0 11.7 0.56 9.0 4.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DUF29 PF01724.11 EAU84744.1 - 1 9.2 8.0 1.5 8.6 1.8 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF29 MCPVI PF02993.9 EAU84744.1 - 1 9.4 9.1 0.17 11.9 0.9 2.2 1 1 1 2 2 2 0 Minor capsid protein VI Birna_RdRp PF04197.7 EAU84744.1 - 1.3 6.9 7.9 1.4 6.8 5.5 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Tropomodulin PF03250.9 EAU84744.1 - 1.8 8.1 11.7 0.089 12.3 2.7 2.7 1 1 0 3 3 3 0 Tropomodulin NIF PF03031.13 EAU84745.2 - 4.8e-50 169.3 0.0 6.8e-50 168.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MFS_1 PF07690.11 EAU84746.2 - 1.2e-40 139.3 36.3 1.1e-38 132.8 19.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 EAU84747.1 - 8.7e-08 31.8 4.9 2.5e-06 27.2 1.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EAU84747.1 - 1.2e-05 25.3 0.3 2.2e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAU84747.1 - 3.4e-05 23.4 0.4 0.00012 21.6 0.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU84747.1 - 0.0011 18.9 2.8 0.0011 18.9 2.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EAU84747.1 - 0.0019 17.7 2.2 0.0038 16.7 0.5 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EAU84747.1 - 0.0038 16.8 2.9 0.012 15.2 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAU84747.1 - 0.0043 16.8 0.8 0.67 9.8 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EAU84747.1 - 0.034 13.8 3.6 0.059 13.1 1.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-met2 PF12907.2 EAU84747.1 - 0.044 13.7 0.4 6.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding zf-C3HC4_4 PF15227.1 EAU84747.1 - 0.066 13.0 0.8 0.066 13.0 0.5 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAU84747.1 - 0.24 11.1 1.5 0.59 9.8 1.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger tRNA-synt_2c PF01411.14 EAU84748.2 - 2.2e-05 22.9 0.0 3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EAU84748.2 - 0.00059 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Glyco_hydro_2 PF00703.16 EAU84749.2 - 1.3e-07 32.0 0.1 5.9e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EAU84749.2 - 5.9e-06 25.3 0.0 1.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EAU84749.2 - 0.00046 19.7 0.0 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Ras PF00071.17 EAU84750.1 - 3.1e-47 159.9 0.2 3.7e-47 159.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU84750.1 - 5.9e-15 55.8 0.1 9.3e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU84750.1 - 0.00019 20.7 0.0 0.00023 20.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EAU84750.1 - 0.00033 20.5 0.0 0.00041 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU84750.1 - 0.0025 17.2 0.3 0.013 14.9 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EAU84750.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EAU84750.1 - 0.011 14.9 0.1 0.013 14.6 0.1 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EAU84750.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase Spo12 PF05032.7 EAU84751.1 - 1.8e-11 43.4 0.2 3.2e-11 42.6 0.2 1.4 1 0 0 1 1 1 1 Spo12 family zf-RING_2 PF13639.1 EAU84752.2 - 5.9e-07 29.2 6.7 5.3e-06 26.1 4.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAU84752.2 - 8.7e-07 28.5 3.3 1.2e-05 24.9 2.3 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EAU84752.2 - 5.1e-06 26.5 2.5 8.7e-06 25.7 1.8 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAU84752.2 - 5.6e-06 26.2 1.7 5.6e-06 26.2 1.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU84752.2 - 6.5e-06 25.7 4.5 2.8e-05 23.6 3.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU84752.2 - 2.8e-05 23.6 1.7 0.00016 21.2 0.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.8 EAU84752.2 - 0.00011 21.8 0.4 0.0022 17.6 0.1 2.1 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-RING_UBOX PF13445.1 EAU84752.2 - 0.0003 20.4 1.7 0.0006 19.4 0.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAU84752.2 - 0.00038 20.2 0.3 0.00038 20.2 0.2 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EAU84752.2 - 0.00064 19.5 0.8 0.0045 16.7 0.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EAU84752.2 - 0.0017 17.7 0.4 0.0029 17.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EAU84752.2 - 0.0036 16.8 2.4 0.0057 16.2 0.6 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 EAU84752.2 - 0.044 12.9 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Chitin_synth_1 PF01644.12 EAU84753.2 - 2e-64 216.3 0.1 3.1e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EAU84753.2 - 1.5e-26 92.9 0.0 1.6e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EAU84753.2 - 3.1e-26 90.8 0.4 5.8e-26 89.9 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EAU84753.2 - 1.8e-12 47.3 0.1 1.8e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAU84753.2 - 1.3e-08 34.9 0.0 4.3e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GST_N_3 PF13417.1 EAU84754.2 - 2.8e-14 53.1 0.1 6.4e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU84754.2 - 6.8e-05 22.7 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU84754.2 - 0.0027 17.5 0.3 0.0053 16.6 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU84754.2 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU84754.2 - 0.11 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-CCHC PF00098.18 EAU84755.2 - 8.8e-20 69.6 19.8 8.3e-09 34.9 1.4 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 EAU84755.2 - 3.1e-06 26.8 2.3 0.24 11.1 1.0 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.1 EAU84755.2 - 0.0045 16.6 10.3 1 9.0 0.5 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 EAU84755.2 - 0.019 14.4 0.2 0.019 14.4 0.2 3.0 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_6 PF15288.1 EAU84755.2 - 2 8.1 16.0 0.8 9.4 1.7 3.3 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EAU84755.2 - 3.5 7.7 8.0 39 4.4 4.5 2.9 2 1 0 2 2 2 0 DnaJ central domain 14-3-3 PF00244.15 EAU84756.2 - 2e-50 171.1 0.2 2.5e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DS PF01916.12 EAU84757.1 - 1.5e-137 457.6 0.0 1.7e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sec7 PF01369.15 EAU84758.2 - 1.5e-60 204.1 0.0 4.3e-60 202.6 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EAU84758.2 - 1e-48 164.9 0.8 1e-48 164.9 0.6 3.9 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EAU84758.2 - 1.4e-27 95.0 0.1 1.4e-27 95.0 0.0 5.3 8 0 0 8 8 8 1 Domain of unknown function (DUF1981) SH3_9 PF14604.1 EAU84759.2 - 1.2e-39 133.6 7.2 6.8e-16 57.5 0.1 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 EAU84759.2 - 1.9e-39 132.8 5.6 1.4e-16 59.5 0.0 4.1 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EAU84759.2 - 9e-27 92.5 0.0 2.1e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 EAU84759.2 - 1.5e-25 88.4 0.1 1e-08 34.5 0.0 4.5 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EAU84759.2 - 3.4e-05 23.9 2.5 1.3 9.2 0.0 3.7 3 0 0 3 3 3 2 Bacterial SH3 domain hSH3 PF14603.1 EAU84759.2 - 0.15 12.0 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 Helically-extended SH3 domain GTP_EFTU PF00009.22 EAU84760.1 - 2.8e-47 160.5 0.1 5.5e-47 159.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAU84760.1 - 3.4e-26 91.2 0.1 1.1e-25 89.6 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAU84760.1 - 1.1e-08 35.0 0.1 3.6e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAU84760.1 - 3.3e-05 23.8 0.0 9e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAU84760.1 - 0.0036 17.7 0.0 0.018 15.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Glyco_hydro_3_C PF01915.17 EAU84760.1 - 0.025 14.1 0.1 0.062 12.8 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain G-alpha PF00503.15 EAU84760.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit PAM2 PF07145.10 EAU84760.1 - 0.28 10.7 2.6 0.18 11.3 0.2 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF605 PF04652.11 EAU84760.1 - 0.29 10.4 10.2 0.41 9.9 7.1 1.2 1 0 0 1 1 1 0 Vta1 like DUF2435 PF10363.4 EAU84761.2 - 2.7e-30 104.0 0.0 2.9e-29 100.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT PF02985.17 EAU84761.2 - 0.0074 16.2 0.2 1.7e+02 2.7 0.0 6.2 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.1 EAU84761.2 - 0.011 16.2 6.8 0.45 11.0 0.0 6.3 7 1 1 8 8 8 0 HEAT-like repeat UQ_con PF00179.21 EAU84763.2 - 1.9e-20 72.7 0.0 3.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 EAU84763.2 - 0.0003 20.5 0.7 0.00063 19.5 0.5 1.4 1 0 0 1 1 1 1 IBR domain Nop14 PF04147.7 EAU84763.2 - 2.2 6.0 7.6 3.4 5.4 5.3 1.2 1 0 0 1 1 1 0 Nop14-like family PepSY_TM_2 PF13703.1 EAU84764.1 - 0.061 13.4 0.1 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix Opy2 PF09463.5 EAU84764.1 - 0.13 12.3 14.7 0.21 11.7 10.2 1.3 1 0 0 1 1 1 0 Opy2 protein ABC_tran PF00005.22 EAU84765.2 - 1e-14 55.0 0.0 4.1e-14 53.0 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU84765.2 - 2.7e-07 30.8 1.8 0.00011 22.2 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAU84765.2 - 0.00023 20.6 0.1 0.00047 19.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EAU84765.2 - 0.00039 19.8 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EAU84765.2 - 0.00081 18.6 0.1 0.55 9.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EAU84765.2 - 0.00082 18.5 0.0 0.087 11.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EAU84765.2 - 0.002 17.3 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EAU84765.2 - 0.0093 15.4 0.2 0.021 14.2 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EAU84765.2 - 0.014 15.7 0.3 0.024 14.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EAU84765.2 - 0.046 13.6 1.1 0.055 13.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EAU84765.2 - 0.049 13.1 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EAU84765.2 - 0.07 13.9 3.0 0.27 12.0 2.1 2.2 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU84765.2 - 0.091 12.4 0.1 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EAU84765.2 - 0.094 12.1 0.6 0.2 11.0 0.4 1.6 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EAU84765.2 - 0.11 12.4 0.1 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 EAU84765.2 - 0.13 12.0 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.18 EAU84765.2 - 0.17 11.8 0.2 0.31 11.0 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EAU84765.2 - 0.17 12.0 1.1 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EAU84765.2 - 0.17 11.5 0.9 1.2 8.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) zf-CCHC PF00098.18 EAU84766.2 - 0.0014 18.4 1.8 0.0014 18.4 1.2 5.1 7 0 0 7 7 7 2 Zinc knuckle zf-CCHC_2 PF13696.1 EAU84766.2 - 6.9 6.2 11.9 0.47 9.9 0.5 3.1 3 0 0 3 3 3 0 Zinc knuckle CRA PF06589.6 EAU84766.2 - 7.3 5.8 8.1 16 4.8 0.8 2.7 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) zf-CCHC_4 PF14392.1 EAU84766.2 - 9.7 5.9 27.6 0.25 11.0 0.7 4.5 3 1 2 5 5 5 0 Zinc knuckle UQ_con PF00179.21 EAU84767.2 - 1.4e-14 53.7 0.0 1.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAU84767.2 - 0.015 15.1 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain His_Phos_2 PF00328.17 EAU84768.2 - 3.3e-85 286.4 0.3 4.8e-85 285.9 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EAU84768.2 - 8.1e-07 28.7 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain AMP-binding PF00501.23 EAU84769.2 - 6.5e-91 304.7 0.1 7.3e-90 301.3 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU84769.2 - 2.8e-11 44.1 1.2 7.3e-11 42.8 0.8 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RasGAP_C PF03836.10 EAU84770.2 - 1.5e-37 128.4 0.7 5.1e-37 126.7 0.5 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EAU84770.2 - 3.4e-32 111.7 0.0 3.4e-32 111.7 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EAU84770.2 - 1e-25 86.8 61.0 0.0061 16.1 0.1 13.9 13 0 0 13 13 13 12 IQ calmodulin-binding motif CH PF00307.26 EAU84770.2 - 2.3e-09 37.2 0.0 7.8e-09 35.5 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_LAMP2 PF06126.6 EAU84772.2 - 0.45 8.8 0.0 0.65 8.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Kelch_4 PF13418.1 EAU84773.2 - 2.1e-19 69.0 8.8 3e-05 23.6 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EAU84773.2 - 1.2e-17 63.5 26.6 0.00047 20.2 0.2 8.3 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EAU84773.2 - 3.7e-08 33.1 2.4 0.59 10.1 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EAU84773.2 - 8.2e-08 32.1 2.8 1.1 9.5 0.0 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EAU84773.2 - 3.1e-05 23.4 0.5 5.3 6.6 0.0 5.6 6 0 0 6 6 6 1 Kelch motif Cytochrom_B561 PF03188.11 EAU84773.2 - 0.0057 16.4 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Kelch_2 PF07646.10 EAU84773.2 - 0.11 12.3 2.4 14 5.6 0.0 4.4 5 0 0 5 5 5 0 Kelch motif DUF805 PF05656.9 EAU84773.2 - 0.51 10.1 7.0 0.53 10.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) zf-DHHC PF01529.15 EAU84773.2 - 4.5 6.6 3.8 6.9 6.0 0.3 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-C2H2 PF00096.21 EAU84774.2 - 2.2e-06 27.6 8.3 0.00011 22.3 0.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU84774.2 - 4.4e-06 26.7 14.7 0.00046 20.3 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU84774.2 - 0.00069 19.7 12.7 0.0012 19.0 0.4 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EAU84774.2 - 0.031 14.4 0.8 0.68 10.2 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAU84774.2 - 0.13 12.4 2.7 2.2 8.5 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EAU84774.2 - 3.2 8.1 15.2 0.39 11.0 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Cid2 PF09774.4 EAU84775.2 - 7.9e-18 64.9 5.1 2e-17 63.6 3.6 1.6 1 1 0 1 1 1 1 Caffeine-induced death protein 2 DUF2336 PF10098.4 EAU84775.2 - 0.021 14.0 0.1 0.023 13.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) GILT PF03227.11 EAU84776.2 - 1.3e-06 28.1 0.9 1.5e-06 27.9 0.1 1.5 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Prok-E2_A PF14457.1 EAU84776.2 - 0.0094 15.4 0.1 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family A Omega-toxin PF06357.6 EAU84776.2 - 0.13 11.8 0.2 0.38 10.3 0.1 1.8 1 0 0 1 1 1 0 Omega-atracotoxin Ribosomal_L22 PF00237.14 EAU84777.1 - 1.8e-17 63.1 0.2 1.8e-17 63.1 0.1 2.2 2 1 1 3 3 3 1 Ribosomal protein L22p/L17e F1F0-ATPsyn_F PF10791.4 EAU84777.1 - 0.42 10.8 2.9 1.5 9.1 0.3 2.5 2 1 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Ribophorin_I PF04597.9 EAU84778.1 - 2.1e-114 382.3 0.3 2.4e-114 382.2 0.2 1.0 1 0 0 1 1 1 1 Ribophorin I PPR_2 PF13041.1 EAU84780.1 - 7.9e-21 73.7 0.4 1.6e-11 43.9 0.0 4.7 4 0 0 4 4 4 4 PPR repeat family PPR PF01535.15 EAU84780.1 - 2.5e-14 52.1 0.3 0.0051 16.7 0.0 5.0 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.1 EAU84780.1 - 1.4e-08 34.2 0.5 0.046 14.0 0.0 5.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EAU84780.1 - 0.0014 18.0 0.5 0.015 14.7 0.1 2.7 2 0 0 2 2 2 1 PPR repeat TPR_14 PF13428.1 EAU84780.1 - 0.0018 18.7 0.0 7.9 7.4 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU84780.1 - 0.011 16.0 0.1 2.9 8.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4003 PF13170.1 EAU84780.1 - 0.098 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Asp PF00026.18 EAU84781.1 - 6.6e-25 88.0 0.0 6.1e-23 81.5 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.1 EAU84781.1 - 0.00043 20.0 0.2 1.1 9.1 0.1 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EAU84781.1 - 0.00054 20.4 0.2 2.8 8.5 0.0 3.1 3 1 0 3 3 3 2 Aspartyl protease Fe-ADH PF00465.14 EAU84782.1 - 4.5e-88 295.3 0.0 5.7e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EAU84782.1 - 5.8e-13 48.7 0.0 1.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase His_biosynth PF00977.16 EAU84783.2 - 8.3e-35 120.1 0.0 9.8e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 EAU84783.2 - 0.076 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4107 PF13389.1 EAU84783.2 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) Ribosomal_L29 PF00831.18 EAU84784.1 - 8.7e-19 66.9 1.2 8.7e-19 66.9 0.8 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 EAU84784.1 - 0.0064 16.3 1.6 0.0081 16.0 0.1 1.8 2 1 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_S9 PF00380.14 EAU84784.1 - 0.013 15.7 1.1 0.018 15.2 0.7 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 DUF607 PF04678.8 EAU84784.1 - 0.53 10.1 5.3 1.7 8.4 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF4248 PF14053.1 EAU84784.1 - 0.62 9.6 2.9 0.46 10.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF896 PF05979.7 EAU84784.1 - 1 9.0 7.0 0.11 12.0 1.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Fib_alpha PF08702.5 EAU84784.1 - 5 7.2 6.0 14 5.8 4.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Taeniidae_ag PF05596.6 EAU84784.1 - 5.7 6.8 6.3 1.4 8.8 0.2 2.5 3 0 0 3 3 3 0 Taeniidae antigen Pkinase PF00069.20 EAU84785.2 - 1.9e-70 236.9 0.0 2.7e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84785.2 - 2.4e-47 161.1 0.0 3.4e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU84785.2 - 4.1e-06 25.9 0.0 0.00016 20.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAU84785.2 - 0.071 12.8 0.0 8.6 6.0 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Perilipin PF03036.11 EAU84786.1 - 8e-08 31.5 16.8 2.1e-06 26.8 0.4 2.6 1 1 1 2 2 2 2 Perilipin family Apolipoprotein PF01442.13 EAU84786.1 - 1.2e-06 28.2 6.8 0.00018 21.1 3.0 2.4 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain HN PF00423.14 EAU84786.1 - 0.0015 16.8 1.3 0.0015 16.8 0.9 1.6 2 0 0 2 2 2 1 Haemagglutinin-neuraminidase DUF883 PF05957.8 EAU84786.1 - 0.037 14.4 2.3 23 5.4 0.0 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.6 EAU84786.1 - 0.053 11.0 2.9 0.11 9.9 2.0 1.6 1 0 0 1 1 1 0 Prominin Baculo_PEP_C PF04513.7 EAU84786.1 - 0.07 12.9 14.8 2.9 7.6 5.6 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIP3 PF03915.8 EAU84786.1 - 0.08 11.8 7.8 0.1 11.4 4.8 1.5 1 1 0 1 1 1 0 Actin interacting protein 3 DUF29 PF01724.11 EAU84786.1 - 0.29 10.9 4.8 0.21 11.4 1.7 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF29 Baculo_p24 PF05073.7 EAU84786.1 - 0.34 10.4 4.3 0.55 9.7 2.0 2.0 2 0 0 2 2 2 0 Baculovirus P24 capsid protein DUF1640 PF07798.6 EAU84786.1 - 0.74 9.8 6.7 0.48 10.4 3.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Polysacc_deac_1 PF01522.16 EAU84787.1 - 3.2e-20 71.9 0.0 5.8e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase AAA PF00004.24 EAU84789.2 - 6.7e-06 26.3 1.9 6.4e-05 23.1 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EAU84789.2 - 0.0055 16.4 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 EAU84789.2 - 0.0076 14.9 0.1 1.2 7.7 0.0 3.1 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 EAU84789.2 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAU84789.2 - 0.019 14.9 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EAU84789.2 - 0.026 13.9 0.2 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU84789.2 - 0.041 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAU84789.2 - 0.055 14.2 0.9 0.26 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EAU84789.2 - 0.077 12.0 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EAU84789.2 - 0.079 11.6 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_22 PF13401.1 EAU84789.2 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_L7Ae PF01248.21 EAU84790.2 - 1e-13 50.6 0.1 2.3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RFX_DNA_binding PF02257.10 EAU84792.2 - 3.8e-26 91.0 0.0 8.8e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Sigma70_ner PF04546.8 EAU84792.2 - 0.36 10.4 4.0 2.1 7.9 2.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DEAD PF00270.24 EAU84793.2 - 6.2e-38 129.9 0.0 2.3e-37 128.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EAU84793.2 - 9.9e-23 79.4 0.1 1.9e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EAU84793.2 - 6.3e-19 67.6 0.0 1.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU84793.2 - 0.00015 21.6 0.1 0.00054 19.8 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU84793.2 - 0.03 14.4 0.2 0.26 11.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EAU84793.2 - 0.14 11.3 3.6 0.44 9.8 0.0 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF1682 PF07946.9 EAU84796.2 - 1.3e-59 201.6 0.1 1.6e-59 201.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2992 PF11208.3 EAU84796.2 - 3.8 7.4 17.9 5.2 6.9 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) G6PD_C PF02781.11 EAU84798.1 - 3.5e-122 406.8 0.0 5.2e-122 406.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EAU84798.1 - 1.8e-63 214.0 0.0 2.6e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FimP PF09766.4 EAU84799.1 - 9.6e-31 107.1 13.6 1.2e-30 106.8 9.4 1.0 1 0 0 1 1 1 1 Fms-interacting protein Paf67 PF10255.4 EAU84799.1 - 0.069 12.0 1.5 0.086 11.7 1.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 DUF2935 PF11155.3 EAU84799.1 - 0.21 11.7 2.4 0.65 10.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF948 PF06103.6 EAU84799.1 - 0.22 11.3 3.8 7.4 6.5 0.6 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UQ_con PF00179.21 EAU84800.2 - 2.1e-38 130.8 0.1 2.9e-38 130.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.1 EAU84800.2 - 0.015 14.8 0.1 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family E DUF2262 PF10020.4 EAU84800.2 - 0.062 13.5 0.1 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Phage_tail_X PF05489.7 EAU84800.2 - 0.12 11.8 0.0 18 4.8 0.0 2.6 3 0 0 3 3 3 0 Phage Tail Protein X DUF3815 PF12821.2 EAU84801.2 - 0.013 15.4 0.8 0.02 14.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) Polysacc_synt_C PF14667.1 EAU84801.2 - 0.015 15.0 1.3 0.015 15.0 0.9 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain AzlD PF05437.7 EAU84801.2 - 0.36 10.8 3.8 1.4 8.8 2.6 1.8 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF2029 PF09594.5 EAU84801.2 - 0.47 9.9 6.4 1.5 8.2 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2029) SKG6 PF08693.5 EAU84801.2 - 2.7 7.3 6.8 3.5 7.0 0.1 2.9 3 0 0 3 3 3 0 Transmembrane alpha-helix domain MARVEL PF01284.18 EAU84802.1 - 1e-05 25.4 12.4 1.4e-05 24.9 8.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain Spore_YabQ PF09578.5 EAU84802.1 - 0.34 10.9 10.6 0.04 13.8 3.4 2.1 2 1 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) HlyIII PF03006.15 EAU84802.1 - 4.9 6.5 11.9 0.39 10.0 4.7 1.6 2 0 0 2 2 2 0 Haemolysin-III related Mucin PF01456.12 EAU84803.2 - 0.0045 16.7 0.5 0.012 15.4 0.1 1.8 2 0 0 2 2 2 1 Mucin-like glycoprotein ABC2_membrane_2 PF12679.2 EAU84803.2 - 0.028 13.2 7.5 0.043 12.6 5.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein MARVEL PF01284.18 EAU84803.2 - 0.12 12.2 14.4 5.3 6.8 10.5 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF4131 PF13567.1 EAU84803.2 - 0.2 11.0 5.4 21 4.4 3.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2127 PF09900.4 EAU84803.2 - 0.59 10.1 4.2 0.48 10.4 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2127) Tetraspannin PF00335.15 EAU84803.2 - 0.83 8.8 5.5 7.2 5.8 3.8 2.5 1 1 0 1 1 1 0 Tetraspanin family DUF1772 PF08592.6 EAU84803.2 - 0.99 9.1 0.0 0.99 9.1 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) AMP-binding PF00501.23 EAU84804.2 - 9.5e-40 136.2 0.0 1.3e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.20 EAU84806.2 - 3.8e-64 216.3 0.2 2.2e-42 145.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84806.2 - 1.4e-27 96.3 0.1 1.6e-20 73.3 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EAU84806.2 - 0.00016 20.7 0.0 0.00044 19.3 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU84806.2 - 0.00058 18.9 0.3 0.0016 17.4 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EAU84806.2 - 0.00095 18.9 0.1 0.024 14.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EAU84806.2 - 0.0038 17.7 1.7 0.007 16.8 0.7 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain RIO1 PF01163.17 EAU84806.2 - 0.0059 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 EAU84806.2 - 0.0061 15.3 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EAU84806.2 - 0.035 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 NUFIP1 PF10453.4 EAU84806.2 - 0.056 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Prefoldin_2 PF01920.15 EAU84807.1 - 3.2e-22 78.3 8.9 3.8e-22 78.0 6.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.10 EAU84807.1 - 0.0012 18.2 7.0 0.051 13.0 0.4 2.1 2 0 0 2 2 2 2 Septum formation initiator AAA_27 PF13514.1 EAU84807.1 - 0.02 12.6 6.6 0.024 12.3 4.6 1.0 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 EAU84807.1 - 0.022 14.4 3.4 1.8 8.3 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II Prefoldin PF02996.12 EAU84807.1 - 0.026 14.1 7.3 0.15 11.7 0.1 2.1 1 1 1 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.7 EAU84807.1 - 0.029 14.6 1.5 0.46 10.7 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.9 EAU84807.1 - 0.03 13.7 0.7 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Tox-URI2 PF15653.1 EAU84807.1 - 0.046 13.9 0.1 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 URI fold toxin 2 DUF948 PF06103.6 EAU84807.1 - 0.047 13.5 1.1 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EAU84807.1 - 0.058 13.5 3.9 0.095 12.8 2.7 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sed5p PF11416.3 EAU84807.1 - 0.093 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein Sed5p TBPIP PF07106.8 EAU84807.1 - 0.24 10.9 8.6 0.44 10.0 1.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nsp1_C PF05064.8 EAU84807.1 - 0.38 10.3 8.4 0.23 11.0 1.2 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region KfrA_N PF11740.3 EAU84807.1 - 0.42 11.0 5.0 1.1 9.7 3.4 1.7 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term FlxA PF14282.1 EAU84807.1 - 0.52 10.2 6.7 0.65 9.9 0.7 2.2 2 0 0 2 2 2 0 FlxA-like protein Seryl_tRNA_N PF02403.17 EAU84807.1 - 0.55 10.2 7.9 1.4 8.9 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 EAU84807.1 - 0.58 10.3 8.0 2.1 8.5 1.0 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 I_LWEQ PF01608.12 EAU84807.1 - 1.2 9.0 4.7 5.9 6.8 0.4 2.0 2 0 0 2 2 2 0 I/LWEQ domain DUF342 PF03961.8 EAU84807.1 - 1.4 7.2 4.4 1.8 6.9 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Matrilin_ccoil PF10393.4 EAU84807.1 - 1.4 8.3 5.8 2.4 7.5 0.3 2.5 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Remorin_C PF03763.8 EAU84807.1 - 1.4 8.4 5.4 1.2 8.6 0.5 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region TMF_DNA_bd PF12329.3 EAU84807.1 - 1.5 8.6 9.7 1.6 8.5 1.8 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EAU84807.1 - 1.5 8.6 13.4 0.62 9.9 1.3 2.2 2 0 0 2 2 2 0 Tropomyosin like Med4 PF10018.4 EAU84807.1 - 1.9 7.8 6.4 0.31 10.4 0.7 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 FlgN PF05130.7 EAU84807.1 - 2.1 8.5 7.6 3.9 7.7 5.3 1.4 1 1 0 1 1 1 0 FlgN protein NYD-SP28 PF14772.1 EAU84807.1 - 4.7 7.3 11.4 4.7 7.3 0.7 2.1 2 0 0 2 2 2 0 Sperm tail DUF4140 PF13600.1 EAU84807.1 - 4.9 7.6 6.9 15 6.0 0.5 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_23 PF13476.1 EAU84807.1 - 5 7.3 7.3 6.4 7.0 5.1 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.20 EAU84807.1 - 5.2 7.2 10.6 9 6.5 1.1 2.1 1 1 1 2 2 2 0 Syntaxin TPR_MLP1_2 PF07926.7 EAU84807.1 - 6.9 6.4 11.0 8.5 6.1 6.1 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.11 EAU84807.1 - 9.6 6.4 8.0 22 5.3 5.5 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 HypA PF01155.14 EAU84808.1 - 0.047 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TCTP PF00838.12 EAU84809.1 - 1.2e-66 223.7 1.5 1.4e-66 223.5 1.0 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein UTP15_C PF09384.5 EAU84810.1 - 1.4e-45 154.5 0.1 2.5e-45 153.8 0.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EAU84810.1 - 9.5e-31 104.5 0.3 1.3e-06 28.0 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EAU84810.1 - 0.0059 14.9 0.1 0.034 12.4 0.0 2.1 2 1 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 EAU84810.1 - 0.025 12.7 0.1 0.26 9.3 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CTNNBL PF08216.6 EAU84811.2 - 6.7e-28 96.4 1.6 8.5e-27 92.8 0.0 2.9 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.3 EAU84811.2 - 0.013 15.1 0.2 0.19 11.3 0.0 2.4 1 1 2 3 3 3 0 Myosin-binding striated muscle assembly central FAT PF02259.18 EAU84812.2 - 4.6e-66 223.2 2.8 1.5e-65 221.5 2.3 1.7 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EAU84812.2 - 1.7e-13 50.5 0.0 5.6e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_2 PF07719.12 EAU84812.2 - 6e-05 22.6 0.1 0.0038 17.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAU84812.2 - 0.00026 20.5 0.1 0.0029 17.2 0.1 2.7 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.1 EAU84812.2 - 0.00044 19.8 0.3 0.0077 15.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU84812.2 - 0.0024 17.4 0.1 0.036 13.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU84812.2 - 0.0037 17.1 0.3 1.3 9.0 0.1 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Asp PF00026.18 EAU84813.1 - 1.4e-113 379.3 0.1 1.7e-113 379.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAU84813.1 - 1.5e-09 38.0 0.0 2.8e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAU84813.1 - 4e-07 29.7 0.0 1.4e-05 24.7 0.0 2.7 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EAU84813.1 - 3.6e-05 24.1 0.1 0.049 14.1 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease BCDHK_Adom3 PF10436.4 EAU84818.1 - 2.7e-40 137.5 0.0 4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EAU84818.1 - 2.2e-13 49.8 0.0 9.7e-13 47.8 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EAU84818.1 - 0.047 13.4 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain PCI PF01399.22 EAU84822.1 - 9.5e-11 41.9 0.1 1e-09 38.6 0.0 2.5 3 0 0 3 3 3 1 PCI domain RPN7 PF10602.4 EAU84822.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 RdRP PF05183.7 EAU84823.2 - 3.6e-146 488.2 0.1 4.3e-146 487.9 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Spc97_Spc98 PF04130.8 EAU84824.2 - 7.6e-108 361.1 0.0 3.4e-105 352.4 0.0 3.1 2 1 0 2 2 2 2 Spc97 / Spc98 family Hairy_orange PF07527.8 EAU84824.2 - 0.14 11.8 1.5 2.2 8.1 0.0 3.4 3 0 0 3 3 3 0 Hairy Orange Thioredoxin PF00085.15 EAU84825.1 - 1.1e-60 201.7 0.9 7.2e-32 109.1 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EAU84825.1 - 1.5e-43 148.7 0.2 4.9e-33 114.4 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAU84825.1 - 3.4e-13 49.5 0.5 0.00038 20.5 0.0 3.9 3 1 1 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.1 EAU84825.1 - 3.9e-12 46.0 0.1 3.4e-05 23.7 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EAU84825.1 - 2.9e-11 43.5 2.5 0.0016 18.6 0.1 4.5 3 2 0 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.12 EAU84825.1 - 6.6e-07 28.4 0.2 1.2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 Calsequestrin AhpC-TSA PF00578.16 EAU84825.1 - 4.1e-06 26.5 0.8 0.061 13.0 0.0 3.1 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_4 PF13462.1 EAU84825.1 - 6.9e-05 22.9 0.7 0.22 11.5 0.0 3.4 3 1 1 4 4 4 2 Thioredoxin Redoxin PF08534.5 EAU84825.1 - 7.3e-05 22.3 2.5 0.22 11.0 0.0 3.1 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 EAU84825.1 - 0.061 13.1 0.2 0.87 9.4 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.19 EAU84825.1 - 0.34 10.9 2.9 4.3 7.4 0.0 3.0 2 1 0 2 2 2 0 Glutaredoxin RRM_1 PF00076.17 EAU84826.2 - 7.2e-14 51.1 0.0 1.4e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84826.2 - 1.6e-07 31.1 0.0 3.9e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18p PF00861.17 EAU84827.1 - 3.3e-43 146.6 0.2 1.2e-42 144.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EAU84827.1 - 6.6e-35 119.5 2.6 6.6e-35 119.5 1.8 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF2555 PF10742.4 EAU84827.1 - 0.1 12.2 0.3 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Med17 PF10156.4 EAU84828.2 - 2.2e-43 148.2 0.0 3.1e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.13 EAU84829.2 - 3.3e-17 62.2 0.1 5.5e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Snf7 PF03357.16 EAU84830.1 - 7.1e-31 106.8 24.6 7.1e-31 106.8 17.1 1.6 1 1 0 1 1 1 1 Snf7 DUF2428 PF10350.4 EAU84830.1 - 0.0035 16.4 0.4 0.0051 15.8 0.3 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) CheX PF13690.1 EAU84830.1 - 5.3 6.9 5.7 14 5.5 4.0 1.9 1 1 0 1 1 1 0 Chemotaxis phosphatase CheX DUF826 PF05696.6 EAU84830.1 - 6 7.0 8.1 0.89 9.7 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Iso_dh PF00180.15 EAU84831.1 - 6.7e-93 311.3 0.0 1.1e-92 310.6 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.14 EAU84832.1 - 4e-97 325.3 0.0 7.7e-97 324.4 0.0 1.5 1 0 0 1 1 1 1 RNB domain VID27 PF08553.5 EAU84835.1 - 8.5e-247 821.3 0.1 9.8e-247 821.1 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nuf2 PF03800.9 EAU84835.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Nuf2 family PI3K_p85B PF02192.11 EAU84835.1 - 0.068 12.6 0.5 0.16 11.3 0.3 1.6 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain DUF1282 PF06930.7 EAU84836.2 - 0.0083 15.8 0.5 0.0099 15.5 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Nop14 PF04147.7 EAU84839.1 - 0.093 10.6 8.3 0.13 10.1 5.7 1.2 1 0 0 1 1 1 0 Nop14-like family DnaJ PF00226.26 EAU84840.1 - 7.7e-19 67.1 0.0 1.3e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain RdRP PF05183.7 EAU84841.2 - 4.9e-143 477.8 0.0 6.2e-143 477.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Clat_adaptor_s PF01217.15 EAU84842.2 - 1.7e-56 189.8 1.3 2e-56 189.6 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF262 PF03235.9 EAU84845.2 - 3.6e-15 56.5 1.9 4e-15 56.4 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function DUF262 DUF4611 PF15387.1 EAU84845.2 - 0.64 10.2 6.1 8.7 6.5 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SR-25 PF10500.4 EAU84846.2 - 3.3 7.1 8.4 2.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TspO_MBR PF03073.10 EAU84847.1 - 3.1e-40 137.0 7.5 3.6e-40 136.8 5.2 1.0 1 0 0 1 1 1 1 TspO/MBR family Histidinol_dh PF00815.15 EAU84848.1 - 2.6e-175 582.9 1.4 5.1e-175 582.0 1.0 1.5 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EAU84848.1 - 1.3e-26 92.0 0.2 3.6e-26 90.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EAU84848.1 - 5e-07 29.9 1.2 1.1e-06 28.8 0.1 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Transket_pyr PF02779.19 EAU84849.1 - 8.7e-49 165.4 0.1 1.7e-48 164.4 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EAU84849.1 - 2e-40 137.6 0.1 5.6e-40 136.1 0.1 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain LLGL PF08366.8 EAU84849.1 - 0.14 12.0 0.0 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 LLGL2 adh_short PF00106.20 EAU84850.2 - 1.6e-33 115.9 0.0 2.6e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU84850.2 - 4.4e-17 62.3 1.2 4.9e-16 58.9 0.8 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU84850.2 - 3.1e-14 53.3 0.0 4.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAU84850.2 - 6.7e-08 32.7 0.0 1.1e-07 32.0 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAU84850.2 - 2.2e-06 27.2 0.1 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAU84850.2 - 0.00036 19.3 0.2 0.00076 18.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EAU84850.2 - 0.0015 17.8 0.1 0.2 10.8 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family Eno-Rase_NADH_b PF12242.3 EAU84850.2 - 0.059 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidohydro_2 PF04909.9 EAU84851.1 - 8.8e-32 110.7 0.0 1.1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_6 PF12697.2 EAU84852.2 - 5.5e-08 32.9 0.0 1.8e-07 31.3 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU84852.2 - 0.00088 19.0 0.0 0.0032 17.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU84852.2 - 0.11 11.6 0.0 0.69 9.0 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Iso_dh PF00180.15 EAU84853.2 - 3.5e-81 272.8 0.1 4.3e-81 272.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1504 PF07399.6 EAU84853.2 - 0.054 12.1 0.3 0.097 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1504) Piwi PF02171.12 EAU84854.2 - 6.2e-57 192.8 0.0 1.5e-42 145.6 0.0 2.3 2 0 0 2 2 2 2 Piwi domain DUF1785 PF08699.5 EAU84854.2 - 2e-16 59.0 0.0 5e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) CytoC_RC PF02276.13 EAU84854.2 - 0.082 12.0 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit SNARE_assoc PF09335.6 EAU84857.2 - 3.8e-17 62.6 1.6 3.8e-17 62.6 1.1 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein Ribosomal_L36e PF01158.13 EAU84858.1 - 1.5e-38 130.7 4.5 1.6e-38 130.5 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.2 EAU84858.1 - 0.051 12.9 0.2 0.064 12.6 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction INT_SG_DDX_CT_C PF15300.1 EAU84858.1 - 0.15 11.5 1.3 0.28 10.6 0.1 2.0 2 1 1 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus CK_II_beta PF01214.13 EAU84859.2 - 3.8e-79 264.4 0.0 5.2e-79 264.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.8 EAU84859.2 - 0.0021 17.7 9.5 0.0027 17.3 6.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.7 EAU84859.2 - 0.025 12.5 10.6 0.032 12.1 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EAU84859.2 - 0.11 11.7 13.4 0.16 11.2 9.3 1.1 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EAU84859.2 - 0.23 9.8 9.8 0.3 9.5 6.8 1.1 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 EAU84859.2 - 0.48 9.1 9.7 0.67 8.6 6.7 1.1 1 0 0 1 1 1 0 Paf1 BUD22 PF09073.5 EAU84859.2 - 0.62 9.0 6.9 0.87 8.5 4.8 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 EAU84859.2 - 2 6.3 9.3 2.7 5.9 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EAU84859.2 - 3.3 7.7 9.0 5.6 6.9 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RRN3 PF05327.6 EAU84859.2 - 4.9 5.1 7.6 6.6 4.7 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CRCB PF02537.10 EAU84860.2 - 2.2e-33 114.6 20.5 1.9e-20 72.8 5.2 2.3 2 0 0 2 2 2 2 CrcB-like protein DUF2203 PF09969.4 EAU84861.2 - 0.035 14.3 0.9 0.049 13.8 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HAD_2 PF13419.1 EAU84862.2 - 5.6e-21 75.5 0.5 9.7e-15 55.2 0.1 2.1 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Globin PF00042.17 EAU84862.2 - 0.0025 18.1 0.0 0.0053 17.0 0.0 1.5 1 0 0 1 1 1 1 Globin DUF2608 PF11019.3 EAU84862.2 - 0.023 13.7 0.0 3 6.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2608) Ribosomal_L6e PF01159.14 EAU84863.1 - 1.2e-37 128.3 0.2 2.3e-37 127.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EAU84863.1 - 3.3e-08 33.2 1.8 3.6e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain 60KD_IMP PF02096.15 EAU84864.2 - 7.3e-24 84.5 0.4 1.4e-23 83.6 0.3 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein Histone PF00125.19 EAU84865.2 - 3.7e-29 100.6 0.4 5.5e-29 100.1 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU84865.2 - 0.0081 16.3 0.2 0.013 15.6 0.2 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAU84865.2 - 0.017 15.1 0.7 0.05 13.6 0.5 1.8 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2833 PF11090.3 EAU84866.2 - 0.03 14.4 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) TRAM_LAG1_CLN8 PF03798.11 EAU84867.2 - 1.4e-31 109.6 27.3 1.4e-31 109.6 18.9 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EAU84867.2 - 5.5e-12 45.0 0.0 1.6e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 TRAM1-like protein RNase_T PF00929.19 EAU84868.2 - 3.1e-18 66.6 0.0 5.8e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.7 EAU84868.2 - 0.0079 16.4 3.2 0.0079 16.4 2.2 1.8 2 0 0 2 2 2 1 CHORD UPF0183 PF03676.9 EAU84869.1 - 1.5e-41 142.2 0.0 4e-41 140.9 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) DNA_pol_E_B PF04042.11 EAU84870.2 - 1.9e-43 148.1 0.7 1.9e-43 148.1 0.5 1.5 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Gly_transf_sug PF04488.10 EAU84871.2 - 1.7e-21 76.4 0.0 3.2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EAU84871.2 - 0.0021 16.6 2.8 0.13 10.6 0.4 2.1 1 1 1 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EAU84871.2 - 0.06 12.4 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein MFS_1 PF07690.11 EAU84872.2 - 1.6e-32 112.6 12.9 3.3e-32 111.5 8.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EAU84872.2 - 1.1e-07 30.5 5.5 4.5e-05 22.0 0.1 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EAU84872.2 - 9.5e-05 21.1 6.7 9.5e-05 21.1 4.6 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 EAU84872.2 - 0.0027 16.4 1.7 0.004 15.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TruD PF01142.13 EAU84873.1 - 1.7e-65 221.1 0.0 5.9e-64 216.0 0.0 2.6 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) GRP PF07172.6 EAU84873.1 - 5.2 7.6 14.5 2.2 8.7 0.6 2.7 2 0 0 2 2 2 0 Glycine rich protein family OMPdecase PF00215.19 EAU84874.2 - 5.7e-71 238.5 0.0 6.9e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family HWE_HK PF07536.9 EAU84874.2 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L6 PF00347.18 EAU84876.1 - 1.5e-28 99.1 5.2 7.4e-17 61.6 1.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 ICMT PF04140.9 EAU84877.1 - 4.9e-26 90.7 1.4 9e-26 89.9 0.9 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EAU84877.1 - 2.7e-12 46.7 2.3 2.7e-12 46.7 1.6 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 EAU84877.1 - 0.0024 17.2 4.3 0.0024 17.2 3.0 1.9 2 1 0 2 2 2 1 NnrU protein DUF354 PF04007.7 EAU84877.1 - 0.064 12.1 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF354) GTP_EFTU PF00009.22 EAU84878.2 - 9.1e-46 155.6 0.0 1.4e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAU84878.2 - 3.8e-16 58.7 0.0 6.8e-15 54.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EAU84878.2 - 5.7e-12 45.3 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EAU84878.2 - 2.2e-05 24.4 0.0 4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EAU84878.2 - 0.00022 21.2 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EAU84878.2 - 0.0016 18.9 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EAU84878.2 - 0.1 11.8 0.0 0.36 10.0 0.0 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit HMG14_17 PF01101.13 EAU84879.2 - 0.012 16.3 2.4 0.03 15.0 1.6 1.7 1 0 0 1 1 1 0 HMG14 and HMG17 Bravo_FIGEY PF13882.1 EAU84879.2 - 2 9.4 11.3 0.46 11.4 5.4 1.8 2 0 0 2 2 2 0 Bravo-like intracellular region ADH_N PF08240.7 EAU84880.1 - 1.5e-30 105.1 0.1 2.8e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU84880.1 - 9.9e-23 80.1 0.1 1.9e-22 79.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU84880.1 - 8.4e-07 29.9 0.0 1.9e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EAU84880.1 - 0.00018 22.0 0.1 0.00041 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU84880.1 - 0.02 15.3 0.0 0.056 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EAU84880.1 - 0.025 13.9 0.1 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_26 PF13659.1 EAU84880.1 - 0.078 13.0 0.1 0.51 10.3 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EAU84880.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.20 EAU84881.2 - 3.7e-46 157.3 0.0 4.6e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU84881.2 - 8e-21 74.2 0.0 1.1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU84881.2 - 0.00074 18.5 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU84881.2 - 0.032 13.2 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Meth_synt_2 PF01717.13 EAU84882.1 - 5.3e-141 469.2 0.0 1e-136 455.1 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EAU84882.1 - 2.2e-119 398.3 0.0 2.8e-107 358.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain ETF PF01012.16 EAU84882.1 - 0.091 12.4 3.9 1.2 8.8 1.0 2.5 1 1 1 2 2 2 0 Electron transfer flavoprotein domain Pox_A51 PF04948.8 EAU84882.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A51 protein eRF1_1 PF03463.10 EAU84885.2 - 6.6e-45 151.9 0.0 1.1e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EAU84885.2 - 7.2e-22 77.7 0.0 1.3e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EAU84885.2 - 1.3e-21 77.3 0.0 2.1e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Phosducin PF02114.11 EAU84886.1 - 0.0021 16.8 0.1 0.0027 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EAU84886.1 - 0.0029 17.2 0.1 0.0048 16.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin SLS PF14611.1 EAU84886.1 - 0.019 14.4 0.4 0.031 13.6 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Glyco_hydro_18 PF00704.23 EAU84887.2 - 6.4e-49 167.2 0.0 4.8e-40 138.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 HAP1_N PF04849.8 EAU84889.1 - 0.0086 15.0 1.7 0.014 14.3 1.2 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region SNARE PF05739.14 EAU84889.1 - 0.088 12.5 0.8 14 5.4 0.1 2.3 2 0 0 2 2 2 0 SNARE domain IncA PF04156.9 EAU84889.1 - 0.69 9.4 4.3 1.3 8.6 3.0 1.4 1 1 0 1 1 1 0 IncA protein Ank_2 PF12796.2 EAU84890.2 - 1e-13 51.3 0.0 4.1e-06 27.0 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU84890.2 - 2.6e-10 40.5 0.1 0.0021 18.5 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EAU84890.2 - 4.4e-10 38.8 0.0 3.5e-05 23.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EAU84890.2 - 1e-08 35.1 0.1 6.9e-06 26.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU84890.2 - 2.4e-06 27.2 0.1 0.016 15.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat MFS_1 PF07690.11 EAU84891.2 - 1.3e-13 50.4 12.7 1.6e-07 30.4 0.0 3.3 1 1 2 4 4 4 4 Major Facilitator Superfamily MFS_2 PF13347.1 EAU84891.2 - 2.9e-11 42.4 4.3 1.8e-10 39.8 1.7 2.4 2 1 1 3 3 3 1 MFS/sugar transport protein DUF202 PF02656.10 EAU84891.2 - 9 6.6 8.5 4.2 7.6 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF202) ATP_bind_4 PF01902.12 EAU84892.2 - 1.6e-34 119.1 0.0 3.1e-26 92.0 0.0 2.4 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EAU84892.2 - 2e-16 59.8 0.0 7.7e-09 35.3 0.0 3.3 3 1 0 3 3 3 2 Endoribonuclease L-PSP B3_4 PF03483.12 EAU84893.2 - 4.8e-27 94.5 0.0 8.6e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EAU84893.2 - 5.6e-19 67.7 0.0 5.8e-15 54.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF1212 PF06738.7 EAU84897.2 - 1.9e-34 118.7 2.3 1.9e-34 118.7 1.6 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EAU84897.2 - 4.3e-13 49.3 9.4 4.3e-13 49.3 6.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) tRNA-synt_2d PF01409.15 EAU84898.2 - 6.4e-85 284.2 0.0 7e-55 185.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EAU84898.2 - 0.00019 21.0 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EAU84898.2 - 0.00049 18.9 2.3 0.0037 16.0 0.0 3.0 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) Pex2_Pex12 PF04757.9 EAU84899.2 - 3.2e-36 124.9 7.9 4.3e-36 124.4 5.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.1 EAU84899.2 - 0.00013 21.6 2.7 0.00013 21.6 1.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EAU84899.2 - 0.00057 19.9 1.9 0.0011 19.0 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAU84899.2 - 0.002 17.7 3.8 0.0085 15.7 2.7 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU84899.2 - 0.0036 17.0 6.8 0.012 15.3 2.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAU84899.2 - 0.0041 17.1 4.8 0.0041 17.1 3.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU84899.2 - 0.0071 16.2 3.6 0.022 14.6 2.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAU84899.2 - 0.027 14.1 2.8 0.11 12.1 2.0 2.1 1 1 0 1 1 1 0 RING-type zinc-finger IBN_N PF03810.14 EAU84900.2 - 1.1e-05 25.2 0.6 0.0042 16.9 0.3 3.5 3 1 1 4 4 4 2 Importin-beta N-terminal domain Slx4 PF09494.5 EAU84901.1 - 2e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Mur_ligase_M PF08245.7 EAU84902.2 - 3.7e-08 33.6 0.3 8.3e-07 29.2 0.2 2.7 1 1 0 1 1 1 1 Mur ligase middle domain BRCT PF00533.21 EAU84903.2 - 5.7e-10 39.2 0.0 9.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Sec63 PF02889.11 EAU84905.2 - 3.8e-77 259.6 0.3 6.7e-77 258.7 0.2 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EAU84905.2 - 1.5e-39 135.2 0.1 5.2e-29 100.9 0.1 4.2 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EAU84905.2 - 1.1e-11 44.9 0.1 2.9e-08 33.7 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU84905.2 - 1.5e-06 28.4 1.7 0.058 13.5 0.2 3.5 4 1 0 4 4 3 2 AAA domain Helicase_C PF00271.26 EAU84905.2 - 1.6e-06 27.8 0.0 7.8e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.9 EAU84905.2 - 2.1e-05 24.2 0.0 0.0023 17.6 0.0 2.8 3 0 0 3 3 3 1 Helicase AAA_19 PF13245.1 EAU84905.2 - 0.00023 20.8 0.0 0.35 10.6 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain FtsK_SpoIIIE PF01580.13 EAU84905.2 - 0.00028 20.4 0.0 0.025 14.0 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 EAU84905.2 - 0.00041 19.9 0.0 0.097 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAU84905.2 - 0.00042 19.8 0.0 0.43 9.9 0.0 3.7 3 1 1 4 4 4 1 AAA-like domain AAA_25 PF13481.1 EAU84905.2 - 0.0015 18.0 0.0 1.4 8.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain SNF2_N PF00176.18 EAU84905.2 - 0.0021 16.9 0.3 0.0095 14.7 0.0 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain DUF87 PF01935.12 EAU84905.2 - 0.016 15.0 0.0 0.09 12.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_11 PF13086.1 EAU84905.2 - 0.032 13.7 0.1 4.2 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EAU84905.2 - 0.095 12.1 0.6 20 4.5 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.11 EAU84905.2 - 0.099 11.8 0.0 16 4.6 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.16 EAU84905.2 - 0.2 10.8 0.0 1 8.6 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Aminotran_1_2 PF00155.16 EAU84906.2 - 3.3e-61 207.2 0.0 3.6e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EAU84906.2 - 1.5e-07 30.7 0.0 2.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EAU84906.2 - 2.2e-06 26.2 0.0 4.7e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EAU84906.2 - 6e-06 25.6 0.0 8.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EAU84906.2 - 0.0052 15.5 0.0 0.052 12.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V NAD_binding_6 PF08030.7 EAU84907.2 - 3.6e-19 69.2 0.0 5.8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAU84907.2 - 4.2e-19 68.3 0.0 1.6e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EAU84907.2 - 2.2e-12 47.1 8.0 2.2e-12 47.1 5.5 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Peroxin-13_N PF04088.8 EAU84907.2 - 0.048 13.6 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Ank_5 PF13857.1 EAU84908.2 - 2.3e-30 103.9 1.9 2.2e-09 37.2 0.0 5.2 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU84908.2 - 2e-29 101.7 0.1 3.9e-19 68.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAU84908.2 - 2e-27 93.5 2.8 2.2e-06 27.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EAU84908.2 - 2.6e-27 94.6 0.9 4e-11 43.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU84908.2 - 7.7e-24 81.3 0.3 2.5e-05 24.0 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.16 EAU84908.2 - 3e-20 71.8 9.8 3e-20 71.8 6.8 1.9 2 0 0 2 2 1 1 FYVE zinc finger zf-RING_2 PF13639.1 EAU84908.2 - 9.3e-11 41.3 4.0 9.3e-11 41.3 2.8 4.1 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 EAU84908.2 - 0.00013 21.9 1.1 0.00013 21.9 0.7 2.5 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAU84908.2 - 0.00023 21.1 4.8 0.00023 21.1 3.3 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-DHHC PF01529.15 EAU84908.2 - 0.038 13.3 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase FANCL_C PF11793.3 EAU84908.2 - 0.061 13.2 6.7 0.033 14.1 2.2 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain DUF1843 PF08898.5 EAU84908.2 - 0.08 12.9 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) HypA PF01155.14 EAU84908.2 - 0.13 11.9 3.6 0.44 10.2 2.5 1.8 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 EAU84908.2 - 2.9 7.8 10.8 0.11 12.4 2.3 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.1 EAU84908.2 - 3.2 7.5 27.7 0.46 10.2 3.4 3.5 3 1 0 3 3 3 0 zinc-RING finger domain HAUS4 PF14735.1 EAU84909.1 - 0.0033 16.7 1.3 0.0046 16.3 0.9 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 eIF3g PF12353.3 EAU84909.1 - 0.07 13.0 0.6 0.11 12.3 0.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Lsr2 PF11774.3 EAU84909.1 - 0.18 11.7 2.7 0.4 10.6 1.9 1.6 1 0 0 1 1 1 0 Lsr2 Cwf_Cwc_15 PF04889.7 EAU84909.1 - 0.35 10.5 7.8 0.47 10.1 5.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PI31_Prot_N PF11566.3 EAU84910.1 - 2.5e-26 92.1 0.0 3.3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EAU84910.1 - 2.7e-10 40.7 15.6 2.7e-10 40.7 10.8 2.5 3 0 0 3 3 3 1 PI31 proteasome regulator DEAD PF00270.24 EAU84911.2 - 6.3e-47 159.2 0.0 2.3e-46 157.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU84911.2 - 1.6e-23 82.3 0.0 4.4e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EAU84911.2 - 0.014 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EAU84911.2 - 0.016 15.0 0.0 0.049 13.4 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Nsp1_C PF05064.8 EAU84912.1 - 1.1e-30 105.6 0.1 2.9e-30 104.3 0.1 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EAU84912.1 - 1.6e-18 67.0 121.2 3.2e-08 33.8 43.0 4.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region PspA_IM30 PF04012.7 EAU84912.1 - 0.22 10.8 3.3 6.7 6.0 0.6 2.2 2 0 0 2 2 2 0 PspA/IM30 family Lectin_N PF03954.9 EAU84912.1 - 0.28 10.5 2.6 11 5.4 0.1 2.8 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 EAU84912.1 - 0.32 10.8 5.8 0.96 9.2 0.4 2.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Dor1 PF04124.7 EAU84912.1 - 1.5 7.2 4.7 8.6 4.7 3.2 1.9 1 1 0 1 1 1 0 Dor1-like family NPV_P10 PF05531.7 EAU84912.1 - 1.7 8.9 3.9 61 3.9 0.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_10 PF12846.2 EAU84914.2 - 1.8e-09 37.4 0.3 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EAU84914.2 - 1.9e-05 24.1 0.5 0.0001 21.8 0.0 2.2 2 1 1 3 3 3 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EAU84914.2 - 0.00047 20.3 0.6 1 9.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EAU84914.2 - 0.031 13.7 0.1 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EAU84914.2 - 0.077 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EAU84914.2 - 0.13 11.1 0.1 0.69 8.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Methyltransf_8 PF05148.10 EAU84915.1 - 3.4e-67 226.3 0.0 7e-67 225.2 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EAU84915.1 - 2.4e-05 24.7 0.0 9.9e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU84915.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU84915.1 - 0.0095 15.5 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU84915.1 - 0.095 13.1 1.1 0.38 11.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain MIP-T3 PF10243.4 EAU84915.1 - 2.1 6.7 34.0 2.8 6.3 23.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPRTase PF14681.1 EAU84916.2 - 1.4e-67 226.9 0.0 1.6e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EAU84916.2 - 0.00068 19.3 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_1 PF00667.15 EAU84917.2 - 2.1e-52 177.7 0.0 3.4e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EAU84917.2 - 6.8e-10 39.4 0.0 2.2e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EAU84917.2 - 0.00017 21.5 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.19 EAU84917.2 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Transketolase_C PF02780.15 EAU84917.2 - 0.08 12.8 0.1 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Transketolase, C-terminal domain Glyco_hydro_9 PF00759.14 EAU84918.1 - 5.1e-94 315.6 8.2 9.9e-94 314.7 5.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 Dicer_dimer PF03368.9 EAU84918.1 - 0.088 12.5 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Dicer dimerisation domain GFO_IDH_MocA PF01408.17 EAU84919.1 - 4.2e-22 78.9 0.0 7.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAU84919.1 - 4.9e-08 32.7 0.0 8.9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EAU84919.1 - 0.0059 17.0 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EAU84919.1 - 0.031 14.5 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ubiquitin PF00240.18 EAU84920.2 - 2.5e-08 33.1 0.0 4.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EAU84920.2 - 0.069 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF1183 PF06682.7 EAU84920.2 - 0.23 11.0 2.5 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) cNMP_binding PF00027.24 EAU84921.1 - 4.8e-35 119.2 0.0 9.5e-18 63.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EAU84921.1 - 6.3e-10 38.3 0.1 1.7e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Mid2 PF04478.7 EAU84922.2 - 0.015 14.7 0.3 0.03 13.7 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2207 PF09972.4 EAU84922.2 - 0.036 12.6 0.0 0.049 12.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_gE PF02480.11 EAU84922.2 - 0.05 11.8 1.1 0.079 11.2 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.11 EAU84922.2 - 0.099 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF1049 PF06305.6 EAU84922.2 - 0.21 11.1 1.2 0.41 10.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) TMEM154 PF15102.1 EAU84922.2 - 2.7 7.7 10.9 92 2.7 7.6 2.3 1 1 0 1 1 1 0 TMEM154 protein family Ytp1 PF10355.4 EAU84923.1 - 7.8e-92 307.3 5.1 1.2e-91 306.7 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EAU84923.1 - 2.5e-16 59.1 0.3 2.5e-16 59.1 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) PGPGW PF09656.5 EAU84923.1 - 0.0099 15.1 0.2 0.0099 15.1 0.1 2.6 3 0 0 3 3 3 1 Putative transmembrane protein (PGPGW) DUF2306 PF10067.4 EAU84923.1 - 0.95 9.6 8.5 1.4 9.0 0.4 3.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2306) MbeD_MobD PF04899.7 EAU84925.2 - 0.022 14.6 1.9 0.4 10.6 0.1 2.5 1 1 1 2 2 2 0 MbeD/MobD like IncA PF04156.9 EAU84926.2 - 0.049 13.2 0.5 0.078 12.5 0.3 1.2 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 EAU84926.2 - 0.63 10.3 4.0 14 5.9 2.3 2.1 2 0 0 2 2 2 0 AAA domain FlxA PF14282.1 EAU84926.2 - 0.85 9.5 5.5 1.8 8.5 3.8 1.4 1 0 0 1 1 1 0 FlxA-like protein Pox_A_type_inc PF04508.7 EAU84926.2 - 1.6 8.7 4.5 2.6 8.0 0.1 3.0 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Nup160 PF11715.3 EAU84928.1 - 2e-38 131.8 0.1 4.7e-38 130.6 0.0 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Apc3 PF12895.2 EAU84928.1 - 0.0061 16.6 1.7 1.1 9.4 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EAU84928.1 - 0.0062 17.0 3.6 8.1 7.3 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU84928.1 - 0.0097 16.5 6.4 0.087 13.5 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU84928.1 - 0.028 14.7 3.0 0.71 10.2 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAU84928.1 - 0.056 13.2 1.3 1.3 8.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU84928.1 - 0.093 12.6 4.5 2.9 7.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU84928.1 - 0.11 12.4 6.8 6.2 6.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAU84928.1 - 0.12 12.2 3.8 46 4.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAU84928.1 - 0.27 10.8 2.7 8.3 6.1 0.0 3.6 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 EAU84928.1 - 0.37 10.4 2.1 22 4.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EAU84929.1 - 1.2e-17 63.6 0.8 2.1e-17 62.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU84929.1 - 2.6e-05 24.0 9.2 4.9e-05 23.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 EAU84930.1 - 4.4e-59 196.0 29.1 1.5e-17 62.9 0.6 6.5 5 1 2 7 7 6 6 TPR repeat TPR_1 PF00515.23 EAU84930.1 - 3.1e-44 146.8 24.9 2e-07 30.3 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EAU84930.1 - 2e-38 127.1 34.8 0.00011 21.7 0.1 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EAU84930.1 - 6e-26 90.2 18.1 3.3e-13 49.3 0.2 6.5 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAU84930.1 - 3.3e-25 88.1 16.4 2.8e-06 27.8 0.1 6.8 3 1 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EAU84930.1 - 1.4e-20 71.9 16.3 0.0061 17.0 0.1 9.5 5 2 5 10 10 9 6 Tetratricopeptide repeat TPR_17 PF13431.1 EAU84930.1 - 2.5e-18 64.6 3.6 0.077 13.2 0.0 7.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 EAU84930.1 - 3.1e-18 64.0 23.8 0.001 18.7 0.0 9.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EAU84930.1 - 6.1e-18 64.9 19.9 2.4e-08 34.2 0.0 7.7 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 EAU84930.1 - 1.3e-15 55.8 15.3 0.0006 19.4 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAU84930.1 - 3.5e-15 55.5 6.5 0.0073 16.1 0.0 6.4 5 2 2 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EAU84930.1 - 5.9e-10 39.1 9.5 2.6e-05 24.2 0.0 5.3 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EAU84930.1 - 2.1e-07 30.9 24.7 0.4 11.2 0.1 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_3 PF07720.7 EAU84930.1 - 0.00015 21.4 15.7 0.35 10.7 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EAU84930.1 - 0.00037 20.5 10.3 4.3 7.5 0.0 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAU84930.1 - 0.00054 19.7 4.4 2 8.4 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF357 PF04010.8 EAU84930.1 - 0.0078 15.8 0.4 0.0078 15.8 0.3 2.9 2 2 2 4 4 4 1 Protein of unknown function (DUF357) PPR PF01535.15 EAU84930.1 - 0.028 14.3 4.1 21 5.4 0.1 4.7 4 0 0 4 4 4 0 PPR repeat Alkyl_sulf_dimr PF14863.1 EAU84930.1 - 0.19 11.9 10.6 4.2 7.5 0.0 4.2 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation XPC-binding PF09280.6 EAU84930.1 - 0.21 11.0 13.7 1.6 8.2 2.8 2.8 2 0 0 2 2 2 0 XPC-binding domain SHNi-TPR PF10516.4 EAU84930.1 - 0.53 9.5 5.2 6.8 6.0 0.1 4.4 6 0 0 6 6 6 0 SHNi-TPR APG6 PF04111.7 EAU84932.1 - 0.081 11.9 23.5 0.12 11.4 16.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DBINO PF13892.1 EAU84932.1 - 0.2 11.6 28.3 0.28 11.2 19.6 1.2 1 0 0 1 1 1 0 DNA-binding domain Mgr1 PF08602.5 EAU84932.1 - 0.25 10.2 8.2 0.3 10.0 5.7 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF1154 PF06631.6 EAU84932.1 - 0.5 10.0 19.5 0.74 9.5 4.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) DDE_Tnp_IS66 PF03050.9 EAU84932.1 - 0.79 8.8 13.4 1 8.5 9.3 1.1 1 0 0 1 1 1 0 Transposase IS66 family CAF-1_p150 PF11600.3 EAU84932.1 - 1.4 8.2 31.4 1.8 7.9 21.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF342 PF03961.8 EAU84932.1 - 3.1 6.1 18.1 3.6 5.9 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SecD-TM1 PF13721.1 EAU84932.1 - 4 7.7 6.3 0.84 9.9 1.4 1.9 1 1 1 2 2 2 0 SecD export protein N-terminal TM region Borrelia_P83 PF05262.6 EAU84932.1 - 4.7 5.3 29.3 5.8 5.0 20.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Init_tRNA_PT PF04179.7 EAU84932.1 - 7.6 5.2 14.1 9.5 4.9 9.7 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase HSP70 PF00012.15 EAU84932.1 - 7.6 4.3 21.9 9.7 3.9 15.2 1.1 1 0 0 1 1 1 0 Hsp70 protein PEP-utilisers_N PF05524.8 EAU84932.1 - 7.7 6.3 15.8 97 2.7 11.0 2.1 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Isochorismatase PF00857.15 EAU84933.2 - 8.7e-11 42.0 0.4 0.00011 22.1 0.0 2.6 1 1 1 2 2 2 2 Isochorismatase family Cortex-I_coil PF09304.5 EAU84934.2 - 0.00092 19.2 15.2 0.00092 19.2 10.5 2.8 2 1 1 3 3 2 1 Cortexillin I, coiled coil AAA_23 PF13476.1 EAU84934.2 - 0.011 16.0 2.5 0.027 14.8 1.7 1.6 1 0 0 1 1 1 0 AAA domain CENP-F_N PF10481.4 EAU84934.2 - 0.014 14.8 10.7 0.011 15.0 5.1 2.3 2 0 0 2 2 2 0 Cenp-F N-terminal domain AAA_13 PF13166.1 EAU84934.2 - 0.11 10.8 4.1 0.17 10.3 2.8 1.2 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 EAU84934.2 - 0.13 11.4 13.5 0.25 10.5 9.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 EAU84934.2 - 0.22 11.0 12.6 5.5 6.5 6.1 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) THOC7 PF05615.8 EAU84934.2 - 0.8 9.9 12.6 23 5.2 0.0 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 APG6 PF04111.7 EAU84934.2 - 0.96 8.4 14.6 1.7 7.5 10.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 NPV_P10 PF05531.7 EAU84934.2 - 1.2 9.4 4.8 4.6 7.5 3.3 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EAU84934.2 - 1.2 9.2 6.0 1.2 9.3 2.9 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.4 EAU84934.2 - 1.2 7.4 6.8 2.8 6.2 4.7 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 EAU84934.2 - 1.6 8.2 22.8 1.7 8.2 13.9 2.4 1 1 1 2 2 2 0 IncA protein Cob_adeno_trans PF01923.13 EAU84934.2 - 1.8 8.3 5.1 1.7 8.4 2.3 1.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase ADIP PF11559.3 EAU84934.2 - 2.3 8.1 17.0 6.1 6.7 9.1 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EAU84934.2 - 4.2 7.2 26.6 1 9.1 0.1 2.7 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.9 EAU84934.2 - 6 6.4 13.4 3.8 7.0 7.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 EAU84934.2 - 7.2 6.5 23.3 20 5.0 0.1 3.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 EAU84934.2 - 7.8 4.2 7.4 12 3.5 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.4 EAU84934.2 - 9.1 6.0 16.4 10 5.9 8.0 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain B12D PF06522.6 EAU84935.1 - 1.6e-11 43.7 0.1 2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.16 EAU84936.2 - 1.9e-42 145.0 0.0 2.3e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family A_deamin PF02137.13 EAU84936.2 - 1.7e-25 90.0 0.0 2.3e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2838 PF10998.3 EAU84937.1 - 4.6e-38 129.5 11.7 1.5e-37 127.8 8.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) GET2 PF08690.5 EAU84937.1 - 0.26 10.4 6.2 0.47 9.6 4.3 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1748 PF08520.5 EAU84938.2 - 9.7e-24 82.8 0.0 1.1e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coat_F PF07875.7 EAU84938.2 - 0.14 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Coat F domain DAD PF02109.11 EAU84939.1 - 2.1e-46 156.6 1.0 2.3e-46 156.4 0.7 1.0 1 0 0 1 1 1 1 DAD family Sod_Fe_C PF02777.13 EAU84940.1 - 2.2e-14 53.1 0.3 2.4e-06 27.3 0.0 2.9 3 0 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Hexokinase_2 PF03727.11 EAU84941.1 - 6e-66 222.1 0.0 1.3e-41 142.4 0.0 2.2 1 1 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EAU84941.1 - 9.2e-64 214.5 0.0 1.5e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Mt_ATP-synt_D PF05873.7 EAU84942.1 - 6.7e-13 48.5 3.1 7.9e-13 48.3 2.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.4 EAU84942.1 - 0.0099 15.9 0.9 0.046 13.8 0.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2408) Cob_adeno_trans PF01923.13 EAU84942.1 - 0.01 15.6 0.2 0.013 15.2 0.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase OmpH PF03938.9 EAU84942.1 - 0.079 12.8 6.6 1.4 8.8 4.5 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_M75 PF09375.5 EAU84942.1 - 0.17 11.1 3.1 0.15 11.3 1.3 1.5 1 1 0 1 1 1 0 Imelysin bZIP_1 PF00170.16 EAU84943.1 - 7.4e-11 41.8 7.6 1.4e-10 40.9 5.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.3 EAU84943.1 - 7.6e-08 32.5 13.0 7.6e-08 32.5 9.0 3.2 3 1 0 3 3 3 1 Aft1 HRA domain bZIP_2 PF07716.10 EAU84943.1 - 3.1e-07 30.1 9.8 7.8e-07 28.8 6.8 1.8 1 0 0 1 1 1 1 Basic region leucine zipper Spt5_N PF11942.3 EAU84943.1 - 5.3 7.7 10.9 1 10.0 4.4 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3445 PF11927.3 EAU84944.1 - 1.6e-59 201.2 0.0 2.8e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) GDI PF00996.13 EAU84945.1 - 4.9e-54 183.3 0.0 7.4e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor RRM_1 PF00076.17 EAU84946.1 - 5.8e-42 141.1 0.0 5.4e-20 70.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU84946.1 - 2.9e-32 110.4 0.0 3.8e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU84946.1 - 7.2e-21 73.7 0.0 1.4e-09 37.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU84946.1 - 0.14 11.9 0.0 0.73 9.6 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ric8 PF10165.4 EAU84947.2 - 3.2e-70 237.1 0.0 4.9e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Corona_nucleoca PF00937.13 EAU84947.2 - 1.6 7.5 4.7 2.6 6.9 3.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med10 PF09748.4 EAU84948.1 - 7.7e-17 61.3 0.2 9.4e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.1 EAU84948.1 - 0.0029 17.6 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 PIN domain FAA_hydrolase_N PF09298.6 EAU84948.1 - 0.065 13.2 0.8 0.099 12.6 0.6 1.3 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal Herpes_UL35 PF04496.7 EAU84948.1 - 0.079 13.1 0.5 0.13 12.4 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL35 family Aconitase PF00330.15 EAU84950.1 - 2.4e-184 613.1 0.0 2.8e-184 612.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAU84950.1 - 8.4e-43 145.6 0.0 1.4e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF1237 PF06824.6 EAU84952.2 - 1.6e-136 455.2 0.1 1.9e-136 455.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Glyco_hydro_16 PF00722.16 EAU84955.2 - 0.0013 18.0 0.0 0.0038 16.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Prenyltransf PF01255.14 EAU84956.1 - 1.5e-78 263.0 0.0 1.8e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4426 PF14467.1 EAU84956.1 - 0.037 13.8 0.0 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) F-box-like PF12937.2 EAU84957.1 - 9.7e-05 22.0 0.3 0.00031 20.3 0.2 2.0 1 0 0 1 1 1 1 F-box-like DUF1411 PF07199.6 EAU84957.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) F-box-like PF12937.2 EAU84958.1 - 8e-12 44.6 0.1 2.2e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU84958.1 - 0.00019 20.9 0.0 0.00081 18.9 0.0 2.2 1 1 0 1 1 1 1 F-box domain Prefoldin_2 PF01920.15 EAU84958.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Prefoldin subunit DUF1192 PF06698.6 EAU84958.1 - 0.067 13.0 1.4 0.17 11.7 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Striatin PF08232.7 EAU84958.1 - 0.069 13.4 0.3 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 Striatin family LRR_8 PF13855.1 EAU84958.1 - 0.37 10.5 4.3 1.7 8.4 0.1 3.8 3 1 1 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EAU84959.1 - 2e-12 46.6 1.3 3.7e-12 45.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU84959.1 - 5.7e-05 22.6 0.1 0.00018 21.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EAU84959.1 - 0.00077 19.1 0.3 0.0017 18.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like domain Uricase PF01014.13 EAU84962.2 - 1.7e-54 183.6 3.3 2.1e-35 121.8 1.9 2.6 2 1 0 2 2 2 2 Uricase Cellulase PF00150.13 EAU84963.2 - 1.2e-20 73.8 3.4 2e-20 73.1 2.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Hydrophobin PF01185.13 EAU84964.1 - 6.1e-22 77.8 12.2 8.2e-22 77.4 8.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EAU84965.2 - 7.6e-22 77.5 12.6 1.1e-21 77.0 8.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin HSP33 PF01430.14 EAU84965.2 - 0.076 12.1 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein F-box-like PF12937.2 EAU84970.1 - 4.1e-08 32.8 0.7 1.7e-07 30.8 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU84970.1 - 0.00034 20.1 0.5 0.0014 18.2 0.4 2.2 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU84971.1 - 1.4e-06 27.9 3.0 1.7e-06 27.6 0.1 2.8 3 0 0 3 3 3 1 F-box-like Sec8_exocyst PF04048.9 EAU84971.1 - 0.006 16.2 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain F-box PF00646.28 EAU84971.1 - 0.02 14.5 1.1 0.02 14.5 0.8 2.8 3 0 0 3 3 3 0 F-box domain HrpB7 PF09486.5 EAU84971.1 - 0.025 14.4 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Phlebovirus_NSM PF07246.6 EAU84971.1 - 0.049 12.7 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M LRR_8 PF13855.1 EAU84971.1 - 0.79 9.5 3.0 1.6 8.5 0.0 2.9 3 1 0 3 3 3 0 Leucine rich repeat zf-MYND PF01753.13 EAU84972.2 - 2.5e-07 30.4 13.8 4.8e-07 29.5 9.6 1.4 1 0 0 1 1 1 1 MYND finger TEA PF01285.13 EAU84973.1 - 4.5e-10 39.2 1.3 7e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 TEA/ATTS domain family Cpn10 PF00166.16 EAU84974.1 - 7.9e-27 93.0 0.0 8.8e-27 92.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MFS_1 PF07690.11 EAU84975.2 - 3.9e-47 160.6 69.3 5.4e-40 137.1 37.7 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2648 PF10855.3 EAU84975.2 - 0.061 12.7 0.4 0.24 10.8 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) F-box-like PF12937.2 EAU84976.1 - 5.4e-06 26.0 0.8 5.4e-06 26.0 0.6 3.1 4 1 0 4 4 4 1 F-box-like F-box PF00646.28 EAU84976.1 - 0.0032 17.0 1.2 0.0032 17.0 0.8 3.4 3 1 0 3 3 3 1 F-box domain DUF745 PF05335.8 EAU84976.1 - 0.017 14.6 0.3 0.026 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Atg14 PF10186.4 EAU84976.1 - 0.023 13.6 0.5 0.037 12.9 0.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 EAU84976.1 - 0.025 13.9 0.4 0.043 13.2 0.3 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HR1 PF02185.11 EAU84976.1 - 0.046 13.4 0.4 0.096 12.4 0.2 1.5 1 0 0 1 1 1 0 Hr1 repeat CALCOCO1 PF07888.6 EAU84976.1 - 0.099 10.9 0.4 4 5.5 0.2 2.0 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FliJ PF02050.11 EAU84976.1 - 0.13 12.3 1.8 0.18 11.8 0.6 1.7 2 0 0 2 2 2 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 EAU84976.1 - 0.17 11.6 2.3 0.29 10.8 1.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 EAU84976.1 - 0.19 9.8 0.4 0.26 9.3 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA F-box-like PF12937.2 EAU84977.2 - 2.1e-10 40.1 0.5 4.3e-10 39.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU84977.2 - 9.1e-05 22.0 6.3 0.0019 17.8 4.3 2.6 1 1 0 1 1 1 1 F-box domain Spc7 PF08317.6 EAU84977.2 - 0.05 12.2 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AA_permease_2 PF13520.1 EAU84978.2 - 7.5e-36 123.5 13.9 6.2e-35 120.5 9.6 2.4 1 1 0 1 1 1 1 Amino acid permease dsrm PF00035.20 EAU84979.2 - 4.8e-05 23.8 0.2 7.2e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Double-stranded RNA binding motif HTH_Tnp_ISL3 PF13542.1 EAU84979.2 - 0.14 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF3808 PF10300.4 EAU84983.2 - 1.2e-78 264.8 0.0 3.7e-78 263.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EAU84983.2 - 0.00027 20.6 4.9 0.68 9.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU84983.2 - 0.00095 19.7 1.0 0.43 11.3 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU84983.2 - 0.0014 18.2 1.2 0.03 13.9 0.1 3.5 5 0 0 5 5 5 1 TPR repeat TPR_19 PF14559.1 EAU84983.2 - 0.0016 18.7 0.3 0.39 11.0 0.0 3.9 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU84983.2 - 0.009 15.9 1.9 16 5.5 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU84983.2 - 0.13 11.9 0.9 34 4.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EAU84983.2 - 0.14 12.3 0.9 1.6 8.8 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4250 PF14056.1 EAU84988.2 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) F-box-like PF12937.2 EAU84996.2 - 2.9e-05 23.6 0.0 5.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU84996.2 - 0.028 14.0 1.6 0.55 9.9 0.3 3.1 1 1 1 2 2 2 0 F-box domain PIF1 PF05970.9 EAU84997.2 - 6.8e-27 94.3 0.0 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAU84997.2 - 5.9e-09 35.9 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU84997.2 - 1.2e-07 31.4 0.0 2.7e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU84997.2 - 0.0013 18.4 0.0 0.0045 16.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain WD40 PF00400.27 EAU85001.1 - 8.9e-20 69.7 2.3 2.5e-11 43.0 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat RR_TM4-6 PF06459.7 EAU85003.2 - 8.4 6.2 6.8 16 5.2 4.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 EAU85004.2 - 0.19 10.8 4.9 0.56 9.3 3.4 1.8 1 0 0 1 1 1 0 Putative metallopeptidase domain Atrophin-1 PF03154.10 EAU85004.2 - 1 7.4 16.4 1.5 6.8 11.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family DDHD PF02862.12 EAU85004.2 - 7 6.3 8.1 0.45 10.2 0.7 2.2 2 1 0 2 2 2 0 DDHD domain WD40 PF00400.27 EAU85006.1 - 0.00093 19.0 0.2 0.12 12.3 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EAU85006.1 - 0.11 11.9 0.4 4.8 6.5 0.0 2.8 2 1 0 3 3 3 0 PQQ-like domain F-box-like PF12937.2 EAU85007.2 - 2.2e-09 36.8 0.1 8.8e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EAU85007.2 - 0.044 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 EAU85007.2 - 0.57 9.9 3.4 11 5.7 2.4 2.7 1 1 0 1 1 1 0 F-box domain Peptidase_C48 PF02902.14 EAU85008.2 - 3.3e-34 118.4 0.2 4.6e-34 117.9 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PROCN PF08083.6 EAU85009.2 - 2.1e-22 79.1 0.2 2.8e-22 78.7 0.1 1.0 1 0 0 1 1 1 1 PROCN (NUC071) domain POR PF01558.13 EAU85010.2 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Rick_17kDa_Anti PF05433.10 EAU85015.1 - 0.18 11.4 5.1 0.34 10.6 3.5 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EAU85015.1 - 0.68 9.6 6.0 1.3 8.6 4.2 1.4 1 0 0 1 1 1 0 Glycine zipper DUF605 PF04652.11 EAU85015.1 - 7.5 5.8 12.3 9.6 5.4 8.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF1049 PF06305.6 EAU85016.2 - 0.099 12.1 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF1191 PF06697.7 EAU85016.2 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Pho88 PF10032.4 EAU85017.1 - 9.2e-69 230.5 0.1 1e-68 230.3 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) PH PF00169.24 EAU85018.2 - 2.2e-05 24.6 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 PH domain TALPID3 PF15324.1 EAU85019.2 - 3.1 5.0 5.7 3.9 4.6 3.9 1.1 1 0 0 1 1 1 0 Hedgehog signalling target GST_N_2 PF13409.1 EAU85020.2 - 3.4e-21 75.0 0.0 5.9e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU85020.2 - 2.5e-14 52.8 0.0 5.7e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU85020.2 - 5.4e-09 35.9 0.0 9.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU85020.2 - 2.7e-06 27.7 0.0 4.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAU85020.2 - 0.00046 20.3 0.0 0.0058 16.8 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Aldedh PF00171.17 EAU85023.1 - 3.4e-72 243.2 0.0 4.2e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.13 EAU85023.1 - 0.014 16.0 0.0 0.1 13.3 0.0 2.4 2 0 0 2 2 2 0 Fic/DOC family BetR PF08667.5 EAU85023.1 - 0.18 11.7 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 BetR domain ATP-synt_G PF04718.10 EAU85024.1 - 4.3e-18 65.8 2.0 9.9e-18 64.6 0.2 2.1 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit HMG_box PF00505.14 EAU85025.2 - 7.3e-13 48.5 1.7 7.9e-13 48.4 0.2 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU85025.2 - 2.9e-05 24.3 0.2 6.5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain SAGA-Tad1 PF12767.2 EAU85025.2 - 0.43 10.2 2.6 1.2 8.6 1.8 1.6 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Complex1_LYR PF05347.10 EAU85028.1 - 4.5e-06 26.3 0.2 4.5e-06 26.3 0.1 2.5 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAU85028.1 - 4.4e-05 23.5 0.2 0.00015 21.8 0.1 1.9 1 0 0 1 1 1 1 Complex1_LYR-like DUF3461 PF11944.3 EAU85028.1 - 0.05 13.4 0.3 0.097 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) NapE PF06796.6 EAU85029.1 - 0.029 13.6 2.2 0.086 12.1 1.5 1.8 1 1 0 1 1 1 0 Periplasmic nitrate reductase protein NapE DUF912 PF06024.7 EAU85029.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RCR PF12273.3 EAU85029.1 - 0.33 11.5 1.9 2.6 8.5 0.2 2.3 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Ribonuc_L-PSP PF01042.16 EAU85030.2 - 1.7e-13 50.3 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP F-box-like PF12937.2 EAU85030.2 - 5.2e-05 22.8 2.9 0.00012 21.7 2.0 1.7 1 0 0 1 1 1 1 F-box-like TauD PF02668.11 EAU85034.2 - 2.6e-51 174.7 0.2 3.2e-51 174.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MULE PF10551.4 EAU85035.2 - 2.7e-09 37.0 0.0 8.2e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.10 EAU85035.2 - 3e-09 37.2 0.4 3e-09 37.2 0.3 2.2 2 0 0 2 2 2 1 FAR1 DNA-binding domain APOC4 PF15119.1 EAU85035.2 - 0.74 9.8 3.7 0.3 11.0 0.2 2.1 2 0 0 2 2 2 0 Apolipoprotein C4 PIF1 PF05970.9 EAU85037.2 - 1.6e-13 50.3 0.0 2.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAU85037.2 - 5.1e-10 39.3 0.0 1e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU85037.2 - 2e-07 30.7 0.0 3.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.4 EAU85037.2 - 0.0024 16.5 0.0 0.0039 15.8 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ArgK PF03308.11 EAU85037.2 - 0.093 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Zds_C PF08632.5 EAU85038.2 - 0.041 13.2 0.2 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2730 PF10805.3 EAU85038.2 - 0.048 13.4 0.3 2.5 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4472 PF14739.1 EAU85038.2 - 0.067 13.6 0.2 0.2 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Baculo_RING PF05883.6 EAU85038.2 - 0.076 12.8 0.0 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain CHDCT2 PF08074.6 EAU85039.2 - 0.081 12.6 0.2 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Pacifastin_I PF05375.8 EAU85039.2 - 0.24 10.9 2.2 14 5.3 0.1 2.3 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) IncA PF04156.9 EAU85041.1 - 0.084 12.4 4.2 0.2 11.2 2.9 1.6 1 0 0 1 1 1 0 IncA protein TTSSLRR PF12468.3 EAU85042.2 - 0.011 15.2 0.2 0.011 15.2 0.2 2.4 3 0 0 3 3 3 0 Type III secretion system leucine rich repeat protein NYD-SP12_N PF15015.1 EAU85047.1 - 0.078 11.1 0.0 0.099 10.8 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Aminotran_1_2 PF00155.16 EAU85048.2 - 0.11 11.4 0.0 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II PRANC PF09372.5 EAU85056.1 - 0.0004 20.2 0.2 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 PRANC domain F-box PF00646.28 EAU85056.1 - 0.00077 19.0 0.1 0.0016 18.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain 2-Hacid_dh_C PF02826.14 EAU85057.2 - 0.035 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box-like PF12937.2 EAU85062.2 - 1.4e-07 31.0 0.1 2.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85062.2 - 0.0096 15.5 0.2 0.033 13.8 0.2 2.0 1 1 0 1 1 1 1 F-box domain DUF1510 PF07423.6 EAU85064.1 - 6.6 6.0 14.4 11 5.2 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SH3_1 PF00018.23 EAU85065.2 - 3e-12 45.7 0.4 4.6e-12 45.1 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU85065.2 - 3.3e-12 45.7 0.2 5.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU85065.2 - 1.7e-09 37.0 0.0 2.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EAU85065.2 - 0.034 14.3 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Polysacc_deac_1 PF01522.16 EAU85066.2 - 5.4e-23 80.9 0.0 1.5e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase ATP_synt_I PF03899.10 EAU85067.1 - 0.0073 16.4 0.1 0.29 11.2 0.1 2.0 2 0 0 2 2 2 2 ATP synthase I chain F-box-like PF12937.2 EAU85068.2 - 0.00019 21.0 0.1 0.00036 20.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like Cellulase PF00150.13 EAU85069.2 - 2.3e-05 23.7 0.0 5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_6 PF01341.12 EAU85070.1 - 3.2e-88 295.9 1.6 4.4e-88 295.5 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 DUF1996 PF09362.5 EAU85071.2 - 3.8e-81 272.2 0.9 4.6e-81 271.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Esterase_phd PF10503.4 EAU85072.2 - 1.5e-19 70.0 0.1 2.6e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EAU85072.2 - 4.4e-13 48.6 5.0 4.4e-13 48.6 3.5 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EAU85072.2 - 4e-07 29.4 0.0 6.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAU85072.2 - 0.00033 20.4 0.1 0.00052 19.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU85072.2 - 0.0022 17.9 0.2 0.0081 16.0 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU85072.2 - 0.023 14.2 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EAU85072.2 - 0.025 14.1 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1996 PF09362.5 EAU85073.1 - 2.4e-83 279.3 0.2 3.1e-83 279.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU85073.1 - 1.5e-11 43.7 12.4 1.5e-11 43.7 8.6 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF1996 PF09362.5 EAU85074.1 - 1.4e-82 276.8 0.0 1.9e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU85074.1 - 1.3e-11 43.9 12.7 1.3e-11 43.9 8.8 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Pkinase PF00069.20 EAU85079.2 - 1.4e-65 221.0 0.0 3e-65 219.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85079.2 - 8.2e-39 133.2 0.0 1e-23 83.7 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EAU85079.2 - 3.9e-06 26.0 0.0 1e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAU85079.2 - 0.0013 18.5 14.4 0.0072 16.0 0.1 3.5 2 2 1 3 3 3 2 Phosphotransferase enzyme family Macscav_rec PF03523.8 EAU85079.2 - 0.039 13.6 0.4 0.1 12.3 0.3 1.7 1 0 0 1 1 1 0 Macrophage scavenger receptor Ferritin_2 PF13668.1 EAU85080.1 - 2.9e-34 117.9 0.4 4.4e-34 117.3 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyco_hydro_11 PF00457.12 EAU85081.1 - 1.4e-58 197.3 6.0 1.6e-58 197.0 4.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF3740 PF12548.3 EAU85081.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Sulfatase protein DUF1705 PF08019.7 EAU85084.2 - 0.026 14.0 0.1 0.037 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) OrfB_IS605 PF01385.14 EAU85084.2 - 0.14 11.5 0.1 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Probable transposase Ricin_B_lectin PF00652.17 EAU85085.2 - 2.3e-25 88.9 17.9 1.4e-14 54.2 1.6 1.9 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU85085.2 - 1.1e-09 38.5 0.8 9.9e-05 22.6 0.7 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like F-box-like PF12937.2 EAU85086.1 - 7.8e-08 31.9 0.5 2.1e-07 30.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like SlyX PF04102.7 EAU85086.1 - 0.3 11.4 3.5 0.89 9.9 2.4 1.7 1 0 0 1 1 1 0 SlyX FlxA PF14282.1 EAU85086.1 - 0.34 10.8 5.7 0.55 10.2 3.9 1.2 1 0 0 1 1 1 0 FlxA-like protein zf-C3HC4_2 PF13923.1 EAU85088.2 - 1.1e-06 28.5 5.5 1.8e-06 27.8 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU85088.2 - 2e-06 27.3 2.9 3e-06 26.7 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU85088.2 - 1.1e-05 25.1 3.3 1.8e-05 24.4 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAU85088.2 - 2.3e-05 23.9 6.0 3.7e-05 23.2 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU85088.2 - 4.6e-05 23.0 5.3 7.6e-05 22.3 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EAU85088.2 - 0.049 13.5 5.1 0.097 12.5 3.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAU85088.2 - 0.07 12.8 4.4 0.14 11.8 3.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger F-box-like PF12937.2 EAU85089.2 - 7.9e-09 35.1 0.1 1.6e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85089.2 - 0.082 12.5 1.0 0.41 10.3 0.1 2.3 2 0 0 2 2 2 0 F-box domain Pheromone PF08015.6 EAU85090.1 - 0.00037 21.2 7.0 0.0014 19.3 4.9 2.5 1 1 0 1 1 1 1 Fungal mating-type pheromone Hus1 PF04005.7 EAU85091.2 - 3.9e-60 203.2 0.0 4.4e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein UPF0086 PF01868.11 EAU85092.2 - 2.4e-20 71.9 0.0 9.1e-20 70.1 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function UPF0086 Med15 PF09606.5 EAU85092.2 - 1.9 6.5 7.7 3.4 5.7 5.3 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ricin_B_lectin PF00652.17 EAU85093.1 - 3.2e-23 82.1 10.8 3.2e-23 82.1 7.5 2.2 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU85093.1 - 2.9e-15 56.5 8.9 1e-09 38.6 6.5 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU85094.1 - 1.7e-20 73.3 4.1 1.7e-20 73.3 2.9 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU85094.1 - 2.5e-15 56.7 1.7 1.9e-09 37.8 1.4 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like DUF4360 PF14273.1 EAU85095.1 - 2.1e-29 102.5 0.2 2.4e-29 102.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Maf PF02545.9 EAU85097.1 - 5.6e-44 149.6 0.0 3.8e-27 94.6 0.0 2.1 2 0 0 2 2 2 2 Maf-like protein Cytochrom_B561 PF03188.11 EAU85098.2 - 0.031 14.1 2.1 0.11 12.2 1.4 1.9 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 DUF4396 PF14342.1 EAU85098.2 - 2.3 8.3 8.6 0.15 12.1 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Cation_ATPase_C PF00689.16 EAU85098.2 - 4 6.9 10.2 0.24 10.9 3.3 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus NUDIX PF00293.23 EAU85100.2 - 1.5e-15 57.0 0.1 2.3e-15 56.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain CAMSAP_CKK PF08683.6 EAU85100.2 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated F-box-like PF12937.2 EAU85101.1 - 1.6e-08 34.0 0.0 1.3e-07 31.2 0.0 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EAU85101.1 - 0.0035 16.9 2.0 4.2 7.1 0.0 3.6 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 EAU85102.1 - 3.2e-05 23.5 0.6 8.8e-05 22.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like ActA PF05058.7 EAU85102.1 - 1.5 6.7 8.1 2.3 6.1 5.6 1.2 1 0 0 1 1 1 0 ActA Protein F-box-like PF12937.2 EAU85104.1 - 2e-09 37.0 0.7 7.1e-09 35.2 0.5 2.1 1 1 0 1 1 1 1 F-box-like Aminotran_3 PF00202.16 EAU85105.2 - 2.2e-97 325.9 0.0 3e-96 322.2 0.0 2.2 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EAU85105.2 - 0.0062 15.5 0.0 0.012 14.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II F-box-like PF12937.2 EAU85106.2 - 7e-09 35.2 2.0 2.6e-08 33.4 1.4 2.1 1 0 0 1 1 1 1 F-box-like SlyX PF04102.7 EAU85106.2 - 0.1 12.9 0.2 0.33 11.3 0.1 1.8 1 0 0 1 1 1 0 SlyX RNB PF00773.14 EAU85106.2 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 RNB domain F-box-like PF12937.2 EAU85107.1 - 5.4e-07 29.2 0.8 5.4e-07 29.2 0.5 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU85107.1 - 0.0066 16.0 2.3 0.67 9.6 0.6 3.5 3 1 0 3 3 3 1 F-box domain FTH PF01827.22 EAU85107.1 - 0.034 13.7 0.3 0.1 12.1 0.1 1.8 1 1 0 1 1 1 0 FTH domain FliJ PF02050.11 EAU85107.1 - 0.054 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein Prominin PF05478.6 EAU85107.1 - 0.099 10.1 0.0 0.14 9.6 0.0 1.1 1 0 0 1 1 1 0 Prominin LigT_PEase PF02834.11 EAU85107.1 - 0.17 11.8 1.7 0.59 10.1 0.1 2.5 2 0 0 2 2 2 0 LigT like Phosphoesterase LRR_4 PF12799.2 EAU85107.1 - 1.3 8.7 3.8 11 5.7 0.6 2.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) CFEM PF05730.6 EAU85108.2 - 0.13 12.0 0.6 0.26 11.1 0.4 1.4 1 0 0 1 1 1 0 CFEM domain FAD_binding_3 PF01494.14 EAU85110.2 - 9.8e-16 57.7 0.0 1.6e-15 57.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAU85110.2 - 9.3e-11 41.2 1.6 4.2e-07 29.2 0.7 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU85110.2 - 1.4e-10 41.0 0.9 1.3e-08 34.6 0.1 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU85110.2 - 3.9e-08 33.4 0.0 2.6e-07 30.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU85110.2 - 1.2e-06 28.8 2.2 4.4e-06 27.0 0.1 2.8 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU85110.2 - 2.6e-06 26.5 0.2 4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EAU85110.2 - 1.5e-05 24.6 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EAU85110.2 - 3.5e-05 22.9 0.5 0.0074 15.2 0.1 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.9 EAU85110.2 - 5.7e-05 21.7 0.2 0.00044 18.8 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EAU85110.2 - 0.00028 20.1 0.1 0.0004 19.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EAU85110.2 - 0.00048 19.0 0.1 0.00085 18.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EAU85110.2 - 0.0022 16.6 1.2 0.044 12.4 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.19 EAU85110.2 - 0.0052 15.9 0.5 0.038 13.0 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EAU85110.2 - 0.014 14.5 0.1 0.027 13.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EAU85110.2 - 0.067 13.1 0.9 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain MIP-T3 PF10243.4 EAU85111.2 - 0.003 16.0 71.0 0.0044 15.5 24.8 2.2 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 Peroxidase_2 PF01328.12 EAU85113.1 - 8.1e-20 70.7 0.0 9.4e-20 70.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 RNase_P_Rpp14 PF01900.14 EAU85114.2 - 2e-10 40.5 0.0 1.8e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Rpp14/Pop5 family BBP1_C PF15272.1 EAU85115.1 - 0.0069 15.9 0.4 0.0069 15.9 0.3 1.5 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal DUF4472 PF14739.1 EAU85115.1 - 0.007 16.8 0.4 0.013 15.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) CALCOCO1 PF07888.6 EAU85115.1 - 0.036 12.3 0.3 0.048 11.9 0.2 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fmp27_WPPW PF10359.4 EAU85115.1 - 0.19 10.1 3.2 0.071 11.5 0.5 1.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain WD40_alt PF14077.1 EAU85115.1 - 1.8 8.2 9.3 0.093 12.3 1.2 2.5 2 1 1 3 3 3 0 Alternative WD40 repeat motif Aminotran_1_2 PF00155.16 EAU85117.2 - 9e-39 133.4 0.0 5e-38 130.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EAU85117.2 - 0.0005 18.4 0.0 0.00076 17.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme F-box-like PF12937.2 EAU85118.2 - 3.8e-08 32.9 2.7 4.4e-08 32.7 0.2 2.3 2 0 0 2 2 2 1 F-box-like AA_permease_2 PF13520.1 EAU85121.2 - 3.5e-86 289.3 40.9 4.4e-86 289.0 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAU85121.2 - 2.7e-17 62.2 28.4 2.7e-17 62.2 19.7 1.9 2 1 0 2 2 2 1 Amino acid permease DUF373 PF04123.8 EAU85121.2 - 6.8 5.6 8.0 0.72 8.8 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF4013 PF13197.1 EAU85122.2 - 0.0066 15.7 3.6 0.02 14.1 1.9 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF4013) F-box-like PF12937.2 EAU85123.2 - 2.4e-09 36.7 0.4 2.3e-08 33.6 0.0 2.7 2 0 0 2 2 2 1 F-box-like TPD52 PF04201.10 EAU85123.2 - 0.014 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Tumour protein D52 family F-box PF00646.28 EAU85123.2 - 0.06 13.0 2.8 0.13 11.9 0.5 2.8 3 1 0 3 3 3 0 F-box domain SPX PF03105.14 EAU85125.2 - 4.1e-40 138.2 1.3 6e-40 137.7 0.9 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EAU85125.2 - 3.8e-32 111.7 27.2 5.1e-32 111.3 18.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EAU85125.2 - 1.4e-15 56.7 22.3 8.8e-11 40.9 9.4 2.2 1 1 1 2 2 2 2 Citrate transporter Drc1-Sld2 PF11719.3 EAU85125.2 - 0.0085 15.2 0.2 0.013 14.5 0.2 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein PRP38_assoc PF12871.2 EAU85125.2 - 0.11 13.0 12.2 0.18 12.3 8.5 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Orn_Arg_deC_N PF02784.11 EAU85127.1 - 5.8e-72 241.8 0.0 8e-71 238.1 0.0 2.4 2 1 1 3 3 3 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EAU85127.1 - 1.9e-31 108.1 0.0 3.5e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Semialdhyde_dh PF01118.19 EAU85127.1 - 0.09 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PTPA PF03095.10 EAU85128.2 - 2.4e-96 322.4 0.0 2.8e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ku PF02735.11 EAU85129.2 - 1.8e-17 63.3 0.0 1.7e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EAU85129.2 - 6.9e-10 38.7 0.0 2.1e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 EAU85129.2 - 9e-09 34.6 0.3 2.1e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 EAU85129.2 - 0.00062 20.2 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 EAU85129.2 - 0.0028 17.8 0.0 0.0074 16.4 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Ish1 PF10281.4 EAU85129.2 - 0.015 15.4 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein VWA PF00092.23 EAU85129.2 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 von Willebrand factor type A domain Glutaredoxin PF00462.19 EAU85130.1 - 1.3e-18 66.6 0.0 1.2e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EAU85130.1 - 3e-14 52.5 0.0 9.2e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin HyaE PF07449.6 EAU85130.1 - 0.00012 21.9 0.0 0.13 12.1 0.0 2.5 2 1 0 2 2 2 2 Hydrogenase-1 expression protein HyaE GST_N_3 PF13417.1 EAU85130.1 - 0.00051 20.2 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_8 PF13905.1 EAU85130.1 - 0.00076 19.5 0.1 0.34 11.0 0.0 2.9 2 2 1 3 3 3 2 Thioredoxin-like ArsC PF03960.10 EAU85130.1 - 0.0046 17.0 0.0 0.025 14.6 0.0 2.1 2 1 0 2 2 2 1 ArsC family Phosducin PF02114.11 EAU85130.1 - 0.015 14.0 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosducin Pedibin PF08182.6 EAU85130.1 - 0.03 13.7 0.5 0.085 12.3 0.3 1.8 1 0 0 1 1 1 0 Pedibin/Hym-346 family SH3BGR PF04908.10 EAU85130.1 - 0.041 13.8 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_3 PF13192.1 EAU85130.1 - 0.069 12.9 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain zf-MYND PF01753.13 EAU85132.1 - 8.1e-10 38.4 8.7 1.5e-09 37.5 6.0 1.4 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.1 EAU85132.1 - 0.0016 18.9 0.0 1.8 9.1 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU85132.1 - 0.0071 16.5 0.0 14 6.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU85132.1 - 0.062 13.6 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF3552 PF12072.3 EAU85134.1 - 0.0039 16.4 47.7 1.1 8.4 10.8 3.4 1 1 2 3 3 3 3 Domain of unknown function (DUF3552) SAM_PNT PF02198.11 EAU85134.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain GAGA_bind PF06217.7 EAU85134.1 - 1.9 8.3 13.5 0.94 9.3 4.2 2.6 1 1 0 2 2 2 0 GAGA binding protein-like family Lge1 PF11488.3 EAU85134.1 - 6 7.1 32.6 3 8.1 6.6 4.1 2 1 1 4 4 4 0 Transcriptional regulatory protein LGE1 Tet_JBP PF12851.2 EAU85137.2 - 1.3e-13 50.6 0.0 1.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Baculo_PEP_C PF04513.7 EAU85140.2 - 0.0065 16.2 0.8 1.6 8.5 0.0 3.2 2 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.7 EAU85140.2 - 0.0091 14.2 0.1 0.018 13.2 0.0 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Phage_HK97_TLTM PF06120.6 EAU85140.2 - 0.037 13.3 0.7 0.07 12.4 0.5 1.5 1 0 0 1 1 1 0 Tail length tape measure protein BAR PF03114.13 EAU85140.2 - 0.042 13.3 0.4 2.5 7.5 0.1 2.2 1 1 1 2 2 2 0 BAR domain AAA_13 PF13166.1 EAU85140.2 - 0.11 10.8 0.7 5.7 5.2 0.1 2.1 1 1 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 EAU85140.2 - 0.18 10.9 1.3 0.28 10.3 0.1 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF445 PF04286.7 EAU85140.2 - 0.33 10.4 4.2 0.55 9.7 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Laminin_II PF06009.7 EAU85140.2 - 0.6 9.8 3.7 1.7 8.4 0.1 2.7 2 1 1 3 3 3 0 Laminin Domain II F-box-like PF12937.2 EAU85141.1 - 0.00023 20.8 0.5 0.00057 19.5 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85141.1 - 0.29 10.8 2.1 1.8 8.2 1.5 2.4 1 1 0 1 1 1 0 F-box domain Prenyltransf PF01255.14 EAU85142.1 - 3.6e-80 268.2 0.0 4.6e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4426 PF14467.1 EAU85142.1 - 0.024 14.4 0.1 0.056 13.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) SHP PF03579.8 EAU85142.1 - 0.11 11.8 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 Small hydrophobic protein Peptidase_S64 PF08192.6 EAU85144.1 - 0.066 11.5 0.4 0.13 10.5 0.1 1.4 1 1 0 1 1 1 0 Peptidase family S64 DUF31 PF01732.11 EAU85144.1 - 3.5 6.8 7.1 4.2 6.5 1.6 2.6 1 1 0 2 2 2 0 Putative peptidase (DUF31) Phage_connect_1 PF05135.8 EAU85149.2 - 0.08 13.1 0.6 0.23 11.6 0.1 2.1 2 1 0 2 2 2 0 Phage gp6-like head-tail connector protein IGFL PF14653.1 EAU85150.1 - 0.068 13.2 0.2 0.087 12.8 0.1 1.1 1 0 0 1 1 1 0 Insulin growth factor-like family MFS_1 PF07690.11 EAU85151.2 - 1.7e-33 115.8 22.6 1.7e-33 115.8 15.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAU85151.2 - 0.0024 16.1 0.5 0.0024 16.1 0.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2919 PF11143.3 EAU85151.2 - 0.04 13.7 0.8 0.04 13.7 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) Pyr_redox_3 PF13738.1 EAU85152.2 - 3.8e-16 59.7 0.1 1.7e-06 28.2 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAU85152.2 - 5.7e-14 51.2 0.1 3e-08 32.3 0.0 2.9 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EAU85152.2 - 1.5e-09 38.0 0.0 2e-06 27.8 0.0 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAU85152.2 - 5.2e-09 35.4 0.1 7.6e-06 25.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAU85152.2 - 0.00014 21.7 0.6 0.00036 20.5 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAU85152.2 - 0.00026 20.7 0.1 0.14 11.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EAU85152.2 - 0.0022 16.9 1.8 0.056 12.3 0.1 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU85152.2 - 0.0036 16.4 0.1 0.0066 15.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EAU85152.2 - 0.01 14.7 0.3 0.018 13.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EAU85152.2 - 0.029 14.7 0.0 0.22 11.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAU85152.2 - 0.031 13.1 0.7 0.15 10.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 EAU85152.2 - 0.082 12.0 0.0 0.32 10.1 0.0 1.9 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EAU85152.2 - 0.089 12.8 0.0 2.4 8.2 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EAU85152.2 - 0.12 11.8 0.1 7.5 5.9 0.0 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EAU85152.2 - 0.18 11.7 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain IF2_N PF04760.10 EAU85152.2 - 0.21 11.2 0.3 23 4.7 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region CoaE PF01121.15 EAU85154.1 - 1.7e-62 210.0 0.0 2.1e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EAU85154.1 - 8.2e-07 29.8 0.0 3.7e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU85154.1 - 6.1e-06 26.5 0.1 1.5e-05 25.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain Phytochelatin_C PF09328.5 EAU85154.1 - 0.0046 16.4 0.0 0.0059 16.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1984) AAA_33 PF13671.1 EAU85154.1 - 0.0098 15.7 0.2 0.28 11.0 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAU85154.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EAU85154.1 - 0.18 11.3 0.5 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ebola_NP PF05505.7 EAU85156.2 - 1.1 7.2 3.6 1.8 6.5 2.5 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein zf-C2H2_4 PF13894.1 EAU85157.1 - 0.003 17.7 1.8 0.33 11.3 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU85157.1 - 0.53 10.7 3.1 2.6 8.5 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type HgmA PF04209.8 EAU85158.2 - 1e-140 468.9 0.0 2.1e-140 467.9 0.0 1.4 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase Transketolase_N PF00456.16 EAU85159.2 - 5.5e-19 68.1 0.7 8.8e-18 64.1 0.5 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 EAU85159.2 - 3e-07 30.3 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EAU85159.2 - 3e-05 23.5 0.2 6e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 EAU85159.2 - 9.9e-05 21.9 0.1 0.00052 19.6 0.0 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EAU85159.2 - 0.0086 14.8 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF2603 PF10788.4 EAU85159.2 - 0.17 11.6 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) CCDC14 PF15254.1 EAU85163.2 - 0.52 8.6 0.9 0.81 7.9 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Cyanate_lyase PF02560.9 EAU85164.2 - 2.1e-34 116.8 0.0 3.3e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Complex1_LYR PF05347.10 EAU85165.2 - 7.1e-08 32.1 0.0 2.5e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAU85165.2 - 1.8e-06 28.0 0.0 7.4e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EAU85165.2 - 0.00034 21.0 0.2 0.00049 20.5 0.2 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Pkinase PF00069.20 EAU85167.2 - 1.6e-41 142.1 0.0 5.5e-41 140.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85167.2 - 1.1e-37 129.5 0.0 1.8e-37 128.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU85167.2 - 0.00013 21.0 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU85167.2 - 0.022 14.4 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.20 EAU85168.2 - 6.1e-57 192.9 0.0 9.4e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAU85168.2 - 8.5e-37 126.0 0.0 1.4e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EAU85168.2 - 0.00075 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EAU85168.2 - 0.032 14.2 0.0 0.097 12.7 0.0 1.8 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 EAU85168.2 - 0.038 12.9 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 Tubulin like DUF1479 PF07350.7 EAU85169.2 - 7.5e-112 373.8 0.0 9.2e-112 373.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EAU85169.2 - 0.0004 20.5 0.2 0.024 14.6 0.1 2.8 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 EAU85170.1 - 6.8e-38 130.2 23.0 1e-37 129.6 16.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Enkurin PF13864.1 EAU85170.1 - 0.36 11.0 1.2 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 Calmodulin-binding DUF1996 PF09362.5 EAU85171.2 - 2.7e-65 220.3 0.3 3.6e-65 219.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Pkinase PF00069.20 EAU85172.2 - 9.9e-28 96.9 0.0 2.1e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85172.2 - 1.5e-08 34.0 0.1 0.00048 19.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EAU85172.2 - 0.0055 16.0 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 EAU85172.2 - 0.0062 15.3 0.0 0.0085 14.9 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EAU85172.2 - 0.045 13.4 0.0 0.18 11.4 0.0 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L30 PF00327.15 EAU85175.2 - 9.5e-11 41.1 0.1 1.4e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DEAD PF00270.24 EAU85177.2 - 9.9e-13 47.9 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU85177.2 - 2.1e-08 33.8 0.4 5.3e-07 29.4 0.3 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU85177.2 - 0.00021 21.2 0.0 0.00066 19.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MAGE_N PF12440.3 EAU85177.2 - 1 9.6 7.0 2.1 8.6 4.9 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal F-box-like PF12937.2 EAU85179.2 - 0.0001 21.9 0.0 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85179.2 - 0.0054 16.3 0.0 0.021 14.4 0.0 2.1 1 0 0 1 1 1 1 F-box domain Abhydrolase_6 PF12697.2 EAU85180.1 - 0.0035 17.2 0.1 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU85180.1 - 0.046 13.2 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sdh_cyt PF01127.17 EAU85181.2 - 1.8e-25 89.0 0.8 2.4e-25 88.7 0.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PPTA PF01239.17 EAU85181.2 - 0.046 13.0 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat DUF1777 PF08648.7 EAU85185.1 - 0.2 11.3 16.1 0.3 10.8 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF572 PF04502.8 EAU85185.1 - 0.27 10.3 15.9 0.37 9.9 11.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.10 EAU85185.1 - 0.53 9.4 8.2 0.67 9.0 5.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 EAU85185.1 - 1.2 6.8 10.7 1.6 6.5 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.7 EAU85185.1 - 3.1 7.6 13.5 4.3 7.1 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF-1_p150 PF11600.3 EAU85185.1 - 3.3 7.0 32.8 5 6.4 22.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 EAU85185.1 - 4.5 6.2 18.9 12 4.7 13.2 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 OmpH PF03938.9 EAU85185.1 - 4.5 7.1 17.9 9.6 6.1 12.4 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ycf1 PF05758.7 EAU85185.1 - 4.9 4.7 11.7 6.4 4.3 8.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF2220 PF09983.4 EAU85185.1 - 6.3 5.9 11.7 11 5.1 8.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) F-box PF00646.28 EAU85187.1 - 1.6e-06 27.6 0.0 6.5e-06 25.6 0.0 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU85187.1 - 0.00024 20.7 0.1 0.00078 19.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like AJAP1_PANP_C PF15298.1 EAU85188.1 - 6.4e-05 22.9 2.2 0.00021 21.2 1.5 1.8 1 0 0 1 1 1 1 AJAP1/PANP C-terminus FixQ PF05545.6 EAU85188.1 - 0.0049 16.4 0.2 0.0095 15.5 0.1 1.5 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Herpes_gE PF02480.11 EAU85188.1 - 0.23 9.7 0.0 0.31 9.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E F-box-like PF12937.2 EAU85190.1 - 4.2e-06 26.3 0.3 1.4e-05 24.7 0.2 2.0 1 0 0 1 1 1 1 F-box-like Asp_protease_2 PF13650.1 EAU85191.2 - 0.0019 18.6 0.0 0.0055 17.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EAU85191.2 - 0.019 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ebola_NP PF05505.7 EAU85191.2 - 0.06 11.4 6.4 0.062 11.3 0.8 2.2 2 0 0 2 2 2 0 Ebola nucleoprotein LRR_4 PF12799.2 EAU85193.1 - 1.9e-05 24.1 1.1 0.0043 16.6 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAU85193.1 - 0.066 13.3 1.8 58 4.2 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.1 EAU85193.1 - 0.22 11.2 3.8 0.43 10.3 0.7 2.5 2 0 0 2 2 2 0 Leucine rich repeat AAA PF00004.24 EAU85195.2 - 2e-93 309.5 0.0 1.5e-46 157.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAU85195.2 - 1.1e-15 57.3 0.0 1.2e-08 34.3 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAU85195.2 - 8.9e-13 48.5 0.1 0.0035 17.4 0.0 5.4 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 EAU85195.2 - 1e-12 48.4 1.7 0.00022 21.2 0.0 4.5 3 2 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EAU85195.2 - 5e-12 46.6 0.0 7e-07 30.0 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAU85195.2 - 3.8e-11 43.0 0.0 5.5e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EAU85195.2 - 2.5e-10 40.2 0.4 0.0018 17.9 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EAU85195.2 - 5.3e-10 39.4 0.0 0.00064 19.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EAU85195.2 - 1.5e-09 37.7 0.0 0.00062 19.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EAU85195.2 - 1.8e-09 36.9 0.0 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EAU85195.2 - 1e-08 34.3 0.0 7.1e-05 21.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EAU85195.2 - 1.2e-07 31.3 1.3 0.0031 17.2 0.1 3.4 3 1 0 3 3 2 2 Part of AAA domain RNA_helicase PF00910.17 EAU85195.2 - 2.2e-07 31.0 0.0 0.02 15.0 0.0 2.8 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EAU85195.2 - 2.6e-07 30.2 0.0 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EAU85195.2 - 4e-07 29.4 0.2 0.024 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EAU85195.2 - 1.2e-06 28.5 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EAU85195.2 - 1.5e-06 27.9 0.4 0.087 12.4 0.0 3.8 3 1 1 4 4 4 2 NACHT domain AAA_3 PF07726.6 EAU85195.2 - 4.9e-06 26.1 0.0 0.0082 15.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EAU85195.2 - 1.7e-05 25.1 0.0 0.1 12.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 EAU85195.2 - 2.3e-05 23.8 7.0 0.65 9.3 0.0 4.6 3 2 2 5 5 4 1 AAA domain AAA_18 PF13238.1 EAU85195.2 - 2.5e-05 24.6 0.0 0.059 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EAU85195.2 - 2.5e-05 23.7 0.1 0.36 10.2 0.0 3.8 3 1 0 3 3 3 2 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EAU85195.2 - 0.00014 21.8 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family KaiC PF06745.8 EAU85195.2 - 0.00019 20.6 0.2 1.2 8.2 0.0 3.2 2 1 1 3 3 3 1 KaiC Sigma54_activ_2 PF14532.1 EAU85195.2 - 0.00022 21.2 0.0 0.66 10.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EAU85195.2 - 0.00029 20.4 0.0 0.46 9.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SKI PF01202.17 EAU85195.2 - 0.00031 20.6 0.0 0.82 9.5 0.0 2.4 2 0 0 2 2 2 2 Shikimate kinase NB-ARC PF00931.17 EAU85195.2 - 0.0004 19.3 0.1 0.69 8.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain PhoH PF02562.11 EAU85195.2 - 0.00083 18.6 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Rad17 PF03215.10 EAU85195.2 - 0.0017 17.1 0.0 0.32 9.6 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EAU85195.2 - 0.0019 17.9 0.0 4.4 6.9 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 EAU85195.2 - 0.002 17.0 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 EAU85195.2 - 0.0037 17.1 0.0 0.81 9.6 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATP-synt_ab PF00006.20 EAU85195.2 - 0.0048 16.4 0.0 1.4 8.3 0.0 2.9 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EAU85195.2 - 0.0051 15.7 0.0 0.2 10.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EAU85195.2 - 0.0084 15.7 0.0 0.79 9.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EAU85195.2 - 0.013 15.1 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EAU85195.2 - 0.016 14.6 0.0 4.8 6.5 0.0 3.3 3 1 0 3 3 3 0 AAA-like domain DUF2075 PF09848.4 EAU85195.2 - 0.019 13.9 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.13 EAU85195.2 - 0.02 14.5 0.0 5.4 6.5 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein AFG1_ATPase PF03969.11 EAU85195.2 - 0.022 13.6 0.1 3.2 6.4 0.0 2.4 2 1 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.1 EAU85195.2 - 0.023 14.2 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EAU85195.2 - 0.024 14.3 0.0 4.1 7.0 0.0 2.8 2 1 1 3 3 2 0 NTPase PduV-EutP PF10662.4 EAU85195.2 - 0.088 12.3 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EAU85195.2 - 0.11 11.4 0.0 3.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EAU85195.2 - 0.14 12.1 0.0 18 5.3 0.0 3.2 2 1 1 3 3 3 0 50S ribosome-binding GTPase ResIII PF04851.10 EAU85195.2 - 0.24 11.2 0.0 26 4.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MFS_1 PF07690.11 EAU85196.2 - 5.8e-19 68.0 24.3 1.4e-14 53.5 12.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DPM2 PF07297.7 EAU85196.2 - 0.054 13.7 1.3 0.12 12.6 0.1 2.2 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PepSY_TM_2 PF13703.1 EAU85196.2 - 1.9 8.6 6.5 3.3 7.9 0.0 3.2 4 0 0 4 4 4 0 PepSY-associated TM helix DUF1469 PF07332.6 EAU85196.2 - 6 6.6 8.8 3 7.6 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) HA2 PF04408.18 EAU85197.2 - 5.1e-26 90.6 0.0 9.9e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAU85197.2 - 4.7e-18 65.0 0.0 1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAU85197.2 - 3.1e-11 42.9 0.0 7.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU85197.2 - 1e-05 25.0 0.5 3.5e-05 23.3 0.4 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU85197.2 - 1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EAU85197.2 - 0.0025 17.2 0.5 0.017 14.5 0.1 2.5 3 1 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EAU85197.2 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU85197.2 - 0.016 15.1 0.1 0.091 12.7 0.0 2.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_14 PF13173.1 EAU85197.2 - 0.02 14.7 0.1 0.23 11.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAU85197.2 - 0.023 14.4 0.2 0.09 12.5 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain AAA_10 PF12846.2 EAU85197.2 - 0.025 14.0 0.1 14 5.0 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain ABC_tran PF00005.22 EAU85197.2 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.9 EAU85197.2 - 0.04 13.6 0.9 1.5 8.5 0.6 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EAU85197.2 - 0.048 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 EAU85197.2 - 0.095 11.5 0.0 0.22 10.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EAU85197.2 - 0.15 11.2 0.0 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 EAU85197.2 - 0.15 11.8 0.1 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.24 EAU85201.2 - 1.7e-17 63.4 0.0 2.8e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU85201.2 - 2.6e-17 62.4 0.0 4e-16 58.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU85201.2 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_polyA_pol PF03296.8 EAU85202.2 - 0.029 13.9 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain PRT_C PF08372.5 EAU85202.2 - 0.051 13.0 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Protoglobin PF11563.3 EAU85203.1 - 5.9e-39 133.2 0.8 7.5e-39 132.9 0.6 1.1 1 0 0 1 1 1 1 Protoglobin F-box-like PF12937.2 EAU85204.2 - 1.3e-14 53.6 0.2 3e-13 49.2 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU85205.1 - 4.5e-05 23.0 5.7 6.6e-05 22.5 0.4 3.2 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 EAU85208.1 - 1.5e-05 24.6 0.7 5.3e-05 22.8 0.5 2.0 1 0 0 1 1 1 1 F-box-like Cupin_2 PF07883.6 EAU85209.1 - 1.1e-29 101.6 0.9 6.8e-14 51.1 0.0 2.6 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.17 EAU85209.1 - 1.8e-28 98.8 0.0 9.7e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EAU85209.1 - 2e-10 39.8 0.0 0.00024 20.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EAU85209.1 - 2.4e-07 30.5 0.2 1.2e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EAU85209.1 - 2.9e-06 26.9 0.0 0.00041 19.9 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 EAU85209.1 - 9.1e-05 22.4 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family Cupin_4 PF08007.7 EAU85209.1 - 0.0039 16.4 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein 3-HAO PF06052.7 EAU85209.1 - 0.011 15.1 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.1 EAU85209.1 - 0.023 14.1 0.0 0.26 10.7 0.0 2.4 1 1 0 1 1 1 0 Cupin-like domain Tantalus PF15386.1 EAU85211.1 - 0.23 11.2 0.0 0.56 10.0 0.0 1.6 1 0 0 1 1 1 0 Drosophila Tantalus-like DUF829 PF05705.9 EAU85215.2 - 4.9e-26 91.8 0.0 8.3e-14 51.8 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic protein of unknown function (DUF829) Thg1C PF14413.1 EAU85216.2 - 1.9e-46 156.6 0.2 3.5e-45 152.5 0.1 2.2 1 1 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EAU85216.2 - 3.2e-20 72.1 0.0 5.5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF605 PF04652.11 EAU85216.2 - 0.00041 19.8 17.0 0.00046 19.6 11.8 1.1 1 0 0 1 1 1 1 Vta1 like XRCC4 PF06632.7 EAU85216.2 - 0.037 12.8 0.3 0.073 11.9 0.2 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cation_ATPase_C PF00689.16 EAU85216.2 - 0.05 13.1 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus PAT1 PF09770.4 EAU85216.2 - 2.1 6.4 10.0 2.7 6.1 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Menin PF05053.8 EAU85216.2 - 4.3 5.3 8.8 6.2 4.8 6.1 1.2 1 0 0 1 1 1 0 Menin Abhydrolase_6 PF12697.2 EAU85217.2 - 5.1e-25 88.6 0.1 8.5e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU85217.2 - 5.8e-08 32.5 0.0 1.3e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU85217.2 - 0.0013 18.3 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAU85217.2 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EAU85217.2 - 0.0091 16.2 0.0 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain SIR2 PF02146.12 EAU85218.2 - 1.8e-22 79.8 0.0 4.6e-09 36.2 0.0 3.4 2 2 0 2 2 2 2 Sir2 family AMP-binding PF00501.23 EAU85219.2 - 1.5e-82 277.2 0.6 5e-80 268.9 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EAU85219.2 - 9.7e-06 26.4 0.0 2.9e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cation_ATPase_C PF00689.16 EAU85219.2 - 0.08 12.4 8.9 0.22 11.0 6.1 1.8 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus CK_II_beta PF01214.13 EAU85220.2 - 3.5e-72 241.7 0.0 4.2e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CDK2AP PF09806.4 EAU85220.2 - 0.15 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PTCB-BRCT PF12738.2 EAU85222.2 - 6.9e-15 54.6 0.0 6.4e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EAU85222.2 - 1.3e-10 41.2 0.0 8.4e-05 22.6 0.0 3.7 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain Fork_head PF00250.13 EAU85223.1 - 5.7e-28 96.7 0.1 1e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Fork head domain Trypan_PARP PF05887.6 EAU85224.1 - 0.88 9.3 3.4 1.3 8.8 2.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DcpS_C PF11969.3 EAU85225.2 - 1.7e-11 44.3 0.2 2.2e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.2 EAU85228.2 - 0.00026 20.6 0.8 0.00054 19.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85228.2 - 0.0012 18.4 1.2 0.0012 18.4 0.8 2.1 2 0 0 2 2 2 1 F-box domain DUF4139 PF13598.1 EAU85229.1 - 1.7e-62 211.5 0.7 3.8e-61 207.1 0.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EAU85229.1 - 2.5e-16 60.0 1.4 2.5e-16 60.0 1.0 2.3 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 EAU85229.1 - 0.0002 21.5 14.0 0.0002 21.5 9.7 2.5 2 0 0 2 2 2 1 Nucleoporin FG repeat region IncA PF04156.9 EAU85229.1 - 0.085 12.4 0.8 0.13 11.8 0.5 1.2 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EAU85232.2 - 2.9e-15 55.8 46.0 1.3e-14 53.6 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PSDC PF12588.3 EAU85233.1 - 9e-37 125.8 0.0 1.8e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EAU85233.1 - 1.4e-33 115.9 0.0 2e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 EAU85233.1 - 0.0032 17.1 0.1 1.1 9.0 0.0 2.7 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain AMP-binding PF00501.23 EAU85234.1 - 5.6e-88 295.1 0.1 7.5e-88 294.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU85234.1 - 5.5e-06 27.2 0.0 1.3e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cation_ATPase_C PF00689.16 EAU85234.1 - 0.16 11.4 10.0 0.011 15.2 3.3 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Arrestin_N PF00339.24 EAU85235.1 - 0.0043 16.8 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EAU85235.1 - 0.017 15.2 0.0 0.17 12.0 0.0 2.6 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain COX6B PF02297.12 EAU85237.1 - 2.3e-20 72.3 4.7 3.4e-20 71.8 3.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EAU85237.1 - 0.00011 22.1 0.6 0.00015 21.6 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 GHL1-3 PF11308.3 EAU85237.1 - 0.0093 15.3 0.4 0.011 15.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 RINGv PF12906.2 EAU85237.1 - 0.023 14.7 0.1 0.023 14.7 0.0 1.8 2 1 0 2 2 2 0 RING-variant domain SR-25 PF10500.4 EAU85237.1 - 0.11 12.0 1.8 0.14 11.6 1.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RabGAP-TBC PF00566.13 EAU85238.2 - 8.7e-49 165.8 0.0 1.5e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain COPIIcoated_ERV PF07970.7 EAU85239.1 - 5.9e-38 130.7 1.5 9e-38 130.0 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EAU85239.1 - 2.4e-17 62.6 0.0 4.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) BTB PF00651.26 EAU85241.2 - 0.032 14.2 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Glyco_transf_28 PF03033.15 EAU85241.2 - 0.045 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_hydro_61 PF03443.9 EAU85243.2 - 1.2e-49 169.0 0.0 1.6e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAU85243.2 - 2.4 7.9 7.7 7.9 6.2 0.8 2.6 2 0 0 2 2 2 0 Fungal cellulose binding domain Abhydrolase_6 PF12697.2 EAU85244.2 - 3.3e-33 115.4 0.3 4.1e-33 115.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU85244.2 - 5.8e-20 71.8 0.0 9.5e-20 71.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU85244.2 - 9e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EAU85244.2 - 4.9e-10 40.0 0.0 7.3e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EAU85244.2 - 1.9e-07 30.9 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EAU85244.2 - 3.3e-05 23.2 0.0 5.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EAU85244.2 - 6.3e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 EAU85244.2 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF900 PF05990.7 EAU85244.2 - 0.0079 15.5 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.13 EAU85244.2 - 0.022 14.0 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) LCAT PF02450.10 EAU85244.2 - 0.03 13.2 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 EAU85244.2 - 0.041 13.4 0.0 0.079 12.5 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EAU85244.2 - 0.052 12.4 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EAU85244.2 - 0.059 12.1 0.0 0.093 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase VirJ PF06057.6 EAU85244.2 - 0.086 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Steroid_dh PF02544.11 EAU85246.1 - 2.4e-31 108.5 3.3 2.4e-31 108.5 2.3 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 EAU85246.1 - 2.7e-05 23.4 0.0 5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.7 EAU85246.1 - 0.068 12.4 0.7 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) COesterase PF00135.23 EAU85247.2 - 2.2e-88 297.3 0.0 1.9e-87 294.2 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU85247.2 - 4.2e-05 23.2 0.1 0.00017 21.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU85247.2 - 0.0099 15.1 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAU85248.2 - 2.9e-21 76.3 0.0 4.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU85248.2 - 1.7e-14 53.7 0.0 2.3e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EAU85248.2 - 1.7e-10 41.5 0.0 2.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EAU85248.2 - 6.8e-10 38.8 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EAU85248.2 - 1.5e-09 37.7 0.1 3.5e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 EAU85248.2 - 7.9e-07 28.5 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 EAU85248.2 - 9.7e-06 24.6 0.0 1.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EAU85248.2 - 6.6e-05 21.8 0.0 0.00014 20.8 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EAU85248.2 - 0.0003 20.5 0.0 0.00077 19.2 0.0 1.7 2 0 0 2 2 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EAU85248.2 - 0.00069 19.2 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EAU85248.2 - 0.0035 16.6 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EAU85248.2 - 0.0052 16.4 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EAU85248.2 - 0.032 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Integrase_AP2 PF14657.1 EAU85248.2 - 0.061 13.1 0.0 3.4 7.5 0.0 2.3 2 0 0 2 2 2 0 AP2-like DNA-binding integrase domain DUF915 PF06028.6 EAU85248.2 - 0.077 12.0 0.0 0.82 8.6 0.0 2.0 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 EAU85248.2 - 0.11 11.8 0.0 2.8 7.1 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Lipase_2 PF01674.13 EAU85248.2 - 0.15 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Bud13 PF09736.4 EAU85249.2 - 0.23 11.7 14.6 2.7 8.2 4.8 2.9 2 1 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Arv1 PF04161.8 EAU85250.2 - 1.4e-29 103.4 0.0 2.2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Arv1-like family zf-Sec23_Sec24 PF04810.10 EAU85250.2 - 0.11 12.1 4.2 0.16 11.5 0.0 2.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger SNARE_assoc PF09335.6 EAU85250.2 - 0.21 11.7 4.5 0.77 9.9 0.3 2.4 2 0 0 2 2 2 0 SNARE associated Golgi protein DUF410 PF04190.8 EAU85251.2 - 1.1e-25 90.7 0.0 1.3e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_16 PF13432.1 EAU85251.2 - 0.013 16.1 0.0 5.7 7.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat dsrm PF00035.20 EAU85253.1 - 4.9e-05 23.8 0.0 6.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif HSBP1 PF06825.7 EAU85255.1 - 7.9e-18 63.7 2.1 1.1e-17 63.3 1.4 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 ApoO PF09769.4 EAU85255.1 - 0.0038 16.9 0.1 0.0049 16.6 0.1 1.1 1 0 0 1 1 1 1 Apolipoprotein O Baculo_PEP_C PF04513.7 EAU85255.1 - 0.012 15.4 0.2 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.4 EAU85255.1 - 0.014 14.7 0.2 0.12 11.7 0.1 2.0 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF935 PF06074.7 EAU85255.1 - 0.036 12.8 0.3 0.042 12.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF4164 PF13747.1 EAU85255.1 - 0.049 13.7 0.2 0.067 13.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) GOLGA2L5 PF15070.1 EAU85255.1 - 0.054 11.9 0.0 0.057 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 HR1 PF02185.11 EAU85255.1 - 0.1 12.3 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Hr1 repeat Gti1_Pac2 PF09729.4 EAU85258.2 - 9.9e-48 162.1 0.1 2.8e-47 160.6 0.0 1.8 1 1 0 1 1 1 1 Gti1/Pac2 family Tfb2 PF03849.9 EAU85259.2 - 6.7e-106 354.0 0.0 1e-105 353.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EAU85259.2 - 0.00012 21.8 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank_2 PF12796.2 EAU85260.2 - 7.6e-48 160.7 1.3 1.5e-22 79.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAU85260.2 - 9.1e-48 157.7 4.0 1.2e-09 37.5 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EAU85260.2 - 2.3e-38 126.3 0.7 1.5e-06 27.8 0.0 6.1 5 1 1 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EAU85260.2 - 3e-37 126.3 1.5 8.5e-18 64.3 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU85260.2 - 1.6e-33 113.9 8.0 3.7e-12 46.0 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) DUF1996 PF09362.5 EAU85261.1 - 1.9e-74 250.2 0.2 2.5e-74 249.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) zf-RING_UBOX PF13445.1 EAU85262.2 - 0.29 10.8 1.8 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Terpene_synth_C PF03936.11 EAU85264.1 - 7.1e-15 54.9 0.0 9.2e-15 54.5 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EAU85264.1 - 0.00045 18.9 0.0 0.00061 18.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) RRM_6 PF14259.1 EAU85265.1 - 2e-06 27.6 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU85265.1 - 6.3e-05 22.5 0.0 9.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU85265.1 - 0.0036 17.1 0.0 0.0056 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRI PF15325.1 EAU85265.1 - 0.11 13.4 4.2 0.24 12.4 2.9 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection SPA PF08616.5 EAU85266.2 - 6e-08 32.3 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis COesterase PF00135.23 EAU85269.2 - 1.7e-97 327.3 0.0 2.6e-97 326.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU85269.2 - 2.5e-09 37.0 0.6 7.3e-09 35.5 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU85269.2 - 0.041 13.6 0.3 0.071 12.8 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU85269.2 - 0.059 12.5 0.3 0.099 11.8 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 EAU85270.2 - 1.3e-35 122.7 64.3 1.5e-30 106.1 23.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU85270.2 - 1.4e-11 43.6 23.8 2.5e-11 42.8 16.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAU85270.2 - 0.00026 19.3 0.6 0.00026 19.3 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EAU85271.2 - 8e-34 116.8 62.0 1.1e-30 106.5 21.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EAU85271.2 - 0.00092 17.5 0.7 0.0017 16.6 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Urease_alpha PF00449.15 EAU85273.2 - 1.9e-55 186.1 2.3 4.6e-55 184.9 1.6 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Amidohydro_1 PF01979.15 EAU85273.2 - 7.7e-54 183.5 2.4 1.1e-53 183.0 1.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_beta PF00699.15 EAU85273.2 - 4.8e-42 141.8 0.1 1.2e-41 140.5 0.1 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EAU85273.2 - 1.4e-38 130.8 0.0 4.6e-38 129.2 0.0 2.0 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EAU85273.2 - 2.2e-06 27.3 1.9 6.4e-06 25.9 1.3 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EAU85273.2 - 0.006 15.8 0.8 0.17 11.0 0.0 2.6 2 1 0 3 3 3 1 Amidohydrolase family Peptidase_C97 PF05903.9 EAU85275.2 - 0.0028 17.4 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EAU85275.2 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase RNase_PH PF01138.16 EAU85276.2 - 1.5e-07 31.7 7.6 0.0055 17.0 0.0 2.5 1 1 1 2 2 2 2 3' exoribonuclease family, domain 1 Vps39_1 PF10366.4 EAU85277.2 - 5.2e-26 90.7 1.2 2.1e-25 88.7 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EAU85277.2 - 3.1e-21 75.5 0.1 6.2e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EAU85277.2 - 3e-12 46.3 2.1 3.2e-10 39.7 0.2 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_4 PF07721.9 EAU85277.2 - 0.001 19.2 4.5 0.62 10.6 0.8 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU85277.2 - 0.0014 18.1 7.1 4.4 7.0 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU85277.2 - 0.0055 17.2 5.2 9.8 7.1 0.2 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU85277.2 - 0.0092 16.3 3.3 0.32 11.3 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU85277.2 - 0.029 14.3 8.8 4.8 7.1 0.2 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat CNH PF00780.17 EAU85277.2 - 0.034 13.5 0.0 0.11 11.9 0.0 1.8 2 1 0 2 2 2 0 CNH domain TPR_2 PF07719.12 EAU85277.2 - 0.035 14.0 8.7 8 6.6 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAU85277.2 - 0.048 13.4 4.7 28 4.8 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EAU85277.2 - 0.071 13.2 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.2 EAU85278.2 - 3.8e-28 97.6 0.8 1.5e-11 44.4 0.0 4.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU85278.2 - 6.3e-27 93.4 8.5 2.9e-09 37.1 0.1 6.9 5 3 2 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU85278.2 - 1.3e-23 82.5 7.6 5.6e-06 26.4 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EAU85278.2 - 5.8e-23 79.5 7.7 6.3e-08 32.0 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.1 EAU85278.2 - 1.3e-20 71.4 2.7 9.2e-05 22.3 0.0 8.4 8 0 0 8 8 8 4 Ankyrin repeat NTF2 PF02136.15 EAU85279.2 - 1.2e-08 35.3 0.0 0.0026 18.1 0.0 2.3 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain TAP_C PF03943.8 EAU85279.2 - 1e-06 28.0 0.1 2.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EAU85279.2 - 1.6e-06 27.5 4.9 5.3e-05 22.7 2.6 2.8 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EAU85279.2 - 0.00056 19.5 0.2 0.00095 18.7 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EAU85279.2 - 0.0063 16.4 1.4 15 6.0 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich repeat UBA_4 PF14555.1 EAU85279.2 - 0.027 13.9 0.5 0.068 12.7 0.3 1.7 1 0 0 1 1 1 0 UBA-like domain LRR_7 PF13504.1 EAU85279.2 - 0.21 11.8 3.2 45 4.9 0.4 4.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.28 EAU85279.2 - 1.2 9.4 3.5 4.4 7.7 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.1 EAU85279.2 - 1.3 8.8 6.1 4.6 7.0 4.3 2.0 1 1 0 1 1 1 0 Leucine rich repeat MFS_1 PF07690.11 EAU85281.2 - 1.9e-14 53.1 11.2 1.8e-10 40.1 2.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU85281.2 - 2.7e-08 32.8 0.7 5.1e-08 31.9 0.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAU85281.2 - 0.012 13.8 0.3 0.016 13.4 0.2 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EAU85281.2 - 0.13 10.6 2.4 0.22 9.8 0.1 2.0 2 0 0 2 2 2 0 MFS/sugar transport protein MFS_1 PF07690.11 EAU85282.2 - 1.2e-23 83.4 24.8 1.2e-23 83.4 17.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU85282.2 - 2.9e-09 36.0 4.2 2.9e-09 36.0 2.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter PIF1 PF05970.9 EAU85285.2 - 4.3e-24 85.1 0.0 7.6e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAU85285.2 - 2.2e-08 33.8 0.0 5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU85285.2 - 0.0004 20.0 0.0 0.00089 18.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EAU85285.2 - 0.0015 18.1 0.6 0.77 9.2 0.0 3.2 2 1 1 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.4 EAU85285.2 - 0.0041 15.8 0.0 0.0071 15.0 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EAU85285.2 - 0.045 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MAP65_ASE1 PF03999.7 EAU85286.1 - 0.82 8.1 9.0 1.2 7.6 6.2 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Cyclin_N PF00134.18 EAU85289.2 - 1.4e-12 47.3 0.0 1.9e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EAU85289.2 - 2.2e-05 24.9 0.0 3.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin Fez1 PF06818.10 EAU85290.2 - 0.017 15.1 13.7 0.023 14.7 9.5 1.1 1 0 0 1 1 1 0 Fez1 DUF2514 PF10721.4 EAU85290.2 - 1.7 8.3 11.7 2.3 7.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) APG6 PF04111.7 EAU85290.2 - 1.8 7.5 11.5 2.4 7.1 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EAU85290.2 - 2.6 6.9 7.7 4.4 6.1 5.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EAU85290.2 - 2.6 7.5 15.3 3.5 7.1 10.6 1.1 1 0 0 1 1 1 0 IncA protein Metal_resist PF13801.1 EAU85290.2 - 3.4 7.6 11.5 0.11 12.4 2.1 2.2 1 1 1 2 2 2 0 Heavy-metal resistance DUF2058 PF09831.4 EAU85290.2 - 6.3 6.6 12.0 9.3 6.0 8.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) ALMT PF11744.3 EAU85293.2 - 0.064 11.9 0.7 3.4 6.2 0.2 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter F-box-like PF12937.2 EAU85298.1 - 2.2e-09 36.8 0.9 5.2e-09 35.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU85298.1 - 0.0011 18.5 0.0 0.0042 16.6 0.0 2.0 1 0 0 1 1 1 1 F-box domain E1-E2_ATPase PF00122.15 EAU85299.1 - 1.9e-54 184.1 0.4 4.8e-54 182.8 0.3 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAU85299.1 - 7.7e-44 149.3 5.7 7.7e-44 149.3 3.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAU85299.1 - 1.4e-24 87.7 0.0 7.6e-24 85.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAU85299.1 - 3.5e-18 65.3 0.0 7.5e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAU85299.1 - 9.4e-15 55.2 0.0 4.9e-14 52.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAU85299.1 - 1.2e-07 31.0 0.1 5.5e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EAU85299.1 - 0.00039 20.0 0.2 0.0051 16.4 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_transf_20 PF00982.16 EAU85301.2 - 3e-188 626.1 0.0 1.5e-141 472.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EAU85301.2 - 0.035 13.5 0.1 9.3 5.6 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 Ribosomal_L10 PF00466.15 EAU85302.2 - 7.9e-27 93.1 0.3 1.7e-26 92.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EAU85302.2 - 1.7e-16 60.3 19.9 1.6e-15 57.2 10.9 3.3 2 1 0 2 2 2 1 60s Acidic ribosomal protein DUF1021 PF06257.6 EAU85302.2 - 0.066 12.9 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) AA_permease_2 PF13520.1 EAU85304.1 - 7.1e-72 242.2 42.6 9.2e-72 241.8 29.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAU85304.1 - 1.6e-19 69.6 37.3 2.5e-19 69.0 25.9 1.3 1 0 0 1 1 1 1 Amino acid permease Rsm1 PF08600.5 EAU85305.1 - 1.9e-13 50.0 0.1 1.5e-10 40.7 0.0 3.0 3 0 0 3 3 3 2 Rsm1-like zf-C3HC PF07967.8 EAU85305.1 - 3.9e-13 49.3 0.7 1.5e-05 24.7 0.0 3.9 3 2 1 4 4 4 3 C3HC zinc finger-like DM PF00751.13 EAU85305.1 - 0.067 12.7 1.2 3.1 7.3 0.2 2.4 2 0 0 2 2 2 0 DM DNA binding domain DEAD PF00270.24 EAU85306.2 - 7.3e-37 126.4 0.0 7.4e-36 123.1 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU85306.2 - 2.6e-21 75.2 0.1 5.7e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU85306.2 - 3.1e-10 40.1 0.0 2.4e-09 37.3 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EAU85306.2 - 0.017 14.8 0.1 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain DEAD PF00270.24 EAU85307.1 - 5.3e-34 117.1 0.4 3.1e-33 114.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU85307.1 - 1.8e-25 88.5 0.2 4.3e-25 87.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAU85307.1 - 0.0074 16.4 0.9 0.22 11.6 0.2 2.7 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 EAU85307.1 - 0.044 13.7 0.0 0.096 12.6 0.0 1.7 2 0 0 2 2 2 0 Helicase C-terminal domain WD40 PF00400.27 EAU85308.2 - 4e-28 96.2 3.0 1.5e-05 24.7 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EAU85308.2 - 0.013 15.2 0.0 0.44 10.2 0.0 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A F-box-like PF12937.2 EAU85309.2 - 3e-09 36.4 0.1 7e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85309.2 - 6.6e-08 32.0 0.0 1.8e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain CTDII PF01556.13 EAU85313.2 - 4.4e-22 77.7 0.0 5.9e-21 74.1 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EAU85313.2 - 9.3e-16 57.6 17.1 1.5e-15 56.9 11.8 1.3 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 EAU85313.2 - 1.5e-15 56.6 1.0 2.7e-15 55.8 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain HypA PF01155.14 EAU85313.2 - 0.00011 21.9 4.5 0.046 13.4 0.1 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zinc_ribbon_6 PF14599.1 EAU85313.2 - 0.011 15.5 1.0 0.011 15.5 0.7 2.4 2 0 0 2 2 2 0 Zinc-ribbon Stc1 PF12898.2 EAU85313.2 - 0.013 15.4 1.7 0.013 15.4 1.2 2.3 1 1 1 2 2 2 0 Stc1 domain PAAR_motif PF05488.8 EAU85313.2 - 0.3 11.1 6.3 0.62 10.0 0.4 2.4 1 1 1 2 2 2 0 PAAR motif DZR PF12773.2 EAU85313.2 - 0.57 10.0 6.8 3.9 7.3 0.9 2.3 2 0 0 2 2 2 0 Double zinc ribbon Stathmin PF00836.14 EAU85314.1 - 0.031 13.9 0.6 0.06 12.9 0.4 1.4 1 0 0 1 1 1 0 Stathmin family Asp PF00026.18 EAU85315.2 - 3.4e-44 151.3 0.0 4.9e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAU85315.2 - 6.1e-09 36.0 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal RasGAP PF00616.14 EAU85316.1 - 3.5e-54 183.4 0.1 1.4e-53 181.5 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EAU85316.1 - 2e-38 131.3 0.5 7.5e-38 129.4 0.3 2.1 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 EAU85316.1 - 0.0058 16.9 1.4 2.4 8.5 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF972) KxDL PF10241.4 EAU85316.1 - 0.0078 16.0 0.3 0.37 10.7 0.2 3.2 2 0 0 2 2 2 1 Uncharacterized conserved protein BRO1 PF03097.13 EAU85318.2 - 8.2e-88 294.6 0.1 1.6e-87 293.7 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EAU85318.2 - 5.8e-76 255.2 12.6 1.1e-75 254.3 8.7 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF3421 PF11901.3 EAU85319.1 - 3e-20 72.1 0.1 1.1e-17 63.8 0.0 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) SR-25 PF10500.4 EAU85319.1 - 0.00013 21.5 26.6 0.00018 21.0 18.4 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Sds3 PF08598.6 EAU85319.1 - 0.0087 15.6 5.0 0.0099 15.4 3.5 1.1 1 0 0 1 1 1 1 Sds3-like MIP-T3 PF10243.4 EAU85319.1 - 0.15 10.4 17.5 0.18 10.2 12.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 THRAP3_BCLAF1 PF15440.1 EAU85319.1 - 0.24 9.9 24.2 0.28 9.7 16.8 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF1510 PF07423.6 EAU85319.1 - 0.26 10.6 14.9 0.34 10.2 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF605 PF04652.11 EAU85319.1 - 0.26 10.6 22.6 0.34 10.2 15.6 1.1 1 0 0 1 1 1 0 Vta1 like Tim54 PF11711.3 EAU85319.1 - 2.3 6.7 9.4 3 6.3 6.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.1 EAU85319.1 - 4.4 6.9 8.1 6.7 6.3 5.6 1.3 1 0 0 1 1 1 0 FAM176 family Vfa1 PF08432.5 EAU85319.1 - 5.1 7.0 20.4 7.3 6.5 14.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WLM PF08325.5 EAU85321.2 - 9e-52 175.6 7.2 1.6e-50 171.5 1.4 3.0 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 EAU85321.2 - 4.3e-06 26.6 0.4 4.3e-06 26.6 0.3 1.9 2 1 1 3 3 3 1 Protein of unknown function DUF45 SprT-like PF10263.4 EAU85321.2 - 3.6e-05 23.4 0.0 7.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 SprT-like family zf-RanBP PF00641.13 EAU85321.2 - 4e-05 22.6 0.7 7.1e-05 21.8 0.5 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Peptidase_MA_2 PF13485.1 EAU85321.2 - 0.092 12.7 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily RhoGAP PF00620.22 EAU85323.2 - 4.7e-38 130.1 0.0 7.4e-38 129.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EAU85323.2 - 0.011 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) GMC_oxred_N PF00732.14 EAU85325.2 - 1.7e-63 214.5 0.0 1.1e-32 113.3 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU85325.2 - 3.7e-36 124.5 0.0 7.1e-36 123.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAU85325.2 - 9e-07 28.1 0.1 1.2e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAU85325.2 - 2.2e-05 23.5 0.8 0.0034 16.2 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EAU85325.2 - 5.4e-05 22.2 0.1 8.2e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAU85325.2 - 6.6e-05 22.8 0.2 0.00038 20.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EAU85325.2 - 0.00041 19.5 0.1 0.00088 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EAU85325.2 - 0.0076 14.7 0.0 0.015 13.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EAU85325.2 - 0.023 14.5 0.3 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU85325.2 - 0.077 13.4 0.3 0.54 10.7 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAU85325.2 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Exo_endo_phos PF03372.18 EAU85326.2 - 7.9e-14 52.1 0.1 4.4e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Vfa1 PF08432.5 EAU85326.2 - 8.5 6.3 13.4 16 5.4 9.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GCM PF03615.10 EAU85328.2 - 0.00082 18.9 0.7 0.0016 18.0 0.5 1.5 1 0 0 1 1 1 1 GCM motif protein GMC_oxred_N PF00732.14 EAU85330.2 - 3.6e-49 167.5 0.0 2e-32 112.5 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU85330.2 - 1.7e-40 138.6 0.0 2.6e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAU85330.2 - 1.6e-05 24.0 0.8 3e-05 23.0 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU85330.2 - 1.6e-05 23.9 0.6 2.6e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAU85330.2 - 0.00017 21.5 0.0 0.0006 19.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU85330.2 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU85330.2 - 0.0016 17.3 1.7 0.0016 17.3 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EAU85330.2 - 0.004 16.2 0.1 0.0079 15.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EAU85330.2 - 0.0093 14.4 0.3 0.013 13.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EAU85330.2 - 0.072 11.7 0.1 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GDI PF00996.13 EAU85330.2 - 0.13 10.5 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_binding_3 PF01494.14 EAU85330.2 - 0.14 11.1 0.2 0.24 10.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Drf_GBD PF06371.8 EAU85331.2 - 3.9e-14 52.4 0.0 2.7e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Glyco_hydro_17 PF00332.13 EAU85332.2 - 1.1e-13 50.9 1.1 4.8e-12 45.5 0.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF2562 PF10814.3 EAU85332.2 - 0.03 14.2 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) RNB PF00773.14 EAU85333.1 - 5.8e-47 160.5 0.0 1.4e-46 159.3 0.0 1.6 2 0 0 2 2 2 1 RNB domain DUF479 PF04336.7 EAU85333.1 - 0.066 13.3 0.2 11 6.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Spt5_N PF11942.3 EAU85333.1 - 0.1 13.2 1.7 0.68 10.5 0.1 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ABC2_membrane PF01061.19 EAU85334.2 - 3.1e-84 281.3 51.6 1.5e-44 151.7 15.5 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EAU85334.2 - 6.9e-38 130.0 0.0 1.6e-17 64.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EAU85334.2 - 9.4e-36 121.5 7.5 7.4e-29 99.4 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EAU85334.2 - 1.5e-19 69.8 0.1 4.7e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EAU85334.2 - 1e-08 34.7 0.0 0.00029 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EAU85334.2 - 5.4e-07 28.9 18.5 5.4e-07 28.9 12.8 3.8 2 2 0 3 3 2 2 ABC-2 family transporter protein DUF258 PF03193.11 EAU85334.2 - 7.4e-07 28.4 0.0 2.7e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAU85334.2 - 9.6e-07 28.9 0.1 0.001 19.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAU85334.2 - 1.1e-05 25.5 0.0 0.012 15.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EAU85334.2 - 0.00011 21.6 0.0 0.009 15.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EAU85334.2 - 0.0002 21.3 0.1 0.54 10.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAU85334.2 - 0.00085 18.8 0.8 0.052 13.0 0.1 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EAU85334.2 - 0.0011 18.6 0.9 0.27 11.0 0.3 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EAU85334.2 - 0.0011 18.7 0.1 1.8 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 EAU85334.2 - 0.0018 17.8 0.6 0.18 11.4 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EAU85334.2 - 0.002 17.6 0.0 0.27 10.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EAU85334.2 - 0.002 18.4 0.0 0.28 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU85334.2 - 0.002 18.9 0.0 0.9 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EAU85334.2 - 0.0021 17.7 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EAU85334.2 - 0.0032 16.9 0.1 2.9 7.2 0.1 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_21 PF13304.1 EAU85334.2 - 0.0064 16.5 0.0 0.71 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EAU85334.2 - 0.01 15.1 0.0 2.5 7.2 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EAU85334.2 - 0.013 15.4 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EAU85334.2 - 0.042 14.3 0.0 6.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein DUF3600 PF12207.3 EAU85334.2 - 0.092 12.2 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) Zeta_toxin PF06414.7 EAU85334.2 - 0.12 11.4 0.0 1.7 7.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EAU85334.2 - 0.14 12.3 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Septin PF00735.13 EAU85334.2 - 0.17 10.8 0.0 6.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_30 PF13604.1 EAU85334.2 - 0.19 11.3 0.2 3.2 7.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EAU85334.2 - 0.33 11.2 0.1 0.63 10.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 EAU85335.1 - 4.1e-82 276.1 0.0 5.2e-82 275.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EAU85336.1 - 1.7e-09 37.2 0.3 3.9e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85336.1 - 7.8e-05 22.2 0.5 7.8e-05 22.2 0.4 1.9 2 0 0 2 2 2 1 F-box domain DUF4638 PF15472.1 EAU85336.1 - 0.25 10.8 0.2 0.41 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Gp-FAR-1 PF05823.7 EAU85337.2 - 0.15 11.9 0.6 0.34 10.8 0.4 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF605 PF04652.11 EAU85339.2 - 0.11 11.8 4.4 0.13 11.6 3.1 1.1 1 0 0 1 1 1 0 Vta1 like Sec3_C PF09763.4 EAU85339.2 - 0.12 10.4 0.2 0.14 10.2 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF4602 PF15375.1 EAU85339.2 - 0.39 10.7 0.0 0.39 10.7 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4602) MFS_1 PF07690.11 EAU85340.2 - 1.5e-30 106.1 27.7 1.9e-29 102.5 19.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU85340.2 - 2.5e-08 32.9 16.7 5.9e-06 25.1 2.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EAU85340.2 - 4.4e-06 25.3 14.7 0.00062 18.2 3.8 2.8 2 1 2 4 4 4 2 MFS/sugar transport protein NicO PF03824.11 EAU85340.2 - 0.029 13.6 5.3 0.24 10.6 0.4 2.3 2 0 0 2 2 2 0 High-affinity nickel-transport protein Pkinase PF00069.20 EAU85342.2 - 0.00017 20.8 0.0 0.00032 19.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85342.2 - 0.015 14.3 0.1 0.023 13.7 0.1 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Choline_kin_N PF04428.9 EAU85342.2 - 0.025 14.0 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus CwfJ_C_2 PF04676.9 EAU85342.2 - 0.047 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 ATP-synt_J PF04911.7 EAU85342.2 - 0.065 12.6 0.3 7.8 6.0 0.0 2.6 2 1 0 2 2 2 0 ATP synthase j chain SPT2 PF08243.6 EAU85344.1 - 3.8e-12 46.5 15.9 3.8e-12 46.5 11.0 4.0 3 1 1 4 4 4 1 SPT2 chromatin protein OmpH PF03938.9 EAU85344.1 - 3.1 7.7 24.1 3.9 7.3 11.5 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SHQ1 PF04925.10 EAU85345.2 - 0.043 13.2 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 SHQ1 protein Vps51 PF08700.6 EAU85348.1 - 3e-24 84.6 0.8 4.3e-24 84.1 0.6 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EAU85348.1 - 0.00027 20.8 3.1 0.00038 20.4 2.1 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EAU85348.1 - 0.002 16.6 1.5 0.0025 16.3 1.1 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.7 EAU85348.1 - 0.011 15.9 1.8 0.018 15.3 1.2 1.3 1 0 0 1 1 1 0 FlgN protein AAA PF00004.24 EAU85352.1 - 1.7e-42 144.7 0.0 3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU85352.1 - 2.4e-06 27.7 0.1 0.00041 20.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EAU85352.1 - 3e-06 27.2 0.0 6.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAU85352.1 - 1.4e-05 24.7 0.1 6.7e-05 22.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EAU85352.1 - 5.6e-05 22.1 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EAU85352.1 - 7.9e-05 22.7 0.1 0.0015 18.5 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EAU85352.1 - 0.00088 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAU85352.1 - 0.00091 18.3 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EAU85352.1 - 0.0039 16.8 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU85352.1 - 0.006 17.3 0.7 0.016 16.0 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EAU85352.1 - 0.0072 16.0 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EAU85352.1 - 0.0079 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EAU85352.1 - 0.011 14.8 0.2 0.32 10.0 0.1 2.2 1 1 1 2 2 2 0 KaiC IstB_IS21 PF01695.12 EAU85352.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EAU85352.1 - 0.014 15.3 0.4 0.076 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAU85352.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EAU85352.1 - 0.02 14.2 0.8 2.1 7.6 0.2 2.5 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EAU85352.1 - 0.025 14.0 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EAU85352.1 - 0.034 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 EAU85352.1 - 0.034 12.8 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EAU85352.1 - 0.039 14.2 1.4 0.043 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain SKI PF01202.17 EAU85352.1 - 0.043 13.6 0.0 3.8 7.3 0.0 2.7 2 1 0 2 2 2 0 Shikimate kinase NACHT PF05729.7 EAU85352.1 - 0.068 12.8 0.1 0.45 10.1 0.1 2.3 3 0 0 3 3 3 0 NACHT domain DUF2075 PF09848.4 EAU85352.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EAU85352.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EAU85352.1 - 0.14 11.7 0.1 0.36 10.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAU85352.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Med26 PF08711.6 EAU85354.1 - 5.2e-11 41.8 0.0 1.5e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TPR_11 PF13414.1 EAU85357.2 - 8.3e-12 44.5 3.2 4.2e-09 35.9 2.1 2.8 1 1 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EAU85357.2 - 1.5e-09 37.0 7.1 0.00085 19.0 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAU85357.2 - 5e-07 29.0 3.0 0.0057 16.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU85357.2 - 5.3e-06 26.6 0.1 0.4 11.4 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU85357.2 - 4e-05 23.4 0.7 0.033 14.1 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU85357.2 - 8.7e-05 22.0 0.1 4.8 7.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU85357.2 - 0.00011 22.2 0.3 0.0044 17.1 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EAU85357.2 - 0.00049 20.6 1.2 7.1 7.4 0.0 3.4 3 1 0 3 3 2 1 Tetratricopeptide repeat PPR PF01535.15 EAU85357.2 - 0.001 18.8 0.3 0.33 11.0 0.0 3.3 3 0 0 3 3 3 1 PPR repeat TPR_6 PF13174.1 EAU85357.2 - 0.0017 18.6 0.8 5.5 7.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAU85357.2 - 0.0021 18.1 0.6 0.34 11.2 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat Spore_III_AB PF09548.5 EAU85357.2 - 0.0027 17.4 0.3 0.0048 16.6 0.2 1.4 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) TPR_19 PF14559.1 EAU85357.2 - 0.0039 17.4 3.1 0.047 14.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU85357.2 - 0.011 15.5 7.6 5.9 6.9 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU85357.2 - 0.073 13.0 0.0 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3087 PF11286.3 EAU85357.2 - 0.1 11.8 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Phosphonate-bd PF12974.2 EAU85358.2 - 5.7e-05 22.6 0.0 7.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EAU85358.2 - 6.7e-05 22.5 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EAU85358.2 - 0.00015 21.0 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 EAU85358.2 - 0.0081 15.5 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family GSHPx PF00255.14 EAU85361.2 - 4.1e-15 55.0 0.0 2e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 Glutathione peroxidase DUF4174 PF13778.1 EAU85361.2 - 0.0022 18.0 0.0 0.0032 17.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) Ral PF11058.3 EAU85361.2 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein Ral ACBP PF00887.14 EAU85363.1 - 4.7e-30 103.1 0.1 6.5e-30 102.6 0.1 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.24 EAU85364.1 - 5.5e-33 113.2 0.1 6.3e-19 68.1 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EAU85364.1 - 1.9e-17 63.5 4.1 2.3e-08 34.2 1.2 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EAU85364.1 - 3.6e-12 46.0 0.0 1.7e-06 27.8 0.0 3.3 3 0 0 3 3 3 3 PH domain PH_8 PF15409.1 EAU85364.1 - 2e-06 27.7 0.5 0.0003 20.8 0.1 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.1 EAU85364.1 - 2.7e-05 24.2 0.9 0.0077 16.3 0.2 3.4 2 2 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EAU85364.1 - 0.00021 21.1 0.3 1.1 9.1 0.2 2.7 2 1 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 EAU85364.1 - 0.0073 15.8 0.1 0.099 12.1 0.0 2.6 2 1 1 3 3 3 1 Pleckstrin homology domain Fungal_trans_2 PF11951.3 EAU85365.2 - 2e-25 89.2 0.0 2.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU85365.2 - 0.00011 22.0 9.1 0.00023 21.0 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2388 PF09498.5 EAU85365.2 - 0.09 12.4 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) Fungal_trans_2 PF11951.3 EAU85366.2 - 6.2e-47 160.0 1.5 8.2e-47 159.6 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU85366.2 - 0.00027 20.7 10.3 0.0005 19.9 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VTC PF09359.5 EAU85368.2 - 1.4e-95 319.5 0.4 2.3e-95 318.8 0.0 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EAU85368.2 - 1.8e-22 80.4 10.7 6.4e-14 52.3 0.6 3.3 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EAU85368.2 - 1.3e-07 31.6 3.8 2.7e-07 30.6 2.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Clc-like PF07062.7 EAU85368.2 - 0.18 11.0 0.8 0.34 10.1 0.6 1.4 1 0 0 1 1 1 0 Clc-like Gtr1_RagA PF04670.7 EAU85369.2 - 1.9e-49 167.8 0.1 2.6e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EAU85369.2 - 0.00031 20.0 0.1 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Arch_ATPase PF01637.13 EAU85369.2 - 0.00035 20.3 0.1 0.0048 16.6 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase Miro PF08477.8 EAU85369.2 - 0.00056 20.3 0.1 0.0024 18.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EAU85369.2 - 0.00073 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EAU85369.2 - 0.0035 17.2 0.1 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 EAU85369.2 - 0.029 13.5 0.1 0.059 12.5 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 EAU85369.2 - 0.056 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras family Acyl_transf_1 PF00698.16 EAU85370.1 - 8.9e-68 228.9 0.0 6.7e-65 219.5 0.0 3.4 3 0 0 3 3 3 1 Acyl transferase domain DUF1729 PF08354.5 EAU85370.1 - 2.1e-28 97.8 2.1 8.6e-28 95.9 1.5 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EAU85370.1 - 2.9e-27 94.4 0.0 8.4e-27 92.9 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.21 EAU85370.1 - 3e-25 89.1 0.7 6.6e-25 88.0 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EAU85370.1 - 2.1e-19 70.2 0.0 6.5e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 EAU85370.1 - 6.1e-16 58.4 0.0 1.5e-14 53.8 0.0 3.0 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase ACPS PF01648.15 EAU85370.1 - 2.5e-15 56.2 0.0 6.3e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EAU85370.1 - 2e-14 53.4 0.0 4.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain IucA_IucC PF04183.7 EAU85373.2 - 2.1e-28 99.2 0.3 7.9e-28 97.3 0.2 1.9 1 1 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 EAU85373.2 - 3.2e-14 53.2 0.1 6.2e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.7 EAU85374.2 - 1.2e-15 57.4 0.1 9.7e-12 44.6 0.0 2.3 2 0 0 2 2 2 2 IucA / IucC family FhuF PF06276.7 EAU85374.2 - 3.4e-14 53.1 0.3 5.4e-14 52.4 0.2 1.3 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter C2 PF00168.25 EAU85375.2 - 1.4e-14 53.6 0.2 6.6e-14 51.5 0.1 2.0 2 0 0 2 2 2 1 C2 domain Frag1 PF10277.4 EAU85376.2 - 1.8e-35 122.3 19.0 5.1e-23 81.6 6.4 2.0 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 EAU85376.2 - 0.0016 17.8 11.3 0.0016 17.8 7.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF998) Bax1-I PF01027.15 EAU85376.2 - 0.011 15.3 17.9 0.021 14.4 12.4 1.5 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Voltage_CLC PF00654.15 EAU85376.2 - 0.012 14.6 4.3 0.018 14.1 3.0 1.3 1 0 0 1 1 1 0 Voltage gated chloride channel Peptidase_U4 PF03419.8 EAU85376.2 - 0.75 8.8 6.8 0.21 10.6 2.6 1.6 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DSBA PF01323.15 EAU85377.1 - 1.2e-26 93.4 0.0 1.5e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EAU85377.1 - 0.024 14.6 0.7 0.037 14.0 0.0 1.7 2 1 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 EAU85377.1 - 0.026 14.3 0.1 0.22 11.3 0.0 2.7 2 2 0 2 2 2 0 Thioredoxin domain F-box-like PF12937.2 EAU85378.2 - 5.7e-09 35.5 1.0 3.3e-08 33.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAU85378.2 - 0.00075 19.0 3.8 0.53 9.9 0.1 5.3 3 2 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 EAU85378.2 - 0.0019 18.5 0.6 0.37 11.3 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 EAU85378.2 - 0.078 13.2 4.4 1.3e+02 3.4 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 EAU85378.2 - 0.35 11.0 7.8 56 4.2 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich repeat NADHdh_A3 PF14987.1 EAU85379.2 - 0.14 12.1 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Cation_ATPase_C PF00689.16 EAU85379.2 - 0.14 11.6 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus SART-1 PF03343.8 EAU85380.2 - 4.5e-120 401.8 68.8 4.5e-120 401.8 47.7 1.7 2 0 0 2 2 2 1 SART-1 family RNase_HII PF01351.13 EAU85381.1 - 4.5e-48 163.5 0.0 6.3e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII TFIIS_C PF01096.13 EAU85382.2 - 1.6e-14 53.2 1.8 1.6e-14 53.2 1.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EAU85382.2 - 1.4e-09 37.4 4.0 1.4e-09 37.4 2.8 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.1 EAU85382.2 - 0.00097 19.3 2.3 0.38 11.0 0.3 2.2 2 0 0 2 2 2 2 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.1 EAU85382.2 - 0.002 18.3 0.8 0.002 18.3 0.5 2.4 2 1 0 2 2 2 1 Restriction alleviation protein Lar DUF2387 PF09526.5 EAU85382.2 - 0.014 15.2 0.4 0.014 15.2 0.3 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 EAU85382.2 - 0.019 14.6 2.8 0.36 10.5 0.0 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1 PF03811.8 EAU85382.2 - 0.048 13.1 1.2 0.048 13.1 0.9 2.5 2 2 0 2 2 2 0 InsA N-terminal domain GFA PF04828.9 EAU85382.2 - 0.068 13.1 4.7 4.3 7.3 1.3 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ISL3 PF14690.1 EAU85382.2 - 0.12 12.4 0.1 0.12 12.4 0.0 2.8 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 UPF0547 PF10571.4 EAU85382.2 - 0.25 11.0 12.6 0.35 10.6 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-C2H2_4 PF13894.1 EAU85382.2 - 0.28 11.6 5.5 21 5.7 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.7 EAU85382.2 - 0.53 10.3 12.5 2.8 7.9 1.9 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain Prim_Zn_Ribbon PF08273.7 EAU85382.2 - 0.93 9.6 8.7 0.14 12.2 1.2 2.8 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase DZR PF12773.2 EAU85382.2 - 1.4 8.7 11.0 5.6 6.8 1.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-IS66 PF13005.2 EAU85382.2 - 2.2 8.3 6.4 40 4.2 0.0 3.7 3 1 1 4 4 4 0 zinc-finger binding domain of transposase IS66 Zn_Tnp_IS1595 PF12760.2 EAU85382.2 - 2.2 8.1 12.4 0.22 11.3 1.7 3.1 2 2 0 2 2 2 0 Transposase zinc-ribbon domain C1_1 PF00130.17 EAU85382.2 - 4.1 7.1 8.9 0.1 12.3 0.4 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EAU85382.2 - 4.2 7.3 13.5 6 6.8 0.3 3.8 4 0 0 4 4 4 0 Zinc ribbon domain zf-Mss51 PF13824.1 EAU85382.2 - 5.5 6.9 8.0 2.5 7.9 2.6 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.8 EAU85382.2 - 5.7 6.5 11.4 13 5.3 0.0 4.0 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EAU85382.2 - 5.9 6.6 7.1 2.6 7.7 1.9 2.5 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EAU85382.2 - 6.5 6.3 10.7 2.2 7.8 0.4 3.2 3 1 0 3 3 3 0 zinc-ribbon domain RRN7 PF11781.3 EAU85382.2 - 8.1 6.0 13.6 12 5.4 1.7 3.5 4 0 0 4 4 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 CpXC PF14353.1 EAU85382.2 - 8.8 6.3 10.0 10 6.1 0.3 3.1 2 1 0 2 2 2 0 CpXC protein Ribosomal_S27e PF01667.12 EAU85382.2 - 9.4 5.8 9.3 1.7 8.2 1.1 3.2 2 2 0 2 2 2 0 Ribosomal protein S27 LsmAD PF06741.8 EAU85383.2 - 1.7e-26 92.0 0.1 4.8e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EAU85383.2 - 1.9e-09 37.3 0.0 3.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Mad3_BUB1_I PF08311.7 EAU85384.1 - 3.9e-30 104.2 4.5 6.8e-30 103.4 3.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EAU85384.1 - 1.1e-15 57.4 0.0 3.7e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85384.1 - 2.2e-07 30.2 0.0 3.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EAU85384.1 - 7.7e-05 22.5 0.0 0.00029 20.6 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 vWA-TerF-like PF10138.4 EAU85385.2 - 0.062 13.1 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus Adeno_PIX PF03955.9 EAU85385.2 - 0.13 12.7 6.0 3 8.3 0.0 3.6 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Acetyltransf_3 PF13302.1 EAU85386.1 - 3.1e-10 40.3 0.0 4.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU85386.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.19 EAU85390.1 - 6.8e-68 229.2 26.9 2.1e-48 165.0 2.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAU85390.1 - 7.7e-18 64.3 41.1 5.3e-16 58.2 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AflR PF08493.5 EAU85391.2 - 2 7.3 16.1 3.9 6.4 11.2 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein MCLC PF05934.6 EAU85391.2 - 3.8 5.6 5.9 4.6 5.4 4.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Exo_endo_phos PF03372.18 EAU85392.2 - 7.8e-11 42.3 0.0 1.1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thioredoxin PF00085.15 EAU85393.2 - 1.9e-39 133.5 0.1 3.2e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EAU85393.2 - 6.4e-22 78.0 3.4 9.2e-21 74.2 2.2 2.5 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EAU85393.2 - 4.7e-09 36.4 2.5 4.9e-05 23.4 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EAU85393.2 - 1.6e-05 24.7 0.1 0.0024 17.6 0.0 3.0 1 1 2 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EAU85393.2 - 2.5e-05 24.1 0.0 0.3 11.1 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EAU85393.2 - 0.0013 18.7 0.3 12 6.0 0.1 3.8 2 2 2 4 4 4 1 Thioredoxin-like Enterotoxin_b PF01376.13 EAU85393.2 - 0.041 13.7 0.2 0.082 12.7 0.2 1.5 1 0 0 1 1 1 0 Heat-labile enterotoxin beta chain DUF349 PF03993.7 EAU85393.2 - 0.72 10.0 7.6 0.49 10.5 2.1 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) WD40 PF00400.27 EAU85394.1 - 9.1e-48 158.5 24.3 4.1e-11 42.3 0.1 8.2 8 1 0 8 8 8 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EAU85394.1 - 0.00047 19.6 1.9 0.0046 16.4 0.0 2.7 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EAU85394.1 - 0.0076 14.4 0.3 0.19 9.8 0.1 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Lipase_3 PF01764.20 EAU85395.2 - 1.5e-07 31.1 0.0 3.1e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EAU85395.2 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EAU85395.2 - 0.2 11.1 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Trehalase PF01204.13 EAU85396.2 - 8.6e-165 549.2 0.0 1.1e-164 548.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EAU85396.2 - 8.2e-12 44.2 0.0 1.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF155 PF02582.9 EAU85397.2 - 9.4e-43 146.1 0.0 1.3e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RhoGEF PF00621.15 EAU85398.2 - 2e-32 112.5 0.2 3.3e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 EAU85398.2 - 2.2e-17 63.4 0.0 5e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH PF00169.24 EAU85398.2 - 0.067 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 PH domain eIF-6 PF01912.13 EAU85399.1 - 3.2e-87 290.7 0.4 3.2e-87 290.7 0.3 1.5 2 0 0 2 2 2 1 eIF-6 family Methyltransf_28 PF02636.12 EAU85400.2 - 1.1e-63 214.9 0.0 1.4e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase IL11 PF07400.6 EAU85402.2 - 0.37 10.2 2.7 0.17 11.3 0.2 1.7 2 0 0 2 2 2 0 Interleukin 11 Ctf8 PF09696.5 EAU85403.1 - 1.2e-17 63.8 0.0 1.8e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Ctf8 AhpC-TSA_2 PF13911.1 EAU85404.2 - 5.5e-16 58.5 0.0 1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EAU85404.2 - 7.3e-06 25.6 0.0 0.00031 20.4 0.0 2.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EAU85404.2 - 0.082 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Redoxin PTPlike_phytase PF14566.1 EAU85408.2 - 3.4e-124 410.1 0.0 3.9e-41 140.5 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 EAU85408.2 - 2.7e-05 23.7 0.0 0.071 12.6 0.0 3.5 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAU85408.2 - 0.0011 18.4 0.2 0.084 12.1 0.0 3.1 3 0 0 3 3 3 1 Protein-tyrosine phosphatase TFIIE-A_C-term PF11521.3 EAU85408.2 - 0.0012 18.7 0.0 1.7 8.6 0.0 3.3 3 0 0 3 3 3 2 C-terminal general transcription factor TFIIE alpha DUF3734 PF12536.3 EAU85408.2 - 0.079 13.0 0.1 0.079 13.0 0.0 2.5 3 0 0 3 3 3 0 Patatin phospholipase SIR2 PF02146.12 EAU85410.2 - 1.7e-31 109.3 0.0 4.9e-21 75.2 0.0 2.6 2 0 0 2 2 2 2 Sir2 family BmKX PF09132.5 EAU85410.2 - 0.0083 15.9 0.9 0.091 12.6 0.0 2.5 2 0 0 2 2 2 1 BmKX Trm112p PF03966.11 EAU85410.2 - 0.0085 16.4 0.1 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 Trm112p-like protein TPP_enzyme_M PF00205.17 EAU85410.2 - 0.05 13.3 0.1 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain 6PF2K PF01591.13 EAU85412.2 - 3.6e-69 232.2 0.0 4.9e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EAU85412.2 - 1.3e-32 113.0 0.0 6.3e-32 110.8 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EAU85412.2 - 6.5e-07 29.3 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU85412.2 - 0.0011 19.7 0.1 0.0044 17.8 0.0 2.1 2 1 1 3 3 3 1 AAA domain Methyltransf_32 PF13679.1 EAU85412.2 - 0.0092 15.6 0.2 0.037 13.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Zeta_toxin PF06414.7 EAU85412.2 - 0.042 12.9 0.1 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin GBP PF02263.14 EAU85412.2 - 0.17 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Pkinase PF00069.20 EAU85414.2 - 5.6e-25 87.9 0.0 7.7e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85414.2 - 3.3e-05 23.0 0.0 4.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N PF00107.21 EAU85415.1 - 5.7e-16 58.2 0.0 1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU85415.1 - 3.8e-07 31.0 0.0 7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.11 EAU85415.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ELFV_dehydrog PF00208.16 EAU85415.1 - 0.13 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IncA PF04156.9 EAU85416.2 - 0.054 13.1 2.1 2 7.9 0.2 2.3 2 0 0 2 2 2 0 IncA protein Herpes_gE PF02480.11 EAU85416.2 - 0.21 9.7 0.0 0.35 9.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4175 PF13779.1 EAU85416.2 - 0.46 8.1 6.0 0.65 7.6 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Syndecan PF01034.15 EAU85417.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Herpes_gE PF02480.11 EAU85417.1 - 0.18 10.0 0.0 0.47 8.6 0.0 1.5 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Con-6 PF10346.4 EAU85418.1 - 7.3e-31 105.2 2.6 4.2e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 EAU85418.1 - 0.69 9.3 3.9 1 8.8 0.0 2.5 1 1 1 2 2 2 0 SpoIIIAH-like protein DUF2537 PF10801.3 EAU85419.2 - 0.056 13.5 2.8 0.063 13.3 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Oleosin PF01277.12 EAU85419.2 - 0.94 9.0 3.7 0.34 10.4 0.4 1.8 1 1 0 1 1 1 0 Oleosin DRY_EERY PF09750.4 EAU85421.2 - 3.4 7.7 8.0 6.4 6.9 5.3 1.6 1 1 0 1 1 1 0 Alternative splicing regulator F-box-like PF12937.2 EAU85425.2 - 4.5e-08 32.6 0.7 1.4e-07 31.0 0.5 2.0 1 0 0 1 1 1 1 F-box-like SGL PF08450.7 EAU85427.2 - 9.1e-05 21.9 0.0 0.0004 19.8 0.0 2.0 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EAU85427.2 - 0.00061 19.7 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 Arylesterase Lactonase PF10282.4 EAU85427.2 - 0.014 14.4 0.0 0.07 12.1 0.0 1.9 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Str_synth PF03088.11 EAU85427.2 - 0.14 12.1 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase DUF2824 PF11039.3 EAU85428.2 - 0.0058 16.3 1.4 0.01 15.5 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2824) Xpo1 PF08389.7 EAU85429.2 - 2.5e-20 72.9 0.1 8.8e-19 67.8 0.0 3.5 3 1 1 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 EAU85429.2 - 0.06 13.4 0.8 2.2 8.5 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat WD40 PF00400.27 EAU85430.1 - 5.4e-28 95.8 7.0 7.7e-07 28.7 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EAU85430.1 - 0.0011 18.7 0.1 1.1 8.9 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EAU85430.1 - 0.07 12.6 0.0 0.76 9.3 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.17 EAU85431.2 - 3.1e-48 164.4 0.0 4.1e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_hydroxylase PF04116.8 EAU85433.2 - 4.3e-15 56.0 29.2 8.1e-15 55.2 17.1 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF1295 PF06966.7 EAU85434.2 - 7.4e-43 146.5 0.2 9.9e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EAU85434.2 - 1.3e-05 23.9 0.0 2.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EAU85434.2 - 2.3e-05 24.4 0.0 6.1e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 EAU85434.2 - 0.0003 20.9 0.0 0.0009 19.3 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EAU85434.2 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Glyco_hydro_7 PF00840.15 EAU85436.1 - 1.7e-207 688.9 10.8 2e-207 688.7 7.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF4506 PF14958.1 EAU85436.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) Glyco_hydro_7 PF00840.15 EAU85437.1 - 1.4e-207 689.2 11.0 1.6e-207 689.0 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.15 EAU85438.2 - 1.7e-207 689.0 12.5 2e-207 688.8 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 UPRTase PF14681.1 EAU85440.1 - 3.4e-46 157.0 0.0 4.8e-44 150.0 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase PRK PF00485.13 EAU85440.1 - 8.3e-38 129.8 0.0 1.4e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family dNK PF01712.14 EAU85440.1 - 0.12 12.2 0.0 0.42 10.5 0.0 2.0 2 1 0 2 2 2 0 Deoxynucleoside kinase Peptidase_C14 PF00656.17 EAU85441.2 - 2.6e-69 233.6 0.0 3e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Sugar_tr PF00083.19 EAU85443.2 - 7.4e-114 380.7 22.6 9.4e-114 380.4 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU85443.2 - 1.7e-28 99.3 63.7 5.9e-23 81.1 19.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAU85443.2 - 0.0022 16.4 36.2 0.0033 15.8 7.0 3.9 2 2 1 3 3 3 2 MFS/sugar transport protein PIRT PF15099.1 EAU85443.2 - 0.27 10.4 1.5 0.6 9.3 1.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Isochorismatase PF00857.15 EAU85444.2 - 2.4e-15 56.8 0.0 3.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family COX5B PF01215.14 EAU85445.1 - 9.4e-40 135.4 0.0 1.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Collagen PF01391.13 EAU85447.1 - 9.1e-06 25.1 18.4 9.1e-06 25.1 12.7 2.7 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) FAD_binding_4 PF01565.18 EAU85448.2 - 1.2e-21 76.6 0.2 2.5e-21 75.6 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU85448.2 - 1.2e-13 50.6 0.3 2.7e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like CIA30 PF08547.7 EAU85450.1 - 1.4e-24 86.7 0.0 1.7e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) IMS PF00817.15 EAU85452.2 - 1.4e-38 131.9 0.0 2.8e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EAU85452.2 - 5.7e-13 48.9 0.0 1.2e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain Pyr_redox_2 PF07992.9 EAU85453.1 - 1.3e-31 110.0 1.5 2.2e-31 109.3 1.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EAU85453.1 - 1.3e-15 56.7 0.0 3.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EAU85453.1 - 8.7e-12 45.5 0.1 4.2e-06 26.9 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU85453.1 - 1.4e-10 41.3 0.2 1.4e-10 41.3 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EAU85453.1 - 1.1e-07 32.0 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 EAU85453.1 - 4.3e-07 29.6 0.0 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 EAU85453.1 - 0.00014 20.9 0.0 0.21 10.4 0.0 2.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EAU85453.1 - 0.002 17.2 0.0 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Glyco_tran_WecB PF03808.8 EAU85453.1 - 0.024 14.0 0.1 0.3 10.4 0.0 2.7 3 1 0 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family PQQ_3 PF13570.1 EAU85453.1 - 0.84 9.9 3.5 8.3 6.8 0.8 3.4 2 1 0 2 2 2 0 PQQ-like domain DUF1295 PF06966.7 EAU85454.1 - 3.1e-33 115.0 10.4 1.2e-31 109.8 5.8 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1295) Metallophos PF00149.23 EAU85455.2 - 2.4e-09 36.8 0.4 5.5e-09 35.7 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU85455.2 - 7.4e-09 35.6 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_7 PF00840.15 EAU85456.2 - 7.5e-204 677.0 12.4 8.6e-204 676.8 8.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fungal_trans PF04082.13 EAU85461.2 - 3.5e-18 65.4 0.2 5.2e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE_assoc PF09335.6 EAU85462.2 - 3.5e-12 46.6 4.5 3.5e-12 46.6 3.1 2.3 4 0 0 4 4 4 1 SNARE associated Golgi protein Colicin PF01024.14 EAU85462.2 - 0.06 12.9 0.4 0.06 12.9 0.3 1.6 2 0 0 2 2 2 0 Colicin pore forming domain ARID PF01388.16 EAU85463.2 - 1.2e-10 41.1 0.0 2.9e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.7 EAU85463.2 - 0.00025 21.0 1.3 0.0043 16.9 0.1 2.6 2 1 0 2 2 2 1 Mediator complex subunit 15 SRP-alpha_N PF04086.8 EAU85463.2 - 0.061 12.7 0.1 0.061 12.7 0.1 3.1 2 1 0 3 3 3 0 Signal recognition particle, alpha subunit, N-terminal EcoRI PF02963.11 EAU85463.2 - 0.42 9.3 0.0 0.87 8.3 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease EcoRI Tweety PF04906.8 EAU85463.2 - 0.79 8.0 0.4 1.6 7.0 0.3 1.4 1 0 0 1 1 1 0 Tweety DUF572 PF04502.8 EAU85464.2 - 1.5e-40 139.4 1.7 2.1e-40 138.9 1.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Chitin_bind_4 PF00379.18 EAU85464.2 - 0.76 10.0 3.7 7.6 6.8 0.1 2.9 3 0 0 3 3 3 0 Insect cuticle protein CTDII PF01556.13 EAU85466.2 - 0.041 13.7 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 DnaJ C terminal domain zf-C3HC4_3 PF13920.1 EAU85468.2 - 1.6 8.4 8.6 0.92 9.2 4.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 EAU85469.1 - 9.7e-45 152.7 0.0 7.9e-25 87.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85469.1 - 9.3e-21 74.0 0.0 2.3e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAU85469.1 - 1.5e-07 30.6 0.0 0.00011 21.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EAU85469.1 - 0.00032 20.5 0.2 0.0017 18.1 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family MIF4G PF02854.14 EAU85470.2 - 7.5e-27 94.1 2.0 7.5e-27 94.1 1.4 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EAU85470.2 - 2.3e-21 75.6 0.1 1.5e-20 72.9 0.0 2.5 2 1 0 2 2 2 1 MA3 domain Pox_P35 PF03213.9 EAU85470.2 - 0.13 11.2 1.6 0.39 9.6 0.2 2.1 2 0 0 2 2 2 0 Poxvirus P35 protein Pkinase PF00069.20 EAU85472.2 - 6.1e-60 202.5 0.0 9.1e-60 201.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85472.2 - 1.2e-32 113.0 0.0 1.7e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU85472.2 - 8.8e-08 31.4 0.0 1.9e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAU85472.2 - 0.0047 16.6 0.4 0.0092 15.7 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EAU85472.2 - 0.0082 15.2 0.1 0.021 13.9 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EAU85472.2 - 0.15 10.8 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Macro PF01661.16 EAU85473.2 - 9.1e-40 135.2 0.2 1.3e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 Macro domain PTS_2-RNA PF01885.11 EAU85474.2 - 2.9e-12 46.3 0.0 2.7e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 RNA 2'-phosphotransferase, Tpt1 / KptA family Pex14_N PF04695.8 EAU85474.2 - 2.5 8.1 10.6 2.4 8.2 1.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_19 PF14559.1 EAU85476.1 - 3.2e-15 56.2 5.6 2.3e-06 27.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU85476.1 - 2e-14 53.7 0.4 1.2e-05 25.7 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAU85476.1 - 7.2e-11 41.5 0.1 0.0031 17.1 0.0 3.9 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.1 EAU85476.1 - 5.2e-10 39.0 7.5 0.21 12.3 0.1 6.4 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAU85476.1 - 3.1e-09 36.0 2.9 0.29 11.1 0.0 5.8 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EAU85476.1 - 1.3e-08 34.8 0.1 6.2e-05 23.0 0.0 3.5 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EAU85476.1 - 1.8e-08 34.1 0.7 0.0037 17.1 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAU85476.1 - 1.1e-07 31.4 0.1 0.0052 16.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU85476.1 - 6.8e-07 28.6 1.0 1.2 8.8 0.2 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAU85476.1 - 0.0012 19.1 4.2 1.3 9.6 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EAU85476.1 - 0.013 15.7 0.4 0.21 11.8 0.1 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation SRF-TF PF00319.13 EAU85476.1 - 0.033 13.4 0.2 0.06 12.5 0.2 1.4 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) TPR_20 PF14561.1 EAU85476.1 - 0.042 13.9 3.0 2.8 8.1 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAU85476.1 - 0.046 13.5 0.1 50 4.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAU85476.1 - 0.05 13.4 0.1 20 5.2 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAU85476.1 - 0.062 13.1 0.3 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EAU85476.1 - 0.064 13.2 0.1 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EAU85476.1 - 0.069 13.6 0.1 3.1 8.5 0.0 3.4 4 0 0 4 4 2 0 Tetratricopeptide repeat Glyco_hydro_43 PF04616.9 EAU85477.2 - 2.4e-66 223.7 1.5 3e-66 223.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Svf1 PF08622.5 EAU85479.2 - 4.6e-85 285.4 0.0 5.2e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Svf1-like Glyco_transf_90 PF05686.7 EAU85480.2 - 6.9e-20 71.0 0.1 1.7e-19 69.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 Peptidase_M48 PF01435.13 EAU85481.2 - 5.1e-10 39.2 0.0 1e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 EAU85481.2 - 0.19 11.0 0.2 0.32 10.3 0.2 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) F_bP_aldolase PF01116.15 EAU85482.2 - 1.1e-46 159.2 0.0 4.2e-33 114.6 0.0 2.1 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-II Dimeth_Pyl PF09505.5 EAU85482.2 - 0.089 11.0 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Na_Ca_ex PF01699.19 EAU85483.2 - 9.5e-32 109.5 31.0 7e-20 71.0 9.7 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein LRR_6 PF13516.1 EAU85484.2 - 0.00017 21.3 1.5 0.028 14.4 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 EAU85484.2 - 0.0074 16.3 4.4 4.3 7.9 0.0 5.9 6 0 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 EAU85484.2 - 0.011 15.5 1.9 2.2 8.6 0.0 4.5 4 2 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.2 EAU85484.2 - 0.02 14.5 0.8 0.043 13.5 0.6 1.5 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EAU85484.2 - 0.023 14.3 8.5 0.42 10.2 0.0 4.6 4 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Lactococcin PF04369.8 EAU85484.2 - 0.19 11.7 0.9 2.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Lactococcin-like family LRR_8 PF13855.1 EAU85484.2 - 6.3 6.6 5.6 28 4.5 0.0 3.8 4 2 0 4 4 4 0 Leucine rich repeat Erg28 PF03694.8 EAU85485.1 - 1.5e-40 137.6 4.0 1.8e-40 137.4 2.8 1.1 1 0 0 1 1 1 1 Erg28 like protein GIIM PF08388.6 EAU85485.1 - 0.002 17.8 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Group II intron, maturase-specific domain TPK_catalytic PF04263.11 EAU85487.2 - 1.7e-21 76.0 0.0 3.9e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EAU85487.2 - 5.9e-18 64.3 0.1 1.1e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CS PF04969.11 EAU85487.2 - 1.2e-09 38.6 0.0 4e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 CS domain Sel1 PF08238.7 EAU85487.2 - 0.037 14.6 2.8 2.4 8.8 0.1 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_2 PF07719.12 EAU85487.2 - 0.72 9.9 4.0 1.8 8.6 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4078 PF13300.1 EAU85488.1 - 1.5e-20 73.0 3.5 1.5e-20 73.0 2.4 3.7 3 1 1 4 4 4 2 Domain of unknown function (DUF4078) DUF903 PF06004.7 EAU85488.1 - 0.033 13.7 0.1 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) LRR_4 PF12799.2 EAU85489.2 - 8.7e-57 187.9 61.5 1.2e-10 40.7 1.7 7.6 3 2 7 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU85489.2 - 5e-37 125.4 64.7 4.5e-10 39.1 4.6 5.4 1 1 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EAU85489.2 - 4.1e-18 62.6 33.2 0.16 12.1 0.1 11.5 12 0 0 12 12 12 8 Leucine Rich Repeat LRR_9 PF14580.1 EAU85489.2 - 1.8e-15 56.9 14.1 1.9e-07 30.7 1.4 3.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 EAU85489.2 - 2.6e-13 48.5 29.8 0.13 12.3 0.1 10.4 8 2 3 11 11 11 6 Leucine Rich repeat LRR_7 PF13504.1 EAU85489.2 - 5.2e-10 37.8 29.9 2.2 8.8 0.1 11.3 12 0 0 12 12 12 4 Leucine rich repeat LRR_5 PF13306.1 EAU85489.2 - 0.031 13.9 0.6 0.41 10.3 0.0 2.3 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) gag_pre-integrs PF13976.1 EAU85489.2 - 0.093 12.3 1.2 0.56 9.8 0.1 2.9 3 1 0 3 3 3 0 GAG-pre-integrase domain Myc_N PF01056.13 EAU85489.2 - 1.3 8.0 8.9 1.9 7.5 6.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region GATA PF00320.22 EAU85490.2 - 3.2e-14 51.9 4.7 6.7e-14 50.9 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 EAU85490.2 - 0.0036 17.2 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain Ank_4 PF13637.1 EAU85491.2 - 0.0016 18.9 0.0 1.7 9.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU85491.2 - 0.025 14.9 0.0 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU85491.2 - 0.079 13.2 0.0 3.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 EAU85491.2 - 0.26 11.1 1.0 3.2 7.7 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeat MaoC_dehydratas PF01575.14 EAU85494.2 - 1.1e-28 99.0 0.0 1.7e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EAU85494.2 - 1.1e-12 47.8 0.0 1.5e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase adh_short PF00106.20 EAU85495.1 - 4e-64 215.5 13.6 5e-33 114.3 1.9 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAU85495.1 - 4.7e-30 104.5 8.8 1.3e-15 57.5 0.7 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EAU85495.1 - 2.5e-11 43.8 7.8 2.8e-06 27.2 0.4 2.7 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EAU85495.1 - 2.3e-05 24.1 10.9 0.0083 15.7 1.1 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EAU85495.1 - 4.4e-05 22.6 2.4 0.0034 16.4 0.5 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding PF02629.14 EAU85495.1 - 0.0015 19.0 2.3 0.74 10.3 0.1 3.1 2 0 0 2 2 2 2 CoA binding domain Methyltransf_26 PF13659.1 EAU85495.1 - 0.0062 16.5 0.5 2.5 8.1 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase domain DHHA1 PF02272.14 EAU85495.1 - 0.11 12.2 9.0 0.37 10.5 0.9 2.5 2 0 0 2 2 2 0 DHHA1 domain Ldh_1_N PF00056.18 EAU85495.1 - 0.12 12.1 6.5 1.3 8.8 0.5 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF4161 PF13722.1 EAU85495.1 - 0.16 12.2 0.6 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) Big_1 PF02369.11 EAU85495.1 - 0.19 11.6 6.9 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) DUF543 PF04418.7 EAU85495.1 - 0.29 11.0 7.2 2.8 7.9 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Shikimate_DH PF01488.15 EAU85495.1 - 0.63 10.1 3.3 5.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cyclin_N PF00134.18 EAU85496.2 - 7.1e-42 141.9 0.4 1.3e-41 141.1 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAU85496.2 - 1.4e-25 89.5 0.0 3e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain G-gamma PF00631.17 EAU85496.2 - 0.017 14.8 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 GGL domain G-patch PF01585.18 EAU85497.1 - 5.8e-14 51.5 1.0 1.2e-13 50.6 0.7 1.5 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 EAU85497.1 - 5.4e-09 36.0 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.2 EAU85497.1 - 2.6e-06 27.1 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 DExH-box splicing factor binding site Ribosomal_60s PF00428.14 EAU85498.1 - 0.089 13.2 0.7 0.089 13.2 0.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TOM13 PF08219.6 EAU85500.1 - 5.1e-14 51.7 0.1 1.7e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Outer membrane protein TOM13 Acyl-CoA_dh_1 PF00441.19 EAU85501.1 - 1.9e-28 99.4 0.3 3.1e-28 98.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EAU85501.1 - 5.3e-20 71.0 0.1 1.2e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EAU85501.1 - 1.5e-18 65.9 1.7 2.6e-18 65.2 0.4 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EAU85501.1 - 1.2e-15 58.0 0.0 3.1e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAU85501.1 - 0.0074 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EAU85501.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_1 PF00441.19 EAU85502.1 - 1.5e-30 106.2 1.1 2.3e-30 105.6 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAU85502.1 - 7.9e-19 66.9 0.9 1.6e-18 65.9 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EAU85502.1 - 9e-18 63.8 0.0 2.3e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EAU85502.1 - 1.3e-09 38.5 0.0 4.4e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAU85502.1 - 3.3e-06 27.3 0.6 7.1e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EAU85502.1 - 0.035 13.4 0.0 6.6 6.0 0.0 2.6 2 1 1 3 3 3 0 4-hydroxyphenylacetate 3-hydroxylase N terminal LicD PF04991.8 EAU85503.1 - 0.11 12.6 0.2 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 LicD family DUF4218 PF13960.1 EAU85504.2 - 9.7e-08 31.5 0.0 4.7e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) CoA_transf_3 PF02515.12 EAU85506.2 - 6.5e-30 103.7 0.0 5.5e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 EAU85507.1 - 3.3e-30 105.1 0.3 4.8e-30 104.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAU85507.1 - 2.9e-21 74.7 0.4 6.6e-21 73.5 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EAU85507.1 - 1.5e-18 66.3 0.0 3.5e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EAU85507.1 - 7.7e-15 55.4 0.0 2.4e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EAU85507.1 - 0.00061 20.0 0.1 0.0012 19.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 EAU85508.2 - 1.4e-14 53.5 0.8 3.4e-14 52.3 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU85508.2 - 0.00042 20.1 10.3 0.00068 19.4 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_3 PF01757.17 EAU85508.2 - 0.058 12.2 0.1 0.091 11.5 0.1 1.1 1 0 0 1 1 1 0 Acyltransferase family Apolipoprotein PF01442.13 EAU85509.1 - 2.7e-06 27.0 5.5 2.7e-06 27.0 3.8 2.2 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF4366 PF14283.1 EAU85509.1 - 0.0043 16.5 0.2 0.0093 15.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) FIVAR PF07554.8 EAU85509.1 - 0.078 13.2 0.6 1.2 9.4 0.1 2.7 1 1 2 3 3 3 0 Uncharacterised Sugar-binding Domain NDUFA12 PF05071.11 EAU85509.1 - 0.1 13.0 1.1 0.23 11.9 0.0 2.1 2 1 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4100 PF13352.1 EAU85509.1 - 0.22 10.9 5.5 0.046 13.1 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4100) DUF883 PF05957.8 EAU85509.1 - 0.27 11.6 40.6 0.23 11.8 2.7 4.7 2 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Epimerase PF01370.16 EAU85510.2 - 0.024 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PV-1 PF06637.6 EAU85511.1 - 0.2 10.1 0.9 0.28 9.6 0.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PsbJ PF01788.12 EAU85511.1 - 3.8 7.1 5.2 10 5.7 3.6 1.7 1 1 0 1 1 1 0 PsbJ SH3_9 PF14604.1 EAU85512.1 - 0.00046 19.7 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAU85512.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF2370 PF10176.4 EAU85513.2 - 2.4e-64 216.8 0.2 2.4e-64 216.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) WD40 PF00400.27 EAU85514.2 - 8.6e-11 41.2 1.2 0.0016 18.2 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat SPC22 PF04573.7 EAU85515.2 - 7.3e-45 152.3 0.6 7.9e-45 152.2 0.4 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Pkinase PF00069.20 EAU85516.2 - 3.1e-55 187.1 0.0 4.5e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85516.2 - 6e-19 68.1 0.0 3.3e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EAU85516.2 - 0.097 12.0 0.1 0.26 10.6 0.1 1.7 1 1 0 1 1 1 0 RIO1 family ABC_membrane PF00664.18 EAU85519.2 - 1.8e-55 188.3 30.2 2.3e-32 112.5 5.2 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAU85519.2 - 8.9e-52 175.0 0.0 2.7e-29 102.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAU85519.2 - 7.4e-09 35.1 1.1 0.0084 15.3 0.0 3.9 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU85519.2 - 2.8e-08 34.0 1.1 0.046 13.6 0.1 4.1 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.1 EAU85519.2 - 5.5e-06 26.8 1.1 0.18 12.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EAU85519.2 - 7.3e-06 25.4 1.0 0.054 13.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EAU85519.2 - 9.1e-06 25.6 0.1 0.022 14.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EAU85519.2 - 2.1e-05 24.0 0.1 0.02 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU85519.2 - 4.1e-05 23.6 0.1 0.022 14.7 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAU85519.2 - 0.00016 22.4 2.2 0.53 11.1 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EAU85519.2 - 0.00039 19.9 0.2 0.92 8.8 0.1 2.6 2 1 0 2 2 2 2 AAA-like domain ATP_bind_1 PF03029.12 EAU85519.2 - 0.00046 19.8 2.5 3.6 7.0 0.1 3.3 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EAU85519.2 - 0.00057 19.0 0.4 0.52 9.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EAU85519.2 - 0.00063 18.8 0.9 0.41 9.7 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 EAU85519.2 - 0.00073 20.0 3.2 0.39 11.2 0.0 2.8 3 0 0 3 3 2 2 Miro-like protein AAA_18 PF13238.1 EAU85519.2 - 0.00083 19.6 0.1 3.6 7.9 0.1 3.4 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EAU85519.2 - 0.0024 17.5 1.4 0.11 12.2 0.2 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EAU85519.2 - 0.0034 17.0 1.7 0.02 14.5 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EAU85519.2 - 0.0035 17.0 0.2 0.22 11.1 0.0 3.0 3 1 0 3 3 2 1 Archaeal ATPase AAA_22 PF13401.1 EAU85519.2 - 0.0038 17.3 1.7 0.83 9.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EAU85519.2 - 0.0041 16.7 0.4 0.026 14.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.4 EAU85519.2 - 0.0049 15.5 0.9 1.4 7.4 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 EAU85519.2 - 0.0061 16.0 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain BLVR PF06375.6 EAU85519.2 - 0.012 15.4 0.3 0.028 14.2 0.2 1.6 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) ResIII PF04851.10 EAU85519.2 - 0.012 15.3 0.0 9.9 5.9 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 EAU85519.2 - 0.015 14.7 0.3 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EAU85519.2 - 0.016 14.1 0.0 2.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.14 EAU85519.2 - 0.018 14.4 1.9 0.13 11.6 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EAU85519.2 - 0.021 14.3 2.1 5.4 6.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EAU85519.2 - 0.027 14.2 0.2 0.14 11.8 0.0 2.4 2 0 0 2 2 1 0 Part of AAA domain NB-ARC PF00931.17 EAU85519.2 - 0.028 13.2 0.6 4.8 5.9 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.18 EAU85519.2 - 0.037 13.8 2.8 2.6 7.8 0.2 2.7 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.1 EAU85519.2 - 0.053 13.3 1.5 1.6 8.5 0.2 3.2 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EAU85519.2 - 0.09 12.2 0.5 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RecA PF00154.16 EAU85519.2 - 0.11 11.5 0.1 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein RNA_helicase PF00910.17 EAU85519.2 - 0.15 12.2 0.1 28 4.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.1 EAU85519.2 - 0.36 9.2 0.0 0.72 8.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EAU85519.2 - 0.41 10.4 9.0 0.076 12.8 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Actin PF00022.14 EAU85522.1 - 2e-90 303.0 0.0 2.8e-90 302.5 0.0 1.0 1 0 0 1 1 1 1 Actin UPF0061 PF02696.9 EAU85523.1 - 8.1e-97 324.5 0.0 1.1e-96 324.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family 7TMR-HDED PF07697.6 EAU85523.1 - 0.19 11.4 0.1 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 7TM-HD extracellular Pkinase PF00069.20 EAU85524.2 - 1.4e-45 155.4 0.0 2.6e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85524.2 - 4.5e-41 140.6 0.0 7e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAU85524.2 - 0.027 13.5 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU85524.2 - 0.031 14.0 1.9 0.098 12.3 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU85524.2 - 0.037 12.9 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EAU85524.2 - 0.11 11.8 0.3 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 RIO1 family DUF2945 PF11160.3 EAU85525.2 - 1.5e-23 82.3 0.1 1.9e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) HMG_box PF00505.14 EAU85526.1 - 8.5e-12 45.1 0.7 1.7e-11 44.2 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU85526.1 - 0.0041 17.4 0.1 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain ECH PF00378.15 EAU85527.1 - 8.4e-26 90.5 0.0 5.3e-25 87.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NDUFB10 PF10249.4 EAU85528.1 - 0.067 13.3 0.1 0.07 13.2 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 ThuA PF06283.6 EAU85529.2 - 2.1e-53 181.2 0.0 2.5e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Trehalose utilisation CTDII PF01556.13 EAU85530.2 - 1.9e-20 72.5 0.6 1.5e-18 66.4 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EAU85530.2 - 3e-09 36.7 21.2 5e-09 36.0 14.7 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 EAU85530.2 - 5.6e-07 29.2 0.1 1.5e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Cytochrom_c3_2 PF14537.1 EAU85530.2 - 0.71 10.2 7.4 1.5 9.1 4.8 1.8 1 1 0 1 1 1 0 Cytochrome c3 HypA PF01155.14 EAU85530.2 - 0.82 9.3 14.3 3.5 7.3 5.1 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Nol1_Nop2_Fmu PF01189.12 EAU85531.2 - 2e-17 63.4 0.0 8.3e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Fibrillarin PF01269.12 EAU85531.2 - 0.00044 19.2 0.0 0.00075 18.4 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin zf-CCHC PF00098.18 EAU85532.1 - 1.1e-11 44.0 7.7 1.6e-05 24.5 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EAU85532.1 - 1.1e-06 28.3 3.6 0.0021 17.7 1.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EAU85532.1 - 2.1e-05 24.0 0.0 4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EAU85532.1 - 0.00031 20.2 0.1 0.00076 19.0 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EAU85532.1 - 0.00081 19.0 7.4 0.19 11.4 0.6 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EAU85532.1 - 0.0012 18.4 6.1 0.27 10.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EAU85532.1 - 0.048 13.7 5.2 0.1 12.6 3.6 1.5 1 0 0 1 1 1 0 DnaJ central domain CCDC-167 PF15188.1 EAU85532.1 - 1.3 9.0 5.2 0.75 9.7 0.1 2.8 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Helicase_C_3 PF13625.1 EAU85533.1 - 1.2e-19 70.3 0.0 9e-19 67.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU85533.1 - 3.7e-15 56.2 0.0 7.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAU85533.1 - 4.3e-13 48.7 0.1 6.9e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU85533.1 - 1.5e-09 37.5 0.0 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU85533.1 - 1.9e-07 30.7 0.1 3.2e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EAU85533.1 - 0.044 12.5 0.1 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 bZIP_1 PF00170.16 EAU85534.1 - 2.1e-05 24.3 1.8 3.6e-05 23.6 1.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAU85534.1 - 0.0083 15.9 2.3 0.016 14.9 1.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HMGL-like PF00682.14 EAU85537.1 - 7.1e-72 241.8 0.8 1.2e-71 241.1 0.4 1.5 2 0 0 2 2 2 1 HMGL-like FliG_N PF14842.1 EAU85537.1 - 0.13 12.3 0.2 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Cys_Met_Meta_PP PF01053.15 EAU85539.1 - 7.5e-127 422.7 0.0 1e-126 422.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 EAU85539.1 - 2.9e-18 65.6 0.6 2.4e-17 62.7 0.2 2.8 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EAU85539.1 - 2.5e-08 33.9 0.1 9.9e-08 32.0 0.0 2.0 1 1 1 2 2 2 1 GHMP kinases C terminal Aminotran_1_2 PF00155.16 EAU85539.1 - 0.00016 20.8 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EAU85539.1 - 0.00034 19.7 0.0 0.00072 18.7 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EAU85539.1 - 0.00035 19.7 0.0 0.00074 18.7 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EAU85539.1 - 0.0028 16.0 0.0 0.0072 14.6 0.0 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase GalKase_gal_bdg PF10509.4 EAU85539.1 - 0.0032 16.7 0.0 0.0087 15.3 0.0 1.7 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GDC-P PF02347.11 EAU85539.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein Terpene_synth_C PF03936.11 EAU85540.1 - 1.2e-13 50.9 0.5 1.4e-13 50.7 0.3 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.14 EAU85541.2 - 3.2e-35 119.5 0.3 9.3e-35 118.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EAU85541.2 - 2.5e-29 101.5 0.1 4.2e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EAU85541.2 - 0.00078 19.2 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Restriction endonuclease Trigger_C PF05698.9 EAU85541.2 - 0.062 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus R3H PF01424.17 EAU85541.2 - 0.079 12.6 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 R3H domain WD40 PF00400.27 EAU85542.2 - 1.2e-22 78.8 1.2 9.8e-07 28.4 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Ras PF00071.17 EAU85544.2 - 3.1e-57 192.4 0.1 3.7e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU85544.2 - 1.1e-19 71.0 0.0 1.7e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU85544.2 - 4.5e-08 32.5 0.0 6.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU85544.2 - 4.6e-06 26.1 0.0 1e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EAU85544.2 - 0.005 16.1 0.1 0.012 14.9 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EAU85544.2 - 0.012 15.5 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EAU85544.2 - 0.2 11.1 1.2 2.5 7.5 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Mito_carr PF00153.22 EAU85546.2 - 1.2e-55 185.1 0.2 6.4e-23 80.2 0.6 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF779 PF05610.6 EAU85546.2 - 0.073 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF779) Methyltransf_16 PF10294.4 EAU85547.2 - 2.4e-22 79.2 0.0 4.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 EAU85548.2 - 1.4e-76 256.9 0.3 2.7e-76 256.0 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAU85548.2 - 1.7e-41 140.5 0.4 9.9e-41 138.0 0.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EAU85548.2 - 0.00023 20.7 0.4 0.086 12.5 0.0 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EAU85548.2 - 0.00039 19.9 0.3 0.001 18.5 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Rad51 PF08423.6 EAU85550.2 - 7.4e-12 44.7 0.0 1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 EAU85550.2 - 0.00022 20.4 0.1 0.00039 19.5 0.0 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EAU85550.2 - 0.0074 15.4 0.0 0.4 9.7 0.0 2.3 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 EAU85550.2 - 0.011 15.1 0.0 0.089 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAU85550.2 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU85550.2 - 0.039 13.9 0.2 0.19 11.7 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain DEAD PF00270.24 EAU85550.2 - 0.078 12.4 0.0 3.6 7.0 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase DnaB_C PF03796.10 EAU85550.2 - 0.084 11.7 0.0 0.38 9.5 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TauD PF02668.11 EAU85551.1 - 2.1e-55 188.2 0.1 2.6e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATA PF00320.22 EAU85552.2 - 6.2e-15 54.2 4.0 1.2e-14 53.2 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger Adaptin_N PF01602.15 EAU85554.2 - 5.7e-75 252.6 0.0 2.1e-74 250.7 0.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EAU85554.2 - 9e-06 25.3 2.2 2.2 8.5 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 EAU85554.2 - 4.7e-05 23.5 0.1 0.059 13.6 0.0 3.4 3 1 0 3 3 3 2 HEAT repeats Nop14 PF04147.7 EAU85554.2 - 0.0008 17.4 21.0 0.0016 16.4 14.6 1.5 1 0 0 1 1 1 1 Nop14-like family HEAT_EZ PF13513.1 EAU85554.2 - 0.025 15.0 0.1 6.9 7.3 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat DUF2322 PF10084.4 EAU85554.2 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) DDHD PF02862.12 EAU85554.2 - 6.2 6.5 12.5 22 4.7 8.5 1.9 2 0 0 2 2 2 0 DDHD domain Daxx PF03344.10 EAU85554.2 - 7.9 4.8 29.4 15 3.9 20.4 1.4 1 0 0 1 1 1 0 Daxx Family WD40 PF00400.27 EAU85556.1 - 0.0095 15.7 0.8 2.4 8.1 0.0 4.6 6 0 0 6 6 6 1 WD domain, G-beta repeat FliS PF02561.9 EAU85556.1 - 0.052 13.4 0.2 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 Flagellar protein FliS FH2 PF02181.18 EAU85556.1 - 0.37 9.6 2.6 0.58 8.9 1.8 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Serinc PF03348.10 EAU85557.1 - 9.1e-148 492.5 7.6 1e-147 492.3 5.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3328 PF11807.3 EAU85557.1 - 1.1 8.8 3.5 29 4.2 0.4 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF3328) FA_desaturase PF00487.19 EAU85557.1 - 9.4 5.5 16.1 8.5 5.7 5.9 3.1 2 1 1 3 3 3 0 Fatty acid desaturase RRM_1 PF00076.17 EAU85560.1 - 1e-15 57.1 0.0 2.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU85560.1 - 9.1e-11 41.5 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU85560.1 - 1.4e-08 34.4 0.1 2.4e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4559 PF15112.1 EAU85561.1 - 0.046 12.8 0.4 0.079 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) MBOAT_2 PF13813.1 EAU85562.1 - 3.2e-17 62.3 3.5 3.2e-17 62.3 2.4 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Methyltransf_25 PF13649.1 EAU85563.2 - 3.5e-06 27.3 0.0 4.6e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Maf1 PF09174.5 EAU85564.1 - 1.1e-39 136.1 0.9 2.5e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 Maf1 regulator Pectate_lyase PF03211.8 EAU85565.2 - 1.2e-54 185.0 0.0 1.3e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Pectate lyase Pectate_lyase PF03211.8 EAU85566.1 - 4.3e-66 222.3 2.4 5.7e-66 221.9 1.7 1.1 1 0 0 1 1 1 1 Pectate lyase TPR_11 PF13414.1 EAU85567.2 - 2.2e-28 97.6 8.8 1.3e-11 43.9 0.1 6.2 6 0 0 6 6 6 4 TPR repeat TPR_2 PF07719.12 EAU85567.2 - 1.5e-27 93.2 14.4 2.2e-06 27.1 0.0 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EAU85567.2 - 2.5e-25 88.4 8.9 3.2e-09 36.7 0.0 6.0 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EAU85567.2 - 2e-21 74.6 8.1 2.3e-07 30.1 0.0 6.7 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EAU85567.2 - 3.8e-18 63.8 3.3 0.00012 21.6 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAU85567.2 - 2.3e-17 63.1 15.2 1.1e-09 38.6 0.1 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAU85567.2 - 2.8e-17 62.7 4.2 5.7e-05 23.3 0.2 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAU85567.2 - 5.3e-17 61.5 16.9 1.2e-10 41.1 0.2 7.0 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU85567.2 - 5.2e-12 44.6 5.9 0.00015 21.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAU85567.2 - 1.6e-11 43.7 13.0 0.012 16.1 0.0 7.6 5 1 3 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAU85567.2 - 1e-09 37.7 12.2 0.004 17.2 0.0 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAU85567.2 - 7.5e-08 32.0 13.0 0.0012 18.7 0.0 5.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EAU85567.2 - 9.2e-08 32.0 14.8 0.27 11.7 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAU85567.2 - 7.4e-05 22.5 2.0 0.0093 15.8 0.0 4.3 4 1 1 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 EAU85567.2 - 0.0011 18.7 0.4 15 5.8 0.0 3.9 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.9 EAU85567.2 - 0.027 14.8 1.7 19 6.0 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.4 EAU85567.2 - 0.032 13.6 0.4 0.9 8.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.1 EAU85567.2 - 0.036 13.9 17.0 0.8 9.5 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat eIF-1a PF01176.14 EAU85568.2 - 9e-29 98.6 0.2 1.3e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ank_2 PF12796.2 EAU85569.2 - 4.6e-12 46.1 0.2 7.8e-08 32.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAU85569.2 - 4.6e-06 26.3 0.0 0.28 11.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EAU85569.2 - 6.3e-06 26.2 0.0 0.22 11.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EAU85569.2 - 1.2e-05 24.8 0.0 4.2 7.3 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EAU85569.2 - 0.0013 19.1 0.3 0.028 14.9 0.0 2.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF3447 PF11929.3 EAU85569.2 - 0.089 12.6 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) DUF2034 PF10356.4 EAU85569.2 - 0.11 11.7 0.1 0.26 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) YhhN PF07947.9 EAU85571.1 - 7.3e-26 90.6 11.6 9.7e-23 80.4 3.9 2.5 2 1 0 2 2 2 2 YhhN-like protein DUF3493 PF11998.3 EAU85571.1 - 0.089 12.6 0.1 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) DHDPS PF00701.17 EAU85572.2 - 2e-40 138.2 0.0 3.5e-40 137.4 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2070 PF09843.4 EAU85572.2 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Dynamin_N PF00350.18 EAU85573.1 - 5.6e-42 143.4 0.0 1.2e-41 142.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EAU85573.1 - 1.7e-08 33.5 0.0 5.3e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EAU85573.1 - 0.0025 17.7 0.0 0.0069 16.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EAU85573.1 - 0.0049 17.3 0.1 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EAU85573.1 - 0.0062 16.5 0.3 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SCP2 PF02036.12 EAU85574.2 - 2e-24 85.7 1.1 2.5e-24 85.5 0.8 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EAU85574.2 - 6.3e-06 26.1 1.3 9.3e-06 25.6 0.9 1.3 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal Big_2 PF02368.13 EAU85574.2 - 0.029 14.2 0.7 0.049 13.5 0.5 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) CelD_N PF02927.9 EAU85574.2 - 0.13 12.4 0.5 0.3 11.3 0.4 1.9 1 1 0 1 1 1 0 N-terminal ig-like domain of cellulase AAA_12 PF13087.1 EAU85577.1 - 1.1e-34 119.5 0.1 2.8e-34 118.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU85577.1 - 4.1e-26 91.9 0.2 4.4e-24 85.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAU85577.1 - 1.6e-14 53.9 0.0 9e-14 51.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU85577.1 - 1.1e-10 41.0 0.0 6.5e-10 38.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EAU85577.1 - 7.6e-07 28.8 0.3 0.018 14.5 0.0 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EAU85577.1 - 2.9e-05 24.1 0.1 0.00037 20.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EAU85577.1 - 3.1e-05 23.1 0.0 0.0016 17.5 0.0 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EAU85577.1 - 0.00019 21.1 0.0 0.00067 19.3 0.0 2.0 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.1 EAU85577.1 - 0.00068 19.6 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 EAU85577.1 - 0.00086 18.8 0.1 0.0032 16.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.24 EAU85577.1 - 0.0029 17.8 0.0 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EAU85577.1 - 0.0048 16.1 0.0 0.058 12.6 0.0 2.3 1 1 0 1 1 1 1 PhoH-like protein AAA_17 PF13207.1 EAU85577.1 - 0.0062 17.3 0.0 0.018 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EAU85577.1 - 0.0069 15.3 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EAU85577.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EAU85577.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAU85577.1 - 0.017 13.9 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EAU85577.1 - 0.026 14.0 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EAU85577.1 - 0.056 13.7 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EAU85577.1 - 0.074 12.1 0.3 0.33 10.0 0.0 2.3 2 1 0 2 2 2 0 KaiC AAA_23 PF13476.1 EAU85577.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EAU85577.1 - 0.13 11.5 0.0 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_12 PF13087.1 EAU85578.2 - 7.7e-36 123.3 0.4 1.3e-35 122.5 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU85578.2 - 8.8e-19 68.0 0.0 2.3e-11 43.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EAU85578.2 - 6e-15 55.3 0.0 1.7e-14 53.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU85578.2 - 2.5e-09 36.7 0.1 1.1e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EAU85578.2 - 2.3e-05 24.0 0.1 0.0062 16.0 0.0 2.8 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EAU85578.2 - 0.00051 19.3 0.0 0.034 13.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Helicase_RecD PF05127.9 EAU85578.2 - 0.0011 18.6 0.0 0.0031 17.1 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF2075 PF09848.4 EAU85578.2 - 0.0021 17.0 0.7 0.2 10.5 0.1 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EAU85578.2 - 0.0023 17.9 0.0 0.0057 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 EAU85578.2 - 0.0083 15.6 0.1 0.021 14.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU85578.2 - 0.0099 16.0 0.0 0.059 13.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain Shugoshin_C PF07557.6 EAU85578.2 - 0.068 12.6 0.2 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Shugoshin C terminus Carn_acyltransf PF00755.15 EAU85579.2 - 1.3e-125 419.8 0.0 1.5e-125 419.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase XPG_I PF00867.13 EAU85580.2 - 6.3e-28 96.6 0.0 2.4e-27 94.8 0.0 2.1 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAU85580.2 - 3.8e-22 78.4 0.0 9.5e-22 77.1 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EAU85580.2 - 0.0028 17.1 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing Reovirus_L2 PF06016.6 EAU85580.2 - 0.085 9.8 0.0 0.13 9.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) OGFr_N PF04664.8 EAU85580.2 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region CtaG_Cox11 PF04442.9 EAU85581.2 - 9.3e-57 191.0 0.1 1.2e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.26 EAU85582.1 - 1.3e-15 56.8 0.8 1.3e-15 56.8 0.6 2.4 3 0 0 3 3 3 1 DnaJ domain MutS_III PF05192.13 EAU85582.1 - 0.14 11.9 2.7 0.21 11.3 1.8 1.3 1 0 0 1 1 1 0 MutS domain III PfkB PF00294.19 EAU85584.1 - 6e-13 48.5 0.0 1.3e-07 31.0 0.0 3.1 3 0 0 3 3 3 3 pfkB family carbohydrate kinase SH3_1 PF00018.23 EAU85585.1 - 1.4e-13 49.9 0.4 2.1e-13 49.4 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU85585.1 - 3.7e-12 45.6 0.1 6.3e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU85585.1 - 2.6e-11 42.8 0.0 4.3e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 EAU85585.1 - 5.3 7.0 7.1 1.4 8.9 2.5 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) APG6 PF04111.7 EAU85586.2 - 0.27 10.2 6.5 0.55 9.2 4.5 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EAU85586.2 - 0.27 9.8 7.0 0.53 8.8 4.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.5 EAU85586.2 - 0.45 10.6 8.7 0.054 13.6 3.1 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Nup88 PF10168.4 EAU85586.2 - 0.86 7.3 8.6 1.2 6.8 6.0 1.1 1 0 0 1 1 1 0 Nuclear pore component FliJ PF02050.11 EAU85586.2 - 2.9 7.9 11.9 5.7 7.0 3.4 2.6 2 0 0 2 2 2 0 Flagellar FliJ protein DUF342 PF03961.8 EAU85586.2 - 6.1 5.1 10.4 4.5 5.5 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) SKG6 PF08693.5 EAU85587.2 - 0.11 11.8 1.8 0.28 10.5 1.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Voldacs PF03517.8 EAU85588.1 - 4.4e-30 104.2 0.3 4.4e-30 104.2 0.2 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling PI3Ka PF00613.15 EAU85589.2 - 3.3e-55 186.1 0.1 5.2e-55 185.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EAU85589.2 - 1.5e-43 148.9 0.0 5.9e-42 143.7 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EAU85589.2 - 9e-40 135.7 0.0 1.4e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Aminotran_3 PF00202.16 EAU85590.2 - 2e-44 151.8 0.0 1.9e-43 148.6 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EAU85590.2 - 3.2e-28 98.7 0.0 5.5e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EAU85590.2 - 0.0043 16.4 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain TFIIA PF03153.8 EAU85591.2 - 2.8 7.7 8.3 4.9 6.9 5.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IlvN PF07991.7 EAU85592.1 - 3.3e-46 156.6 0.0 1.9e-45 154.1 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EAU85592.1 - 6.4e-42 142.9 0.0 9.1e-42 142.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TauD PF02668.11 EAU85593.1 - 2.4e-40 138.8 0.0 5e-40 137.8 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EAU85593.1 - 4.7e-09 36.5 0.0 1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 EAU85593.1 - 0.012 14.5 0.0 0.038 12.9 0.0 1.7 2 0 0 2 2 2 0 CsiD DUF2973 PF11189.3 EAU85596.2 - 0.13 12.0 1.4 1.4 8.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Telomere_Sde2 PF13019.1 EAU85597.1 - 3.9e-54 182.7 0.0 3.9e-54 182.7 0.0 1.7 2 0 0 2 2 2 1 Telomere stability and silencing AIG2 PF06094.7 EAU85598.2 - 1.5e-12 47.9 0.0 1.9e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family Na_Ca_ex PF01699.19 EAU85600.2 - 3.1e-31 107.8 22.1 2.3e-18 66.1 8.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.1 EAU85600.2 - 0.097 12.5 0.1 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 YWFCY protein RNA_pol_Rpc34 PF05158.7 EAU85605.2 - 8e-36 123.8 0.0 9.3e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit MarR_2 PF12802.2 EAU85605.2 - 0.0045 16.6 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 MarR family Rrf2 PF02082.15 EAU85605.2 - 0.0074 16.3 0.8 0.015 15.3 0.1 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_27 PF13463.1 EAU85605.2 - 0.064 13.5 0.1 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_IclR PF09339.5 EAU85605.2 - 0.12 11.9 0.4 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 IclR helix-turn-helix domain HSP20 PF00011.16 EAU85606.2 - 2.6e-06 27.2 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family tRNA-synt_1g PF09334.6 EAU85609.1 - 3e-125 417.9 0.5 6e-124 413.6 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 EAU85609.1 - 1.1e-06 28.1 4.2 2.6e-06 26.9 2.9 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 EAU85609.1 - 9.1e-05 20.6 0.0 0.00055 18.0 0.0 2.1 2 1 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAU85609.1 - 0.0025 17.5 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA UPF0547 PF10571.4 EAU85609.1 - 1.8 8.3 5.9 0.19 11.4 0.3 2.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Cellulase PF00150.13 EAU85611.2 - 2.9e-39 134.9 0.1 4.9e-32 111.2 0.7 2.1 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EAU85611.2 - 4.8e-11 42.1 12.1 4.8e-11 42.1 8.4 2.6 4 0 0 4 4 4 1 Fungal cellulose binding domain YrbL-PhoP_reg PF10707.4 EAU85611.2 - 0.051 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MFS_1 PF07690.11 EAU85612.2 - 1.3e-10 40.6 25.8 3.5e-08 32.5 12.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4013 PF13197.1 EAU85612.2 - 0.0065 15.8 3.6 0.15 11.4 0.1 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF4013) DUF2615 PF11027.3 EAU85612.2 - 0.17 11.7 0.0 1.9 8.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) F-box-like PF12937.2 EAU85613.2 - 1.1e-08 34.6 1.6 6.2e-08 32.2 0.2 2.6 2 0 0 2 2 2 1 F-box-like Pheromone PF08015.6 EAU85615.2 - 0.6 10.9 0.0 0.6 10.9 0.0 4.7 4 0 0 4 4 4 0 Fungal mating-type pheromone adh_short PF00106.20 EAU85616.1 - 4.5e-26 91.7 6.1 7.4e-26 91.0 4.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU85616.1 - 7.7e-24 84.7 0.8 9.8e-24 84.4 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAU85616.1 - 4.3e-06 26.8 0.8 9.3e-06 25.7 0.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EAU85616.1 - 1.7e-05 24.6 5.1 0.00012 21.7 3.5 2.0 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAU85616.1 - 5.2e-05 22.9 0.7 5.2e-05 22.9 0.5 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EAU85616.1 - 0.00076 18.9 0.1 0.0011 18.4 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GGGtGRT PF14057.1 EAU85616.1 - 0.009 14.8 0.2 0.011 14.5 0.1 1.1 1 0 0 1 1 1 1 GGGtGRT protein Methyltransf_23 PF13489.1 EAU85617.1 - 0.0029 17.3 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU85617.1 - 0.043 13.4 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain ATP_synt_H PF05493.8 EAU85618.1 - 3.2e-19 68.7 4.4 3.9e-19 68.4 3.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 EAU85618.1 - 0.0078 16.0 1.3 0.12 12.2 0.1 2.0 2 0 0 2 2 2 1 Haemopoietic lineage transmembrane helix FliP PF00813.15 EAU85618.1 - 0.01 15.5 1.2 0.011 15.4 0.9 1.0 1 0 0 1 1 1 0 FliP family DUF4131 PF13567.1 EAU85618.1 - 0.095 12.1 2.0 0.1 11.9 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1772 PF08592.6 EAU85618.1 - 0.099 12.3 3.3 0.1 12.3 2.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) YrhC PF14143.1 EAU85618.1 - 0.75 9.7 4.7 2.3 8.2 0.4 2.0 1 1 1 2 2 2 0 YrhC-like protein p450 PF00067.17 EAU85619.1 - 2.2e-72 244.0 0.5 2.4e-71 240.6 0.4 2.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU85621.2 - 3.7e-56 190.5 0.0 5.5e-55 186.7 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Alpha_kinase PF02816.13 EAU85624.1 - 0.0006 19.5 0.0 0.00078 19.1 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Citrate_synt PF00285.16 EAU85625.2 - 1.8e-26 92.7 0.0 2.2e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Peptidase_M24 PF00557.19 EAU85629.2 - 2.6e-18 66.3 0.6 3.9e-18 65.7 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_25 PF13649.1 EAU85630.2 - 2.3e-07 31.0 0.0 5.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU85630.2 - 7.6e-07 29.7 0.0 3e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU85630.2 - 1.5e-06 27.9 0.0 2.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU85630.2 - 2.5e-06 27.8 0.0 5.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU85630.2 - 4.7e-06 26.4 0.0 9.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU85630.2 - 0.00018 21.5 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU85630.2 - 0.00026 20.2 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EAU85630.2 - 0.0037 17.6 0.0 0.038 14.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAU85630.2 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EAU85630.2 - 0.017 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_15 PF09445.5 EAU85630.2 - 0.036 13.6 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase FtsJ PF01728.14 EAU85630.2 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EAU85630.2 - 0.21 10.7 0.0 0.61 9.1 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NDUF_B8 PF05821.6 EAU85631.2 - 0.00066 19.3 0.0 0.00095 18.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pex14_N PF04695.8 EAU85631.2 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ODV-E18 PF10717.4 EAU85632.2 - 0.0093 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 PsbJ PF01788.12 EAU85632.2 - 0.15 11.6 0.1 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 PsbJ PH_9 PF15410.1 EAU85633.2 - 0.0082 16.3 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain K_channel_TID PF07941.6 EAU85633.2 - 0.28 11.4 7.9 0.39 10.9 0.2 3.3 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain NOA36 PF06524.7 EAU85633.2 - 3.8 6.6 5.3 7.5 5.7 3.7 1.4 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EAU85633.2 - 6 6.3 9.7 0.25 10.8 2.5 1.8 2 0 0 2 2 2 0 Nucleoplasmin DnaJ PF00226.26 EAU85634.2 - 2.1e-17 62.5 0.0 4.6e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain cobW PF02492.14 EAU85635.2 - 2.2e-36 124.9 0.0 2.9e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EAU85635.2 - 0.012 15.3 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1574 PF07611.6 EAU85635.2 - 0.061 12.1 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Pox_A32 PF04665.7 EAU85635.2 - 0.15 11.2 0.3 0.51 9.6 0.0 1.9 3 0 0 3 3 3 0 Poxvirus A32 protein Frag1 PF10277.4 EAU85636.2 - 7.1e-12 45.2 0.3 7.1e-12 45.2 0.2 3.1 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EAU85636.2 - 0.00021 21.3 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRF PF01765.14 EAU85637.2 - 1.1e-28 99.7 1.2 1.5e-28 99.3 0.1 1.8 1 1 1 2 2 2 1 Ribosome recycling factor Sas10 PF09368.5 EAU85637.2 - 0.41 10.8 7.8 0.18 11.9 0.6 2.7 2 1 1 3 3 3 0 Sas10 C-terminal domain Peptidase_C14 PF00656.17 EAU85638.2 - 9.7e-12 45.1 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain DDE_3 PF13358.1 EAU85642.2 - 1.4e-07 31.4 0.0 4.1e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 DDE superfamily endonuclease RRM_6 PF14259.1 EAU85647.1 - 2.1e-11 43.6 0.0 3.5e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU85647.1 - 6.1e-11 41.7 1.3 9.4e-11 41.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU85647.1 - 0.0099 15.7 0.2 0.047 13.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 EAU85649.2 - 3e-07 30.0 11.2 5.7e-07 29.1 7.7 1.5 1 0 0 1 1 1 1 PHD-finger WHIM2 PF15613.1 EAU85649.2 - 0.015 15.2 0.2 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 5_nucleotid PF05761.9 EAU85649.2 - 5.7 5.3 6.2 9.4 4.6 4.3 1.3 1 0 0 1 1 1 0 5' nucleotidase family APC10 PF03256.11 EAU85650.2 - 1.8e-43 148.4 0.0 2.2e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EAU85650.2 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.5 1 1 0 1 1 1 1 F5/8 type C domain ThiF PF00899.16 EAU85651.2 - 1.1e-37 128.8 0.0 1.9e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EAU85651.2 - 1e-27 95.5 0.0 2.2e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EAU85651.2 - 9.2e-11 42.0 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EAU85651.2 - 0.00039 20.5 0.1 0.0064 16.5 0.0 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase UBX PF00789.15 EAU85652.1 - 1.8e-12 47.1 0.2 2.9e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 UBX domain PITH PF06201.8 EAU85653.2 - 1.1e-41 142.1 0.0 1.4e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Med25_VWA PF11265.3 EAU85654.2 - 0.003 16.6 0.0 0.011 14.7 0.0 1.9 1 1 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A LUC7 PF03194.10 EAU85654.2 - 0.09 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus YchF-GTPase_C PF06071.8 EAU85656.2 - 1.9e-36 123.6 0.0 4.4e-36 122.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EAU85656.2 - 3.2e-14 52.8 0.0 9.6e-14 51.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU85656.2 - 3.6e-05 23.0 0.0 6.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EAU85656.2 - 0.016 16.0 0.2 0.14 12.9 0.1 2.6 1 1 0 1 1 1 0 AAA domain BetaGal_dom3 PF13363.1 EAU85656.2 - 0.042 13.2 0.4 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 Dynamin_N PF00350.18 EAU85656.2 - 0.11 12.3 0.0 10 5.8 0.1 2.5 1 1 1 2 2 2 0 Dynamin family MMtag PF10159.4 EAU85657.2 - 9.4e-31 105.6 4.2 9.4e-31 105.6 2.9 3.2 2 1 0 2 2 2 1 Kinase phosphorylation protein OCC1 PF15506.1 EAU85657.2 - 1 9.2 5.0 1.2 9.0 1.6 2.4 2 0 0 2 2 2 0 OCC1 family DUF2215 PF10225.4 EAU85657.2 - 1.1 8.6 5.8 0.78 9.1 2.8 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2215) DUF4407 PF14362.1 EAU85657.2 - 4.3 6.2 15.5 5 5.9 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-C2H2 PF00096.21 EAU85660.1 - 3.6e-10 39.5 12.3 6.4e-05 23.0 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU85660.1 - 5.9e-08 32.6 9.3 1.1e-06 28.6 0.5 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU85660.1 - 1.8e-06 27.8 11.3 0.0011 19.1 1.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU85660.1 - 2.9e-05 24.0 7.6 0.048 13.8 1.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU85660.1 - 0.0017 18.4 8.8 0.48 10.7 2.5 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAU85660.1 - 0.026 14.4 5.5 0.26 11.2 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.6 EAU85660.1 - 0.17 11.5 4.6 2.3 8.0 1.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HC_2 PF13913.1 EAU85660.1 - 0.18 11.5 5.2 0.096 12.3 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 EAU85660.1 - 0.53 10.6 11.2 0.059 13.6 1.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EAU85660.1 - 0.77 9.9 7.5 0.39 10.8 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EAU85661.2 - 7.2e-10 38.6 12.3 0.0002 21.5 2.4 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EAU85661.2 - 3.2e-07 30.2 5.4 0.0014 18.6 0.9 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EAU85661.2 - 4.4e-07 29.8 2.9 0.00027 21.0 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU85661.2 - 2.4e-06 27.4 9.7 0.0086 16.3 0.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EAU85661.2 - 0.015 14.9 1.0 0.015 14.9 0.7 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SprT-like PF10263.4 EAU85661.2 - 0.037 13.6 1.1 0.09 12.4 0.7 1.6 1 0 0 1 1 1 0 SprT-like family zf-met PF12874.2 EAU85661.2 - 0.041 14.1 7.7 0.33 11.2 0.8 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAU85661.2 - 1.8 8.7 6.2 10 6.2 1.1 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Glyco_hydro_cc PF11790.3 EAU85663.1 - 1.7e-48 165.1 0.0 2.2e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ERG4_ERG24 PF01222.12 EAU85665.2 - 1.4e-137 458.8 4.5 1.6e-137 458.6 3.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EAU85665.2 - 0.00027 20.3 0.1 0.00058 19.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EAU85665.2 - 0.0053 16.8 0.3 0.03 14.4 0.0 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EAU85665.2 - 0.034 14.3 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Acetate_kinase PF00871.12 EAU85667.2 - 1.5e-86 290.4 0.0 1.2e-85 287.3 0.0 2.0 1 1 0 1 1 1 1 Acetokinase family DUF1464 PF07318.7 EAU85667.2 - 0.02 13.7 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) XFP_N PF09364.5 EAU85668.1 - 2.3e-158 526.7 0.0 2.9e-158 526.3 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EAU85668.1 - 1.6e-68 229.8 0.0 2.6e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EAU85668.1 - 3.5e-68 229.0 0.0 7.8e-68 227.8 0.0 1.5 2 0 0 2 2 2 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EAU85668.1 - 0.0033 17.0 0.2 0.0075 15.8 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Nucleoporin_FG PF13634.1 EAU85669.1 - 3e-40 136.9 173.6 5.9e-13 49.0 31.0 4.7 1 1 3 4 4 4 4 Nucleoporin FG repeat region Mitofilin PF09731.4 EAU85671.1 - 2.7e-116 389.5 22.4 3.8e-116 389.0 15.5 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF2461 PF09365.5 EAU85671.1 - 0.33 10.3 3.7 0.1 11.9 0.4 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) PRiA4_ORF3 PF07929.6 EAU85675.2 - 1.8e-18 66.6 0.1 2.7e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.13 EAU85675.2 - 2.2e-11 43.4 10.8 3.5e-11 42.7 7.5 1.4 1 0 0 1 1 1 1 MYND finger Med22 PF06179.7 EAU85676.1 - 1.2e-17 63.9 2.6 1.7e-17 63.4 1.8 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF2075 PF09848.4 EAU85676.1 - 0.067 12.1 0.6 0.074 12.0 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PMC2NT PF08066.7 EAU85676.1 - 0.11 12.7 2.3 1 9.6 0.1 2.3 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DnaJ-X PF14308.1 EAU85676.1 - 0.28 10.4 4.3 5.9 6.1 3.0 2.2 1 1 0 1 1 1 0 X-domain of DnaJ-containing COG5 PF10392.4 EAU85678.1 - 0.091 12.7 4.2 4.5 7.2 0.1 2.6 3 0 0 3 3 3 0 Golgi transport complex subunit 5 PB1 PF00564.19 EAU85679.1 - 0.0033 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain PX PF00787.19 EAU85679.1 - 0.0072 16.1 0.1 0.045 13.5 0.0 2.3 1 1 0 1 1 1 1 PX domain Actin PF00022.14 EAU85680.2 - 2.7e-43 147.8 0.0 2.9e-42 144.5 0.0 2.3 1 1 0 1 1 1 1 Actin Alpha_kinase PF02816.13 EAU85681.1 - 0.00011 21.9 0.3 0.00011 21.9 0.2 1.5 2 0 0 2 2 2 1 Alpha-kinase family Syntaxin_2 PF14523.1 EAU85684.2 - 0.088 12.8 0.1 22 5.1 0.0 2.8 2 1 0 2 2 2 0 Syntaxin-like protein zf-CCHC_4 PF14392.1 EAU85686.1 - 0.00012 21.6 4.2 0.015 14.9 0.4 2.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 EAU85686.1 - 0.00064 19.5 7.8 0.16 11.9 0.6 2.2 2 0 0 2 2 2 2 Zinc knuckle C1_1 PF00130.17 EAU85686.1 - 0.075 12.7 2.4 0.11 12.1 1.7 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UBN2_2 PF14227.1 EAU85691.2 - 2.5e-05 23.8 0.0 5.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 EAU85691.2 - 0.0044 16.6 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain Pkinase PF00069.20 EAU85693.2 - 3e-06 26.5 0.0 4.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU85693.2 - 3.8e-05 23.5 0.3 0.00015 21.6 0.2 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU85693.2 - 0.00027 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EAU85693.2 - 0.01 14.9 0.0 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FtsK_SpoIIIE PF01580.13 EAU85703.2 - 0.0017 17.8 0.0 0.1 12.0 0.0 2.3 2 1 0 2 2 2 2 FtsK/SpoIIIE family Vps5 PF09325.5 EAU85703.2 - 0.11 11.6 0.4 0.88 8.7 0.0 2.0 2 0 0 2 2 2 0 Vps5 C terminal like GMC_oxred_N PF00732.14 EAU85704.2 - 6.5e-70 235.6 0.4 8.3e-70 235.2 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU85704.2 - 3.8e-31 108.3 0.0 6.5e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU85704.2 - 2.4e-05 24.2 0.0 0.00035 20.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU85704.2 - 3.5e-05 22.8 1.9 0.00021 20.2 1.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAU85704.2 - 7.1e-05 21.8 0.1 0.0081 15.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EAU85704.2 - 9.9e-05 21.4 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EAU85704.2 - 0.0007 19.5 0.1 0.04 13.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1471 PF07338.8 EAU85704.2 - 0.0098 15.5 0.1 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) TrkA_N PF02254.13 EAU85704.2 - 0.063 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EAU85704.2 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 EAU85705.1 - 2.7e-66 223.7 0.0 3.7e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU85705.1 - 1.2e-07 32.1 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU85706.1 - 1.1e-14 54.9 0.1 1.1e-14 54.8 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase DUF605 PF04652.11 EAU85708.1 - 2.9 7.2 8.9 3 7.1 6.2 1.1 1 0 0 1 1 1 0 Vta1 like Med15 PF09606.5 EAU85708.1 - 8.3 4.4 24.5 9.9 4.2 17.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glyoxalase_2 PF12681.2 EAU85709.1 - 8.2e-09 36.0 0.0 1e-08 35.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EAU85709.1 - 0.00075 19.4 0.0 0.0024 17.8 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tudor-knot PF11717.3 EAU85709.1 - 0.035 13.8 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain TFIIA PF03153.8 EAU85710.2 - 0.02 14.7 0.3 0.02 14.7 0.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.1 EAU85710.2 - 0.13 12.6 0.1 0.13 12.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 EAU85711.1 - 2.4e-05 24.2 5.4 0.0091 16.1 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EAU85711.1 - 0.0027 17.9 8.1 0.4 11.1 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU85711.1 - 0.0055 16.9 0.2 0.0055 16.9 0.1 3.1 2 1 1 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EAU85711.1 - 0.0071 16.6 1.0 0.0071 16.6 0.7 2.7 2 1 0 2 2 2 1 Zinc finger, C2H2 type DUF3505 PF12013.3 EAU85711.1 - 1.2 9.4 7.8 2.5 8.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3505) Ribosomal_L23eN PF03939.8 EAU85713.2 - 1e-19 70.2 10.0 1e-19 70.2 7.0 3.2 3 2 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EAU85713.2 - 9.1e-19 67.2 2.3 2.1e-18 66.0 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 Macoilin PF09726.4 EAU85713.2 - 1.6 6.8 7.0 1.9 6.6 4.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Med3 PF11593.3 EAU85713.2 - 3.3 6.8 9.9 5 6.2 6.8 1.3 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.2 EAU85721.2 - 0.0046 16.6 0.9 0.011 15.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like BTB PF00651.26 EAU85722.2 - 4.4e-10 39.5 0.0 9.2e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3006 PF11213.3 EAU85722.2 - 0.046 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Transket_pyr PF02779.19 EAU85723.2 - 1.7e-65 219.8 0.0 2.6e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EAU85723.2 - 5.8e-58 195.9 0.0 8.9e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component F-box-like PF12937.2 EAU85724.2 - 0.0027 17.3 0.0 0.0078 15.9 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU85725.1 - 8.8e-05 22.1 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU85730.1 - 0.0029 17.2 1.2 0.0095 15.6 0.3 2.4 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU85731.1 - 8.3e-05 22.2 1.8 0.00013 21.5 0.1 2.3 2 1 0 2 2 2 1 F-box-like Ank_2 PF12796.2 EAU85732.2 - 4.8e-33 113.3 0.0 6.7e-13 48.7 0.0 6.1 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU85732.2 - 1.9e-29 101.0 2.1 4.3e-08 33.1 0.0 7.9 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU85732.2 - 3.4e-29 100.6 0.4 6.2e-10 39.3 0.0 7.0 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU85732.2 - 2.6e-23 79.7 0.0 0.017 15.2 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.25 EAU85732.2 - 7.8e-23 79.0 2.7 0.0037 17.0 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat AAA_16 PF13191.1 EAU85732.2 - 0.00013 21.9 0.0 0.00041 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EAU85732.2 - 0.00015 21.4 0.0 0.00041 20.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU85732.2 - 0.00053 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAU85732.2 - 0.0051 15.6 0.0 0.16 10.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 EAU85732.2 - 0.033 13.1 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) adh_short PF00106.20 EAU85733.2 - 4.6e-26 91.7 2.7 1.4e-15 57.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EAU85733.2 - 2.4e-08 34.0 0.1 0.0065 16.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU85733.2 - 8.6e-06 25.5 1.4 0.0017 18.0 0.2 2.2 2 0 0 2 2 2 2 KR domain TerB-C PF15615.1 EAU85733.2 - 0.083 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TerB-C domain MbeD_MobD PF04899.7 EAU85736.2 - 0.11 12.3 8.8 0.71 9.8 1.8 2.5 1 1 1 2 2 2 0 MbeD/MobD like DUF904 PF06005.7 EAU85736.2 - 0.3 11.4 9.3 0.27 11.5 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF3552 PF12072.3 EAU85736.2 - 1.1 8.4 20.6 0.036 13.2 10.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) GAS PF13851.1 EAU85736.2 - 1.5 7.9 10.1 0.97 8.5 5.3 1.9 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 EAU85736.2 - 2.9 8.3 7.2 0.48 10.8 1.4 2.4 2 0 0 2 2 2 0 SlyX Pilin PF00114.14 EAU85736.2 - 3.8 8.2 11.8 0.78 10.4 5.4 2.0 1 1 1 2 2 2 0 Pilin (bacterial filament) Seryl_tRNA_N PF02403.17 EAU85736.2 - 4.5 7.3 11.1 8.9 6.3 4.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_12 PF13424.1 EAU85739.2 - 7.9e-10 38.5 0.2 6.1e-06 26.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 EAU85739.2 - 2.9e-07 29.6 0.0 1.5e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 EAU85739.2 - 1e-06 28.5 0.0 3.1e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.12 EAU85739.2 - 1.6e-05 24.4 5.1 2.6 8.1 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.1 EAU85739.2 - 0.00028 21.0 0.0 0.0028 17.7 0.0 2.7 2 1 1 3 3 3 1 AAA domain TPR_11 PF13414.1 EAU85739.2 - 0.00039 19.9 0.8 0.066 12.8 0.0 3.2 3 0 0 3 3 3 1 TPR repeat Baculo_PEP_C PF04513.7 EAU85739.2 - 0.00066 19.5 2.2 0.0019 18.0 0.6 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_16 PF13191.1 EAU85739.2 - 0.0013 18.7 0.1 0.015 15.2 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EAU85739.2 - 0.015 15.4 0.0 0.084 13.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TPR_14 PF13428.1 EAU85739.2 - 0.059 14.0 0.4 18 6.2 0.0 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU85739.2 - 0.059 12.9 1.3 7.1 6.4 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 EAU85739.2 - 0.14 12.4 2.7 0.32 11.3 0.1 3.0 3 0 0 3 3 3 0 Snapin/Pallidin NPV_P10 PF05531.7 EAU85739.2 - 0.4 10.9 6.3 2 8.7 0.3 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein NCA2 PF08637.5 EAU85740.2 - 2.4e-64 217.0 0.0 8.3e-55 185.7 0.0 3.1 2 1 0 2 2 2 2 ATP synthase regulation protein NCA2 TPR_12 PF13424.1 EAU85741.1 - 3.2e-11 43.0 0.5 1e-06 28.5 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 EAU85741.1 - 3.2e-06 27.2 0.5 0.00054 20.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain TPR_11 PF13414.1 EAU85741.1 - 4.5e-05 23.0 0.8 0.00036 20.1 0.0 2.8 3 0 0 3 3 3 1 TPR repeat NACHT PF05729.7 EAU85741.1 - 0.00036 20.2 0.0 0.0013 18.4 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU85741.1 - 0.00048 20.2 0.0 0.0026 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAU85741.1 - 0.00061 18.7 0.0 0.0016 17.3 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain SNAP PF14938.1 EAU85741.1 - 0.00071 18.8 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP AAA PF00004.24 EAU85741.1 - 0.00083 19.5 0.0 0.003 17.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_2 PF07719.12 EAU85741.1 - 0.062 13.2 1.0 3.8 7.6 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FANCI_S2 PF14676.1 EAU85741.1 - 0.074 12.9 0.2 0.21 11.4 0.2 1.8 1 0 0 1 1 1 0 FANCI solenoid 2 DUF953 PF06110.6 EAU85741.1 - 0.15 11.5 0.0 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) TPR_1 PF00515.23 EAU85741.1 - 0.16 11.6 0.8 1.9 8.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat YgaB PF14182.1 EAU85741.1 - 2.4 8.4 6.4 0.48 10.6 0.2 2.8 3 0 0 3 3 3 0 YgaB-like protein GST_N_3 PF13417.1 EAU85742.1 - 2.1e-10 40.6 0.2 7.4e-10 38.9 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU85742.1 - 3.6e-08 33.2 0.0 7.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU85742.1 - 5.8e-05 22.9 0.1 0.00013 21.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU85742.1 - 0.00069 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAU85742.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EAU85742.1 - 0.1 13.0 0.1 0.45 11.0 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NMO PF03060.10 EAU85743.2 - 3.1e-64 217.2 0.1 4.2e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAU85743.2 - 9.3e-09 34.6 0.0 0.0001 21.3 0.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.12 EAU85743.2 - 0.024 13.7 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 EAU85743.2 - 0.032 13.5 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TOH_N PF12549.3 EAU85743.2 - 0.19 11.3 1.3 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal TPR_12 PF13424.1 EAU85746.1 - 1.7e-11 43.8 6.9 5.3e-05 23.0 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU85746.1 - 0.00089 19.0 15.4 0.23 11.4 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 EAU85746.1 - 0.001 17.9 0.0 0.0033 16.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 EAU85746.1 - 0.0033 17.5 0.0 0.073 13.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EAU85746.1 - 0.019 14.4 0.2 7.2 5.9 0.1 2.6 1 1 1 2 2 2 0 AAA domain TPR_11 PF13414.1 EAU85746.1 - 0.019 14.5 3.7 0.2 11.3 0.1 3.5 3 0 0 3 3 3 0 TPR repeat Baculo_PEP_C PF04513.7 EAU85746.1 - 0.02 14.7 0.8 0.065 13.0 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_10 PF13374.1 EAU85746.1 - 0.028 14.3 1.1 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 EAU85746.1 - 0.037 14.3 0.1 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin TPR_19 PF14559.1 EAU85746.1 - 0.057 13.7 2.3 2.2 8.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAU85746.1 - 0.07 13.8 10.5 0.35 11.6 0.0 5.6 6 1 0 6 6 5 0 Tetratricopeptide repeat AAA_16 PF13191.1 EAU85746.1 - 0.28 11.1 3.4 0.66 9.9 0.1 3.2 3 1 0 3 3 3 0 AAA ATPase domain Cyt-b5 PF00173.23 EAU85747.2 - 2.2e-12 46.5 0.1 2.7e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 EAU85748.1 - 3e-13 49.3 0.0 3.6e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AhpC-TSA PF00578.16 EAU85749.1 - 3.8e-26 91.2 0.0 4.6e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EAU85749.1 - 3.4e-15 55.8 0.0 4.3e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Ribosomal_S19e PF01090.14 EAU85750.1 - 3.3e-57 191.8 0.1 3.8e-57 191.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Androgen_recep PF02166.11 EAU85750.1 - 0.059 12.2 0.0 0.16 10.7 0.0 1.5 1 1 1 2 2 2 0 Androgen receptor F-box-like PF12937.2 EAU85751.1 - 6.7e-11 41.7 1.1 1.2e-10 40.9 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU85751.1 - 0.003 17.1 1.5 0.025 14.2 1.0 2.6 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU85752.2 - 5.6e-08 32.3 0.1 1.6e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85752.2 - 0.033 13.8 0.0 0.094 12.4 0.0 1.7 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 EAU85752.2 - 0.11 12.1 1.1 20 4.9 0.0 4.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU85752.2 - 0.38 10.5 3.2 2.4 7.9 0.2 3.5 4 0 0 4 4 4 0 Leucine rich repeat VWA_2 PF13519.1 EAU85754.2 - 2.3e-12 47.3 0.0 3.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Zw10 PF06248.8 EAU85754.2 - 0.13 10.3 0.4 0.18 9.9 0.2 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Miro PF08477.8 EAU85755.2 - 7.8e-36 123.1 0.0 1.2e-19 70.9 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EAU85755.2 - 3.4e-33 113.2 0.0 6.9e-33 112.2 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EAU85755.2 - 2e-31 107.0 0.1 5.3e-31 105.7 0.1 1.8 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EAU85755.2 - 9.9e-31 106.3 0.0 1.7e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Ras family EF-hand_6 PF13405.1 EAU85755.2 - 1.7e-10 39.9 0.5 0.00046 19.8 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EAU85755.2 - 2.8e-10 38.7 2.2 0.00041 19.4 0.0 2.8 2 0 0 2 2 2 2 EF hand Arf PF00025.16 EAU85755.2 - 1e-09 37.8 0.0 0.00034 19.8 0.0 2.9 2 2 0 2 2 2 2 ADP-ribosylation factor family EF-hand_7 PF13499.1 EAU85755.2 - 2.9e-09 36.9 0.8 0.0029 17.7 0.0 2.9 3 1 0 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EAU85755.2 - 6.1e-09 34.8 4.6 0.00033 19.8 0.1 2.7 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.18 EAU85755.2 - 5.7e-08 32.7 0.0 0.00096 19.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EAU85755.2 - 4.8e-07 29.9 0.0 0.062 13.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EAU85755.2 - 3.6e-06 26.7 0.1 0.041 13.5 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EAU85755.2 - 6.1e-06 26.3 0.7 0.11 12.4 0.1 2.7 3 0 0 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.18 EAU85755.2 - 1.2e-05 25.2 0.8 0.043 13.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 EAU85755.2 - 3.9e-05 23.9 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EAU85755.2 - 4.4e-05 22.9 0.1 0.043 13.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EAU85755.2 - 4.9e-05 23.3 0.0 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EAU85755.2 - 0.00011 22.5 0.0 0.39 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EAU85755.2 - 0.00019 21.6 0.1 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU85755.2 - 0.00022 22.0 0.0 0.24 12.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EAU85755.2 - 0.00024 20.8 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EAU85755.2 - 0.00033 20.5 0.1 0.55 10.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EAU85755.2 - 0.00033 20.3 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAU85755.2 - 0.00036 19.7 0.0 0.071 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EAU85755.2 - 0.00052 19.6 1.8 4.8 6.6 0.1 4.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein EF-hand_8 PF13833.1 EAU85755.2 - 0.00076 19.0 1.2 0.4 10.3 0.2 2.9 2 0 0 2 2 2 1 EF-hand domain pair PduV-EutP PF10662.4 EAU85755.2 - 0.0008 18.9 0.0 0.2 11.1 0.0 2.7 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EAU85755.2 - 0.0011 18.0 0.0 0.032 13.2 0.0 2.3 2 0 0 2 2 2 1 Septin EF-hand_10 PF14788.1 EAU85755.2 - 0.0017 18.0 1.0 0.012 15.3 0.1 2.3 2 0 0 2 2 2 1 EF hand RNA_helicase PF00910.17 EAU85755.2 - 0.0018 18.4 0.0 0.81 9.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.13 EAU85755.2 - 0.0027 17.2 0.0 0.64 9.5 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EAU85755.2 - 0.0032 16.9 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EAU85755.2 - 0.0051 16.3 0.1 2.3 7.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EAU85755.2 - 0.0052 16.5 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase DUF815 PF05673.8 EAU85755.2 - 0.0061 15.5 0.1 0.48 9.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 EAU85755.2 - 0.0066 15.9 0.1 0.92 8.9 0.0 3.4 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EAU85755.2 - 0.0066 15.6 0.0 2.1 7.5 0.0 2.5 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EAU85755.2 - 0.0092 15.8 0.0 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EAU85755.2 - 0.011 14.4 0.0 2 7.0 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AAA_23 PF13476.1 EAU85755.2 - 0.014 15.7 0.4 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EAU85755.2 - 0.015 14.7 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EAU85755.2 - 0.019 13.8 0.0 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AIG1 PF04548.11 EAU85755.2 - 0.023 13.8 0.0 0.07 12.2 0.0 1.8 2 0 0 2 2 2 0 AIG1 family VirE PF05272.6 EAU85755.2 - 0.03 13.8 0.0 2.1 7.7 0.0 3.1 3 1 0 3 3 3 0 Virulence-associated protein E cobW PF02492.14 EAU85755.2 - 0.031 13.7 0.1 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EAU85755.2 - 0.036 13.1 0.0 6.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 EAU85755.2 - 0.052 13.2 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) EF-hand_9 PF14658.1 EAU85755.2 - 0.067 13.1 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain MCM PF00493.18 EAU85755.2 - 0.067 11.9 0.1 0.19 10.4 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family Guanylate_kin PF00625.16 EAU85755.2 - 0.07 12.5 0.1 0.24 10.8 0.0 1.8 2 0 0 2 2 1 0 Guanylate kinase TrwB_AAD_bind PF10412.4 EAU85755.2 - 0.078 11.5 0.1 4.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SPARC_Ca_bdg PF10591.4 EAU85755.2 - 0.092 12.7 2.1 0.68 9.9 0.0 2.8 3 1 1 4 4 2 0 Secreted protein acidic and rich in cysteine Ca binding region AAA_10 PF12846.2 EAU85755.2 - 0.12 11.7 0.0 7 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain F-box-like PF12937.2 EAU85756.2 - 3.4e-06 26.6 0.4 7.3e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU85756.2 - 1.3e-05 24.6 0.3 2.6e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EAU85756.2 - 0.028 14.2 1.2 0.59 10.1 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat RasGEF PF00617.14 EAU85757.2 - 7.7e-50 169.2 0.0 1.2e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EAU85757.2 - 8.9e-21 73.9 0.0 2.6e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EAU85757.2 - 2e-13 49.6 0.0 3.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU85757.2 - 2.3e-12 46.2 0.0 5.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAU85757.2 - 1.7e-11 43.3 0.0 3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain GRASP55_65 PF04495.9 EAU85758.2 - 0.00017 21.6 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EAU85758.2 - 0.011 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Thi4 PF01946.12 EAU85759.2 - 1.2e-93 312.4 0.1 1.5e-93 312.1 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EAU85759.2 - 2.4e-10 39.8 0.6 8.6e-09 34.7 0.4 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU85759.2 - 1e-07 31.2 0.9 5.8e-07 28.7 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAU85759.2 - 1.1e-06 28.5 0.2 3e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU85759.2 - 2.4e-06 26.6 3.2 2.6e-05 23.2 0.4 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EAU85759.2 - 4.1e-06 26.8 0.6 6.6e-06 26.1 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAU85759.2 - 7.2e-06 25.3 0.4 9.5e-06 24.9 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAU85759.2 - 8.7e-06 25.5 2.0 9e-05 22.2 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAU85759.2 - 0.0008 19.5 0.7 0.0025 17.8 0.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU85759.2 - 0.0017 16.8 0.9 0.0032 15.9 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EAU85759.2 - 0.014 14.3 0.2 0.12 11.2 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EAU85759.2 - 0.038 12.6 0.4 0.058 12.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.14 EAU85759.2 - 0.073 12.2 0.1 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 EAU85759.2 - 0.081 11.9 0.1 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain CM_2 PF01817.16 EAU85760.1 - 1.1e-10 41.4 0.2 8.8e-08 32.1 0.0 3.2 3 1 0 3 3 3 2 Chorismate mutase type II Septin PF00735.13 EAU85761.2 - 4.7e-47 160.3 0.1 9.7e-18 64.1 0.0 3.2 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 EAU85761.2 - 9e-05 22.4 0.0 0.00023 21.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU85761.2 - 0.00027 20.4 0.0 0.00064 19.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EAU85761.2 - 0.0058 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EAU85761.2 - 0.011 15.7 0.8 0.038 13.9 0.6 2.0 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 EAU85761.2 - 0.028 14.2 0.3 9.5 6.0 0.0 2.6 1 1 1 2 2 2 0 Dynamin family AAA PF00004.24 EAU85761.2 - 0.062 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EAU85761.2 - 0.062 13.5 0.6 0.33 11.2 0.4 2.2 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 EAU85761.2 - 0.068 12.8 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EAU85761.2 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EAU85761.2 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EAU85761.2 - 0.2 11.1 0.9 5.8 6.3 0.2 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EAU85762.2 - 6.4e-22 77.8 0.0 2.4e-08 33.3 0.0 3.9 3 1 1 4 4 4 3 Septin Zn_clus PF00172.13 EAU85762.2 - 4.5e-19 68.0 27.2 8.7e-10 38.3 7.3 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EAU85763.1 - 2.5e-11 43.2 7.7 3.8e-11 42.7 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.16 EAU85764.1 - 4.1e-200 665.6 0.2 4.7e-200 665.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family LRR_8 PF13855.1 EAU85765.1 - 0.13 12.0 0.0 1.9 8.3 0.0 3.0 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EAU85766.2 - 0.023 14.4 0.4 0.061 13.0 0.3 1.8 1 0 0 1 1 1 0 F-box-like RIO1 PF01163.17 EAU85767.2 - 1.3e-68 230.0 0.0 2.3e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EAU85767.2 - 5e-06 26.4 0.1 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EAU85767.2 - 0.00048 19.2 1.8 0.41 9.6 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EAU85767.2 - 0.0023 17.1 0.0 0.0053 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Myc_N PF01056.13 EAU85767.2 - 2.2 7.3 17.8 0.99 8.5 6.9 2.2 2 0 0 2 2 2 0 Myc amino-terminal region GFA PF04828.9 EAU85769.2 - 3.3e-09 36.5 13.0 3e-07 30.2 1.7 3.3 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF3767 PF12597.3 EAU85770.2 - 1e-21 76.7 0.0 1.2e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Rhodanese PF00581.15 EAU85771.2 - 1.5e-05 25.2 0.0 2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Tetraspannin PF00335.15 EAU85773.1 - 2.2e-12 46.7 15.2 3e-12 46.2 10.5 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1673 PF07895.6 EAU85773.1 - 0.017 14.6 0.3 0.017 14.6 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) F-box-like PF12937.2 EAU85775.1 - 4.1e-06 26.4 0.4 4.1e-06 26.4 0.3 2.6 2 1 0 2 2 2 1 F-box-like Cytochrome_CBB3 PF13442.1 EAU85775.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III GSH_synth_ATP PF03917.12 EAU85776.2 - 3.5e-92 308.8 0.0 7.1e-92 307.8 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EAU85776.2 - 9.3e-34 115.6 0.0 1.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase F-box-like PF12937.2 EAU85777.2 - 2.5e-09 36.7 4.1 5.7e-08 32.3 1.5 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EAU85777.2 - 0.62 9.7 10.9 13 5.5 0.7 3.7 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.1 EAU85778.2 - 0.03 14.0 0.2 1 9.1 0.1 3.3 2 1 1 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EAU85778.2 - 2.3 7.9 9.5 6.7 6.4 0.5 4.8 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EAU85779.1 - 0.00039 20.0 0.0 0.0013 18.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU85779.1 - 0.18 11.4 0.5 7.5 6.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_hydro_15 PF00723.16 EAU85780.2 - 8.8e-94 314.5 0.0 1.1e-93 314.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EAU85780.2 - 2.6e-28 97.4 0.1 4.7e-28 96.6 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain Homeobox PF00046.24 EAU85781.1 - 2.9e-11 42.8 0.1 6.3e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAU85781.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.3 2 0 0 2 2 2 0 Homeobox KN domain adh_short PF00106.20 EAU85783.2 - 1.2e-18 67.5 0.2 1.4e-18 67.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU85783.2 - 5.2e-10 39.2 0.4 6.3e-10 39.0 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAU85783.2 - 2.4e-06 27.6 0.3 3.4e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EAU85783.2 - 9.9e-06 25.4 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EAU85783.2 - 0.00021 20.3 0.1 0.00024 20.1 0.1 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EAU85783.2 - 0.00041 19.6 0.5 0.00055 19.2 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EAU85783.2 - 0.0014 18.1 0.1 0.0028 17.1 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EAU85783.2 - 0.0022 18.0 0.7 0.0031 17.6 0.5 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EAU85783.2 - 0.0039 16.1 0.7 0.0063 15.4 0.5 1.4 1 1 0 1 1 1 1 Male sterility protein 2-Hacid_dh_C PF02826.14 EAU85783.2 - 0.0093 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EAU85783.2 - 0.087 11.8 0.1 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TAF PF02969.12 EAU85784.2 - 1e-19 70.2 0.2 1.9e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EAU85784.2 - 9.9e-18 64.0 0.1 2.6e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Urb2 PF10441.4 EAU85784.2 - 0.018 14.6 1.0 0.025 14.2 0.0 1.7 2 0 0 2 2 2 0 Urb2/Npa2 family Histone PF00125.19 EAU85784.2 - 0.019 15.0 0.2 0.047 13.8 0.1 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RIX1 PF08167.7 EAU85784.2 - 0.033 13.8 2.5 0.06 13.0 1.7 1.5 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Ufd2P_core PF10408.4 EAU85784.2 - 0.12 10.5 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core CENP-S PF15630.1 EAU85784.2 - 0.15 12.2 0.1 0.41 10.8 0.1 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S HEAT_EZ PF13513.1 EAU85784.2 - 0.22 12.0 10.3 0.37 11.3 0.0 4.7 3 2 2 5 5 5 0 HEAT-like repeat HemY_N PF07219.8 EAU85785.2 - 0.067 12.7 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Gal-bind_lectin PF00337.17 EAU85786.2 - 4.3e-14 51.9 0.0 5.1e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Gal-bind_lectin PF00337.17 EAU85788.2 - 5.6e-13 48.3 0.0 6.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Aldo_ket_red PF00248.16 EAU85789.2 - 3.9e-63 212.9 0.0 4.6e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1688 PF07958.6 EAU85789.2 - 0.088 11.3 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Ribosomal_L5_C PF00673.16 EAU85790.2 - 1.8e-14 53.2 0.0 3.9e-14 52.1 0.0 1.6 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Pkinase PF00069.20 EAU85791.2 - 1.8e-71 240.3 0.0 4.1e-71 239.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85791.2 - 6.7e-51 172.8 0.0 2e-50 171.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU85791.2 - 8.3e-06 24.9 0.0 4.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like E3_UbLigase_R4 PF13764.1 EAU85791.2 - 0.52 8.1 3.9 4.5 5.0 0.3 2.9 3 0 0 3 3 3 0 E3 ubiquitin-protein ligase UBR4 ECR1_N PF14382.1 EAU85795.2 - 0.18 11.1 1.2 0.23 10.7 0.1 1.7 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Syntaxin_2 PF14523.1 EAU85799.1 - 5.2e-23 81.0 9.0 1.7e-22 79.3 2.0 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EAU85799.1 - 1.3e-17 63.1 1.2 4e-17 61.6 0.8 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EAU85799.1 - 0.0013 18.8 0.6 0.0013 18.8 0.4 2.7 1 1 1 2 2 2 1 Syntaxin TMPIT PF07851.8 EAU85799.1 - 0.0063 15.6 1.2 0.18 10.8 0.0 2.1 1 1 2 3 3 3 1 TMPIT-like protein MCPsignal PF00015.16 EAU85799.1 - 0.11 12.0 6.4 0.034 13.7 0.9 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Bacillus_HBL PF05791.6 EAU85799.1 - 0.18 11.1 4.8 0.074 12.4 0.7 2.1 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TBPIP PF07106.8 EAU85799.1 - 9.7 5.7 10.0 12 5.4 1.2 2.7 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AMP-binding PF00501.23 EAU85801.1 - 1e-76 258.0 0.0 1.4e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU85801.1 - 3.7e-14 53.4 0.1 9e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EAU85802.2 - 2.1e-64 217.4 0.0 2.8e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU85802.2 - 8.7e-12 45.8 0.0 2.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FIST PF08495.5 EAU85804.1 - 2.2e-05 23.7 0.0 5.3e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 FIST N domain PG_binding_1 PF01471.13 EAU85806.2 - 0.15 12.0 0.2 9.4 6.3 0.1 2.6 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF1049 PF06305.6 EAU85807.2 - 0.2 11.1 0.5 0.37 10.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Carn_acyltransf PF00755.15 EAU85810.1 - 4.2e-161 536.9 0.0 5.4e-161 536.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Tyrosinase PF00264.15 EAU85812.2 - 3.8e-28 99.1 0.1 1.4e-27 97.3 0.0 1.9 1 1 0 1 1 1 1 Common central domain of tyrosinase UPF0172 PF03665.8 EAU85815.1 - 6.4e-41 140.0 0.0 9.6e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EAU85815.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase PF00069.20 EAU85816.2 - 0.0032 16.6 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PGA2 PF07543.7 EAU85816.2 - 0.023 14.4 2.2 0.063 13.0 0.4 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 Fungal_trans PF04082.13 EAU85818.2 - 2.1e-11 43.2 0.1 5e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAF1 PF04857.15 EAU85819.2 - 1.5e-65 221.1 0.0 2.1e-65 220.6 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DPBB_1 PF03330.13 EAU85822.1 - 2.9e-07 30.4 0.3 2.9e-06 27.1 0.0 2.4 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel F-box-like PF12937.2 EAU85824.1 - 4.7e-05 23.0 0.0 0.00019 21.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU85825.2 - 0.0011 18.6 0.2 0.0039 16.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like DPBB_1 PF03330.13 EAU85826.2 - 0.0026 17.6 0.2 0.033 14.1 0.1 2.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Desulfoferrod_N PF06397.7 EAU85826.2 - 0.0052 16.1 1.0 0.036 13.4 0.3 2.1 2 0 0 2 2 2 1 Desulfoferrodoxin, N-terminal domain zf-C2H2_4 PF13894.1 EAU85828.2 - 1.9e-09 37.1 21.4 0.04 14.2 0.7 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EAU85828.2 - 0.00017 21.5 19.6 0.016 15.3 0.9 4.3 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EAU85828.2 - 0.00029 21.0 20.6 0.029 14.6 1.3 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU85828.2 - 0.013 15.7 20.5 1 9.8 1.3 4.6 5 0 0 5 5 5 0 Zinc-finger double domain zinc_ribbon_5 PF13719.1 EAU85828.2 - 0.042 13.4 0.2 0.079 12.5 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EAU85828.2 - 0.052 13.2 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_7 PF15269.1 EAU85828.2 - 1.6 8.6 5.5 17 5.3 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger EBP PF05241.7 EAU85829.1 - 1.6e-56 190.4 6.9 1.9e-56 190.1 4.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.3 EAU85829.1 - 0.16 11.7 3.8 0.26 11.0 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) TPR_11 PF13414.1 EAU85830.2 - 1.4e-22 79.1 5.2 3.9e-17 61.6 0.3 2.3 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 EAU85830.2 - 2.1e-19 69.2 0.0 4.1e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 EAU85830.2 - 4.4e-14 51.3 3.2 6.3e-06 25.5 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU85830.2 - 1e-12 46.9 5.7 0.0017 18.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU85830.2 - 8.8e-09 35.8 8.1 1.7e-06 28.5 5.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU85830.2 - 3.9e-06 27.1 6.7 0.0095 16.2 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAU85830.2 - 2.3e-05 24.1 2.6 4.4e-05 23.2 1.8 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU85830.2 - 2.5e-05 24.4 6.8 0.028 15.0 0.2 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU85830.2 - 5e-05 23.1 0.4 0.13 12.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU85830.2 - 0.0076 15.9 0.8 0.36 10.7 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU85830.2 - 0.02 14.8 2.3 0.032 14.1 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAU85830.2 - 0.035 13.9 0.2 0.26 11.1 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CMAS PF02353.15 EAU85831.2 - 1.6e-48 165.1 0.0 1.1e-23 83.7 0.0 3.2 3 0 0 3 3 3 3 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EAU85831.2 - 5.3e-05 23.6 0.0 0.00091 19.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU85831.2 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU85831.2 - 0.0018 18.8 0.0 0.0042 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU85831.2 - 0.029 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 EAU85832.2 - 0.22 10.6 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF1902 PF08972.6 EAU85833.1 - 0.072 12.6 1.2 0.18 11.3 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) HEAT PF02985.17 EAU85833.1 - 0.13 12.4 0.1 0.64 10.2 0.1 2.3 1 0 0 1 1 1 0 HEAT repeat zf-TRAF PF02176.13 EAU85834.1 - 0.17 12.2 4.4 0.37 11.1 3.0 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger Transferase PF02458.10 EAU85835.1 - 4.4e-23 81.4 0.0 1.8e-22 79.3 0.0 1.7 2 0 0 2 2 2 1 Transferase family DUF4203 PF13886.1 EAU85836.1 - 0.0005 19.6 11.8 0.0008 18.9 8.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) AMP-binding PF00501.23 EAU85837.2 - 1.2e-72 244.5 0.1 4.4e-44 150.5 0.0 3.0 2 1 0 2 2 2 2 AMP-binding enzyme Fic_N PF13784.1 EAU85837.2 - 0.043 13.6 0.0 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Fic/DOC family N-terminal DUF4277 PF14104.1 EAU85837.2 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) ELFV_dehydrog PF00208.16 EAU85838.2 - 1.8e-50 171.8 0.0 2.8e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EAU85838.2 - 1.8e-22 78.7 0.0 4.2e-17 60.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EAU85838.2 - 0.033 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DIOX_N PF14226.1 EAU85839.2 - 5.6e-29 101.0 0.0 8.6e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAU85839.2 - 2.3e-23 82.3 0.0 3.8e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EAU85840.2 - 5.4e-16 58.9 0.8 5.2e-13 49.2 0.1 2.3 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAU85840.2 - 3e-07 30.2 0.3 7.9e-07 28.9 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EAU85840.2 - 7.7e-07 29.1 0.0 0.00062 19.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAU85840.2 - 0.0025 17.2 0.0 0.0077 15.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EAU85840.2 - 0.035 13.2 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.22 EAU85840.2 - 0.068 13.5 0.8 0.11 12.8 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU85841.1 - 2e-30 106.2 0.1 2.4e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU85841.1 - 5.9e-18 65.0 0.2 7.8e-15 55.0 0.0 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU85841.1 - 3e-07 30.7 0.1 0.0014 18.6 0.0 2.5 2 1 2 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU85841.1 - 1.6e-06 27.4 0.0 1.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EAU85841.1 - 1.6e-05 23.9 1.6 0.028 13.3 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU85841.1 - 0.00013 21.8 0.2 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EAU85841.1 - 0.00031 19.7 6.2 0.0053 15.6 0.1 4.0 4 1 1 5 5 5 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EAU85841.1 - 0.00034 19.5 1.4 0.0043 15.9 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 EAU85841.1 - 0.00034 20.7 0.1 0.65 10.0 0.0 2.6 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EAU85841.1 - 0.0004 20.5 0.1 0.075 13.2 0.0 3.0 2 2 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.1 EAU85841.1 - 0.00085 18.3 0.1 0.59 8.9 0.0 3.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EAU85841.1 - 0.0029 16.7 0.1 0.028 13.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EAU85841.1 - 0.003 16.6 0.0 0.061 12.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAU85841.1 - 0.0074 14.8 0.9 0.059 11.8 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 EAU85841.1 - 0.0075 14.9 0.1 0.042 12.4 0.0 2.1 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EAU85841.1 - 0.01 15.6 0.1 6.3 6.5 0.1 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 EAU85841.1 - 0.021 15.2 0.1 2.9 8.3 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EAU85841.1 - 0.047 13.4 0.6 0.92 9.2 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 EAU85841.1 - 0.073 12.4 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EAU85841.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 EAU85841.1 - 0.12 11.8 0.4 15 4.9 0.0 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA GPI-anchored PF10342.4 EAU85842.2 - 0.00029 21.2 0.0 0.0006 20.2 0.0 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PKD PF00801.15 EAU85842.2 - 0.11 12.2 0.1 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 PKD domain GPI-anchored PF10342.4 EAU85843.2 - 8.4e-10 38.9 0.2 1.4e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EAU85843.2 - 0.0036 16.7 0.0 0.0047 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) zf-C2H2_4 PF13894.1 EAU85844.2 - 8.7e-08 31.9 11.8 0.0038 17.4 0.3 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU85844.2 - 1.4e-06 28.2 12.3 0.014 15.6 0.1 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EAU85844.2 - 1.6e-05 24.8 6.8 0.033 14.4 0.2 3.3 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EAU85844.2 - 2.4e-05 24.4 12.0 0.039 14.2 0.1 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EAU85844.2 - 0.00042 20.3 6.7 0.0086 16.1 1.8 2.3 1 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 EAU85844.2 - 0.0081 16.0 0.4 5.4 6.9 0.1 2.8 1 1 1 2 2 2 2 IBR domain zf-Nse PF11789.3 EAU85844.2 - 0.13 11.8 0.4 8 6.0 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-C2HC PF01530.13 EAU85844.2 - 0.13 11.9 4.4 4.2 7.1 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2HC type F-box-like PF12937.2 EAU85845.1 - 0.00025 20.6 0.4 0.0011 18.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU85845.1 - 0.023 14.3 2.1 0.22 11.2 0.4 2.9 2 1 0 2 2 2 0 F-box domain NACHT PF05729.7 EAU85846.2 - 8.3e-09 35.3 0.0 2e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU85846.2 - 5.9e-06 26.3 0.0 3e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 EAU85846.2 - 7.1e-05 21.9 0.1 0.00096 18.2 0.0 2.1 1 1 0 2 2 2 1 KAP family P-loop domain AAA_5 PF07728.9 EAU85846.2 - 7.9e-05 22.4 0.0 0.001 18.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU85846.2 - 0.0056 16.8 0.0 0.017 15.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EAU85846.2 - 0.0063 16.6 0.0 0.039 14.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EAU85846.2 - 0.013 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EAU85846.2 - 0.1 12.7 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EAU85847.2 - 9.1e-10 38.1 0.0 1.8e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85847.2 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU85847.2 - 0.017 14.8 0.3 2 8.0 0.3 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.2 EAU85848.2 - 0.014 15.0 2.4 0.047 13.4 1.7 2.0 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 EAU85848.2 - 0.069 12.8 0.5 1.3 8.7 0.3 2.8 1 1 0 1 1 1 0 F-box domain Cep57_MT_bd PF06657.8 EAU85851.2 - 1.6e-20 72.8 0.0 1.6e-20 72.8 0.0 3.5 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EAU85851.2 - 6.9e-11 41.9 9.1 6.9e-11 41.9 6.3 3.4 4 0 0 4 4 4 1 Centrosome localisation domain of PPC89 Mnd1 PF03962.10 EAU85851.2 - 1.1 8.8 23.9 0.16 11.6 4.5 2.9 2 1 1 3 3 3 0 Mnd1 family TMCO5 PF14992.1 EAU85851.2 - 2.7 7.0 26.7 3.8 6.5 18.0 1.5 1 1 0 1 1 1 0 TMCO5 family CorA PF01544.13 EAU85851.2 - 8.2 5.3 8.1 13 4.6 5.0 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TMPIT PF07851.8 EAU85851.2 - 9.9 5.1 11.0 7.8 5.4 1.4 2.2 2 0 0 2 2 2 0 TMPIT-like protein BTB PF00651.26 EAU85853.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4492 PF14899.1 EAU85853.1 - 0.044 13.2 0.1 0.084 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Helitron_like_N PF14214.1 EAU85854.2 - 0.031 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Helitron helicase-like domain at N-terminus Tcp11 PF05794.8 EAU85859.2 - 3.4e-44 151.3 0.0 2.7e-43 148.3 0.0 2.4 1 1 0 1 1 1 1 T-complex protein 11 ATP-synt_ab PF00006.20 EAU85860.1 - 2.2e-61 207.1 0.0 3e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAU85860.1 - 4.4e-17 62.5 0.1 9.6e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EAU85860.1 - 8.8e-10 38.6 0.6 1.7e-09 37.7 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EAU85860.1 - 0.0099 15.7 0.2 0.022 14.6 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain TFCD_C PF12612.3 EAU85861.2 - 4.9e-40 137.0 0.0 2.2e-39 134.8 0.0 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EAU85861.2 - 0.015 15.3 5.3 0.34 11.1 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.2 EAU85861.2 - 0.043 14.2 0.0 0.76 10.1 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Isy1 PF06246.7 EAU85861.2 - 0.27 10.5 0.4 13 5.1 0.0 2.4 2 0 0 2 2 2 0 Isy1-like splicing family HEAT_EZ PF13513.1 EAU85861.2 - 0.43 11.1 3.6 21 5.7 0.0 4.9 3 0 0 3 3 3 0 HEAT-like repeat BUD22 PF09073.5 EAU85862.2 - 1.2e-61 209.1 25.2 1.5e-61 208.7 17.5 1.2 1 0 0 1 1 1 1 BUD22 PP1_inhibitor PF05361.7 EAU85862.2 - 0.0059 16.3 0.5 0.0059 16.3 0.3 1.8 2 0 0 2 2 2 1 PKC-activated protein phosphatase-1 inhibitor DUF2361 PF10153.4 EAU85862.2 - 0.33 11.1 5.1 6.1 7.0 3.5 2.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) PBP1_TM PF14812.1 EAU85862.2 - 1.9 8.8 18.6 1.5 9.1 1.2 3.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 EAU85862.2 - 5.3 4.8 19.1 11 3.7 13.3 1.5 1 0 0 1 1 1 0 Nop14-like family PP2C PF00481.16 EAU85866.2 - 9.2e-67 225.1 0.0 1.1e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EAU85866.2 - 0.0062 15.9 0.1 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C CS PF04969.11 EAU85867.2 - 1.2e-09 38.5 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 CS domain DUF727 PF05303.7 EAU85868.2 - 0.048 13.4 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF727) OGFr_N PF04664.8 EAU85869.1 - 7.3e-54 182.3 0.3 9.3e-54 181.9 0.2 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Mmp37 PF09139.6 EAU85871.2 - 6.2e-108 360.7 0.0 7.3e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 AAA_27 PF13514.1 EAU85872.2 - 0.0058 14.4 0.8 0.0073 14.0 0.6 1.0 1 0 0 1 1 1 1 AAA domain SR-25 PF10500.4 EAU85872.2 - 0.012 15.0 9.0 0.019 14.4 6.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATG16 PF08614.6 EAU85872.2 - 0.021 14.6 3.5 0.029 14.2 2.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ABC_tran_2 PF12848.2 EAU85872.2 - 0.1 12.4 2.0 0.19 11.5 1.4 1.4 1 0 0 1 1 1 0 ABC transporter POX PF07526.6 EAU85872.2 - 0.11 12.7 1.6 0.16 12.1 1.1 1.2 1 0 0 1 1 1 0 Associated with HOX DUF2413 PF10310.4 EAU85872.2 - 1.1 8.0 7.4 1.3 7.7 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) YTH PF04146.10 EAU85874.2 - 3.3e-51 172.5 0.0 6.6e-51 171.5 0.0 1.5 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EAU85874.2 - 1.2e-06 27.9 0.0 2.5e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU85874.2 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU85874.2 - 0.0023 17.8 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) nlz1 PF12402.3 EAU85874.2 - 0.048 13.9 2.8 0.15 12.4 1.9 1.8 1 0 0 1 1 1 0 NocA-like zinc-finger protein 1 WD40 PF00400.27 EAU85875.2 - 2.4e-28 96.9 1.0 9e-05 22.2 0.0 7.2 7 1 0 7 7 7 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EAU85875.2 - 0.00062 19.3 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 PQQ-like domain eIF2A PF08662.6 EAU85875.2 - 0.0025 17.5 0.3 3.2 7.4 0.0 3.2 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAU85875.2 - 0.0083 14.3 0.0 0.022 12.9 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EAU85875.2 - 0.07 11.4 0.0 0.13 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain RNase_H_2 PF13482.1 EAU85876.2 - 0.0029 17.4 0.1 0.91 9.3 0.0 2.2 2 0 0 2 2 2 2 RNase_H superfamily Pkinase PF00069.20 EAU85877.2 - 3.6e-44 150.8 0.0 5.9e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU85877.2 - 9.2e-21 74.0 0.0 3.3e-20 72.2 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU85877.2 - 2e-06 26.9 0.0 3.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU85877.2 - 3.5e-05 23.6 0.0 8.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Macoilin PF09726.4 EAU85877.2 - 0.014 13.6 12.6 0.033 12.4 8.7 1.5 1 0 0 1 1 1 0 Transmembrane protein Choline_kinase PF01633.15 EAU85877.2 - 0.076 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EAU85877.2 - 0.53 9.0 0.1 0.83 8.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HisG PF01634.13 EAU85878.2 - 1.1e-49 168.1 0.0 1.5e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EAU85878.2 - 2.9e-27 94.4 0.1 5.3e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EAU85878.2 - 0.00057 19.5 0.0 0.00079 19.0 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EAU85878.2 - 0.053 12.7 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Rot1 PF10681.4 EAU85880.1 - 5.3e-55 186.0 0.0 6.2e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Proteasome PF00227.21 EAU85881.2 - 1e-32 112.9 0.0 1.2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit ADH_N PF08240.7 EAU85885.1 - 8.2e-24 83.4 0.6 1.6e-23 82.5 0.2 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU85885.1 - 1.5e-08 34.2 0.0 3.1e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_9 PF13454.1 EAU85885.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding zf-met2 PF12907.2 EAU85886.2 - 0.08 12.9 0.1 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_4 PF13894.1 EAU85890.1 - 0.0011 19.0 1.6 0.21 11.9 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger PBP1_TM PF14812.1 EAU85890.1 - 0.033 14.4 6.8 0.033 14.4 4.7 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.21 EAU85890.1 - 0.041 14.2 0.1 0.041 14.2 0.1 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type DUF3419 PF11899.3 EAU85890.1 - 0.12 11.0 1.0 0.19 10.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3419) Sporozoite_P67 PF05642.6 EAU85890.1 - 0.19 9.5 3.0 0.24 9.2 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-met PF12874.2 EAU85890.1 - 0.21 11.8 0.5 6 7.2 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FHA PF00498.21 EAU85891.2 - 2e-18 66.2 0.0 3.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain Zn_clus PF00172.13 EAU85892.2 - 1.7e-08 34.2 10.5 3.3e-08 33.2 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAU85892.2 - 0.022 13.6 1.3 0.031 13.1 0.1 1.9 2 1 1 3 3 3 0 Fungal specific transcription factor domain zf-C3HC4_2 PF13923.1 EAU85893.1 - 2.4e-05 24.2 14.5 2.4e-05 24.2 10.1 3.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU85893.1 - 0.00021 21.0 13.7 0.00021 21.0 9.5 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EAU85893.1 - 0.00025 20.6 10.9 0.00025 20.6 7.6 3.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU85893.1 - 0.0014 18.2 9.7 0.0014 18.2 6.8 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EAU85893.1 - 0.012 15.4 9.2 0.012 15.4 6.4 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EAU85893.1 - 0.013 15.2 12.1 0.013 15.2 8.4 2.9 3 0 0 3 3 3 0 zinc-RING finger domain Kelch_6 PF13964.1 EAU85894.2 - 7.5e-27 92.3 3.2 2.5e-08 33.7 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EAU85894.2 - 4.5e-21 74.3 3.6 4.2e-08 32.8 0.0 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EAU85894.2 - 5.1e-17 61.5 2.5 2.9e-07 30.4 0.0 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EAU85894.2 - 9.3e-17 60.3 0.2 0.00023 20.6 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EAU85894.2 - 1.5e-16 59.9 0.5 0.00011 22.1 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EAU85894.2 - 2.2e-14 52.5 4.5 0.0018 17.9 0.0 5.1 4 1 0 4 4 4 3 Kelch motif BTB PF00651.26 EAU85894.2 - 0.1 12.6 0.2 15 5.6 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Pyridox_oxidase PF01243.15 EAU85895.2 - 4.1e-23 81.2 0.1 7.1e-23 80.4 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EAU85895.2 - 4.1e-06 27.0 0.1 8.1e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Rep_fac-A_3 PF08661.6 EAU85895.2 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Replication factor A protein 3 DUF3920 PF13058.1 EAU85898.2 - 0.0019 17.9 0.2 0.0031 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3920) DUF837 PF05769.6 EAU85898.2 - 0.004 16.6 11.2 0.14 11.6 3.4 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF837) Nsp1_C PF05064.8 EAU85898.2 - 0.012 15.2 5.2 0.032 13.8 0.5 2.8 2 1 1 3 3 3 0 Nsp1-like C-terminal region NYD-SP28_assoc PF14775.1 EAU85898.2 - 0.016 14.8 13.2 0.25 11.0 1.0 3.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain TPD52 PF04201.10 EAU85898.2 - 0.02 14.6 0.1 0.17 11.6 0.0 2.3 2 1 0 2 2 2 0 Tumour protein D52 family DUF759 PF05537.6 EAU85898.2 - 0.049 12.3 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) IL15 PF02372.10 EAU85898.2 - 0.051 13.3 0.4 0.086 12.6 0.3 1.3 1 0 0 1 1 1 0 Interleukin 15 DUF2400 PF09674.5 EAU85898.2 - 0.23 11.1 1.6 0.44 10.2 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) Strep_SA_rep PF06696.6 EAU85898.2 - 0.39 10.5 4.2 9.2 6.1 0.2 2.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF3347 PF11827.3 EAU85898.2 - 0.48 10.4 6.8 0.26 11.2 2.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) HALZ PF02183.13 EAU85898.2 - 1.9 8.2 8.4 7 6.4 0.6 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper IFT20 PF14931.1 EAU85898.2 - 2.3 8.1 9.3 7.6 6.4 0.6 3.0 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 Baculo_PEP_C PF04513.7 EAU85898.2 - 4.5 7.1 8.1 5 6.9 4.6 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EAU85898.2 - 7.2 6.7 6.1 1.9 8.6 1.6 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 EAU85898.2 - 8.6 6.4 10.1 8.2 6.4 0.5 3.2 2 1 1 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.10 EAU85898.2 - 10 6.0 16.7 0.99 9.2 0.7 3.6 3 0 0 3 3 3 0 Basic region leucine zipper PH PF00169.24 EAU85899.2 - 0.027 14.6 0.1 0.15 12.3 0.1 2.3 1 1 0 1 1 1 0 PH domain OB_NTP_bind PF07717.11 EAU85900.2 - 1.4e-19 69.9 0.0 4.1e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAU85900.2 - 1.9e-19 69.5 1.3 2.8e-19 69.0 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAU85900.2 - 6.3e-14 51.5 0.1 1.1e-11 44.4 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EAU85900.2 - 6.3e-06 26.3 0.0 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EAU85900.2 - 6.5e-06 25.7 0.3 2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU85900.2 - 0.0052 16.6 0.1 0.14 11.9 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit KaiC PF06745.8 EAU85900.2 - 0.036 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EAU85900.2 - 0.049 13.9 5.8 0.13 12.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain SEN1_N PF12726.2 EAU85901.2 - 3.3e-186 620.5 0.1 4.4e-186 620.1 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EAU85901.2 - 7.3e-64 215.5 0.5 7.3e-64 215.5 0.4 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EAU85901.2 - 6.7e-60 201.8 0.0 1.4e-59 200.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU85901.2 - 3.4e-13 49.1 0.1 3.4e-12 45.9 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAU85901.2 - 6.1e-09 35.7 0.0 9.2e-05 22.1 0.0 2.7 1 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EAU85901.2 - 0.0001 21.9 0.2 0.068 12.6 0.0 3.8 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EAU85901.2 - 0.00012 21.5 0.1 0.00012 21.5 0.1 3.0 2 1 1 3 3 3 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EAU85901.2 - 0.0012 18.3 0.1 0.028 13.8 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU85901.2 - 0.0013 18.8 0.1 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU85901.2 - 0.0017 18.3 0.0 0.0089 16.0 0.0 2.4 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 EAU85901.2 - 0.0028 17.5 0.0 0.015 15.1 0.0 2.2 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EAU85901.2 - 0.0038 16.8 0.1 0.58 9.7 0.0 3.1 2 1 0 2 2 2 1 Helicase AAA_25 PF13481.1 EAU85901.2 - 0.0064 15.9 0.0 0.02 14.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAU85901.2 - 0.0074 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EAU85901.2 - 0.01 14.8 0.8 1.8 7.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EAU85901.2 - 0.029 13.2 0.0 0.074 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 EAU85901.2 - 0.053 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 EAU85901.2 - 0.2 12.4 1.4 0.68 10.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain Translin PF01997.11 EAU85902.1 - 2.1e-44 151.5 0.0 2.4e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Translin family CBFD_NFYB_HMF PF00808.18 EAU85903.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FancD2 PF14631.1 EAU85903.1 - 1.3 6.0 3.7 1.7 5.6 2.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DIOX_N PF14226.1 EAU85906.2 - 1.3e-23 83.7 0.1 2e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAU85906.2 - 0.023 14.9 0.1 0.48 10.7 0.0 2.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyoxalase_3 PF13468.1 EAU85906.2 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase-like domain tRNA_bind PF01588.15 EAU85907.1 - 1.8e-29 101.3 0.0 3.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EAU85907.1 - 1.5e-05 25.3 0.3 4.2e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU85907.1 - 0.00058 19.7 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU85907.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NPR3 PF03666.8 EAU85907.1 - 0.49 8.8 2.7 0.74 8.2 1.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.3 EAU85907.1 - 2.9 6.5 8.7 4.1 6.0 6.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_L6 PF00347.18 EAU85908.2 - 1e-24 86.7 0.0 1.9e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 PLDc PF00614.17 EAU85909.2 - 4.1e-14 51.8 0.5 7.3e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EAU85909.2 - 8.5e-12 44.9 0.0 3.9e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EAU85909.2 - 2.3e-08 33.8 0.0 6.4e-07 29.1 0.0 2.7 2 0 0 2 2 2 1 PX domain ThiF PF00899.16 EAU85910.2 - 5.9e-18 65.0 0.0 1.6e-17 63.6 0.0 1.6 2 0 0 2 2 2 1 ThiF family Fungal_trans PF04082.13 EAU85911.2 - 1.7e-23 82.7 0.1 2.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PPR_2 PF13041.1 EAU85912.1 - 1.4e-06 28.1 0.1 0.0062 16.4 0.0 3.5 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 EAU85912.1 - 0.032 14.2 0.3 56 4.0 0.0 4.3 4 0 0 4 4 4 0 PPR repeat GRASP55_65 PF04495.9 EAU85913.2 - 2.2e-52 176.7 0.0 2.3e-42 144.2 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EAU85913.2 - 0.0021 17.9 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 2 PDZ domain RhgB_N PF09284.5 EAU85914.2 - 1.4e-35 122.8 3.6 2.6e-17 63.0 0.8 2.3 1 1 1 2 2 2 2 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EAU85914.2 - 9.6e-18 64.3 0.2 2.2e-09 37.2 0.1 2.6 1 1 1 2 2 2 2 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EAU85914.2 - 1.7e-13 50.4 1.5 9.4e-13 48.1 0.1 2.4 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EAU85914.2 - 0.00086 19.3 1.0 0.0028 17.6 0.7 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain BTB PF00651.26 EAU85915.2 - 0.00077 19.4 0.0 1.2 9.1 0.0 3.2 3 0 0 3 3 3 3 BTB/POZ domain RRM_1 PF00076.17 EAU85916.2 - 2.3e-46 155.2 0.7 1.7e-17 62.8 0.0 5.3 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU85916.2 - 2.3e-38 129.9 0.8 1.8e-14 53.4 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU85916.2 - 4.6e-20 71.2 0.4 2.2e-08 33.7 0.0 5.2 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EAU85916.2 - 0.00017 21.4 5.5 0.00022 21.0 2.5 2.2 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) RRM_3 PF08777.6 EAU85916.2 - 0.00038 20.2 4.2 0.67 9.8 0.0 5.0 4 1 1 5 5 5 1 RNA binding motif Nup35_RRM_2 PF14605.1 EAU85916.2 - 0.012 15.3 0.0 6.5 6.6 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif NRDE-2 PF08424.5 EAU85916.2 - 0.049 12.4 7.5 2.5 6.9 3.5 3.2 3 1 0 3 3 3 0 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.6 EAU85916.2 - 0.077 12.7 0.6 0.24 11.1 0.2 2.0 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Cytochrom_B562 PF07361.6 EAU85916.2 - 0.33 11.3 4.3 0.59 10.5 0.0 3.3 3 1 1 4 4 4 0 Cytochrome b562 TPR_16 PF13432.1 EAU85916.2 - 0.34 11.6 8.4 0.37 11.5 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.2 EAU85917.2 - 5e-11 42.1 0.3 5e-11 42.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like adh_short PF00106.20 EAU85918.1 - 3e-20 72.7 1.1 2.2e-13 50.4 0.1 2.5 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 EAU85918.1 - 4.4e-18 65.9 0.1 1.3e-16 61.0 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU85918.1 - 1.4e-06 28.1 0.2 3.3e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 KR domain SKN1 PF03935.10 EAU85919.2 - 1.7e-195 649.9 0.1 2.2e-195 649.6 0.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Neurensin PF14927.1 EAU85919.2 - 0.063 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Neurensin Pex14_N PF04695.8 EAU85919.2 - 4.9 7.2 0.0 4.9 7.2 0.0 2.8 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RasGEF PF00617.14 EAU85921.2 - 2.9e-60 203.2 0.2 5.4e-60 202.3 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EAU85921.2 - 1.1e-20 73.6 0.2 2.8e-20 72.3 0.1 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EAU85921.2 - 1.3e-15 56.5 0.1 3e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU85921.2 - 1e-13 50.5 0.1 2.3e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU85921.2 - 8.8e-13 47.5 0.0 1.6e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EAU85921.2 - 1e-06 28.5 12.5 8.6e-05 22.3 5.3 2.7 2 0 0 2 2 2 2 WW domain ACCA PF03255.9 EAU85921.2 - 0.61 9.6 2.3 23 4.5 0.0 3.2 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit AATF-Che1 PF13339.1 EAU85921.2 - 4.3 7.4 9.5 2.5 8.2 0.0 4.1 4 1 0 5 5 5 0 Apoptosis antagonizing transcription factor SR-25 PF10500.4 EAU85922.2 - 0.00079 18.9 53.9 0.00079 18.9 37.4 2.5 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein DUF2413 PF10310.4 EAU85922.2 - 0.81 8.4 13.8 1.6 7.5 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CBFD_NFYB_HMF PF00808.18 EAU85923.2 - 5.9e-17 61.4 0.3 1.1e-16 60.6 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAU85923.2 - 0.00034 20.6 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF605 PF04652.11 EAU85923.2 - 0.0012 18.3 6.1 0.0014 18.0 4.3 1.2 1 0 0 1 1 1 1 Vta1 like Bromo_TP PF07524.8 EAU85923.2 - 0.025 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated YL1 PF05764.8 EAU85923.2 - 0.43 10.1 8.8 0.64 9.5 6.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Methyltransf_33 PF10017.4 EAU85926.1 - 1e-34 119.1 0.7 1.7e-34 118.4 0.5 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EAU85926.1 - 5.9e-26 91.3 1.3 1.6e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EAU85926.1 - 1.3e-08 35.2 0.8 2.7e-08 34.2 0.6 1.5 1 0 0 1 1 1 1 DinB superfamily Matrilin_ccoil PF10393.4 EAU85926.1 - 0.29 10.5 0.0 0.57 9.6 0.0 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Choline_kinase PF01633.15 EAU85927.2 - 0.0036 16.9 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EAU85927.2 - 0.0047 16.0 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU85927.2 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EAU85927.2 - 0.061 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF2883 PF11097.3 EAU85927.2 - 0.11 12.6 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2883) SET PF00856.23 EAU85929.2 - 2.8e-06 27.7 0.0 9.3e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 SET domain NIPSNAP PF07978.8 EAU85929.2 - 0.085 12.8 0.2 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 NIPSNAP DUF202 PF02656.10 EAU85930.2 - 8.6e-18 64.3 0.1 8.6e-18 64.3 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF202) F-box-like PF12937.2 EAU85932.2 - 5e-07 29.3 0.5 5e-07 29.3 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU85932.2 - 0.45 10.2 6.6 0.31 10.7 1.6 2.6 2 1 0 2 2 2 0 F-box domain UAA PF08449.6 EAU85933.2 - 2.9e-57 193.9 6.8 3.5e-57 193.6 4.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EAU85933.2 - 1.1e-07 31.6 11.5 9.6e-07 28.5 3.0 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EAU85933.2 - 1.1e-07 31.9 10.4 4.2e-05 23.5 1.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF914 PF06027.7 EAU85933.2 - 0.0017 17.2 0.7 0.0017 17.2 0.5 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) DUF2427 PF10348.4 EAU85933.2 - 0.16 11.5 2.7 0.95 9.0 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Methyltransf_23 PF13489.1 EAU85934.2 - 1.2e-10 41.3 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU85934.2 - 1.3e-09 37.8 0.0 2.1e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU85934.2 - 1.3e-08 35.2 0.0 4.5e-07 30.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU85934.2 - 3.7e-08 33.9 0.1 4.2e-05 24.0 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU85934.2 - 7.9e-07 29.4 0.1 8.8e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EAU85934.2 - 5.3e-06 25.3 0.0 5.5e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EAU85934.2 - 9.8e-06 25.0 0.0 0.0027 17.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EAU85934.2 - 0.0012 18.4 0.0 0.0043 16.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EAU85934.2 - 0.0014 18.9 0.6 0.9 9.9 0.1 3.0 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU85934.2 - 0.0094 15.0 0.0 0.11 11.6 0.0 2.3 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EAU85934.2 - 0.021 13.9 0.0 0.057 12.4 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.5 EAU85934.2 - 0.048 13.1 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EAU85934.2 - 0.12 12.3 0.3 16 5.5 0.0 2.8 1 1 1 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EAU85934.2 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase N6_Mtase PF02384.11 EAU85934.2 - 0.18 10.8 0.0 0.37 9.8 0.0 1.5 2 0 0 2 2 2 0 N-6 DNA Methylase RRM_1 PF00076.17 EAU85935.2 - 4.6e-08 32.5 0.0 8.8e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU85935.2 - 7.7e-07 28.9 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU85935.2 - 0.00018 21.3 0.4 0.00049 19.9 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EAU85935.2 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif K_channel_TID PF07941.6 EAU85936.2 - 0.1 12.8 0.2 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain LRR_4 PF12799.2 EAU85938.2 - 1.5e-15 56.3 27.5 0.00011 21.6 0.3 5.7 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU85938.2 - 6.4e-11 41.8 23.4 7.5e-05 22.4 2.4 5.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.1 EAU85938.2 - 4.7e-07 29.5 7.1 0.00039 20.0 1.4 3.2 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 EAU85938.2 - 0.07 13.1 21.0 0.65 10.2 0.2 7.4 6 1 1 7 7 7 0 Leucine Rich Repeat ABC2_membrane_3 PF12698.2 EAU85938.2 - 1.3 8.0 1.2 2.3 7.1 0.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein LRR_7 PF13504.1 EAU85938.2 - 1.4 9.4 25.1 2.5 8.6 0.2 7.6 8 1 0 8 8 8 0 Leucine rich repeat LRR_6 PF13516.1 EAU85938.2 - 6.9 7.0 21.8 1.3 9.2 0.0 6.5 5 2 1 6 6 6 0 Leucine Rich repeat Homeobox_KN PF05920.6 EAU85939.2 - 1.8e-17 62.7 2.3 2.7e-17 62.1 0.1 2.5 2 0 0 2 2 2 1 Homeobox KN domain LRR_4 PF12799.2 EAU85939.2 - 1.4e-09 37.3 0.7 1.4e-07 30.9 0.1 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU85939.2 - 2.6e-07 30.2 0.6 6.9e-07 28.9 0.4 1.8 1 0 0 1 1 1 1 Leucine rich repeat Homeobox PF00046.24 EAU85939.2 - 4.4e-05 23.0 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain LRR_7 PF13504.1 EAU85939.2 - 0.0031 17.4 1.7 6.6 7.4 0.1 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EAU85939.2 - 0.0039 17.0 3.2 2.1 8.6 0.2 3.7 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.1 EAU85939.2 - 0.025 14.1 0.2 5.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.1 EAU85939.2 - 0.13 12.3 2.0 1.2 9.4 0.1 3.1 2 1 1 3 3 3 0 Leucine Rich repeat cobW PF02492.14 EAU85940.2 - 5.3e-28 97.6 0.0 6.4e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EAU85940.2 - 0.0022 17.9 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TIP49 PF06068.8 EAU85940.2 - 0.0031 16.2 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EAU85940.2 - 0.0035 17.6 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU85940.2 - 0.008 16.9 0.1 0.018 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EAU85940.2 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 EAU85940.2 - 0.029 14.5 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EAU85940.2 - 0.036 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EAU85940.2 - 0.041 14.1 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EAU85940.2 - 0.061 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 EAU85940.2 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 EAU85940.2 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EAU85940.2 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain CbiA PF01656.18 EAU85940.2 - 0.11 11.8 0.2 0.2 11.0 0.2 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 EAU85940.2 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EAU85940.2 - 0.14 11.5 0.2 0.25 10.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF1762 PF08574.5 EAU85941.1 - 4.8e-10 39.7 11.8 4.8e-10 39.7 8.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1762) 3-alpha PF03475.9 EAU85941.1 - 0.14 11.8 0.7 3.7 7.3 0.5 2.5 2 0 0 2 2 2 0 3-alpha domain HCO3_cotransp PF00955.16 EAU85942.2 - 1.3e-55 189.0 7.7 1.2e-30 106.6 0.9 3.1 2 1 1 3 3 3 3 HCO3- transporter family Abhydrolase_5 PF12695.2 EAU85943.2 - 2.1e-18 66.5 1.8 7.7e-18 64.6 1.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU85943.2 - 4.1e-14 53.0 3.9 1.4e-13 51.3 2.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAU85943.2 - 2.7e-09 36.9 0.3 4.5e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EAU85943.2 - 1.3e-06 28.1 0.4 2.1e-05 24.2 0.1 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.7 EAU85943.2 - 0.00063 18.5 0.0 0.00094 18.0 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.13 EAU85943.2 - 0.017 14.5 0.0 0.044 13.1 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EAU85943.2 - 0.038 13.8 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S9 PF00326.16 EAU85943.2 - 0.056 12.6 0.2 0.22 10.6 0.1 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 EAU85943.2 - 0.14 10.7 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 HATPase_c PF02518.21 EAU85944.2 - 4.7e-21 74.5 0.3 8.4e-21 73.7 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PHY PF00360.15 EAU85944.2 - 5e-20 71.4 0.0 9.5e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.19 EAU85944.2 - 5.7e-19 68.1 0.1 2.2e-18 66.3 0.1 2.0 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EAU85944.2 - 3.7e-12 46.0 1.1 7.8e-12 45.0 0.8 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EAU85944.2 - 0.00096 19.5 0.0 0.0028 18.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold GAF PF01590.21 EAU85944.2 - 0.0094 16.0 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain CwfJ_C_1 PF04677.10 EAU85946.1 - 5.2e-32 110.0 0.1 8e-32 109.4 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EAU85946.1 - 2.4e-22 79.2 0.0 2.4e-22 79.2 0.0 3.5 4 0 0 4 4 4 1 Protein similar to CwfJ C-terminus 2 GTP_EFTU PF00009.22 EAU85947.2 - 1.3e-54 184.4 0.0 2.2e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAU85947.2 - 6e-15 54.8 0.0 1.6e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EAU85947.2 - 6.9e-09 35.4 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EAU85947.2 - 2.5e-08 33.8 0.0 7.5e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAU85947.2 - 7.6e-06 25.8 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 EAU85947.2 - 0.022 14.3 0.0 0.18 11.3 0.0 2.6 2 1 0 2 2 2 0 Elongation factor G, domain IV SRPRB PF09439.5 EAU85947.2 - 0.044 12.9 0.1 0.16 11.2 0.1 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EAU85947.2 - 0.11 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein CPSF_A PF03178.10 EAU85948.2 - 5.5e-40 137.4 0.0 5.4e-39 134.1 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EAU85948.2 - 8.1e-38 129.8 0.0 3.3e-37 127.8 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Na_Ca_ex PF01699.19 EAU85949.2 - 4.2e-23 81.5 32.5 9.1e-14 51.2 4.5 3.2 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EAU85949.2 - 8.4e-10 38.9 29.8 4.2e-09 36.6 8.9 3.7 2 0 0 2 2 2 2 Domain of unknown function (DUF307) Helicase_C_2 PF13307.1 EAU85951.2 - 7.7e-52 175.6 0.1 7.1e-50 169.2 0.0 2.9 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.10 EAU85951.2 - 1.3e-35 122.3 0.6 1.8e-27 95.8 0.0 3.4 1 1 1 2 2 2 2 DEAD_2 PhoH PF02562.11 EAU85951.2 - 0.00028 20.1 0.0 0.041 13.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EAU85951.2 - 0.0015 18.0 0.0 0.046 13.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU85951.2 - 0.0016 18.2 0.1 0.13 12.0 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU85951.2 - 0.011 15.9 0.1 3.6 7.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EAU85951.2 - 0.018 14.7 0.0 0.059 13.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 EAU85951.2 - 0.11 11.9 0.0 3.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 EAU85951.2 - 1.1 8.7 8.3 5.5 6.4 5.7 2.1 1 1 0 1 1 1 0 AAA domain adh_short PF00106.20 EAU85953.2 - 4.8e-30 104.6 0.0 6.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU85953.2 - 2.5e-13 50.3 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU85953.2 - 4e-07 29.8 0.0 9.7e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EAU85953.2 - 6.2e-05 22.5 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EAU85953.2 - 0.0085 15.8 2.7 0.019 14.7 1.7 1.7 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EAU85953.2 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EAU85953.2 - 0.044 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACR_tran PF00873.14 EAU85954.2 - 0.1 9.9 0.1 0.16 9.3 0.1 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family OB_NTP_bind PF07717.11 EAU85955.2 - 2.2e-29 101.5 0.1 7e-29 99.9 0.1 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAU85955.2 - 1.1e-26 92.7 0.0 1.1e-26 92.7 0.0 3.1 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAU85955.2 - 5.8e-14 51.7 0.0 1.5e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU85955.2 - 2.3e-07 30.4 0.3 1.3e-06 27.9 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU85955.2 - 0.00015 21.9 0.1 0.0013 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EAU85955.2 - 0.0013 17.7 0.0 0.0026 16.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EAU85955.2 - 0.0036 17.1 0.7 1.1 9.1 0.1 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EAU85955.2 - 0.11 12.2 1.0 0.26 11.0 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain HpcH_HpaI PF03328.9 EAU85956.2 - 1e-44 152.0 0.0 1.7e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EAU85956.2 - 3.9e-12 45.6 0.0 4.6e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold dsrm PF00035.20 EAU85958.1 - 2.3e-10 40.9 0.1 4.5e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EAU85958.1 - 3.1e-09 36.8 0.0 4.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EAU85958.1 - 0.0026 18.2 0.0 0.0054 17.1 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Glycos_transf_3 PF00591.16 EAU85959.2 - 9.1e-77 257.8 0.0 1.2e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EAU85959.2 - 1.7e-06 27.4 0.0 3.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain HEAT_2 PF13646.1 EAU85962.1 - 2.1e-46 156.1 9.9 2.4e-16 59.7 0.1 4.4 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.11 EAU85962.1 - 4e-25 85.7 0.6 0.0014 18.8 0.0 7.5 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EAU85962.1 - 7.6e-14 50.4 1.0 0.014 15.4 0.0 6.1 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EAU85962.1 - 7.2e-13 48.6 3.5 0.012 16.0 0.0 6.3 4 2 2 6 6 6 3 HEAT-like repeat Arm PF00514.18 EAU85962.1 - 1.9e-06 27.4 0.2 0.0092 15.7 0.0 3.8 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EAU85962.1 - 0.093 12.6 0.1 8 6.4 0.0 3.4 3 0 0 3 3 3 0 Importin-beta N-terminal domain Ribosomal_L10 PF00466.15 EAU85963.2 - 2.8e-14 52.8 0.0 3.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_S9 PF00326.16 EAU85964.1 - 2.3e-42 144.6 0.0 4.2e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAU85964.1 - 3.3e-07 30.4 0.0 1.1e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU85964.1 - 5.7e-07 29.3 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-CCHC_3 PF13917.1 EAU85966.2 - 1.1e-20 73.1 1.4 2.2e-20 72.1 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.4 EAU85966.2 - 0.0014 18.1 19.5 0.002 17.6 13.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TFIIF_alpha PF05793.7 EAU85966.2 - 0.015 13.7 10.8 0.017 13.5 7.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_viral_N PF00242.12 EAU85966.2 - 0.033 13.2 8.4 0.041 12.9 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RAP1 PF07218.6 EAU85966.2 - 0.073 11.1 5.7 0.087 10.9 4.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 EAU85966.2 - 0.21 9.8 5.7 0.22 9.7 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 EAU85966.2 - 0.29 9.1 5.7 0.34 8.8 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein AF-4 PF05110.8 EAU85966.2 - 0.72 7.6 23.6 0.97 7.2 16.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDK2AP PF09806.4 EAU85966.2 - 0.72 10.0 7.5 5.1 7.2 3.5 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF755 PF05501.6 EAU85966.2 - 0.73 9.9 20.9 1.5 8.9 14.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2146 PF10220.4 EAU85966.2 - 1.4 6.7 3.8 2.1 6.2 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) MRI PF15325.1 EAU85966.2 - 1.9 9.4 9.8 4.4 8.3 6.8 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection APC_CDC26 PF10471.4 EAU85966.2 - 2.1 9.1 9.5 4.5 8.0 6.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 MFMR PF07777.6 EAU85966.2 - 2.9 7.7 8.9 4 7.3 6.2 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR Nucleo_P87 PF07267.6 EAU85966.2 - 7.8 5.0 6.0 8.7 4.8 4.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Paf1 PF03985.8 EAU85966.2 - 10 4.7 12.9 13 4.3 8.9 1.1 1 0 0 1 1 1 0 Paf1 ATP-synt_C PF00137.16 EAU85967.2 - 2.5e-27 94.5 29.3 1.3e-16 60.2 5.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Zip PF02535.17 EAU85968.2 - 1.7e-33 115.9 5.6 2.6e-33 115.4 3.9 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter E1_dh PF00676.15 EAU85969.2 - 1.2e-82 277.0 0.0 1.5e-82 276.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component EphA2_TM PF14575.1 EAU85970.2 - 0.034 14.5 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SNF5 PF04855.7 EAU85972.2 - 1.4e-58 198.2 0.1 3.5e-58 196.9 0.0 1.6 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 F-box-like PF12937.2 EAU85973.1 - 5.6e-05 22.7 0.4 0.00085 19.0 0.0 3.0 4 0 0 4 4 4 1 F-box-like Waikav_capsid_1 PF12264.3 EAU85973.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Waikavirus capsid protein 1 LRR_4 PF12799.2 EAU85973.1 - 0.43 10.2 11.3 5.1 6.8 0.1 4.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) zf-C2H2 PF00096.21 EAU85975.1 - 5.3e-09 35.8 9.8 0.00018 21.6 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU85975.1 - 3.4e-08 33.3 15.1 6.1e-07 29.4 1.7 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU85975.1 - 7.1e-07 29.1 9.5 0.0043 17.2 1.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger WD40 PF00400.27 EAU85977.2 - 3.2e-12 45.8 2.5 0.19 11.6 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF2419 PF10343.4 EAU85978.1 - 4.3e-51 173.8 0.0 5.2e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Arrestin_N PF00339.24 EAU85980.2 - 0.077 12.8 0.1 0.55 10.0 0.0 2.1 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain TPR_MLP1_2 PF07926.7 EAU85981.2 - 8.5e-20 70.8 23.1 8.5e-20 70.8 16.0 16.6 6 5 7 14 14 14 7 TPR/MLP1/MLP2-like protein Ribosomal_S10 PF00338.17 EAU85982.1 - 6.5e-31 106.0 0.6 7.5e-31 105.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e AMP-binding PF00501.23 EAU85986.2 - 2.4e-82 276.5 0.1 3.6e-82 276.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Cytochrom_B561 PF03188.11 EAU85986.2 - 0.061 13.1 2.3 0.1 12.3 0.2 2.1 1 1 1 2 2 2 0 Eukaryotic cytochrome b561 Cation_ATPase_C PF00689.16 EAU85986.2 - 0.11 12.0 7.3 0.24 10.8 5.0 1.7 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus AAA_23 PF13476.1 EAU85987.1 - 4.5e-19 69.5 18.5 4.5e-19 69.5 12.8 8.3 1 1 2 3 3 3 1 AAA domain AAA_21 PF13304.1 EAU85987.1 - 5.5e-13 49.5 12.7 1.1e-07 32.1 0.4 4.5 3 1 1 4 4 4 2 AAA domain SbcCD_C PF13558.1 EAU85987.1 - 4.6e-11 42.4 0.1 1.5e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EAU85987.1 - 6.9e-10 38.5 0.1 6.9e-10 38.5 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EAU85987.1 - 2.4e-05 23.0 140.2 2.7e-05 22.8 0.0 7.8 2 1 5 9 9 9 5 AAA domain Reo_sigmaC PF04582.7 EAU85987.1 - 0.00061 19.0 13.2 0.0021 17.2 0.9 6.9 2 2 3 7 7 7 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 EAU85987.1 - 0.00078 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Lebercilin PF15619.1 EAU85987.1 - 0.00098 18.5 24.0 0.00098 18.5 16.6 10.1 3 3 8 11 11 11 3 Ciliary protein causing Leber congenital amaurosis disease ABC_tran PF00005.22 EAU85987.1 - 0.0021 18.3 0.0 0.0021 18.3 0.0 7.0 4 3 0 4 4 4 1 ABC transporter HrpB7 PF09486.5 EAU85987.1 - 0.0096 15.8 0.7 0.0096 15.8 0.5 9.4 3 2 5 8 8 8 2 Bacterial type III secretion protein (HrpB7) MRP-L47 PF06984.8 EAU85989.2 - 1.4e-12 47.3 0.1 4.2e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Draxin PF15550.1 EAU85989.2 - 0.0029 17.3 5.1 0.0039 16.8 3.6 1.2 1 0 0 1 1 1 1 Draxin MFS_1 PF07690.11 EAU85992.2 - 1.2e-28 99.9 35.6 4.5e-27 94.6 23.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3817 PF12823.2 EAU85992.2 - 0.027 14.8 1.3 0.027 14.8 0.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3817) Glyco_hydro_71 PF03659.9 EAU85993.2 - 1.7e-83 280.2 0.1 2.8e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 CRAL_TRIO PF00650.15 EAU85993.2 - 7.2e-26 90.5 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAU85993.2 - 9.9e-06 25.5 0.0 2.8e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain vATP-synt_AC39 PF01992.11 EAU85994.1 - 1.5e-102 343.1 0.1 1.7e-102 342.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DER1 PF04511.10 EAU85996.2 - 1.2e-46 158.7 3.1 1.6e-46 158.3 2.2 1.1 1 0 0 1 1 1 1 Der1-like family SAM_2 PF07647.12 EAU85997.2 - 9e-11 41.4 0.1 3.7e-10 39.5 0.0 2.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EAU85997.2 - 7.7e-06 25.9 0.0 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) His_Phos_2 PF00328.17 EAU85998.1 - 1.3e-39 136.5 0.0 1.6e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3752 PF12572.3 EAU85999.2 - 4.3e-41 140.5 8.3 4.3e-41 140.5 5.8 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) CRAL_TRIO PF00650.15 EAU86000.2 - 7.2e-24 84.0 0.0 1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAU86000.2 - 4.5e-06 26.7 0.0 8.7e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Motile_Sperm PF00635.21 EAU86001.2 - 1.2e-26 92.4 0.1 2.5e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 EAU86001.2 - 0.023 14.7 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase HALZ PF02183.13 EAU86001.2 - 0.094 12.4 0.7 0.19 11.4 0.5 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 EAU86001.2 - 0.56 9.7 4.3 1.3 8.5 2.9 1.5 1 0 0 1 1 1 0 Septum formation initiator PAT1 PF09770.4 EAU86001.2 - 2 6.5 27.6 2.7 6.1 19.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ABC_membrane PF00664.18 EAU86002.1 - 1.7e-91 306.4 27.7 1.6e-46 158.9 3.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAU86002.1 - 1.6e-70 235.7 0.1 4.4e-34 117.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAU86002.1 - 6.7e-15 54.9 3.2 3.9e-05 22.9 0.4 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU86002.1 - 8.7e-14 52.1 0.5 0.0003 20.8 0.0 4.7 4 1 0 4 4 3 3 AAA domain ABC_ATPase PF09818.4 EAU86002.1 - 1.4e-09 37.0 1.5 0.00022 19.9 0.0 2.9 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EAU86002.1 - 1.1e-08 34.4 1.9 0.0028 17.1 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU86002.1 - 5.2e-08 33.0 2.6 0.00039 20.4 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EAU86002.1 - 5.2e-08 33.7 0.0 0.014 16.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAU86002.1 - 4.1e-06 26.0 0.0 0.043 12.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAU86002.1 - 4.1e-05 23.7 2.0 0.16 12.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EAU86002.1 - 6.7e-05 23.2 1.4 0.095 13.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EAU86002.1 - 8.7e-05 22.1 0.7 1.3 8.5 0.2 3.7 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EAU86002.1 - 0.00023 21.5 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAU86002.1 - 0.00035 20.4 0.0 0.84 9.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EAU86002.1 - 0.00036 19.7 0.0 0.69 8.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.1 EAU86002.1 - 0.0011 18.8 2.8 1 9.3 0.2 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 EAU86002.1 - 0.0014 17.4 4.2 0.21 10.2 0.0 2.6 3 0 0 3 3 2 2 G-protein alpha subunit MobB PF03205.9 EAU86002.1 - 0.0022 17.6 0.2 1.8 8.2 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EAU86002.1 - 0.0024 17.5 0.1 3.2 7.3 0.0 2.7 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_5 PF07728.9 EAU86002.1 - 0.0027 17.4 0.1 4.3 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EAU86002.1 - 0.0031 17.0 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 EAU86002.1 - 0.0039 16.5 1.6 3.5 6.9 0.0 3.4 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.8 EAU86002.1 - 0.0048 15.8 0.0 0.73 8.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EAU86002.1 - 0.0081 16.1 0.1 2.4 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAU86002.1 - 0.0086 15.5 0.7 5.4 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA-like domain DUF87 PF01935.12 EAU86002.1 - 0.01 15.6 1.2 3.4 7.4 0.2 3.0 3 0 0 3 3 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EAU86002.1 - 0.011 15.6 0.0 5.5 6.9 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF3987 PF13148.1 EAU86002.1 - 0.019 13.5 0.0 0.24 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.13 EAU86002.1 - 0.021 14.3 0.0 1.4 8.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 EAU86002.1 - 0.035 13.1 0.0 4.4 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EAU86002.1 - 0.084 13.0 0.0 9.9 6.3 0.0 3.2 3 0 0 3 3 2 0 RNA helicase ATP-synt_ab PF00006.20 EAU86002.1 - 0.086 12.3 0.2 6.8 6.1 0.0 2.9 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 EAU86002.1 - 0.096 13.1 0.0 23 5.5 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EAU86002.1 - 0.11 12.0 0.1 6.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2628 PF10947.3 EAU86002.1 - 0.15 11.8 7.5 0.28 11.0 0.1 3.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2628) NB-ARC PF00931.17 EAU86002.1 - 0.18 10.6 0.0 16 4.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Pkinase PF00069.20 EAU86003.1 - 2e-72 243.4 0.0 2.6e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86003.1 - 3.5e-32 111.4 0.0 5e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EAU86003.1 - 9.5e-09 35.6 4.2 2.6e-08 34.2 2.9 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EAU86003.1 - 5.6e-05 22.2 0.0 0.00016 20.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EAU86003.1 - 0.0055 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU86003.1 - 0.032 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AFP PF02420.10 EAU86005.2 - 0.73 10.1 5.5 0.16 12.1 0.8 2.2 2 0 0 2 2 2 0 Insect antifreeze protein repeat BUD22 PF09073.5 EAU86007.1 - 0.058 12.4 2.3 0.1 11.6 1.6 1.4 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.20 EAU86010.2 - 5.9e-53 179.6 0.0 9.3e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86010.2 - 5e-25 88.0 0.3 2.1e-24 86.0 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU86010.2 - 1.4e-05 24.2 0.0 4e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EAU86010.2 - 0.00078 18.8 2.3 0.0012 18.2 0.1 2.2 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EAU86010.2 - 0.0047 16.0 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 EAU86011.2 - 1.5e-08 34.1 0.4 6.5e-06 25.7 0.2 2.6 2 0 0 2 2 2 2 F-box-like zf-CCCH PF00642.19 EAU86012.1 - 3.8e-11 42.3 20.4 8.5e-06 25.3 0.7 3.6 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Period_C PF12114.3 EAU86012.1 - 0.97 9.0 6.7 2 7.9 4.7 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Heme_oxygenase PF01126.15 EAU86014.1 - 1.8e-39 135.4 0.0 3e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Heme oxygenase Asp PF00026.18 EAU86015.1 - 6.9e-25 87.9 0.2 5.9e-24 84.8 0.1 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EAU86015.1 - 8.4e-05 23.0 0.1 0.0051 17.2 0.0 3.1 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 EAU86015.1 - 0.035 13.9 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.18 EAU86016.1 - 6.5e-22 78.1 0.0 1.3e-18 67.3 0.0 3.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EAU86016.1 - 0.00076 19.9 0.1 0.0077 16.7 0.1 2.8 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 EAU86016.1 - 0.097 12.5 0.0 0.36 10.6 0.0 2.0 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4448 PF14610.1 EAU86016.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.5 EAU86016.1 - 0.26 10.6 3.7 0.26 10.6 1.4 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PepSY_TM_2 PF13703.1 EAU86016.1 - 4.1 7.6 6.2 0.64 10.2 0.5 2.4 3 0 0 3 3 3 0 PepSY-associated TM helix DNA_pol_B_exo1 PF03104.14 EAU86017.1 - 1.6e-36 125.8 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.4 EAU86017.1 - 0.0014 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB CheB_methylest PF01339.12 EAU86017.1 - 0.031 13.7 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 CheB methylesterase DNA_pol_B_exo1 PF03104.14 EAU86018.2 - 1e-39 136.3 0.0 1.4e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.4 EAU86018.2 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Dynactin_p62 PF05502.8 EAU86021.1 - 3.2e-55 187.8 0.0 3.2e-54 184.5 0.0 1.9 1 1 0 1 1 1 1 Dynactin p62 family Aminotran_1_2 PF00155.16 EAU86022.1 - 2.8e-28 98.9 0.0 3.4e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EAU86022.1 - 1.8e-08 33.4 0.0 2.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EAU86022.1 - 0.00039 19.5 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_15 PF00723.16 EAU86023.1 - 1.4e-89 300.7 0.0 1.6e-89 300.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EAU86023.1 - 1.7e-27 94.8 0.4 3.8e-27 93.7 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain DUF500 PF04366.7 EAU86024.1 - 7e-44 148.2 0.0 1.1e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) Sec7 PF01369.15 EAU86024.1 - 0.0062 16.2 0.0 0.0092 15.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Phosphodiest PF01663.17 EAU86025.1 - 1.9e-77 261.0 0.4 2.4e-77 260.7 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAU86025.1 - 0.033 13.3 0.0 5.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Sulfatase PAT1 PF09770.4 EAU86026.2 - 1.8 6.7 31.6 2 6.5 21.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gelsolin PF00626.17 EAU86027.2 - 6.4e-28 96.2 0.1 6.7e-15 54.5 0.0 3.5 4 0 0 4 4 4 3 Gelsolin repeat F-box-like PF12937.2 EAU86028.1 - 7.1e-07 28.8 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86028.1 - 5.1e-06 25.9 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF3987 PF13148.1 EAU86029.1 - 5 5.5 7.5 6.5 5.2 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DJ-1_PfpI PF01965.19 EAU86030.2 - 4.2e-22 78.1 0.1 6.8e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EAU86030.2 - 1.7e-08 33.8 0.1 2.9e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Porin_3 PF01459.17 EAU86031.2 - 9.3e-66 221.9 0.9 1e-65 221.7 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin mRNA_triPase PF02940.10 EAU86032.1 - 5.7e-49 166.7 0.0 6.9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain NTR2 PF15458.1 EAU86033.2 - 3.5e-65 219.7 14.4 3.5e-65 219.7 10.0 2.5 3 0 0 3 3 3 1 Nineteen complex-related protein 2 GCFC PF07842.7 EAU86033.2 - 0.014 14.7 0.0 0.15 11.4 0.0 2.2 1 1 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein Rad60-SLD PF11976.3 EAU86034.1 - 8.2e-12 44.6 0.0 9.5e-11 41.2 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EAU86034.1 - 0.03 13.7 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family DUF3889 PF13028.1 EAU86034.1 - 0.11 12.1 0.1 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) Acyl-CoA_dh_1 PF00441.19 EAU86035.1 - 1.8e-20 73.6 1.1 3.8e-20 72.5 0.8 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EAU86035.1 - 1.5e-08 34.9 0.1 2.9e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAU86035.1 - 2.3e-06 27.0 0.2 4.1e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EAU86035.1 - 0.035 14.6 0.0 0.082 13.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain 4HBT PF03061.17 EAU86036.1 - 1.7e-12 47.2 0.3 2.4e-12 46.7 0.2 1.1 1 0 0 1 1 1 1 Thioesterase superfamily Asparaginase_2 PF01112.13 EAU86036.1 - 0.016 13.9 0.3 0.021 13.5 0.2 1.1 1 0 0 1 1 1 0 Asparaginase 4HBT_3 PF13622.1 EAU86036.1 - 0.028 14.1 0.1 0.037 13.7 0.1 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily ParA PF10609.4 EAU86037.2 - 1.2e-28 98.8 0.4 2e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EAU86037.2 - 7.9e-17 61.2 0.1 1.4e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EAU86037.2 - 1.1e-06 28.6 0.0 9.6e-06 25.6 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 EAU86037.2 - 0.0004 19.8 0.3 0.00082 18.8 0.2 1.4 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EAU86037.2 - 0.0011 18.1 2.6 0.034 13.1 0.3 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 EAU86037.2 - 0.0015 17.7 0.2 0.0026 16.8 0.0 1.4 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 EAU86037.2 - 0.01 15.4 1.1 0.032 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EAU86037.2 - 0.09 13.5 0.1 0.14 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EAU86037.2 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Alg6_Alg8 PF03155.10 EAU86038.2 - 7.2e-124 414.1 17.7 8.9e-123 410.5 12.3 1.9 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family MRP-L20 PF12824.2 EAU86039.1 - 2.7e-34 118.5 8.2 4.8e-34 117.6 5.7 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Malic_M PF03949.10 EAU86040.2 - 1.4e-86 290.2 0.0 1.8e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EAU86040.2 - 3.2e-65 219.1 0.0 6.3e-65 218.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SET PF00856.23 EAU86041.2 - 4.8e-08 33.4 0.0 9.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 EAU86041.2 - 1.1e-07 31.4 0.0 2.2e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region CBM_X2 PF03442.9 EAU86041.2 - 0.065 13.0 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Glycos_transf_4 PF00953.16 EAU86042.2 - 2.3e-29 102.2 8.2 2.3e-29 102.2 5.7 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 ICL PF00463.16 EAU86043.1 - 3.8e-253 840.4 0.5 4.3e-253 840.2 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EAU86043.1 - 6.1e-10 38.7 0.1 1.8e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EAU86043.1 - 0.044 13.2 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain F-actin_cap_A PF01267.12 EAU86044.1 - 7.5e-95 317.0 0.0 8.8e-95 316.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit PROCN PF08083.6 EAU86045.1 - 6.5e-218 723.1 8.4 1.8e-217 721.6 5.3 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EAU86045.1 - 3.5e-127 422.4 0.7 6.2e-127 421.6 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EAU86045.1 - 4.2e-92 305.7 1.2 9.6e-92 304.5 0.8 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EAU86045.1 - 9.8e-81 268.7 2.7 9.8e-81 268.7 1.8 2.7 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EAU86045.1 - 2.9e-69 230.9 0.1 5.5e-69 230.0 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EAU86045.1 - 1.3e-43 146.7 0.1 3.4e-43 145.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EAU86045.1 - 1.2e-36 125.2 0.0 2.9e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 EAU86045.1 - 7e-05 22.5 0.0 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DAHP_synth_1 PF00793.15 EAU86046.2 - 3.5e-91 304.6 0.0 4.3e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.10 EAU86047.1 - 3.5e-19 67.8 7.1 4.4e-19 67.5 4.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ATLF PF07737.6 EAU86047.1 - 0.022 14.1 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Anthrax toxin lethal factor, N- and C-terminal domain Mmp37 PF09139.6 EAU86047.1 - 0.051 12.5 0.1 0.052 12.5 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Band_7 PF01145.20 EAU86052.2 - 6.6e-19 68.4 0.1 1e-18 67.8 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PQ-loop PF04193.9 EAU86053.2 - 8.4e-35 118.1 8.8 2.2e-18 65.5 1.9 2.7 2 0 0 2 2 2 2 PQ loop repeat F-box-like PF12937.2 EAU86054.1 - 3.6e-09 36.2 0.2 1.5e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like G-patch PF01585.18 EAU86055.2 - 2.1e-06 27.4 0.1 4.8e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 G-patch domain BNIP3 PF06553.7 EAU86055.2 - 0.05 12.9 0.3 0.05 12.9 0.2 2.3 2 0 0 2 2 2 0 BNIP3 Pantoate_transf PF02548.10 EAU86056.1 - 1.1e-100 336.1 0.4 1.3e-100 335.8 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EAU86056.1 - 0.00015 21.0 0.4 0.00049 19.3 0.2 1.9 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DeoC PF01791.4 EAU86056.1 - 0.036 13.3 0.1 0.062 12.5 0.1 1.4 1 0 0 1 1 1 0 DeoC/LacD family aldolase TPR_11 PF13414.1 EAU86058.2 - 4e-17 61.6 0.6 1.6e-10 40.4 0.0 2.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EAU86058.2 - 1.8e-11 43.0 0.8 0.0005 19.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU86058.2 - 1.5e-07 30.7 1.0 0.0051 16.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU86058.2 - 3.6e-07 30.6 0.3 0.00012 22.6 0.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.2 EAU86058.2 - 1.6e-06 27.7 0.4 3.6e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.1 EAU86058.2 - 7.4e-06 26.1 0.3 0.083 13.5 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU86058.2 - 1.7e-05 25.0 0.0 0.016 15.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU86058.2 - 9.9e-05 22.2 0.2 0.021 14.7 0.8 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU86058.2 - 0.00048 19.7 0.1 0.19 11.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAU86058.2 - 0.0011 19.0 0.2 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAU86058.2 - 0.019 14.8 0.1 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAU86058.2 - 0.08 12.8 1.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 EAU86058.2 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_1 PF00560.28 EAU86058.2 - 0.12 12.5 0.6 11 6.4 0.1 4.2 4 0 0 4 4 3 0 Leucine Rich Repeat LRR_4 PF12799.2 EAU86058.2 - 3 7.5 6.8 31 4.3 0.5 3.8 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAU86058.2 - 5.9 7.5 7.6 43 4.9 0.1 5.1 6 1 0 6 6 4 0 Leucine rich repeat Dockerin_1 PF00404.13 EAU86059.1 - 0.088 12.5 0.6 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 Dockerin type I repeat ABM PF03992.11 EAU86060.2 - 0.0005 20.0 0.0 0.37 10.8 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase BTB PF00651.26 EAU86061.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Lactamase_B PF00753.22 EAU86063.1 - 1.8e-10 40.7 0.7 3.6e-10 39.8 0.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAU86063.1 - 2.3e-06 27.2 0.3 3.1e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAU86064.1 - 5.2e-09 36.0 0.2 3.5e-08 33.3 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAU86064.1 - 6.1e-05 22.6 0.4 9.8e-05 21.9 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ufd2P_core PF10408.4 EAU86067.1 - 1.5e-185 618.1 0.0 1.8e-185 617.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EAU86067.1 - 4.7e-28 96.9 0.5 2.9e-27 94.4 0.3 2.5 2 0 0 2 2 2 1 U-box domain Spore_III_AB PF09548.5 EAU86067.1 - 0.075 12.7 0.4 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_L35p PF01632.14 EAU86068.1 - 8.9e-16 57.5 4.9 1.2e-15 57.1 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 zf-AN1 PF01428.11 EAU86069.1 - 2.6e-20 72.0 30.2 8.5e-12 44.7 5.1 2.7 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EAU86069.1 - 0.00055 20.0 20.0 0.088 13.0 4.4 2.6 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.16 EAU86069.1 - 7.7 6.4 26.6 3.7 7.5 7.3 3.2 1 1 1 2 2 2 0 IBR domain zf-Sec23_Sec24 PF04810.10 EAU86069.1 - 8.5 6.0 13.1 1.7 8.2 0.5 3.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger His_Phos_1 PF00300.17 EAU86070.1 - 2.9e-23 82.7 0.0 4.1e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2487 PF10673.4 EAU86070.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Eaf7 PF07904.8 EAU86071.1 - 4.5e-15 55.3 0.0 7.4e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 CAP_N PF01213.14 EAU86071.1 - 5.4 6.2 7.5 1 8.5 1.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Cyclin_N PF00134.18 EAU86072.2 - 1.1e-09 37.9 0.5 6.4e-09 35.4 0.1 2.4 3 1 0 3 3 3 1 Cyclin, N-terminal domain MBOAT_2 PF13813.1 EAU86073.2 - 2.5e-14 53.1 2.7 2.5e-14 53.1 1.9 2.8 2 1 1 3 3 3 1 Membrane bound O-acyl transferase family NicO PF03824.11 EAU86074.1 - 4.1e-33 114.9 0.0 4.1e-33 114.9 0.0 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein DUF4122 PF13498.1 EAU86074.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) adh_short PF00106.20 EAU86075.2 - 2.5e-11 43.7 0.0 3.3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU86075.2 - 6.6e-08 32.4 0.0 8.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU86075.2 - 0.00026 20.8 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3842 PF12953.2 EAU86075.2 - 0.0099 16.0 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3842) Saccharop_dh PF03435.13 EAU86075.2 - 0.022 13.7 0.1 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase HECT PF00632.20 EAU86077.2 - 2e-94 316.3 0.0 2.7e-94 315.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EAU86077.2 - 1.3e-34 117.6 19.2 8.2e-12 44.7 0.2 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EAU86077.2 - 5.2e-12 45.4 0.0 1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain GPS PF01825.16 EAU86079.2 - 0.2 11.8 1.5 0.31 11.1 1.1 1.3 1 0 0 1 1 1 0 Latrophilin/CL-1-like GPS domain SRF-TF PF00319.13 EAU86081.2 - 1.1e-22 78.9 0.2 1.8e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EAU86081.2 - 0.62 8.0 1.7 0.99 7.3 0.0 1.8 2 0 0 2 2 2 0 CDC45-like protein RasGEF PF00617.14 EAU86082.2 - 3.9e-24 85.4 0.1 1.7e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EAU86082.2 - 5.7e-12 45.6 1.2 1.4e-11 44.3 0.9 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF1235 PF06822.7 EAU86082.2 - 0.013 14.4 0.1 0.026 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) ETC_C1_NDUFA4 PF04800.7 EAU86085.1 - 1.1e-36 124.6 0.1 1.6e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF221 PF02714.10 EAU86086.2 - 3.8e-42 144.3 19.5 1.2e-41 142.6 13.5 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAU86086.2 - 4.1e-12 45.9 1.0 4.1e-12 45.9 0.7 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EAU86086.2 - 2.6e-05 24.6 9.8 0.031 14.8 1.1 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4463) RRM_5 PF13893.1 EAU86086.2 - 0.018 14.9 0.0 0.061 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU86086.2 - 0.029 14.3 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CBM_1 PF00734.13 EAU86087.1 - 2.8e-11 42.8 9.1 2.8e-11 42.8 6.3 2.1 1 1 0 1 1 1 1 Fungal cellulose binding domain AflR PF08493.5 EAU86087.1 - 7.5 5.4 6.2 12 4.7 4.3 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Sod_Cu PF00080.15 EAU86088.1 - 3e-44 150.6 3.5 3.7e-44 150.3 2.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Ribosomal_L1 PF00687.16 EAU86090.1 - 4e-54 183.2 0.5 4e-54 183.2 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF605 PF04652.11 EAU86090.1 - 1e-05 25.1 16.2 1.1e-05 25.0 11.2 1.1 1 0 0 1 1 1 1 Vta1 like Abhydrolase_6 PF12697.2 EAU86091.2 - 1e-10 41.9 0.2 1.4e-10 41.4 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU86091.2 - 7.2e-08 31.8 0.4 1.7e-07 30.6 0.3 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAU86091.2 - 3.7e-07 29.9 0.0 5.2e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU86091.2 - 0.00083 18.9 0.4 0.0043 16.6 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.5 EAU86091.2 - 0.0012 17.7 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF915 PF06028.6 EAU86091.2 - 0.0036 16.4 0.0 0.0092 15.0 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.8 EAU86091.2 - 0.0091 15.4 0.0 0.03 13.7 0.0 1.9 1 1 1 2 2 2 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.21 EAU86092.2 - 8e-23 80.4 0.1 1.4e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU86092.2 - 1.5e-13 51.7 0.3 6.1e-13 49.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU86092.2 - 1.2e-10 41.1 0.1 3.1e-08 33.3 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 EAU86092.2 - 0.0018 18.1 0.5 1.6 8.6 0.0 2.4 1 1 1 2 2 2 2 Dihydrodipicolinate reductase, N-terminus AAA_5 PF07728.9 EAU86094.2 - 2e-115 380.7 0.0 2e-20 72.9 0.0 9.8 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EAU86094.2 - 2.6e-26 91.7 0.0 1.1e-10 41.2 0.0 8.3 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EAU86094.2 - 2.8e-19 69.6 0.3 0.0012 19.0 0.0 7.1 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU86094.2 - 5.6e-19 68.5 0.4 0.01 15.9 0.0 8.1 7 0 0 7 7 6 4 AAA domain Sigma54_activat PF00158.21 EAU86094.2 - 1.5e-17 63.5 0.0 0.0041 16.5 0.0 6.0 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_14 PF13173.1 EAU86094.2 - 2.6e-14 53.1 0.0 0.00076 19.3 0.0 7.4 8 0 0 8 8 6 2 AAA domain Sigma54_activ_2 PF14532.1 EAU86094.2 - 4.1e-13 49.5 0.1 0.00024 21.1 0.0 5.8 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_17 PF13207.1 EAU86094.2 - 4.1e-11 43.7 0.0 0.091 13.5 0.0 6.0 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 EAU86094.2 - 4.9e-11 43.0 0.0 0.5 10.6 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EAU86094.2 - 3.4e-10 40.2 28.4 0.03 14.2 0.3 9.5 9 3 1 10 10 7 4 AAA ATPase domain ABC_tran PF00005.22 EAU86094.2 - 8.3e-10 39.1 0.6 0.12 12.6 0.0 5.8 5 0 0 5 5 5 1 ABC transporter AAA_19 PF13245.1 EAU86094.2 - 4.3e-09 36.0 8.1 0.024 14.3 0.1 5.9 7 0 0 7 7 5 2 Part of AAA domain T2SE PF00437.15 EAU86094.2 - 1.1e-08 34.3 0.6 0.038 12.9 0.0 5.0 6 0 0 6 6 5 3 Type II/IV secretion system protein AAA_33 PF13671.1 EAU86094.2 - 1.3e-08 34.8 0.0 1 9.2 0.0 5.8 5 0 0 5 5 5 2 AAA domain UPF0079 PF02367.12 EAU86094.2 - 6.2e-08 32.3 0.1 0.74 9.4 0.0 5.2 5 0 0 5 5 5 2 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EAU86094.2 - 1.7e-07 30.5 0.2 4.5 6.3 0.0 6.6 7 0 0 7 7 5 0 Zeta toxin MobB PF03205.9 EAU86094.2 - 3.3e-07 30.1 0.8 10 5.8 0.0 5.4 5 0 0 5 5 5 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EAU86094.2 - 5e-07 30.2 0.2 3.9 8.0 0.0 5.6 5 0 0 5 5 5 0 Miro-like protein AAA_29 PF13555.1 EAU86094.2 - 6e-07 28.9 1.0 1.2 8.7 0.0 4.9 5 0 0 5 5 4 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EAU86094.2 - 9e-07 28.2 0.1 1.4 8.0 0.0 6.2 6 0 0 6 6 6 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EAU86094.2 - 2.5e-06 27.3 0.1 0.44 10.1 0.0 5.4 5 0 0 5 5 5 1 Archaeal ATPase NACHT PF05729.7 EAU86094.2 - 3.6e-06 26.7 1.1 3.4 7.2 0.0 5.6 5 0 0 5 5 5 0 NACHT domain AAA_28 PF13521.1 EAU86094.2 - 1e-05 25.5 1.8 1.3 9.0 0.0 5.4 6 0 0 6 6 5 1 AAA domain RNA_helicase PF00910.17 EAU86094.2 - 2.8e-05 24.2 0.5 23 5.1 0.0 5.6 6 0 0 6 6 5 0 RNA helicase DUF815 PF05673.8 EAU86094.2 - 4.4e-05 22.5 0.0 1.5 7.6 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EAU86094.2 - 0.00017 20.7 0.1 2.4 7.1 0.0 3.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 EAU86094.2 - 0.00071 19.0 0.3 11 5.3 0.0 4.4 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain DUF258 PF03193.11 EAU86094.2 - 0.00071 18.7 0.3 0.65 9.1 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAU86094.2 - 0.0015 18.0 1.4 21 4.4 0.1 5.3 5 0 0 5 5 5 0 AAA domain IstB_IS21 PF01695.12 EAU86094.2 - 0.0017 17.7 0.0 2.8 7.3 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein PduV-EutP PF10662.4 EAU86094.2 - 0.0019 17.6 0.9 0.55 9.7 0.0 3.9 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.24 EAU86094.2 - 0.0028 17.1 0.3 9.1 5.7 0.0 4.1 4 0 0 4 4 3 0 DEAD/DEAH box helicase ResIII PF04851.10 EAU86094.2 - 0.0053 16.5 0.0 8.6 6.1 0.0 3.7 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 EAU86094.2 - 0.017 15.0 0.2 6.8 6.6 0.0 4.1 5 0 0 5 5 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EAU86094.2 - 0.038 13.7 1.2 19 4.8 0.0 4.1 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.1 EAU86094.2 - 0.045 13.3 0.1 43 3.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain Bac_DnaA PF00308.13 EAU86094.2 - 0.067 12.8 0.0 6.9 6.2 0.0 3.3 3 0 0 3 3 3 0 Bacterial dnaA protein vWA-TerF-like PF10138.4 EAU86094.2 - 0.081 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 vWA found in TerF C terminus Gtr1_RagA PF04670.7 EAU86094.2 - 0.11 11.5 0.5 0.82 8.7 0.0 2.7 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region PhoH PF02562.11 EAU86094.2 - 0.14 11.3 0.3 42 3.2 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein KaiC PF06745.8 EAU86094.2 - 0.19 10.8 0.8 29 3.6 0.0 3.9 5 0 0 5 5 3 0 KaiC ATP_bind_1 PF03029.12 EAU86094.2 - 0.27 10.7 1.9 13 5.2 0.0 3.4 4 0 0 4 4 2 0 Conserved hypothetical ATP binding protein cobW PF02492.14 EAU86094.2 - 0.44 9.9 2.3 25 4.2 0.0 4.4 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EAU86094.2 - 0.6 10.4 17.4 5.9 7.1 0.0 5.8 7 0 0 7 7 4 0 AAA domain TIP49 PF06068.8 EAU86094.2 - 1 8.0 0.2 19 3.8 0.0 2.9 3 0 0 3 3 3 0 TIP49 C-terminus AAA_6 PF12774.2 EAU86094.2 - 1.8 8.0 0.0 1.1e+02 2.2 0.0 3.6 4 0 0 4 4 4 0 Hydrolytic ATP binding site of dynein motor region D1 tRNA-synt_1d PF00750.14 EAU86095.1 - 7.6e-87 291.4 2.2 1.1e-86 290.9 1.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EAU86095.1 - 8.9e-21 74.0 0.0 2.3e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain DUF2250 PF10007.4 EAU86095.1 - 0.0034 17.2 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2250) ORC4_C PF14629.1 EAU86095.1 - 0.038 13.3 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus AAA_15 PF13175.1 EAU86095.1 - 0.044 12.8 0.1 0.069 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain F-box-like PF12937.2 EAU86096.1 - 4.7e-10 39.0 0.2 1.1e-09 37.8 0.2 1.7 1 0 0 1 1 1 1 F-box-like DUF3368 PF11848.3 EAU86096.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) COPI_C PF06957.6 EAU86096.1 - 0.66 8.4 3.6 0.97 7.8 2.5 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus AAA PF00004.24 EAU86097.1 - 7.9e-40 136.1 0.0 1.6e-39 135.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU86097.1 - 3.8e-05 23.7 0.2 0.0028 17.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EAU86097.1 - 0.00034 20.5 0.0 0.0016 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EAU86097.1 - 0.00039 20.1 0.0 0.0024 17.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU86097.1 - 0.0015 18.6 0.4 0.034 14.2 0.3 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAU86097.1 - 0.0028 16.7 0.0 0.0057 15.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAU86097.1 - 0.0045 17.7 0.0 0.014 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EAU86097.1 - 0.006 15.8 0.1 0.048 12.8 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EAU86097.1 - 0.0069 16.1 0.1 0.018 14.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EAU86097.1 - 0.01 15.2 0.1 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EAU86097.1 - 0.014 14.5 0.1 0.036 13.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EAU86097.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAU86097.1 - 0.037 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAU86097.1 - 0.042 13.2 1.4 0.44 9.9 0.1 2.4 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EAU86097.1 - 0.049 13.2 2.9 0.23 11.0 0.1 2.6 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EAU86097.1 - 0.08 11.8 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NuA4 PF09340.5 EAU86098.1 - 2.6e-24 84.6 0.4 2.6e-24 84.6 0.3 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Mod_r PF07200.8 EAU86099.2 - 1.9e-25 89.5 9.1 7.7e-20 71.3 4.0 2.0 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.1 EAU86099.2 - 0.022 14.7 3.7 0.04 13.8 2.5 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Hypoth_Ymh PF09509.5 EAU86099.2 - 0.14 11.7 1.1 1.6 8.3 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (Hypoth_ymh) APG6 PF04111.7 EAU86099.2 - 0.31 10.0 3.9 0.44 9.5 2.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Ribosomal_L6e_N PF03868.10 EAU86099.2 - 0.37 10.7 1.4 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L6, N-terminal domain Glyco_hydro_61 PF03443.9 EAU86100.1 - 1.2e-64 218.1 0.0 1.5e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAU86100.1 - 1.2e-13 50.4 8.1 1.2e-13 50.4 5.6 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Pkinase PF00069.20 EAU86101.2 - 3e-43 147.8 0.0 3e-32 111.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86101.2 - 5.8e-31 107.4 0.0 1.7e-26 92.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAU86101.2 - 0.004 16.1 0.0 0.34 9.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EAU86101.2 - 0.23 10.7 0.0 0.46 9.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family SWI-SNF_Ssr4 PF08549.5 EAU86102.1 - 1.5e-14 53.3 0.9 5.4e-10 38.2 0.0 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1750) DUF1192 PF06698.6 EAU86102.1 - 0.0012 18.5 0.3 0.0034 17.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) HeLo PF14479.1 EAU86102.1 - 0.29 10.8 4.7 0.41 10.3 3.3 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation F-box-like PF12937.2 EAU86103.2 - 5.3e-05 22.8 0.2 0.00014 21.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86103.2 - 0.0016 18.0 3.6 0.0051 16.4 0.1 3.1 3 0 0 3 3 3 1 F-box domain UAA PF08449.6 EAU86104.1 - 1.9e-65 220.7 8.7 2.2e-62 210.6 4.9 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EAU86104.1 - 2.5e-09 37.2 19.0 1.8e-08 34.5 5.1 3.6 4 0 0 4 4 4 2 EamA-like transporter family TPT PF03151.11 EAU86104.1 - 0.00023 20.8 10.9 0.0017 17.9 4.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EAU86104.1 - 0.00075 18.6 5.2 0.12 11.4 0.5 2.9 2 2 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EAU86104.1 - 0.0013 18.9 25.1 0.0016 18.6 5.6 3.8 3 1 0 4 4 4 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 EAU86104.1 - 0.34 10.7 3.4 2.8 7.7 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DSPc PF00782.15 EAU86105.2 - 1.6e-24 85.9 0.0 2.3e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EAU86105.2 - 0.0056 15.5 0.0 0.0067 15.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase SGS PF05002.10 EAU86105.2 - 0.029 14.1 0.1 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 SGS domain Y_phosphatase PF00102.22 EAU86105.2 - 0.032 13.5 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase cobW PF02492.14 EAU86106.2 - 2.2e-41 141.2 0.0 3.1e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EAU86106.2 - 7.3e-05 22.2 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain CobW_C PF07683.9 EAU86106.2 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.1 EAU86106.2 - 0.0025 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU86106.2 - 0.0049 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EAU86106.2 - 0.0061 16.0 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain Arf PF00025.16 EAU86106.2 - 0.01 15.0 0.1 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Arch_ATPase PF01637.13 EAU86106.2 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 EAU86106.2 - 0.012 15.5 0.0 0.041 13.8 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EAU86106.2 - 0.015 15.0 0.1 0.056 13.1 0.0 2.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EAU86106.2 - 0.034 12.9 0.0 0.21 10.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EAU86106.2 - 0.039 14.2 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EAU86106.2 - 0.072 12.5 0.0 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 EAU86106.2 - 0.073 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EAU86106.2 - 0.088 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EAU86106.2 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DNA_pol_E_B PF04042.11 EAU86107.1 - 1.3e-31 109.4 0.1 2.3e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 EAU86107.1 - 6.1e-27 94.7 2.4 1.3e-22 80.5 1.7 2.4 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DUF4131 PF13567.1 EAU86107.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Endosulfine PF04667.12 EAU86108.2 - 4.2e-20 71.5 0.0 8.4e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Pkinase PF00069.20 EAU86111.2 - 2e-66 223.7 0.0 4.6e-66 222.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86111.2 - 2.2e-36 125.2 0.0 3.6e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EAU86111.2 - 1.8e-20 72.3 29.0 1.1e-11 44.2 7.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.11 EAU86111.2 - 8.7e-16 57.4 16.2 2.7e-14 52.6 2.9 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.19 EAU86111.2 - 5.1e-10 39.7 0.2 1.3e-09 38.3 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EAU86111.2 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Peptidase_M64 PF09471.5 EAU86114.2 - 0.0012 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 IgA Peptidase M64 EHN PF06441.7 EAU86115.1 - 2.9e-32 110.9 3.5 6.6e-32 109.7 0.0 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.15 EAU86115.1 - 3.3e-10 39.9 0.0 4.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU86115.1 - 1.2e-09 38.4 0.8 2.7e-09 37.2 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU86115.1 - 0.074 12.8 0.2 0.27 11.0 0.1 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.2 EAU86116.2 - 7.8e-07 28.7 1.3 2.3e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 F-box-like DNA_pol_B_exo1 PF03104.14 EAU86117.2 - 6e-35 120.6 0.0 6.9e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.4 EAU86117.2 - 0.094 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Methyltransf_33 PF10017.4 EAU86119.2 - 1.5e-32 112.1 0.1 2.2e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Glyco_hydro_15 PF00723.16 EAU86122.2 - 7.9e-90 301.5 0.0 9.2e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EAU86122.2 - 6.3e-20 70.5 0.0 1.4e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain zf-RING_2 PF13639.1 EAU86123.1 - 3.6e-14 52.2 3.2 7e-14 51.3 2.3 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EAU86123.1 - 4.5e-10 39.1 0.0 8.3e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EAU86123.1 - 2.4e-07 30.7 3.2 6.2e-07 29.4 2.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EAU86123.1 - 6.5e-07 28.9 1.6 1.4e-06 27.9 1.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAU86123.1 - 4e-06 26.7 3.7 4e-06 26.7 2.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU86123.1 - 5.2e-06 26.0 2.0 9.8e-06 25.1 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU86123.1 - 7.3e-05 22.3 2.2 0.00014 21.4 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAU86123.1 - 0.011 15.5 2.8 0.036 13.8 1.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EAU86123.1 - 0.17 11.9 3.2 0.95 9.4 2.2 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EAU86123.1 - 0.24 10.9 2.3 0.52 9.8 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PAS_3 PF08447.6 EAU86124.2 - 1.5e-07 31.4 0.0 3.6e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EAU86124.2 - 0.00016 21.4 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EAU86124.2 - 0.0025 17.7 0.0 0.008 16.1 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 EAU86124.2 - 0.0037 17.6 0.0 0.06 13.7 0.0 2.8 2 2 1 3 3 3 1 PAS domain PAS_4 PF08448.5 EAU86124.2 - 0.02 14.8 0.0 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 PAS fold RCC1_2 PF13540.1 EAU86124.2 - 0.074 12.6 0.1 0.3 10.7 0.1 2.0 1 1 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Abhydrolase_6 PF12697.2 EAU86125.1 - 1.4e-31 110.1 0.0 2.6e-31 109.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU86125.1 - 1.9e-14 53.6 0.0 4.2e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU86125.1 - 3.1e-14 53.0 0.0 3.7e-13 49.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAU86125.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF1100 PF06500.6 EAU86125.1 - 0.041 12.4 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF676 PF05057.9 EAU86125.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Aldolase_II PF00596.16 EAU86126.2 - 2.4e-38 131.6 0.0 2.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.24 EAU86127.2 - 3.3e-23 82.0 0.0 1.9e-22 79.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU86127.2 - 4.4e-18 64.9 0.0 1.1e-14 54.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EAU86127.2 - 0.0027 17.5 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAU86127.2 - 0.036 12.8 0.0 0.063 12.0 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 EAU86127.2 - 0.1 11.1 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Fasciclin PF02469.17 EAU86128.1 - 9.7e-42 141.9 0.1 1.7e-23 83.0 0.1 2.4 2 1 0 2 2 2 2 Fasciclin domain Abhydrolase_3 PF07859.8 EAU86130.1 - 1.6e-15 57.2 0.0 9.3e-11 41.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU86130.1 - 6.6e-12 45.3 0.0 1.2e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU86130.1 - 3.3e-07 29.7 0.2 0.00074 18.7 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAU86130.1 - 2e-06 27.8 0.0 3.8e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EAU86130.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 EAU86130.1 - 0.18 11.2 0.0 0.56 9.6 0.0 1.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EAU86131.2 - 2.3e-07 30.2 0.0 0.0062 15.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EAU86131.2 - 2.6e-07 30.4 0.0 0.00025 20.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU86131.2 - 1e-05 25.3 0.0 7.8e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EAU86131.2 - 0.033 13.4 0.2 2.5 7.3 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family MFS_1 PF07690.11 EAU86134.2 - 8.3e-16 57.6 47.1 4e-11 42.2 17.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily GntR PF00392.16 EAU86135.2 - 0.053 12.9 0.0 0.86 9.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family zf-MYND PF01753.13 EAU86136.2 - 0.00024 20.9 1.8 0.00051 19.8 1.2 1.5 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 EAU86137.2 - 3e-07 30.0 0.3 3e-07 30.0 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU86137.2 - 1.4e-05 24.5 1.5 0.00014 21.4 1.1 2.6 1 1 0 1 1 1 1 F-box domain Smac_DIABLO PF09057.5 EAU86137.2 - 0.14 11.2 0.2 0.23 10.5 0.2 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases A_deaminase PF00962.17 EAU86138.2 - 7.6e-111 370.1 0.1 1.1e-110 369.7 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2235 PF09994.4 EAU86139.2 - 1.6e-76 257.3 0.0 1.9e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EAU86139.2 - 0.032 13.9 0.0 0.065 12.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 EAU86139.2 - 0.046 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal zf-MYND PF01753.13 EAU86142.2 - 1.2e-08 34.7 13.7 2.5e-08 33.6 9.5 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU86142.2 - 0.17 11.7 4.8 0.39 10.6 3.3 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.6 EAU86142.2 - 0.61 9.6 5.8 4.3 6.9 1.0 2.8 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DUF4066 PF13278.1 EAU86143.1 - 2.3e-20 72.5 0.0 2.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAU86143.1 - 1.2e-09 37.7 0.0 1.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Dynamin_N PF00350.18 EAU86144.1 - 1.3e-17 64.1 0.7 3.4e-17 62.7 0.1 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EAU86144.1 - 1.8e-11 43.9 0.1 1e-10 41.5 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU86144.1 - 1.2e-09 37.9 0.2 4.3e-09 36.0 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EAU86144.1 - 0.00022 21.7 0.3 0.011 16.1 0.2 2.7 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 EAU86144.1 - 0.00049 19.5 0.1 0.039 13.3 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.8 EAU86144.1 - 0.0023 16.8 0.0 0.0044 15.8 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EAU86144.1 - 0.0076 15.7 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arf PF00025.16 EAU86144.1 - 0.03 13.5 0.3 7.8 5.7 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family adh_short PF00106.20 EAU86146.2 - 1.8e-17 63.7 0.0 3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU86146.2 - 1.9e-06 27.6 0.1 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU86146.2 - 0.00059 19.6 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EAU86146.2 - 0.05 12.4 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_10 PF13374.1 EAU86147.2 - 4.7e-38 128.0 3.8 7.3e-05 22.5 0.0 12.2 11 1 1 12 12 12 9 Tetratricopeptide repeat TPR_12 PF13424.1 EAU86147.2 - 1.2e-35 121.3 0.5 1.3e-05 24.9 0.0 11.9 5 3 6 11 11 11 8 Tetratricopeptide repeat CHAT PF12770.2 EAU86147.2 - 8e-27 94.0 0.0 1.7e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EAU86147.2 - 6.3e-18 64.2 7.6 0.007 15.9 0.1 10.2 3 1 8 12 12 12 8 TPR repeat TPR_17 PF13431.1 EAU86147.2 - 1.3e-13 49.9 9.7 1.2 9.4 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAU86147.2 - 0.00032 21.2 1.2 0.35 11.5 0.1 5.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU86147.2 - 0.034 14.0 8.5 1.5e+02 2.6 0.0 9.2 11 1 1 12 12 12 0 Tetratricopeptide repeat Flu_NS2 PF00601.14 EAU86147.2 - 0.04 14.1 0.0 1.8 8.7 0.0 3.6 4 0 0 4 4 4 0 Influenza non-structural protein (NS2) TPR_1 PF00515.23 EAU86147.2 - 0.048 13.2 21.7 70 3.2 0.0 12.1 16 1 1 17 17 17 0 Tetratricopeptide repeat F-box-like PF12937.2 EAU86148.1 - 1.3e-07 31.2 3.2 3.8e-07 29.7 2.2 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU86148.1 - 0.75 9.4 3.5 23 4.7 0.1 3.3 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Nipped-B_C PF12830.2 EAU86150.2 - 1e-35 123.0 0.6 6.7e-35 120.4 0.5 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EAU86150.2 - 1.7e-13 50.1 0.6 2e-11 43.6 0.1 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EAU86150.2 - 0.00034 20.8 1.9 0.0034 17.6 0.2 3.4 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 EAU86150.2 - 0.00072 19.4 0.1 0.41 10.8 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat FANCI_S2 PF14676.1 EAU86150.2 - 0.011 15.6 2.2 0.071 13.0 0.1 3.0 3 0 0 3 3 3 0 FANCI solenoid 2 HA2 PF04408.18 EAU86151.2 - 1.5e-20 73.0 0.0 4.1e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAU86151.2 - 1.2e-13 50.8 0.0 2.9e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAU86151.2 - 5.2e-11 42.2 0.0 1.7e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU86151.2 - 1e-07 31.5 0.1 2e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU86151.2 - 0.00044 20.3 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU86151.2 - 0.015 15.0 0.3 0.04 13.6 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 EAU86151.2 - 0.024 14.3 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.1 EAU86151.2 - 0.039 13.4 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EAU86151.2 - 0.04 13.0 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 EAU86151.2 - 0.055 13.1 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase PhoH PF02562.11 EAU86151.2 - 0.06 12.5 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 EAU86151.2 - 0.076 13.3 0.3 0.82 9.9 0.2 2.3 1 1 0 1 1 1 0 ABC transporter Patatin PF01734.17 EAU86152.2 - 8e-27 94.4 0.1 1.7e-26 93.4 0.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase CN_hydrolase PF00795.17 EAU86153.2 - 3e-16 59.3 0.0 4.4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2235 PF09994.4 EAU86154.2 - 6e-76 255.4 0.0 8.3e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) TPR_10 PF13374.1 EAU86155.1 - 7.1e-30 102.0 17.5 0.00066 19.5 0.0 9.2 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EAU86155.1 - 2.3e-28 97.9 10.9 0.0041 17.0 0.0 9.6 5 3 4 9 9 9 8 Tetratricopeptide repeat CHAT PF12770.2 EAU86155.1 - 2.7e-26 92.3 0.0 5.6e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EAU86155.1 - 7.9e-17 60.6 18.4 0.002 17.7 0.1 9.7 3 1 7 10 10 10 7 TPR repeat TPR_17 PF13431.1 EAU86155.1 - 1.3e-13 49.9 9.3 1.6 9.1 0.0 7.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EAU86155.1 - 2.5e-05 23.8 4.7 1.2e+02 2.9 0.0 9.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU86155.1 - 0.18 11.4 15.3 49 3.7 0.0 9.8 13 0 0 13 13 13 0 Tetratricopeptide repeat Peptidase_C25 PF01364.13 EAU86155.1 - 0.23 10.3 0.0 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C25 Lantibiotic_a PF14867.1 EAU86155.1 - 0.25 10.6 2.1 18 4.6 0.2 2.7 2 0 0 2 2 2 0 Lantibiotic alpha AMPKBI PF04739.10 EAU86156.1 - 3.8e-20 71.6 3.5 3.8e-20 71.6 2.5 2.7 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Pkinase PF00069.20 EAU86157.2 - 1.5e-62 211.1 0.0 2.4e-62 210.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86157.2 - 1.6e-35 122.4 0.0 4.5e-35 120.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU86157.2 - 2.1e-05 23.6 0.0 4.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EAU86157.2 - 0.0027 16.5 0.1 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Avl9 PF09794.4 EAU86163.2 - 4.8e-104 347.8 0.0 1.9e-82 276.7 0.0 2.0 2 0 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EAU86163.2 - 1.6e-10 40.6 0.0 0.00037 20.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EAU86163.2 - 0.00015 21.1 0.8 0.00043 19.6 0.6 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Amino_oxidase PF01593.19 EAU86166.1 - 2.1e-20 73.2 0.3 1.8e-18 66.8 0.1 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAU86166.1 - 3.6e-11 42.9 3.5 1.4e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU86166.1 - 1.5e-07 30.6 8.0 1.2e-05 24.4 0.0 2.9 3 1 0 3 3 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAU86166.1 - 2.1e-07 31.1 2.1 0.015 15.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU86166.1 - 3.9e-05 23.4 5.5 0.015 15.0 0.0 3.0 3 0 0 3 3 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EAU86166.1 - 0.00053 18.5 0.0 0.68 8.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 EAU86166.1 - 0.0031 16.4 0.0 0.32 9.8 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EAU86166.1 - 0.0069 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.10 EAU86166.1 - 0.031 12.4 0.0 3.9 5.5 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.22 EAU86166.1 - 0.056 13.8 1.4 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU86166.1 - 0.082 12.7 0.6 1.5 8.6 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAU86166.1 - 1.2 8.0 3.9 8.1 5.3 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain CHAT PF12770.2 EAU86167.2 - 1.3e-29 103.2 0.0 3e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU86167.2 - 2.3e-13 49.8 12.1 0.027 14.3 0.0 8.2 4 2 5 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAU86167.2 - 3e-08 33.1 6.1 0.32 10.6 0.2 6.7 4 2 3 7 7 7 5 TPR repeat TPR_10 PF13374.1 EAU86167.2 - 3e-07 30.1 11.1 0.00052 19.8 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU86167.2 - 1.8e-05 24.5 2.3 16 5.9 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU86167.2 - 0.49 11.1 16.4 46 5.0 0.0 7.9 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU86167.2 - 3.8 7.2 5.6 34 4.2 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU86168.2 - 2.7e-71 233.6 46.0 1.7e-05 24.5 0.1 15.7 11 3 5 16 16 16 13 Tetratricopeptide repeat TPR_12 PF13424.1 EAU86168.2 - 2.1e-56 187.7 45.0 0.0021 17.9 0.0 16.1 5 4 10 15 15 15 14 Tetratricopeptide repeat TPR_17 PF13431.1 EAU86168.2 - 5.5e-34 113.5 11.5 0.41 10.9 0.0 14.1 13 0 0 13 13 13 11 Tetratricopeptide repeat CHAT PF12770.2 EAU86168.2 - 2.8e-31 108.7 0.0 8.2e-31 107.1 0.0 1.7 2 0 0 2 2 2 1 CHAT domain TPR_11 PF13414.1 EAU86168.2 - 2.7e-25 87.8 39.1 0.0012 18.4 0.0 15.6 5 2 11 17 17 17 9 TPR repeat TPR_16 PF13432.1 EAU86168.2 - 3e-21 75.5 42.7 1 10.1 0.1 16.3 6 3 11 17 17 16 8 Tetratricopeptide repeat Yopt PF09467.5 EAU86168.2 - 5e-08 32.6 1.1 34 4.3 0.0 9.8 12 0 0 12 12 12 0 Hypothetical protein Yopt TPR_2 PF07719.12 EAU86168.2 - 2.4e-05 23.8 28.5 2.4e+02 2.0 0.0 16.2 17 0 0 17 17 17 0 Tetratricopeptide repeat Lantibiotic_a PF14867.1 EAU86168.2 - 0.12 11.6 0.4 32 3.8 0.0 3.4 2 0 0 2 2 2 0 Lantibiotic alpha AAA_10 PF12846.2 EAU86168.2 - 0.16 11.3 6.4 17 4.6 0.2 4.7 1 1 1 3 3 3 0 AAA-like domain Peptidase_C25 PF01364.13 EAU86168.2 - 0.28 10.1 0.0 0.46 9.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 DnaB_bind PF10410.4 EAU86168.2 - 3 7.9 14.9 69 3.5 0.0 8.6 11 0 0 11 11 11 0 DnaB-helicase binding domain of primase zf-MYND PF01753.13 EAU86169.2 - 7.5e-09 35.3 8.5 7.5e-09 35.3 5.9 2.7 2 1 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EAU86169.2 - 0.00018 21.3 2.0 0.00058 19.6 1.4 2.0 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.2 EAU86170.2 - 1.6e-14 53.2 0.7 3.6e-14 52.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86170.2 - 4.1e-05 23.0 0.1 0.00034 20.1 0.1 2.6 2 0 0 2 2 2 1 F-box domain DivIC PF04977.10 EAU86170.2 - 0.0094 15.4 0.9 0.033 13.6 0.8 1.7 2 0 0 2 2 2 1 Septum formation initiator DUF465 PF04325.8 EAU86170.2 - 0.011 15.3 1.9 0.029 14.0 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) FlxA PF14282.1 EAU86170.2 - 0.13 12.2 1.1 0.25 11.3 0.8 1.4 1 0 0 1 1 1 0 FlxA-like protein Ribonuc_red_lgC PF02867.10 EAU86172.2 - 2.5e-210 699.6 0.0 3.4e-210 699.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EAU86172.2 - 3.1e-24 84.5 0.1 8e-24 83.2 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EAU86172.2 - 7.7e-13 48.7 0.1 3.8e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EAU86172.2 - 0.096 10.7 0.0 0.16 10.0 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Aldo_ket_red PF00248.16 EAU86176.2 - 2.5e-41 141.3 0.0 3.1e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_28 PF13518.1 EAU86176.2 - 0.04 13.9 0.3 16 5.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Asparaginase PF00710.15 EAU86176.2 - 0.051 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Asparaginase HTH_Mga PF08280.6 EAU86180.2 - 0.18 11.5 5.7 1.8 8.4 4.0 2.1 1 1 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Pkinase_Tyr PF07714.12 EAU86182.2 - 7.9e-42 143.1 0.0 1.2e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU86182.2 - 4.9e-38 130.7 0.0 7.9e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_10 PF15411.1 EAU86182.2 - 0.00085 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RIO1 PF01163.17 EAU86182.2 - 0.033 13.5 0.0 0.099 11.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family CDC24 PF06395.6 EAU86182.2 - 0.073 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 CDC24 Calponin CH PF00307.26 EAU86184.2 - 1.5e-42 144.0 0.0 1e-23 83.4 0.0 3.2 3 0 0 3 3 3 2 Calponin homology (CH) domain Cofilin_ADF PF00241.15 EAU86184.2 - 1.7e-39 134.5 1.6 1.7e-39 134.5 1.1 2.4 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein EFhand_Ca_insen PF08726.5 EAU86184.2 - 6.9e-14 51.5 0.1 7.9e-13 48.1 0.0 2.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EAU86184.2 - 5.5e-13 48.3 0.0 6.8e-10 38.4 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Syntaxin PF00804.20 EAU86184.2 - 0.0049 16.9 2.4 0.22 11.7 0.1 3.1 1 1 1 2 2 2 1 Syntaxin Tektin PF03148.9 EAU86184.2 - 0.0051 15.4 2.0 0.01 14.4 1.4 1.4 1 0 0 1 1 1 1 Tektin family ApoLp-III PF07464.6 EAU86184.2 - 0.018 15.0 1.6 0.075 13.0 0.1 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) EF-hand_6 PF13405.1 EAU86184.2 - 0.057 13.3 0.0 0.22 11.5 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Glyco_transf_4 PF13439.1 EAU86184.2 - 0.11 12.1 0.1 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Baculo_PEP_C PF04513.7 EAU86184.2 - 0.25 11.1 1.9 0.97 9.2 0.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DMPK_coil PF08826.5 EAU86184.2 - 0.74 9.7 5.9 6.6 6.7 0.1 3.5 3 0 0 3 3 3 0 DMPK coiled coil domain like Spectrin PF00435.16 EAU86184.2 - 2.2 8.5 10.8 2 8.7 1.2 3.8 2 1 2 4 4 4 0 Spectrin repeat SSrecog PF03531.9 EAU86185.2 - 1.7e-64 217.2 0.2 4.5e-64 215.8 0.1 1.8 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EAU86185.2 - 1.1e-23 82.9 0.8 7.1e-22 77.2 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH PF00169.24 EAU86186.1 - 0.00066 19.8 0.3 0.0012 19.0 0.2 1.4 1 0 0 1 1 1 1 PH domain RasGEF PF00617.14 EAU86187.2 - 7.6e-56 188.8 0.1 1.2e-55 188.1 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain adh_short PF00106.20 EAU86188.2 - 6.7e-12 45.6 0.0 1.4e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EAU86188.2 - 5e-06 26.1 0.0 6.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU86188.2 - 2.1e-05 24.6 0.0 5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EAU86188.2 - 3.4e-05 23.5 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EAU86188.2 - 0.0036 16.2 0.0 0.012 14.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EAU86188.2 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 EAU86188.2 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_7 PF13241.1 EAU86188.2 - 0.04 14.1 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 EAU86188.2 - 0.096 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EAU86189.2 - 2.7e-12 46.9 0.0 6.3e-11 42.4 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EAU86189.2 - 0.00019 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EAU86189.2 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EAU86189.2 - 0.004 16.6 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EAU86189.2 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EAU86189.2 - 0.027 13.3 0.0 0.074 11.9 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 EAU86189.2 - 0.039 14.2 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DIOX_N PF14226.1 EAU86190.2 - 1.5e-30 106.0 0.0 3.3e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAU86190.2 - 3.2e-20 72.2 0.0 5.1e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily W_rich_C PF07483.6 EAU86190.2 - 0.12 12.0 0.1 4.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain PrmA PF06325.8 EAU86192.1 - 2.5e-10 39.9 0.0 4.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EAU86192.1 - 7.6e-10 39.3 0.1 1.6e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU86192.1 - 1.9e-09 37.2 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU86192.1 - 2.8e-08 34.1 0.0 5.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU86192.1 - 4.1e-07 30.0 0.0 8.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU86192.1 - 7e-07 29.0 0.0 2.5e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAU86192.1 - 2.1e-05 23.9 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EAU86192.1 - 0.00057 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU86192.1 - 0.00069 20.0 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EAU86192.1 - 0.012 15.2 0.2 0.02 14.4 0.2 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.10 EAU86192.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.15 EAU86192.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EAU86192.1 - 0.025 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.9 EAU86192.1 - 0.035 13.2 0.0 0.071 12.2 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.14 EAU86192.1 - 0.037 13.5 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EAU86192.1 - 0.056 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 EAU86192.1 - 0.065 14.0 0.1 0.25 12.1 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 EAU86192.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CDC27 PF09507.5 EAU86193.1 - 3 6.9 13.7 4.2 6.4 9.4 1.2 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF814 PF05670.8 EAU86194.1 - 1.1e-21 76.4 0.0 2.2e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) RsgI_N PF12791.2 EAU86194.1 - 1.2 8.8 4.0 2.3 7.9 0.6 2.7 2 1 0 2 2 2 0 Anti-sigma factor N-terminus RRM_1 PF00076.17 EAU86195.2 - 3e-09 36.3 0.0 6.7e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU86195.2 - 5.1e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EAU86195.2 - 0.00018 21.5 0.2 0.0006 19.8 0.1 1.9 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 EAU86195.2 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trehalase PF01204.13 EAU86196.1 - 8.8e-109 364.4 0.6 6.3e-98 328.6 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 EAU86196.1 - 0.00052 18.8 0.2 0.0034 16.1 0.0 1.9 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase COesterase PF00135.23 EAU86197.2 - 1.3e-102 344.2 0.0 4.6e-102 342.4 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU86197.2 - 1.1e-06 28.3 0.1 9.1e-06 25.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU86197.2 - 0.00091 18.5 0.1 0.0024 17.1 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Invasin_D3 PF09134.5 EAU86197.2 - 0.13 12.1 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Invasin, domain 3 AAA PF00004.24 EAU86198.2 - 2.3e-39 134.6 0.0 4.8e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAU86198.2 - 3.6e-07 29.4 0.0 9.9e-07 28.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EAU86198.2 - 7.2e-06 26.8 0.0 3.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EAU86198.2 - 4.6e-05 23.3 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EAU86198.2 - 4.8e-05 23.2 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU86198.2 - 5.8e-05 23.2 0.2 0.0019 18.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAU86198.2 - 0.00011 21.8 0.5 0.0015 18.2 0.3 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EAU86198.2 - 0.00018 20.7 0.0 0.00032 19.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EAU86198.2 - 0.0003 20.6 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU86198.2 - 0.00033 20.6 0.2 0.0094 15.9 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EAU86198.2 - 0.00043 19.4 0.3 0.0023 17.1 0.2 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAU86198.2 - 0.00082 19.6 0.1 0.0035 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAU86198.2 - 0.001 18.5 0.9 0.002 17.5 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Rad17 PF03215.10 EAU86198.2 - 0.0011 17.7 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 EAU86198.2 - 0.0013 18.8 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EAU86198.2 - 0.0023 18.0 0.0 0.0062 16.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.1 EAU86198.2 - 0.0035 17.3 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAU86198.2 - 0.0047 16.3 0.9 0.16 11.3 0.2 2.6 2 1 0 3 3 2 1 AAA domain TIP49 PF06068.8 EAU86198.2 - 0.0049 15.6 0.1 0.0087 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 EAU86198.2 - 0.024 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EAU86198.2 - 0.029 13.4 0.0 0.73 8.9 0.0 2.4 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.21 EAU86198.2 - 0.033 13.6 0.0 0.13 11.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 EAU86198.2 - 0.038 13.5 0.0 0.08 12.5 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EAU86198.2 - 0.047 13.3 0.1 0.14 11.8 0.0 1.8 1 1 1 2 2 2 0 NACHT domain Viral_helicase1 PF01443.13 EAU86198.2 - 0.05 13.1 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EAU86198.2 - 0.062 13.6 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter SKI PF01202.17 EAU86198.2 - 0.071 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase IPT PF01745.11 EAU86198.2 - 0.076 12.1 0.1 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase ATP-synt_ab PF00006.20 EAU86198.2 - 0.082 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Guanylate_kin PF00625.16 EAU86198.2 - 0.085 12.2 0.0 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase AAA_10 PF12846.2 EAU86198.2 - 0.091 12.1 0.3 2.2 7.6 0.1 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_19 PF13245.1 EAU86198.2 - 0.11 12.2 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EAU86198.2 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EAU86198.2 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EAU86198.2 - 0.13 11.9 0.0 1.8 8.2 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase PhoH PF02562.11 EAU86198.2 - 0.16 11.2 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Glycos_transf_1 PF00534.15 EAU86200.2 - 5.1e-21 74.8 0.0 1.1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAU86200.2 - 4.1e-09 36.6 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EAU86200.2 - 0.0051 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Tubulin-binding PF00418.14 EAU86200.2 - 0.13 12.0 0.2 0.65 9.7 0.1 2.1 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat FMN_dh PF01070.13 EAU86201.2 - 5.3e-116 387.3 0.0 6.3e-116 387.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EAU86201.2 - 1.6e-06 27.3 0.0 0.019 14.0 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EAU86201.2 - 5.1e-06 25.6 1.5 0.00072 18.5 0.3 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EAU86201.2 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EAU86201.2 - 0.00033 19.9 0.4 0.00054 19.1 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EAU86201.2 - 0.0037 16.5 0.2 0.37 10.0 0.0 2.4 2 0 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EAU86201.2 - 0.14 11.1 0.1 10 5.0 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Sad1_UNC PF07738.8 EAU86202.2 - 3.9e-32 110.8 0.1 7e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Prenyltrans PF00432.16 EAU86203.2 - 5e-38 128.3 4.3 1.4e-12 46.9 0.6 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EAU86203.2 - 1.5e-25 89.7 0.0 2.8e-13 50.2 0.0 2.9 2 1 1 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EAU86203.2 - 1.6e-07 31.3 0.0 0.0042 17.0 0.0 2.4 2 0 0 2 2 2 2 Prenyltransferase-like NOT2_3_5 PF04153.13 EAU86204.2 - 3.6e-31 107.8 0.6 1.1e-30 106.2 0.4 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RNA_pol_Rpb4 PF03874.11 EAU86205.1 - 1.1e-23 83.3 2.9 1.6e-23 82.9 2.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.16 EAU86205.1 - 0.00054 20.0 0.6 0.0016 18.5 0.1 1.9 2 0 0 2 2 2 1 Death effector domain EzrA PF06160.7 EAU86205.1 - 0.056 11.6 2.8 0.053 11.7 0.7 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2525 PF10733.4 EAU86205.1 - 0.092 12.5 0.1 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) ENTH PF01417.15 EAU86208.1 - 6.3e-45 152.0 0.0 9.5e-45 151.4 0.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 EAU86208.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain Glyco_hydro_20 PF00728.17 EAU86209.2 - 2.2e-83 280.3 0.1 2.9e-83 279.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EAU86209.2 - 1.9e-14 54.4 0.0 5.9e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EAU86209.2 - 1.1e-08 35.6 0.0 6.5e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Abhydrolase_6 PF12697.2 EAU86212.1 - 3.2e-27 95.8 0.3 3.9e-27 95.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU86212.1 - 3.2e-12 46.4 0.1 5.1e-12 45.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU86212.1 - 4.4e-10 39.5 0.2 9e-09 35.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EAU86212.1 - 2.6e-05 23.9 0.1 5.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EAU86212.1 - 0.036 12.5 0.1 0.048 12.1 0.1 1.1 1 0 0 1 1 1 0 Ndr family Ser_hydrolase PF06821.8 EAU86212.1 - 0.1 12.2 0.2 14 5.2 0.1 2.8 1 1 0 3 3 3 0 Serine hydrolase Glyco_hydro_20 PF00728.17 EAU86214.2 - 8.5e-87 291.5 0.0 1e-86 291.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EAU86214.2 - 2.3e-15 57.4 0.0 5.6e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EAU86214.2 - 0.00024 21.6 0.0 0.00058 20.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WD40 PF00400.27 EAU86217.2 - 3.4e-06 26.7 4.1 0.00023 20.8 0.0 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat ATP-synt_C PF00137.16 EAU86220.1 - 3.6e-31 106.8 30.2 1.1e-18 66.9 8.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C LRR_6 PF13516.1 EAU86222.1 - 7.3e-11 40.9 7.8 5.4 7.4 0.0 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 EAU86222.1 - 1.2e-08 34.3 10.6 0.0026 17.3 1.3 5.2 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EAU86222.1 - 2.5e-05 23.6 0.6 47 4.5 0.0 6.4 7 0 0 7 7 7 2 Leucine Rich Repeat Aldo_ket_red PF00248.16 EAU86225.1 - 1.2e-54 185.0 0.0 1.5e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Homeobox PF00046.24 EAU86225.1 - 0.013 15.0 0.1 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 Homeobox domain HTH_23 PF13384.1 EAU86225.1 - 0.09 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r3 PF04539.11 EAU86225.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 Methyltransf_11 PF08241.7 EAU86226.2 - 4.1e-11 43.2 0.0 8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU86226.2 - 5.4e-11 42.7 0.0 1.1e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU86226.2 - 3.2e-10 39.9 0.0 5.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU86226.2 - 1.2e-09 38.6 0.0 2.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU86226.2 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU86226.2 - 8.2e-08 31.6 0.0 1.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EAU86226.2 - 5.7e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU86226.2 - 4e-06 27.2 0.0 7.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAU86226.2 - 0.00065 18.8 0.0 0.0019 17.2 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EAU86226.2 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EAU86226.2 - 0.31 10.2 0.0 0.57 9.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Rho_N PF07498.7 EAU86227.2 - 0.00039 20.1 0.3 0.00067 19.3 0.2 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.22 EAU86227.2 - 0.031 13.7 0.1 0.062 12.8 0.1 1.5 1 0 0 1 1 1 0 SAP domain Nitro_FeMo-Co PF02579.12 EAU86227.2 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Peptidase_C48 PF02902.14 EAU86228.2 - 2.7e-34 118.6 0.5 4.6e-33 114.6 0.3 2.4 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Calpain_III PF01067.17 EAU86228.2 - 0.0059 16.2 0.4 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 Calpain large subunit, domain III DivIC PF04977.10 EAU86228.2 - 0.22 11.0 1.2 0.6 9.6 0.9 1.7 1 0 0 1 1 1 0 Septum formation initiator Glyco_transf_28 PF03033.15 EAU86229.2 - 1.1e-21 77.0 0.0 2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EAU86229.2 - 1.5e-06 27.0 0.0 2.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GRAM PF02893.15 EAU86229.2 - 0.0062 16.0 0.0 0.75 9.3 0.0 3.5 4 0 0 4 4 4 1 GRAM domain PH PF00169.24 EAU86229.2 - 0.0083 16.3 0.1 0.056 13.6 0.1 2.2 2 0 0 2 2 2 1 PH domain Pkinase_Tyr PF07714.12 EAU86230.2 - 5.3e-09 35.5 0.3 7.5e-08 31.7 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EAU86230.2 - 1.4e-08 34.1 0.0 2.1e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 EAU86230.2 - 0.0088 15.0 0.4 0.95 8.3 0.1 2.2 1 1 1 2 2 2 2 Kinase-like Exo_endo_phos PF03372.18 EAU86231.2 - 1.2e-12 48.3 0.4 2.4e-12 47.3 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EAU86231.2 - 0.012 15.2 1.3 0.088 12.4 0.4 2.5 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase BLOC1_2 PF10046.4 EAU86233.1 - 0.033 14.3 1.3 0.083 13.0 0.6 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MutS_III PF05192.13 EAU86233.1 - 0.039 13.7 0.7 0.052 13.3 0.5 1.2 1 0 0 1 1 1 0 MutS domain III CHASE3 PF05227.8 EAU86233.1 - 0.051 13.2 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 CHASE3 domain DUF155 PF02582.9 EAU86233.1 - 0.057 13.3 0.1 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Reo_sigmaC PF04582.7 EAU86233.1 - 0.058 12.5 0.1 0.077 12.1 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein RP-C PF03428.8 EAU86233.1 - 0.076 12.4 0.3 0.28 10.6 0.0 2.0 2 1 0 2 2 2 0 Replication protein C N-terminal domain DUF479 PF04336.7 EAU86233.1 - 0.099 12.7 0.1 0.19 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF479 Lectin_N PF03954.9 EAU86233.1 - 0.18 11.1 1.2 0.3 10.4 0.8 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Syntaxin PF00804.20 EAU86233.1 - 0.19 11.9 2.7 0.38 10.9 1.9 1.5 1 1 0 1 1 1 0 Syntaxin PTRF_SDPR PF15237.1 EAU86233.1 - 0.22 10.8 3.7 1.1 8.5 0.1 2.2 1 1 0 2 2 2 0 PTRF/SDPR family Occludin_ELL PF07303.8 EAU86233.1 - 0.24 12.1 1.4 1.2 9.9 1.0 2.0 1 1 0 1 1 1 0 Occludin homology domain Seryl_tRNA_N PF02403.17 EAU86233.1 - 0.65 10.0 4.0 2.7 8.0 2.7 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain POPLD PF08170.7 EAU86234.2 - 1.5e-30 104.8 0.5 3.1e-30 103.8 0.4 1.5 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.6 EAU86234.2 - 2.2e-28 99.2 2.8 1.9e-26 92.8 0.7 2.6 2 0 0 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 GCV_T PF01571.16 EAU86234.2 - 0.0064 15.8 0.1 0.94 8.8 0.0 2.6 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain Nbl1_Borealin_N PF10444.4 EAU86235.2 - 5.4e-10 38.4 0.1 9.7e-10 37.6 0.1 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal 3Beta_HSD PF01073.14 EAU86236.1 - 5e-67 225.5 0.0 2.1e-60 203.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAU86236.1 - 1.3e-33 116.3 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU86236.1 - 2.8e-16 60.0 0.0 4.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EAU86236.1 - 1.6e-14 53.4 0.0 1.8e-12 46.7 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EAU86236.1 - 3.5e-14 52.3 0.0 5.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EAU86236.1 - 6.4e-05 21.9 0.7 0.00016 20.6 0.5 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EAU86236.1 - 0.0042 17.0 0.4 0.12 12.2 0.2 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EAU86236.1 - 0.0066 16.1 0.0 0.02 14.5 0.0 1.7 1 1 1 2 2 2 1 KR domain NmrA PF05368.8 EAU86236.1 - 0.034 13.3 0.3 0.18 11.0 0.2 1.9 1 1 0 1 1 1 0 NmrA-like family D123 PF07065.9 EAU86237.1 - 7.6e-80 268.1 0.0 8.9e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 D123 Glyoxal_oxid_N PF07250.6 EAU86237.1 - 0.04 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus DUF4343 PF14243.1 EAU86237.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) FA_desaturase PF00487.19 EAU86238.1 - 9.6e-24 84.2 24.9 2.1e-23 83.0 17.3 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EAU86238.1 - 0.0043 17.0 0.1 0.0081 16.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF3374 PF11854.3 EAU86238.1 - 0.081 11.1 0.0 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) Pkinase PF00069.20 EAU86239.1 - 5.2e-22 78.2 0.0 7.6e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86239.1 - 4.6e-07 29.1 0.0 2.6e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU86239.1 - 0.03 14.0 0.1 0.19 11.4 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pheromone PF08015.6 EAU86241.2 - 1.3e-05 25.9 1.7 0.00035 21.3 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone TPP_enzyme_N PF02776.13 EAU86242.1 - 1.2e-41 142.0 0.0 1.9e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAU86242.1 - 1.2e-18 67.2 0.0 8.1e-18 64.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EAU86242.1 - 7.6e-16 58.0 0.0 3.1e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1192 PF06698.6 EAU86242.1 - 0.055 13.2 0.0 0.42 10.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DXP_synthase_N PF13292.1 EAU86242.1 - 0.058 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Peptidase_M3 PF01432.15 EAU86243.1 - 4.6e-136 454.5 0.0 6.1e-136 454.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EAU86243.1 - 0.015 14.7 0.2 0.024 14.0 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Usp PF00582.21 EAU86244.2 - 5.3e-20 72.0 0.1 1.9e-19 70.2 0.1 2.0 1 0 0 1 1 1 1 Universal stress protein family Pet127 PF08634.5 EAU86245.2 - 2.5e-102 341.7 0.2 4.8e-102 340.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Arf PF00025.16 EAU86246.1 - 3e-42 143.8 0.0 3.4e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EAU86246.1 - 1.7e-20 73.0 0.0 2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU86246.1 - 3e-11 43.8 0.0 2.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EAU86246.1 - 1.6e-09 37.2 0.0 1.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EAU86246.1 - 2.1e-08 33.6 0.0 2.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU86246.1 - 1.7e-06 27.9 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU86246.1 - 4.6e-06 26.2 0.0 2.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EAU86246.1 - 2.8e-05 22.9 0.2 7.6e-05 21.5 0.1 1.8 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 EAU86246.1 - 0.00013 21.8 0.4 0.059 13.1 0.3 2.2 1 1 1 2 2 2 2 Dynamin family DUF751 PF05421.6 EAU86246.1 - 0.041 14.1 0.3 0.073 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF751) ATP_bind_1 PF03029.12 EAU86246.1 - 0.052 13.0 0.2 7.1 6.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF2205 PF10224.4 EAU86247.1 - 1e-09 37.8 0.4 1.2e-09 37.5 0.3 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EAU86247.1 - 0.0031 17.8 1.2 0.0035 17.6 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Streptin-Immun PF11083.3 EAU86247.1 - 0.099 12.6 0.5 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein HSDR_N PF04313.9 EAU86247.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Proteasom_Rpn13 PF04683.8 EAU86248.1 - 7.6e-27 93.2 0.0 1.2e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor zf-Nse PF11789.3 EAU86249.2 - 1.3e-16 59.8 0.0 2.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EAU86249.2 - 5.7e-05 23.0 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 U-box domain TPR_MLP1_2 PF07926.7 EAU86249.2 - 0.0037 17.0 0.0 0.0072 16.0 0.0 1.5 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Apt1 PF10351.4 EAU86249.2 - 0.016 14.0 0.2 0.025 13.4 0.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-RING_UBOX PF13445.1 EAU86249.2 - 0.044 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DUF148 PF02520.12 EAU86249.2 - 0.052 13.3 1.5 0.69 9.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 zf-RING_2 PF13639.1 EAU86249.2 - 0.055 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EAU86249.2 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BLOC1_2 PF10046.4 EAU86249.2 - 0.74 9.9 4.1 0.71 10.0 0.8 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosom_S12_S23 PF00164.20 EAU86250.2 - 1.2e-44 150.6 3.1 1.5e-44 150.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PH_4 PF15404.1 EAU86251.1 - 5.4e-35 120.5 0.1 6.2e-34 117.1 0.0 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EAU86251.1 - 0.0059 16.7 0.0 7.3 6.8 0.0 3.2 2 1 0 2 2 2 2 PH domain AOX PF01786.12 EAU86252.1 - 2.6e-83 278.5 0.0 3.6e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase HTH_Tnp_Tc5 PF03221.11 EAU86253.2 - 7.3e-16 57.7 0.0 1.4e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EAU86253.2 - 7.9e-06 25.2 0.4 1.8e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.11 EAU86253.2 - 0.00031 19.9 0.2 0.0044 16.2 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 EAU86253.2 - 0.0006 19.3 0.9 0.0015 18.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.2 EAU86253.2 - 0.0015 18.2 0.0 0.0049 16.5 0.0 1.9 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.1 EAU86253.2 - 0.0036 17.0 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.1 EAU86253.2 - 0.0054 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 EAU86253.2 - 0.0063 16.1 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 MarR family HTH_10 PF04967.7 EAU86253.2 - 0.0081 15.7 0.2 0.64 9.6 0.0 2.4 2 0 0 2 2 2 1 HTH DNA binding domain HTH_37 PF13744.1 EAU86253.2 - 0.018 14.8 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.1 EAU86253.2 - 0.042 14.0 0.3 3.8 7.7 0.0 2.9 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.1 EAU86253.2 - 0.044 13.7 1.3 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.14 EAU86253.2 - 0.056 13.1 0.1 0.29 10.8 0.0 2.2 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HTH_3 PF01381.17 EAU86253.2 - 0.062 13.1 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix Sigma70_r3 PF04539.11 EAU86253.2 - 0.08 12.8 0.0 7.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Sigma-70 region 3 HTH_24 PF13412.1 EAU86253.2 - 0.081 12.3 0.0 0.68 9.3 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Phage_terminase PF10668.4 EAU86253.2 - 0.12 12.1 0.3 3.3 7.5 0.1 2.4 2 0 0 2 2 2 0 Phage terminase small subunit Fungal_trans PF04082.13 EAU86254.2 - 1.2e-07 30.9 0.0 1.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU86254.2 - 7.9e-05 22.4 9.5 0.0011 18.8 4.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3639 PF12341.3 EAU86254.2 - 0.12 12.3 0.1 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3639) Tom22 PF04281.8 EAU86255.1 - 5.4e-42 142.5 1.6 6.5e-42 142.3 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.1 EAU86256.1 - 2.8e-17 63.3 0.0 3.7e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAU86256.1 - 1.3e-14 54.0 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EAU86256.1 - 8.2e-13 48.3 0.2 1e-10 41.4 0.2 3.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EAU86256.1 - 2.5e-12 46.2 0.0 1.1e-10 40.9 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EAU86256.1 - 8.8e-10 37.7 0.0 5.2e-09 35.2 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU86256.1 - 1.7e-06 27.1 0.4 0.13 11.1 0.0 3.1 1 1 2 3 3 3 2 Male sterility protein Saccharop_dh PF03435.13 EAU86256.1 - 0.015 14.2 0.0 0.041 12.8 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EAU86256.1 - 0.058 12.2 0.0 0.13 11.1 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein PAP2 PF01569.16 EAU86256.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 PAP2 superfamily DapB_N PF01113.15 EAU86256.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2462 PF09495.5 EAU86257.2 - 4.7e-16 59.2 12.2 6.3e-16 58.8 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF1843 PF08898.5 EAU86257.2 - 0.1 12.6 0.5 0.61 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Herpes_gE PF02480.11 EAU86258.2 - 0.17 10.1 0.0 0.25 9.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Sas10 PF09368.5 EAU86259.1 - 5.6e-23 80.9 8.3 5.6e-23 80.9 5.8 3.5 2 1 1 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EAU86259.1 - 4.4e-09 36.4 0.6 4.4e-09 36.4 0.4 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Fcf2 PF08698.6 EAU86260.1 - 8.5e-19 67.4 0.1 2.2e-18 66.0 0.0 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing AF-4 PF05110.8 EAU86260.1 - 5.5e-05 21.2 9.9 6.3e-05 21.0 6.8 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Trs65 PF12735.2 EAU86260.1 - 0.0049 16.2 0.5 0.0076 15.6 0.4 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 SR-25 PF10500.4 EAU86260.1 - 0.0051 16.3 8.8 0.0051 16.3 6.1 2.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein GEMIN8 PF15348.1 EAU86260.1 - 0.082 12.9 2.7 0.12 12.3 1.9 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CDC45 PF02724.9 EAU86260.1 - 0.54 8.2 13.1 0.78 7.6 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EAU86260.1 - 0.6 8.9 5.4 1.1 8.1 3.7 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cwf_Cwc_15 PF04889.7 EAU86260.1 - 2.1 8.0 22.6 0.22 11.1 11.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2146 PF10220.4 EAU86260.1 - 7.3 4.4 6.7 8.7 4.1 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) MRI PF15325.1 EAU86260.1 - 7.7 7.5 11.8 21 6.1 8.2 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection Ubie_methyltran PF01209.13 EAU86261.2 - 1.7e-79 266.2 0.0 8.4e-79 263.9 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EAU86261.2 - 6.2e-12 45.3 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU86261.2 - 9.6e-12 45.2 0.0 1.7e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU86261.2 - 2.4e-11 43.6 0.0 3.9e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU86261.2 - 2.6e-09 37.3 0.0 5.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU86261.2 - 5.4e-09 36.4 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU86261.2 - 4.6e-08 33.6 0.0 9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU86261.2 - 0.0017 18.3 0.0 0.005 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EAU86261.2 - 0.065 12.8 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Cullin PF00888.17 EAU86262.2 - 2.6e-186 620.6 14.9 3.6e-186 620.2 10.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAU86262.2 - 2.4e-27 94.5 2.5 6.8e-27 93.0 1.7 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain GlnD_UR_UTase PF08335.6 EAU86262.2 - 0.0069 16.2 2.0 0.063 13.1 0.1 2.8 2 1 1 3 3 3 1 GlnD PII-uridylyltransferase HTH_27 PF13463.1 EAU86262.2 - 0.0075 16.5 0.8 7.5 6.9 0.1 3.3 3 0 0 3 3 3 2 Winged helix DNA-binding domain Rrf2 PF02082.15 EAU86262.2 - 0.026 14.6 0.1 0.19 11.8 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulator KAT11 PF08214.6 EAU86263.1 - 1.8e-45 155.5 0.0 2.4e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein K-box PF01486.12 EAU86264.2 - 0.17 11.6 3.9 0.079 12.7 0.6 1.9 2 0 0 2 2 2 0 K-box region Peptidase_S28 PF05577.7 EAU86268.2 - 1.1e-55 188.9 0.0 2.7e-45 154.7 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Rad4 PF03835.10 EAU86269.2 - 1e-21 76.8 9.5 1.6e-21 76.2 0.7 4.0 3 1 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EAU86269.2 - 3.8e-20 71.1 0.1 1.4e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EAU86269.2 - 2e-13 50.4 1.4 5e-12 45.9 0.0 3.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EAU86269.2 - 2.3e-07 31.0 0.0 4.4e-06 26.8 0.0 2.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily GCD14 PF08704.5 EAU86270.1 - 4.5e-94 314.5 0.1 9.6e-92 306.9 0.1 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EAU86270.1 - 1.9e-05 24.6 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU86270.1 - 0.00012 22.6 0.0 0.00023 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAU86270.1 - 0.00015 21.3 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EAU86270.1 - 0.00019 21.0 0.0 0.00062 19.3 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain Peptidase_C37 PF05416.7 EAU86270.1 - 0.07 11.4 0.4 0.1 10.8 0.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Fibrillarin PF01269.12 EAU86270.1 - 0.072 11.9 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin APG6 PF04111.7 EAU86270.1 - 0.076 12.0 3.0 0.11 11.5 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3332 PF11810.3 EAU86270.1 - 0.64 9.6 2.0 0.96 9.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) zf-RING_2 PF13639.1 EAU86271.2 - 5.2e-09 35.8 7.3 3e-08 33.3 5.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAU86271.2 - 7.5e-08 32.3 0.2 1.2e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAU86271.2 - 3.7e-06 26.8 3.7 8.4e-06 25.7 1.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU86271.2 - 9.8e-06 25.1 2.3 1.8e-05 24.3 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU86271.2 - 1.1e-05 25.1 1.2 1.7e-05 24.4 0.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAU86271.2 - 8.2e-05 22.2 1.9 0.00025 20.6 1.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAU86271.2 - 0.0018 18.0 0.2 0.0033 17.2 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EAU86271.2 - 0.011 15.8 0.8 0.021 14.8 0.6 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EAU86271.2 - 0.044 13.5 0.4 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EAU86271.2 - 0.18 11.8 0.7 0.39 10.7 0.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EAU86271.2 - 0.35 10.7 4.3 0.1 12.4 0.7 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Nop PF01798.13 EAU86275.1 - 9.2e-60 200.2 0.0 2.6e-59 198.8 0.0 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EAU86275.1 - 2.4e-26 91.2 0.1 6.2e-26 89.9 0.1 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EAU86275.1 - 9.9e-24 83.2 0.2 9.9e-24 83.2 0.2 3.2 4 0 0 4 4 4 1 NOP5NT (NUC127) domain HEAT_2 PF13646.1 EAU86276.1 - 8.8e-09 35.5 2.0 0.053 13.7 0.0 4.9 4 0 0 4 4 4 2 HEAT repeats IBN_N PF03810.14 EAU86276.1 - 7.5e-07 28.9 0.0 8.1e-06 25.6 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EAU86276.1 - 0.00022 21.1 2.7 0.0082 16.0 0.0 4.1 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EAU86276.1 - 0.0058 16.6 0.2 7.4 6.9 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EAU86276.1 - 0.025 15.0 0.0 1.1 9.8 0.0 3.9 4 0 0 4 4 4 0 HEAT-like repeat hNIFK_binding PF12196.3 EAU86276.1 - 7.8 5.9 8.5 0.11 11.9 0.1 2.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Actin PF00022.14 EAU86278.2 - 3.8e-83 279.0 0.0 4.4e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Actin NRDE PF05742.7 EAU86279.2 - 1.1e-40 139.6 0.0 1.6e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 NRDE protein Zn_clus PF00172.13 EAU86280.1 - 1.3e-08 34.5 7.2 2.8e-08 33.5 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSS PF03034.10 EAU86281.1 - 5.1e-103 344.3 9.3 6.7e-103 343.9 6.5 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase PET PF06297.9 EAU86281.1 - 0.14 11.8 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 PET Domain Kin17_mid PF10357.4 EAU86282.1 - 3.6e-49 165.6 0.7 3.6e-49 165.6 0.5 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EAU86282.1 - 0.00014 21.9 6.2 0.0003 20.8 4.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAU86282.1 - 0.00031 20.8 5.0 0.0007 19.6 3.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAU86282.1 - 0.012 15.7 4.1 0.013 15.5 0.8 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CHB_HEX_C PF03174.8 EAU86283.2 - 0.027 14.3 0.1 0.059 13.2 0.0 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Cellulase PF00150.13 EAU86284.2 - 1.2e-05 24.7 0.0 2.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3703 PF12487.3 EAU86284.2 - 0.2 11.3 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) F-box-like PF12937.2 EAU86285.2 - 0.00014 21.4 0.4 0.00036 20.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU86286.2 - 3.9e-11 42.4 0.5 8.2e-11 41.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86286.2 - 1.3e-05 24.7 0.7 8.7e-05 22.0 0.2 2.4 2 0 0 2 2 2 1 F-box domain AMP-binding PF00501.23 EAU86288.2 - 6e-73 245.6 0.0 8.3e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU86288.2 - 3.5e-08 34.2 0.0 9.5e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-MYND PF01753.13 EAU86289.2 - 1.6e-07 31.0 12.1 3.2e-07 30.0 8.4 1.5 1 0 0 1 1 1 1 MYND finger DUF585 PF04522.7 EAU86289.2 - 0.13 11.6 0.5 0.23 10.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF585) CRAL_TRIO_2 PF13716.1 EAU86290.2 - 9.3e-35 119.7 0.2 1.5e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EAU86290.2 - 2.1e-31 108.5 0.0 3.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EAU86290.2 - 2.3e-05 23.9 0.1 7.4e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain Hist_deacetyl PF00850.14 EAU86292.2 - 2.8e-55 187.8 1.2 3.4e-55 187.5 0.8 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-1_beta_acid PF10587.4 EAU86295.1 - 0.02 15.0 1.3 0.02 15.0 0.9 3.6 5 0 0 5 5 3 0 Eukaryotic elongation factor 1 beta central acidic region Mad3_BUB1_I PF08311.7 EAU86295.1 - 0.05 13.3 0.6 0.13 12.0 0.1 1.9 1 1 0 1 1 1 0 Mad3/BUB1 homology region 1 DUF1043 PF06295.7 EAU86295.1 - 0.15 11.7 2.5 0.23 11.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2935 PF11155.3 EAU86295.1 - 0.15 12.1 6.0 0.75 9.8 1.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF1848 PF08902.6 EAU86295.1 - 0.18 11.3 1.0 0.22 11.0 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1848) NYD-SP28 PF14772.1 EAU86295.1 - 0.21 11.7 9.0 0.14 12.2 4.4 2.1 1 1 0 1 1 1 0 Sperm tail EBV-NA3 PF05009.7 EAU86295.1 - 0.24 10.6 0.1 0.24 10.6 0.1 2.0 1 1 2 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) GAS PF13851.1 EAU86295.1 - 0.41 9.8 14.5 1.3 8.2 9.6 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4559 PF15112.1 EAU86295.1 - 0.44 9.6 6.9 0.55 9.3 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) CM_2 PF01817.16 EAU86295.1 - 0.55 10.3 6.9 0.94 9.6 3.8 2.1 1 1 0 1 1 1 0 Chorismate mutase type II PNPase PF03726.9 EAU86295.1 - 2.8 8.2 7.8 0.66 10.2 2.5 2.1 2 1 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3552 PF12072.3 EAU86297.2 - 0.00092 18.4 9.2 0.00092 18.4 6.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) VHS PF00790.14 EAU86297.2 - 0.039 13.5 1.6 0.043 13.4 0.2 1.7 2 0 0 2 2 2 0 VHS domain CRS1_YhbY PF01985.16 EAU86297.2 - 0.2 11.6 0.6 0.52 10.3 0.4 1.6 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain SPX PF03105.14 EAU86297.2 - 1.2 8.8 7.6 0.033 13.9 0.4 2.0 3 0 0 3 3 3 0 SPX domain F-box-like PF12937.2 EAU86298.2 - 0.0021 17.7 0.6 0.0084 15.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like Mito_carr PF00153.22 EAU86299.1 - 3.4e-60 199.7 8.4 8.5e-21 73.4 0.2 3.7 2 1 1 3 3 3 3 Mitochondrial carrier protein tRNA_int_end_N2 PF12928.2 EAU86300.1 - 5.6e-23 80.1 0.0 1.1e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EAU86300.1 - 0.0023 17.4 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Asp PF00026.18 EAU86301.1 - 1.4e-28 100.1 0.0 1.9e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAU86301.1 - 3.5e-06 27.0 0.2 1.4e-05 25.0 0.2 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAU86301.1 - 0.006 17.0 0.2 0.19 12.2 0.0 2.7 2 1 0 2 2 2 1 Aspartyl protease p450 PF00067.17 EAU86303.2 - 3e-29 101.8 0.0 4.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHAT PF12770.2 EAU86304.2 - 4.2e-25 88.4 0.0 8.5e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU86304.2 - 1.9e-16 59.7 0.1 0.2 11.6 0.0 8.4 3 3 6 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.1 EAU86304.2 - 0.00014 21.7 9.4 0.61 10.1 0.0 6.4 5 1 0 5 5 5 3 Tetratricopeptide repeat Amino_oxidase PF01593.19 EAU86305.1 - 9.5e-15 54.6 0.0 7.8e-12 44.9 0.0 3.0 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAU86305.1 - 1.1e-13 51.0 0.0 4.5e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAU86305.1 - 3.8e-05 23.8 0.1 0.002 18.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU86305.1 - 3.8e-05 22.7 0.2 0.001 18.0 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAU86305.1 - 0.00012 21.8 0.0 0.22 11.2 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EAU86305.1 - 0.0019 18.1 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF1918 PF08940.6 EAU86305.1 - 0.026 13.8 0.0 0.068 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Thi4 PF01946.12 EAU86305.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_4 PF01565.18 EAU86306.2 - 6.6e-12 45.0 0.3 1.8e-11 43.7 0.1 1.8 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EAU86306.2 - 2.7e-10 39.9 1.0 8.2e-10 38.4 0.7 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EAU86306.2 - 0.0023 17.0 0.1 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DcpS PF05652.7 EAU86307.2 - 9e-23 80.7 0.0 2.9e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EAU86307.2 - 4.5e-18 65.5 0.8 1.7e-17 63.6 0.6 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GlutR_dimer PF00745.15 EAU86307.2 - 0.02 14.7 0.1 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain NPR3 PF03666.8 EAU86308.2 - 0.68 8.3 5.9 1 7.8 4.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ORC6 PF05460.8 EAU86308.2 - 2.5 7.1 10.1 4 6.4 7.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) XPG_I PF00867.13 EAU86309.2 - 1.8e-28 98.4 0.0 3.8e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAU86309.2 - 1.5e-19 70.1 0.0 3.8e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EAU86309.2 - 1.1e-06 28.8 1.1 2e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold RR_TM4-6 PF06459.7 EAU86309.2 - 0.00022 21.2 14.5 0.00022 21.2 10.1 2.5 3 0 0 3 3 3 1 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EAU86309.2 - 0.76 7.7 14.0 1.4 6.8 9.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2201_N PF13203.1 EAU86309.2 - 1.3 8.1 9.0 0.91 8.6 3.1 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain DDHD PF02862.12 EAU86309.2 - 2.2 8.0 5.9 0.42 10.3 1.0 2.0 2 0 0 2 2 2 0 DDHD domain Spore_coat_CotO PF14153.1 EAU86309.2 - 2.4 7.5 14.3 1.5 8.2 6.7 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Adeno_E4_34 PF04528.8 EAU86310.1 - 0.021 14.4 1.1 0.04 13.5 0.8 1.4 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Benyvirus_14KDa PF07255.6 EAU86310.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Benyvirus 14KDa protein DUF2583 PF10762.4 EAU86311.2 - 0.17 12.0 2.9 6.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) FAD_binding_4 PF01565.18 EAU86312.2 - 1.3e-16 60.3 3.0 7.9e-10 38.3 1.0 3.0 2 1 1 3 3 3 2 FAD binding domain BBE PF08031.7 EAU86312.2 - 1.3e-08 34.5 0.3 2.9e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like VHS PF00790.14 EAU86313.2 - 2.3e-07 30.5 0.4 4e-07 29.7 0.3 1.3 1 0 0 1 1 1 1 VHS domain RasGAP_C PF03836.10 EAU86313.2 - 0.0091 15.6 0.4 0.018 14.7 0.3 1.4 1 0 0 1 1 1 1 RasGAP C-terminus DUF3552 PF12072.3 EAU86313.2 - 0.013 14.6 13.1 0.026 13.7 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4337 PF14235.1 EAU86313.2 - 1.6 8.5 4.6 3.1 7.6 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Mnd1 PF03962.10 EAU86313.2 - 2.2 7.8 8.2 0.54 9.8 3.4 1.6 2 0 0 2 2 2 0 Mnd1 family p450 PF00067.17 EAU86314.2 - 7.2e-47 159.9 0.0 2e-24 85.9 0.1 2.4 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EAU86315.2 - 1.6e-56 191.7 0.1 2.8e-29 101.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 FolB PF02152.13 EAU86317.2 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Dihydroneopterin aldolase BTB PF00651.26 EAU86319.2 - 0.023 14.7 0.0 0.059 13.3 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain zf-C4pol PF14260.1 EAU86319.2 - 0.11 12.5 0.5 0.26 11.2 0.3 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta WES_acyltransf PF03007.11 EAU86320.2 - 0.079 12.5 0.6 0.093 12.2 0.4 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain 2OG-FeII_Oxy_3 PF13640.1 EAU86321.1 - 5.9e-13 49.1 0.1 1.5e-12 47.9 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EAU86321.1 - 4.8e-05 22.9 0.1 8.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EAU86321.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 EAU86321.1 - 0.0013 17.5 0.0 0.0021 16.8 0.0 1.4 1 1 0 1 1 1 1 Poxvirus C4/C10 protein Sen15 PF09631.5 EAU86322.2 - 1.6e-16 60.3 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Sen15 protein NAD_binding_10 PF13460.1 EAU86323.1 - 8.3e-16 58.5 0.0 2.7e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAU86323.1 - 1e-05 24.9 0.0 3.5e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EAU86323.1 - 0.042 13.7 0.6 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Tyrosinase PF00264.15 EAU86324.1 - 4.9e-39 134.7 0.0 7.5e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF4349 PF14257.1 EAU86325.1 - 0.057 12.6 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) F-box-like PF12937.2 EAU86328.2 - 2.5e-12 46.3 0.5 8.2e-12 44.6 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU86328.2 - 0.0013 18.3 0.0 0.0048 16.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain Abhydrolase_3 PF07859.8 EAU86329.2 - 7.3e-17 61.6 0.0 2e-13 50.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU86329.2 - 4.3e-11 42.4 0.0 5.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAU86329.2 - 8.9e-11 41.7 0.0 1.9e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU86329.2 - 1e-05 25.5 0.1 3.1e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAU86329.2 - 0.012 15.0 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EAU86329.2 - 0.056 12.7 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EAU86329.2 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein FYRC PF05965.9 EAU86330.1 - 8.7e-18 63.9 0.0 3e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.9 EAU86330.1 - 1.1e-16 60.0 0.3 2.1e-16 59.1 0.2 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus Laminin_II PF06009.7 EAU86330.1 - 0.052 13.3 1.4 0.11 12.2 1.0 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF573 PF04504.9 EAU86330.1 - 0.17 12.1 0.4 0.34 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 IncA PF04156.9 EAU86330.1 - 3.6 7.1 5.5 6.2 6.3 3.8 1.2 1 0 0 1 1 1 0 IncA protein SIR2 PF02146.12 EAU86331.2 - 1.7e-60 203.8 0.0 2.3e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-LYAR PF08790.6 EAU86331.2 - 0.03 14.0 0.1 0.052 13.2 0.1 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger TPP_enzyme_M PF00205.17 EAU86331.2 - 0.035 13.8 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF3043 PF11241.3 EAU86333.1 - 2 7.9 5.1 0.36 10.4 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) Gypsy PF07253.6 EAU86335.1 - 0.075 11.3 0.1 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Gypsy protein DUF2721 PF11026.3 EAU86335.1 - 1.6 8.3 14.1 0.54 9.8 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) TraP PF07296.6 EAU86336.2 - 0.11 11.4 2.5 6.4 5.6 0.0 2.3 2 0 0 2 2 2 0 TraP protein FAD-oxidase_C PF02913.14 EAU86338.2 - 1.9e-57 194.4 0.1 2.6e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EAU86338.2 - 2.7e-16 59.2 0.0 1e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_6 PF00970.19 EAU86339.1 - 5.4e-06 26.4 0.0 0.0058 16.7 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Pyridox_oxidase PF01243.15 EAU86339.1 - 0.00014 21.8 0.0 0.014 15.3 0.0 3.8 4 1 0 4 4 4 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.16 EAU86339.1 - 0.0025 18.3 0.0 0.13 12.8 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EAU86339.1 - 0.0042 17.0 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PQ-loop PF04193.9 EAU86340.1 - 6.3e-24 83.2 3.5 9.8e-12 44.2 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF2142 PF09913.4 EAU86340.1 - 0.0055 15.4 5.4 0.007 15.0 3.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) DUF3767 PF12597.3 EAU86340.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF3270 PF11674.3 EAU86341.2 - 1 9.3 4.4 4.8 7.2 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF1113 PF06541.6 EAU86343.2 - 0.0045 16.7 4.1 0.0045 16.7 2.8 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1113) SieB PF14163.1 EAU86343.2 - 0.043 13.4 4.1 1.4 8.4 0.6 2.4 2 0 0 2 2 2 0 Superinfection exclusion protein B DUF3043 PF11241.3 EAU86343.2 - 0.092 12.3 0.2 0.092 12.3 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) Orbi_NS3 PF01616.11 EAU86343.2 - 0.15 11.0 2.4 2.1 7.2 1.0 2.3 2 0 0 2 2 2 0 Orbivirus NS3 Abhydrolase_9_N PF15420.1 EAU86343.2 - 0.49 10.0 8.0 1.1 8.9 5.5 1.6 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2207 PF09972.4 EAU86343.2 - 0.89 8.0 3.1 0.29 9.6 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Hom_end PF05204.9 EAU86345.2 - 0.031 14.2 0.1 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Homing endonuclease Ecm29 PF13001.2 EAU86345.2 - 0.067 11.6 0.0 0.083 11.3 0.0 1.0 1 0 0 1 1 1 0 Proteasome stabiliser PRP1_N PF06424.7 EAU86347.2 - 1.5e-45 154.7 3.2 1.5e-45 154.7 2.2 2.7 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EAU86347.2 - 3.1e-24 83.2 30.8 0.026 15.1 0.4 13.5 6 4 7 13 13 13 7 Tetratricopeptide repeat TPR_16 PF13432.1 EAU86347.2 - 1.2e-17 64.0 21.3 0.00014 22.4 0.0 8.2 8 1 3 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 EAU86347.2 - 1.4e-12 47.7 15.5 0.016 15.5 0.1 8.5 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EAU86347.2 - 2.9e-06 27.3 3.4 5 7.8 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAU86347.2 - 4.3e-06 26.2 6.6 0.046 13.3 0.0 6.6 4 2 2 6 6 6 2 TPR repeat TPR_17 PF13431.1 EAU86347.2 - 0.0055 16.8 0.2 1.6e+02 2.9 0.0 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU86347.2 - 0.15 12.0 4.0 25 4.8 0.0 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 EAU86347.2 - 0.15 11.9 7.8 0.31 10.9 0.4 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EAU86349.1 - 0.2 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EAU86350.1 - 9.9e-13 48.3 0.6 4.5e-05 23.3 0.1 3.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family DUF4498 PF14926.1 EAU86350.1 - 0.13 11.3 0.1 29 3.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4498) GDA1_CD39 PF01150.12 EAU86353.2 - 8.7e-87 291.3 0.0 3e-86 289.6 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MFS_1 PF07690.11 EAU86356.2 - 0.056 12.1 15.9 1.5 7.4 11.0 2.3 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF1996 PF09362.5 EAU86359.2 - 2.8e-62 210.4 0.1 3.4e-62 210.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SH3_1 PF00018.23 EAU86360.1 - 2.2e-07 30.1 0.1 1.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EAU86360.1 - 8.9e-05 21.8 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EAU86360.1 - 0.00016 21.1 0.0 0.00034 20.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3328 PF11807.3 EAU86360.1 - 0.044 13.4 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) PAP2 PF01569.16 EAU86361.2 - 5.7e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily Polysacc_lyase PF14099.1 EAU86362.2 - 0.0016 18.1 0.0 0.0077 15.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide lyase Na_H_Exchanger PF00999.16 EAU86363.2 - 5.7e-46 156.7 21.5 7.8e-46 156.3 14.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EAU86363.2 - 3 7.8 5.6 25 4.9 0.4 2.5 2 0 0 2 2 2 0 YrhC-like protein Peptidase_M36 PF02128.10 EAU86365.2 - 1e-90 304.3 0.4 1.3e-90 303.9 0.3 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EAU86365.2 - 6.8e-05 22.2 0.7 0.00015 21.1 0.5 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Reprolysin_2 PF13574.1 EAU86365.2 - 0.034 14.1 0.0 0.085 12.9 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like PepSY PF03413.14 EAU86365.2 - 0.039 14.6 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2235 PF09994.4 EAU86367.2 - 1.5e-52 178.7 0.8 1.1e-50 172.5 0.6 2.1 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.6 EAU86367.2 - 0.0068 16.1 0.1 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EAU86367.2 - 0.011 15.2 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EAU86367.2 - 0.012 15.1 0.0 0.038 13.4 0.0 1.7 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAU86367.2 - 0.022 14.4 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU86367.2 - 0.099 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2235 PF09994.4 EAU86368.1 - 0.0042 16.5 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.4 EAU86369.2 - 2.1e-79 266.7 0.1 2.9e-79 266.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) F-box-like PF12937.2 EAU86370.2 - 2.4e-07 30.3 2.0 4.9e-07 29.3 1.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86370.2 - 1e-05 25.0 3.4 2.5e-05 23.7 2.4 1.8 1 0 0 1 1 1 1 F-box domain Slx4 PF09494.5 EAU86370.2 - 0.071 12.8 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Slx4 endonuclease PhnG PF06754.7 EAU86373.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Kinesin PF00225.18 EAU86378.2 - 5.1e-91 304.8 0.0 1.4e-50 171.8 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain DNA_pol_B PF00136.16 EAU86380.1 - 0.088 11.5 8.7 0.1 11.3 6.1 1.0 1 0 0 1 1 1 0 DNA polymerase family B Octopine_DH PF02317.12 EAU86380.1 - 0.22 11.1 1.0 0.31 10.6 0.5 1.5 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF3734 PF12536.3 EAU86380.1 - 0.26 11.4 10.9 3.6 7.7 0.4 2.5 2 1 0 2 2 2 0 Patatin phospholipase Spc7 PF08317.6 EAU86380.1 - 0.44 9.1 15.1 0.52 8.9 10.1 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EAU86380.1 - 0.89 7.3 10.8 0.89 7.3 7.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EAU86380.1 - 1.1 9.1 24.0 0.21 11.3 13.4 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Bacillus_HBL PF05791.6 EAU86380.1 - 1.7 7.9 8.2 0.68 9.2 4.0 1.7 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EAU86380.1 - 2 8.0 17.2 2.9 7.4 11.9 1.4 1 1 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 EAU86380.1 - 3.2 5.9 25.5 3.8 5.6 17.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Sfi1_C PF10638.4 EAU86380.1 - 4.1 7.8 9.3 10 6.5 2.5 2.7 2 1 0 2 2 2 0 Spindle body associated protein C-terminus Syntaxin_2 PF14523.1 EAU86380.1 - 6.6 6.8 13.7 32 4.6 1.6 2.6 1 1 2 3 3 3 0 Syntaxin-like protein DUF4140 PF13600.1 EAU86380.1 - 7.1 7.1 12.9 1.6 9.2 4.7 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 EAU86380.1 - 7.5 5.4 17.7 12 4.6 12.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 EAU86380.1 - 8.4 5.3 19.9 5.6 5.9 12.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 ketoacyl-synt PF00109.21 EAU86383.2 - 3.3e-72 243.0 0.2 5.2e-72 242.3 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EAU86383.2 - 1.6e-49 168.9 0.0 2.6e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EAU86383.2 - 7.3e-35 119.3 1.4 1.4e-34 118.5 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EAU86383.2 - 2.1e-21 76.3 0.7 4.5e-21 75.2 0.5 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EAU86383.2 - 6.8e-11 42.8 0.0 8.2e-09 36.0 0.0 2.7 3 0 0 3 3 3 1 Thioesterase domain PP-binding PF00550.20 EAU86383.2 - 8.3e-09 35.5 0.0 1.9e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EAU86383.2 - 4.7e-06 26.6 0.7 0.00043 20.2 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU86383.2 - 8.4e-05 22.3 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EAU86383.2 - 0.0053 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain S1-like PF14444.1 EAU86383.2 - 0.043 13.5 0.2 0.46 10.2 0.0 2.7 3 0 0 3 3 3 0 S1-like adh_short PF00106.20 EAU86386.2 - 3.8e-18 65.9 0.0 5.8e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU86386.2 - 2.5e-09 37.0 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAU86386.2 - 0.014 15.1 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 EAU86387.2 - 4.9e-18 65.6 0.0 6.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU86387.2 - 8.3e-07 28.8 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAU86387.2 - 0.036 13.8 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_61 PF03443.9 EAU86388.2 - 3.2e-44 151.3 0.0 4.1e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EAU86389.1 - 6.6e-44 150.3 0.0 8.1e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 tRNA_bind PF01588.15 EAU86389.1 - 0.087 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative tRNA binding domain GST_C_2 PF13410.1 EAU86390.2 - 6.9e-05 22.6 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU86390.2 - 0.00079 19.3 0.4 0.0027 17.6 0.3 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU86390.2 - 0.016 15.6 0.1 0.022 15.2 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Clathrin-link PF09268.5 EAU86390.2 - 0.035 13.1 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Clathrin, heavy-chain linker SH3BP5 PF05276.9 EAU86390.2 - 0.1 11.9 0.2 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) SH3_1 PF00018.23 EAU86392.1 - 7.8e-12 44.4 0.1 1.2e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAU86392.1 - 8.1e-11 41.2 0.0 1.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EAU86392.1 - 5.7e-10 38.6 0.0 9.7e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMEMspv1-c74-12 PF11044.3 EAU86392.1 - 4.9 6.7 5.8 0.62 9.6 0.2 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DAO PF01266.19 EAU86393.2 - 4.1e-48 164.1 0.0 6e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAU86393.2 - 1.1e-07 31.0 2.9 9.2e-07 28.0 2.0 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EAU86393.2 - 5.3e-06 25.7 0.6 8.6e-06 25.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU86393.2 - 0.00055 18.9 0.4 0.5 9.2 0.8 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EAU86393.2 - 0.0012 18.8 0.1 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU86393.2 - 0.0069 16.3 0.9 0.017 15.1 0.4 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAU86393.2 - 0.015 13.7 1.4 0.023 13.1 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EAU86393.2 - 0.021 13.6 0.9 0.044 12.6 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EAU86393.2 - 0.03 13.9 0.2 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EAU86393.2 - 0.053 13.9 0.7 0.13 12.7 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU86393.2 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU86393.2 - 3.7 6.5 6.1 0.57 9.2 0.2 2.2 2 0 0 2 2 2 0 Thi4 family BNR PF02012.15 EAU86395.1 - 0.074 12.9 0.2 0.52 10.3 0.1 2.6 1 0 0 1 1 1 0 BNR/Asp-box repeat WW PF00397.21 EAU86397.1 - 5e-22 77.4 29.9 7.3e-05 22.5 0.1 6.8 6 0 0 6 6 6 6 WW domain RRM_6 PF14259.1 EAU86400.2 - 1e-10 41.4 0.4 3.6e-08 33.2 0.2 3.6 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU86400.2 - 8.8e-10 38.0 1.2 0.00026 20.5 0.0 4.4 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU86400.2 - 4.2e-05 23.3 0.1 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 EAU86401.2 - 3.1e-21 75.5 8.0 2.8e-20 72.3 0.2 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAU86401.2 - 1.6e-17 63.3 24.1 1.1e-13 50.6 7.9 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Pantoate_transf PF02548.10 EAU86404.1 - 6.6e-105 349.9 0.0 7.9e-105 349.6 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EAU86404.1 - 2.7e-07 30.0 0.1 4.9e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Orbi_VP5 PF00901.12 EAU86404.1 - 0.16 10.1 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ribonuc_L-PSP PF01042.16 EAU86405.2 - 9.6e-20 70.5 0.0 1.2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP F-box-like PF12937.2 EAU86408.2 - 1.4e-07 31.1 3.2 4.3e-07 29.5 2.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86408.2 - 1.6e-07 30.7 6.2 4.3e-07 29.4 4.3 1.8 1 0 0 1 1 1 1 F-box domain NACHT PF05729.7 EAU86409.2 - 1.4e-08 34.6 0.0 9.9e-08 31.8 0.0 2.5 2 1 1 3 3 3 1 NACHT domain AAA_16 PF13191.1 EAU86409.2 - 3.7e-05 23.8 0.4 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU86409.2 - 5.2e-05 23.3 0.1 0.00031 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAU86409.2 - 0.0086 15.7 0.0 0.025 14.2 0.0 1.8 1 0 0 1 1 1 1 Archaeal ATPase AAA_30 PF13604.1 EAU86409.2 - 0.014 14.9 0.3 0.027 14.0 0.2 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EAU86409.2 - 0.045 13.3 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EAU86409.2 - 0.05 12.4 0.0 0.25 10.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 EAU86409.2 - 0.081 11.8 0.1 0.17 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SE PF00437.15 EAU86409.2 - 0.084 11.7 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EAU86409.2 - 0.099 12.3 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EAU86409.2 - 0.11 12.7 0.4 0.92 9.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EAU86409.2 - 0.42 10.0 2.1 0.33 10.3 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EAU86409.2 - 3.1 8.0 5.8 25 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain Peptidase_M43 PF05572.8 EAU86410.2 - 3e-17 62.6 0.0 4.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU86410.2 - 0.00038 20.4 0.1 0.00062 19.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU86410.2 - 0.00094 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU86410.2 - 0.0012 18.8 1.5 0.0017 18.4 0.9 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAU86410.2 - 0.012 16.1 0.2 0.02 15.4 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EAU86410.2 - 0.045 12.6 1.0 0.07 11.9 0.7 1.2 1 0 0 1 1 1 0 Peptidase M66 RTA1 PF04479.8 EAU86411.2 - 5.8e-43 146.9 5.3 5.8e-43 146.9 3.7 1.5 1 1 0 1 1 1 1 RTA1 like protein Abhydrolase_9_N PF15420.1 EAU86411.2 - 0.16 11.6 4.8 5.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus bZIP_1 PF00170.16 EAU86412.1 - 1.4e-09 37.7 6.6 1.4e-09 37.7 4.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EAU86412.1 - 4.8e-06 26.2 8.7 4.8e-06 26.2 6.0 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EAU86412.1 - 0.79 10.0 10.2 0.58 10.4 5.8 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor p450 PF00067.17 EAU86414.2 - 1.3e-49 169.0 1.7 1.4e-26 93.1 0.1 2.0 1 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EAU86415.2 - 2.3e-63 214.3 0.0 3.2e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LHC PF00556.15 EAU86415.2 - 0.18 11.6 2.1 0.52 10.2 1.4 1.8 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit PspC PF04024.7 EAU86416.2 - 3.6 7.1 6.6 0.41 10.1 0.1 2.7 3 0 0 3 3 3 0 PspC domain SMC_N PF02463.14 EAU86418.1 - 1.7e-16 60.1 32.1 5.9e-16 58.3 20.4 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EAU86418.1 - 2.3e-14 54.2 17.1 2.3e-14 54.2 11.8 5.9 2 2 2 4 4 2 1 AAA domain GAS PF13851.1 EAU86418.1 - 3.1e-05 23.2 95.8 0.0011 18.1 12.1 5.8 2 2 1 4 4 4 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EAU86418.1 - 8.5e-05 21.3 76.7 0.013 14.1 11.2 4.4 3 1 1 4 4 4 3 Spc7 kinetochore protein MscS_porin PF12795.2 EAU86418.1 - 0.0002 20.7 4.5 0.0002 20.7 3.1 5.5 3 2 1 4 4 4 3 Mechanosensitive ion channel porin domain AAA_29 PF13555.1 EAU86418.1 - 0.00032 20.1 0.3 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_27 PF13514.1 EAU86418.1 - 0.00054 17.7 25.8 0.00054 17.7 17.9 2.8 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.1 EAU86418.1 - 0.001 17.6 81.2 0.0068 14.9 15.7 5.4 3 2 2 5 5 5 3 AAA domain AAA_15 PF13175.1 EAU86418.1 - 0.0011 18.0 14.8 0.0011 18.0 10.2 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.1 EAU86418.1 - 0.0019 18.2 6.3 0.0051 16.8 0.1 3.6 4 1 0 4 4 4 1 AAA domain ATG16 PF08614.6 EAU86418.1 - 0.0047 16.7 19.2 0.0047 16.7 13.3 5.8 2 2 3 5 5 3 1 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EAU86418.1 - 0.015 14.4 13.0 1.3 8.0 1.3 4.2 3 1 2 5 5 5 0 Reovirus sigma C capsid protein SbcCD_C PF13558.1 EAU86418.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Filament PF00038.16 EAU86418.1 - 4.8 6.5 84.7 0.81 9.1 9.6 4.2 2 2 1 3 3 3 0 Intermediate filament protein Cellulase PF00150.13 EAU86419.2 - 2.3e-11 43.4 0.0 3.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) OppC_N PF12911.2 EAU86419.2 - 0.0015 17.8 0.7 0.072 12.4 0.1 2.8 2 0 0 2 2 2 1 N-terminal TM domain of oligopeptide transport permease C DUF515 PF04415.7 EAU86419.2 - 0.009 14.2 0.3 0.013 13.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF515) Syndecan PF01034.15 EAU86419.2 - 0.13 11.9 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain NACHT PF05729.7 EAU86422.2 - 7.2e-08 32.2 0.0 3.2e-07 30.1 0.0 2.1 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAU86422.2 - 1.4e-05 25.1 0.0 4.5e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU86422.2 - 0.00053 20.1 0.0 0.0047 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU86422.2 - 0.0054 17.5 2.3 0.028 15.2 0.2 2.9 3 1 0 3 3 2 1 AAA domain DUF2075 PF09848.4 EAU86422.2 - 0.0073 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Syntaxin_2 PF14523.1 EAU86422.2 - 0.027 14.4 0.3 0.07 13.1 0.0 1.8 2 0 0 2 2 2 0 Syntaxin-like protein AAA_30 PF13604.1 EAU86422.2 - 0.037 13.5 0.1 0.072 12.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAU86422.2 - 0.073 12.7 0.0 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EAU86422.2 - 0.078 13.2 0.2 0.23 11.7 0.1 2.0 2 1 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EAU86422.2 - 0.084 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EAU86422.2 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 EAU86422.2 - 0.13 12.0 0.1 0.45 10.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain GST_N_3 PF13417.1 EAU86423.1 - 1.2e-12 47.8 0.0 2.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU86423.1 - 1.4e-09 37.8 0.0 2.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU86423.1 - 0.00047 19.9 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU86423.1 - 0.00067 20.0 0.1 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU86423.1 - 0.0045 16.9 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GMC_oxred_N PF00732.14 EAU86424.1 - 5.8e-68 229.1 0.0 7.3e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU86424.1 - 5.7e-37 127.2 0.0 1.8e-36 125.5 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EAU86424.1 - 0.0023 16.9 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EAU86424.1 - 0.0029 17.5 0.0 0.0071 16.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU86424.1 - 0.0058 16.6 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU86424.1 - 0.0085 14.9 0.0 0.025 13.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EAU86424.1 - 0.021 14.8 0.0 3.1 7.8 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU86424.1 - 0.042 12.7 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EAU86424.1 - 0.048 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Init_tRNA_PT PF04179.7 EAU86424.1 - 0.13 11.0 0.2 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase NACHT PF05729.7 EAU86425.2 - 4.9e-08 32.8 0.0 9.3e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU86425.2 - 0.0039 17.2 0.3 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EAU86425.2 - 0.0069 15.4 0.1 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 EAU86425.2 - 0.0099 14.7 0.0 0.074 11.8 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 EAU86425.2 - 0.02 14.4 0.1 0.058 12.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EAU86425.2 - 0.042 13.3 1.2 0.37 10.3 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EAU86425.2 - 0.08 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase GAT PF03127.9 EAU86425.2 - 0.081 12.9 0.2 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 GAT domain T2SF PF00482.18 EAU86425.2 - 0.09 12.6 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F UPF0079 PF02367.12 EAU86425.2 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 adh_short PF00106.20 EAU86426.2 - 5.7e-21 75.1 0.0 1e-20 74.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU86426.2 - 2.7e-09 36.9 0.0 4.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU86426.2 - 1.1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EAU86426.2 - 1.1e-05 24.9 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU86426.2 - 3.3e-05 23.9 0.1 4.8e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EAU86426.2 - 0.00061 19.8 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EAU86426.2 - 0.035 13.0 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EAU86426.2 - 0.042 12.9 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 EAU86426.2 - 0.063 12.2 0.1 0.091 11.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase LacI PF00356.16 EAU86426.2 - 0.075 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Pkinase PF00069.20 EAU86427.1 - 2.8e-69 233.1 0.0 3.9e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86427.1 - 1.1e-41 142.6 0.0 1.5e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU86427.1 - 1.9e-07 30.3 0.0 1.1e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAU86427.1 - 0.0042 16.8 0.5 0.62 9.7 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EAU86427.1 - 0.084 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.4 EAU86427.1 - 3.2 5.9 9.9 3.7 5.7 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein LPP20 PF02169.11 EAU86427.1 - 7.6 6.7 10.1 0.47 10.5 1.4 2.6 3 0 0 3 3 3 0 LPP20 lipoprotein Mob1_phocein PF03637.12 EAU86429.2 - 2.8e-64 216.0 0.3 3.8e-64 215.5 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Pex14_N PF04695.8 EAU86429.2 - 3.6 7.6 6.4 6.9 6.7 4.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_12 PF13424.1 EAU86431.1 - 1.1e-06 28.4 0.0 0.05 13.5 0.0 3.2 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU86431.1 - 7e-05 22.2 0.2 0.45 10.2 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU86431.1 - 7.4e-05 22.3 0.0 0.45 10.2 0.0 3.1 1 1 2 3 3 3 2 TPR repeat TPR_10 PF13374.1 EAU86431.1 - 7.7e-05 22.4 0.1 1 9.4 0.3 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU86431.1 - 0.004 16.9 0.2 1.1 9.3 0.0 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF4246 PF14033.1 EAU86432.1 - 2.9e-174 580.4 0.0 4.4e-174 579.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EAU86432.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase EBV-NA3 PF05009.7 EAU86432.1 - 0.2 10.9 1.0 0.3 10.2 0.7 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Glyco_hydro_28 PF00295.12 EAU86434.2 - 3.3e-38 131.4 0.1 1.4e-37 129.4 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EAU86434.2 - 0.15 11.8 5.4 0.085 12.6 0.9 2.3 1 1 1 2 2 2 0 Right handed beta helix region Pro_isomerase PF00160.16 EAU86435.1 - 1.6e-48 164.8 0.1 4.4e-48 163.3 0.1 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EAU86435.1 - 2.8e-10 39.6 0.5 2.8e-05 23.7 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Cutinase PF01083.17 EAU86436.1 - 2e-45 154.7 0.1 2.3e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EAU86436.1 - 3.8e-05 23.2 0.1 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EAU86436.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EAU86436.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAU86436.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase F-box-like PF12937.2 EAU86437.2 - 1e-10 41.1 0.2 3.3e-10 39.5 0.1 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86437.2 - 6.2e-05 22.5 0.4 0.00033 20.2 0.3 2.3 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EAU86437.2 - 0.24 11.0 3.7 1.1e+02 2.6 0.4 5.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) tRNA-synt_His PF13393.1 EAU86438.2 - 0.0083 15.2 0.1 0.019 14.0 0.0 1.5 1 1 0 1 1 1 1 Histidyl-tRNA synthetase F-box-like_2 PF13013.1 EAU86438.2 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain NAD_binding_10 PF13460.1 EAU86439.1 - 1.2e-13 51.4 0.0 4.8e-13 49.5 0.0 2.0 2 2 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EAU86439.1 - 0.038 13.8 0.2 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.16 EAU86439.1 - 0.066 12.6 0.2 1.2 8.4 0.1 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EAU86439.1 - 0.092 11.9 0.0 0.49 9.5 0.0 2.1 1 1 0 1 1 1 0 NmrA-like family NDK PF00334.14 EAU86440.1 - 2.8e-17 62.7 0.0 4.9e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4246 PF14033.1 EAU86441.2 - 4e-175 583.2 0.0 5.4e-175 582.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EAU86441.2 - 0.0049 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EAU86441.2 - 0.078 13.5 0.0 0.26 11.8 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 EAU86442.2 - 1.5e-65 217.5 19.6 3.5e-12 46.5 1.3 8.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU86442.2 - 5.7e-60 198.7 17.5 3e-09 37.1 0.0 11.1 4 3 9 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.25 EAU86442.2 - 5.2e-59 193.2 23.9 1.3e-05 24.7 0.7 12.9 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.1 EAU86442.2 - 5.4e-43 144.0 28.2 4.1e-08 33.2 0.1 9.2 4 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU86442.2 - 2.1e-38 126.4 11.4 0.0014 18.6 0.0 13.3 13 1 0 13 13 13 10 Ankyrin repeat AAA_22 PF13401.1 EAU86442.2 - 3.4e-07 30.4 0.0 1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAU86442.2 - 2.7e-05 23.9 0.1 5.6e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU86442.2 - 0.0011 19.0 0.6 0.0039 17.2 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain Ribosomal_S11 PF00411.14 EAU86442.2 - 0.0013 18.8 0.6 14 5.8 0.0 5.2 5 1 1 6 6 6 0 Ribosomal protein S11 NB-ARC PF00931.17 EAU86442.2 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Phosphoprotein PF00922.12 EAU86442.2 - 0.0017 17.6 0.1 33 3.5 0.0 4.5 4 1 1 5 5 5 0 Vesiculovirus phosphoprotein COX2-transmemb PF09125.5 EAU86442.2 - 0.028 13.9 0.2 88 2.7 0.0 4.0 4 0 0 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane SH3_2 PF07653.12 EAU86442.2 - 0.096 12.1 0.1 52 3.4 0.0 3.6 2 1 1 3 3 3 0 Variant SH3 domain DUF4246 PF14033.1 EAU86443.2 - 4.8e-164 546.6 0.0 8.2e-164 545.9 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EAU86443.2 - 0.0037 17.5 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase F-box-like PF12937.2 EAU86444.2 - 1.9e-08 33.8 0.7 3.9e-08 32.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU86444.2 - 0.0004 19.9 0.0 0.38 10.4 0.0 3.7 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF4315 PF14193.1 EAU86444.2 - 0.057 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Prefoldin_2 PF01920.15 EAU86444.2 - 0.089 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit DUF3847 PF12958.2 EAU86444.2 - 0.15 11.8 0.1 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) CDC37_N PF03234.9 EAU86445.1 - 3.9e-42 144.5 10.0 9.5e-42 143.3 6.9 1.7 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EAU86445.1 - 6.8e-39 133.1 2.3 1.1e-38 132.4 0.0 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EAU86445.1 - 6e-19 67.7 0.0 6e-19 67.7 0.0 2.9 2 1 0 2 2 2 1 Cdc37 C terminal domain Bd3614_N PF14442.1 EAU86445.1 - 0.012 15.5 0.7 0.03 14.3 0.5 1.6 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Orbi_VP5 PF00901.12 EAU86445.1 - 0.21 9.7 4.5 0.4 8.8 3.1 1.4 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 PTPlike_phytase PF14566.1 EAU86445.1 - 0.42 10.6 5.6 1.3 9.0 3.4 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate AF0941-like PF14591.1 EAU86445.1 - 1.1 9.2 11.2 0.27 11.2 3.2 3.0 3 0 0 3 3 3 0 AF0941-like Cu_bind_like PF02298.12 EAU86447.1 - 0.002 17.8 0.1 0.013 15.3 0.1 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain DUF883 PF05957.8 EAU86447.1 - 0.18 12.1 1.5 0.36 11.2 1.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.2 EAU86449.2 - 3.1e-08 33.2 0.7 1.7e-07 30.8 0.1 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAU86451.1 - 0.071 12.7 0.5 28 4.4 0.0 3.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Mob1_phocein PF03637.12 EAU86452.1 - 2.4e-60 203.1 0.2 3e-60 202.8 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF668 PF05003.7 EAU86452.1 - 0.16 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF668) zf-RING_2 PF13639.1 EAU86453.1 - 7.1e-05 22.5 0.2 0.00014 21.6 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain Sporozoite_P67 PF05642.6 EAU86453.1 - 0.92 7.2 20.6 3.8 5.2 14.3 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 EAU86453.1 - 1.2 8.9 25.3 3.4 7.4 2.4 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DEAD PF00270.24 EAU86454.2 - 2.5e-09 36.8 0.0 0.00013 21.5 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU86454.2 - 0.00025 20.8 0.0 0.0007 19.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU86454.2 - 0.022 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SPX PF03105.14 EAU86456.1 - 0.0074 16.1 1.2 0.0082 15.9 0.8 1.1 1 0 0 1 1 1 1 SPX domain Syntaxin-6_N PF09177.6 EAU86456.1 - 0.025 14.9 3.5 0.047 14.1 2.3 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal WXG100 PF06013.7 EAU86456.1 - 0.11 12.4 1.2 0.28 11.1 0.2 2.1 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Fic_N PF13784.1 EAU86460.2 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Fic/DOC family N-terminal F-box-like PF12937.2 EAU86462.1 - 0.00048 19.8 2.0 0.00082 19.0 0.2 2.4 3 0 0 3 3 3 1 F-box-like Peptidase_M36 PF02128.10 EAU86463.1 - 1.1e-113 379.9 7.9 1.3e-113 379.6 5.5 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) PepSY PF03413.14 EAU86463.1 - 0.0018 18.8 0.4 0.0076 16.8 0.2 2.2 2 0 0 2 2 2 1 Peptidase propeptide and YPEB domain FTP PF07504.8 EAU86463.1 - 0.0056 16.1 0.2 0.013 14.9 0.1 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EAU86463.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Methyltransf_31 PF13847.1 EAU86466.2 - 7.3e-18 64.6 0.0 9.5e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU86466.2 - 4.9e-15 55.6 0.0 4.9e-15 55.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU86466.2 - 1.6e-13 50.9 0.0 3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU86466.2 - 8.8e-13 48.5 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU86466.2 - 1.1e-11 45.2 0.0 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU86466.2 - 1.5e-10 41.1 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU86466.2 - 8.9e-10 38.8 0.1 1.8e-09 37.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EAU86466.2 - 1.4e-08 34.3 0.0 2.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EAU86466.2 - 1.2e-06 27.8 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EAU86466.2 - 9.5e-06 24.9 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 EAU86466.2 - 0.0008 18.8 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Cons_hypoth95 PF03602.10 EAU86466.2 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 NodS PF05401.6 EAU86466.2 - 0.0028 17.0 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 EAU86466.2 - 0.0059 15.7 0.0 0.0072 15.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EAU86466.2 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EAU86466.2 - 0.017 15.9 0.1 0.054 14.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EAU86466.2 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.15 EAU86466.2 - 0.03 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 EAU86466.2 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.1 EAU86466.2 - 0.052 13.2 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EAU86466.2 - 0.078 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DREV PF05219.7 EAU86466.2 - 0.098 11.5 0.0 0.18 10.6 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase DLH PF01738.13 EAU86468.1 - 7e-19 67.9 0.5 8.5e-19 67.7 0.3 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU86468.1 - 7.7e-08 32.2 0.1 1.2e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU86468.1 - 0.00035 20.5 0.1 0.0022 17.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU86468.1 - 0.062 12.5 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family GFO_IDH_MocA PF01408.17 EAU86469.1 - 1.4e-10 41.6 0.1 2.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAU86469.1 - 0.086 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Methyltransf_25 PF13649.1 EAU86469.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DLH PF01738.13 EAU86474.1 - 3.3e-23 82.1 0.3 4e-23 81.8 0.2 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU86474.1 - 5.3e-09 35.9 0.1 8.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU86474.1 - 6.8e-07 29.4 0.2 0.0022 17.8 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU86474.1 - 0.0082 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family GFO_IDH_MocA PF01408.17 EAU86475.1 - 9.3e-11 42.3 0.0 1.5e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cerato-platanin PF07249.7 EAU86476.1 - 8.2e-14 51.6 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 EAU86477.1 - 8.1e-08 32.2 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Cerato-platanin TctB PF07331.6 EAU86478.1 - 1.3 8.6 9.0 1.4 8.5 4.6 2.1 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family GFO_IDH_MocA PF01408.17 EAU86479.1 - 2.4e-05 24.8 0.0 0.0003 21.2 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAU86479.1 - 0.08 12.7 0.0 0.26 11.0 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain EphA2_TM PF14575.1 EAU86480.1 - 0.0039 17.5 0.0 0.0097 16.2 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.15 EAU86480.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Rick_17kDa_Anti PF05433.10 EAU86480.1 - 0.023 14.3 3.3 0.062 12.9 2.3 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EAU86480.1 - 0.035 13.7 3.2 0.083 12.5 2.2 1.6 1 0 0 1 1 1 0 Glycine zipper YajC PF02699.10 EAU86480.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit TFIIA PF03153.8 EAU86480.1 - 1.2 8.9 7.6 1.6 8.5 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAGE_N PF12440.3 EAU86488.2 - 0.022 15.0 5.4 0.026 14.7 3.7 1.1 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal SSP160 PF06933.6 EAU86488.2 - 0.051 11.5 1.3 0.057 11.4 0.9 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Paxillin PF03535.8 EAU86489.2 - 0.019 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Paxillin family DUF2408 PF10303.4 EAU86495.2 - 0.035 14.2 1.0 0.17 12.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Tet_JBP PF12851.2 EAU86498.2 - 8.7e-14 51.1 0.0 1.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.2 EAU86499.1 - 1.7e-16 60.0 0.0 2.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HMG_box_2 PF09011.5 EAU86505.2 - 0.0028 17.9 0.1 0.012 15.9 0.1 2.1 1 0 0 1 1 1 1 HMG-box domain Pkinase PF00069.20 EAU86510.2 - 7e-19 67.9 0.0 1.4e-18 66.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86510.2 - 1.9e-07 30.4 0.0 9.1e-07 28.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase F-box PF00646.28 EAU86510.2 - 0.0099 15.5 0.3 0.035 13.7 0.2 2.0 1 0 0 1 1 1 1 F-box domain PIF1 PF05970.9 EAU86511.2 - 0.0018 17.3 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 EAU86511.2 - 0.011 15.7 0.0 0.098 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EAU86511.2 - 0.028 13.9 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAU86511.2 - 0.044 12.6 0.1 0.098 11.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Toxin_19 PF08088.7 EAU86516.2 - 0.51 10.2 3.1 0.89 9.5 2.2 1.4 1 0 0 1 1 1 0 Conotoxin I-superfamily F-box-like PF12937.2 EAU86517.1 - 6.1e-07 29.0 2.2 1.7e-06 27.6 1.5 1.8 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU86518.1 - 2.7e-06 26.9 1.3 3.4e-06 26.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU86518.1 - 0.00025 20.5 0.1 0.00025 20.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EAU86518.1 - 0.11 12.1 0.2 0.11 12.1 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAU86518.1 - 0.21 11.9 1.6 17 6.1 0.3 4.4 4 0 0 4 4 4 0 Leucine rich repeat CBM_1 PF00734.13 EAU86519.2 - 3e-05 23.5 4.1 3e-05 23.5 2.8 1.5 2 0 0 2 2 2 1 Fungal cellulose binding domain PIF1 PF05970.9 EAU86521.2 - 3.8e-112 374.8 0.0 5.3e-112 374.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAU86521.2 - 4e-68 228.7 0.0 8.5e-68 227.7 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU86521.2 - 7.9e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EAU86521.2 - 1.9e-05 24.7 0.0 4.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAU86521.2 - 0.0027 15.5 0.0 0.0039 15.0 0.0 1.1 1 0 0 1 1 1 1 Helicase Terminase_GpA PF05876.7 EAU86521.2 - 0.0031 15.9 0.3 0.005 15.2 0.2 1.2 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) AAA_16 PF13191.1 EAU86521.2 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF3296 PF11726.3 EAU86521.2 - 0.0054 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) AAA_19 PF13245.1 EAU86521.2 - 0.013 15.2 1.1 0.041 13.6 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain Torsin PF06309.6 EAU86521.2 - 0.17 11.7 0.2 0.83 9.5 0.0 2.2 3 0 0 3 3 2 0 Torsin ResIII PF04851.10 EAU86521.2 - 0.23 11.2 0.0 0.49 10.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EAU86521.2 - 0.9 8.3 0.0 1.6 7.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain F-box-like PF12937.2 EAU86522.2 - 0.012 15.3 0.9 0.086 12.5 0.1 2.8 3 0 0 3 3 3 0 F-box-like F-box PF00646.28 EAU86522.2 - 0.021 14.4 0.1 0.021 14.4 0.1 2.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EAU86523.2 - 2.6e-05 23.8 0.3 5.4e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like Ribosomal_S13_N PF08069.7 EAU86525.2 - 0.014 15.2 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Yip1 PF04893.12 EAU86525.2 - 0.18 11.2 2.5 0.25 10.8 1.7 1.2 1 1 0 1 1 1 0 Yip1 domain PX PF00787.19 EAU86527.1 - 2.1e-14 53.2 0.0 4.7e-14 52.1 0.0 1.5 2 0 0 2 2 2 1 PX domain F-box PF00646.28 EAU86530.2 - 0.26 11.0 0.0 0.26 11.0 0.0 2.9 4 0 0 4 4 4 0 F-box domain DUF2945 PF11160.3 EAU86531.1 - 8.9e-21 73.4 0.0 1e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) CBM_1 PF00734.13 EAU86532.2 - 1.4e-07 31.0 3.8 1.4e-07 31.0 2.6 5.2 5 1 0 5 5 5 1 Fungal cellulose binding domain F-box-like PF12937.2 EAU86533.2 - 6.4e-08 32.1 5.4 6.9e-05 22.4 0.3 3.6 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 EAU86533.2 - 0.0023 17.5 0.8 0.019 14.5 0.4 2.8 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EAU86533.2 - 0.91 9.3 6.0 4.7 7.0 0.0 4.5 4 1 0 4 4 4 0 Leucine rich repeat DUF3208 PF11482.3 EAU86537.2 - 0.053 13.6 0.2 3.4 7.8 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3208) F-box-like PF12937.2 EAU86538.2 - 1.1e-07 31.4 0.0 4e-07 29.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU86538.2 - 0.19 11.3 2.8 15 5.3 0.3 3.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EAU86539.2 - 8.9e-07 28.5 2.3 3.6e-06 26.5 0.0 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EAU86539.2 - 0.011 15.3 0.2 0.062 12.9 0.1 2.2 1 1 0 1 1 1 0 F-box domain CBM_1 PF00734.13 EAU86540.2 - 1.6e-05 24.4 1.7 1.6e-05 24.4 1.2 3.2 4 1 0 4 4 4 1 Fungal cellulose binding domain Mpv17_PMP22 PF04117.7 EAU86541.1 - 8.6e-22 76.5 0.2 1.4e-21 75.9 0.2 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1129 PF06570.6 EAU86541.1 - 0.084 12.1 0.2 0.34 10.1 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Zn_clus PF00172.13 EAU86544.2 - 0.027 14.3 1.0 0.027 14.3 0.7 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 EAU86548.1 - 5.7e-28 97.0 0.0 7.4e-28 96.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EAU86548.1 - 1.2e-19 70.3 0.0 1.6e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin HMG14_17 PF01101.13 EAU86548.1 - 8.6e-07 29.5 16.3 1.9e-06 28.4 11.3 1.5 1 0 0 1 1 1 1 HMG14 and HMG17 AhpC-TSA_2 PF13911.1 EAU86548.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme IER PF05760.7 EAU86548.1 - 1.1 9.1 7.4 1.5 8.6 4.9 1.3 1 1 0 1 1 1 0 Immediate early response protein (IER) TT_ORF2 PF02957.10 EAU86548.1 - 1.1 9.9 4.2 1.8 9.2 2.9 1.4 1 0 0 1 1 1 0 TT viral ORF2 LRR_4 PF12799.2 EAU86549.2 - 1.8e-09 36.9 14.6 0.0079 15.8 2.5 5.8 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EAU86549.2 - 1.1e-08 34.2 19.7 1.2 9.4 0.5 8.2 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.28 EAU86549.2 - 2.3e-05 23.8 8.7 19 5.7 0.1 7.9 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.1 EAU86549.2 - 0.0013 18.4 17.0 0.38 10.5 3.7 5.1 4 1 0 4 4 4 2 Leucine rich repeat GAT PF03127.9 EAU86549.2 - 0.041 13.8 0.2 0.087 12.7 0.2 1.5 1 0 0 1 1 1 0 GAT domain LRR_7 PF13504.1 EAU86549.2 - 0.26 11.6 19.0 48 4.8 0.0 8.5 9 0 0 9 9 9 0 Leucine rich repeat GST_N_3 PF13417.1 EAU86550.2 - 5e-07 29.8 0.1 1.1e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU86550.2 - 3.8e-05 23.5 0.1 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU86550.2 - 4.1e-05 23.3 0.9 0.00013 21.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU86550.2 - 0.0015 19.0 0.0 0.0031 17.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU86550.2 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Transaldolase PF00923.14 EAU86551.1 - 6.3e-94 314.3 0.0 7.2e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Solute_trans_a PF03619.11 EAU86552.2 - 2.4e-99 332.0 8.4 2.9e-99 331.8 5.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Redoxin PF08534.5 EAU86553.2 - 2e-39 134.4 0.0 2.2e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EAU86553.2 - 5.4e-14 51.9 0.0 6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ribosomal_L7Ae PF01248.21 EAU86554.2 - 4.2e-22 77.4 1.0 6.9e-22 76.7 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RepB PF07506.6 EAU86554.2 - 0.089 12.6 1.6 2.9 7.7 0.1 2.5 2 0 0 2 2 2 0 RepB plasmid partitioning protein Pkinase PF00069.20 EAU86555.1 - 2.3e-14 53.1 0.0 3.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86555.1 - 2.3e-05 23.5 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU86555.1 - 0.0019 17.9 0.5 0.011 15.5 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF2169 PF09937.4 EAU86555.1 - 0.052 12.6 0.1 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Pex19 PF04614.7 EAU86564.1 - 8.5e-57 192.6 1.4 8.5e-57 192.6 1.0 1.7 2 0 0 2 2 2 1 Pex19 protein family TraC PF07820.7 EAU86564.1 - 0.4 10.9 2.3 3.5 7.8 0.1 2.5 2 0 0 2 2 2 0 TraC-like protein Ribosomal_60s PF00428.14 EAU86564.1 - 7.7 6.9 10.3 4.1 7.8 0.6 3.6 2 1 1 3 3 3 0 60s Acidic ribosomal protein GCR1_C PF12550.3 EAU86566.2 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes AA_permease PF00324.16 EAU86568.1 - 9.2e-136 452.9 32.9 1.1e-135 452.7 22.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAU86568.1 - 2.5e-35 121.8 36.0 3.3e-35 121.4 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease NUFIP1 PF10453.4 EAU86568.1 - 0.13 11.8 0.6 0.22 11.0 0.4 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) T_cell_tran_alt PF15128.1 EAU86568.1 - 0.81 9.1 3.8 0.33 10.4 0.1 2.3 2 0 0 2 2 2 0 T-cell leukemia translocation-altered DUF3413 PF11893.3 EAU86569.2 - 0.28 10.0 5.5 0.069 12.0 0.8 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF3413) Asp PF00026.18 EAU86572.1 - 4.1e-07 29.5 0.0 8.7e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease PIF1 PF05970.9 EAU86573.2 - 0.00031 19.8 0.0 0.0022 17.0 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EAU86573.2 - 0.096 12.2 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU86573.2 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EAU86573.2 - 0.25 10.8 1.1 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2681 PF10883.3 EAU86579.1 - 0.017 15.2 3.2 0.029 14.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Allexi_40kDa PF05549.6 EAU86579.1 - 0.034 13.4 2.4 0.042 13.1 1.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4315 PF14193.1 EAU86579.1 - 0.047 13.6 3.8 0.11 12.4 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DUF1635 PF07795.6 EAU86579.1 - 3.4 6.9 8.5 2 7.7 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) Asp PF00026.18 EAU86582.2 - 9.3e-07 28.3 2.0 2.2e-05 23.8 1.4 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.1 EAU86582.2 - 0.0077 16.0 0.0 0.058 13.2 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease DUF1092 PF06485.6 EAU86582.2 - 0.095 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Asp_protease_2 PF13650.1 EAU86582.2 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 2 0 0 2 2 2 0 Aspartyl protease Peptidase_M14 PF00246.19 EAU86583.2 - 3.1e-56 191.0 0.0 3.9e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase FAD_binding_4 PF01565.18 EAU86584.1 - 3.7e-18 65.3 1.1 5.7e-18 64.7 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Acetyltransf_2 PF00797.12 EAU86585.1 - 1.2e-27 97.0 0.0 6.7e-27 94.6 0.0 2.0 1 1 0 1 1 1 1 N-acetyltransferase p450 PF00067.17 EAU86586.2 - 1.3e-66 225.0 0.1 2.3e-66 224.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EAU86587.2 - 2.7e-42 144.7 41.2 2.7e-42 144.7 28.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU86587.2 - 7.4e-14 51.1 14.1 7.4e-14 51.1 9.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter YfmQ PF10787.4 EAU86587.2 - 0.059 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group FolB PF02152.13 EAU86588.2 - 3.1e-23 82.0 0.0 1.9e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase ATG13 PF10033.4 EAU86589.2 - 1.7e-26 93.1 0.0 2.4e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 Chorion_3 PF05387.6 EAU86594.1 - 4.4 6.6 6.9 4.7 6.5 4.8 1.0 1 0 0 1 1 1 0 Chorion family 3 Peptidase_S8 PF00082.17 EAU86596.2 - 4.6e-30 104.7 13.4 3.1e-28 98.7 8.1 2.7 1 1 1 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.11 EAU86596.2 - 1.8e-06 28.4 0.0 1.3e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase inhibitor I9 ETRAMP PF09716.5 EAU86596.2 - 0.037 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sugar_tr PF00083.19 EAU86601.1 - 2.8e-103 345.9 15.2 3.5e-103 345.6 10.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU86601.1 - 3.9e-20 71.8 28.8 1.4e-15 56.9 6.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAU86601.1 - 3.3e-05 22.4 20.1 3.6e-05 22.3 0.4 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EAU86601.1 - 0.00065 18.0 0.8 0.00065 18.0 0.6 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EAU86601.1 - 0.001 17.8 0.7 0.0028 16.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Phage_holin_2 PF04550.7 EAU86601.1 - 0.077 13.0 2.0 0.57 10.3 1.3 2.3 1 1 1 2 2 2 0 Phage holin family 2 Nucleoplasmin PF03066.10 EAU86602.2 - 0.01 15.3 1.3 0.014 14.9 0.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin ATG27 PF09451.5 EAU86602.2 - 0.03 13.5 0.1 0.038 13.2 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 CENP-B_dimeris PF09026.5 EAU86602.2 - 0.11 12.7 6.5 0.18 12.0 4.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EAU86602.2 - 0.2 11.2 2.1 0.27 10.8 1.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 EAU86602.2 - 2.1 8.1 4.3 0.91 9.3 1.5 1.5 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.7 EAU86602.2 - 2.6 5.8 4.4 3.1 5.6 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family RNase_P_p30 PF01876.11 EAU86606.2 - 1.3e-28 99.1 0.0 2.9e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 RNase P subunit p30 Acetyltransf_2 PF00797.12 EAU86607.2 - 3.8e-27 95.4 0.0 5.1e-24 85.1 0.0 2.6 2 1 0 2 2 2 2 N-acetyltransferase zf-CCCH PF00642.19 EAU86608.1 - 0.0048 16.5 0.6 0.0081 15.8 0.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DBR1 PF05011.8 EAU86610.2 - 6.4e-35 120.1 0.0 8.3e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EAU86610.2 - 0.00026 20.4 2.6 0.00036 19.9 1.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-MYND PF01753.13 EAU86612.2 - 9e-11 41.4 4.9 1.9e-10 40.4 3.4 1.6 1 0 0 1 1 1 1 MYND finger tRNA_NucTran2_2 PF13735.1 EAU86612.2 - 0.0039 17.0 0.2 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 tRNA nucleotidyltransferase domain 2 putative F-box-like PF12937.2 EAU86613.2 - 1.1e-06 28.2 0.0 3.7e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like HTH_31 PF13560.1 EAU86618.1 - 2e-09 37.5 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EAU86618.1 - 9.6e-09 34.9 0.0 1.1e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EAU86618.1 - 8.7e-05 22.5 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 EAU86618.1 - 0.00026 21.1 0.0 0.00031 20.8 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_AsnC-type PF13404.1 EAU86618.1 - 0.12 11.8 0.3 0.25 10.8 0.1 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.7 EAU86618.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Ribosomal_S11 PF00411.14 EAU86619.1 - 7.2e-41 138.8 0.6 9e-41 138.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Acyltransferase PF01553.16 EAU86620.2 - 8.2e-15 54.4 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-C3HC4_3 PF13920.1 EAU86621.2 - 3.5e-08 32.9 4.8 5.5e-08 32.3 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU86621.2 - 6.6e-08 32.1 5.3 1.1e-07 31.4 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EAU86621.2 - 2.9e-07 30.1 7.9 5.6e-07 29.2 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAU86621.2 - 6.1e-06 26.1 8.6 1e-05 25.4 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU86621.2 - 1.3e-05 24.8 1.5 2.8e-05 23.7 0.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EAU86621.2 - 4.3e-05 23.0 7.4 7.3e-05 22.3 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EAU86621.2 - 0.0079 15.9 1.0 0.014 15.1 0.7 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EAU86621.2 - 0.033 13.7 7.0 0.053 13.1 4.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EAU86621.2 - 0.11 12.3 8.1 0.26 11.1 5.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CorA PF01544.13 EAU86621.2 - 0.98 8.3 4.5 1.8 7.5 3.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Synaptobrevin PF00957.16 EAU86622.2 - 7.3e-29 99.2 0.2 9.9e-29 98.7 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EAU86622.2 - 1.9e-20 72.1 0.0 3.3e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec61_beta PF03911.11 EAU86624.1 - 6.8e-18 64.1 0.3 8.6e-18 63.8 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Pkinase PF00069.20 EAU86626.1 - 9e-06 25.0 0.0 1.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86626.1 - 0.0012 17.9 0.0 0.0029 16.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EAU86626.1 - 0.014 15.0 0.1 0.033 13.7 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase SET PF00856.23 EAU86628.2 - 3.9e-16 59.7 0.1 2.8e-10 40.7 0.0 2.5 2 1 0 2 2 2 2 SET domain TIM PF00121.13 EAU86629.1 - 3.6e-92 307.8 0.1 4e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Glyco_hydro_15 PF00723.16 EAU86629.1 - 0.065 11.7 0.0 0.069 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Beach PF02138.13 EAU86631.2 - 3.6e-101 338.1 0.0 8.3e-101 336.9 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 EAU86631.2 - 5.1e-09 36.5 0.0 1.3e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 EAU86631.2 - 2.7e-08 33.5 0.0 5.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EAU86631.2 - 1.4e-07 31.0 1.7 0.0014 18.4 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat UBA PF00627.26 EAU86631.2 - 0.11 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Mito_carr PF00153.22 EAU86632.2 - 7.1e-49 163.4 2.0 2e-18 65.8 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein EthD PF07110.6 EAU86633.1 - 0.016 16.1 0.3 0.076 13.9 0.1 2.2 2 1 0 2 2 2 0 EthD domain F-box-like PF12937.2 EAU86634.1 - 2.3e-10 40.0 0.6 7.8e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU86634.1 - 7.2e-05 22.3 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain Methyltransf_11 PF08241.7 EAU86635.2 - 4.5e-06 27.0 0.0 9.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU86635.2 - 0.00015 22.0 0.0 0.056 13.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EAU86635.2 - 0.0095 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU86635.2 - 0.037 14.4 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 EAU86638.1 - 2e-09 36.9 1.1 3.6e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU86638.1 - 0.0021 17.6 0.0 0.0054 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 EAU86639.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU86640.2 - 0.012 15.3 0.2 0.052 13.2 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EAU86640.2 - 0.046 12.8 0.1 0.074 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain Yip1 PF04893.12 EAU86642.2 - 0.0069 15.8 13.8 0.021 14.3 9.6 1.8 1 1 0 1 1 1 1 Yip1 domain Tetraspannin PF00335.15 EAU86642.2 - 0.35 10.1 10.7 1.6 7.9 6.0 2.0 2 0 0 2 2 2 0 Tetraspanin family Pil1 PF13805.1 EAU86643.2 - 3.7e-15 55.7 0.0 6.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 GAS PF13851.1 EAU86643.2 - 0.061 12.5 0.8 0.097 11.8 0.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding F-box-like PF12937.2 EAU86648.1 - 2.8e-06 26.9 0.0 7.8e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU86648.1 - 0.00011 21.7 0.3 0.00037 20.0 0.1 1.9 2 0 0 2 2 2 1 F-box domain ABC_sub_bind PF04392.7 EAU86648.1 - 0.059 12.3 0.1 0.8 8.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter substrate binding protein F-box-like PF12937.2 EAU86649.1 - 0.0067 16.1 1.1 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like Nucleoplasmin PF03066.10 EAU86649.1 - 0.011 15.2 5.4 0.02 14.4 3.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EAU86649.1 - 0.033 14.0 0.4 0.066 13.0 0.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 EAU86649.1 - 0.052 13.7 8.0 0.094 12.9 5.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF950 PF06106.6 EAU86649.1 - 0.062 13.3 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Staphylococcus protein of unknown function (DUF950) F-box PF00646.28 EAU86649.1 - 0.13 11.9 2.6 0.4 10.3 0.1 2.8 2 0 0 2 2 2 0 F-box domain Sigma70_ner PF04546.8 EAU86649.1 - 0.38 10.3 5.0 0.6 9.6 3.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EAU86649.1 - 1.1 7.9 15.1 1.6 7.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EAU86649.1 - 3.3 6.8 7.5 5.1 6.2 5.2 1.2 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.20 EAU86651.2 - 4.7e-41 140.6 0.0 6.3e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86651.2 - 3.5e-16 59.0 0.0 5.6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAU86651.2 - 0.006 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU86651.2 - 0.0084 15.8 0.1 0.029 14.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU86651.2 - 0.0086 15.0 0.0 3.1 6.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.15 EAU86651.2 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pyr_redox_dim PF02852.17 EAU86652.1 - 1e-39 134.9 0.8 2.1e-39 133.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EAU86652.1 - 6.4e-38 130.6 16.1 6.4e-36 124.1 11.1 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU86652.1 - 1.5e-20 73.3 8.8 2e-18 66.5 1.2 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAU86652.1 - 2.3e-12 46.5 4.3 6.2e-11 41.7 0.4 2.5 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 EAU86652.1 - 9e-12 44.7 0.2 9e-12 44.7 0.1 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAU86652.1 - 1.6e-09 38.1 1.4 0.00018 21.6 0.3 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU86652.1 - 1.9e-07 30.3 3.3 1.9e-07 30.3 2.3 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EAU86652.1 - 4.2e-07 29.9 7.5 0.00063 19.7 0.4 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EAU86652.1 - 3.3e-06 26.2 0.3 0.088 11.7 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EAU86652.1 - 9.9e-06 24.2 15.0 0.00022 19.8 1.2 3.9 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 EAU86652.1 - 1.5e-05 24.2 4.2 0.00031 19.9 0.1 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EAU86652.1 - 4.3e-05 22.5 18.8 0.01 14.7 1.3 3.6 2 2 2 4 4 4 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU86652.1 - 4.6e-05 22.6 10.8 0.013 14.6 0.5 3.9 3 1 0 4 4 4 2 FAD binding domain AlaDh_PNT_C PF01262.16 EAU86652.1 - 8e-05 22.2 5.4 0.035 13.6 0.2 3.3 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 EAU86652.1 - 0.0065 15.5 0.7 0.09 11.8 0.0 3.0 4 0 0 4 4 4 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.7 EAU86652.1 - 0.42 9.4 6.2 0.38 9.6 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EAU86652.1 - 1 9.6 4.0 11 6.2 1.1 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF4293 PF14126.1 EAU86654.1 - 0.74 9.7 6.0 0.65 9.9 2.6 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) ABC2_membrane_3 PF12698.2 EAU86654.1 - 1 8.2 7.2 0.75 8.7 4.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Pectate_lyase_3 PF12708.2 EAU86655.2 - 2.5e-84 282.9 10.4 5e-67 226.3 1.6 2.6 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EAU86655.2 - 1.6e-06 27.4 0.0 0.053 13.0 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EAU86655.2 - 0.044 13.5 6.2 0.17 11.6 4.2 2.1 1 1 0 1 1 1 0 Right handed beta helix region adh_short PF00106.20 EAU86656.2 - 1.9e-15 57.1 0.0 3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU86656.2 - 5.6e-11 42.6 0.0 7.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.14 EAU86657.2 - 1.3e-19 70.5 0.1 1.1e-18 67.4 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EAU86657.2 - 0.0014 18.6 0.2 0.0029 17.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAU86657.2 - 0.0036 17.1 0.1 0.0073 16.0 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EAU86657.2 - 0.13 11.1 0.1 0.61 8.9 0.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein ABC2_membrane_4 PF12730.2 EAU86658.2 - 0.019 14.1 0.1 0.019 14.1 0.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein PHO4 PF01384.15 EAU86659.2 - 5e-107 357.3 17.8 6.8e-107 356.8 12.4 1.2 1 0 0 1 1 1 1 Phosphate transporter family DUF4010 PF13194.1 EAU86660.2 - 0.012 14.9 1.9 0.026 13.8 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Ferric_reduct PF01794.14 EAU86660.2 - 0.025 14.6 0.4 0.16 12.0 0.0 2.3 2 1 0 2 2 2 0 Ferric reductase like transmembrane component Neurensin PF14927.1 EAU86660.2 - 0.061 12.7 3.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Neurensin TctB PF07331.6 EAU86660.2 - 0.21 11.2 6.0 0.4 10.3 4.1 1.5 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF3325 PF11804.3 EAU86660.2 - 0.43 10.5 4.4 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) SUR7 PF06687.7 EAU86660.2 - 3.3 7.2 6.2 6.7 6.2 1.0 2.0 2 0 0 2 2 2 0 SUR7/PalI family DUF805 PF05656.9 EAU86660.2 - 3.4 7.4 5.2 9.9 6.0 3.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4131 PF13567.1 EAU86660.2 - 10 5.5 6.8 1.7 8.0 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) adh_short PF00106.20 EAU86661.2 - 3.4e-15 56.3 0.0 4.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU86661.2 - 3.5e-08 33.4 0.0 6.5e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU86661.2 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 KR domain MutS_III PF05192.13 EAU86661.2 - 0.0054 16.5 0.1 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain III NAD_binding_10 PF13460.1 EAU86661.2 - 0.009 16.0 0.0 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Hemerythrin PF01814.18 EAU86662.1 - 6.7e-11 42.4 0.9 1e-10 41.9 0.6 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAND PF09110.6 EAU86662.1 - 0.16 12.4 2.0 0.2 12.0 0.5 1.8 2 0 0 2 2 2 0 HAND Hemerythrin PF01814.18 EAU86663.1 - 2.9e-11 43.6 2.1 4.8e-11 42.9 1.5 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain F-box-like PF12937.2 EAU86666.2 - 1.8e-05 24.3 0.0 7.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like V-SNARE_C PF12352.3 EAU86666.2 - 0.029 14.4 1.0 0.82 9.7 0.3 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus DUF2828 PF11443.3 EAU86666.2 - 0.073 11.2 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NfeD PF01957.13 EAU86671.2 - 7.1 6.7 7.6 18 5.4 3.6 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding FHA PF00498.21 EAU86673.2 - 1.9e-14 53.5 0.0 3.4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EAU86673.2 - 2e-08 33.9 14.7 2.9e-08 33.3 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAU86673.2 - 3.7e-05 23.7 3.9 6.9e-05 22.8 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EAU86673.2 - 0.001 18.8 3.9 0.0016 18.2 2.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EAU86673.2 - 0.0025 17.4 12.9 0.0041 16.7 8.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU86673.2 - 0.0028 17.2 15.0 0.0044 16.6 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU86673.2 - 0.083 12.9 16.4 0.13 12.2 11.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EAU86673.2 - 2 8.1 8.4 3.5 7.4 5.8 1.3 1 0 0 1 1 1 0 PHD-finger ABC_membrane PF00664.18 EAU86674.2 - 4.4e-56 190.3 33.9 2e-28 99.5 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAU86674.2 - 3.7e-54 182.7 0.1 2e-28 99.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAU86674.2 - 1.5e-08 34.1 6.4 0.0028 16.8 0.1 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU86674.2 - 1.6e-08 34.8 0.1 1 9.2 0.0 4.4 3 1 0 4 4 4 3 AAA domain MMR_HSR1 PF01926.18 EAU86674.2 - 1.3e-07 31.5 0.1 0.01 15.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EAU86674.2 - 1.5e-06 27.6 0.1 0.028 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EAU86674.2 - 1.6e-06 28.6 0.2 0.023 15.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EAU86674.2 - 2.5e-06 27.6 0.9 0.0074 16.2 0.3 2.9 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 EAU86674.2 - 8.5e-06 25.6 0.2 0.027 14.2 0.0 2.8 2 0 0 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 EAU86674.2 - 1.7e-05 24.4 0.1 0.25 10.7 0.0 2.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_23 PF13476.1 EAU86674.2 - 0.00017 21.9 1.0 0.64 10.3 0.0 3.2 2 1 1 3 3 3 2 AAA domain DUF258 PF03193.11 EAU86674.2 - 0.00027 20.1 0.3 0.29 10.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EAU86674.2 - 0.00051 19.2 1.6 0.4 9.7 0.0 2.6 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.1 EAU86674.2 - 0.00061 19.2 0.0 0.28 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 EAU86674.2 - 0.0015 17.3 0.8 0.34 9.6 0.1 2.3 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 EAU86674.2 - 0.0017 18.5 2.7 0.082 13.0 0.1 3.2 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EAU86674.2 - 0.003 17.4 0.4 2 8.3 0.1 3.9 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EAU86674.2 - 0.0095 15.7 1.8 0.55 10.0 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EAU86674.2 - 0.012 15.3 0.3 1.8 8.2 0.0 3.3 3 1 0 3 3 2 0 Archaeal ATPase AAA_30 PF13604.1 EAU86674.2 - 0.012 15.2 3.1 3 7.3 0.2 2.9 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EAU86674.2 - 0.012 14.5 0.2 10 4.9 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_17 PF13207.1 EAU86674.2 - 0.018 15.8 5.1 7.9 7.3 0.0 3.7 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.8 EAU86674.2 - 0.021 13.7 0.6 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 EAU86674.2 - 0.021 14.4 1.7 4.3 7.0 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EAU86674.2 - 0.022 13.6 0.9 5.7 5.7 0.1 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_10 PF12846.2 EAU86674.2 - 0.033 13.6 1.4 4 6.7 0.3 2.7 3 0 0 3 3 2 0 AAA-like domain TrwB_AAD_bind PF10412.4 EAU86674.2 - 0.045 12.3 1.0 4.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EAU86674.2 - 0.067 12.6 2.0 3.4 7.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SUFU_C PF12470.3 EAU86674.2 - 0.072 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain ATP_bind_1 PF03029.12 EAU86674.2 - 0.075 12.5 0.6 47 3.4 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 EAU86674.2 - 0.087 12.4 1.4 11 5.5 0.1 2.5 2 0 0 2 2 2 0 NACHT domain KAP_NTPase PF07693.9 EAU86674.2 - 0.094 11.6 0.0 4.2 6.2 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 EAU86674.2 - 0.18 12.1 3.5 18 5.6 0.0 3.8 4 0 0 4 4 3 0 AAA domain NTPase_1 PF03266.10 EAU86674.2 - 0.39 10.4 4.0 13 5.4 0.4 3.1 3 1 0 3 3 3 0 NTPase Fungal_trans PF04082.13 EAU86676.2 - 2.4e-26 92.1 0.0 4.1e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU86676.2 - 4.1e-10 39.4 10.8 8.8e-10 38.3 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.18 EAU86678.2 - 4e-28 98.5 0.0 3.8e-15 55.9 0.4 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EAU86678.2 - 0.0024 18.3 0.7 0.64 10.5 0.4 3.3 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EAU86678.2 - 0.075 12.8 1.7 1 9.2 0.1 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease POR_N PF01855.14 EAU86679.2 - 0.094 12.2 0.5 0.12 11.8 0.4 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Hydrolase PF00702.21 EAU86680.1 - 1.5e-14 54.9 0.4 8e-13 49.2 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU86680.1 - 9e-14 52.0 0.2 3.2e-12 47.0 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAU86680.1 - 7.2e-13 48.1 0.0 7.2e-13 48.1 0.0 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EAU86680.1 - 9.3e-13 47.9 0.0 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAU86680.1 - 0.0033 17.0 0.0 0.041 13.4 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAU86680.1 - 0.12 12.6 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glyco_trans_2_3 PF13632.1 EAU86690.2 - 1.6e-51 174.8 0.1 1.6e-51 174.8 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAU86690.2 - 1.7e-09 37.8 0.0 1.1e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAU86690.2 - 0.0012 18.5 0.0 0.0091 15.6 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAU86690.2 - 0.036 13.3 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 EAU86691.2 - 6e-25 87.5 0.3 2e-24 85.8 0.1 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 vATP-synt_E PF01991.13 EAU86692.1 - 1.4e-52 177.9 12.1 1.6e-52 177.6 8.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.6 EAU86692.1 - 2.4 7.2 6.9 3.3 6.7 4.8 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M zf-C2H2_6 PF13912.1 EAU86693.2 - 9.4e-15 53.9 7.8 0.0021 17.8 0.1 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU86693.2 - 2.9e-12 46.1 10.0 0.016 15.5 0.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.2 EAU86693.2 - 5e-12 45.5 3.6 0.25 11.6 0.0 4.5 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EAU86693.2 - 3.9e-10 39.3 14.3 0.044 14.1 0.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EAU86693.2 - 0.00025 21.1 2.9 6.6 6.9 0.0 4.1 2 1 2 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EAU86693.2 - 0.00055 20.0 0.7 11 6.2 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Fer4_21 PF14697.1 EAU86693.2 - 0.0045 16.7 4.0 4 7.3 0.2 3.9 4 0 0 4 4 4 1 4Fe-4S dicluster domain Rpr2 PF04032.11 EAU86693.2 - 0.0048 16.7 8.1 4.9 7.0 0.0 4.1 2 1 2 4 4 4 2 RNAse P Rpr2/Rpp21/SNM1 subunit domain RNA_POL_M_15KD PF02150.11 EAU86693.2 - 0.011 15.4 3.8 18 5.1 0.0 4.2 4 0 0 4 4 4 0 RNA polymerases M/15 Kd subunit zf-CHY PF05495.7 EAU86693.2 - 0.021 14.9 1.6 1.7 8.8 0.6 3.1 2 1 1 3 3 3 0 CHY zinc finger Nudix_N_2 PF14803.1 EAU86693.2 - 0.12 12.1 12.6 6.3 6.5 0.1 4.3 4 0 0 4 4 4 0 Nudix N-terminal zinc_ribbon_5 PF13719.1 EAU86693.2 - 0.17 11.4 8.0 4.9 6.8 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EAU86693.2 - 0.24 11.1 8.1 5.1 6.8 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 EAU86693.2 - 2.5 8.5 10.1 21 5.6 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Trm112p PF03966.11 EAU86693.2 - 4 7.8 7.5 56 4.2 0.0 4.0 3 2 1 4 4 4 0 Trm112p-like protein GMC_oxred_N PF00732.14 EAU86694.2 - 2.9e-67 226.8 0.0 3.7e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU86694.2 - 1.6e-32 112.8 0.0 2.6e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAU86694.2 - 5.5e-06 25.5 0.0 0.0019 17.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU86694.2 - 8e-05 22.5 0.0 0.00029 20.8 0.0 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU86694.2 - 0.00031 19.7 0.0 0.018 13.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EAU86694.2 - 0.00063 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EAU86694.2 - 0.0086 14.7 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EAU86694.2 - 0.0097 15.7 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EAU86694.2 - 0.01 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EAU86694.2 - 0.11 10.8 0.0 0.2 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EAU86695.2 - 2e-27 96.4 0.1 3.7e-27 95.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU86695.2 - 1.4e-11 44.6 0.5 7.5e-10 39.0 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU86695.2 - 2.2e-05 24.6 0.6 0.024 14.7 0.1 3.5 3 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EAU86695.2 - 0.027 14.7 0.1 0.43 10.8 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EAU86695.2 - 0.03 14.0 0.2 3.9 7.2 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding ICMT PF04140.9 EAU86696.2 - 1.5e-16 60.3 1.6 2.1e-16 59.9 0.1 2.0 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EAU86696.2 - 5e-12 45.8 0.8 1.1e-11 44.7 0.5 1.8 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EAU86696.2 - 2.6e-06 26.2 0.1 3.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EAU86696.2 - 0.071 12.3 1.9 0.065 12.5 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Lipase_GDSL PF00657.17 EAU86697.1 - 5.3e-21 75.5 0.0 6.3e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAU86697.1 - 1.1e-06 28.9 0.1 3.2e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SNARE PF05739.14 EAU86698.2 - 5.1e-07 29.2 0.0 6.3e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 SNARE domain Trep_Strep PF09605.5 EAU86698.2 - 0.017 14.7 0.1 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) RskA PF10099.4 EAU86698.2 - 0.031 14.0 0.1 0.033 13.9 0.0 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FtsX PF02687.16 EAU86698.2 - 0.036 13.8 0.4 0.044 13.5 0.3 1.1 1 0 0 1 1 1 0 FtsX-like permease family Synaptobrevin PF00957.16 EAU86698.2 - 0.081 12.5 0.1 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Synaptobrevin DUF2370 PF10176.4 EAU86698.2 - 0.091 12.0 0.0 0.1 11.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Herpes_US9 PF06072.6 EAU86698.2 - 0.095 12.5 1.9 0.16 11.8 1.3 1.4 1 1 0 1 1 1 0 Alphaherpesvirus tegument protein US9 UCR_TM PF02921.9 EAU86700.1 - 0.56 10.4 0.0 0.56 10.4 0.0 3.1 4 0 0 4 4 4 0 Ubiquinol cytochrome reductase transmembrane region ThiF PF00899.16 EAU86701.1 - 1.1e-38 132.1 0.0 2.1e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EAU86701.1 - 3.6e-28 96.9 0.1 7.3e-28 95.9 0.0 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EAU86701.1 - 1e-18 66.4 1.7 1e-18 66.4 1.2 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EAU86701.1 - 1.7e-05 24.7 0.1 3.5e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EAU86701.1 - 0.00013 22.1 0.0 0.00034 20.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EAU86701.1 - 0.036 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_71 PF03659.9 EAU86702.2 - 2.2e-86 289.7 0.1 2.7e-86 289.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.1 EAU86702.2 - 0.0094 15.1 0.0 2.7 7.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyltransferase WbsX Rad17 PF03215.10 EAU86703.2 - 2.9e-55 187.9 0.0 5.4e-54 183.7 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EAU86703.2 - 6.6e-05 23.1 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU86703.2 - 0.00013 22.7 0.1 0.00091 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAU86703.2 - 0.00019 21.5 0.0 0.00048 20.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU86703.2 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU86703.2 - 0.0022 18.0 0.0 0.0074 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EAU86703.2 - 0.0029 17.3 0.0 0.01 15.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAU86703.2 - 0.017 14.7 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAU86703.2 - 0.025 14.8 0.0 0.077 13.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EAU86703.2 - 0.06 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAU86703.2 - 0.098 11.8 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 3-HAO PF06052.7 EAU86705.2 - 3.6e-55 185.5 0.1 2.3e-52 176.4 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase FAD_binding_3 PF01494.14 EAU86707.2 - 2.6e-12 46.4 0.1 9.8e-06 24.8 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAU86707.2 - 1e-10 41.0 0.6 3e-06 26.3 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU86707.2 - 4.8e-08 32.9 1.0 2.3e-07 30.7 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EAU86707.2 - 1.2e-07 31.1 0.7 0.0051 15.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EAU86707.2 - 4.2e-07 29.1 0.3 7.5e-07 28.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EAU86707.2 - 4.9e-06 26.8 0.1 0.012 15.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU86707.2 - 1.1e-05 25.3 0.4 2.4e-05 24.3 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAU86707.2 - 8.5e-05 21.8 1.1 0.00019 20.6 0.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAU86707.2 - 0.0002 19.9 0.1 0.018 13.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 EAU86707.2 - 0.00032 19.7 0.4 0.0061 15.5 0.3 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EAU86707.2 - 0.001 17.9 0.4 0.0016 17.3 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EAU86707.2 - 0.005 16.9 0.3 0.011 15.7 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EAU86707.2 - 0.016 13.8 1.8 0.14 10.7 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase MFS_1 PF07690.11 EAU86708.2 - 1e-21 77.0 50.4 3.6e-18 65.4 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_M PF02770.14 EAU86709.2 - 2e-05 24.0 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EAU86709.2 - 0.00021 21.4 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DoxA PF07680.6 EAU86709.2 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 TQO small subunit DoxA PHD PF00628.24 EAU86710.2 - 5.8e-05 22.6 1.2 5.8e-05 22.6 0.8 2.8 3 0 0 3 3 3 1 PHD-finger Hydantoinase_B PF02538.9 EAU86711.2 - 7.8e-185 615.0 0.1 1.3e-184 614.3 0.0 1.3 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase WH1 PF00568.18 EAU86712.1 - 3.2e-20 71.8 0.0 4.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 EAU86712.1 - 6.3e-05 23.3 0.0 0.00017 21.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 EAU86712.1 - 0.03 13.9 0.1 0.078 12.6 0.0 1.8 1 0 0 1 1 1 0 WH2 motif Bacteriocin_IIc PF10439.4 EAU86712.1 - 0.046 13.8 13.0 0.11 12.6 9.0 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 EAU86712.1 - 2.2 7.9 15.5 4.8 6.8 10.7 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain GMC_oxred_N PF00732.14 EAU86715.2 - 1.1e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU86715.2 - 2.2e-34 118.8 0.0 3.6e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAU86715.2 - 1.2e-06 27.7 0.2 0.00016 20.6 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU86715.2 - 4e-05 23.5 0.1 0.00013 21.8 0.0 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU86715.2 - 0.00029 19.7 0.1 0.031 13.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EAU86715.2 - 0.002 17.0 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein TrkA_N PF02254.13 EAU86715.2 - 0.0027 17.6 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain Trp_halogenase PF04820.9 EAU86715.2 - 0.0048 15.5 0.0 0.0083 14.7 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EAU86715.2 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU86715.2 - 0.05 13.3 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EAU86715.2 - 0.092 11.1 0.0 0.14 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EAU86715.2 - 0.13 11.3 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family zf-C2H2 PF00096.21 EAU86716.1 - 2.7e-08 33.6 20.3 1.6e-05 24.9 1.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EAU86716.1 - 2.1e-07 30.7 14.4 0.026 14.7 0.7 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EAU86716.1 - 3.5e-07 30.0 18.8 0.00091 19.3 0.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU86716.1 - 2.9e-06 27.2 12.1 0.019 15.2 1.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain DUF3505 PF12013.3 EAU86716.1 - 0.0064 16.7 10.7 0.1 12.8 0.2 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF3505) GAGA PF09237.6 EAU86716.1 - 0.014 14.9 1.6 1.5 8.4 0.1 2.7 2 0 0 2 2 2 0 GAGA factor zf-C2H2_6 PF13912.1 EAU86716.1 - 0.024 14.5 0.2 0.024 14.5 0.2 3.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EAU86716.1 - 0.05 13.8 1.3 0.23 11.7 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAU86716.1 - 0.11 12.6 0.1 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EAU86716.1 - 0.16 12.3 8.7 1.7 9.1 2.3 2.3 1 1 1 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 EAU86716.1 - 1.2 9.3 7.4 0.63 10.2 1.2 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding VHS PF00790.14 EAU86719.1 - 7.1e-39 132.6 0.0 4.5e-38 130.0 0.0 2.2 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 EAU86719.1 - 1e-18 67.1 0.1 2.5e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 GAT domain GATase PF00117.23 EAU86721.1 - 1e-12 47.9 0.0 2.8e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAU86721.1 - 0.0012 18.3 0.1 0.0067 15.8 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 HTS PF04204.11 EAU86721.1 - 0.05 12.3 0.0 0.19 10.4 0.0 1.8 2 0 0 2 2 2 0 Homoserine O-succinyltransferase SNARE PF05739.14 EAU86722.2 - 3.3e-11 42.6 1.3 6.8e-11 41.7 0.9 1.5 1 0 0 1 1 1 1 SNARE domain DEC-1_N PF04625.8 EAU86722.2 - 0.034 12.8 4.5 0.048 12.3 3.1 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Mito_fiss_reg PF05308.6 EAU86722.2 - 6.4 6.0 13.9 0.58 9.4 5.3 1.9 1 1 1 2 2 2 0 Mitochondrial fission regulator Hydrophobin PF01185.13 EAU86723.2 - 5.8e-23 81.1 15.0 7.3e-23 80.8 10.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin EBP PF05241.7 EAU86724.2 - 2.1e-07 30.1 6.2 3.2e-07 29.5 4.3 1.2 1 0 0 1 1 1 1 Emopamil binding protein NADH_B2 PF14813.1 EAU86724.2 - 0.0083 15.7 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 UNC-50 PF05216.8 EAU86724.2 - 0.024 13.8 0.9 0.036 13.2 0.6 1.2 1 0 0 1 1 1 0 UNC-50 family EBP PF05241.7 EAU86726.1 - 4.5e-07 29.0 7.8 1e-06 27.8 5.4 1.5 1 1 0 1 1 1 1 Emopamil binding protein NADH_B2 PF14813.1 EAU86726.1 - 0.0042 16.7 0.6 0.0093 15.6 0.4 1.5 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SSF PF00474.12 EAU86727.1 - 7.2e-18 64.4 30.3 7.2e-18 64.4 21.0 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family zf-C2H2 PF00096.21 EAU86731.2 - 1.3e-09 37.8 13.0 6.3e-05 23.0 1.0 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU86731.2 - 5.7e-09 35.8 14.0 0.00041 20.4 0.6 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 EAU86731.2 - 6e-07 29.3 4.9 0.047 13.9 0.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EAU86731.2 - 1.3e-06 28.2 13.1 7.7e-05 22.7 1.0 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3505 PF12013.3 EAU86731.2 - 0.0065 16.6 4.9 1.8 8.8 0.1 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3505) zf-C2H2_jaz PF12171.3 EAU86731.2 - 0.19 11.9 1.6 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3317 PF11779.3 EAU86732.1 - 3e-07 29.7 6.9 4.8e-07 29.1 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) zf-C2H2 PF00096.21 EAU86733.1 - 1.6e-07 31.2 16.7 0.00014 21.9 1.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU86733.1 - 5.1e-06 26.4 17.3 0.0025 18.0 0.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU86733.1 - 1.1e-05 25.4 19.7 0.00032 20.8 1.0 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-H2C2_5 PF13909.1 EAU86733.1 - 0.00053 20.0 11.1 0.054 13.7 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EAU86733.1 - 0.0082 16.0 2.2 0.014 15.2 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger DUF230 PF03003.11 EAU86733.1 - 0.42 10.1 4.0 0.75 9.3 2.8 1.4 1 0 0 1 1 1 0 Poxvirus proteins of unknown function zf-TRAF PF02176.13 EAU86733.1 - 2.8 8.3 7.9 0.97 9.8 1.7 2.4 1 1 1 2 2 2 0 TRAF-type zinc finger DUF3317 PF11779.3 EAU86734.1 - 4.1e-07 29.3 5.8 5.8e-07 28.8 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) S4 PF01479.20 EAU86735.2 - 2.9e-10 39.4 0.0 5.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EAU86735.2 - 0.00026 20.5 0.1 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 S4 domain WD40 PF00400.27 EAU86737.2 - 9.8e-110 354.9 44.0 1.1e-12 47.3 0.2 9.6 9 0 0 9 9 9 9 WD domain, G-beta repeat PD40 PF07676.7 EAU86737.2 - 9e-12 44.3 8.5 12 5.6 0.0 9.3 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EAU86737.2 - 2.7e-11 43.3 20.9 6.7e-05 22.4 2.4 5.5 1 1 3 5 5 5 5 Lipoprotein LpqB beta-propeller domain NACHT PF05729.7 EAU86737.2 - 1.2e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Hanta_G2 PF01561.11 EAU86737.2 - 9.1e-06 24.3 2.2 6.5 5.0 0.0 5.8 3 1 4 7 7 7 3 Hantavirus glycoprotein G2 AAA_16 PF13191.1 EAU86737.2 - 1.7e-05 24.9 1.2 8.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Apolipoprotein PF01442.13 EAU86737.2 - 0.023 14.1 2.9 0.04 13.4 2.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain HGWP PF03578.10 EAU86737.2 - 0.055 12.7 1.7 0.2 10.9 1.2 2.0 1 0 0 1 1 1 0 HGWP repeat Torsin PF06309.6 EAU86737.2 - 0.076 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin APS_kinase PF01583.15 EAU86737.2 - 0.15 11.6 0.0 0.46 10.1 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase Ferric_reduct PF01794.14 EAU86738.1 - 4.3e-17 62.3 10.2 1.2e-16 60.9 7.1 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EAU86738.1 - 3.1e-13 49.5 0.0 5.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EAU86738.1 - 2.5e-10 40.4 0.0 1.7e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FA_desaturase PF00487.19 EAU86740.2 - 0.21 11.0 8.2 0.35 10.2 5.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase WD40 PF00400.27 EAU86743.2 - 5.4e-13 48.2 0.0 0.00033 20.4 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.2 EAU86743.2 - 6.1e-06 25.8 2.7 8.4e-05 22.2 0.2 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EAU86743.2 - 0.0031 17.1 0.5 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 EAU86743.2 - 0.0041 16.6 0.2 3.9 6.8 0.3 3.0 1 1 1 2 2 2 2 PQQ-like domain DUF619 PF04768.8 EAU86745.1 - 1.4e-42 144.9 0.0 2.3e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EAU86745.1 - 3.4e-21 75.7 0.0 9.4e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EAU86745.1 - 7.5e-20 71.4 0.0 1.4e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EAU86745.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EAU86745.1 - 0.067 13.7 0.0 0.37 11.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold AAA_22 PF13401.1 EAU86747.1 - 0.071 13.2 0.0 0.076 13.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain LANC_like PF05147.8 EAU86748.2 - 3.7e-28 98.1 0.0 1.3e-26 93.0 0.0 2.1 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Glyoxal_oxid_N PF07250.6 EAU86749.1 - 2.3e-37 128.3 0.0 4.3e-33 114.3 0.0 4.1 3 1 0 3 3 3 3 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EAU86749.1 - 3.3e-20 72.0 0.2 9.1e-20 70.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EAU86749.1 - 3.9e-05 23.3 8.8 0.021 14.6 0.1 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Lactonase PF10282.4 EAU86750.2 - 3.2e-34 118.5 0.0 3.5e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lactonase PF10282.4 EAU86751.1 - 5.3e-36 124.3 0.0 6.1e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Grp1_Fun34_YaaH PF01184.14 EAU86752.1 - 5.1e-68 228.5 16.3 6.3e-68 228.2 11.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 EAU86752.1 - 0.23 10.4 4.3 0.37 9.7 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Glyco_transf_90 PF05686.7 EAU86753.2 - 2e-19 69.5 0.1 3.5e-17 62.1 0.0 2.4 3 0 0 3 3 3 2 Glycosyl transferase family 90 Profilin PF00235.14 EAU86754.1 - 8.1e-37 126.0 0.2 9.2e-37 125.8 0.1 1.0 1 0 0 1 1 1 1 Profilin Gly-zipper_OmpA PF13436.1 EAU86754.1 - 0.017 14.7 1.2 0.029 14.0 0.8 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Reo_sigmaC PF04582.7 EAU86755.1 - 0.0027 16.9 3.9 0.0079 15.4 1.5 2.2 2 0 0 2 2 2 1 Reovirus sigma C capsid protein MbeD_MobD PF04899.7 EAU86755.1 - 0.19 11.6 0.1 0.19 11.6 0.0 4.1 3 1 2 5 5 5 0 MbeD/MobD like Fib_alpha PF08702.5 EAU86755.1 - 0.51 10.4 10.3 0.52 10.4 2.2 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EAU86755.1 - 0.64 9.9 3.4 3.2 7.6 0.0 3.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) LXG PF04740.7 EAU86755.1 - 1.1 8.9 16.0 0.8 9.4 0.8 3.8 2 1 2 4 4 4 0 LXG domain of WXG superfamily DUF2450 PF10475.4 EAU86755.1 - 9.3 5.0 6.2 1.4 7.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) F-box PF00646.28 EAU86757.2 - 8.8e-06 25.2 1.5 8.8e-06 25.2 1.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAU86757.2 - 0.00014 21.4 0.7 0.00051 19.7 0.5 2.0 1 0 0 1 1 1 1 F-box-like L51_S25_CI-B8 PF05047.11 EAU86759.1 - 2.5e-10 39.9 0.0 3.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RGS PF00615.14 EAU86760.1 - 1.8e-10 40.9 0.7 3e-05 24.0 0.2 2.7 2 1 0 2 2 2 2 Regulator of G protein signaling domain EF-hand_1 PF00036.27 EAU86762.2 - 6.5e-31 103.2 7.2 4.3e-10 38.1 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EAU86762.2 - 5.3e-29 99.5 5.0 2.5e-14 52.6 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EAU86762.2 - 4.2e-27 94.0 1.6 5.1e-19 68.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EAU86762.2 - 1.5e-20 71.5 4.7 2.6e-07 29.6 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EAU86762.2 - 8.6e-20 68.7 4.0 2e-09 36.5 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.1 EAU86762.2 - 6.4e-09 35.5 0.2 0.00061 19.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EAU86762.2 - 1e-07 31.6 1.3 0.00039 20.1 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EAU86762.2 - 1.8e-06 27.9 0.0 0.00026 20.9 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EAU86762.2 - 5.6e-06 25.8 0.1 0.11 12.1 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EAU86762.2 - 0.00037 20.4 0.1 0.0025 17.7 0.0 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 EAU86762.2 - 0.019 14.3 1.0 0.025 13.9 0.7 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DUF1880 PF08976.6 EAU86762.2 - 0.071 13.2 0.0 5.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF3349 PF11829.3 EAU86762.2 - 0.094 13.1 0.3 6.2 7.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) SPX PF03105.14 EAU86763.2 - 1.7e-23 83.7 0.0 1.1e-22 81.0 0.0 2.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EAU86763.2 - 6.4e-08 32.3 7.8 1.2e-07 31.4 5.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAU86763.2 - 3.8e-07 29.6 8.3 6.9e-07 28.8 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU86763.2 - 4e-07 29.6 6.4 6.3e-07 28.9 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU86763.2 - 5.7e-07 29.2 7.6 9.9e-07 28.4 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAU86763.2 - 3e-06 27.1 9.7 5.1e-06 26.4 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU86763.2 - 4.6e-05 23.0 7.7 8.7e-05 22.1 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EAU86763.2 - 0.00017 21.1 2.5 0.00033 20.1 1.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EAU86763.2 - 0.0021 17.7 8.6 0.0029 17.2 4.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EAU86763.2 - 0.023 14.5 1.3 0.04 13.7 0.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EAU86763.2 - 0.028 13.9 5.7 0.076 12.5 3.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EAU86763.2 - 0.03 14.1 3.6 0.065 13.0 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EAU86763.2 - 0.074 13.1 5.3 0.18 11.9 3.7 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 EAU86763.2 - 0.69 9.4 5.9 1.2 8.6 4.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger p450 PF00067.17 EAU86764.1 - 2.8e-65 220.6 0.0 3.6e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NfeD PF01957.13 EAU86765.1 - 2.4 8.2 6.4 9.9 6.2 4.4 1.8 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding 4HB_MCP_1 PF12729.2 EAU86765.1 - 8.6 5.6 6.1 4.9 6.4 0.1 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction GLE1 PF07817.8 EAU86766.1 - 9.5e-33 113.2 0.0 9.6e-23 80.4 0.0 4.8 2 1 2 5 5 5 2 GLE1-like protein DUF3870 PF12986.2 EAU86767.1 - 7e-05 23.0 10.7 72 3.7 0.0 7.6 7 1 1 8 8 8 0 Domain of unknown function (DUF3870) Strep_his_triad PF04270.8 EAU86767.1 - 0.00066 19.3 0.0 43 3.9 0.0 5.7 6 0 0 6 6 6 0 Streptococcal histidine triad protein DUF2191 PF09957.4 EAU86767.1 - 0.0034 17.1 8.3 13 5.6 0.0 5.0 5 0 0 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2191) Hormone_2 PF00123.15 EAU86767.1 - 0.049 13.4 2.7 65 3.4 0.0 5.4 7 0 0 7 7 7 0 Peptide hormone ThiS PF02597.15 EAU86767.1 - 0.068 13.5 2.4 2.1e+02 2.4 0.0 5.2 3 2 3 6 6 6 0 ThiS family DUF3040 PF11239.3 EAU86767.1 - 1.8 8.6 0.0 1.8 8.6 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF3040) Mito_fiss_reg PF05308.6 EAU86768.1 - 0.078 12.3 2.9 0.084 12.2 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator eIF3_subunit PF08597.5 EAU86768.1 - 1.2 8.5 6.9 1.6 8.2 4.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pex14_N PF04695.8 EAU86769.2 - 3.6 7.6 8.1 31 4.5 3.4 3.2 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suc_Fer-like PF06999.7 EAU86770.2 - 6.3e-24 85.2 0.0 2.5e-23 83.2 0.0 1.8 2 0 0 2 2 2 1 Sucrase/ferredoxin-like ABC_tran PF00005.22 EAU86771.2 - 1.8e-55 186.9 0.3 4.6e-31 107.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAU86771.2 - 1.4e-49 168.9 34.5 1.2e-26 93.8 8.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EAU86771.2 - 4.3e-11 42.4 3.5 0.0012 18.1 0.1 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU86771.2 - 2.4e-09 37.5 2.2 0.033 14.1 0.0 4.6 3 2 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EAU86771.2 - 6.9e-08 32.4 1.4 0.0052 16.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EAU86771.2 - 2.2e-07 31.3 0.5 0.0044 17.5 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EAU86771.2 - 3e-06 26.6 0.1 0.032 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU86771.2 - 8e-06 25.9 2.6 0.0049 16.8 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EAU86771.2 - 4.5e-05 22.7 1.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EAU86771.2 - 0.00012 22.0 3.2 0.037 13.8 0.2 2.7 2 0 0 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 EAU86771.2 - 0.00014 21.4 0.1 0.41 10.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 EAU86771.2 - 0.00021 21.4 1.4 0.082 13.0 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EAU86771.2 - 0.00025 21.8 0.0 0.93 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAU86771.2 - 0.00033 20.1 0.0 0.78 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EAU86771.2 - 0.00042 19.1 0.4 0.29 9.8 0.0 2.2 2 0 0 2 2 2 2 ArgK protein Zeta_toxin PF06414.7 EAU86771.2 - 0.00081 18.5 0.8 0.71 8.9 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.1 EAU86771.2 - 0.0011 18.0 0.7 0.088 11.8 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EAU86771.2 - 0.0013 19.0 2.6 2 8.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EAU86771.2 - 0.0026 17.2 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EAU86771.2 - 0.0034 17.7 7.0 0.12 12.7 0.0 3.3 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.8 EAU86771.2 - 0.0044 15.9 2.1 0.25 10.2 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) SbcCD_C PF13558.1 EAU86771.2 - 0.0052 16.6 0.0 0.66 9.9 0.0 2.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EAU86771.2 - 0.011 14.7 0.0 1.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EAU86771.2 - 0.017 14.7 1.8 4 6.9 0.2 2.8 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EAU86771.2 - 0.018 14.7 1.2 5.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EAU86771.2 - 0.02 13.7 0.2 4.1 6.1 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EAU86771.2 - 0.021 14.5 0.3 1.5 8.4 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase KAP_NTPase PF07693.9 EAU86771.2 - 0.023 13.7 0.0 0.86 8.5 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain TrwB_AAD_bind PF10412.4 EAU86771.2 - 0.026 13.1 0.6 2.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 EAU86771.2 - 0.034 14.3 0.1 12 6.1 0.0 3.1 3 0 0 3 3 3 0 RNA helicase cobW PF02492.14 EAU86771.2 - 0.039 13.3 1.1 4.2 6.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EAU86771.2 - 0.07 12.7 1.0 9.9 5.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 EAU86771.2 - 0.072 12.5 0.4 7 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EAU86771.2 - 0.15 11.8 5.6 0.92 9.2 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 UPF0079 PF02367.12 EAU86771.2 - 0.19 11.3 1.6 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EAU86771.2 - 0.25 10.7 2.7 7.3 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain NPR3 PF03666.8 EAU86771.2 - 0.76 8.2 2.3 1.5 7.2 1.6 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRM_1 PF00076.17 EAU86772.1 - 1e-57 191.6 0.0 4e-16 58.3 0.0 6.9 6 1 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU86772.1 - 3.2e-44 148.7 0.0 1.7e-12 47.1 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU86772.1 - 1.5e-12 47.1 0.0 0.0093 15.7 0.1 5.5 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBX PF00789.15 EAU86775.1 - 7.2e-11 41.9 0.0 3e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 UBX domain CAF-1_p150 PF11600.3 EAU86775.1 - 2.8e-05 23.6 15.9 6.4e-05 22.4 11.0 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal UBA_4 PF14555.1 EAU86775.1 - 3.1e-05 23.4 0.0 6.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Borrelia_P83 PF05262.6 EAU86775.1 - 0.21 9.7 4.6 0.29 9.3 3.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Ank PF00023.25 EAU86776.2 - 5e-137 439.4 49.3 9.8e-08 31.4 0.0 25.5 25 1 1 26 26 26 23 Ankyrin repeat Ank_2 PF12796.2 EAU86776.2 - 1.7e-124 406.4 16.7 1.3e-14 54.3 0.0 13.2 2 2 12 14 14 14 14 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU86776.2 - 3.2e-98 320.5 20.9 1.3e-11 44.6 0.0 18.2 9 6 7 17 17 17 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU86776.2 - 4.3e-92 292.7 15.5 6.4e-05 22.8 0.0 25.3 26 0 0 26 26 26 21 Ankyrin repeat Ank_5 PF13857.1 EAU86776.2 - 1.7e-79 260.0 45.7 6e-08 32.6 0.7 18.3 5 4 16 21 21 21 21 Ankyrin repeats (many copies) NB-ARC PF00931.17 EAU86776.2 - 2.2e-07 30.0 0.0 4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EAU86776.2 - 0.0022 17.6 0.0 0.0054 16.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU86776.2 - 0.028 14.4 0.0 0.076 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EAU86776.2 - 0.057 12.3 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAU86776.2 - 0.061 13.4 0.0 0.36 10.9 0.0 2.3 2 1 1 3 3 3 0 AAA domain EF-hand_7 PF13499.1 EAU86777.2 - 4.1e-13 49.2 0.0 1.7e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EAU86777.2 - 1.4e-11 43.2 0.4 4.3e-05 23.0 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EAU86777.2 - 3.3e-10 38.5 0.1 0.00034 19.7 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EAU86777.2 - 3.7e-06 26.4 0.0 0.00013 21.5 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 EAU86777.2 - 5.6e-06 26.1 0.0 0.0075 16.1 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EAU86777.2 - 0.02 14.5 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) SapB_1 PF05184.10 EAU86777.2 - 0.048 13.4 0.0 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 EF-hand_5 PF13202.1 EAU86777.2 - 0.11 11.8 0.2 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 EF hand DUF221 PF02714.10 EAU86779.2 - 4.8e-74 249.1 29.7 8.2e-34 116.9 2.9 3.2 3 0 0 3 3 3 3 Domain of unknown function DUF221 DUF4463 PF14703.1 EAU86779.2 - 9.8e-15 54.8 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 EAU86779.2 - 8.4e-10 38.4 5.2 2.7e-05 23.7 0.0 4.3 4 0 0 4 4 4 2 Late exocytosis, associated with Golgi transport RRM_1 PF00076.17 EAU86779.2 - 0.018 14.6 0.2 0.58 9.8 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU86779.2 - 0.072 13.0 0.1 2.5 8.1 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 EAU86782.2 - 1.6e-36 124.5 3.1 2.9e-36 123.7 2.1 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EAU86782.2 - 5.3e-32 109.9 0.0 1.2e-31 108.8 0.0 1.7 1 0 0 1 1 1 1 PCRF domain DUF3050 PF11251.3 EAU86783.2 - 0.093 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Hyd_WA PF06462.7 EAU86783.2 - 0.21 11.2 1.3 0.47 10.1 0.2 2.2 2 0 0 2 2 2 0 Propeller LRR_4 PF12799.2 EAU86783.2 - 6 6.5 6.5 9.2 6.0 0.0 4.3 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) DUF1744 PF08490.7 EAU86784.2 - 4.5e-108 361.3 0.0 7.6e-108 360.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EAU86784.2 - 1.5e-63 214.6 0.6 3e-63 213.6 0.3 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EAU86784.2 - 9.5e-21 74.1 0.0 1.2e-18 67.1 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EAU86784.2 - 2.6e-07 30.3 0.2 9e-07 28.6 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EAU86784.2 - 0.00065 19.5 0.0 0.0023 17.7 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily zf-C4pol PF14260.1 EAU86784.2 - 0.035 14.1 5.2 0.095 12.7 3.6 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Hydrolase PF00702.21 EAU86785.2 - 2.2e-23 83.8 0.0 1.1e-22 81.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU86785.2 - 4.7e-23 82.3 0.0 9.3e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EAU86785.2 - 9.7e-23 80.4 0.4 3.4e-22 78.5 0.3 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EAU86785.2 - 0.00029 20.7 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAU86785.2 - 0.0075 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L38e PF01781.13 EAU86786.1 - 8.9e-32 108.6 1.1 1.1e-31 108.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF2344 PF10105.4 EAU86786.1 - 0.071 12.5 0.2 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Tetraspannin PF00335.15 EAU86787.1 - 7.8e-07 28.5 5.9 7.8e-07 28.5 4.1 1.5 1 1 1 2 2 2 1 Tetraspanin family ABC2_membrane_4 PF12730.2 EAU86787.1 - 0.19 10.8 10.2 0.21 10.6 6.4 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 EAU86787.1 - 0.24 10.3 5.9 0.32 9.9 4.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4149 PF13664.1 EAU86787.1 - 1.1 9.3 6.1 16 5.6 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Longin PF13774.1 EAU86788.1 - 2.2e-17 62.3 0.1 3.7e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EAU86788.1 - 8.4e-15 54.1 1.1 1.4e-14 53.4 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin An_peroxidase PF03098.10 EAU86789.2 - 9.2e-70 235.5 0.0 1.6e-67 228.0 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EAU86789.2 - 2.5e-06 26.2 0.0 6e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 Myosin_head PF00063.16 EAU86790.2 - 3.2e-238 792.2 0.0 3.2e-238 792.2 0.0 3.3 4 0 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EAU86790.2 - 2.4e-28 98.4 311.4 2.2e-22 78.6 83.3 5.8 2 2 1 3 3 3 2 Myosin tail Myosin_N PF02736.14 EAU86790.2 - 1.8e-10 40.3 0.7 4.9e-10 38.9 0.5 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EAU86790.2 - 0.026 14.6 0.1 0.026 14.6 0.0 5.3 5 0 0 5 5 5 0 AAA domain AAA_19 PF13245.1 EAU86790.2 - 0.039 13.7 0.0 0.19 11.4 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain IQ PF00612.22 EAU86790.2 - 0.26 11.0 4.5 0.26 11.0 0.4 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif Pkinase PF00069.20 EAU86791.2 - 8.3e-63 211.9 0.0 1.1e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86791.2 - 8.1e-28 97.1 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EAU86791.2 - 1.1e-11 45.0 2.6 3.2e-11 43.5 1.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain MARVEL PF01284.18 EAU86795.2 - 0.0001 22.1 12.6 0.00015 21.5 8.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.1 EAU86795.2 - 0.016 15.3 0.1 0.016 15.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Sensor PF13796.1 EAU86795.2 - 0.04 13.5 2.7 0.08 12.5 1.9 1.4 1 0 0 1 1 1 0 Putative sensor Ninjurin PF04923.7 EAU86795.2 - 0.13 11.9 4.1 0.41 10.3 3.0 1.8 1 1 1 2 2 2 0 Ninjurin Fig1 PF12351.3 EAU86795.2 - 3.1 7.6 10.3 3 7.6 6.7 1.3 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Glyco_hydro_18 PF00704.23 EAU86796.2 - 7.2e-66 222.9 7.9 1e-54 186.2 3.7 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 EAU86796.2 - 9.1e-12 44.3 9.0 9.1e-12 44.3 6.2 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain CBM_5_12_2 PF14600.1 EAU86796.2 - 0.006 16.1 5.1 0.022 14.3 3.6 2.0 1 0 0 1 1 1 1 Cellulose-binding domain Ras PF00071.17 EAU86797.1 - 3.7e-34 117.4 0.3 4.4e-34 117.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU86797.1 - 2.1e-23 83.0 0.1 7.9e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EAU86797.1 - 7.3e-08 31.8 0.2 9e-08 31.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EAU86797.1 - 7.8e-08 31.7 0.1 1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EAU86797.1 - 0.0089 14.7 0.7 0.027 13.1 0.1 2.1 1 1 2 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EAU86797.1 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.6 EAU86797.1 - 0.12 11.0 0.1 9.5 4.7 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.4 EAU86797.1 - 0.13 11.7 0.3 0.55 9.7 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GMC_oxred_C PF05199.8 EAU86798.2 - 1.6e-18 67.3 0.0 3.5e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EAU86798.2 - 9.1e-17 61.1 0.0 2.5e-16 59.7 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAU86798.2 - 2e-11 43.4 0.2 1.6e-06 27.2 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAU86798.2 - 2.2e-07 30.0 0.1 0.00011 21.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EAU86798.2 - 2.2e-06 27.6 0.1 7.2e-06 25.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EAU86798.2 - 8.7e-06 24.9 0.0 0.00043 19.4 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EAU86798.2 - 4.3e-05 22.7 0.0 0.016 14.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EAU86798.2 - 4.7e-05 23.3 0.0 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU86798.2 - 0.00016 20.2 0.1 0.00025 19.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EAU86798.2 - 0.00019 20.6 0.1 0.0003 19.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EAU86798.2 - 0.0015 18.5 0.0 0.01 15.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAU86798.2 - 0.056 12.3 0.1 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EAU86798.2 - 0.084 13.2 0.2 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAU86798.2 - 0.13 11.1 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A rRNA_proc-arch PF13234.1 EAU86800.2 - 1e-98 329.7 0.2 1.7e-98 329.0 0.0 1.5 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EAU86800.2 - 2e-59 199.8 0.5 2e-59 199.8 0.4 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EAU86800.2 - 6.3e-21 74.5 0.3 3.4e-20 72.1 0.0 2.5 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU86800.2 - 9.2e-07 28.6 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EAU86800.2 - 0.0063 15.4 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EAU86800.2 - 0.014 15.4 0.5 0.83 9.7 0.0 3.1 3 1 0 3 3 3 0 AAA domain Catalase PF00199.14 EAU86801.2 - 7.3e-176 584.5 1.2 9.1e-176 584.1 0.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EAU86801.2 - 1.9e-17 62.8 0.1 4.1e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Ribosomal_L14 PF00238.14 EAU86802.2 - 1.2e-33 115.4 0.0 1.4e-33 115.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Paf67 PF10255.4 EAU86804.1 - 1.2e-145 485.4 0.1 4.4e-145 483.5 0.1 1.8 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EAU86804.1 - 0.045 13.6 0.0 0.37 10.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF452 PF04301.8 EAU86819.2 - 0.044 13.0 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF452) Apolipoprotein PF01442.13 EAU86822.2 - 0.11 11.9 0.6 0.13 11.7 0.4 1.0 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tet_JBP PF12851.2 EAU86835.2 - 3.1e-14 52.6 0.0 4.4e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily zf-C4_ClpX PF06689.8 EAU86835.2 - 0.17 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger HMG_box_2 PF09011.5 EAU86838.1 - 0.015 15.6 0.4 0.041 14.2 0.3 1.8 1 0 0 1 1 1 0 HMG-box domain GTF2I PF02946.9 EAU86838.1 - 0.021 14.6 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 GTF2I-like repeat HMG_box PF00505.14 EAU86838.1 - 0.062 13.5 0.1 0.88 9.8 0.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box Nop14 PF04147.7 EAU86838.1 - 4.3 5.1 8.6 6.1 4.6 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family WEMBL PF05701.6 EAU86839.1 - 1.1e-05 24.0 4.7 1.9e-05 23.3 3.3 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 EAU86839.1 - 2.3e-05 24.2 2.7 2.3e-05 24.2 1.9 3.4 2 1 2 4 4 4 3 Tropomyosin like DUF3584 PF12128.3 EAU86839.1 - 0.0055 14.1 4.9 0.01 13.2 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 EAU86839.1 - 0.033 14.0 2.3 0.75 9.6 0.6 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EAU86839.1 - 0.04 13.8 1.3 0.57 10.1 0.4 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 EAU86839.1 - 0.069 13.0 0.5 0.3 10.9 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IFT46_B_C PF12317.3 EAU86839.1 - 0.13 11.5 0.0 0.39 10.0 0.1 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Reo_sigmaC PF04582.7 EAU86839.1 - 0.18 10.9 0.7 0.5 9.4 0.4 1.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EAU86839.1 - 0.38 8.5 3.3 0.7 7.6 2.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 EAU86839.1 - 1.1 7.6 6.5 1.2 7.5 3.8 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Ank_2 PF12796.2 EAU86841.2 - 9.2e-108 352.8 18.7 6.2e-14 52.1 0.1 12.6 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EAU86841.2 - 6.9e-107 344.3 43.6 4.3e-07 29.4 0.1 21.8 22 0 0 22 22 22 19 Ankyrin repeat Ank_4 PF13637.1 EAU86841.2 - 8.8e-83 271.3 26.7 5.5e-09 36.2 0.1 16.3 6 3 12 18 18 18 17 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU86841.2 - 3.1e-77 246.7 8.5 0.0021 18.1 0.0 21.2 21 0 0 21 21 21 16 Ankyrin repeat Ank_5 PF13857.1 EAU86841.2 - 1.1e-76 251.0 41.2 5.2e-08 32.8 0.3 16.1 4 2 15 19 19 19 17 Ankyrin repeats (many copies) NapD PF03927.8 EAU86841.2 - 2.5e-14 52.8 5.9 3.1 7.6 0.0 10.4 4 3 7 11 11 11 6 NapD protein SchA_CurD PF04486.7 EAU86841.2 - 7.3e-06 25.7 0.7 11 5.9 0.0 7.1 5 2 1 7 7 7 1 SchA/CurD like domain Pyridox_oxidase PF01243.15 EAU86841.2 - 0.0061 16.5 0.0 0.48 10.4 0.0 2.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase AAA_18 PF13238.1 EAU86841.2 - 0.08 13.2 0.0 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HEAT_2 PF13646.1 EAU86841.2 - 0.16 12.2 2.0 42 4.5 0.0 4.2 4 0 0 4 4 4 0 HEAT repeats AAA_12 PF13087.1 EAU86842.2 - 3.9e-50 170.0 0.0 6.7e-50 169.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU86842.2 - 5.9e-40 137.3 2.1 3.5e-20 72.5 0.0 3.0 3 1 1 4 4 3 2 AAA domain Dna2 PF08696.6 EAU86842.2 - 3.6e-18 65.6 0.0 9e-18 64.3 0.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_30 PF13604.1 EAU86842.2 - 7.8e-13 48.4 0.0 3.6e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU86842.2 - 4e-09 36.1 1.1 1.5e-08 34.2 0.1 2.4 3 0 0 3 3 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EAU86842.2 - 2.3e-06 27.2 0.1 1.1 8.7 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EAU86842.2 - 2.5e-05 24.3 0.0 6.3e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 EAU86842.2 - 0.0006 19.4 0.0 0.0045 16.6 0.0 2.2 1 1 0 1 1 1 1 Helicase Cas_Cas4 PF01930.12 EAU86842.2 - 0.00064 19.6 0.7 0.008 16.1 0.0 2.6 3 0 0 3 3 2 1 Domain of unknown function DUF83 ResIII PF04851.10 EAU86842.2 - 0.0025 17.6 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EAU86842.2 - 0.0031 16.9 0.2 0.0079 15.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain UvrD-helicase PF00580.16 EAU86842.2 - 0.0036 16.6 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EAU86842.2 - 0.0055 15.7 0.0 0.013 14.4 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) CbiA PF01656.18 EAU86842.2 - 0.007 15.7 0.1 0.02 14.3 0.0 1.7 2 0 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EAU86842.2 - 0.0083 16.0 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EAU86842.2 - 0.0095 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EAU86842.2 - 0.011 15.1 0.1 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EAU86842.2 - 0.02 14.3 0.6 0.076 12.4 0.1 2.2 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EAU86842.2 - 0.044 13.4 0.1 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EAU86842.2 - 0.059 12.2 0.5 0.12 11.3 0.4 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EAU86842.2 - 0.071 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EAU86842.2 - 0.082 12.8 0.2 0.46 10.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EAU86842.2 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase IstB_IS21 PF01695.12 EAU86842.2 - 0.16 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ribosomal_L24e PF01246.15 EAU86843.1 - 4.6e-30 103.2 0.5 4.6e-30 103.2 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e MAD PF05557.8 EAU86843.1 - 0.0041 15.2 0.3 0.0044 15.1 0.2 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein EF-hand_1 PF00036.27 EAU86845.2 - 3.3e-43 141.7 11.9 2.6e-10 38.8 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAU86845.2 - 1.3e-38 130.9 3.1 2.9e-21 75.3 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAU86845.2 - 7.4e-35 118.3 10.6 8.4e-17 60.5 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EAU86845.2 - 5.9e-32 106.6 6.1 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAU86845.2 - 6.3e-29 98.0 6.4 8.3e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EAU86845.2 - 5.7e-15 54.9 0.1 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EAU86845.2 - 1e-10 41.2 0.7 2.8e-05 23.7 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EAU86845.2 - 2.4e-09 37.1 0.0 0.00025 21.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EAU86845.2 - 2.3e-08 33.5 0.7 0.0099 15.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EAU86845.2 - 1.2e-06 28.3 1.3 1.7e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.6 EAU86845.2 - 0.00031 20.2 1.2 0.00036 20.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 EAU86845.2 - 0.00038 20.0 0.1 0.038 13.5 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein EF-hand_like PF09279.6 EAU86845.2 - 0.00066 19.6 0.5 0.011 15.7 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like TerB PF05099.8 EAU86845.2 - 0.0018 18.0 0.1 0.27 10.9 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.5 EAU86845.2 - 0.013 15.2 0.2 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 EAU86845.2 - 0.018 14.7 0.1 3.8 7.3 0.0 3.0 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.11 EAU86845.2 - 0.026 14.5 1.2 4.9 7.1 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EAU86845.2 - 0.042 13.3 0.1 0.8 9.2 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 EAU86845.2 - 0.054 13.8 0.6 13 6.2 0.0 2.6 1 1 2 3 3 3 0 Toprim-like LNS2 PF08235.8 EAU86845.2 - 0.13 11.8 0.1 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) VCBS PF13517.1 EAU86845.2 - 6.8 7.1 6.7 19 5.6 0.4 2.6 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella tRNA-synt_2b PF00587.20 EAU86846.1 - 9.7e-65 217.3 0.0 1.7e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EAU86846.1 - 2.4e-23 81.8 0.1 5.7e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF4199 PF13858.1 EAU86847.1 - 0.064 13.1 0.6 0.71 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF4218 PF13960.1 EAU86850.2 - 0.0033 16.8 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PRANC PF09372.5 EAU86856.1 - 0.0065 16.4 0.0 0.012 15.5 0.0 1.4 2 0 0 2 2 2 1 PRANC domain MFS_1 PF07690.11 EAU86868.2 - 1.3e-22 79.9 41.3 1.3e-22 79.9 28.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Pyridox_oxidase PF01243.15 EAU86871.2 - 0.00022 21.2 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Bestrophin PF01062.16 EAU86873.1 - 3.7e-48 163.9 4.2 1e-30 106.6 0.1 2.3 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel BaxI_1 PF12811.2 EAU86873.1 - 0.091 11.9 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like TP2 PF01254.13 EAU86876.1 - 2.3 8.5 5.9 2.7 8.3 4.1 1.1 1 0 0 1 1 1 0 Nuclear transition protein 2 APG12 PF04110.8 EAU86877.2 - 8.2e-30 102.8 0.0 1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EAU86877.2 - 0.024 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like SUI1 PF01253.17 EAU86878.1 - 1.9e-21 75.6 1.1 3.9e-21 74.6 0.8 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EAU86878.1 - 0.0011 18.7 0.2 0.0018 18.1 0.1 1.2 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Spore_III_AF PF09581.5 EAU86878.1 - 0.81 9.5 7.2 1.2 8.9 5.0 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Ank_2 PF12796.2 EAU86880.2 - 2.5e-118 386.6 27.2 1.6e-16 60.3 0.4 7.7 2 1 8 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EAU86880.2 - 2.1e-88 285.9 35.1 1.3e-07 31.0 0.1 16.1 16 0 0 16 16 16 14 Ankyrin repeat Ank_4 PF13637.1 EAU86880.2 - 2.3e-60 199.9 27.3 3.4e-09 36.9 0.1 10.5 3 2 9 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU86880.2 - 2.4e-59 191.3 17.3 0.0025 17.8 0.1 15.8 15 0 0 15 15 15 11 Ankyrin repeat Ank_5 PF13857.1 EAU86880.2 - 3.8e-58 192.2 31.0 1.2e-06 28.5 0.1 13.3 3 3 10 13 13 13 13 Ankyrin repeats (many copies) NB-ARC PF00931.17 EAU86880.2 - 4.4e-05 22.4 0.0 7.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EAU86880.2 - 0.003 17.2 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EAU86880.2 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Acetyltransf_1 PF00583.19 EAU86882.2 - 4.7e-11 42.5 0.1 7.6e-11 41.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU86882.2 - 1.1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU86882.2 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAU86882.2 - 0.0082 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GHL6 PF14871.1 EAU86882.2 - 0.01 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 SR-25 PF10500.4 EAU86884.2 - 0.4 10.1 8.5 0.7 9.3 5.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DDDD PF10161.4 EAU86888.1 - 0.051 13.2 0.1 0.24 11.0 0.1 2.3 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Ribosomal_60s PF00428.14 EAU86894.2 - 1.3 9.5 12.4 0.27 11.6 0.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-CCHH PF10283.4 EAU86895.2 - 2.4 8.0 4.6 0.61 9.9 1.0 1.6 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif DUF812 PF05667.6 EAU86897.2 - 0.017 13.6 2.2 0.022 13.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 EAU86897.2 - 0.13 10.1 0.1 0.14 9.9 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin PF00261.15 EAU86897.2 - 0.19 10.7 9.7 0.14 11.1 3.9 2.1 1 1 0 1 1 1 0 Tropomyosin DivIVA PF05103.8 EAU86897.2 - 2.4 8.2 7.6 6.1 6.8 5.3 1.6 1 1 0 1 1 1 0 DivIVA protein VP_N-CPKC PF11475.3 EAU86898.2 - 0.018 14.5 0.1 0.067 12.7 0.0 2.0 1 0 0 1 1 1 0 Virion protein N terminal domain ABC_tran PF00005.22 EAU86903.2 - 1.4e-19 70.7 0.0 2.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU86903.2 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EAU86903.2 - 5.8e-05 23.5 0.0 0.037 14.5 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EAU86903.2 - 0.00039 19.8 0.3 0.001 18.5 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU86903.2 - 0.002 18.1 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EAU86903.2 - 0.0083 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAU86903.2 - 0.009 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EAU86903.2 - 0.013 15.2 0.2 0.022 14.4 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 EAU86903.2 - 0.015 13.8 0.0 0.02 13.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU86903.2 - 0.015 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAU86903.2 - 0.016 15.9 0.4 0.039 14.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAU86903.2 - 0.019 14.3 0.1 0.044 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU86903.2 - 0.022 14.4 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 EAU86903.2 - 0.023 13.9 0.5 0.058 12.6 0.2 1.7 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EAU86903.2 - 0.048 12.2 0.0 0.37 9.3 0.0 1.9 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_19 PF13245.1 EAU86903.2 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EAU86903.2 - 0.05 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EAU86903.2 - 0.072 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EAU86903.2 - 0.088 12.2 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EAU86903.2 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EAU86903.2 - 0.096 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EAU86903.2 - 0.1 12.7 0.0 0.43 10.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EAU86903.2 - 0.14 11.5 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain Med8 PF10232.4 EAU86904.2 - 0.00014 21.5 5.8 0.00022 20.8 0.0 2.9 3 0 0 3 3 3 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF572 PF04502.8 EAU86904.2 - 0.00079 18.7 0.2 0.001 18.3 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Nop14 PF04147.7 EAU86904.2 - 0.017 13.0 9.4 0.025 12.4 6.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EAU86904.2 - 0.073 11.1 4.3 0.091 10.7 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EAU86904.2 - 0.13 11.8 3.9 0.18 11.3 2.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF605 PF04652.11 EAU86904.2 - 0.83 8.9 13.4 1.2 8.4 9.3 1.2 1 0 0 1 1 1 0 Vta1 like CobT PF06213.7 EAU86904.2 - 5.4 6.0 14.4 7.8 5.5 10.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT His_Phos_2 PF00328.17 EAU86905.2 - 8.3e-13 48.3 0.0 1.3e-12 47.7 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Adeno_E3_14_5 PF04834.7 EAU86906.2 - 0.15 12.5 1.3 0.75 10.2 0.9 2.2 1 0 0 1 1 1 0 Early E3 14.5 kDa protein DivIC PF04977.10 EAU86908.2 - 0.0084 15.5 0.7 0.13 11.7 0.1 2.3 1 1 1 2 2 2 2 Septum formation initiator DUF4218 PF13960.1 EAU86909.2 - 7.2e-07 28.7 0.0 1.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EAU86909.2 - 7.9e-07 28.3 0.3 2.1e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 MBT PF02820.13 EAU86909.2 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 mbt repeat DUF1258 PF06869.7 EAU86909.2 - 0.079 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) ABC_tran PF00005.22 EAU86911.2 - 2.7e-21 76.2 0.0 4.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU86911.2 - 1.9e-09 37.9 0.0 3.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EAU86911.2 - 1.5e-05 24.3 0.0 0.099 11.8 0.3 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAU86911.2 - 0.00024 20.5 0.2 0.00052 19.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU86911.2 - 0.0011 18.9 0.1 0.0025 17.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EAU86911.2 - 0.0012 18.0 0.0 0.0048 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EAU86911.2 - 0.0039 17.5 0.1 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EAU86911.2 - 0.0043 17.5 0.1 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EAU86911.2 - 0.018 14.2 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAU86911.2 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EAU86911.2 - 0.021 13.4 0.1 0.4 9.2 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MobB PF03205.9 EAU86911.2 - 0.027 14.1 0.4 0.061 13.0 0.3 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EAU86911.2 - 0.037 14.1 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EAU86911.2 - 0.052 13.2 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EAU86911.2 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_13 PF13166.1 EAU86911.2 - 0.067 11.6 0.0 0.099 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAU86911.2 - 0.13 11.9 0.1 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EAU86911.2 - 0.15 12.8 0.2 0.47 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU86911.2 - 0.17 11.7 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Aconitase PF00330.15 EAU86914.2 - 1.5e-179 597.3 0.7 3.1e-179 596.3 0.5 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EAU86914.2 - 2.9e-46 156.8 0.0 5.9e-46 155.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain HMG_box_2 PF09011.5 EAU86918.1 - 1e-10 41.7 17.2 2.7e-06 27.6 3.0 3.1 2 2 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EAU86918.1 - 1.4e-09 38.0 21.3 9.3e-05 22.6 5.4 3.9 2 2 0 2 2 2 2 HMG (high mobility group) box TipAS PF07739.8 EAU86918.1 - 0.091 13.0 6.3 1.1 9.5 1.6 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain PI-PLC-X PF00388.14 EAU86921.2 - 1.2e-06 28.0 0.0 2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF2787 PF10980.3 EAU86921.2 - 0.14 12.0 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2787) ABC_tran PF00005.22 EAU86922.2 - 2.5e-22 79.6 0.0 4.5e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU86922.2 - 1e-08 35.5 0.1 0.0002 21.4 0.0 2.6 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EAU86922.2 - 3.1e-06 26.5 0.1 0.074 12.2 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAU86922.2 - 0.00031 20.2 0.2 0.00081 18.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EAU86922.2 - 0.0032 15.9 0.0 0.013 14.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU86922.2 - 0.0048 16.8 0.2 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAU86922.2 - 0.0052 17.5 0.0 0.023 15.5 0.0 2.3 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 EAU86922.2 - 0.0059 17.0 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ABC_ATPase PF09818.4 EAU86922.2 - 0.018 13.6 0.4 0.065 11.8 0.0 2.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 EAU86922.2 - 0.026 14.8 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAU86922.2 - 0.026 13.9 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAU86922.2 - 0.029 14.7 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EAU86922.2 - 0.029 13.8 0.7 0.32 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 EAU86922.2 - 0.033 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1887 PF09002.6 EAU86922.2 - 0.036 12.4 0.0 0.061 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) MobB PF03205.9 EAU86922.2 - 0.04 13.6 0.5 0.091 12.4 0.3 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EAU86922.2 - 0.078 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU86922.2 - 0.082 12.7 0.1 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU86922.2 - 0.11 12.1 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EAU86922.2 - 0.12 11.8 0.1 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GluR_Homer-bdg PF10606.4 EAU86923.2 - 0.0039 17.0 0.0 0.0088 15.9 0.0 1.5 1 0 0 1 1 1 1 Homer-binding domain of metabotropic glutamate receptor p450 PF00067.17 EAU86925.2 - 1.4e-68 231.5 0.0 2e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIRT PF15099.1 EAU86926.2 - 0.09 12.0 0.9 0.18 11.0 0.2 1.8 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family Phage_Gp23 PF10669.4 EAU86926.2 - 0.33 11.0 4.6 19 5.3 0.1 3.3 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) ETRAMP PF09716.5 EAU86926.2 - 0.35 10.8 3.4 0.99 9.4 1.1 2.5 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Spermine_synth PF01564.12 EAU86927.2 - 7.9e-09 34.8 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EAU86927.2 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU86927.2 - 0.16 12.5 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain IGPS PF00218.16 EAU86928.2 - 1.1e-81 273.6 0.2 1.9e-81 272.8 0.1 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EAU86928.2 - 4e-17 62.4 0.0 9.4e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.14 EAU86928.2 - 5.7e-05 22.6 0.1 0.0004 19.9 0.1 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 EAU86928.2 - 0.0079 15.1 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.16 EAU86928.2 - 0.024 13.5 0.6 0.14 11.0 0.1 2.3 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase DUF2803 PF10972.3 EAU86930.2 - 0.081 12.4 0.0 0.088 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) GMC_oxred_N PF00732.14 EAU86932.2 - 5.3e-59 199.7 0.0 9.4e-59 198.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU86932.2 - 1.1e-32 113.3 0.0 1.9e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAU86932.2 - 2e-07 30.2 0.0 6e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU86932.2 - 3.4e-06 26.9 0.1 5.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAU86932.2 - 8.1e-06 24.9 0.1 4.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EAU86932.2 - 1.4e-05 25.3 0.3 0.015 15.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU86932.2 - 0.00014 20.8 0.2 0.00076 18.4 0.0 2.1 2 1 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EAU86932.2 - 0.0019 18.0 0.0 0.061 13.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU86932.2 - 0.0047 17.0 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU86932.2 - 0.0056 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EAU86932.2 - 0.034 12.7 0.2 0.28 9.7 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase TrkA_N PF02254.13 EAU86932.2 - 0.088 12.8 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 EAU86932.2 - 0.096 11.1 0.1 0.26 9.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EAU86932.2 - 0.11 12.2 0.2 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 EAU86933.2 - 6.3e-63 212.6 0.0 8.4e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU86933.2 - 5.9e-24 84.9 0.0 1.3e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EAU86933.2 - 1.3e-05 24.3 0.0 2.8e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU86933.2 - 2.4e-05 23.4 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAU86933.2 - 5.5e-05 23.1 0.1 0.00022 21.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU86933.2 - 0.00011 21.2 0.3 0.00096 18.1 0.0 2.3 2 1 1 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EAU86933.2 - 0.0051 17.1 0.0 0.079 13.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU86933.2 - 0.0057 15.7 0.0 0.013 14.6 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EAU86933.2 - 0.006 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EAU86933.2 - 0.078 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EAU86933.2 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EAU86933.2 - 0.21 10.0 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein TFIIIC_delta PF12657.2 EAU86934.2 - 1.7e-19 70.2 0.5 5.5e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EAU86934.2 - 7.3e-15 54.6 0.2 7.5e-12 45.0 0.1 2.4 2 0 0 2 2 2 2 Putative zinc-finger of transcription factor IIIC complex PAP2 PF01569.16 EAU86935.2 - 9.7e-16 57.6 5.7 1.3e-15 57.2 3.6 1.4 1 1 0 1 1 1 1 PAP2 superfamily Peptidase_M54 PF07998.6 EAU86935.2 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF3082 PF11282.3 EAU86935.2 - 0.44 10.6 0.0 0.44 10.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3082) Polysacc_synt_C PF14667.1 EAU86935.2 - 1.6 8.5 11.5 0.06 13.1 3.7 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain COX14 PF14880.1 EAU86935.2 - 2 8.1 4.4 3.7 7.2 1.6 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Pirin_C PF05726.8 EAU86936.2 - 0.22 11.6 4.2 51 4.0 0.0 4.4 1 1 4 5 5 5 0 Pirin C-terminal cupin domain DUF1413 PF07205.6 EAU86938.1 - 0.054 13.0 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Pkinase PF00069.20 EAU86939.2 - 9.7e-06 24.9 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86939.2 - 0.058 12.4 0.0 0.17 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 EAU86940.2 - 5e-06 25.8 0.0 8e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86940.2 - 0.012 14.7 0.0 0.075 12.0 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU86942.2 - 5.9e-06 25.6 0.0 8.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86942.2 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU86942.2 - 0.0088 15.7 0.1 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family MAP65_ASE1 PF03999.7 EAU86943.2 - 8.4e-63 212.9 10.5 4.7e-61 207.1 2.2 2.5 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Ala_racemase_N PF01168.15 EAU86943.2 - 0.0029 17.2 0.4 0.008 15.7 0.1 1.9 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain CHZ PF09649.5 EAU86945.2 - 0.15 11.3 0.4 0.36 10.0 0.3 1.6 1 0 0 1 1 1 0 Histone chaperone domain CHZ Parathyroid PF01279.12 EAU86946.2 - 4.9 7.8 8.7 0.64 10.6 1.1 2.6 2 0 0 2 2 2 0 Parathyroid hormone family F-box-like PF12937.2 EAU86948.2 - 2.9e-08 33.3 1.4 6.1e-08 32.2 0.9 1.6 1 0 0 1 1 1 1 F-box-like AAA PF00004.24 EAU86949.2 - 9e-20 71.2 0.0 1.7e-09 37.9 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU86949.2 - 0.00056 20.7 0.0 0.0014 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAU86949.2 - 0.0013 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAU86949.2 - 0.0019 17.8 0.0 0.0066 16.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EAU86949.2 - 0.0028 17.6 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EAU86949.2 - 0.0057 15.4 0.0 0.0084 14.8 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus BCS1_N PF08740.6 EAU86949.2 - 0.018 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 BCS1 N terminal AAA_11 PF13086.1 EAU86949.2 - 0.03 13.9 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAU86949.2 - 0.043 13.5 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EAU86949.2 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAU86949.2 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAU86949.2 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tbf5 PF06331.7 EAU86950.1 - 1.3e-22 79.2 0.2 1.4e-22 79.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Rib_5-P_isom_A PF06026.9 EAU86951.1 - 1.4e-55 187.2 0.0 1.8e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) EPSP_synthase PF00275.15 EAU86952.2 - 2.6e-111 372.0 0.0 4.1e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EAU86952.2 - 8.2e-99 329.7 0.0 2e-98 328.4 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EAU86952.2 - 2.1e-60 204.1 0.0 3.6e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EAU86952.2 - 1.2e-29 103.2 0.0 1.2e-28 99.9 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EAU86952.2 - 6.7e-25 86.9 0.0 5.1e-24 84.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EAU86952.2 - 6.4e-12 45.7 0.0 2e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EAU86952.2 - 3.6e-07 29.7 0.0 8e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EAU86952.2 - 0.00063 20.5 0.0 0.0018 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU86952.2 - 0.069 13.4 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EAU86953.2 - 0.00013 21.2 0.0 0.00071 18.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86953.2 - 0.0007 18.7 0.1 0.0013 17.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Lactonase PF10282.4 EAU86955.1 - 4.8e-16 58.7 0.1 9e-16 57.8 0.1 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 EAU86956.1 - 5e-10 38.9 0.1 3.5e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Dioxygenase VWA_2 PF13519.1 EAU86957.1 - 5.6e-14 52.6 0.0 1.2e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 EAU86957.1 - 3.3e-06 26.2 0.0 7.5e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A VWA PF00092.23 EAU86957.1 - 4.8e-06 26.4 0.0 9.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.13 EAU86957.1 - 0.071 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Integrin, beta chain Pkinase_Tyr PF07714.12 EAU86958.2 - 0.0022 17.1 0.3 0.0057 15.7 0.1 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EAU86958.2 - 0.027 13.5 1.7 0.058 12.5 0.4 1.8 1 1 1 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 EAU86959.2 - 4.5e-05 22.6 0.0 7.6e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU86959.2 - 7.1e-05 22.0 0.0 9.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Gag_p24 PF00607.15 EAU86961.2 - 0.064 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) TPR_11 PF13414.1 EAU86965.1 - 2.6e-21 75.0 1.8 9.5e-16 57.2 0.2 2.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAU86965.1 - 3.3e-12 45.3 2.2 0.00034 20.3 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAU86965.1 - 3.5e-12 45.3 0.5 0.0027 17.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAU86965.1 - 4.7e-05 22.8 0.4 0.0098 15.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU86965.1 - 0.00018 22.0 2.3 0.11 13.1 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU86965.1 - 0.0017 18.2 3.3 0.008 16.0 0.3 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU86965.1 - 0.0069 16.9 0.5 10 7.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.13 EAU86965.1 - 0.0091 15.8 1.9 0.044 13.6 0.1 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 EAU86965.1 - 0.011 15.8 1.4 4.7 7.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec8_exocyst PF04048.9 EAU86965.1 - 0.051 13.2 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain TPR_7 PF13176.1 EAU86965.1 - 0.13 12.0 0.2 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Nrap PF03813.9 EAU86967.1 - 1.6e-198 661.5 0.0 1.4e-164 549.1 0.0 2.4 2 1 0 2 2 2 2 Nrap protein APH PF01636.18 EAU86968.2 - 1.1e-09 38.4 0.1 3e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Nop53 PF07767.6 EAU86971.2 - 1.2 8.0 11.2 2 7.2 7.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nucleo_P87 PF07267.6 EAU86972.2 - 0.53 8.9 3.9 0.67 8.5 2.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 EAU86972.2 - 2 6.3 6.7 2.5 6.0 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-RVT PF13966.1 EAU86973.2 - 0.0015 18.7 0.7 0.0031 17.7 0.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF2749 PF10907.3 EAU86974.1 - 0.083 12.7 0.1 2.8 7.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) YIF1 PF03878.10 EAU86975.2 - 2.4e-71 239.6 0.6 3.1e-71 239.3 0.4 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EAU86975.2 - 0.00015 21.3 2.2 0.00029 20.3 1.5 1.5 1 0 0 1 1 1 1 Yip1 domain Mo25 PF08569.6 EAU86979.2 - 3.8e-124 414.0 2.2 4.3e-124 413.9 1.5 1.0 1 0 0 1 1 1 1 Mo25-like RhoGEF PF00621.15 EAU86979.2 - 0.046 13.5 2.9 0.44 10.4 2.0 2.3 1 1 0 1 1 1 0 RhoGEF domain Pyr_redox PF00070.22 EAU86980.1 - 1.1e-12 48.2 0.0 1.5e-10 41.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU86980.1 - 1.4e-11 44.6 0.0 2.9e-05 24.0 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU86980.1 - 1.6e-08 34.8 0.0 2.3e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAU86980.1 - 1.5e-06 27.4 0.2 0.34 9.7 0.0 3.9 3 1 1 4 4 4 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 EAU86980.1 - 5.3e-06 26.2 0.7 0.69 9.6 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.19 EAU86980.1 - 0.0024 16.8 12.2 0.3 9.9 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EAU86980.1 - 0.0029 16.5 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EAU86980.1 - 0.0036 15.8 0.5 0.39 9.1 0.0 3.2 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_7 PF13241.1 EAU86980.1 - 0.0081 16.4 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 EAU86980.1 - 0.009 14.6 1.6 0.59 8.7 0.0 3.2 4 0 0 4 4 4 1 Tryptophan halogenase TrkA_N PF02254.13 EAU86980.1 - 0.0094 15.9 0.2 2.6 8.0 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain GIDA PF01134.17 EAU86980.1 - 0.012 14.4 0.7 25 3.5 0.1 3.5 4 1 0 4 4 4 0 Glucose inhibited division protein A SnoaL_2 PF12680.2 EAU86980.1 - 0.02 15.3 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain Thi4 PF01946.12 EAU86980.1 - 0.044 12.8 0.0 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EAU86980.1 - 0.37 9.8 1.1 6.9 5.6 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_61 PF03443.9 EAU86984.1 - 5.8e-50 170.1 0.0 7.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PAT1 PF09770.4 EAU86984.1 - 6.9 4.7 7.9 8.8 4.4 5.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pyr_redox_2 PF07992.9 EAU86985.1 - 1.9e-18 67.0 0.4 1.5e-09 38.0 0.0 3.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU86985.1 - 1.8e-16 60.3 0.1 5.3e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU86985.1 - 2.2e-09 36.7 1.5 0.0039 16.1 0.0 4.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EAU86985.1 - 8.9e-07 29.1 0.0 0.00034 20.7 0.0 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU86985.1 - 5.2e-06 26.3 0.8 0.63 9.7 0.0 3.5 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EAU86985.1 - 6.3e-06 25.3 0.0 0.32 9.8 0.0 3.7 3 1 1 4 4 4 2 Lycopene cyclase protein Trp_halogenase PF04820.9 EAU86985.1 - 7.8e-05 21.4 0.7 0.054 12.1 0.0 3.5 4 0 0 4 4 4 1 Tryptophan halogenase TrkA_N PF02254.13 EAU86985.1 - 0.00027 20.9 0.1 0.12 12.3 0.0 2.7 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 EAU86985.1 - 0.00036 20.7 0.5 0.026 14.7 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EAU86985.1 - 0.0024 16.9 0.1 0.8 8.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EAU86985.1 - 0.0084 16.1 0.2 0.4 10.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EAU86985.1 - 0.027 13.3 0.6 3.1 6.5 0.0 3.0 4 0 0 4 4 4 0 Glucose inhibited division protein A K_oxygenase PF13434.1 EAU86985.1 - 0.043 12.7 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EAU86985.1 - 0.071 11.5 2.1 16 3.8 0.0 3.8 3 1 1 4 4 4 0 HI0933-like protein Lysine_decarbox PF03641.9 EAU86985.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Possible lysine decarboxylase F-box-like PF12937.2 EAU86986.1 - 1.1e-06 28.2 0.2 3.4e-06 26.6 0.2 2.0 1 0 0 1 1 1 1 F-box-like IncA PF04156.9 EAU86986.1 - 0.0098 15.5 2.7 0.017 14.7 1.9 1.3 1 0 0 1 1 1 1 IncA protein Pro-rich PF15240.1 EAU86990.2 - 8.5e-05 22.7 9.4 8.5e-05 22.7 6.5 2.5 2 0 0 2 2 2 1 Proline-rich DUF605 PF04652.11 EAU86990.2 - 0.00089 18.7 22.7 0.042 13.2 9.4 2.2 2 0 0 2 2 2 2 Vta1 like Cauli_VI PF01693.11 EAU86991.2 - 5.1e-08 32.8 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin LRR_8 PF13855.1 EAU86994.1 - 0.031 14.0 0.5 5.6 6.7 0.0 3.4 2 1 0 2 2 2 0 Leucine rich repeat FmdA_AmdA PF03069.10 EAU86994.1 - 0.12 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Acetamidase/Formamidase family LRR_8 PF13855.1 EAU86995.2 - 0.0068 16.1 4.2 9.3 6.0 0.0 4.9 4 1 1 5 5 5 3 Leucine rich repeat HSBP1 PF06825.7 EAU86999.2 - 0.01 15.3 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Transposase_mut PF00872.13 EAU87004.2 - 0.032 12.8 0.0 0.055 12.0 0.0 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Na_Ca_ex PF01699.19 EAU87006.1 - 1e-38 132.0 23.1 2.6e-20 72.4 4.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ThiF PF00899.16 EAU87007.2 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family CCDC144C PF14915.1 EAU87009.2 - 0.00051 19.0 6.0 0.00051 19.0 4.2 2.0 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region IncA PF04156.9 EAU87009.2 - 0.0016 18.0 14.4 0.0016 18.0 10.0 2.3 1 1 1 2 2 2 1 IncA protein Tropomyosin PF00261.15 EAU87009.2 - 0.0017 17.5 17.2 0.0021 17.1 11.9 1.1 1 0 0 1 1 1 1 Tropomyosin Tmemb_cc2 PF10267.4 EAU87009.2 - 0.0027 16.3 5.0 0.0034 16.0 3.5 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Rab5-bind PF09311.6 EAU87009.2 - 0.0065 16.3 13.9 0.072 12.9 5.7 2.1 1 1 1 2 2 2 1 Rabaptin-like protein Taxilin PF09728.4 EAU87009.2 - 0.0082 15.2 14.3 0.018 14.1 9.9 1.5 1 1 0 1 1 1 1 Myosin-like coiled-coil protein Laminin_I PF06008.9 EAU87009.2 - 0.021 14.1 4.0 0.021 14.1 1.5 1.7 1 1 1 2 2 2 0 Laminin Domain I DUF16 PF01519.11 EAU87009.2 - 0.028 14.6 8.2 0.046 13.9 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Macoilin PF09726.4 EAU87009.2 - 0.028 12.7 4.9 0.033 12.4 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Baculo_PEP_C PF04513.7 EAU87009.2 - 0.032 14.0 0.1 0.66 9.7 0.1 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EAU87009.2 - 0.034 13.9 19.1 0.55 10.0 13.3 2.1 1 1 0 1 1 1 0 Tropomyosin like CALCOCO1 PF07888.6 EAU87009.2 - 0.039 12.2 12.4 0.047 11.9 8.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MbeD_MobD PF04899.7 EAU87009.2 - 0.043 13.7 0.2 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 MbeD/MobD like CAF-1_p150 PF11600.3 EAU87009.2 - 0.044 13.1 11.9 0.049 13.0 8.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF342 PF03961.8 EAU87009.2 - 0.048 12.0 5.7 0.067 11.5 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Laminin_II PF06009.7 EAU87009.2 - 0.068 12.9 5.9 1.1 9.0 1.3 2.3 1 1 1 2 2 2 0 Laminin Domain II RmuC PF02646.11 EAU87009.2 - 0.069 11.9 5.9 0.55 9.0 1.6 2.1 1 1 1 2 2 2 0 RmuC family COG2 PF06148.6 EAU87009.2 - 0.078 12.8 10.8 0.3 10.9 2.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PspA_IM30 PF04012.7 EAU87009.2 - 0.079 12.3 9.7 2.4 7.4 6.7 2.5 1 1 0 1 1 1 0 PspA/IM30 family Atg14 PF10186.4 EAU87009.2 - 0.086 11.7 5.9 0.12 11.3 4.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 EAU87009.2 - 0.093 12.8 6.0 0.26 11.4 1.1 2.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 EAU87009.2 - 0.13 12.0 10.0 1.2 8.9 7.0 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IFT57 PF10498.4 EAU87009.2 - 0.13 10.9 7.4 0.17 10.6 5.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Halogen_Hydrol PF10112.4 EAU87009.2 - 0.14 11.5 1.1 0.91 8.8 0.1 2.1 1 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Spc7 PF08317.6 EAU87009.2 - 0.16 10.6 11.9 0.2 10.2 8.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Vac_Fusion PF02346.11 EAU87009.2 - 0.19 11.1 9.7 0.22 10.9 1.9 3.1 1 1 2 3 3 3 0 Chordopoxvirus fusion protein GAS PF13851.1 EAU87009.2 - 0.23 10.6 15.1 0.48 9.5 10.4 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding GRA6 PF05084.8 EAU87009.2 - 0.28 10.6 2.1 0.23 10.9 0.4 1.6 1 1 1 2 2 2 0 Granule antigen protein (GRA6) TBPIP PF07106.8 EAU87009.2 - 0.39 10.2 12.8 14 5.1 8.5 2.1 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nup54 PF13874.1 EAU87009.2 - 0.42 10.2 10.0 0.8 9.3 6.0 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.3 EAU87009.2 - 0.47 10.3 12.9 1.3 8.9 3.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HemX PF04375.9 EAU87009.2 - 0.48 8.9 3.2 0.32 9.5 1.0 1.5 1 1 0 1 1 1 0 HemX V_ATPase_I PF01496.14 EAU87009.2 - 0.52 8.1 8.4 0.8 7.4 5.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3782 PF12644.2 EAU87009.2 - 0.56 10.0 7.6 36 4.2 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) DUF883 PF05957.8 EAU87009.2 - 0.57 10.6 3.2 1.1 9.7 1.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.1 EAU87009.2 - 0.62 8.4 5.7 1.3 7.4 3.9 1.4 1 1 0 1 1 1 0 AAA domain ORF6C PF10552.4 EAU87009.2 - 0.65 9.7 11.4 1.3 8.7 0.5 3.4 1 1 3 4 4 4 0 ORF6C domain HSBP1 PF06825.7 EAU87009.2 - 0.87 9.2 10.9 0.14 11.7 2.4 2.8 3 1 1 4 4 2 0 Heat shock factor binding protein 1 Mod_r PF07200.8 EAU87009.2 - 0.89 9.4 10.7 3.3 7.5 3.2 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fzo_mitofusin PF04799.8 EAU87009.2 - 0.9 8.9 7.0 1.1 8.5 0.5 2.1 1 1 1 2 2 2 0 fzo-like conserved region Cluap1 PF10234.4 EAU87009.2 - 0.93 8.6 14.4 1 8.4 2.8 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Ax_dynein_light PF10211.4 EAU87009.2 - 1 9.1 14.5 0.41 10.4 2.6 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Bacillus_HBL PF05791.6 EAU87009.2 - 1 8.7 3.4 9.5 5.5 0.3 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Matrilin_ccoil PF10393.4 EAU87009.2 - 1.2 8.5 10.8 0.68 9.3 0.2 3.6 2 1 2 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin ATG16 PF08614.6 EAU87009.2 - 1.3 8.7 14.8 12 5.6 10.3 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2730 PF10805.3 EAU87009.2 - 1.5 8.5 8.6 12 5.6 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF1664 PF07889.7 EAU87009.2 - 1.5 8.5 8.5 3.5 7.4 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.8 EAU87009.2 - 1.5 7.7 7.1 4.9 6.1 3.9 1.9 1 1 1 2 2 2 0 TMPIT-like protein Prefoldin PF02996.12 EAU87009.2 - 1.6 8.3 7.1 3.5 7.2 0.8 2.6 2 1 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EAU87009.2 - 2 7.9 10.6 6.3 6.3 0.1 3.3 1 1 2 3 3 3 0 Septum formation initiator Fib_alpha PF08702.5 EAU87009.2 - 2 8.4 5.9 9.2 6.3 0.2 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EAU87009.2 - 2.1 7.9 11.1 10 5.7 7.4 2.0 1 1 0 1 1 1 0 Mnd1 family bZIP_1 PF00170.16 EAU87009.2 - 2.2 8.3 11.5 3.7 7.5 1.9 3.2 2 1 1 3 3 3 0 bZIP transcription factor EMP24_GP25L PF01105.19 EAU87009.2 - 2.2 7.9 7.8 3.3 7.3 0.4 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Spectrin PF00435.16 EAU87009.2 - 2.6 8.3 11.1 35 4.7 6.9 2.2 1 1 1 2 2 2 0 Spectrin repeat Cauli_AT PF03233.8 EAU87009.2 - 4.2 7.0 8.6 6.1 6.5 1.5 2.6 1 1 1 2 2 2 0 Aphid transmission protein Seryl_tRNA_N PF02403.17 EAU87009.2 - 5.3 7.0 14.2 6.8 6.7 3.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.1 EAU87009.2 - 7.4 6.5 19.2 2 8.3 5.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMCO5 PF14992.1 EAU87009.2 - 8.4 5.4 15.2 24 3.9 10.6 1.3 1 1 0 1 1 1 0 TMCO5 family DUF972 PF06156.8 EAU87009.2 - 8.8 6.7 12.6 1.1e+02 3.2 4.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) GMC_oxred_C PF05199.8 EAU87010.1 - 4.6e-34 117.7 0.0 7.4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EAU87010.1 - 1.9e-25 89.6 0.0 2.7e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EAU87011.2 - 2.6e-34 118.7 0.0 2.8e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EAU87011.2 - 1.3e-05 24.3 0.0 1.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EAU87011.2 - 1.5e-05 24.0 0.1 3.8e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU87011.2 - 3.9e-05 23.5 0.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU87011.2 - 0.00092 18.1 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EAU87011.2 - 0.0089 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU87011.2 - 0.0094 15.7 0.1 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding TrkA_N PF02254.13 EAU87011.2 - 0.019 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EAU87011.2 - 0.033 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EAU87011.2 - 0.1 11.1 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EAU87011.2 - 0.14 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Abhydrolase_5 PF12695.2 EAU87012.2 - 3.6e-22 78.6 0.0 5.9e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU87012.2 - 4.5e-17 62.7 0.0 5.7e-15 55.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAU87012.2 - 1.2e-05 24.8 0.0 0.16 11.4 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EAU87012.2 - 6.9e-05 22.4 0.0 0.0012 18.4 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EAU87012.2 - 0.00016 21.4 0.0 0.016 14.9 0.0 2.1 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EAU87012.2 - 0.00025 20.4 0.0 0.4 9.9 0.0 2.7 4 0 0 4 4 4 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EAU87012.2 - 0.0052 16.2 0.0 2.3 7.5 0.0 2.1 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EAU87012.2 - 0.0054 15.2 0.5 0.71 8.3 0.1 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EAU87012.2 - 0.024 13.8 0.0 0.18 11.0 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.8 EAU87012.2 - 0.029 13.7 0.0 0.068 12.6 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 EAU87012.2 - 0.099 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Methyltransf_2 PF00891.13 EAU87013.2 - 1.3e-16 60.5 0.0 2.1e-14 53.3 0.0 2.4 2 0 0 2 2 2 2 O-methyltransferase FHIPEP PF00771.15 EAU87014.2 - 0.034 12.4 0.1 0.036 12.3 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Mnd1 PF03962.10 EAU87015.1 - 0.00049 19.8 8.4 0.00049 19.8 5.8 2.4 1 1 1 2 2 2 1 Mnd1 family Apolipoprotein PF01442.13 EAU87015.1 - 0.0056 16.2 22.5 0.013 15.0 7.7 2.6 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain F_actin_bind PF08919.5 EAU87015.1 - 0.062 13.0 2.5 0.2 11.3 1.7 1.9 1 0 0 1 1 1 0 F-actin binding Gp49 PF05973.9 EAU87015.1 - 0.075 13.0 2.5 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) DUF2587 PF10759.4 EAU87015.1 - 0.077 12.3 4.0 0.075 12.4 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2587) Nbs1_C PF08599.5 EAU87015.1 - 0.11 12.4 0.1 0.11 12.4 0.0 2.6 3 0 0 3 3 3 0 DNA damage repair protein Nbs1 Fib_alpha PF08702.5 EAU87015.1 - 0.14 12.3 12.7 0.17 11.9 4.8 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GHL13 PF14883.1 EAU87015.1 - 0.14 11.2 4.3 0.083 12.0 0.8 2.1 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 13 Baculo_PEP_C PF04513.7 EAU87015.1 - 0.28 11.0 9.7 4.1 7.2 0.5 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 EAU87015.1 - 0.31 10.3 9.4 0.27 10.5 3.2 2.8 2 2 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF465 PF04325.8 EAU87015.1 - 0.36 10.5 0.2 0.36 10.5 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF465) Mer2 PF09074.5 EAU87015.1 - 0.41 10.5 16.1 3.1 7.6 10.5 2.6 1 1 1 2 2 2 0 Mer2 DUF1993 PF09351.5 EAU87015.1 - 0.42 10.5 4.4 0.22 11.4 1.1 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF1993) Ribonuc_2-5A PF06479.7 EAU87015.1 - 0.49 10.2 7.2 0.11 12.3 0.6 2.6 1 1 2 3 3 3 0 Ribonuclease 2-5A Syntaxin_2 PF14523.1 EAU87015.1 - 0.75 9.8 12.6 0.066 13.2 3.8 2.6 2 1 1 3 3 3 0 Syntaxin-like protein FadA PF09403.5 EAU87015.1 - 1.4 8.9 19.7 1.4 8.9 5.1 2.8 1 1 2 3 3 3 0 Adhesion protein FadA Nup88 PF10168.4 EAU87015.1 - 1.4 6.6 13.6 0.029 12.2 3.6 1.9 2 0 0 2 2 2 0 Nuclear pore component YlqD PF11068.3 EAU87015.1 - 1.7 8.6 12.6 0.14 12.1 2.2 3.0 1 1 2 3 3 3 0 YlqD protein DegQ PF08181.6 EAU87015.1 - 1.9 8.2 7.2 6.8 6.4 0.1 3.5 3 1 0 3 3 3 0 DegQ (SacQ) family DUF2317 PF10079.4 EAU87015.1 - 2.3 6.7 13.2 0.74 8.3 6.6 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) TetR_C_6 PF13977.1 EAU87015.1 - 3.5 7.6 11.2 0.84 9.6 0.5 3.6 2 2 2 4 4 4 0 Bacterial transcriptional repressor TBPIP PF07106.8 EAU87015.1 - 3.5 7.1 16.7 0.81 9.2 7.6 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TipAS PF07739.8 EAU87015.1 - 4.1 7.7 11.7 4 7.7 0.7 2.9 1 1 1 3 3 3 0 TipAS antibiotic-recognition domain GvpK PF05121.7 EAU87015.1 - 4.4 7.1 19.2 3.1 7.6 2.2 3.7 2 2 2 4 4 4 0 Gas vesicle protein K DUF2115 PF09888.4 EAU87015.1 - 5 7.2 6.9 4.4 7.3 1.8 2.5 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) DUF1664 PF07889.7 EAU87015.1 - 5.9 6.6 13.0 4.3 7.1 0.1 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) PspA_IM30 PF04012.7 EAU87016.2 - 0.035 13.4 9.6 0.15 11.4 6.6 1.8 1 1 0 1 1 1 0 PspA/IM30 family CtIP_N PF10482.4 EAU87016.2 - 0.036 13.8 8.9 0.067 12.9 3.8 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Fib_alpha PF08702.5 EAU87016.2 - 0.038 14.1 5.6 0.077 13.1 0.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EAU87016.2 - 0.1 12.4 1.8 5.1 6.9 0.4 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDC37_N PF03234.9 EAU87016.2 - 0.13 12.5 9.3 0.23 11.7 5.6 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF1451 PF07295.6 EAU87016.2 - 0.37 10.5 3.9 0.46 10.2 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) Exonuc_VII_L PF02601.10 EAU87016.2 - 0.4 9.8 7.8 0.56 9.3 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Apolipoprotein PF01442.13 EAU87016.2 - 0.45 9.9 7.6 0.98 8.8 5.2 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain V_ATPase_I PF01496.14 EAU87016.2 - 2.5 5.8 4.2 3.8 5.2 2.1 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Rabaptin PF03528.10 EAU87016.2 - 3.6 7.5 7.5 4.3 7.3 2.1 2.5 1 1 1 2 2 2 0 Rabaptin CENP-H PF05837.7 EAU87016.2 - 4.7 7.4 10.9 5.9 7.1 3.3 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Sucrose_synth PF00862.14 EAU87018.2 - 0.027 12.4 0.0 0.04 11.8 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase GMC_oxred_N PF00732.14 EAU87019.2 - 3.5e-39 134.7 0.0 1.5e-37 129.4 0.0 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87019.2 - 2.4e-32 112.2 0.0 4.7e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAU87019.2 - 2.2e-07 30.1 0.0 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EAU87019.2 - 6.4e-05 22.0 0.0 9.9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAU87019.2 - 0.00014 21.8 0.3 0.00058 19.8 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU87019.2 - 0.00017 20.6 0.1 0.0009 18.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAU87019.2 - 0.016 14.9 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EAU87019.2 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU87019.2 - 0.099 13.0 0.1 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EAU87019.2 - 0.1 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EAU87019.2 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Metallophos PF00149.23 EAU87021.2 - 2.8e-40 137.8 0.0 4e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF658 PF04936.7 EAU87021.2 - 0.15 11.9 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF658) Skp1_POZ PF03931.10 EAU87022.2 - 5.1e-05 23.2 0.0 0.00021 21.3 0.0 1.9 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain F-box-like PF12937.2 EAU87029.1 - 7e-10 38.4 0.3 2e-09 36.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU87029.1 - 0.0058 16.2 0.1 0.56 9.9 0.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EAU87029.1 - 0.046 13.3 0.3 0.17 11.5 0.2 2.0 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) Curto_V3 PF07436.6 EAU87029.1 - 0.075 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Curtovirus V3 protein F-box-like PF12937.2 EAU87030.1 - 9.5e-08 31.6 0.4 2e-07 30.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU87030.1 - 0.00045 19.7 1.3 0.0046 16.5 0.9 2.4 1 1 0 1 1 1 1 F-box domain Band_7 PF01145.20 EAU87031.1 - 1.7e-25 89.9 0.1 1.7e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EAU87031.1 - 1.7e-05 24.4 0.0 4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 SPFH domain-Band 7 family Glyco_hydro_47 PF01532.15 EAU87032.2 - 6.2e-127 423.9 0.0 8.8e-127 423.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 F-box-like PF12937.2 EAU87035.1 - 0.0012 18.5 0.1 0.0036 16.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like Sld5 PF05916.6 EAU87036.1 - 0.002 18.3 0.0 0.0047 17.1 0.0 1.7 1 1 0 1 1 1 1 GINS complex protein MARVEL PF01284.18 EAU87042.1 - 0.0089 15.8 8.9 0.26 11.0 6.2 2.3 1 1 0 1 1 1 1 Membrane-associating domain ABC2_membrane PF01061.19 EAU87042.1 - 0.077 12.1 7.4 0.14 11.2 0.5 2.4 2 1 0 2 2 2 0 ABC-2 type transporter TM_helix PF05552.7 EAU87042.1 - 0.17 11.5 1.7 0.31 10.7 0.1 2.2 2 1 0 2 2 2 0 Conserved TM helix RseC_MucC PF04246.7 EAU87042.1 - 0.46 10.0 6.5 1.5 8.3 0.6 2.6 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PRA1 PF03208.14 EAU87042.1 - 0.47 9.7 10.8 0.5 9.6 5.7 2.3 2 1 0 2 2 2 0 PRA1 family protein F-box-like PF12937.2 EAU87043.2 - 0.11 12.2 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like Med6 PF04934.9 EAU87044.2 - 0.15 11.5 0.1 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 MED6 mediator sub complex component Daxx PF03344.10 EAU87044.2 - 1.3 7.3 6.2 1.6 7.0 4.3 1.1 1 0 0 1 1 1 0 Daxx Family MOZ_SAS PF01853.13 EAU87047.2 - 0.013 14.7 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 MOZ/SAS family HSBP1 PF06825.7 EAU87048.2 - 0.00091 18.7 2.8 0.77 9.3 0.0 4.1 3 1 0 3 3 3 2 Heat shock factor binding protein 1 HlyD PF00529.15 EAU87048.2 - 0.0028 16.9 0.2 0.0052 16.1 0.1 1.4 1 0 0 1 1 1 1 HlyD family secretion protein SlyX PF04102.7 EAU87048.2 - 0.015 15.6 5.2 31 5.0 0.1 4.1 3 2 1 4 4 4 0 SlyX BLOC1_2 PF10046.4 EAU87048.2 - 0.034 14.2 1.8 13 5.9 0.0 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prefoldin_2 PF01920.15 EAU87048.2 - 0.062 13.0 3.3 13 5.5 0.2 3.4 2 1 1 3 3 3 0 Prefoldin subunit Fib_alpha PF08702.5 EAU87048.2 - 0.22 11.6 2.0 3.2 7.8 0.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.6 EAU87048.2 - 0.38 10.5 5.7 3.5 7.4 0.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1515) FlaC_arch PF05377.6 EAU87048.2 - 4.8 7.1 9.9 13 5.8 1.1 3.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) AAA_22 PF13401.1 EAU87049.2 - 1.4e-06 28.4 0.1 9e-06 25.8 0.0 2.3 2 1 0 3 3 3 1 AAA domain NACHT PF05729.7 EAU87049.2 - 2.2e-06 27.4 0.0 7.1e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU87049.2 - 0.0014 18.6 0.0 0.0099 15.8 0.0 2.3 2 1 2 4 4 4 1 AAA ATPase domain NB-ARC PF00931.17 EAU87049.2 - 0.0081 15.0 0.0 0.03 13.1 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 EAU87049.2 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EAU87049.2 - 0.028 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EAU87049.2 - 0.04 13.8 0.0 0.13 12.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EAU87049.2 - 0.12 11.5 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 EAU87049.2 - 0.14 11.7 0.2 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EAU87049.2 - 0.18 12.0 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Ank_2 PF12796.2 EAU87050.2 - 5.3e-69 228.6 11.1 3.5e-10 40.0 0.1 9.4 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU87050.2 - 2.4e-54 180.1 33.0 6.3e-07 29.4 0.1 12.0 5 4 6 12 12 12 10 Ankyrin repeats (many copies) Ank PF00023.25 EAU87050.2 - 5e-48 158.6 27.3 1.2e-05 24.8 0.0 14.7 16 0 0 16 16 16 11 Ankyrin repeat Ank_4 PF13637.1 EAU87050.2 - 1.5e-47 159.1 25.4 8.2e-08 32.5 0.0 14.2 3 3 11 14 14 14 13 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU87050.2 - 6.8e-39 128.0 6.3 0.00055 19.9 0.0 15.0 16 0 0 16 16 16 9 Ankyrin repeat Glyco_hydro_61 PF03443.9 EAU87051.1 - 7.8e-55 186.0 0.0 1.1e-54 185.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-MYND PF01753.13 EAU87052.2 - 5.1e-11 42.2 7.1 1.4e-10 40.8 4.9 1.8 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU87052.2 - 0.14 11.4 3.3 0.32 10.3 2.3 1.5 1 0 0 1 1 1 0 Life-span regulatory factor p450 PF00067.17 EAU87054.2 - 2.8e-64 217.3 0.0 1.1e-63 215.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Pre-SET PF05033.11 EAU87055.2 - 3e-19 69.1 2.2 3e-19 69.1 1.5 2.3 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.23 EAU87055.2 - 1.5e-13 51.3 0.5 1.5e-13 51.3 0.3 3.1 3 1 0 3 3 3 1 SET domain UQ_con PF00179.21 EAU87056.2 - 3e-20 72.1 0.0 5.1e-20 71.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme PRCC PF10253.4 EAU87056.2 - 4.4 7.9 7.9 0.91 10.1 2.1 2.0 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Ank_2 PF12796.2 EAU87063.2 - 2.2e-24 85.5 7.6 2.2e-12 47.1 0.1 4.9 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU87063.2 - 6.4e-20 70.7 2.2 7.3e-08 32.4 0.1 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU87063.2 - 4.5e-15 55.7 6.1 2.7e-07 30.9 0.1 5.7 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EAU87063.2 - 1.5e-13 49.8 5.2 0.0024 17.5 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.1 EAU87063.2 - 1.2e-11 43.6 2.1 0.023 14.8 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.7 EAU87063.2 - 1.3e-05 24.9 0.3 9.2e-05 22.1 0.1 2.4 1 1 1 2 2 2 1 NACHT domain AAA_22 PF13401.1 EAU87063.2 - 0.0012 19.0 0.1 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain REV PF00424.13 EAU87064.2 - 0.0016 18.2 0.4 0.0037 17.1 0.2 1.5 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) OPT PF03169.10 EAU87065.2 - 1.1e-191 638.5 53.6 1.2e-191 638.3 37.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Beta_helix PF13229.1 EAU87066.1 - 0.0021 17.8 23.6 0.0021 17.8 16.3 2.4 1 1 1 2 2 2 2 Right handed beta helix region Ank_2 PF12796.2 EAU87067.2 - 5.1e-63 209.4 44.4 3.2e-15 56.2 0.1 11.0 1 1 10 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU87067.2 - 1.6e-55 184.5 30.3 3.3e-08 33.8 0.1 15.6 5 3 11 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU87067.2 - 1.5e-54 180.7 40.9 1.8e-09 37.4 0.3 13.5 7 3 7 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.25 EAU87067.2 - 1.1e-48 160.6 32.1 0.0033 17.1 0.1 16.3 16 0 0 16 16 16 11 Ankyrin repeat Ank_3 PF13606.1 EAU87067.2 - 7.8e-41 134.0 17.8 0.005 16.9 0.0 16.4 17 0 0 17 17 16 9 Ankyrin repeat NACHT PF05729.7 EAU87067.2 - 1.5e-05 24.6 0.0 4.5e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU87067.2 - 2.7e-05 24.2 0.3 0.00033 20.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU87067.2 - 7.7e-05 22.8 0.2 0.00099 19.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF3126 PF11324.3 EAU87067.2 - 0.0012 18.4 0.1 18 5.0 0.0 5.6 7 0 0 7 7 6 0 Protein of unknown function (DUF3126) Cut8_M PF14483.1 EAU87067.2 - 0.03 14.1 0.7 2.9 7.7 0.0 3.7 3 0 0 3 3 3 0 Cut8 dimerisation domain DUF2075 PF09848.4 EAU87067.2 - 0.086 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Activator-TraM PF11657.3 EAU87067.2 - 0.31 10.4 4.9 0.15 11.5 1.2 2.0 2 0 0 2 2 2 0 Transcriptional activator TraM Ank_2 PF12796.2 EAU87068.2 - 1.4e-54 182.3 12.0 9e-11 41.9 0.0 8.2 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EAU87068.2 - 3.2e-48 159.1 9.2 1.1e-06 28.0 0.0 12.5 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 EAU87068.2 - 2.9e-44 148.0 20.6 7.7e-08 32.3 1.6 10.7 5 4 5 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU87068.2 - 8.9e-37 124.8 17.4 7.6e-09 35.8 0.1 11.2 3 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU87068.2 - 1.4e-29 99.1 3.4 0.0067 16.5 0.0 11.6 11 0 0 11 11 11 8 Ankyrin repeat DUF3126 PF11324.3 EAU87068.2 - 0.0016 18.1 0.0 6.5 6.4 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3126) CorA PF01544.13 EAU87069.2 - 1.4e-13 50.6 8.4 5.5e-13 48.5 5.8 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CTP_transf_2 PF01467.21 EAU87069.2 - 0.11 12.5 0.3 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 Cytidylyltransferase DUF763 PF05559.6 EAU87069.2 - 0.2 10.5 0.7 0.34 9.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) zf-MYND PF01753.13 EAU87070.1 - 2.5e-10 40.0 8.5 5.2e-10 39.0 5.9 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU87070.1 - 0.011 15.0 1.4 0.021 14.0 1.0 1.5 1 0 0 1 1 1 0 Life-span regulatory factor WD40 PF00400.27 EAU87073.2 - 3.1e-06 26.8 8.2 0.046 13.6 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 EAU87073.2 - 0.053 13.2 1.3 14 5.5 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-C3HC4 PF00097.20 EAU87075.2 - 4e-07 29.5 4.0 8.3e-07 28.5 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU87075.2 - 2.6e-06 27.3 5.2 4e-06 26.7 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU87075.2 - 1.9e-05 24.2 9.1 0.00032 20.2 6.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU87075.2 - 2.9e-05 23.7 4.0 0.0001 22.0 2.8 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU87075.2 - 4.1e-05 23.3 2.6 0.00017 21.3 0.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DUF1644 PF07800.7 EAU87075.2 - 0.00018 21.4 0.6 0.00037 20.4 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) zf-RING_5 PF14634.1 EAU87075.2 - 0.00093 18.8 6.0 0.0024 17.5 1.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAU87075.2 - 0.029 14.0 0.6 0.029 14.0 0.4 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EAU87075.2 - 0.12 11.9 6.0 0.1 12.1 1.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_Tnp_IS91 PF14319.1 EAU87075.2 - 0.28 10.7 4.2 0.19 11.2 0.8 2.0 1 1 1 2 2 2 0 Transposase zinc-binding domain Brr6_like_C_C PF10104.4 EAU87077.1 - 4.6e-25 87.6 0.0 5.2e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Frag1 PF10277.4 EAU87080.2 - 0.021 14.2 0.6 0.027 13.9 0.4 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family YjgP_YjgQ PF03739.9 EAU87080.2 - 0.024 13.3 0.1 0.027 13.2 0.1 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Ca_hom_mod PF14798.1 EAU87080.2 - 0.029 13.3 0.6 0.038 12.9 0.4 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF3522 PF12036.3 EAU87080.2 - 0.079 12.7 0.9 0.094 12.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF4233 PF14017.1 EAU87080.2 - 0.099 12.5 4.0 0.14 12.1 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) DUF962 PF06127.6 EAU87081.1 - 0.67 9.8 4.5 0.37 10.6 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF962) Lig_chan PF00060.21 EAU87084.1 - 1.4 8.6 3.7 2 8.1 0.4 2.5 2 1 0 2 2 2 0 Ligand-gated ion channel Glyco_hydro_47 PF01532.15 EAU87085.1 - 1.6e-127 425.9 0.1 1.8e-127 425.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Isochorismatase PF00857.15 EAU87087.2 - 2e-20 73.4 0.1 3.5e-20 72.6 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family F-box-like PF12937.2 EAU87088.2 - 7.9e-08 31.9 3.7 1.7e-07 30.8 2.5 1.6 1 0 0 1 1 1 1 F-box-like Isochorismatase PF00857.15 EAU87089.1 - 2.8e-19 69.7 0.2 5.4e-19 68.7 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family Asp-Al_Ex PF06826.7 EAU87090.2 - 0.015 14.7 0.3 0.035 13.5 0.2 1.6 1 0 0 1 1 1 0 Predicted Permease Membrane Region DUF3671 PF12420.3 EAU87090.2 - 0.058 13.3 0.9 0.17 11.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function UPF0016 PF01169.14 EAU87091.1 - 1.1e-44 150.4 20.3 7.4e-23 80.4 4.2 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 EAU87091.1 - 0.0023 17.3 5.2 0.0028 17.1 0.0 2.5 2 1 0 2 2 2 1 Integral membrane protein TerC family DUF2208 PF09973.4 EAU87091.1 - 0.019 14.2 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) TauE PF01925.14 EAU87091.1 - 0.065 12.6 16.5 0.87 8.9 11.4 2.0 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF872 PF05915.7 EAU87091.1 - 0.15 11.9 0.7 1.6 8.5 0.0 2.7 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF3995 PF13160.1 EAU87091.1 - 0.52 10.3 6.9 1.5 8.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF204 PF02659.10 EAU87091.1 - 1.2 9.2 13.9 1.3 9.1 1.5 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF p450 PF00067.17 EAU87092.1 - 3.7e-66 223.5 0.0 4.5e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Metallophos_2 PF12850.2 EAU87095.2 - 6.6e-20 71.5 0.1 8.2e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAU87095.2 - 0.00023 20.6 2.9 0.03 13.7 0.0 2.4 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase LRR19-TM PF15176.1 EAU87097.1 - 0.29 10.8 3.9 0.4 10.4 0.0 2.9 2 1 2 4 4 4 0 Leucine-rich repeat family 19 TM domain DUF2422 PF10337.4 EAU87098.2 - 9.8e-69 232.3 0.0 1.6e-68 231.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EAU87098.2 - 1.9e-56 191.2 0.0 2.8e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EAU87098.2 - 2.1e-07 30.9 16.1 2.1e-07 30.9 11.2 3.6 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 EAU87098.2 - 0.066 11.8 7.3 0.75 8.3 4.7 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF515 PF04415.7 EAU87098.2 - 1.5 6.9 3.5 2.3 6.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.4 EAU87098.2 - 2.6 7.4 10.9 4.9 6.5 7.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NB PF04159.8 EAU87099.2 - 0.074 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 NB glycoprotein SHR3_chaperone PF08229.6 EAU87100.1 - 0.52 9.2 2.7 4.2 6.2 0.1 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 DUF1218 PF06749.7 EAU87100.1 - 2.6 8.5 6.8 15 6.1 4.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1218) DEAD PF00270.24 EAU87101.1 - 4.6e-21 75.0 0.0 9.6e-20 70.7 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU87101.1 - 2.9e-09 36.6 0.0 9.5e-09 35.0 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU87101.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SHR3_chaperone PF08229.6 EAU87105.2 - 0.19 10.6 4.3 2.1 7.2 0.3 2.4 2 0 0 2 2 2 0 ER membrane protein SH3 FMO-like PF00743.14 EAU87107.2 - 2.9e-30 104.9 0.0 2.9e-19 68.6 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EAU87107.2 - 1.2e-13 51.5 0.6 2e-12 47.6 0.4 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU87107.2 - 1.6e-09 37.9 0.0 0.00071 19.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU87107.2 - 1.3e-07 31.5 0.0 4.5e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EAU87107.2 - 2.4e-07 29.9 0.1 3.2e-06 26.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EAU87107.2 - 0.0022 16.9 0.2 0.009 14.9 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EAU87107.2 - 0.0032 16.6 0.0 0.0082 15.2 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EAU87107.2 - 0.011 15.4 0.8 0.1 12.3 0.6 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EAU87107.2 - 0.012 16.0 0.0 6.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EAU87107.2 - 0.024 14.4 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.12 EAU87107.2 - 0.031 13.3 0.0 0.091 11.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Peptidase_C54 PF03416.14 EAU87108.2 - 1.1e-80 270.8 0.0 4.7e-69 232.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase family C54 Peptidase_M43 PF05572.8 EAU87110.2 - 6e-18 64.9 0.0 1.1e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EAU87110.2 - 0.0011 19.1 1.1 0.0021 18.1 0.8 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU87110.2 - 0.0013 18.2 0.1 0.0037 16.8 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAU87110.2 - 0.0084 16.6 1.3 0.029 14.9 0.9 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU87110.2 - 0.009 15.9 0.2 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 UCH PF00443.24 EAU87111.2 - 1.5e-45 155.4 0.0 2.9e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EAU87111.2 - 4.5e-26 90.7 10.2 1.2e-19 70.1 1.2 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EAU87111.2 - 2.2e-25 87.7 0.1 4e-12 45.5 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EAU87111.2 - 5.4e-21 75.3 0.3 4e-20 72.4 0.2 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF695 PF05117.7 EAU87111.2 - 0.11 12.3 0.1 1.4 8.8 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF695) Aldedh PF00171.17 EAU87113.2 - 3.7e-172 572.8 1.1 1.4e-171 570.9 0.8 1.7 1 1 0 1 1 1 1 Aldehyde dehydrogenase family ECH PF00378.15 EAU87114.1 - 6e-35 120.5 0.2 7.2e-33 113.7 0.1 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FSH1 PF03959.8 EAU87114.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HSP70 PF00012.15 EAU87115.1 - 1.6e-58 198.1 0.7 4.8e-46 156.8 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EAU87115.1 - 1.4e-09 36.9 0.0 4e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EAU87115.1 - 0.021 13.7 0.0 0.95 8.2 0.0 2.4 2 1 0 2 2 2 0 Type IV pilus assembly protein PilM; DUF2834 PF11196.3 EAU87116.2 - 8.8e-05 22.5 9.1 0.0036 17.4 0.9 2.8 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) YscJ_FliF PF01514.12 EAU87120.2 - 0.1 11.7 1.5 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family YtxH PF12732.2 EAU87120.2 - 0.23 11.8 3.8 0.45 10.9 2.6 1.4 1 0 0 1 1 1 0 YtxH-like protein BLVR PF06375.6 EAU87123.1 - 0.014 15.2 3.9 0.042 13.6 2.7 1.9 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF755 PF05501.6 EAU87123.1 - 9.4 6.3 23.6 0.25 11.4 6.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Oxysterol_BP PF01237.13 EAU87124.1 - 4.4e-116 387.2 0.0 7.6e-116 386.4 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 EAU87124.1 - 6.5e-15 55.2 0.2 6.6e-11 42.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU87124.1 - 1.1e-14 54.0 3.2 1.8e-08 34.3 0.2 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EAU87124.1 - 1.6e-14 52.9 1.6 0.00027 20.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EAU87124.1 - 2.5e-11 43.7 0.2 7.6e-07 29.4 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU87124.1 - 7e-11 41.2 1.9 0.0009 19.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat PH_8 PF15409.1 EAU87124.1 - 2.9e-09 36.8 1.8 8.6e-09 35.3 0.3 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EAU87124.1 - 8.8e-09 35.5 0.0 2.1e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EAU87124.1 - 8.9e-07 29.1 0.6 2.6e-06 27.6 0.4 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain ubiquitin PF00240.18 EAU87127.1 - 0.00017 20.9 0.3 0.03 13.7 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin family FAD_binding_3 PF01494.14 EAU87128.2 - 7.4e-19 68.0 0.0 1.6e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EAU87128.2 - 0.045 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4520 PF15016.1 EAU87128.2 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) BING4CT PF08149.6 EAU87129.1 - 1.6e-32 110.8 0.0 1.1e-31 108.1 0.0 2.2 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EAU87129.1 - 5.2e-08 32.4 0.3 4.8e-05 23.0 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat CDC45 PF02724.9 EAU87129.1 - 0.26 9.2 10.8 0.49 8.3 7.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Gly-zipper_OmpA PF13436.1 EAU87130.1 - 0.14 11.8 12.1 0.27 10.9 8.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Romo1 PF10247.4 EAU87131.1 - 0.51 10.5 3.1 0.94 9.7 2.2 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Pex14_N PF04695.8 EAU87132.1 - 0.0088 16.1 1.3 0.016 15.2 0.9 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region NAM-associated PF14303.1 EAU87132.1 - 0.17 12.1 6.2 0.23 11.7 4.3 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain vMSA PF00695.14 EAU87132.1 - 0.23 10.6 1.1 0.27 10.4 0.8 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF2076 PF09849.4 EAU87132.1 - 2 8.4 7.6 3.8 7.4 5.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MFS_1 PF07690.11 EAU87133.1 - 3.6e-36 124.6 37.7 3.6e-36 124.6 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU87133.1 - 7.6e-11 41.2 30.2 1.7e-10 40.0 20.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAU87133.1 - 0.00039 18.7 1.7 0.00071 17.8 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mem_trans PF03547.13 EAU87136.1 - 9.4e-31 106.4 0.5 1.2e-30 106.1 0.4 1.1 1 0 0 1 1 1 1 Membrane transport protein Aldedh PF00171.17 EAU87137.1 - 7.4e-186 617.9 1.4 8.4e-186 617.8 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EAU87137.1 - 0.0012 17.6 0.0 0.0039 15.9 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EAU87137.1 - 0.0034 16.6 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) Glyco_hydro_61 PF03443.9 EAU87138.1 - 4.6e-46 157.3 0.0 6.1e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pmp3 PF01679.12 EAU87139.1 - 1.2e-17 63.3 6.1 1.6e-17 62.9 4.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RCR PF12273.3 EAU87139.1 - 1.9 9.0 9.5 2.6 8.6 6.6 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red YL1_C PF08265.6 EAU87140.2 - 1.7e-15 56.2 0.2 3.5e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CPL PF08144.6 EAU87141.1 - 8.2e-23 80.8 0.6 5.4e-21 74.9 0.0 3.8 4 1 2 6 6 6 1 CPL (NUC119) domain PUF PF00806.14 EAU87141.1 - 0.0052 16.1 1.9 1.4 8.5 0.0 3.9 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat B12-binding_2 PF02607.12 EAU87141.1 - 0.07 13.1 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain ubiquitin PF00240.18 EAU87142.1 - 4.7e-09 35.5 0.0 8e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAU87142.1 - 3.7e-07 29.7 0.0 7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like F-box-like PF12937.2 EAU87143.1 - 3e-08 33.2 0.7 8.6e-08 31.7 0.5 1.9 1 0 0 1 1 1 1 F-box-like Microtub_assoc PF07989.6 EAU87143.1 - 0.075 12.8 0.5 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Microtubule associated ESR1_C PF12743.2 EAU87143.1 - 0.22 11.1 2.4 0.23 11.0 0.2 2.1 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal PNP_UDP_1 PF01048.15 EAU87144.2 - 3.1e-27 95.0 0.0 4.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_tran_WecB PF03808.8 EAU87144.2 - 0.026 13.9 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HMG_box PF00505.14 EAU87145.2 - 5e-17 61.9 0.9 8e-17 61.2 0.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU87145.2 - 2.4e-15 56.6 0.5 4.3e-15 55.8 0.3 1.3 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 EAU87145.2 - 0.0027 17.8 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) adh_short_C2 PF13561.1 EAU87146.1 - 3.3e-28 99.0 0.1 4e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU87146.1 - 1.1e-17 64.4 1.6 1.4e-17 64.0 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU87146.1 - 2.2e-09 37.2 0.3 3e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EAU87146.1 - 0.00041 19.4 0.0 0.0016 17.4 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase Flavodoxin_4 PF12682.2 EAU87146.1 - 0.11 11.8 0.1 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin Fasciclin PF02469.17 EAU87149.2 - 1.6e-26 92.7 0.0 3.7e-17 62.5 0.0 2.6 2 0 0 2 2 2 2 Fasciclin domain NAP PF00956.13 EAU87151.2 - 1.4e-79 266.7 4.5 1.4e-79 266.7 3.1 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Bd3614_N PF14442.1 EAU87151.2 - 0.83 9.6 8.8 1.6 8.7 6.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal TauD PF02668.11 EAU87152.1 - 2.2e-53 181.5 0.5 2.7e-53 181.3 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EAU87152.1 - 0.033 14.6 0.9 6.2 7.4 0.0 2.5 1 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily REV PF00424.13 EAU87153.1 - 2.4 8.1 5.5 0.84 9.5 1.9 1.7 2 1 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Toxin_35 PF10530.4 EAU87155.2 - 0.064 13.3 0.4 0.064 13.3 0.3 1.8 2 0 0 2 2 2 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold F-box-like PF12937.2 EAU87156.2 - 0.024 14.3 0.6 0.061 13.0 0.1 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EAU87156.2 - 0.075 12.7 0.2 0.28 10.8 0.2 2.0 1 0 0 1 1 1 0 F-box domain TauD PF02668.11 EAU87157.1 - 4.2e-57 193.7 0.3 5.2e-57 193.4 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EAU87157.1 - 0.0046 17.4 1.3 0.36 11.3 0.0 2.8 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily Fasciclin PF02469.17 EAU87158.1 - 9.2e-24 83.8 0.1 6.6e-14 52.0 0.0 2.6 2 1 0 2 2 2 2 Fasciclin domain SIS_2 PF13580.1 EAU87158.1 - 0.016 14.9 0.1 0.084 12.5 0.1 2.2 1 1 0 1 1 1 0 SIS domain AXE1 PF05448.7 EAU87159.1 - 0.0074 14.8 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF43 PF01861.11 EAU87159.1 - 0.077 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 F-box-like PF12937.2 EAU87160.2 - 6.1e-08 32.2 2.2 1.7e-07 30.8 0.1 2.8 3 0 0 3 3 3 1 F-box-like Pkinase PF00069.20 EAU87161.2 - 1.5e-71 240.5 0.0 1.7e-68 230.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87161.2 - 1e-35 123.0 0.0 5.7e-32 110.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAU87161.2 - 5.7e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EAU87161.2 - 0.0056 16.0 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EAU87161.2 - 0.011 14.7 0.1 0.023 13.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.13 EAU87165.2 - 1.1e-07 31.6 11.3 1.7e-07 31.0 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_1 PF00734.13 EAU87167.1 - 1.4e-13 50.1 13.1 1.4e-13 50.1 9.1 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.7 EAU87167.1 - 0.059 11.8 0.0 0.094 11.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) CBM_1 PF00734.13 EAU87168.1 - 1.2e-11 44.0 12.1 1.2e-11 44.0 8.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Trypan_PARP PF05887.6 EAU87170.2 - 0.0012 18.6 26.7 0.0025 17.6 18.5 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) PhoPQ_related PF10142.4 EAU87170.2 - 0.01 14.3 0.0 0.037 12.5 0.0 1.7 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 EAU87170.2 - 0.12 10.8 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) LysM PF01476.15 EAU87171.1 - 1.9e-13 50.0 0.2 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 LysM domain 3Beta_HSD PF01073.14 EAU87173.2 - 1.7e-12 46.6 0.1 2e-12 46.3 0.1 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAU87173.2 - 5.5e-12 45.6 0.1 6e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU87173.2 - 9.1e-10 38.8 1.1 1.1e-09 38.6 0.7 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EAU87173.2 - 1.7e-06 27.5 0.4 1.9e-06 27.3 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EAU87173.2 - 1.9e-06 26.9 0.2 0.024 13.5 0.0 2.0 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EAU87173.2 - 0.00035 19.5 0.2 0.0024 16.8 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EAU87173.2 - 0.019 14.8 1.6 0.077 12.9 1.1 1.8 1 1 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 EAU87174.2 - 2.5e-22 79.0 17.9 3.7e-22 78.5 12.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU87174.2 - 0.0016 17.1 3.5 0.0025 16.4 2.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Aminotran_5 PF00266.14 EAU87175.1 - 1.7e-20 73.1 0.0 2.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EAU87175.1 - 2.8e-06 26.6 0.3 2.2e-05 23.6 0.2 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EAU87175.1 - 1.6e-05 24.0 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EAU87175.1 - 0.0067 14.9 0.1 0.013 13.9 0.1 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain polyprenyl_synt PF00348.12 EAU87176.2 - 2.4e-44 151.1 0.0 4e-41 140.5 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Chitin_synth_1 PF01644.12 EAU87177.1 - 1.2e-63 213.7 0.2 2e-63 213.0 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EAU87177.1 - 3.8e-27 93.7 0.1 8e-27 92.7 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EAU87177.1 - 6.7e-25 87.4 0.1 5.4e-21 74.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EAU87177.1 - 2e-13 50.4 2.4 2e-13 50.4 1.7 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAU87177.1 - 4.1e-08 33.3 0.0 1.2e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 zf-4CXXC_R1 PF10497.4 EAU87178.2 - 9.4e-06 25.7 16.7 2e-05 24.6 11.6 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 HSP20 PF00011.16 EAU87179.1 - 6.8e-22 77.2 0.0 9.7e-22 76.7 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EAU87179.1 - 0.00072 19.1 0.1 0.00097 18.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) BON PF04972.12 EAU87179.1 - 0.015 14.9 0.3 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 BON domain CS PF04969.11 EAU87179.1 - 0.05 14.1 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 CS domain Acetyltransf_1 PF00583.19 EAU87181.1 - 1.2e-10 41.2 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU87181.1 - 6.5e-10 39.0 0.0 9.4e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAU87181.1 - 0.016 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAU87181.1 - 0.023 14.8 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 EAU87183.2 - 4.2e-09 36.0 0.0 6.8e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU87183.2 - 3e-08 33.3 0.2 1.2e-07 31.4 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Acyl_transf_1 PF00698.16 EAU87184.2 - 4.8e-47 160.8 0.0 6.8e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EAU87184.2 - 5.9e-38 130.7 0.0 1.8e-37 129.0 0.0 1.8 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EAU87184.2 - 3.7e-34 117.9 0.2 7.4e-31 107.2 0.0 2.6 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 EAU87184.2 - 1.1e-31 109.9 0.4 2.3e-27 95.9 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EAU87184.2 - 6.6e-24 84.1 0.1 5.9e-11 41.7 0.0 2.8 3 0 0 3 3 3 2 Male sterility protein Ketoacyl-synt_C PF02801.17 EAU87184.2 - 2e-21 76.0 0.0 3.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 EAU87184.2 - 2.1e-08 33.8 0.0 0.076 12.4 0.0 3.6 2 1 1 3 3 3 3 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EAU87184.2 - 2.7e-06 27.5 0.1 7e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EAU87184.2 - 0.11 11.3 0.0 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EAU87184.2 - 0.18 11.7 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Tyrosinase PF00264.15 EAU87191.2 - 2.2e-37 129.4 0.1 3.6e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Peroxidase_2 PF01328.12 EAU87192.2 - 2.5e-20 72.4 3.1 1.6e-19 69.7 2.1 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 RabGAP-TBC PF00566.13 EAU87193.2 - 4.9e-27 94.8 0.0 8.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.12 EAU87193.2 - 0.0024 17.3 0.0 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF104 PF01954.11 EAU87194.2 - 0.36 10.9 5.8 6.2 6.9 0.5 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF104 Peroxidase_2 PF01328.12 EAU87196.2 - 1.8e-16 59.7 0.9 8.3e-09 34.5 0.1 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 DUF1996 PF09362.5 EAU87197.2 - 2.1e-66 223.9 0.0 6.2e-66 222.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1586 PF07625.6 EAU87198.1 - 0.0011 18.6 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1586) AATF-Che1 PF13339.1 EAU87198.1 - 0.027 14.6 1.7 0.044 13.9 1.2 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Peptidase_M50 PF02163.17 EAU87200.1 - 0.033 13.1 0.1 0.15 11.0 0.1 2.3 1 1 0 1 1 1 0 Peptidase family M50 Acyl_transf_3 PF01757.17 EAU87200.1 - 0.037 12.8 19.4 0.0078 15.0 7.6 2.7 2 1 1 3 3 3 0 Acyltransferase family BphX PF06139.7 EAU87200.1 - 0.13 11.8 3.2 6.9 6.2 0.1 2.9 2 1 0 2 2 2 0 BphX-like DUF3671 PF12420.3 EAU87200.1 - 0.66 9.9 0.0 0.66 9.9 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function Fig1 PF12351.3 EAU87200.1 - 1 9.2 6.8 0.95 9.3 0.3 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 zf-DHHC PF01529.15 EAU87200.1 - 9.8 5.5 9.1 2.7e+02 0.8 6.3 2.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Nucleoplasmin PF03066.10 EAU87209.2 - 0.16 11.4 6.3 0.28 10.6 4.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EAU87209.2 - 0.6 9.6 4.9 0.72 9.4 3.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 EAU87209.2 - 0.97 8.6 9.7 1.3 8.1 6.7 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EAU87209.2 - 5.7 5.5 14.9 6.3 5.3 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Homeobox PF00046.24 EAU87213.2 - 0.00068 19.2 1.5 0.0024 17.4 0.2 2.1 2 0 0 2 2 2 1 Homeobox domain DUF4149 PF13664.1 EAU87215.2 - 0.94 9.5 5.5 3.5 7.7 0.1 3.0 2 1 0 3 3 3 0 Domain of unknown function (DUF4149) Trep_Strep PF09605.5 EAU87216.2 - 0.15 11.7 6.2 0.35 10.5 0.9 2.6 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2231 PF09990.4 EAU87216.2 - 0.32 11.3 10.1 0.24 11.7 0.4 3.1 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) G_glu_transpept PF01019.16 EAU87217.2 - 0.0011 17.4 0.2 0.0016 17.0 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF4079 PF13301.1 EAU87218.1 - 0.36 10.8 2.8 0.24 11.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Ras PF00071.17 EAU87220.2 - 1.1e-19 70.3 0.0 1.9e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU87220.2 - 3e-07 30.9 0.0 5.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU87220.2 - 0.016 14.4 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family PolyA_pol_arg_C PF12626.2 EAU87220.2 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus ABC2_membrane PF01061.19 EAU87223.1 - 3.8e-29 101.3 21.3 6.2e-29 100.6 14.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EAU87223.1 - 1.9e-26 92.9 0.0 2.9e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU87223.1 - 2.2e-07 31.1 0.0 0.00055 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAU87223.1 - 3.4e-05 23.9 0.1 7e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EAU87223.1 - 6.8e-05 22.2 0.0 0.082 12.1 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAU87223.1 - 8e-05 22.0 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EAU87223.1 - 0.00029 20.0 0.1 0.00048 19.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAU87223.1 - 0.00046 20.3 0.0 0.0031 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAU87223.1 - 0.0066 15.8 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EAU87223.1 - 0.0077 16.5 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EAU87223.1 - 0.027 14.3 1.3 0.055 13.3 0.0 2.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EAU87223.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EAU87223.1 - 0.17 12.7 0.0 0.31 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain V-SNARE PF05008.10 EAU87224.1 - 1.8e-21 76.0 2.1 2.9e-21 75.4 0.2 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EAU87224.1 - 1.1e-13 50.9 2.0 3.4e-13 49.4 1.4 1.9 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EAU87224.1 - 0.038 13.6 0.1 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Sec20 Prominin PF05478.6 EAU87224.1 - 0.15 9.5 0.1 0.25 8.8 0.0 1.4 2 0 0 2 2 2 0 Prominin DUF4127 PF13552.1 EAU87228.2 - 0.033 12.5 0.1 0.051 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) FlbD PF06289.6 EAU87228.2 - 0.099 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Flagellar protein (FlbD) Nop14 PF04147.7 EAU87228.2 - 0.11 10.4 4.6 0.15 9.9 3.2 1.3 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_67M PF07488.7 EAU87230.2 - 0.15 10.9 1.2 0.16 10.8 0.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 middle domain DUF2296 PF10058.4 EAU87230.2 - 4.5 7.0 5.1 48 3.8 0.1 3.4 3 1 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) DUF3733 PF12534.3 EAU87230.2 - 7.8 5.8 7.6 17 4.7 0.1 3.0 1 1 2 3 3 3 0 Leucine-rich repeat containing protein 8 F-box-like PF12937.2 EAU87234.2 - 0.00031 20.4 0.2 0.00072 19.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU87235.1 - 0.0028 17.3 0.2 0.0062 16.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF1240 PF06836.7 EAU87236.2 - 0.043 14.0 2.5 0.048 13.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) 4HBT_2 PF13279.1 EAU87237.2 - 4.5e-08 33.5 0.0 7.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF3808 PF10300.4 EAU87238.1 - 1.7e-81 274.1 0.0 2.7e-81 273.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EAU87238.1 - 1.3e-06 27.9 0.4 0.0043 16.6 0.1 3.3 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EAU87238.1 - 0.00057 19.7 5.1 0.15 12.0 0.1 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU87238.1 - 0.0022 18.6 1.0 0.09 13.4 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU87238.1 - 0.0023 17.7 10.8 0.012 15.4 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EAU87238.1 - 0.054 13.9 1.1 0.25 11.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU87238.1 - 5.3 6.8 8.1 17 5.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_11 PF00457.12 EAU87239.1 - 4.2e-77 257.6 20.2 4.9e-77 257.4 14.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF3740 PF12548.3 EAU87239.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Sulfatase protein CCDC14 PF15254.1 EAU87241.1 - 0.059 11.7 0.9 0.07 11.5 0.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 SUZ PF12752.2 EAU87243.2 - 0.063 13.8 0.5 0.063 13.8 0.3 2.6 2 0 0 2 2 2 0 SUZ domain Aldo_ket_red PF00248.16 EAU87247.2 - 5.9e-36 123.7 0.0 7.6e-36 123.3 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2025 PF09634.5 EAU87247.2 - 0.087 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) DUF3089 PF11288.3 EAU87248.2 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) DUF3901 PF13040.1 EAU87249.2 - 0.067 12.4 0.5 0.1 11.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) Peptidase_M43 PF05572.8 EAU87254.2 - 4.9e-19 68.4 0.0 8.2e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU87254.2 - 4.9e-06 26.5 0.1 4.7e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAU87254.2 - 7.9e-05 22.7 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAU87254.2 - 0.00012 22.6 0.1 0.00052 20.5 0.0 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU87254.2 - 0.0012 18.3 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87254.2 - 0.006 16.3 0.0 0.0089 15.7 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EAU87254.2 - 0.055 12.3 0.4 0.14 10.9 0.4 1.5 2 0 0 2 2 2 0 Peptidase M66 Peptidase_M43 PF05572.8 EAU87255.2 - 3.7e-16 59.0 0.2 1.4e-15 57.2 0.1 1.8 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU87255.2 - 2.2e-06 27.7 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU87255.2 - 4.6e-05 23.9 0.0 8.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU87255.2 - 0.00012 22.2 0.1 0.00021 21.4 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EAU87255.2 - 0.0043 16.4 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 EAU87255.2 - 0.014 14.9 0.2 0.033 13.7 0.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87255.2 - 0.098 12.3 0.2 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M43 PF05572.8 EAU87257.2 - 1.9e-14 53.5 0.1 3.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EAU87257.2 - 0.00013 22.4 0.1 0.00024 21.6 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU87257.2 - 0.00017 21.5 0.0 0.00036 20.5 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAU87257.2 - 0.012 15.6 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87257.2 - 0.069 12.8 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.3 EAU87257.2 - 0.12 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1025 PF06262.6 EAU87257.2 - 0.21 11.3 1.1 7 6.5 0.4 2.7 3 0 0 3 3 3 0 Possibl zinc metallo-peptidase Peptidase_M3_N PF08439.5 EAU87260.2 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Oligopeptidase F BTB PF00651.26 EAU87260.2 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain zf-MYND PF01753.13 EAU87264.1 - 1.1e-07 31.5 8.9 2.4e-07 30.5 6.2 1.6 1 0 0 1 1 1 1 MYND finger TLD PF07534.11 EAU87265.2 - 1e-26 93.6 0.1 8.5e-26 90.6 0.0 2.2 1 1 0 1 1 1 1 TLD Oxidored_FMN PF00724.15 EAU87267.1 - 3e-95 319.1 0.0 3.4e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EAU87267.1 - 0.098 11.9 0.1 0.31 10.3 0.0 1.7 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel OPT PF03169.10 EAU87268.2 - 1.1e-153 512.9 41.8 1.3e-153 512.7 29.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Tyrosinase PF00264.15 EAU87270.2 - 2.3e-31 109.7 0.0 3.9e-31 108.9 0.0 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase F-box-like PF12937.2 EAU87273.1 - 1.3e-05 24.8 1.1 1.3e-05 24.8 0.8 3.4 4 0 0 4 4 4 1 F-box-like HMG_box PF00505.14 EAU87276.1 - 8.3e-12 45.1 5.2 5.2e-11 42.6 3.6 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU87276.1 - 0.0076 16.5 3.6 0.02 15.2 2.5 1.8 1 0 0 1 1 1 1 HMG-box domain PSII_BNR PF14870.1 EAU87277.2 - 0.046 12.7 0.2 0.11 11.5 0.1 1.6 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Metallophos PF00149.23 EAU87279.2 - 3.3e-35 121.2 0.1 4.3e-35 120.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PSII_BNR PF14870.1 EAU87280.1 - 0.015 14.2 0.1 0.026 13.5 0.0 1.4 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Med15 PF09606.5 EAU87281.2 - 0.77 7.8 51.6 0.92 7.6 35.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GPP34 PF05719.6 EAU87282.2 - 1.1e-60 205.2 0.0 1.3e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) KRTAP7 PF15034.1 EAU87282.2 - 0.038 14.6 0.7 0.071 13.7 0.5 1.4 1 0 0 1 1 1 0 KRTAP type 7 family Tim54 PF11711.3 EAU87283.2 - 0.014 14.0 5.7 0.013 14.0 4.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CENP-T PF15511.1 EAU87283.2 - 0.056 12.6 14.3 0.065 12.4 9.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 EAU87283.2 - 0.15 11.4 19.7 0.17 11.3 13.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CKAP2_C PF15297.1 EAU87283.2 - 0.21 10.3 12.8 0.24 10.1 8.9 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus AUX_IAA PF02309.11 EAU87283.2 - 0.26 11.0 13.7 0.29 10.8 9.5 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4045 PF13254.1 EAU87283.2 - 0.28 10.4 11.1 0.31 10.2 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 EAU87283.2 - 0.29 8.7 14.1 0.29 8.7 9.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dala_Dala_lig_N PF01820.16 EAU87283.2 - 0.41 10.9 5.4 0.51 10.6 3.7 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Gti1_Pac2 PF09729.4 EAU87283.2 - 0.47 10.3 8.9 0.52 10.1 6.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Ctr PF04145.10 EAU87283.2 - 0.59 10.1 7.1 0.71 9.9 4.9 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF1764 PF08576.5 EAU87283.2 - 0.62 10.8 17.5 0.9 10.3 12.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SAPS PF04499.10 EAU87283.2 - 0.65 8.5 9.6 0.64 8.5 6.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Band_3_cyto PF07565.8 EAU87283.2 - 0.67 9.4 14.2 0.73 9.2 9.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.1 EAU87283.2 - 0.68 7.5 47.2 0.71 7.4 32.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SAGA-Tad1 PF12767.2 EAU87283.2 - 0.68 9.5 17.9 0.79 9.3 12.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4557 PF15101.1 EAU87283.2 - 0.73 9.6 27.9 0.82 9.4 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ycf1 PF05758.7 EAU87283.2 - 0.73 7.4 13.0 0.74 7.4 9.0 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 EAU87283.2 - 0.74 9.5 12.9 0.87 9.3 8.9 1.1 1 0 0 1 1 1 0 DDHD domain FAM176 PF14851.1 EAU87283.2 - 0.74 9.4 7.4 0.89 9.2 5.1 1.1 1 0 0 1 1 1 0 FAM176 family FAM60A PF15396.1 EAU87283.2 - 0.76 9.4 8.9 0.83 9.3 6.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3395 PF11875.3 EAU87283.2 - 0.77 9.3 13.7 0.84 9.2 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Raftlin PF15250.1 EAU87283.2 - 0.78 8.1 12.8 0.83 8.1 8.9 1.0 1 0 0 1 1 1 0 Raftlin F-protein PF00469.15 EAU87283.2 - 0.78 9.0 12.6 0.92 8.8 8.7 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Pal1 PF08316.6 EAU87283.2 - 0.79 10.1 6.8 0.9 9.9 4.7 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Plasmodium_Vir PF05795.6 EAU87283.2 - 0.8 8.8 4.6 0.81 8.8 3.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Rtf2 PF04641.7 EAU87283.2 - 0.83 8.8 12.2 0.94 8.6 8.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Neur_chan_memb PF02932.11 EAU87283.2 - 0.86 9.4 9.8 0.89 9.3 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.3 EAU87283.2 - 0.9 7.6 9.0 0.87 7.7 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TFIIA PF03153.8 EAU87283.2 - 0.92 9.3 30.4 1 9.1 21.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_PP31 PF05311.6 EAU87283.2 - 0.93 8.7 14.2 1.1 8.4 9.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDC45 PF02724.9 EAU87283.2 - 0.95 7.4 12.9 1.1 7.2 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein HGTP_anticodon2 PF12745.2 EAU87283.2 - 0.98 8.5 12.5 1.1 8.2 8.6 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs FLO_LFY PF01698.11 EAU87283.2 - 1.1 7.9 15.3 1.4 7.7 10.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein EPL1 PF10513.4 EAU87283.2 - 1.3 9.2 16.4 1.5 9.0 11.4 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Hom_end_hint PF05203.11 EAU87283.2 - 1.3 8.7 8.3 1.5 8.5 5.7 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Pex16 PF08610.5 EAU87283.2 - 1.4 7.8 13.9 1.4 7.8 9.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FHIPEP PF00771.15 EAU87283.2 - 1.4 7.1 7.8 1.5 7.0 5.4 1.1 1 0 0 1 1 1 0 FHIPEP family Bud13 PF09736.4 EAU87283.2 - 1.4 9.1 22.0 1.7 8.8 15.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DHHW PF14286.1 EAU87283.2 - 1.5 8.0 11.1 1.6 7.9 7.7 1.1 1 0 0 1 1 1 0 DHHW protein RR_TM4-6 PF06459.7 EAU87283.2 - 1.5 8.6 14.2 1.6 8.5 9.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GOLD_2 PF13897.1 EAU87283.2 - 1.6 8.9 5.3 1.9 8.6 3.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PIH1 PF08190.7 EAU87283.2 - 1.7 7.9 20.5 1.9 7.8 14.2 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RED_N PF07808.8 EAU87283.2 - 1.9 7.6 22.3 2.2 7.4 15.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Gag_spuma PF03276.9 EAU87283.2 - 1.9 6.6 35.5 2.1 6.5 24.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF2072 PF09845.4 EAU87283.2 - 2 8.3 6.8 2.5 8.0 4.7 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) AIF_C PF14721.1 EAU87283.2 - 2.1 8.6 13.4 2.8 8.1 9.3 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Senescence_reg PF04520.8 EAU87283.2 - 2.1 8.8 12.6 2.5 8.5 8.7 1.1 1 0 0 1 1 1 0 Senescence regulator Herpes_DNAp_acc PF04929.7 EAU87283.2 - 2.5 6.9 10.5 2.5 6.9 7.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor VIT1 PF01988.14 EAU87283.2 - 2.5 7.5 3.8 3 7.2 2.6 1.2 1 0 0 1 1 1 0 VIT family DDRGK PF09756.4 EAU87283.2 - 2.9 7.2 23.0 3.5 6.9 15.9 1.1 1 0 0 1 1 1 0 DDRGK domain PAT1 PF09770.4 EAU87283.2 - 2.9 5.9 48.7 3.1 5.9 33.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cyto_heme_lyase PF01265.12 EAU87283.2 - 3.2 7.2 15.9 3.8 7.0 11.0 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase PBP1_TM PF14812.1 EAU87283.2 - 3.2 8.1 7.9 4.4 7.6 5.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CPSF100_C PF13299.1 EAU87283.2 - 3.2 7.9 14.0 3.9 7.6 9.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3373 PF11853.3 EAU87283.2 - 3.3 6.1 11.0 3.3 6.1 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4512 PF14975.1 EAU87283.2 - 3.5 8.5 7.6 4.6 8.1 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Mem_trans PF03547.13 EAU87283.2 - 3.6 5.7 5.8 3.7 5.7 4.0 1.0 1 0 0 1 1 1 0 Membrane transport protein Paramyxo_ncap PF00973.14 EAU87283.2 - 4.1 5.9 10.4 4.4 5.8 7.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Herpes_env PF01673.13 EAU87283.2 - 4.2 5.8 9.4 4.3 5.7 6.5 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein NARP1 PF12569.3 EAU87283.2 - 4.2 6.0 16.7 5 5.7 11.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YABBY PF04690.8 EAU87283.2 - 4.3 7.5 13.4 5.2 7.2 9.3 1.1 1 0 0 1 1 1 0 YABBY protein G-7-MTase PF12803.2 EAU87283.2 - 4.3 6.3 7.3 4.6 6.2 5.1 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Glyco_transf_15 PF01793.11 EAU87283.2 - 4.4 6.1 15.0 5.3 5.8 10.4 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF3306 PF11748.3 EAU87283.2 - 4.5 7.9 15.3 6.1 7.5 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) CobT PF06213.7 EAU87283.2 - 4.8 6.2 14.0 5.9 5.9 9.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4638 PF15472.1 EAU87283.2 - 5.1 6.6 12.0 5.8 6.4 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Bul1_N PF04425.7 EAU87283.2 - 5.9 5.3 12.3 6.2 5.2 8.5 1.1 1 0 0 1 1 1 0 Bul1 N terminus Peptidase_S49_N PF08496.5 EAU87283.2 - 6.4 6.5 14.1 8.8 6.1 9.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NPR3 PF03666.8 EAU87283.2 - 6.5 5.1 14.2 6.9 5.0 9.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 YfhO PF09586.5 EAU87283.2 - 7.5 4.4 10.6 8.1 4.3 7.3 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO R_equi_Vir PF05526.6 EAU87283.2 - 7.8 6.0 7.9 8.6 5.9 5.5 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Peroxin-13_N PF04088.8 EAU87283.2 - 8.1 6.3 8.8 12 5.8 6.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Maf1 PF09174.5 EAU87283.2 - 8.1 6.2 8.5 9.6 6.0 5.9 1.2 1 0 0 1 1 1 0 Maf1 regulator Dicty_REP PF05086.7 EAU87283.2 - 8.2 4.0 9.6 7.6 4.1 6.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Spc7_N PF15402.1 EAU87283.2 - 8.2 4.2 18.7 9 4.1 13.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 OmpH PF03938.9 EAU87283.2 - 8.3 6.3 37.2 9.7 6.1 25.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EAU87283.2 - 8.7 5.2 19.3 10 5.0 13.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3408 PF11888.3 EAU87283.2 - 8.8 6.2 14.9 12 5.8 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CDK5_activator PF03261.10 EAU87283.2 - 9.1 5.5 14.4 9.7 5.4 10.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Presenilin PF01080.12 EAU87283.2 - 9.2 4.9 8.7 9.6 4.9 6.0 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.7 EAU87283.2 - 9.4 4.7 23.6 10 4.5 16.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoVR PF04293.8 EAU87283.2 - 9.4 4.4 15.3 11 4.2 10.6 1.0 1 0 0 1 1 1 0 SpoVR like protein FAM91_C PF14648.1 EAU87283.2 - 9.4 4.9 8.3 11 4.7 5.8 1.1 1 0 0 1 1 1 0 FAM91 C-terminus BNR_3 PF13859.1 EAU87283.2 - 9.5 5.1 7.8 11 4.9 5.4 1.1 1 0 0 1 1 1 0 BNR repeat-like domain Serinc PF03348.10 EAU87283.2 - 9.8 4.7 16.2 11 4.5 11.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) ARF7EP_C PF14949.1 EAU87283.2 - 10 6.6 15.3 14 6.1 10.6 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus p450 PF00067.17 EAU87285.2 - 3.7e-64 216.9 0.0 4.8e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HrcA PF01628.16 EAU87294.2 - 0.048 13.2 0.1 0.062 12.8 0.1 1.1 1 0 0 1 1 1 0 HrcA protein C terminal domain DNA_topoisoIV PF00521.15 EAU87295.2 - 4.9e-48 164.0 5.3 1.7e-27 96.3 0.2 3.2 2 1 1 3 3 3 2 DNA gyrase/topoisomerase IV, subunit A Toprim PF01751.17 EAU87295.2 - 6.2e-15 54.9 0.0 1.6e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EAU87295.2 - 1.5e-08 34.3 0.0 3.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EAU87295.2 - 3.3e-05 23.5 0.6 9.6e-05 22.0 0.4 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PspA_IM30 PF04012.7 EAU87295.2 - 0.00018 20.9 1.1 0.00036 19.9 0.8 1.4 1 0 0 1 1 1 1 PspA/IM30 family TSC22 PF01166.13 EAU87295.2 - 0.002 18.0 1.4 0.0064 16.4 0.9 1.9 1 0 0 1 1 1 1 TSC-22/dip/bun family DNA_gyraseB PF00204.20 EAU87295.2 - 0.0024 17.1 0.1 0.0067 15.6 0.0 1.7 1 0 0 1 1 1 1 DNA gyrase B Cauli_AT PF03233.8 EAU87295.2 - 0.0047 16.6 0.0 0.016 14.8 0.0 1.9 1 0 0 1 1 1 1 Aphid transmission protein HrpB7 PF09486.5 EAU87295.2 - 0.009 15.9 0.6 0.017 15.0 0.4 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Jnk-SapK_ap_N PF09744.4 EAU87295.2 - 0.012 15.6 1.2 0.012 15.6 0.9 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Uds1 PF15456.1 EAU87295.2 - 0.012 15.5 3.3 0.014 15.3 1.3 1.9 2 0 0 2 2 1 0 Up-regulated During Septation IncA PF04156.9 EAU87295.2 - 0.05 13.2 1.4 0.097 12.2 1.0 1.4 1 0 0 1 1 1 0 IncA protein DUF641 PF04859.7 EAU87295.2 - 0.061 13.0 1.2 0.14 11.9 0.8 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 EAU87295.2 - 0.07 13.4 1.1 0.32 11.3 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Viral_P18 PF04521.8 EAU87295.2 - 0.12 11.8 0.6 0.26 10.7 0.4 1.5 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF3186 PF11382.3 EAU87295.2 - 0.45 9.6 3.4 1.6 7.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) Tet_JBP PF12851.2 EAU87306.1 - 8e-13 48.0 0.0 1.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF2130 PF09903.4 EAU87306.1 - 0.18 10.5 1.8 0.27 9.9 1.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) zf-B_box PF00643.19 EAU87312.2 - 8.5 6.3 11.4 0.67 9.8 3.3 2.6 3 0 0 3 3 3 0 B-box zinc finger COG2 PF06148.6 EAU87314.1 - 0.00022 21.1 3.6 0.0004 20.2 0.6 2.6 1 1 2 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Rootletin PF15035.1 EAU87314.1 - 0.00044 20.2 7.4 0.0013 18.7 1.7 2.5 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 EAU87314.1 - 0.00048 19.9 0.7 0.53 10.1 0.1 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus EzrA PF06160.7 EAU87314.1 - 0.0015 16.8 6.1 0.0034 15.6 3.9 1.8 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA IncA PF04156.9 EAU87314.1 - 0.002 17.7 3.0 0.002 17.7 2.1 2.7 2 1 1 3 3 2 1 IncA protein CENP-F_leu_zip PF10473.4 EAU87314.1 - 0.0022 17.8 3.1 0.0022 17.8 2.2 3.4 2 1 0 3 3 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.20 EAU87314.1 - 0.0025 17.9 3.9 0.0025 17.9 2.7 2.3 2 0 0 2 2 1 1 Syntaxin Reo_sigmaC PF04582.7 EAU87314.1 - 0.0028 16.8 0.1 0.0047 16.1 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Filament PF00038.16 EAU87314.1 - 0.0029 17.1 5.3 0.0029 17.1 3.7 2.8 3 1 1 4 4 2 1 Intermediate filament protein Laminin_II PF06009.7 EAU87314.1 - 0.0038 17.0 4.7 0.0078 15.9 2.3 2.2 1 1 1 2 2 2 1 Laminin Domain II Atg14 PF10186.4 EAU87314.1 - 0.0097 14.8 3.8 0.024 13.6 2.6 1.6 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EAU87314.1 - 0.011 14.4 4.1 0.022 13.4 2.8 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.6 EAU87314.1 - 0.035 13.4 3.8 0.082 12.2 1.6 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF445 PF04286.7 EAU87314.1 - 0.039 13.4 5.5 0.072 12.6 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Syntaxin-6_N PF09177.6 EAU87314.1 - 0.097 13.0 4.4 0.3 11.5 0.8 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMPIT PF07851.8 EAU87314.1 - 0.17 10.9 2.1 0.31 10.0 1.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.7 EAU87314.1 - 0.26 11.5 9.0 0.85 9.9 2.1 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 EAU87314.1 - 0.27 9.0 5.1 0.48 8.2 3.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.6 EAU87314.1 - 0.33 8.4 3.7 3.8 4.9 0.3 1.9 1 1 1 2 2 2 0 Prominin MAD PF05557.8 EAU87314.1 - 0.4 8.7 16.6 0.023 12.8 7.1 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF2968 PF11180.3 EAU87314.1 - 0.44 9.9 6.5 0.11 11.8 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Fib_alpha PF08702.5 EAU87314.1 - 0.59 10.2 6.7 1.3 9.1 4.1 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EAU87314.1 - 0.88 9.4 4.6 2.2 8.2 1.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 EAU87314.1 - 1.3 8.5 16.8 0.012 15.1 4.1 2.7 2 1 1 3 3 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EAU87314.1 - 2.6 7.8 5.6 5.2 6.8 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.16 EAU87314.1 - 4.5 6.9 6.5 29 4.3 2.0 2.7 1 1 1 2 2 2 0 Synaptobrevin AATF-Che1 PF13339.1 EAU87314.1 - 9.3 6.4 12.8 0.15 12.2 0.4 3.2 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor SCHIP-1 PF10148.4 EAU87318.2 - 5.6 6.2 8.8 24 4.2 0.0 2.1 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 MTBP_C PF14920.1 EAU87320.2 - 0.0067 15.9 1.7 0.0067 15.9 1.2 2.4 3 0 0 3 3 3 1 MDM2-binding YicC_N PF03755.8 EAU87320.2 - 0.062 13.2 1.0 0.11 12.4 0.7 1.3 1 0 0 1 1 1 0 YicC-like family, N-terminal region ACR_tran PF00873.14 EAU87320.2 - 0.1 9.9 0.0 0.13 9.6 0.0 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Ribosomal_L31 PF01197.13 EAU87324.1 - 0.072 13.0 0.1 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 Ribosomal protein L31 zf-MYND PF01753.13 EAU87325.2 - 1e-09 38.1 12.8 2e-09 37.1 8.9 1.5 1 0 0 1 1 1 1 MYND finger TPR_16 PF13432.1 EAU87325.2 - 8.4e-07 29.5 0.7 0.0086 16.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU87325.2 - 7.4e-06 25.5 0.1 1 9.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU87325.2 - 1.6e-05 24.4 0.0 0.051 13.2 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EAU87325.2 - 5.9e-05 22.9 1.3 0.77 9.7 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAU87325.2 - 6.9e-05 22.6 1.2 11 6.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAU87325.2 - 0.002 17.7 0.0 0.59 10.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU87325.2 - 0.0042 17.5 4.4 1.2 9.9 0.1 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU87325.2 - 0.02 14.5 0.1 3.4 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAU87325.2 - 0.11 12.3 0.3 29 4.6 0.0 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Ribosomal_S19 PF00203.16 EAU87326.1 - 2.3e-23 81.5 0.1 2.8e-23 81.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3592 PF12158.3 EAU87327.2 - 0.069 12.9 0.5 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Pkinase PF00069.20 EAU87328.1 - 1.3e-74 250.6 0.3 2.9e-74 249.5 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87328.1 - 4.5e-52 176.6 0.3 4.5e-52 176.6 0.2 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EAU87328.1 - 1.3e-20 73.5 0.0 3.8e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EAU87328.1 - 8.2e-08 31.5 0.0 1.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EAU87328.1 - 1.7e-05 24.9 0.3 3.8e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.18 EAU87328.1 - 0.00019 21.2 5.5 0.0013 18.5 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF1777 PF08648.7 EAU87328.1 - 0.01 15.5 24.3 0.018 14.7 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Seadorna_VP7 PF07387.6 EAU87328.1 - 0.028 13.2 0.1 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 IBR PF01485.16 EAU87331.2 - 3.1e-14 52.5 29.6 2.8e-07 30.2 1.3 3.7 3 0 0 3 3 3 2 IBR domain UPF0547 PF10571.4 EAU87331.2 - 3.4 7.4 14.0 0.25 11.0 4.1 3.2 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 ApoO PF09769.4 EAU87335.1 - 6.6e-32 110.4 0.1 1.5e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Apolipoprotein O OTT_1508_deam PF14441.1 EAU87337.2 - 3.6e-34 117.6 0.0 5.9e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Pkinase PF00069.20 EAU87338.1 - 0.0064 15.6 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87338.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase PaaX_C PF08223.6 EAU87339.2 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Metallophos PF00149.23 EAU87343.2 - 1.5e-32 112.6 0.0 1.2e-31 109.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase peroxidase PF00141.18 EAU87345.1 - 1.3e-24 86.9 0.0 2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EAU87345.1 - 5e-24 83.9 0.3 1.1e-23 82.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) DUF4588 PF15251.1 EAU87346.1 - 0.1 12.5 15.3 1.4 8.8 10.6 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) Glyco_tranf_2_5 PF13712.1 EAU87346.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family F-box-like PF12937.2 EAU87351.2 - 4.7e-06 26.2 0.1 8.9e-05 22.1 0.0 2.9 2 1 0 2 2 2 1 F-box-like DUF2322 PF10084.4 EAU87351.2 - 0.038 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) F-box-like PF12937.2 EAU87352.2 - 6.8e-06 25.7 4.2 4e-05 23.2 0.5 3.5 3 1 0 3 3 3 1 F-box-like F-box-like PF12937.2 EAU87353.2 - 3.9e-06 26.4 0.4 0.00018 21.1 0.1 3.1 2 1 0 2 2 2 1 F-box-like SnoaL_2 PF12680.2 EAU87354.2 - 0.0014 19.0 0.0 0.0017 18.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF3367 PF11847.3 EAU87354.2 - 0.11 10.4 0.1 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) APCDDC PF14921.1 EAU87354.2 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 1 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 DUF563 PF04577.9 EAU87355.2 - 1.6e-17 64.1 0.0 5.9e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) F-box-like PF12937.2 EAU87357.2 - 0.00043 19.9 3.6 0.00043 19.9 2.5 2.9 3 1 0 3 3 3 1 F-box-like zf-MYND PF01753.13 EAU87358.1 - 2.8e-06 27.1 8.8 5.9e-06 26.0 6.1 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU87358.1 - 0.031 14.1 2.3 0.091 12.6 1.6 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ADH_zinc_N PF00107.21 EAU87359.1 - 6.6e-17 61.2 0.0 1.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU87359.1 - 5e-12 45.5 0.0 8.5e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 EAU87360.2 - 2.4e-09 36.7 4.6 0.0023 17.6 0.3 4.0 3 0 0 3 3 3 2 F-box-like Fibrillarin_2 PF10113.4 EAU87360.2 - 0.063 11.6 0.0 0.089 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Ras PF00071.17 EAU87363.2 - 9e-40 135.7 0.3 2e-38 131.2 0.2 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EAU87363.2 - 1e-13 51.8 0.0 2.3e-13 50.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAU87363.2 - 1.5e-05 24.2 0.0 0.00097 18.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU87363.2 - 7.5e-05 22.2 0.0 0.00024 20.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAU87363.2 - 0.00027 20.8 0.0 0.00064 19.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EAU87363.2 - 0.00034 20.7 0.0 0.00057 20.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAU87363.2 - 0.00043 19.4 0.0 0.00088 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAU87363.2 - 0.0018 18.2 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EAU87363.2 - 0.0049 16.6 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase Septin PF00735.13 EAU87363.2 - 0.0059 15.6 0.3 0.0095 14.9 0.0 1.5 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 EAU87363.2 - 0.006 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EAU87363.2 - 0.0062 16.0 0.5 0.016 14.7 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EAU87363.2 - 0.0077 15.9 0.2 0.12 12.0 0.0 2.3 2 1 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 EAU87363.2 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain MobB PF03205.9 EAU87363.2 - 0.012 15.3 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EAU87363.2 - 0.056 12.6 0.1 0.087 12.0 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.14 EAU87363.2 - 0.062 12.7 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EAU87363.2 - 0.062 13.5 0.1 0.083 13.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EAU87363.2 - 0.094 12.6 0.1 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAU87363.2 - 0.099 12.8 0.0 0.35 11.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EAU87363.2 - 0.11 12.2 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EAU87363.2 - 0.16 11.6 0.2 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 NTPase F-box-like PF12937.2 EAU87364.1 - 0.011 15.4 0.0 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 F-box-like Neurensin PF14927.1 EAU87365.2 - 0.27 10.5 3.4 10 5.4 0.1 2.6 2 1 0 2 2 2 0 Neurensin PepSY_TM_2 PF13703.1 EAU87366.1 - 1.7 8.8 6.7 5.9 7.1 1.9 2.9 2 1 1 3 3 3 0 PepSY-associated TM helix zf-DHHC PF01529.15 EAU87367.1 - 0.094 12.1 0.8 0.75 9.1 1.5 1.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2614 PF11023.3 EAU87367.1 - 0.29 10.9 1.4 7.8 6.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Neurensin PF14927.1 EAU87367.1 - 0.58 9.5 2.5 13 5.1 1.4 3.1 2 1 0 2 2 2 0 Neurensin DUF3040 PF11239.3 EAU87367.1 - 9.2 6.3 15.2 3.8 7.6 0.2 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) Oxidored_q3 PF00499.15 EAU87368.2 - 0.00079 19.2 5.5 0.0011 18.7 3.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CTP_transf_1 PF01148.15 EAU87368.2 - 0.028 14.0 3.9 0.04 13.5 2.7 1.2 1 0 0 1 1 1 0 Cytidylyltransferase family Transport_MerF PF11431.3 EAU87368.2 - 0.39 10.4 9.2 2.9 7.5 3.9 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF Sensor PF13796.1 EAU87368.2 - 0.51 9.9 6.6 4.3 6.9 0.3 2.3 2 0 0 2 2 2 0 Putative sensor Halogen_Hydrol PF10112.4 EAU87368.2 - 2 7.7 4.7 1.1 8.6 0.5 2.0 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Tic20 PF09685.5 EAU87368.2 - 8.3 6.4 14.3 0.18 11.7 0.9 2.6 2 1 0 2 2 2 0 Tic20-like protein STE3 PF02076.10 EAU87370.1 - 5.8e-106 353.6 20.2 7e-106 353.4 14.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor bPH_4 PF06713.6 EAU87370.1 - 0.15 11.9 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial PH domain Pheromone PF08015.6 EAU87371.1 - 0.00022 21.9 0.5 0.0003 21.5 0.3 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EAU87373.1 - 2.1e-09 38.0 1.5 4.6e-09 36.9 1.0 1.6 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EAU87374.1 - 2.2e-09 38.0 0.4 2e-08 34.9 0.3 1.9 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EAU87375.2 - 9.2e-10 39.2 0.4 1.1e-09 38.9 0.3 1.1 1 0 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EAU87376.1 - 2e-11 44.5 0.3 2.3e-11 44.3 0.2 1.0 1 0 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.10 EAU87378.2 - 3.8e-106 354.3 14.9 4.6e-106 354.0 10.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor EAF PF09816.4 EAU87378.2 - 0.069 13.1 0.8 1.2 9.0 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription elongation factor Cytochrom_B558a PF05038.8 EAU87378.2 - 0.26 10.8 3.3 0.82 9.2 0.2 2.8 3 1 0 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit Multi_Drug_Res PF00893.14 EAU87378.2 - 0.32 11.4 4.2 0.4 11.1 0.8 2.6 2 2 1 3 3 3 0 Small Multidrug Resistance protein MFS_1 PF07690.11 EAU87380.2 - 2.7e-35 121.7 64.8 2.4e-34 118.6 17.7 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EAU87380.2 - 4.9e-20 71.2 19.0 7.8e-20 70.6 13.2 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EAU87380.2 - 1.3e-11 43.7 13.9 1.3e-11 43.7 9.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3483 PF11982.3 EAU87380.2 - 0.087 12.1 5.2 0.48 9.6 3.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3483) Abhydrolase_3 PF07859.8 EAU87381.2 - 9e-19 67.8 0.0 1.3e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU87381.2 - 2.4e-17 62.6 0.0 3.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EAU87381.2 - 3.1e-05 23.9 0.0 6.3e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU87381.2 - 0.0035 17.1 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EAU87382.1 - 2.4e-14 53.4 0.0 3.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU87382.1 - 8.8e-11 41.0 0.0 9.5e-11 40.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EAU87382.1 - 2.8e-05 24.0 0.1 4.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU87382.1 - 0.006 16.3 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EAU87382.1 - 0.042 14.0 0.1 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain MFS_1 PF07690.11 EAU87383.2 - 1.8e-22 79.5 46.0 4.3e-20 71.7 30.8 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU87383.2 - 1.9e-09 36.6 6.6 1.9e-09 36.6 4.6 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EAU87383.2 - 0.017 13.3 16.8 3.1 5.8 12.3 3.2 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF962 PF06127.6 EAU87383.2 - 0.026 14.4 3.2 0.58 10.0 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF962) PCI PF01399.22 EAU87386.1 - 1.6e-09 38.0 0.2 5.1e-09 36.3 0.0 2.0 3 0 0 3 3 3 1 PCI domain DUF2424 PF10340.4 EAU87388.2 - 1.7e-17 63.1 0.0 2.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EAU87388.2 - 3.3e-15 56.2 0.0 4.9e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EAU87389.2 - 1.9e-18 66.2 37.9 2.5e-09 36.3 4.5 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU87389.2 - 3.3e-12 45.7 18.9 1.6e-11 43.4 13.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EAU87390.2 - 3.8e-06 26.2 0.0 6.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87390.2 - 0.098 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4658 PF15555.1 EAU87390.2 - 4.1 7.2 6.9 9 6.1 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Pkinase PF00069.20 EAU87391.2 - 0.0015 17.7 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain STE3 PF02076.10 EAU87392.2 - 4.3e-99 331.1 14.7 5.2e-99 330.8 10.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EAU87394.2 - 6.5e-34 117.3 13.8 4.2e-26 91.6 3.4 2.1 1 1 1 2 2 2 2 Pheromone A receptor Beta_elim_lyase PF01212.16 EAU87396.2 - 0.0036 16.5 0.7 0.0051 15.9 0.5 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3391 PF11871.3 EAU87396.2 - 0.016 15.3 5.1 0.025 14.7 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) zf-C4H2 PF10146.4 EAU87396.2 - 0.19 11.7 14.0 0.25 11.3 9.7 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein ERM PF00769.14 EAU87396.2 - 0.24 10.9 22.0 0.37 10.2 15.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family OmpH PF03938.9 EAU87396.2 - 0.28 11.1 11.2 0.44 10.4 7.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 EAU87396.2 - 0.55 9.1 2.4 0.71 8.7 1.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2264 PF10022.4 EAU87396.2 - 0.75 8.3 3.7 0.98 7.9 2.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) ISG65-75 PF11727.3 EAU87396.2 - 0.81 8.6 9.0 1.1 8.2 6.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein PCEMA1 PF07418.6 EAU87396.2 - 1.3 8.3 8.5 1.6 8.0 5.9 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF3513 PF12026.3 EAU87396.2 - 1.3 8.5 6.6 1.8 8.0 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) TipAS PF07739.8 EAU87396.2 - 6.1 7.1 18.3 7.5 6.9 1.1 2.9 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Prefoldin PF02996.12 EAU87397.1 - 2.2e-26 91.8 0.1 2e-25 88.7 0.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit RRM_1 PF00076.17 EAU87398.1 - 1e-78 258.9 0.1 1.2e-20 72.9 0.0 5.7 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU87398.1 - 1.9e-62 207.1 0.1 1.6e-16 60.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU87398.1 - 2.3e-34 117.0 0.0 1.3e-09 37.7 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAU87398.1 - 0.00029 20.5 0.0 21 4.9 0.0 4.9 4 1 0 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 EAU87398.1 - 0.00044 19.9 0.0 0.34 10.7 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 EAU87398.1 - 0.0022 17.9 0.0 6.4 6.8 0.0 4.1 4 0 0 4 4 4 1 RNA recognition motif 2 DUF3343 PF11823.3 EAU87398.1 - 0.091 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) Myb_DNA-binding PF00249.26 EAU87399.2 - 7.3e-14 51.5 0.0 4.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAU87399.2 - 1e-09 38.3 0.0 1.7e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DNA_pack_N PF02500.10 EAU87399.2 - 0.34 10.4 5.9 0.042 13.3 1.0 1.6 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus HrpB7 PF09486.5 EAU87403.2 - 0.0025 17.7 2.0 0.0046 16.8 1.4 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Med4 PF10018.4 EAU87403.2 - 0.0042 16.5 2.2 0.0099 15.2 1.5 1.6 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 FemAB PF02388.11 EAU87403.2 - 0.024 13.3 0.1 0.034 12.8 0.1 1.2 1 0 0 1 1 1 0 FemAB family DUF1515 PF07439.6 EAU87403.2 - 0.029 14.1 1.3 0.06 13.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF3450 PF11932.3 EAU87403.2 - 0.054 12.7 2.0 0.099 11.8 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6 PF04111.7 EAU87403.2 - 0.43 9.5 6.0 0.75 8.7 4.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PEARLI-4 PF05278.7 EAU87403.2 - 1.2 8.4 7.3 2.5 7.3 5.1 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) UPF0542 PF15086.1 EAU87403.2 - 1.9 8.2 5.5 7 6.4 3.8 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DivIC PF04977.10 EAU87403.2 - 5.5 6.5 7.2 1.8 8.1 2.6 2.0 2 0 0 2 2 2 0 Septum formation initiator Choline_transpo PF04515.7 EAU87404.1 - 0.013 14.3 0.2 0.024 13.3 0.1 1.3 1 0 0 1 1 1 0 Plasma-membrane choline transporter Sigma_reg_N PF13800.1 EAU87404.1 - 0.018 15.0 1.1 0.041 13.8 0.1 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SNF2_N PF00176.18 EAU87406.2 - 4.6e-43 147.1 0.0 9.2e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1687 PF07955.6 EAU87408.2 - 6e-13 48.9 0.0 7.4e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) EAP30 PF04157.11 EAU87410.2 - 2.6e-37 128.1 0.0 3.3e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EAU87410.2 - 1.6e-20 72.6 0.0 3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EAU87410.2 - 0.00011 21.2 5.4 0.021 13.8 1.3 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EAU87410.2 - 0.012 15.4 6.2 0.11 12.3 0.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EAU87410.2 - 8.1 5.7 9.1 7.6 5.8 1.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rhodanese PF00581.15 EAU87411.1 - 1.8e-06 28.2 0.0 7.4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain Mito_carr PF00153.22 EAU87412.2 - 4e-59 196.3 5.3 2.7e-20 71.8 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein SRP9-21 PF05486.7 EAU87413.1 - 9.3e-19 66.9 0.5 1.2e-18 66.6 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.12 EAU87413.1 - 0.065 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Rrn6 PF10214.4 EAU87413.1 - 0.43 8.6 2.6 0.38 8.8 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Hydrophobin PF01185.13 EAU87414.1 - 8.9e-07 29.2 1.1 0.00028 21.2 0.0 2.2 1 1 1 2 2 2 2 Fungal hydrophobin Hydrophobin PF01185.13 EAU87415.2 - 5.2e-20 71.6 6.5 8e-20 71.0 4.5 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Herpes_gE PF02480.11 EAU87416.2 - 0.012 13.9 0.0 0.015 13.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EAU87416.2 - 0.1 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.8 EAU87416.2 - 0.16 10.5 0.7 0.23 10.0 0.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein GRA6 PF05084.8 EAU87418.1 - 0.0067 15.9 4.3 0.0095 15.4 3.0 1.2 1 0 0 1 1 1 1 Granule antigen protein (GRA6) DUF1180 PF06679.7 EAU87418.1 - 0.03 14.1 0.7 0.03 14.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF1628 PF07790.6 EAU87418.1 - 0.041 14.6 0.4 0.077 13.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Synaptobrevin PF00957.16 EAU87418.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Synaptobrevin GRP PF07172.6 EAU87418.1 - 0.16 12.4 8.8 0.28 11.6 6.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family Pol_alpha_B_N PF08418.5 EAU87418.1 - 0.2 11.1 1.0 0.24 10.9 0.7 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Plasmodium_Vir PF05795.6 EAU87419.1 - 2 7.5 3.7 2.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Trypan_PARP PF05887.6 EAU87421.1 - 1.8 8.3 12.3 0.19 11.5 4.0 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Shisa PF13908.1 EAU87421.1 - 2.7 8.1 5.3 0.89 9.7 0.0 2.5 2 2 0 2 2 2 0 Wnt and FGF inhibitory regulator Hydrophobin PF01185.13 EAU87422.1 - 2.9e-24 85.3 8.2 3.7e-24 84.9 5.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Defensin_beta PF00711.14 EAU87422.1 - 1.7 8.6 7.6 0.31 10.9 0.6 2.3 2 0 0 2 2 2 0 Beta defensin Hydrophobin PF01185.13 EAU87423.1 - 6.8e-23 80.9 8.3 8.7e-23 80.5 5.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin IglC PF11550.3 EAU87423.1 - 0.19 10.9 1.6 0.64 9.2 0.3 1.8 1 1 1 2 2 2 0 Intracellular growth locus C protein Hydrophobin PF01185.13 EAU87424.1 - 9.6e-26 90.0 10.7 1.2e-25 89.7 7.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EAU87425.1 - 9.4e-26 90.0 9.3 1.1e-25 89.8 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EAU87426.1 - 1.3e-21 76.7 10.4 1.7e-21 76.4 7.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF605 PF04652.11 EAU87428.2 - 0.3 10.4 6.2 0.3 10.4 4.3 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_61 PF03443.9 EAU87430.2 - 8.7e-54 182.6 1.2 2.9e-53 180.9 0.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAU87430.2 - 1.1e-09 37.7 12.1 1.1e-09 37.7 8.4 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU87430.2 - 0.042 13.8 2.0 0.082 12.9 1.4 1.5 1 0 0 1 1 1 0 Toxin 7 zf-DHHC PF01529.15 EAU87431.2 - 4.4e-34 117.3 16.8 2.1e-33 115.1 11.6 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase HemY_N PF07219.8 EAU87431.2 - 0.11 12.0 0.1 9.3 5.8 0.0 2.7 2 0 0 2 2 2 0 HemY protein N-terminus DUF939 PF06081.6 EAU87431.2 - 0.14 12.0 2.6 0.29 10.9 1.8 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) Oxidored_q2 PF00420.19 EAU87431.2 - 1 8.9 4.1 0.47 10.0 0.7 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Glyco_hydro_61 PF03443.9 EAU87435.1 - 5.4e-59 199.6 0.0 6.2e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EAU87436.2 - 7.2e-57 192.6 0.0 8.3e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N PF08240.7 EAU87437.2 - 6.8e-29 99.8 0.7 1.3e-28 98.8 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU87437.2 - 5.1e-15 55.1 0.0 1.1e-14 54.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU87437.2 - 0.00056 20.8 0.0 0.001 19.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase IncA PF04156.9 EAU87440.1 - 0.77 9.3 11.0 1.4 8.5 7.6 1.4 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EAU87440.1 - 1.7 7.5 7.4 2.7 6.9 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EAU87442.1 - 0.014 15.7 2.4 0.014 15.7 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3584 PF12128.3 EAU87442.1 - 0.054 10.8 3.9 0.078 10.3 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EAU87442.1 - 0.11 11.1 3.4 0.16 10.5 2.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1247 PF06851.6 EAU87442.1 - 0.13 11.9 1.0 0.22 11.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) adh_short PF00106.20 EAU87444.1 - 7.5e-18 65.0 2.4 1e-17 64.5 1.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU87444.1 - 7.8e-09 35.4 1.8 1.3e-08 34.7 1.2 1.3 1 0 0 1 1 1 1 KR domain Glyco_trans_4_4 PF13579.1 EAU87444.1 - 0.017 15.2 1.1 0.062 13.4 0.7 2.0 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain YjeF_N PF03853.10 EAU87444.1 - 0.018 14.6 0.1 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 EAU87444.1 - 0.024 14.6 0.3 0.092 12.7 0.2 2.1 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EAU87444.1 - 0.026 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phosphorylase PF00343.15 EAU87445.2 - 2e-294 978.0 0.0 2.4e-294 977.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.20 EAU87446.1 - 2.6e-58 197.2 0.0 4.1e-58 196.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87446.1 - 8.6e-30 103.6 0.0 6.7e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU87446.1 - 0.001 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GspH PF12019.3 EAU87446.1 - 0.028 14.5 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Type II transport protein GspH Seadorna_VP7 PF07387.6 EAU87446.1 - 0.065 12.0 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.27 EAU87447.2 - 1.5e-22 78.5 4.3 2.2e-08 33.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat STE PF02200.11 EAU87448.2 - 1.3e-50 170.1 0.1 2.2e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EAU87448.2 - 7.7e-11 41.6 12.9 1.6e-05 24.9 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU87448.2 - 2.9e-10 39.7 9.5 4.5e-05 23.4 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU87448.2 - 3.1e-08 33.5 13.2 4.2e-07 29.9 3.8 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EAU87448.2 - 0.053 13.6 4.7 1.7 8.9 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAU87448.2 - 0.054 13.4 0.6 0.15 11.9 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EAU87448.2 - 0.73 9.9 3.3 1.8 8.7 1.3 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EAU87448.2 - 0.98 9.7 6.3 1.5 9.1 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EAU87448.2 - 2.1 8.1 7.3 0.38 10.5 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger DUF4366 PF14283.1 EAU87449.2 - 0.032 13.6 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tad PF13400.1 EAU87449.2 - 0.06 13.3 2.8 0.12 12.4 2.0 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF1378 PF07125.6 EAU87449.2 - 0.18 11.7 0.1 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) PepSY_TM_2 PF13703.1 EAU87450.2 - 0.034 14.3 0.2 0.052 13.7 0.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix DUF1049 PF06305.6 EAU87450.2 - 0.044 13.2 0.6 0.08 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Gram_pos_anchor PF00746.16 EAU87450.2 - 0.22 11.3 1.3 0.38 10.6 0.9 1.3 1 0 0 1 1 1 0 Gram positive anchor Rax2 PF12768.2 EAU87451.2 - 0.026 13.7 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.1 EAU87451.2 - 0.04 13.6 0.9 0.16 11.6 0.0 2.2 2 1 0 2 2 2 0 TMEM154 protein family DUF4131 PF13567.1 EAU87451.2 - 0.28 10.5 1.3 0.58 9.5 0.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.16 EAU87452.2 - 1.5e-73 247.0 0.0 1.7e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT_2 PF13279.1 EAU87456.1 - 0.00013 22.4 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.20 EAU87457.2 - 0.014 14.5 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain YwqJ-deaminase PF14431.1 EAU87460.2 - 2.1e-08 34.0 1.8 0.0055 16.5 0.1 2.4 2 0 0 2 2 2 2 YwqJ-like deaminase zf-AD PF07776.10 EAU87460.2 - 0.092 12.7 1.1 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Unstab_antitox PF09720.5 EAU87462.2 - 0.85 9.3 11.8 31 4.3 0.1 5.6 6 0 0 6 6 6 0 Putative addiction module component MARVEL PF01284.18 EAU87463.1 - 7.4e-05 22.5 8.2 0.0041 16.9 2.7 2.2 2 0 0 2 2 2 2 Membrane-associating domain DUF3290 PF11694.3 EAU87463.1 - 0.0065 16.2 0.3 0.012 15.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) COX14 PF14880.1 EAU87463.1 - 0.34 10.5 1.6 0.95 9.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Rab5ip PF07019.7 EAU87463.1 - 1.3 9.2 7.9 1.6 8.9 0.3 2.7 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Ni_hydr_CYTB PF01292.15 EAU87463.1 - 1.4 8.2 13.5 98 2.2 9.1 2.4 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Ctr PF04145.10 EAU87464.1 - 5.2e-26 91.4 0.6 7.1e-26 90.9 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TraL PF07178.6 EAU87464.1 - 2.5 8.1 4.9 1.1 9.3 0.1 2.4 3 0 0 3 3 3 0 TraL protein Methyltransf_22 PF13383.1 EAU87466.2 - 2.4e-27 96.0 0.0 2.9e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EAU87466.2 - 3.3e-07 30.4 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain CAP59_mtransfer PF11735.3 EAU87467.2 - 1.9e-66 223.7 0.0 2.4e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Tubulin_3 PF14881.1 EAU87470.2 - 2.9e-31 108.3 0.0 3.9e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 EAU87470.2 - 0.088 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Gti1_Pac2 PF09729.4 EAU87471.1 - 7.8e-29 100.6 0.2 2.2e-26 92.7 0.1 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family HsbA PF12296.3 EAU87472.1 - 8.3e-08 32.1 0.2 1.6e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 Hydrophobic surface binding protein A Pkinase_Tyr PF07714.12 EAU87473.2 - 1.1e-51 175.4 0.0 1.6e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU87473.2 - 7.6e-44 149.8 0.0 5.4e-31 107.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EAU87473.2 - 0.00032 20.1 0.2 0.0042 16.4 0.0 2.4 3 0 0 3 3 3 1 RIO1 family Kdo PF06293.9 EAU87473.2 - 0.00064 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU87473.2 - 0.004 16.9 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RPT PF13446.1 EAU87473.2 - 0.015 14.7 0.1 0.037 13.4 0.1 1.6 1 0 0 1 1 1 0 A repeated domain in UCH-protein FAT PF02259.18 EAU87473.2 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 FAT domain Peptidase_M43 PF05572.8 EAU87477.2 - 8.9e-17 61.1 0.0 1.5e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU87477.2 - 6.3e-05 22.9 0.0 0.00018 21.5 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU87477.2 - 0.00088 19.8 0.0 0.0037 17.7 0.0 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU87477.2 - 0.0012 18.9 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU87477.2 - 0.0019 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87477.2 - 0.039 13.6 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M54 PF07998.6 EAU87477.2 - 0.18 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 p450 PF00067.17 EAU87478.1 - 2.1e-69 234.2 0.0 2.9e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M43 PF05572.8 EAU87479.1 - 2.5e-19 69.3 0.0 4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU87479.1 - 4.9e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU87479.1 - 2.3e-05 24.8 0.0 4.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU87479.1 - 3.7e-05 23.8 0.0 7.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU87479.1 - 0.00057 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EAU87479.1 - 0.0096 15.2 0.3 0.018 14.3 0.1 1.5 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EAU87479.1 - 0.028 14.1 0.2 0.052 13.2 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M7 PF02031.11 EAU87479.1 - 0.071 12.8 0.5 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family ABC_tran PF00005.22 EAU87480.2 - 2.3e-53 180.1 0.0 1.3e-30 106.4 0.0 2.9 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAU87480.2 - 1.1e-29 103.7 18.7 1.1e-15 57.7 2.1 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 EAU87480.2 - 1.2e-07 32.0 0.1 1.1 9.2 0.0 4.3 3 1 1 4 4 4 2 AAA domain T2SE PF00437.15 EAU87480.2 - 1.2e-07 30.9 0.2 0.0012 17.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 EAU87480.2 - 7.5e-07 28.5 0.0 0.0066 15.7 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAU87480.2 - 1.7e-06 27.4 0.4 0.035 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EAU87480.2 - 7.6e-06 25.4 0.1 0.035 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EAU87480.2 - 2.4e-05 24.7 4.9 0.00039 20.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EAU87480.2 - 0.0004 20.4 0.8 1.5 8.7 0.2 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EAU87480.2 - 0.0022 17.4 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EAU87480.2 - 0.0064 16.6 0.8 13 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EAU87480.2 - 0.019 14.0 0.1 1.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 EAU87480.2 - 0.023 14.5 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 EAU87480.2 - 0.044 13.4 0.3 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 EAU87480.2 - 0.056 13.2 0.1 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Dynamin family DUF258 PF03193.11 EAU87480.2 - 0.14 11.3 0.1 16 4.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EAU87480.2 - 0.16 11.6 0.9 7.8 6.1 0.0 3.3 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.1 EAU87480.2 - 0.27 11.1 0.2 4.6 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain TPR_11 PF13414.1 EAU87481.2 - 5.5e-10 38.7 3.7 0.026 14.1 0.0 5.7 5 1 1 6 6 6 3 TPR repeat TPR_2 PF07719.12 EAU87481.2 - 3.8e-06 26.3 5.9 0.59 10.1 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU87481.2 - 5.5e-06 25.7 5.5 0.13 12.1 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU87481.2 - 2.5e-05 23.6 1.2 6.3 6.5 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU87481.2 - 3.2e-05 24.1 7.9 0.8 10.5 0.3 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU87481.2 - 4.2e-05 23.3 7.5 0.13 12.1 0.8 4.4 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU87481.2 - 6.5e-05 23.1 0.6 8.4 6.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU87481.2 - 0.00029 21.4 5.6 32 5.3 0.1 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU87481.2 - 0.002 18.4 1.8 58 4.4 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EAU87481.2 - 0.0026 17.8 0.2 11 6.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU87481.2 - 0.0035 17.0 0.5 3.7 7.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU87482.2 - 4.5e-05 23.3 0.3 4.5e-05 23.3 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAU87482.2 - 0.00023 20.7 1.7 0.034 13.7 0.3 2.6 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 EAU87482.2 - 0.002 17.7 1.3 0.22 11.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU87482.2 - 0.0057 16.3 3.7 0.72 9.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU87482.2 - 0.011 15.3 0.3 0.092 12.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU87482.2 - 0.26 11.3 6.2 0.46 10.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Totivirus_coat PF05518.6 EAU87482.2 - 2.3 5.9 4.4 4.8 4.8 3.1 1.4 1 0 0 1 1 1 0 Totivirus coat protein PAP1 PF08601.5 EAU87482.2 - 2.4 7.7 6.8 4.3 6.9 4.7 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Pkinase PF00069.20 EAU87483.2 - 0.03 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 EAU87484.2 - 0.0045 16.1 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87484.2 - 0.18 10.8 0.0 0.43 9.6 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase p450 PF00067.17 EAU87485.1 - 2e-68 231.0 0.0 2.9e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MARVEL PF01284.18 EAU87486.1 - 7.2e-06 25.8 11.4 1.1e-05 25.2 7.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain FA_desaturase PF00487.19 EAU87486.1 - 0.46 9.8 9.8 0.85 8.9 6.8 1.5 1 1 0 1 1 1 0 Fatty acid desaturase SieB PF14163.1 EAU87486.1 - 0.69 9.4 2.3 3.4 7.2 1.7 1.9 2 0 0 2 2 2 0 Superinfection exclusion protein B Peptidase_M43 PF05572.8 EAU87488.2 - 4.2e-18 65.4 0.4 6.4e-18 64.8 0.3 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU87488.2 - 0.00027 20.9 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU87488.2 - 0.00049 20.6 0.2 0.0019 18.6 0.1 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EAU87488.2 - 0.0015 17.8 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.1 EAU87488.2 - 0.0042 17.1 0.2 0.0064 16.5 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87488.2 - 0.016 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_4 PF13583.1 EAU87488.2 - 0.026 14.0 0.6 0.047 13.2 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EAU87488.2 - 0.17 10.7 0.2 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF1025 PF06262.6 EAU87488.2 - 0.8 9.5 2.7 5.6 6.8 0.7 2.8 3 1 1 4 4 4 0 Possibl zinc metallo-peptidase Hid1 PF12722.2 EAU87490.2 - 6.5 4.3 6.3 7.7 4.0 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 EAU87490.2 - 7 5.5 8.2 9.6 5.0 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 EAU87490.2 - 7.6 6.5 26.9 14 5.6 18.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EAU87490.2 - 8.9 4.2 20.2 10 4.0 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.20 EAU87492.1 - 5.9e-12 45.2 0.0 7.4e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU87492.1 - 3.6e-05 23.6 0.0 9.6e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EAU87492.1 - 0.00073 18.6 0.0 0.0016 17.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAU87492.1 - 0.00093 18.3 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EAU87492.1 - 0.0034 16.7 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EAU87492.1 - 0.0036 16.9 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EAU87492.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EAU87492.1 - 0.18 10.7 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like MIP-T3 PF10243.4 EAU87495.2 - 1.9 6.8 8.0 3.5 5.9 5.4 1.4 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 OTU PF02338.14 EAU87496.1 - 9e-16 58.5 0.1 1.6e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease PRP3 PF08572.5 EAU87496.1 - 0.00079 18.8 2.0 0.0016 17.8 1.4 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) Peptidase_C65 PF10275.4 EAU87496.1 - 0.026 13.8 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain DUF1996 PF09362.5 EAU87499.2 - 2.1e-68 230.5 0.0 2.6e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EAU87500.2 - 0.00016 21.4 0.3 0.00021 21.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) F-box-like PF12937.2 EAU87502.2 - 1.8e-05 24.3 0.3 0.00036 20.1 0.1 3.1 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 EAU87503.2 - 0.98 9.2 10.1 0.2 11.4 1.9 3.5 4 1 0 4 4 4 0 F-box-like F-box-like PF12937.2 EAU87506.2 - 1e-07 31.5 0.7 5.6e-07 29.1 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAU87506.2 - 0.21 11.2 3.9 0.48 10.0 0.6 3.0 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Glyco_transf_20 PF00982.16 EAU87507.2 - 1.7e-133 445.6 0.0 2.4e-133 445.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EAU87507.2 - 2.3e-21 75.8 0.0 4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EAU87507.2 - 0.042 13.3 0.0 0.093 12.2 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain F-box-like PF12937.2 EAU87508.2 - 7.1e-10 38.4 0.1 1.7e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 EAU87508.2 - 0.1 13.1 2.3 0.38 11.3 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat F-box PF00646.28 EAU87508.2 - 0.49 10.1 3.4 1 9.0 0.2 3.1 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 EAU87511.2 - 2e-07 30.5 0.0 2.9e-05 23.7 0.0 3.0 2 1 0 2 2 2 1 F-box-like AalphaY_MDB PF04611.7 EAU87511.2 - 0.0013 18.5 0.0 0.006 16.4 0.0 2.0 2 0 0 2 2 2 1 Mating type protein A alpha Y mating type dependent binding region AAA_12 PF13087.1 EAU87511.2 - 0.0086 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain F-box-like PF12937.2 EAU87512.2 - 3.5e-07 29.8 0.0 7.3e-06 25.6 0.0 2.9 2 1 0 2 2 2 1 F-box-like Aldo_ket_red PF00248.16 EAU87515.1 - 3.6e-43 147.4 0.0 4.5e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Isochorismatase PF00857.15 EAU87516.2 - 8.4e-18 64.9 0.2 1e-17 64.6 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF4436 PF14494.1 EAU87517.2 - 0.002 17.4 0.8 0.0027 17.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) MT-A70 PF05063.9 EAU87518.2 - 1.7e-39 135.1 0.0 3.7e-39 134.0 0.0 1.5 1 1 0 1 1 1 1 MT-A70 Cons_hypoth95 PF03602.10 EAU87518.2 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Kelch_4 PF13418.1 EAU87519.2 - 1.5e-42 143.1 10.3 2.3e-09 36.8 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EAU87519.2 - 2.3e-34 116.7 17.4 4.1e-07 29.9 0.0 8.0 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EAU87519.2 - 1.2e-33 114.4 3.2 7.3e-07 29.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EAU87519.2 - 8.6e-30 101.6 9.0 7.1e-05 22.8 0.1 6.7 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EAU87519.2 - 1.7e-28 97.9 2.2 7.6e-05 22.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EAU87519.2 - 4.1e-27 92.8 4.3 0.00027 20.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif DUF2413 PF10310.4 EAU87519.2 - 0.56 8.9 1.2 0.66 8.7 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2413) KAR9 PF08580.5 EAU87519.2 - 9.4 4.3 6.2 12 4.0 4.3 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_C14 PF00656.17 EAU87520.2 - 1.5e-15 57.5 0.0 6.4e-15 55.5 0.0 1.9 1 1 0 1 1 1 1 Caspase domain Zein-binding PF04576.10 EAU87520.2 - 0.016 15.3 3.4 0.036 14.1 2.4 1.5 1 0 0 1 1 1 0 Zein-binding Fez1 PF06818.10 EAU87520.2 - 0.017 15.1 1.4 0.033 14.2 1.0 1.4 1 0 0 1 1 1 0 Fez1 HALZ PF02183.13 EAU87520.2 - 4.4 7.1 5.7 4.2 7.1 0.5 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Glyco_hydro_28 PF00295.12 EAU87521.2 - 6.6e-41 140.3 0.3 1e-40 139.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Mucin PF01456.12 EAU87523.1 - 0.0075 16.0 11.8 3 7.6 0.0 2.5 2 0 0 2 2 2 2 Mucin-like glycoprotein Noc2 PF03715.8 EAU87524.1 - 7.4e-95 317.2 0.0 3.6e-94 314.9 0.0 2.0 2 0 0 2 2 2 1 Noc2p family BUD22 PF09073.5 EAU87524.1 - 2.3 7.1 33.8 4 6.4 23.4 1.3 1 0 0 1 1 1 0 BUD22 DUF4255 PF14065.1 EAU87525.1 - 0.064 12.6 0.1 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) DUF433 PF04255.9 EAU87525.1 - 0.1 12.0 0.1 0.53 9.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF433) HSP70 PF00012.15 EAU87526.2 - 0.0089 13.9 0.0 0.053 11.4 0.0 2.1 2 1 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 EAU87526.2 - 0.093 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family ALO PF04030.9 EAU87527.2 - 9.7e-77 258.0 0.9 1.2e-76 257.7 0.6 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EAU87527.2 - 5e-29 100.5 0.1 7.4e-29 99.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain UPF0029 PF01205.14 EAU87527.2 - 0.06 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 UQ_con PF00179.21 EAU87528.2 - 6.3e-14 51.5 0.0 7.1e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RNA_pol_Rpb2_6 PF00562.23 EAU87529.2 - 1.3e-118 396.1 0.2 9.9e-118 393.2 0.1 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EAU87529.2 - 1.1e-54 184.4 0.3 2.4e-54 183.3 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EAU87529.2 - 2.1e-29 102.2 0.1 5.4e-29 100.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EAU87529.2 - 2.4e-28 98.2 0.1 7.4e-28 96.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EAU87529.2 - 1.1e-23 82.7 2.7 1.3e-23 82.5 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EAU87529.2 - 5.3e-21 74.1 0.4 1.6e-20 72.5 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EAU87529.2 - 2.1e-12 46.7 0.2 6.9e-12 45.1 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 UQ_con PF00179.21 EAU87530.2 - 3.7e-46 156.0 0.0 4.2e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAU87530.2 - 0.0008 19.1 0.0 0.0055 16.4 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic E2 family B SNF2_N PF00176.18 EAU87531.2 - 1.3e-50 171.8 0.1 2e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EAU87531.2 - 0.0051 16.6 0.1 0.0051 16.6 0.0 2.5 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.10 EAU87531.2 - 0.025 14.4 0.1 0.025 14.4 0.0 3.9 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit Peptidase_C65 PF10275.4 EAU87532.2 - 3.5e-48 164.0 0.0 5.5e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain K1377 PF15352.1 EAU87532.2 - 0.018 13.0 1.9 0.024 12.6 1.3 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy DUF4610 PF15384.1 EAU87532.2 - 0.026 14.0 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) OTU PF02338.14 EAU87532.2 - 0.028 14.9 0.0 1.3 9.5 0.0 2.7 3 0 0 3 3 3 0 OTU-like cysteine protease DUF3414 PF11894.3 EAU87534.1 - 2e-261 870.4 0.0 2.8e-261 869.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Chromo PF00385.19 EAU87535.2 - 2.2e-09 36.8 1.2 3.3e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1136 PF06582.7 EAU87536.2 - 0.032 13.9 0.0 0.089 12.4 0.0 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) DUF3287 PF11690.3 EAU87537.1 - 0.25 11.4 11.1 0.67 10.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) DUF4140 PF13600.1 EAU87537.1 - 8.4 6.9 25.8 1.7 9.1 2.1 3.6 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) MMR_HSR1 PF01926.18 EAU87538.2 - 4.4e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU87538.2 - 1.5e-05 24.2 0.1 3.1e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 AIG1 family Septin PF00735.13 EAU87538.2 - 2.3e-05 23.5 0.1 9e-05 21.6 0.0 1.9 2 1 0 2 2 2 1 Septin AAA_24 PF13479.1 EAU87538.2 - 0.00068 19.2 0.4 0.0012 18.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF3829 PF12889.2 EAU87538.2 - 0.0028 16.9 5.3 0.0043 16.2 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) FeoB_N PF02421.13 EAU87538.2 - 0.0049 16.1 0.0 0.012 14.9 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EAU87538.2 - 0.011 15.9 0.1 0.045 13.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain IncA PF04156.9 EAU87538.2 - 0.011 15.3 1.6 0.015 14.8 1.1 1.2 1 0 0 1 1 1 0 IncA protein DUF258 PF03193.11 EAU87538.2 - 0.011 14.8 0.2 0.031 13.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EAU87538.2 - 0.017 15.3 0.4 0.039 14.1 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EAU87538.2 - 0.024 15.1 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 EAU87538.2 - 0.049 13.6 2.4 0.093 12.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EAU87538.2 - 0.066 12.5 0.5 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Katanin_con80 PF13925.1 EAU87538.2 - 0.13 12.0 1.2 0.22 11.2 0.3 1.7 2 0 0 2 2 2 0 con80 domain of Katanin AAA_17 PF13207.1 EAU87538.2 - 0.14 12.9 1.3 1.2 9.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF106 PF01956.11 EAU87538.2 - 0.14 11.6 2.3 0.25 10.8 1.6 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3987 PF13148.1 EAU87538.2 - 0.15 10.5 5.1 2 6.9 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_18 PF13238.1 EAU87538.2 - 0.19 12.0 1.6 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EAU87538.2 - 0.23 11.1 2.9 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 EAU87538.2 - 0.3 10.8 7.6 5.5 6.7 0.2 3.3 2 2 1 3 3 3 0 Dynamin family DUF342 PF03961.8 EAU87538.2 - 0.69 8.2 5.5 1 7.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TSC22 PF01166.13 EAU87538.2 - 0.78 9.7 5.2 10 6.1 0.1 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family AAA_11 PF13086.1 EAU87538.2 - 1.2 8.6 4.4 24 4.4 3.1 2.3 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 EAU87538.2 - 7.7 6.5 11.3 2.3 8.2 2.2 2.4 1 1 1 2 2 2 0 bZIP transcription factor Antimicrobial10 PF08105.6 EAU87539.1 - 4.2 7.0 4.8 2.6 7.7 1.7 1.8 2 0 0 2 2 2 0 Metchnikowin family zf-MYND PF01753.13 EAU87540.2 - 2.5e-06 27.2 16.9 0.00026 20.8 2.5 3.6 3 1 1 4 4 4 2 MYND finger zf-Mss51 PF13824.1 EAU87540.2 - 0.57 10.0 2.5 4.9 7.0 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 KNOX1 PF03790.8 EAU87542.2 - 6.5 6.1 6.1 0.5 9.7 0.2 2.1 2 0 0 2 2 2 0 KNOX1 domain AIG1 PF04548.11 EAU87543.2 - 2.6e-11 43.0 0.0 2.6e-11 43.0 0.0 2.5 3 0 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.18 EAU87543.2 - 3e-10 40.0 0.0 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAU87543.2 - 2.5e-07 30.0 0.0 7.9e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EAU87543.2 - 2.3e-06 26.9 0.3 1.7e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EAU87543.2 - 8.6e-06 25.0 0.0 2.9e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.18 EAU87543.2 - 1e-05 25.4 8.9 0.00021 21.1 0.2 3.8 2 2 2 4 4 4 2 Dynamin family ABC_tran PF00005.22 EAU87543.2 - 0.00072 19.8 0.0 0.00072 19.8 0.0 3.4 3 2 0 3 3 3 1 ABC transporter SRPRB PF09439.5 EAU87543.2 - 0.0013 18.0 0.0 0.0013 18.0 0.0 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EAU87543.2 - 0.0027 17.1 0.3 0.0064 16.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 EAU87543.2 - 0.0028 18.1 0.0 0.01 16.3 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EAU87543.2 - 0.0031 16.5 0.0 0.011 14.8 0.0 1.9 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EAU87543.2 - 0.0058 16.0 0.2 0.051 13.0 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EAU87543.2 - 0.055 13.4 0.0 0.055 13.4 0.0 3.3 2 1 0 2 2 1 0 AAA ATPase domain AAA_23 PF13476.1 EAU87543.2 - 0.11 12.8 0.2 0.11 12.8 0.1 3.5 2 1 0 2 2 1 0 AAA domain SMC_N PF02463.14 EAU87543.2 - 0.17 11.0 3.3 0.18 11.0 0.2 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Guanylate_kin PF00625.16 EAU87543.2 - 0.32 10.4 7.4 0.71 9.2 0.0 3.2 3 0 0 3 3 3 0 Guanylate kinase AAA_10 PF12846.2 EAU87543.2 - 0.51 9.7 0.0 0.51 9.7 0.0 2.5 2 1 0 2 2 1 0 AAA-like domain AAA_17 PF13207.1 EAU87543.2 - 0.61 10.9 2.2 4.3 8.1 0.0 3.0 4 0 0 4 4 3 0 AAA domain Seryl_tRNA_N PF02403.17 EAU87543.2 - 1.1 9.3 32.6 0.12 12.4 1.4 4.5 1 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 EAU87543.2 - 2.5 7.2 38.2 7.1 5.7 2.6 4.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EAU87543.2 - 4.9 6.9 43.6 11 5.7 4.1 3.9 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EAU87543.2 - 5.1 6.1 14.0 2.9 6.9 4.0 2.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AIG1 PF04548.11 EAU87544.1 - 6.5e-13 48.2 0.1 6.5e-13 48.2 0.0 2.1 3 0 0 3 3 3 1 AIG1 family MMR_HSR1 PF01926.18 EAU87544.1 - 7.6e-09 35.5 0.0 2.4e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAU87544.1 - 4e-06 26.1 0.1 1e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EAU87544.1 - 6.1e-05 22.3 0.1 0.00016 20.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 EAU87544.1 - 0.00033 20.9 5.1 0.0004 20.6 0.0 2.7 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 EAU87544.1 - 0.0038 17.0 10.5 0.015 15.0 0.1 3.7 4 1 1 5 5 4 2 Dynamin family GTP_EFTU PF00009.22 EAU87544.1 - 0.01 15.2 0.8 0.13 11.6 0.5 2.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAU87544.1 - 0.014 14.5 0.3 0.035 13.2 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAU87544.1 - 0.018 14.2 0.8 0.055 12.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EAU87544.1 - 0.019 15.4 1.2 0.18 12.3 0.0 2.9 2 2 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EAU87544.1 - 0.039 13.4 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2782 PF11191.3 EAU87544.1 - 0.069 13.1 0.1 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) AAA_16 PF13191.1 EAU87544.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.7 2 1 0 2 2 1 0 AAA ATPase domain IncA PF04156.9 EAU87544.1 - 0.13 11.8 30.9 0.019 14.5 8.1 2.5 1 1 1 2 2 2 0 IncA protein DUF713 PF05218.9 EAU87544.1 - 0.4 10.3 0.0 0.4 10.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF713) DUF4559 PF15112.1 EAU87544.1 - 0.62 9.1 12.8 0.24 10.5 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) BLOC1_2 PF10046.4 EAU87544.1 - 2.6 8.2 8.0 1.2 9.3 2.0 2.9 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 EAU87544.1 - 5.8 6.0 17.7 5.4 6.1 9.5 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 EAU87544.1 - 6.1 7.2 34.7 7 7.0 13.5 5.2 3 1 0 4 4 3 0 Protein of unknown function (DUF904) APG6 PF04111.7 EAU87544.1 - 7.9 5.4 25.1 0.42 9.6 9.0 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Acetyltransf_1 PF00583.19 EAU87547.2 - 1.7e-15 56.7 0.0 2.5e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAU87547.2 - 7.8e-08 31.9 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EAU87547.2 - 6.6e-07 29.4 0.0 9.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAU87547.2 - 7.6e-07 29.1 0.0 1.2e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAU87547.2 - 1.3e-06 28.4 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAU87547.2 - 2.5e-05 24.4 0.0 3.7e-05 23.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU87547.2 - 0.00039 20.2 0.0 0.00062 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU87547.2 - 0.036 14.0 0.0 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 EAU87548.1 - 8.6e-05 21.2 2.4 0.034 12.6 0.2 2.2 2 0 0 2 2 2 2 Amino acid permease HSP70 PF00012.15 EAU87549.2 - 1.8e-254 845.2 7.7 2.9e-254 844.5 5.4 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAU87549.2 - 2.1e-22 79.1 0.5 4.2e-21 74.8 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EAU87549.2 - 0.0006 18.7 0.6 0.032 13.0 0.3 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EAU87549.2 - 0.049 12.7 0.2 0.049 12.7 0.1 2.4 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Spectrin PF00435.16 EAU87549.2 - 0.16 12.2 7.9 1.7 8.9 0.1 3.5 3 0 0 3 3 3 0 Spectrin repeat Mrr_N PF14338.1 EAU87549.2 - 1.9 8.5 5.6 4 7.5 0.0 3.4 4 0 0 4 4 4 0 Mrr N-terminal domain Seryl_tRNA_N PF02403.17 EAU87549.2 - 2.8 7.9 9.5 13 5.8 0.1 3.4 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LUC7 PF03194.10 EAU87550.2 - 0.0093 15.5 0.9 0.014 14.9 0.6 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Dynamin_N PF00350.18 EAU87550.2 - 0.027 14.2 0.7 0.096 12.4 0.0 2.0 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 EAU87550.2 - 0.079 12.9 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Seryl_tRNA_N PF02403.17 EAU87550.2 - 0.4 10.7 5.8 0.74 9.8 4.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TauD PF02668.11 EAU87552.1 - 1.8e-56 191.6 0.2 2.2e-56 191.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Crust_neurohorm PF01147.12 EAU87554.1 - 0.023 13.9 0.1 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family VHS PF00790.14 EAU87566.2 - 1.2e-09 37.9 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EAU87566.2 - 6.3e-07 29.3 0.9 0.0018 18.2 0.0 2.3 2 0 0 2 2 2 2 GAT domain 4HBT PF03061.17 EAU87567.2 - 1.2e-05 25.3 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Tetraspannin PF00335.15 EAU87568.2 - 0.011 15.0 14.3 2.3 7.4 9.9 2.6 1 1 0 1 1 1 0 Tetraspanin family tRNA-synt_1 PF00133.17 EAU87569.1 - 3.4e-35 121.1 0.0 2.1e-17 62.3 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EAU87569.1 - 2.6e-16 59.2 0.0 4e-08 32.3 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EAU87569.1 - 9e-15 54.7 0.3 2.8e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EAU87569.1 - 4.7e-07 29.2 0.0 9.1e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain IL13 PF03487.8 EAU87569.1 - 0.055 13.1 0.6 17 5.2 0.0 3.3 3 0 0 3 3 3 0 Interleukin-13 HMG_box PF00505.14 EAU87573.2 - 7.4e-24 83.8 1.9 7.4e-24 83.8 1.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU87573.2 - 2.4e-19 69.4 1.6 2.4e-19 69.4 1.1 1.7 2 0 0 2 2 2 1 HMG-box domain YABBY PF04690.8 EAU87573.2 - 0.0012 19.1 0.7 0.0012 19.1 0.5 1.8 1 1 1 2 2 2 1 YABBY protein CHDNT PF08073.7 EAU87573.2 - 0.0017 18.0 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain Oxysterol_BP PF01237.13 EAU87574.2 - 1.3e-69 234.3 1.5 1.1e-68 231.3 1.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein SAB PF04382.8 EAU87580.2 - 0.013 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 SAB domain Corona_S1 PF01600.11 EAU87583.2 - 0.01 14.1 0.0 0.014 13.7 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S1 glycoprotein SnoaL_2 PF12680.2 EAU87594.2 - 4e-06 27.1 0.0 5.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EAU87594.2 - 0.0016 18.3 0.0 0.0037 17.1 0.0 1.5 1 1 1 2 2 2 1 SnoaL-like domain DUF1949 PF09186.6 EAU87594.2 - 0.023 14.3 0.1 38 3.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1949) TFIIS_C PF01096.13 EAU87595.2 - 3.4e-15 55.3 0.4 3.4e-15 55.3 0.3 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EAU87595.2 - 2.1e-09 36.8 0.4 2.1e-09 36.8 0.3 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EAU87595.2 - 9.3e-05 22.1 1.5 0.2 11.4 0.2 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 EAU87595.2 - 0.039 13.7 6.4 3 7.7 0.0 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IBR PF01485.16 EAU87595.2 - 0.048 13.5 2.7 1.5 8.7 0.4 2.2 2 0 0 2 2 2 0 IBR domain DUF2387 PF09526.5 EAU87595.2 - 0.059 13.2 5.6 0.59 10.0 0.6 2.1 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zinc-ribbons_6 PF07191.7 EAU87595.2 - 0.076 12.8 2.1 1 9.2 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbons zf-TFIIB PF13453.1 EAU87595.2 - 0.087 12.0 5.3 0.16 11.2 0.3 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-BED PF02892.10 EAU87595.2 - 0.13 12.0 4.4 2.5 7.9 0.0 2.6 2 1 1 3 3 3 0 BED zinc finger DZR PF12773.2 EAU87595.2 - 0.15 11.8 5.4 6.3 6.6 3.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon Rubredoxin PF00301.15 EAU87595.2 - 0.22 11.4 6.0 4.6 7.2 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin Zn-ribbon_8 PF09723.5 EAU87595.2 - 0.34 10.8 3.0 2.8 7.9 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Rep_fac-A_C PF08646.5 EAU87595.2 - 0.43 10.2 3.5 0.65 9.6 0.4 2.0 1 1 1 2 2 2 0 Replication factor-A C terminal domain zf-C4_Topoisom PF01396.14 EAU87595.2 - 1 8.9 4.3 16 5.1 0.2 2.5 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger C1_1 PF00130.17 EAU87595.2 - 1.7 8.4 6.0 0.54 10.0 0.5 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Opy2 PF09463.5 EAU87595.2 - 2 8.5 9.1 1.9 8.6 0.1 3.0 2 1 0 2 2 2 0 Opy2 protein zf-H2C2_2 PF13465.1 EAU87595.2 - 2.3 8.6 6.3 10 6.6 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_3 PF14369.1 EAU87595.2 - 4 7.5 6.4 11 6.1 0.1 2.7 2 1 0 2 2 2 0 zinc-finger zf-C3HC4_4 PF15227.1 EAU87595.2 - 4.9 7.1 7.7 5.7 6.9 0.2 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Pyridoxal_deC PF00282.14 EAU87596.2 - 6e-19 67.7 0.0 2.4e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EAU87596.2 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SPRY PF00622.23 EAU87597.1 - 7.6e-11 42.1 0.0 1.3e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain BTB PF00651.26 EAU87598.2 - 8.8e-10 38.5 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Apc1 PF12859.2 EAU87599.1 - 1.7e-13 50.6 0.1 7.1e-13 48.6 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EAU87599.1 - 0.0016 18.5 6.8 4.5 7.7 0.1 5.4 5 0 0 5 5 5 2 Proteasome/cyclosome repeat BAG PF02179.11 EAU87601.2 - 3.2e-07 30.3 2.1 4.1e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 BAG domain Herpes_capsid PF06112.6 EAU87602.1 - 1.4 8.9 8.2 1.8 8.5 5.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Polyketide_cyc2 PF10604.4 EAU87604.2 - 2.3e-07 31.0 0.1 4.3e-07 30.1 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EAU87604.2 - 0.019 14.9 0.1 0.041 13.8 0.0 1.6 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 EAU87604.2 - 0.037 14.1 0.1 8.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EAU87605.1 - 2.1e-11 44.1 0.7 4.5e-11 43.0 0.5 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EAU87605.1 - 3.1e-05 23.9 0.1 4.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 EAU87605.1 - 0.062 13.4 0.1 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein p450 PF00067.17 EAU87606.2 - 2.2e-68 230.8 0.0 2.7e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CTP_transf_2 PF01467.21 EAU87607.2 - 4.5e-18 65.7 0.0 6.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Sirohm_synth_M PF14824.1 EAU87607.2 - 9.9 5.2 7.8 1 8.4 0.8 2.3 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DSPc PF00782.15 EAU87608.2 - 1.2e-20 73.4 0.0 4.2e-20 71.6 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EAU87608.2 - 3e-06 27.5 0.0 1.6e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 EAU87608.2 - 0.18 11.1 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PIH1 PF08190.7 EAU87609.2 - 1.8e-14 53.9 7.3 8.8e-14 51.6 0.1 3.5 1 1 0 2 2 2 1 pre-RNA processing PIH1/Nop17 DAHP_synth_1 PF00793.15 EAU87610.2 - 6.1e-93 310.4 0.0 7.2e-93 310.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AAA_12 PF13087.1 EAU87611.2 - 8.4e-40 136.2 0.0 1.5e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU87611.2 - 1.3e-27 96.9 0.2 3.4e-15 56.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EAU87611.2 - 2.3e-10 40.0 0.0 1.1e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAU87611.2 - 1.3e-07 31.4 0.0 2.3e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EAU87611.2 - 0.00018 21.1 1.3 1.1 8.7 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EAU87611.2 - 0.00022 20.6 0.0 0.0012 18.2 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EAU87611.2 - 0.006 16.0 0.0 0.049 13.0 0.0 2.0 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 EAU87611.2 - 0.017 14.7 0.0 0.17 11.4 0.0 2.6 3 0 0 3 3 3 0 Helicase UvrD_C_2 PF13538.1 EAU87611.2 - 0.019 15.1 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EAU87611.2 - 0.052 12.4 0.0 7.7 5.3 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ResIII PF04851.10 EAU87611.2 - 0.079 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EAU87611.2 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EAU87611.2 - 1 10.2 5.5 15 6.4 0.1 3.2 4 0 0 4 4 3 0 AAA domain DUF1365 PF07103.6 EAU87613.2 - 1.4e-27 96.3 0.0 2.7e-27 95.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) AAA_12 PF13087.1 EAU87614.2 - 2.2e-57 193.6 0.0 4.7e-57 192.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU87614.2 - 6.6e-28 97.8 3.6 3.6e-23 82.3 0.5 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EAU87614.2 - 2.2e-12 46.5 0.3 3e-11 42.9 0.2 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAU87614.2 - 3.1e-08 33.4 0.4 1.1e-06 28.4 0.3 2.3 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EAU87614.2 - 1e-05 25.0 0.4 4e-05 23.0 0.3 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EAU87614.2 - 0.002 17.6 0.0 3 7.2 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DOR PF14839.1 EAU87614.2 - 0.7 9.6 3.2 1.3 8.7 2.2 1.3 1 0 0 1 1 1 0 DOR family zf-RanBP PF00641.13 EAU87615.1 - 1.6e-05 23.9 15.8 0.00038 19.4 1.5 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others LIM PF00412.17 EAU87616.1 - 9.4e-23 80.0 24.1 8.5e-12 44.9 4.8 2.2 2 0 0 2 2 2 2 LIM domain Hamartin PF04388.7 EAU87616.1 - 0.088 11.4 3.5 0.14 10.7 2.4 1.3 1 0 0 1 1 1 0 Hamartin protein UPF0547 PF10571.4 EAU87616.1 - 0.22 11.2 6.1 5.9 6.6 0.5 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-DNA_Pol PF08996.5 EAU87616.1 - 0.51 9.6 8.9 1.4 8.2 0.9 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger eIF-5a PF01287.15 EAU87617.1 - 7.5e-28 96.2 0.2 1.1e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EAU87617.1 - 2.4e-05 23.8 0.8 5.8e-05 22.6 0.6 1.7 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EAU87617.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Bromo_TP PF07524.8 EAU87618.2 - 1.3e-07 31.2 0.2 2.2e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EAU87618.2 - 0.095 12.8 0.3 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF159 PF02586.9 EAU87619.2 - 4.9e-50 169.9 0.1 8e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 DLIC PF05783.6 EAU87619.2 - 0.0061 15.2 0.6 0.0061 15.2 0.4 1.7 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) RNase_H2-Ydr279 PF09468.5 EAU87619.2 - 1.4 8.0 10.2 2.5 7.2 7.0 1.4 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) IMPDH PF00478.20 EAU87620.1 - 8.4e-135 449.1 0.0 2.5e-134 447.6 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EAU87620.1 - 8.4e-18 63.8 0.3 1.8e-07 30.7 0.1 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EAU87620.1 - 4.1e-10 39.0 1.4 9.6e-10 37.8 0.8 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EAU87620.1 - 7.9e-10 38.3 5.2 5.7e-07 29.0 2.5 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.9 EAU87620.1 - 0.00011 21.4 0.7 0.00023 20.3 0.5 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EAU87620.1 - 0.0005 19.3 3.0 0.00084 18.6 0.6 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein Dus PF01207.12 EAU87620.1 - 0.15 10.8 1.0 0.72 8.6 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF1273 PF06908.6 EAU87620.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DUF2263 PF10021.4 EAU87621.1 - 7.6e-29 100.6 0.0 1.2e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) PARP PF00644.15 EAU87623.2 - 2.7e-09 36.7 0.2 1.1e-08 34.7 0.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 EAU87624.2 - 7.1e-08 32.1 2.6 5.4e-07 29.2 0.4 3.0 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 EAU87625.2 - 8.9e-08 31.7 1.2 0.0001 21.8 0.3 2.8 2 1 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Syja_N PF02383.13 EAU87629.2 - 4.8e-86 288.4 0.0 6.9e-86 287.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain PAN_4 PF14295.1 EAU87630.1 - 0.029 14.0 1.1 0.045 13.4 0.3 1.7 1 1 0 1 1 1 0 PAN domain NUC194 PF08163.7 EAU87630.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 NUC194 domain RRM_1 PF00076.17 EAU87631.2 - 2.6e-28 97.4 0.4 1.3e-15 56.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU87631.2 - 2.7e-22 78.5 0.1 1.1e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU87631.2 - 1.3e-10 40.9 0.1 1.1e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EAU87631.2 - 0.0087 15.5 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Pkinase PF00069.20 EAU87632.1 - 4.8e-51 173.3 0.0 7.6e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87632.1 - 1e-46 159.1 0.0 1.4e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EAU87632.1 - 2.6e-07 30.2 1.0 5.5e-07 29.2 0.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 EAU87632.1 - 0.0041 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU87632.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EAU87632.1 - 0.022 13.8 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.24 EAU87632.1 - 0.057 13.1 3.6 0.13 12.0 2.5 1.6 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 EAU87632.1 - 0.074 13.0 1.1 0.17 11.9 0.8 1.7 1 0 0 1 1 1 0 C1-like domain C1_2 PF03107.11 EAU87632.1 - 0.091 12.8 2.5 0.17 12.0 1.7 1.5 1 0 0 1 1 1 0 C1 domain TFIIF_alpha PF05793.7 EAU87632.1 - 0.83 7.9 2.7 1.2 7.4 1.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Actino_peptide PF14408.1 EAU87633.2 - 4 7.4 11.9 11 6.0 0.3 4.0 3 0 0 3 3 3 0 Ribosomally synthesized peptide in actinomycetes SUR7 PF06687.7 EAU87640.1 - 4.2e-14 52.6 11.6 9.2e-14 51.5 8.1 1.5 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EAU87640.1 - 1.8e-05 24.5 4.7 1.8e-05 24.5 3.2 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 EAU87640.1 - 0.0049 16.8 2.4 0.009 16.0 1.6 1.5 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF4381 PF14316.1 EAU87640.1 - 0.022 14.8 0.5 0.059 13.4 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Ish1 PF10281.4 EAU87641.2 - 3.1e-41 139.0 38.0 2.3e-07 30.7 0.5 8.2 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EAU87641.2 - 1.3e-05 24.5 0.2 3.1 7.4 0.0 5.0 4 0 0 4 4 4 2 HeH/LEM domain Vicilin_N PF04702.7 EAU87641.2 - 0.083 12.5 4.5 0.16 11.5 3.1 1.4 1 0 0 1 1 1 0 Vicilin N terminal region DUF883 PF05957.8 EAU87641.2 - 6.3 7.2 28.4 8.3 6.8 4.1 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.20 EAU87642.1 - 3.6e-05 23.0 0.0 0.00042 19.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87642.1 - 0.00031 19.8 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LSM PF01423.17 EAU87644.2 - 3e-18 65.1 0.1 3.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT PF02985.17 EAU87645.1 - 5.1e-21 72.8 10.6 0.00016 21.5 0.0 11.0 13 0 0 13 13 13 5 HEAT repeat HEAT_EZ PF13513.1 EAU87645.1 - 8.8e-19 67.4 6.8 8.7e-09 35.6 0.0 8.9 9 1 1 10 10 10 2 HEAT-like repeat HEAT_2 PF13646.1 EAU87645.1 - 4.1e-17 62.2 10.6 4.1e-06 26.9 0.0 8.1 3 1 3 7 7 7 5 HEAT repeats IBN_N PF03810.14 EAU87645.1 - 2.4e-12 46.5 0.8 8.5e-11 41.6 0.2 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 EAU87645.1 - 1.1e-08 34.5 5.3 0.0027 17.4 0.0 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 EAU87645.1 - 0.00031 20.6 0.1 0.11 12.3 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) MMS19_N PF14500.1 EAU87645.1 - 0.0054 16.0 0.1 0.65 9.2 0.1 3.2 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.7 EAU87645.1 - 0.054 13.1 1.6 1.1e+02 2.4 0.1 5.1 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis p450 PF00067.17 EAU87646.2 - 1.8e-60 204.8 0.0 2.3e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.15 EAU87647.1 - 1.3e-73 247.9 15.4 5.2e-73 245.9 2.8 2.7 2 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EAU87647.1 - 1.8e-05 23.5 0.1 3.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein SR-25 PF10500.4 EAU87647.1 - 0.00074 19.0 6.2 0.00074 19.0 4.3 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1869 PF08956.5 EAU87647.1 - 0.068 12.7 0.1 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) RAP-1 PF03085.10 EAU87647.1 - 0.072 12.4 0.0 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Membr_traf_MHD PF10540.4 EAU87648.2 - 9e-19 67.6 1.1 2.2e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EAU87648.2 - 1.1e-08 34.7 0.0 3.7e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 C2 domain CitG PF01874.11 EAU87648.2 - 0.0073 15.5 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 ATP:dephospho-CoA triphosphoribosyl transferase Neurensin PF14927.1 EAU87649.2 - 0.018 14.4 0.1 0.4 10.0 0.1 2.2 2 0 0 2 2 2 0 Neurensin zf-C2H2 PF00096.21 EAU87650.2 - 1.6e-34 116.1 58.1 0.00012 22.2 0.6 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU87650.2 - 4.2e-29 99.3 52.3 6.1e-07 29.4 0.7 10.5 12 0 0 12 12 12 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU87650.2 - 7.4e-17 60.3 56.4 0.00042 20.4 0.6 9.3 9 0 0 9 9 9 7 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EAU87650.2 - 3.9e-08 33.0 18.5 0.44 10.8 0.2 7.7 7 0 0 7 7 7 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EAU87650.2 - 5.9e-07 29.4 6.6 0.85 9.8 0.1 6.7 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAU87650.2 - 1.3e-06 28.1 9.2 0.0018 18.0 0.2 5.8 5 1 0 5 5 5 1 C2H2-type zinc finger zf-TRAF PF02176.13 EAU87650.2 - 2.8e-05 24.3 12.2 0.18 12.2 1.0 3.8 3 0 0 3 3 3 3 TRAF-type zinc finger zf-met PF12874.2 EAU87650.2 - 0.0024 18.0 17.9 7.4 6.9 0.4 7.6 9 0 0 9 9 8 2 Zinc-finger of C2H2 type Terminase_6 PF03237.10 EAU87650.2 - 0.049 12.3 0.0 5.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Terminase-like family zf-LYAR PF08790.6 EAU87650.2 - 0.18 11.5 11.5 19 5.0 0.0 4.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger GAGA PF09237.6 EAU87650.2 - 0.23 11.1 12.1 2.6 7.7 0.5 5.3 5 0 0 5 5 5 0 GAGA factor Reo_sigmaC PF04582.7 EAU87651.2 - 1.6e-09 37.3 28.7 0.0089 15.2 1.1 4.9 2 2 2 4 4 4 4 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EAU87651.2 - 1.5e-07 29.6 56.4 1.5e-07 29.6 39.1 3.1 1 1 1 3 3 3 1 Myosin tail Tropomyosin_1 PF12718.2 EAU87651.2 - 2.7e-07 30.5 21.4 2.7e-07 30.5 14.9 5.7 1 1 5 6 6 5 1 Tropomyosin like CENP-Q PF13094.1 EAU87651.2 - 0.00087 19.3 18.4 0.00087 19.3 12.8 6.8 1 1 5 6 6 6 3 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.1 EAU87651.2 - 0.0011 18.4 20.3 0.0011 18.4 14.1 5.2 3 2 2 5 5 4 1 Domain of unknown function (DUF4201) TMF_DNA_bd PF12329.3 EAU87651.2 - 0.0034 17.1 4.8 0.0034 17.1 3.4 9.1 4 2 5 9 9 9 5 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EAU87651.2 - 0.0062 16.3 19.7 0.0062 16.3 13.7 6.0 1 1 5 6 6 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF904 PF06005.7 EAU87651.2 - 0.01 16.0 0.5 0.01 16.0 0.4 8.4 4 1 2 6 6 4 0 Protein of unknown function (DUF904) DUF869 PF05911.6 EAU87651.2 - 0.018 13.3 80.3 0.015 13.5 33.5 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) IncA PF04156.9 EAU87651.2 - 0.77 9.3 109.8 6.3 6.3 8.1 5.6 1 1 4 5 5 5 0 IncA protein ADIP PF11559.3 EAU87651.2 - 6.6 6.6 89.2 2.5 7.9 4.1 7.1 2 2 5 7 7 7 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EAU87651.2 - 7.6 5.6 88.2 0.1 11.7 17.9 4.5 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding AA_permease_2 PF13520.1 EAU87652.2 - 4.4e-60 203.4 44.5 5.5e-60 203.0 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAU87652.2 - 8.8e-17 60.5 38.8 1.5e-16 59.8 26.9 1.3 1 1 0 1 1 1 1 Amino acid permease Ldh_1_N PF00056.18 EAU87654.2 - 8e-47 158.6 0.3 1.3e-46 157.8 0.1 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EAU87654.2 - 1.2e-37 129.3 0.0 1.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EAU87654.2 - 0.0027 16.4 0.0 0.0037 16.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EAU87654.2 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Gp_dh_C PF02800.15 EAU87655.2 - 4e-73 244.0 0.0 6.3e-73 243.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EAU87655.2 - 1.3e-60 203.6 0.2 2.5e-60 202.8 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EAU87655.2 - 0.0042 16.9 0.3 0.012 15.4 0.2 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EAU87655.2 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 EAU87656.1 - 7.2e-70 233.4 0.0 1e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EAU87656.1 - 5.2e-38 130.3 0.2 9.3e-38 129.5 0.2 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain BP28CT PF08146.7 EAU87657.2 - 8e-25 87.3 0.6 8.3e-24 84.0 0.0 3.1 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EAU87657.2 - 2.1e-18 66.4 1.2 2.1e-18 66.4 0.8 4.7 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 zf-RING_3 PF14369.1 EAU87660.2 - 1.1 9.3 4.1 0.56 10.2 0.5 2.2 3 0 0 3 3 3 0 zinc-finger RNA_pol_I_A49 PF06870.7 EAU87662.1 - 6.7e-88 294.8 1.9 7.8e-88 294.6 1.3 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SET PF00856.23 EAU87663.2 - 1.1e-21 77.8 0.1 1.1e-21 77.8 0.1 4.1 3 2 0 3 3 3 1 SET domain SRI PF08236.6 EAU87663.2 - 6.1e-16 58.1 9.5 6.1e-16 58.1 6.6 3.0 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain CHAT PF12770.2 EAU87665.2 - 2.5e-26 92.4 0.0 6.5e-26 91.1 0.0 1.7 1 1 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EAU87665.2 - 0.011 15.3 8.0 0.51 10.0 0.5 3.7 3 1 0 3 3 3 0 TPR repeat zf-CCHC PF00098.18 EAU87670.2 - 0.64 10.0 4.0 0.22 11.4 0.9 1.7 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 EAU87670.2 - 0.69 9.8 3.3 0.33 10.8 0.2 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Cauli_VI PF01693.11 EAU87678.1 - 0.00036 20.4 0.0 0.00082 19.3 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3295 PF11702.3 EAU87680.2 - 0.049 12.6 0.1 0.073 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) COesterase PF00135.23 EAU87681.1 - 2.6e-85 287.1 0.0 6.4e-78 262.7 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU87681.1 - 7.4e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU87681.1 - 0.00046 19.9 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU87681.1 - 0.0031 17.4 0.0 0.0072 16.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EAU87681.1 - 0.0064 15.7 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 EAU87681.1 - 0.041 13.2 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EAU87681.1 - 0.042 13.0 0.2 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF348 PF03990.9 EAU87681.1 - 0.11 12.1 0.1 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF348) UQ_con PF00179.21 EAU87683.2 - 4.3e-17 61.8 0.0 6.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PEMT PF04191.8 EAU87684.1 - 2.2e-30 104.9 2.8 2.2e-30 104.9 1.9 1.7 3 0 0 3 3 3 1 Phospholipid methyltransferase Glyco_hydro_3 PF00933.16 EAU87685.2 - 3.7e-75 252.6 0.0 5.7e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAU87685.2 - 6.3e-56 189.4 0.0 1.3e-55 188.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAU87685.2 - 2e-16 59.6 0.0 3.8e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 EAU87688.2 - 3e-78 262.8 0.0 4e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAU87688.2 - 2.5e-53 180.9 0.0 7.9e-53 179.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAU87688.2 - 4.3e-19 68.2 0.0 8.5e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Omptin PF01278.15 EAU87688.2 - 0.094 11.7 0.1 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Omptin family SKN1 PF03935.10 EAU87689.2 - 7e-175 581.9 7.7 8.2e-174 578.4 5.3 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 EAU87690.2 - 3.6e-172 573.0 3.0 4.4e-172 572.7 2.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GMC_oxred_N PF00732.14 EAU87691.1 - 2.7e-60 204.0 0.0 3.4e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87691.1 - 2.6e-35 121.8 0.0 4.4e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU87691.1 - 1.9e-05 24.5 0.1 0.0001 22.2 0.1 2.4 2 1 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU87691.1 - 2.3e-05 23.4 0.4 0.00048 19.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAU87691.1 - 3e-05 23.0 0.1 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EAU87691.1 - 0.0014 18.7 0.1 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAU87691.1 - 0.0017 17.3 0.1 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DUF723 PF05265.8 EAU87691.1 - 0.0018 18.0 0.0 0.0048 16.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF723) Thi4 PF01946.12 EAU87691.1 - 0.0026 16.8 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EAU87691.1 - 0.0068 16.3 0.1 0.053 13.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU87691.1 - 0.047 12.1 0.1 0.088 11.2 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.1 EAU87691.1 - 0.066 12.1 0.1 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UCR_TM PF02921.9 EAU87691.1 - 0.074 13.2 0.1 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Rtt106 PF08512.7 EAU87692.1 - 1.2e-26 92.4 0.0 2.2e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like TrkH PF02386.11 EAU87693.2 - 4.1e-57 193.3 0.5 4.1e-50 170.3 0.0 3.0 2 1 0 2 2 2 2 Cation transport protein DUF2306 PF10067.4 EAU87693.2 - 3.2 7.9 7.5 0.4 10.8 1.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) Mito_carr PF00153.22 EAU87694.2 - 2.7e-70 232.1 5.4 9.4e-23 79.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EAU87694.2 - 0.16 12.0 3.7 4.1 7.4 0.0 3.7 3 2 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family HEM4 PF02602.10 EAU87695.1 - 8.5e-32 110.2 0.0 1e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Integrase_1 PF12835.2 EAU87695.1 - 0.099 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Integrase L27_2 PF09045.5 EAU87696.1 - 0.037 13.5 0.3 0.058 12.9 0.2 1.3 1 0 0 1 1 1 0 L27_2 MIS13 PF08202.6 EAU87696.1 - 0.052 12.5 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Lyase_1 PF00206.15 EAU87697.1 - 4.9e-23 81.7 0.0 7e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EAU87697.1 - 5.7e-17 61.4 0.0 1.6e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF4089 PF13318.1 EAU87697.1 - 0.032 14.5 0.1 0.12 12.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Histone PF00125.19 EAU87700.2 - 4.2e-20 71.6 0.0 6.1e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAU87700.2 - 0.0047 16.9 0.0 0.0063 16.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-H2C2 PF09337.5 EAU87701.2 - 0.0042 16.4 0.5 0.0084 15.4 0.3 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Pkinase PF00069.20 EAU87704.2 - 1.6e-69 233.9 0.0 2.2e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87704.2 - 9.7e-38 129.7 0.0 1.5e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU87704.2 - 1.6e-05 24.0 0.0 2.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EAU87704.2 - 0.0048 16.2 0.2 0.0091 15.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EAU87704.2 - 0.044 13.5 0.1 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.17 EAU87705.2 - 5.1e-53 180.2 0.0 1.1e-52 179.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 SNase PF00565.12 EAU87708.2 - 1.2e-19 70.5 0.0 1.7e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Baculo_PEP_C PF04513.7 EAU87709.1 - 0.0034 17.2 1.0 0.0042 16.8 0.7 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tcp11 PF05794.8 EAU87709.1 - 0.0064 15.2 0.5 0.007 15.1 0.3 1.0 1 0 0 1 1 1 1 T-complex protein 11 UPF0118 PF01594.11 EAU87709.1 - 0.0073 15.3 1.5 0.01 14.8 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF20 Syntaxin PF00804.20 EAU87709.1 - 0.0091 16.1 0.4 0.012 15.7 0.3 1.1 1 0 0 1 1 1 1 Syntaxin DUF2076 PF09849.4 EAU87709.1 - 0.037 14.0 3.1 0.043 13.8 2.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Sec10 PF07393.6 EAU87709.1 - 0.067 11.3 0.7 0.077 11.1 0.5 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF883 PF05957.8 EAU87709.1 - 0.59 10.5 5.9 4.9 7.6 4.0 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Bunya_RdRp PF04196.7 EAU87709.1 - 1.9 6.3 4.3 2.3 6.1 3.0 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase DUF4523 PF15023.1 EAU87709.1 - 2.2 7.7 4.5 2.8 7.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF725 PF05267.7 EAU87709.1 - 2.4 8.0 7.7 3.1 7.7 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Late_protein_L2 PF00513.13 EAU87709.1 - 6.4 5.5 8.6 7.2 5.3 5.9 1.0 1 0 0 1 1 1 0 Late Protein L2 zf-C2H2 PF00096.21 EAU87710.2 - 0.023 14.9 3.5 3.4 8.1 0.2 2.8 2 1 0 2 2 2 0 Zinc finger, C2H2 type UPF0547 PF10571.4 EAU87710.2 - 0.055 13.1 0.1 0.13 11.9 0.1 1.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 c-SKI_SMAD_bind PF08782.5 EAU87710.2 - 0.074 13.1 0.3 0.54 10.4 0.3 1.8 1 1 1 2 2 2 0 c-SKI Smad4 binding domain zf-TFIIB PF13453.1 EAU87710.2 - 0.29 10.3 1.6 0.63 9.2 1.1 1.6 1 1 0 1 1 1 0 Transcription factor zinc-finger SWIB PF02201.13 EAU87711.1 - 7.9e-17 60.7 0.0 2.4e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain CENP-F_leu_zip PF10473.4 EAU87711.1 - 0.042 13.7 0.7 0.084 12.7 0.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ras PF00071.17 EAU87712.2 - 7.9e-46 155.3 0.3 2e-45 154.1 0.2 1.7 1 0 0 1 1 1 1 Ras family BAR PF03114.13 EAU87712.2 - 3.6e-32 111.7 9.1 5e-32 111.2 6.3 1.2 1 0 0 1 1 1 1 BAR domain Miro PF08477.8 EAU87712.2 - 6.4e-15 55.6 0.5 1.9e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein SH3_1 PF00018.23 EAU87712.2 - 6.4e-10 38.2 0.1 1.3e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU87712.2 - 1.5e-09 37.2 0.0 2.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU87712.2 - 5.5e-08 32.1 0.1 1.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arf PF00025.16 EAU87712.2 - 7.3e-08 31.8 0.0 1.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU87712.2 - 4.3e-05 23.0 3.1 8.2e-05 22.1 0.2 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAU87712.2 - 0.00017 21.4 0.3 0.00067 19.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EAU87712.2 - 0.0015 18.3 1.6 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EAU87712.2 - 0.0017 18.0 4.8 0.013 15.2 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase OmpH PF03938.9 EAU87712.2 - 0.0085 16.0 9.6 0.0085 16.0 6.7 2.1 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF258 PF03193.11 EAU87712.2 - 0.034 13.3 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EAU87712.2 - 0.071 12.3 0.0 0.69 9.1 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Sec34 PF04136.10 EAU87712.2 - 0.16 11.6 3.6 0.33 10.6 2.5 1.5 1 0 0 1 1 1 0 Sec34-like family Dynamin_N PF00350.18 EAU87712.2 - 0.46 10.2 0.0 0.46 10.2 0.0 3.0 4 0 0 4 4 3 0 Dynamin family DUF342 PF03961.8 EAU87712.2 - 0.65 8.3 5.9 1.3 7.3 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EAU87712.2 - 3.9 5.1 7.1 5.7 4.6 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OEP PF02321.13 EAU87712.2 - 6.3 6.3 9.8 12 5.4 6.8 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein RR_TM4-6 PF06459.7 EAU87712.2 - 8.2 6.2 14.7 0.22 11.3 2.0 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 P16-Arc PF04699.9 EAU87713.1 - 5.5e-50 169.3 0.0 6.2e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2711 PF10924.3 EAU87713.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) p450 PF00067.17 EAU87714.2 - 2.1e-44 151.8 0.0 9.4e-29 100.2 0.1 2.9 2 1 0 2 2 2 2 Cytochrome P450 Ycf9 PF01737.12 EAU87714.2 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 YCF9 WD40 PF00400.27 EAU87715.2 - 4.9e-05 23.0 4.1 0.24 11.3 0.2 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Ndc1_Nup PF09531.5 EAU87718.2 - 0.87 7.9 4.6 1.2 7.4 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.4 EAU87718.2 - 8.3 4.9 11.7 13 4.3 8.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PseudoU_synth_2 PF00849.17 EAU87719.2 - 4e-29 101.5 0.0 5.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF4347 PF14252.1 EAU87719.2 - 0.15 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) SNF2_N PF00176.18 EAU87720.1 - 5.7e-66 222.3 0.1 7.5e-66 221.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU87720.1 - 1.8e-12 46.9 0.0 4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EAU87720.1 - 3.4e-06 26.6 3.9 2.1e-05 24.0 2.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EAU87720.1 - 3.9e-06 26.8 0.0 1.2e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EAU87720.1 - 9.3e-06 25.3 1.7 2.2e-05 24.1 1.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAU87720.1 - 5.2e-05 22.8 2.3 0.00013 21.6 1.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAU87720.1 - 0.0027 17.3 3.5 0.0091 15.6 2.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU87720.1 - 0.0055 16.6 5.2 0.022 14.7 3.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EAU87720.1 - 0.026 14.3 1.5 0.32 10.8 0.1 2.4 2 0 0 2 2 2 0 IBR domain Ada_Zn_binding PF02805.11 EAU87720.1 - 0.074 12.6 0.8 0.17 11.5 0.6 1.6 1 0 0 1 1 1 0 Metal binding domain of Ada zf-C3HC4_4 PF15227.1 EAU87720.1 - 0.1 12.5 5.2 0.027 14.3 1.1 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EAU87720.1 - 6.2 6.4 8.6 0.32 10.5 0.6 2.8 4 0 0 4 4 4 0 MIZ/SP-RING zinc finger DUF2613 PF11021.3 EAU87722.1 - 0.21 11.3 2.6 0.5 10.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF4366 PF14283.1 EAU87723.1 - 0.071 12.5 2.8 0.059 12.7 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) FAP PF07174.6 EAU87723.1 - 0.2 10.9 7.0 0.23 10.6 4.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) PT PF04886.7 EAU87723.1 - 0.24 10.7 9.2 6.7 6.1 6.4 3.1 1 1 0 1 1 1 0 PT repeat Neisseria_TspB PF05616.8 EAU87723.1 - 0.68 8.2 2.6 0.75 8.0 1.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SKN1 PF03935.10 EAU87725.2 - 4e-177 589.3 0.1 4.7e-177 589.1 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.10 EAU87726.2 - 2.5e-180 599.9 0.0 2.9e-180 599.7 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EAU87726.2 - 9.8e-05 21.7 0.1 0.00078 18.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RrnaAD PF00398.15 EAU87730.2 - 9.5e-56 188.7 0.1 2.3e-54 184.1 0.0 1.9 1 1 1 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EAU87730.2 - 1.3e-08 34.9 0.0 3.1e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU87730.2 - 3.6e-05 24.2 0.0 7.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU87730.2 - 4.1e-05 23.0 0.0 6.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EAU87730.2 - 7.8e-05 21.9 0.0 0.00018 20.7 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase PCMT PF01135.14 EAU87730.2 - 0.00014 21.4 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EAU87730.2 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAU87730.2 - 0.00097 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EAU87730.2 - 0.0014 18.2 0.0 0.0039 16.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU87730.2 - 0.0047 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU87730.2 - 0.0088 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU87730.2 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EAU87730.2 - 0.074 11.9 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.6 EAU87730.2 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) ATP-synt_ab PF00006.20 EAU87732.2 - 0.015 14.8 0.1 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SUR7 PF06687.7 EAU87733.1 - 3.1e-08 33.4 3.4 1e-07 31.7 2.3 1.8 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EAU87733.1 - 0.00093 18.9 0.3 0.0016 18.1 0.1 1.6 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction TctB PF07331.6 EAU87733.1 - 0.087 12.4 0.1 0.087 12.4 0.1 2.8 2 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF4231 PF14015.1 EAU87733.1 - 1 9.3 6.3 1.3 9.0 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) PrsW-protease PF13367.1 EAU87733.1 - 4.7 6.3 9.0 0.14 11.2 1.9 1.8 2 1 0 2 2 2 0 Protease prsW family Pkinase PF00069.20 EAU87734.2 - 4.9e-05 22.6 0.0 5.3e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Spo7_2_N PF15407.1 EAU87734.2 - 0.016 14.6 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 AAA_17 PF13207.1 EAU87738.2 - 9.9e-13 48.9 0.0 1.2e-12 48.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU87738.2 - 6e-05 23.3 0.0 9.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU87738.2 - 0.00021 21.2 0.0 0.00033 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU87738.2 - 0.00024 21.2 0.0 0.00065 19.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EAU87738.2 - 0.00076 19.3 0.0 0.0037 17.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase AAA_16 PF13191.1 EAU87738.2 - 0.0031 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 EAU87738.2 - 0.0031 16.2 0.0 0.0044 15.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 EAU87738.2 - 0.0037 16.7 0.0 0.0067 15.9 0.0 1.4 1 1 0 1 1 1 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EAU87738.2 - 0.0038 16.4 0.0 0.0053 15.9 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 EAU87738.2 - 0.0038 17.0 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EAU87738.2 - 0.0042 16.8 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EAU87738.2 - 0.0064 15.9 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EAU87738.2 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 EAU87738.2 - 0.017 14.6 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EAU87738.2 - 0.021 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter SUKH-4 PF14435.1 EAU87738.2 - 0.031 14.0 0.0 0.074 12.7 0.0 1.5 2 0 0 2 2 2 0 SUKH-4 immunity protein AAA_10 PF12846.2 EAU87738.2 - 0.037 13.4 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 EAU87738.2 - 0.038 13.6 0.0 0.075 12.6 0.0 1.5 1 1 0 1 1 1 0 NACHT domain MobB PF03205.9 EAU87738.2 - 0.064 12.9 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EAU87738.2 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAU87738.2 - 0.087 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EAU87738.2 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.1 EAU87738.2 - 0.098 12.6 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EAU87738.2 - 0.11 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain OTT_1508_deam PF14441.1 EAU87739.1 - 4.1e-09 36.3 0.0 9.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase PseudoU_synth_1 PF01416.15 EAU87740.1 - 9.9e-26 90.2 0.0 2.1e-15 57.0 0.0 3.3 2 2 0 2 2 2 2 tRNA pseudouridine synthase Lon_C PF05362.8 EAU87743.2 - 6.9e-60 201.8 2.4 6.4e-59 198.7 1.7 2.1 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EAU87743.2 - 3.8e-22 78.9 0.0 9.3e-22 77.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAU87743.2 - 1.4e-09 37.7 0.0 4e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON PF02190.11 EAU87743.2 - 1.8e-08 34.3 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EAU87743.2 - 9e-06 25.2 0.8 2.6e-05 23.7 0.0 2.1 3 0 0 3 3 3 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EAU87743.2 - 1.4e-05 25.1 2.9 0.0002 21.4 0.0 3.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EAU87743.2 - 0.00012 22.8 0.1 0.00059 20.6 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EAU87743.2 - 0.00085 19.2 0.0 0.003 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EAU87743.2 - 0.00089 19.1 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAU87743.2 - 0.00098 18.2 0.1 0.027 13.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAU87743.2 - 0.0026 17.9 3.3 0.06 13.4 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EAU87743.2 - 0.0065 15.8 0.0 0.023 14.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU87743.2 - 0.0066 16.7 0.4 0.065 13.5 0.0 2.6 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 EAU87743.2 - 0.0093 14.7 0.0 0.033 12.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_3 PF07726.6 EAU87743.2 - 0.011 15.3 0.0 0.097 12.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EAU87743.2 - 0.052 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAU87743.2 - 0.067 12.9 0.6 0.28 10.9 0.1 2.3 2 0 0 2 2 1 0 Part of AAA domain SKI PF01202.17 EAU87743.2 - 0.1 12.4 1.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 EAU87743.2 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EAU87743.2 - 0.14 12.3 0.0 0.7 10.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 EAU87743.2 - 0.19 11.2 0.0 0.47 9.9 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF607 PF04678.8 EAU87743.2 - 0.23 11.3 2.6 0.15 12.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF607 AAA_23 PF13476.1 EAU87743.2 - 0.4 10.9 4.6 6.2 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain F-box-like PF12937.2 EAU87745.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like Adaptin_N PF01602.15 EAU87746.1 - 2.9e-151 504.3 9.7 3.6e-151 504.0 6.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EAU87746.1 - 2.8e-28 98.9 4.9 5.6e-26 91.4 0.3 3.5 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EAU87746.1 - 5.9e-19 68.1 2.7 1.8e-08 34.5 0.0 5.3 2 1 2 4 4 4 4 HEAT repeats HEAT PF02985.17 EAU87746.1 - 3.8e-08 32.7 10.5 0.00019 21.2 0.1 6.2 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EAU87746.1 - 7.7e-05 23.0 12.8 0.027 14.9 0.1 6.6 8 1 1 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 EAU87746.1 - 0.00049 19.5 0.1 0.24 10.7 0.0 3.5 3 1 0 3 3 3 1 CLASP N terminal Nucleoporin_FG PF13634.1 EAU87746.1 - 0.0017 18.5 11.2 0.0042 17.2 7.8 1.6 1 0 0 1 1 1 1 Nucleoporin FG repeat region Arm PF00514.18 EAU87746.1 - 0.012 15.3 4.8 4.7 7.1 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EAU87746.1 - 0.047 12.6 0.4 0.37 9.7 0.1 2.3 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Sec7_N PF12783.2 EAU87746.1 - 0.06 12.7 0.6 0.8 9.1 0.1 2.9 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Glyco_hydro_30 PF02055.11 EAU87747.2 - 2.7e-17 62.1 0.0 3.7e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EAU87747.2 - 0.07 12.0 0.0 0.56 9.0 0.0 2.0 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 p450 PF00067.17 EAU87749.2 - 1.3e-66 225.0 0.0 1.5e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1289 PF06945.8 EAU87750.1 - 0.013 14.9 0.2 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) IATP PF04568.7 EAU87751.2 - 1.2e-13 50.9 2.4 1.3e-13 50.8 1.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP CENP-Q PF13094.1 EAU87751.2 - 0.01 15.8 4.7 0.01 15.8 3.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DP PF08781.5 EAU87751.2 - 0.016 14.8 2.7 0.016 14.8 1.9 1.4 1 1 0 1 1 1 0 Transcription factor DP Bap31 PF05529.7 EAU87751.2 - 0.06 12.8 7.9 0.066 12.6 5.5 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF4140 PF13600.1 EAU87751.2 - 0.47 10.9 6.3 0.56 10.6 4.4 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.10 EAU87751.2 - 0.74 9.3 6.7 1 8.8 4.7 1.4 1 1 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.1 EAU87751.2 - 1 8.2 4.0 1.1 8.1 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.4 EAU87751.2 - 9.6 6.2 6.8 18 5.3 4.7 1.6 1 1 0 1 1 1 0 Haemolysin XhlA ATP_sub_h PF10775.4 EAU87752.1 - 2.6e-25 87.9 0.5 3.9e-25 87.3 0.4 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EAU87752.1 - 0.0074 16.1 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 RNA_pol PF00940.14 EAU87753.2 - 2.2e-162 540.1 0.0 3e-162 539.7 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EAU87753.2 - 2.1e-79 267.1 3.1 2.1e-79 267.1 2.1 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 EAU87753.2 - 0.00046 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family DUF3624 PF12292.3 EAU87754.2 - 8.8 6.8 6.1 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) BCS1_N PF08740.6 EAU87757.2 - 4.4e-20 72.0 0.2 1.2e-19 70.6 0.2 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EAU87757.2 - 3.3e-18 66.1 0.0 7.9e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU87757.2 - 0.00048 20.9 0.5 0.0017 19.1 0.2 2.3 2 1 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EAU87757.2 - 0.0046 16.5 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAU87757.2 - 0.013 15.6 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EAU87757.2 - 0.022 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EAU87757.2 - 0.041 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU87757.2 - 0.048 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EAU87757.2 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAU87757.2 - 0.071 12.8 0.0 0.26 11.0 0.0 2.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EAU87757.2 - 0.074 11.7 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EAU87757.2 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.1 EAU87757.2 - 0.088 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EAU87757.2 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EAU87757.2 - 0.11 12.8 0.0 0.37 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 EAU87757.2 - 0.16 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EAU87758.2 - 1e-21 77.5 0.0 2.2e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EAU87758.2 - 2.5e-16 59.8 2.7 7.8e-15 54.9 0.1 2.6 3 0 0 3 3 3 1 BCS1 N terminal AAA_11 PF13086.1 EAU87758.2 - 0.0012 18.5 8.0 0.01 15.4 5.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU87758.2 - 0.0022 17.7 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EAU87758.2 - 0.022 13.8 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.7 EAU87758.2 - 0.037 13.0 0.0 0.074 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EAU87758.2 - 0.045 13.1 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EAU87758.2 - 0.072 13.0 0.0 0.2 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EAU87758.2 - 0.11 12.6 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2992 PF11208.3 EAU87758.2 - 0.12 12.2 10.6 0.21 11.5 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) IncFII_repA PF02387.10 EAU87758.2 - 0.73 8.9 6.1 1.2 8.2 4.3 1.2 1 0 0 1 1 1 0 IncFII RepA protein family NARP1 PF12569.3 EAU87758.2 - 6.7 5.3 16.4 9.3 4.8 11.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_17 PF13207.1 EAU87758.2 - 8.5 7.2 8.9 60 4.4 5.1 2.9 2 1 0 2 2 1 0 AAA domain F-box-like PF12937.2 EAU87759.2 - 0.0049 16.5 0.0 0.96 9.2 0.0 3.3 2 1 0 2 2 2 1 F-box-like DUF4470 PF14737.1 EAU87759.2 - 0.11 12.3 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) Plasmod_MYXSPDY PF07981.6 EAU87759.2 - 0.11 12.2 0.2 0.31 10.7 0.1 1.8 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY adh_short PF00106.20 EAU87762.2 - 4.4e-24 85.2 0.5 6.4e-24 84.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU87762.2 - 5.4e-21 75.4 0.5 7.3e-21 75.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU87762.2 - 2.2e-11 43.7 0.5 5.2e-11 42.5 0.3 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EAU87762.2 - 4.6e-08 33.2 0.3 8.8e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EAU87762.2 - 3.8e-06 26.5 0.1 7e-06 25.6 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EAU87762.2 - 0.00018 20.8 0.1 0.00032 20.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 EAU87762.2 - 0.00065 19.4 1.0 0.0016 18.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EAU87762.2 - 0.0013 17.6 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EAU87762.2 - 0.0091 14.7 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EAU87762.2 - 0.012 14.5 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 EAU87762.2 - 0.071 13.0 0.1 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 EAU87762.2 - 0.081 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein RRM_1 PF00076.17 EAU87764.1 - 2.7e-14 52.5 0.1 2.6e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU87764.1 - 8.1e-08 32.1 0.0 0.00021 21.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU87764.1 - 4.5e-07 29.6 0.0 0.00067 19.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU87764.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ELL PF10390.4 EAU87767.2 - 0.063 12.4 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL ABC1 PF03109.11 EAU87768.2 - 2.2e-23 82.4 0.0 1.2e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 ABC1 family SR-25 PF10500.4 EAU87768.2 - 2.2 7.6 16.1 0.19 11.1 0.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_C48 PF02902.14 EAU87769.2 - 2.3e-09 37.1 0.0 4.4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Nucleoplasmin PF03066.10 EAU87772.2 - 2.9 7.4 6.5 0.72 9.3 2.5 1.6 2 0 0 2 2 2 0 Nucleoplasmin DUF1488 PF07369.6 EAU87773.2 - 0.36 10.6 3.9 5.4 6.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) eIF3g PF12353.3 EAU87775.2 - 0.026 14.4 1.5 0.072 12.9 1.1 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.18 EAU87775.2 - 0.96 9.4 4.0 0.31 11.0 0.9 1.6 2 0 0 2 2 2 0 Zinc knuckle Ndr PF03096.9 EAU87782.2 - 0.049 12.0 3.0 0.052 12.0 1.3 1.5 2 0 0 2 2 2 0 Ndr family Peptidase_C80 PF11713.3 EAU87782.2 - 0.1 12.4 0.9 0.35 10.6 0.2 2.0 2 0 0 2 2 2 0 Peptidase C80 family DUF334 PF03904.8 EAU87782.2 - 0.16 11.2 6.9 0.28 10.4 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DUF1484 PF07363.6 EAU87782.2 - 0.26 11.6 5.6 0.58 10.5 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1484) DUF3584 PF12128.3 EAU87782.2 - 1.5 6.0 26.5 0.15 9.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) COG5 PF10392.4 EAU87782.2 - 1.7 8.6 11.5 2 8.3 1.7 2.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 NOZZLE PF08744.5 EAU87783.2 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Plant transcription factor NOZZLE EF1_GNE PF00736.14 EAU87784.1 - 5.7e-31 106.0 2.7 5.7e-31 106.0 1.9 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EAU87784.1 - 2.1e-12 46.9 5.5 2.1e-12 46.9 3.8 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EAU87784.1 - 0.00017 22.0 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU87784.1 - 0.011 15.7 0.3 0.064 13.2 0.0 2.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU87784.1 - 0.013 15.3 0.2 0.21 11.4 0.1 2.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NUDIX PF00293.23 EAU87791.2 - 4.6e-10 39.2 0.0 1.2e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain CsgE PF10627.4 EAU87791.2 - 0.11 12.3 0.1 17 5.2 0.0 2.2 2 0 0 2 2 2 0 Curli assembly protein CsgE WD40 PF00400.27 EAU87793.2 - 2.3e-06 27.2 9.2 0.12 12.2 0.2 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3521 PF12035.3 EAU87793.2 - 0.015 15.1 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) eIF2A PF08662.6 EAU87793.2 - 0.022 14.4 0.4 30 4.2 0.0 3.6 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EAU87794.2 - 4.8e-14 51.6 1.9 1.9e-06 27.5 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EAU87794.2 - 0.021 14.3 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.12 EAU87796.2 - 2e-47 161.4 0.0 3.1e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU87796.2 - 5.5e-39 133.8 0.0 1.4e-27 96.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.17 EAU87796.2 - 0.0017 17.7 0.1 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EAU87796.2 - 0.031 13.3 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.1 EAU87800.2 - 5.6e-15 55.0 0.5 0.00023 21.0 0.0 6.2 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EAU87800.2 - 1.9e-11 43.4 0.1 0.0073 15.9 0.0 5.7 1 1 6 7 7 7 4 TPR repeat TPR_2 PF07719.12 EAU87800.2 - 2.4e-09 36.3 0.1 1.9 8.6 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat NACHT PF05729.7 EAU87800.2 - 2.2e-07 30.6 0.1 1e-06 28.4 0.0 2.2 2 1 0 2 2 2 1 NACHT domain TPR_16 PF13432.1 EAU87800.2 - 3.1e-06 27.7 8.1 1.4 9.6 0.0 7.0 6 2 1 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU87800.2 - 2.8e-05 24.3 10.3 14 6.6 0.0 8.3 7 1 2 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAU87800.2 - 4.5e-05 22.9 0.2 6.7 6.7 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_22 PF13401.1 EAU87800.2 - 5.6e-05 23.2 0.0 0.00029 20.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.23 EAU87800.2 - 8e-05 22.0 0.5 8 6.2 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.1 EAU87800.2 - 0.00023 21.2 0.1 0.00023 21.2 0.0 3.8 3 3 1 5 5 4 1 AAA ATPase domain NB-ARC PF00931.17 EAU87800.2 - 0.00027 19.9 0.0 0.00053 18.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 EAU87800.2 - 0.00093 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAU87800.2 - 0.0021 18.2 0.0 0.009 16.2 0.0 2.1 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TPR_5 PF12688.2 EAU87800.2 - 0.0032 17.4 0.3 0.85 9.6 0.0 2.9 2 0 0 2 2 2 1 Tetratrico peptide repeat RNA_helicase PF00910.17 EAU87800.2 - 0.0047 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 EAU87800.2 - 0.012 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 EAU87800.2 - 0.084 12.6 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PG_binding_1 PF01471.13 EAU87800.2 - 0.094 12.7 0.0 2.2 8.3 0.0 3.2 3 0 0 3 3 3 0 Putative peptidoglycan binding domain Terpene_synth_C PF03936.11 EAU87802.1 - 1.8e-13 50.3 0.1 2.4e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Fmp27_SW PF10305.4 EAU87802.1 - 0.029 14.8 0.1 0.29 11.5 0.0 2.5 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain Herpes_UL14 PF03580.9 EAU87802.1 - 0.031 14.0 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ANTAR PF03861.9 EAU87802.1 - 0.036 13.6 0.1 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 ANTAR domain Aldo_ket_red PF00248.16 EAU87803.1 - 4.2e-50 170.1 0.0 4.9e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RINGv PF12906.2 EAU87804.1 - 6.6e-07 29.2 7.8 1.2e-06 28.4 5.4 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EAU87804.1 - 0.00056 19.6 5.9 0.001 18.8 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAU87804.1 - 0.0008 19.4 4.0 0.0015 18.5 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EAU87804.1 - 0.02 14.8 4.8 0.038 13.9 3.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 EAU87804.1 - 0.082 12.7 0.9 0.2 11.5 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EAU87804.1 - 0.16 12.0 4.4 0.4 10.7 3.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.4 EAU87804.1 - 0.99 8.0 4.8 1.6 7.4 3.3 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-C3HC4 PF00097.20 EAU87804.1 - 2.3 7.9 7.3 4.1 7.1 5.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-primase PF09329.6 EAU87805.2 - 1.9e-11 43.3 3.4 3.4e-11 42.5 2.4 1.4 1 0 0 1 1 1 1 Primase zinc finger Vfa1 PF08432.5 EAU87805.2 - 4.1 7.4 9.0 1.6 8.6 1.4 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 ASF1_hist_chap PF04729.8 EAU87806.1 - 3.5e-61 205.3 0.0 4.1e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGEF PF00617.14 EAU87807.1 - 2.1e-30 105.8 0.0 4e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EAU87807.1 - 2.8e-11 43.4 0.3 9e-11 41.8 0.2 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif GTP_EFTU PF00009.22 EAU87810.1 - 1.4e-37 128.9 0.0 2.4e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EAU87810.1 - 2.2e-35 120.5 0.5 5.4e-35 119.3 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EAU87810.1 - 2.7e-11 43.4 0.2 2.7e-11 43.4 0.2 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAU87810.1 - 0.02 14.8 0.0 0.051 13.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SIR2 PF02146.12 EAU87811.1 - 7.9e-28 97.3 0.0 6.5e-26 91.1 0.0 2.9 1 1 0 1 1 1 1 Sir2 family CBM_1 PF00734.13 EAU87811.1 - 0.11 12.1 2.5 3.9 7.2 0.4 2.6 2 0 0 2 2 2 0 Fungal cellulose binding domain p450 PF00067.17 EAU87812.2 - 1.6e-66 224.7 0.0 7.1e-62 209.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 PP28 PF10252.4 EAU87813.2 - 5.3e-25 87.2 16.7 5.3e-25 87.2 11.6 2.7 2 2 0 2 2 2 2 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 EAU87813.2 - 1.1 7.6 29.2 1.4 7.2 20.2 1.1 1 0 0 1 1 1 0 Daxx Family Complex1_LYR PF05347.10 EAU87814.1 - 7.2e-11 41.7 0.9 1.3e-10 40.8 0.6 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAU87814.1 - 8.8e-09 35.4 0.4 1.5e-08 34.7 0.3 1.4 1 0 0 1 1 1 1 Complex1_LYR-like F-box-like PF12937.2 EAU87817.1 - 2e-08 33.8 1.5 6.6e-08 32.1 1.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU87817.1 - 0.00045 19.7 2.9 0.0013 18.2 2.0 1.8 1 0 0 1 1 1 1 F-box domain ArsR PF09824.4 EAU87820.1 - 0.061 12.6 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator CcmD PF04995.9 EAU87820.1 - 0.075 12.7 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) BatA PF07584.6 EAU87820.1 - 0.09 12.9 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal AHSA1 PF08327.6 EAU87820.1 - 0.1 12.6 0.1 0.43 10.6 0.1 1.9 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein Fes1 PF08609.5 EAU87822.1 - 7.3e-25 87.2 1.9 1.6e-24 86.1 1.3 1.6 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.1 EAU87822.1 - 7.3e-05 23.1 0.7 0.033 14.6 0.1 3.1 2 1 1 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 EAU87822.1 - 8.3e-05 22.8 0.5 0.0016 18.6 0.1 3.0 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.17 EAU87822.1 - 0.00052 19.8 0.0 0.1 12.7 0.1 3.8 4 0 0 4 4 4 1 HEAT repeat TAN PF11640.3 EAU87822.1 - 0.062 13.0 0.4 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair Glyco_hydro_67N PF03648.9 EAU87823.2 - 0.072 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus 60KD_IMP PF02096.15 EAU87824.1 - 1.3e-31 109.8 0.4 2.1e-31 109.1 0.3 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein DUF106 PF01956.11 EAU87824.1 - 0.018 14.5 1.3 0.026 14.0 0.1 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF106 ABC2_membrane_3 PF12698.2 EAU87824.1 - 0.049 12.6 3.3 0.07 12.1 2.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DAZAP2 PF11029.3 EAU87826.1 - 0.13 12.6 1.0 0.19 12.1 0.7 1.4 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) DUF2024 PF09630.5 EAU87832.1 - 0.043 13.5 0.0 0.12 12.0 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) F-box-like PF12937.2 EAU87834.2 - 0.049 13.3 1.2 0.1 12.3 0.0 2.2 3 0 0 3 3 3 0 F-box-like F-box PF00646.28 EAU87834.2 - 0.36 10.5 5.2 4.7 6.9 0.1 3.9 4 0 0 4 4 4 0 F-box domain Ferritin_2 PF13668.1 EAU87835.1 - 3.2e-26 91.8 0.1 4.7e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 EAU87836.1 - 3.4e-34 117.7 0.1 4.6e-34 117.3 0.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain ICMT PF04140.9 EAU87837.2 - 2.6e-11 43.5 0.2 2.6e-11 43.5 0.2 2.4 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EAU87837.2 - 6.4e-10 39.0 0.6 1.4e-08 34.7 0.2 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EAU87837.2 - 0.00025 19.7 0.5 0.00035 19.2 0.1 1.4 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family CoA_binding_3 PF13727.1 EAU87837.2 - 0.42 10.4 4.7 0.24 11.2 1.4 1.9 2 0 0 2 2 2 0 CoA-binding domain MFS_1 PF07690.11 EAU87838.2 - 7.8e-22 77.4 36.5 1.7e-14 53.3 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU87838.2 - 1.4e-18 66.7 17.3 1.1e-17 63.8 12.0 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter GST_N_3 PF13417.1 EAU87839.1 - 5.3e-11 42.5 0.1 2.2e-10 40.5 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU87839.1 - 1.9e-06 27.7 0.0 3.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EAU87839.1 - 5.9e-06 26.1 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU87839.1 - 0.00041 20.1 0.1 0.00072 19.4 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU87839.1 - 0.00056 20.3 0.1 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF223 PF02721.9 EAU87845.2 - 0.045 13.8 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF223 PI31_Prot_C PF08577.6 EAU87849.2 - 0.12 13.0 3.1 0.14 12.7 0.1 2.7 1 1 3 4 4 4 0 PI31 proteasome regulator DLH PF01738.13 EAU87852.2 - 5.1e-19 68.4 0.1 6.1e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU87852.2 - 5.1e-06 26.3 0.0 8.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU87852.2 - 1.7e-05 24.8 0.1 1.7e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family GRP PF07172.6 EAU87852.2 - 0.0041 17.5 11.9 0.0074 16.7 8.2 1.4 1 0 0 1 1 1 1 Glycine rich protein family DUF3270 PF11674.3 EAU87852.2 - 0.064 13.2 1.0 0.11 12.5 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Cuticle_3 PF11018.3 EAU87852.2 - 0.088 12.9 1.9 0.15 12.1 1.3 1.3 1 0 0 1 1 1 0 Pupal cuticle protein C1 PAE PF03283.8 EAU87852.2 - 0.1 11.2 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Pectinacetylesterase CorA PF01544.13 EAU87853.1 - 0.065 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CoA_trans PF01144.18 EAU87853.1 - 0.085 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Coenzyme A transferase DUF1059 PF06348.6 EAU87853.1 - 0.15 11.9 0.3 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) LSM PF01423.17 EAU87855.2 - 1e-15 57.0 0.3 1.1e-15 56.8 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAU87855.2 - 0.00019 21.2 0.1 0.00027 20.7 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Peptidase_M43 PF05572.8 EAU87856.2 - 9.7e-18 64.2 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EAU87856.2 - 0.00012 22.6 0.0 0.00025 21.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU87856.2 - 0.00019 21.5 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU87856.2 - 0.00021 21.2 0.2 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU87856.2 - 0.00028 20.4 0.0 0.00081 18.9 0.0 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87856.2 - 0.023 14.4 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.3 EAU87856.2 - 0.027 13.7 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1996 PF09362.5 EAU87857.2 - 1.6e-71 240.7 0.2 2e-71 240.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU87857.2 - 1.3e-11 43.9 12.4 1.3e-11 43.9 8.6 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Hydrophobin PF01185.13 EAU87858.1 - 2.3e-21 76.0 5.8 3e-21 75.6 4.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ras PF00071.17 EAU87860.2 - 1.6e-05 24.3 0.0 0.00016 21.0 0.0 2.4 2 1 0 2 2 2 1 Ras family Miro PF08477.8 EAU87860.2 - 0.06 13.8 0.0 0.75 10.3 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Peptidase_C14 PF00656.17 EAU87861.2 - 2.3e-34 119.2 0.0 3.4e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Glyco_hydro_28 PF00295.12 EAU87862.2 - 7.6e-42 143.4 13.7 1e-41 142.9 9.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CLCA_N PF08434.6 EAU87863.2 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel CLCA_N PF08434.6 EAU87864.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel DLH PF01738.13 EAU87866.1 - 1.5e-18 66.9 0.1 1.7e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU87866.1 - 2e-06 27.6 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU87866.1 - 0.00028 20.8 0.1 0.00028 20.8 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family GPI-anchored PF10342.4 EAU87867.2 - 0.0024 18.3 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pheromone PF08015.6 EAU87868.2 - 0.025 15.3 0.7 0.039 14.7 0.5 1.5 1 1 0 1 1 1 0 Fungal mating-type pheromone DUF680 PF05079.7 EAU87868.2 - 1.3 9.5 3.9 2 8.9 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF680) Glyco_hydro_30 PF02055.11 EAU87869.2 - 7.9e-13 47.4 0.4 1.2e-07 30.2 0.0 2.3 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EAU87869.2 - 2.4e-07 30.0 4.1 1.9e-05 23.7 0.0 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 SnoaL_2 PF12680.2 EAU87870.1 - 0.0012 19.2 1.6 0.0017 18.6 1.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EAU87870.1 - 0.0067 16.0 0.7 0.069 12.7 0.5 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase UCR_hinge PF02320.11 EAU87873.2 - 6.6e-09 35.5 3.7 1.2e-08 34.7 2.6 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Bindin PF02084.10 EAU87873.2 - 0.57 10.1 1.9 0.85 9.6 1.3 1.2 1 0 0 1 1 1 0 Bindin DLH PF01738.13 EAU87874.2 - 2.8e-18 66.0 0.0 3.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU87874.2 - 4.9e-06 26.3 0.0 8.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU87874.2 - 0.0003 20.7 0.9 0.00052 19.9 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ricin_B_lectin PF00652.17 EAU87875.1 - 1.6e-25 89.5 0.2 1.9e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU87875.1 - 1.1e-17 64.2 0.1 2.7e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SnoaL_2 PF12680.2 EAU87876.1 - 9.6e-05 22.7 0.2 0.00014 22.2 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EAU87876.1 - 0.023 14.2 0.1 0.14 11.7 0.1 2.0 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase PMSR PF01625.16 EAU87877.1 - 5.8e-59 198.4 0.2 7.1e-59 198.1 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Transaldolase PF00923.14 EAU87878.1 - 1.6e-55 188.2 0.0 6.2e-52 176.5 0.0 2.4 2 1 0 2 2 2 2 Transaldolase Phg_2220_C PF09524.5 EAU87879.1 - 0.092 12.7 0.0 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) MIP-T3 PF10243.4 EAU87881.1 - 0.00013 20.6 32.4 0.00013 20.6 22.4 4.4 2 1 1 3 3 3 1 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 EAU87881.1 - 0.0033 16.8 38.2 0.0033 16.8 26.5 6.2 4 2 2 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Baculo_PEP_C PF04513.7 EAU87881.1 - 0.0044 16.8 0.4 0.0044 16.8 0.3 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Gp58 PF07902.6 EAU87881.1 - 0.04 12.1 7.4 0.077 11.2 5.1 1.4 1 0 0 1 1 1 0 gp58-like protein Tht1 PF04163.7 EAU87881.1 - 2.1 6.6 1.7 3.7 5.8 1.2 1.3 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Glyco_hydro_38 PF01074.17 EAU87883.2 - 1.2e-83 280.5 0.1 1.9e-83 279.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EAU87883.2 - 4.1e-58 197.2 0.0 6e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EAU87883.2 - 2.4e-14 53.2 0.1 5.6e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Tuberin PF03542.11 EAU87883.2 - 0.11 11.5 0.0 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Tuberin zf-PARP PF00645.13 EAU87884.2 - 0.078 13.2 0.4 0.078 13.2 0.3 1.9 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Thymidylat_synt PF00303.14 EAU87885.1 - 1.2e-110 368.7 0.0 1.4e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase NAD_binding_4 PF07993.7 EAU87887.2 - 5.2e-32 110.7 0.0 1e-31 109.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EAU87887.2 - 4.8e-09 36.0 0.0 1.2e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.23 EAU87887.2 - 6.1e-07 28.1 0.1 4.7e-06 25.2 0.0 2.4 1 1 1 2 2 2 1 AMP-binding enzyme 3Beta_HSD PF01073.14 EAU87887.2 - 0.005 15.5 0.0 0.087 11.5 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EAU87887.2 - 0.088 12.7 0.3 0.26 11.1 0.2 1.9 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EAU87887.2 - 0.14 11.7 0.5 1.4 8.5 0.3 2.3 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 EAU87887.2 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family GMC_oxred_N PF00732.14 EAU87893.2 - 6.3e-62 209.3 0.0 7.9e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87893.2 - 4e-33 114.7 0.0 7.3e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU87893.2 - 4.1e-05 23.5 0.2 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU87893.2 - 0.00027 19.9 0.1 0.0006 18.8 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU87893.2 - 0.0013 17.7 0.1 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU87893.2 - 0.004 16.0 0.2 0.035 12.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EAU87893.2 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EAU87893.2 - 0.21 10.1 0.2 1.6 7.2 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.14 EAU87895.1 - 7.3e-65 219.0 0.0 9.3e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87895.1 - 6.6e-35 120.5 0.0 1.3e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU87895.1 - 1.6e-05 24.8 0.1 0.00035 20.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU87895.1 - 0.00012 21.0 0.0 0.025 13.4 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAU87895.1 - 0.00021 20.3 1.0 0.0013 17.6 0.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU87895.1 - 0.0009 18.2 0.1 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EAU87895.1 - 0.049 12.0 0.0 0.067 11.6 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.13 EAU87895.1 - 0.054 13.4 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 EAU87895.1 - 0.077 11.6 0.9 0.3 9.6 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase Peptidase_M28 PF04389.12 EAU87896.1 - 1.2e-31 109.8 0.0 1.8e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAU87896.1 - 5.8e-13 48.3 0.5 1.3e-12 47.2 0.2 1.8 2 0 0 2 2 2 1 PA domain GMC_oxred_N PF00732.14 EAU87897.2 - 5.4e-61 206.3 0.0 7.8e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87897.2 - 1.4e-30 106.4 0.0 2.3e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU87897.2 - 0.00021 21.2 0.0 0.00056 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU87897.2 - 0.00041 19.3 0.0 0.00085 18.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EAU87897.2 - 0.00069 18.6 0.1 0.0011 18.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU87897.2 - 0.015 14.1 0.1 0.052 12.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EAU87897.2 - 0.035 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EAU87897.2 - 0.046 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EAU87898.1 - 7.1e-64 215.7 0.0 8.9e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87898.1 - 9.8e-35 119.9 0.0 1.5e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EAU87898.1 - 0.0058 15.6 0.1 0.0097 14.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EAU87898.1 - 0.011 15.7 0.0 0.053 13.5 0.0 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU87898.1 - 0.022 13.6 0.2 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_N PF00732.14 EAU87899.2 - 7.1e-65 219.0 0.0 8.9e-65 218.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87899.2 - 2.9e-36 124.9 0.0 4.6e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EAU87899.2 - 0.0014 17.6 0.1 0.0022 16.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU87899.2 - 0.0075 15.1 0.1 0.54 9.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EAU87899.2 - 0.013 15.5 0.1 0.045 13.7 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HUN PF08729.5 EAU87900.1 - 1e-11 44.5 0.2 1e-11 44.5 0.2 2.8 3 0 0 3 3 3 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 EAU87900.1 - 0.00015 21.5 0.0 0.00015 21.5 0.0 3.3 3 1 0 3 3 3 1 Ubinuclein conserved middle domain Nop14 PF04147.7 EAU87900.1 - 0.29 9.0 30.1 0.53 8.1 20.9 1.3 1 0 0 1 1 1 0 Nop14-like family GMC_oxred_N PF00732.14 EAU87901.2 - 3e-64 217.0 0.0 3.8e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU87901.2 - 3.3e-30 105.2 0.0 4.9e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EAU87901.2 - 0.00071 18.5 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EAU87901.2 - 0.0027 16.6 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EAU87901.2 - 0.044 12.8 0.0 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EAU87901.2 - 0.091 12.8 0.1 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Xpo1 PF08389.7 EAU87903.1 - 1.3e-09 38.1 1.6 3.5e-07 30.2 0.0 4.0 4 1 1 5 5 5 2 Exportin 1-like protein CRM1_C PF08767.6 EAU87903.1 - 0.00014 20.9 0.0 0.0065 15.4 0.0 2.3 2 0 0 2 2 2 2 CRM1 C terminal IBN_N PF03810.14 EAU87903.1 - 0.00019 21.3 0.1 0.00078 19.3 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Kdo PF06293.9 EAU87904.2 - 5e-05 22.4 0.0 9e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EAU87904.2 - 0.0017 17.7 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH_6_hur PF04655.9 EAU87904.2 - 0.004 16.3 0.2 0.0098 15.0 0.0 1.7 2 0 0 2 2 2 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.18 EAU87904.2 - 0.013 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family HIT PF01230.18 EAU87904.2 - 0.064 13.7 0.6 0.73 10.3 0.0 2.4 2 0 0 2 2 2 0 HIT domain Choline_kinase PF01633.15 EAU87904.2 - 0.18 11.3 0.0 0.52 9.8 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Herpes_gE PF02480.11 EAU87906.1 - 0.046 11.9 0.0 0.066 11.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Lysis_S PF04971.7 EAU87906.1 - 0.048 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Lysis protein S ACPS PF01648.15 EAU87907.1 - 0.0038 17.0 0.0 0.0079 16.0 0.0 1.6 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_M16 PF00675.15 EAU87908.1 - 3.2e-22 78.9 0.1 5.8e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAU87908.1 - 9.3e-07 28.6 0.0 2.8e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase M16 inactive domain NST1 PF13945.1 EAU87909.2 - 9.6e-60 201.9 1.2 9.6e-60 201.9 0.9 5.3 3 1 3 6 6 6 1 Salt tolerance down-regulator Lipase_GDSL_2 PF13472.1 EAU87910.1 - 1e-13 51.7 0.6 2e-13 50.8 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU87910.1 - 2.4e-05 24.2 1.7 2.4e-05 24.2 1.1 2.5 3 1 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EAU87910.1 - 0.0031 17.2 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HEAT_2 PF13646.1 EAU87915.2 - 3.7e-16 59.1 23.1 0.00021 21.4 0.2 8.5 5 2 4 9 9 9 4 HEAT repeats HEAT PF02985.17 EAU87915.2 - 3.1e-15 54.8 16.1 0.018 15.0 0.1 10.2 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.1 EAU87915.2 - 1.4e-05 25.4 19.2 1.4 9.4 0.1 7.9 7 1 1 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAU87915.2 - 7.9e-05 22.9 0.0 4 7.8 0.0 5.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EAU87915.2 - 0.0004 19.2 0.1 2.8 6.5 0.0 4.6 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal DUF4013 PF13197.1 EAU87915.2 - 0.36 10.1 3.5 0.64 9.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) HEAT_PBS PF03130.11 EAU87915.2 - 0.66 10.6 4.5 18 6.1 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat F-box-like PF12937.2 EAU87917.2 - 0.026 14.2 0.0 0.15 11.8 0.0 2.4 1 1 0 1 1 1 0 F-box-like AMP-binding PF00501.23 EAU87919.1 - 4e-87 292.3 0.0 5.4e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU87919.1 - 0.047 14.6 0.1 0.13 13.1 0.0 1.8 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain LRR_4 PF12799.2 EAU87920.2 - 0.0014 18.1 0.0 0.73 9.5 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU87920.2 - 0.0057 16.3 0.9 1.2 8.9 0.2 3.8 4 0 0 4 4 4 1 Leucine rich repeat AMP-binding PF00501.23 EAU87921.1 - 2.3e-87 293.0 0.0 3.2e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU87921.1 - 9.6e-05 23.2 0.3 0.012 16.5 0.1 2.8 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain FAINT PF04385.10 EAU87921.1 - 0.054 13.3 0.6 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function, DUF529 GATA PF00320.22 EAU87922.1 - 6.5e-26 89.3 19.9 1.6e-15 56.1 2.4 2.7 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 EAU87922.1 - 2e-10 40.0 0.2 4e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 EAU87922.1 - 0.19 11.0 6.7 0.17 11.2 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 EAU87922.1 - 2.3 7.8 8.4 5.5 6.6 0.5 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zinc_ribbon_5 PF13719.1 EAU87922.1 - 2.5 7.7 4.9 3.6 7.2 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EAU87922.1 - 2.9 7.9 8.0 13 5.7 0.7 2.9 2 1 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 EAU87922.1 - 4.9 6.9 5.9 3.2 7.5 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 EAU87922.1 - 8.3 6.5 7.8 0.43 10.6 0.6 2.4 3 0 0 3 3 3 0 zinc-finger DZR PF12773.2 EAU87922.1 - 9.3 6.1 10.7 73 3.3 0.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 EAU87922.1 - 9.9 5.7 10.8 0.34 10.4 0.4 2.6 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 AMP-binding PF00501.23 EAU87926.1 - 2.4e-27 95.3 0.0 1.1e-26 93.1 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme Tyr-DNA_phospho PF06087.7 EAU87927.2 - 2.3e-62 211.0 0.0 3.7e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EAU87927.2 - 8.1e-06 25.5 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 EAU87927.2 - 0.00013 21.2 10.4 0.00055 19.2 1.5 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif NAD_binding_10 PF13460.1 EAU87928.2 - 1.9e-28 99.6 0.1 2.3e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAU87928.2 - 3.7e-05 23.2 0.0 5.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EAU87928.2 - 0.00029 21.1 0.1 0.0005 20.3 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EAU87928.2 - 0.0043 16.6 0.1 0.0087 15.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ldh_1_N PF00056.18 EAU87928.2 - 0.022 14.5 0.3 0.041 13.6 0.2 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EAU87928.2 - 0.041 12.8 0.0 0.12 11.2 0.0 1.7 1 1 1 2 2 2 0 Male sterility protein NmrA PF05368.8 EAU87928.2 - 0.056 12.6 0.3 0.079 12.1 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.13 EAU87928.2 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 EAU87928.2 - 0.076 12.9 0.1 0.13 12.1 0.1 1.4 1 1 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.16 EAU87928.2 - 0.077 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EAU87928.2 - 0.13 12.4 0.2 0.26 11.5 0.1 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Glyco_hydro_62 PF03664.8 EAU87930.1 - 9.9e-78 260.9 2.6 1.2e-77 260.6 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 EAU87930.1 - 2.2e-14 52.7 5.6 5.5e-14 51.5 3.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.8 EAU87931.2 - 1.3e-71 240.9 0.5 1.5e-71 240.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Pkinase PF00069.20 EAU87932.2 - 2.6e-35 121.8 0.0 3.4e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU87932.2 - 3.5e-21 75.4 0.0 4.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU87932.2 - 0.051 12.5 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Peptidase_M43 PF05572.8 EAU87934.1 - 2.7e-19 69.3 0.0 5.2e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU87934.1 - 2e-07 31.1 0.0 3.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU87934.1 - 2.2e-06 28.2 0.1 3.5e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU87934.1 - 0.00033 20.7 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU87934.1 - 0.0044 16.5 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87934.1 - 0.0051 16.5 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M57 PF12388.3 EAU87934.1 - 0.008 15.5 1.8 0.057 12.7 0.2 2.1 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 EAU87934.1 - 0.043 12.6 1.7 0.063 12.1 1.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M7 PF02031.11 EAU87934.1 - 0.1 12.3 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family p450 PF00067.17 EAU87935.2 - 3.8e-43 147.6 0.0 4.4e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU87936.1 - 4.3e-41 140.9 0.0 5.7e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU87937.1 - 2.7e-49 167.9 0.0 3.2e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU87938.2 - 3.8e-24 85.0 0.0 2.2e-21 75.9 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 HEAT_PBS PF03130.11 EAU87938.2 - 0.075 13.5 0.0 0.42 11.2 0.0 2.2 1 1 1 2 2 2 0 PBS lyase HEAT-like repeat Glyco_hydro_18 PF00704.23 EAU87939.1 - 2.3e-52 178.5 2.9 4.8e-51 174.2 2.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PX PF00787.19 EAU87939.1 - 3.4e-13 49.3 0.0 5.7e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 PX domain GHL6 PF14871.1 EAU87939.1 - 0.096 12.7 0.1 0.83 9.6 0.0 2.4 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase 6 Acetyltransf_7 PF13508.1 EAU87941.2 - 1.4e-06 28.3 0.0 2.6e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU87941.2 - 1.2e-05 25.1 0.3 0.0013 18.5 0.1 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU87941.2 - 7.9e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EAU87941.2 - 0.018 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAU87941.2 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EAU87942.1 - 5.8e-05 23.1 0.0 9.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU87942.1 - 0.0015 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EAU87942.1 - 0.015 15.1 0.1 0.46 10.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAU87942.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Glyco_hydro_71 PF03659.9 EAU87943.2 - 1.9e-79 266.9 1.7 2.4e-79 266.6 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.14 EAU87943.2 - 5.7e-20 71.0 10.8 1.2e-14 53.9 5.1 2.4 2 0 0 2 2 2 2 WSC domain La PF05383.12 EAU87944.1 - 2e-19 69.1 0.0 7.2e-19 67.3 0.0 2.0 2 0 0 2 2 2 1 La domain RRM_1 PF00076.17 EAU87944.1 - 3.8e-08 32.8 2.5 1.7e-07 30.7 0.4 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU87944.1 - 1.3e-07 31.5 0.1 3.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU87944.1 - 3.3e-07 30.0 0.1 7.5e-06 25.7 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.1 EAU87944.1 - 0.32 10.8 1.6 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) E1-E2_ATPase PF00122.15 EAU87947.2 - 6.9e-22 77.6 0.0 6.9e-22 77.6 0.0 2.5 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EAU87947.2 - 3.6e-16 60.2 0.0 2.4e-15 57.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU87947.2 - 4.8e-11 43.1 0.0 1.1e-10 42.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAU87947.2 - 1.5e-06 28.0 0.1 6.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAU87947.2 - 5e-05 22.9 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Staphylcoagulse PF04022.7 EAU87947.2 - 0.49 9.8 2.8 2.1 7.7 0.6 2.5 2 0 0 2 2 2 0 Staphylocoagulase repeat Velvet PF11754.3 EAU87949.1 - 1.1e-54 185.1 0.3 3.8e-37 127.8 0.0 2.5 2 0 0 2 2 2 2 Velvet factor DNA_pol_lambd_f PF10391.4 EAU87950.2 - 8.8e-21 73.2 0.1 1.9e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DPBB_1 PF03330.13 EAU87950.2 - 6.8e-10 38.8 0.0 1.9e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DNA_pol_B_palm PF14792.1 EAU87950.2 - 2.2e-06 27.6 0.0 3.3e-05 23.8 0.0 2.4 1 1 1 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EAU87950.2 - 0.00054 19.5 0.1 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb BRCT PF00533.21 EAU87950.2 - 0.0066 16.5 0.0 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Methyltransf_23 PF13489.1 EAU87951.1 - 4.5e-15 55.7 0.0 6.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU87951.1 - 3.6e-14 52.6 0.0 1.3e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU87951.1 - 2.5e-10 40.6 0.0 4.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU87951.1 - 3e-07 30.9 0.0 2.2e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU87951.1 - 1.5e-06 28.6 0.0 3.3e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAU87951.1 - 2.5e-06 26.6 0.0 5.7e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EAU87951.1 - 3.3e-06 27.3 0.0 2.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU87951.1 - 1.4e-05 25.0 0.0 6.8e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU87951.1 - 6.7e-05 22.1 0.0 0.00045 19.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EAU87951.1 - 0.0033 17.4 0.0 0.0085 16.0 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.11 EAU87951.1 - 0.053 11.8 0.0 0.068 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EAU87951.1 - 0.094 12.0 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain p450 PF00067.17 EAU87952.2 - 1.8e-43 148.7 0.0 2.4e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EphA2_TM PF14575.1 EAU87952.2 - 0.092 13.1 0.1 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ank_2 PF12796.2 EAU87956.2 - 3.7e-37 126.5 2.1 7.8e-15 54.9 0.0 4.0 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAU87956.2 - 7.7e-35 116.9 11.2 1.4e-08 34.1 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EAU87956.2 - 1.3e-29 101.5 9.8 1.1e-11 44.5 0.1 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU87956.2 - 1.1e-24 86.3 8.3 1.4e-08 34.9 0.1 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU87956.2 - 3.2e-22 76.3 8.6 8.9e-05 22.3 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 EAU87956.2 - 3e-13 49.5 3.3 6.9e-08 32.0 0.6 3.1 2 1 1 3 3 3 2 DHHC palmitoyltransferase EF1G PF00647.14 EAU87957.1 - 3.1e-39 132.9 0.0 5e-39 132.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EAU87957.1 - 2.5e-09 36.9 0.0 6.8e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAU87957.1 - 1.3e-08 34.8 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU87957.1 - 3.4e-07 30.0 0.0 8.2e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU87957.1 - 5.2e-07 30.0 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAU87957.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 EAU87957.1 - 0.46 10.9 9.2 0.22 11.9 4.2 2.1 2 1 1 3 3 3 0 60s Acidic ribosomal protein F-box-like PF12937.2 EAU87958.2 - 2.6e-06 27.0 0.1 9e-06 25.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU87958.2 - 0.0006 19.4 0.5 0.0038 16.8 0.3 2.4 1 1 0 1 1 1 1 F-box domain Peptidase_M43 PF05572.8 EAU87960.1 - 1.2e-20 73.6 0.4 4.2e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EAU87960.1 - 8.5e-05 22.6 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU87960.1 - 0.00016 21.6 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU87960.1 - 0.0011 18.5 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU87960.1 - 0.0057 16.3 0.3 0.01 15.6 0.2 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 EAU87960.1 - 0.017 15.6 0.9 0.044 14.3 0.6 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 EAU87960.1 - 0.032 13.9 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Surf_Ag_VNR PF07244.10 EAU87960.1 - 0.074 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Surface antigen variable number repeat AAA PF00004.24 EAU87961.2 - 1.1e-20 74.2 0.0 1.7e-10 41.1 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EAU87961.2 - 1.4e-09 37.8 1.3 1.2e-05 24.9 0.1 2.6 2 1 1 3 3 3 2 BCS1 N terminal AAA_17 PF13207.1 EAU87961.2 - 8.4e-05 23.3 0.0 0.00032 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU87961.2 - 0.00073 19.2 0.0 0.0022 17.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EAU87961.2 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU87961.2 - 0.0022 18.0 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EAU87961.2 - 0.0065 16.7 0.0 0.029 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EAU87961.2 - 0.0094 15.0 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 EAU87961.2 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAU87961.2 - 0.022 14.5 0.0 0.058 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU87961.2 - 0.024 14.8 0.0 0.07 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAU87961.2 - 0.03 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAU87961.2 - 0.031 13.3 0.0 0.083 11.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 EAU87961.2 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EAU87961.2 - 0.053 12.5 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EAU87961.2 - 0.17 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 EAU87961.2 - 0.26 9.9 0.0 0.4 9.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus ADH_zinc_N PF00107.21 EAU87962.2 - 3.9e-29 100.8 0.2 5.8e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU87962.2 - 1.6e-14 54.8 0.0 2.9e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU87962.2 - 2.3e-10 40.2 0.0 4.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EAU87962.2 - 0.0027 17.2 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EAU87962.2 - 0.056 13.0 0.1 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Cullin_binding PF03556.10 EAU87963.1 - 5.8e-37 126.4 0.1 1.2e-36 125.4 0.0 1.5 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.1 EAU87963.1 - 5.6e-07 28.9 0.1 1.1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain ADH_zinc_N PF00107.21 EAU87971.1 - 2.7e-30 104.5 0.3 4.4e-30 103.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU87971.1 - 1.1e-16 61.8 0.0 2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU87971.1 - 1.8e-12 46.9 0.1 3.3e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EAU87972.2 - 1.3e-39 136.0 0.0 1.7e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU87973.1 - 1.7e-42 145.5 0.0 2e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU87974.2 - 5.8e-40 137.1 0.0 1.6e-39 135.7 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 p450 PF00067.17 EAU87975.2 - 1e-44 152.8 0.0 1.2e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpb5_C PF01191.14 EAU87975.2 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain NACHT PF05729.7 EAU87977.2 - 3.7e-11 42.9 0.0 5.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU87977.2 - 3.1e-07 30.5 0.1 1.1e-06 28.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU87977.2 - 2.9e-06 27.4 0.0 7.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAU87977.2 - 0.00054 19.5 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAU87977.2 - 0.0076 16.4 0.0 0.093 12.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAU87977.2 - 0.03 14.0 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EAU87977.2 - 0.067 14.0 0.2 0.82 10.5 0.1 2.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAU87977.2 - 0.1 12.3 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EAU87977.2 - 0.14 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Peptidase_S8 PF00082.17 EAU87978.1 - 1.6e-55 188.2 0.9 2.4e-55 187.6 0.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EAU87978.1 - 2.1e-28 97.9 0.2 4.2e-28 96.9 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Nucleoplasmin PF03066.10 EAU87978.1 - 0.005 16.3 12.3 0.011 15.2 8.5 1.5 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 EAU87978.1 - 0.035 13.2 5.2 0.06 12.5 3.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 EAU87978.1 - 0.038 11.9 10.3 0.052 11.4 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EAU87978.1 - 0.72 9.4 14.5 1.7 8.1 10.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 EAU87978.1 - 1.3 6.8 9.7 2 6.1 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 EAU87978.1 - 2.3 6.6 17.8 3.3 6.0 12.3 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 EAU87978.1 - 3.7 6.7 11.4 7.3 5.7 7.9 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EAU87978.1 - 3.8 6.1 21.2 7.5 5.1 14.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 EAU87978.1 - 4.9 6.9 11.6 12 5.7 8.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.6 EAU87978.1 - 6.4 6.2 13.6 11 5.4 9.5 1.3 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.1 EAU87978.1 - 8.2 6.0 9.6 16 5.1 6.6 1.4 1 0 0 1 1 1 0 FAM176 family Methyltransf_11 PF08241.7 EAU87979.2 - 2.1e-15 57.0 0.0 4.3e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU87979.2 - 1.2e-10 41.2 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU87979.2 - 2.7e-10 40.6 0.0 8.6e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU87979.2 - 3.7e-10 40.0 0.0 1.4e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU87979.2 - 1.5e-09 37.7 0.0 2e-09 37.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU87979.2 - 4.6e-09 36.8 0.0 9.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EAU87979.2 - 0.00028 20.5 0.0 0.066 12.8 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase MTS PF05175.9 EAU87979.2 - 0.0028 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EAU87979.2 - 0.016 14.4 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 EAU87979.2 - 0.039 13.9 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 EAU87979.2 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase zf-RING_2 PF13639.1 EAU87981.1 - 2.7e-06 27.0 5.0 4.5e-06 26.4 3.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAU87981.1 - 5.4e-05 23.1 6.0 8.9e-05 22.4 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU87981.1 - 0.0039 16.7 3.9 0.0066 16.0 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU87981.1 - 0.017 14.8 3.9 0.028 14.1 2.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EAU87981.1 - 0.022 14.6 6.5 0.04 13.8 4.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2HC5 PF06221.8 EAU87981.1 - 0.49 10.1 4.2 0.94 9.2 2.9 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Aminotran_3 PF00202.16 EAU87983.1 - 3.5e-101 338.4 0.0 7.8e-101 337.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EAU87983.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EAU87983.1 - 0.0072 15.3 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II PEMT PF04191.8 EAU87989.2 - 7.2e-50 167.5 17.1 2.9e-29 101.2 1.3 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase 2OG-FeII_Oxy_2 PF13532.1 EAU87990.2 - 9.6e-05 22.2 0.0 0.00019 21.3 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EAU87991.2 - 1.2e-42 146.0 0.0 1.6e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.19 EAU87992.1 - 9.5e-41 140.3 0.1 1.1e-26 93.9 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAU87992.1 - 4e-11 42.7 0.0 1.5e-10 40.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EAU87992.1 - 0.0035 16.2 0.3 0.0057 15.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EAU87992.1 - 0.0079 15.2 0.9 0.012 14.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EAU87992.1 - 0.015 15.3 0.1 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU87992.1 - 0.016 15.0 0.1 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAU87992.1 - 0.023 13.5 0.2 0.059 12.2 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EAU87992.1 - 0.1 11.0 0.3 0.16 10.4 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF1996 PF09362.5 EAU87993.2 - 7.4e-70 235.2 0.1 9.5e-70 234.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PsaM PF07465.8 EAU87993.2 - 1.8 8.2 3.7 1.6 8.3 0.3 2.1 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) PPR_3 PF13812.1 EAU87994.1 - 9.8e-18 62.9 7.7 9.1e-05 22.4 0.0 7.2 7 0 0 7 7 7 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 EAU87994.1 - 3.6e-10 39.6 0.1 0.026 14.4 0.0 5.2 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.15 EAU87994.1 - 0.00031 20.5 4.8 85 3.4 0.0 7.5 8 0 0 8 8 8 0 PPR repeat Cyclin_N PF00134.18 EAU87995.2 - 0.00023 20.7 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EAU87995.2 - 0.055 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Cyclin p450 PF00067.17 EAU87996.1 - 1.7e-43 148.8 0.0 2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RPW8 PF05659.6 EAU87996.1 - 0.061 12.8 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 HATPase_c_2 PF13581.1 EAU87996.1 - 0.12 12.2 0.0 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain TFIIE_beta PF02186.10 EAU88000.1 - 1.2e-08 34.7 0.3 2.6e-08 33.7 0.1 1.7 2 0 0 2 2 2 1 TFIIE beta subunit core domain Ricin_B_lectin PF00652.17 EAU88001.2 - 3e-09 36.9 0.2 5.5e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU88001.2 - 1.1e-06 28.9 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Yae1_N PF09811.4 EAU88002.1 - 3.7e-12 45.5 3.5 5.7e-12 44.9 2.4 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal F-box-like PF12937.2 EAU88003.2 - 5.3e-08 32.4 0.8 1.5e-07 30.9 0.6 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EAU88003.2 - 0.0067 16.3 0.0 0.18 11.9 0.0 3.3 4 0 0 4 4 4 1 Leucine Rich repeat F-box PF00646.28 EAU88003.2 - 0.021 14.4 0.1 0.069 12.8 0.1 1.9 1 0 0 1 1 1 0 F-box domain Na_H_Exchanger PF00999.16 EAU88004.1 - 2.8e-63 213.7 38.7 3.6e-63 213.3 26.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_43 PF04616.9 EAU88005.2 - 3.1e-29 101.9 2.4 9.4e-28 97.1 1.7 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 TPR_11 PF13414.1 EAU88006.1 - 9.4e-26 89.2 6.6 2.3e-06 27.1 0.2 7.8 3 1 5 8 8 8 7 TPR repeat TPR_12 PF13424.1 EAU88006.1 - 5.5e-24 83.9 7.7 1.8e-05 24.5 0.1 7.9 4 1 4 9 9 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 EAU88006.1 - 1.5e-16 58.7 7.5 0.22 11.3 0.0 9.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.1 EAU88006.1 - 1.1e-14 53.8 26.7 0.0036 17.1 0.3 8.6 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAU88006.1 - 1.6e-14 54.1 17.8 0.00041 20.9 0.8 6.8 4 1 1 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EAU88006.1 - 8.8e-13 47.2 1.7 0.25 10.9 0.0 8.8 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU88006.1 - 1.1e-10 40.8 1.4 0.31 11.3 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU88006.1 - 1.4e-10 40.2 13.3 0.36 10.8 0.0 9.4 9 1 1 10 10 9 1 Tetratricopeptide repeat MIT PF04212.13 EAU88006.1 - 1.2e-07 31.4 0.5 1.8 8.4 0.0 6.3 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain NACHT PF05729.7 EAU88006.1 - 1.4e-06 28.0 0.0 7.2e-06 25.7 0.0 2.4 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU88006.1 - 2.1e-06 27.9 0.0 2.3e-05 24.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain TPR_14 PF13428.1 EAU88006.1 - 1.5e-05 25.1 31.0 1.2 9.9 0.1 9.4 8 2 1 9 9 7 3 Tetratricopeptide repeat NB-ARC PF00931.17 EAU88006.1 - 1.6e-05 23.8 0.0 2.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EAU88006.1 - 0.00021 21.3 5.5 0.00025 21.1 0.0 3.5 3 2 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EAU88006.1 - 0.0019 18.0 0.0 0.0072 16.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_6 PF13174.1 EAU88006.1 - 0.0051 17.1 1.1 20 5.8 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EAU88006.1 - 0.0092 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EAU88006.1 - 0.018 15.2 0.0 0.074 13.2 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA PF00004.24 EAU88006.1 - 0.019 15.1 0.0 0.073 13.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sel1 PF08238.7 EAU88006.1 - 0.046 14.3 0.3 24 5.7 0.0 4.3 5 0 0 5 5 2 0 Sel1 repeat TPR_19 PF14559.1 EAU88006.1 - 0.06 13.7 14.2 25 5.2 0.1 7.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAU88006.1 - 0.07 12.9 0.1 38 4.3 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat PPDK_N PF01326.14 EAU88006.1 - 0.16 11.0 0.9 8.4 5.3 0.2 2.9 1 1 1 2 2 2 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ArsR PF09824.4 EAU88006.1 - 0.17 11.1 0.0 17 4.7 0.0 2.7 2 0 0 2 2 2 0 ArsR transcriptional regulator F-box-like PF12937.2 EAU88007.1 - 9e-13 47.7 1.0 2.2e-12 46.4 0.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAU88007.1 - 0.00014 21.5 1.0 0.67 9.7 0.0 5.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.2 EAU88007.1 - 0.0013 18.3 4.0 0.72 9.5 0.1 5.5 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EAU88007.1 - 0.0014 18.2 0.8 0.0043 16.6 0.6 2.0 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.1 EAU88007.1 - 0.48 10.6 6.7 58 4.2 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 EAU88007.1 - 0.57 10.6 4.4 19 6.0 0.0 5.3 6 1 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EAU88007.1 - 0.66 10.2 5.5 8.4 6.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat DHHA1 PF02272.14 EAU88008.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 DHHA1 domain G-alpha PF00503.15 EAU88009.2 - 4e-110 368.1 0.0 5.5e-110 367.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU88009.2 - 0.00029 20.1 0.7 2 7.6 0.1 3.2 3 0 0 3 3 3 2 ADP-ribosylation factor family Pox_A32 PF04665.7 EAU88009.2 - 0.076 12.2 0.1 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_22 PF13401.1 EAU88009.2 - 0.099 12.7 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain HLH PF00010.21 EAU88010.2 - 1.2e-12 47.2 0.1 2.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GMC_oxred_N PF00732.14 EAU88011.2 - 1e-52 179.1 0.0 1.2e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU88011.2 - 7.3e-34 117.1 0.0 1.2e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU88011.2 - 0.056 13.4 0.7 0.17 11.9 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAU88011.2 - 0.18 10.6 0.1 0.25 10.1 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Bap31 PF05529.7 EAU88016.1 - 8.5e-51 172.1 2.8 1e-50 171.8 1.9 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Apt1 PF10351.4 EAU88016.1 - 0.0053 15.6 0.9 0.0073 15.2 0.6 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Lge1 PF11488.3 EAU88016.1 - 0.01 16.0 1.3 0.018 15.1 0.9 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF89 PF01937.14 EAU88016.1 - 0.023 13.5 0.3 0.029 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 DUF883 PF05957.8 EAU88016.1 - 0.051 13.9 2.8 0.11 12.9 1.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Cortexin PF11057.3 EAU88016.1 - 1.9 8.1 4.3 8.3 6.0 0.3 2.4 1 1 1 2 2 2 0 Cortexin of kidney zf-RVT PF13966.1 EAU88018.2 - 0.0083 16.4 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RVT_1 PF00078.22 EAU88018.2 - 0.034 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 EAU88020.1 - 0.0019 18.4 2.0 0.0019 18.4 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU88020.1 - 0.01 16.0 5.1 0.017 15.4 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU88020.1 - 0.66 10.3 4.9 0.55 10.6 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.10 EAU88024.1 - 3.8 7.3 7.3 15 5.4 5.1 2.0 1 1 0 1 1 1 0 BED zinc finger LTXXQ PF07813.7 EAU88026.1 - 0.019 15.4 1.8 5.6 7.4 0.1 2.6 2 0 0 2 2 2 0 LTXXQ motif family protein Phasin PF05597.6 EAU88026.1 - 0.046 13.4 1.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Asp_protease_2 PF13650.1 EAU88027.2 - 0.003 18.0 0.0 0.016 15.6 0.0 2.1 1 1 1 2 2 2 1 Aspartyl protease CD99L2 PF12301.3 EAU88029.1 - 0.0051 16.5 1.0 0.0076 15.9 0.7 1.2 1 0 0 1 1 1 1 CD99 antigen like protein 2 Helicase_C PF00271.26 EAU88034.2 - 5.5e-12 45.3 0.0 1.4e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU88034.2 - 5.2e-09 35.8 0.1 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU88034.2 - 0.0089 15.8 0.0 0.047 13.5 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SCO1-SenC PF02630.9 EAU88034.2 - 0.1 12.2 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC DUF3505 PF12013.3 EAU88034.2 - 0.23 11.7 8.2 3.5 7.9 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-Di19 PF05605.7 EAU88034.2 - 1.6 8.9 11.1 0.049 13.7 2.4 2.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DPBB_1 PF03330.13 EAU88036.2 - 2.4e-05 24.2 0.0 4.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 EAU88037.1 - 5.8e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EAU88037.1 - 0.0088 15.7 0.1 0.027 14.1 0.0 1.8 1 1 1 2 2 2 1 Barwin family DPBB_1 PF03330.13 EAU88038.1 - 1.5e-06 28.1 0.0 2.9e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EAU88038.1 - 0.078 12.6 0.1 0.19 11.3 0.0 1.6 1 1 1 2 2 2 0 Barwin family Dishevelled PF02377.10 EAU88038.1 - 1.1 9.5 4.5 2.3 8.4 3.1 1.5 1 0 0 1 1 1 0 Dishevelled specific domain SOG2 PF10428.4 EAU88039.2 - 0.036 12.7 0.4 0.043 12.4 0.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DPBB_1 PF03330.13 EAU88039.2 - 0.041 13.9 0.0 0.091 12.7 0.0 1.7 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel E1-E2_ATPase PF00122.15 EAU88040.2 - 1e-65 221.0 6.5 1e-65 221.0 4.5 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAU88040.2 - 9.9e-46 155.5 8.3 9.9e-46 155.5 5.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAU88040.2 - 3.5e-32 112.5 0.0 2.2e-31 109.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAU88040.2 - 1.2e-21 75.8 0.2 1.7e-20 72.2 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EAU88040.2 - 5.3e-21 74.3 0.0 1e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAU88040.2 - 1.2e-15 58.1 0.0 3.9e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAU88040.2 - 1.5e-06 28.0 2.2 6e-06 26.0 1.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAU88040.2 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Unstab_antitox PF09720.5 EAU88041.1 - 0.7 9.6 5.2 0.6 9.8 2.5 1.7 2 0 0 2 2 2 0 Putative addiction module component CBP4 PF07960.6 EAU88044.2 - 3.8e-12 45.9 0.1 4.9e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 EAU88044.2 - 0.0018 17.9 0.3 0.0024 17.5 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4574) Mg_chelatase_2 PF13335.1 EAU88044.2 - 0.095 13.1 0.5 0.12 12.7 0.4 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Nuc_sug_transp PF04142.10 EAU88047.2 - 1.8e-08 33.8 2.9 2.7e-08 33.2 2.0 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EAU88047.2 - 3.9e-07 30.1 11.8 7.4e-06 26.0 1.6 3.0 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EAU88047.2 - 3e-06 26.3 3.0 6.4e-06 25.2 2.1 1.5 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EAU88047.2 - 0.00012 22.1 6.7 0.00012 22.1 4.7 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EAU88047.2 - 0.0015 18.1 9.4 0.011 15.4 0.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family SHQ1 PF04925.10 EAU88048.1 - 3.9e-51 173.1 0.1 6.6e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 SHQ1 protein CS PF04969.11 EAU88048.1 - 3.6e-05 24.2 0.0 6.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 EAU88048.1 - 9.5e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Chorismate_bind PF00425.13 EAU88049.2 - 3.7e-87 291.9 0.0 5.7e-87 291.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EAU88049.2 - 1.6e-31 109.1 0.0 2.2e-30 105.4 0.0 2.6 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.15 EAU88050.1 - 1.2e-48 165.1 0.0 2.1e-46 157.8 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S2 AAA PF00004.24 EAU88052.1 - 4.5e-15 56.0 0.0 8.9e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EAU88052.1 - 5.6e-13 48.8 0.0 5.8e-12 45.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EAU88052.1 - 7.7e-10 38.0 0.0 6.9e-07 28.3 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EAU88052.1 - 1.2e-08 34.7 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EAU88052.1 - 2.9e-07 30.7 0.0 1.1e-06 28.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EAU88052.1 - 9.3e-06 24.8 0.0 2.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAU88052.1 - 1.2e-05 24.9 0.0 3.2e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EAU88052.1 - 2.1e-05 24.5 0.1 0.00013 21.9 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.1 EAU88052.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU88052.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAU88052.1 - 0.00042 20.0 0.0 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EAU88052.1 - 0.00087 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EAU88052.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EAU88052.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EAU88052.1 - 0.0016 17.6 0.0 0.036 13.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EAU88052.1 - 0.0037 18.0 0.0 0.0095 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAU88052.1 - 0.0098 15.3 0.0 0.027 13.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EAU88052.1 - 0.015 14.7 0.0 0.49 9.7 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain DNA_pol3_delta PF06144.8 EAU88052.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_18 PF13238.1 EAU88052.1 - 0.03 14.6 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EAU88052.1 - 0.032 13.7 0.0 0.27 10.7 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase DAGK_cat PF00781.19 EAU88052.1 - 0.035 13.5 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain AAA_33 PF13671.1 EAU88052.1 - 0.037 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EAU88052.1 - 0.038 13.4 0.1 0.23 10.9 0.0 2.0 1 1 1 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 EAU88052.1 - 0.04 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EAU88052.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAU88052.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAU88052.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 EAU88052.1 - 0.14 11.3 0.0 4.7 6.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein CAF1A PF12253.3 EAU88053.1 - 8.8e-24 83.4 5.6 8.8e-24 83.4 3.9 2.3 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A DUF387 PF04079.11 EAU88053.1 - 0.023 14.0 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative transcriptional regulators (Ypuh-like) PAP2 PF01569.16 EAU88054.2 - 1e-10 41.4 0.4 1e-10 41.4 0.3 2.5 2 2 1 3 3 3 1 PAP2 superfamily Rpp20 PF12328.3 EAU88055.2 - 0.00014 21.5 0.0 0.00034 20.2 0.0 1.8 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P PI-PLC-X PF00388.14 EAU88059.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MIF PF01187.13 EAU88060.2 - 8e-18 64.5 0.0 9e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) fn1 PF00039.13 EAU88061.2 - 3.2 7.6 6.1 3.2 7.6 0.5 2.8 2 1 1 3 3 3 0 Fibronectin type I domain Amidohydro_1 PF01979.15 EAU88062.2 - 4.6e-15 56.1 0.4 7.7e-10 38.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EAU88062.2 - 1.8e-12 47.8 0.5 2e-05 24.7 0.1 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EAU88062.2 - 5.9e-12 45.2 0.1 1.8e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EAU88062.2 - 2.8e-09 36.6 0.2 1.1e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF1077 PF06417.7 EAU88063.2 - 1.9e-44 149.9 0.1 2.4e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RRM_1 PF00076.17 EAU88064.2 - 7.9e-35 118.3 0.0 4e-19 68.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU88064.2 - 4e-16 58.7 0.0 3.6e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU88064.2 - 1.8e-09 37.3 0.0 0.0017 18.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EAU88064.2 - 0.038 13.5 0.2 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 EAU88064.2 - 0.16 11.7 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Ras PF00071.17 EAU88065.1 - 1.1e-53 180.9 0.0 1.3e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU88065.1 - 9.8e-16 58.3 0.0 1.4e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU88065.1 - 2.9e-07 29.9 0.0 3.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family F-box PF00646.28 EAU88068.2 - 0.0018 17.8 0.2 0.0039 16.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF3287 PF11690.3 EAU88068.2 - 0.018 15.1 5.9 0.02 14.9 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) Cas_Csx9 PF09658.5 EAU88068.2 - 0.046 12.5 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) DUF1059 PF06348.6 EAU88068.2 - 0.084 12.7 0.9 0.77 9.6 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Phosducin PF02114.11 EAU88070.1 - 2.1e-07 29.9 0.0 2.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Phosducin DUF3886 PF13025.1 EAU88070.1 - 0.00058 19.7 0.5 0.0017 18.2 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3886) RS4NT PF08071.7 EAU88072.2 - 0.13 12.0 1.0 1.9 8.3 0.1 2.6 2 0 0 2 2 2 0 RS4NT (NUC023) domain Aminotran_5 PF00266.14 EAU88074.1 - 1.5e-32 112.7 0.0 2.2e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF3603 PF12227.3 EAU88076.2 - 0.034 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Cutinase PF01083.17 EAU88080.1 - 5.9e-43 146.6 0.0 6.9e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EAU88080.1 - 1.9e-07 30.7 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EAU88080.1 - 9.7e-06 25.1 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_9 PF10081.4 EAU88080.1 - 0.0022 16.7 0.0 0.0027 16.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family DUF2974 PF11187.3 EAU88080.1 - 0.0024 17.2 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EAU88080.1 - 0.01 16.0 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.2 EAU88080.1 - 0.018 14.7 0.4 0.023 14.4 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EAU88080.1 - 0.068 12.6 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase VirJ PF06057.6 EAU88080.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EAU88080.1 - 0.16 11.3 0.1 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TRAPPC10 PF12584.3 EAU88081.2 - 1.4e-35 121.9 0.0 2.7e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 SNAP PF14938.1 EAU88081.2 - 0.21 10.7 0.3 0.77 8.8 0.0 1.9 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP DEAD PF00270.24 EAU88082.1 - 4.1e-46 156.5 0.0 7.2e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU88082.1 - 6.7e-27 93.1 0.0 1.4e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU88082.1 - 0.00011 22.1 0.0 0.00039 20.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU88082.1 - 0.022 14.8 0.0 0.065 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Cellulase PF00150.13 EAU88084.2 - 1.1e-17 64.1 0.2 2.1e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TBP PF00352.16 EAU88086.1 - 1.5e-68 226.1 0.3 3.7e-34 115.9 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TFIIA PF03153.8 EAU88086.1 - 0.033 14.1 15.7 0.037 13.9 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EAU88086.1 - 3 5.9 23.8 3.8 5.6 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dynamin_M PF01031.15 EAU88087.1 - 5e-103 343.9 0.0 1.7e-102 342.1 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EAU88087.1 - 1.5e-55 187.5 0.0 2.7e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EAU88087.1 - 8.9e-28 96.0 4.4 1.7e-27 95.1 3.1 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAU88087.1 - 0.0022 17.9 1.5 0.024 14.5 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.3 EAU88087.1 - 0.0096 15.6 0.7 0.019 14.7 0.5 1.4 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit Miro PF08477.8 EAU88087.1 - 0.098 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Glyco_hydro_88 PF07470.8 EAU88088.1 - 1.3e-26 93.4 0.0 1.8e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 GlcNAc_2-epim PF07221.6 EAU88088.1 - 0.035 13.1 0.2 2.3 7.1 0.0 2.6 1 1 2 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) DUF1680 PF07944.7 EAU88088.1 - 0.13 10.5 0.1 1 7.5 0.0 2.0 1 1 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) NTF2 PF02136.15 EAU88089.1 - 4.5e-36 123.8 0.0 5e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Helicase_C PF00271.26 EAU88091.2 - 1.7e-07 31.0 0.1 2.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Fer2_BFD PF04324.10 EAU88091.2 - 0.16 12.0 0.5 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Linker_histone PF00538.14 EAU88093.2 - 0.00011 22.2 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family SAP PF02037.22 EAU88094.2 - 6.4e-07 28.7 0.7 3.3e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 SAP domain DUF329 PF03884.9 EAU88094.2 - 0.12 11.9 0.9 4.4 6.9 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-RING_3 PF14369.1 EAU88094.2 - 0.28 11.2 2.1 0.53 10.3 0.1 2.2 2 0 0 2 2 2 0 zinc-finger zf-H2C2_2 PF13465.1 EAU88094.2 - 8.6 6.8 9.0 35 4.9 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double domain DUF59 PF01883.14 EAU88096.2 - 3.6e-11 42.8 0.1 9e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF59 Cullin_binding PF03556.10 EAU88097.2 - 5.5e-26 90.9 2.6 9.7e-26 90.2 1.8 1.4 1 0 0 1 1 1 1 Cullin binding SOBP PF15279.1 EAU88097.2 - 9 6.5 18.5 17 5.6 11.7 1.9 2 0 0 2 2 2 0 Sine oculis-binding protein P5CR_dimer PF14748.1 EAU88098.1 - 2e-39 133.9 1.6 3.7e-39 133.0 1.1 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EAU88098.1 - 7.2e-12 45.5 0.1 3.2e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent DUF2370 PF10176.4 EAU88100.2 - 0.43 9.8 3.2 0.71 9.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) PAP2 PF01569.16 EAU88101.2 - 5.8e-17 61.5 3.5 5.8e-17 61.5 2.4 2.0 3 0 0 3 3 3 1 PAP2 superfamily PAP2_C PF14360.1 EAU88101.2 - 0.00089 19.4 2.8 0.003 17.8 0.4 2.5 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.16 EAU88102.1 - 8.1e-20 70.8 5.6 8.1e-20 70.8 3.9 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EAU88102.1 - 0.014 15.6 1.1 0.014 15.6 0.8 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal CCSMST1 PF15013.1 EAU88102.1 - 0.16 11.9 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 CCSMST1 family Spc24 PF08286.6 EAU88103.1 - 4.6e-12 45.6 0.1 6.1e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Cluap1 PF10234.4 EAU88103.1 - 0.036 13.2 6.1 0.15 11.2 1.4 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 Reo_sigmaC PF04582.7 EAU88103.1 - 0.18 10.9 0.5 0.23 10.6 0.3 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 EAU88103.1 - 0.18 11.3 5.9 2.8 7.5 1.6 2.0 1 1 1 2 2 2 0 IncA protein TBPIP PF07106.8 EAU88103.1 - 0.57 9.7 7.2 0.37 10.3 1.9 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EAU88103.1 - 2.7 6.9 5.4 3.5 6.5 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Ferritin PF00210.19 EAU88103.1 - 2.8 7.7 7.1 0.64 9.7 1.4 2.3 2 1 0 2 2 2 0 Ferritin-like domain Phage_lysis PF03245.8 EAU88103.1 - 8.3 6.4 7.9 3.3 7.7 2.2 2.2 1 1 0 2 2 2 0 Bacteriophage Rz lysis protein DPBB_1 PF03330.13 EAU88104.2 - 1.7e-05 24.6 0.0 3.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EAU88104.2 - 0.015 14.9 0.0 0.031 13.9 0.0 1.5 1 1 0 1 1 1 0 Barwin family Mucin PF01456.12 EAU88104.2 - 0.59 9.8 29.9 1 9.1 20.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Pol_alpha_B_N PF08418.5 EAU88104.2 - 0.62 9.5 5.5 0.9 9.0 3.8 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DAGK_cat PF00781.19 EAU88106.1 - 7.9e-15 54.4 0.1 4.9e-14 51.8 0.1 2.0 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain FH2 PF02181.18 EAU88107.2 - 9.3e-70 235.3 4.9 9.3e-70 235.3 3.4 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_GBD PF06371.8 EAU88107.2 - 1.3e-36 125.7 3.9 1.5e-36 125.5 0.2 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EAU88107.2 - 1.4e-32 112.6 3.2 2.7e-32 111.7 0.0 2.7 2 1 1 3 3 3 1 Diaphanous FH3 Domain TPR_MLP1_2 PF07926.7 EAU88107.2 - 0.00023 20.8 7.3 0.28 10.9 0.0 3.4 2 2 0 2 2 2 2 TPR/MLP1/MLP2-like protein Myosin_head PF00063.16 EAU88108.2 - 5.7e-243 807.9 0.0 9.7e-243 807.2 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EAU88108.2 - 4.4e-34 116.5 2.3 4.4e-34 116.5 1.6 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EAU88108.2 - 5.7e-12 44.1 32.4 0.016 14.8 0.2 7.2 6 0 0 6 6 6 6 IQ calmodulin-binding motif Myosin_N PF02736.14 EAU88108.2 - 0.016 14.8 3.7 0.051 13.2 2.5 1.9 1 1 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EAU88108.2 - 0.024 14.7 5.1 0.026 14.6 0.0 3.1 2 1 1 3 3 3 0 AAA domain APG6 PF04111.7 EAU88108.2 - 0.28 10.1 18.8 0.66 8.9 13.0 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_17 PF13207.1 EAU88108.2 - 0.59 10.9 2.4 2.2 9.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain Fib_alpha PF08702.5 EAU88108.2 - 1.1 9.3 17.9 0.65 10.1 9.9 2.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Phlebovirus_NSM PF07246.6 EAU88108.2 - 3.8 6.5 12.5 8.2 5.4 8.7 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M zf-AN1 PF01428.11 EAU88109.2 - 2.2e-17 62.6 23.0 3.3e-09 36.4 6.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Snf7 PF03357.16 EAU88110.1 - 1.9e-41 141.2 21.3 3.6e-41 140.3 13.9 1.8 2 0 0 2 2 2 1 Snf7 Cullin PF00888.17 EAU88110.1 - 0.032 12.7 0.7 0.057 11.9 0.5 1.3 1 0 0 1 1 1 0 Cullin family TPR_MLP1_2 PF07926.7 EAU88110.1 - 0.21 11.3 10.0 0.4 10.4 7.0 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein YlqD PF11068.3 EAU88110.1 - 0.29 11.1 14.1 1.2 9.2 6.9 2.1 1 1 1 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 EAU88110.1 - 2.1 6.0 8.0 3.9 5.2 5.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 EAU88110.1 - 6.4 6.6 11.2 0.53 10.1 3.1 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 COG4 PF08318.7 EAU88111.1 - 1.2e-54 185.3 0.0 1.7e-54 184.8 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein Glyco_hydro_3 PF00933.16 EAU88112.2 - 1e-76 257.8 0.0 1.6e-76 257.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EAU88112.2 - 5.7e-66 222.2 0.1 8.5e-66 221.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EAU88112.2 - 6.5e-19 67.6 0.0 2.8e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EAU88112.2 - 3.9e-13 49.2 0.0 6.8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.4 EAU88112.2 - 0.0098 14.6 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF2340 PF10209.4 EAU88113.1 - 5.4e-48 162.1 2.3 6.2e-48 161.9 1.6 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DnaJ PF00226.26 EAU88114.1 - 1.4e-23 82.4 0.7 1.4e-23 82.4 0.5 1.7 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 EAU88114.1 - 1.4e-21 76.1 4.1 4.5e-18 64.9 0.0 3.0 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EAU88114.1 - 3.9e-15 55.6 18.1 6.2e-15 55.0 12.6 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EAU88114.1 - 0.24 11.1 10.9 1.8 8.2 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family CN_hydrolase PF00795.17 EAU88115.2 - 4.1e-32 111.0 0.0 5e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PALP PF00291.20 EAU88116.2 - 2.2e-59 201.2 0.0 2.9e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YjeF_N PF03853.10 EAU88116.2 - 0.037 13.6 0.2 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus AlaDh_PNT_C PF01262.16 EAU88116.2 - 0.049 13.2 0.2 0.094 12.2 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PrpR_N PF06506.6 EAU88116.2 - 0.096 12.0 0.1 0.28 10.5 0.1 1.7 2 0 0 2 2 2 0 Propionate catabolism activator Glyco_tran_WecB PF03808.8 EAU88116.2 - 0.15 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family CitT PF12431.3 EAU88116.2 - 0.17 11.9 0.1 0.48 10.5 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Borrelia_orfA PF02414.10 EAU88116.2 - 0.2 10.6 0.1 0.3 10.1 0.1 1.1 1 0 0 1 1 1 0 Borrelia ORF-A DUF2346 PF09803.4 EAU88117.1 - 3e-10 39.8 0.3 5.6e-10 38.9 0.2 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) Luteo_PO PF04662.8 EAU88117.1 - 0.016 14.6 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Luteovirus P0 protein Cwf_Cwc_15 PF04889.7 EAU88117.1 - 0.056 13.1 3.6 0.067 12.8 2.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1192 PF06698.6 EAU88117.1 - 0.24 11.2 6.2 0.32 10.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) EF-1_beta_acid PF10587.4 EAU88117.1 - 1.4 9.1 9.0 0.71 10.0 3.8 2.1 1 1 1 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Pyridoxal_deC PF00282.14 EAU88118.1 - 3.6e-59 200.1 0.0 5.4e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Otopetrin PF03189.8 EAU88119.1 - 0.15 10.9 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Otopetrin FdhE PF04216.7 EAU88119.1 - 3.6 7.2 6.4 3.9 7.1 0.3 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation DNA_pol_E_B PF04042.11 EAU88120.2 - 1.2e-32 112.8 0.0 9.1e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B EAP30 PF04157.11 EAU88121.1 - 2.1e-47 161.1 0.0 2.4e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Viral_cys_rich PF08008.7 EAU88121.1 - 0.05 13.1 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral cysteine rich UBA PF00627.26 EAU88121.1 - 0.11 12.3 0.2 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 UBA/TS-N domain PBP PF01161.15 EAU88122.1 - 1.3e-16 60.7 0.0 1.8e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Hid1 PF12722.2 EAU88123.2 - 5.4e-131 438.0 0.0 3.1e-130 435.5 0.0 2.0 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EAU88123.2 - 7.5e-52 176.3 0.0 9.8e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DAZAP2 PF11029.3 EAU88123.2 - 0.12 12.8 0.1 0.12 12.8 0.1 2.7 4 0 0 4 4 4 0 DAZ associated protein 2 (DAZAP2) PBP PF01161.15 EAU88124.1 - 2.7e-14 53.2 0.0 4.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein G-patch PF01585.18 EAU88125.2 - 1.8e-13 50.0 1.6 1.8e-13 50.0 1.1 1.9 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.17 EAU88125.2 - 1.4e-06 27.8 1.0 0.0029 17.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EAU88125.2 - 1.2e-05 25.0 1.7 1.2e-05 25.0 1.2 2.8 2 1 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EAU88125.2 - 6.4e-05 22.7 0.4 0.0041 16.9 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU88125.2 - 8.5e-05 22.4 0.1 0.036 14.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 EAU88125.2 - 0.014 14.6 0.3 0.014 14.6 0.2 1.9 2 0 0 2 2 2 0 RED-like protein N-terminal region NDUF_B4 PF07225.7 EAU88126.1 - 0.00057 19.6 0.1 0.00066 19.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) COQ7 PF03232.8 EAU88127.1 - 9.4e-69 230.2 0.4 1.1e-68 230.0 0.3 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin_2 PF13668.1 EAU88127.1 - 0.11 12.3 0.1 7.5 6.5 0.0 2.3 1 1 1 2 2 2 0 Ferritin-like domain AOX PF01786.12 EAU88127.1 - 0.52 9.6 2.5 9 5.6 1.8 2.3 1 1 0 1 1 1 0 Alternative oxidase WD40 PF00400.27 EAU88129.2 - 1.5e-63 208.5 25.4 1.6e-10 40.4 0.3 8.1 7 2 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EAU88129.2 - 4.1e-15 55.2 1.0 8e-15 54.2 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU88129.2 - 9.5e-12 44.2 0.2 1.9e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EAU88129.2 - 1e-09 37.1 12.5 0.2 9.7 0.0 6.1 2 2 4 6 6 6 6 Nucleoporin Nup120/160 Pkinase PF00069.20 EAU88130.2 - 7.2e-63 212.1 0.0 8.4e-63 211.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88130.2 - 3.8e-25 88.4 0.0 4.9e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU88130.2 - 1.6e-05 24.0 0.0 3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU88130.2 - 0.00042 20.1 0.1 0.031 14.0 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU88130.2 - 0.0034 16.9 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Gastrin PF00918.12 EAU88131.2 - 0.072 13.9 1.2 0.15 12.8 0.8 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Lactamase_B_2 PF12706.2 EAU88134.1 - 5.1e-18 65.3 0.0 9e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAU88134.1 - 8.5e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 EAU88134.1 - 0.0033 16.4 0.0 0.016 14.1 0.0 2.0 3 0 0 3 3 3 1 cAMP phosphodiesterases class-II Phageshock_PspG PF09583.5 EAU88134.1 - 0.44 10.6 7.3 0.85 9.7 5.1 1.4 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) Linker_histone PF00538.14 EAU88138.2 - 2.3e-13 50.0 0.0 4.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family AMP-binding PF00501.23 EAU88139.1 - 3.3e-18 65.2 0.0 5.9e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.14 EAU88141.2 - 2.1e-14 53.3 0.0 5.8e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family ABC2_membrane_3 PF12698.2 EAU88141.2 - 0.6 9.0 1.6 0.78 8.7 1.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Telomere_reg-2 PF10193.4 EAU88142.1 - 2.3e-25 89.0 0.0 6.6e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein DAP_epimerase PF01678.14 EAU88142.1 - 0.26 11.1 0.1 0.5 10.2 0.0 1.4 1 0 0 1 1 1 0 Diaminopimelate epimerase 2Fe-2S_thioredx PF01257.14 EAU88143.2 - 7.3e-60 200.7 0.1 9.4e-60 200.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.16 EAU88144.1 - 8.1e-50 169.4 0.1 1.4e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Glyco_hydro_63 PF03200.11 EAU88146.2 - 3.2e-210 700.0 0.1 2.4e-208 693.8 0.0 2.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EAU88146.2 - 0.0016 17.2 0.4 0.0053 15.4 0.0 1.8 2 0 0 2 2 2 1 Trehalase GDE_C PF06202.9 EAU88146.2 - 0.002 16.9 0.0 0.0033 16.2 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Band_7 PF01145.20 EAU88147.1 - 1.4e-05 25.1 0.0 1.4e-05 25.1 0.0 3.1 3 1 1 4 4 4 1 SPFH domain / Band 7 family Atg8 PF02991.11 EAU88148.1 - 4.1e-52 174.4 0.2 4.9e-52 174.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EAU88148.1 - 3.3e-07 30.4 0.0 4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Rad51 PF08423.6 EAU88150.2 - 2.1e-22 79.2 0.0 3.4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EAU88150.2 - 2.3e-09 36.9 0.0 5.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EAU88150.2 - 0.00013 21.1 0.3 0.00059 19.0 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 EAU88150.2 - 0.00046 19.3 0.1 0.0017 17.5 0.1 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EAU88150.2 - 0.0058 15.5 0.4 0.011 14.6 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EAU88150.2 - 0.045 13.8 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Pept_tRNA_hydro PF01195.14 EAU88150.2 - 0.14 11.5 0.0 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase TPR_11 PF13414.1 EAU88152.1 - 1.3e-08 34.3 3.7 2.3e-05 23.9 0.9 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAU88152.1 - 0.00059 19.5 5.1 0.029 14.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU88152.1 - 0.0014 18.1 0.8 0.35 10.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU88152.1 - 0.014 15.1 3.8 0.21 11.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Rbsn PF11464.3 EAU88152.1 - 0.06 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Rabenosyn Rab binding domain TPR_16 PF13432.1 EAU88152.1 - 0.071 13.8 8.0 4.8 7.9 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EAU88152.1 - 0.16 11.8 1.4 6.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU88152.1 - 0.21 11.5 4.7 0.35 10.8 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat NYN PF01936.13 EAU88153.1 - 1.5e-05 25.2 0.0 3.7e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 NYN domain DUF605 PF04652.11 EAU88153.1 - 4.5 6.5 15.1 6.3 6.0 10.5 1.2 1 0 0 1 1 1 0 Vta1 like CHCH PF06747.8 EAU88154.1 - 2.3e-05 24.1 0.8 2.9e-05 23.8 0.5 1.1 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EAU88154.1 - 0.02 14.6 0.2 0.03 14.1 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like UQ_con PF00179.21 EAU88155.2 - 1e-22 80.1 0.0 1.5e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rubredoxin PF00301.15 EAU88155.2 - 0.033 14.0 0.3 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin RWD PF05773.17 EAU88155.2 - 0.035 14.0 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 RWD domain zf-Sec23_Sec24 PF04810.10 EAU88155.2 - 0.052 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EAU88155.2 - 0.52 9.4 5.3 0.081 12.0 0.4 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others PRP21_like_P PF12230.3 EAU88157.1 - 1.1e-56 191.9 14.8 1.1e-56 191.9 10.3 2.3 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EAU88157.1 - 7.5e-33 111.9 0.3 9.1e-16 57.2 0.1 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 EAU88157.1 - 5.5e-08 32.0 0.0 1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAU88157.1 - 0.00058 19.5 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAU88157.1 - 0.11 12.6 1.1 0.41 10.8 0.0 2.4 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain FLO_LFY PF01698.11 EAU88157.1 - 0.72 8.6 19.1 0.053 12.3 7.4 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein L31 PF09784.4 EAU88158.1 - 9.7e-38 128.3 0.2 1.1e-37 128.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.1 EAU88159.1 - 2.6e-102 341.2 4.1 3.2e-102 340.9 2.9 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DinB_2 PF12867.2 EAU88159.1 - 0.11 12.8 0.2 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 DinB superfamily RNase_T PF00929.19 EAU88160.2 - 7.7e-16 58.8 0.0 2.2e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Exonuclease Ndc80_HEC PF03801.8 EAU88162.2 - 8e-36 122.8 0.2 2.2e-35 121.4 0.1 1.8 1 1 0 1 1 1 1 HEC/Ndc80p family EzrA PF06160.7 EAU88162.2 - 0.00026 19.3 0.7 0.00026 19.3 0.5 2.9 3 0 0 3 3 3 2 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 EAU88162.2 - 0.0058 16.7 26.8 0.057 13.5 1.6 3.6 3 1 1 4 4 4 3 Fibrinogen alpha/beta chain family Uds1 PF15456.1 EAU88162.2 - 0.012 15.6 5.8 0.012 15.6 4.0 3.6 2 2 0 3 3 3 0 Up-regulated During Septation Filament PF00038.16 EAU88162.2 - 0.92 8.9 33.0 0.42 10.0 4.8 3.7 1 1 0 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 EAU88162.2 - 1.6 7.8 9.8 0.96 8.5 2.0 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EAU88162.2 - 3.9 7.2 22.0 0.64 9.7 2.2 3.5 2 2 2 4 4 4 0 Laminin Domain II Spc7 PF08317.6 EAU88162.2 - 4.7 5.7 32.7 0.92 8.1 9.4 3.3 2 2 1 3 3 3 0 Spc7 kinetochore protein COG5 PF10392.4 EAU88162.2 - 5.7 6.9 15.5 2 8.4 5.6 3.5 2 2 1 3 3 3 0 Golgi transport complex subunit 5 TBPIP PF07106.8 EAU88162.2 - 7.8 6.0 31.7 1.7 8.1 0.8 4.3 2 2 1 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mog1 PF04603.7 EAU88163.2 - 3.9e-31 107.8 0.1 5.2e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein CENP-Q PF13094.1 EAU88164.2 - 0.0095 15.9 16.6 0.052 13.5 5.9 3.2 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2383 PF09537.5 EAU88164.2 - 0.023 14.9 0.5 0.096 12.9 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF972 PF06156.8 EAU88164.2 - 0.046 14.0 12.3 0.15 12.4 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 EAU88164.2 - 0.089 12.5 0.5 0.089 12.5 0.4 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper LMSTEN PF07988.7 EAU88164.2 - 0.1 11.9 1.6 0.25 10.6 1.1 1.7 1 0 0 1 1 1 0 LMSTEN motif CCDC-167 PF15188.1 EAU88164.2 - 0.29 11.1 5.8 1.2 9.1 0.5 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 EAU88164.2 - 0.58 9.7 10.1 0.25 10.9 0.4 2.6 3 0 0 3 3 3 0 IncA protein DivIVA PF05103.8 EAU88164.2 - 1.4 8.9 20.2 3.4 7.7 5.6 2.8 3 0 0 3 3 3 0 DivIVA protein DUF904 PF06005.7 EAU88164.2 - 2.6 8.3 13.8 3.8 7.8 0.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DUF342 PF03961.8 EAU88164.2 - 2.9 6.2 7.3 8 4.7 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TMF_TATA_bd PF12325.3 EAU88164.2 - 3.7 7.2 12.6 1 9.0 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spectrin PF00435.16 EAU88164.2 - 4.6 7.5 11.3 3.3 8.0 2.3 2.8 3 0 0 3 3 3 0 Spectrin repeat ADIP PF11559.3 EAU88164.2 - 6 6.7 17.2 2.5 7.9 1.5 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.13 EAU88164.2 - 8 6.5 8.6 6.1 6.8 0.8 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family HECT PF00632.20 EAU88165.2 - 4e-90 302.1 0.0 5.6e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EAU88165.2 - 5.6e-34 115.6 22.1 7.5e-11 41.6 5.1 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EAU88165.2 - 6.3e-16 57.9 0.2 1.7e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.8 EAU88165.2 - 0.95 9.2 19.7 1.6 8.5 13.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_MCEL PF03291.11 EAU88166.2 - 5.1e-85 285.2 0.0 7e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 EAU88166.2 - 2.1e-09 37.1 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU88166.2 - 5.7e-08 33.1 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU88166.2 - 1.6e-07 31.8 0.0 3.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU88166.2 - 8.7e-07 28.7 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU88166.2 - 1.1e-06 29.0 0.0 2.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU88166.2 - 1.2e-05 25.5 0.1 3.6e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU88166.2 - 2.2e-05 23.9 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EAU88166.2 - 0.0006 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EAU88166.2 - 0.0009 18.2 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Peptidase_M1 PF01433.15 EAU88167.2 - 1.2e-116 390.0 0.0 1.1e-70 238.6 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EAU88167.2 - 9.8e-67 225.4 0.1 1.3e-66 225.0 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EAU88167.2 - 1.5e-16 60.6 0.5 1.3e-15 57.5 0.1 2.4 2 0 0 2 2 2 1 Peptidase MA superfamily BLOC1_2 PF10046.4 EAU88167.2 - 0.01 15.9 0.4 0.022 14.8 0.3 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IcmL PF11393.3 EAU88167.2 - 0.02 14.8 0.5 0.045 13.6 0.3 1.5 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein NYN PF01936.13 EAU88168.2 - 1.2e-05 25.6 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 NYN domain NYN PF01936.13 EAU88169.2 - 4.3e-05 23.8 0.0 7.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NYN domain NYN PF01936.13 EAU88170.1 - 6.9e-11 42.6 0.0 1.3e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 NYN domain NYN PF01936.13 EAU88171.1 - 1e-11 45.3 0.0 1.5e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 NYN domain PAM2 PF07145.10 EAU88171.1 - 0.042 13.3 0.3 0.11 12.1 0.2 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region NYN PF01936.13 EAU88172.1 - 7.6e-05 23.0 0.1 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 NYN domain BTV_NS2 PF04514.7 EAU88177.1 - 0.13 11.0 8.0 0.036 12.9 0.7 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 PPP4R2 PF09184.6 EAU88177.1 - 3.7 7.0 15.4 0.19 11.2 3.3 2.5 2 0 0 2 2 2 0 PPP4R2 SDA1 PF05285.7 EAU88177.1 - 5 6.3 19.6 2 7.6 1.2 2.2 2 0 0 2 2 2 0 SDA1 Cwf_Cwc_15 PF04889.7 EAU88177.1 - 5.3 6.6 21.9 0.31 10.7 5.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pyr_redox_2 PF07992.9 EAU88178.1 - 1.9e-36 125.8 9.0 2.4e-35 122.2 6.2 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EAU88178.1 - 1.5e-33 115.1 0.2 5.5e-33 113.2 0.1 2.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EAU88178.1 - 1.3e-21 76.8 3.5 1.4e-18 67.0 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU88178.1 - 3.8e-09 36.9 0.1 0.0016 18.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU88178.1 - 5.4e-07 28.4 1.6 0.0019 16.7 0.0 2.5 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 EAU88178.1 - 1.1e-06 28.0 0.2 2.3e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EAU88178.1 - 3.2e-05 22.9 3.1 0.0043 15.9 1.2 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 EAU88178.1 - 6.7e-05 21.9 0.0 0.00028 19.9 0.0 1.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EAU88178.1 - 0.00016 20.7 11.5 0.0024 16.8 1.2 2.9 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU88178.1 - 0.00027 20.8 1.0 0.00081 19.3 0.7 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAU88178.1 - 0.0019 17.9 1.1 0.064 13.0 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EAU88178.1 - 0.034 13.3 0.9 0.6 9.2 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EAU88178.1 - 0.052 13.1 0.1 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EAU88178.1 - 0.053 13.7 0.1 7.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EAU88178.1 - 0.18 11.4 0.1 0.18 11.4 0.0 2.5 3 0 0 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EAU88178.1 - 0.7 8.6 8.8 0.08 11.7 0.2 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A PIN_4 PF13638.1 EAU88181.2 - 8.4e-23 80.9 0.2 8.4e-23 80.9 0.1 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.4 EAU88181.2 - 8.7e-13 48.1 0.0 1.3e-11 44.2 0.0 2.6 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Cytochrom_B561 PF03188.11 EAU88182.2 - 1.4e-08 34.6 1.5 2.3e-08 33.9 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EAU88182.2 - 0.00045 19.7 0.6 0.0031 17.0 0.4 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) DOMON PF03351.12 EAU88182.2 - 0.0072 16.2 2.0 0.0092 15.9 0.0 2.0 2 0 0 2 2 2 1 DOMON domain DUF912 PF06024.7 EAU88182.2 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NDK PF00334.14 EAU88183.1 - 2.2e-54 182.8 0.0 2.5e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 EAU88183.1 - 0.05 13.3 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ UCR_14kD PF02271.11 EAU88184.1 - 3.9e-39 132.6 0.5 4.4e-39 132.4 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Transketolase_N PF00456.16 EAU88185.1 - 1.5e-147 490.7 0.0 2e-147 490.3 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EAU88185.1 - 2e-42 144.6 0.0 4.1e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EAU88185.1 - 1.4e-13 50.8 0.0 3.6e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EAU88185.1 - 0.00017 20.6 0.0 0.00035 19.5 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EAU88185.1 - 0.0037 16.0 0.0 0.0056 15.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component adh_short_C2 PF13561.1 EAU88186.2 - 2e-25 89.9 0.0 2.5e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU88186.2 - 8.7e-25 87.5 0.3 1.1e-24 87.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU88186.2 - 3.6e-14 52.8 0.2 5e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EAU88186.2 - 0.011 14.4 0.0 0.017 13.8 0.0 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SnoaL_2 PF12680.2 EAU88187.2 - 0.0025 18.1 0.0 0.0038 17.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.4 EAU88187.2 - 0.0076 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) WD40 PF00400.27 EAU88188.1 - 7.7e-39 130.2 13.0 8.5e-12 44.4 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Sulfate_transp PF00916.15 EAU88189.2 - 1.3e-76 257.3 5.1 2.8e-76 256.1 3.5 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EAU88189.2 - 1.3e-32 111.2 4.2 1.3e-32 111.2 2.9 4.2 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EAU88189.2 - 3.7e-09 36.0 0.0 1e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 EAU88189.2 - 0.0024 17.8 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 STAS domain Transcrip_reg PF01709.15 EAU88190.1 - 5.1e-61 205.7 0.5 5.9e-61 205.5 0.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator NYN PF01936.13 EAU88192.2 - 8e-25 87.8 0.0 1.7e-24 86.7 0.0 1.5 2 0 0 2 2 2 1 NYN domain Biotin_lipoyl PF00364.17 EAU88193.2 - 1.3e-09 37.5 0.3 1.9e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EAU88193.2 - 0.0012 18.4 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like QRPTase_N PF02749.11 EAU88193.2 - 0.036 13.8 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Rad1 PF02144.11 EAU88194.2 - 6.6e-74 248.1 0.0 1.9e-70 236.7 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Biotin_lipoyl PF00364.17 EAU88195.1 - 5.1e-20 70.8 0.4 9.8e-20 69.9 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EAU88195.1 - 1.3e-08 34.3 0.5 6e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EAU88195.1 - 0.00015 21.3 0.1 0.00059 19.4 0.0 2.0 2 1 0 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 EAU88195.1 - 0.15 11.1 0.0 4.6 6.3 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Sterol-sensing PF12349.3 EAU88196.2 - 4.5e-18 65.1 1.5 1.3e-17 63.6 1.0 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EAU88196.2 - 2.1e-05 22.6 0.3 3e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 Patched family HIRA_B PF09453.5 EAU88196.2 - 0.049 13.1 0.1 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 HIRA B motif WD40 PF00400.27 EAU88196.2 - 0.096 12.6 2.5 18 5.4 0.4 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Hat1_N PF10394.4 EAU88198.2 - 1.4e-40 139.0 0.1 2.9e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EAU88198.2 - 0.027 14.5 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Leuk-A4-hydro_C PF09127.6 EAU88198.2 - 0.073 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Mac PF12464.3 EAU88198.2 - 0.086 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase CoA_trans PF01144.18 EAU88199.2 - 1.2e-99 331.9 0.9 1.7e-58 197.3 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EAU88199.2 - 0.00041 20.0 0.1 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain Aldedh PF00171.17 EAU88201.1 - 4.8e-126 420.7 0.0 6e-126 420.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SMI1_KNR4 PF09346.5 EAU88202.2 - 1.3e-24 86.6 0.0 2.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Oxidored_FMN PF00724.15 EAU88203.1 - 2.4e-19 69.5 0.0 1.3e-11 44.0 0.0 2.3 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family APH PF01636.18 EAU88204.1 - 1.2e-05 25.1 0.4 8.3e-05 22.4 0.3 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family AAA PF00004.24 EAU88205.1 - 1.4e-44 151.4 0.0 3.3e-44 150.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAU88205.1 - 6.8e-09 35.5 0.1 2.2e-08 33.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAU88205.1 - 4.9e-07 29.9 0.0 1.7e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EAU88205.1 - 1.1e-06 28.6 0.2 3.3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EAU88205.1 - 4.9e-06 25.6 0.0 9.7e-06 24.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EAU88205.1 - 1.2e-05 25.5 2.6 0.00062 19.9 0.2 3.1 2 1 1 3 3 2 1 AAA domain AAA_14 PF13173.1 EAU88205.1 - 4.3e-05 23.4 0.0 0.00068 19.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EAU88205.1 - 6.6e-05 22.9 0.0 0.00037 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU88205.1 - 0.00016 21.3 0.1 0.00041 20.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EAU88205.1 - 0.00046 20.9 0.1 0.0038 18.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAU88205.1 - 0.00055 19.0 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EAU88205.1 - 0.00071 19.8 0.0 0.013 15.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAU88205.1 - 0.00079 18.8 4.3 0.013 14.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 EAU88205.1 - 0.0013 18.9 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 EAU88205.1 - 0.0022 17.6 0.1 0.017 14.7 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EAU88205.1 - 0.0031 16.2 0.0 0.0061 15.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EAU88205.1 - 0.0033 16.8 0.5 0.0096 15.3 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.10 EAU88205.1 - 0.0037 16.9 0.1 0.012 15.3 0.1 2.0 1 1 0 1 1 1 1 NTPase NACHT PF05729.7 EAU88205.1 - 0.0047 16.5 0.1 0.052 13.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EAU88205.1 - 0.0059 16.4 0.0 0.017 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EAU88205.1 - 0.0064 15.6 0.1 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAU88205.1 - 0.0075 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EAU88205.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EAU88205.1 - 0.012 15.2 0.0 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EAU88205.1 - 0.012 15.2 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAU88205.1 - 0.02 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EAU88205.1 - 0.026 14.2 0.3 0.23 11.1 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 EAU88205.1 - 0.028 13.2 0.1 0.064 12.0 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.21 EAU88205.1 - 0.037 13.5 0.1 1.1 8.7 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_23 PF13476.1 EAU88205.1 - 0.042 14.1 0.1 0.71 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EAU88205.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 EAU88205.1 - 0.071 12.2 0.8 0.38 9.8 0.0 2.4 3 0 0 3 3 3 0 KaiC ABC_tran PF00005.22 EAU88205.1 - 0.073 13.3 0.2 0.43 10.8 0.0 2.4 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.12 EAU88205.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 EAU88205.1 - 0.13 11.6 0.3 0.9 8.9 0.1 2.3 1 1 1 2 2 2 0 AAA-like domain RRM_5 PF13893.1 EAU88206.2 - 0.00046 19.9 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU88206.2 - 0.0042 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU88206.2 - 0.13 12.2 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU88207.2 - 0.013 15.4 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EAU88208.2 - 2.2e-29 102.5 69.7 2.2e-29 102.4 20.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1777) SUI1 PF01253.17 EAU88209.2 - 2.4e-30 104.1 0.6 2.9e-30 103.9 0.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF608 PF04685.8 EAU88209.2 - 0.048 12.3 0.0 0.056 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Nop25 PF09805.4 EAU88210.1 - 0.02 14.9 1.8 0.02 14.9 1.3 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) rRNA_processing PF08524.6 EAU88210.1 - 0.14 11.9 13.0 0.11 12.3 2.1 2.5 2 1 0 2 2 2 0 rRNA processing Daxx PF03344.10 EAU88210.1 - 0.58 8.5 6.9 0.67 8.3 4.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF2890 PF11081.3 EAU88210.1 - 1.2 9.2 12.7 1.5 8.7 8.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) TPR_12 PF13424.1 EAU88214.2 - 8.1e-08 32.0 1.3 0.064 13.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAU88214.2 - 0.022 14.4 0.2 10 5.8 0.0 3.3 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 EAU88214.2 - 0.1 12.5 1.3 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PAP2 PF01569.16 EAU88215.2 - 7.3e-28 96.8 1.6 7.3e-28 96.8 1.1 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF3397 PF11877.3 EAU88215.2 - 0.12 12.3 2.9 0.84 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) PPP4R2 PF09184.6 EAU88216.2 - 3.6e-23 82.5 14.3 4.3e-22 78.9 0.0 2.4 2 1 0 2 2 2 1 PPP4R2 RR_TM4-6 PF06459.7 EAU88216.2 - 0.43 10.4 7.1 0.74 9.6 4.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ATP-synt_B PF00430.13 EAU88216.2 - 0.47 10.2 6.0 0.91 9.3 4.1 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Vfa1 PF08432.5 EAU88216.2 - 2 8.4 11.4 4.1 7.3 7.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.6 EAU88216.2 - 6.2 4.8 6.6 9 4.2 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HhH-GPD PF00730.20 EAU88217.1 - 1.3e-18 67.2 0.0 2.3e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EAU88217.1 - 4.1e-09 35.6 0.0 1.1e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EAU88217.1 - 0.0012 18.9 0.7 0.003 17.6 0.5 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.1 EAU88217.1 - 0.1 12.8 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Catalase PF00199.14 EAU88218.2 - 2.4e-164 546.5 0.0 3.8e-164 545.9 0.0 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EAU88218.2 - 4.6e-20 71.2 0.2 9.2e-20 70.2 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EAU88218.2 - 2.1e-11 43.4 0.1 3.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EAU88218.2 - 4.8e-06 25.9 0.0 8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase PhoD PF09423.5 EAU88219.2 - 2.8e-07 29.4 0.0 0.0005 18.7 0.0 2.4 2 0 0 2 2 2 2 PhoD-like phosphatase SPRY PF00622.23 EAU88222.2 - 8.8e-09 35.5 0.0 1.7e-07 31.3 0.0 2.6 3 0 0 3 3 3 1 SPRY domain DNA_pol_phi PF04931.8 EAU88224.2 - 9.9e-66 222.0 26.9 9.9e-66 222.0 18.6 3.3 3 1 0 3 3 3 2 DNA polymerase phi RasGEF_N PF00618.15 EAU88224.2 - 0.031 14.3 0.2 17 5.5 0.0 3.4 3 0 0 3 3 3 0 RasGEF N-terminal motif MutS_V PF00488.16 EAU88225.2 - 5e-83 278.0 0.0 2.3e-82 275.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EAU88225.2 - 2e-38 132.2 1.4 3.7e-38 131.3 0.2 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EAU88225.2 - 8.1e-22 77.3 0.0 1.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EAU88225.2 - 2.8e-10 40.3 0.0 3.3e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 MutS domain II ATP12 PF07542.6 EAU88226.1 - 1.5e-40 137.9 0.0 2.8e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Nt_Gln_amidase PF09764.4 EAU88229.2 - 4.8e-27 94.4 0.1 5.6e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase UQ_con PF00179.21 EAU88233.1 - 1.4e-33 115.2 0.2 1.6e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAU88233.1 - 6.3e-06 25.9 0.0 7.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAU88233.1 - 0.00028 20.7 0.1 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EAU88233.1 - 0.0034 17.0 0.1 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Glycos_transf_1 PF00534.15 EAU88234.1 - 6.8e-23 80.9 0.0 1.5e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EAU88234.1 - 5.1e-11 42.8 0.0 1.4e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EAU88234.1 - 3.3e-07 30.4 0.0 7.5e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TF_Zn_Ribbon PF08271.7 EAU88235.1 - 0.0016 17.7 1.3 0.0033 16.7 0.9 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.14 EAU88235.1 - 0.0037 17.0 0.3 0.025 14.3 0.0 2.4 2 1 1 3 3 3 1 Transcription factor TFIIB repeat CAP_N PF01213.14 EAU88236.1 - 1.1e-71 241.6 28.2 6.3e-69 232.6 19.5 3.2 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EAU88236.1 - 2.1e-56 189.6 7.2 2.7e-56 189.3 5.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EAU88236.1 - 0.00021 20.6 3.7 0.00034 19.9 2.6 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C DUF2360 PF10152.4 EAU88236.1 - 0.014 15.6 5.1 1.6 9.0 1.2 3.1 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Mito_fiss_reg PF05308.6 EAU88236.1 - 1.2 8.4 25.6 0.014 14.8 3.4 3.0 2 1 1 3 3 3 0 Mitochondrial fission regulator RF-1 PF00472.15 EAU88237.1 - 2.1e-26 91.9 4.3 2.1e-26 91.9 3.0 1.7 2 0 0 2 2 2 1 RF-1 domain SCIMP PF15050.1 EAU88237.1 - 1.4 8.8 5.1 4.9 7.0 2.7 2.1 1 1 1 2 2 2 0 SCIMP protein tRNA_int_endo PF01974.12 EAU88239.2 - 8.1e-06 25.5 0.3 2e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Remorin_C PF03763.8 EAU88239.2 - 0.0043 16.5 6.1 0.0062 16.0 2.8 1.9 2 0 0 2 2 2 1 Remorin, C-terminal region tRNA_int_end_N2 PF12928.2 EAU88239.2 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term DUF2360 PF10152.4 EAU88239.2 - 0.94 9.7 5.7 1.5 9.1 3.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Lipase_GDSL_2 PF13472.1 EAU88240.2 - 3e-29 102.4 0.0 3.7e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU88240.2 - 1.5e-25 90.4 0.0 1.9e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.15 EAU88241.1 - 2.8e-13 50.2 0.0 5.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Cpn60_TCP1 PF00118.19 EAU88242.1 - 1.7e-141 472.1 12.2 1.9e-141 472.0 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 EAU88242.1 - 0.0031 16.8 0.2 0.0088 15.2 0.0 1.9 2 1 0 2 2 2 1 Telomere recombination TPR_1 PF00515.23 EAU88243.2 - 2.9e-28 96.2 12.4 1.2e-07 30.9 0.4 7.2 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EAU88243.2 - 3.9e-28 96.9 22.4 1.3e-10 40.7 0.8 7.1 4 2 2 7 7 7 5 TPR repeat TPR_12 PF13424.1 EAU88243.2 - 3.4e-25 87.7 18.0 6e-10 38.9 0.7 5.8 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAU88243.2 - 7.8e-25 84.7 18.5 5.4e-05 22.8 0.5 8.2 9 0 0 9 9 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EAU88243.2 - 4.6e-23 81.1 25.8 1.3e-14 54.0 1.7 5.4 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EAU88243.2 - 5.7e-21 72.9 12.8 0.0049 16.9 0.2 7.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAU88243.2 - 6.7e-21 74.4 27.9 8.2e-05 23.1 0.0 7.5 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EAU88243.2 - 2.9e-19 67.8 12.5 0.00026 21.3 0.1 8.1 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EAU88243.2 - 4.7e-18 65.2 16.6 0.00014 22.1 0.2 7.9 6 3 1 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EAU88243.2 - 2e-17 61.5 2.8 0.012 15.3 0.1 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EAU88243.2 - 1.3e-11 44.1 9.3 0.35 11.4 0.0 7.6 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAU88243.2 - 1.3e-09 37.0 9.7 0.12 12.2 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 EAU88243.2 - 0.00033 20.7 2.1 0.49 10.5 0.1 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAU88243.2 - 0.0026 17.5 11.5 0.0077 16.0 0.5 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAU88243.2 - 0.0038 17.1 7.3 14 5.7 0.1 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 EAU88243.2 - 0.0085 15.9 1.7 0.037 13.8 0.1 3.0 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EAU88243.2 - 0.009 16.6 4.8 21 5.9 0.4 4.2 3 0 0 3 3 3 0 Sel1 repeat TOM20_plant PF06552.7 EAU88243.2 - 0.01 15.4 1.2 19 4.7 0.0 4.0 2 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 PPTA PF01239.17 EAU88243.2 - 0.22 10.9 2.8 18 4.8 0.0 3.8 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.1 EAU88243.2 - 0.79 9.6 10.9 31 4.5 0.1 6.1 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.1 EAU88243.2 - 1.3 8.1 8.7 0.67 9.0 0.2 3.6 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP Kisspeptin PF15152.1 EAU88243.2 - 1.9 9.2 8.5 13 6.5 1.9 3.2 2 0 0 2 2 2 0 Kisspeptin DUF4526 PF15029.1 EAU88245.2 - 0.083 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) PUA PF01472.15 EAU88246.2 - 2.1e-08 33.7 0.2 2.7e-08 33.4 0.1 1.2 1 1 0 1 1 1 1 PUA domain CRM1_C PF08767.6 EAU88247.2 - 8.8e-135 448.7 0.5 8.8e-135 448.7 0.4 3.2 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EAU88247.2 - 2.2e-43 147.7 8.0 4.9e-42 143.3 5.2 3.4 4 1 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EAU88247.2 - 1.2e-12 47.6 0.0 5.3e-12 45.4 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain ADH_zinc_N_2 PF13602.1 EAU88249.1 - 2e-20 73.9 0.0 3.9e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EAU88249.1 - 2.4e-12 46.5 0.0 4e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU88249.1 - 0.0016 18.1 0.0 0.12 12.1 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EAU88249.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Cutinase PF01083.17 EAU88250.1 - 4.7e-43 147.0 0.0 6e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EAU88250.1 - 5.1e-06 26.1 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EAU88250.1 - 7.2e-05 22.3 0.0 9.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_9 PF10081.4 EAU88250.1 - 0.00096 17.9 0.0 0.0011 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta-hydrolase family DUF2974 PF11187.3 EAU88250.1 - 0.0065 15.8 0.0 0.0093 15.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EAU88250.1 - 0.0083 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EAU88250.1 - 0.011 15.4 0.7 0.02 14.6 0.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 EAU88250.1 - 0.062 13.0 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EAU88250.1 - 0.098 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_tran_28_C PF04101.11 EAU88251.1 - 2.3e-30 105.4 0.0 2.6e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EAU88251.1 - 2.8e-06 26.7 0.0 3.3e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_transf_41 PF13844.1 EAU88251.1 - 0.092 10.6 0.0 4.6 5.1 0.0 2.0 1 1 1 2 2 2 0 Glycosyl transferase family 41 Methyltransf_11 PF08241.7 EAU88252.2 - 0.00022 21.6 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAC PF01849.13 EAU88253.1 - 2.7e-20 71.6 0.0 5.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EAU88253.1 - 0.0019 18.0 0.2 0.006 16.3 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EAU88253.1 - 0.027 13.9 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF3573 PF12097.3 EAU88254.2 - 0.45 9.0 8.2 0.033 12.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3573) ATG16 PF08614.6 EAU88254.2 - 5.9 6.6 35.5 0.096 12.5 7.8 4.0 3 1 0 4 4 4 0 Autophagy protein 16 (ATG16) HSP90 PF00183.13 EAU88255.1 - 1.4e-257 855.3 30.5 1.8e-257 854.9 21.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EAU88255.1 - 1.2e-11 44.3 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EAU88255.1 - 4.4e-10 39.3 0.2 4.4e-10 39.3 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C37 PF05416.7 EAU88255.1 - 1.7 6.8 7.0 3 6.0 0.0 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase DUF45 PF01863.12 EAU88255.1 - 2.3 7.9 12.9 6.4 6.5 5.3 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 UBN2_2 PF14227.1 EAU88275.2 - 1.1e-05 24.9 1.0 2.5e-05 23.8 0.0 2.2 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EAU88275.2 - 1.8e-05 24.0 0.4 3.9e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2 PF14223.1 EAU88275.2 - 0.00052 19.7 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Rtf2 PF04641.7 EAU88275.2 - 0.39 9.8 11.5 0.62 9.2 8.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Neur_chan_memb PF02932.11 EAU88275.2 - 6.3 6.6 7.0 9.7 6.0 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HA2 PF04408.18 EAU88277.2 - 1.8e-18 66.4 0.0 3.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAU88277.2 - 5.9e-18 64.7 0.0 1.1e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAU88277.2 - 1.5e-13 50.3 0.0 3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU88277.2 - 3e-06 26.8 0.0 7.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU88277.2 - 3.1e-05 24.1 0.0 7.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EAU88277.2 - 0.0045 16.8 0.1 0.098 12.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EAU88277.2 - 0.014 14.2 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EAU88277.2 - 0.016 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 EAU88277.2 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAU88277.2 - 0.038 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 EAU88277.2 - 0.039 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EAU88277.2 - 0.048 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 EAU88277.2 - 0.049 13.3 0.0 0.089 12.4 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 EAU88277.2 - 0.067 12.6 0.1 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 EAU88277.2 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 EAU88277.2 - 0.14 11.2 0.1 0.41 9.7 0.0 1.7 1 1 1 2 2 2 0 Zeta toxin DUF572 PF04502.8 EAU88278.1 - 2.6e-65 220.7 11.5 3e-65 220.5 7.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 EAU88278.1 - 0.0015 18.1 1.1 0.29 10.8 0.1 2.3 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 EAU88278.1 - 0.038 13.4 0.1 0.084 12.3 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 EAU88278.1 - 0.1 12.4 0.2 0.42 10.4 0.1 2.1 2 1 0 2 2 2 0 Benyvirus 14KDa protein C1_3 PF07649.7 EAU88278.1 - 0.19 11.7 1.6 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 C1-like domain Lar_restr_allev PF14354.1 EAU88278.1 - 1.6 9.1 5.3 1.7 9.0 1.5 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Mis14 PF08641.7 EAU88279.2 - 3.8e-05 23.7 4.4 7e-05 22.9 2.7 1.9 1 1 0 1 1 1 1 Kinetochore protein Mis14 like HWE_HK PF07536.9 EAU88279.2 - 0.048 14.1 0.2 0.048 14.1 0.1 2.4 3 0 0 3 3 3 0 HWE histidine kinase BLOC1_2 PF10046.4 EAU88279.2 - 0.055 13.6 3.5 0.45 10.6 0.0 2.8 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 EAU88279.2 - 0.089 11.7 3.2 0.24 10.2 2.2 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 EAU88279.2 - 4.6 7.4 9.6 19 5.4 1.3 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Gar1 PF04410.9 EAU88280.1 - 2.8e-37 127.5 0.1 4.9e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region AAA PF00004.24 EAU88281.2 - 1.1e-48 164.7 0.0 2.4e-45 153.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU88281.2 - 3.5e-06 27.8 0.0 0.0044 17.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAU88281.2 - 0.00011 22.3 0.1 0.0098 16.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAU88281.2 - 0.00015 21.2 0.3 0.013 14.8 0.2 2.8 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 EAU88281.2 - 0.00023 21.0 0.0 0.09 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU88281.2 - 0.00029 20.8 2.6 0.017 15.1 0.1 3.5 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EAU88281.2 - 0.00033 19.7 0.0 0.0065 15.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EAU88281.2 - 0.00054 19.6 0.1 0.014 15.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EAU88281.2 - 0.00071 19.2 0.5 0.0032 17.1 0.0 2.4 3 0 0 3 3 1 1 Part of AAA domain IstB_IS21 PF01695.12 EAU88281.2 - 0.00071 19.0 0.1 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EAU88281.2 - 0.0034 17.3 0.0 0.015 15.2 0.0 2.1 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) KaiC PF06745.8 EAU88281.2 - 0.0037 16.4 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 KaiC RNA_helicase PF00910.17 EAU88281.2 - 0.0043 17.2 0.0 0.071 13.2 0.0 2.4 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 EAU88281.2 - 0.0065 15.2 0.0 0.014 14.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus Parvo_NS1 PF01057.12 EAU88281.2 - 0.007 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EAU88281.2 - 0.0073 15.7 0.0 0.84 9.0 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.1 EAU88281.2 - 0.01 16.1 0.0 0.067 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EAU88281.2 - 0.015 14.4 0.1 0.04 13.0 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 EAU88281.2 - 0.017 15.0 0.0 0.097 12.5 0.0 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PhoH PF02562.11 EAU88281.2 - 0.026 13.7 0.0 0.076 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 EAU88281.2 - 0.026 14.1 0.1 0.4 10.2 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EAU88281.2 - 0.032 13.8 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EAU88281.2 - 0.073 11.9 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EAU88281.2 - 0.1 12.3 0.1 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 EAU88281.2 - 0.11 12.3 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EAU88281.2 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EAU88281.2 - 0.14 11.7 1.6 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAU88281.2 - 0.19 10.8 0.0 0.52 9.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 EAU88281.2 - 1.1 8.8 4.0 15 5.1 0.0 3.3 4 0 0 4 4 4 0 NACHT domain PhoD PF09423.5 EAU88282.1 - 2.1e-39 135.3 5.0 3.5e-38 131.3 3.4 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase DUF1690 PF07956.6 EAU88283.2 - 1.9e-06 27.9 1.7 9.4e-06 25.6 1.2 1.8 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) Pyrid_oxidase_2 PF13883.1 EAU88283.2 - 0.018 14.7 0.1 0.72 9.5 0.0 2.1 1 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase LUC7 PF03194.10 EAU88283.2 - 0.036 13.5 1.8 0.039 13.4 1.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF1843 PF08898.5 EAU88283.2 - 0.064 13.3 1.7 1 9.4 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Sigma70_ner PF04546.8 EAU88283.2 - 0.16 11.5 6.2 0.33 10.5 4.1 1.6 1 1 1 2 2 2 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 EAU88283.2 - 0.27 10.9 5.1 0.32 10.6 3.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myb_Cef PF11831.3 EAU88285.1 - 1.5e-55 187.9 0.2 1.5e-55 187.9 0.1 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EAU88285.1 - 1.2e-20 73.2 5.7 8.1e-11 41.8 0.4 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAU88285.1 - 1.4e-17 63.4 7.8 3e-12 46.4 2.3 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Fungal_trans PF04082.13 EAU88286.2 - 3.6e-20 71.9 0.3 7e-20 70.9 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 EAU88287.2 - 4e-06 26.4 3.1 0.00027 20.6 0.3 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ADK PF00406.17 EAU88288.2 - 5.2e-43 146.5 0.0 1.2e-42 145.3 0.0 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EAU88288.2 - 6.7e-07 29.6 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU88288.2 - 7e-06 26.8 0.0 1.1e-05 26.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU88288.2 - 8.5e-05 22.4 0.0 0.00044 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EAU88288.2 - 0.00016 21.1 0.2 0.46 9.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Aldolase_II PF00596.16 EAU88311.1 - 2e-42 144.9 0.0 2.5e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain dsDNA_bind PF01984.15 EAU88312.2 - 2.5e-25 88.5 3.4 3e-25 88.2 2.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DLD PF14878.1 EAU88312.2 - 0.076 13.1 0.5 0.13 12.3 0.4 1.4 1 1 0 1 1 1 0 Death-like domain of SPT6 Cofilin_ADF PF00241.15 EAU88317.2 - 4.5e-11 42.7 0.1 3.1e-09 36.7 0.0 2.6 3 0 0 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein Lysine_decarbox PF03641.9 EAU88318.2 - 1e-35 122.4 0.1 1.4e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase tRNA-synt_1b PF00579.20 EAU88319.1 - 6.3e-23 81.3 0.0 1.5e-22 80.0 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) RRM_1 PF00076.17 EAU88320.2 - 0.0052 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU88320.2 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 EAU88321.2 - 8.6e-58 195.5 0.0 2e-57 194.3 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EAU88321.2 - 1.4e-32 112.0 0.0 3e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HSA PF07529.8 EAU88322.2 - 4.9e-17 61.4 2.1 2.1e-16 59.4 1.5 2.1 1 0 0 1 1 1 1 HSA Myb_DNA-bind_6 PF13921.1 EAU88322.2 - 4.7e-09 36.2 0.1 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAU88322.2 - 3.5e-07 30.1 0.0 7.6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cellulase PF00150.13 EAU88323.1 - 7.7e-10 38.4 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 EAU88323.1 - 0.0077 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF4366 PF14283.1 EAU88323.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF515 PF04415.7 EAU88323.1 - 0.035 12.3 0.0 0.053 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Radical_SAM PF04055.16 EAU88323.1 - 0.13 12.3 0.0 0.52 10.4 0.0 1.8 2 0 0 2 2 2 0 Radical SAM superfamily ETRAMP PF09716.5 EAU88323.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) IATP PF04568.7 EAU88324.1 - 4.1e-09 36.3 1.7 7.7e-09 35.4 1.1 1.5 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF1120 PF06551.7 EAU88324.1 - 0.059 13.6 0.1 0.076 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) NmrA PF05368.8 EAU88325.1 - 2.1e-44 151.5 0.0 2.3e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EAU88325.1 - 5.2e-13 49.3 0.0 8.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EAU88325.1 - 1.9e-05 24.3 0.2 3.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAU88325.1 - 2.4e-05 24.3 0.4 4e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EAU88325.1 - 3.7e-05 23.2 0.1 0.00012 21.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAU88325.1 - 0.00016 20.4 0.0 0.00026 19.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EAU88325.1 - 0.07 12.0 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein Acetyltransf_13 PF13880.1 EAU88327.1 - 4.9e-16 58.2 0.0 1e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EAU88327.1 - 1.6e-05 24.3 0.8 2.7e-05 23.6 0.6 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EAU88327.1 - 9e-05 22.4 0.0 0.00022 21.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU88327.1 - 0.004 17.2 0.0 0.012 15.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAU88327.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CDC45 PF02724.9 EAU88329.2 - 1.2e-181 604.9 0.0 1.3e-181 604.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Spt5_N PF11942.3 EAU88329.2 - 0.025 15.1 12.3 0.054 14.1 8.5 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Sec_GG PF07549.9 EAU88329.2 - 0.073 12.3 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif Scramblase PF03803.10 EAU88330.2 - 5.8e-26 90.9 0.0 4.6e-22 78.1 0.0 2.0 2 0 0 2 2 2 2 Scramblase GTP_EFTU PF00009.22 EAU88331.2 - 1.3e-35 122.5 0.9 8.3e-35 119.9 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EAU88331.2 - 1.5e-28 98.8 1.4 3.6e-28 97.6 1.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EAU88331.2 - 7.4e-07 29.2 6.4 7.2e-06 26.0 0.2 3.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 IF2_N PF04760.10 EAU88331.2 - 1.5e-05 24.5 0.0 3.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EAU88331.2 - 2e-05 24.4 0.7 6.4e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EAU88331.2 - 0.002 17.6 0.4 0.02 14.3 0.3 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EAU88331.2 - 0.0023 17.5 8.9 0.088 12.4 0.1 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 4 Arf PF00025.16 EAU88331.2 - 0.0023 17.1 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EAU88331.2 - 0.0079 16.6 0.3 0.022 15.2 0.1 1.9 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EAU88331.2 - 0.012 14.7 0.1 0.036 13.2 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 EAU88331.2 - 0.044 13.4 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CHORD PF04968.7 EAU88332.2 - 2e-31 108.0 8.6 1.6e-22 79.4 2.5 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 EAU88332.2 - 0.0058 17.1 0.8 0.0097 16.4 0.6 1.3 1 0 0 1 1 1 1 CS domain Roughex PF06020.6 EAU88332.2 - 4.1 5.9 5.9 5.5 5.5 0.1 2.1 1 1 1 2 2 2 0 Drosophila roughex protein Mito_carr PF00153.22 EAU88333.2 - 0.0045 16.6 0.0 0.028 14.1 0.0 2.2 2 1 0 2 2 2 1 Mitochondrial carrier protein zf-Mss51 PF13824.1 EAU88336.1 - 5.7e-23 80.5 10.0 1.1e-22 79.5 6.9 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.1 EAU88336.1 - 0.033 14.4 4.5 0.074 13.3 3.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar IGPD PF00475.13 EAU88337.1 - 1.3e-55 187.2 0.5 2.6e-40 137.6 0.0 2.2 2 0 0 2 2 2 2 Imidazoleglycerol-phosphate dehydratase Peptidase_M24 PF00557.19 EAU88339.2 - 9.1e-19 67.8 0.9 2.8e-17 62.9 0.0 2.2 1 1 1 2 2 2 2 Metallopeptidase family M24 MFS_1 PF07690.11 EAU88341.2 - 1.5e-23 83.0 25.5 2.7e-23 82.2 17.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU88341.2 - 1.3e-05 24.0 15.0 4.9e-05 22.0 10.4 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EAU88341.2 - 0.022 12.9 0.2 0.022 12.9 0.1 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) EF-hand_1 PF00036.27 EAU88343.1 - 2.3e-23 79.6 0.1 7.2e-06 24.9 0.0 4.5 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EAU88343.1 - 5.2e-20 69.4 0.3 4.7e-06 26.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAU88343.1 - 1.3e-18 65.3 0.1 0.00099 18.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAU88343.1 - 2e-18 66.2 0.0 9.1e-08 32.1 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EAU88343.1 - 5.6e-14 51.5 2.7 3.9e-08 32.7 0.1 4.2 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_2 PF09068.6 EAU88343.1 - 0.016 15.3 0.0 11 6.1 0.0 3.2 3 1 1 4 4 4 0 EF hand gpW PF02831.10 EAU88343.1 - 0.055 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 gpW Toprim PF01751.17 EAU88343.1 - 0.057 13.4 0.0 1.9 8.5 0.0 2.4 1 1 1 2 2 2 0 Toprim domain Toprim_2 PF13155.1 EAU88343.1 - 0.095 13.0 0.1 11 6.4 0.0 3.0 1 1 0 1 1 1 0 Toprim-like HAD_2 PF13419.1 EAU88345.1 - 1.2e-17 64.6 0.0 5.6e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU88345.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EAU88345.1 - 0.008 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.21 EAU88345.1 - 0.028 14.8 0.0 0.095 13.1 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ras PF00071.17 EAU88348.2 - 2.7e-65 218.6 0.8 3.2e-65 218.4 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU88348.2 - 2.3e-21 76.4 0.0 3.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU88348.2 - 3.2e-17 62.3 0.2 3.9e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU88348.2 - 1.1e-06 28.2 0.1 2.2e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAU88348.2 - 2e-06 27.1 0.0 2.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU88348.2 - 3.5e-05 23.7 0.1 5.9e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EAU88348.2 - 4.2e-05 22.8 0.1 5.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EAU88348.2 - 0.00072 18.7 0.2 0.056 12.6 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAU88348.2 - 0.0012 19.0 0.0 0.0028 17.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EAU88348.2 - 0.0015 18.6 0.1 0.41 10.8 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EAU88348.2 - 0.0079 15.4 0.1 0.055 12.7 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EAU88348.2 - 0.015 15.3 0.2 0.052 13.5 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EAU88348.2 - 0.022 14.4 0.0 0.04 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EAU88348.2 - 0.031 13.7 0.6 0.083 12.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.13 EAU88348.2 - 0.062 12.3 0.0 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 EAU88348.2 - 0.074 13.3 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EAU88348.2 - 0.1 12.0 0.0 1.1 8.7 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SOR_SNZ PF01680.12 EAU88352.1 - 1.4e-114 380.8 5.7 2e-114 380.3 4.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EAU88352.1 - 8.9e-10 38.0 3.9 2.6e-07 29.9 0.0 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EAU88352.1 - 3.6e-05 22.7 0.2 0.1 11.4 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EAU88352.1 - 0.0019 17.2 0.2 0.13 11.1 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EAU88352.1 - 0.0029 16.8 4.9 0.011 14.8 0.1 2.3 2 0 0 2 2 2 1 Nitronate monooxygenase IGPS PF00218.16 EAU88352.1 - 0.0069 15.4 0.1 0.054 12.5 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 EAU88352.1 - 0.007 15.6 0.5 0.22 10.7 0.0 2.5 2 1 1 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.13 EAU88352.1 - 0.016 14.1 0.0 0.039 12.8 0.0 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PEP_mutase PF13714.1 EAU88352.1 - 0.039 13.1 1.0 0.12 11.5 0.2 2.0 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase RNA_pol_Rpc4 PF05132.9 EAU88352.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2984 PF11203.3 EAU88352.1 - 0.12 12.5 0.1 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) Img2 PF05046.9 EAU88353.1 - 6.8e-20 71.0 0.0 8.2e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) RHIM PF12721.2 EAU88353.1 - 0.075 13.4 0.2 0.098 13.0 0.1 1.2 1 0 0 1 1 1 0 RIP homotypic interaction motif Piwi PF02171.12 EAU88354.2 - 3.5e-61 206.8 0.0 2.1e-60 204.2 0.0 2.0 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 EAU88354.2 - 5.7e-08 32.1 0.0 1.7e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EAU88354.2 - 1.5e-07 30.6 0.0 4.6e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) DUF1708 PF08101.6 EAU88356.2 - 3.2e-20 72.3 0.6 3.6e-19 68.9 0.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EAU88356.2 - 0.00022 20.8 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain SKG6 PF08693.5 EAU88357.2 - 0.34 10.2 1.3 0.68 9.2 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 EAU88357.2 - 0.43 10.2 1.0 0.72 9.5 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain Lactamase_B PF00753.22 EAU88359.2 - 9e-24 84.2 0.8 1.3e-23 83.6 0.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EAU88359.2 - 0.0015 18.1 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Got1 PF04178.7 EAU88360.1 - 1.4e-20 73.6 23.7 1.8e-20 73.2 16.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1212 PF06738.7 EAU88360.1 - 0.8 9.1 11.1 1.1 8.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Rad21_Rec8 PF04824.11 EAU88361.2 - 2.9e-12 45.5 0.0 5.5e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EAU88361.2 - 0.025 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 ScpA/B protein TruB_C PF09142.6 EAU88361.2 - 0.16 11.6 1.8 9.9 5.8 0.1 2.8 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal DUF2703 PF10865.3 EAU88363.2 - 0.21 11.5 1.7 0.21 11.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) LSR PF05624.9 EAU88363.2 - 4.2 7.1 10.6 4.2 7.1 7.4 1.2 1 1 0 1 1 1 0 Lipolysis stimulated receptor (LSR) PPTA PF01239.17 EAU88364.2 - 1.4e-42 141.2 10.9 4.1e-10 38.5 0.1 6.5 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_11 PF13414.1 EAU88365.2 - 1.7e-09 37.1 17.8 0.096 12.3 0.0 7.6 9 0 0 9 9 8 4 TPR repeat TPR_14 PF13428.1 EAU88365.2 - 1.8e-09 37.3 13.6 0.44 11.3 0.0 11.3 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU88365.2 - 9.4e-09 35.0 8.9 0.98 9.4 0.0 7.3 6 2 0 6 6 6 3 Tetratricopeptide repeat Suf PF05843.9 EAU88365.2 - 2e-05 24.5 8.6 0.0088 15.7 0.1 4.9 3 2 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_7 PF13176.1 EAU88365.2 - 0.00012 21.5 5.3 2.1 8.3 0.0 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU88365.2 - 0.00085 19.9 24.4 0.35 11.6 0.0 7.6 9 1 0 9 9 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU88365.2 - 0.0012 19.1 16.7 2.2 8.6 0.0 6.9 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU88365.2 - 0.013 15.3 0.1 0.23 11.4 0.0 8.6 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU88365.2 - 0.1 12.2 7.8 3.6 7.3 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 EAU88365.2 - 0.11 12.8 0.4 1.3 9.4 0.0 3.1 3 0 0 3 3 2 0 Pentatricopeptide repeat domain HAT PF02184.11 EAU88365.2 - 0.17 11.6 6.6 2.2 8.1 0.0 5.5 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat Mad3_BUB1_I PF08311.7 EAU88365.2 - 0.2 11.4 15.2 1.9 8.3 0.2 7.0 7 2 2 9 9 9 0 Mad3/BUB1 homology region 1 TPR_4 PF07721.9 EAU88365.2 - 0.39 11.2 0.0 0.39 11.2 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat AATF-Che1 PF13339.1 EAU88365.2 - 1.2 9.3 5.5 3.8 7.6 0.0 4.0 4 0 0 4 4 4 0 Apoptosis antagonizing transcription factor TPR_17 PF13431.1 EAU88365.2 - 2.5 8.5 14.6 1e+02 3.5 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat Brix PF04427.13 EAU88367.1 - 1.9e-48 164.6 0.0 2.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain Nop25 PF09805.4 EAU88367.1 - 0.073 13.1 22.2 0.17 11.9 15.4 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Dicty_REP PF05086.7 EAU88367.1 - 1.7 6.2 6.6 2.4 5.8 4.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BUD22 PF09073.5 EAU88367.1 - 4 6.4 27.8 8.5 5.3 19.3 1.5 1 0 0 1 1 1 0 BUD22 Cyto_heme_lyase PF01265.12 EAU88368.2 - 8.6e-80 268.0 0.1 1.2e-79 267.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase NMO PF03060.10 EAU88369.1 - 7.7e-70 235.6 2.1 9.3e-70 235.3 1.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAU88369.1 - 3e-06 26.3 3.2 0.0094 14.8 0.5 2.9 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EAU88369.1 - 0.0012 17.7 3.6 0.0012 17.7 2.5 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DUF3445 PF11927.3 EAU88370.2 - 5.3e-70 235.6 0.0 6.5e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) WD40 PF00400.27 EAU88371.2 - 2.9e-14 52.3 0.6 6.9e-06 25.7 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.3 EAU88371.2 - 0.00033 18.9 0.1 0.00034 18.8 0.1 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Peptidase_C97 PF05903.9 EAU88372.1 - 7.3e-39 132.9 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EAU88372.1 - 5.4e-25 87.7 0.0 8.2e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EAU88372.1 - 5.6e-15 54.8 0.0 1.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EAU88372.1 - 1.2e-06 28.7 0.2 2.4e-05 24.4 0.2 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 EAU88372.1 - 0.049 13.1 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EAU88372.1 - 0.084 12.8 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin GPI-anchored PF10342.4 EAU88373.1 - 0.0061 17.0 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Endonuclease_NS PF01223.18 EAU88376.2 - 2.6e-52 177.4 0.0 3.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Not1 PF04054.10 EAU88377.2 - 3.1e-119 398.2 0.0 7e-119 397.0 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EAU88377.2 - 3.3e-54 182.5 0.6 9.8e-54 181.0 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Sugar_tr PF00083.19 EAU88377.2 - 3.1e-53 180.9 12.6 1.2e-49 169.1 8.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU88377.2 - 6.5e-12 44.8 28.8 9.1e-07 27.9 5.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.19 EAU88378.2 - 9.2e-59 199.3 0.2 3.2e-57 194.3 0.1 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EAU88378.2 - 3.2e-14 52.7 0.3 7.3e-14 51.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_31 PF01055.21 EAU88378.2 - 0.0017 17.2 0.3 0.002 17.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 hDGE_amylase PF14701.1 EAU88378.2 - 0.034 13.0 0.3 0.071 11.9 0.0 1.5 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme Tubulin PF00091.20 EAU88379.2 - 5.6e-74 248.6 0.0 9.6e-74 247.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EAU88379.2 - 3.2e-47 159.6 0.1 6.2e-47 158.7 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EAU88379.2 - 0.00038 20.4 0.0 0.0018 18.3 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EAU88379.2 - 0.005 16.3 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Senescence PF06911.7 EAU88380.1 - 4.7e-15 55.7 14.1 2e-14 53.6 9.8 2.0 1 1 0 1 1 1 1 Senescence-associated protein MBF1 PF08523.5 EAU88381.2 - 4.3e-23 81.1 2.7 8.8e-23 80.1 1.9 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EAU88381.2 - 1.1e-14 53.9 0.1 1.9e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EAU88381.2 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EAU88381.2 - 1.2e-06 28.5 0.0 2.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 EAU88381.2 - 0.0037 16.8 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Tetraspannin PF00335.15 EAU88382.1 - 4.6e-08 32.6 10.2 7e-08 32.0 7.1 1.3 1 0 0 1 1 1 1 Tetraspanin family p53-inducible11 PF14936.1 EAU88382.1 - 0.19 11.6 6.4 0.27 11.1 3.9 1.6 1 1 0 1 1 1 0 Tumour protein p53-inducible protein 11 DUF805 PF05656.9 EAU88382.1 - 3.2 7.6 13.1 14 5.5 7.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF3321 PF11968.3 EAU88383.1 - 2.4e-65 220.2 0.0 2.9e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EAU88383.1 - 0.00012 21.7 0.0 0.00024 20.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF1802 PF08819.6 EAU88383.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) YcfA PF07927.7 EAU88383.1 - 0.096 12.6 1.1 9.8 6.1 0.1 2.6 2 0 0 2 2 2 0 YcfA-like protein Spt4 PF06093.8 EAU88384.1 - 3.4e-31 106.9 0.1 4.1e-31 106.6 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 EAU88384.1 - 0.036 13.9 0.1 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 RNHCP domain Rpr2 PF04032.11 EAU88384.1 - 0.04 13.7 0.6 0.061 13.2 0.4 1.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain 5_nucleotid_C PF02872.13 EAU88385.1 - 1.8e-26 93.0 0.0 3.7e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EAU88385.1 - 3.6e-08 33.0 0.1 9.4e-08 31.6 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF457 PF04307.9 EAU88386.2 - 0.027 13.8 0.6 0.034 13.4 0.4 1.3 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) SH2 PF00017.19 EAU88386.2 - 0.046 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 SH2 domain DUF2420 PF10336.4 EAU88387.2 - 4.7e-09 35.8 0.2 9.1e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) RNA_pol_Rpc82 PF05645.8 EAU88388.2 - 6.4e-18 65.2 0.5 6.4e-18 65.2 0.4 2.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.12 EAU88388.2 - 2.1e-08 33.6 0.0 1.8e-06 27.4 0.0 3.1 2 1 0 2 2 2 1 TFIIE alpha subunit HTH_9 PF08221.6 EAU88388.2 - 1.9e-05 24.4 0.2 0.17 11.7 0.0 3.7 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain SPT16 PF08644.6 EAU88389.2 - 1.5e-55 187.2 0.1 4.8e-55 185.5 0.1 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EAU88389.2 - 1.6e-37 128.5 0.3 5e-37 126.9 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EAU88389.2 - 2.1e-20 73.1 0.0 4.1e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EAU88389.2 - 8.5e-20 70.5 0.1 4e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 EAU88389.2 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) DUF2834 PF11196.3 EAU88390.1 - 0.006 16.7 9.2 0.071 13.2 0.2 3.1 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) DEAD PF00270.24 EAU88392.2 - 5.3e-22 78.0 0.0 9.5e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU88392.2 - 9.4e-12 44.6 0.1 1.6e-10 40.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EAU88392.2 - 1.1e-10 41.8 2.7 3.9e-10 40.1 1.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 EAU88392.2 - 0.016 15.1 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 DNA replication factor CDT1 like JAB PF01398.16 EAU88392.2 - 0.065 12.9 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase PF00069.20 EAU88393.1 - 9.6e-25 87.2 0.0 1.5e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88393.1 - 4.4e-14 52.1 0.0 9.4e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EAU88393.1 - 0.16 12.1 0.1 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat DUF220 PF02713.9 EAU88393.1 - 0.27 10.9 0.1 0.71 9.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF220 Hydrophobin PF01185.13 EAU88395.2 - 0.00016 22.0 1.2 0.00039 20.8 0.8 1.6 1 1 0 1 1 1 1 Fungal hydrophobin NAD_binding_2 PF03446.10 EAU88397.1 - 1.1e-38 132.6 0.1 1.6e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EAU88397.1 - 2e-32 111.8 0.0 3.7e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EAU88397.1 - 0.0029 18.0 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EAU88397.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EAU88398.2 - 1.1e-05 24.9 0.1 4.6e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cytochrom_B561 PF03188.11 EAU88399.2 - 8e-11 41.9 8.2 8e-11 41.9 5.7 2.0 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EAU88399.2 - 0.014 15.1 0.2 0.014 15.1 0.1 3.5 4 0 0 4 4 4 0 PepSY-associated TM helix DUF4271 PF14093.1 EAU88399.2 - 0.016 14.8 0.2 0.038 13.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF2306 PF10067.4 EAU88399.2 - 1.1 9.4 12.8 0.45 10.6 0.8 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Sec7 PF01369.15 EAU88400.2 - 3e-62 209.6 0.1 5.5e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EAU88400.2 - 7.1e-16 58.0 3.4 7.1e-16 58.0 2.3 3.4 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EAU88400.2 - 0.007 15.8 0.7 0.91 9.0 0.0 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Herp-Cyclin PF09241.5 EAU88400.2 - 0.069 13.4 0.6 1.4 9.2 0.1 2.8 2 0 0 2 2 2 0 Herpesviridae viral cyclin IstB_IS21 PF01695.12 EAU88400.2 - 0.098 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Proteasome PF00227.21 EAU88401.2 - 2.8e-60 202.8 0.0 3.9e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAU88401.2 - 9.3e-09 34.4 0.1 9.3e-09 34.4 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.8 EAU88402.2 - 1.5e-41 141.9 0.0 1.1e-40 139.1 0.0 2.0 2 0 0 2 2 2 1 Peptidase family C78 MAT1 PF06391.8 EAU88403.2 - 9.3e-50 168.9 17.1 1.2e-49 168.6 11.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 DUF3887 PF13026.1 EAU88403.2 - 0.023 14.9 0.4 0.023 14.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) TAF4 PF05236.9 EAU88403.2 - 0.081 12.1 11.3 0.13 11.5 7.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AAA_23 PF13476.1 EAU88403.2 - 0.17 12.1 6.2 0.23 11.7 4.3 1.2 1 0 0 1 1 1 0 AAA domain Rtf2 PF04641.7 EAU88403.2 - 3.4 6.8 10.9 6.1 5.9 7.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Nucleoporin_FG PF13634.1 EAU88404.2 - 1.4e-05 25.2 98.0 0.00015 21.9 16.3 10.3 4 1 7 11 11 11 4 Nucleoporin FG repeat region DUF974 PF06159.8 EAU88405.2 - 1.2e-61 208.4 0.0 1.6e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) V-ATPase_H_N PF03224.9 EAU88406.1 - 2.4e-75 253.5 0.9 2.4e-47 161.5 0.1 2.6 2 1 1 3 3 3 2 V-ATPase subunit H V-ATPase_H_C PF11698.3 EAU88406.1 - 5.6e-46 155.3 0.8 7.7e-45 151.6 0.1 2.3 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.8 EAU88406.1 - 3e-06 26.5 0.3 6.6e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.1 EAU88406.1 - 4.7e-05 23.5 0.0 0.012 15.9 0.0 2.8 3 1 0 3 3 3 1 HEAT repeats Arm PF00514.18 EAU88406.1 - 0.00013 21.6 1.0 6.3 6.7 0.2 4.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EAU88406.1 - 0.00042 20.1 0.3 0.13 12.4 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat MRP-L46 PF11788.3 EAU88407.1 - 3.1e-17 63.2 0.1 6.4e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EAU88407.1 - 5.3e-09 35.8 0.0 1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_5 PF12695.2 EAU88408.2 - 7.6e-09 35.4 0.1 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU88408.2 - 1.4e-05 25.1 5.7 4.1e-05 23.5 3.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU88408.2 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EAU88408.2 - 0.012 14.9 0.1 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase WD40 PF00400.27 EAU88410.2 - 7.4e-49 161.9 5.8 3.6e-10 39.3 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 EAU88410.2 - 5.1e-40 136.9 13.6 3.1e-37 127.9 1.0 3.7 3 1 0 3 3 3 2 Striatin family Nucleoporin_N PF08801.6 EAU88410.2 - 0.0015 17.3 0.0 0.055 12.2 0.0 2.8 2 2 2 4 4 4 1 Nup133 N terminal like vMSA PF00695.14 EAU88410.2 - 2 7.5 6.3 4.4 6.3 4.4 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PDEase_II PF02112.10 EAU88411.1 - 1.3e-52 178.8 0.0 2.6e-52 177.8 0.0 1.5 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EAU88411.1 - 6.1e-12 45.4 0.0 1e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SRP14 PF02290.10 EAU88412.2 - 0.046 13.6 0.7 0.11 12.4 0.5 1.5 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Dicty_REP PF05086.7 EAU88412.2 - 0.39 8.4 3.8 0.52 7.9 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DLIC PF05783.6 EAU88412.2 - 1.5 7.4 2.7 3.1 6.3 1.9 1.6 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) EF-hand_4 PF12763.2 EAU88413.1 - 1.9e-32 111.0 0.0 1.8e-12 46.8 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EAU88413.1 - 5.4e-08 32.8 0.1 0.0012 18.9 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair UBA PF00627.26 EAU88413.1 - 1.1e-06 28.2 0.1 4.5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_1 PF00036.27 EAU88413.1 - 5.7e-06 25.2 2.6 1.3 8.4 0.0 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EAU88413.1 - 0.027 14.3 3.3 17 5.6 0.0 4.4 4 0 0 4 4 4 0 EF-hand domain EF-hand_8 PF13833.1 EAU88413.1 - 0.053 13.1 0.1 1.5 8.4 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain pair UBA_3 PF09288.5 EAU88413.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain MscS_porin PF12795.2 EAU88413.1 - 4.7 6.4 38.6 4.5 6.5 17.3 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain UQ_con PF00179.21 EAU88414.2 - 1.4e-42 144.4 0.0 1.7e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAU88414.2 - 0.00015 21.6 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EAU88414.2 - 0.038 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B R3H PF01424.17 EAU88415.1 - 1.2e-12 47.3 0.0 2.5e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EAU88415.1 - 1.5e-07 31.3 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU88415.1 - 1.7e-07 30.7 0.0 3.9e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU88415.1 - 0.0002 21.1 0.1 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EcsC PF12787.2 EAU88415.1 - 0.072 12.4 1.6 0.12 11.7 1.1 1.2 1 0 0 1 1 1 0 EcsC protein family SUZ-C PF12901.2 EAU88415.1 - 0.48 10.1 5.7 0.072 12.7 0.5 2.3 2 0 0 2 2 2 0 SUZ-C motif LigB PF02900.13 EAU88416.1 - 6.5e-39 133.5 0.0 9.5e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF2172 PF09940.4 EAU88416.1 - 0.15 10.3 0.0 0.32 9.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2172) Pkinase PF00069.20 EAU88417.2 - 2.6e-65 220.1 0.0 3.3e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88417.2 - 4.9e-31 107.7 0.0 6.8e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU88417.2 - 0.0012 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TFIIA PF03153.8 EAU88417.2 - 0.0075 16.2 0.0 0.0093 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit APH PF01636.18 EAU88417.2 - 0.041 13.6 0.1 2.4 7.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RTC PF01137.16 EAU88418.1 - 5e-69 231.5 0.0 5.8e-69 231.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EAU88418.1 - 2e-17 63.0 1.3 9.5e-17 60.8 0.3 2.3 2 1 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CDC50 PF03381.10 EAU88419.1 - 2.6e-91 305.6 0.0 3.5e-91 305.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Racemase_4 PF13615.1 EAU88420.2 - 2.5e-07 30.8 0.0 7.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Putative alanine racemase PHD PF00628.24 EAU88421.2 - 4e-16 58.4 16.6 1.5e-10 40.5 3.8 2.6 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 EAU88421.2 - 0.00098 18.4 0.8 0.061 12.6 0.4 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EAU88421.2 - 0.0018 17.5 8.9 0.13 11.5 0.4 3.1 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EAU88421.2 - 0.0019 17.9 1.0 0.61 9.8 0.0 2.6 2 1 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 EAU88421.2 - 0.0051 16.9 0.6 0.0051 16.9 0.4 1.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EAU88421.2 - 0.0095 15.6 10.1 0.21 11.3 0.2 2.8 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EAU88421.2 - 3.1 7.8 11.2 1.9 8.5 0.4 2.5 2 0 0 2 2 2 0 RING-like domain PGM_PMM_I PF02878.11 EAU88422.2 - 5e-39 132.9 0.0 1.4e-38 131.4 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EAU88422.2 - 1.5e-17 63.7 0.0 3.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EAU88422.2 - 7.9e-17 61.3 0.0 1.3e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EAU88422.2 - 9.6e-05 22.3 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PRP38 PF03371.10 EAU88423.2 - 7.6e-66 220.9 0.5 9.2e-66 220.7 0.4 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.2 EAU88423.2 - 0.75 10.3 50.8 0.31 11.5 20.7 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ribosomal_L18e PF00828.14 EAU88424.1 - 7.4e-24 84.5 0.0 1.1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 IPPT PF01715.12 EAU88425.2 - 9.4e-49 165.7 0.0 9.3e-26 90.3 0.0 2.2 2 0 0 2 2 2 2 IPP transferase AAA_17 PF13207.1 EAU88425.2 - 3.6e-05 24.5 0.3 0.00037 21.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain IPT PF01745.11 EAU88425.2 - 5.2e-05 22.5 0.1 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Isopentenyl transferase AAA_18 PF13238.1 EAU88425.2 - 0.0048 17.1 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU88425.2 - 0.0076 16.3 0.0 0.13 12.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 EAU88425.2 - 0.01 15.2 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain HTH_27 PF13463.1 EAU88425.2 - 0.02 15.2 0.0 0.063 13.5 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain RNA_helicase PF00910.17 EAU88425.2 - 0.02 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EAU88425.2 - 0.12 11.7 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Fasciclin PF02469.17 EAU88426.1 - 1e-33 116.0 3.3 5.7e-21 74.8 0.0 3.9 3 1 0 3 3 3 3 Fasciclin domain ATP-synt_ab PF00006.20 EAU88427.1 - 3.9e-112 372.9 0.0 5.5e-112 372.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAU88427.1 - 5.8e-23 81.5 2.7 1.2e-22 80.5 1.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EAU88427.1 - 2.6e-14 53.1 4.6 6.4e-14 51.9 3.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain E2R135 PF11570.3 EAU88427.1 - 0.0069 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Coiled-coil receptor-binding R-domain of colicin E2 Zn_clus PF00172.13 EAU88431.2 - 0.0005 19.9 17.0 0.00079 19.2 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 EAU88431.2 - 2.8 7.2 11.7 1.1 8.5 1.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator ING PF12998.2 EAU88434.1 - 8.3e-11 42.1 4.2 2e-10 40.8 1.7 2.2 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EAU88434.1 - 1.2e-09 37.7 6.6 2.2e-09 36.8 4.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EAU88434.1 - 0.0021 17.3 0.7 0.0045 16.2 0.5 1.6 1 0 0 1 1 1 1 PHD-finger HSA PF07529.8 EAU88434.1 - 0.044 13.5 1.4 0.066 13.0 0.0 1.9 2 0 0 2 2 2 0 HSA zf-HC5HC2H PF13771.1 EAU88434.1 - 0.076 13.1 0.3 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain UBN2_3 PF14244.1 EAU88434.1 - 0.081 12.4 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type BBS1 PF14779.1 EAU88434.1 - 0.12 11.3 0.6 0.2 10.6 0.4 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 DEAD PF00270.24 EAU88435.1 - 4e-44 150.1 0.0 2.9e-43 147.2 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU88435.1 - 1.4e-22 79.3 0.0 3.6e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU88435.1 - 0.00038 20.3 0.0 0.056 13.2 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EAU88435.1 - 0.0014 18.5 0.1 0.0083 16.0 0.0 2.3 2 1 0 2 2 2 1 Helicase C-terminal domain DUF1253 PF06862.7 EAU88435.1 - 0.0051 15.2 0.0 0.067 11.5 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) DUF2608 PF11019.3 EAU88435.1 - 0.013 14.5 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) SNF2_N PF00176.18 EAU88435.1 - 0.062 12.0 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EAU88435.1 - 0.064 12.5 0.1 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain BBP1_N PF15271.1 EAU88435.1 - 0.3 11.4 3.2 0.57 10.5 2.2 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Asp-B-Hydro_N PF05279.6 EAU88435.1 - 2.1 8.1 12.1 3.6 7.3 8.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GvpL_GvpF PF06386.6 EAU88435.1 - 5.5 6.4 10.2 9.6 5.7 7.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PNK3P PF08645.6 EAU88436.2 - 1.7e-46 157.5 0.0 3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EAU88436.2 - 4.9e-24 84.8 0.1 3.6e-23 82.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU88436.2 - 1.2e-05 26.0 0.0 2.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAU88436.2 - 7e-05 22.0 0.1 0.2 10.7 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin KTI12 PF08433.5 EAU88436.2 - 0.00011 21.4 1.9 0.021 14.0 1.3 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Hydrolase_6 PF13344.1 EAU88436.2 - 0.017 14.9 0.0 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNA_helicase PF00910.17 EAU88436.2 - 0.054 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EAU88436.2 - 0.066 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.1 EAU88436.2 - 0.077 13.2 0.1 1.1 9.5 0.0 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_18 PF13238.1 EAU88436.2 - 0.088 13.1 0.1 0.55 10.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EAU88436.2 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain NUDIX PF00293.23 EAU88437.2 - 2.2e-17 62.9 0.0 2e-15 56.6 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain SDA1 PF05285.7 EAU88438.1 - 4.9e-76 256.0 62.6 3.2e-39 135.0 9.8 4.1 3 1 1 4 4 4 3 SDA1 NUC130_3NT PF08158.7 EAU88438.1 - 2.8e-20 72.3 2.6 9.5e-18 64.2 0.1 2.6 2 0 0 2 2 2 2 NUC130/3NT domain DUF4061 PF13270.1 EAU88438.1 - 0.46 10.6 12.2 0.77 9.8 4.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4061) PGK PF00162.14 EAU88439.2 - 1.2e-152 508.0 0.3 1.3e-152 507.8 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase JmjC PF02373.17 EAU88440.2 - 8.1e-10 38.9 0.3 2.5e-09 37.3 0.2 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EAU88440.2 - 7.2e-08 32.0 9.9 1.3e-07 31.1 6.9 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 EAU88440.2 - 1.6e-05 24.5 0.3 6e-05 22.6 0.2 1.9 1 1 0 1 1 1 1 Cupin-like domain Prok-RING_1 PF14446.1 EAU88440.2 - 0.18 11.5 4.7 0.37 10.5 3.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EAU88440.2 - 0.42 9.9 4.4 0.92 8.8 3.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 EAU88440.2 - 1.3 8.9 7.2 4.7 7.1 5.0 1.9 1 1 0 1 1 1 0 Ring finger domain zf-CHY PF05495.7 EAU88440.2 - 1.6 8.9 5.7 2.9 8.1 4.0 1.4 1 0 0 1 1 1 0 CHY zinc finger Neisseria_TspB PF05616.8 EAU88440.2 - 2.7 6.2 5.5 3.7 5.7 3.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Sel1 PF08238.7 EAU88441.1 - 1.7e-48 161.9 32.2 1.1e-08 35.4 0.0 7.9 8 0 0 8 8 8 7 Sel1 repeat TPR_14 PF13428.1 EAU88441.1 - 0.73 10.6 21.2 0.68 10.7 0.5 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU88441.1 - 1.3 9.5 7.9 5.5 7.6 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat USP7_ICP0_bdg PF12436.3 EAU88443.2 - 7.1e-86 287.4 0.1 2.1e-85 285.9 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EAU88443.2 - 2.8e-70 236.0 2.4 3e-68 229.4 0.3 2.6 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EAU88443.2 - 8.1e-58 195.6 0.2 1.3e-57 194.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU88443.2 - 4.5e-33 114.9 0.0 6.9e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EAU88443.2 - 3.7e-07 30.3 0.0 1.9e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 MATH domain UN_NPL4 PF11543.3 EAU88443.2 - 0.1 12.8 0.3 7.3 6.9 0.1 3.5 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 EAU88444.1 - 6e-48 162.7 0.1 7.2e-48 162.4 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF365 PF04033.7 EAU88444.1 - 0.1 12.5 0.4 0.17 11.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF365) NUDIX PF00293.23 EAU88445.1 - 2.3e-05 24.0 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Citrate_synt PF00285.16 EAU88446.1 - 5.1e-101 337.9 0.0 6.1e-101 337.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 EAU88446.1 - 0.021 14.4 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 XH domain B56 PF01603.15 EAU88448.2 - 1.1e-160 534.7 6.6 1.5e-154 514.5 2.2 2.0 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.2 EAU88448.2 - 0.015 14.7 2.3 3.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Nol1_Nop2_Fmu PF01189.12 EAU88451.2 - 6.9e-91 304.5 0.0 1e-89 300.7 0.0 2.1 1 1 0 1 1 1 1 NOL1/NOP2/sun family PCMT PF01135.14 EAU88451.2 - 0.00062 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 EAU88451.2 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EAU88451.2 - 0.0026 17.3 0.5 0.0042 16.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EAU88451.2 - 0.025 14.5 0.0 0.05 13.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 EAU88451.2 - 0.027 13.9 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SUR7 PF06687.7 EAU88452.1 - 3.1e-19 69.3 10.7 4.5e-19 68.8 7.4 1.3 1 0 0 1 1 1 1 SUR7/PalI family Oxidored_q3 PF00499.15 EAU88452.1 - 0.36 10.6 6.5 0.081 12.6 1.0 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Hexapep PF00132.19 EAU88454.1 - 5.6e-08 31.9 14.1 0.0028 17.0 3.8 4.2 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EAU88454.1 - 6.4e-08 32.1 0.0 1.3e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase W2 PF02020.13 EAU88454.1 - 2.4e-07 30.5 0.0 2.4e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.1 EAU88454.1 - 0.00052 19.5 11.8 0.0054 16.2 1.1 4.0 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EAU88454.1 - 0.0027 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Abhydrolase_3 PF07859.8 EAU88455.1 - 8.3e-11 41.8 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU88455.1 - 2.9e-09 36.8 0.0 4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU88455.1 - 0.00015 21.6 2.4 0.00035 20.5 1.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EAU88455.1 - 0.0063 15.2 0.0 0.0088 14.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EAU88455.1 - 0.011 14.3 0.0 0.02 13.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Aminotran_5 PF00266.14 EAU88456.2 - 9.4e-10 37.7 0.0 1.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.14 EAU88457.2 - 2.5e-17 62.9 0.0 1e-08 34.6 0.0 2.2 1 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EAU88457.2 - 3.3e-08 32.8 0.3 1.1e-07 31.1 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU88457.2 - 1.3e-05 25.1 0.7 3.6e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAU88457.2 - 6.1e-05 23.3 0.0 0.0003 21.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAU88457.2 - 0.0034 16.5 0.2 0.032 13.3 0.2 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAU88457.2 - 0.0076 14.7 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EAU88457.2 - 0.0099 14.7 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 EAU88457.2 - 0.013 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EAU88457.2 - 0.016 15.0 0.0 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAU88457.2 - 0.018 13.9 0.1 0.043 12.7 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU88457.2 - 0.032 13.0 0.1 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain SE PF08491.5 EAU88457.2 - 0.099 11.4 0.3 0.39 9.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 EAU88457.2 - 0.12 11.4 0.0 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 EAU88457.2 - 0.16 11.6 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EAU88457.2 - 0.58 9.9 3.2 0.76 9.5 0.1 2.4 2 0 0 2 2 2 0 ThiF family AT_hook PF02178.14 EAU88458.1 - 0.00018 20.8 60.6 0.11 12.1 6.0 4.9 5 0 0 5 5 5 4 AT hook motif FRG2 PF15315.1 EAU88458.1 - 4.5 7.1 8.0 5.7 6.8 5.5 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 PRKCSH PF07915.8 EAU88459.2 - 9.8e-15 55.1 1.5 2.2e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Secretin_N_2 PF07655.8 EAU88459.2 - 5.1 7.5 12.6 0.57 10.6 0.3 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.20 EAU88460.2 - 8.8e-55 185.6 0.0 4.9e-54 183.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88460.2 - 2.8e-25 88.8 0.0 4.5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU88460.2 - 0.005 16.6 0.6 0.017 14.8 0.1 2.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU88460.2 - 0.074 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DEAD PF00270.24 EAU88461.1 - 2.3e-42 144.3 0.1 1.9e-41 141.3 0.0 2.3 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU88461.1 - 1.6e-23 82.3 0.1 4.1e-23 81.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EAU88461.1 - 8.9e-06 24.7 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EAU88461.1 - 0.0067 16.2 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IF3_C PF00707.17 EAU88461.1 - 0.072 12.8 1.5 0.15 11.7 0.4 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Methyltransf_16 PF10294.4 EAU88462.1 - 2.7e-18 65.9 0.0 4.1e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EAU88462.1 - 0.00022 21.0 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU88462.1 - 0.0017 18.9 0.0 0.0029 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU88462.1 - 0.042 13.8 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EAU88462.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Asn_synthase PF00733.16 EAU88464.1 - 1.5e-65 221.2 0.0 7.7e-48 163.2 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.1 EAU88464.1 - 9.1e-35 119.1 0.0 1.5e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EAU88464.1 - 6.2e-29 100.6 0.0 2.5e-28 98.6 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EAU88464.1 - 4.3e-05 22.4 0.0 0.042 12.5 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 EAU88464.1 - 0.00012 21.3 0.0 0.00028 20.1 0.0 1.5 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.8 EAU88464.1 - 0.0056 15.9 0.0 0.0096 15.2 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 EAU88464.1 - 0.052 12.4 0.0 0.098 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.11 EAU88464.1 - 0.15 10.5 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase SNARE PF05739.14 EAU88465.2 - 1.6e-08 34.1 1.6 1.6e-08 34.1 1.1 3.7 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EAU88465.2 - 2.2e-05 24.5 1.2 2.2e-05 24.5 0.8 2.5 1 1 1 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EAU88465.2 - 0.015 15.3 2.8 0.015 15.3 1.9 2.4 2 1 0 2 2 2 0 Syntaxin-like protein DUF2407_C PF13373.1 EAU88465.2 - 0.078 12.8 3.5 2.6 7.9 0.2 2.3 1 1 1 2 2 2 0 DUF2407 C-terminal domain MCPsignal PF00015.16 EAU88465.2 - 0.18 11.3 6.0 0.26 10.8 0.4 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spectrin PF00435.16 EAU88465.2 - 0.22 11.8 5.4 9 6.6 0.4 3.1 2 1 1 3 3 3 0 Spectrin repeat CDP-OH_P_transf PF01066.16 EAU88466.2 - 5e-20 71.6 5.3 5e-20 71.6 3.7 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase AAA PF00004.24 EAU88467.2 - 1.1e-30 106.5 0.0 2.6e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU88467.2 - 4e-06 26.9 3.1 0.0023 17.9 0.1 4.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 EAU88467.2 - 1.3e-05 25.9 0.1 0.0005 20.8 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU88467.2 - 0.00047 19.8 0.0 0.0023 17.6 0.0 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EAU88467.2 - 0.0005 20.2 0.4 0.02 15.0 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EAU88467.2 - 0.0016 18.2 0.1 0.017 14.8 0.1 3.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EAU88467.2 - 0.002 17.9 0.0 0.0099 15.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EAU88467.2 - 0.0039 16.6 0.4 0.054 12.9 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.1 EAU88467.2 - 0.0057 16.9 0.2 0.13 12.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_11 PF13086.1 EAU88467.2 - 0.0067 16.0 0.5 0.016 14.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EAU88467.2 - 0.0071 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EAU88467.2 - 0.0072 16.2 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EAU88467.2 - 0.0093 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_10 PF12846.2 EAU88467.2 - 0.012 15.0 0.1 0.33 10.3 0.0 2.4 1 1 1 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EAU88467.2 - 0.013 15.4 0.9 0.053 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EAU88467.2 - 0.017 14.5 1.5 2.8 7.2 0.1 3.9 3 1 0 4 4 4 0 AAA domain Sigma54_activ_2 PF14532.1 EAU88467.2 - 0.052 13.5 0.0 0.22 11.5 0.0 2.1 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EAU88467.2 - 0.096 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IPT PF01745.11 EAU88467.2 - 0.1 11.7 0.2 5 6.2 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Mg_chelatase PF01078.16 EAU88467.2 - 0.11 11.5 0.4 0.38 9.8 0.3 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAU88467.2 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EAU88467.2 - 0.19 11.1 2.3 9.6 5.6 0.0 3.4 4 1 0 4 4 4 0 FtsK/SpoIIIE family cobW PF02492.14 EAU88467.2 - 0.27 10.6 0.0 0.53 9.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 EAU88467.2 - 0.3 9.7 0.0 0.45 9.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SMC_Nse1 PF07574.8 EAU88468.2 - 5.7e-29 101.1 0.6 9.8e-20 71.0 0.0 2.3 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EAU88468.2 - 3.6e-09 36.4 8.8 6.8e-09 35.5 6.1 1.5 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 EAU88468.2 - 0.00011 21.9 8.2 0.00018 21.2 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain C1_1 PF00130.17 EAU88468.2 - 0.024 14.3 1.3 0.049 13.3 0.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.1 EAU88468.2 - 0.037 14.0 2.0 0.075 13.0 1.4 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAU88468.2 - 0.08 13.0 5.1 0.18 11.9 3.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-rbx1 PF12678.2 EAU88468.2 - 0.085 12.9 2.6 0.17 12.0 1.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAU88468.2 - 0.16 12.0 8.5 0.27 11.3 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sushi PF00084.15 EAU88468.2 - 0.23 11.8 3.4 0.45 10.9 2.4 1.4 1 0 0 1 1 1 0 Sushi domain (SCR repeat) zf-Apc11 PF12861.2 EAU88468.2 - 0.7 9.7 3.7 1.3 8.9 2.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EAU88468.2 - 1.1 8.9 5.2 3.4 7.3 3.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EAU88468.2 - 1.9 8.2 7.2 5.4 6.7 5.0 1.8 1 1 0 1 1 1 0 PHD-finger CDP-OH_P_transf PF01066.16 EAU88469.2 - 6.3e-12 45.6 4.5 1.1e-11 44.8 3.1 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DNA_primase_lrg PF04104.9 EAU88470.2 - 2.1e-77 259.9 0.0 3.7e-77 259.1 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit SNF2_N PF00176.18 EAU88472.2 - 5.5e-66 222.3 0.0 1.1e-65 221.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EAU88472.2 - 4.1e-39 134.3 11.5 7e-39 133.6 8.0 1.3 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EAU88472.2 - 3.4e-13 49.2 0.0 8.2e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EAU88472.2 - 9.1e-09 34.5 1.3 1.4e-08 33.8 0.0 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EAU88472.2 - 0.0013 18.6 0.0 0.014 15.2 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU88472.2 - 0.0095 16.0 0.0 0.061 13.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain GYF PF02213.11 EAU88473.2 - 1.5e-08 34.1 1.8 3.3e-08 32.9 1.2 1.6 1 0 0 1 1 1 1 GYF domain PQ-loop PF04193.9 EAU88474.2 - 1.7e-41 139.5 6.7 1.6e-21 75.5 0.1 2.5 2 0 0 2 2 2 2 PQ loop repeat CLTH PF10607.4 EAU88474.2 - 1.6e-20 73.2 0.0 2.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain MtN3_slv PF03083.11 EAU88474.2 - 0.055 13.3 0.6 0.16 11.8 0.4 1.7 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange LisH PF08513.6 EAU88474.2 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 LisH Ribosomal_L3 PF00297.17 EAU88475.2 - 7.4e-37 127.1 0.9 1.6e-35 122.7 0.6 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 PBP_like_2 PF12849.2 EAU88475.2 - 0.031 13.7 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 PBP superfamily domain Cpn60_TCP1 PF00118.19 EAU88477.2 - 1.8e-145 485.3 10.4 2.1e-145 485.0 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3599 PF12206.3 EAU88477.2 - 0.068 13.4 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) UFD1 PF03152.9 EAU88478.2 - 4.7e-58 195.1 0.0 6.3e-58 194.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EAU88478.2 - 0.0011 18.5 0.0 0.0037 16.8 0.0 1.8 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 HMA PF00403.21 EAU88479.1 - 1.9e-10 40.7 1.4 2.6e-10 40.2 1.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain CGGC PF08821.6 EAU88479.1 - 0.012 15.6 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 0 CGGC domain AA_permease_2 PF13520.1 EAU88480.2 - 5.2e-66 222.9 40.3 6.4e-66 222.6 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAU88480.2 - 6.7e-37 126.9 34.9 1.2e-36 126.0 24.2 1.4 1 1 0 1 1 1 1 Amino acid permease RNase_PH PF01138.16 EAU88481.2 - 2.2e-33 115.3 0.0 3.1e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAU88481.2 - 1.3e-06 28.1 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PRCC PF10253.4 EAU88482.1 - 8.2e-39 134.1 0.3 8.2e-39 134.1 0.2 2.8 2 1 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2315 PF10231.4 EAU88486.1 - 1.8e-13 50.4 8.9 1.7e-12 47.3 3.8 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2315) SAP PF02037.22 EAU88487.2 - 7.1e-11 41.3 0.7 7.1e-11 41.3 0.5 1.6 2 0 0 2 2 2 1 SAP domain WD40 PF00400.27 EAU88489.1 - 2.1e-13 49.5 8.0 9.9e-05 22.0 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Swi3 PF07962.7 EAU88490.2 - 0.0034 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Methyltransf_PK PF05891.7 EAU88491.2 - 3.7e-48 163.7 0.0 6.2e-46 156.4 0.0 2.3 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EAU88491.2 - 3.5e-05 24.3 0.0 8.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU88491.2 - 0.00033 20.4 0.0 0.00059 19.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU88491.2 - 0.0023 18.3 0.0 0.62 10.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU88491.2 - 0.0027 18.1 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EAU88491.2 - 0.0043 17.3 0.0 0.05 13.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EAU88491.2 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase ADK PF00406.17 EAU88492.1 - 7.6e-46 155.7 0.0 1e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EAU88492.1 - 5.8e-12 45.0 0.0 1e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EAU88492.1 - 5e-06 27.3 0.0 7.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU88492.1 - 3e-05 24.3 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU88492.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAU88492.1 - 0.0012 17.9 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NAD_binding_10 PF13460.1 EAU88493.2 - 1.2e-13 51.4 0.0 3.7e-12 46.6 0.0 2.6 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EAU88493.2 - 8.2e-12 45.0 0.2 1.8e-08 34.1 0.0 2.3 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EAU88493.2 - 1.5e-05 23.8 0.0 0.00034 19.4 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EAU88493.2 - 0.00047 20.1 0.1 0.0011 18.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EAU88493.2 - 0.0094 14.8 0.1 0.24 10.2 0.0 2.8 3 0 0 3 3 3 1 Male sterility protein RmlD_sub_bind PF04321.12 EAU88493.2 - 0.036 12.9 0.0 0.28 10.0 0.0 2.3 3 0 0 3 3 3 0 RmlD substrate binding domain PARP PF00644.15 EAU88494.2 - 2.3e-52 177.4 0.0 4.8e-52 176.4 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EAU88494.2 - 4e-38 130.0 0.1 6.2e-38 129.4 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EAU88494.2 - 5.5e-22 77.5 0.4 1.5e-21 76.0 0.3 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EAU88494.2 - 2.8e-07 30.5 0.3 8.1e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EAU88494.2 - 6.3e-07 29.1 0.2 1.4e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain DPBB_1 PF03330.13 EAU88495.2 - 5e-13 48.8 0.1 1.1e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EAU88495.2 - 0.00073 19.1 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Barwin family Redoxin PF08534.5 EAU88495.2 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Redoxin SCAMP PF04144.8 EAU88496.1 - 1.1e-37 129.5 5.9 1.5e-37 129.2 4.1 1.1 1 0 0 1 1 1 1 SCAMP family NdhL PF10716.4 EAU88496.1 - 0.53 10.0 6.1 1.3 8.8 4.2 1.6 1 0 0 1 1 1 0 NADH dehydrogenase transmembrane subunit RRM_1 PF00076.17 EAU88497.1 - 9.9e-87 284.6 5.9 1.7e-22 78.8 0.8 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU88497.1 - 2.6e-59 197.1 0.7 1.1e-15 57.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU88497.1 - 1.2e-45 153.1 0.9 1.1e-12 47.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EAU88497.1 - 1.1e-29 101.8 2.3 1.8e-29 101.1 1.1 1.8 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EAU88497.1 - 3.5e-05 23.5 9.4 0.053 13.3 1.6 3.6 3 1 1 4 4 4 2 RNA binding motif Limkain-b1 PF11608.3 EAU88497.1 - 0.00069 19.3 2.4 0.94 9.2 0.1 4.0 3 1 1 4 4 4 1 Limkain b1 Nup35_RRM_2 PF14605.1 EAU88497.1 - 0.00082 19.0 0.3 1.2 8.9 0.0 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EAU88497.1 - 0.0062 16.7 0.1 0.23 11.7 0.0 3.2 4 0 0 4 4 4 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 EAU88497.1 - 0.0094 15.4 2.8 10 5.7 0.2 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain DUF4407 PF14362.1 EAU88497.1 - 0.27 10.1 3.1 0.46 9.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1919 PF08942.5 EAU88497.1 - 0.37 10.1 2.6 3.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1919) Methyltransf_18 PF12847.2 EAU88498.2 - 1.2e-06 29.0 0.0 1.7e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU88498.2 - 2.6e-06 27.0 0.0 3.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAU88498.2 - 3.4e-06 26.2 0.0 3.5e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EAU88498.2 - 3.6e-06 26.7 0.0 3.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAU88498.2 - 0.0013 18.8 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EAU88498.2 - 0.0014 18.9 0.0 0.0021 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU88498.2 - 0.0042 17.5 0.0 0.0066 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EAU88498.2 - 0.0051 16.0 0.0 0.0055 15.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase DUF938 PF06080.7 EAU88498.2 - 0.0055 16.2 0.0 0.006 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 EAU88498.2 - 0.0059 17.0 0.0 0.0085 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU88498.2 - 0.0067 15.8 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EAU88498.2 - 0.011 15.0 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 EAU88498.2 - 0.015 14.7 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EAU88498.2 - 0.023 13.8 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EAU88498.2 - 0.058 12.4 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EAU88498.2 - 0.072 12.1 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EAU88498.2 - 0.075 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF221 PF02714.10 EAU88499.1 - 0.029 13.2 0.9 0.037 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 YibE_F PF07907.6 EAU88499.1 - 0.079 12.1 1.3 0.099 11.8 0.9 1.2 1 0 0 1 1 1 0 YibE/F-like protein DUF1206 PF06724.6 EAU88499.1 - 0.26 11.0 3.0 0.15 11.8 0.6 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) CbtB PF09489.5 EAU88499.1 - 0.32 10.9 4.3 0.29 11.0 0.5 2.5 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtB) SRP54 PF00448.17 EAU88500.1 - 4.4e-73 244.9 1.1 7.4e-73 244.1 0.8 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EAU88500.1 - 5e-22 78.1 0.1 5e-22 78.1 0.1 3.9 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 EAU88500.1 - 9.2e-16 57.7 3.4 2e-15 56.6 2.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EAU88500.1 - 2.7e-06 26.9 0.2 6.3e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EAU88500.1 - 6.6e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EAU88500.1 - 0.00031 20.2 0.3 0.0018 17.7 0.2 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EAU88500.1 - 0.00034 20.3 0.0 0.00099 18.8 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EAU88500.1 - 0.0067 15.2 0.8 0.0067 15.2 0.6 2.4 3 1 0 3 3 3 1 ArgK protein AAA_17 PF13207.1 EAU88500.1 - 0.02 15.7 0.0 0.047 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAU88500.1 - 0.024 14.7 0.1 0.099 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 EAU88500.1 - 0.042 12.9 0.1 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF1768 PF08719.6 EAU88500.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) ATP_bind_1 PF03029.12 EAU88500.1 - 0.065 12.7 0.1 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EAU88500.1 - 0.066 12.4 0.5 8 5.6 0.5 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2201 PF09967.4 EAU88500.1 - 2.1 8.4 5.1 3 7.8 0.1 3.4 4 0 0 4 4 4 0 VWA-like domain (DUF2201) WD40 PF00400.27 EAU88501.2 - 1.4e-09 37.4 0.1 0.065 13.1 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat SH2_2 PF14633.1 EAU88502.2 - 4.3e-68 228.6 0.5 4.3e-68 228.6 0.3 2.4 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EAU88502.2 - 6.2e-30 103.6 0.9 6.2e-30 103.6 0.6 2.7 2 0 0 2 2 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EAU88502.2 - 3.1e-28 97.9 0.0 6.4e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EAU88502.2 - 1.6e-26 92.6 0.1 5.7e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EAU88502.2 - 1.5e-19 69.9 39.6 1.5e-19 69.9 27.5 5.6 4 2 1 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EAU88502.2 - 3.2e-14 52.9 0.1 1.1e-13 51.2 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EAU88502.2 - 4.9e-08 32.6 0.0 1.8e-05 24.4 0.0 2.8 2 0 0 2 2 2 1 SH2 domain S1 PF00575.18 EAU88502.2 - 2.4e-07 30.7 1.0 7.1e-07 29.2 0.7 1.8 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 EAU88502.2 - 4.5e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif CTD PF12815.2 EAU88502.2 - 1 9.7 16.4 2.3 8.6 11.3 1.5 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 dCMP_cyt_deam_1 PF00383.17 EAU88503.2 - 2.1e-15 56.1 0.3 3e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AMP-binding PF00501.23 EAU88504.2 - 3.6e-92 308.9 0.0 5.1e-92 308.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EAU88504.2 - 1.2e-88 296.9 0.3 7.9e-31 107.0 0.0 5.0 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EAU88504.2 - 1.2e-25 89.5 0.2 3.3e-07 30.4 0.1 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.8 EAU88504.2 - 0.0013 17.3 0.0 0.63 8.4 0.0 2.2 2 0 0 2 2 2 2 GH3 auxin-responsive promoter AMP-binding_C PF13193.1 EAU88504.2 - 0.0085 17.0 0.0 0.034 15.0 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EAU88504.2 - 0.087 11.2 0.0 19 3.5 0.0 3.1 3 0 0 3 3 3 0 Transferase family K_oxygenase PF13434.1 EAU88505.1 - 1.4e-91 307.0 0.0 1.3e-87 293.9 0.0 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EAU88505.1 - 4.2e-08 33.3 0.0 5.9e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU88505.1 - 1.2e-06 28.4 0.0 7.5e-06 25.8 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAU88505.1 - 7.1e-06 26.2 0.0 1.8e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EAU88505.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EAU88505.1 - 0.019 15.3 0.0 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EAU88505.1 - 0.041 12.0 0.0 0.066 11.3 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.19 EAU88505.1 - 0.11 11.2 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Ribosomal_L24e PF01246.15 EAU88506.2 - 1.1e-30 105.2 3.4 1.1e-30 105.2 2.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 EAU88506.2 - 0.017 14.7 4.6 0.03 13.9 3.2 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif bZIP_Maf PF03131.12 EAU88506.2 - 1.5 9.1 6.5 0.67 10.2 2.9 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor ATG_C PF09333.6 EAU88507.1 - 2.8e-33 113.9 0.2 6.5e-33 112.7 0.1 1.7 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EAU88507.1 - 1.8e-07 30.6 0.0 4.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Lipase_GDSL_2 PF13472.1 EAU88508.1 - 4.7e-06 26.8 0.0 1e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU88508.1 - 7.6e-05 22.6 0.0 0.00026 20.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase NatB_MDM20 PF09797.4 EAU88510.2 - 1.6e-67 227.8 1.4 3.5e-67 226.6 1.0 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 EAU88510.2 - 6.4e-05 23.2 0.2 21 6.1 0.0 5.2 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU88510.2 - 0.00011 22.4 11.8 0.0059 16.9 0.0 4.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU88510.2 - 0.0033 17.0 0.0 0.096 12.3 0.0 3.2 3 1 1 4 4 4 2 TPR repeat BTAD PF03704.12 EAU88510.2 - 0.0044 17.3 0.9 0.049 13.9 0.0 3.1 3 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_16 PF13432.1 EAU88510.2 - 0.0087 16.7 9.4 0.29 11.8 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU88510.2 - 0.053 13.1 0.0 17 5.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TruB_N PF01509.13 EAU88512.1 - 1.8e-44 151.5 0.0 6e-44 149.7 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DHDPS PF00701.17 EAU88513.1 - 7.1e-30 103.6 0.0 2.8e-29 101.6 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PNTB PF02233.11 EAU88517.2 - 4.6e-168 559.7 21.0 4.6e-168 559.7 14.6 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EAU88517.2 - 7.1e-55 185.1 0.7 1.3e-54 184.3 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EAU88517.2 - 6.4e-46 155.7 0.1 3.4e-45 153.3 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EAU88517.2 - 1.9e-31 108.0 3.1 1.9e-31 108.0 2.2 5.0 5 2 0 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EAU88517.2 - 7.3e-05 21.9 1.0 1 8.5 0.0 3.9 5 0 0 5 5 5 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EAU88517.2 - 0.0086 15.6 0.3 0.033 13.7 0.2 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EAU88517.2 - 0.027 14.3 0.4 0.076 12.8 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 EAU88517.2 - 0.17 11.4 0.1 0.98 8.9 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.1 EAU88517.2 - 3.3 7.7 9.7 0.82 9.7 1.8 3.5 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DUF2367 PF10164.4 EAU88521.2 - 2.4e-05 24.0 5.7 2.9e-05 23.8 3.9 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Kinesin PF00225.18 EAU88522.2 - 3.4e-104 348.1 0.0 8.6e-104 346.8 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EAU88522.2 - 0.0004 20.5 3.0 0.0004 20.5 2.1 5.2 5 1 1 6 6 6 1 Kinesin-associated microtubule-binding Elf1 PF05129.8 EAU88523.1 - 4.8e-29 99.8 1.0 5.8e-29 99.6 0.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EAU88523.1 - 0.00053 20.1 0.7 0.00073 19.6 0.5 1.2 1 0 0 1 1 1 1 CHY zinc finger Cytochrom_c3_2 PF14537.1 EAU88523.1 - 0.044 14.1 0.3 0.058 13.7 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C554 PF13435.1 EAU88523.1 - 0.063 13.3 1.4 0.11 12.5 1.0 1.5 1 1 0 1 1 1 0 Cytochrome c554 and c-prime DUF4280 PF14107.1 EAU88523.1 - 0.091 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) Kinesin PF00225.18 EAU88524.2 - 1.4e-112 375.7 0.7 1.4e-112 375.7 0.5 2.6 3 0 0 3 3 3 1 Kinesin motor domain Filament PF00038.16 EAU88524.2 - 2.1 7.7 72.8 0.23 10.8 30.6 3.0 2 1 1 3 3 3 0 Intermediate filament protein PUF PF00806.14 EAU88525.2 - 4e-61 199.1 0.1 4.1e-08 32.2 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TFIID_30kDa PF03540.8 EAU88525.2 - 0.016 15.0 0.7 16 5.4 0.0 3.5 3 0 0 3 3 3 0 Transcription initiation factor TFIID 23-30kDa subunit Sec16_C PF12931.2 EAU88526.2 - 1.5e-68 231.6 0.0 2.2e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EAU88526.2 - 9.5e-33 112.6 0.0 2.3e-32 111.4 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region OST3_OST6 PF04756.8 EAU88527.1 - 2.1e-16 59.8 1.7 3.3e-16 59.2 1.2 1.3 1 0 0 1 1 1 1 OST3 / OST6 family NADH-u_ox-rdase PF10785.4 EAU88527.1 - 0.00028 21.0 0.5 0.00028 21.0 0.3 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Thioredoxin PF00085.15 EAU88527.1 - 0.00032 20.3 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF606 PF04657.8 EAU88527.1 - 0.021 14.9 0.6 0.021 14.9 0.4 2.3 3 0 0 3 3 3 0 Protein of unknown function, DUF606 7TMR-DISM_7TM PF07695.6 EAU88527.1 - 0.71 9.4 8.3 1.9 8.1 5.7 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling PI3_PI4_kinase PF00454.22 EAU88528.2 - 1.3e-32 113.1 0.0 2.3e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EAU88528.2 - 0.07 12.8 0.0 0.22 11.3 0.0 1.9 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Peptidase_M32 PF02074.10 EAU88528.2 - 0.11 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase CytochromB561_N PF09786.4 EAU88528.2 - 2.5 6.4 7.6 3.8 5.8 5.3 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Glyco_transf_15 PF01793.11 EAU88529.2 - 3.9e-114 381.0 7.1 1.3e-74 251.0 3.5 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.17 EAU88530.1 - 3.3e-76 256.1 1.2 3.8e-76 255.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF3201 PF11447.3 EAU88530.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) ABC_tran PF00005.22 EAU88531.2 - 2.6e-21 76.3 0.0 4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 EAU88531.2 - 1.3e-06 28.0 0.0 3.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_21 PF13304.1 EAU88531.2 - 7.9e-06 26.0 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAU88531.2 - 9e-05 22.5 0.2 0.00013 22.0 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain UPF0079 PF02367.12 EAU88531.2 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EAU88531.2 - 0.00011 22.0 0.2 0.0016 18.3 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EAU88531.2 - 0.00018 21.1 0.1 0.001 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAU88531.2 - 0.00036 20.6 0.1 0.00099 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EAU88531.2 - 0.00041 19.6 0.0 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EAU88531.2 - 0.00083 19.0 0.1 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 EAU88531.2 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU88531.2 - 0.0023 18.3 0.0 0.0025 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAU88531.2 - 0.0023 17.6 0.3 0.019 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EAU88531.2 - 0.0026 16.9 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EAU88531.2 - 0.0033 16.8 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAU88531.2 - 0.013 14.3 0.1 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DnaB_C PF03796.10 EAU88531.2 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EAU88531.2 - 0.018 15.8 0.0 0.2 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EAU88531.2 - 0.022 14.2 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SE PF00437.15 EAU88531.2 - 0.029 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EAU88531.2 - 0.029 14.5 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HipA_N PF07805.7 EAU88531.2 - 0.048 13.8 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 HipA-like N-terminal domain PIF1 PF05970.9 EAU88531.2 - 0.063 12.2 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase PhoH PF02562.11 EAU88531.2 - 0.067 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PEPCK_ATP PF01293.15 EAU88531.2 - 0.073 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Arch_ATPase PF01637.13 EAU88531.2 - 0.077 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EAU88531.2 - 0.092 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EAU88531.2 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 EAU88531.2 - 0.12 12.0 0.2 0.28 10.8 0.0 1.7 2 0 0 2 2 1 0 NTPase PduV-EutP PF10662.4 EAU88531.2 - 0.15 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EAU88531.2 - 0.16 11.9 0.1 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EAU88531.2 - 0.17 10.3 0.0 3.4 6.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF2418 PF10332.4 EAU88533.2 - 4e-24 84.7 0.3 7.2e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) GAGA_bind PF06217.7 EAU88534.1 - 0.1 12.5 0.9 0.21 11.5 0.2 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family DUF3552 PF12072.3 EAU88534.1 - 0.26 10.4 7.3 0.15 11.2 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) tRNA-synt_2d PF01409.15 EAU88535.1 - 7e-49 166.2 0.5 4.3e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EAU88535.1 - 1.3e-24 86.1 0.1 2.6e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.14 EAU88536.1 - 2.3e-47 160.6 0.1 3e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 GrpE LRS4 PF10422.4 EAU88536.1 - 0.014 14.7 1.7 0.022 14.1 1.2 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 zf-C4pol PF14260.1 EAU88536.1 - 0.036 14.0 0.2 0.068 13.1 0.2 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta IncA PF04156.9 EAU88536.1 - 0.13 11.8 1.9 0.16 11.5 1.3 1.2 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 EAU88536.1 - 0.43 10.0 2.0 0.61 9.5 1.4 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PNGaseA PF12222.3 EAU88538.2 - 4.8e-40 137.7 0.1 2.6e-36 125.4 0.0 2.2 1 1 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF656 PF04920.7 EAU88538.2 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF656) Pmp3 PF01679.12 EAU88539.2 - 8.7e-17 60.5 3.3 1.2e-16 60.1 2.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SF3b1 PF08920.5 EAU88539.2 - 3.2 7.7 10.4 0.47 10.4 4.4 1.7 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 zf-H2C2_2 PF13465.1 EAU88540.2 - 2.6e-24 84.2 24.4 1.1e-07 31.7 0.0 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EAU88540.2 - 1.3e-18 66.1 31.2 7.4e-05 22.8 1.5 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU88540.2 - 2.4e-14 52.5 26.7 0.00051 20.1 2.0 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU88540.2 - 2.2e-05 24.4 8.2 0.33 11.1 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU88540.2 - 0.00049 20.2 8.4 0.24 11.6 0.1 4.0 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EAU88540.2 - 0.012 15.4 14.5 0.31 11.0 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Gag_p17 PF00540.13 EAU88540.2 - 0.082 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) zf-TRAF PF02176.13 EAU88540.2 - 0.49 10.8 14.5 0.077 13.3 1.7 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger CCAP PF11105.3 EAU88540.2 - 4.1 7.1 5.6 6.7 6.4 0.2 2.5 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a FBPase PF00316.15 EAU88541.1 - 2e-129 431.0 0.0 2.3e-129 430.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EAU88541.1 - 0.001 18.4 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family GCIP PF13324.1 EAU88543.1 - 6.1e-12 45.3 0.1 1.1e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Baculo_PEP_C PF04513.7 EAU88543.1 - 5.1 6.9 8.1 5.2 6.9 0.1 3.5 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M41 PF01434.13 EAU88544.2 - 8.5e-67 224.7 0.4 1.4e-66 224.0 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EAU88544.2 - 6.5e-44 149.3 0.1 4.2e-43 146.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU88544.2 - 1.7e-05 25.6 0.0 5.6e-05 23.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EAU88544.2 - 1.9e-05 24.7 2.1 0.0018 18.3 0.4 3.6 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EAU88544.2 - 4.3e-05 22.4 0.1 0.00056 18.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 EAU88544.2 - 5.4e-05 22.9 0.1 0.00026 20.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU88544.2 - 9.4e-05 22.5 1.4 0.0063 16.6 0.2 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAU88544.2 - 9.8e-05 21.4 0.2 0.00049 19.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAU88544.2 - 0.00015 21.3 0.8 0.00073 19.2 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EAU88544.2 - 0.0019 17.6 1.9 0.059 12.7 0.5 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EAU88544.2 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EAU88544.2 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAU88544.2 - 0.0039 17.1 0.9 0.0094 15.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EAU88544.2 - 0.0047 16.1 0.5 0.013 14.6 0.3 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EAU88544.2 - 0.0055 15.8 0.1 0.016 14.3 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EAU88544.2 - 0.006 16.4 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAU88544.2 - 0.012 15.2 0.2 0.16 11.6 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.9 EAU88544.2 - 0.018 14.9 0.0 0.061 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Beta_protein PF14350.1 EAU88544.2 - 0.022 13.9 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Beta protein AAA_18 PF13238.1 EAU88544.2 - 0.028 14.7 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EAU88544.2 - 0.038 12.9 0.0 0.081 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Glyco_transf_54 PF04666.8 EAU88544.2 - 0.059 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Sigma54_activ_2 PF14532.1 EAU88544.2 - 0.081 12.9 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EAU88544.2 - 0.085 12.3 0.6 0.34 10.3 0.1 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain DUF1227 PF06777.6 EAU88545.1 - 4.8e-59 198.2 0.2 1e-58 197.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EAU88545.1 - 4.4e-47 159.6 0.1 8.1e-47 158.8 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EAU88545.1 - 3e-45 154.1 0.0 5.9e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 EAU88545.1 - 0.00015 20.7 0.1 0.0018 17.0 0.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EAU88545.1 - 0.00063 19.2 0.1 0.44 10.0 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EAU88545.1 - 0.0095 15.7 0.0 0.36 10.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FBA_3 PF08268.7 EAU88545.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box associated domain Glucan_synthase PF02364.10 EAU88546.2 - 0 1360.3 0.0 0 1359.6 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EAU88546.2 - 1.4e-39 134.6 0.0 3.3e-39 133.3 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Mating_C PF12737.2 EAU88546.2 - 0.74 8.6 3.0 1.1 8.0 2.1 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 LRR_1 PF00560.28 EAU88547.2 - 0.0054 16.5 0.4 0.92 9.7 0.0 3.3 2 1 0 2 2 2 1 Leucine Rich Repeat LRR_6 PF13516.1 EAU88547.2 - 1.2 9.4 4.6 80 3.7 0.1 3.9 3 1 1 4 4 4 0 Leucine Rich repeat Cellulase PF00150.13 EAU88551.2 - 6.3e-15 55.1 0.3 1e-14 54.4 0.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EAU88551.2 - 0.00055 20.3 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EAU88551.2 - 0.0012 18.0 0.7 0.0075 15.4 0.0 2.3 3 0 0 3 3 3 1 Beta-galactosidase RAI16-like PF10257.4 EAU88552.2 - 3.4e-76 256.4 0.1 5.2e-76 255.8 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Nucleoplasmin PF03066.10 EAU88552.2 - 0.012 15.1 1.8 0.031 13.7 1.2 1.7 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EAU88552.2 - 0.3 11.3 9.5 0.11 12.7 3.4 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DnaJ PF00226.26 EAU88553.2 - 8.4e-21 73.4 2.0 8.4e-21 73.4 1.4 2.1 2 0 0 2 2 2 1 DnaJ domain PAP2 PF01569.16 EAU88553.2 - 1.4e-13 50.6 2.6 3e-13 49.5 1.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 EAU88553.2 - 0.039 13.6 1.0 0.084 12.6 0.2 1.8 2 0 0 2 2 2 0 Divergent PAP2 family Rubis-subs-bind PF09273.6 EAU88556.2 - 3e-05 23.9 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EAU88556.2 - 0.0045 17.3 0.1 0.013 15.8 0.1 1.7 1 1 0 1 1 1 1 SET domain adh_short PF00106.20 EAU88557.1 - 5.6e-33 114.2 2.0 7.3e-33 113.8 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU88557.1 - 3e-13 50.1 0.1 4e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU88557.1 - 8.8e-13 48.3 0.4 1.1e-12 47.9 0.3 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAU88557.1 - 4e-05 23.3 0.8 9.4e-05 22.1 0.6 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EAU88557.1 - 0.003 16.5 0.1 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EAU88557.1 - 0.0047 16.3 0.2 0.0078 15.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EAU88557.1 - 0.0054 15.9 0.0 0.0073 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 EAU88557.1 - 0.0067 16.1 0.3 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Helicase_RecD PF05127.9 EAU88557.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase THF_DHG_CYH_C PF02882.14 EAU88557.1 - 0.021 13.8 0.1 0.056 12.5 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EAU88557.1 - 0.023 14.6 2.1 0.17 11.8 1.4 2.2 1 1 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EAU88557.1 - 0.13 12.3 0.2 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_15 PF01793.11 EAU88559.2 - 4.1e-110 367.8 3.8 7.9e-110 366.8 2.6 1.4 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Abhydrolase_6 PF12697.2 EAU88560.2 - 0.007 16.2 0.0 0.34 10.7 0.0 2.4 2 1 1 3 3 3 2 Alpha/beta hydrolase family RWD PF05773.17 EAU88561.2 - 9.6e-19 67.3 1.0 9.6e-19 67.3 0.7 1.7 2 0 0 2 2 2 1 RWD domain FtsL PF04999.8 EAU88561.2 - 0.031 13.9 0.4 0.077 12.7 0.3 1.7 1 0 0 1 1 1 0 Cell division protein FtsL RimK PF08443.6 EAU88561.2 - 0.036 13.5 0.1 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Ribosomal_S21 PF01165.15 EAU88562.2 - 2.2e-11 43.0 5.4 3.9e-11 42.2 3.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Fer2_4 PF13510.1 EAU88562.2 - 0.0026 17.5 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Cyclin_N PF00134.18 EAU88564.2 - 5.7e-16 58.2 0.2 1e-14 54.2 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAU88564.2 - 7e-07 29.1 0.2 0.019 14.8 0.0 2.6 2 1 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 EAU88564.2 - 3e-05 23.7 0.1 0.00044 20.0 0.0 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat IF-2B PF01008.12 EAU88565.2 - 5.9e-61 205.9 0.0 9.6e-61 205.2 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M24 PF00557.19 EAU88567.1 - 9.4e-48 162.5 0.0 1.1e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 Acyltransferase PF01553.16 EAU88568.2 - 5.3e-13 48.5 0.0 2e-11 43.4 0.0 2.7 2 1 0 2 2 2 1 Acyltransferase NOC3p PF07540.6 EAU88570.2 - 7.4e-27 93.4 1.6 1.6e-26 92.3 0.0 2.5 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EAU88570.2 - 1.2e-23 83.3 1.2 5.5e-23 81.2 0.0 2.4 2 1 0 2 2 2 1 CBF/Mak21 family AAA_11 PF13086.1 EAU88570.2 - 0.00083 18.9 4.3 0.0014 18.2 3.0 1.3 1 0 0 1 1 1 1 AAA domain TEA PF01285.13 EAU88571.1 - 6.1e-10 38.8 5.9 8.4e-10 38.3 2.8 2.2 1 1 1 2 2 2 1 TEA/ATTS domain family UEV PF05743.8 EAU88572.2 - 7.8e-35 119.1 0.0 1.3e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EAU88572.2 - 6.3e-28 96.1 0.3 6.3e-28 96.1 0.2 1.8 2 0 0 2 2 2 1 Vps23 core domain RWD PF05773.17 EAU88572.2 - 0.13 12.1 0.9 2 8.3 0.0 2.5 2 0 0 2 2 2 0 RWD domain MSC PF09402.5 EAU88573.2 - 3.2e-54 183.8 0.1 9.8e-54 182.2 0.0 1.8 2 1 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EAU88573.2 - 2e-11 43.2 0.0 4.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain Pyr_redox_2 PF07992.9 EAU88574.1 - 2.1e-07 31.0 0.0 0.004 17.0 0.0 3.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EAU88574.1 - 0.00012 21.7 0.1 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain NAD_binding_9 PF13454.1 EAU88574.1 - 0.0065 16.2 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EAU88574.1 - 0.034 14.2 0.1 1.4 8.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 EAU88574.1 - 0.054 12.5 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) DAO PF01266.19 EAU88574.1 - 0.092 11.6 0.1 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EAU88574.1 - 0.13 11.0 0.1 9.9 4.8 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Cu_bind_like PF02298.12 EAU88576.2 - 0.00011 21.9 1.5 0.00012 21.8 0.1 1.7 2 0 0 2 2 2 1 Plastocyanin-like domain Adaptin_N PF01602.15 EAU88578.2 - 2.8e-127 425.2 3.0 3.8e-127 424.7 2.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EAU88578.2 - 6e-27 94.6 0.2 2.1e-25 89.5 0.0 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EAU88578.2 - 1.8e-18 66.5 9.0 9.9e-09 35.3 0.2 4.9 3 1 1 4 4 4 4 HEAT repeats HEAT PF02985.17 EAU88578.2 - 2.9e-08 33.1 6.5 0.015 15.3 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EAU88578.2 - 0.0001 22.6 3.5 4.3 7.9 0.1 5.9 4 2 3 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EAU88578.2 - 0.0013 18.0 0.0 0.037 13.3 0.0 2.4 2 0 0 2 2 2 1 CLASP N terminal Arm PF00514.18 EAU88578.2 - 0.0018 17.9 0.1 1.3 8.9 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EAU88578.2 - 0.043 12.7 0.1 0.29 10.0 0.0 2.1 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain OTU PF02338.14 EAU88579.1 - 6e-17 62.3 0.0 5.1e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EAU88579.1 - 1.8e-05 24.2 0.0 0.14 11.4 0.0 2.8 1 1 2 3 3 3 2 Peptidase C65 Otubain DUF1878 PF08963.5 EAU88579.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) ECH PF00378.15 EAU88581.1 - 1.9e-25 89.3 0.0 3.1e-25 88.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AA_permease PF00324.16 EAU88582.2 - 4.4e-119 397.9 40.1 5.3e-119 397.6 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAU88582.2 - 5.2e-28 97.7 48.0 1e-27 96.8 32.5 1.7 1 1 0 1 1 1 1 Amino acid permease Pirin PF02678.11 EAU88583.1 - 1.4e-31 108.4 0.4 5.6e-31 106.5 0.1 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EAU88583.1 - 2.3e-26 91.8 0.1 6.8e-26 90.3 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain PQQ_2 PF13360.1 EAU88584.2 - 0.0071 15.8 0.7 0.37 10.2 0.0 2.4 1 1 2 3 3 3 3 PQQ-like domain CLTH PF10607.4 EAU88585.1 - 9e-22 77.3 0.0 2.2e-21 76.0 0.0 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EAU88585.1 - 2.6e-16 59.0 0.9 2.6e-16 59.0 0.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EAU88585.1 - 0.0046 16.9 0.2 0.0083 16.1 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EAU88585.1 - 0.0052 16.0 1.0 0.022 13.9 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger Borrelia_P83 PF05262.6 EAU88585.1 - 0.011 13.9 0.7 0.016 13.5 0.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-RING_5 PF14634.1 EAU88585.1 - 0.02 14.6 0.4 0.04 13.6 0.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU88585.1 - 0.022 14.4 0.9 0.039 13.6 0.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU88585.1 - 0.023 14.5 0.4 0.04 13.7 0.3 1.4 1 0 0 1 1 1 0 Ring finger domain Gp58 PF07902.6 EAU88585.1 - 0.028 12.6 0.1 0.034 12.3 0.1 1.1 1 0 0 1 1 1 0 gp58-like protein WXG100 PF06013.7 EAU88585.1 - 0.077 13.0 2.7 0.79 9.7 0.0 2.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG zf-C3HC4_3 PF13920.1 EAU88585.1 - 0.12 12.0 0.3 0.2 11.3 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EAU88585.1 - 0.14 11.7 0.5 0.25 10.8 0.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RabGAP-TBC PF00566.13 EAU88586.1 - 2.3e-27 95.8 0.1 5.4e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain G-patch PF01585.18 EAU88587.2 - 1.4e-08 34.4 4.0 3e-08 33.3 2.8 1.6 1 0 0 1 1 1 1 G-patch domain TFIIA PF03153.8 EAU88587.2 - 8.8 6.1 18.1 0.67 9.7 6.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CsbD PF05532.7 EAU88588.1 - 0.0012 18.4 1.4 0.0012 18.4 1.0 1.7 2 0 0 2 2 2 1 CsbD-like Auts2 PF15336.1 EAU88588.1 - 0.057 13.4 0.8 0.067 13.2 0.6 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Oligomerisation PF02410.10 EAU88589.1 - 3.2e-06 27.1 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Oligomerisation domain SHR3_chaperone PF08229.6 EAU88590.2 - 3.4e-25 88.1 0.0 4.3e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 EAU88590.2 - 0.0084 16.4 0.1 0.24 11.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) DUF2917 PF11142.3 EAU88590.2 - 0.076 12.2 0.2 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) LETM1 PF07766.8 EAU88591.2 - 2.9e-100 334.7 0.9 2.9e-100 334.7 0.6 1.5 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 EAU88591.2 - 0.00035 20.6 0.0 0.058 13.5 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair SAP PF02037.22 EAU88591.2 - 0.0028 17.0 0.1 0.014 14.8 0.0 2.3 2 0 0 2 2 2 1 SAP domain DUF2360 PF10152.4 EAU88591.2 - 0.0038 17.5 2.6 0.0056 16.9 0.5 2.1 2 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) EF-hand_1 PF00036.27 EAU88591.2 - 0.0043 16.2 0.0 0.31 10.4 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 EAU88591.2 - 0.033 14.0 1.1 19 5.4 0.0 4.1 4 0 0 4 4 4 0 EF-hand domain EF-hand_8 PF13833.1 EAU88591.2 - 0.1 12.2 0.0 0.46 10.1 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair Syntaxin-6_N PF09177.6 EAU88591.2 - 1.6 9.2 4.5 5 7.5 0.7 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DcpS_C PF11969.3 EAU88593.2 - 2.1e-14 53.7 0.1 4.9e-14 52.5 0.1 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EAU88593.2 - 4e-10 40.1 0.2 1.3e-08 35.2 0.1 2.4 1 1 0 1 1 1 1 HIT domain ROS_MUCR PF05443.6 EAU88593.2 - 0.024 14.3 0.9 0.035 13.8 0.0 1.7 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF678 PF05077.7 EAU88593.2 - 0.029 14.3 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF678) PhoU PF01895.14 EAU88593.2 - 0.091 13.2 0.2 0.55 10.7 0.1 2.0 2 0 0 2 2 2 0 PhoU domain ox_reductase_C PF08635.5 EAU88594.2 - 4.7e-73 243.2 0.3 6.5e-73 242.8 0.2 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EAU88594.2 - 7.5e-22 78.0 0.0 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAU88594.2 - 0.013 15.2 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF869 PF05911.6 EAU88595.1 - 0.0017 16.7 1.9 0.0024 16.2 1.3 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF730 PF05325.6 EAU88595.1 - 0.0042 16.8 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF730) DUF972 PF06156.8 EAU88595.1 - 0.017 15.4 3.2 0.032 14.5 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EAU88595.1 - 0.036 14.3 4.6 0.036 14.3 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EAU88595.1 - 0.18 9.6 1.5 0.17 9.6 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipoprotein_20 PF13942.1 EAU88595.1 - 0.2 11.1 5.1 0.27 10.7 3.5 1.2 1 0 0 1 1 1 0 YfhG lipoprotein APG6 PF04111.7 EAU88595.1 - 0.21 10.5 3.6 0.3 10.0 2.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 EAU88595.1 - 0.24 11.3 4.2 0.26 11.1 2.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 EAU88595.1 - 0.25 11.3 7.9 0.16 12.0 4.2 1.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.11 EAU88595.1 - 0.27 11.4 3.7 0.16 12.2 1.5 1.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 Matrilin_ccoil PF10393.4 EAU88595.1 - 0.41 10.0 4.5 0.34 10.3 1.2 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin SlyX PF04102.7 EAU88595.1 - 0.62 10.4 5.0 0.43 10.9 1.7 2.0 2 0 0 2 2 2 0 SlyX DivIC PF04977.10 EAU88595.1 - 0.66 9.5 3.8 1.3 8.5 2.7 1.5 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EAU88595.1 - 1.1 8.9 6.3 0.15 11.8 1.3 1.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Uds1 PF15456.1 EAU88595.1 - 1.4 8.9 10.6 1.1 9.2 3.3 2.2 2 0 0 2 2 2 0 Up-regulated During Septation IncA PF04156.9 EAU88595.1 - 5 6.6 10.5 0.91 9.0 4.9 1.5 2 0 0 2 2 2 0 IncA protein DUF4140 PF13600.1 EAU88595.1 - 6 7.3 7.8 0.98 9.9 2.8 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PIG-Y PF15159.1 EAU88596.1 - 2.3e-08 34.1 2.6 2.8e-08 33.8 1.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Sfi1 PF08457.5 EAU88597.2 - 2.4e-27 95.5 112.9 1.3e-16 60.1 25.0 4.8 1 1 3 4 4 4 4 Sfi1 spindle body protein Fungal_trans PF04082.13 EAU88598.2 - 1.4e-11 43.7 0.1 2.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU88598.2 - 0.0088 15.9 14.9 0.018 14.9 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-bind PF00127.15 EAU88599.2 - 8.1e-05 22.7 0.1 0.0071 16.5 0.0 2.7 2 1 0 2 2 2 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EAU88599.2 - 0.00033 20.4 0.0 0.13 12.1 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain Cu_bind_like PF02298.12 EAU88599.2 - 0.098 12.4 3.2 0.15 11.8 0.3 2.7 2 2 0 2 2 2 0 Plastocyanin-like domain Rhodanese PF00581.15 EAU88599.2 - 0.11 12.9 0.0 8.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Rhodanese-like domain MUG113 PF13455.1 EAU88600.2 - 1.6e-19 70.1 2.3 2.2e-16 60.0 0.0 3.2 3 0 0 3 3 3 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EAU88600.2 - 1.4e-12 47.8 1.0 1.6e-10 41.2 0.4 3.2 2 1 0 2 2 2 1 T5orf172 domain zf-primase PF09329.6 EAU88600.2 - 0.063 12.8 0.8 0.16 11.6 0.5 1.6 1 0 0 1 1 1 0 Primase zinc finger PAT1 PF09770.4 EAU88600.2 - 0.26 9.4 14.2 0.33 9.1 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ORC6 PF05460.8 EAU88600.2 - 3 6.8 13.6 6.3 5.7 9.4 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sas10_Utp3 PF04000.10 EAU88601.2 - 1.6e-06 28.2 0.2 3.4e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Ist1 PF03398.9 EAU88603.2 - 3.6e-30 104.5 0.0 6.8e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 EAU88603.2 - 2.1e-11 43.7 0.1 5.6e-09 35.7 0.0 3.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1697 PF08002.6 EAU88603.2 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) PIG-H PF10181.4 EAU88604.2 - 4.7e-13 48.5 0.0 7.3e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component MscS_TM PF12794.2 EAU88604.2 - 0.063 11.8 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Far-17a_AIG1 PF04750.9 EAU88605.2 - 4.6e-40 136.9 1.1 5.5e-40 136.6 0.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pept_tRNA_hydro PF01195.14 EAU88606.2 - 3.4e-24 85.3 0.0 4.7e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Nodulin-like PF06813.8 EAU88607.2 - 0.00057 19.2 6.7 0.00057 19.2 4.6 1.8 2 0 0 2 2 2 1 Nodulin-like Lyase_1 PF00206.15 EAU88608.1 - 2.3e-93 312.8 0.0 3.5e-93 312.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EAU88608.1 - 1.8e-28 98.3 0.1 3.7e-28 97.3 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SNARE PF05739.14 EAU88609.2 - 5e-15 54.9 2.8 5e-15 54.9 1.9 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EAU88609.2 - 4.5e-13 49.2 0.4 4.5e-13 49.2 0.3 3.2 4 0 0 4 4 4 1 Syntaxin MCPsignal PF00015.16 EAU88609.2 - 0.00093 18.8 12.7 0.0031 17.0 4.6 2.2 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EAU88609.2 - 0.005 16.4 4.0 0.019 14.5 0.4 2.5 2 0 0 2 2 2 1 Synaptobrevin Trep_Strep PF09605.5 EAU88609.2 - 0.0098 15.5 0.2 0.017 14.7 0.2 1.3 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Herpes_US9 PF06072.6 EAU88609.2 - 0.025 14.3 0.1 0.066 13.0 0.1 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Spectrin PF00435.16 EAU88609.2 - 0.028 14.7 5.1 1.7 8.9 0.0 3.2 3 1 0 3 3 3 0 Spectrin repeat VitD-bind_III PF09164.5 EAU88609.2 - 0.069 12.7 0.6 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Vitamin D binding protein, domain III ACC_epsilon PF13822.1 EAU88609.2 - 0.1 12.9 2.0 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ycf34 PF10718.4 EAU88609.2 - 0.15 12.4 0.2 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 Syntaxin_2 PF14523.1 EAU88609.2 - 0.34 10.9 13.4 0.022 14.8 2.5 2.8 2 1 1 3 3 3 0 Syntaxin-like protein DUF4094 PF13334.1 EAU88609.2 - 0.37 11.1 5.9 0.5 10.7 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.4 EAU88609.2 - 0.6 10.2 7.0 3.8 7.7 1.6 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 EAU88609.2 - 0.68 9.7 4.2 1.2 8.9 0.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EAU88609.2 - 1.1 9.5 5.0 7.9 6.8 1.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein T4SS PF07996.6 EAU88609.2 - 1.3 8.8 19.0 0.053 13.3 7.8 2.2 2 1 0 2 2 2 0 Type IV secretion system proteins Fib_alpha PF08702.5 EAU88609.2 - 1.6 8.8 7.3 0.3 11.1 0.3 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.10 EAU88609.2 - 1.7 8.8 12.9 0.35 11.0 1.2 3.6 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3708 PF12501.3 EAU88609.2 - 1.9 8.2 10.7 1.7 8.4 1.0 3.0 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter WXG100 PF06013.7 EAU88609.2 - 4.4 7.3 12.8 2.1 8.4 0.0 4.1 2 2 1 3 3 3 0 Proteins of 100 residues with WXG zf-AN1 PF01428.11 EAU88610.1 - 1.1e-08 34.8 13.7 3.2e-08 33.3 9.5 1.8 1 1 0 1 1 1 1 AN1-like Zinc finger Integrase_Zn PF02022.14 EAU88610.1 - 0.063 12.7 0.1 0.063 12.7 0.1 2.4 3 0 0 3 3 3 0 Integrase Zinc binding domain Peptidase_C7 PF01830.13 EAU88610.1 - 0.24 10.5 1.9 0.27 10.3 1.3 1.1 1 0 0 1 1 1 0 Peptidase C7 family DUF1272 PF06906.6 EAU88610.1 - 1.1 9.1 6.9 6.8 6.6 0.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1272) IBR PF01485.16 EAU88610.1 - 2 8.3 8.9 3.1 7.7 6.0 1.5 1 1 0 1 1 1 0 IBR domain Aminotran_1_2 PF00155.16 EAU88611.2 - 6.2e-90 301.7 0.0 7e-90 301.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.17 EAU88612.2 - 3.8e-17 60.7 13.7 0.031 14.3 0.1 10.1 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.1 EAU88612.2 - 2.3e-16 59.8 6.8 0.0012 19.1 0.0 6.7 4 3 3 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 EAU88612.2 - 9.2e-06 25.9 17.4 0.00027 21.3 0.5 7.6 9 0 0 9 9 9 1 HEAT-like repeat TPD52 PF04201.10 EAU88616.2 - 0.0076 15.9 2.4 0.011 15.4 1.6 1.2 1 0 0 1 1 1 1 Tumour protein D52 family PEARLI-4 PF05278.7 EAU88616.2 - 0.013 14.9 2.1 0.019 14.3 1.5 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) GAS PF13851.1 EAU88616.2 - 0.034 13.3 0.3 0.047 12.8 0.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.15 EAU88616.2 - 0.04 12.9 3.9 0.059 12.4 2.7 1.1 1 0 0 1 1 1 0 Tropomyosin Laminin_II PF06009.7 EAU88616.2 - 0.077 12.7 1.0 0.11 12.2 0.7 1.2 1 0 0 1 1 1 0 Laminin Domain II Bap31 PF05529.7 EAU88616.2 - 0.077 12.4 3.3 0.084 12.3 0.9 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Sugarporin_N PF11471.3 EAU88616.2 - 0.35 10.5 10.0 0.16 11.6 3.9 2.7 3 1 0 3 3 3 0 Maltoporin periplasmic N-terminal extension FUN14 PF04930.10 EAU88618.1 - 1.2e-19 70.3 0.1 1.9e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 FUN14 family Peptidase_S8 PF00082.17 EAU88620.2 - 7.5e-53 179.5 1.5 1.3e-52 178.7 1.0 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EAU88620.2 - 5e-28 96.7 0.2 9.1e-28 95.8 0.1 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain TRM PF02005.11 EAU88621.2 - 1.3e-121 406.0 0.0 1.7e-121 405.7 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EAU88621.2 - 0.00019 21.1 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EAU88621.2 - 0.0033 17.4 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 EAU88622.2 - 7.8e-69 231.7 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88622.2 - 5.3e-47 160.0 0.0 8.1e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EAU88622.2 - 9.6e-23 80.1 0.0 1.9e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EAU88622.2 - 1.3e-11 44.4 0.1 2.6e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EAU88622.2 - 2.6e-11 43.2 0.1 5e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EAU88622.2 - 7.2e-05 21.8 0.0 0.00056 18.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FeoA PF04023.9 EAU88622.2 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 FeoA domain Seadorna_VP7 PF07387.6 EAU88622.2 - 0.34 9.6 0.0 0.6 8.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_60s PF00428.14 EAU88622.2 - 3.5 8.0 20.5 12 6.3 2.5 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Alpha-amylase PF00128.19 EAU88623.2 - 8.7e-21 74.6 3.3 2e-17 63.5 1.7 3.2 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EAU88623.2 - 3.8e-16 59.3 0.0 7.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EAU88623.2 - 1.6e-08 34.7 0.0 6.8e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EAU88623.2 - 2.8e-08 33.3 0.0 5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 VGCC_beta4Aa_N PF12052.3 EAU88623.2 - 0.61 9.9 1.1 2.3 8.1 0.8 2.0 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF2040 PF09745.4 EAU88624.2 - 6.5e-36 122.9 22.8 6.5e-36 122.9 15.8 3.3 2 2 2 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) TFIID-18kDa PF02269.11 EAU88625.2 - 7.1e-21 73.8 1.0 7.8e-21 73.6 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit PAT1 PF09770.4 EAU88625.2 - 6.1 4.9 9.7 7.1 4.7 6.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4211 PF13926.1 EAU88626.1 - 7.9e-37 126.0 0.0 7.9e-37 126.0 0.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4211) C1_1 PF00130.17 EAU88627.2 - 4.5e-08 32.6 13.6 1.1e-07 31.4 1.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.1 EAU88627.2 - 0.00024 19.6 0.3 0.00047 18.6 0.2 1.4 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 PHD PF00628.24 EAU88627.2 - 0.0036 16.9 12.2 0.076 12.7 1.1 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 EAU88627.2 - 0.41 10.0 4.4 8.4 5.7 0.3 2.7 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EAU88627.2 - 0.73 9.6 11.2 0.51 10.1 0.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 TRAPPC9-Trs120 PF08626.6 EAU88629.2 - 4e-80 269.5 0.0 1.9e-62 211.0 0.0 3.6 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Vps55 PF04133.9 EAU88630.1 - 2.5e-42 143.3 5.2 2.8e-42 143.2 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 BCLP PF12304.3 EAU88630.1 - 0.083 12.2 2.2 0.13 11.6 1.4 1.5 1 1 1 2 2 2 0 Beta-casein like protein Herpes_LMP1 PF05297.6 EAU88630.1 - 0.23 10.3 1.5 0.3 9.9 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Wzy_C PF04932.10 EAU88630.1 - 2.8 7.7 6.2 3.6 7.3 4.3 1.5 1 1 0 1 1 1 0 O-Antigen ligase Chromo PF00385.19 EAU88631.2 - 8.6e-10 38.1 5.2 1.6e-09 37.2 3.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.9 EAU88633.2 - 4.6e-09 35.7 0.0 1.1e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 EAU88633.2 - 0.19 11.4 1.4 0.27 11.0 0.1 2.0 2 1 0 2 2 2 0 BED zinc finger Inhibitor_I71 PF12628.2 EAU88634.2 - 0.12 12.0 0.1 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor FtsX PF02687.16 EAU88635.2 - 0.042 13.6 2.8 0.064 13.0 0.3 2.0 2 0 0 2 2 2 0 FtsX-like permease family GtrA PF04138.9 EAU88635.2 - 0.055 13.4 4.1 0.043 13.7 1.4 1.8 1 1 1 2 2 2 0 GtrA-like protein mRNA_cap_enzyme PF01331.14 EAU88637.1 - 2.1e-48 164.5 0.1 3e-48 164.0 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EAU88637.1 - 5.3e-17 62.0 0.1 1.3e-16 60.8 0.1 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EAU88637.1 - 8e-08 31.8 0.0 1.9e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Skp1 PF01466.14 EAU88638.2 - 1.1e-39 134.3 1.5 1.6e-39 133.7 1.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EAU88638.2 - 1.8e-23 82.3 0.1 5.6e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EAU88638.2 - 0.00075 19.4 0.0 0.059 13.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF615 PF04751.9 EAU88638.2 - 0.026 14.1 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Ribosomal_L27 PF01016.14 EAU88639.2 - 1.9e-30 104.4 0.3 2.5e-30 104.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein PhyH PF05721.8 EAU88639.2 - 0.098 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) F-box-like PF12937.2 EAU88641.1 - 0.0003 20.4 0.5 0.0015 18.2 0.4 2.2 1 1 0 1 1 1 1 F-box-like DUF1456 PF07308.8 EAU88641.1 - 0.0076 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1456) LRR_4 PF12799.2 EAU88641.1 - 0.24 11.0 9.0 37 4.1 0.6 5.1 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EAU88641.1 - 0.6 10.5 13.4 11 6.6 0.2 5.5 6 0 0 6 6 6 0 Leucine rich repeat F-box-like PF12937.2 EAU88642.1 - 7.6e-09 35.1 0.6 2.1e-08 33.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU88642.1 - 0.034 13.8 0.5 4.3 7.1 0.0 2.8 2 0 0 2 2 2 0 F-box domain FAM101 PF15068.1 EAU88642.1 - 0.071 12.5 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 FAM101 family DUF1183 PF06682.7 EAU88643.2 - 3.6 7.0 6.5 1.3 8.5 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1183) Lipase_3 PF01764.20 EAU88644.1 - 2.1e-07 30.6 0.0 4.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EAU88644.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU88644.1 - 0.016 15.1 0.6 0.034 14.0 0.4 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EAU88644.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EAU88644.1 - 0.24 10.9 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Amidohydro_1 PF01979.15 EAU88645.1 - 2.3e-34 119.5 0.0 4.2e-34 118.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EAU88645.1 - 6.1e-08 32.3 0.1 0.00047 19.4 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EAU88645.1 - 1.4e-06 28.0 0.0 3.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EAU88645.1 - 0.00017 21.6 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 EAU88645.1 - 0.12 11.3 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Methyltransf_31 PF13847.1 EAU88648.2 - 9.7e-29 99.9 0.0 1.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU88648.2 - 4.9e-20 71.8 0.0 9.4e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU88648.2 - 2.6e-16 60.1 0.0 6.6e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU88648.2 - 2.3e-14 53.5 0.0 8.9e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU88648.2 - 1.8e-13 50.1 0.0 4e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EAU88648.2 - 6.1e-12 45.5 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU88648.2 - 5.8e-11 42.4 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU88648.2 - 1e-10 41.9 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU88648.2 - 2.7e-08 33.3 0.0 4.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EAU88648.2 - 7.4e-08 31.8 0.1 1.2e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EAU88648.2 - 2.8e-07 30.2 0.0 1.8e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Rhodanese PF00581.15 EAU88648.2 - 7.2e-07 29.5 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_8 PF05148.10 EAU88648.2 - 0.0002 21.0 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EAU88648.2 - 0.00024 21.9 0.0 0.41 11.4 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EAU88648.2 - 0.00063 18.9 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 EAU88648.2 - 0.0027 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) UPF0020 PF01170.13 EAU88648.2 - 0.048 13.2 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_29 PF03141.11 EAU88648.2 - 0.12 10.6 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 EAU88648.2 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.7 EAU88648.2 - 0.16 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW POP1 PF06978.6 EAU88649.1 - 0.0036 16.9 2.2 0.0082 15.8 1.5 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 Pap_E4 PF02711.9 EAU88649.1 - 6.8 7.5 12.0 59 4.5 7.0 2.9 2 1 0 2 2 2 0 E4 protein Transposase_21 PF02992.9 EAU88650.2 - 6.2e-10 38.5 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Spt4 PF06093.8 EAU88651.2 - 0.12 12.2 0.2 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Herpes_capsid PF06112.6 EAU88651.2 - 0.96 9.4 9.2 1.6 8.7 6.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ORC6 PF05460.8 EAU88651.2 - 1.3 8.0 4.9 1.7 7.6 3.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAP1 PF07218.6 EAU88651.2 - 9.1 4.2 6.0 12 3.8 4.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2277 PF10041.4 EAU88653.2 - 0.075 13.0 0.4 0.41 10.6 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) CHORD PF04968.7 EAU88653.2 - 0.65 10.2 14.3 1.4 9.2 9.9 1.5 1 0 0 1 1 1 0 CHORD Baculo_PEP_C PF04513.7 EAU88653.2 - 10 5.9 6.9 26 4.6 0.2 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phosducin PF02114.11 EAU88654.2 - 6.3e-21 74.2 0.2 9.6e-08 31.0 0.0 3.2 2 1 1 3 3 3 3 Phosducin peroxidase PF00141.18 EAU88655.2 - 5.9e-22 78.2 0.0 9.7e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4537 PF15057.1 EAU88657.1 - 0.00086 19.0 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PWWP PF00855.12 EAU88657.1 - 0.0055 16.8 0.1 1.6 8.9 0.0 3.0 2 0 0 2 2 2 2 PWWP domain Mnd1 PF03962.10 EAU88657.1 - 2.4 7.7 9.4 0.12 12.0 1.9 2.2 2 0 0 2 2 2 0 Mnd1 family GDA1_CD39 PF01150.12 EAU88658.1 - 1.5e-95 320.2 0.0 2.3e-88 296.6 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family AA_permease PF00324.16 EAU88661.1 - 1.4e-96 323.7 29.8 1.4e-96 323.7 20.7 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAU88661.1 - 2.8e-16 59.1 39.3 3.7e-16 58.7 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease AIG2 PF06094.7 EAU88663.2 - 4.1e-07 30.4 0.0 5.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 EAU88663.2 - 8.6e-05 22.5 0.1 0.00012 22.0 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family Imm10 PF15562.1 EAU88663.2 - 0.068 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 10 TrmE_N PF10396.4 EAU88664.2 - 2.5e-35 120.8 0.0 4.8e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EAU88664.2 - 5.4e-21 74.7 0.0 1.6e-20 73.2 0.0 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EAU88664.2 - 3.4e-18 65.7 0.0 6.6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU88664.2 - 4.8e-05 23.2 0.0 0.00016 21.5 0.0 1.9 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 EAU88664.2 - 0.00067 20.1 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EAU88664.2 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EAU88664.2 - 0.001 19.8 0.1 0.0053 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAU88664.2 - 0.0018 18.2 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EAU88664.2 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 EAU88664.2 - 0.019 14.3 0.0 0.77 9.1 0.0 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ALF PF03752.8 EAU88664.2 - 0.036 13.9 0.1 0.24 11.3 0.1 2.4 2 0 0 2 2 2 0 Short repeats of unknown function AAA_18 PF13238.1 EAU88664.2 - 0.098 12.9 0.0 0.28 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAU88664.2 - 0.14 12.2 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ribosomal_L7Ae PF01248.21 EAU88665.1 - 1.5e-25 88.5 0.1 1.9e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EAU88665.1 - 0.00033 20.5 0.0 0.00037 20.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EAU88665.1 - 0.019 14.7 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Mannosyl_trans PF05007.8 EAU88666.1 - 4e-77 259.3 12.1 5.7e-77 258.8 8.4 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EAU88666.1 - 1.4e-16 60.3 3.0 1.4e-16 60.3 2.1 2.3 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EAU88666.1 - 0.2 11.1 23.5 0.0087 15.5 9.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) Arf PF00025.16 EAU88667.1 - 4.6e-68 227.8 0.0 5.2e-68 227.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EAU88667.1 - 1.4e-11 43.7 0.2 5.1e-08 32.0 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EAU88667.1 - 6.8e-10 38.4 0.0 8.8e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EAU88667.1 - 9.7e-08 32.5 0.0 1.4e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAU88667.1 - 2.5e-07 30.6 0.0 7.8e-07 29.0 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EAU88667.1 - 2.6e-06 26.9 0.0 3.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EAU88667.1 - 4e-05 22.8 0.0 4.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAU88667.1 - 0.00047 19.6 0.0 0.012 15.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EAU88667.1 - 0.018 14.5 0.0 0.051 13.0 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EAU88667.1 - 0.047 13.8 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain CDRT4 PF15213.1 EAU88668.1 - 0.053 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein ATG16 PF08614.6 EAU88668.1 - 0.073 12.8 15.2 0.19 11.5 9.4 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EAU88668.1 - 0.36 9.8 13.2 0.59 9.1 9.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EAU88668.1 - 0.57 7.9 11.3 0.71 7.6 7.0 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 EAU88668.1 - 8.7 6.1 8.1 18 5.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) PAP2 PF01569.16 EAU88669.2 - 0.022 14.4 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 PAP2 superfamily Cofilin_ADF PF00241.15 EAU88672.2 - 5.6e-09 35.9 0.0 6.2e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ArfGap PF01412.13 EAU88673.2 - 0.013 15.2 0.2 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf LIM PF00412.17 EAU88673.2 - 0.2 11.7 2.6 0.27 11.3 0.4 1.9 2 0 0 2 2 2 0 LIM domain DZR PF12773.2 EAU88673.2 - 0.31 10.8 2.4 3.8 7.4 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon Fungal_trans PF04082.13 EAU88675.2 - 6e-26 90.8 0.5 7.1e-25 87.3 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU88675.2 - 8.3e-10 38.4 4.4 1.7e-09 37.3 3.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_17 PF00332.13 EAU88679.2 - 1.3e-10 40.8 0.1 1.8e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 DUF4434 PF14488.1 EAU88679.2 - 0.18 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Pro_isomerase PF00160.16 EAU88681.2 - 3.6e-49 166.9 0.0 4e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EAU88682.2 - 1.6e-49 164.1 25.1 2.8e-08 33.3 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EAU88682.2 - 2.3e-13 49.6 1.2 6.3e-13 48.2 0.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU88682.2 - 2.6e-11 42.8 0.7 6.6e-11 41.5 0.5 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EAU88682.2 - 2.5e-05 22.6 8.1 0.15 10.1 0.0 5.0 4 2 2 6 6 6 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EAU88682.2 - 0.0016 17.9 4.8 0.56 9.6 0.2 3.4 2 2 1 3 3 3 3 PQQ-like domain Arylsulfotran_2 PF14269.1 EAU88682.2 - 0.16 11.0 1.9 0.36 9.9 0.0 2.4 4 0 0 4 4 4 0 Arylsulfotransferase (ASST) Fungal_trans PF04082.13 EAU88683.2 - 8.4e-21 74.0 1.4 2.1e-20 72.7 1.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU88683.2 - 4.9e-06 26.3 7.5 1e-05 25.3 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neisseria_TspB PF05616.8 EAU88684.2 - 0.038 12.3 0.5 0.051 11.9 0.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4283 PF14111.1 EAU88685.2 - 0.014 14.4 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) CTP_transf_2 PF01467.21 EAU88686.2 - 8.8e-11 42.0 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Nuc_sug_transp PF04142.10 EAU88687.1 - 1.2e-77 260.3 7.9 1.9e-77 259.6 5.5 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EAU88687.1 - 3.6e-09 35.9 7.6 6.3e-09 35.1 5.2 1.4 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EAU88687.1 - 8.4e-08 32.4 4.3 8.4e-08 32.4 3.0 3.1 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EAU88687.1 - 1.3e-05 24.8 3.2 1.3e-05 24.8 2.2 3.6 2 2 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EAU88687.1 - 0.00011 22.1 3.8 0.00011 22.1 2.7 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF1353 PF07087.6 EAU88688.2 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1353) RTC4 PF14474.1 EAU88689.2 - 3.5e-11 43.1 0.0 9.2e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain Maf_N PF08383.6 EAU88689.2 - 0.27 10.8 0.9 0.47 10.0 0.1 1.8 2 0 0 2 2 2 0 Maf N-terminal region Mit_ribos_Mrp51 PF11709.3 EAU88692.1 - 3.6e-14 52.6 0.2 1.8e-13 50.3 0.2 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit UPF1_Zn_bind PF09416.5 EAU88694.1 - 2.7e-70 234.8 3.0 2.7e-70 234.8 2.1 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EAU88694.1 - 7.5e-59 198.4 0.0 1.4e-58 197.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU88694.1 - 1.1e-55 188.8 2.0 1.6e-55 188.2 1.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU88694.1 - 1.4e-14 53.5 0.7 3.8e-14 52.1 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAU88694.1 - 2.9e-13 49.8 0.3 3.5e-12 46.3 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EAU88694.1 - 2.5e-08 33.9 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EAU88694.1 - 3.8e-06 26.6 0.0 0.1 12.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EAU88694.1 - 5.2e-06 25.6 0.0 6.1e-05 22.1 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EAU88694.1 - 3e-05 23.4 0.1 0.0021 17.4 0.1 2.4 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EAU88694.1 - 0.0001 21.9 0.1 0.00022 20.8 0.1 1.6 1 0 0 1 1 1 1 Helicase DEAD PF00270.24 EAU88694.1 - 0.0044 16.5 0.3 0.01 15.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.2 EAU88694.1 - 0.0095 15.3 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 EAU88694.1 - 0.015 14.7 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_S13_N PF08069.7 EAU88694.1 - 0.015 15.1 0.2 0.062 13.1 0.0 2.1 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain PIF1 PF05970.9 EAU88694.1 - 0.021 13.7 0.2 1.3 7.9 0.0 2.2 1 1 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.1 EAU88694.1 - 0.031 14.4 0.1 0.091 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EAU88694.1 - 0.033 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ribosomal_S27e PF01667.12 EAU88694.1 - 0.055 13.0 0.6 0.17 11.4 0.4 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 PhoH PF02562.11 EAU88694.1 - 0.068 12.3 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EAU88694.1 - 0.074 12.1 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 EAU88694.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EAU88694.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Nop14 PF04147.7 EAU88695.1 - 0.027 12.4 8.7 0.037 11.9 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family Metallophos PF00149.23 EAU88697.1 - 2e-10 40.4 6.5 3e-09 36.5 4.5 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU88697.1 - 5.2e-07 29.6 0.0 8.4e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lactamase_B_2 PF12706.2 EAU88697.1 - 0.57 9.6 4.2 3.5 7.1 3.0 2.1 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF2204 PF09970.4 EAU88698.1 - 0.00019 20.9 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) Radical_SAM PF04055.16 EAU88700.1 - 1.8e-16 60.7 0.2 6e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EAU88700.1 - 1.3e-12 47.5 0.0 4e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAU88700.1 - 0.021 14.9 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAU88700.1 - 0.034 13.9 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF2404 PF10296.4 EAU88701.2 - 1.1e-05 25.4 0.0 0.00031 20.8 0.0 2.5 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Adap_comp_sub PF00928.16 EAU88701.2 - 0.1 11.7 0.1 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Adaptor complexes medium subunit family F-box-like PF12937.2 EAU88702.2 - 0.00012 21.6 0.4 0.00035 20.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like APG9 PF04109.11 EAU88703.2 - 5.6e-134 446.6 0.0 1.3e-101 340.2 0.0 2.1 1 1 1 2 2 2 2 Autophagy protein Apg9 HMGL-like PF00682.14 EAU88704.1 - 3.5e-60 203.6 0.0 5.8e-60 202.8 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EAU88704.1 - 8.9e-45 151.7 0.0 7.8e-22 77.5 0.0 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain tRNA-synt_1c PF00749.16 EAU88705.1 - 3.3e-109 364.3 0.0 4.4e-109 363.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EAU88705.1 - 6.3e-36 123.6 0.0 1.2e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.1 EAU88705.1 - 9.2e-07 28.6 0.1 2.2e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU88705.1 - 2.1e-06 28.1 0.8 7.7e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU88705.1 - 1e-05 25.3 0.0 2.9e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EAU88705.1 - 0.014 14.5 2.1 0.024 13.7 0.7 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain NUDIX PF00293.23 EAU88706.1 - 3.8e-10 39.5 0.0 6.1e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain CPDase PF07823.6 EAU88707.1 - 5.3e-19 68.4 0.0 5.9e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EAU88707.1 - 4.6e-07 29.6 0.1 0.00032 20.4 0.0 2.2 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 EAU88707.1 - 0.0028 17.5 0.0 0.0064 16.4 0.0 1.6 2 0 0 2 2 2 1 LigT like Phosphoesterase DUF1776 PF08643.5 EAU88708.1 - 4.8e-17 62.0 0.0 7.3e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ATP-synt_ab PF00006.20 EAU88709.2 - 7.2e-64 215.2 0.2 1.9e-63 213.8 0.0 1.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAU88709.2 - 1.1e-25 90.3 1.4 2e-25 89.4 1.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain NB-ARC PF00931.17 EAU88709.2 - 0.0061 15.4 0.8 0.023 13.5 0.1 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 EAU88709.2 - 0.012 15.0 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAU88709.2 - 0.012 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EAU88709.2 - 0.013 15.7 0.0 0.3 11.2 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EAU88709.2 - 0.017 14.7 0.2 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EAU88709.2 - 0.018 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EAU88709.2 - 0.024 14.6 0.1 0.096 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain KaiC PF06745.8 EAU88709.2 - 0.025 13.6 0.7 0.054 12.6 0.1 1.8 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.1 EAU88709.2 - 0.032 14.3 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EAU88709.2 - 0.041 13.0 0.1 0.076 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EAU88709.2 - 0.11 12.7 0.2 0.4 10.9 0.1 1.9 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 EAU88709.2 - 0.12 12.5 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase F-box-like PF12937.2 EAU88710.1 - 0.0014 18.2 2.2 0.0039 16.8 1.5 1.9 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EAU88710.1 - 0.17 12.1 5.6 64 4.4 0.0 5.3 5 0 0 5 5 5 0 Leucine rich repeat WD40 PF00400.27 EAU88711.2 - 4.9e-84 273.4 10.1 1.3e-12 47.0 0.0 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAU88711.2 - 7.3e-08 30.9 8.0 0.038 12.1 0.1 5.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAU88711.2 - 4e-06 25.8 0.1 0.36 9.5 0.0 3.2 2 1 0 3 3 3 3 Nup133 N terminal like eIF2A PF08662.6 EAU88711.2 - 0.0019 17.9 0.0 0.11 12.1 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A bZIP_2 PF07716.10 EAU88711.2 - 0.033 14.0 0.5 0.06 13.1 0.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Pro_CA PF00484.14 EAU88712.2 - 2.8e-28 98.8 0.8 3.8e-25 88.6 0.3 2.9 2 1 0 2 2 2 2 Carbonic anhydrase NADH_dehy_S2_C PF06444.6 EAU88712.2 - 0.38 11.0 4.8 0.89 9.9 3.3 1.6 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Zn_clus PF00172.13 EAU88713.2 - 9.4e-09 35.0 9.5 1.4e-08 34.4 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EAU88714.2 - 8e-42 142.8 0.9 3.7e-41 140.7 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EAU88714.2 - 1.6e-31 109.1 0.1 4.3e-31 107.8 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EAU88714.2 - 1.3e-15 56.5 0.1 2.7e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EAU88714.2 - 1.3e-14 54.6 0.0 2.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EAU88714.2 - 0.02 15.2 0.0 0.043 14.0 0.0 1.7 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Ins_P5_2-kin PF06090.7 EAU88715.1 - 8.6e-55 185.9 0.0 1.1e-54 185.6 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Pkinase PF00069.20 EAU88716.1 - 1.1e-44 152.5 0.0 1.7e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88716.1 - 3.4e-19 68.9 0.0 1.5e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU88716.1 - 3.2e-05 23.0 0.0 6.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU88716.1 - 0.0028 17.4 1.6 0.024 14.3 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family BTB PF00651.26 EAU88717.2 - 0.015 15.2 0.0 0.095 12.6 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.11 EAU88718.2 - 7.6e-32 110.3 32.3 7.6e-32 110.3 22.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU88718.2 - 2.2e-08 33.1 14.0 2.2e-08 33.1 7.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter SKN1 PF03935.10 EAU88719.1 - 6e-194 644.8 0.2 7e-194 644.6 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DASH_Dad3 PF08656.5 EAU88720.1 - 2.9e-22 78.1 0.1 3.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF3261 PF11659.3 EAU88720.1 - 0.04 13.5 0.2 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3261) WD40 PF00400.27 EAU88721.2 - 1.9e-20 71.9 12.5 3.3e-08 33.1 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Rax2 PF12768.2 EAU88721.2 - 3.1e-06 26.6 0.3 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 EAU88721.2 - 0.0016 17.1 1.6 0.051 12.1 0.3 2.7 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EAU88721.2 - 0.0027 17.4 0.6 0.47 10.1 0.0 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PAS PF00989.19 EAU88722.2 - 0.041 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold DUF4510 PF14971.1 EAU88722.2 - 0.1 12.7 0.1 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) adh_short_C2 PF13561.1 EAU88723.2 - 2.6e-31 109.2 0.1 3.3e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU88723.2 - 1.3e-23 83.7 1.0 1.7e-23 83.3 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU88723.2 - 9.5e-10 38.4 0.5 1.4e-09 37.9 0.4 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EAU88723.2 - 0.0032 16.4 0.0 0.0045 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EAU88723.2 - 0.0037 16.7 0.1 0.012 15.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Kinesin PF00225.18 EAU88724.2 - 1.4e-98 329.7 0.0 2.2e-57 194.2 0.0 4.2 5 0 0 5 5 5 2 Kinesin motor domain Fib_alpha PF08702.5 EAU88724.2 - 0.00015 21.9 5.3 0.00015 21.9 3.7 12.7 7 3 5 13 13 13 3 Fibrinogen alpha/beta chain family IncA PF04156.9 EAU88724.2 - 0.00021 20.9 12.0 0.00021 20.9 8.3 14.3 5 2 7 13 13 13 4 IncA protein Macoilin PF09726.4 EAU88724.2 - 0.00088 17.6 13.0 0.00088 17.6 9.0 6.3 2 1 4 6 6 6 2 Transmembrane protein SlyX PF04102.7 EAU88724.2 - 0.0069 16.7 2.9 0.0069 16.7 2.0 16.8 12 6 6 19 19 19 5 SlyX DUF1189 PF06691.6 EAU88724.2 - 0.018 14.3 1.7 0.06 12.6 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Arginase PF00491.16 EAU88725.1 - 8.4e-77 258.1 0.0 9.9e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.16 EAU88726.2 - 2.9e-31 108.7 0.0 3.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CwfJ_C_1 PF04677.10 EAU88727.2 - 1.9e-30 105.0 0.0 3.4e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EAU88727.2 - 1.2e-19 70.5 0.0 2.2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 EAU88727.2 - 5.6e-13 48.1 18.7 2.5e-06 26.8 1.7 3.6 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 EAU88727.2 - 3e-07 30.0 17.6 0.0015 18.3 0.2 4.1 4 0 0 4 4 4 3 Zinc knuckle eIF3g PF12353.3 EAU88727.2 - 0.00079 19.3 11.0 0.68 9.8 0.6 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 EAU88727.2 - 0.22 11.2 7.0 12 5.7 0.1 3.4 1 1 2 3 3 3 0 Zinc knuckle C1_3 PF07649.7 EAU88727.2 - 4.5 7.3 6.4 18 5.4 0.1 3.3 3 0 0 3 3 3 0 C1-like domain COesterase PF00135.23 EAU88729.2 - 4.1e-64 217.1 0.0 6.7e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU88729.2 - 1.6e-14 54.0 0.0 2.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU88729.2 - 0.16 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family NIF PF03031.13 EAU88730.2 - 4.6e-22 78.3 0.0 8.5e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EAU88730.2 - 0.038 13.3 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family TBD PF12845.2 EAU88731.1 - 0.029 13.9 0.8 0.29 10.6 0.2 2.3 1 1 1 2 2 2 0 TBD domain Tyrosinase PF00264.15 EAU88731.1 - 0.097 12.8 0.2 0.96 9.5 0.0 2.0 2 0 0 2 2 2 0 Common central domain of tyrosinase Phage_rep_O PF04492.8 EAU88731.1 - 0.12 12.6 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage replication protein O PCI_Csn8 PF10075.4 EAU88732.2 - 4e-18 65.5 0.0 1.7e-17 63.5 0.0 1.8 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EAU88732.2 - 5e-05 22.9 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EAU88732.2 - 0.044 14.0 0.1 0.08 13.2 0.1 1.5 1 0 0 1 1 1 0 PCI domain DUF1681 PF07933.9 EAU88733.1 - 4.3e-49 166.1 0.0 6.6e-49 165.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Glyco_hydro_6 PF01341.12 EAU88734.1 - 1.6e-107 359.3 0.6 2e-107 359.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EAU88734.1 - 3.5e-13 48.9 7.2 7.2e-13 47.9 5.0 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Gag_p24 PF00607.15 EAU88734.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Aminotran_5 PF00266.14 EAU88735.2 - 2.1e-96 322.9 0.0 2.5e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EAU88735.2 - 0.00015 20.9 0.1 0.00075 18.6 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family RRM_1 PF00076.17 EAU88736.2 - 1.5e-27 94.9 0.0 4.9e-17 61.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU88736.2 - 1.7e-21 75.9 0.0 4e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU88736.2 - 7.2e-16 57.7 0.0 1.2e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU88736.2 - 0.0012 18.6 0.0 0.065 13.0 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EAU88736.2 - 0.0019 17.9 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EAU88736.2 - 0.0045 16.7 0.1 2.1 8.1 0.1 2.4 2 0 0 2 2 2 2 Limkain b1 CAP_GLY PF01302.20 EAU88737.2 - 8.5e-15 54.2 0.1 1.7e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EAU88737.2 - 1.2e-11 43.9 5.5 0.00026 20.5 0.4 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EAU88737.2 - 2e-09 37.2 0.0 5.1e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 EAU88737.2 - 0.00016 21.3 1.7 2.4 8.5 0.3 5.1 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.1 EAU88737.2 - 0.00022 20.9 7.0 0.024 14.4 1.0 3.8 2 1 4 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EAU88737.2 - 0.00034 20.2 3.9 2.9 8.2 0.2 5.6 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EAU88737.2 - 0.02 14.9 3.7 1e+02 3.8 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat ECH_C PF13766.1 EAU88738.2 - 1.7e-29 102.3 0.2 1.7e-29 102.3 0.1 1.8 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EAU88738.2 - 5.4e-22 78.1 0.0 4.2e-21 75.1 0.0 2.4 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family IDO PF01231.13 EAU88739.2 - 1.6e-110 369.4 0.0 2e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.5 EAU88740.1 - 7.1e-48 162.0 3.0 1e-45 155.0 1.3 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EAU88740.1 - 5.4e-19 67.8 0.1 1.2e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EAU88740.1 - 1.4e-15 56.8 0.1 2.5e-11 43.2 0.0 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain Peptidase_M16 PF00675.15 EAU88742.1 - 6e-40 136.4 3.2 5.4e-38 130.0 0.0 3.0 2 1 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAU88742.1 - 3.6e-21 75.6 0.1 5.9e-11 42.3 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain CKS PF01111.14 EAU88743.2 - 1.2e-35 121.1 0.3 1.4e-35 120.8 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Sec63 PF02889.11 EAU88744.2 - 7e-47 160.1 0.0 1.2e-46 159.4 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EAU88744.2 - 1.2e-20 73.6 0.0 3.5e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU88744.2 - 4.5e-09 36.4 0.0 3.8e-07 30.1 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EAU88744.2 - 1.1e-07 31.6 0.1 3e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EAU88744.2 - 7.5e-05 22.8 0.0 0.00042 20.4 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain T2SE PF00437.15 EAU88744.2 - 0.015 14.2 0.0 0.053 12.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EAU88744.2 - 0.026 14.2 0.0 0.095 12.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EAU88744.2 - 0.044 13.9 0.2 0.44 10.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF4407 PF14362.1 EAU88746.1 - 0.00034 19.6 6.9 0.00037 19.5 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 EAU88746.1 - 0.011 13.6 0.9 0.013 13.3 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NYD-SP28_assoc PF14775.1 EAU88746.1 - 0.029 14.0 0.4 0.029 14.0 0.3 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain DUF3584 PF12128.3 EAU88746.1 - 0.045 11.0 16.8 0.056 10.7 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) M PF02370.11 EAU88746.1 - 0.064 13.6 7.4 1.3 9.5 1.2 3.5 2 1 1 3 3 3 0 M protein repeat CorA PF01544.13 EAU88746.1 - 0.072 12.1 2.7 0.1 11.6 1.9 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HALZ PF02183.13 EAU88746.1 - 0.084 12.6 0.3 0.084 12.6 0.2 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper ADIP PF11559.3 EAU88746.1 - 0.086 12.7 23.3 0.61 9.9 10.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 EAU88746.1 - 0.13 12.0 13.1 0.063 13.1 7.6 1.6 2 0 0 2 2 1 0 Axonemal dynein light chain bZIP_2 PF07716.10 EAU88746.1 - 0.22 11.3 0.2 0.22 11.3 0.1 3.3 2 1 1 3 3 3 0 Basic region leucine zipper DUF4200 PF13863.1 EAU88746.1 - 0.24 11.3 15.5 2.5 8.0 0.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 EAU88746.1 - 0.26 10.2 15.0 0.37 9.6 10.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EAU88746.1 - 0.3 10.6 14.0 0.45 10.0 9.7 1.2 1 0 0 1 1 1 0 IncA protein Sulphotransf PF09037.5 EAU88746.1 - 0.42 10.0 8.8 0.4 10.1 5.0 1.8 2 1 0 2 2 2 0 Stf0 sulphotransferase Tropomyosin_1 PF12718.2 EAU88746.1 - 0.72 9.6 16.1 4.2 7.2 9.8 2.0 1 1 1 2 2 2 0 Tropomyosin like OmpH PF03938.9 EAU88746.1 - 1.5 8.7 15.5 2.8 7.8 10.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EAU88746.1 - 1.7 6.9 6.6 2.2 6.6 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 EAU88746.1 - 1.8 6.8 9.9 2.6 6.3 6.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HAUS6_N PF14661.1 EAU88746.1 - 1.9 7.7 14.6 2.7 7.2 10.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 EAU88746.1 - 3.1 6.7 15.1 5.4 5.9 10.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 EAU88746.1 - 3.6 7.1 16.9 3.3 7.2 3.8 2.8 1 1 1 2 2 2 0 Septum formation initiator DUF2968 PF11180.3 EAU88746.1 - 4.4 6.6 26.5 0.6 9.4 15.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Mnd1 PF03962.10 EAU88746.1 - 4.9 6.7 13.9 5.4 6.6 8.9 1.5 1 1 0 1 1 1 0 Mnd1 family Spc24 PF08286.6 EAU88746.1 - 6.7 6.4 12.3 5.3 6.7 0.5 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Exo_endo_phos PF03372.18 EAU88747.2 - 2.6e-18 66.8 0.1 3.8e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pro_CA PF00484.14 EAU88748.1 - 1.5e-42 145.2 0.0 1.9e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Abhydrolase_6 PF12697.2 EAU88748.1 - 0.081 12.7 1.1 0.45 10.3 0.3 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L30_N PF08079.7 EAU88749.1 - 1.4e-26 92.2 18.7 3e-26 91.2 13.0 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EAU88749.1 - 2.4e-19 68.6 1.0 5.2e-19 67.5 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF912 PF06024.7 EAU88750.2 - 0.0061 16.5 0.0 0.038 14.0 0.0 2.1 2 1 1 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 EAU88750.2 - 0.011 16.0 0.0 0.61 10.5 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PDGLE PF13190.1 EAU88750.2 - 0.055 13.1 0.4 0.51 10.0 0.2 2.3 2 1 0 2 2 2 0 PDGLE domain Herpes_gE PF02480.11 EAU88750.2 - 0.45 8.7 0.0 0.45 8.7 0.0 3.1 2 1 0 3 3 3 0 Alphaherpesvirus glycoprotein E PepSY_TM PF03929.11 EAU88750.2 - 0.83 10.1 3.6 1.6 9.2 2.5 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix Aldo_ket_red PF00248.16 EAU88751.1 - 6.9e-44 149.7 0.0 9.5e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Herpes_gE PF02480.11 EAU88752.2 - 0.0076 14.5 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EAU88752.2 - 0.011 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 EAU88753.2 - 0.022 13.0 0.0 0.034 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PDGLE PF13190.1 EAU88753.2 - 0.026 14.1 0.7 0.075 12.7 0.5 1.7 1 1 0 1 1 1 0 PDGLE domain Phage_Coat_B PF05356.6 EAU88753.2 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Phage Coat protein B DUF1191 PF06697.7 EAU88753.2 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Cytochrom_B_N PF00033.14 EAU88753.2 - 0.17 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Syndecan PF01034.15 EAU88754.2 - 0.018 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EAU88754.2 - 0.14 11.5 0.3 0.26 10.6 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Snf7 PF03357.16 EAU88757.2 - 3.4e-14 52.5 7.6 5.2e-14 51.9 5.3 1.3 1 0 0 1 1 1 1 Snf7 Laminin_II PF06009.7 EAU88757.2 - 0.029 14.1 8.8 0.12 12.1 1.8 2.4 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.7 EAU88757.2 - 0.21 11.8 2.6 2.1 8.6 0.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EAU88757.2 - 0.39 10.5 4.7 0.39 10.5 1.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EAU88757.2 - 2 8.2 6.0 0.35 10.7 0.9 2.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HSP9_HSP12 PF04119.7 EAU88758.1 - 2.4e-20 72.3 11.1 2.4e-20 72.3 7.7 1.9 2 0 0 2 2 2 1 Heat shock protein 9/12 SLX9 PF15341.1 EAU88758.1 - 0.053 13.9 2.7 0.065 13.6 1.9 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF3484 PF11983.3 EAU88758.1 - 0.053 14.3 1.8 0.57 11.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) CAML PF14963.1 EAU88758.1 - 0.61 9.4 4.0 0.61 9.4 2.8 1.0 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand OTU PF02338.14 EAU88759.1 - 1e-10 42.2 0.0 1.7e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease DUF555 PF04475.7 EAU88759.1 - 0.051 13.5 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF555) zf-C2H2_2 PF12756.2 EAU88759.1 - 0.094 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Exo_endo_phos PF03372.18 EAU88760.2 - 3.7e-18 66.3 0.0 4.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EAU88760.2 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase MAGE_N PF12440.3 EAU88761.2 - 0.067 13.4 7.6 0.7 10.2 0.5 2.6 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal Myb_DNA-bind_2 PF08914.6 EAU88762.1 - 0.061 13.1 0.3 0.3 10.9 0.2 2.0 1 1 0 1 1 1 0 Rap1 Myb domain Gtr1_RagA PF04670.7 EAU88763.2 - 3.6e-79 265.1 0.2 7.2e-79 264.1 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EAU88763.2 - 4.3e-05 22.9 0.1 0.00016 21.1 0.0 1.8 2 0 0 2 2 2 1 Ras family Arf PF00025.16 EAU88763.2 - 7.9e-05 21.9 0.1 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EAU88763.2 - 0.0046 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Telomere_reg-2 PF10193.4 EAU88763.2 - 0.066 13.4 0.1 0.86 9.8 0.0 2.4 2 0 0 2 2 2 0 Telomere length regulation protein DMRL_synthase PF00885.14 EAU88764.1 - 1.1e-47 161.3 0.0 1.5e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.7 EAU88765.1 - 3.9e-24 84.9 3.0 1.4e-23 83.1 2.1 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain Abhydrolase_6 PF12697.2 EAU88766.2 - 2.6e-20 73.2 0.0 3.3e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU88766.2 - 2.5e-12 46.8 0.0 7.5e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU88766.2 - 1.1e-08 34.8 0.0 2.4e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EAU88766.2 - 0.012 15.3 0.0 5.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.11 EAU88766.2 - 0.014 14.8 0.1 4.1 6.7 0.0 2.6 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EAU88766.2 - 0.045 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2048 PF09752.4 EAU88766.2 - 0.049 12.5 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PGAP1 PF07819.8 EAU88766.2 - 0.064 12.8 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.3 EAU88766.2 - 0.11 12.3 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 EAU88766.2 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Lipase_2 PF01674.13 EAU88766.2 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Peptidase_S10 PF00450.17 EAU88766.2 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase ATP_bind_3 PF01171.15 EAU88767.2 - 2e-29 102.3 0.0 3e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF445 PF04286.7 EAU88767.2 - 0.11 12.0 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) YTH PF04146.10 EAU88768.2 - 1.8e-47 160.4 0.1 3.1e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain CALCOCO1 PF07888.6 EAU88768.2 - 0.11 10.7 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF533 PF04391.7 EAU88768.2 - 5.4 6.3 7.7 25 4.1 5.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Pyr_redox_2 PF07992.9 EAU88769.1 - 4.1e-23 82.3 0.0 6e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EAU88769.1 - 4.7e-11 41.1 2.7 8.9e-05 21.5 0.5 2.4 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.22 EAU88769.1 - 6e-09 36.1 0.1 1.7e-06 28.3 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 EAU88769.1 - 4.8e-08 33.0 0.8 1e-07 31.9 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EAU88769.1 - 8.3e-08 31.5 0.4 0.0069 16.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EAU88769.1 - 0.00021 20.4 1.2 0.0098 15.2 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EAU88769.1 - 0.0019 17.7 1.9 0.84 9.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EAU88769.1 - 0.041 13.9 0.6 0.82 9.7 0.2 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NAD_binding_7 PF13241.1 EAU88769.1 - 0.056 13.7 0.1 0.44 10.8 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding EF-hand_4 PF12763.2 EAU88769.1 - 0.38 10.4 2.4 35 4.1 0.2 3.1 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand A_deaminase PF00962.17 EAU88771.2 - 8.3e-50 169.5 0.0 1e-49 169.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EAU88771.2 - 0.00012 22.0 0.0 0.00037 20.4 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal KH_1 PF00013.24 EAU88772.2 - 2.1e-37 126.5 7.8 1e-13 50.7 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EAU88772.2 - 1e-28 98.4 12.8 1.3e-09 37.4 0.8 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EAU88772.2 - 4e-14 51.9 5.4 0.00074 19.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EAU88772.2 - 4.1e-05 23.1 0.7 0.31 10.6 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EAU88772.2 - 0.49 10.2 5.7 19 5.1 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain Brix PF04427.13 EAU88773.1 - 1.5e-36 125.8 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF1732 PF08340.6 EAU88775.2 - 0.051 13.3 0.3 0.051 13.3 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1732) DUF972 PF06156.8 EAU88775.2 - 0.27 11.6 12.2 2.2 8.6 0.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Hid1 PF12722.2 EAU88775.2 - 0.76 7.3 14.8 1.1 6.8 10.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATG16 PF08614.6 EAU88775.2 - 1.9 8.2 32.7 0.16 11.7 2.9 3.3 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 EAU88775.2 - 2 6.7 26.2 0.42 9.0 16.0 1.4 1 1 0 1 1 1 0 AAA domain Tho2 PF11262.3 EAU88775.2 - 5 6.0 12.8 0.65 8.9 1.3 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF1664 PF07889.7 EAU88775.2 - 5.3 6.8 10.8 0.91 9.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF848 PF05852.6 EAU88775.2 - 5.3 6.8 19.4 0.11 12.2 2.9 2.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Asparaginase PF00710.15 EAU88776.2 - 2.4e-120 401.1 0.0 3.2e-120 400.7 0.0 1.2 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EAU88776.2 - 1.3e-14 54.3 0.2 3.2e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAU88776.2 - 7.2e-14 50.7 4.3 5.3e-07 29.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EAU88776.2 - 2.3e-13 50.2 0.1 2.2e-07 31.2 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU88776.2 - 3.8e-12 45.1 0.5 0.00037 20.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EAU88776.2 - 2.6e-10 40.1 0.9 5.1e-08 32.8 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) IF-2B PF01008.12 EAU88779.2 - 3.1e-64 216.6 0.0 3.6e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family LepA_C PF06421.7 EAU88780.2 - 1.6e-41 140.5 0.1 3.3e-41 139.5 0.1 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 EAU88780.2 - 4.9e-40 136.9 0.0 7.4e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EAU88780.2 - 1.6e-17 63.0 0.0 3.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EAU88780.2 - 1.4e-07 31.5 0.0 3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EAU88780.2 - 1.2e-05 25.0 0.0 3.6e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EAU88780.2 - 0.00062 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Ras family cwf18 PF08315.7 EAU88781.1 - 1.2e-31 109.8 6.1 1.9e-31 109.2 4.2 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Jnk-SapK_ap_N PF09744.4 EAU88781.1 - 0.044 13.7 2.2 0.069 13.1 1.5 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4238 PF14022.1 EAU88781.1 - 0.08 12.1 1.1 0.11 11.7 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) GvpL_GvpF PF06386.6 EAU88781.1 - 0.086 12.4 2.7 0.11 12.0 1.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Gti1_Pac2 PF09729.4 EAU88782.1 - 1.2e-26 93.5 0.2 1.1e-24 87.1 0.1 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family Elongin_A PF06881.6 EAU88783.2 - 6.2e-18 65.1 0.4 9.9e-18 64.5 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A WD40 PF00400.27 EAU88784.2 - 7.5e-38 127.0 15.4 3.7e-09 36.1 0.2 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EAU88784.2 - 0.019 14.4 0.1 0.56 9.6 0.0 2.6 2 2 0 2 2 2 0 PQQ-like domain DUF4221 PF13970.1 EAU88784.2 - 0.024 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Coatomer_WDAD PF04053.9 EAU88784.2 - 0.039 12.7 0.8 3.1 6.5 0.0 2.4 2 1 0 2 2 2 0 Coatomer WD associated region Ecl1 PF12855.2 EAU88785.2 - 6e-05 22.2 2.3 6e-05 22.2 1.6 2.1 2 0 0 2 2 2 1 Life-span regulatory factor ADP_ribosyl_GH PF03747.9 EAU88786.2 - 9.9e-50 169.9 0.1 2.4e-49 168.6 0.1 1.6 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase Vps54 PF07928.7 EAU88787.2 - 1.8e-50 170.5 3.0 4.4e-50 169.3 2.0 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EAU88787.2 - 1.1e-06 27.8 0.1 3.7e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec6 PF06046.8 EAU88787.2 - 0.017 13.2 0.1 0.029 12.4 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec6 Sec8_exocyst PF04048.9 EAU88787.2 - 0.045 13.3 0.1 0.15 11.6 0.1 1.9 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain PPR PF01535.15 EAU88787.2 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 PPR repeat GST_C_3 PF14497.1 EAU88788.1 - 0.0018 18.7 0.0 0.007 16.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU88788.1 - 0.01 15.6 0.1 0.041 13.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EAU88788.1 - 0.039 13.8 0.3 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF2731 PF10806.3 EAU88788.1 - 0.058 13.6 0.1 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2731) TRAM_LAG1_CLN8 PF03798.11 EAU88789.1 - 1.8e-29 102.7 16.5 1.8e-29 102.7 11.4 1.8 2 0 0 2 2 2 1 TLC domain NAD_binding_7 PF13241.1 EAU88790.1 - 1.7e-28 98.8 0.0 3.2e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EAU88790.1 - 2.8e-18 64.9 0.2 6.5e-18 63.8 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EAU88790.1 - 7.1e-17 60.0 0.3 1.2e-16 59.3 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central 2-Hacid_dh_C PF02826.14 EAU88790.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAU88790.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 1 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EAU88790.1 - 0.13 12.0 0.1 0.85 9.4 0.0 2.0 2 0 0 2 2 2 0 ThiF family zf-CCCH_2 PF14608.1 EAU88791.1 - 0.0045 16.9 1.8 0.013 15.4 1.3 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type RRM_6 PF14259.1 EAU88791.1 - 0.039 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU88791.1 - 0.075 12.6 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cript PF10235.4 EAU88791.1 - 0.37 11.1 4.4 2.8 8.3 0.6 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-CCCH PF00642.19 EAU88791.1 - 0.67 9.6 7.9 0.045 13.4 1.6 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zn_ribbon_recom PF13408.1 EAU88791.1 - 1.7 8.9 6.6 0.24 11.7 1.4 1.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain LEA_2 PF03168.8 EAU88793.2 - 0.00022 21.5 0.1 0.00047 20.4 0.0 1.6 2 0 0 2 2 2 1 Late embryogenesis abundant protein Vac7 PF12751.2 EAU88793.2 - 0.0018 17.1 0.5 0.0028 16.5 0.3 1.4 1 1 0 1 1 1 1 Vacuolar segregation subunit 7 Pkinase PF00069.20 EAU88797.2 - 2.2e-35 122.0 0.0 2.6e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88797.2 - 1.1e-12 47.6 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Vac_ImportDeg PF09783.4 EAU88798.2 - 6.7e-58 195.0 0.1 9e-52 175.1 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein MFS_1 PF07690.11 EAU88799.2 - 3.5e-37 127.9 30.3 2.1e-35 122.0 22.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EAU88799.2 - 7.2e-10 37.6 9.9 1.5e-09 36.6 6.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EAU88799.2 - 4e-09 35.5 25.9 1.6e-07 30.2 7.0 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 EAU88799.2 - 0.00016 20.3 13.4 0.0085 14.6 3.5 2.8 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like TLC PF03219.9 EAU88799.2 - 0.016 13.7 0.2 0.016 13.7 0.2 2.1 3 0 0 3 3 3 0 TLC ATP/ADP transporter MerE PF05052.7 EAU88799.2 - 0.053 13.5 2.1 1 9.4 0.5 2.6 2 0 0 2 2 2 0 MerE protein DUF2754 PF10953.3 EAU88799.2 - 0.06 13.4 2.7 0.069 13.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) IncA PF04156.9 EAU88799.2 - 0.56 9.7 5.6 0.059 12.9 0.4 2.0 2 0 0 2 2 2 0 IncA protein DUF202 PF02656.10 EAU88799.2 - 3.1 8.0 13.0 3.1 8.0 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Ras PF00071.17 EAU88800.1 - 2.7e-50 169.9 0.0 3.1e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU88800.1 - 4.1e-16 59.5 0.0 6.7e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU88800.1 - 4.6e-10 39.0 0.0 6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU88800.1 - 0.00012 21.3 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EAU88800.1 - 0.0071 15.0 2.2 1 7.9 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 EAU88800.1 - 0.022 14.9 0.1 0.17 12.0 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 EAU88800.1 - 0.031 13.5 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EAU88800.1 - 0.044 13.9 0.1 0.13 12.3 0.0 1.7 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU88800.1 - 0.095 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 EAU88800.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 STAS domain UPF0079 PF02367.12 EAU88800.1 - 0.15 11.6 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KOW PF00467.24 EAU88802.1 - 1.8e-10 40.1 5.3 5.4e-10 38.5 3.4 1.9 2 0 0 2 2 2 1 KOW motif ATP-synt_D PF01813.12 EAU88803.1 - 3.5e-62 209.4 2.2 5.7e-62 208.7 1.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit D DUF1151 PF06625.6 EAU88803.1 - 0.053 13.2 0.5 0.053 13.2 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) XAP5 PF04921.9 EAU88804.2 - 2.9e-96 321.6 1.4 2.9e-96 321.6 1.0 2.1 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF3453 PF11935.3 EAU88804.2 - 0.66 9.3 4.6 1 8.6 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Ribosomal_S13 PF00416.17 EAU88805.2 - 5.7e-21 74.9 0.0 1.1e-20 74.0 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S13/S18 IMS_HHH PF11798.3 EAU88805.2 - 0.016 15.1 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif FbpA PF05833.6 EAU88805.2 - 0.034 12.6 0.1 0.15 10.5 0.0 1.8 1 1 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) TRAPP PF04051.11 EAU88806.2 - 1.5e-36 125.1 0.0 1.9e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WBS_methylT PF12589.3 EAU88807.1 - 3.8e-21 75.3 11.0 3.8e-21 75.3 7.6 1.5 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EAU88807.1 - 7.7e-09 35.9 0.0 2.1e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU88807.1 - 1.5e-06 28.0 0.0 3e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU88807.1 - 0.00011 22.5 0.3 0.00046 20.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU88807.1 - 0.00015 21.3 0.0 0.00037 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU88807.1 - 0.0012 19.3 0.1 0.0023 18.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EAU88807.1 - 0.012 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_25 PF13649.1 EAU88807.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain BCS1_N PF08740.6 EAU88808.2 - 2.6e-51 173.9 4.9 3.4e-51 173.5 3.4 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EAU88808.2 - 5.1e-18 65.5 0.0 1e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EAU88808.2 - 7e-06 25.5 0.1 4.6e-05 22.9 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EAU88808.2 - 6.1e-05 23.8 0.0 0.00013 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU88808.2 - 0.0016 18.4 0.1 0.0075 16.2 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.1 EAU88808.2 - 0.0031 17.3 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU88808.2 - 0.0039 17.3 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_21 PF13304.1 EAU88808.2 - 0.0052 16.7 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU88808.2 - 0.009 16.3 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EAU88808.2 - 0.011 14.6 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 EAU88808.2 - 0.016 14.8 0.0 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EAU88808.2 - 0.018 14.6 0.2 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EAU88808.2 - 0.021 15.1 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAU88808.2 - 0.029 13.9 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EAU88808.2 - 0.037 13.7 0.0 0.12 12.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EAU88808.2 - 0.037 13.1 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EAU88808.2 - 0.038 14.1 0.0 0.082 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EAU88808.2 - 0.068 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.1 EAU88808.2 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAU88808.2 - 0.081 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EAU88808.2 - 0.099 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Lipase_GDSL_3 PF14606.1 EAU88808.2 - 0.15 11.7 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DnaJ PF00226.26 EAU88809.1 - 3.2e-15 55.6 0.0 1.3e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 DnaJ domain Ank_2 PF12796.2 EAU88809.1 - 8.5e-14 51.6 0.0 3e-12 46.7 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAU88809.1 - 7.5e-11 41.1 0.0 0.008 16.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EAU88809.1 - 1.5e-10 40.2 0.0 0.00011 21.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EAU88809.1 - 2e-10 40.9 0.0 8.5e-10 38.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU88809.1 - 1.3e-08 34.8 0.0 5.4e-08 32.8 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) API5 PF05918.6 EAU88809.1 - 0.008 14.7 1.5 0.008 14.7 1.0 1.9 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) RR_TM4-6 PF06459.7 EAU88809.1 - 1.2 8.9 14.5 0.088 12.6 4.1 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ubiquitin PF00240.18 EAU88811.1 - 3.3e-12 45.6 0.4 6e-12 44.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EAU88811.1 - 2.8e-07 30.1 0.3 5.2e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUSP PF06337.7 EAU88811.1 - 5e-05 23.6 0.0 0.0001 22.6 0.0 1.6 1 0 0 1 1 1 1 DUSP domain zf-RanBP PF00641.13 EAU88811.1 - 0.0081 15.2 2.1 0.018 14.1 1.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UN_NPL4 PF11543.3 EAU88811.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 LUC7 PF03194.10 EAU88813.2 - 1.7e-71 240.7 5.5 2e-71 240.4 3.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Atg14 PF10186.4 EAU88813.2 - 0.0016 17.4 1.5 0.0024 16.8 1.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Ada3 PF10198.4 EAU88813.2 - 0.0074 16.0 1.2 0.016 14.9 0.8 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Phlebovirus_NSM PF07246.6 EAU88813.2 - 0.034 13.2 1.4 0.046 12.8 1.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Mnd1 PF03962.10 EAU88813.2 - 0.053 13.1 2.1 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 Mnd1 family Gaa1 PF04114.9 EAU88814.2 - 2e-43 148.8 18.6 6e-25 87.9 3.9 3.6 2 2 2 4 4 4 3 Gaa1-like, GPI transamidase component TAFII55_N PF04658.8 EAU88815.2 - 3.7e-53 179.3 1.1 3.7e-53 179.3 0.8 2.1 2 0 0 2 2 2 1 TAFII55 protein conserved region Astro_capsid PF03115.9 EAU88815.2 - 6 4.9 13.5 20 3.2 9.4 1.6 1 1 0 1 1 1 0 Astrovirus capsid protein precursor Tom37 PF10568.4 EAU88816.1 - 9.7e-14 51.3 0.1 2.3e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 EAU88816.1 - 3.5e-13 49.7 0.0 8.1e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Tom37 C-terminal domain GST_N_2 PF13409.1 EAU88816.1 - 0.059 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain NPR2 PF06218.6 EAU88817.2 - 4.2e-95 318.9 5.8 4e-71 239.9 0.8 3.1 2 1 1 3 3 3 3 Nitrogen permease regulator 2 NPR3 PF03666.8 EAU88817.2 - 0.0053 15.3 0.3 1.5 7.2 0.0 2.2 2 0 0 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 ThiF PF00899.16 EAU88818.1 - 3.5e-39 133.7 0.1 1.4e-38 131.7 0.0 1.8 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EAU88818.1 - 1e-25 89.0 0.4 1.8e-25 88.2 0.3 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EAU88818.1 - 9e-25 86.2 0.8 1.5e-24 85.5 0.6 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EAU88818.1 - 5.5e-18 64.0 2.1 5.5e-18 64.0 1.4 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EAU88818.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EAU88818.1 - 0.0047 16.4 0.8 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain Pyr_redox PF00070.22 EAU88818.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EAU88818.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA OGG_N PF07934.7 EAU88821.2 - 1e-31 109.2 0.0 1.6e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EAU88821.2 - 7.3e-17 61.6 0.0 1.7e-16 60.3 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EAU88821.2 - 0.062 13.0 0.2 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Transket_pyr PF02779.19 EAU88822.2 - 4.9e-40 136.9 0.1 7.2e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EAU88822.2 - 6.5e-27 93.9 0.0 4e-26 91.3 0.0 2.3 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.27 EAU88823.2 - 5e-15 54.7 14.4 0.0006 19.5 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EAU88823.2 - 0.00063 18.1 0.0 0.0019 16.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain DUF2636 PF11120.3 EAU88823.2 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Apc15p PF05841.6 EAU88824.1 - 2.8e-06 28.0 0.0 4.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Apc15p protein EMP24_GP25L PF01105.19 EAU88824.1 - 0.064 12.9 0.5 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MTHFR PF02219.12 EAU88825.2 - 9.6e-75 251.3 0.0 1.2e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ras PF00071.17 EAU88826.2 - 2e-59 199.6 0.5 2.6e-59 199.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU88826.2 - 1.2e-22 80.5 0.2 2.4e-22 79.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAU88826.2 - 2.3e-16 59.5 0.2 3e-16 59.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU88826.2 - 8.8e-08 31.7 0.5 6.2e-07 29.0 0.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAU88826.2 - 3.6e-07 29.5 0.7 4.7e-07 29.1 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAU88826.2 - 4.7e-07 29.2 0.1 1.2e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAU88826.2 - 4.3e-06 26.6 0.2 2e-05 24.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU88826.2 - 0.00022 20.5 0.6 0.011 15.0 0.4 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EAU88826.2 - 0.0054 16.4 0.0 0.016 14.9 0.0 1.6 1 1 1 2 2 2 1 Archaeal ATPase Dynamin_N PF00350.18 EAU88826.2 - 0.0075 16.1 0.1 0.86 9.4 0.0 2.4 2 1 0 2 2 2 1 Dynamin family PduV-EutP PF10662.4 EAU88826.2 - 0.025 14.0 2.1 0.26 10.7 1.5 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EAU88826.2 - 0.048 13.5 0.5 0.11 12.3 0.3 1.7 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 EAU88826.2 - 0.059 13.5 0.0 1.2 9.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain CPT PF07931.7 EAU88826.2 - 0.062 12.9 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 EAU88826.2 - 0.065 12.9 0.3 4.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TAP42 PF04177.7 EAU88827.1 - 7.2e-64 215.8 0.4 8.1e-64 215.7 0.3 1.0 1 0 0 1 1 1 1 TAP42-like family peroxidase PF00141.18 EAU88828.2 - 2.1e-24 86.2 0.0 3.6e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase POT1 PF02765.12 EAU88829.2 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Peptidase_M28 PF04389.12 EAU88833.1 - 2.8e-37 128.1 0.0 4.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 YebG PF07130.7 EAU88833.1 - 0.056 13.1 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 YebG protein Sybindin PF04099.7 EAU88834.1 - 2.4e-39 134.2 0.0 2.9e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EAU88834.1 - 5.6e-10 39.1 0.0 5.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HORMA PF02301.13 EAU88835.2 - 9.9e-21 74.1 0.0 1.2e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 HORMA domain HTH_25 PF13413.1 EAU88835.2 - 0.14 11.8 0.2 0.63 9.7 0.1 2.1 3 0 0 3 3 3 0 Helix-turn-helix domain HORMA PF02301.13 EAU88836.2 - 7.2e-13 48.4 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PFU PF09070.6 EAU88837.2 - 1.8e-43 147.2 0.4 3.5e-43 146.2 0.3 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EAU88837.2 - 5.2e-39 130.7 17.2 1e-08 34.7 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.6 EAU88837.2 - 1e-31 109.7 0.0 1.6e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EAU88837.2 - 0.00083 19.1 0.0 0.61 9.8 0.0 2.9 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region His_Phos_1 PF00300.17 EAU88838.2 - 1.3e-27 96.8 0.1 2.7e-27 95.8 0.1 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Rapamycin_bind PF08771.6 EAU88838.2 - 0.12 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Rapamycin binding domain RTC PF01137.16 EAU88839.2 - 5.4e-42 143.1 0.0 3.7e-31 107.6 0.0 2.0 1 1 1 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EAU88839.2 - 5.5e-33 113.0 0.0 8.2e-33 112.4 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain BMFP PF04380.8 EAU88841.2 - 0.0064 16.5 4.5 0.03 14.4 0.3 3.0 2 2 1 3 3 3 1 Membrane fusogenic activity DUF445 PF04286.7 EAU88841.2 - 0.0098 15.4 2.3 0.013 15.0 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Rnk_N PF14760.1 EAU88841.2 - 0.033 14.2 2.1 0.11 12.5 0.2 2.8 2 0 0 2 2 2 0 Rnk N-terminus DUF600 PF04634.7 EAU88841.2 - 0.079 12.9 1.8 0.16 12.0 0.2 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF600 Phage_GPO PF05929.6 EAU88841.2 - 0.091 12.0 2.3 0.1 11.8 0.2 1.8 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FliJ PF02050.11 EAU88841.2 - 0.15 12.1 4.3 0.92 9.5 0.0 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein Rabaptin PF03528.10 EAU88841.2 - 0.15 12.0 0.3 0.15 12.0 0.2 2.7 1 1 1 2 2 2 0 Rabaptin DUF1488 PF07369.6 EAU88841.2 - 0.16 11.8 0.8 0.55 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) DUF883 PF05957.8 EAU88841.2 - 0.31 11.4 2.3 4.8 7.6 0.0 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4303 PF14136.1 EAU88841.2 - 0.35 10.4 3.4 0.53 9.9 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) PhaP_Bmeg PF09602.5 EAU88841.2 - 0.36 10.6 5.8 7.9 6.2 0.7 2.9 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF4164 PF13747.1 EAU88841.2 - 0.44 10.7 7.3 0.79 9.8 0.3 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4164) DUF848 PF05852.6 EAU88841.2 - 0.99 9.2 7.4 0.76 9.6 1.2 2.7 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Kinetocho_Slk19 PF12709.2 EAU88841.2 - 1.2 9.2 6.6 15 5.7 0.3 3.3 3 0 0 3 3 3 0 Central kinetochore-associated FlgN PF05130.7 EAU88841.2 - 1.2 9.3 9.9 2.9 8.1 2.8 2.3 2 0 0 2 2 2 0 FlgN protein PEP-utilisers_N PF05524.8 EAU88841.2 - 1.7 8.4 4.6 12 5.7 0.1 3.0 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 EAU88841.2 - 4.6 6.7 11.2 24 4.4 4.5 2.9 2 1 0 2 2 2 0 IncA protein G-gamma PF00631.17 EAU88842.2 - 6.4e-24 83.4 0.0 7.2e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.17 EAU88843.2 - 2.2e-25 88.1 0.0 2.5e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 GGL domain Cu_bind_like PF02298.12 EAU88846.1 - 0.015 15.0 0.3 0.049 13.4 0.2 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain Myotub-related PF06602.9 EAU88847.2 - 2.5e-126 421.2 0.2 3.5e-126 420.7 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EAU88847.2 - 0.048 13.9 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EAU88847.2 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EAU88847.2 - 0.14 11.7 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain S-AdoMet_synt_C PF02773.11 EAU88848.1 - 4.4e-75 249.9 0.3 8.4e-75 249.0 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EAU88848.1 - 4.3e-50 168.6 0.0 7.6e-50 167.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EAU88848.1 - 2.9e-43 146.1 0.1 6.1e-43 145.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Amidinotransf PF02274.12 EAU88848.1 - 0.029 13.4 0.0 0.077 12.0 0.0 1.6 2 0 0 2 2 2 0 Amidinotransferase S-antigen PF05756.6 EAU88848.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 S-antigen protein GATase_2 PF00310.16 EAU88849.2 - 6.3e-26 90.9 0.2 6.1e-20 71.2 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EAU88849.2 - 1.7e-13 50.6 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EAU88849.2 - 2.7e-13 49.7 0.7 4.7e-13 48.9 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 EAU88849.2 - 5.9e-12 45.4 0.0 9.6e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EAU88849.2 - 3.7e-06 25.8 0.0 8.5e-06 24.6 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 EAU88849.2 - 0.074 12.5 0.1 14 5.2 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding dehydrogenase HIT PF01230.18 EAU88850.2 - 9.4e-25 87.0 0.0 1.4e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EAU88850.2 - 9e-08 32.3 0.0 1.4e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EAU88850.2 - 0.087 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Glyoxal_oxid_N PF07250.6 EAU88851.2 - 3.6e-50 170.3 0.0 1.3e-49 168.5 0.0 1.9 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EAU88851.2 - 2.6e-23 81.9 0.0 5e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EAU88851.2 - 2.2 8.1 4.9 63 3.4 0.0 4.1 5 0 0 5 5 5 0 Galactose oxidase, central domain Pkinase PF00069.20 EAU88854.1 - 6.2e-53 179.5 0.0 1.2e-52 178.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU88854.1 - 5.6e-47 159.9 0.0 1.1e-46 159.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 EAU88854.1 - 0.028 13.9 0.2 0.069 12.6 0.1 1.7 1 0 0 1 1 1 0 SAP domain Seadorna_VP7 PF07387.6 EAU88854.1 - 0.26 10.0 0.0 0.42 9.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3835 PF12927.2 EAU88855.2 - 7.9e-12 45.9 1.1 7.9e-12 45.9 0.8 4.8 4 1 0 4 4 4 2 Domain of unknown function (DUF3835) AAA PF00004.24 EAU88856.2 - 2.2e-07 31.1 0.1 1e-06 29.0 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EAU88856.2 - 4.2e-06 25.7 0.4 0.028 13.1 0.0 2.5 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EAU88856.2 - 1.1e-05 24.5 0.0 2.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EAU88856.2 - 0.00022 20.7 0.4 0.22 10.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 EAU88856.2 - 0.00024 20.7 0.0 0.00069 19.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EAU88856.2 - 0.0016 18.5 0.0 0.0096 16.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU88856.2 - 0.0028 17.6 0.2 0.046 13.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 EAU88856.2 - 0.014 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EAU88856.2 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EAU88856.2 - 0.028 14.3 0.0 0.083 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EAU88856.2 - 0.046 14.5 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU88856.2 - 0.048 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EAU88856.2 - 0.096 12.9 0.1 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EAU88856.2 - 0.1 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 EAU88856.2 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EAU88856.2 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 NTPase Hydrophobin PF01185.13 EAU88857.1 - 6.3e-18 64.9 7.9 8e-18 64.6 5.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Utp21 PF04192.7 EAU88858.2 - 4.5e-65 219.0 3.9 6.7e-65 218.4 2.7 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EAU88858.2 - 6.4e-21 73.4 8.7 2.5e-06 27.1 0.0 8.1 8 0 0 8 8 8 4 WD domain, G-beta repeat B12-binding_2 PF02607.12 EAU88858.2 - 0.012 15.6 0.3 0.045 13.7 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain PPPI_inhib PF14895.1 EAU88858.2 - 0.14 10.8 0.3 0.24 10.0 0.2 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor Nucleoporin_N PF08801.6 EAU88858.2 - 0.16 10.7 0.1 40 2.7 0.0 3.2 2 1 0 3 3 3 0 Nup133 N terminal like SRPRB PF09439.5 EAU88859.1 - 2e-25 89.0 0.0 2.8e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EAU88859.1 - 3.7e-13 49.1 0.0 4.9e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU88859.1 - 7.9e-08 31.7 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU88859.1 - 1.1e-06 28.5 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU88859.1 - 4e-06 26.3 0.0 0.00063 19.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EAU88859.1 - 0.00022 21.7 0.0 0.00039 20.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EAU88859.1 - 0.0062 15.2 0.0 1.9 7.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit ATP_bind_1 PF03029.12 EAU88859.1 - 0.019 14.5 0.1 0.081 12.4 0.0 1.8 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EAU88859.1 - 0.033 14.1 0.3 0.075 13.0 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EAU88859.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAU88859.1 - 0.1 12.1 0.1 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EAU88859.1 - 0.12 11.6 0.0 0.31 10.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MFS_1 PF07690.11 EAU88860.2 - 3.6e-29 101.5 32.2 2.3e-28 98.9 22.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1616 PF07760.6 EAU88860.2 - 0.0058 15.7 0.7 0.0058 15.7 0.5 1.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1616) EphA2_TM PF14575.1 EAU88860.2 - 0.15 12.4 0.1 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Clp1 PF06807.9 EAU88861.1 - 4.4e-19 69.0 0.0 2.4e-18 66.6 0.0 1.9 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EAU88861.1 - 1.7e-06 27.7 0.0 4.5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF1713 PF08213.6 EAU88862.2 - 0.0023 17.5 9.7 0.0033 16.9 6.7 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) UQ_con PF00179.21 EAU88863.2 - 7.5e-50 167.9 0.0 8.5e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAU88863.2 - 0.00048 19.8 0.0 0.00059 19.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAU88863.2 - 0.012 15.5 0.4 0.018 14.9 0.3 1.6 1 1 0 1 1 1 0 RWD domain DNA_methylase PF00145.12 EAU88864.2 - 2e-47 161.9 0.0 3.3e-46 157.9 0.0 2.3 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EAU88864.2 - 2.8e-16 59.3 0.0 1.2e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EAU88864.2 - 1.2e-12 47.7 0.0 2.3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain MCM PF00493.18 EAU88865.2 - 9e-137 455.2 0.1 3.5e-135 450.0 0.0 2.2 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EAU88865.2 - 1.9e-29 102.6 0.5 2.4e-28 99.0 0.5 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EAU88865.2 - 3.5e-08 33.2 0.0 7.2e-06 25.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EAU88865.2 - 4.8e-08 32.4 0.1 8.6e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 EAU88865.2 - 0.0022 18.3 0.8 0.0067 16.8 0.2 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAU88865.2 - 0.03 13.9 0.0 0.12 11.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_tranf_2_4 PF13704.1 EAU88865.2 - 0.042 14.1 1.2 22 5.4 0.0 3.3 2 1 0 2 2 2 0 Glycosyl transferase family 2 Sigma54_activat PF00158.21 EAU88865.2 - 0.082 12.3 0.0 0.51 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain NMT PF01233.14 EAU88866.1 - 3.2e-76 254.4 0.0 5.1e-76 253.7 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EAU88866.1 - 1.6e-67 226.5 0.0 9.8e-67 224.0 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EAU88866.1 - 3.7e-05 23.5 0.0 0.00021 21.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAU88866.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RuvA_C PF07499.8 EAU88866.1 - 0.25 11.5 0.7 2.6 8.2 0.5 2.2 1 1 0 1 1 1 0 RuvA, C-terminal domain KorB PF08535.5 EAU88868.2 - 0.025 14.7 0.0 0.056 13.6 0.0 1.6 1 1 1 2 2 2 0 KorB domain Toxin_19 PF08088.7 EAU88869.2 - 0.077 12.9 6.2 0.064 13.1 3.3 1.6 1 1 0 1 1 1 0 Conotoxin I-superfamily DUF1664 PF07889.7 EAU88874.1 - 0.093 12.5 0.0 4.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3416 PF11896.3 EAU88874.1 - 0.12 12.2 0.9 0.19 11.6 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3416) Pkinase PF00069.20 EAU88875.2 - 6.5e-06 25.4 0.0 2e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain F-box-like PF12937.2 EAU88876.2 - 2.3e-06 27.2 0.0 0.031 14.0 0.0 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EAU88876.2 - 0.085 12.5 0.3 13 5.6 0.0 3.0 2 0 0 2 2 2 0 F-box domain Hexapep PF00132.19 EAU88877.1 - 2.3e-06 26.8 16.1 0.052 13.0 0.2 4.2 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EAU88877.1 - 0.061 12.8 10.9 0.18 11.3 2.2 2.8 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.3 EAU88877.1 - 0.56 10.2 3.3 1.7 8.7 0.1 2.7 2 1 1 3 3 3 0 Bacteriocin subtilosin A Tim17 PF02466.14 EAU88878.1 - 0.051 13.6 1.0 0.25 11.4 0.2 2.0 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.27 EAU88879.1 - 9.5e-05 22.1 0.4 0.34 10.8 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EAU88879.1 - 0.003 17.7 4.2 0.25 11.6 0.2 4.1 4 0 0 4 4 4 1 PQQ-like domain PQQ PF01011.16 EAU88879.1 - 0.069 12.7 1.8 6.1 6.5 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat F-box PF00646.28 EAU88880.2 - 0.014 15.0 0.4 0.049 13.3 0.3 1.9 1 0 0 1 1 1 0 F-box domain WCCH PF03716.9 EAU88880.2 - 0.12 11.8 5.8 0.04 13.3 0.5 2.7 2 0 0 2 2 2 0 WCCH motif RdRP PF05183.7 EAU88888.2 - 2.2e-140 469.1 0.0 2.9e-140 468.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3492 PF11997.3 EAU88888.2 - 0.2 11.2 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) E1-E2_ATPase PF00122.15 EAU88889.2 - 4.8e-16 58.5 0.0 1.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EAU88889.2 - 1.1e-14 55.3 0.1 2.3e-09 37.9 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU88889.2 - 5.1e-13 49.6 0.2 4.1e-12 46.6 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAU88889.2 - 6.8e-11 41.9 0.0 1.9e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAU88889.2 - 3e-05 23.7 1.1 0.0037 16.8 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAU88889.2 - 0.079 13.1 0.1 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Septin PF00735.13 EAU88890.1 - 1.4e-113 378.6 0.8 1.7e-113 378.3 0.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EAU88890.1 - 2.7e-09 36.9 0.2 1.6e-08 34.4 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU88890.1 - 5.4e-08 32.2 0.0 1.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAU88890.1 - 4.5e-07 29.1 0.0 7.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EAU88890.1 - 6.2e-06 25.7 0.4 0.00045 19.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EAU88890.1 - 2.8e-05 23.9 0.4 0.12 12.2 0.1 2.5 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.22 EAU88890.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.7 EAU88890.1 - 0.001 18.3 0.2 0.0045 16.1 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 EAU88890.1 - 0.0015 18.0 0.1 0.002 17.5 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EAU88890.1 - 0.0021 16.9 0.1 0.0042 16.0 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 EAU88890.1 - 0.0022 16.9 0.0 0.0033 16.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EAU88890.1 - 0.0027 17.6 0.2 0.02 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EAU88890.1 - 0.0034 16.9 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family RuvB_N PF05496.7 EAU88890.1 - 0.0037 16.3 0.3 0.42 9.6 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EAU88890.1 - 0.0092 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EAU88890.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EAU88890.1 - 0.011 15.1 0.2 0.053 12.9 0.1 2.1 2 0 0 2 2 2 0 Ras family DEAD PF00270.24 EAU88890.1 - 0.029 13.8 0.0 0.045 13.2 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF815 PF05673.8 EAU88890.1 - 0.034 13.0 0.0 0.072 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EAU88890.1 - 0.043 13.9 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EAU88890.1 - 0.074 11.7 0.1 0.11 11.1 0.0 1.5 1 1 0 1 1 1 0 G-protein alpha subunit Miro PF08477.8 EAU88890.1 - 0.086 13.3 0.1 0.23 11.9 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein AAA_5 PF07728.9 EAU88890.1 - 0.13 11.9 0.2 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EAU88890.1 - 0.25 11.6 3.2 0.82 9.9 2.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU88890.1 - 0.26 11.5 3.0 13 6.1 0.1 2.5 2 1 0 2 2 2 0 AAA domain Aha1_N PF09229.6 EAU88891.2 - 2.2e-26 92.3 0.0 3.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EAU88891.2 - 1.1e-12 48.0 0.1 2.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EAU88891.2 - 1.2e-05 25.4 4.6 0.00065 19.8 0.3 2.2 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport DUF3235 PF11574.3 EAU88891.2 - 1.4 9.1 8.1 3.5 7.9 5.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Terpene_synth_C PF03936.11 EAU88892.1 - 8.3e-16 58.0 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain CAP_N PF01213.14 EAU88892.1 - 0.0049 16.2 0.2 0.0068 15.7 0.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal SPOB_ab PF14682.1 EAU88892.1 - 0.092 12.5 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Mito_fiss_reg PF05308.6 EAU88892.1 - 0.097 12.0 1.5 0.15 11.3 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3429 PF11911.3 EAU88893.2 - 6.4e-38 129.9 9.8 8.2e-38 129.5 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) TFIID_30kDa PF03540.8 EAU88894.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Gln-synt_C PF00120.19 EAU88896.2 - 4.1e-54 183.4 0.0 2.9e-53 180.6 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Pkinase PF00069.20 EAU88898.2 - 0.00037 19.7 0.0 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain SH3_9 PF14604.1 EAU88901.2 - 2.7e-14 52.4 0.0 4.5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAU88901.2 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAU88901.2 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1049 PF06305.6 EAU88901.2 - 0.05 13.0 0.9 0.11 11.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Chromo PF00385.19 EAU88903.2 - 1.4e-08 34.2 4.3 3.1e-08 33.1 2.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain F-box-like PF12937.2 EAU88904.2 - 3.8e-07 29.7 0.0 1.3e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EAU88904.2 - 0.19 12.0 1.6 43 4.9 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 EAU88907.2 - 1.4e-06 27.9 0.0 1.4e-06 27.9 0.0 2.6 4 0 0 4 4 4 1 F-box-like F-box PF00646.28 EAU88907.2 - 0.088 12.4 0.5 18 5.1 0.0 3.2 3 0 0 3 3 3 0 F-box domain tRNA_Me_trans PF03054.11 EAU88908.2 - 5.4e-105 350.8 0.0 6.2e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 EAU88908.2 - 0.018 13.9 0.1 0.6 8.9 0.0 2.6 2 1 0 2 2 2 0 NAD synthase ThiI PF02568.9 EAU88908.2 - 0.024 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EAU88908.2 - 0.066 12.7 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase CENP-C_C PF11699.3 EAU88909.1 - 1.6e-24 85.6 0.0 2.5e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EAU88909.1 - 6.3e-05 22.4 0.0 0.00017 20.9 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EAU88909.1 - 0.051 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Cupin Herpes_gE PF02480.11 EAU88910.1 - 0.00072 17.9 0.0 0.0011 17.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Adeno_E3_CR2 PF02439.10 EAU88910.1 - 0.017 14.6 0.7 0.026 14.0 0.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EAU88910.1 - 0.14 12.6 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SH3_1 PF00018.23 EAU88911.1 - 1.1e-11 43.8 0.7 1.4e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EAU88911.1 - 1.9e-09 36.9 0.6 0.00069 19.1 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EAU88911.1 - 9.6e-08 31.4 0.4 8.1e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EAU88911.1 - 0.0011 19.0 2.1 0.26 11.5 0.2 2.3 2 0 0 2 2 2 2 Bacterial SH3 domain LSM14 PF12701.2 EAU88913.1 - 1.9e-26 91.6 0.3 4.9e-26 90.3 0.0 1.9 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 EAU88913.1 - 1.9e-13 50.8 0.6 1.1e-12 48.3 0.0 2.2 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EAU88913.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Ataxin 2 SM domain TFIIA PF03153.8 EAU88913.1 - 1.1 9.0 22.2 1.7 8.4 15.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EAU88913.1 - 1.6 6.9 51.0 0.082 11.1 29.9 2.2 2 1 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 EAU88913.1 - 2.6 7.6 9.2 4.8 6.7 6.4 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit F-box-like PF12937.2 EAU88916.2 - 1.5e-06 27.8 1.1 3.5e-06 26.6 0.8 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU88916.2 - 0.24 11.0 2.2 3.1 7.5 0.2 3.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) COPI_assoc PF08507.5 EAU88919.1 - 3.1 7.4 10.9 0.72 9.5 4.1 2.0 1 1 1 2 2 2 0 COPI associated protein NAD_binding_10 PF13460.1 EAU88922.1 - 2.2e-09 37.5 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 EAU88922.1 - 0.0001 22.2 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EAU88922.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EAU88922.1 - 0.0018 17.3 0.0 0.0038 16.3 0.0 1.6 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.1 EAU88922.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EAU88922.1 - 0.1 11.8 0.2 0.24 10.6 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family Herpes_gE PF02480.11 EAU88923.2 - 0.036 12.3 0.0 0.051 11.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pol_alpha_B_N PF08418.5 EAU88923.2 - 0.22 11.0 0.5 0.35 10.3 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal EphA2_TM PF14575.1 EAU88924.2 - 0.019 15.3 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAA_hydrolase PF01557.13 EAU88925.2 - 3.3e-53 180.3 0.0 4.6e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CelD_N PF02927.9 EAU88925.2 - 0.037 14.2 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal ig-like domain of cellulase DUF2848 PF11010.3 EAU88925.2 - 0.048 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) Neur_chan_memb PF02932.11 EAU88926.2 - 0.00043 20.2 0.4 0.00059 19.7 0.3 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RELT PF12606.3 EAU88926.2 - 0.0018 17.3 0.0 0.0036 16.4 0.0 1.4 1 0 0 1 1 1 1 Tumour necrosis factor receptor superfamily member 19 DUF2269 PF10027.4 EAU88926.2 - 0.0026 17.5 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF1510 PF07423.6 EAU88926.2 - 0.027 13.8 1.3 0.058 12.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 EAU88926.2 - 0.067 12.6 1.8 0.15 11.5 1.2 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein Pox_A14 PF05767.7 EAU88926.2 - 0.07 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Calc_CGRP_IAPP PF00214.14 EAU88926.2 - 0.1 12.6 2.1 0.27 11.2 0.1 2.1 1 1 1 2 2 2 0 Calcitonin / CGRP / IAPP family MLANA PF14991.1 EAU88926.2 - 0.11 12.5 0.1 0.11 12.5 0.1 2.0 1 1 0 2 2 2 0 Protein melan-A DUF2500 PF10694.4 EAU88926.2 - 0.28 11.2 1.1 0.88 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) NVEALA PF14055.1 EAU88926.2 - 0.33 10.6 1.2 0.6 9.8 0.8 1.3 1 0 0 1 1 1 0 NVEALA protein EphA2_TM PF14575.1 EAU88926.2 - 1.6 9.1 5.4 2.1 8.7 0.9 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ctr PF04145.10 EAU88926.2 - 3 7.9 6.4 22 5.0 4.4 2.0 1 1 0 1 1 1 0 Ctr copper transporter family Shisa PF13908.1 EAU88926.2 - 5.6 7.1 5.9 71 3.5 4.1 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Hid1 PF12722.2 EAU88926.2 - 8.3 3.9 6.9 8.7 3.8 4.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TPP_enzyme_N PF02776.13 EAU88927.1 - 2.1e-56 190.1 0.0 5.3e-56 188.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EAU88927.1 - 1e-48 164.7 0.8 2e-47 160.6 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAU88927.1 - 4.6e-38 130.0 0.7 8.7e-38 129.1 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Herpes_gE PF02480.11 EAU88928.2 - 0.073 11.3 0.0 0.11 10.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EAU88928.2 - 0.099 12.3 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain DUF912 PF06024.7 EAU88928.2 - 0.19 11.8 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TPP_enzyme_N PF02776.13 EAU88931.2 - 8.3e-56 188.1 0.0 1.7e-55 187.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EAU88931.2 - 5.9e-46 155.8 0.6 1.6e-44 151.1 0.1 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EAU88931.2 - 4.3e-38 130.1 0.8 8.6e-38 129.1 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain F-box-like PF12937.2 EAU88933.1 - 5.4e-06 26.0 0.0 1.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EAU88933.1 - 0.21 11.3 2.5 0.23 11.2 0.1 2.3 3 0 0 3 3 3 0 Leucine rich repeat WD40 PF00400.27 EAU88935.2 - 6.6e-45 149.4 25.7 1.6e-08 34.0 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EAU88935.2 - 2.8e-14 52.5 2.6 6e-14 51.5 1.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU88935.2 - 2.4e-11 43.0 3.1 3.8e-11 42.3 1.1 2.1 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EAU88935.2 - 2e-06 26.2 3.4 0.061 11.4 0.0 4.2 2 1 2 4 4 4 4 Nucleoporin Nup120/160 DUF1258 PF06869.7 EAU88935.2 - 0.0016 17.5 0.2 0.032 13.3 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 EAU88935.2 - 0.049 13.0 0.2 3.3 7.1 0.0 3.1 1 1 0 2 2 2 0 PQQ-like domain Cellulase PF00150.13 EAU88936.2 - 3.9e-31 108.2 1.3 7.3e-31 107.4 0.9 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CesT PF05932.8 EAU88936.2 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family SNF2_N PF00176.18 EAU88937.1 - 1.3e-37 129.2 0.0 2.8e-33 114.9 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU88937.1 - 4.1e-06 26.5 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pam17 PF08566.5 EAU88938.1 - 1e-57 194.6 0.0 1.3e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DEAD PF00270.24 EAU88940.1 - 1.7e-42 144.7 0.0 2.8e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU88940.1 - 8.3e-21 73.6 0.0 1.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EAU88940.1 - 3.9e-20 71.1 0.4 7.5e-20 70.2 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.1 EAU88940.1 - 0.089 12.9 0.3 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF836 PF05768.9 EAU88941.2 - 4.9e-12 45.9 0.0 9.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-CCHC PF00098.18 EAU88941.2 - 0.0028 17.5 2.9 0.0048 16.7 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EAU88941.2 - 0.016 14.8 2.0 0.032 13.8 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Thioredoxin_3 PF13192.1 EAU88941.2 - 0.098 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain SAPS PF04499.10 EAU88942.2 - 3.8e-122 408.3 0.1 6.7e-122 407.5 0.0 1.4 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Adap_comp_sub PF00928.16 EAU88943.2 - 1.6e-79 266.6 0.0 2e-79 266.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAU88943.2 - 0.0035 17.0 0.2 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Adenylsucc_synt PF00709.16 EAU88944.1 - 3.7e-163 543.0 0.0 4.2e-163 542.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase MCD PF05292.6 EAU88944.1 - 0.23 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase (MCD) COX16 PF14138.1 EAU88945.2 - 1e-28 99.2 0.2 1.4e-28 98.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 RicinB_lectin_2 PF14200.1 EAU88947.1 - 3.5e-62 207.3 25.7 7.9e-20 71.1 0.3 8.2 2 1 6 8 8 8 7 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU88947.1 - 1e-27 96.6 13.0 2.7e-14 53.2 0.1 6.0 2 2 3 6 6 6 4 Ricin-type beta-trefoil lectin domain Fascin PF06268.8 EAU88947.1 - 0.027 14.5 0.0 19 5.3 0.0 3.6 2 1 1 3 3 3 0 Fascin domain FGF PF00167.13 EAU88947.1 - 0.045 13.5 0.0 10 5.9 0.0 3.7 4 1 1 5 5 5 0 Fibroblast growth factor RicinB_lectin_2 PF14200.1 EAU88949.1 - 8e-57 190.1 21.9 6.7e-16 58.5 0.2 7.4 2 2 5 7 7 7 7 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU88949.1 - 2.8e-20 72.6 18.6 4.2e-11 42.9 1.0 4.4 3 1 2 5 5 5 4 Ricin-type beta-trefoil lectin domain DUF925 PF06042.6 EAU88949.1 - 0.019 14.5 1.3 0.16 11.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF925) DUF4594 PF15266.1 EAU88953.1 - 0.0014 18.7 19.0 0.0014 18.7 13.1 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4594) Rhabdo_ncap PF00945.13 EAU88953.1 - 0.42 9.1 3.0 0.55 8.7 2.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Zip PF02535.17 EAU88953.1 - 0.5 9.3 2.3 0.6 9.0 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.8 EAU88953.1 - 0.55 8.9 16.2 0.86 8.2 11.2 1.2 1 0 0 1 1 1 0 Paf1 DUF3608 PF12257.3 EAU88954.2 - 3.2e-60 203.4 0.0 4.8e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EAU88954.2 - 2.1e-15 56.1 0.0 5.2e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YajC PF02699.10 EAU88954.2 - 0.4 10.4 0.2 0.75 9.5 0.2 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit RicinB_lectin_2 PF14200.1 EAU88955.1 - 5e-53 177.8 26.5 2.7e-15 56.6 0.6 8.3 3 2 5 8 8 8 8 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU88955.1 - 1.8e-22 79.6 16.3 1.3e-11 44.6 0.8 4.2 4 1 0 4 4 4 2 Ricin-type beta-trefoil lectin domain zf-C4H2 PF10146.4 EAU88957.1 - 7.8e-06 26.0 0.2 9.2e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Vps5 PF09325.5 EAU88957.1 - 0.011 14.9 2.1 0.016 14.4 1.5 1.2 1 0 0 1 1 1 0 Vps5 C terminal like DUF2205 PF10224.4 EAU88957.1 - 0.022 14.2 2.9 0.071 12.6 1.7 2.0 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Surface_antigen PF11054.3 EAU88957.1 - 0.049 13.0 0.1 0.071 12.4 0.1 1.2 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen TBPIP PF07106.8 EAU88957.1 - 0.41 10.1 4.3 1 8.9 2.9 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1690 PF07956.6 EAU88957.1 - 0.44 10.5 6.1 1.3 8.9 2.7 2.1 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) DivIC PF04977.10 EAU88957.1 - 0.74 9.3 3.0 2.2 7.8 1.0 2.3 1 1 1 2 2 2 0 Septum formation initiator AT_hook PF02178.14 EAU88957.1 - 1.2 9.0 8.1 2.7 7.9 5.6 1.6 1 0 0 1 1 1 0 AT hook motif Acetyltransf_1 PF00583.19 EAU88958.2 - 5.6e-12 45.5 0.1 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EAU88958.2 - 7.6e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EAU88958.2 - 0.00048 20.2 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU88958.2 - 0.0047 16.7 0.3 0.0092 15.8 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAU88958.2 - 0.029 14.5 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAU88958.2 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.2 EAU88960.2 - 1.7e-06 27.6 0.0 4.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU88960.2 - 0.0012 18.3 0.0 0.0049 16.4 0.0 2.1 1 1 0 1 1 1 1 F-box domain ATP-grasp_2 PF08442.5 EAU88960.2 - 0.2 11.0 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Choline_transpo PF04515.7 EAU88963.2 - 2.2e-20 72.6 8.4 3e-20 72.2 4.4 2.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter F-box-like PF12937.2 EAU88964.1 - 2.3e-09 36.8 0.1 6.8e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like Cyclin_N PF00134.18 EAU88966.2 - 1e-12 47.7 0.0 2.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EAU88966.2 - 3.7e-10 40.3 2.3 1.6e-09 38.3 0.6 2.7 2 1 0 2 2 2 1 Cyclin Tropomyosin_1 PF12718.2 EAU88967.2 - 0.049 13.4 0.2 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 EAU88967.2 - 0.16 12.3 0.0 0.59 10.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EAU88967.2 - 0.3 10.6 2.2 0.64 9.5 0.1 2.5 3 0 0 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 EAU88967.2 - 1.1 9.1 6.6 0.81 9.5 3.0 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tet_JBP PF12851.2 EAU88974.2 - 9.9e-06 24.9 0.0 2.4e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily DUF791 PF05631.9 EAU88977.2 - 0.016 13.9 0.2 0.02 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF791) Lipase_GDSL_2 PF13472.1 EAU88978.2 - 2.5e-10 40.7 0.1 3.3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU88978.2 - 1.1e-09 38.4 0.0 1.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Zn_Tnp_IS1595 PF12760.2 EAU88979.2 - 0.00011 21.8 0.2 0.00027 20.6 0.2 1.6 1 0 0 1 1 1 1 Transposase zinc-ribbon domain TerY-C PF15616.1 EAU88979.2 - 0.027 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zinc_ribbon_2 PF13240.1 EAU88979.2 - 0.042 13.3 0.6 0.068 12.6 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EAU88979.2 - 0.13 11.5 0.2 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain WD40 PF00400.27 EAU88980.2 - 9.1e-08 31.7 8.6 0.015 15.1 0.0 6.3 5 1 0 5 5 5 2 WD domain, G-beta repeat YL1 PF05764.8 EAU88980.2 - 0.11 12.0 3.7 0.19 11.3 2.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EAU88980.2 - 1.1 7.0 8.5 1.6 6.5 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family OTCace_N PF02729.16 EAU88984.1 - 3.4e-44 149.9 0.0 4.7e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EAU88984.1 - 1.2e-43 148.7 0.0 1.5e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF2273 PF10031.4 EAU88985.1 - 0.0079 15.7 1.3 0.011 15.2 0.9 1.2 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) DUF4448 PF14610.1 EAU88985.1 - 0.044 13.2 0.2 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Shisa PF13908.1 EAU88985.1 - 1 9.5 0.0 1 9.5 0.0 3.3 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 EAU88986.2 - 0.16 11.2 2.1 0.36 10.0 1.4 1.5 1 0 0 1 1 1 0 Tetraspanin family Neurensin PF14927.1 EAU88986.2 - 7.6 5.9 5.9 2.3 7.5 0.0 3.0 3 1 1 4 4 4 0 Neurensin Neurensin PF14927.1 EAU88987.1 - 0.44 9.9 5.2 3.1 7.1 0.1 3.5 4 0 0 4 4 4 0 Neurensin Glypican PF01153.14 EAU88988.2 - 0.16 10.5 4.7 1.8 7.1 0.1 2.4 1 1 0 2 2 2 0 Glypican Hemagglutinin PF00509.13 EAU88988.2 - 0.89 7.6 0.8 1.4 6.9 0.5 1.2 1 0 0 1 1 1 0 Haemagglutinin Phage_lysis PF03245.8 EAU88988.2 - 4.4 7.3 12.9 0.033 14.1 0.5 3.3 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein DUF1104 PF06518.6 EAU88995.1 - 0.26 11.4 0.0 0.48 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) AOX PF01786.12 EAU88999.2 - 2.8e-76 255.5 0.0 3.5e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase p450 PF00067.17 EAU89003.2 - 6.6e-69 232.6 0.0 1e-68 231.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AIG1 PF04548.11 EAU89004.2 - 4.4e-09 35.7 0.0 7.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EAU89004.2 - 7.9e-06 25.8 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU89004.2 - 4.6e-05 23.2 0.2 0.21 11.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.13 EAU89004.2 - 0.00057 18.9 0.0 0.00083 18.4 0.0 1.2 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 EAU89004.2 - 0.0015 17.7 0.1 0.0077 15.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EAU89004.2 - 0.012 14.4 0.0 0.035 12.9 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EAU89004.2 - 0.028 14.7 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.12 EAU89004.2 - 0.053 13.0 0.4 3.5 7.0 0.1 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EAU89004.2 - 0.071 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein GBP PF02263.14 EAU89004.2 - 0.072 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_33 PF13671.1 EAU89004.2 - 0.085 12.7 0.1 0.19 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EAU89004.2 - 0.11 11.9 0.1 0.28 10.6 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase PF00069.20 EAU89005.1 - 2.5e-05 23.5 0.0 4.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU89005.1 - 0.089 12.5 0.2 0.63 9.7 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EAU89005.1 - 0.092 11.8 0.3 0.15 11.0 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EAU89005.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU89006.2 - 8.7e-06 25.0 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EAU89006.2 - 0.019 14.0 0.1 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU89006.2 - 0.023 14.4 0.2 0.63 9.7 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EAU89006.2 - 0.17 10.9 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU89007.2 - 3.9e-06 26.1 0.0 6.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU89007.2 - 0.017 14.8 0.3 0.32 10.7 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EAU89007.2 - 0.099 11.6 0.1 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 EAU89008.1 - 2.3e-10 40.0 0.2 6e-10 38.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU89008.1 - 0.00086 18.8 0.1 0.0028 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EAU89008.1 - 0.057 13.1 0.9 0.15 11.7 0.6 1.6 1 1 0 1 1 1 0 F-box-like domain RicinB_lectin_2 PF14200.1 EAU89009.2 - 4.8e-10 39.7 0.0 1.6e-09 38.0 0.0 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF2024 PF09630.5 EAU89013.2 - 0.075 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Tetraspannin PF00335.15 EAU89016.2 - 1.2e-12 47.6 8.0 1.7e-12 47.0 5.6 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3278 PF11683.3 EAU89016.2 - 0.01 15.7 0.2 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) SIM_C PF06621.7 EAU89017.1 - 0.081 12.4 1.8 0.11 12.0 1.3 1.1 1 0 0 1 1 1 0 Single-minded protein C-terminus Tyrosinase PF00264.15 EAU89028.1 - 4.1e-39 135.0 0.0 8.4e-39 134.0 0.0 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF1697 PF08002.6 EAU89028.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) RRM_1 PF00076.17 EAU89029.2 - 9.7e-26 89.2 0.1 1.4e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89029.2 - 4.1e-18 65.1 0.0 5.2e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU89029.2 - 1e-15 57.3 0.1 1.2e-06 28.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAU89029.2 - 0.00077 19.1 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 Calcipressin PF04847.7 EAU89029.2 - 0.00088 18.9 0.9 0.014 15.0 0.1 2.3 2 0 0 2 2 2 1 Calcipressin HNH_2 PF13391.1 EAU89030.1 - 3e-06 26.8 0.0 5.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease RicinB_lectin_2 PF14200.1 EAU89034.1 - 1.2e-32 112.4 1.2 1.8e-15 57.1 0.0 3.0 3 1 1 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU89034.1 - 0.0045 17.0 0.8 1 9.4 0.6 3.5 3 1 0 3 3 3 1 Ricin-type beta-trefoil lectin domain tRNA_anti-codon PF01336.20 EAU89034.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RicinB_lectin_2 PF14200.1 EAU89036.2 - 1.3e-26 93.0 0.0 3e-13 50.0 0.0 3.0 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU89036.2 - 0.002 18.1 0.0 16 5.5 0.0 3.5 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain Tyrosinase PF00264.15 EAU89037.2 - 6.1e-19 69.0 2.0 7e-11 42.7 0.1 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase RicinB_lectin_2 PF14200.1 EAU89039.1 - 7.8e-12 45.4 0.1 6.8e-08 32.8 0.0 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like HNH_2 PF13391.1 EAU89040.2 - 0.03 14.0 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease F-box-like PF12937.2 EAU89041.1 - 4.8e-09 35.8 3.1 5.8e-09 35.5 0.9 2.2 2 0 0 2 2 2 1 F-box-like DUF3716 PF12511.3 EAU89042.1 - 5.9 6.5 8.5 69 3.1 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) BTB PF00651.26 EAU89045.2 - 4e-07 30.0 0.0 2.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain CAP_GLY PF01302.20 EAU89045.2 - 3.6e-06 26.5 0.7 0.00019 21.0 0.3 3.2 2 1 0 2 2 2 1 CAP-Gly domain Nop14 PF04147.7 EAU89045.2 - 1.6 6.5 16.7 2.6 5.8 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family Helicase_C PF00271.26 EAU89052.2 - 9.9e-14 50.9 0.0 2.5e-07 30.4 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DUF2812 PF11193.3 EAU89073.2 - 0.066 13.3 0.4 13 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) Pkinase PF00069.20 EAU89074.2 - 6.9e-06 25.4 0.0 9.7e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU89074.2 - 0.0028 17.4 0.2 0.33 10.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EAU89074.2 - 0.012 14.6 0.1 0.024 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EAU89074.2 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU89075.2 - 6.6e-06 25.4 0.0 1.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU89075.2 - 0.017 14.8 0.2 0.28 10.8 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EAU89075.2 - 0.017 14.1 0.2 0.033 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EAU89075.2 - 0.15 11.0 0.0 0.33 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase BRCT PF00533.21 EAU89078.2 - 3.6e-23 81.5 0.0 4.5e-11 42.7 0.0 6.0 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EAU89078.2 - 3.7e-22 77.9 1.2 1.6e-15 56.7 0.2 4.2 4 0 0 4 4 4 3 twin BRCT domain Catalase PF00199.14 EAU89079.1 - 4.1e-145 483.2 0.5 5.7e-145 482.8 0.4 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EAU89079.1 - 4.9e-10 39.1 0.1 8.7e-10 38.3 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive TPR_2 PF07719.12 EAU89084.2 - 0.019 14.8 0.6 0.047 13.6 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU89084.2 - 0.062 12.9 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAU89084.2 - 0.12 13.1 0.3 0.52 11.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAU89084.2 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 TPR repeat MMR_HSR1 PF01926.18 EAU89090.2 - 9.7e-08 31.9 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU89090.2 - 1e-06 28.6 0.1 0.039 13.7 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.11 EAU89090.2 - 2.2e-05 23.6 0.6 0.00018 20.6 0.1 2.4 2 1 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EAU89090.2 - 6.8e-05 22.1 0.5 0.0011 18.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EAU89090.2 - 0.00075 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter IIGP PF05049.8 EAU89090.2 - 0.0026 16.6 0.2 0.017 13.9 0.0 2.1 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Septin PF00735.13 EAU89090.2 - 0.0038 16.2 0.0 0.01 14.8 0.0 1.7 2 0 0 2 2 2 1 Septin Miro PF08477.8 EAU89090.2 - 0.012 16.1 0.1 0.032 14.7 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 EAU89090.2 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.22 EAU89090.2 - 0.033 13.6 0.0 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAU89090.2 - 0.082 12.0 0.1 0.55 9.3 0.1 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 EAU89090.2 - 0.086 12.2 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EAU89090.2 - 0.11 12.1 0.1 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 GBP PF02263.14 EAU89090.2 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Lyase_1 PF00206.15 EAU89090.2 - 0.13 11.4 0.1 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Lyase AAA_33 PF13671.1 EAU89090.2 - 0.13 12.1 0.2 0.5 10.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EAU89090.2 - 0.14 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rubella_E1 PF05748.6 EAU89093.2 - 0.01 14.5 0.0 0.019 13.5 0.0 1.4 1 0 0 1 1 1 1 Rubella membrane glycoprotein E1 CBF PF03914.12 EAU89096.1 - 7e-41 139.4 0.8 1.7e-40 138.1 0.5 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Euplotes_phero PF05842.6 EAU89096.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Phage_integrase PF00589.17 EAU89100.1 - 9.2e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF4328 PF14219.1 EAU89101.2 - 0.086 12.1 5.9 0.8 8.9 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) WD40 PF00400.27 EAU89102.2 - 3.9e-66 216.7 19.8 2.5e-11 42.9 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EAU89102.2 - 7.4e-22 77.3 5.6 1.3e-21 76.5 3.9 1.4 1 0 0 1 1 1 1 Tup N-terminal Nucleoporin_N PF08801.6 EAU89102.2 - 0.00017 20.5 2.9 0.3 9.7 0.0 3.8 2 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.6 EAU89102.2 - 0.00029 20.5 0.0 0.26 10.9 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Phage_lysis PF03245.8 EAU89102.2 - 0.00091 19.2 0.7 0.0019 18.1 0.5 1.5 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein Cytochrom_D1 PF02239.11 EAU89102.2 - 0.0035 15.6 0.5 0.021 13.1 0.1 2.4 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 EAU89102.2 - 0.017 13.2 9.0 0.051 11.7 0.0 4.0 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EAU89102.2 - 0.16 11.4 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain IL8 PF00048.15 EAU89102.2 - 0.21 11.5 1.6 0.72 9.8 1.1 1.8 1 1 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like Proteasome_A_N PF10584.4 EAU89102.2 - 1.9 7.9 6.5 50 3.3 0.1 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature CENP-F_leu_zip PF10473.4 EAU89103.2 - 0.00028 20.7 36.7 0.00062 19.6 8.0 5.6 1 1 5 6 6 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EAU89103.2 - 0.0006 19.0 28.6 0.017 14.3 2.7 3.8 1 1 3 4 4 4 3 Reovirus sigma C capsid protein GAS PF13851.1 EAU89103.2 - 0.00079 18.6 11.3 0.00079 18.6 7.8 6.3 2 1 3 6 6 6 1 Growth-arrest specific micro-tubule binding Lebercilin PF15619.1 EAU89103.2 - 0.001 18.5 20.9 0.001 18.5 14.5 4.5 3 1 1 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease DUF869 PF05911.6 EAU89103.2 - 0.0011 17.3 10.3 0.0011 17.3 7.1 3.7 2 1 0 3 3 2 1 Plant protein of unknown function (DUF869) DUF1664 PF07889.7 EAU89103.2 - 0.0016 18.2 5.7 0.0016 18.2 4.0 5.3 2 1 2 5 5 5 2 Protein of unknown function (DUF1664) DUF2959 PF11172.3 EAU89103.2 - 0.004 16.9 11.8 0.004 16.9 8.2 3.3 1 1 1 3 3 3 1 Protein of unknown function (DUF2959) DUF3450 PF11932.3 EAU89103.2 - 0.0058 15.9 7.0 0.0058 15.9 4.9 4.8 1 1 3 5 5 5 1 Protein of unknown function (DUF3450) DUF948 PF06103.6 EAU89103.2 - 0.048 13.5 0.5 0.048 13.5 0.3 4.6 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.4 EAU89103.2 - 0.1 12.2 0.1 0.1 12.2 0.1 3.8 2 2 2 5 5 5 0 Apolipoprotein O BRE1 PF08647.6 EAU89103.2 - 0.11 12.4 38.7 0.12 12.3 0.6 4.9 2 1 1 4 4 4 0 BRE1 E3 ubiquitin ligase WEMBL PF05701.6 EAU89103.2 - 0.35 9.2 62.4 0.15 10.4 17.4 2.4 1 1 1 2 2 2 0 Weak chloroplast movement under blue light GLE1 PF07817.8 EAU89103.2 - 1.6 7.6 6.3 0.56 9.0 1.3 2.5 1 1 2 3 3 3 0 GLE1-like protein Spc7 PF08317.6 EAU89103.2 - 1.6 7.3 49.6 0.91 8.1 7.4 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein Fib_alpha PF08702.5 EAU89103.2 - 1.6 8.8 31.6 0.3 11.2 2.7 4.8 2 1 4 6 6 5 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 EAU89103.2 - 1.8 8.3 64.8 0.13 11.9 8.3 6.0 2 1 3 6 6 6 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.6 EAU89103.2 - 3.6 6.9 16.2 0.27 10.5 4.1 3.7 1 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF812 PF05667.6 EAU89103.2 - 7 5.0 51.0 0.11 10.9 7.2 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF812) HrpB7 PF09486.5 EAU89103.2 - 7.6 6.4 61.0 0.03 14.2 12.9 5.3 2 1 4 6 6 6 0 Bacterial type III secretion protein (HrpB7) Peptidase_C13 PF01650.13 EAU89109.2 - 1.7e-34 119.3 0.6 2.2e-34 118.8 0.0 1.4 2 0 0 2 2 2 1 Peptidase C13 family Alginate_lyase2 PF08787.6 EAU89109.2 - 0.16 11.5 1.6 0.16 11.5 0.2 1.6 2 0 0 2 2 2 0 Alginate lyase HCNGP PF07818.8 EAU89110.1 - 1.6e-12 47.3 0.3 2.9e-12 46.4 0.2 1.5 1 0 0 1 1 1 1 HCNGP-like protein Macoilin PF09726.4 EAU89110.1 - 2.4 6.3 5.6 3.2 5.9 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 EAU89110.1 - 3.6 6.7 6.3 5.2 6.1 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF959 PF06121.9 EAU89110.1 - 4.5 6.8 8.8 4 7.0 1.2 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF959) Ank_2 PF12796.2 EAU89111.2 - 3.6e-38 129.7 0.0 5.5e-12 45.8 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAU89111.2 - 7.5e-31 104.3 0.2 0.0014 18.3 0.0 7.4 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EAU89111.2 - 9.5e-28 95.6 3.6 3.4e-08 33.4 0.0 6.2 3 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU89111.2 - 5.5e-22 77.7 0.2 3.3e-05 24.2 0.0 5.8 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU89111.2 - 3.7e-20 69.9 0.1 0.11 12.8 0.0 8.2 7 0 0 7 7 7 6 Ankyrin repeat Pkinase PF00069.20 EAU89112.2 - 3.5e-06 26.3 0.1 6.2e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU89112.2 - 0.00043 20.0 1.8 0.0049 16.6 0.3 2.8 3 1 1 4 4 4 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU89112.2 - 0.0035 16.9 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EAU89112.2 - 0.087 11.8 0.1 0.21 10.5 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2 PF00152.15 EAU89113.1 - 1.3e-64 218.0 0.0 6.7e-53 179.6 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAU89113.1 - 5.9e-09 35.6 0.2 1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain LSM PF01423.17 EAU89114.2 - 1.1e-18 66.4 0.6 1.6e-18 66.0 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAU89114.2 - 0.022 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 EAU89114.2 - 0.028 14.1 0.1 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BPL_C PF02237.12 EAU89114.2 - 0.041 13.5 0.3 0.086 12.5 0.2 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain API5 PF05918.6 EAU89114.2 - 2.9 6.2 9.3 3.9 5.8 6.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Kinesin PF00225.18 EAU89115.1 - 4.4e-94 314.9 0.3 4.4e-94 314.9 0.2 1.6 2 0 0 2 2 2 1 Kinesin motor domain TPR_2 PF07719.12 EAU89115.1 - 0.0033 17.2 0.1 0.0086 15.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU89115.1 - 0.005 16.5 0.1 0.013 15.2 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU89115.1 - 0.008 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU89115.1 - 0.057 14.0 0.1 0.057 14.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat EIF_2_alpha PF07541.7 EAU89116.1 - 3.8e-35 120.0 0.0 7.9e-35 119.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EAU89116.1 - 6.8e-12 45.3 0.7 1.3e-11 44.4 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain ANAPC15 PF15243.1 EAU89116.1 - 0.91 9.6 4.9 0.32 11.0 0.2 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 15 zf-CCHC PF00098.18 EAU89127.2 - 0.017 15.0 3.4 0.017 15.0 2.4 2.1 2 0 0 2 2 2 0 Zinc knuckle Lsr2 PF11774.3 EAU89128.2 - 0.13 12.2 3.4 3 7.8 0.6 2.6 2 0 0 2 2 2 0 Lsr2 PIF1 PF05970.9 EAU89145.1 - 1.8e-76 257.4 0.0 2.3e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 EAU89145.1 - 1.2e-08 34.5 0.9 6.1e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EAU89145.1 - 1.4e-08 34.5 0.0 2.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EAU89145.1 - 3.1e-06 26.4 0.0 4.8e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EAU89145.1 - 9.3e-05 22.4 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EAU89145.1 - 0.00071 20.3 0.0 0.0015 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAU89145.1 - 0.0027 17.2 0.1 0.053 13.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 EAU89145.1 - 0.006 14.4 0.0 1 7.0 0.0 2.1 2 0 0 2 2 2 2 Helicase T2SE PF00437.15 EAU89145.1 - 0.01 14.7 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EAU89145.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EAU89145.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EAU89145.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.1 EAU89145.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EAU89145.1 - 0.04 12.6 0.0 0.18 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EAU89145.1 - 0.044 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EAU89145.1 - 0.057 13.1 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 EAU89145.1 - 0.071 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EAU89145.1 - 0.098 12.2 0.0 0.53 9.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU89145.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EAU89145.1 - 0.17 11.3 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EAU89145.1 - 0.23 10.4 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase DUF4337 PF14235.1 EAU89147.1 - 0.01 15.7 5.4 0.01 15.7 3.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Phage_TAC PF06222.6 EAU89147.1 - 0.013 15.0 2.1 0.023 14.2 1.5 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone DivIC PF04977.10 EAU89147.1 - 0.35 10.3 2.1 0.3 10.5 0.3 1.8 2 0 0 2 2 2 0 Septum formation initiator Protocadherin PF08374.6 EAU89147.1 - 0.55 9.8 3.6 0.92 9.0 2.5 1.4 1 0 0 1 1 1 0 Protocadherin CENP-H PF05837.7 EAU89147.1 - 5.2 7.2 8.3 0.84 9.8 2.9 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) F-box-like PF12937.2 EAU89151.2 - 3.7e-06 26.5 0.0 9.2e-06 25.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU89152.1 - 4.2e-09 35.9 0.2 1.2e-08 34.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like NMD3 PF04981.8 EAU89153.1 - 1.3e-73 247.0 0.2 1.8e-73 246.5 0.1 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 EAU89153.1 - 0.0021 17.8 2.8 0.0044 16.8 0.7 2.3 2 0 0 2 2 2 1 Double zinc ribbon NinF PF05810.7 EAU89153.1 - 0.055 13.2 1.1 0.26 11.1 0.3 2.3 2 0 0 2 2 2 0 NinF protein Rpr2 PF04032.11 EAU89153.1 - 0.12 12.2 1.6 14 5.5 0.1 2.8 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GFA PF04828.9 EAU89153.1 - 0.73 9.8 3.7 2 8.4 0.3 2.9 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme WSC PF01822.14 EAU89154.1 - 2.6e-16 59.2 3.3 8.5e-16 57.6 2.1 2.0 2 0 0 2 2 2 1 WSC domain UQ_con PF00179.21 EAU89155.1 - 2.6e-49 166.2 0.0 3e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAU89155.1 - 3.5e-08 33.2 0.0 8.5e-08 32.0 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EAU89155.1 - 0.14 12.0 0.1 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 RWD domain F-box-like PF12937.2 EAU89156.2 - 6.4e-11 41.7 0.9 1.5e-10 40.6 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU89156.2 - 0.022 14.3 6.1 0.039 13.6 0.4 3.0 3 0 0 3 3 3 0 F-box domain DivIC PF04977.10 EAU89156.2 - 0.071 12.6 0.3 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 Septum formation initiator PVL_ORF50 PF07768.6 EAU89156.2 - 0.13 12.3 0.8 0.23 11.4 0.5 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family TMF_DNA_bd PF12329.3 EAU89156.2 - 0.17 11.7 5.2 0.28 11.0 3.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 EAU89156.2 - 0.29 10.9 2.8 0.54 10.0 2.0 1.4 1 0 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 EAU89156.2 - 0.32 10.5 2.6 0.52 9.8 1.8 1.2 1 0 0 1 1 1 0 IncA protein DMPK_coil PF08826.5 EAU89156.2 - 0.35 10.8 4.5 0.71 9.8 3.1 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like APG6 PF04111.7 EAU89156.2 - 0.43 9.5 2.3 0.64 9.0 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4315 PF14193.1 EAU89156.2 - 1.2 9.1 6.4 7.1 6.6 0.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) DUF4131 PF13567.1 EAU89159.2 - 1 8.7 3.3 1.2 8.4 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) F-box-like PF12937.2 EAU89160.1 - 0.00044 19.9 0.1 0.0018 17.9 0.1 2.1 1 1 0 1 1 1 1 F-box-like YopJ PF03421.11 EAU89160.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase CBM_21 PF03370.8 EAU89161.2 - 4.9e-15 55.4 0.6 1.1e-14 54.3 0.4 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Alpha-amylase PF00128.19 EAU89161.2 - 9e-05 22.0 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain UDP-g_GGTase PF06427.6 EAU89163.2 - 3.9e-47 160.3 0.0 6.7e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EAU89163.2 - 4e-08 32.8 0.1 7.3e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Doppel PF11466.3 EAU89164.1 - 0.029 13.9 0.7 0.054 13.0 0.5 1.4 1 0 0 1 1 1 0 Prion-like protein Doppel CsbD PF05532.7 EAU89165.1 - 3.4e-19 68.2 13.8 3.1e-11 42.7 1.4 2.1 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 EAU89165.1 - 0.026 14.6 0.7 0.041 13.9 0.1 1.7 2 1 0 2 2 2 0 Heat shock protein 9/12 MucBP PF06458.7 EAU89165.1 - 0.11 13.1 3.2 0.15 12.6 2.2 1.2 1 0 0 1 1 1 0 MucBP domain CsbD PF05532.7 EAU89166.1 - 4.3e-17 61.5 13.3 3e-10 39.6 1.8 2.3 1 1 1 2 2 2 2 CsbD-like DEAD PF00270.24 EAU89171.1 - 6.5e-40 136.3 0.2 1.3e-39 135.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU89171.1 - 1.9e-23 82.1 0.1 1.9e-23 82.1 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EAU89171.1 - 0.012 14.7 0.2 0.037 13.0 0.1 1.8 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit KCl_Cotrans_1 PF03522.10 EAU89172.2 - 0.14 11.7 3.2 0.25 10.9 2.2 1.4 1 0 0 1 1 1 0 K-Cl Co-transporter type 1 (KCC1) COesterase PF00135.23 EAU89173.2 - 7.5e-71 239.4 0.0 9.7e-52 176.3 0.0 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU89173.2 - 3.9e-05 23.3 0.0 8.5e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU89173.2 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1769 PF08588.5 EAU89174.1 - 3.9e-15 55.5 0.0 9.9e-15 54.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Hamartin PF04388.7 EAU89174.1 - 4.7 5.7 6.2 5.8 5.4 4.3 1.1 1 0 0 1 1 1 0 Hamartin protein Glyco_hydro_61 PF03443.9 EAU89176.2 - 5.5e-32 111.3 0.0 8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4470 PF14737.1 EAU89177.2 - 7.9e-25 86.5 0.0 1.5e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) YebG PF07130.7 EAU89178.1 - 0.11 12.2 5.0 0.67 9.6 0.3 2.9 3 0 0 3 3 3 0 YebG protein FlaC_arch PF05377.6 EAU89178.1 - 0.22 11.4 2.4 0.34 10.8 0.6 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Leucyl-specific PF14795.1 EAU89178.1 - 0.25 11.2 5.4 1.1 9.2 0.3 3.5 3 0 0 3 3 3 0 Leucine-tRNA synthetase-specific domain NPV_P10 PF05531.7 EAU89178.1 - 2.2 8.6 7.0 1.3 9.2 1.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein G-alpha PF00503.15 EAU89179.2 - 6.5e-128 426.7 0.0 7.3e-128 426.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU89179.2 - 4.4e-11 42.3 0.0 2.8e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EAU89179.2 - 0.0059 16.1 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU89179.2 - 0.032 14.2 0.3 0.086 12.8 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EAU89179.2 - 0.049 13.1 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EAU89179.2 - 0.056 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EAU89179.2 - 0.086 12.2 0.0 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Cu-oxidase PF00394.17 EAU89180.2 - 3.4e-40 137.5 0.0 2.4e-39 134.8 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU89180.2 - 2.4e-29 101.4 4.1 2.4e-26 91.7 0.0 3.7 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU89180.2 - 3.4e-28 97.8 3.1 2.2e-24 85.5 0.3 3.6 3 1 0 3 3 3 2 Multicopper oxidase DUF4470 PF14737.1 EAU89182.2 - 1.5e-22 79.2 0.0 2.3e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) WD40 PF00400.27 EAU89183.1 - 1.4e-67 221.3 19.1 4.8e-10 38.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EAU89183.1 - 1.1e-19 70.3 7.1 2.3e-19 69.3 5.0 1.6 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EAU89183.1 - 0.044 12.0 0.2 0.12 10.6 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain ORF6C PF10552.4 EAU89183.1 - 0.086 12.5 1.1 0.17 11.5 0.8 1.4 1 0 0 1 1 1 0 ORF6C domain V_ATPase_I PF01496.14 EAU89183.1 - 0.79 7.4 0.8 1.3 6.7 0.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EAU89183.1 - 8.1 5.9 9.5 0.25 10.8 0.3 2.2 2 0 0 2 2 2 0 IncA protein Cu-oxidase PF00394.17 EAU89184.2 - 9.2e-40 136.1 0.0 8e-39 133.0 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU89184.2 - 1.3e-20 73.3 1.6 3.2e-18 65.5 0.2 2.9 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU89184.2 - 2.8e-12 46.4 0.9 1.3e-09 37.7 0.2 2.8 2 0 0 2 2 2 2 Multicopper oxidase adh_short_C2 PF13561.1 EAU89185.2 - 8.5e-18 65.0 0.0 2.1e-13 50.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU89185.2 - 2.6e-15 56.7 4.1 2.5e-07 30.7 0.6 2.6 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAU89185.2 - 0.0011 18.6 0.8 0.0028 17.3 0.1 1.9 1 1 1 2 2 2 1 KR domain MMR_HSR1 PF01926.18 EAU89187.2 - 0.1 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AIG1 PF04548.11 EAU89187.2 - 0.12 11.4 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 EAU89188.2 - 1.2e-09 38.0 0.1 2.1e-09 37.3 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU89188.2 - 2.3e-09 37.3 1.4 2.9e-06 27.1 0.3 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EAU89188.2 - 5.3e-07 28.9 0.0 6.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAU89188.2 - 3.5e-06 26.2 0.0 6.8e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EAU89188.2 - 0.00013 21.0 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_29 PF13555.1 EAU89188.2 - 0.00014 21.3 0.2 0.00036 19.9 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EAU89188.2 - 0.00041 20.6 0.0 0.00067 19.9 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EAU89188.2 - 0.00098 19.1 0.3 0.0024 17.8 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EAU89188.2 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 EAU89188.2 - 0.0022 17.5 0.1 0.0039 16.6 0.1 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EAU89188.2 - 0.0022 18.3 0.2 0.041 14.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU89188.2 - 0.0025 17.5 0.2 0.007 16.0 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 EAU89188.2 - 0.0029 17.3 0.1 0.011 15.5 0.0 1.8 1 1 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 EAU89188.2 - 0.0036 18.1 0.6 0.0088 16.8 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EAU89188.2 - 0.0056 16.2 0.2 0.0095 15.5 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU89188.2 - 0.0057 16.7 0.0 0.017 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EAU89188.2 - 0.0081 15.8 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EAU89188.2 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU89188.2 - 0.012 15.2 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 EAU89188.2 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EAU89188.2 - 0.015 14.7 0.1 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EAU89188.2 - 0.022 13.6 0.1 0.037 12.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Adeno_IVa2 PF02456.10 EAU89188.2 - 0.029 13.0 0.1 0.043 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein FeoB_N PF02421.13 EAU89188.2 - 0.031 13.5 0.2 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.1 EAU89188.2 - 0.04 14.2 0.1 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EAU89188.2 - 0.045 13.4 0.1 0.08 12.6 0.1 1.3 1 0 0 1 1 1 0 NTPase Gtr1_RagA PF04670.7 EAU89188.2 - 0.057 12.5 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EAU89188.2 - 0.059 12.9 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EAU89188.2 - 0.06 13.5 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA PF00004.24 EAU89188.2 - 0.063 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.16 EAU89188.2 - 0.071 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Guanylate kinase AAA_25 PF13481.1 EAU89188.2 - 0.084 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAU89188.2 - 0.093 12.6 0.3 1.4 8.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EAU89188.2 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EAU89188.2 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EAU89188.2 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EAU89188.2 - 0.18 10.5 0.7 0.35 9.5 0.3 1.6 1 1 1 2 2 2 0 ArgK protein Herpes_Helicase PF02689.9 EAU89188.2 - 0.19 9.4 0.0 0.26 8.9 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF367 PF04034.8 EAU89189.2 - 3.9e-45 152.5 0.0 5.2e-45 152.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EAU89189.2 - 8.2e-14 50.9 0.2 1.3e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF1213 PF06740.7 EAU89189.2 - 0.72 10.0 9.5 1.1 9.3 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) MRP-L27 PF09809.4 EAU89190.1 - 2.6e-09 36.6 0.2 4e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF3760 PF12586.3 EAU89190.1 - 0.0099 15.6 0.0 0.26 11.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3760) Ricin_B_lectin PF00652.17 EAU89191.1 - 5.9e-25 87.6 7.5 1.1e-24 86.8 5.2 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EAU89191.1 - 6.2e-19 68.3 6.5 5.3e-10 39.6 0.2 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 EAU89191.1 - 0.23 10.8 4.9 4.9 6.5 0.1 3.0 2 1 0 3 3 3 0 Cytolethal distending toxin A/C family MMR_HSR1 PF01926.18 EAU89192.1 - 1e-08 35.1 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU89192.1 - 3.6e-07 30.1 0.4 0.028 14.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Septin PF00735.13 EAU89192.1 - 3.7e-06 26.1 0.0 5.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Septin AIG1 PF04548.11 EAU89192.1 - 4.3e-06 25.9 0.0 5.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAU89192.1 - 0.0002 20.5 0.0 0.0005 19.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EAU89192.1 - 0.038 13.8 0.1 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain IIGP PF05049.8 EAU89192.1 - 0.057 12.2 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EAU89193.2 - 2e-07 30.9 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU89193.2 - 3.5e-05 23.6 0.6 0.16 11.7 0.1 2.2 1 1 1 2 2 2 2 Dynamin family Septin PF00735.13 EAU89193.2 - 0.00088 18.3 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 EAU89193.2 - 0.001 18.2 2.3 0.0031 16.7 0.3 2.3 2 1 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EAU89193.2 - 0.0011 19.3 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.11 EAU89193.2 - 0.0019 17.3 0.2 0.0055 15.8 0.1 1.8 2 1 0 2 2 2 1 AIG1 family T2SE PF00437.15 EAU89193.2 - 0.0037 16.2 0.1 0.0059 15.5 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activat PF00158.21 EAU89193.2 - 0.0052 16.2 0.0 0.009 15.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EAU89193.2 - 0.0062 16.0 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF87 PF01935.12 EAU89193.2 - 0.0066 16.2 0.2 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EAU89193.2 - 0.0083 16.9 0.4 0.012 16.4 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EAU89193.2 - 0.01 16.1 0.7 0.017 15.4 0.5 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAU89193.2 - 0.029 13.8 0.3 0.074 12.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 EAU89193.2 - 0.03 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EAU89193.2 - 0.05 13.4 0.1 0.089 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU89193.2 - 0.061 13.6 0.0 0.081 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EAU89193.2 - 0.081 12.3 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 EAU89197.2 - 0.0014 18.5 0.4 0.0091 15.9 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAU89197.2 - 0.02 14.0 0.4 2 7.5 0.3 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EAU89197.2 - 0.02 14.6 0.1 0.072 12.9 0.1 1.9 1 1 1 2 2 2 0 Dynamin family DUF3333 PF11812.3 EAU89197.2 - 0.082 12.9 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) AAA_29 PF13555.1 EAU89197.2 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PAS_9 PF13426.1 EAU89202.1 - 1.2e-28 99.5 0.0 5.3e-19 68.5 0.0 3.7 3 1 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EAU89202.1 - 3.3e-15 55.9 0.7 6.2e-06 26.2 0.0 5.5 5 1 0 5 5 5 3 PAS fold PAS PF00989.19 EAU89202.1 - 4e-15 55.5 0.0 7.3e-07 28.9 0.0 4.5 3 2 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EAU89202.1 - 2.8e-08 33.7 0.0 5e-05 23.2 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.1 EAU89202.1 - 3.2e-07 30.2 1.6 3.9e-05 23.5 0.0 3.8 4 1 0 4 4 4 1 PAS domain PAS_8 PF13188.1 EAU89202.1 - 0.00033 20.4 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 PAS domain HemX PF04375.9 EAU89202.1 - 0.8 8.2 4.0 1.7 7.1 2.8 1.5 1 0 0 1 1 1 0 HemX Striatin PF08232.7 EAU89202.1 - 1.1 9.5 4.4 0.47 10.7 0.1 2.4 3 0 0 3 3 3 0 Striatin family Ribosomal_L16 PF00252.13 EAU89203.1 - 7.8e-34 116.2 0.0 9.9e-34 115.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e EthD PF07110.6 EAU89204.1 - 0.026 15.4 0.0 0.033 15.1 0.0 1.3 1 0 0 1 1 1 0 EthD domain PfkB PF00294.19 EAU89206.2 - 4.5e-30 104.8 0.0 5.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase zf-CCCH PF00642.19 EAU89207.1 - 0.0019 17.8 10.2 0.0038 16.8 2.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAU89207.1 - 0.4 10.7 11.7 0.14 12.2 2.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type MMR_HSR1 PF01926.18 EAU89208.1 - 2e-21 76.1 0.0 3.3e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EAU89208.1 - 9.3e-18 63.9 0.1 4.6e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AIG1 PF04548.11 EAU89208.1 - 2.9e-17 62.4 0.0 8e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.18 EAU89208.1 - 9.2e-12 45.1 8.4 0.021 14.6 0.1 4.3 2 2 2 4 4 4 4 Dynamin family Septin PF00735.13 EAU89208.1 - 1.7e-10 40.3 0.0 0.00026 20.1 0.0 2.3 2 0 0 2 2 2 2 Septin ABC_tran PF00005.22 EAU89208.1 - 5.5e-09 36.4 0.0 0.00038 20.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter Miro PF08477.8 EAU89208.1 - 9e-09 35.8 0.0 0.0037 17.7 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EAU89208.1 - 1.3e-08 35.0 0.0 0.0053 16.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain IIGP PF05049.8 EAU89208.1 - 1.5e-08 33.8 2.9 0.00083 18.2 0.1 2.4 2 1 0 2 2 2 2 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EAU89208.1 - 3.4e-07 30.4 0.1 0.037 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EAU89208.1 - 1e-05 25.1 0.1 0.08 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 EAU89208.1 - 1.3e-05 24.5 1.2 0.15 11.6 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain GBP PF02263.14 EAU89208.1 - 2.3e-05 23.5 0.1 0.022 13.7 0.0 2.2 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_24 PF13479.1 EAU89208.1 - 4.8e-05 23.0 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain FeoB_N PF02421.13 EAU89208.1 - 0.00012 21.3 0.2 0.14 11.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Arch_ATPase PF01637.13 EAU89208.1 - 0.00013 21.7 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase MobB PF03205.9 EAU89208.1 - 0.00015 21.4 2.2 0.26 11.0 0.5 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EAU89208.1 - 0.00026 20.4 0.0 0.38 10.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EAU89208.1 - 0.00034 20.2 0.2 0.67 9.5 0.0 2.4 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 EAU89208.1 - 0.0004 20.5 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 EAU89208.1 - 0.00044 19.2 0.3 0.21 10.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EAU89208.1 - 0.00045 20.5 4.3 0.24 11.7 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EAU89208.1 - 0.00056 19.8 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EAU89208.1 - 0.00059 19.3 2.0 0.048 13.1 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EAU89208.1 - 0.0011 18.5 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Ras PF00071.17 EAU89208.1 - 0.0011 18.4 0.2 0.21 10.9 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_17 PF13207.1 EAU89208.1 - 0.0015 19.3 0.0 1.4 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 EAU89208.1 - 0.0038 15.9 0.8 1.5 7.4 0.1 2.2 2 0 0 2 2 2 2 Adenovirus IVa2 protein GTP_EFTU PF00009.22 EAU89208.1 - 0.0042 16.5 1.2 3.6 6.9 0.1 3.6 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EAU89208.1 - 0.0054 17.0 0.0 4.8 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EAU89208.1 - 0.0093 16.1 0.0 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EAU89208.1 - 0.01 15.0 0.1 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EAU89208.1 - 0.011 15.4 0.6 1.2 8.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EAU89208.1 - 0.017 14.0 0.1 3.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.12 EAU89208.1 - 0.02 14.6 3.8 0.94 9.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EAU89208.1 - 0.042 13.3 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EAU89208.1 - 0.061 13.0 1.0 3 7.5 0.0 2.5 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 EAU89208.1 - 0.065 12.7 0.6 6.1 6.3 0.0 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EAU89208.1 - 0.08 12.0 0.3 12 4.8 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin IstB_IS21 PF01695.12 EAU89208.1 - 0.11 11.9 0.5 7.9 5.8 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DAP3 PF10236.4 EAU89208.1 - 0.11 11.4 0.3 0.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 EAU89208.1 - 0.16 11.8 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EAU89208.1 - 0.21 10.4 0.3 13 4.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.17 EAU89208.1 - 0.21 11.0 0.3 40 3.5 0.1 3.1 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain DUF4131 PF13567.1 EAU89209.2 - 2.1 7.7 7.9 0.24 10.7 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MMR_HSR1 PF01926.18 EAU89210.1 - 5.3e-09 36.0 0.0 9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU89210.1 - 3.8e-05 22.8 0.0 7.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAU89210.1 - 9.8e-05 21.5 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAU89210.1 - 0.0018 18.3 0.0 0.0041 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EAU89210.1 - 0.003 17.3 0.3 0.079 12.7 0.3 2.4 1 1 0 2 2 2 1 Dynamin family ABC_tran PF00005.22 EAU89210.1 - 0.0031 17.8 0.0 0.006 16.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EAU89210.1 - 0.0038 16.7 0.1 0.013 14.9 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 EAU89210.1 - 0.0098 14.8 0.0 0.064 12.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) cobW PF02492.14 EAU89210.1 - 0.01 15.3 0.0 0.023 14.1 0.1 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 EAU89210.1 - 0.016 14.1 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_22 PF13401.1 EAU89210.1 - 0.02 15.0 0.0 0.076 13.1 0.0 2.0 3 0 0 3 3 1 0 AAA domain Arch_ATPase PF01637.13 EAU89210.1 - 0.025 14.2 0.0 0.12 12.0 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 EAU89210.1 - 0.054 14.3 0.1 0.14 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EAU89210.1 - 0.066 13.7 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 EAU89210.1 - 0.067 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EAU89210.1 - 0.094 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EAU89210.1 - 0.12 11.4 0.0 1.2 8.1 0.0 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Zeta_toxin PF06414.7 EAU89210.1 - 0.12 11.4 0.1 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF1720 PF08226.6 EAU89211.1 - 0.035 14.1 40.4 41 4.3 17.3 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1720) Peptidase_C48 PF02902.14 EAU89215.2 - 2.3e-12 47.0 0.0 4.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF1572 PF07609.6 EAU89217.1 - 0.14 11.7 0.6 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) APO_RNA-bind PF05634.6 EAU89218.2 - 0.019 14.1 2.1 0.028 13.6 1.5 1.2 1 0 0 1 1 1 0 APO RNA-binding Cauli_VI PF01693.11 EAU89221.1 - 5.6e-09 35.8 0.4 9.3e-09 35.1 0.3 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin HET PF06985.6 EAU89223.2 - 7.6e-06 26.1 0.4 0.0055 16.8 0.0 2.6 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Transferase PF02458.10 EAU89225.1 - 0.11 10.9 0.0 0.59 8.5 0.0 2.0 1 1 0 1 1 1 0 Transferase family CsbD PF05532.7 EAU89228.1 - 9.4e-05 22.0 3.9 0.00021 20.9 2.7 1.6 1 0 0 1 1 1 1 CsbD-like Mid2 PF04478.7 EAU89229.1 - 0.033 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3455 PF11937.3 EAU89230.1 - 2.7e-21 76.3 0.1 3.4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Oxidored_FMN PF00724.15 EAU89231.1 - 6.4e-68 229.2 0.0 8.5e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EAU89231.1 - 0.023 13.5 0.0 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) DnaJ PF00226.26 EAU89235.1 - 2.1e-22 78.6 1.1 3e-21 74.9 0.3 2.8 2 1 0 2 2 2 1 DnaJ domain Peptidase_S49 PF01343.13 EAU89235.1 - 0.025 14.3 0.2 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 Borrelia_P83 PF05262.6 EAU89235.1 - 0.11 10.7 13.6 0.14 10.3 9.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1754 PF08555.5 EAU89237.1 - 0.0069 16.9 1.2 0.0069 16.9 0.8 1.7 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) TA0956 PF11513.3 EAU89239.2 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 Nup96 PF12110.3 EAU89241.1 - 3.4e-53 180.6 0.0 1.3e-52 178.6 0.0 2.1 2 1 0 2 2 2 1 Nuclear protein 96 Daxx PF03344.10 EAU89241.1 - 0.026 13.0 10.2 0.035 12.5 7.1 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 EAU89241.1 - 1.1 7.5 17.8 1.7 6.9 12.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EAU89241.1 - 8.3 4.1 22.5 13 3.5 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_53 PF07745.8 EAU89242.1 - 1.5e-91 306.6 0.1 1.7e-91 306.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 EAU89242.1 - 1.4e-05 24.4 1.4 2.3e-05 23.7 0.8 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LRR_6 PF13516.1 EAU89243.1 - 5.5e-08 32.0 9.5 0.75 10.0 0.3 5.8 6 0 0 6 6 6 5 Leucine Rich repeat HABP4_PAI-RBP1 PF04774.10 EAU89243.1 - 0.022 15.2 1.7 0.036 14.5 1.2 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family LRR_4 PF12799.2 EAU89243.1 - 0.41 10.3 8.4 1.5 8.5 0.3 3.7 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) Treacle PF03546.9 EAU89243.1 - 0.44 9.2 2.3 0.64 8.7 1.6 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle EMP24_GP25L PF01105.19 EAU89245.1 - 2.9e-37 128.1 0.0 3.3e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ycf4 PF02392.11 EAU89245.1 - 0.08 12.2 0.1 0.23 10.7 0.1 1.7 2 0 0 2 2 2 0 Ycf4 MBA1 PF07961.6 EAU89246.2 - 8.9e-11 41.0 0.0 1.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EAU89246.2 - 0.0068 16.3 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Tim44-like domain SspK PF08176.7 EAU89246.2 - 0.1 12.5 0.3 0.79 9.7 0.0 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein K family DUF2076 PF09849.4 EAU89247.2 - 0.031 14.3 0.6 0.035 14.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zinc-ribbons_6 PF07191.7 EAU89247.2 - 0.033 13.9 3.7 0.046 13.5 2.6 1.2 1 0 0 1 1 1 0 zinc-ribbons CHCH PF06747.8 EAU89247.2 - 0.054 13.4 5.0 0.21 11.5 2.9 2.0 1 1 1 2 2 2 0 CHCH domain Histone_HNS PF00816.16 EAU89249.1 - 1.6 9.2 9.7 0.38 11.2 0.2 2.6 3 0 0 3 3 3 0 H-NS histone family TMF_DNA_bd PF12329.3 EAU89249.1 - 3.9 7.3 13.2 0.15 11.9 2.4 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding C2 PF00168.25 EAU89251.1 - 2.9e-59 196.8 8.1 1.1e-17 63.6 0.3 4.9 5 0 0 5 5 5 4 C2 domain DUF2404 PF10296.4 EAU89251.1 - 0.024 14.7 0.0 0.11 12.6 0.0 2.1 1 1 1 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) Plexin_cytopl PF08337.7 EAU89251.1 - 0.082 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain E1-E2_ATPase PF00122.15 EAU89252.1 - 1.3e-56 191.2 0.1 1.3e-56 191.2 0.1 2.6 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 EAU89252.1 - 2.8e-25 89.9 0.4 5.4e-25 89.0 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAU89252.1 - 5.6e-15 54.5 0.1 1.1e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EAU89252.1 - 1.5e-14 54.6 0.1 4.2e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAU89252.1 - 3.5e-06 26.7 0.1 0.00028 20.5 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF3650 PF12368.3 EAU89252.1 - 1.2 8.6 3.2 0.47 9.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) Fungal_trans PF04082.13 EAU89253.2 - 5.3e-36 123.8 0.1 8.9e-36 123.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EAU89255.1 - 5.5e-29 100.9 28.5 5.1e-18 64.9 4.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAU89255.1 - 7.6e-06 24.5 4.2 7.6e-06 24.5 2.9 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein DUF1228 PF06779.9 EAU89255.1 - 2.5 8.1 8.4 7.2 6.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EAU89256.1 - 3.8e-26 91.6 39.3 3.7e-17 62.0 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.19 EAU89257.2 - 1.6e-26 92.2 0.0 2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAU89257.2 - 1.6e-06 28.0 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EAU89258.1 - 3e-22 78.4 0.2 5e-22 77.8 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAU89258.1 - 3.2e-06 27.0 1.1 5.8e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EAU89258.1 - 0.00023 21.4 0.0 0.00043 20.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EAU89258.1 - 0.023 13.3 2.8 0.029 13.0 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 EAU89258.1 - 0.027 15.0 0.5 0.037 14.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 EAU89258.1 - 0.061 12.7 0.1 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Trypan_glycop PF00913.14 EAU89258.1 - 0.27 10.0 7.2 0.39 9.5 4.8 1.4 1 1 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) PWI PF01480.12 EAU89259.2 - 1.9e-27 95.1 0.1 3.1e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 PWI domain Glyco_hydro_61 PF03443.9 EAU89260.1 - 4.7e-57 193.3 0.2 7.5e-57 192.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAU89260.1 - 7.1e-11 41.5 17.0 7.1e-11 41.5 11.8 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.9 EAU89261.1 - 6.7e-54 182.9 0.2 1.1e-53 182.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EAU89261.1 - 3.7e-11 42.4 16.6 3.7e-11 42.4 11.5 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Bestrophin PF01062.16 EAU89262.2 - 4.3e-50 170.3 10.0 1.9e-31 109.1 0.1 2.8 2 1 1 3 3 3 2 Bestrophin, RFP-TM, chloride channel WBP-1 PF11669.3 EAU89263.2 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 EVC2_like PF12297.3 EAU89263.2 - 0.2 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Glyco_hydro_61 PF03443.9 EAU89264.2 - 3.5e-51 174.1 0.4 5.3e-51 173.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cupredoxin_1 PF13473.1 EAU89264.2 - 0.16 11.8 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Glyco_transf_90 PF05686.7 EAU89266.2 - 4.6e-09 35.4 0.1 1.1e-06 27.6 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 TPR_7 PF13176.1 EAU89267.1 - 7.8e-11 40.9 0.0 0.062 13.1 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAU89267.1 - 9.2e-10 38.3 0.1 0.042 13.7 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAU89267.1 - 4.4e-06 26.2 0.1 0.24 11.0 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAU89267.1 - 7.5e-06 25.4 0.0 1.9 8.5 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 EAU89267.1 - 9.8e-06 25.3 0.0 0.18 11.6 0.0 3.5 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 EAU89267.1 - 0.0077 15.7 0.1 3.5 7.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU89267.1 - 0.0096 16.5 0.0 6 7.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU89267.1 - 0.018 15.6 0.6 22 6.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HMG_box PF00505.14 EAU89271.2 - 6.8e-11 42.2 0.3 1.4e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU89271.2 - 0.01 16.2 0.1 0.019 15.3 0.1 1.4 1 0 0 1 1 1 0 HMG-box domain Syndecan PF01034.15 EAU89271.2 - 0.22 11.1 0.0 0.42 10.2 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain COX14 PF14880.1 EAU89272.2 - 0.17 11.5 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Sec62 PF03839.11 EAU89274.1 - 5.8e-51 173.0 0.0 8.6e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 DUF1517 PF07466.6 EAU89274.1 - 0.3 10.0 1.6 13 4.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) DUF3413 PF11893.3 EAU89274.1 - 2.5 6.9 6.9 3.7 6.3 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) HAD_2 PF13419.1 EAU89275.1 - 6.1e-20 72.1 0.0 1.7e-13 51.1 0.0 3.3 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Yeast-kill-tox PF09207.6 EAU89278.1 - 3.3 8.1 10.9 3.7 8.0 1.1 2.3 1 1 1 2 2 2 0 Yeast killer toxin MFS_1 PF07690.11 EAU89279.2 - 2.5e-39 134.9 43.8 2.5e-39 134.9 30.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU89279.2 - 2.3e-06 26.4 0.5 2.3e-06 26.4 0.3 3.8 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_3 PF05977.8 EAU89279.2 - 0.00057 18.1 7.0 0.0011 17.2 4.9 1.5 1 1 0 1 1 1 1 Transmembrane secretion effector FPN1 PF06963.7 EAU89279.2 - 0.016 13.6 0.9 6.1 5.1 0.0 3.0 3 0 0 3 3 3 0 Ferroportin1 (FPN1) EXS PF03124.9 EAU89280.2 - 4.5e-72 242.9 25.2 3.6e-71 239.9 17.5 2.0 1 1 0 1 1 1 1 EXS family SPX PF03105.14 EAU89280.2 - 2.1e-48 165.5 0.0 6.9e-48 163.7 0.0 1.8 1 1 0 1 1 1 1 SPX domain Glyco_transf_22 PF03901.12 EAU89281.2 - 6.9e-59 199.9 16.6 8.8e-59 199.5 11.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Latexin PF06907.7 EAU89281.2 - 0.097 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Latexin Vps16_N PF04841.8 EAU89282.2 - 2.3e-86 289.9 0.0 3e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EAU89282.2 - 7.7e-75 251.7 0.0 2.5e-74 250.0 0.0 1.7 1 1 0 1 1 1 1 Vps16, C-terminal region RmlD_sub_bind PF04321.12 EAU89284.2 - 6.6e-57 192.5 0.0 8.1e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EAU89284.2 - 8.6e-22 77.7 0.0 1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EAU89284.2 - 1.3e-06 27.5 0.0 9e-05 21.5 0.0 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EAU89284.2 - 6e-05 23.1 0.0 7.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EAU89284.2 - 0.0012 17.7 0.0 0.022 13.7 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Eno-Rase_NADH_b PF12242.3 EAU89284.2 - 0.0041 16.8 0.7 0.0068 16.1 0.5 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DapB_N PF01113.15 EAU89284.2 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PRY PF13765.1 EAU89285.2 - 0.14 11.7 0.2 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 SPRY-associated domain LSM PF01423.17 EAU89286.1 - 9.1e-15 53.9 0.1 1.1e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 EAU89286.1 - 0.025 14.1 0.0 0.036 13.6 0.0 1.2 1 1 0 1 1 1 0 Repressor of phase-1 flagellin TPT PF03151.11 EAU89287.2 - 9.2e-22 77.3 10.7 9.2e-22 77.3 7.4 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EAU89287.2 - 0.0019 17.2 17.3 0.0027 16.6 4.2 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EAU89287.2 - 0.091 12.8 30.4 0.017 15.1 6.5 2.6 2 1 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 EAU89287.2 - 0.51 10.5 21.8 0.078 13.1 3.4 2.8 2 1 1 3 3 3 0 Multidrug resistance efflux transporter DUF155 PF02582.9 EAU89288.2 - 3.1e-46 157.4 0.0 5.5e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF4283 PF14111.1 EAU89288.2 - 0.085 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) CAF-1_p150 PF11600.3 EAU89288.2 - 7.1 5.9 18.3 0.29 10.4 4.3 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Condensation PF00668.15 EAU89289.2 - 0.15 10.9 0.0 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Condensation domain DUF2106 PF09879.4 EAU89291.1 - 0.086 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) F-box PF00646.28 EAU89291.1 - 0.12 12.0 0.1 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 F-box domain DUF4194 PF13835.1 EAU89291.1 - 0.14 11.6 1.4 0.44 9.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) Sec20 PF03908.8 EAU89292.1 - 4.6e-18 64.7 8.0 1.9e-17 62.7 2.5 2.7 2 0 0 2 2 2 2 Sec20 HisKA_3 PF07730.8 EAU89292.1 - 7.9 6.9 9.1 2.8 8.3 0.6 2.9 2 1 0 2 2 2 0 Histidine kinase Cnd3 PF12719.2 EAU89293.2 - 5.5e-69 232.4 5.8 5.5e-69 232.4 4.0 2.3 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EAU89293.2 - 1.3e-09 38.1 3.9 5.5e-07 29.7 0.2 4.2 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EAU89293.2 - 3.5e-06 26.6 0.6 1.4 9.1 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 EAU89293.2 - 0.0046 17.3 1.8 0.0046 17.3 1.2 3.8 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 EAU89293.2 - 0.016 15.0 0.1 0.22 11.3 0.0 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EAU89293.2 - 0.029 14.3 0.5 0.54 10.2 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Sod_Fe_C PF02777.13 EAU89294.1 - 9.2e-36 121.9 0.1 1.7e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EAU89294.1 - 2.3e-32 111.0 2.9 5.4e-32 109.8 1.4 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 EAU89294.1 - 0.072 12.9 8.4 0.44 10.4 2.6 2.4 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain RNase_PH PF01138.16 EAU89296.2 - 1.1e-31 109.8 0.0 1.7e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAU89296.2 - 0.00034 20.4 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 p450 PF00067.17 EAU89297.2 - 6.1e-70 236.0 0.0 7e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.6 EAU89298.1 - 3e-14 52.4 0.4 4e-14 52.0 0.3 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) p450 PF00067.17 EAU89299.1 - 8.1e-71 238.9 0.0 1e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MscS_porin PF12795.2 EAU89299.1 - 0.0043 16.4 0.1 0.0065 15.8 0.0 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Transket_pyr PF02779.19 EAU89300.2 - 6.5e-61 204.9 0.0 9.2e-61 204.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EAU89300.2 - 2.3e-28 98.8 0.0 3.3e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component F-box PF00646.28 EAU89301.2 - 8.5e-05 22.1 0.0 0.00025 20.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU89301.2 - 0.00036 20.2 0.1 0.0008 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Ferric_reduct PF01794.14 EAU89303.2 - 1.5e-14 54.1 15.4 4.3e-14 52.6 10.7 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EAU89303.2 - 3e-07 30.4 0.6 0.0043 16.9 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EAU89303.2 - 1.9e-06 28.3 0.0 3.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 EAU89303.2 - 9.5e-05 22.2 0.0 0.0017 18.2 0.0 2.5 3 0 0 3 3 3 1 FAD-binding domain DUF4293 PF14126.1 EAU89303.2 - 0.036 13.9 1.9 0.055 13.3 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF719 PF05334.8 EAU89303.2 - 0.043 13.8 0.2 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) RVP PF00077.15 EAU89305.2 - 0.0076 16.1 0.1 0.085 12.7 0.0 2.2 1 1 1 2 2 2 1 Retroviral aspartyl protease Mad3_BUB1_I PF08311.7 EAU89306.1 - 2.3e-26 92.0 0.0 3.5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Sec23_trunk PF04811.10 EAU89307.2 - 4.1e-73 245.7 0.0 7.5e-73 244.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EAU89307.2 - 1.4e-21 75.8 0.1 4.1e-21 74.3 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EAU89307.2 - 6.5e-17 60.8 8.1 1.3e-16 59.8 5.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EAU89307.2 - 8.7e-14 51.8 0.1 2.4e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EAU89307.2 - 6.7e-07 28.9 0.0 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 EAU89307.2 - 9.4e-05 22.1 3.0 9.4e-05 22.1 2.1 2.5 2 0 0 2 2 2 1 WW domain ATP-synt_10 PF05176.9 EAU89309.1 - 2.4e-67 226.8 0.0 3.2e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Histone PF00125.19 EAU89310.1 - 1.5e-26 92.3 0.0 1.9e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAU89310.1 - 1.5e-06 28.1 0.0 2.1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF563 PF04577.9 EAU89311.2 - 3.4e-05 23.8 0.1 7.4e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) MFS_1 PF07690.11 EAU89312.1 - 3.1e-39 134.6 50.8 4.6e-39 134.1 35.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EAU89312.1 - 0.0023 16.1 7.7 0.004 15.3 5.3 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector Sugar_tr PF00083.19 EAU89312.1 - 0.006 15.2 37.1 0.02 13.4 25.8 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4066 PF13278.1 EAU89313.1 - 2.3e-19 69.2 0.0 3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EAU89313.1 - 6.6e-06 25.6 0.0 9.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family RRM_1 PF00076.17 EAU89315.2 - 1.6e-33 114.1 0.0 1.2e-12 47.2 0.0 4.5 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89315.2 - 4.7e-20 71.3 0.0 1.4e-08 34.6 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU89315.2 - 2.3e-14 52.9 0.0 9.5e-07 28.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EAU89315.2 - 0.00011 21.7 1.3 0.016 14.8 0.1 3.1 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain PAM2 PF07145.10 EAU89315.2 - 0.036 13.5 2.5 0.11 12.0 1.7 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Limkain-b1 PF11608.3 EAU89315.2 - 0.094 12.4 0.1 24 4.7 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 RRM_1 PF00076.17 EAU89316.2 - 1.8e-12 46.6 0.0 2.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89316.2 - 1.4e-10 40.9 0.0 2.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EAU89316.2 - 4.3e-09 36.7 0.4 4.3e-09 36.7 0.3 2.1 2 0 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EAU89316.2 - 2e-08 33.9 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EAU89316.2 - 0.068 13.2 2.4 0.084 12.9 0.1 2.0 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding WD40 PF00400.27 EAU89317.2 - 9.4e-47 155.2 20.6 5.8e-07 29.1 0.4 11.1 11 0 0 11 11 11 7 WD domain, G-beta repeat PD40 PF07676.7 EAU89317.2 - 0.007 16.0 0.5 2.7 7.7 0.1 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EAU89317.2 - 0.024 12.9 0.2 2.5 6.3 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EAU89317.2 - 5.8 6.3 5.3 16 4.9 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Pheromone PF08015.6 EAU89320.1 - 2.4e-10 41.1 1.4 4.3e-10 40.2 1.0 1.4 1 1 0 1 1 1 1 Fungal mating-type pheromone SPC25 PF06703.6 EAU89321.2 - 3.7e-31 107.9 0.2 2.8e-29 101.8 0.1 2.2 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Terpene_synth_C PF03936.11 EAU89322.2 - 2.8e-16 59.5 0.0 4.4e-16 58.9 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 EAU89323.2 - 3.3e-21 75.4 26.9 9.4e-18 64.0 4.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EAU89323.2 - 0.16 11.7 4.5 0.16 11.7 0.1 3.0 4 0 0 4 4 4 0 MFS_1 like family DUF4102 PF13356.1 EAU89324.2 - 0.036 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) DEAD PF00270.24 EAU89326.2 - 5.7e-42 143.0 0.1 2.3e-41 141.1 0.1 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU89326.2 - 3.9e-26 90.7 0.0 1e-24 86.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU89326.2 - 0.0019 18.0 0.4 0.0063 16.3 0.0 2.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Gram_pos_anchor PF00746.16 EAU89328.2 - 0.091 12.5 0.2 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Gram positive anchor DrsE_2 PF13686.1 EAU89329.2 - 0.017 14.8 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family WD40 PF00400.27 EAU89331.2 - 2.4e-59 195.2 22.5 1.8e-12 46.6 0.0 12.9 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 EAU89331.2 - 2.4e-21 75.7 0.0 4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Gmad1 PF10647.4 EAU89331.2 - 6e-06 25.8 0.0 0.001 18.5 0.0 3.3 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EAU89331.2 - 0.00027 20.4 0.4 0.032 13.6 0.1 3.6 3 1 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 EAU89331.2 - 0.017 14.7 5.9 8.7 6.1 0.0 5.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.1 EAU89331.2 - 0.038 12.9 0.0 0.32 9.9 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.7 EAU89331.2 - 0.048 11.4 0.0 2.3 5.9 0.0 2.9 3 1 0 4 4 4 0 IKI3 family PQQ PF01011.16 EAU89331.2 - 0.055 13.0 0.2 26 4.5 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat TFIIIC_delta PF12657.2 EAU89331.2 - 0.057 13.1 0.0 12 5.6 0.0 3.4 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term TPR_14 PF13428.1 EAU89336.1 - 1.6e-26 90.3 30.1 0.0006 20.2 0.1 12.5 5 3 9 14 14 13 7 Tetratricopeptide repeat HAT PF02184.11 EAU89336.1 - 1.8e-24 85.1 53.0 7.3e-09 35.2 2.1 13.3 14 1 0 14 14 14 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EAU89336.1 - 2e-18 66.4 6.3 0.0037 17.5 0.0 7.5 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAU89336.1 - 1.3e-14 54.3 24.9 0.00055 20.5 0.0 7.9 5 3 6 11 11 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EAU89336.1 - 6.2e-14 50.7 13.2 0.059 13.3 0.0 9.1 11 0 0 11 11 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAU89336.1 - 8.9e-11 41.2 8.4 0.15 11.7 0.0 6.6 6 1 1 7 7 7 4 TPR repeat Suf PF05843.9 EAU89336.1 - 2.6e-09 37.2 23.9 0.00044 20.0 0.2 7.2 3 3 3 6 6 6 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EAU89336.1 - 8.9e-08 31.7 2.6 0.002 18.2 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU89336.1 - 2e-07 30.3 0.5 5 6.8 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU89336.1 - 2.1e-07 30.7 14.9 0.016 15.0 0.0 7.1 5 3 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EAU89336.1 - 3.9e-07 29.4 26.5 0.079 12.0 8.3 5.9 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAU89336.1 - 9.2e-06 25.0 17.9 4.1 7.4 0.0 8.8 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU89336.1 - 1.3e-05 24.6 2.5 9.3 6.3 0.0 6.6 7 1 1 8 8 6 0 Tetratricopeptide repeat SNAP PF14938.1 EAU89336.1 - 4.9e-05 22.6 8.2 0.0012 18.1 0.9 4.0 3 2 1 4 4 4 1 Soluble NSF attachment protein, SNAP Mad3_BUB1_I PF08311.7 EAU89336.1 - 0.00041 20.1 16.5 1.3 8.8 0.4 6.8 4 2 2 6 6 6 3 Mad3/BUB1 homology region 1 TPR_6 PF13174.1 EAU89336.1 - 0.00061 20.0 13.7 11 6.7 0.0 8.5 9 0 0 9 9 8 0 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EAU89336.1 - 0.011 15.4 0.6 0.011 15.4 0.4 5.8 5 2 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_3 PF07720.7 EAU89336.1 - 0.17 11.6 3.7 53 3.7 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EAU89336.1 - 0.23 11.5 4.0 2.6 8.2 0.1 4.0 3 1 1 4 4 4 0 c-SKI Smad4 binding domain TPR_4 PF07721.9 EAU89336.1 - 1.6 9.3 8.1 1.2e+02 3.5 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat Cnd3 PF12719.2 EAU89337.2 - 5.7e-42 143.7 4.5 5e-37 127.4 0.3 2.9 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EAU89337.2 - 0.00012 21.9 4.5 7.9 6.8 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EAU89337.2 - 0.00012 22.2 8.2 0.0093 16.2 0.4 4.6 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EAU89337.2 - 2.7 8.6 7.2 39 4.9 1.3 4.8 3 1 1 4 4 4 0 HEAT-like repeat Cnd3 PF12719.2 EAU89338.2 - 2.5e-31 108.7 11.6 4.3e-26 91.5 0.4 4.9 4 1 1 5 5 5 3 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EAU89338.2 - 1.1e-05 25.5 3.5 3e-05 24.2 0.1 3.3 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 EAU89338.2 - 0.0045 16.9 1.1 7.9 6.8 0.2 5.0 4 0 0 4 4 4 1 HEAT repeat STAT1_TAZ2bind PF12162.3 EAU89338.2 - 0.012 14.9 1.4 0.19 11.1 0.3 2.9 3 0 0 3 3 3 0 STAT1 TAZ2 binding domain Phage_antiter_Q PF06323.6 EAU89339.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q Rab5-bind PF09311.6 EAU89339.1 - 0.054 13.3 0.7 0.16 11.8 0.2 1.7 2 0 0 2 2 2 0 Rabaptin-like protein F-box-like PF12937.2 EAU89340.1 - 2.9e-07 30.0 0.0 1.7e-06 27.6 0.0 2.4 2 1 0 2 2 2 1 F-box-like Myosin_tail_1 PF01576.14 EAU89340.1 - 0.2 9.3 0.1 0.27 8.9 0.0 1.1 1 0 0 1 1 1 0 Myosin tail F-box PF00646.28 EAU89340.1 - 0.34 10.6 6.6 0.33 10.6 0.2 3.4 3 0 0 3 3 3 0 F-box domain Pkinase PF00069.20 EAU89342.2 - 6.5e-50 169.6 0.0 9.9e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89342.2 - 4e-24 85.0 0.0 5.5e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EAU89342.2 - 0.00099 18.0 0.2 0.0018 17.1 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EAU89342.2 - 0.0045 15.9 0.0 0.0076 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU89342.2 - 0.012 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3827 PF12877.2 EAU89343.1 - 0.28 9.2 10.6 0.38 8.8 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Golgin_A5 PF09787.4 EAU89343.1 - 1.3 7.4 10.2 1.7 7.0 7.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 BLVR PF06375.6 EAU89344.2 - 0.016 15.0 1.6 0.27 11.0 0.3 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) BRF1 PF07741.8 EAU89344.2 - 1.6 8.9 13.9 2.8 8.2 4.5 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1387 PF07139.6 EAU89344.2 - 3.1 7.3 7.8 2.6 7.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Cucumo_2B PF03263.8 EAU89344.2 - 4.3 7.6 8.5 1.4 9.2 2.0 2.4 2 0 0 2 2 2 0 Cucumovirus protein 2B Ribosomal_S5_C PF03719.10 EAU89345.2 - 1.7e-16 59.2 0.0 4.7e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EAU89345.2 - 8.6e-08 31.8 0.6 1.8e-07 30.8 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain PHB_depo_C PF06850.6 EAU89345.2 - 0.035 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus PITH PF06201.8 EAU89346.2 - 6.8e-39 133.0 0.0 8.4e-39 132.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain C2 PF00168.25 EAU89347.2 - 3.6e-17 61.9 0.1 7.8e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain COesterase PF00135.23 EAU89349.2 - 7.3e-55 186.6 0.0 6.7e-30 104.2 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family COesterase PF00135.23 EAU89350.1 - 1.7e-101 340.5 0.0 2.2e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU89350.1 - 5.3e-11 42.4 0.0 1.5e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU89350.1 - 0.0026 17.0 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_transf_90 PF05686.7 EAU89351.1 - 4.9e-20 71.5 0.1 9.7e-20 70.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 90 YfzA PF14118.1 EAU89351.1 - 0.013 15.5 0.2 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 YfzA-like protein COesterase PF00135.23 EAU89353.1 - 2.3e-101 340.1 0.0 2.9e-101 339.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU89353.1 - 2.4e-09 37.0 0.2 7.6e-09 35.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU89353.1 - 0.019 14.2 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family CAP59_mtransfer PF11735.3 EAU89357.1 - 1.6e-80 269.8 0.0 2.1e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.17 EAU89364.2 - 6.7e-36 123.8 0.0 1.2e-35 122.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Neugrin PF06413.6 EAU89365.1 - 1.3e-12 48.0 1.7 1.9e-12 47.5 1.2 1.2 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EAU89365.1 - 1.6e-07 31.4 6.5 2.3e-07 30.9 4.5 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.7 EAU89365.1 - 0.008 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 HTH domain Rrf2 PF02082.15 EAU89365.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Sigma70_r4 PF04545.11 EAU89365.1 - 0.029 13.6 0.1 0.25 10.7 0.1 2.5 1 1 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EAU89365.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF429 PF04250.8 EAU89365.1 - 0.14 11.3 0.5 0.18 11.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Sigma70_r3 PF04539.11 EAU89365.1 - 0.16 11.9 0.9 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 region 3 Cofilin_ADF PF00241.15 EAU89366.2 - 2e-16 59.9 0.0 2.3e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Acetyltransf_1 PF00583.19 EAU89367.1 - 1.8e-15 56.6 0.0 2.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU89367.1 - 8e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAU89367.1 - 6.6e-05 23.0 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAU89367.1 - 0.00027 21.1 0.0 0.00036 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU89367.1 - 0.00094 19.1 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAU89367.1 - 0.0017 18.0 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EAU89367.1 - 0.024 14.4 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain NAC PF01849.13 EAU89368.1 - 9.7e-22 76.2 0.1 1.5e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 NAC domain PIG-S PF10510.4 EAU89369.2 - 2.8e-93 313.3 7.8 2e-56 191.7 0.0 3.1 1 1 1 3 3 3 3 Phosphatidylinositol-glycan biosynthesis class S protein Myb_DNA-binding PF00249.26 EAU89370.2 - 1.3e-06 28.3 0.0 2.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAU89370.2 - 0.0003 20.8 0.1 0.00096 19.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Glyco_hydro_47 PF01532.15 EAU89371.2 - 3.1e-117 391.9 0.0 3.6e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Transferase PF02458.10 EAU89372.2 - 0.18 10.2 0.0 3.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Transferase family F-box-like PF12937.2 EAU89373.1 - 4.5e-07 29.4 0.2 1.8e-06 27.5 0.2 2.1 1 0 0 1 1 1 1 F-box-like LRR_5 PF13306.1 EAU89373.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) Glyco_hydro_16 PF00722.16 EAU89376.2 - 0.00075 18.8 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UQ_con PF00179.21 EAU89378.2 - 2.3e-52 176.1 0.0 2.6e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAU89378.2 - 0.00011 21.9 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EAU89378.2 - 0.0014 18.4 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EAU89378.2 - 0.019 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain BNIP3 PF06553.7 EAU89379.2 - 9.6 5.5 20.1 2.1 7.6 7.0 3.2 1 1 2 3 3 3 0 BNIP3 PIG-L PF02585.12 EAU89380.2 - 5e-19 69.0 0.1 1e-10 42.1 0.0 2.2 2 0 0 2 2 2 2 GlcNAc-PI de-N-acetylase DUF1770 PF08589.5 EAU89382.1 - 0.00029 21.3 0.3 0.00061 20.3 0.2 1.6 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) p450 PF00067.17 EAU89384.1 - 2.8e-76 256.9 0.0 1.3e-75 254.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.1 EAU89385.2 - 8.7e-23 80.1 0.0 2.1e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU89385.2 - 4.8e-14 52.0 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU89385.2 - 1.2e-08 34.8 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU89385.2 - 3.3e-05 24.3 0.0 7e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EAU89385.2 - 4.2e-05 23.6 0.0 0.0008 19.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain F-box-like PF12937.2 EAU89386.1 - 8.3e-07 28.6 2.3 2.7e-06 26.9 1.6 2.0 1 0 0 1 1 1 1 F-box-like OPT PF03169.10 EAU89388.1 - 8.8e-95 318.4 32.4 1.1e-94 318.0 22.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ubiquitin PF00240.18 EAU89389.1 - 2.8e-14 52.2 0.0 5.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1735 PF08522.5 EAU89389.1 - 0.00078 19.7 0.1 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1735) Rad60-SLD PF11976.3 EAU89389.1 - 0.00079 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ndufs5 PF10200.4 EAU89390.1 - 3.5e-05 23.6 0.3 4.4e-05 23.3 0.2 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 EAU89390.1 - 0.00073 19.2 0.9 0.0011 18.6 0.7 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.3 EAU89390.1 - 0.076 13.1 0.4 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) CHCH PF06747.8 EAU89390.1 - 0.1 12.5 1.4 0.22 11.4 1.0 1.6 1 1 0 1 1 1 0 CHCH domain HMG_box PF00505.14 EAU89391.2 - 5.2e-11 42.6 5.4 1.2e-10 41.5 3.7 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU89391.2 - 0.00074 19.8 0.9 0.0018 18.6 0.6 1.6 1 0 0 1 1 1 1 HMG-box domain Nucleo_P87 PF07267.6 EAU89391.2 - 1.4 7.4 7.2 1.9 7.0 5.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box-like PF12937.2 EAU89393.2 - 0.015 15.0 0.1 0.057 13.1 0.1 2.1 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EAU89393.2 - 0.017 14.7 2.1 0.021 14.4 0.1 2.2 2 0 0 2 2 2 0 F-box domain Pkinase PF00069.20 EAU89394.1 - 4.2e-68 229.2 0.0 5.1e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89394.1 - 2.2e-27 95.7 0.0 3.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU89394.1 - 1.4e-06 27.5 0.0 2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EAU89394.1 - 0.00068 19.0 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EAU89394.1 - 0.0032 16.5 0.3 0.0084 15.2 0.2 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU89394.1 - 0.0055 16.4 0.3 0.19 11.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family SporV_AA PF12164.3 EAU89394.1 - 0.057 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Stage V sporulation protein AA TcdB_toxin_midN PF12256.3 EAU89394.1 - 0.081 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region YukC PF10140.4 EAU89394.1 - 0.097 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC NTF2 PF02136.15 EAU89395.1 - 1e-26 93.6 0.1 1.6e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EAU89395.1 - 2.2e-10 40.0 0.0 3.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU89395.1 - 1.9e-06 27.5 0.0 3.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89395.1 - 5.6e-06 26.2 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU89395.1 - 0.00012 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Het-C PF07217.6 EAU89396.1 - 1.1e-219 730.7 0.0 1.3e-219 730.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PsbH PF00737.15 EAU89397.2 - 0.11 12.1 1.4 0.19 11.3 0.2 2.0 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Glyco_hydro_61 PF03443.9 EAU89398.2 - 1.6e-49 168.6 0.0 2e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_48 PF02922.13 EAU89398.2 - 0.087 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Pkinase PF00069.20 EAU89399.2 - 3e-52 177.3 0.0 4e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89399.2 - 2.4e-28 98.9 0.0 3.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU89399.2 - 2.3e-07 30.0 0.0 3.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EAU89399.2 - 0.0046 15.7 0.3 0.0092 14.8 0.2 1.4 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EAU89399.2 - 0.0078 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU89399.2 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAT1 PF09770.4 EAU89399.2 - 3 5.9 5.5 4.1 5.5 3.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gln-synt_C PF00120.19 EAU89400.1 - 1.3e-55 188.4 0.0 1.7e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_C PF00120.19 EAU89401.2 - 6.2e-53 179.5 0.0 7.9e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DASH_Dam1 PF08653.5 EAU89402.1 - 6.9e-13 48.1 0.6 1.3e-12 47.2 0.4 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF572 PF04502.8 EAU89402.1 - 0.044 13.0 5.0 0.059 12.5 3.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dicty_REP PF05086.7 EAU89402.1 - 0.19 9.4 1.7 0.24 9.1 1.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4230 PF14014.1 EAU89402.1 - 6.3 6.6 10.0 10 5.9 6.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) CBM_1 PF00734.13 EAU89405.1 - 1.6e-07 30.8 1.1 1.6e-07 30.8 0.8 3.5 3 1 0 3 3 3 1 Fungal cellulose binding domain BTB PF00651.26 EAU89406.1 - 0.00086 19.2 0.3 0.018 14.9 0.1 2.8 1 1 1 2 2 2 1 BTB/POZ domain DUF2684 PF10885.3 EAU89406.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) NDUF_B7 PF05676.8 EAU89407.1 - 7.8e-29 98.8 2.0 9.1e-29 98.6 1.4 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EAU89407.1 - 0.1 12.3 2.3 0.15 11.8 1.6 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Glyco_hydro_61 PF03443.9 EAU89408.2 - 1.9e-51 174.9 0.0 2.2e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MAPEG PF01124.13 EAU89409.2 - 8.6e-14 51.2 0.7 9.4e-14 51.1 0.5 1.1 1 0 0 1 1 1 1 MAPEG family Glyoxal_oxid_N PF07250.6 EAU89410.1 - 1.6e-38 132.2 0.0 7.4e-36 123.4 0.0 3.5 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EAU89410.1 - 6.8e-20 70.9 0.2 1.6e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EAU89410.1 - 1.9e-05 24.3 8.5 0.017 14.8 0.1 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain B_lectin PF01453.19 EAU89410.1 - 0.074 12.9 0.1 1.4 8.8 0.0 3.0 4 0 0 4 4 4 0 D-mannose binding lectin Histone PF00125.19 EAU89413.1 - 3.5e-22 78.2 0.2 5.1e-22 77.7 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAU89413.1 - 2.5e-06 27.4 0.1 5.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EAU89413.1 - 0.00023 21.3 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EAU89413.1 - 0.0095 14.6 1.1 0.012 14.3 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF1018 PF06252.7 EAU89413.1 - 0.048 14.1 0.3 0.064 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 EAU89413.1 - 0.064 12.6 0.1 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone PF00125.19 EAU89414.1 - 1.8e-26 92.0 0.0 2.3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAU89414.1 - 2.1e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MFS_1 PF07690.11 EAU89415.2 - 8.6e-14 51.0 46.4 5.4e-12 45.0 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EAU89415.2 - 0.34 10.9 9.6 0.085 12.8 0.8 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1228) PH_9 PF15410.1 EAU89416.2 - 5.2e-06 26.6 0.0 0.0087 16.2 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.24 EAU89416.2 - 0.092 12.9 0.0 6.1 7.1 0.0 2.3 2 0 0 2 2 2 0 PH domain Metallophos PF00149.23 EAU89417.1 - 2.8e-44 150.9 0.1 3.5e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 EAU89418.1 - 5.3e-87 292.2 25.8 6.1e-87 292.0 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU89418.1 - 6.9e-26 90.7 28.2 1.3e-21 76.6 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAU89418.1 - 6.8e-06 24.7 3.8 6.8e-06 24.7 2.6 3.3 2 2 2 4 4 4 2 MFS/sugar transport protein ATG11 PF10377.4 EAU89419.2 - 1.3e-33 115.6 0.1 5.1e-33 113.7 0.1 2.1 1 0 0 1 1 1 1 Autophagy-related protein 11 DUF2316 PF10078.4 EAU89419.2 - 4.6 7.2 7.0 1.4 8.9 0.3 3.3 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) F-box-like PF12937.2 EAU89421.2 - 0.078 12.7 0.2 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like Polysacc_lyase PF14099.1 EAU89422.2 - 4.2e-05 23.3 0.0 0.00036 20.2 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide lyase Mcp5_PH PF12814.2 EAU89423.1 - 2.7e-43 146.7 0.3 1.1e-42 144.7 0.0 2.2 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology Myosin_tail_1 PF01576.14 EAU89423.1 - 1.4e-05 23.0 22.2 1.4e-05 23.0 15.4 2.4 3 0 0 3 3 3 2 Myosin tail ERM PF00769.14 EAU89423.1 - 0.0025 17.3 16.3 0.0025 17.3 11.3 3.0 3 0 0 3 3 3 1 Ezrin/radixin/moesin family IMCp PF12314.3 EAU89423.1 - 0.0028 17.7 29.0 0.0028 17.7 20.1 4.2 2 1 1 3 3 2 2 Inner membrane complex protein Filament PF00038.16 EAU89423.1 - 0.0045 16.5 18.6 0.0045 16.5 12.9 2.4 3 0 0 3 3 3 1 Intermediate filament protein PH PF00169.24 EAU89423.1 - 0.029 14.5 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 PH domain Reo_sigmaC PF04582.7 EAU89423.1 - 0.081 12.0 7.5 0.19 10.8 2.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EAU89423.1 - 0.18 10.2 15.3 0.012 14.1 7.0 1.6 2 0 0 2 2 2 0 AAA domain ADIP PF11559.3 EAU89423.1 - 0.68 9.8 42.9 0.11 12.3 9.6 4.2 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding RCC1 PF00415.13 EAU89423.1 - 0.98 9.6 4.8 0.19 11.9 0.2 2.3 2 0 0 2 2 1 0 Regulator of chromosome condensation (RCC1) repeat V_ATPase_I PF01496.14 EAU89423.1 - 1.3 6.7 10.3 3.3 5.4 7.1 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 EAU89423.1 - 2.9 7.7 27.9 7.3 6.4 7.6 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.6 EAU89423.1 - 7.5 5.9 29.5 0.89 8.9 4.8 3.4 2 1 1 3 3 3 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EAU89423.1 - 7.8 6.3 34.6 5 7.0 6.3 4.6 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Sec23_trunk PF04811.10 EAU89424.2 - 2.4e-48 164.6 0.0 3.6e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 EAU89424.2 - 1.4e-18 67.1 0.2 4e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAU89424.2 - 2.9e-15 55.5 3.9 6.3e-15 54.4 2.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EAU89424.2 - 1e-07 31.5 0.0 2.2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Sec23_helical PF04815.10 EAU89424.2 - 3.6e-07 29.5 0.1 7.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Zn_Tnp_IS1595 PF12760.2 EAU89424.2 - 9.7 6.0 8.4 4.4 7.2 3.8 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain F-box-like PF12937.2 EAU89425.2 - 0.00043 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like PDEase_I PF00233.14 EAU89427.2 - 9.8e-39 133.4 0.6 1.2e-35 123.3 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EAU89427.2 - 0.08 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 HD domain MutS_V PF00488.16 EAU89431.2 - 2.2e-76 256.3 0.0 3.9e-76 255.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAU89431.2 - 1.9e-47 161.7 0.4 4.3e-47 160.5 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EAU89431.2 - 1.4e-34 118.5 0.1 4.8e-34 116.7 0.1 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EAU89431.2 - 1.6e-10 41.1 0.1 8.2e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EAU89431.2 - 0.017 15.3 0.1 0.065 13.4 0.1 2.1 1 1 0 1 1 1 0 MutS family domain IV 3HCDH_N PF02737.13 EAU89431.2 - 0.025 14.2 0.9 2.4 7.8 0.1 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_29 PF13555.1 EAU89431.2 - 0.03 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU89431.2 - 0.078 13.2 5.6 0.11 12.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF4139 PF13598.1 EAU89433.2 - 9e-71 238.7 0.0 1.5e-70 237.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EAU89433.2 - 2.1e-18 66.6 5.3 8.3e-16 58.3 0.0 2.6 1 1 1 2 2 2 2 N-terminal domain of unknown function (DUF4140) ERM PF00769.14 EAU89433.2 - 0.0029 17.1 1.3 0.0041 16.6 0.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YlqD PF11068.3 EAU89433.2 - 0.01 15.9 1.0 0.021 14.8 0.7 1.5 1 0 0 1 1 1 1 YlqD protein DUF2051 PF09738.4 EAU89433.2 - 0.015 14.5 0.4 0.023 13.9 0.3 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) APG6 PF04111.7 EAU89433.2 - 0.018 14.1 2.5 0.026 13.5 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EAU89433.2 - 0.035 12.5 0.2 0.051 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 EAU89433.2 - 0.052 12.2 1.6 0.081 11.5 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EAU89433.2 - 0.057 11.2 0.4 0.076 10.8 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_I PF06008.9 EAU89433.2 - 0.088 12.1 3.3 0.13 11.5 2.3 1.1 1 0 0 1 1 1 0 Laminin Domain I Spectrin PF00435.16 EAU89433.2 - 0.11 12.7 1.8 0.2 11.9 1.2 1.4 1 0 0 1 1 1 0 Spectrin repeat DASH_Spc19 PF08287.6 EAU89433.2 - 0.14 11.7 3.9 0.53 9.8 2.4 1.9 1 1 1 2 2 2 0 Spc19 MASE1 PF05231.9 EAU89435.2 - 1.1 8.1 22.8 0.23 10.4 0.2 2.6 1 1 1 2 2 2 0 MASE1 Lig_chan PF00060.21 EAU89435.2 - 8.6 6.0 7.4 11 5.7 2.5 2.6 2 1 0 2 2 2 0 Ligand-gated ion channel DFP PF04127.10 EAU89436.1 - 7.6e-21 74.5 0.0 3.3e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein AA_kinase PF00696.23 EAU89436.1 - 0.11 12.0 0.0 2.2 7.7 0.0 2.5 3 0 0 3 3 3 0 Amino acid kinase family PAS_9 PF13426.1 EAU89436.1 - 0.14 12.5 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 PAS domain Sec2p PF06428.6 EAU89437.1 - 4.3e-13 48.9 13.7 4.3e-13 48.9 9.5 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF812 PF05667.6 EAU89437.1 - 2.3 6.5 19.4 14 4.0 13.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Transferase PF02458.10 EAU89438.2 - 0.024 13.1 0.0 0.52 8.6 0.0 2.2 2 0 0 2 2 2 0 Transferase family Condensation PF00668.15 EAU89438.2 - 0.044 12.6 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Condensation domain ABC_tran PF00005.22 EAU89439.2 - 1.7e-32 112.5 0.1 6.7e-18 65.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 EAU89439.2 - 6.2e-14 51.2 4.9 1.5e-13 50.0 3.4 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EAU89439.2 - 8.3e-13 48.9 8.0 0.00032 20.7 0.1 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EAU89439.2 - 3e-10 39.6 4.3 0.0052 16.0 0.1 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EAU89439.2 - 5.7e-07 28.8 3.2 5.7e-07 28.8 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_22 PF13401.1 EAU89439.2 - 5.2e-06 26.6 0.0 0.0065 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EAU89439.2 - 2e-05 24.8 0.0 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU89439.2 - 3.2e-05 24.7 0.3 0.13 13.0 0.1 2.9 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAU89439.2 - 3.7e-05 22.9 1.0 0.23 10.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EAU89439.2 - 8.2e-05 21.8 5.7 1.2 8.1 0.4 4.6 4 1 1 5 5 5 1 AAA ATPase domain NACHT PF05729.7 EAU89439.2 - 0.00012 21.8 0.8 0.049 13.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 EAU89439.2 - 0.00013 21.4 0.4 0.2 11.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EAU89439.2 - 0.00015 22.2 1.6 0.07 13.6 0.0 3.4 3 1 0 3 3 2 1 Miro-like protein AAA_33 PF13671.1 EAU89439.2 - 0.0003 20.6 0.0 0.11 12.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 EAU89439.2 - 0.00068 19.3 2.3 0.00068 19.3 1.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.1 EAU89439.2 - 0.00079 19.7 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU89439.2 - 0.0011 18.9 0.5 0.39 10.6 0.0 2.5 2 2 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EAU89439.2 - 0.0012 18.7 0.1 1.1 9.2 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit VirE PF05272.6 EAU89439.2 - 0.0013 18.2 0.0 0.69 9.3 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E RNA_helicase PF00910.17 EAU89439.2 - 0.0016 18.5 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Fer4_2 PF12797.2 EAU89439.2 - 0.0016 18.2 1.8 0.0016 18.2 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.1 EAU89439.2 - 0.0021 17.8 11.4 0.0044 16.8 7.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EAU89439.2 - 0.0026 18.1 2.1 0.0026 18.1 1.4 2.3 1 1 2 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EAU89439.2 - 0.0027 17.4 1.0 0.0027 17.4 0.7 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain UPF0079 PF02367.12 EAU89439.2 - 0.0034 17.0 0.3 0.09 12.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EAU89439.2 - 0.0034 16.8 1.7 0.71 9.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EAU89439.2 - 0.006 16.0 0.1 2.9 7.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EAU89439.2 - 0.011 15.4 1.6 3 7.5 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Fer4_16 PF13484.1 EAU89439.2 - 0.013 16.2 0.2 0.013 16.2 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NB-ARC PF00931.17 EAU89439.2 - 0.013 14.4 0.0 0.4 9.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_3 PF12798.2 EAU89439.2 - 0.015 15.7 4.3 0.015 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_28 PF13521.1 EAU89439.2 - 0.016 15.1 0.1 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EAU89439.2 - 0.017 14.8 0.8 0.61 9.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EAU89439.2 - 0.019 14.8 1.1 7.6 6.4 0.0 3.2 2 2 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 EAU89439.2 - 0.025 14.8 12.3 0.096 12.9 8.5 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain PUL PF08324.6 EAU89439.2 - 0.038 12.7 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 PUL domain Rad17 PF03215.10 EAU89439.2 - 0.053 12.1 0.0 0.33 9.5 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EAU89439.2 - 0.062 12.8 1.1 0.69 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EAU89439.2 - 0.067 12.5 0.0 3.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase Fer4_8 PF13183.1 EAU89439.2 - 0.1 12.6 8.8 0.091 12.8 0.8 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_23 PF13476.1 EAU89439.2 - 0.24 11.7 8.2 0.3 11.3 0.2 2.6 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAU89439.2 - 0.29 10.7 0.3 9.6 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 EAU89439.2 - 0.47 10.9 13.4 0.084 13.2 1.6 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_13 PF13166.1 EAU89439.2 - 0.58 8.5 0.0 0.58 8.5 0.0 2.4 4 0 0 4 4 4 0 AAA domain Fer4_15 PF13459.1 EAU89439.2 - 3 8.4 8.5 0.22 12.0 0.9 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_17 PF13534.1 EAU89439.2 - 9.7 6.6 11.9 0.16 12.3 0.9 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Rotamase_3 PF13616.1 EAU89440.2 - 1.2e-19 70.6 0.3 1.8e-19 70.0 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EAU89440.2 - 1.7e-19 70.3 0.0 2.9e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EAU89440.2 - 7.4e-07 29.8 0.1 1.3e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Fcf1 PF04900.7 EAU89441.1 - 0.082 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Fcf1 Ribophorin_II PF05817.9 EAU89445.1 - 1e-26 93.3 0.0 1.3e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II COesterase PF00135.23 EAU89446.2 - 1.9e-97 327.2 0.2 1.4e-95 321.0 0.1 2.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU89446.2 - 6.2e-08 32.4 0.1 6.8e-07 29.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EAU89446.2 - 0.0012 18.0 0.2 0.0023 17.1 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Spond_N PF06468.8 EAU89446.2 - 0.076 12.6 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Spondin_N NDUFA12 PF05071.11 EAU89447.2 - 5.9e-11 42.7 0.2 5.9e-11 42.7 0.1 1.9 2 1 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 UPF0449 PF15136.1 EAU89447.2 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 MscS_TM PF12794.2 EAU89448.2 - 0.023 13.2 5.4 0.037 12.6 3.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF202 PF02656.10 EAU89448.2 - 1.9 8.7 6.9 1e+02 3.2 4.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF202) eIF3_subunit PF08597.5 EAU89450.2 - 1 8.8 8.6 1.1 8.7 6.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit XPG_I PF00867.13 EAU89453.2 - 1.1e-15 57.4 0.0 2.2e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAU89453.2 - 0.0054 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EAU89453.2 - 0.032 14.4 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Coatomer_WDAD PF04053.9 EAU89454.2 - 3.6e-142 474.2 0.0 7.2e-142 473.2 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EAU89454.2 - 2.5e-95 319.5 0.0 3.5e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EAU89454.2 - 2.4e-59 195.2 9.8 9.1e-11 41.2 0.0 8.2 9 0 0 9 9 9 6 WD domain, G-beta repeat Nup160 PF11715.3 EAU89454.2 - 0.0046 15.1 2.7 0.6 8.1 0.0 3.5 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EAU89454.2 - 0.041 13.4 0.4 0.23 11.0 0.2 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS Ferritin-like PF12902.2 EAU89454.2 - 0.049 13.2 0.2 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Ferritin-like CAP59_mtransfer PF11735.3 EAU89457.2 - 3.3e-66 222.9 0.0 4.3e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Peptidase_M43 PF05572.8 EAU89462.2 - 1.3e-09 37.7 0.0 2.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EAU89462.2 - 2.5e-05 24.7 0.1 3.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU89462.2 - 5.9e-05 23.2 0.0 9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU89462.2 - 8.8e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M66 PF10462.4 EAU89462.2 - 0.039 12.8 0.4 0.059 12.2 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 EAU89462.2 - 0.051 13.1 0.1 0.08 12.4 0.0 1.4 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like 2-oxoacid_dh PF00198.18 EAU89463.2 - 2.5e-83 278.8 0.1 3.4e-83 278.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EAU89463.2 - 5.1e-20 70.8 2.3 9.9e-20 69.9 1.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EAU89463.2 - 0.00015 21.3 0.5 0.001 18.7 0.2 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_2 PF12700.2 EAU89463.2 - 0.00019 20.6 1.9 0.055 12.6 0.4 2.4 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EAU89463.2 - 0.00046 20.4 0.3 0.34 11.2 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 EAU89463.2 - 0.0019 17.8 0.5 0.0049 16.5 0.3 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein ABC_tran PF00005.22 EAU89464.2 - 2.1e-51 173.7 0.0 5.1e-31 107.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAU89464.2 - 2.6e-31 109.0 25.3 3.3e-25 89.0 5.8 4.0 4 1 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EAU89464.2 - 6.2e-09 35.4 0.0 0.015 14.5 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU89464.2 - 1.3e-06 28.6 0.7 0.033 14.1 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EAU89464.2 - 7.1e-06 25.5 0.2 0.086 12.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EAU89464.2 - 0.00021 20.2 0.0 0.045 12.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EAU89464.2 - 0.00032 20.1 1.0 0.061 12.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EAU89464.2 - 0.00074 19.0 0.1 2.4 7.4 0.1 3.5 4 0 0 4 4 4 2 AAA-like domain AAA_23 PF13476.1 EAU89464.2 - 0.005 17.1 0.8 2.7 8.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EAU89464.2 - 0.0052 16.2 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EAU89464.2 - 0.0056 16.8 0.5 8 6.6 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAU89464.2 - 0.025 14.5 0.2 4.2 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EAU89464.2 - 0.029 14.8 0.4 9.2 6.7 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 EAU89464.2 - 0.039 13.7 0.1 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_18 PF13238.1 EAU89464.2 - 0.041 14.2 0.1 6.3 7.1 0.1 3.1 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 EAU89464.2 - 0.043 12.9 0.6 7.8 5.5 0.1 2.3 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.18 EAU89464.2 - 0.21 11.5 0.4 1.8 8.5 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EAU89464.2 - 0.32 10.1 0.0 22 4.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Pox_A32 PF04665.7 EAU89464.2 - 0.55 9.4 0.6 17 4.6 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 EAU89464.2 - 0.66 9.4 4.0 1.3 8.4 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EAU89464.2 - 1.1 10.1 3.2 1.3 9.8 0.8 2.3 2 0 0 2 2 1 0 AAA domain Oxidored_FMN PF00724.15 EAU89465.1 - 2e-63 214.4 0.0 1.3e-61 208.5 0.0 2.0 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family TPR_11 PF13414.1 EAU89466.2 - 5.7e-12 45.1 10.4 0.0004 19.9 0.1 5.6 3 1 3 6 6 6 3 TPR repeat TPR_12 PF13424.1 EAU89466.2 - 9.8e-07 28.6 11.3 5.6e-05 22.9 0.5 4.7 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU89466.2 - 0.00017 22.1 8.5 0.56 10.9 0.0 5.3 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU89466.2 - 0.00025 20.7 6.9 2.2 8.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAU89466.2 - 0.00034 20.4 12.8 0.26 11.2 0.3 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU89466.2 - 0.00037 20.0 0.0 6.4 6.7 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU89466.2 - 0.00061 19.2 6.7 2.3 7.9 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU89466.2 - 0.0036 17.7 7.0 2.5 8.9 0.2 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat Rapamycin_bind PF08771.6 EAU89466.2 - 0.018 15.1 2.8 6.9 6.8 0.0 5.0 6 0 0 6 6 6 0 Rapamycin binding domain TPR_6 PF13174.1 EAU89466.2 - 0.018 15.4 1.9 7.2 7.3 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat 5_3_exonuc_N PF02739.11 EAU89466.2 - 0.096 12.0 1.1 0.92 8.8 0.1 2.3 1 1 1 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain Zn_clus PF00172.13 EAU89467.2 - 0.004 17.0 15.6 0.0061 16.4 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hemerythrin PF01814.18 EAU89470.2 - 3.7e-12 46.5 3.4 4.9e-12 46.1 2.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4419 PF14388.1 EAU89470.2 - 0.032 13.4 0.1 0.05 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) MFS_1 PF07690.11 EAU89471.2 - 3.7e-28 98.2 32.8 3.7e-28 98.2 22.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 EAU89473.2 - 8.8e-49 165.3 0.0 4.8e-30 104.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAU89473.2 - 2.8e-26 92.5 14.5 1.6e-14 54.0 2.4 3.7 3 1 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EAU89473.2 - 1.9e-09 37.0 0.7 0.003 16.7 0.1 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EAU89473.2 - 1.1e-05 24.9 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EAU89473.2 - 0.00012 22.1 0.9 0.97 9.3 0.1 3.9 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EAU89473.2 - 0.00071 19.0 0.7 0.17 11.4 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EAU89473.2 - 0.0011 19.1 0.3 3.5 7.7 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EAU89473.2 - 0.002 18.5 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EAU89473.2 - 0.0038 16.1 0.0 1.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EAU89473.2 - 0.0053 16.2 0.0 2.1 7.7 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EAU89473.2 - 0.0054 16.2 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EAU89473.2 - 0.019 14.9 0.1 1.1 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 EAU89473.2 - 0.031 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Miro PF08477.8 EAU89473.2 - 0.069 13.6 0.1 24 5.4 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_18 PF13238.1 EAU89473.2 - 0.092 13.0 0.0 17 5.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain KaiC PF06745.8 EAU89473.2 - 0.11 11.6 0.2 14 4.7 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 EAU89473.2 - 0.11 11.4 0.2 5.5 5.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EAU89473.2 - 0.8 9.1 3.0 1.6 8.1 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain BatA PF07584.6 EAU89474.1 - 0.0086 16.2 0.3 0.018 15.2 0.2 1.4 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal Herpes_gE PF02480.11 EAU89474.1 - 0.06 11.6 0.0 0.091 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IRK PF01007.15 EAU89474.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel DUF1180 PF06679.7 EAU89474.1 - 0.1 12.4 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) YajC PF02699.10 EAU89474.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit CsbD PF05532.7 EAU89476.1 - 1.5e-16 59.8 8.9 7.8e-10 38.2 0.5 2.1 1 1 1 2 2 2 2 CsbD-like Aldedh PF00171.17 EAU89477.1 - 9.2e-89 297.8 0.0 1.2e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EAU89477.1 - 0.00012 20.9 0.0 0.00023 19.9 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) O-FucT PF10250.4 EAU89478.2 - 3.9e-08 32.7 0.0 1.9e-07 30.5 0.0 2.0 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase RRM_1 PF00076.17 EAU89480.2 - 2.1e-28 97.7 0.0 1.5e-13 50.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89480.2 - 8.4e-19 67.3 0.0 3.7e-10 39.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU89480.2 - 2.8e-10 39.8 0.0 1.7e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 EAU89480.2 - 0.19 11.7 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family MMR_HSR1 PF01926.18 EAU89481.2 - 2.5e-09 37.0 0.0 4.5e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU89481.2 - 3.1e-09 36.2 0.0 4.5e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EAU89481.2 - 7.9e-06 25.1 0.4 2.7e-05 23.4 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EAU89481.2 - 3.3e-05 23.7 2.8 0.037 13.8 0.1 2.6 2 1 1 3 3 3 2 Dynamin family GBP PF02263.14 EAU89481.2 - 4.3e-05 22.6 0.0 8.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.22 EAU89481.2 - 7e-05 23.1 0.0 0.00013 22.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Septin PF00735.13 EAU89481.2 - 0.00088 18.3 0.0 0.0019 17.2 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_17 PF13207.1 EAU89481.2 - 0.003 18.3 2.0 0.015 16.1 0.5 2.7 1 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAU89481.2 - 0.0034 16.8 0.3 0.0092 15.4 0.2 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EAU89481.2 - 0.0051 16.9 0.4 0.048 13.8 0.3 2.3 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EAU89481.2 - 0.007 16.8 0.0 0.021 15.2 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein MobB PF03205.9 EAU89481.2 - 0.012 15.3 0.8 0.099 12.3 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EAU89481.2 - 0.029 14.2 0.0 0.085 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAU89481.2 - 0.031 13.7 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EAU89481.2 - 0.034 13.0 0.1 0.078 11.8 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 EAU89481.2 - 0.044 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EAU89481.2 - 0.055 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EAU89481.2 - 0.06 13.2 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EAU89481.2 - 0.079 12.6 0.2 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 EAU89481.2 - 0.11 11.8 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAU89481.2 - 0.13 12.2 0.5 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAU89481.2 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 EAU89481.2 - 0.48 10.1 3.3 4.5 7.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EAU89481.2 - 0.97 9.7 0.0 0.97 9.7 0.0 2.1 2 1 0 2 2 1 0 AAA domain GFA PF04828.9 EAU89484.1 - 1.2e-16 60.3 0.1 1.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 EAU89484.1 - 0.11 12.8 3.9 8.1 6.8 2.7 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-NADH-PPase PF09297.6 EAU89484.1 - 8.7 5.9 9.1 0.53 9.8 0.5 2.6 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain UPF0220 PF05255.6 EAU89485.1 - 1.9e-50 170.3 0.0 2.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ABC2_membrane_4 PF12730.2 EAU89485.1 - 2.5 7.2 8.6 0.081 12.0 1.0 1.9 2 1 0 2 2 2 0 ABC-2 family transporter protein Oxidored_FMN PF00724.15 EAU89487.1 - 1.1e-72 244.8 0.0 1.3e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Arrestin_N PF00339.24 EAU89489.2 - 0.00059 19.6 3.8 0.18 11.6 0.3 3.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 EAU89490.1 - 4.2e-05 23.4 0.1 0.00033 20.4 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Metallophos PF00149.23 EAU89491.1 - 7.8e-10 38.4 0.0 1.6e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.21 EAU89492.1 - 7e-31 106.4 0.8 1.1e-30 105.8 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU89492.1 - 1.3e-27 95.6 2.9 2.5e-27 94.7 2.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EAU89492.1 - 0.00025 21.9 0.2 0.00046 21.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_8 PF13183.1 EAU89492.1 - 0.21 11.6 2.8 2.6 8.1 2.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Malic_M PF03949.10 EAU89493.2 - 5e-83 278.5 0.0 6.7e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EAU89493.2 - 1.2e-65 220.4 0.0 6.7e-42 143.1 0.0 2.3 2 0 0 2 2 2 2 Malic enzyme, N-terminal domain adh_short PF00106.20 EAU89495.2 - 7.1e-22 78.0 0.4 1.4e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EAU89495.2 - 2.7e-08 33.7 0.0 1.9e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EAU89495.2 - 1.3e-07 31.6 0.0 8.1e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EAU89495.2 - 0.00025 20.7 0.1 0.00045 19.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EAU89495.2 - 0.0057 16.1 0.0 0.075 12.4 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EAU89495.2 - 0.1 12.5 0.2 0.32 10.9 0.1 1.9 1 1 0 1 1 1 0 NADH(P)-binding ADH_N PF08240.7 EAU89496.1 - 1.9e-28 98.3 2.1 4.8e-28 97.0 1.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU89496.1 - 5.9e-24 84.0 0.0 1.1e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU89496.1 - 2.2e-08 35.0 0.0 7.1e-08 33.3 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EAU89496.1 - 0.0016 19.0 0.0 0.0031 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU89496.1 - 0.0054 17.1 0.1 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EAU89496.1 - 0.0087 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Gp_dh_N PF00044.19 EAU89496.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EAU89496.1 - 0.036 13.4 0.1 0.061 12.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.8 EAU89496.1 - 0.038 13.1 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 EAU89496.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein TrkA_N PF02254.13 EAU89496.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Dus PF01207.12 EAU89497.2 - 2.5e-54 184.2 0.0 3.1e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EAU89497.2 - 0.023 13.9 0.0 0.043 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein GRAB PF10375.4 EAU89498.2 - 6.4e-07 28.7 0.7 1.4e-06 27.6 0.5 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.15 EAU89498.2 - 0.0013 18.2 0.4 0.0044 16.5 0.0 2.1 2 0 0 2 2 2 1 GRIP domain Bacillus_HBL PF05791.6 EAU89498.2 - 6.5 6.0 20.8 0.16 11.2 1.1 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) F-box PF00646.28 EAU89499.2 - 1.2e-06 28.0 1.4 3.3e-06 26.6 1.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU89499.2 - 2.2e-06 27.3 1.3 5.1e-06 26.1 0.9 1.6 1 0 0 1 1 1 1 F-box-like RNA_pol_3_Rpc31 PF11705.3 EAU89500.1 - 4.8e-26 92.1 31.2 1.8e-25 90.2 21.6 1.7 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RRM_1 PF00076.17 EAU89501.1 - 2.4e-14 52.7 0.0 3.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89501.1 - 1.1e-10 41.2 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EAU89501.1 - 5.5e-07 29.9 0.3 5.5e-07 29.9 0.2 2.9 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EAU89501.1 - 3.9e-06 26.5 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sterol_MT_C PF08498.5 EAU89502.1 - 8.4e-27 92.9 0.0 1.2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 EAU89502.1 - 2.8e-19 69.2 0.0 4.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU89502.1 - 7.3e-18 64.8 0.0 1.3e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAU89502.1 - 8e-14 51.3 0.1 1.3e-13 50.6 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EAU89502.1 - 1.3e-13 50.9 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU89502.1 - 1.8e-13 51.0 0.0 5e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU89502.1 - 2.4e-12 46.9 0.0 5.9e-12 45.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU89502.1 - 8.6e-12 45.3 0.0 2.5e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU89502.1 - 3.8e-11 43.2 0.0 6.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU89502.1 - 1.5e-08 34.0 0.0 2.5e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EAU89502.1 - 2.1e-05 23.9 0.0 4.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 EAU89502.1 - 3e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 EAU89502.1 - 6e-05 22.6 0.0 9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 EAU89502.1 - 0.00019 20.5 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 EAU89502.1 - 0.00019 21.0 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EAU89502.1 - 0.0015 19.3 0.0 0.0051 17.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EAU89502.1 - 0.004 16.3 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.7 EAU89502.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Met_10 PF02475.11 EAU89502.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.8 EAU89502.1 - 0.034 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EAU89502.1 - 0.04 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NMT1 PF09084.6 EAU89502.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like PAT1 PF09770.4 EAU89503.2 - 1 7.4 26.7 1.4 7.1 18.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EAU89503.2 - 5.4 6.8 19.3 8.1 6.2 13.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKN1 PF03935.10 EAU89504.2 - 9.8e-191 634.2 0.1 1.1e-190 634.0 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EAU89504.2 - 2.4e-07 30.2 0.0 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Arrestin_N PF00339.24 EAU89506.2 - 5.4e-05 23.0 4.0 0.0002 21.1 0.3 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SWIRM PF04433.12 EAU89507.2 - 8.4e-35 118.7 0.0 8.4e-35 118.7 0.0 2.0 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 EAU89507.2 - 6.6e-08 32.5 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EAU89507.2 - 3.4e-07 29.7 3.0 5.8e-07 28.9 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EAU89507.2 - 1.9e-06 27.8 0.0 4.5e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_37 PF13744.1 EAU89507.2 - 0.24 11.2 3.2 0.57 10.0 2.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain EF-hand_4 PF12763.2 EAU89508.1 - 4.7e-32 109.8 0.1 1.5e-10 40.7 0.0 3.9 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EAU89508.1 - 6.8e-07 28.1 0.0 0.0088 15.2 0.0 4.4 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 EAU89508.1 - 9.8e-06 25.6 4.1 0.14 12.2 0.0 4.5 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.1 EAU89508.1 - 1.5e-05 24.4 0.1 0.12 12.2 0.0 4.3 4 0 0 4 4 3 1 EF-hand domain Seryl_tRNA_N PF02403.17 EAU89508.1 - 0.00036 20.5 4.2 0.00036 20.5 2.9 4.8 2 1 1 4 4 2 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EAU89508.1 - 0.0094 15.5 67.2 0.18 11.3 15.0 4.0 2 1 2 4 4 4 2 IncA protein Myosin_tail_1 PF01576.14 EAU89508.1 - 0.012 13.3 57.0 0.021 12.5 39.4 1.4 1 1 0 1 1 1 0 Myosin tail EF-hand_8 PF13833.1 EAU89508.1 - 0.019 14.5 0.0 0.62 9.7 0.0 3.2 3 1 1 4 4 4 0 EF-hand domain pair Reo_sigmaC PF04582.7 EAU89508.1 - 0.099 11.8 16.6 0.24 10.5 1.8 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein HSBP1 PF06825.7 EAU89508.1 - 0.1 12.1 14.5 0.6 9.7 1.1 3.8 4 0 0 4 4 3 0 Heat shock factor binding protein 1 DivIC PF04977.10 EAU89508.1 - 0.13 11.7 47.5 0.32 10.5 3.9 6.6 2 1 5 7 7 7 0 Septum formation initiator AAA_13 PF13166.1 EAU89508.1 - 0.42 9.0 37.4 0.098 11.1 17.0 2.2 1 1 1 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 EAU89508.1 - 1.2 9.0 60.8 8.1 6.3 7.7 3.9 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 EAU89508.1 - 1.8 8.0 47.7 0.099 12.1 6.1 4.4 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Tropomyosin_1 PF12718.2 EAU89508.1 - 2 8.2 58.7 7.3 6.4 5.1 4.5 1 1 2 3 3 3 0 Tropomyosin like TMF_DNA_bd PF12329.3 EAU89508.1 - 3.7 7.4 50.7 1 9.2 0.8 6.0 4 1 3 7 7 6 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EAU89508.1 - 3.8 6.4 55.9 0.97 8.4 10.3 3.3 1 1 2 3 3 3 0 Autophagy protein Apg6 DUF2353 PF09789.4 EAU89508.1 - 5.5 6.1 46.6 0.31 10.2 7.1 3.9 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) GAS PF13851.1 EAU89508.1 - 6.1 5.9 54.5 0.036 13.2 9.2 4.6 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 EAU89508.1 - 8.2 5.9 62.3 0.64 9.5 9.2 4.7 1 1 2 4 4 4 0 Coiled-coil region of CCDC155 Mito_carr PF00153.22 EAU89509.2 - 1e-67 223.8 3.3 1.2e-21 76.1 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Stn1 PF10451.4 EAU89509.2 - 1.1e-07 30.9 0.1 5.5e-07 28.6 0.1 2.0 1 1 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EAU89509.2 - 0.12 12.2 0.7 0.37 10.6 0.5 1.8 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Rad52_Rad22 PF04098.10 EAU89510.2 - 1.9e-59 199.7 0.1 3.6e-59 198.9 0.0 1.5 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ABC_tran PF00005.22 EAU89511.1 - 8.9e-50 168.5 0.0 3e-30 105.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EAU89511.1 - 7e-35 120.7 22.7 1.5e-18 67.1 1.2 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EAU89511.1 - 2e-09 37.0 1.7 0.00076 18.7 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EAU89511.1 - 1.6e-06 27.6 0.1 0.021 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAU89511.1 - 9.9e-05 21.7 0.8 0.14 11.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EAU89511.1 - 0.0017 18.4 5.2 0.64 9.9 0.0 3.8 4 1 0 4 4 3 1 AAA domain AAA_10 PF12846.2 EAU89511.1 - 0.003 17.0 0.1 2.1 7.7 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EAU89511.1 - 0.003 17.0 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 EAU89511.1 - 0.0072 16.6 0.7 2.6 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAU89511.1 - 0.009 16.1 0.2 11 6.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAU89511.1 - 0.012 15.6 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EAU89511.1 - 0.035 13.0 0.0 0.79 8.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 EAU89511.1 - 0.043 12.9 0.3 5.5 6.0 0.0 2.4 2 0 0 2 2 2 0 KaiC DUF87 PF01935.12 EAU89511.1 - 0.073 12.8 0.1 0.073 12.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Miro PF08477.8 EAU89511.1 - 0.082 13.3 0.2 18 5.8 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein DUF258 PF03193.11 EAU89511.1 - 0.19 10.8 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EAU89511.1 - 0.78 10.0 2.9 21 5.4 0.3 3.2 3 0 0 3 3 3 0 AAA domain ShK PF01549.19 EAU89512.2 - 1.6e-17 63.5 25.6 2.7e-09 37.2 4.6 3.0 3 0 0 3 3 3 2 ShK domain-like Homoserine_dh PF00742.14 EAU89513.1 - 8.1e-47 159.1 0.0 1.5e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EAU89513.1 - 6e-17 62.1 0.0 1.1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain SKN1 PF03935.10 EAU89514.2 - 7.7e-194 644.5 0.2 9.2e-194 644.2 0.1 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) AIG1 PF04548.11 EAU89516.2 - 1.1e-09 37.6 0.0 1.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EAU89516.2 - 3.3e-08 33.4 0.0 7.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAU89516.2 - 0.00018 20.7 0.0 0.00038 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EAU89516.2 - 0.00056 19.0 0.0 0.00096 18.2 0.0 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 EAU89516.2 - 0.00063 19.6 0.1 1.6 8.5 0.0 3.2 2 1 1 3 3 3 2 Dynamin family AAA_29 PF13555.1 EAU89516.2 - 0.017 14.6 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EAU89516.2 - 0.069 13.2 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EAU89516.2 - 0.086 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EAU89516.2 - 0.097 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GBP PF02263.14 EAU89516.2 - 0.13 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_10 PF12846.2 EAU89516.2 - 0.18 11.2 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain DNA_pol3_alpha PF07733.7 EAU89516.2 - 0.19 10.1 0.0 0.33 9.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha subunit AAA_23 PF13476.1 EAU89516.2 - 0.24 11.6 0.4 1.4 9.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain Phage_GP20 PF06810.6 EAU89517.2 - 0.0062 15.9 4.9 0.0062 15.9 3.4 3.1 1 1 2 3 3 3 1 Phage minor structural protein GP20 HAUS-augmin3 PF14932.1 EAU89517.2 - 0.021 14.0 17.2 0.22 10.6 2.8 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Sec66 PF09802.4 EAU89517.2 - 0.044 13.1 4.5 0.072 12.4 3.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 DHC_N2 PF08393.8 EAU89517.2 - 0.087 11.3 6.1 0.022 13.2 2.3 1.4 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 Tropomyosin PF00261.15 EAU89517.2 - 0.096 11.7 20.6 0.064 12.3 0.8 2.7 2 1 0 2 2 2 0 Tropomyosin Macoilin PF09726.4 EAU89517.2 - 0.17 10.1 24.1 0.48 8.6 16.6 1.5 1 1 0 1 1 1 0 Transmembrane protein Bacillus_HBL PF05791.6 EAU89517.2 - 0.25 10.6 6.2 0.054 12.8 0.9 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 EAU89517.2 - 0.26 10.4 27.5 0.99 8.5 0.7 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EAU89517.2 - 0.49 10.7 21.7 0.43 10.9 3.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF445 PF04286.7 EAU89517.2 - 0.56 9.6 7.8 0.76 9.2 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Laminin_II PF06009.7 EAU89517.2 - 0.82 9.4 14.0 0.53 10.0 0.8 3.1 1 1 0 2 2 2 0 Laminin Domain II Pox_A_type_inc PF04508.7 EAU89517.2 - 0.97 9.3 16.5 3.6 7.6 0.6 4.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.7 EAU89517.2 - 1.3 9.3 6.2 69 3.7 2.8 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 EAU89517.2 - 1.6 8.6 24.3 3.8 7.3 9.8 2.9 1 1 0 2 2 2 0 Tropomyosin like DUF4140 PF13600.1 EAU89517.2 - 1.7 9.1 23.3 0.46 10.9 0.7 3.7 1 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Baculo_PEP_C PF04513.7 EAU89517.2 - 2.3 8.0 9.7 14 5.4 0.3 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rootletin PF15035.1 EAU89517.2 - 2.4 8.0 27.2 1.5e+04 -5.0 18.9 3.6 1 1 0 1 1 0 0 Ciliary rootlet component, centrosome cohesion SlyX PF04102.7 EAU89517.2 - 2.7 8.4 20.4 0.59 10.5 0.8 4.1 2 2 1 3 3 3 0 SlyX Adeno_PIX PF03955.9 EAU89517.2 - 3.4 8.2 10.7 1.4 9.4 0.1 3.1 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) TPR_MLP1_2 PF07926.7 EAU89517.2 - 4 7.1 24.9 30 4.3 1.0 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 EAU89517.2 - 4.3 6.5 20.0 8.1 5.6 6.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.14 EAU89517.2 - 4.4 5.0 15.9 2.5 5.8 8.8 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 EAU89517.2 - 4.8 5.8 16.4 0.76 8.4 8.1 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ADIP PF11559.3 EAU89517.2 - 5.6 6.8 32.0 2.6 7.9 6.7 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Med9 PF07544.8 EAU89517.2 - 6 6.6 17.0 8.7 6.1 0.9 3.5 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FlxA PF14282.1 EAU89517.2 - 7.8 6.5 17.7 57 3.7 0.1 3.2 2 1 0 2 2 2 0 FlxA-like protein DUF4094 PF13334.1 EAU89517.2 - 8.7 6.8 15.8 1.6 9.1 1.0 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) DUF2935 PF11155.3 EAU89517.2 - 9.6 6.3 7.4 9.7 6.3 2.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF4186 PF13811.1 EAU89518.1 - 0.047 13.4 0.2 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) Peptidase_C50 PF03568.12 EAU89520.1 - 4.3e-85 285.7 0.0 7.7e-85 284.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EAU89520.1 - 1.9e-08 34.1 12.5 0.0016 18.2 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU89520.1 - 3.1e-07 29.6 7.5 0.59 10.0 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU89520.1 - 2.4e-06 27.0 7.2 0.13 11.9 0.0 5.1 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 EAU89520.1 - 6.1e-05 22.6 17.9 4 7.5 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 EAU89520.1 - 0.046 13.6 9.7 3.2 7.8 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAU89520.1 - 0.3 11.7 21.4 0.044 14.4 1.3 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU89520.1 - 1.8 9.2 0.0 1.8 9.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU89522.1 - 6.3e-19 67.6 0.0 0.051 13.5 0.0 8.7 2 1 6 8 8 8 5 Tetratricopeptide repeat NACHT PF05729.7 EAU89522.1 - 1.1e-08 34.8 0.0 5.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 NACHT domain TPR_2 PF07719.12 EAU89522.1 - 1.1e-07 31.1 1.3 1.1e+02 3.0 0.0 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU89522.1 - 4.4e-07 29.6 6.1 5.3 7.1 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat DnaB_bind PF10410.4 EAU89522.1 - 1.1e-06 28.5 12.6 3.6 7.6 0.0 7.3 7 0 0 7 7 7 3 DnaB-helicase binding domain of primase Arch_ATPase PF01637.13 EAU89522.1 - 1.3e-05 25.0 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EAU89522.1 - 2.8e-05 24.2 0.1 0.00016 21.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.1 EAU89522.1 - 3.4e-05 24.0 21.4 66 4.5 0.1 10.6 7 2 4 11 11 10 0 Tetratricopeptide repeat NB-ARC PF00931.17 EAU89522.1 - 4e-05 22.6 0.0 7.6e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.17 EAU89522.1 - 0.0076 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EAU89522.1 - 0.017 15.2 0.0 0.13 12.4 0.0 2.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EAU89522.1 - 0.054 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 EAU89522.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain She2p PF11435.3 EAU89522.1 - 0.21 10.9 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein She2p TPR_12 PF13424.1 EAU89523.2 - 2.2e-09 37.1 0.1 0.067 13.1 0.0 5.9 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EAU89523.2 - 1.7e-08 33.9 0.0 0.079 12.6 0.0 5.5 3 2 3 6 6 6 2 TPR repeat NACHT PF05729.7 EAU89523.2 - 1.6e-07 31.1 0.0 3.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EAU89523.2 - 5e-06 25.5 0.0 8.3e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 EAU89523.2 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase TPR_10 PF13374.1 EAU89523.2 - 1.4e-05 24.8 5.0 0.36 10.8 0.1 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat AAA_16 PF13191.1 EAU89523.2 - 6.5e-05 22.9 0.0 0.00033 20.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.12 EAU89523.2 - 0.0003 20.4 0.0 1.4e+02 2.7 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat RNA_helicase PF00910.17 EAU89523.2 - 0.0031 17.6 0.0 0.0078 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EAU89523.2 - 0.0066 16.5 0.1 0.06 13.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU89523.2 - 0.018 14.8 0.2 0.58 9.9 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain Complex1_LYR PF05347.10 EAU89523.2 - 0.023 14.4 0.1 5.1 6.9 0.0 3.8 3 0 0 3 3 3 0 Complex 1 protein (LYR family) AAA_30 PF13604.1 EAU89523.2 - 0.027 14.0 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.1 EAU89523.2 - 0.03 12.9 0.0 0.74 8.3 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 EAU89523.2 - 0.047 13.2 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EAU89523.2 - 0.052 13.2 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 NTPase Complex1_LYR_1 PF13232.1 EAU89523.2 - 0.07 13.3 0.1 15 5.9 0.0 4.1 3 1 0 3 3 3 0 Complex1_LYR-like MobB PF03205.9 EAU89523.2 - 0.074 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EAU89523.2 - 0.2 10.7 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Lustrin_cystein PF14625.1 EAU89525.2 - 0.0035 17.3 0.7 0.0043 17.0 0.5 1.2 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Granulin PF00396.13 EAU89525.2 - 0.088 12.9 1.8 0.12 12.5 1.2 1.2 1 0 0 1 1 1 0 Granulin PIF1 PF05970.9 EAU89526.2 - 8.2e-72 242.1 0.0 6.5e-70 235.8 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAU89526.2 - 3.5e-46 157.2 0.0 7.9e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU89526.2 - 1e-09 38.2 0.0 3.7e-09 36.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EAU89526.2 - 1.8e-06 27.5 0.3 5e-05 22.9 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain Herpes_Helicase PF02689.9 EAU89526.2 - 1.4e-05 23.0 0.0 0.018 12.7 0.0 2.1 2 0 0 2 2 2 2 Helicase Viral_helicase1 PF01443.13 EAU89526.2 - 2.2e-05 24.1 0.2 0.023 14.2 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EAU89526.2 - 0.00012 21.1 0.0 0.00051 19.1 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EAU89526.2 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU89526.2 - 0.002 18.2 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU89526.2 - 0.0024 18.6 0.1 0.022 15.5 0.0 2.8 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 EAU89526.2 - 0.0037 16.9 0.0 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EAU89526.2 - 0.012 15.3 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EAU89526.2 - 0.012 15.7 0.1 0.047 13.8 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EAU89526.2 - 0.015 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 EAU89526.2 - 0.015 15.3 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Phage_GPA PF05840.8 EAU89526.2 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) UPF0079 PF02367.12 EAU89526.2 - 0.036 13.6 0.2 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EAU89526.2 - 0.039 13.8 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EAU89526.2 - 0.039 13.6 0.0 0.15 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EAU89526.2 - 0.056 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 NTPase CbiA PF01656.18 EAU89526.2 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EAU89526.2 - 0.072 13.3 0.1 0.3 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EAU89526.2 - 0.077 13.2 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EAU89526.2 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.4 EAU89526.2 - 0.11 11.1 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Thymidylate_kin PF02223.12 EAU89526.2 - 0.12 11.7 0.0 0.31 10.3 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase AAA_11 PF13086.1 EAU89526.2 - 0.21 11.1 0.1 0.96 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Cauli_VI PF01693.11 EAU89530.1 - 1.3e-10 41.0 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin TGT_C1 PF14809.1 EAU89532.2 - 0.026 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 C1 domain of tRNA-guanine transglycosylase dimerisation DUF605 PF04652.11 EAU89533.1 - 0.69 9.2 14.6 1.1 8.5 10.1 1.4 1 0 0 1 1 1 0 Vta1 like Lustrin_cystein PF14625.1 EAU89534.1 - 0.0014 18.6 2.2 0.0026 17.7 1.6 1.4 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain Granulin PF00396.13 EAU89534.1 - 0.014 15.4 1.2 0.028 14.5 0.8 1.5 1 0 0 1 1 1 0 Granulin Glypican PF01153.14 EAU89534.1 - 0.36 9.3 1.2 0.33 9.4 0.8 1.1 1 0 0 1 1 1 0 Glypican MF_alpha_N PF05436.6 EAU89535.1 - 0.1 12.2 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Rho_N PF07498.7 EAU89536.2 - 9.8e-06 25.2 0.5 3.2e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain FYVE PF01363.16 EAU89536.2 - 0.0023 17.7 0.3 0.0056 16.5 0.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF572 PF04502.8 EAU89536.2 - 0.0052 16.0 6.9 0.0076 15.5 4.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Armet PF10208.4 EAU89536.2 - 0.009 15.6 0.1 0.31 10.6 0.1 2.2 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Zn_Tnp_IS91 PF14319.1 EAU89536.2 - 0.02 14.4 0.8 0.068 12.6 0.5 1.9 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C3HC4_3 PF13920.1 EAU89536.2 - 0.19 11.4 0.2 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.9 EAU89536.2 - 0.22 9.4 6.3 0.31 9.0 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.9 EAU89536.2 - 0.93 8.2 7.7 1.4 7.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Hid1 PF12722.2 EAU89536.2 - 4.3 4.9 7.9 5.7 4.4 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DREPP PF05558.7 EAU89536.2 - 5.3 6.8 11.5 8.1 6.2 8.0 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Asp-B-Hydro_N PF05279.6 EAU89536.2 - 8.9 6.0 13.0 13 5.5 9.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region His_Phos_1 PF00300.17 EAU89537.2 - 7.5e-14 52.1 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Macoilin PF09726.4 EAU89538.2 - 9 4.4 8.4 13 3.9 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Syntaxin-6_N PF09177.6 EAU89539.1 - 1.2e-22 80.0 11.4 2.3e-22 79.2 0.9 2.6 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 EAU89539.1 - 2.1e-15 56.1 6.1 2.1e-15 56.1 4.2 2.5 3 0 0 3 3 2 1 SNARE domain Bacillus_HBL PF05791.6 EAU89539.1 - 0.0015 17.9 4.2 0.07 12.4 0.1 3.1 3 0 0 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) FlaC_arch PF05377.6 EAU89539.1 - 0.0044 16.8 7.1 2.9 7.8 0.1 3.5 3 1 0 3 3 3 1 Flagella accessory protein C (FlaC) CCDC142 PF14923.1 EAU89539.1 - 0.0046 15.3 0.1 0.007 14.7 0.1 1.3 1 0 0 1 1 1 1 Coiled-coil protein 142 HisKA_3 PF07730.8 EAU89539.1 - 0.0071 16.6 0.4 0.0071 16.6 0.3 3.0 2 1 0 2 2 2 1 Histidine kinase Laminin_I PF06008.9 EAU89539.1 - 0.0098 15.2 1.5 0.0098 15.2 1.1 2.6 2 1 0 2 2 2 1 Laminin Domain I UBN2 PF14223.1 EAU89539.1 - 0.024 14.4 3.7 0.29 10.9 0.1 2.8 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Cortex-I_coil PF09304.5 EAU89539.1 - 0.027 14.4 13.4 0.1 12.6 1.9 2.4 2 1 0 2 2 2 0 Cortexillin I, coiled coil Cwf_Cwc_15 PF04889.7 EAU89539.1 - 0.035 13.8 7.0 0.045 13.4 4.7 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein IFT57 PF10498.4 EAU89539.1 - 0.039 12.6 8.5 0.42 9.2 1.2 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 FliJ PF02050.11 EAU89539.1 - 0.041 13.9 9.6 1.8 8.6 1.8 3.0 2 2 1 3 3 3 0 Flagellar FliJ protein COG2 PF06148.6 EAU89539.1 - 0.045 13.6 8.8 2.9 7.7 0.2 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3584 PF12128.3 EAU89539.1 - 0.061 10.6 12.1 0.23 8.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DHC_N1 PF08385.7 EAU89539.1 - 0.082 11.2 3.5 0.064 11.6 0.2 1.9 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 Reo_sigmaC PF04582.7 EAU89539.1 - 0.086 11.9 7.4 0.29 10.2 1.8 2.3 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF3259 PF11652.3 EAU89539.1 - 0.091 12.9 1.3 4.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3259) Spc7 PF08317.6 EAU89539.1 - 0.11 11.1 11.2 0.22 10.1 1.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.7 EAU89539.1 - 0.29 10.8 9.0 0.1 12.3 0.3 2.9 2 1 0 3 3 3 0 Laminin Domain II DUF1664 PF07889.7 EAU89539.1 - 0.43 10.3 7.6 1.5 8.6 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EAU89539.1 - 0.48 9.9 12.1 2.8 7.4 1.5 2.7 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4618 PF15397.1 EAU89539.1 - 0.75 9.0 6.9 5.2 6.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Snapin_Pallidin PF14712.1 EAU89539.1 - 0.75 10.1 7.1 4 7.8 0.6 2.9 2 1 0 2 2 2 0 Snapin/Pallidin Prominin PF05478.6 EAU89539.1 - 0.77 7.2 5.0 0.92 6.9 0.6 2.2 1 1 0 2 2 2 0 Prominin AAA_13 PF13166.1 EAU89539.1 - 0.81 8.0 8.4 4.9 5.4 4.6 1.9 1 1 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.3 EAU89539.1 - 0.87 9.4 10.2 2 8.3 0.8 3.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RmuC PF02646.11 EAU89539.1 - 1 8.1 7.2 0.34 9.6 0.5 2.5 2 1 1 3 3 3 0 RmuC family DUF4201 PF13870.1 EAU89539.1 - 1.1 8.7 9.9 0.91 8.9 0.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4375 PF14300.1 EAU89539.1 - 1.7 8.6 4.2 5.1 7.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) NPV_P10 PF05531.7 EAU89539.1 - 1.8 8.9 8.2 19 5.5 0.1 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Phage_GPO PF05929.6 EAU89539.1 - 2 7.6 10.0 1.1 8.4 0.9 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.4 EAU89539.1 - 3.3 6.5 13.3 9.9 5.0 0.2 2.9 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 SPX PF03105.14 EAU89539.1 - 3.4 7.3 8.3 5.1 6.7 5.8 1.3 1 0 0 1 1 1 0 SPX domain Microtub_assoc PF07989.6 EAU89539.1 - 3.4 7.5 5.3 4.2 7.2 0.1 3.1 3 1 0 3 3 3 0 Microtubule associated Phage_GP20 PF06810.6 EAU89539.1 - 3.7 6.9 7.6 1.7 8.0 0.4 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 EAU89539.1 - 4.7 7.2 8.6 1.4 9.0 0.2 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.1 EAU89539.1 - 5.7 6.9 8.4 2.9 7.8 1.0 3.1 2 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 SlyX PF04102.7 EAU89539.1 - 6.3 7.2 13.3 22 5.5 0.7 3.8 2 2 1 3 3 3 0 SlyX Fib_alpha PF08702.5 EAU89539.1 - 6.4 6.8 9.7 1.7e+02 2.2 3.8 3.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Adeno_PIX PF03955.9 EAU89539.1 - 7.9 7.0 9.7 5.3 7.6 0.5 2.9 2 1 2 4 4 4 0 Adenovirus hexon-associated protein (IX) DUF641 PF04859.7 EAU89539.1 - 8.7 6.1 9.8 3.8 7.2 0.5 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) PHD PF00628.24 EAU89540.2 - 6.1e-08 32.2 1.8 1.3e-07 31.2 1.2 1.5 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.19 EAU89540.2 - 1.4e-05 24.6 0.2 4.5e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FMO-like PF00743.14 EAU89541.1 - 6.7e-39 133.4 0.0 8.2e-29 100.1 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EAU89541.1 - 8e-16 58.7 0.0 2.1e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU89541.1 - 2e-08 34.1 0.0 1.4e-05 24.8 0.0 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EAU89541.1 - 4.3e-07 29.1 0.0 0.0001 21.3 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EAU89541.1 - 0.0001 22.2 0.0 0.00057 19.8 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU89541.1 - 0.00096 19.1 0.1 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAU89541.1 - 0.0025 16.3 0.0 1.5 7.1 0.0 3.5 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.12 EAU89541.1 - 0.0078 15.3 0.4 0.16 11.0 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.15 EAU89541.1 - 0.022 14.8 0.1 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EAU89541.1 - 0.043 12.7 0.1 5.1 5.9 0.0 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU89541.1 - 0.062 12.3 0.8 5.1 6.0 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NDUF_B5 PF09781.4 EAU89542.1 - 0.75 9.0 4.6 1.5 8.0 3.2 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF1675 PF07897.6 EAU89542.1 - 3.1 7.5 17.8 6.5 6.5 12.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MIP-T3 PF10243.4 EAU89542.1 - 4.3 5.6 32.1 6.2 5.1 22.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BTV_NS2 PF04514.7 EAU89542.1 - 7.1 5.4 12.5 9.8 4.9 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 p450 PF00067.17 EAU89543.2 - 1.7e-57 194.9 0.0 3.6e-57 193.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Nop14 PF04147.7 EAU89544.1 - 0.054 11.4 8.4 0.069 11.0 5.8 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EAU89544.1 - 0.061 11.6 9.3 0.089 11.1 6.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.4 EAU89544.1 - 0.062 12.0 7.8 0.095 11.4 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop25 PF09805.4 EAU89544.1 - 0.098 12.7 5.4 0.16 12.0 3.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) TRAP_alpha PF03896.11 EAU89544.1 - 0.47 9.3 5.9 0.88 8.5 4.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit F-protein PF00469.15 EAU89544.1 - 0.6 9.4 3.4 1 8.6 2.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Daxx PF03344.10 EAU89544.1 - 2.4 6.5 10.4 3.5 5.9 7.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EAU89544.1 - 9.4 4.1 13.4 14 3.5 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_12 PF13424.1 EAU89546.2 - 3.5e-09 36.4 5.5 1.2 9.1 0.1 7.1 1 1 6 7 7 7 3 Tetratricopeptide repeat Arch_ATPase PF01637.13 EAU89546.2 - 3.2e-06 27.0 0.0 7.2e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EAU89546.2 - 8e-06 25.6 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU89546.2 - 8.8e-05 22.5 0.0 0.00052 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAU89546.2 - 0.00015 20.7 0.0 0.00027 19.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.1 EAU89546.2 - 0.00019 21.0 0.2 3.4 7.4 0.0 4.9 4 1 1 5 5 5 1 TPR repeat RNA_helicase PF00910.17 EAU89546.2 - 0.0094 16.1 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 EAU89546.2 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EAU89546.2 - 0.023 14.8 0.0 0.11 12.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain FA_FANCE PF11510.3 EAU89546.2 - 0.04 13.0 0.1 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE AAA_35 PF14516.1 EAU89546.2 - 0.087 11.4 0.0 0.21 10.1 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 EAU89546.2 - 0.14 11.9 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 NTPase DUF4404 PF14357.1 EAU89546.2 - 0.36 11.2 3.9 1.2 9.6 0.0 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4404) TPR_10 PF13374.1 EAU89546.2 - 0.43 10.5 4.1 20 5.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C14 PF00656.17 EAU89549.1 - 3.3e-17 63.0 0.0 4.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Formyl_trans_N PF00551.14 EAU89550.2 - 1.3e-20 73.6 0.0 3.6e-20 72.2 0.0 1.7 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EAU89550.2 - 8.5e-06 25.7 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF2280 PF10045.4 EAU89550.2 - 0.033 14.1 0.0 0.76 9.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2280) SH3_9 PF14604.1 EAU89551.1 - 3.2e-10 39.4 1.8 1e-09 37.8 1.3 1.8 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAU89551.1 - 8.7e-10 37.8 0.4 7.6e-09 34.8 0.3 2.1 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAU89551.1 - 5.7e-09 35.3 0.2 1.6e-08 33.8 0.1 1.8 1 1 0 1 1 1 1 Variant SH3 domain DUF1183 PF06682.7 EAU89551.1 - 2.8 7.4 9.3 0.42 10.1 2.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) ABC_trans_N PF14510.1 EAU89552.1 - 0.045 13.8 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 ABC-transporter extracellular N-terminal RNA_pol_L_2 PF13656.1 EAU89553.2 - 4e-16 58.2 0.0 1.7e-15 56.1 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EAU89553.2 - 1.8e-06 26.9 0.0 1.3e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ADH_zinc_N PF00107.21 EAU89554.2 - 5.3e-25 87.4 0.1 1.1e-24 86.4 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU89554.2 - 9.5e-15 55.6 0.1 1.7e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU89554.2 - 2.3e-10 40.2 0.0 4.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GRIM-19 PF06212.7 EAU89554.2 - 0.017 14.7 0.0 1 9.0 0.0 2.5 3 0 0 3 3 3 0 GRIM-19 protein EamA PF00892.15 EAU89555.1 - 1.7e-24 86.2 29.0 3.3e-15 56.2 7.5 2.9 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EAU89555.1 - 5.9e-08 32.8 26.5 7.4e-07 29.3 5.3 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EAU89555.1 - 1.1 8.9 18.0 0.062 12.9 7.6 2.5 2 2 0 2 2 2 0 Triose-phosphate Transporter family DUF605 PF04652.11 EAU89556.1 - 1.5 8.1 15.6 1.7 7.9 10.8 1.1 1 0 0 1 1 1 0 Vta1 like Cu-oxidase PF00394.17 EAU89560.1 - 3.2e-46 157.1 0.0 9.6e-42 142.5 0.0 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU89560.1 - 1.1e-37 128.6 8.2 3e-34 117.4 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU89560.1 - 3.6e-36 123.4 1.0 1.1e-34 118.6 0.3 2.9 3 0 0 3 3 3 1 Multicopper oxidase Rep_fac-A_3 PF08661.6 EAU89561.1 - 1.3e-19 70.1 0.0 1.4e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 CMAS PF02353.15 EAU89562.2 - 4.4e-65 219.4 0.3 5.4e-65 219.1 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EAU89562.2 - 3.9e-11 42.9 0.0 2.2e-10 40.5 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU89562.2 - 3.4e-07 30.6 0.0 4e-06 27.2 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain DOT1 PF08123.8 EAU89562.2 - 3.3e-06 26.5 0.0 6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EAU89562.2 - 3.7e-06 27.4 0.0 1.4e-05 25.6 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU89562.2 - 8e-06 25.8 0.0 3.7e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU89562.2 - 2.2e-05 24.8 0.0 5.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU89562.2 - 3e-05 24.3 0.0 0.00039 20.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU89562.2 - 0.00013 21.5 0.0 0.00035 20.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EAU89562.2 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EAU89562.2 - 0.014 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EAU89562.2 - 0.023 14.0 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AA_permease_2 PF13520.1 EAU89563.2 - 2.8e-49 167.8 36.2 3.5e-49 167.5 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EAU89563.2 - 8.9e-15 53.9 31.5 1.6e-14 53.1 21.8 1.4 1 1 0 1 1 1 1 Amino acid permease 6PF2K PF01591.13 EAU89564.2 - 1e-61 207.8 0.0 1.4e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EAU89564.2 - 3.6e-24 85.6 0.0 8.8e-24 84.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EAU89564.2 - 4.3e-07 29.9 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU89564.2 - 0.0014 19.4 0.2 0.0066 17.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EAU89564.2 - 0.0063 15.7 0.0 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.7 EAU89564.2 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 EAU89564.2 - 0.12 11.9 0.1 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 EAU89564.2 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RRM_1 PF00076.17 EAU89565.1 - 1.3e-12 47.1 0.0 2.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89565.1 - 2.4e-08 33.8 0.0 6.8e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EAU89565.1 - 0.00024 21.4 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EAU89565.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRL PF13146.1 EAU89565.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 TRL-like protein family Tub PF01167.13 EAU89565.1 - 0.037 12.9 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Tub family DUF4243 PF14027.1 EAU89568.2 - 0.12 11.8 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) LPP PF04728.8 EAU89569.1 - 0.48 10.2 2.6 0.46 10.3 0.6 1.9 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Transport_MerF PF11431.3 EAU89571.2 - 0.2 11.3 0.7 0.28 10.8 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein MerF Neurensin PF14927.1 EAU89572.2 - 0.11 11.9 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Neurensin Sec23_trunk PF04811.10 EAU89573.2 - 1.5e-75 253.6 0.0 3.5e-75 252.5 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EAU89573.2 - 3.8e-35 119.4 0.3 7e-35 118.5 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EAU89573.2 - 7e-29 100.1 0.1 1.4e-28 99.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EAU89573.2 - 8.6e-17 60.4 6.4 1.6e-16 59.5 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EAU89573.2 - 8.6e-13 47.7 0.1 2.7e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat OPT PF03169.10 EAU89574.2 - 3.3e-70 237.2 29.3 4.2e-40 137.8 4.9 2.2 1 1 0 2 2 2 2 OPT oligopeptide transporter protein Cellulase PF00150.13 EAU89575.2 - 3.9e-07 29.5 0.0 8.9e-07 28.3 0.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Na_H_Exchanger PF00999.16 EAU89576.1 - 4.7e-57 193.2 49.5 7e-57 192.6 34.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GATase PF00117.23 EAU89576.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I HLH PF00010.21 EAU89579.2 - 7.4e-09 35.1 0.0 2.4e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.11 EAU89581.2 - 1.7e-25 89.4 27.9 1.4e-14 53.6 2.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EAU89581.2 - 3e-07 29.2 12.8 1.4e-06 27.0 0.1 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein Tyrosinase PF00264.15 EAU89582.1 - 4.8e-34 118.4 0.0 8.7e-34 117.6 0.0 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase XPG_I PF00867.13 EAU89583.2 - 1.2e-18 66.9 0.0 4e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EAU89583.2 - 1.4e-08 34.9 0.0 1.3e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain DUF3435 PF11917.3 EAU89590.2 - 0.01 14.5 0.3 0.021 13.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3435) DEAD PF00270.24 EAU89591.2 - 1.8e-14 53.6 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU89591.2 - 0.00034 20.5 0.0 0.00083 19.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Tet_JBP PF12851.2 EAU89594.2 - 2.1e-14 53.1 0.0 3.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily FliH PF02108.11 EAU89596.2 - 0.11 12.3 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Flagellar assembly protein FliH p450 PF00067.17 EAU89601.2 - 6.1e-67 226.1 0.0 8.1e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Amino_oxidase PF01593.19 EAU89602.1 - 8.5e-33 114.0 0.0 1.3e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EAU89602.1 - 4.3e-10 39.4 0.5 5.2e-09 35.9 0.2 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAU89602.1 - 0.0016 18.5 0.0 0.004 17.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAU89602.1 - 0.0021 17.1 0.6 0.0072 15.4 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Imm30 PF15594.1 EAU89602.1 - 0.048 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 30 Pyr_redox_2 PF07992.9 EAU89602.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU89602.1 - 0.25 9.7 0.1 0.38 9.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EAU89602.1 - 0.27 10.0 0.2 0.51 9.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EAU89602.1 - 0.33 9.8 1.2 0.55 9.0 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NPCBM_assoc PF10633.4 EAU89603.1 - 0.079 13.0 0.1 0.43 10.6 0.0 2.2 2 1 1 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Dyp_perox PF04261.7 EAU89604.1 - 8.7e-07 27.9 0.0 2.3e-05 23.2 0.0 2.7 3 1 0 3 3 3 2 Dyp-type peroxidase family VWA_2 PF13519.1 EAU89605.2 - 3.1e-10 40.4 0.0 5.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EAU89605.2 - 5.9e-07 29.3 0.0 1.3e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EAU89605.2 - 0.12 12.0 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain MFS_1 PF07690.11 EAU89606.1 - 3.8e-29 101.5 23.7 6.1e-29 100.8 16.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L18e PF00828.14 EAU89607.1 - 1.1e-35 122.7 0.1 1.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_L_2 PF13656.1 EAU89608.1 - 1.5e-23 82.0 0.0 3.2e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EAU89608.1 - 1.6e-13 49.5 0.0 2.3e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 EAU89608.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Rio2, N-terminal IDO PF01231.13 EAU89610.2 - 7.1e-121 403.5 0.0 8.2e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase MMR_HSR1 PF01926.18 EAU89611.2 - 1.2e-09 38.1 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU89611.2 - 0.0082 15.4 0.1 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 EAU89611.2 - 0.01 16.1 0.5 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain Septin PF00735.13 EAU89611.2 - 0.023 13.7 0.1 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 EAU89611.2 - 0.032 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.18 EAU89611.2 - 0.049 12.4 0.1 0.093 11.5 0.1 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 EAU89611.2 - 0.063 14.0 0.1 0.4 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EAU89611.2 - 0.089 12.0 0.0 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF258 PF03193.11 EAU89611.2 - 0.095 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IIGP PF05049.8 EAU89611.2 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Pkinase PF00069.20 EAU89614.2 - 9.1e-68 228.2 0.0 1.3e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89614.2 - 4.3e-33 114.4 0.0 7.7e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU89614.2 - 0.00026 20.7 0.0 0.00083 19.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EAU89614.2 - 0.65 8.7 0.0 0.94 8.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PPR PF01535.15 EAU89615.1 - 0.00051 19.8 0.1 32 4.7 0.0 5.3 5 0 0 5 5 5 2 PPR repeat TPR_7 PF13176.1 EAU89615.1 - 0.02 14.6 1.3 0.12 12.2 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAU89615.1 - 4 8.3 10.0 0.5 11.1 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat p450 PF00067.17 EAU89617.1 - 2.4e-59 201.0 0.0 4.6e-59 200.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU89618.2 - 5e-71 239.5 0.0 6.1e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EAU89619.2 - 1.9e-72 244.3 0.0 2.2e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_US9 PF06072.6 EAU89620.2 - 0.048 13.4 0.1 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ABC_membrane PF00664.18 EAU89622.2 - 2e-85 286.5 29.9 6.6e-44 150.3 6.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAU89622.2 - 2.8e-69 231.6 0.0 3.5e-33 114.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EAU89622.2 - 4.2e-15 55.5 0.3 3.5e-05 23.1 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU89622.2 - 1.1e-11 45.3 0.0 0.013 15.4 0.0 4.3 4 0 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 EAU89622.2 - 1.1e-09 37.4 0.8 0.00049 18.7 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EAU89622.2 - 5e-08 32.3 1.6 0.0078 15.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU89622.2 - 1e-07 32.1 1.8 0.00036 20.5 0.0 3.4 4 0 0 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 EAU89622.2 - 8.2e-06 26.6 0.0 0.057 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EAU89622.2 - 1e-05 25.6 3.4 0.19 11.8 0.1 4.8 3 2 0 3 3 3 2 AAA domain DUF258 PF03193.11 EAU89622.2 - 1.2e-05 24.5 0.1 0.15 11.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EAU89622.2 - 5.6e-05 22.8 2.7 1.8 8.0 0.1 4.6 4 1 0 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EAU89622.2 - 0.00025 20.2 0.1 0.28 10.2 0.0 2.6 3 0 0 3 3 2 2 Zeta toxin SbcCD_C PF13558.1 EAU89622.2 - 0.00026 20.8 2.1 0.79 9.6 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EAU89622.2 - 0.00028 20.7 0.0 0.23 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EAU89622.2 - 0.00083 19.0 0.2 0.54 9.9 0.0 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 EAU89622.2 - 0.001 17.8 4.6 0.016 13.9 0.0 2.7 3 0 0 3 3 2 1 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 EAU89622.2 - 0.0022 17.4 0.1 1.9 7.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_14 PF13173.1 EAU89622.2 - 0.0022 17.8 0.0 2.7 7.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 EAU89622.2 - 0.0032 16.9 0.8 4.5 6.6 0.0 3.4 4 0 0 4 4 3 1 AAA-like domain AAA_25 PF13481.1 EAU89622.2 - 0.0036 16.7 0.1 2.2 7.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EAU89622.2 - 0.0046 17.2 0.0 0.95 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAU89622.2 - 0.012 15.2 0.0 1.8 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EAU89622.2 - 0.013 14.4 0.0 3.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_28 PF13521.1 EAU89622.2 - 0.016 15.1 0.0 3.6 7.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EAU89622.2 - 0.02 14.8 0.0 3.9 7.4 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EAU89622.2 - 0.022 15.0 0.0 3.8 7.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAU89622.2 - 0.034 13.9 0.6 7.1 6.3 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF2628 PF10947.3 EAU89622.2 - 0.05 13.4 0.1 0.05 13.4 0.1 3.9 5 0 0 5 5 3 0 Protein of unknown function (DUF2628) APS_kinase PF01583.15 EAU89622.2 - 0.078 12.6 0.0 5.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_15 PF13175.1 EAU89622.2 - 0.11 11.5 0.0 3.4 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 EAU89622.2 - 0.21 10.3 0.1 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain p450 PF00067.17 EAU89623.1 - 1.1e-69 235.1 0.0 1.4e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_3 PF13920.1 EAU89624.2 - 9.2e-11 41.2 5.4 2.5e-09 36.6 1.0 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU89624.2 - 3.2e-06 27.0 5.0 3.5e-06 26.9 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU89624.2 - 0.00019 21.0 1.3 0.0008 19.0 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU89624.2 - 0.00031 20.5 3.8 0.0031 17.2 0.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EAU89624.2 - 0.0037 16.9 2.7 0.031 13.9 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EAU89624.2 - 4.5 6.9 6.8 0.64 9.6 0.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Pkinase PF00069.20 EAU89626.1 - 0.03 13.4 0.1 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.18 EAU89626.1 - 0.066 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prok_Ub PF14454.1 EAU89626.1 - 0.087 12.4 0.0 0.53 9.9 0.0 2.1 1 1 0 1 1 1 0 Prokaryotic Ubiquitin MR_MLE_C PF13378.1 EAU89627.2 - 1.4e-15 57.2 0.1 2.9e-15 56.1 0.1 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EAU89627.2 - 5.1e-14 52.5 0.1 7.9e-12 45.5 0.0 2.5 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EAU89627.2 - 3.9e-06 26.8 0.0 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EAU89627.2 - 0.007 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Peptidase_C25_C PF03785.9 EAU89627.2 - 0.044 13.5 0.1 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain CHB_HEX_C_1 PF13290.1 EAU89631.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain TMEMspv1-c74-12 PF11044.3 EAU89631.1 - 0.035 13.6 0.2 0.061 12.8 0.2 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein P12 PF12669.2 EAU89631.1 - 0.057 13.6 1.1 0.086 13.0 0.8 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF106 PF01956.11 EAU89631.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 60KD_IMP PF02096.15 EAU89632.1 - 0.00082 19.0 0.8 0.0011 18.7 0.6 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3609 PF12259.3 EAU89632.1 - 0.001 17.8 0.3 0.0015 17.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) 7TM_GPCR_Srh PF10318.4 EAU89632.1 - 0.0012 17.6 1.2 0.0015 17.3 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF912 PF06024.7 EAU89632.1 - 0.0061 16.5 1.4 0.013 15.5 0.3 1.9 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) LRRC37AB_C PF14914.1 EAU89632.1 - 0.0083 15.5 0.3 0.0083 15.5 0.2 1.5 2 0 0 2 2 2 1 LRRC37A/B like protein 1 C-terminal domain Viral_Beta_CD PF04530.7 EAU89632.1 - 0.0095 16.0 1.1 0.12 12.5 0.3 2.1 2 0 0 2 2 2 1 Viral Beta C/D like family Glycophorin_A PF01102.13 EAU89632.1 - 0.034 13.9 1.8 0.034 13.8 0.4 1.8 1 1 0 1 1 1 0 Glycophorin A T2SF PF00482.18 EAU89632.1 - 0.036 13.9 0.3 0.036 13.9 0.2 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TMEM154 PF15102.1 EAU89632.1 - 0.19 11.4 3.8 0.7 9.5 2.6 2.0 1 1 0 1 1 1 0 TMEM154 protein family Mem_trans PF03547.13 EAU89632.1 - 0.48 8.6 6.1 0.39 8.9 3.6 1.3 1 1 0 1 1 1 0 Membrane transport protein DUF3753 PF12575.3 EAU89632.1 - 0.83 9.4 7.0 0.74 9.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) MpPF26 PF07666.6 EAU89632.1 - 1.4 8.8 7.1 3.5 7.5 5.0 1.6 1 1 0 1 1 1 0 M penetrans paralogue family 26 EphA2_TM PF14575.1 EAU89632.1 - 1.5 9.3 3.5 2.1 8.7 0.3 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Baculo_E56 PF04639.7 EAU89632.1 - 5.6 5.5 6.1 1.6 7.3 1.4 1.8 2 1 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope TPR_11 PF13414.1 EAU89633.1 - 0.058 13.0 0.0 7.6 6.2 0.0 3.4 3 0 0 3 3 3 0 TPR repeat SIS PF01380.17 EAU89635.1 - 1.1e-63 212.6 0.3 1.2e-32 112.2 0.1 2.6 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EAU89635.1 - 1.6e-23 82.9 0.2 8.9e-17 60.8 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EAU89635.1 - 4e-20 72.1 0.0 8.9e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EAU89635.1 - 6e-14 51.8 0.0 2e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EAU89635.1 - 1e-07 30.9 0.0 1.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EAU89635.1 - 0.0046 16.6 0.1 0.02 14.5 0.0 2.1 2 1 0 2 2 2 1 SIS domain DUF3270 PF11674.3 EAU89638.1 - 1.3 9.1 5.4 3.9 7.5 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) Alpha_kinase PF02816.13 EAU89640.1 - 7.6e-05 22.4 1.2 0.00011 21.9 0.2 1.6 2 0 0 2 2 2 1 Alpha-kinase family MraZ PF02381.13 EAU89640.1 - 0.089 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 MraZ protein ADH_zinc_N PF00107.21 EAU89641.1 - 1.1e-20 73.5 0.4 1.9e-20 72.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU89641.1 - 3.1e-09 36.5 0.1 5.7e-08 32.4 0.0 2.9 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EAU89641.1 - 0.0078 16.1 0.3 2 8.5 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal adh_short PF00106.20 EAU89641.1 - 0.029 14.2 0.3 0.046 13.6 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase PRC PF05239.11 EAU89641.1 - 0.083 12.7 0.1 0.28 11.0 0.1 1.9 1 0 0 1 1 1 0 PRC-barrel domain SIS_2 PF13580.1 EAU89641.1 - 0.15 11.7 1.5 14 5.4 0.0 2.3 2 0 0 2 2 2 0 SIS domain GFA PF04828.9 EAU89642.2 - 2.7e-19 68.8 7.4 1.1e-07 31.7 0.7 4.7 3 2 1 4 4 4 3 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.9 EAU89643.2 - 5.1e-06 26.3 0.3 5.1e-06 26.3 0.2 2.2 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EAU89643.2 - 0.2 11.5 2.8 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cu-oxidase PF00394.17 EAU89644.1 - 8.6e-48 162.2 0.0 3.1e-42 144.1 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU89644.1 - 6.9e-37 126.0 10.0 6e-35 119.7 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU89644.1 - 9.8e-35 118.8 1.3 1.9e-33 114.6 0.2 3.1 3 1 0 3 3 3 1 Multicopper oxidase Halogen_Hydrol PF10112.4 EAU89645.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein TFIIE_alpha PF02002.12 EAU89646.2 - 6.9e-19 67.2 0.4 1.3e-18 66.4 0.3 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit RecO_N_2 PF13114.1 EAU89646.2 - 0.0073 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 RecO N terminal Zn_Tnp_IS1595 PF12760.2 EAU89646.2 - 0.017 14.9 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EAU89646.2 - 0.1 11.9 0.2 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Glyco_hydro_10 PF00331.15 EAU89647.2 - 4.1e-85 285.6 0.1 5.1e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EAU89647.2 - 1.7e-13 49.9 13.5 4.6e-13 48.5 9.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF4339 PF14237.1 EAU89647.2 - 0.07 12.7 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) Glyco_hydro_10 PF00331.15 EAU89648.2 - 1.4e-81 274.0 0.1 1.1e-41 142.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EAU89648.2 - 0.0018 17.8 4.6 0.0043 16.6 3.2 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 EAU89649.2 - 4e-12 46.4 0.0 6.4e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAU89649.2 - 0.00032 20.8 0.6 0.00062 19.9 0.4 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Na_Ca_ex PF01699.19 EAU89650.2 - 1.1e-32 112.5 30.1 4e-19 68.6 4.7 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EAU89650.2 - 2.1 8.2 7.7 0.11 12.4 0.4 2.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Cys_Met_Meta_PP PF01053.15 EAU89651.1 - 1.2e-26 92.9 0.0 1.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EAU89651.1 - 0.0002 20.4 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tox-ODYAM1 PF15642.1 EAU89651.1 - 0.03 13.0 0.1 0.044 12.4 0.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus CBS PF00571.23 EAU89652.2 - 2.3e-13 49.6 0.4 0.0063 16.2 0.0 3.4 3 0 0 3 3 3 3 CBS domain Chordopox_A30L PF06015.7 EAU89652.2 - 0.092 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Lipase_3 PF01764.20 EAU89653.2 - 4.6e-21 74.9 0.0 8e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EAU89653.2 - 0.002 18.0 0.0 0.0046 16.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU89653.2 - 0.0052 16.5 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAU89653.2 - 0.0083 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Pox_A_type_inc PF04508.7 EAU89653.2 - 0.061 13.1 0.8 0.061 13.1 0.6 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Na_H_Exchanger PF00999.16 EAU89655.2 - 3.4e-31 108.1 32.0 2.1e-19 69.3 16.4 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Abhydrolase_6 PF12697.2 EAU89656.1 - 3.4e-29 102.3 0.4 5.5e-29 101.6 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU89656.1 - 4.6e-15 55.8 0.0 5.1e-14 52.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU89656.1 - 8.6e-14 51.5 0.0 4.1e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAU89656.1 - 0.00088 18.7 0.0 0.9 8.9 0.0 2.5 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Esterase PF00756.15 EAU89656.1 - 0.0011 18.4 0.0 0.002 17.6 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.9 EAU89656.1 - 0.0034 15.8 0.0 0.0047 15.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family DLH PF01738.13 EAU89656.1 - 0.0057 15.9 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EAU89656.1 - 0.065 12.9 0.0 0.8 9.3 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 EAU89656.1 - 0.066 13.4 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 EAU89656.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase RecA PF00154.16 EAU89657.2 - 3.1e-07 29.7 0.0 5.9e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EAU89657.2 - 6.3e-07 28.7 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KaiC Rad51 PF08423.6 EAU89657.2 - 0.00073 18.5 0.0 0.0035 16.2 0.0 1.9 1 1 0 1 1 1 1 Rad51 HHH_5 PF14520.1 EAU89657.2 - 0.0072 16.4 0.2 0.019 15.1 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain PAXNEB PF05625.6 EAU89657.2 - 0.018 13.8 1.0 0.041 12.7 0.1 1.8 2 0 0 2 2 2 0 PAXNEB protein AAA_19 PF13245.1 EAU89657.2 - 0.03 14.0 0.0 0.2 11.4 0.0 2.3 3 0 0 3 3 3 0 Part of AAA domain SAM_2 PF07647.12 EAU89657.2 - 0.091 12.6 0.1 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) CNH PF00780.17 EAU89658.2 - 0.0067 15.8 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 CNH domain RRM_1 PF00076.17 EAU89659.2 - 3e-23 81.2 0.0 7.5e-12 44.7 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU89659.2 - 6e-20 70.8 0.0 5.3e-10 38.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89659.2 - 6.9e-16 57.9 0.0 1.2e-08 34.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PIG-P PF08510.7 EAU89660.1 - 1.3e-32 112.0 5.0 1.6e-32 111.7 3.5 1.1 1 0 0 1 1 1 1 PIG-P XPG_I PF00867.13 EAU89661.2 - 7.5e-26 90.0 0.0 1.6e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAU89661.2 - 2e-24 85.7 0.0 4.7e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EAU89661.2 - 3.4e-06 26.7 0.0 7.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EAU89661.2 - 0.00028 21.0 0.0 0.00069 19.8 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.23 EAU89661.2 - 0.015 14.8 0.2 0.087 12.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU89661.2 - 0.016 15.1 0.3 0.042 13.7 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_5 PF14520.1 EAU89661.2 - 0.041 14.0 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain 5-FTHF_cyc-lig PF01812.15 EAU89663.2 - 1e-20 74.3 0.0 1.5e-20 73.7 0.0 1.3 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family zf-C2H2 PF00096.21 EAU89664.2 - 2.7e-10 39.9 6.8 4e-06 26.8 1.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU89664.2 - 4.6e-07 29.7 4.5 0.00046 20.3 0.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU89664.2 - 0.00019 21.4 0.8 0.00066 19.7 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU89664.2 - 0.00029 20.9 0.5 0.001 19.2 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EAU89664.2 - 0.00088 19.4 14.5 0.014 15.6 0.1 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EAU89664.2 - 0.018 14.9 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger ThiC-associated PF13667.1 EAU89664.2 - 0.11 12.0 0.1 0.32 10.5 0.1 1.7 1 0 0 1 1 1 0 ThiC-associated domain zf-BED PF02892.10 EAU89664.2 - 0.72 9.6 5.6 0.5 10.1 0.9 2.5 2 0 0 2 2 2 0 BED zinc finger Glyco_hydro_16 PF00722.16 EAU89665.1 - 9.1e-39 132.6 0.9 1.6e-38 131.8 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EAU89665.1 - 6.5 6.8 21.0 0.4 10.6 10.7 2.0 2 1 0 2 2 2 0 Chitin recognition protein Metallophos PF00149.23 EAU89666.2 - 8.4e-11 41.6 2.4 1.5e-10 40.8 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pro_CA PF00484.14 EAU89668.1 - 4.2e-35 121.0 0.1 3.7e-34 117.9 0.0 2.1 1 1 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.14 EAU89669.2 - 9.9e-34 116.5 0.0 1.4e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase CDC45 PF02724.9 EAU89670.2 - 4.9 5.0 12.2 6.9 4.5 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.2 EAU89673.2 - 2.2e-42 143.2 0.7 2.5e-10 40.5 0.0 5.8 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU89673.2 - 5.6e-36 122.2 7.0 2.5e-10 40.6 0.1 8.4 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.25 EAU89673.2 - 1.1e-30 103.9 12.2 0.002 17.8 0.0 11.0 12 0 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.1 EAU89673.2 - 3.8e-29 100.0 12.0 2.4e-09 37.1 0.2 7.6 5 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU89673.2 - 3.8e-27 91.6 1.5 0.0023 17.9 0.0 9.9 10 0 0 10 10 10 6 Ankyrin repeat NACHT PF05729.7 EAU89673.2 - 0.04 13.5 1.8 0.57 9.8 1.2 2.3 1 1 0 1 1 1 0 NACHT domain Ank_2 PF12796.2 EAU89674.2 - 6.1e-173 561.7 46.6 3.8e-17 62.3 0.0 15.9 3 2 17 20 20 20 19 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU89674.2 - 3.4e-134 435.1 24.2 2.3e-10 40.6 0.0 22.2 9 5 15 24 24 24 23 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU89674.2 - 4.1e-130 420.9 38.4 1.5e-11 44.0 0.1 24.0 8 7 17 25 25 25 23 Ankyrin repeats (many copies) Ank PF00023.25 EAU89674.2 - 1.5e-123 396.9 40.4 6.1e-08 32.0 0.1 29.6 30 1 0 30 30 30 23 Ankyrin repeat Ank_3 PF13606.1 EAU89674.2 - 2e-94 299.9 12.9 7.7e-05 22.5 0.0 28.6 29 0 0 29 29 29 16 Ankyrin repeat TRAP-delta PF05404.7 EAU89674.2 - 0.32 10.4 0.0 6.3 6.2 0.0 2.9 3 0 0 3 3 3 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) ERbeta_N PF12497.3 EAU89675.2 - 0.37 10.6 3.2 0.15 11.9 0.3 1.7 2 0 0 2 2 2 0 Estrogen receptor beta Ank_2 PF12796.2 EAU89676.2 - 6.6e-76 250.7 6.7 4.2e-15 55.8 0.0 9.7 3 2 5 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU89676.2 - 6.2e-63 208.1 12.5 8.2e-08 32.5 0.0 13.6 11 2 3 14 14 14 10 Ankyrin repeats (many copies) Ank PF00023.25 EAU89676.2 - 3.4e-60 196.9 12.7 0.00038 20.1 0.0 16.3 16 0 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.1 EAU89676.2 - 1.3e-55 184.1 16.4 1.7e-07 31.2 0.0 12.4 8 4 4 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU89676.2 - 7.9e-35 115.4 7.6 0.015 15.4 0.0 16.1 16 1 0 16 16 16 7 Ankyrin repeat NACHT PF05729.7 EAU89676.2 - 7.5e-08 32.2 0.1 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU89676.2 - 3.6e-07 30.3 0.0 1.3e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU89676.2 - 1.2e-05 25.3 0.8 4.5e-05 23.4 0.5 2.0 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EAU89676.2 - 1.6e-05 23.8 0.0 2.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF2002 PF09400.5 EAU89676.2 - 0.027 14.1 0.0 0.32 10.7 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2002) Ank_4 PF13637.1 EAU89677.1 - 7.6e-53 176.0 15.8 5.1e-10 39.6 0.1 8.7 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU89677.1 - 2.1e-50 167.5 24.3 1.4e-08 34.7 0.0 8.6 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU89677.1 - 2.2e-50 168.9 8.0 3.8e-16 59.1 0.4 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EAU89677.1 - 3.7e-49 162.1 10.7 6.1e-06 25.7 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.1 EAU89677.1 - 1.8e-34 114.3 5.3 0.00084 19.3 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Peptidase_M16 PF00675.15 EAU89677.1 - 0.041 13.6 0.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) ROK PF00480.15 EAU89677.1 - 0.11 12.3 0.1 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 ROK family EphA2_TM PF14575.1 EAU89678.1 - 0.00063 20.0 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.5 EAU89678.1 - 0.0031 16.8 1.9 0.0059 15.9 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EAU89678.1 - 0.023 14.2 0.3 0.041 13.4 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PDGLE PF13190.1 EAU89678.1 - 0.11 12.2 0.8 0.27 10.9 0.5 1.7 1 0 0 1 1 1 0 PDGLE domain DUF1191 PF06697.7 EAU89678.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Syndecan PF01034.15 EAU89678.1 - 0.37 10.4 2.6 0.7 9.5 1.8 1.4 1 0 0 1 1 1 0 Syndecan domain Beta-APP PF03494.8 EAU89678.1 - 4.6 6.7 8.1 8.7 5.9 5.6 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Ank_2 PF12796.2 EAU89679.2 - 4.4e-55 183.9 16.0 4.8e-11 42.8 0.2 8.8 1 1 7 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU89679.2 - 4e-50 167.3 10.9 1.4e-09 38.1 0.0 10.7 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU89679.2 - 4.5e-48 160.1 11.6 2.4e-11 43.4 0.1 9.7 4 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.25 EAU89679.2 - 3.6e-43 143.2 1.5 2.4e-05 23.8 0.0 13.5 11 2 1 12 12 12 10 Ankyrin repeat Ank_3 PF13606.1 EAU89679.2 - 1.6e-35 117.5 3.0 0.00079 19.4 0.0 13.4 14 1 1 15 15 15 7 Ankyrin repeat ABC2_membrane PF01061.19 EAU89680.2 - 8.8e-81 270.0 48.4 3.3e-42 144.0 15.0 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EAU89680.2 - 9e-39 132.9 0.0 7.3e-18 65.1 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EAU89680.2 - 2.7e-37 126.5 6.6 1.2e-28 98.7 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EAU89680.2 - 1.9e-18 66.2 0.0 7.5e-18 64.3 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EAU89680.2 - 2.1e-08 33.6 12.3 2.1e-08 33.6 8.5 3.4 2 1 0 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EAU89680.2 - 4e-08 32.9 0.0 0.00091 18.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EAU89680.2 - 4.1e-06 26.9 0.0 0.053 13.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAU89680.2 - 5.8e-06 25.5 0.0 0.00026 20.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EAU89680.2 - 4.8e-05 23.4 0.0 0.017 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EAU89680.2 - 0.00033 20.9 0.0 0.048 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EAU89680.2 - 0.00036 20.0 0.0 0.032 13.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EAU89680.2 - 0.00059 19.8 0.2 1.3 8.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAU89680.2 - 0.0011 18.4 0.8 0.056 12.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 EAU89680.2 - 0.0014 18.2 0.4 0.34 10.5 0.1 2.9 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EAU89680.2 - 0.0031 17.3 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EAU89680.2 - 0.0038 18.0 0.0 0.5 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAU89680.2 - 0.0044 16.6 0.0 0.24 11.0 0.0 2.7 3 0 0 3 3 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 EAU89680.2 - 0.0045 16.4 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EAU89680.2 - 0.0055 16.4 0.3 0.52 10.0 0.2 2.7 2 0 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 EAU89680.2 - 0.007 15.6 0.0 0.23 10.6 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EAU89680.2 - 0.007 15.8 0.2 3.3 7.0 0.3 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_21 PF13304.1 EAU89680.2 - 0.0076 16.2 0.0 1 9.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EAU89680.2 - 0.01 16.3 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EAU89680.2 - 0.019 14.9 0.0 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EAU89680.2 - 0.042 13.7 0.0 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4059 PF13268.1 EAU89680.2 - 0.046 13.8 0.1 0.046 13.8 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF4059) AAA_30 PF13604.1 EAU89680.2 - 0.083 12.4 0.2 3.7 7.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.4 EAU89680.2 - 0.099 11.2 0.3 0.74 8.3 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RNA_helicase PF00910.17 EAU89680.2 - 0.11 12.6 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Septin PF00735.13 EAU89680.2 - 0.14 11.0 0.0 7.3 5.5 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_23 PF13476.1 EAU89680.2 - 0.31 11.3 0.1 0.63 10.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EAU89680.2 - 0.68 8.5 0.0 7.4 5.1 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF4436 PF14494.1 EAU89682.2 - 2.3e-05 23.8 1.6 4.4e-05 22.9 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) SMC_N PF02463.14 EAU89683.1 - 5.9e-63 212.0 0.0 2.2e-62 210.1 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EAU89683.1 - 2.3e-30 104.9 0.1 9e-30 103.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EAU89683.1 - 1.4e-12 48.2 1.7 1e-06 28.9 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAU89683.1 - 2.9e-07 29.9 0.0 6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EAU89683.1 - 1.3e-05 24.5 28.5 0.031 13.4 1.6 4.9 3 1 2 5 5 5 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 EAU89683.1 - 0.00068 19.5 0.0 0.0035 17.2 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ADIP PF11559.3 EAU89683.1 - 0.0015 18.4 2.3 0.0015 18.4 1.6 7.8 4 1 4 8 8 8 2 Afadin- and alpha -actinin-Binding Sec8_exocyst PF04048.9 EAU89683.1 - 0.0024 17.5 4.1 0.0024 17.5 2.8 5.9 5 1 1 6 6 6 2 Sec8 exocyst complex component specific domain WEMBL PF05701.6 EAU89683.1 - 0.0055 15.2 0.5 0.0055 15.2 0.4 5.8 3 2 2 5 5 5 2 Weak chloroplast movement under blue light CENP-F_leu_zip PF10473.4 EAU89683.1 - 0.0071 16.1 4.7 0.0071 16.1 3.2 7.7 4 2 2 7 7 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EAU89683.1 - 0.0072 16.0 8.8 0.0072 16.0 6.1 7.5 3 1 4 7 7 6 2 TPR/MLP1/MLP2-like protein ABC_tran PF00005.22 EAU89683.1 - 0.078 13.2 0.0 0.078 13.2 0.0 5.7 5 2 0 5 5 4 0 ABC transporter Peptidase_C10 PF01640.12 EAU89683.1 - 0.17 11.6 2.5 0.3 10.8 0.0 2.5 2 1 0 2 2 2 0 Peptidase C10 family DUF1664 PF07889.7 EAU89683.1 - 3.4 7.4 50.6 0.49 10.1 1.0 6.8 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) MtrG PF04210.8 EAU89683.1 - 5.3 6.7 12.2 9.2 6.0 0.0 5.4 4 2 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase, subunit G Aldo_ket_red PF00248.16 EAU89685.2 - 3.7e-52 176.9 0.0 4.3e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_binding_2 PF13380.1 EAU89685.2 - 0.048 13.8 0.2 30 4.8 0.0 3.2 2 1 1 3 3 3 0 CoA binding domain DUF706 PF05153.10 EAU89686.1 - 2.3e-130 433.4 1.2 2.7e-130 433.1 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EAU89686.1 - 0.0056 16.6 0.0 0.035 14.1 0.0 2.1 2 0 0 2 2 2 1 HD domain HAD PF12710.2 EAU89687.1 - 5.2e-13 49.5 0.0 7.6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAU89687.1 - 3.8e-07 30.4 0.0 9e-06 26.0 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EAU89687.1 - 0.00059 19.0 0.0 0.0021 17.2 0.0 1.8 2 0 0 2 2 2 1 Putative Phosphatase Hydrolase PF00702.21 EAU89687.1 - 0.0011 19.4 0.3 0.066 13.6 0.0 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EAU89687.1 - 0.009 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Lactamase_B_2 PF12706.2 EAU89687.1 - 0.081 12.4 0.1 0.16 11.4 0.0 1.6 2 1 0 2 2 2 0 Beta-lactamase superfamily domain DUF3954 PF13128.1 EAU89687.1 - 0.099 12.0 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) Vps39_2 PF10367.4 EAU89689.1 - 2.6e-11 43.6 0.1 1.2e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EAU89689.1 - 1.1e-08 35.0 1.2 1.9e-06 27.8 0.0 3.6 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 EAU89689.1 - 7.8e-05 22.2 0.3 0.06 12.9 0.0 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS Cnd1 PF12717.2 EAU89690.2 - 8.1e-58 195.1 12.4 1.9e-55 187.4 0.1 4.6 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EAU89690.2 - 8e-51 172.0 0.0 8e-51 172.0 0.0 4.8 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EAU89690.2 - 4.1e-10 39.7 0.5 0.011 16.0 0.2 5.3 6 1 0 6 6 6 2 HEAT repeats HEAT PF02985.17 EAU89690.2 - 0.00011 22.0 4.9 4.3 7.6 0.1 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EAU89690.2 - 0.0006 20.2 1.2 3.6 8.1 0.0 4.7 5 0 0 5 5 5 2 HEAT-like repeat Ribosomal_S6e PF01092.14 EAU89691.1 - 5.4e-61 203.8 0.1 8.4e-61 203.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e PGC7_Stella PF15549.1 EAU89691.1 - 0.46 10.4 4.3 0.73 9.7 3.0 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Ribosomal_S13_N PF08069.7 EAU89692.1 - 1.8e-30 104.5 0.1 4e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EAU89692.1 - 6.3e-22 77.1 0.0 9.9e-22 76.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EAU89692.1 - 0.0082 15.8 0.0 0.015 14.9 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain DUF4462 PF14692.1 EAU89693.2 - 0.073 12.3 0.1 0.16 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) DNA_pol_A_exo1 PF01612.15 EAU89694.2 - 0.036 13.5 0.0 1.1 8.6 0.0 2.3 1 1 0 2 2 2 0 3'-5' exonuclease PIP5K PF01504.13 EAU89695.2 - 1.6e-86 289.5 0.1 2.3e-86 289.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sua5_yciO_yrdC PF01300.13 EAU89695.2 - 0.007 15.6 0.1 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination Ank_2 PF12796.2 EAU89696.2 - 1.9e-66 220.4 8.8 5.9e-14 52.1 0.0 7.8 1 1 8 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EAU89696.2 - 4.1e-56 184.1 8.3 5.2e-06 26.0 0.0 13.4 13 0 0 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 EAU89696.2 - 1.2e-49 165.8 4.1 2.2e-12 47.1 0.0 7.9 4 2 2 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU89696.2 - 3.9e-45 150.8 16.3 3.4e-12 46.1 0.0 10.6 3 2 7 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU89696.2 - 9.6e-41 133.7 5.0 0.0055 16.8 0.0 13.5 13 0 0 13 13 13 8 Ankyrin repeat NACHT PF05729.7 EAU89696.2 - 1.7e-07 31.0 0.1 4.9e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EAU89696.2 - 0.0003 20.9 0.0 0.0024 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAU89696.2 - 0.0018 17.1 0.0 0.008 15.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 EAU89696.2 - 0.0019 18.1 0.0 0.0097 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EAU89696.2 - 0.022 14.5 0.0 0.42 10.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EAU89696.2 - 0.027 14.6 0.0 0.44 10.7 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAU89696.2 - 0.035 13.1 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EAU89696.2 - 0.07 12.6 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EAU89696.2 - 0.076 13.3 0.0 1.2 9.4 0.0 2.9 2 1 0 2 2 2 0 ABC transporter Pkinase PF00069.20 EAU89700.2 - 3.5e-05 23.0 0.0 7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain rve PF00665.21 EAU89702.2 - 0.00016 21.7 0.0 0.0004 20.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Alpha_kinase PF02816.13 EAU89703.2 - 1.9e-18 66.8 0.0 5.4e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 Alpha-kinase family MAM33 PF02330.11 EAU89704.2 - 3.3e-38 131.5 0.6 4.2e-38 131.1 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein HHH_2 PF12826.2 EAU89704.2 - 0.1 12.4 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.17 EAU89705.2 - 7.2e-50 166.5 0.0 7.3e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU89705.2 - 5.3e-33 112.8 0.0 1.1e-10 41.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU89705.2 - 4.2e-20 71.3 0.0 2.3e-05 24.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EAU89705.2 - 0.00016 21.3 0.0 0.0033 17.1 0.0 2.9 3 0 0 3 3 3 1 Limkain b1 DUF3343 PF11823.3 EAU89705.2 - 0.0031 16.7 0.7 0.017 14.3 0.0 2.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3343) RRM_3 PF08777.6 EAU89705.2 - 0.0073 16.1 0.0 13 5.7 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif MIP-T3 PF10243.4 EAU89705.2 - 8.7 4.6 21.6 12 4.2 14.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pkinase PF00069.20 EAU89706.2 - 2.7e-06 26.7 0.0 7.9e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.20 EAU89707.2 - 9.6e-05 21.6 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU89707.2 - 0.057 13.1 0.1 0.23 11.1 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EAU89709.2 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89710.2 - 6.1e-07 28.8 0.0 0.00029 20.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase PF00069.20 EAU89711.2 - 9.3e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89712.2 - 2.6e-71 239.8 0.0 4e-71 239.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89712.2 - 3.6e-44 150.8 0.0 5.5e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EAU89712.2 - 3.7e-12 46.0 0.3 3e-08 33.5 0.1 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EAU89712.2 - 4.5e-10 38.9 0.1 3e-09 36.2 0.0 2.3 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EAU89712.2 - 0.007 15.4 0.0 0.11 11.5 0.0 2.5 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU89712.2 - 0.052 13.2 0.3 0.68 9.6 0.1 2.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ebola_NP PF05505.7 EAU89712.2 - 0.24 9.4 7.5 0.097 10.7 3.4 1.5 2 0 0 2 2 2 0 Ebola nucleoprotein Pkinase PF00069.20 EAU89716.2 - 3.9e-06 26.2 0.0 7.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89720.2 - 9.5e-07 28.2 0.0 1.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EAU89720.2 - 0.21 10.8 0.0 0.67 9.2 0.0 1.7 2 0 0 2 2 2 0 RIO1 family 5_nucleotid PF05761.9 EAU89720.2 - 0.25 9.8 0.0 0.39 9.1 0.0 1.2 1 0 0 1 1 1 0 5' nucleotidase family Pkinase PF00069.20 EAU89722.2 - 5.6e-06 25.6 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89722.2 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DEAD PF00270.24 EAU89723.2 - 7.6e-24 84.0 0.0 1.7e-20 73.2 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase RQC PF09382.5 EAU89723.2 - 3e-12 46.2 0.0 1.5e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.26 EAU89723.2 - 9e-08 31.8 0.0 2.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF768 PF05589.6 EAU89723.2 - 0.096 12.6 0.1 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Filo_glycop PF01611.11 EAU89724.2 - 0.091 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein E1-E2_ATPase PF00122.15 EAU89725.1 - 8.8e-66 221.2 6.1 1.7e-65 220.3 4.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAU89725.1 - 8.1e-35 119.9 4.9 8.1e-35 119.9 3.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAU89725.1 - 4.5e-27 95.8 0.5 3.3e-21 76.6 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAU89725.1 - 1.4e-15 56.4 0.0 3.9e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EAU89725.1 - 2.9e-14 52.8 0.0 5.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAU89725.1 - 1.7e-12 47.8 0.0 3.8e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAU89725.1 - 0.00099 18.7 0.7 0.0079 15.7 0.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EAU89727.1 - 0.004 16.3 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89727.1 - 0.044 12.8 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU89728.1 - 1.7e-06 27.4 0.0 2.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89728.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3666 PF12408.3 EAU89728.1 - 0.18 10.9 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase PapG_N PF03627.8 EAU89728.1 - 0.21 11.0 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain BTB PF00651.26 EAU89731.2 - 0.0031 17.4 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DZR PF12773.2 EAU89731.2 - 0.31 10.8 9.7 1.7 8.5 1.0 2.0 1 1 1 2 2 2 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.14 EAU89731.2 - 1.5 8.9 5.0 7.6 6.6 0.4 2.4 2 0 0 2 2 2 0 DnaJ central domain APH PF01636.18 EAU89737.2 - 1.5e-14 54.2 0.2 1.1e-12 48.2 0.0 2.7 3 1 0 3 3 3 2 Phosphotransferase enzyme family DUF1679 PF07914.6 EAU89737.2 - 0.012 14.2 0.0 2.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Fimbrial_K88 PF02432.10 EAU89740.2 - 0.062 12.7 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Peptidase_C14 PF00656.17 EAU89742.2 - 1.8e-22 80.2 0.0 4e-22 79.1 0.0 1.6 1 1 0 1 1 1 1 Caspase domain HMG_box PF00505.14 EAU89745.1 - 6.8e-14 51.8 0.2 1.5e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU89745.1 - 4.3e-05 23.7 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain Peptidase_C2 PF00648.16 EAU89746.2 - 2.8e-46 157.8 3.5 9.6e-33 113.4 1.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Peptidase_C2 PF00648.16 EAU89747.1 - 7.1e-50 169.6 4.1 1.2e-35 122.9 0.9 2.2 1 1 0 2 2 2 2 Calpain family cysteine protease Peptidase_C2 PF00648.16 EAU89751.2 - 1.5e-54 185.0 0.2 1.4e-38 132.5 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease WD40 PF00400.27 EAU89752.2 - 2e-18 65.5 7.9 2.6e-07 30.2 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat SnoaL PF07366.7 EAU89753.1 - 0.011 15.3 0.4 1.9 8.0 0.0 2.4 2 1 1 3 3 3 0 SnoaL-like polyketide cyclase ACC_epsilon PF13822.1 EAU89753.1 - 1.3 9.3 7.0 7.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Glyco_hydro_61 PF03443.9 EAU89754.1 - 1.9e-44 152.1 0.0 2.3e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EAU89755.2 - 2.2e-38 132.2 0.0 2.9e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HECT_2 PF09814.4 EAU89756.2 - 9.6e-40 136.3 0.0 1.4e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding FUSC PF04632.7 EAU89756.2 - 4.4 5.6 5.9 0.85 7.9 0.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Cutinase PF01083.17 EAU89757.1 - 8.2e-38 129.9 0.0 9.6e-38 129.6 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EAU89757.1 - 7.6e-05 22.3 0.0 0.00012 21.7 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EAU89757.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.15 EAU89757.1 - 0.006 16.8 0.0 0.0075 16.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_9 PF10081.4 EAU89757.1 - 0.0067 15.1 0.0 0.0089 14.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family VirJ PF06057.6 EAU89757.1 - 0.0068 16.2 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 EAU89757.1 - 0.0092 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EAU89757.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU89757.1 - 0.064 13.1 0.0 0.081 12.7 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase PF00151.14 EAU89757.1 - 0.085 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipase Mid2 PF04478.7 EAU89759.2 - 0.06 12.7 0.6 0.11 11.8 0.4 1.5 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor PPTA PF01239.17 EAU89761.2 - 4.5e-42 139.6 12.4 4.9e-09 35.1 0.0 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 EAU89761.2 - 0.016 15.8 0.6 2 9.2 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EAU89761.2 - 0.032 14.4 0.7 1 9.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_20 PF00982.16 EAU89762.2 - 1.3e-145 485.5 0.2 3.5e-145 484.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EAU89762.2 - 4.4e-74 248.3 0.0 2.2e-73 246.0 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_6 PF13344.1 EAU89762.2 - 0.048 13.5 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MtaB PF12176.3 EAU89768.1 - 0.16 10.3 0.0 0.25 9.7 0.0 1.3 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Pkinase PF00069.20 EAU89776.1 - 7.7e-06 25.2 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89776.1 - 0.029 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase PhoPQ_related PF10142.4 EAU89778.2 - 7.4e-13 47.7 13.8 0.21 10.0 0.0 7.9 8 0 0 8 8 8 5 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 EAU89778.2 - 2e-08 33.1 31.9 0.56 8.6 0.1 8.2 8 0 0 8 8 8 7 Acetyl xylan esterase (AXE1) Motilin_assoc PF04643.7 EAU89778.2 - 7.9e-08 31.6 0.0 16 5.0 0.0 8.3 9 0 0 9 9 9 0 Motilin/ghrelin-associated peptide Bmp PF02608.9 EAU89778.2 - 2.8e-07 29.6 10.9 7 5.2 0.0 8.2 9 0 0 9 9 9 1 Basic membrane protein DUF463 PF04317.7 EAU89778.2 - 0.0003 19.4 14.4 20 3.6 0.0 7.6 8 0 0 8 8 8 0 YcjX-like family, DUF463 Pepsin-I3 PF06394.8 EAU89778.2 - 0.00082 18.9 17.6 33 4.2 0.0 7.7 8 0 0 8 8 7 0 Pepsin inhibitor-3-like repeated domain UPF0004 PF00919.15 EAU89778.2 - 0.0012 18.6 5.5 70 3.3 0.0 7.5 8 0 0 8 8 8 0 Uncharacterized protein family UPF0004 DUF1687 PF07955.6 EAU89778.2 - 0.0054 16.6 12.9 23 4.9 0.1 7.0 8 0 0 8 8 8 0 Protein of unknown function (DUF1687) AAA_22 PF13401.1 EAU89778.2 - 0.034 14.2 0.0 15 5.6 0.0 5.1 6 0 0 6 6 5 0 AAA domain COQ9 PF08511.6 EAU89778.2 - 0.16 11.5 0.0 87 2.7 0.0 4.4 5 0 0 5 5 5 0 COQ9 ITAM PF02189.10 EAU89778.2 - 0.17 12.2 3.6 5.4e+02 1.2 0.0 5.6 6 0 0 6 6 6 0 Immunoreceptor tyrosine-based activation motif DUF1451 PF07295.6 EAU89778.2 - 1.4 8.6 0.0 4.4e+02 0.5 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1451) SCHIP-1 PF10148.4 EAU89778.2 - 1.8 7.8 2.2 5.5e+02 -0.3 0.0 4.9 8 0 0 8 8 8 0 Schwannomin-interacting protein 1 Inhibitor_I48 PF10467.4 EAU89778.2 - 2.4 8.0 10.8 92 2.9 0.0 6.2 8 0 0 8 8 8 0 Peptidase inhibitor clitocypin DUF2758 PF10957.3 EAU89778.2 - 3 7.7 0.2 6.5e+02 0.2 0.0 4.3 7 0 0 7 7 6 0 Protein of unknown function (DUF2758) DUF2048 PF09752.4 EAU89778.2 - 8.5 5.1 28.3 19 3.9 0.8 7.2 7 0 0 7 7 7 0 Uncharacterized conserved protein (DUF2048) Pkinase PF00069.20 EAU89780.2 - 4.6e-10 39.0 0.0 8.4e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89780.2 - 0.00056 19.0 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU89781.2 - 4.7e-08 32.5 0.0 1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89781.2 - 0.072 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EAU89782.2 - 3e-07 29.8 0.0 5.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cutinase PF01083.17 EAU89783.1 - 4.4e-38 130.7 0.0 5.1e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EAU89783.1 - 5.7e-06 26.0 0.0 6.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EAU89783.1 - 0.00025 20.5 0.1 0.00036 19.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_9 PF10081.4 EAU89783.1 - 0.00026 19.7 0.0 0.00032 19.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family PE-PPE PF08237.6 EAU89783.1 - 0.0012 18.2 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EAU89783.1 - 0.0039 16.9 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EAU89783.1 - 0.006 16.0 0.0 0.0081 15.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase VirJ PF06057.6 EAU89783.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Thioesterase PF00975.15 EAU89783.1 - 0.021 15.0 0.0 0.028 14.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.2 EAU89783.1 - 0.033 14.0 0.0 0.039 13.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU89783.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Transferase PF02458.10 EAU89784.1 - 0.054 11.9 0.0 11 4.2 0.0 2.8 3 0 0 3 3 3 0 Transferase family Pkinase PF00069.20 EAU89786.2 - 1.4e-09 37.4 0.0 2.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89792.2 - 2.2e-06 27.0 0.0 4.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89792.2 - 0.071 12.1 0.0 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 EAU89793.1 - 3.2e-07 29.7 0.0 6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EAU89794.2 - 6.3e-22 76.5 15.4 3.9e-08 32.8 0.4 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAU89794.2 - 0.29 9.8 3.0 0.68 8.6 0.6 2.3 2 1 0 2 2 2 0 Nup133 N terminal like DUF605 PF04652.11 EAU89797.2 - 1 8.7 13.7 1.3 8.3 9.5 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EAU89800.1 - 1e-07 31.3 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PIF1 PF05970.9 EAU89804.2 - 1.7e-29 102.9 0.3 4.6e-29 101.4 0.1 1.8 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EAU89804.2 - 2.9e-11 43.2 2.8 1.1e-10 41.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 EAU89804.2 - 1.3e-05 24.8 0.0 3.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EAU89804.2 - 0.00088 18.9 11.7 0.031 13.8 0.0 4.3 3 2 0 4 4 4 2 AAA domain TrwB_AAD_bind PF10412.4 EAU89804.2 - 0.0039 15.8 0.1 0.0039 15.8 0.1 1.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 EAU89804.2 - 0.0082 16.3 0.1 0.037 14.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EAU89804.2 - 0.013 15.3 4.9 0.021 14.6 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ArgK PF03308.11 EAU89804.2 - 0.021 13.6 1.3 0.049 12.4 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AT_hook PF02178.14 EAU89805.2 - 2.1 8.2 8.3 7.5 6.5 5.7 2.0 1 0 0 1 1 1 0 AT hook motif WD40 PF00400.27 EAU89806.1 - 1e-22 79.1 14.4 3.4e-08 33.0 0.4 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EAU89806.1 - 0.15 10.8 2.3 1.5 7.5 0.2 2.4 2 1 1 3 3 3 0 Nup133 N terminal like Pkinase PF00069.20 EAU89807.2 - 1.1e-09 37.8 0.0 1.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89807.2 - 0.22 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Tet_JBP PF12851.2 EAU89813.2 - 1.4e-12 47.2 0.0 2.3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Imm35 PF15581.1 EAU89816.2 - 0.019 14.9 1.9 0.046 13.7 0.0 2.4 3 0 0 3 3 3 0 Immunity protein 35 GAT PF03127.9 EAU89817.2 - 0.043 13.7 1.1 0.081 12.9 0.2 1.9 2 0 0 2 2 2 0 GAT domain Tic22 PF04278.7 EAU89817.2 - 0.047 12.9 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Tic22-like family FANCI_S1-cap PF14674.1 EAU89817.2 - 0.14 12.2 1.6 9.2 6.4 0.1 2.6 2 0 0 2 2 2 0 FANCI solenoid 1 cap DUF948 PF06103.6 EAU89818.2 - 0.00035 20.3 1.9 0.076 12.8 0.2 2.4 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EAU89818.2 - 0.00074 19.8 4.2 0.00075 19.8 0.6 2.7 2 0 0 2 2 2 1 SlyX Microtub_assoc PF07989.6 EAU89818.2 - 0.011 15.5 0.3 0.011 15.5 0.2 2.0 2 0 0 2 2 2 0 Microtubule associated TMF_DNA_bd PF12329.3 EAU89818.2 - 0.017 14.9 1.3 0.017 14.9 0.9 2.9 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EAU89818.2 - 0.022 14.2 0.6 0.022 14.2 0.4 2.0 2 0 0 2 2 2 0 Septum formation initiator BCAS2 PF05700.6 EAU89818.2 - 0.037 13.4 3.3 0.081 12.3 2.3 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF837 PF05769.6 EAU89818.2 - 0.039 13.4 5.2 0.063 12.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF837) MbeD_MobD PF04899.7 EAU89818.2 - 0.047 13.6 0.3 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 MbeD/MobD like Spectrin PF00435.16 EAU89818.2 - 0.09 13.0 2.2 0.27 11.5 1.5 1.9 1 1 0 1 1 1 0 Spectrin repeat bZIP_1 PF00170.16 EAU89818.2 - 0.095 12.6 0.2 0.095 12.6 0.1 2.0 2 0 0 2 2 2 0 bZIP transcription factor PMEI PF04043.10 EAU89818.2 - 0.19 11.6 1.6 0.39 10.5 1.1 1.5 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Pkinase PF00069.20 EAU89819.2 - 1.5e-07 30.8 0.0 2.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89820.2 - 0.00026 20.2 0.0 0.0006 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Tet_JBP PF12851.2 EAU89821.2 - 3.3e-12 46.0 0.0 6.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Pkinase PF00069.20 EAU89821.2 - 9.5e-06 24.9 0.0 3.4e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Acetyltransf_13 PF13880.1 EAU89821.2 - 0.055 13.2 0.2 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase GTF2I PF02946.9 EAU89823.1 - 0.038 13.8 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 GTF2I-like repeat HMG_box_2 PF09011.5 EAU89823.1 - 0.056 13.8 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 HMG-box domain Nop14 PF04147.7 EAU89823.1 - 0.15 9.9 6.9 0.21 9.4 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EAU89823.1 - 0.64 7.9 6.3 0.89 7.5 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Tropomyosin_1 PF12718.2 EAU89824.1 - 1.1e-06 28.5 9.7 5.3e-05 23.1 2.1 3.4 1 1 2 3 3 3 2 Tropomyosin like Tropomyosin PF00261.15 EAU89824.1 - 8.1e-05 21.8 14.9 0.00053 19.1 10.3 2.4 1 1 0 1 1 1 1 Tropomyosin DUF2450 PF10475.4 EAU89824.1 - 0.0031 16.4 0.9 0.0054 15.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Spectrin PF00435.16 EAU89824.1 - 0.0047 17.1 5.0 0.24 11.7 0.5 3.3 1 1 3 4 4 4 2 Spectrin repeat DUF3584 PF12128.3 EAU89824.1 - 0.012 13.0 8.2 0.017 12.5 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Gasdermin PF04598.7 EAU89824.1 - 0.027 13.2 0.4 0.041 12.6 0.3 1.2 1 0 0 1 1 1 0 Gasdermin family AAA_13 PF13166.1 EAU89824.1 - 0.11 10.8 3.1 0.51 8.7 2.3 1.7 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EAU89824.1 - 0.17 11.0 1.3 0.55 9.3 0.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 EAU89824.1 - 0.29 10.5 9.6 1.9 7.8 6.7 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.7 EAU89824.1 - 0.33 10.6 5.6 0.33 10.6 0.5 3.1 2 1 2 4 4 4 0 Laminin Domain II Vac_Fusion PF02346.11 EAU89824.1 - 1.1 8.6 4.8 0.8 9.1 0.3 3.0 3 1 1 4 4 3 0 Chordopoxvirus fusion protein IncA PF04156.9 EAU89824.1 - 1.7 8.1 10.1 1.1 8.7 1.3 2.3 1 1 1 2 2 2 0 IncA protein DUF3422 PF11902.3 EAU89824.1 - 2.3 7.0 9.2 17 4.0 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) MCPsignal PF00015.16 EAU89824.1 - 2.5 7.5 9.3 6.5 6.2 2.2 2.8 2 1 1 3 3 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NOA36 PF06524.7 EAU89824.1 - 3 7.0 11.5 2.5 7.2 2.6 2.2 2 0 0 2 2 2 0 NOA36 protein DUF4164 PF13747.1 EAU89824.1 - 3 8.0 13.9 1.3 9.1 1.8 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 EAU89824.1 - 8.4 4.1 4.9 6 4.5 0.2 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family zf-C4pol PF14260.1 EAU89824.1 - 9 6.3 6.5 33 4.5 0.0 3.8 3 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF4414 PF14377.1 EAU89825.2 - 0.023 14.5 0.1 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Vac_Fusion PF02346.11 EAU89825.2 - 0.09 12.2 0.2 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein PTP_N PF12453.3 EAU89828.1 - 0.0032 17.0 0.9 0.0032 17.0 0.6 3.4 4 1 1 5 5 5 1 Protein tyrosine phosphatase N terminal SNF2_N PF00176.18 EAU89829.2 - 1.8e-73 246.9 0.0 2.9e-73 246.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EAU89829.2 - 7.2e-40 135.3 1.5 7.2e-40 135.3 1.0 2.5 3 0 0 3 3 2 1 SLIDE HAND PF09110.6 EAU89829.2 - 2.8e-27 95.3 0.8 2.8e-27 95.3 0.5 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EAU89829.2 - 7.1e-15 54.6 0.0 2.1e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU89829.2 - 4.2e-08 33.2 2.5 8.5e-08 32.2 0.0 3.0 3 2 1 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EAU89829.2 - 2.4e-07 29.9 0.0 2.4e-07 29.9 0.0 1.8 2 0 0 2 2 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EAU89829.2 - 7.3e-06 25.5 0.2 4.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBINO PF13892.1 EAU89829.2 - 2e-05 24.6 4.3 2e-05 24.6 3.0 3.4 3 0 0 3 3 3 1 DNA-binding domain AAA_14 PF13173.1 EAU89829.2 - 0.0065 16.3 0.2 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAU89829.2 - 0.031 13.6 0.9 3.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain DEAD_2 PF06733.10 EAU89829.2 - 0.062 12.7 0.1 0.16 11.3 0.1 1.7 1 0 0 1 1 1 0 DEAD_2 PBP PF01161.15 EAU89834.1 - 5.6e-09 36.0 0.1 6.9e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_92 PF07971.7 EAU89835.2 - 6.6e-120 401.0 0.0 1.8e-83 280.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 RicinB_lectin_2 PF14200.1 EAU89837.2 - 2.4e-15 56.7 0.1 1.4e-13 51.1 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EAU89837.2 - 0.016 15.2 0.0 0.75 9.8 0.0 2.2 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain adh_short PF00106.20 EAU89838.1 - 7.7e-08 32.4 0.1 1.5e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU89838.1 - 3.9e-05 23.3 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Pkinase PF00069.20 EAU89839.1 - 8.7e-09 34.9 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TauD PF02668.11 EAU89841.2 - 5.3e-17 62.3 0.0 1.3e-16 61.0 0.0 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HMG_box PF00505.14 EAU89842.1 - 5.4e-10 39.4 9.1 3.5e-09 36.7 6.3 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU89842.1 - 6.6e-08 32.8 4.0 1.8e-07 31.3 2.7 1.7 1 0 0 1 1 1 1 HMG-box domain MLANA PF14991.1 EAU89842.1 - 2.9 7.9 6.0 0.7 9.9 0.5 2.4 2 0 0 2 2 2 0 Protein melan-A Pkinase PF00069.20 EAU89843.2 - 0.00082 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89845.2 - 1.6e-05 24.1 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU89845.2 - 0.054 13.2 0.1 7.3 6.2 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF4413 PF14372.1 EAU89851.2 - 0.023 14.6 0.1 0.09 12.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) zf-CCHC PF00098.18 EAU89852.2 - 0.02 14.7 2.6 0.02 14.7 1.8 2.8 1 1 2 3 3 3 0 Zinc knuckle Zn_Tnp_IS1595 PF12760.2 EAU89852.2 - 0.098 12.4 8.9 0.16 11.8 6.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CCHC_6 PF15288.1 EAU89852.2 - 0.11 12.2 0.6 0.11 12.2 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Zn-ribbon_8 PF09723.5 EAU89852.2 - 0.49 10.3 4.1 3.4 7.6 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 EAU89852.2 - 0.6 9.5 4.6 1.8 7.9 0.3 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain YhfH PF14149.1 EAU89852.2 - 0.74 9.6 5.3 1.3 8.8 3.7 1.4 1 0 0 1 1 1 0 YhfH-like protein zf-CCHC_3 PF13917.1 EAU89852.2 - 1.2 8.8 12.5 5.2 6.8 8.7 2.0 1 1 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 EAU89855.2 - 5.3e-06 25.7 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89856.2 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 EAU89857.1 - 2.4e-07 30.2 0.0 4.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89858.1 - 6.6e-07 28.7 0.0 1.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89859.1 - 5.5e-05 22.4 0.0 9.5e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89860.1 - 1.3e-05 24.4 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain adh_short PF00106.20 EAU89862.1 - 9.9e-08 32.0 0.0 1.8e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU89862.1 - 2.4e-05 24.0 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU89862.1 - 0.0017 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.20 EAU89864.2 - 2.2e-06 26.9 0.0 3.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Big_2 PF02368.13 EAU89865.2 - 0.11 12.3 3.5 4.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Pkinase PF00069.20 EAU89867.2 - 2.9e-05 23.3 0.0 5.7e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4132 PF13569.1 EAU89869.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) Pkinase PF00069.20 EAU89870.2 - 7.6e-05 21.9 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89872.1 - 7.8e-07 28.4 0.0 1.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89873.2 - 3e-06 26.5 0.0 5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cauli_AT PF03233.8 EAU89873.2 - 0.21 11.3 0.1 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 Aphid transmission protein 7tm_4 PF13853.1 EAU89874.2 - 0.013 15.2 1.2 0.013 15.2 0.8 2.3 1 1 0 2 2 2 0 Olfactory receptor tRNA_bind_2 PF13725.1 EAU89874.2 - 0.023 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Possible tRNA binding domain UPF0114 PF03350.11 EAU89874.2 - 0.32 10.9 7.2 0.21 11.4 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 YiaAB PF05360.9 EAU89874.2 - 0.52 9.9 4.0 11 5.6 0.0 2.8 2 0 0 2 2 2 0 yiaA/B two helix domain Glyco_hydro_30 PF02055.11 EAU89877.2 - 2.6e-30 105.1 0.0 3.1e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EAU89877.2 - 0.0039 16.1 0.0 0.01 14.7 0.0 1.7 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 HMG_box PF00505.14 EAU89878.2 - 7.9e-14 51.6 0.7 1.5e-13 50.8 0.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU89878.2 - 0.0021 18.4 0.1 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 HMG-box domain Metal_resist PF13801.1 EAU89878.2 - 6.2 6.8 7.8 0.36 10.8 0.1 2.7 2 0 0 2 2 2 0 Heavy-metal resistance Pkinase PF00069.20 EAU89880.2 - 8.5e-07 28.3 0.0 2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EAU89881.2 - 3.3e-08 32.9 0.0 6.8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU89881.2 - 0.02 13.9 0.0 0.043 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase TraC PF07820.7 EAU89882.2 - 0.11 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 TraC-like protein Pkinase PF00069.20 EAU89883.2 - 1.1e-06 28.0 0.0 2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF310 PF03750.8 EAU89883.2 - 0.066 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) Pkinase_Tyr PF07714.12 EAU89883.2 - 0.07 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MscS_porin PF12795.2 EAU89884.2 - 0.079 12.2 0.2 0.079 12.2 0.2 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain PV-1 PF06637.6 EAU89884.2 - 0.14 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DivIC PF04977.10 EAU89888.2 - 0.058 12.8 0.4 0.092 12.2 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator LURAP PF14854.1 EAU89888.2 - 0.063 12.9 0.3 0.61 9.8 0.1 2.1 2 0 0 2 2 2 0 Leucine rich adaptor protein Retrotrans_gag PF03732.12 EAU89888.2 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein VD10_N PF08476.5 EAU89889.2 - 0.00016 21.0 2.8 0.16 11.4 0.1 2.6 3 0 0 3 3 3 2 Viral D10 N-terminal Retrotrans_gag PF03732.12 EAU89889.2 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein Thiolase_N PF00108.18 EAU89891.1 - 1.7e-83 279.6 1.2 1.7e-83 279.6 0.8 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAU89891.1 - 1.3e-43 147.3 0.6 1.3e-43 147.3 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EAU89891.1 - 0.00041 19.9 1.5 0.009 15.5 0.3 3.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EAU89891.1 - 0.045 13.4 0.2 15 5.3 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ICMT PF04140.9 EAU89892.1 - 1e-10 41.6 0.3 6.8e-10 39.0 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EAU89892.1 - 3.1e-07 30.4 0.7 2.8e-06 27.3 0.4 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EAU89892.1 - 1.4e-06 27.1 0.0 2.3e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Polysacc_deac_1 PF01522.16 EAU89893.2 - 1.5e-35 121.5 0.0 2.2e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase CBM_1 PF00734.13 EAU89893.2 - 1.1e-14 53.7 11.0 2.6e-14 52.5 7.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU89893.2 - 0.083 12.9 2.5 0.17 11.9 1.7 1.5 1 0 0 1 1 1 0 Toxin 7 Ank_2 PF12796.2 EAU89898.2 - 2.4e-31 107.9 0.0 1.3e-14 54.3 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EAU89898.2 - 6.6e-31 104.5 11.1 2.7e-09 36.3 0.0 7.8 7 1 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EAU89898.2 - 1.2e-27 95.7 3.1 4.1e-09 36.6 0.1 6.3 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU89898.2 - 5.7e-24 83.6 5.4 1.7e-07 31.2 0.0 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU89898.2 - 7e-21 72.2 0.3 3.6e-05 23.5 0.0 7.3 6 0 0 6 6 6 4 Ankyrin repeat AAA_22 PF13401.1 EAU89898.2 - 2.6e-05 24.3 0.1 0.00011 22.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAU89898.2 - 5.1e-05 22.9 0.0 0.00021 20.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAU89898.2 - 0.00071 19.6 0.0 0.0035 17.3 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAU89898.2 - 0.009 14.9 0.0 0.04 12.7 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.4 EAU89898.2 - 0.029 13.3 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EAU89898.2 - 0.045 13.5 0.1 0.23 11.2 0.0 2.3 2 0 0 2 2 1 0 Part of AAA domain AAA_17 PF13207.1 EAU89898.2 - 0.063 14.0 0.0 0.19 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF4205 PF13898.1 EAU89898.2 - 0.075 11.7 0.1 3.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4205) AAA PF00004.24 EAU89898.2 - 0.11 12.6 0.0 0.51 10.5 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ferric_reduct PF01794.14 EAU89899.2 - 1.3e-16 60.8 16.2 3.9e-16 59.2 11.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EAU89899.2 - 1.1e-06 28.6 0.4 0.055 13.3 0.0 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EAU89899.2 - 8e-06 26.3 0.1 3.5e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 EAU89899.2 - 0.0018 18.1 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain DUF2398 PF09661.5 EAU89906.2 - 0.038 12.7 0.0 0.041 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) YL1 PF05764.8 EAU89906.2 - 0.039 13.5 4.6 0.053 13.1 3.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.7 EAU89906.2 - 0.055 11.3 4.4 0.067 11.1 3.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 EAU89906.2 - 0.27 11.2 8.8 0.4 10.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 EAU89906.2 - 5 5.4 10.2 6.6 5.0 7.1 1.0 1 0 0 1 1 1 0 Daxx Family Sugar_tr PF00083.19 EAU89907.2 - 2e-93 313.4 19.5 2.5e-93 313.1 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU89907.2 - 3.1e-30 105.0 44.2 1.7e-27 96.0 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 EAU89907.2 - 0.054 12.9 0.2 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF697) MFS_1_like PF12832.2 EAU89907.2 - 0.12 12.1 0.2 0.12 12.1 0.1 3.9 3 1 1 4 4 4 0 MFS_1 like family DUF2530 PF10745.4 EAU89907.2 - 1.4 8.9 8.8 0.21 11.5 1.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) zf-C2H2_jaz PF12171.3 EAU89908.2 - 2.5e-11 43.3 3.6 3.7e-11 42.8 2.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EAU89908.2 - 0.00099 19.1 0.1 0.0013 18.7 0.1 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EAU89908.2 - 0.0013 18.8 1.7 0.002 18.2 1.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EAU89908.2 - 0.049 13.9 1.4 0.095 13.0 1.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU89908.2 - 0.081 13.3 0.8 0.13 12.6 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type NPDC1 PF06809.6 EAU89909.1 - 0.14 10.9 0.4 0.14 10.9 0.3 1.0 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) Lustrin_cystein PF14625.1 EAU89910.1 - 0.0092 16.0 1.0 0.0092 16.0 0.7 1.5 2 0 0 2 2 2 1 Lustrin, cysteine-rich repeated domain Nodulin_late PF07127.6 EAU89910.1 - 0.056 13.5 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 Late nodulin protein SLD3 PF08639.5 EAU89913.2 - 5.1e-09 35.2 14.7 2.5e-08 33.0 9.4 2.4 2 1 0 2 2 2 1 DNA replication regulator SLD3 F-box-like PF12937.2 EAU89914.1 - 0.0017 18.0 1.9 0.0027 17.3 0.2 2.3 2 0 0 2 2 2 1 F-box-like ATPase_gene1 PF09527.5 EAU89915.1 - 0.047 13.4 0.1 0.073 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF3313 PF11769.3 EAU89916.2 - 0.2 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) ArgJ PF01960.13 EAU89919.1 - 2.7e-140 467.2 0.4 3e-140 467.0 0.2 1.0 1 0 0 1 1 1 1 ArgJ family MFS_1 PF07690.11 EAU89933.2 - 8.4e-29 100.3 24.9 6.9e-28 97.3 18.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2762 PF10960.3 EAU89933.2 - 0.27 10.9 0.5 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) NfeD PF01957.13 EAU89933.2 - 0.28 11.3 0.0 0.28 11.3 0.0 3.3 3 1 2 5 5 5 0 NfeD-like C-terminal, partner-binding MFS_1 PF07690.11 EAU89934.2 - 8.2e-27 93.8 26.8 5.1e-26 91.2 19.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NCD3G PF07562.9 EAU89936.1 - 0.0018 17.9 0.4 0.0031 17.1 0.3 1.3 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR Mid2 PF04478.7 EAU89939.2 - 0.0035 16.7 0.1 0.0064 15.9 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM192 PF14802.1 EAU89940.2 - 1.5 7.6 0.0 4.4 6.0 0.0 1.8 1 0 0 1 1 1 0 TMEM192 family GMC_oxred_N PF00732.14 EAU89943.2 - 1.6e-48 165.3 0.2 1.7e-47 162.0 0.1 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU89943.2 - 3.8e-31 108.3 0.0 5.9e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase SUR7 PF06687.7 EAU89944.2 - 2.6e-12 46.7 1.2 3e-12 46.5 0.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EAU89944.2 - 0.00022 20.9 2.1 0.00026 20.7 1.5 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction G2F PF07474.7 EAU89944.2 - 0.0083 15.5 0.2 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 G2F domain Peroxidase_2 PF01328.12 EAU89945.1 - 7.1e-20 70.9 0.3 4.5e-19 68.2 0.2 1.9 1 1 0 1 1 1 1 Peroxidase, family 2 GATA PF00320.22 EAU89948.1 - 2.3e-07 30.0 7.9 2.3e-07 30.0 5.5 2.2 2 0 0 2 2 2 1 GATA zinc finger DUF4064 PF13273.1 EAU89950.2 - 1.8 8.7 7.2 1.1 9.4 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) zf-C2HC5 PF06221.8 EAU89952.2 - 1.6e-14 53.3 2.7 2.3e-14 52.8 1.9 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Zn_ribbon_2 PF12674.2 EAU89964.1 - 0.087 13.1 1.5 0.23 11.8 1.1 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-B_box PF00643.19 EAU89964.1 - 5.7 6.9 7.9 3.5 7.6 3.2 2.4 2 0 0 2 2 2 0 B-box zinc finger RhoGEF PF00621.15 EAU89965.2 - 5.9e-36 124.0 0.0 8.7e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EAU89965.2 - 6.3e-07 29.5 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PC-Esterase PF13839.1 EAU89966.1 - 7.4e-08 32.5 3.5 5.3e-07 29.7 2.4 2.1 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Peptidase_M28 PF04389.12 EAU89967.1 - 1.4e-32 112.9 0.0 2.2e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAU89967.1 - 5e-11 42.1 1.3 1.3e-10 40.8 0.4 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M42 PF05343.9 EAU89967.1 - 0.13 11.0 0.1 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase ZZ PF00569.12 EAU89970.1 - 0.00017 21.0 11.6 0.00017 21.0 8.1 2.9 3 0 0 3 3 3 1 Zinc finger, ZZ type BSP_II PF05432.6 EAU89970.1 - 0.00046 19.5 23.2 0.001 18.4 16.1 1.5 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SAICAR_synt PF01259.13 EAU89971.1 - 2.7e-89 298.5 0.0 3.4e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase MKT1_C PF12246.3 EAU89975.2 - 3.5e-59 199.7 0.0 4.7e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EAU89975.2 - 6.9e-24 83.9 0.0 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EAU89975.2 - 3.2e-14 52.7 0.0 6.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAU89975.2 - 4.5e-09 36.4 0.0 9.2e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Pescadillo_N PF06732.6 EAU89975.2 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Pescadillo N-terminus zf-C2H2_jaz PF12171.3 EAU89976.2 - 0.01 15.9 0.5 0.023 14.8 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAU89976.2 - 0.083 12.8 0.5 0.18 11.7 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU89976.2 - 0.093 13.1 0.3 0.35 11.3 0.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU89976.2 - 0.15 12.4 0.9 0.48 10.8 0.6 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4611 PF15387.1 EAU89976.2 - 3.6 7.8 8.8 0.5 10.5 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pirin PF02678.11 EAU89978.1 - 7e-26 90.2 1.7 1.2e-25 89.3 1.2 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EAU89978.1 - 4.1e-10 39.0 0.9 1.1e-05 24.8 0.3 2.3 2 0 0 2 2 2 2 Cupin domain WD40 PF00400.27 EAU89979.2 - 2.7e-85 277.5 25.1 3.3e-12 45.7 0.2 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EAU89979.2 - 2.9e-09 36.8 0.2 5e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EAU89979.2 - 9.4e-06 24.0 8.4 0.11 10.5 0.1 4.3 4 1 0 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EAU89979.2 - 0.031 13.0 3.3 8.5 4.9 0.0 3.6 2 2 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 EAU89979.2 - 0.049 12.9 0.1 5.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Opi1 PF08618.5 EAU89980.1 - 7.2e-70 236.0 14.3 1.6e-57 195.3 3.8 2.1 2 0 0 2 2 2 2 Transcription factor Opi1 Perilipin PF03036.11 EAU89980.1 - 6.3e-05 21.9 0.0 0.00017 20.5 0.0 1.7 2 0 0 2 2 2 1 Perilipin family REF PF05755.7 EAU89980.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Peptidase_C2 PF00648.16 EAU89981.2 - 6.4e-31 107.4 0.5 3.4e-18 65.6 0.2 2.5 2 1 0 2 2 2 2 Calpain family cysteine protease zf-C2H2 PF00096.21 EAU89982.2 - 0.00013 22.0 1.9 0.00036 20.7 1.3 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU89982.2 - 0.052 13.8 1.0 0.14 12.6 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger GATA PF00320.22 EAU89984.2 - 8.2e-17 60.2 3.5 2.1e-16 58.9 2.4 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EAU89984.2 - 0.074 12.3 1.1 0.15 11.4 0.7 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Halogen_Hydrol PF10112.4 EAU89984.2 - 0.14 11.5 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein GATA PF00320.22 EAU89985.2 - 2.4e-13 49.1 2.5 4.2e-13 48.4 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EAU89985.2 - 0.019 14.3 0.2 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Dioxygenase_C PF00775.16 EAU89986.1 - 7.9e-13 48.0 0.2 1.4e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 Dioxygenase Ribosomal_L37e PF01907.14 EAU89987.1 - 2.3e-25 88.1 12.3 3.9e-25 87.4 8.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EAU89987.1 - 0.00036 20.2 2.4 0.00056 19.6 1.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EAU89987.1 - 0.013 15.2 0.3 0.016 14.8 0.2 1.4 1 1 0 1 1 1 0 SelR domain LIM PF00412.17 EAU89987.1 - 0.031 14.3 2.1 0.044 13.8 1.5 1.3 1 0 0 1 1 1 0 LIM domain HypA PF01155.14 EAU89987.1 - 0.062 12.9 1.0 0.088 12.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 EAU89987.1 - 0.18 11.3 3.8 1.7 8.1 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EAU89987.1 - 0.27 10.4 3.4 0.95 8.7 2.5 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.1 EAU89987.1 - 0.41 10.3 4.7 0.66 9.7 3.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain GFA PF04828.9 EAU89987.1 - 0.6 10.0 4.8 4.3 7.3 3.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4 PF00097.20 EAU89987.1 - 1.4 8.6 5.7 2.3 7.9 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_S14 PF00253.16 EAU89987.1 - 2.6 7.5 9.7 3.2 7.1 0.2 2.7 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e zf-C3HC4_2 PF13923.1 EAU89987.1 - 2.7 8.1 5.5 4.4 7.4 3.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.1 EAU89987.1 - 3.5 7.4 5.4 2.7 7.8 0.7 2.2 1 1 1 2 2 2 0 YhfH-like protein Peptidase_C2 PF00648.16 EAU89990.2 - 8.8e-57 192.3 0.6 8.3e-39 133.3 0.1 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease SoxE PF06525.6 EAU89990.2 - 0.018 14.3 0.9 0.018 14.3 0.6 2.7 3 0 0 3 3 3 0 Sulfocyanin (SoxE) Catalase PF00199.14 EAU89992.2 - 1.9e-146 487.6 0.1 2.5e-146 487.2 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EAU89992.2 - 5e-09 35.8 0.1 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ank_2 PF12796.2 EAU89993.2 - 2.1e-43 146.5 13.9 1.7e-13 50.7 0.6 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU89993.2 - 7.1e-34 115.0 7.3 4e-09 36.4 0.1 6.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EAU89993.2 - 1.3e-30 103.6 10.0 1.2e-06 28.0 0.0 9.0 8 1 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EAU89993.2 - 1.3e-30 105.1 4.9 1.3e-07 31.9 0.0 6.8 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU89993.2 - 2.9e-26 88.8 2.3 0.00084 19.3 0.0 9.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_2 PF12796.2 EAU89994.2 - 1.9e-40 137.0 6.1 2e-11 44.0 0.5 6.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EAU89994.2 - 2.7e-38 127.8 8.6 4.1e-07 29.4 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EAU89994.2 - 4e-35 119.5 8.8 7.7e-09 35.8 0.0 7.3 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU89994.2 - 1.2e-30 104.8 13.9 4.5e-08 33.0 0.1 7.4 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU89994.2 - 6.3e-28 94.0 2.6 6.1e-05 22.8 0.0 10.0 10 0 0 10 10 9 5 Ankyrin repeat NACHT PF05729.7 EAU89994.2 - 3.3e-07 30.1 0.1 7.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU89994.2 - 1.3e-06 28.5 0.8 8.4e-06 25.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EAU89994.2 - 9.5e-06 25.7 0.1 5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAU89994.2 - 1.6e-05 23.9 0.0 0.0022 16.9 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain DUF362 PF04015.7 EAU89994.2 - 0.0089 15.5 0.0 0.055 12.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF362) DUF2075 PF09848.4 EAU89994.2 - 0.01 14.8 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EAU89994.2 - 0.028 14.1 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 NTPase ArsC PF03960.10 EAU89994.2 - 0.12 12.4 0.0 0.42 10.7 0.0 1.9 1 0 0 1 1 1 0 ArsC family Pro-kuma_activ PF09286.6 EAU89995.2 - 2.2e-22 79.6 0.0 5e-21 75.2 0.0 2.7 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EAU89995.2 - 0.00047 19.4 0.1 0.00071 18.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Ammonium_transp PF00909.16 EAU89998.2 - 1.5e-109 366.1 24.2 1.8e-109 365.8 16.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Methyltransf_11 PF08241.7 EAU89999.2 - 1.8e-12 47.5 0.0 3.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU89999.2 - 4.9e-08 32.3 0.0 7.5e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EAU89999.2 - 5.5e-08 32.6 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU89999.2 - 3e-07 30.7 0.0 5.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU89999.2 - 5.4e-07 30.1 0.0 2.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU89999.2 - 1.3e-05 24.8 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU89999.2 - 0.00025 21.4 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU89999.2 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EAU89999.2 - 0.072 11.4 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.7 EAU89999.2 - 0.095 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.14 EAU89999.2 - 0.23 11.4 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Phage_integrase PF00589.17 EAU89999.2 - 0.38 10.4 1.1 0.72 9.5 0.2 1.7 2 0 0 2 2 2 0 Phage integrase family Peptidase_M28 PF04389.12 EAU90001.1 - 1.3e-28 99.9 0.0 2.3e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAU90001.1 - 2e-08 33.9 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DNA_gyraseA_C PF03989.8 EAU90001.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller Peptidase_M28 PF04389.12 EAU90002.1 - 2.2e-30 105.7 0.0 3.8e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAU90002.1 - 2.1e-07 30.6 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EAU90002.1 - 0.014 14.1 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase UQ_con PF00179.21 EAU90003.2 - 5.4e-24 84.2 0.0 8.2e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Thymidylate_kin PF02223.12 EAU90004.2 - 1.1e-34 119.4 0.0 5.2e-34 117.2 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EAU90004.2 - 0.0049 16.1 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EAU90004.2 - 0.015 15.3 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EAU90005.1 - 4.5e-38 130.8 35.0 4.5e-38 130.8 24.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAU90005.1 - 0.0025 17.5 2.9 0.0052 16.5 0.8 2.7 2 0 0 2 2 2 1 MFS_1 like family EPL1 PF10513.4 EAU90006.2 - 6.3e-16 59.0 1.1 1.4e-15 57.9 0.0 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like DNA_gyraseB PF00204.20 EAU90006.2 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 DNA gyrase B Peptidase_M28 PF04389.12 EAU90007.1 - 3.7e-34 118.0 0.0 6e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAU90007.1 - 5.9e-13 48.3 2.1 9e-13 47.7 0.5 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EAU90007.1 - 0.00015 21.3 0.0 0.00042 19.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EAU90007.1 - 0.016 14.0 0.2 0.091 11.5 0.0 1.9 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase DUF2263 PF10021.4 EAU90008.2 - 7e-17 61.7 0.0 1.1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Peptidase_M28 PF04389.12 EAU90009.1 - 4.6e-33 114.4 0.0 7.5e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EAU90009.1 - 1.5e-13 50.2 0.9 6e-13 48.3 0.3 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M42 PF05343.9 EAU90009.1 - 0.085 11.6 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Ank_2 PF12796.2 EAU90010.2 - 3.7e-83 273.9 20.6 2.8e-13 49.9 0.0 9.3 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90010.2 - 1.9e-65 213.5 18.3 4.2e-06 26.2 0.0 14.6 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 EAU90010.2 - 3.6e-59 196.1 9.4 1.9e-10 40.9 0.2 11.1 4 2 8 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90010.2 - 4.3e-56 185.6 10.8 5.1e-09 36.0 0.0 11.1 4 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90010.2 - 1.8e-44 145.3 13.1 0.00096 19.1 0.0 14.6 15 0 0 15 15 14 10 Ankyrin repeat DUF3107 PF11305.3 EAU90010.2 - 3.6e-05 23.5 2.0 5.1 7.0 0.0 5.6 3 2 2 5 5 5 2 Protein of unknown function (DUF3107) NACHT PF05729.7 EAU90010.2 - 0.00064 19.4 0.0 0.0026 17.4 0.0 2.1 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAU90010.2 - 0.0099 15.8 0.4 0.19 11.7 0.0 3.1 2 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EAU90010.2 - 0.0099 16.0 0.0 0.089 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain SchA_CurD PF04486.7 EAU90010.2 - 0.015 15.1 0.0 1.5 8.6 0.0 3.6 4 0 0 4 4 4 0 SchA/CurD like domain DUF2075 PF09848.4 EAU90010.2 - 0.05 12.5 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EAU90010.2 - 0.051 12.4 0.0 0.13 11.0 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain CAF-1_p150 PF11600.3 EAU90012.2 - 0.13 11.6 10.3 0.25 10.6 7.2 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ank_2 PF12796.2 EAU90013.1 - 1.1e-89 294.8 39.1 4.1e-14 52.6 0.0 10.6 1 1 12 13 13 13 13 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90013.1 - 3.2e-75 244.4 28.9 1.4e-05 24.6 0.0 18.0 18 1 0 18 18 18 15 Ankyrin repeat Ank_4 PF13637.1 EAU90013.1 - 5.9e-69 227.3 14.8 5.3e-10 39.5 0.1 13.6 4 3 11 15 15 15 14 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90013.1 - 2.9e-68 224.3 21.3 2.9e-10 40.0 0.0 12.6 6 3 5 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90013.1 - 3.6e-48 156.7 5.2 0.00062 19.7 0.0 17.2 17 0 0 17 17 16 9 Ankyrin repeat AAA_22 PF13401.1 EAU90013.1 - 2.6e-06 27.6 0.1 3.4e-05 23.9 0.0 3.0 3 1 1 4 4 4 1 AAA domain AAA_16 PF13191.1 EAU90013.1 - 9.1e-05 22.5 0.3 0.0013 18.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAU90013.1 - 0.00041 19.3 0.0 0.0016 17.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 EAU90013.1 - 0.0016 18.1 0.0 0.0047 16.6 0.0 1.9 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EAU90013.1 - 0.019 13.9 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EAU90013.1 - 0.028 14.1 0.0 0.1 12.3 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EAU90013.1 - 0.035 14.3 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3881 PF12997.2 EAU90013.1 - 0.05 12.6 0.1 7.8 5.4 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) ApoC-I PF04691.7 EAU90013.1 - 0.074 12.7 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) LRR_7 PF13504.1 EAU90014.2 - 0.12 12.6 0.7 32 5.3 0.0 3.9 3 0 0 3 3 3 0 Leucine rich repeat Ank_2 PF12796.2 EAU90015.2 - 5.3e-99 324.7 51.0 7.9e-15 54.9 0.7 8.9 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU90015.2 - 1.4e-66 219.7 26.1 1.4e-10 41.3 0.0 12.6 1 1 13 14 14 14 13 Ankyrin repeats (many copies) Ank PF00023.25 EAU90015.2 - 5.9e-60 196.2 33.3 0.00054 19.6 0.1 15.5 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.1 EAU90015.2 - 4.5e-49 163.3 32.6 5.7e-08 32.7 0.4 11.4 4 2 8 13 13 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90015.2 - 4.7e-41 134.6 23.0 0.0053 16.8 0.0 15.7 15 0 0 15 15 15 10 Ankyrin repeat SchA_CurD PF04486.7 EAU90015.2 - 5.7e-08 32.5 5.7 1.2 8.9 0.0 6.7 2 1 1 5 5 5 3 SchA/CurD like domain NACHT PF05729.7 EAU90015.2 - 1.7e-06 27.7 0.1 6.3e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU90015.2 - 8.1e-06 25.9 0.5 6.7e-05 22.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU90015.2 - 3.4e-05 24.0 0.0 0.00015 21.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain Nbl1_Borealin_N PF10444.4 EAU90015.2 - 3.7e-05 22.9 1.3 4.3 6.7 0.0 5.5 5 1 2 7 7 7 1 Nbl1 / Borealin N terminal DUF3107 PF11305.3 EAU90015.2 - 0.00035 20.3 11.1 20 5.1 0.1 8.8 7 2 4 11 11 11 0 Protein of unknown function (DUF3107) TPR_20 PF14561.1 EAU90015.2 - 0.0013 18.7 16.2 0.35 11.0 0.1 6.0 4 2 2 6 6 6 1 Tetratricopeptide repeat DnaB_C PF03796.10 EAU90015.2 - 0.0057 15.5 0.0 16 4.2 0.0 4.5 3 1 1 5 5 5 0 DnaB-like helicase C terminal domain NB-ARC PF00931.17 EAU90015.2 - 0.006 15.4 0.0 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 EAU90015.2 - 0.027 13.4 0.0 0.059 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EAU90015.2 - 0.13 13.0 1.3 2.4 8.9 0.0 3.4 3 2 0 3 3 3 0 AAA domain DUF3881 PF12997.2 EAU90015.2 - 0.16 10.9 6.6 11 4.9 0.2 4.3 2 1 2 4 4 4 0 Domain of unknown function, E. rectale Gene description (DUF3881) CTNNBL PF08216.6 EAU90015.2 - 4 7.0 10.9 42 3.7 0.1 5.4 6 0 0 6 6 6 0 Catenin-beta-like, Arm-motif containing nuclear Ank_2 PF12796.2 EAU90016.2 - 4.8e-34 116.5 3.5 3.2e-12 46.6 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU90016.2 - 5.4e-30 102.7 11.3 1.5e-08 34.5 0.1 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EAU90016.2 - 7.1e-30 101.3 13.5 2.2e-05 24.0 0.1 8.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EAU90016.2 - 3.6e-26 91.0 9.8 9.9e-08 32.3 0.1 7.3 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90016.2 - 9.3e-22 74.9 4.8 0.0015 18.5 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat AAA_22 PF13401.1 EAU90016.2 - 1.6e-05 25.0 0.0 5.3e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAU90016.2 - 0.00022 20.9 0.3 0.0016 18.1 0.1 2.4 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EAU90016.2 - 0.00097 18.0 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Nbl1_Borealin_N PF10444.4 EAU90016.2 - 0.14 11.5 0.1 18 4.7 0.0 2.8 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Pro_isomerase PF00160.16 EAU90017.2 - 2.7e-38 131.6 0.0 2.7e-38 131.6 0.0 2.5 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UQ_con PF00179.21 EAU90018.2 - 4.9e-18 64.9 0.0 5.5e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EAU90018.2 - 0.0031 17.3 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain VHS PF00790.14 EAU90019.1 - 1.5e-30 105.6 0.1 3e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 EAU90019.1 - 2e-15 56.0 0.1 4.3e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU90019.1 - 4.4e-14 51.7 0.1 7.6e-14 50.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EAU90019.1 - 5.8e-14 51.2 0.0 1.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain GAT PF03127.9 EAU90019.1 - 1.5e-07 31.2 1.2 4.4e-07 29.7 0.9 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.15 EAU90019.1 - 0.0013 18.1 0.3 0.0038 16.6 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif HEAT_2 PF13646.1 EAU90019.1 - 0.09 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 HEAT repeats DUF445 PF04286.7 EAU90019.1 - 0.13 11.7 3.3 0.75 9.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Ank_2 PF12796.2 EAU90021.1 - 4.4e-61 203.2 35.8 3.2e-11 43.4 1.1 6.5 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90021.1 - 6.5e-45 148.7 31.4 2.1e-05 24.0 0.1 11.7 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 EAU90021.1 - 2.1e-43 145.3 26.5 6.2e-09 35.8 0.5 8.1 5 1 4 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU90021.1 - 2.2e-36 123.5 18.3 3.6e-07 30.5 0.0 10.0 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90021.1 - 6.4e-27 90.9 19.8 0.017 15.3 0.0 10.9 11 0 0 11 11 11 7 Ankyrin repeat AAA_22 PF13401.1 EAU90021.1 - 5.7e-06 26.4 0.2 3e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAU90021.1 - 0.00025 20.7 0.3 0.00095 18.8 0.1 2.0 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EAU90021.1 - 0.00038 19.4 0.0 0.00076 18.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TRAP-delta PF05404.7 EAU90021.1 - 0.0022 17.4 0.0 23 4.3 0.0 4.0 4 1 0 4 4 4 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) DUF3107 PF11305.3 EAU90021.1 - 0.18 11.7 0.9 8.8 6.2 0.0 3.7 3 2 1 4 4 4 0 Protein of unknown function (DUF3107) Exo_endo_phos PF03372.18 EAU90023.1 - 2e-18 67.2 0.0 5.5e-18 65.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EAU90023.1 - 3.8e-10 39.4 0.0 1.5e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EAU90023.1 - 1.1e-05 25.2 2.2 2.7e-05 24.0 1.5 1.7 1 0 0 1 1 1 1 GRF zinc finger Peptidase_C2 PF00648.16 EAU90024.2 - 9.7e-55 185.6 3.3 5.8e-37 127.2 0.4 2.5 3 0 0 3 3 3 2 Calpain family cysteine protease DAP3 PF10236.4 EAU90026.1 - 2.1e-63 214.0 0.0 2.6e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 EAU90026.1 - 4.4e-07 29.8 0.0 9.6e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EAU90026.1 - 9.2e-07 29.0 0.1 3.7e-06 27.0 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EAU90026.1 - 0.0028 17.0 0.0 0.0079 15.6 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 EAU90026.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EAU90026.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 EAU90026.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.1 EAU90026.1 - 0.043 12.4 0.0 0.27 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Bac_DnaA PF00308.13 EAU90026.1 - 0.058 13.0 0.0 6.8 6.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.1 EAU90026.1 - 0.067 13.3 0.0 0.28 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EAU90026.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EAU90026.1 - 0.1 12.4 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 EAU90027.2 - 3.4e-49 165.1 21.3 2.5e-11 43.7 0.0 5.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90027.2 - 1.1e-37 125.9 20.6 0.00029 20.5 0.1 9.8 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EAU90027.2 - 9.9e-32 108.7 9.2 7.4e-07 29.5 0.0 7.9 3 2 7 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90027.2 - 1.5e-30 104.4 18.4 2.4e-05 24.4 0.1 7.4 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90027.2 - 7.5e-23 78.3 7.7 0.0035 17.4 0.0 9.7 9 0 0 9 9 9 6 Ankyrin repeat AAA_22 PF13401.1 EAU90027.2 - 1.9e-06 28.0 0.0 6.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAU90027.2 - 1.3e-05 24.1 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EAU90027.2 - 1.7e-05 24.5 0.1 5.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EAU90027.2 - 0.0051 16.8 0.1 0.018 14.9 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain Nbl1_Borealin_N PF10444.4 EAU90027.2 - 0.011 15.0 0.6 27 4.2 0.0 4.3 3 1 1 4 4 4 0 Nbl1 / Borealin N terminal DUF1949 PF09186.6 EAU90027.2 - 0.026 14.0 0.3 60 3.3 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1949) Mg_chelatase PF01078.16 EAU90027.2 - 0.038 13.1 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Nitro_FeMo-Co PF02579.12 EAU90027.2 - 0.28 11.2 1.4 71 3.5 0.0 4.0 2 1 2 4 4 4 0 Dinitrogenase iron-molybdenum cofactor Pro_isomerase PF00160.16 EAU90030.2 - 5.2e-18 65.7 0.0 2e-16 60.5 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_2 PF12796.2 EAU90032.2 - 5.2e-44 148.4 12.5 5e-13 49.1 0.4 3.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90032.2 - 1.3e-28 97.3 6.7 0.00026 20.6 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EAU90032.2 - 1.5e-19 69.5 3.9 1.2e-05 25.4 0.0 5.4 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU90032.2 - 3.4e-17 62.4 2.0 1.4e-06 28.6 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90032.2 - 4.4e-16 57.3 0.4 0.045 14.0 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat NB-ARC PF00931.17 EAU90032.2 - 5.1e-07 28.8 0.0 2.5e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.1 EAU90032.2 - 3.4e-06 27.2 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EAU90032.2 - 2.2e-05 24.1 0.0 5.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.16 EAU90032.2 - 0.027 13.6 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EAU90032.2 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ank_2 PF12796.2 EAU90033.2 - 6e-38 129.0 13.0 6.1e-12 45.7 0.2 5.2 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU90033.2 - 2.2e-33 114.0 11.6 6.3e-07 29.7 0.0 7.8 3 3 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 EAU90033.2 - 5.8e-32 107.9 20.3 5.5e-06 25.9 0.1 9.7 9 1 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 EAU90033.2 - 6.7e-24 83.3 17.5 6.5e-08 32.5 0.1 6.6 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90033.2 - 1.4e-19 68.1 4.4 0.00094 19.2 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Nitro_FeMo-Co PF02579.12 EAU90033.2 - 4.7e-05 23.3 1.7 0.53 10.3 0.0 5.3 4 2 1 6 6 6 1 Dinitrogenase iron-molybdenum cofactor DUF3035 PF11233.3 EAU90033.2 - 0.0032 17.5 2.7 2 8.4 0.1 3.4 2 1 0 3 3 3 2 Protein of unknown function (DUF3035) SchA_CurD PF04486.7 EAU90033.2 - 0.0032 17.2 0.7 20 5.0 0.0 4.7 3 2 1 5 5 5 0 SchA/CurD like domain Nbl1_Borealin_N PF10444.4 EAU90033.2 - 0.018 14.4 0.0 12 5.3 0.0 3.8 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal DUF1949 PF09186.6 EAU90033.2 - 0.11 12.0 1.1 9 5.9 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF1949) DAP3 PF10236.4 EAU90034.2 - 2.9e-05 23.1 0.0 4.8e-05 22.4 0.0 1.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Ank_2 PF12796.2 EAU90036.2 - 5.7e-39 132.3 1.0 1.6e-10 41.1 0.0 5.3 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90036.2 - 2.3e-36 121.8 1.4 1.4e-05 24.6 0.0 9.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EAU90036.2 - 4e-32 109.9 0.5 4.4e-10 39.7 0.0 7.4 3 1 5 8 8 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90036.2 - 2.5e-25 87.9 7.4 3.7e-07 30.1 0.0 6.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90036.2 - 4.8e-25 85.1 1.5 0.021 15.0 0.0 8.8 9 0 0 9 9 8 6 Ankyrin repeat AAA_22 PF13401.1 EAU90036.2 - 5.6e-06 26.5 0.0 2.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EAU90036.2 - 9.5e-06 25.3 0.1 2.2e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU90036.2 - 3.1e-05 24.0 0.1 0.00011 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EAU90036.2 - 3.9e-05 22.6 0.0 7.9e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain SchA_CurD PF04486.7 EAU90036.2 - 0.00046 19.9 0.6 5.9 6.7 0.0 4.1 3 1 1 4 4 4 2 SchA/CurD like domain DUF1998 PF09369.5 EAU90036.2 - 0.0038 17.7 0.6 7.8 7.1 0.0 4.2 2 1 3 5 5 5 1 Domain of unknown function (DUF1998) AAA_28 PF13521.1 EAU90036.2 - 0.012 15.5 2.9 0.61 10.0 0.3 3.5 2 2 1 3 3 3 0 AAA domain DUF2075 PF09848.4 EAU90036.2 - 0.022 13.7 0.0 0.057 12.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF3107 PF11305.3 EAU90036.2 - 0.041 13.7 0.3 82 3.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3107) Ank_2 PF12796.2 EAU90037.2 - 3.2e-79 261.3 24.6 1e-14 54.6 0.0 9.0 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU90037.2 - 3.3e-69 228.1 7.1 2.5e-09 37.4 0.0 12.2 6 3 7 13 13 13 13 Ankyrin repeats (many copies) Ank PF00023.25 EAU90037.2 - 1.9e-65 213.5 27.4 7.5e-05 22.3 0.0 16.0 16 0 0 16 16 16 13 Ankyrin repeat Ank_5 PF13857.1 EAU90037.2 - 1.7e-58 193.3 16.7 6.4e-08 32.5 0.0 12.0 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90037.2 - 3.9e-48 156.6 9.4 0.0014 18.6 0.0 15.9 16 0 0 16 16 15 9 Ankyrin repeat AAA_22 PF13401.1 EAU90037.2 - 2.2e-06 27.8 0.0 1.4e-05 25.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU90037.2 - 2.7e-05 24.2 0.3 0.00013 22.0 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain NapD PF03927.8 EAU90037.2 - 0.00032 20.4 0.8 1.7 8.5 0.1 4.1 4 0 0 4 4 4 1 NapD protein NACHT PF05729.7 EAU90037.2 - 0.02 14.5 0.0 0.051 13.2 0.0 1.7 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EAU90037.2 - 0.027 13.4 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EAU90037.2 - 0.032 13.9 0.0 0.16 11.7 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EAU90037.2 - 0.052 13.7 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EAU90037.2 - 0.058 12.2 0.0 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.1 EAU90037.2 - 0.11 13.3 0.0 0.39 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.2 EAU90039.1 - 0.00065 19.3 0.0 0.0021 17.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like PAT1 PF09770.4 EAU90042.1 - 0.31 9.2 19.4 0.51 8.5 13.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_11 PF13414.1 EAU90043.1 - 4.5e-16 58.2 4.6 4.3e-12 45.4 0.3 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAU90043.1 - 7e-11 41.1 2.3 0.016 15.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAU90043.1 - 7.7e-07 28.9 0.8 0.00067 19.5 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90043.1 - 1.6e-05 24.2 4.6 0.54 9.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU90043.1 - 9.8e-05 22.9 8.4 0.029 15.0 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU90043.1 - 0.0026 18.2 4.7 3.6 8.4 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU90043.1 - 0.0029 17.2 1.3 0.62 9.9 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAU90043.1 - 0.0044 16.8 1.3 1.1 9.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU90043.1 - 0.0083 16.2 0.7 0.058 13.5 0.5 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EAU90043.1 - 0.02 15.0 1.6 26 5.3 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAU90043.1 - 0.056 13.7 5.9 1.5 9.2 1.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EAU90043.1 - 0.08 12.8 1.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DEAD PF00270.24 EAU90044.1 - 4.5e-45 153.1 0.0 1.3e-44 151.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU90044.1 - 2.6e-26 91.3 0.1 6.2e-26 90.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU90044.1 - 0.0022 17.8 0.0 0.0046 16.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EAU90044.1 - 0.24 10.4 0.0 0.41 9.6 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Spt20 PF12090.3 EAU90045.1 - 2.9e-36 124.5 0.0 2.9e-36 124.5 0.0 5.5 3 1 0 3 3 3 1 Spt20 family DNA_binding_1 PF01035.15 EAU90046.2 - 7.7e-24 83.2 0.0 9.7e-24 82.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain GWT1 PF06423.7 EAU90047.2 - 2.6 8.1 8.3 0.68 10.0 1.0 2.3 2 0 0 2 2 2 0 GWT1 Ank_2 PF12796.2 EAU90048.1 - 1.9e-16 60.1 0.8 2.3e-09 37.4 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU90048.1 - 7e-14 51.5 3.6 9.9e-10 38.3 0.4 3.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EAU90048.1 - 1.9e-13 49.4 4.0 9.9e-09 34.5 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EAU90048.1 - 2.4e-12 45.8 0.4 2.3e-06 27.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EAU90048.1 - 8.9e-12 45.1 2.9 4.3e-05 23.8 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Chromo PF00385.19 EAU90049.2 - 7.5e-12 44.7 0.5 2.1e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EAU90049.2 - 7.6e-09 35.2 0.0 7.6e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Tudor-knot PF11717.3 EAU90049.2 - 0.1 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MRC1 PF09444.5 EAU90049.2 - 0.12 12.6 13.3 0.27 11.5 9.0 1.7 1 1 0 1 1 1 0 MRC1-like domain RRM_1 PF00076.17 EAU90050.2 - 7.8e-16 57.4 0.0 1.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU90050.2 - 9.7e-13 47.9 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU90050.2 - 3.2e-08 33.2 0.0 5.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU90050.2 - 0.01 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif zf-MYND PF01753.13 EAU90051.2 - 2e-08 33.9 14.8 4e-08 32.9 10.3 1.5 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 EAU90051.2 - 0.00031 20.4 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) zf-Mss51 PF13824.1 EAU90051.2 - 1.3 8.8 9.8 3.7 7.4 6.8 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 EAU90051.2 - 1.9 8.2 8.3 5 6.8 5.7 1.8 1 0 0 1 1 1 0 HIT zinc finger Coprogen_oxidas PF01218.13 EAU90055.1 - 5.1e-117 389.6 0.1 2e-85 285.9 0.1 2.3 2 0 0 2 2 2 2 Coproporphyrinogen III oxidase Glutaredoxin PF00462.19 EAU90056.1 - 1.6e-17 63.1 0.0 4.2e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin YcbB PF08664.5 EAU90058.1 - 0.11 12.2 0.5 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 YcbB domain GFA PF04828.9 EAU90059.1 - 1.9e-20 72.6 0.1 2.5e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EAU90059.1 - 0.062 12.5 2.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain MFS_1 PF07690.11 EAU90060.1 - 1.9e-28 99.1 39.8 1.9e-28 99.1 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPMT PF05724.6 EAU90061.1 - 4.8e-35 120.9 0.0 5.5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EAU90061.1 - 4e-13 49.2 0.0 5.7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU90061.1 - 2.3e-12 47.4 0.0 6.3e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU90061.1 - 2.2e-11 44.0 0.0 3.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU90061.1 - 6.8e-10 39.0 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU90061.1 - 2.2e-09 37.5 0.0 3.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU90061.1 - 7.1e-09 36.0 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU90061.1 - 7.1e-08 32.3 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EAU90061.1 - 0.00013 21.1 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EAU90061.1 - 0.0052 16.1 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EAU90061.1 - 0.044 12.8 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EAU90061.1 - 0.048 13.3 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EAU90061.1 - 0.061 12.6 0.3 3.5 6.8 0.0 2.8 2 1 0 3 3 3 0 CheR methyltransferase, SAM binding domain PCMT PF01135.14 EAU90061.1 - 0.087 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pyr_redox_3 PF13738.1 EAU90062.2 - 6.1e-24 85.2 0.0 1.6e-23 83.8 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAU90062.2 - 3.3e-20 71.8 0.0 3.3e-13 48.7 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EAU90062.2 - 3.8e-10 39.9 0.0 3.5e-09 36.8 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EAU90062.2 - 4e-08 32.5 0.1 1.8e-06 27.1 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EAU90062.2 - 1.7e-05 24.7 0.1 6.3e-05 22.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EAU90062.2 - 4.6e-05 22.6 0.2 0.00015 20.9 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EAU90062.2 - 0.00027 19.9 0.2 0.0017 17.3 0.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EAU90062.2 - 0.001 18.2 0.3 0.03 13.4 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 EAU90062.2 - 0.002 18.4 0.0 0.18 12.2 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EAU90062.2 - 0.0021 17.1 0.2 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EAU90062.2 - 0.031 13.1 0.3 0.06 12.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EAU90062.2 - 0.046 13.4 1.2 15 5.2 0.2 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EAU90062.2 - 0.066 12.1 0.2 0.48 9.2 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EAU90062.2 - 0.086 11.6 0.4 0.92 8.2 0.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EAU90062.2 - 0.2 10.1 0.4 0.48 8.8 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EAU90063.2 - 1.1e-11 45.1 0.0 7.3e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU90063.2 - 6.9e-08 32.6 0.0 3.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU90063.2 - 3.4e-05 23.7 0.0 7.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EAU90063.2 - 8.9e-05 21.7 0.0 0.00014 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAU90063.2 - 0.00036 19.5 0.0 0.037 12.9 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FMO-like PF00743.14 EAU90063.2 - 0.00061 18.1 0.0 0.14 10.2 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EAU90063.2 - 0.0021 17.2 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EAU90063.2 - 0.0064 16.2 0.2 0.87 9.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EAU90063.2 - 0.0077 15.1 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EAU90063.2 - 0.01 16.1 0.1 0.096 13.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAU90063.2 - 0.017 14.0 0.0 0.033 13.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EAU90063.2 - 0.021 13.3 0.0 0.065 11.6 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EAU90063.2 - 0.026 13.6 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 EAU90063.2 - 0.048 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 EAU90063.2 - 0.098 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Gly_transf_sug PF04488.10 EAU90070.2 - 6.6e-07 29.6 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EAU90070.2 - 0.006 15.7 0.3 0.0094 15.1 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein zf-DNL PF05180.7 EAU90071.2 - 1.3e-25 88.9 0.8 1.6e-25 88.5 0.6 1.1 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.13 EAU90071.2 - 0.019 14.6 1.6 0.035 13.7 1.1 1.5 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) YCII PF03795.9 EAU90071.2 - 0.088 13.0 0.1 0.12 12.5 0.1 1.3 1 1 0 1 1 1 0 YCII-related domain HEAT_2 PF13646.1 EAU90073.2 - 1.8e-14 53.7 8.3 0.0035 17.5 0.1 7.3 7 2 1 8 8 8 4 HEAT repeats Adaptin_N PF01602.15 EAU90073.2 - 2e-11 42.9 1.7 0.00063 18.1 0.0 3.9 3 1 1 4 4 4 2 Adaptin N terminal region HEAT PF02985.17 EAU90073.2 - 1.8e-07 30.6 15.0 0.059 13.4 0.0 10.1 12 0 0 12 12 12 2 HEAT repeat Arm PF00514.18 EAU90073.2 - 7.1e-05 22.4 1.4 0.005 16.6 0.1 4.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EAU90073.2 - 0.0065 16.9 0.3 0.0065 16.9 0.2 7.4 7 2 2 9 9 9 1 HEAT-like repeat PTS_2-RNA PF01885.11 EAU90074.2 - 8.1e-39 132.8 0.0 1e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family MAGSP PF03082.9 EAU90074.2 - 0.013 14.8 0.1 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Male accessory gland secretory protein RTC4 PF14474.1 EAU90075.2 - 2.2e-23 82.5 0.0 5.1e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Flavin_Reduct PF01613.13 EAU90076.2 - 6.9e-26 90.9 0.1 1.4e-25 89.9 0.1 1.5 1 0 0 1 1 1 1 Flavin reductase like domain RabGAP-TBC PF00566.13 EAU90080.2 - 1.3e-45 155.4 0.0 2.2e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.27 EAU90080.2 - 0.00023 20.2 0.1 0.00087 18.4 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EAU90080.2 - 0.00026 20.6 0.1 0.0011 18.6 0.1 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EAU90080.2 - 0.00061 19.8 0.3 0.0028 17.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EAU90080.2 - 0.005 16.4 0.4 0.016 14.8 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain pair GRAM PF02893.15 EAU90080.2 - 0.0071 15.8 0.0 0.019 14.4 0.0 1.8 1 0 0 1 1 1 1 GRAM domain SPARC_Ca_bdg PF10591.4 EAU90080.2 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.27 EAU90081.2 - 2e-50 166.9 19.7 1.1e-10 40.9 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EAU90081.2 - 6.1e-07 29.3 0.2 0.00019 21.2 0.1 3.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAU90081.2 - 2.2e-05 22.7 9.1 0.047 11.8 0.6 4.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Pectate_lyase22 PF14583.1 EAU90081.2 - 0.018 13.4 0.0 0.044 12.2 0.0 1.6 2 0 0 2 2 2 0 Oligogalacturonate lyase RicinB_lectin_2 PF14200.1 EAU90081.2 - 0.1 12.9 0.1 2.1 8.7 0.0 2.7 1 1 2 3 3 3 0 Ricin-type beta-trefoil lectin domain-like TEA PF01285.13 EAU90082.2 - 1.1e-13 51.2 0.1 1.5e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 TEA/ATTS domain family Tmemb_170 PF10190.4 EAU90083.2 - 0.057 13.4 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative transmembrane protein 170 FtsX PF02687.16 EAU90083.2 - 0.33 10.7 8.7 0.13 12.0 3.6 1.9 2 0 0 2 2 2 0 FtsX-like permease family MMR_HSR1 PF01926.18 EAU90084.2 - 8.4e-15 54.7 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU90084.2 - 5.1e-06 26.4 0.0 9.6e-05 22.2 0.0 2.1 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.11 EAU90084.2 - 0.00039 19.6 0.0 0.0012 18.0 0.0 1.7 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.13 EAU90084.2 - 0.0032 16.7 0.0 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 EAU90084.2 - 0.012 15.0 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EAU90084.2 - 0.018 14.0 0.0 0.55 9.2 0.0 2.3 1 1 0 1 1 1 0 Septin DUF258 PF03193.11 EAU90084.2 - 0.034 13.3 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EAU90084.2 - 0.063 12.7 0.1 0.8 9.1 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Peptidase_M43 PF05572.8 EAU90085.2 - 1.4e-16 60.4 0.0 2.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EAU90085.2 - 3.4e-06 27.6 0.1 1.2e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU90085.2 - 9e-06 25.7 0.0 2.9e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAU90085.2 - 3.4e-05 23.9 0.0 5.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU90085.2 - 0.00015 21.3 0.1 0.00022 20.8 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU90085.2 - 0.013 15.1 0.1 0.02 14.6 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M57 PF12388.3 EAU90085.2 - 0.063 12.6 0.7 0.29 10.4 0.5 2.0 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Imm44 PF15584.1 EAU90085.2 - 0.073 12.9 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 44 DUF383 PF04063.9 EAU90089.1 - 7.7e-58 195.2 0.0 1.9e-57 193.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EAU90089.1 - 4.1e-17 61.5 0.6 8.3e-17 60.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Hydrophobin PF01185.13 EAU90090.1 - 3.3e-24 85.1 6.0 4.4e-24 84.7 4.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin R_equi_Vir PF05526.6 EAU90090.1 - 0.015 14.9 0.6 0.02 14.5 0.3 1.3 1 1 0 1 1 1 0 Rhodococcus equi virulence-associated protein Toxin_9 PF02819.10 EAU90090.1 - 6.6 6.8 8.4 0.95 9.5 0.7 2.3 2 0 0 2 2 2 0 Spider toxin p450 PF00067.17 EAU90091.1 - 1.7e-78 264.2 0.0 2e-78 263.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AICARFT_IMPCHas PF01808.13 EAU90092.1 - 1.6e-111 372.3 0.0 2.1e-111 372.0 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EAU90092.1 - 8.6e-23 80.0 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.1 EAU90093.2 - 4.4e-39 133.8 0.2 5.9e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EAU90093.2 - 1.6e-06 28.1 0.1 2.6e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 HD domain PX PF00787.19 EAU90095.1 - 9.4e-23 80.1 0.6 2.7e-22 78.6 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EAU90095.1 - 1.5e-06 27.6 6.9 0.0068 15.6 0.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EAU90095.1 - 0.0042 16.6 1.7 0.0042 16.6 1.2 2.2 2 0 0 2 2 2 1 BAR domain DUF4391 PF14335.1 EAU90095.1 - 0.013 14.8 1.5 0.026 13.8 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) GreA_GreB_N PF03449.10 EAU90095.1 - 0.023 14.7 1.0 0.023 14.7 0.7 3.0 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal DUF2924 PF11149.3 EAU90095.1 - 0.087 12.8 0.7 0.26 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) TPR_MLP1_2 PF07926.7 EAU90095.1 - 3.4 7.4 11.3 3.9 7.2 3.3 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein ETX_MTX2 PF03318.8 EAU90096.2 - 3.6e-09 36.5 7.9 4.9e-09 36.0 5.5 1.1 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 EAU90096.2 - 4.3e-07 29.1 2.4 5.9e-07 28.7 1.6 1.1 1 0 0 1 1 1 1 Aerolysin toxin Ank_2 PF12796.2 EAU90097.2 - 4.4e-22 78.2 0.3 1.2e-10 41.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90097.2 - 3.7e-19 67.4 9.9 0.00049 19.7 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EAU90097.2 - 7.4e-19 67.7 3.6 2.3e-07 31.1 0.1 4.8 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90097.2 - 1.8e-16 59.7 5.3 5.6e-09 35.9 0.1 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90097.2 - 3.5e-11 42.2 3.4 0.47 10.8 0.0 6.3 5 0 0 5 5 5 4 Ankyrin repeat TMCO5 PF14992.1 EAU90107.1 - 0.087 11.9 0.3 0.18 10.8 0.2 1.5 1 0 0 1 1 1 0 TMCO5 family Velvet PF11754.3 EAU90108.2 - 4.4e-15 55.8 0.0 5.6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Smr PF01713.16 EAU90111.1 - 2.3e-13 50.1 0.0 6.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Smr domain Acetyltransf_10 PF13673.1 EAU90111.1 - 0.00015 21.8 0.0 0.00042 20.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1771 PF08590.5 EAU90111.1 - 0.0023 17.9 5.6 0.019 14.9 3.3 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Acetyltransf_7 PF13508.1 EAU90111.1 - 0.0045 17.1 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2015 PF09435.5 EAU90112.1 - 9.8e-36 122.3 0.1 1.1e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Sds3 PF08598.6 EAU90114.2 - 7e-09 35.5 2.9 1e-08 34.9 2.0 1.4 1 1 0 1 1 1 1 Sds3-like DLH PF01738.13 EAU90115.1 - 4.2e-15 55.6 0.0 1.5e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU90115.1 - 0.0042 16.8 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_72 PF03198.9 EAU90116.1 - 2.7e-97 325.5 0.0 4.3e-97 324.8 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EAU90116.1 - 1.4e-18 67.1 0.4 1.4e-18 67.1 0.3 2.0 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.13 EAU90116.1 - 4.5e-05 22.8 0.1 0.00021 20.6 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EAU90116.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain CD99L2 PF12301.3 EAU90116.1 - 0.27 10.9 3.8 0.47 10.1 2.6 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF2183 PF09949.4 EAU90117.2 - 3.3e-25 87.9 0.0 6e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EAU90117.2 - 0.028 13.9 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) p450 PF00067.17 EAU90118.2 - 1.7e-55 188.3 0.0 2.5e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GATA PF00320.22 EAU90119.2 - 2.5e-14 52.2 2.2 2.5e-14 52.2 1.5 1.9 2 0 0 2 2 2 1 GATA zinc finger SnoaL_2 PF12680.2 EAU90122.1 - 0.00053 20.3 0.0 0.00097 19.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain Clathrin PF00637.15 EAU90123.2 - 4.2e-209 684.5 32.9 7e-33 113.2 0.0 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EAU90123.2 - 1.6e-34 115.8 4.6 3.2e-05 23.9 0.0 8.0 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 EAU90123.2 - 4.2e-30 103.4 0.1 1.8e-29 101.4 0.1 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 EAU90123.2 - 1.3e-10 40.0 1.2 2.5e-10 39.1 0.1 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_14 PF13428.1 EAU90123.2 - 0.11 13.1 15.0 0.63 10.8 0.2 7.6 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90123.2 - 0.14 11.8 4.2 11 5.7 0.1 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU90123.2 - 0.17 11.8 10.9 19 5.3 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAU90123.2 - 0.63 9.9 10.8 27 4.8 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU90123.2 - 4.1 7.4 17.2 1.8 8.5 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90123.2 - 9.2 6.4 10.6 49 4.2 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PQ-loop PF04193.9 EAU90124.2 - 3.7e-20 71.2 4.4 3.8e-15 55.1 0.5 3.1 3 0 0 3 3 3 2 PQ loop repeat UAA PF08449.6 EAU90125.2 - 9.8e-16 57.5 10.6 9.8e-16 57.5 7.3 1.4 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 EAU90125.2 - 2.9e-10 39.9 1.8 2.9e-10 39.9 1.2 2.6 2 1 2 4 4 4 1 Triose-phosphate Transporter family EamA PF00892.15 EAU90125.2 - 0.00034 20.6 17.6 0.0012 18.8 3.0 2.5 2 0 0 2 2 2 2 EamA-like transporter family CPSase_L_D2 PF02786.12 EAU90126.2 - 2e-80 269.0 0.2 3.5e-80 268.2 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EAU90126.2 - 9.2e-68 227.5 0.0 1.9e-67 226.5 0.0 1.6 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.14 EAU90126.2 - 1.7e-32 112.9 0.0 3.9e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_carb_C PF02785.14 EAU90126.2 - 3.7e-30 104.0 0.0 1.1e-29 102.4 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EAU90126.2 - 1.5e-19 70.4 0.2 2.8e-19 69.5 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EAU90126.2 - 5.8e-19 67.5 6.2 1.3e-18 66.3 3.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme CPSase_L_chain PF00289.17 EAU90126.2 - 9.1e-19 67.5 0.2 6e-18 64.9 0.1 2.4 2 1 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EAU90126.2 - 5.4e-16 58.2 0.0 4.4e-15 55.2 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EAU90126.2 - 1.3e-11 43.9 9.9 6.5e-06 25.7 0.5 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EAU90126.2 - 1.3e-11 44.2 0.0 2.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 EAU90126.2 - 2.2e-08 33.7 5.1 0.00033 20.0 0.2 2.6 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 EAU90126.2 - 4.7e-08 33.3 0.9 0.016 15.5 0.1 3.3 3 0 0 3 3 3 2 HlyD family secretion protein ATP-grasp PF02222.17 EAU90126.2 - 7.4e-08 31.9 0.1 1.5e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EAU90126.2 - 1.7e-05 24.7 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EAU90126.2 - 3.1e-05 23.5 0.0 6.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EAU90126.2 - 8.1e-05 21.9 1.0 0.19 10.8 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 EAU90126.2 - 0.00023 20.8 3.0 0.001 18.7 0.5 3.2 3 1 0 4 4 4 1 Glycine cleavage H-protein NQRA PF05896.6 EAU90126.2 - 0.00088 18.5 0.4 0.0022 17.2 0.3 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.1 EAU90126.2 - 0.0044 16.7 2.4 0.013 15.1 0.8 2.3 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain GARS_A PF01071.14 EAU90126.2 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.4 EAU90126.2 - 0.081 12.6 0.4 0.23 11.1 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Peptidase_M23 PF01551.17 EAU90126.2 - 0.083 12.9 0.6 2.3 8.3 0.4 3.0 1 1 0 1 1 1 0 Peptidase family M23 NMO PF03060.10 EAU90127.2 - 1.6e-47 162.3 3.2 2.4e-31 109.1 0.1 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EAU90127.2 - 0.001 18.0 0.8 0.0094 14.8 0.6 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase GSH-S_ATP PF02955.11 EAU90127.2 - 0.055 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain LSM PF01423.17 EAU90128.1 - 6.3e-16 57.6 0.0 8.2e-16 57.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ecl1 PF12855.2 EAU90129.1 - 0.013 14.7 1.3 0.022 14.0 0.2 1.9 2 0 0 2 2 2 0 Life-span regulatory factor SHR3_chaperone PF08229.6 EAU90130.1 - 1.6e-31 108.7 0.1 2e-31 108.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 RhoGAP PF00620.22 EAU90131.2 - 3.7e-42 143.5 0.0 5.9e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EAU90131.2 - 5.1e-12 45.9 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.19 EAU90131.2 - 1.2e-08 34.7 0.0 2.3e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 EAU90131.2 - 1.7e-07 31.4 0.0 3.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EAU90131.2 - 0.0069 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_7 PF15408.1 EAU90131.2 - 0.14 12.0 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain SGT1 PF07093.6 EAU90131.2 - 0.39 9.0 8.3 0.072 11.4 3.0 1.6 2 0 0 2 2 2 0 SGT1 protein Di19_C PF14571.1 EAU90131.2 - 0.56 10.5 7.1 2.2 8.6 2.8 3.1 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal DUF3498 PF12004.3 EAU90139.2 - 0.029 13.5 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) RhoGAP PF00620.22 EAU90142.2 - 3.2e-31 107.9 0.0 6.5e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EAU90142.2 - 2.4e-25 88.3 35.5 1.8e-10 40.6 6.0 4.4 4 0 0 4 4 4 4 LIM domain ParA PF10609.4 EAU90143.1 - 1.5e-36 124.0 0.0 2.6e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EAU90143.1 - 2.3e-13 50.0 0.0 3.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EAU90143.1 - 3.4e-05 23.0 0.3 0.0022 17.0 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EAU90143.1 - 0.00036 20.0 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EAU90143.1 - 0.0026 17.6 0.0 0.0062 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAU90143.1 - 0.024 13.8 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 EAU90143.1 - 0.039 13.1 0.0 1.1 8.3 0.0 2.5 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YjeF_N PF03853.10 EAU90143.1 - 0.06 12.9 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus YhjQ PF06564.7 EAU90143.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 YhjQ protein VirE PF05272.6 EAU90143.1 - 0.091 12.2 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_29 PF13555.1 EAU90143.1 - 0.14 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 EAU90144.2 - 5.4e-52 175.4 0.0 7e-52 175.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU90144.2 - 1.2e-15 58.0 0.0 1.6e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU90144.2 - 1.7e-08 33.9 0.0 2e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU90144.2 - 0.00044 19.4 0.0 0.00056 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAU90144.2 - 0.0036 16.5 0.0 0.0046 16.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAU90144.2 - 0.004 17.0 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.13 EAU90144.2 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Fungal_trans PF04082.13 EAU90145.2 - 9e-17 60.8 0.3 2.1e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syntaxin-6_N PF09177.6 EAU90145.2 - 0.27 11.6 1.8 1.4 9.3 0.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 EAU90146.2 - 0.00072 19.2 14.1 0.004 16.7 4.3 2.2 2 0 0 2 2 2 2 IncA protein FH2 PF02181.18 EAU90146.2 - 0.034 13.0 0.1 0.034 13.0 0.1 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain ATG16 PF08614.6 EAU90146.2 - 0.12 12.1 18.5 0.1 12.4 6.5 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ATG_C PF09333.6 EAU90146.2 - 0.18 11.9 1.3 3.8 7.7 0.0 2.6 2 1 0 2 2 2 0 ATG C terminal domain Spc7 PF08317.6 EAU90146.2 - 0.21 10.2 13.1 0.14 10.7 0.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein VASP_tetra PF08776.6 EAU90146.2 - 0.29 10.4 6.0 0.26 10.6 2.8 1.9 2 0 0 2 2 2 0 VASP tetramerisation domain Reo_sigmaC PF04582.7 EAU90146.2 - 0.59 9.2 10.0 0.76 8.9 1.0 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein CHASE3 PF05227.8 EAU90146.2 - 0.75 9.4 13.9 0.077 12.6 4.8 2.3 2 0 0 2 2 2 0 CHASE3 domain Acetyltransf_11 PF13720.1 EAU90146.2 - 1.9 8.7 3.7 6.3 7.0 0.3 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Phlebovirus_NSM PF07246.6 EAU90146.2 - 2.3 7.2 6.3 8.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Rootletin PF15035.1 EAU90146.2 - 2.4 8.0 21.2 0.8 9.6 8.1 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3584 PF12128.3 EAU90146.2 - 2.4 5.3 13.4 1.7 5.8 5.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4201 PF13870.1 EAU90146.2 - 3.6 6.9 20.3 2.6 7.4 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Sec8_exocyst PF04048.9 EAU90146.2 - 4.3 6.9 9.0 4.9 6.7 0.3 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain AAA_13 PF13166.1 EAU90146.2 - 4.5 5.6 7.4 5 5.4 0.6 2.0 2 0 0 2 2 2 0 AAA domain APG6 PF04111.7 EAU90146.2 - 4.6 6.1 15.8 3.2 6.7 4.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Uds1 PF15456.1 EAU90146.2 - 5.6 6.9 16.7 0.95 9.4 0.8 2.5 2 0 0 2 2 2 0 Up-regulated During Septation DivIVA PF05103.8 EAU90146.2 - 6 6.9 13.2 0.33 11.0 0.8 2.4 2 0 0 2 2 2 0 DivIVA protein Atg14 PF10186.4 EAU90146.2 - 8 5.3 13.2 11 4.8 0.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MscL PF01741.13 EAU90147.2 - 7.2e-14 52.0 0.1 1.5e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL UPF0547 PF10571.4 EAU90147.2 - 0.0046 16.6 3.4 0.008 15.8 2.4 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.2 EAU90147.2 - 0.025 14.3 0.3 0.04 13.7 0.2 1.2 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EAU90147.2 - 0.073 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain E6 PF00518.12 EAU90147.2 - 0.12 12.7 1.5 0.52 10.6 1.0 2.0 1 1 0 1 1 1 0 Early Protein (E6) DUF4383 PF14325.1 EAU90147.2 - 0.29 11.1 2.7 0.8 9.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) zf-BED PF02892.10 EAU90147.2 - 0.29 10.9 3.4 0.2 11.4 1.1 1.8 2 1 0 2 2 2 0 BED zinc finger zf-C3HC4_3 PF13920.1 EAU90147.2 - 1.1 8.9 5.6 1.5 8.5 0.3 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1771 PF08590.5 EAU90148.1 - 8e-14 51.4 8.4 1.5e-13 50.5 5.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EAU90148.1 - 1.9e-07 30.6 6.6 0.00016 21.2 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 EAU90148.1 - 0.00045 20.3 0.1 0.0013 18.8 0.1 1.8 1 0 0 1 1 1 1 Smr domain zf-C3H1 PF10650.4 EAU90148.1 - 0.048 13.1 1.8 1.3 8.5 0.2 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain Tom37_C PF11801.3 EAU90148.1 - 0.2 11.4 0.1 0.43 10.4 0.1 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain zf-CDGSH PF09360.5 EAU90149.2 - 1.4 8.8 4.8 7.2 6.5 0.1 2.7 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type Ank_5 PF13857.1 EAU90151.1 - 0.00057 20.0 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EAU90151.1 - 0.00087 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EAU90151.1 - 0.00091 19.2 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EAU90151.1 - 0.007 16.6 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU90151.1 - 0.0072 16.8 0.0 0.017 15.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PMM PF03332.8 EAU90152.1 - 8.1e-107 355.8 0.4 9.5e-107 355.5 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EAU90152.1 - 2.5e-05 23.9 0.0 0.00015 21.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU90152.1 - 0.08 13.3 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU90152.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PMM PF03332.8 EAU90153.2 - 3.3e-12 46.4 0.0 4.1e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase DNA_pol_B PF00136.16 EAU90154.1 - 2.3e-144 481.6 0.2 3.4e-144 481.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EAU90154.1 - 3.9e-78 262.5 0.0 8.3e-78 261.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EAU90154.1 - 2.1e-22 78.8 8.9 5.2e-22 77.6 6.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EAU90154.1 - 0.0011 18.7 0.1 0.0046 16.7 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EAU90154.1 - 0.0017 17.9 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.15 EAU90154.1 - 0.025 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease DNA_pol_B_2 PF03175.8 EAU90154.1 - 0.059 12.0 2.9 0.075 11.6 1.0 1.9 2 1 0 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.17 EAU90154.1 - 3.1 7.5 11.6 6.9 6.4 0.6 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SET PF00856.23 EAU90155.1 - 8.6e-07 29.3 0.0 8.8e-06 26.1 0.0 2.3 2 1 0 2 2 2 1 SET domain DUF1965 PF09248.5 EAU90155.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Ribosomal_L7Ae PF01248.21 EAU90156.1 - 5.7e-23 80.2 0.0 6.6e-23 80.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Prenyltrans_2 PF13249.1 EAU90157.2 - 2.1e-37 128.0 7.0 9.3e-14 51.7 0.1 5.6 3 1 3 6 6 6 5 Prenyltransferase-like Prenyltrans PF00432.16 EAU90157.2 - 7e-36 121.4 2.5 8.8e-11 41.1 0.1 6.7 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EAU90157.2 - 3.9e-28 97.6 4.5 2.2e-09 37.3 0.1 6.3 3 3 2 6 6 6 6 Prenyltransferase-like Pec_lyase PF09492.5 EAU90157.2 - 2.3e-07 30.2 0.6 0.3 10.2 0.0 5.1 2 1 3 6 6 6 3 Pectic acid lyase Brix PF04427.13 EAU90158.2 - 7.1e-26 91.0 0.0 2.6e-24 85.9 0.0 2.1 2 0 0 2 2 2 2 Brix domain Actin PF00022.14 EAU90160.1 - 1.8e-41 141.8 0.0 2.7e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAU90160.1 - 0.0002 20.0 0.0 0.00058 18.5 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein Cnd2 PF05786.9 EAU90161.1 - 3.3e-153 511.9 4.4 4.8e-153 511.3 3.0 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Matrilin_ccoil PF10393.4 EAU90162.2 - 0.17 11.2 1.1 0.44 9.9 0.1 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin RmuC PF02646.11 EAU90162.2 - 0.43 9.3 8.0 0.74 8.5 1.5 2.2 2 0 0 2 2 2 0 RmuC family DUF3450 PF11932.3 EAU90162.2 - 0.43 9.8 10.6 0.15 11.3 4.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fungal_trans_2 PF11951.3 EAU90162.2 - 0.5 8.9 4.8 0.58 8.6 2.6 1.6 1 1 1 2 2 2 0 Fungal specific transcription factor domain Methyltransf_16 PF10294.4 EAU90163.2 - 1.2e-26 93.2 0.1 3.3e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EAU90163.2 - 0.097 12.3 0.0 0.42 10.3 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase domain FPN1 PF06963.7 EAU90164.2 - 6.7e-82 275.1 14.4 4.1e-57 193.4 4.4 3.0 1 1 2 3 3 3 3 Ferroportin1 (FPN1) ATG22 PF11700.3 EAU90164.2 - 0.00016 20.3 1.6 0.00017 20.2 0.3 1.4 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like DUF3595 PF12166.3 EAU90168.1 - 0.18 10.6 0.1 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DEAD PF00270.24 EAU90170.1 - 4.6e-39 133.6 0.1 6.9e-39 133.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU90170.1 - 6.4e-21 73.9 0.0 3.4e-11 42.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EAU90170.1 - 0.00076 19.3 0.4 0.0084 15.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 EAU90170.1 - 0.00079 17.5 2.0 0.0012 17.0 1.4 1.1 1 0 0 1 1 1 1 CDC45-like protein Apt1 PF10351.4 EAU90170.1 - 0.14 10.9 6.6 0.24 10.1 4.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glypican PF01153.14 EAU90170.1 - 0.87 8.1 3.3 1.3 7.4 2.3 1.2 1 0 0 1 1 1 0 Glypican Nop14 PF04147.7 EAU90170.1 - 5.3 4.8 17.7 0.17 9.7 8.0 1.5 2 0 0 2 2 2 0 Nop14-like family Mitofilin PF09731.4 EAU90170.1 - 7.1 5.1 13.9 0.53 8.8 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Striatin PF08232.7 EAU90171.2 - 0.025 14.9 0.5 0.025 14.9 0.4 1.7 2 0 0 2 2 2 0 Striatin family Peptidase_M20 PF01546.23 EAU90172.2 - 5.2e-26 91.3 0.0 1.1e-25 90.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAU90172.2 - 2.6e-14 52.9 0.1 4e-09 36.2 0.0 2.4 1 1 1 2 2 2 2 Peptidase dimerisation domain DRMBL PF07522.9 EAU90173.1 - 1.6e-30 105.3 0.0 3.4e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EAU90173.1 - 1.9e-09 37.3 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EAU90173.1 - 0.015 14.9 0.7 0.037 13.6 0.5 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Ribosomal_S4e PF00900.15 EAU90174.2 - 2.2e-30 104.1 0.3 5.6e-30 102.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EAU90174.2 - 1.1e-20 73.1 3.3 2.9e-20 71.8 2.2 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EAU90174.2 - 3.9e-08 32.5 0.0 8.4e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EAU90174.2 - 4e-06 26.3 3.6 1.4e-05 24.6 2.5 2.0 1 0 0 1 1 1 1 KOW motif Tox-ART-HYD1 PF15633.1 EAU90174.2 - 0.12 13.1 0.0 0.48 11.2 0.0 1.9 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase TPT PF03151.11 EAU90175.2 - 2.4e-32 111.6 3.6 2.4e-32 111.6 2.5 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EAU90175.2 - 3.9e-13 49.0 16.0 5.3e-13 48.5 11.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EAU90175.2 - 1.1e-10 41.6 32.5 3.6e-07 30.2 9.1 3.5 2 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EAU90175.2 - 0.0019 17.3 0.7 0.056 12.5 0.0 2.3 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF1576 PF07613.6 EAU90175.2 - 0.71 9.3 13.1 0.023 14.1 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) Multi_Drug_Res PF00893.14 EAU90175.2 - 3.2 8.2 11.4 1.2 9.6 0.6 3.5 2 1 1 3 3 3 0 Small Multidrug Resistance protein CRAL_TRIO PF00650.15 EAU90176.2 - 2.7e-27 95.1 0.0 4.3e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAU90176.2 - 0.00017 21.6 0.0 0.0006 19.8 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Paf1 PF03985.8 EAU90178.2 - 4.1e-58 197.1 0.1 5e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Paf1 SnoaL_2 PF12680.2 EAU90180.1 - 3.3e-06 27.4 0.0 4.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EAU90180.1 - 0.00014 21.4 0.1 0.00022 20.8 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase NTF2 PF02136.15 EAU90180.1 - 0.0047 17.2 0.0 0.0063 16.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain AAA_3 PF07726.6 EAU90180.1 - 0.028 13.9 0.0 0.068 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4440 PF14534.1 EAU90180.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Aminotran_5 PF00266.14 EAU90181.2 - 1.9e-21 76.2 0.0 1.1e-20 73.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V AATF-Che1 PF13339.1 EAU90182.2 - 2.5e-28 98.8 3.3 2.5e-28 98.8 2.3 3.0 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EAU90182.2 - 2.5e-26 91.6 0.9 5.9e-26 90.3 0.0 2.1 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal SDA1 PF05285.7 EAU90182.2 - 2.4 7.3 27.7 0.03 13.6 13.8 1.8 2 0 0 2 2 2 0 SDA1 Herpes_DNAp_acc PF04929.7 EAU90182.2 - 4.5 6.1 6.8 8.4 5.2 4.7 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.9 EAU90182.2 - 8 4.3 17.7 14 3.6 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C4H2 PF10146.4 EAU90183.2 - 1.2 9.1 5.5 0.13 12.2 0.7 1.7 2 1 0 2 2 2 0 Zinc finger-containing protein DNA_pol_B PF00136.16 EAU90184.2 - 5.5e-112 374.9 0.0 7.8e-112 374.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EAU90184.2 - 2.4e-60 203.1 0.6 3.9e-60 202.4 0.4 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EAU90184.2 - 5e-24 84.7 0.0 1.3e-23 83.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EAU90184.2 - 1.4e-18 66.4 7.1 5.5e-18 64.5 4.9 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Pirin PF02678.11 EAU90185.1 - 7.5e-25 86.8 0.9 1.2e-24 86.1 0.6 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EAU90185.1 - 1.9e-09 36.9 0.8 4.5e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EAU90185.1 - 0.05 12.9 0.3 0.72 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF4470 PF14737.1 EAU90186.1 - 2.6e-18 65.5 0.0 4.3e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) MFS_1 PF07690.11 EAU90189.2 - 4.3e-32 111.1 42.4 5.7e-30 104.2 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EAU90190.2 - 1.2e-32 113.0 24.2 1.6e-32 112.5 16.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Orbi_NS3 PF01616.11 EAU90190.2 - 0.19 10.6 0.0 1.3 7.9 0.0 2.0 2 0 0 2 2 2 0 Orbivirus NS3 SieB PF14163.1 EAU90190.2 - 0.4 10.2 0.0 0.4 10.2 0.0 2.9 4 0 0 4 4 4 0 Superinfection exclusion protein B DUF996 PF06195.8 EAU90190.2 - 1.8 8.5 9.2 3.2 7.7 2.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF996) DUF4212 PF13937.1 EAU90190.2 - 7.5 6.6 9.0 7.9 6.5 3.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) F-box PF00646.28 EAU90193.1 - 2.2e-05 23.9 1.2 6.2e-05 22.5 0.8 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU90193.1 - 4.7e-05 23.0 0.9 0.00015 21.3 0.6 1.9 1 0 0 1 1 1 1 F-box-like Hydrophobin PF01185.13 EAU90194.1 - 6.8e-22 77.7 7.2 9.2e-22 77.2 5.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 EAU90194.1 - 1.6 9.3 8.3 4.2 7.9 0.5 2.8 3 0 0 3 3 3 0 Ion channel inhibitory toxin TPR_11 PF13414.1 EAU90198.1 - 5.8e-21 73.9 4.8 6.3e-12 44.9 0.2 3.7 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 EAU90198.1 - 1.7e-13 50.8 3.5 1.1e-08 35.5 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90198.1 - 2.1e-13 49.0 5.3 2.7e-07 29.9 0.1 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90198.1 - 3.1e-13 48.7 2.7 3.4e-08 32.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU90198.1 - 1.5e-12 47.2 3.5 5.2e-06 26.2 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAU90198.1 - 2.3e-12 46.0 0.7 0.0024 17.9 0.1 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAU90198.1 - 3.1e-11 43.4 2.0 0.00015 21.9 0.2 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU90198.1 - 4.5e-08 33.0 3.7 0.00025 21.3 0.0 4.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU90198.1 - 2.1e-07 30.2 2.7 0.00027 20.4 0.1 4.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EAU90198.1 - 1.1e-06 27.9 0.2 1.5e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAU90198.1 - 4.1e-06 26.5 0.2 0.027 14.3 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU90198.1 - 5.9e-06 25.6 6.1 0.0032 17.1 0.0 4.3 3 2 2 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU90198.1 - 3.1e-05 24.0 0.5 0.0026 17.8 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EAU90198.1 - 7.6e-05 22.9 1.7 0.023 15.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EAU90198.1 - 0.00014 21.6 6.2 0.67 9.8 0.1 3.3 2 1 1 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EAU90198.1 - 0.0002 21.1 6.9 0.11 12.4 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 EAU90198.1 - 0.00098 18.8 2.0 0.57 10.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EAU90198.1 - 0.0092 16.0 0.8 0.4 10.8 0.1 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 EAU90198.1 - 0.011 15.7 0.6 0.28 11.2 0.0 2.6 2 1 0 2 2 2 0 Tetratrico peptide repeat Apc5 PF12862.2 EAU90198.1 - 0.011 15.4 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.2 EAU90198.1 - 0.02 14.7 0.6 0.54 10.0 0.0 2.5 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.9 EAU90198.1 - 0.032 14.6 4.3 1.7 9.2 0.1 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF4175 PF13779.1 EAU90198.1 - 0.062 10.9 0.1 0.12 10.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Tim17 PF02466.14 EAU90199.1 - 8.2e-25 87.3 4.9 1e-24 87.0 3.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Hydrophobin PF01185.13 EAU90201.1 - 3.1e-21 75.6 5.6 4.4e-21 75.1 3.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Y_phosphatase2 PF03162.8 EAU90202.1 - 0.066 12.5 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Mus7 PF09462.5 EAU90203.1 - 8.3e-35 120.7 0.1 4.8e-30 104.9 0.1 2.2 2 0 0 2 2 2 2 Mus7/MMS22 family Cytochrom_C1 PF02167.10 EAU90205.1 - 8.2e-86 287.1 0.0 1e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EAU90205.1 - 0.00083 19.4 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EAU90205.1 - 0.0094 16.7 0.3 0.025 15.4 0.1 1.9 2 1 0 2 2 2 1 Cytochrome c SAC3_GANP PF03399.11 EAU90206.1 - 7e-59 198.8 2.1 1.3e-58 197.9 1.5 1.5 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EAU90206.1 - 4e-07 29.9 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 tRNA_int_endo PF01974.12 EAU90207.2 - 1.2e-19 69.8 0.9 3.3e-19 68.4 0.6 1.7 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EAU90207.2 - 0.0003 20.2 0.0 0.022 14.3 0.0 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain WD40 PF00400.27 EAU90208.2 - 1.1e-16 59.9 8.4 2.2e-06 27.3 0.1 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat HAND PF09110.6 EAU90208.2 - 0.19 12.1 6.0 0.59 10.5 4.2 1.8 1 0 0 1 1 1 0 HAND Viral_coat PF00729.13 EAU90209.1 - 0.013 14.7 0.7 0.019 14.2 0.5 1.2 1 0 0 1 1 1 0 Viral coat protein (S domain) Rhomboid PF01694.17 EAU90212.2 - 5.3e-15 55.7 15.9 1.9e-13 50.6 11.0 2.8 1 1 0 1 1 1 1 Rhomboid family zf-C3HC4 PF00097.20 EAU90213.2 - 1.4e-08 34.2 5.3 3e-08 33.1 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU90213.2 - 5.1e-08 32.4 4.5 1e-07 31.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU90213.2 - 1.1e-07 31.5 5.2 2.4e-07 30.4 3.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAU90213.2 - 1.9e-07 30.7 5.1 4.7e-07 29.4 3.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH PF00642.19 EAU90213.2 - 4.4e-06 26.2 12.0 0.00025 20.6 2.1 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EAU90213.2 - 4.5e-06 26.5 6.4 4.5e-06 26.5 4.4 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAU90213.2 - 0.0013 18.8 1.1 0.0031 17.5 0.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EAU90213.2 - 0.014 15.1 2.1 0.032 13.9 1.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAU90213.2 - 0.033 14.0 7.0 0.21 11.5 4.9 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EAU90213.2 - 0.3 10.9 6.8 2 8.2 4.7 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EAU90213.2 - 0.91 9.4 5.3 0.18 11.6 0.8 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Methyltransf_16 PF10294.4 EAU90214.2 - 1.9e-26 92.5 0.0 2.9e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EAU90214.2 - 5.9e-05 22.8 0.0 8.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU90214.2 - 0.003 18.1 0.0 0.0054 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EAU90214.2 - 0.012 14.6 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EAU90214.2 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EAU90214.2 - 0.039 13.3 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EAU90214.2 - 0.045 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EAU90214.2 - 0.069 13.6 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EAU90214.2 - 0.073 12.6 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Asp PF00026.18 EAU90216.2 - 2.4e-63 214.3 2.1 1.1e-56 192.4 0.4 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAU90216.2 - 4.6e-06 26.6 0.2 1.5e-05 25.0 0.1 1.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EAU90216.2 - 0.11 12.0 0.1 0.65 9.5 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Histone PF00125.19 EAU90217.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU90217.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAU90217.1 - 0.00065 19.7 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EAU90217.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EAU90217.1 - 0.11 11.6 1.5 0.12 11.5 1.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EAU90218.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU90218.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EAU90218.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EAU90218.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EAU90218.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EAU90218.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF98 PF01947.11 EAU90219.2 - 0.14 11.8 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF98) SIR2 PF02146.12 EAU90220.2 - 2e-42 144.9 0.0 4.2e-32 111.3 0.0 2.2 1 1 1 2 2 2 2 Sir2 family DUF592 PF04574.8 EAU90220.2 - 1.6e-05 24.5 0.5 0.0002 20.9 0.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF592) Ribosomal_60s PF00428.14 EAU90220.2 - 0.018 15.4 0.0 0.094 13.1 0.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPP_enzyme_M PF00205.17 EAU90220.2 - 0.053 13.2 0.2 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TRH PF05438.7 EAU90220.2 - 0.067 12.5 1.8 0.13 11.6 0.1 2.3 3 0 0 3 3 3 0 Thyrotropin-releasing hormone (TRH) RNA_pol_Rpb2_2 PF04561.9 EAU90220.2 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 PTS_2-RNA PF01885.11 EAU90221.2 - 1e-07 31.4 0.0 1.5e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Arginosuc_synth PF00764.14 EAU90222.1 - 3.3e-152 507.0 0.0 4e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EAU90222.1 - 0.00021 20.6 0.0 0.00032 20.0 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EAU90222.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EAU90222.1 - 0.024 13.2 0.0 0.044 12.3 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase zf-C3HC4_3 PF13920.1 EAU90223.2 - 5.3e-09 35.6 6.3 9e-09 34.8 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU90223.2 - 1e-08 35.0 6.1 2.6e-08 33.7 4.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU90223.2 - 4.8e-08 32.7 8.6 9.4e-08 31.7 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EAU90223.2 - 8.8e-07 28.5 6.5 1.6e-06 27.7 4.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU90223.2 - 3.3e-06 26.6 6.9 6.5e-06 25.7 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU90223.2 - 6e-05 22.6 1.6 6e-05 22.6 1.1 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAU90223.2 - 0.0004 20.1 2.2 0.0004 20.1 1.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING IncA PF04156.9 EAU90223.2 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 IncA protein CENP-F_leu_zip PF10473.4 EAU90223.2 - 0.028 14.2 3.3 0.046 13.5 2.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 EAU90223.2 - 0.045 11.8 3.0 0.065 11.2 2.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Med9 PF07544.8 EAU90223.2 - 0.05 13.3 1.1 0.12 12.1 0.8 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Sec8_exocyst PF04048.9 EAU90223.2 - 0.093 12.3 1.8 0.16 11.5 1.3 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Tmpp129 PF10272.4 EAU90223.2 - 0.17 10.6 4.8 0.25 10.0 3.3 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Spc7 PF08317.6 EAU90223.2 - 0.19 10.3 4.3 0.29 9.7 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.1 EAU90223.2 - 0.2 11.6 4.3 0.33 10.8 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-RING_6 PF14835.1 EAU90223.2 - 0.58 9.9 5.1 0.15 11.8 0.3 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein TMPIT PF07851.8 EAU90223.2 - 0.96 8.4 2.0 1.5 7.8 1.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-rbx1 PF12678.2 EAU90223.2 - 1.6 8.9 7.9 12 6.0 5.5 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger Vps39_2 PF10367.4 EAU90223.2 - 5 7.3 6.9 1.1 9.4 1.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Prok-RING_4 PF14447.1 EAU90223.2 - 7.7 6.1 9.0 1.6 8.3 0.5 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Nucleopor_Nup85 PF07575.8 EAU90224.2 - 2.6e-55 187.7 0.0 1.9e-36 125.4 0.0 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin GGDEF PF00990.16 EAU90224.2 - 0.028 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 GGDEF domain RhoGAP PF00620.22 EAU90225.2 - 2.6e-47 160.2 0.0 5.6e-47 159.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EAU90225.2 - 5e-15 55.4 0.5 6.3e-14 51.9 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain ALMT PF11744.3 EAU90225.2 - 0.08 11.5 0.2 0.12 10.9 0.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DivIC PF04977.10 EAU90225.2 - 0.53 9.7 8.0 0.054 12.9 1.7 2.3 3 0 0 3 3 3 0 Septum formation initiator F-box-like PF12937.2 EAU90226.2 - 1.1e-05 25.0 0.2 3.9e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like Histone PF00125.19 EAU90227.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU90227.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EAU90227.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EAU90227.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EAU90227.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EAU90227.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EAU90228.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU90228.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAU90228.1 - 0.00065 19.7 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EAU90228.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EAU90228.1 - 0.11 11.6 1.5 0.12 11.5 1.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FA_hydroxylase PF04116.8 EAU90231.1 - 3.5e-19 69.2 10.8 3.5e-19 69.2 7.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Rcd1 PF04078.8 EAU90232.1 - 8.1e-129 428.0 3.1 9.3e-129 427.8 2.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like NIR_SIR PF01077.17 EAU90233.1 - 3.2e-50 169.5 0.0 7.5e-45 152.0 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EAU90233.1 - 7.4e-31 105.5 0.0 3.9e-14 52.0 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EAU90233.1 - 1.1e-28 100.0 0.0 1.9e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EAU90233.1 - 0.035 13.6 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 EAU90233.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Peripla_BP_6 PF13458.1 EAU90233.1 - 0.05 12.9 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Periplasmic binding protein DUF1295 PF06966.7 EAU90234.1 - 3.5e-52 177.0 2.3 5.1e-52 176.5 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EAU90234.1 - 0.00086 19.3 5.2 0.0012 18.8 0.0 3.1 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EAU90234.1 - 0.0016 18.5 1.4 0.0058 16.7 0.0 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EAU90234.1 - 0.013 15.2 2.6 0.072 12.8 0.0 2.9 3 0 0 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase PH PF00169.24 EAU90235.2 - 0.0027 17.8 0.2 0.01 16.0 0.1 2.0 1 0 0 1 1 1 1 PH domain SPX PF03105.14 EAU90235.2 - 0.0038 17.0 9.1 0.0052 16.5 6.3 1.4 1 0 0 1 1 1 1 SPX domain GMC_oxred_C PF05199.8 EAU90238.1 - 7.8e-17 61.8 0.0 1.4e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DUF3453 PF11935.3 EAU90241.2 - 3e-28 98.8 3.3 3.1e-13 49.6 0.1 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3453) Symplekin_C PF12295.3 EAU90241.2 - 5.5e-28 98.1 2.5 2.7e-27 95.8 0.1 2.9 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal SnoaL_2 PF12680.2 EAU90242.1 - 0.017 15.5 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Ribosomal_S19 PF00203.16 EAU90244.2 - 1.3e-33 114.4 0.2 2.1e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EAU90244.2 - 0.012 15.5 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH GIT_SHD PF08518.6 EAU90244.2 - 0.092 12.1 0.1 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Ribosomal_60s PF00428.14 EAU90245.2 - 7.3e-29 100.0 9.1 1e-28 99.5 6.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Fungal_trans PF04082.13 EAU90246.2 - 2.2e-19 69.3 1.3 3.5e-19 68.6 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU90246.2 - 2.2e-09 37.0 10.3 2.2e-09 37.0 7.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V-ATPase_G PF03179.10 EAU90247.1 - 1.3e-34 118.6 12.0 1.5e-34 118.4 8.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EAU90247.1 - 0.021 14.6 12.4 0.021 14.6 8.6 1.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DXP_synthase_N PF13292.1 EAU90247.1 - 0.075 11.9 0.1 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Nop25 PF09805.4 EAU90247.1 - 0.083 12.9 7.7 0.11 12.6 5.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3535 PF12054.3 EAU90247.1 - 0.4 9.2 3.8 0.47 9.0 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Seryl_tRNA_N PF02403.17 EAU90247.1 - 0.84 9.6 5.9 1.2 9.1 3.5 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PGBA_C PF15437.1 EAU90247.1 - 2.3 8.3 11.8 0.78 9.9 6.3 1.6 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal SnoaL_2 PF12680.2 EAU90250.1 - 0.047 14.0 0.8 0.077 13.4 0.5 1.6 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.1 EAU90250.1 - 0.076 12.9 0.1 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.2 EAU90252.2 - 0.0015 18.9 0.0 0.0024 18.2 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 EAU90252.2 - 0.0081 16.5 0.0 0.01 16.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Transposase_21 PF02992.9 EAU90253.2 - 7.2e-12 44.8 0.0 1.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EAU90253.2 - 0.026 13.9 0.0 0.085 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4218) SnoaL_2 PF12680.2 EAU90256.2 - 0.079 13.3 0.0 0.11 12.9 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.15 EAU90256.2 - 0.1 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Carn_acyltransf PF00755.15 EAU90258.2 - 1.5e-135 452.5 0.0 1.7e-135 452.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1972 PF09314.6 EAU90271.2 - 0.082 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) DUF4573 PF15140.1 EAU90284.2 - 0.078 12.5 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4573) FA_FANCE PF11510.3 EAU90285.2 - 0.11 11.5 0.3 0.97 8.5 0.3 1.9 1 1 1 2 2 2 0 Fanconi Anaemia group E protein FANCE Pkinase PF00069.20 EAU90286.2 - 1.7e-56 191.2 0.0 2.6e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU90286.2 - 7.4e-28 97.3 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU90286.2 - 5.3e-09 35.4 0.0 8.9e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU90286.2 - 0.0013 17.8 0.5 0.0058 15.7 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU90286.2 - 0.01 15.5 0.1 0.018 14.7 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EAU90286.2 - 0.04 13.2 0.2 0.084 12.2 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EAU90286.2 - 0.084 11.6 0.3 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Guanylate_kin PF00625.16 EAU90287.1 - 9.7e-65 217.4 0.0 1.3e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EAU90287.1 - 3.6e-10 40.1 0.0 7.8e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EAU90287.1 - 1.7e-08 34.4 0.1 7.5e-08 32.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU90287.1 - 3.2e-05 24.0 0.0 0.00013 22.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAU90287.1 - 0.00033 19.8 0.0 0.00061 19.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EAU90287.1 - 0.00036 20.8 0.0 0.00075 19.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU90287.1 - 0.00053 20.7 0.0 0.00098 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EAU90287.1 - 0.0013 18.8 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EAU90287.1 - 0.0038 17.1 0.0 0.0062 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAU90287.1 - 0.0044 16.7 0.0 0.021 14.5 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase MMR_HSR1 PF01926.18 EAU90287.1 - 0.0048 16.8 0.0 0.0076 16.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EAU90287.1 - 0.0071 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EAU90287.1 - 0.0074 16.5 0.0 0.0083 16.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter NACHT PF05729.7 EAU90287.1 - 0.0078 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 EAU90287.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAU90287.1 - 0.024 14.3 0.0 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EAU90287.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EAU90287.1 - 0.033 14.3 0.0 0.12 12.5 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.7 EAU90287.1 - 0.044 13.0 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein NTPase_1 PF03266.10 EAU90287.1 - 0.044 13.4 0.0 0.093 12.4 0.0 1.6 2 0 0 2 2 2 0 NTPase Miro PF08477.8 EAU90287.1 - 0.054 13.9 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Rad17 PF03215.10 EAU90287.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KAP_NTPase PF07693.9 EAU90287.1 - 0.17 10.8 0.8 1.2 8.0 0.6 2.0 1 1 0 1 1 1 0 KAP family P-loop domain ABC_membrane PF00664.18 EAU90288.2 - 3.3e-67 226.8 27.2 5.5e-41 140.7 4.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAU90288.2 - 8.8e-53 178.2 0.0 1.2e-30 106.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EAU90288.2 - 6.8e-07 28.7 0.0 0.0023 17.1 0.0 3.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EAU90288.2 - 9e-06 25.7 0.1 0.038 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EAU90288.2 - 2.7e-05 24.1 0.0 0.22 11.4 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase Miro PF08477.8 EAU90288.2 - 3.4e-05 24.3 0.3 0.32 11.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_21 PF13304.1 EAU90288.2 - 3.7e-05 23.8 0.3 1.1 9.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EAU90288.2 - 6.7e-05 22.3 0.2 0.085 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU90288.2 - 0.00038 20.8 0.1 1 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EAU90288.2 - 0.0016 17.9 0.1 1 8.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EAU90288.2 - 0.002 17.3 0.2 0.65 9.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 T2SE PF00437.15 EAU90288.2 - 0.0028 16.5 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 EAU90288.2 - 0.0039 17.0 0.3 1.1 9.0 0.0 2.8 3 0 0 3 3 2 1 Dynamin family Zeta_toxin PF06414.7 EAU90288.2 - 0.0097 15.0 0.8 0.89 8.6 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin FtsK_SpoIIIE PF01580.13 EAU90288.2 - 0.014 14.8 0.3 0.35 10.3 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.14 EAU90288.2 - 0.016 14.6 0.6 0.48 9.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EAU90288.2 - 0.019 14.7 0.0 0.94 9.1 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase DUF87 PF01935.12 EAU90288.2 - 0.019 14.7 5.6 0.62 9.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EAU90288.2 - 0.019 14.4 0.4 5.4 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_22 PF13401.1 EAU90288.2 - 0.055 13.6 2.1 12 6.1 0.3 3.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EAU90288.2 - 0.056 13.0 0.3 5.4 6.5 0.1 3.0 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 EAU90288.2 - 0.063 11.9 0.3 5.3 5.5 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ArgK PF03308.11 EAU90288.2 - 0.067 11.9 0.2 4.5 5.9 0.1 2.4 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 EAU90288.2 - 0.082 12.5 0.5 0.28 10.8 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EAU90288.2 - 0.19 12.5 0.4 12 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EAU90288.2 - 0.22 10.9 0.1 8.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain EMP24_GP25L PF01105.19 EAU90290.1 - 3.8e-51 173.4 0.1 4.6e-51 173.1 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2012 PF09430.5 EAU90290.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) GPI-anchored PF10342.4 EAU90292.1 - 0.00015 22.2 0.1 0.00021 21.7 0.1 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EAU90292.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3989 PF13150.1 EAU90292.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Mito_carr PF00153.22 EAU90293.1 - 2e-70 232.5 4.4 1.9e-23 81.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KduI PF04962.7 EAU90293.1 - 0.058 12.4 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 KduI/IolB family CBM_19 PF03427.8 EAU90294.1 - 0.081 12.7 8.6 0.19 11.5 4.3 2.3 1 1 1 2 2 2 0 Carbohydrate binding domain (family 19) TraO PF10626.4 EAU90294.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Conjugative transposon protein TraO PAT1 PF09770.4 EAU90295.2 - 4.5e-146 488.2 76.7 2.1e-126 423.2 4.8 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 hDGE_amylase PF14701.1 EAU90296.1 - 1.1e-163 545.0 0.0 1.5e-163 544.6 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EAU90296.1 - 4.8e-114 380.9 0.0 6.8e-114 380.4 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EAU90296.1 - 4.6e-82 275.0 0.0 9.5e-82 274.0 0.0 1.5 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EAU90296.1 - 4.2e-20 71.3 0.0 8.6e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EAU90296.1 - 0.00013 21.5 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Ank_2 PF12796.2 EAU90297.2 - 2e-67 223.5 10.7 6.6e-12 45.6 0.0 8.7 2 1 6 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90297.2 - 1.3e-62 204.6 18.4 1.7e-05 24.3 0.0 14.4 15 0 0 15 15 15 12 Ankyrin repeat Ank_5 PF13857.1 EAU90297.2 - 1.9e-51 170.8 18.3 7.5e-09 35.5 0.0 11.4 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU90297.2 - 1e-45 153.2 6.6 3.3e-08 33.8 0.0 10.3 6 5 6 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90297.2 - 5.2e-45 146.9 0.4 0.0013 18.7 0.0 13.5 14 0 0 14 14 14 11 Ankyrin repeat NB-ARC PF00931.17 EAU90297.2 - 0.00022 20.1 0.0 0.00037 19.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EAU90297.2 - 0.0084 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain HHH PF00633.18 EAU90297.2 - 2.5 7.9 4.8 17 5.3 0.0 4.2 5 0 0 5 5 5 0 Helix-hairpin-helix motif DUF914 PF06027.7 EAU90298.2 - 5e-100 334.6 8.1 6.2e-100 334.3 5.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EAU90298.2 - 0.56 10.2 30.8 1.5 8.8 5.9 3.2 2 1 1 3 3 3 0 EamA-like transporter family Zip PF02535.17 EAU90298.2 - 0.62 9.0 7.2 1.1 8.2 0.2 2.5 3 0 0 3 3 3 0 ZIP Zinc transporter Pribosyltran PF00156.22 EAU90300.1 - 7.5e-07 28.9 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FliG_C PF01706.11 EAU90300.1 - 0.12 12.3 0.0 21 5.1 0.0 2.2 2 0 0 2 2 2 0 FliG C-terminal domain RNA_pol_Rpc4 PF05132.9 EAU90301.1 - 6.1e-20 71.5 0.0 6.5e-18 64.9 0.0 3.5 3 1 0 3 3 3 1 RNA polymerase III RPC4 Fungal_trans PF04082.13 EAU90302.2 - 3.1e-05 23.0 1.7 0.027 13.3 0.0 2.9 2 1 2 4 4 4 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU90302.2 - 0.00017 21.4 12.7 0.00037 20.3 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF641 PF04859.7 EAU90302.2 - 0.079 12.7 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TFIID_30kDa PF03540.8 EAU90303.1 - 1.8e-27 94.8 0.1 4.5e-27 93.6 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.8 EAU90303.1 - 0.0037 16.9 0.0 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 Bromodomain associated FoP_duplication PF13865.1 EAU90303.1 - 0.036 14.4 0.4 0.72 10.3 0.1 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 FAD_binding_3 PF01494.14 EAU90304.2 - 1.9e-18 66.6 0.0 4.3e-18 65.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAU90304.2 - 1e-06 27.9 0.0 0.016 14.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU90304.2 - 0.00032 20.6 0.1 0.00084 19.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EAU90304.2 - 0.00072 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU90304.2 - 0.002 16.6 0.1 0.0099 14.3 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EAU90304.2 - 0.02 15.2 0.4 3 8.3 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_2 PF13639.1 EAU90305.2 - 4.1e-08 32.9 5.9 4.1e-08 32.9 4.1 4.8 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EAU90305.2 - 4.2e-08 32.7 4.5 4.2e-08 32.7 3.1 6.7 4 3 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90305.2 - 1.8e-05 24.3 5.8 1.8e-05 24.3 4.0 4.6 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAU90305.2 - 6e-05 22.9 6.3 6e-05 22.9 4.3 6.5 5 3 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EAU90305.2 - 8e-05 22.4 11.0 8e-05 22.4 7.6 4.3 2 2 1 3 3 3 1 IBR domain DUF484 PF04340.7 EAU90305.2 - 0.078 12.4 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Zip PF02535.17 EAU90307.1 - 2.6e-51 174.5 10.5 2.6e-51 174.5 7.3 2.0 1 1 1 2 2 2 1 ZIP Zinc transporter Brix PF04427.13 EAU90309.2 - 1.4e-32 112.8 0.0 1.3e-30 106.4 0.0 2.3 1 1 0 1 1 1 1 Brix domain DUF4604 PF15377.1 EAU90310.2 - 2.5e-25 89.5 21.1 2.5e-25 89.5 14.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Herpes_capsid PF06112.6 EAU90310.2 - 0.32 11.0 7.8 0.45 10.5 5.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Methyltransf_11 PF08241.7 EAU90311.1 - 3.1e-13 50.0 0.0 6.7e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU90311.1 - 8.1e-11 41.7 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU90311.1 - 1.8e-10 41.4 0.0 2.5e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU90311.1 - 1.2e-07 31.9 0.0 2.6e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU90311.1 - 5.3e-06 26.2 0.0 1.5e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU90311.1 - 2.5e-05 23.5 0.2 0.068 12.2 0.1 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EAU90311.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EAU90311.1 - 0.025 13.4 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.7 EAU90311.1 - 0.045 13.1 0.1 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.6 EAU90311.1 - 0.058 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 EAU90311.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EAU90311.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_28 PF02636.12 EAU90312.2 - 1.1e-37 129.7 0.0 1.7e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 EAU90312.2 - 0.0025 18.2 0.0 0.0094 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU90312.2 - 0.0037 17.6 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EAU90312.2 - 0.0095 14.9 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PRMT5 PF05185.11 EAU90312.2 - 0.063 12.1 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase MMS19_C PF12460.3 EAU90313.2 - 2.4e-102 342.7 4.9 2.4e-102 342.7 3.4 1.8 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EAU90313.2 - 6.1e-93 310.8 0.0 7.2e-90 300.7 0.0 4.0 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EAU90313.2 - 2.7e-09 37.1 1.6 0.0025 18.0 0.0 6.1 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EAU90313.2 - 1.4e-05 25.4 4.2 0.16 12.5 0.0 6.5 6 2 1 7 7 7 2 HEAT-like repeat HEAT PF02985.17 EAU90313.2 - 1.8e-05 24.4 0.7 6.3 7.1 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.3 EAU90313.2 - 0.02 14.2 0.0 0.36 10.1 0.0 3.2 2 1 1 3 3 3 0 CLASP N terminal DUF1546 PF07571.8 EAU90313.2 - 0.021 14.9 0.5 3 8.0 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1546) SCA7 PF08313.7 EAU90315.1 - 2.6e-28 97.4 0.1 2.6e-28 97.4 0.1 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain DSBA PF01323.15 EAU90315.1 - 4.4 6.8 6.1 16 4.9 2.9 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain FF PF01846.14 EAU90316.2 - 2.4e-38 129.8 6.7 4.8e-14 52.0 0.1 6.1 5 1 1 6 6 6 5 FF domain WW PF00397.21 EAU90316.2 - 2.3e-15 56.1 14.4 1.2e-08 34.6 1.8 2.9 2 0 0 2 2 2 2 WW domain Ribosomal_L21p PF00829.16 EAU90317.1 - 1e-12 47.9 0.5 1.2e-12 47.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ATP-synt_ab PF00006.20 EAU90318.2 - 5e-70 235.3 0.0 6.9e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EAU90318.2 - 7.2e-23 81.2 0.2 1.7e-22 79.9 0.1 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EAU90318.2 - 7.6e-18 64.4 1.5 2e-17 63.1 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Aldedh PF00171.17 EAU90319.1 - 7e-17 60.9 6.7 7.8e-14 50.8 2.3 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family ANTH PF07651.11 EAU90322.2 - 8e-51 172.3 0.2 1.2e-50 171.8 0.1 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EAU90322.2 - 0.023 14.5 0.1 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 ENTH domain DUF3652 PF12372.3 EAU90322.2 - 0.24 11.0 0.6 0.56 9.8 0.1 1.9 2 0 0 2 2 2 0 Huntingtin protein region Glyco_hydro_47 PF01532.15 EAU90323.2 - 7.5e-127 423.7 0.0 9e-127 423.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FGGY_C PF02782.11 EAU90324.2 - 1.2e-60 204.5 2.4 2e-60 203.7 1.7 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EAU90324.2 - 1.5e-58 198.0 0.2 2.9e-57 193.8 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CHAT PF12770.2 EAU90325.1 - 3.1e-32 111.8 0.0 5.5e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EAU90325.1 - 0.00042 19.9 2.5 6.4 6.4 0.0 5.2 3 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.1 EAU90325.1 - 0.031 14.9 6.1 36 5.3 0.0 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU90325.1 - 0.5 10.3 12.4 1 9.3 0.1 6.3 4 2 5 9 9 9 0 Tetratricopeptide repeat CHAT PF12770.2 EAU90326.2 - 2.8e-29 102.1 0.0 7.1e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU90326.2 - 1.5e-27 95.3 7.8 0.0063 16.4 0.0 12.4 8 2 6 14 14 14 8 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90326.2 - 9e-18 63.6 0.4 0.72 9.5 0.0 10.9 6 3 4 11 11 11 4 TPR repeat TPR_10 PF13374.1 EAU90326.2 - 1.5e-10 40.6 6.1 1.5 8.8 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90326.2 - 0.00021 20.7 6.3 13 5.6 0.0 8.0 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90326.2 - 0.0013 18.4 7.0 17 5.6 0.0 9.6 12 0 0 12 12 12 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAU90326.2 - 0.0049 16.5 0.0 14 5.7 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Flu_NS2 PF00601.14 EAU90326.2 - 0.13 12.4 0.0 8.8 6.6 0.0 3.5 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) DUF3310 PF11753.3 EAU90326.2 - 0.22 11.4 0.3 25 4.9 0.0 3.4 4 0 0 4 4 4 0 Protein of unknwon function (DUF3310) DUF1640 PF07798.6 EAU90327.1 - 5.4e-63 212.2 9.4 6.1e-63 212.0 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3153 PF11353.3 EAU90327.1 - 0.023 14.1 0.1 0.027 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DUF2077 PF09850.4 EAU90327.1 - 0.18 11.2 2.3 3.4 7.0 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DivIC PF04977.10 EAU90327.1 - 0.39 10.2 9.5 0.14 11.6 3.5 2.3 1 1 2 3 3 3 0 Septum formation initiator COG5 PF10392.4 EAU90327.1 - 1.2 9.0 6.3 2 8.4 0.7 2.8 1 1 2 3 3 3 0 Golgi transport complex subunit 5 FlaC_arch PF05377.6 EAU90327.1 - 1.3 8.9 6.7 0.56 10.1 0.5 2.9 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF2781 PF10914.3 EAU90328.2 - 5.6e-11 42.4 1.6 1.1e-10 41.4 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) WD40 PF00400.27 EAU90329.1 - 1.8e-12 46.5 0.1 0.0015 18.3 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Polysacc_deac_1 PF01522.16 EAU90331.1 - 4e-28 97.5 0.0 7e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Sec1 PF00995.18 EAU90332.1 - 1.5e-138 462.9 0.0 1.8e-138 462.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family AAA PF00004.24 EAU90333.1 - 6.6e-43 146.0 0.0 1.3e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU90333.1 - 1.9e-07 31.2 0.0 2.1e-05 24.5 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EAU90333.1 - 2.7e-07 30.3 0.1 2.6e-06 27.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EAU90333.1 - 4.7e-06 26.6 0.0 1.8e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EAU90333.1 - 6.9e-06 26.2 0.0 0.0012 19.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EAU90333.1 - 1e-05 24.7 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAU90333.1 - 4.2e-05 23.2 0.7 0.00025 20.7 0.5 2.1 1 1 1 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EAU90333.1 - 0.00036 21.3 0.6 0.001 19.8 0.1 2.3 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 EAU90333.1 - 0.0013 17.6 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EAU90333.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EAU90333.1 - 0.0027 16.5 0.0 0.005 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EAU90333.1 - 0.0028 17.5 0.0 0.0067 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EAU90333.1 - 0.0029 16.8 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EAU90333.1 - 0.0043 17.3 4.6 4.8 7.4 3.4 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EAU90333.1 - 0.0045 17.1 0.0 0.0086 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EAU90333.1 - 0.0056 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EAU90333.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU90333.1 - 0.0066 16.7 0.2 0.028 14.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EAU90333.1 - 0.0068 15.5 0.4 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin PhoH PF02562.11 EAU90333.1 - 0.0093 15.2 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_24 PF13479.1 EAU90333.1 - 0.011 15.3 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EAU90333.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EAU90333.1 - 0.013 14.9 0.0 0.051 13.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 EAU90333.1 - 0.014 14.8 0.2 0.076 12.4 0.1 2.0 1 1 1 2 2 2 0 AAA domain ResIII PF04851.10 EAU90333.1 - 0.014 15.2 0.1 0.032 14.0 0.0 1.7 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit DUF4200 PF13863.1 EAU90333.1 - 0.015 15.2 2.7 0.032 14.1 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NB-ARC PF00931.17 EAU90333.1 - 0.025 13.4 0.3 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EAU90333.1 - 0.041 13.5 0.0 0.17 11.5 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.1 EAU90333.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EAU90333.1 - 0.053 12.6 0.6 0.15 11.1 0.0 2.0 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EAU90333.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EAU90333.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EAU90333.1 - 0.13 12.3 0.0 0.36 10.8 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EAU90333.1 - 0.22 11.0 1.3 0.48 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain zf-CCCH PF00642.19 EAU90334.2 - 4.6e-18 64.4 54.2 4.1e-05 23.1 1.3 8.2 8 0 0 8 8 8 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EAU90334.2 - 2.7e-12 46.1 0.2 0.00096 18.7 0.0 5.0 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU90334.2 - 3.5e-09 36.5 0.0 0.13 12.2 0.0 5.2 5 0 0 5 5 5 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU90334.2 - 7.4e-09 35.3 0.1 0.21 11.4 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EAU90334.2 - 8.7e-06 25.6 2.1 8.7e-06 25.6 1.4 3.5 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EAU90334.2 - 9.6e-06 25.3 2.2 9.6e-06 25.3 1.6 2.9 2 0 0 2 2 2 1 IBR domain zf-C3HC4 PF00097.20 EAU90334.2 - 0.00076 19.0 1.5 0.00076 19.0 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU90334.2 - 0.0012 18.5 2.9 0.0012 18.5 2.0 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.1 EAU90334.2 - 0.0015 18.4 8.9 0.007 16.3 0.4 7.4 7 0 0 7 7 7 3 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_2 PF13639.1 EAU90334.2 - 0.0042 16.8 2.4 0.0042 16.8 1.7 3.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EAU90334.2 - 0.0056 16.3 1.5 0.0056 16.3 1.0 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAU90334.2 - 0.022 14.4 2.2 0.069 12.8 1.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-B_box PF00643.19 EAU90334.2 - 3.3 7.6 12.7 1.3 8.9 1.6 2.8 2 0 0 2 2 2 0 B-box zinc finger Glyco_transf_90 PF05686.7 EAU90335.2 - 8.3e-18 64.2 1.7 2.7e-17 62.5 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 90 5_nucleotid_C PF02872.13 EAU90336.2 - 5.5e-21 75.1 0.0 9.8e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EAU90336.2 - 8.3e-08 31.8 0.2 2.1e-07 30.5 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EAU90336.2 - 0.0002 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Metallophos_2 PF12850.2 EAU90336.2 - 0.0097 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Gemin7 PF11095.3 EAU90336.2 - 0.086 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Peptidase_M20 PF01546.23 EAU90337.2 - 7.4e-13 48.4 0.4 1.6e-12 47.2 0.3 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAU90337.2 - 9.5e-11 41.4 0.1 3.1e-10 39.7 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans PF04082.13 EAU90340.1 - 6.8e-19 67.7 0.3 1.2e-18 66.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU90340.1 - 3.3e-06 26.8 10.8 5.8e-06 26.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Speriolin_C PF15059.1 EAU90340.1 - 0.0081 16.1 0.0 0.41 10.6 0.0 2.3 2 0 0 2 2 2 1 Speriolin C-terminus YIEGIA PF14045.1 EAU90340.1 - 0.076 11.6 0.1 0.18 10.4 0.1 1.6 2 0 0 2 2 2 0 YIEGIA protein PDCD2_C PF04194.8 EAU90341.2 - 8.7e-33 113.2 1.2 2.8e-32 111.5 0.8 1.9 1 1 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain DUF3243 PF11588.3 EAU90342.1 - 0.035 14.0 1.2 0.16 11.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) Lipase_GDSL PF00657.17 EAU90342.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF2935 PF11155.3 EAU90342.1 - 0.45 10.6 2.2 30 4.7 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Nitroreductase PF00881.19 EAU90343.1 - 2.9e-28 98.7 0.0 5e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Nitroreductase family DUF3420 PF11900.3 EAU90343.1 - 0.05 13.7 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) DUF1805 PF08827.6 EAU90343.1 - 0.11 12.2 0.5 5.4 6.8 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1805) Rho_N PF07498.7 EAU90344.2 - 0.021 14.5 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain XhlA PF10779.4 EAU90345.1 - 0.026 14.4 3.0 0.068 13.0 2.0 1.6 1 0 0 1 1 1 0 Haemolysin XhlA DUF16 PF01519.11 EAU90345.1 - 0.89 9.8 5.6 0.1 12.7 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 Amidase PF01425.16 EAU90346.2 - 8.6e-90 301.6 0.0 6.7e-88 295.4 0.0 2.1 1 1 0 1 1 1 1 Amidase Peptidase_M50B PF13398.1 EAU90348.2 - 3.5e-32 111.4 16.0 4.7e-32 110.9 11.1 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Mgr1 PF08602.5 EAU90348.2 - 0.09 11.7 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Wzy_C PF04932.10 EAU90348.2 - 2.8 7.6 12.3 0.11 12.2 3.3 2.1 2 1 0 2 2 2 0 O-Antigen ligase Fis1_TPR_C PF14853.1 EAU90349.2 - 8.4e-24 83.2 1.7 1.3e-23 82.5 1.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EAU90349.2 - 3.3e-16 58.2 0.1 6.8e-16 57.2 0.0 1.6 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EAU90349.2 - 0.00025 20.7 1.2 0.00065 19.4 0.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90349.2 - 0.012 15.1 1.9 0.03 13.9 1.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EAU90349.2 - 0.015 15.4 0.2 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EAU90349.2 - 0.046 14.0 1.4 0.051 13.9 0.2 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU90349.2 - 0.058 13.8 0.6 0.15 12.5 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 EAU90350.2 - 2.2e-31 107.3 4.7 3.2e-15 55.4 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU90350.2 - 9.9e-23 79.9 0.4 8.6e-08 32.0 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU90350.2 - 1.2e-16 60.2 0.1 0.0015 18.3 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 EAU90350.2 - 0.043 13.8 0.0 5.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Smg-4/UPF3 family Nup35_RRM_2 PF14605.1 EAU90350.2 - 0.099 12.4 0.2 16 5.3 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Amidase PF01425.16 EAU90351.1 - 3.1e-101 339.3 0.0 3.7e-101 339.1 0.0 1.1 1 0 0 1 1 1 1 Amidase Ank PF00023.25 EAU90351.1 - 0.087 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Histone PF00125.19 EAU90352.2 - 9.6e-05 22.4 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EAU90352.2 - 0.04 13.8 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) dsrm PF00035.20 EAU90353.1 - 1.6e-09 38.1 0.0 2.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EAU90353.1 - 6.8e-09 35.7 0.0 1.8e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EAU90353.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease III domain RhoGAP PF00620.22 EAU90354.2 - 1.6e-11 44.0 0.3 4.6e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EAU90354.2 - 1.6e-09 37.7 0.1 8.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EAU90354.2 - 8.7e-05 22.1 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Nop14 PF04147.7 EAU90354.2 - 0.065 11.1 11.3 0.11 10.3 7.8 1.3 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 EAU90354.2 - 0.59 10.4 18.8 2.4 8.5 13.0 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.8 EAU90354.2 - 2 7.9 12.1 0.18 11.4 4.2 2.2 2 0 0 2 2 2 0 YL1 nuclear protein Sporozoite_P67 PF05642.6 EAU90354.2 - 2.3 5.9 13.5 0.06 11.2 4.5 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen eIF-3c_N PF05470.7 EAU90354.2 - 4.1 5.3 6.4 2.4 6.1 3.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FAM176 PF14851.1 EAU90354.2 - 4.8 6.8 7.9 16 5.1 5.5 1.9 1 0 0 1 1 1 0 FAM176 family SAGA-Tad1 PF12767.2 EAU90356.1 - 2.3e-43 148.6 0.0 3.9e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 EAU90356.1 - 0.00044 19.5 0.1 0.00078 18.8 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family WD40 PF00400.27 EAU90357.2 - 0.0043 16.8 2.1 0.87 9.5 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Ank PF00023.25 EAU90358.1 - 7.7e-32 107.5 3.1 5.8e-07 29.0 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EAU90358.1 - 2.4e-27 94.3 2.6 1.6e-08 34.5 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU90358.1 - 9e-27 93.2 0.2 1.9e-13 50.5 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAU90358.1 - 3e-20 70.2 1.5 0.0014 18.6 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EAU90358.1 - 1.4e-19 70.0 1.7 1.6e-08 34.8 0.3 4.7 2 1 3 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.7 EAU90358.1 - 3.4e-05 23.5 0.0 6.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EAU90358.1 - 0.00013 20.9 0.1 0.00043 19.2 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 EAU90358.1 - 0.0023 18.0 0.1 0.0087 16.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU90358.1 - 0.0035 17.3 0.1 0.052 13.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF463 PF04317.7 EAU90358.1 - 0.036 12.6 0.5 2.2 6.7 0.0 2.3 2 0 0 2 2 2 0 YcjX-like family, DUF463 RNase_H PF00075.19 EAU90359.2 - 8.6e-07 29.3 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EAU90359.2 - 0.028 14.7 1.5 0.04 14.2 0.1 1.9 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase CDK2AP PF09806.4 EAU90360.1 - 0.0054 16.9 2.7 0.012 15.8 1.8 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein DUF2207 PF09972.4 EAU90361.1 - 0.054 12.0 0.0 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) F-box-like PF12937.2 EAU90362.2 - 0.029 14.0 7.5 0.12 12.1 5.2 2.1 1 1 0 1 1 1 0 F-box-like NdhL PF10716.4 EAU90364.2 - 0.033 13.9 0.8 0.033 13.9 0.5 3.1 4 0 0 4 4 4 0 NADH dehydrogenase transmembrane subunit Actin PF00022.14 EAU90365.1 - 5.4e-122 407.0 0.0 6.5e-122 406.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EAU90365.1 - 0.01 14.4 0.0 0.027 13.0 0.0 1.6 1 1 0 1 1 1 0 MreB/Mbl protein Phos_pyr_kin PF08543.7 EAU90366.1 - 1.7e-10 40.5 0.0 2.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EAU90366.1 - 3.6e-07 29.6 0.6 8.6e-06 25.0 0.0 2.6 2 1 1 3 3 3 1 pfkB family carbohydrate kinase START PF01852.14 EAU90367.2 - 5.9e-07 29.0 0.0 3.6e-05 23.1 0.0 3.0 2 1 1 3 3 3 2 START domain LisH PF08513.6 EAU90368.2 - 0.0032 17.1 0.1 0.0052 16.5 0.1 1.3 1 0 0 1 1 1 1 LisH BTB PF00651.26 EAU90369.1 - 4e-05 23.5 0.0 7.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3248 PF11609.3 EAU90369.1 - 0.083 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Ribosomal_S19 PF00203.16 EAU90369.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S19 HALZ PF02183.13 EAU90373.2 - 0.078 12.7 1.6 0.9 9.3 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 EAU90373.2 - 0.082 12.7 0.0 16 5.3 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Apc15p PF05841.6 EAU90373.2 - 0.48 11.1 4.2 11 6.8 0.2 2.5 2 0 0 2 2 2 0 Apc15p protein Cep57_CLD_2 PF14197.1 EAU90373.2 - 0.52 10.2 3.9 4.7 7.2 2.7 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Ribosomal_L5_C PF00673.16 EAU90374.2 - 9.4e-23 79.7 0.0 1.4e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EAU90374.2 - 5.5e-19 67.6 0.0 5.5e-19 67.6 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein L5 DUF869 PF05911.6 EAU90375.2 - 0.00063 18.1 11.5 0.00075 17.8 8.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) ATG16 PF08614.6 EAU90375.2 - 0.0031 17.3 23.4 0.0094 15.7 9.3 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) KIAA1430 PF13879.1 EAU90375.2 - 0.0043 17.4 1.8 0.0043 17.4 1.2 2.6 2 1 0 2 2 2 1 KIAA1430 homologue DUF972 PF06156.8 EAU90375.2 - 0.0092 16.3 16.1 0.08 13.3 3.7 2.7 1 1 0 2 2 2 2 Protein of unknown function (DUF972) CENP-K PF11802.3 EAU90375.2 - 0.013 14.7 9.9 0.017 14.3 6.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K DUF4200 PF13863.1 EAU90375.2 - 0.035 14.0 27.7 0.32 10.9 9.1 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) MiaE_2 PF13794.1 EAU90375.2 - 0.078 12.4 1.3 0.21 11.0 0.1 1.9 1 1 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like FlaC_arch PF05377.6 EAU90375.2 - 0.16 11.9 7.3 0.39 10.6 0.9 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GAS PF13851.1 EAU90375.2 - 0.23 10.6 26.3 0.3 10.2 5.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 EAU90375.2 - 0.29 10.1 11.2 0.63 9.0 6.8 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein BMFP PF04380.8 EAU90375.2 - 0.53 10.4 15.1 0.098 12.8 0.6 3.5 3 1 0 3 3 2 0 Membrane fusogenic activity DivIVA PF05103.8 EAU90375.2 - 0.54 10.3 22.0 9.1 6.3 0.7 3.0 1 1 1 2 2 2 0 DivIVA protein FUSC PF04632.7 EAU90375.2 - 1.2 7.4 4.6 1.7 6.9 3.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CheZ PF04344.8 EAU90375.2 - 1.5 8.4 10.5 1.2 8.7 2.2 2.2 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ AAA_13 PF13166.1 EAU90375.2 - 2.1 6.7 19.6 2.9 6.2 13.6 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EAU90375.2 - 2.9 6.8 25.0 2.2 7.2 6.4 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 CCDC155 PF14662.1 EAU90375.2 - 4.9 6.7 22.4 2.9e+02 0.8 15.5 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 TPR_MLP1_2 PF07926.7 EAU90375.2 - 6.3 6.5 28.1 1.1 9.0 6.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.6 EAU90375.2 - 6.3 6.8 21.7 0.24 11.3 1.8 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.3 EAU90375.2 - 6.4 6.6 32.6 1.9 8.3 6.1 4.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 EAU90375.2 - 6.8 5.2 21.2 16 4.0 2.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 EAU90375.2 - 7.1 6.4 25.9 10 5.9 4.2 2.3 1 1 1 2 2 2 0 Tropomyosin like DUF812 PF05667.6 EAU90375.2 - 9 4.6 24.4 5.9 5.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1319 PF07028.6 EAU90375.2 - 9.9 6.3 15.0 5 7.3 3.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF4131 PF13567.1 EAU90379.2 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF883 PF05957.8 EAU90379.2 - 0.97 9.8 0.0 0.97 9.8 0.0 3.4 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF883) Podoplanin PF05808.6 EAU90380.1 - 2.7e-07 30.2 0.4 2.7e-07 30.2 0.2 1.7 2 0 0 2 2 2 1 Podoplanin zf-LITAF-like PF10601.4 EAU90381.2 - 0.095 12.5 0.1 0.095 12.5 0.1 1.9 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain FAM110_C PF14160.1 EAU90381.2 - 8.4 7.3 6.5 1.1 10.1 0.1 2.4 2 0 0 2 2 2 0 Centrosome-associated C terminus USP7_ICP0_bdg PF12436.3 EAU90382.2 - 1.8e-26 92.9 0.2 2.5e-23 82.6 0.2 3.2 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 EAU90382.2 - 9.3e-11 41.3 0.0 8.7e-10 38.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU90382.2 - 0.0061 16.0 0.0 0.0097 15.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF446 PF04287.7 EAU90382.2 - 0.13 12.0 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 tRNA pseudouridine synthase C Med20 PF08612.6 EAU90384.2 - 1.5e-11 43.8 0.0 4.4e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Osteopontin PF00865.13 EAU90384.2 - 0.027 13.7 1.5 0.039 13.1 1.0 1.1 1 0 0 1 1 1 0 Osteopontin AAA_16 PF13191.1 EAU90385.2 - 3.6e-19 69.4 0.1 1.1e-18 67.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ORC4_C PF14629.1 EAU90385.2 - 7.1e-10 38.6 0.0 2.5e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.24 EAU90385.2 - 0.00042 20.5 0.0 0.01 16.0 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU90385.2 - 0.0013 18.8 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EAU90385.2 - 0.0068 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EAU90385.2 - 0.019 13.9 0.0 0.074 11.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 EAU90385.2 - 0.02 14.5 0.0 0.078 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EAU90385.2 - 0.12 12.0 0.0 4.3 6.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.1 EAU90385.2 - 0.13 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.21 EAU90386.1 - 4.9e-23 81.6 0.0 1.4e-22 80.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EAU90386.1 - 1.3e-07 31.6 0.0 1.1e-05 25.3 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EAU90386.1 - 0.0037 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EAU90386.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ran_BP1 PF00638.13 EAU90388.2 - 1.7e-14 53.9 0.0 2.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Orbi_VP6 PF01516.11 EAU90388.2 - 7.9 5.4 21.0 0.54 9.2 5.9 2.4 2 0 0 2 2 2 0 Orbivirus helicase VP6 HATPase_c PF02518.21 EAU90389.2 - 9.7e-23 80.0 0.0 1.8e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EAU90389.2 - 9.2e-18 64.2 0.3 1.2e-09 38.1 0.0 2.7 3 0 0 3 3 3 2 Response regulator receiver domain DUF605 PF04652.11 EAU90389.2 - 2.7 7.2 16.4 4 6.7 11.3 1.2 1 0 0 1 1 1 0 Vta1 like zf-HC5HC2H_2 PF13832.1 EAU90390.2 - 9.9e-20 70.5 29.8 2.5e-19 69.2 4.0 4.3 3 1 0 3 3 3 2 PHD-zinc-finger like domain PHD PF00628.24 EAU90390.2 - 2.1e-15 56.1 56.0 4.6e-09 35.8 6.2 5.8 5 0 0 5 5 5 4 PHD-finger zf-HC5HC2H PF13771.1 EAU90390.2 - 1.7e-14 53.7 5.7 1.7e-14 53.7 4.0 4.4 3 2 1 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 EAU90390.2 - 5.8e-09 35.7 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 EAU90390.2 - 1e-07 31.1 28.6 0.00027 20.1 1.8 6.0 5 0 0 5 5 5 4 PHD-finger GATA PF00320.22 EAU90390.2 - 7.8e-06 25.1 6.2 7.8e-06 25.1 4.3 3.6 3 0 0 3 3 3 1 GATA zinc finger C1_1 PF00130.17 EAU90390.2 - 0.0011 18.6 56.1 0.045 13.4 6.3 6.3 6 1 1 7 7 7 4 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.14 EAU90390.2 - 0.02 14.5 2.4 0.067 12.8 1.7 2.0 1 0 0 1 1 1 0 AT hook motif UCH PF00443.24 EAU90391.2 - 2.5e-75 253.0 0.0 4.1e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU90391.2 - 2.1e-26 93.0 0.0 3.1e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EAU90391.2 - 4.5e-06 26.9 0.0 9.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain ADIP PF11559.3 EAU90393.2 - 6.1e-25 87.8 11.0 6.1e-25 87.8 7.6 3.6 3 1 1 4 4 3 2 Afadin- and alpha -actinin-Binding AIP3 PF03915.8 EAU90393.2 - 0.003 16.5 22.2 0.0088 15.0 2.3 2.2 2 0 0 2 2 2 2 Actin interacting protein 3 APG6 PF04111.7 EAU90393.2 - 0.005 15.9 13.5 0.005 15.9 9.4 2.4 2 0 0 2 2 2 1 Autophagy protein Apg6 LPP PF04728.8 EAU90393.2 - 0.02 14.7 0.5 3.9 7.3 0.1 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF3584 PF12128.3 EAU90393.2 - 0.047 11.0 36.5 0.13 9.5 9.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4140 PF13600.1 EAU90393.2 - 0.21 12.0 33.2 0.75 10.2 1.5 4.2 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) Fez1 PF06818.10 EAU90393.2 - 0.31 11.0 35.7 3.5 7.6 6.3 3.0 2 1 0 2 2 2 0 Fez1 Atg14 PF10186.4 EAU90393.2 - 0.45 9.4 31.3 0.031 13.2 7.7 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMPIT PF07851.8 EAU90393.2 - 0.88 8.5 19.7 0.039 13.0 4.9 2.2 2 0 0 2 2 2 0 TMPIT-like protein Macoilin PF09726.4 EAU90393.2 - 1 7.5 38.4 0.25 9.5 3.2 3.1 3 0 0 3 3 3 0 Transmembrane protein TPR_MLP1_2 PF07926.7 EAU90393.2 - 1.3 8.7 48.8 0.37 10.5 14.0 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 EAU90393.2 - 1.7 6.9 26.4 0.28 9.5 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 EAU90393.2 - 2.4 8.3 20.6 0.55 10.3 3.1 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FliJ PF02050.11 EAU90393.2 - 4.4 7.3 39.3 0.17 11.9 1.7 3.5 3 0 0 3 3 3 0 Flagellar FliJ protein Syndecan PF01034.15 EAU90396.2 - 0.012 15.2 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Syndecan domain F-box-like_2 PF13013.1 EAU90397.2 - 3.5e-05 23.4 1.6 3.8e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like domain F-box-like PF12937.2 EAU90397.2 - 0.00022 20.8 5.6 0.00022 20.8 3.9 3.5 4 1 0 4 4 4 1 F-box-like Tropomyosin PF00261.15 EAU90399.2 - 0.00025 20.2 31.2 0.00036 19.6 15.1 2.2 1 1 1 2 2 2 1 Tropomyosin AAA_13 PF13166.1 EAU90399.2 - 0.00094 17.7 11.1 0.0014 17.2 7.7 1.2 1 0 0 1 1 1 1 AAA domain TPR_MLP1_2 PF07926.7 EAU90399.2 - 0.0023 17.6 23.0 0.19 11.4 15.7 2.4 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein FH2 PF02181.18 EAU90399.2 - 0.0052 15.7 5.6 0.0052 15.7 3.9 2.2 1 1 1 2 2 2 1 Formin Homology 2 Domain DUF1664 PF07889.7 EAU90399.2 - 0.006 16.3 4.9 0.006 16.3 3.4 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EAU90399.2 - 0.0063 14.4 11.1 0.0076 14.1 7.7 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EAU90399.2 - 0.0071 15.5 2.3 0.011 14.9 1.3 1.5 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EAU90399.2 - 0.0097 15.7 22.1 0.0097 15.7 15.3 2.7 1 1 1 2 2 2 1 Tropomyosin like PspA_IM30 PF04012.7 EAU90399.2 - 0.012 15.0 3.9 0.012 15.0 2.7 3.0 1 1 2 3 3 3 0 PspA/IM30 family WXG100 PF06013.7 EAU90399.2 - 0.031 14.2 9.8 0.44 10.5 1.5 3.8 1 1 1 3 3 2 0 Proteins of 100 residues with WXG Phlebovirus_NSM PF07246.6 EAU90399.2 - 0.1 11.7 13.4 0.15 11.2 9.3 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3496 PF12001.3 EAU90399.2 - 0.12 12.6 14.6 0.18 12.0 6.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) Allexi_40kDa PF05549.6 EAU90399.2 - 0.13 11.5 10.7 2.1 7.5 3.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Sec8_exocyst PF04048.9 EAU90399.2 - 0.14 11.7 5.0 0.25 10.9 2.3 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain GAS PF13851.1 EAU90399.2 - 0.14 11.3 24.7 0.33 10.0 17.1 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EAU90399.2 - 0.25 11.3 23.6 0.34 10.9 6.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.3 EAU90399.2 - 0.42 7.8 23.4 0.1 9.8 12.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 EAU90399.2 - 0.49 9.9 25.5 1.4 8.5 15.4 2.5 1 1 1 2 2 2 0 IncA protein Flagellin_N PF00669.15 EAU90399.2 - 0.57 9.9 7.7 0.11 12.2 1.0 2.7 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region HALZ PF02183.13 EAU90399.2 - 0.61 9.8 7.0 0.44 10.2 0.2 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ax_dynein_light PF10211.4 EAU90399.2 - 1.1 9.0 25.2 0.1 12.4 2.0 3.1 1 1 1 3 3 3 0 Axonemal dynein light chain CENP-F_leu_zip PF10473.4 EAU90399.2 - 1.1 9.1 27.7 1.2 9.0 13.9 2.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 EAU90399.2 - 1.4 9.6 16.5 0.56 10.9 5.8 3.0 1 1 2 3 3 3 0 Occludin homology domain PLC-beta_C PF08703.5 EAU90399.2 - 1.4 8.5 24.5 0.73 9.5 8.5 2.6 1 1 2 3 3 3 0 PLC-beta C terminal DUF2935 PF11155.3 EAU90399.2 - 1.5 8.8 7.8 8.3 6.5 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Cluap1 PF10234.4 EAU90399.2 - 1.6 7.9 22.8 0.11 11.7 10.0 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 Cep57_CLD PF14073.1 EAU90399.2 - 1.6 8.5 26.0 1.1 9.0 15.2 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 TMF_DNA_bd PF12329.3 EAU90399.2 - 1.6 8.5 26.0 0.18 11.6 3.5 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding Filament PF00038.16 EAU90399.2 - 1.8 7.9 27.2 21 4.4 2.4 2.1 1 1 0 1 1 1 0 Intermediate filament protein DUF3573 PF12097.3 EAU90399.2 - 2 6.9 4.2 1.9 7.0 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Erp_C PF06780.6 EAU90399.2 - 2.2 8.0 14.9 5.7 6.7 4.6 2.3 1 1 1 2 2 2 0 Erp protein C-terminus DUF4200 PF13863.1 EAU90399.2 - 2.4 8.0 31.3 1.1 9.1 15.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Mnd1 PF03962.10 EAU90399.2 - 2.5 7.7 26.4 5.4 6.6 13.6 2.8 1 1 1 2 2 2 0 Mnd1 family TMPIT PF07851.8 EAU90399.2 - 2.9 6.8 16.2 0.36 9.8 7.3 1.9 1 1 1 2 2 2 0 TMPIT-like protein DUF4404 PF14357.1 EAU90399.2 - 3.1 8.2 18.6 1.6 9.2 3.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF2450 PF10475.4 EAU90399.2 - 3.6 6.3 12.1 10 4.9 8.1 1.9 1 1 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) CENP-H PF05837.7 EAU90399.2 - 4.1 7.6 22.5 0.14 12.3 6.5 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) APG6 PF04111.7 EAU90399.2 - 4.5 6.2 24.5 2.9 6.8 7.7 2.1 1 1 0 2 2 2 0 Autophagy protein Apg6 DUF972 PF06156.8 EAU90399.2 - 5.4 7.4 21.3 5.3 7.4 1.6 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF1759 PF03564.10 EAU90399.2 - 5.8 6.7 8.1 5.6 6.7 3.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) COG2 PF06148.6 EAU90399.2 - 6.5 6.6 16.2 2.9 7.7 4.1 3.3 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 EAP30 PF04157.11 EAU90399.2 - 7.7 5.6 15.9 4.1 6.5 1.9 3.1 2 1 1 3 3 3 0 EAP30/Vps36 family Sipho_Gp157 PF05565.6 EAU90399.2 - 7.8 6.0 16.7 0.19 11.2 2.6 2.8 1 1 2 3 3 2 0 Siphovirus Gp157 YjcZ PF13990.1 EAU90399.2 - 7.8 5.5 14.6 2.7 7.0 6.3 2.0 1 1 1 2 2 2 0 YjcZ-like protein Atg14 PF10186.4 EAU90399.2 - 8 5.3 27.9 1.2 8.0 13.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF87 PF01935.12 EAU90399.2 - 8 6.1 8.8 21 4.8 6.1 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF87 Spc7 PF08317.6 EAU90399.2 - 8.1 4.9 20.5 62 2.0 14.2 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein Cortex-I_coil PF09304.5 EAU90399.2 - 8.3 6.5 25.8 22 5.1 6.6 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil Striatin PF08232.7 EAU90399.2 - 8.4 6.7 25.3 12 6.2 8.4 3.0 1 1 2 3 3 3 0 Striatin family Syntaxin PF00804.20 EAU90399.2 - 8.4 6.6 18.6 11 6.1 6.4 3.1 1 1 1 2 2 2 0 Syntaxin zf-C3HC4_2 PF13923.1 EAU90400.2 - 1.5e-09 37.6 7.5 2.5e-09 37.0 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU90400.2 - 3.3e-09 36.2 5.1 4.9e-09 35.7 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU90400.2 - 3.6e-09 36.3 6.5 5.8e-09 35.6 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU90400.2 - 7.4e-09 35.3 8.1 1.2e-08 34.6 5.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EAU90400.2 - 1.5e-08 34.1 6.2 2.4e-08 33.4 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90400.2 - 3.1e-07 29.9 6.7 5.1e-07 29.3 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAU90400.2 - 2.7e-05 23.7 3.8 8e-05 22.2 2.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF2594 PF10769.4 EAU90400.2 - 0.0028 17.7 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2594) Leu_zip PF15294.1 EAU90400.2 - 0.0098 15.0 13.5 0.014 14.5 9.4 1.1 1 0 0 1 1 1 1 Leucine zipper DUF1664 PF07889.7 EAU90400.2 - 0.031 14.0 1.0 0.067 12.9 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-rbx1 PF12678.2 EAU90400.2 - 0.074 13.1 3.2 0.32 11.1 2.2 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EAU90400.2 - 0.12 11.9 6.2 0.28 10.7 4.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Dor1 PF04124.7 EAU90400.2 - 0.45 8.9 11.4 3.3 6.0 7.8 2.1 1 1 0 1 1 1 0 Dor1-like family zf-Apc11 PF12861.2 EAU90400.2 - 0.5 10.2 3.3 1.5 8.7 2.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4192 PF13830.1 EAU90400.2 - 0.86 9.1 10.4 0.69 9.4 6.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) CENP-F_leu_zip PF10473.4 EAU90400.2 - 1.7 8.5 24.2 0.061 13.1 7.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-MIZ PF02891.15 EAU90400.2 - 2.5 7.6 5.6 5.3 6.6 3.9 1.6 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger ERM PF00769.14 EAU90400.2 - 2.7 7.4 23.1 23 4.4 16.2 2.3 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Syntaxin_2 PF14523.1 EAU90400.2 - 3.3 7.8 11.6 0.31 11.1 2.0 2.3 1 1 1 2 2 2 0 Syntaxin-like protein Atg14 PF10186.4 EAU90400.2 - 3.9 6.3 17.7 39 3.0 12.3 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3450 PF11932.3 EAU90400.2 - 5.4 6.2 18.5 76 2.4 12.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 EAU90400.2 - 6.8 4.9 9.2 0.77 8.1 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Speriolin_N PF15058.1 EAU90400.2 - 7 6.5 7.8 26 4.6 5.4 2.1 1 1 0 1 1 1 0 Speriolin N terminus zf-RING_2 PF13639.1 EAU90401.1 - 4.4e-10 39.2 5.6 8.7e-10 38.2 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU90401.1 - 6.9e-10 38.6 8.7 1.3e-09 37.7 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EAU90401.1 - 1.2e-09 37.6 4.0 2.7e-09 36.5 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU90401.1 - 7.2e-09 35.5 7.7 1.7e-08 34.3 5.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90401.1 - 2.3e-08 33.6 6.0 4.9e-08 32.5 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU90401.1 - 1.5e-07 30.9 6.8 3e-07 29.9 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 EAU90401.1 - 5.2e-06 26.1 9.2 6e-06 25.9 6.4 1.1 1 0 0 1 1 1 1 IncA protein zf-RING_UBOX PF13445.1 EAU90401.1 - 0.00034 20.2 4.2 0.00078 19.1 2.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger UPF0242 PF06785.6 EAU90401.1 - 0.00035 19.3 10.9 0.00041 19.1 7.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) zf-Apc11 PF12861.2 EAU90401.1 - 0.015 15.0 1.7 0.026 14.3 1.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.10 EAU90401.1 - 0.026 13.7 13.0 0.035 13.3 9.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-NADH-PPase PF09297.6 EAU90401.1 - 0.039 13.4 1.1 0.089 12.3 0.2 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Filament PF00038.16 EAU90401.1 - 0.051 13.0 22.7 0.027 13.9 13.4 1.7 1 1 1 2 2 2 0 Intermediate filament protein SnoaL PF07366.7 EAU90401.1 - 0.072 12.6 0.3 0.29 10.7 0.0 2.0 2 1 0 2 2 2 0 SnoaL-like polyketide cyclase zf-rbx1 PF12678.2 EAU90401.1 - 0.085 12.9 2.2 0.48 10.5 1.5 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EAU90401.1 - 0.087 12.4 7.4 0.36 10.4 5.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EAU90401.1 - 0.096 12.4 5.3 0.22 11.3 3.6 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Sec20 PF03908.8 EAU90401.1 - 0.33 10.6 1.9 0.52 10.0 1.0 1.6 1 1 0 1 1 1 0 Sec20 CHD5 PF04420.9 EAU90401.1 - 0.36 10.4 1.3 0.69 9.5 0.9 1.4 1 0 0 1 1 1 0 CHD5-like protein DUF4200 PF13863.1 EAU90401.1 - 0.44 10.4 28.0 0.18 11.7 12.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EAU90401.1 - 0.68 7.7 7.0 0.78 7.5 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family L_lactis_ph-MCP PF06673.6 EAU90401.1 - 1.1 7.9 4.4 1.6 7.3 3.0 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Atg14 PF10186.4 EAU90401.1 - 1.6 7.6 20.3 3.2 6.5 14.1 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CAF-1_p150 PF11600.3 EAU90401.1 - 1.8 7.8 19.2 2.8 7.2 13.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 EAU90401.1 - 2.5 7.0 26.0 0.06 12.3 12.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3450 PF11932.3 EAU90401.1 - 3.1 7.0 21.8 1.2 8.3 10.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) G-gamma PF00631.17 EAU90401.1 - 7 6.4 8.5 0.25 11.1 0.9 2.4 2 1 0 2 2 2 0 GGL domain TMF_DNA_bd PF12329.3 EAU90401.1 - 9.7 6.0 19.2 7.5 6.4 1.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-C3HC4_2 PF13923.1 EAU90402.2 - 9.9e-10 38.2 11.1 1.6e-09 37.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU90402.2 - 1.6e-08 34.0 7.0 2.6e-08 33.4 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU90402.2 - 2.2e-08 33.5 10.0 3.9e-08 32.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU90402.2 - 1.2e-07 31.4 13.1 2.2e-07 30.6 9.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EAU90402.2 - 1.4e-07 31.1 10.9 2.4e-07 30.4 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EAU90402.2 - 8.7e-07 28.5 4.0 1.8e-06 27.5 2.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EAU90402.2 - 5.7e-06 25.9 10.5 9.8e-06 25.2 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain TPR_MLP1_2 PF07926.7 EAU90402.2 - 3e-05 23.7 17.7 3e-05 23.7 12.2 2.4 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EAU90402.2 - 0.00013 21.8 20.1 0.015 15.1 7.5 2.4 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Syntaxin_2 PF14523.1 EAU90402.2 - 0.0019 18.2 1.7 0.0019 18.2 1.2 2.2 1 1 1 2 2 1 1 Syntaxin-like protein DUF972 PF06156.8 EAU90402.2 - 0.005 17.1 2.7 0.005 17.1 1.9 3.4 1 1 2 3 3 3 1 Protein of unknown function (DUF972) GAS PF13851.1 EAU90402.2 - 0.021 14.0 27.3 0.011 14.9 8.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EAU90402.2 - 0.034 12.8 20.7 0.014 14.0 10.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-RING_6 PF14835.1 EAU90402.2 - 0.036 13.8 5.7 0.076 12.8 4.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Scaffolding_pro PF11418.3 EAU90402.2 - 0.051 13.8 8.6 0.042 14.1 4.5 2.0 2 1 0 2 2 1 0 Phi29 scaffolding protein DUF2205 PF10224.4 EAU90402.2 - 0.056 13.0 18.6 0.12 11.9 5.0 3.4 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) AAA_13 PF13166.1 EAU90402.2 - 0.059 11.8 13.0 0.079 11.4 9.0 1.1 1 0 0 1 1 1 0 AAA domain PB1-F2 PF11986.3 EAU90402.2 - 0.066 13.2 0.3 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Influenza A Proapoptotic protein DUF4201 PF13870.1 EAU90402.2 - 0.17 11.3 26.0 0.087 12.2 15.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2353 PF09789.4 EAU90402.2 - 0.18 11.0 17.0 0.34 10.1 11.8 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) WEMBL PF05701.6 EAU90402.2 - 0.18 10.2 25.8 0.28 9.5 17.9 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Hormone_1 PF00103.15 EAU90402.2 - 0.19 11.0 4.7 4.1 6.6 0.8 2.2 2 0 0 2 2 2 0 Somatotropin hormone family Nup54 PF13874.1 EAU90402.2 - 0.22 11.2 14.6 0.1 12.2 7.6 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Rab5-bind PF09311.6 EAU90402.2 - 0.27 11.1 30.8 0.83 9.5 17.9 2.8 1 1 1 2 2 2 0 Rabaptin-like protein zf-rbx1 PF12678.2 EAU90402.2 - 0.44 10.6 5.4 1.3 9.2 3.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger APG6 PF04111.7 EAU90402.2 - 0.47 9.4 27.0 1.6 7.6 18.5 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 DOG1 PF14144.1 EAU90402.2 - 0.73 9.9 4.4 12 5.9 0.2 2.8 1 1 1 2 2 2 0 Seed dormancy control Prp19 PF08606.6 EAU90402.2 - 0.75 9.5 7.4 3.1 7.5 0.9 2.9 1 1 1 2 2 2 0 Prp19/Pso4-like zf-RING_4 PF14570.1 EAU90402.2 - 1.1 8.9 9.4 2.3 7.8 6.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Hemerythrin PF01814.18 EAU90402.2 - 1.3 9.1 17.6 0.23 11.6 8.6 2.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain CENP-F_leu_zip PF10473.4 EAU90402.2 - 1.4 8.7 29.4 9.1 6.1 10.5 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 EAU90402.2 - 1.6 8.6 5.2 14 5.6 1.2 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Macoilin PF09726.4 EAU90402.2 - 1.7 6.8 21.5 3.3 5.8 14.9 1.4 1 0 0 1 1 1 0 Transmembrane protein FYVE PF01363.16 EAU90402.2 - 2.3 8.1 6.0 10 6.0 4.2 2.0 1 1 0 1 1 1 0 FYVE zinc finger Laminin_II PF06009.7 EAU90402.2 - 2.5 7.8 12.2 2 8.1 3.5 2.3 1 1 1 2 2 2 0 Laminin Domain II IBR PF01485.16 EAU90402.2 - 2.5 8.0 7.3 13 5.7 4.9 2.3 1 1 0 1 1 1 0 IBR domain HALZ PF02183.13 EAU90402.2 - 3 7.6 30.8 1.3 8.7 0.3 4.8 4 1 1 5 5 5 0 Homeobox associated leucine zipper IncA PF04156.9 EAU90402.2 - 3.4 7.2 35.0 0.24 10.9 3.4 2.4 2 1 1 3 3 2 0 IncA protein NYD-SP28_assoc PF14775.1 EAU90402.2 - 4 7.2 13.7 0.98 9.1 0.4 3.8 2 1 2 4 4 4 0 Sperm tail C-terminal domain UPF0242 PF06785.6 EAU90402.2 - 4.4 5.8 17.3 14 4.2 12.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) bZIP_Maf PF03131.12 EAU90402.2 - 4.5 7.6 25.2 0.65 10.3 5.2 3.5 2 1 0 3 3 3 0 bZIP Maf transcription factor Rootletin PF15035.1 EAU90402.2 - 4.8 7.1 27.4 0.36 10.7 14.6 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FliD_C PF07195.7 EAU90402.2 - 5.2 6.2 8.8 7.8 5.7 3.1 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TMCO5 PF14992.1 EAU90402.2 - 5.6 6.0 24.4 0.48 9.5 0.7 2.2 1 1 1 2 2 2 0 TMCO5 family DUF2408 PF10303.4 EAU90402.2 - 7.3 6.7 11.4 0.11 12.6 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF3450 PF11932.3 EAU90402.2 - 7.6 5.7 19.1 0.58 9.3 4.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ERM PF00769.14 EAU90402.2 - 7.8 5.9 36.2 1.2 8.5 12.4 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HOOK PF05622.7 EAU90402.2 - 8.5 4.0 25.5 0.6 7.8 4.5 2.0 1 1 1 2 2 2 0 HOOK protein Mod_r PF07200.8 EAU90402.2 - 8.8 6.2 24.5 3.6 7.5 7.9 2.6 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein BTV_NS2 PF04514.7 EAU90402.2 - 9.2 5.0 14.7 18 4.1 10.2 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Syntaxin-6_N PF09177.6 EAU90402.2 - 9.6 6.6 12.8 3 8.3 2.7 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal NAD_binding_10 PF13460.1 EAU90403.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAU90403.1 - 2.9e-05 23.6 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EAU90403.1 - 0.001 19.3 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EAU90403.1 - 0.051 12.4 0.1 5.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein NMO PF03060.10 EAU90404.1 - 6.9e-63 212.7 0.1 8.3e-63 212.5 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EAU90404.1 - 9.8e-05 21.3 0.2 0.00078 18.4 0.2 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EAU90404.1 - 0.0012 17.8 1.6 0.0018 17.2 1.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Hormone_1 PF00103.15 EAU90405.2 - 4.6 6.5 12.8 6.8 5.9 4.8 2.5 1 1 1 2 2 2 0 Somatotropin hormone family p450 PF00067.17 EAU90406.2 - 6.7e-53 179.8 0.0 9.1e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RhoGEF PF00621.15 EAU90407.2 - 1.1e-69 233.9 4.0 9.2e-38 129.9 1.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 EAU90407.2 - 8.9e-58 195.8 0.0 1.4e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EAU90407.2 - 5.5e-12 45.7 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EAU90407.2 - 0.00089 19.4 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 PH domain DEP PF00610.16 EAU90407.2 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Methyltransf_12 PF08242.7 EAU90408.1 - 2.3e-12 47.2 0.0 7.4e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU90408.1 - 6.3e-11 42.8 0.0 1.5e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU90408.1 - 3e-10 40.3 0.0 5.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU90408.1 - 8.7e-10 38.5 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU90408.1 - 1.3e-08 35.2 0.0 4.7e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU90408.1 - 1.6e-08 34.2 0.0 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EAU90408.1 - 9.9e-05 23.1 0.0 0.001 19.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU90408.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EAU90408.1 - 0.0012 18.4 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 2 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.12 EAU90408.1 - 0.0038 16.2 0.0 0.0095 14.9 0.0 1.5 1 1 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.9 EAU90408.1 - 0.0046 16.3 0.0 0.0087 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EAU90408.1 - 0.082 11.9 0.0 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase CheR PF01739.13 EAU90408.1 - 0.093 12.0 0.0 6.6 5.9 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain F-box-like PF12937.2 EAU90409.1 - 0.023 14.4 1.3 0.048 13.3 0.3 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EAU90409.1 - 0.065 12.9 6.0 0.23 11.1 1.0 3.6 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 EAU90410.2 - 1.2e-06 28.1 6.1 1.2e-05 24.9 4.2 2.5 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EAU90410.2 - 0.61 9.8 6.9 28 4.4 0.2 4.1 4 0 0 4 4 4 0 F-box domain Amidase PF01425.16 EAU90414.1 - 3.1e-117 392.1 0.2 3.7e-117 391.8 0.1 1.1 1 0 0 1 1 1 1 Amidase WD40 PF00400.27 EAU90415.2 - 2.8e-24 84.0 2.5 7.2e-08 32.0 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4123 PF13503.1 EAU90415.2 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Nup160 PF11715.3 EAU90415.2 - 0.043 11.9 0.0 0.09 10.9 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 RNA_pol_Rpc4 PF05132.9 EAU90415.2 - 0.3 11.0 4.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF1604 PF07713.8 EAU90416.1 - 7e-39 131.5 0.5 7e-39 131.5 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EAU90416.1 - 6.1e-08 32.3 0.3 9.3e-07 28.5 0.1 2.7 2 0 0 2 2 2 1 G-patch domain DUF1024 PF06260.7 EAU90416.1 - 0.022 14.9 0.1 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) G-patch_2 PF12656.2 EAU90416.1 - 0.043 13.6 0.0 0.043 13.6 0.0 4.9 7 0 0 7 7 7 0 DExH-box splicing factor binding site Sec62 PF03839.11 EAU90416.1 - 2.2 7.6 9.7 2 7.7 5.0 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 DivIC PF04977.10 EAU90417.1 - 0.12 11.8 0.7 0.31 10.5 0.5 1.7 1 0 0 1 1 1 0 Septum formation initiator AAA_13 PF13166.1 EAU90417.1 - 0.37 9.2 1.1 0.64 8.4 0.8 1.3 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.1 EAU90417.1 - 1.2 9.1 8.2 0.73 9.8 1.7 2.8 1 1 1 2 2 2 0 Up-regulated During Septation IncA PF04156.9 EAU90417.1 - 4.3 6.8 9.4 0.14 11.7 1.7 2.2 2 1 0 2 2 2 0 IncA protein MFS_1 PF07690.11 EAU90418.2 - 3.8e-22 78.4 22.9 3.8e-22 78.4 15.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PACT_coil_coil PF10495.4 EAU90419.2 - 1.3e-13 50.6 0.1 1.3e-12 47.4 0.0 2.8 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein SlyX PF04102.7 EAU90419.2 - 6.3e-05 23.2 5.8 6.3e-05 23.2 4.1 14.5 7 4 5 13 13 13 1 SlyX DUF904 PF06005.7 EAU90419.2 - 0.00056 20.1 5.2 0.00056 20.1 3.6 15.8 7 3 5 12 12 12 2 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 EAU90419.2 - 0.002 17.3 44.2 0.082 12.0 2.6 6.2 3 2 3 6 6 6 5 Reovirus sigma C capsid protein IncA PF04156.9 EAU90419.2 - 0.0031 17.1 13.8 0.0031 17.1 9.6 10.2 2 2 5 9 9 9 2 IncA protein TPR_MLP1_2 PF07926.7 EAU90419.2 - 0.0031 17.2 20.6 0.0031 17.2 14.2 11.6 3 2 9 12 12 12 3 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 EAU90419.2 - 0.0058 16.7 3.0 0.0058 16.7 2.1 9.3 3 2 6 9 9 9 5 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 EAU90419.2 - 0.2 10.0 119.1 0.041 12.3 25.5 6.2 2 2 4 6 6 6 0 AAA domain zf-C2H2_4 PF13894.1 EAU90420.1 - 0.016 15.4 1.1 0.034 14.4 0.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger PBP1_TM PF14812.1 EAU90420.1 - 0.38 11.0 7.0 0.69 10.2 4.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EAU90420.1 - 1.1 8.8 5.7 1.7 8.1 4.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EAU90420.1 - 1.2 8.9 3.5 2.2 8.0 2.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 EAU90420.1 - 2.9 7.0 4.8 4.3 6.5 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein KH_1 PF00013.24 EAU90423.2 - 9.5e-05 21.9 0.1 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EAU90423.2 - 0.0027 17.3 1.5 0.011 15.3 0.1 2.4 2 0 0 2 2 2 1 KH domain SUR7 PF06687.7 EAU90424.2 - 3.6e-06 26.7 7.2 9.9e-06 25.2 5.0 1.6 1 1 0 1 1 1 1 SUR7/PalI family DUF1752 PF08550.5 EAU90425.2 - 1e-07 31.4 8.5 1.9e-07 30.4 5.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RhoGEF PF00621.15 EAU90429.2 - 6.9e-70 234.5 9.6 9e-36 123.4 0.1 2.6 3 0 0 3 3 3 2 RhoGEF domain CNH PF00780.17 EAU90429.2 - 1e-64 218.6 0.0 1.6e-64 218.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EAU90429.2 - 2.2e-17 63.2 0.0 6.7e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EAU90429.2 - 1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 PH domain DEP PF00610.16 EAU90429.2 - 0.0027 17.4 1.6 0.0044 16.7 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) UBX PF00789.15 EAU90430.1 - 4.6e-12 45.8 0.3 1.4e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 EAU90430.1 - 0.0016 18.1 0.0 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 EAU90430.1 - 0.11 12.6 3.3 0.12 12.4 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) APG6 PF04111.7 EAU90430.1 - 2.5 7.0 22.4 3.3 6.6 15.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 F-box-like PF12937.2 EAU90432.2 - 8.7e-06 25.3 1.7 1.7e-05 24.4 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU90432.2 - 0.00073 19.1 1.2 0.0016 18.0 0.8 1.6 1 0 0 1 1 1 1 F-box domain CDO_I PF05995.7 EAU90432.2 - 0.058 12.5 0.1 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I BIR PF00653.16 EAU90433.2 - 2e-32 111.4 4.8 6e-16 58.6 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-BED PF02892.10 EAU90433.2 - 0.022 14.4 0.1 8.4 6.2 0.0 3.0 3 0 0 3 3 3 0 BED zinc finger WAPL PF07814.8 EAU90434.2 - 8e-06 24.8 0.0 5e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Peptidase_C15 PF01470.12 EAU90435.2 - 0.00018 21.4 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 Pyroglutamyl peptidase BCS1_N PF08740.6 EAU90436.2 - 1.2e-28 100.0 0.4 1.9e-28 99.3 0.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EAU90436.2 - 3.2e-19 69.4 0.0 7.8e-19 68.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EAU90436.2 - 6.1e-05 23.8 0.1 0.00023 21.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EAU90436.2 - 0.00065 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EAU90436.2 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EAU90436.2 - 0.0059 15.6 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EAU90436.2 - 0.0084 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EAU90436.2 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EAU90436.2 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU90436.2 - 0.02 15.2 0.1 0.091 13.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.8 EAU90436.2 - 0.027 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EAU90436.2 - 0.04 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 EAU90436.2 - 0.044 12.4 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_22 PF13401.1 EAU90436.2 - 0.046 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAU90436.2 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EAU90436.2 - 0.053 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EAU90436.2 - 0.062 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EAU90436.2 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Pantoate_ligase PF02569.10 EAU90437.2 - 5e-88 294.4 0.0 6.1e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase BAF1_ABF1 PF04684.8 EAU90437.2 - 0.15 10.8 0.0 0.45 9.3 0.0 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor MscS_porin PF12795.2 EAU90441.1 - 0.0018 17.6 3.0 0.0028 17.0 2.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DUF605 PF04652.11 EAU90441.1 - 2.6 7.3 10.7 3 7.1 7.4 1.1 1 0 0 1 1 1 0 Vta1 like Ribonuc_P_40 PF08584.6 EAU90442.2 - 6.7e-26 90.9 0.0 1.6e-16 60.1 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease P 40kDa (Rpp40) subunit HMG_CoA_synt_C PF08540.5 EAU90443.1 - 1.8e-89 299.9 0.1 2.2e-89 299.7 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EAU90443.1 - 1.7e-84 281.7 0.1 2.3e-84 281.2 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 EAU90443.1 - 0.002 17.7 0.2 0.022 14.4 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3455 PF11937.3 EAU90444.1 - 9e-18 64.8 0.0 1.2e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Methyltransf_23 PF13489.1 EAU90445.1 - 1.8e-25 89.5 0.0 2.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU90445.1 - 4.2e-16 59.2 0.0 9.3e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU90445.1 - 1.2e-14 54.5 0.0 3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU90445.1 - 3.7e-14 53.2 0.0 7.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU90445.1 - 3.6e-13 49.3 0.0 7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAU90445.1 - 2.3e-07 30.2 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EAU90445.1 - 2.1e-06 28.0 0.0 1.2e-05 25.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU90445.1 - 2.2e-06 27.7 0.1 7.3e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAU90445.1 - 5.7e-05 22.3 0.0 9.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EAU90445.1 - 0.00089 18.6 0.3 0.0023 17.3 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EAU90445.1 - 0.022 13.4 0.0 0.13 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.7 EAU90445.1 - 0.022 14.1 0.3 0.052 12.9 0.1 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW TehB PF03848.9 EAU90445.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.6 EAU90445.1 - 0.063 12.7 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 EAU90445.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain E1-E2_ATPase PF00122.15 EAU90446.1 - 3.5e-53 179.9 1.8 3.5e-53 179.9 1.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EAU90446.1 - 2.3e-34 119.7 2.7 3.6e-34 119.0 0.9 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EAU90446.1 - 2.3e-24 85.2 0.0 5e-11 42.5 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 EAU90446.1 - 1.2e-09 38.6 0.0 1.3e-08 35.2 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EAU90446.1 - 0.00013 21.6 1.6 0.0011 18.6 0.4 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 EAU90446.1 - 0.14 11.7 2.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) DUF3879 PF12995.2 EAU90447.2 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) DUF4600 PF15372.1 EAU90447.2 - 0.23 11.7 2.2 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) IncA PF04156.9 EAU90447.2 - 0.36 10.4 3.7 0.76 9.3 2.6 1.5 1 0 0 1 1 1 0 IncA protein Rnk_N PF14760.1 EAU90447.2 - 1 9.4 5.2 7.6 6.6 0.6 3.3 2 1 1 3 3 3 0 Rnk N-terminus PH_10 PF15411.1 EAU90449.2 - 2.3e-28 98.7 0.0 4.3e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 EAU90449.2 - 1e-05 25.2 2.4 2e-05 24.3 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 EAU90449.2 - 0.0011 18.6 2.3 0.0027 17.4 0.0 2.9 3 1 0 3 3 3 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 EAU90449.2 - 0.0026 17.3 1.5 0.0044 16.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90449.2 - 0.0031 17.2 0.7 0.007 16.0 0.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EAU90449.2 - 0.01 15.8 1.0 0.097 12.7 0.9 2.1 1 1 1 2 2 2 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 EAU90449.2 - 0.093 12.4 1.0 0.19 11.4 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU90449.2 - 0.17 11.9 0.7 0.41 10.7 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PMT PF02366.13 EAU90450.1 - 4.4e-76 255.4 21.5 4.4e-76 255.4 14.9 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EAU90450.1 - 1e-14 54.4 2.1 1e-14 54.4 1.4 2.5 2 1 1 3 3 3 2 MIR domain PX PF00787.19 EAU90451.2 - 1.2e-15 57.3 0.1 2.5e-15 56.2 0.1 1.5 1 0 0 1 1 1 1 PX domain DOPA_dioxygen PF08883.6 EAU90452.2 - 0.00011 22.1 0.2 0.00015 21.7 0.1 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PALP PF00291.20 EAU90453.2 - 7.7e-52 176.4 0.6 9e-52 176.1 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PI3_PI4_kinase PF00454.22 EAU90455.2 - 8.2e-47 159.6 0.0 1.6e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EAU90455.2 - 6e-18 65.0 2.8 7.8e-18 64.6 0.1 2.7 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EAU90455.2 - 3.4e-10 39.1 0.0 9.2e-10 37.7 0.0 1.8 1 0 0 1 1 1 1 FATC domain Pkinase PF00069.20 EAU90456.2 - 2.4e-72 243.1 0.0 3.4e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU90456.2 - 1.5e-47 161.8 0.0 2.4e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EAU90456.2 - 1.7e-22 79.5 0.1 4.4e-22 78.2 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EAU90456.2 - 0.00054 19.0 0.0 0.00089 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU90456.2 - 3.3 7.3 6.0 0.74 9.5 0.1 2.6 3 1 1 4 4 4 0 Phosphotransferase enzyme family BCS1_N PF08740.6 EAU90458.2 - 4e-26 91.7 4.7 4e-26 91.7 3.3 2.4 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 EAU90458.2 - 4.9e-17 62.3 0.0 5.1e-16 59.0 0.0 2.7 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Caldesmon PF02029.10 EAU90458.2 - 7.6e-10 37.8 22.8 8.7e-10 37.6 15.8 1.2 1 0 0 1 1 1 1 Caldesmon DUF815 PF05673.8 EAU90458.2 - 0.00029 19.8 0.0 0.00074 18.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EAU90458.2 - 0.00087 19.3 0.1 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EAU90458.2 - 0.0074 16.0 0.0 0.023 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAU90458.2 - 0.04 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAU90458.2 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAU90458.2 - 0.076 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EAU90458.2 - 0.095 13.0 0.0 0.095 13.0 0.0 4.0 3 1 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EAU90458.2 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Zip PF02535.17 EAU90458.2 - 1.1 8.1 7.7 1.8 7.4 5.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_17 PF13207.1 EAU90458.2 - 1.5 9.6 16.2 16 6.3 9.5 3.3 2 1 0 2 2 2 0 AAA domain MIP-T3 PF10243.4 EAU90458.2 - 2 6.7 56.5 0.24 9.8 34.7 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DHHW PF14286.1 EAU90458.2 - 2.2 7.5 12.7 4.9 6.3 8.8 1.6 1 0 0 1 1 1 0 DHHW protein ResIII PF04851.10 EAU90458.2 - 2.2 8.0 0.0 2.2 8.0 0.0 2.8 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit Hid1 PF12722.2 EAU90458.2 - 5 4.6 13.9 6.7 4.2 9.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein An_peroxidase PF03098.10 EAU90460.2 - 5e-80 269.3 0.0 9e-78 261.9 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase PKD_channel PF08016.7 EAU90461.2 - 2.1e-05 23.1 15.9 0.00063 18.2 1.0 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ank_2 PF12796.2 EAU90462.2 - 7.3e-12 45.4 0.2 4e-08 33.4 0.2 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90462.2 - 1.8e-10 40.1 3.5 2.6e-05 23.8 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EAU90462.2 - 3.5e-09 36.0 0.3 0.0011 18.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EAU90462.2 - 1.9e-08 34.5 0.3 5.2e-06 26.8 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90462.2 - 1.5e-07 31.4 0.6 0.0074 16.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EAU90462.2 - 7.2e-05 22.3 0.2 0.0013 18.3 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain DUF3562 PF12085.3 EAU90462.2 - 0.035 13.9 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) SF-assemblin PF06705.6 EAU90462.2 - 0.082 12.0 3.0 0.14 11.2 2.1 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Filament PF00038.16 EAU90462.2 - 0.084 12.3 2.2 0.14 11.5 1.5 1.3 1 0 0 1 1 1 0 Intermediate filament protein FEZ PF07763.8 EAU90462.2 - 0.096 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 FEZ-like protein Phage_GP20 PF06810.6 EAU90462.2 - 0.12 11.7 1.0 0.22 10.9 0.7 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IMD PF08397.6 EAU90462.2 - 0.16 11.2 1.6 0.27 10.5 1.1 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain WD40 PF00400.27 EAU90463.1 - 3.3e-53 175.7 8.8 4.7e-10 38.9 0.2 8.2 7 2 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EAU90463.1 - 9e-13 47.2 1.1 1.6e-12 46.4 0.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EAU90463.1 - 0.00033 19.8 0.1 4.6 6.2 0.0 3.7 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EAU90463.1 - 0.1 11.3 0.0 6.8 5.3 0.0 2.4 1 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 EAU90463.1 - 1 7.4 4.6 7.5 4.5 1.8 3.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 zf-CCCH PF00642.19 EAU90465.2 - 4.2e-09 35.8 18.9 0.0004 19.9 0.8 4.5 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SURF2 PF05477.6 EAU90465.2 - 1 8.4 7.3 1.7 7.7 5.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) GRP PF07172.6 EAU90465.2 - 8.3 6.9 21.9 0.16 12.4 7.7 2.3 2 0 0 2 2 2 0 Glycine rich protein family DnaJ-X PF14308.1 EAU90466.1 - 4.1e-55 186.2 0.0 4.1e-55 186.2 0.0 2.4 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EAU90466.1 - 2.5e-27 94.3 2.7 7.5e-27 92.8 1.9 1.9 1 0 0 1 1 1 1 DnaJ domain Peptidase_M20 PF01546.23 EAU90467.2 - 4.2e-07 29.6 0.2 5.9e-07 29.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EAU90467.2 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase dimerisation domain Pkinase PF00069.20 EAU90468.2 - 1.7e-64 217.5 0.0 2.3e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU90468.2 - 2.1e-49 167.9 0.0 2.9e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EAU90468.2 - 2e-07 30.6 2.8 3.6e-07 29.7 1.9 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kinase-like PF14531.1 EAU90468.2 - 0.014 14.3 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 EAU90468.2 - 0.11 11.8 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 EAU90468.2 - 0.15 11.3 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 EAU90468.2 - 0.16 10.7 0.1 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Prok-RING_1 PF14446.1 EAU90468.2 - 0.24 11.1 3.0 0.53 10.0 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EAU90468.2 - 0.63 9.7 4.1 1.3 8.7 2.8 1.5 1 0 0 1 1 1 0 PHD-finger Tnp_zf-ribbon_2 PF13842.1 EAU90468.2 - 3 8.3 6.0 7.4 7.0 4.2 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon TFIIS_M PF07500.9 EAU90469.1 - 6.2e-17 61.7 1.8 1.4e-16 60.6 1.2 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EAU90469.1 - 6e-08 32.2 9.8 1e-07 31.5 6.8 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 EAU90469.1 - 1.8e-06 28.4 0.0 3.5e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD_2 PF13831.1 EAU90469.1 - 0.92 8.8 5.7 1.5 8.1 3.9 1.4 1 0 0 1 1 1 0 PHD-finger ADH_N PF08240.7 EAU90470.2 - 6.7e-20 70.8 1.0 1.2e-19 70.0 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EAU90470.2 - 2.2e-16 59.5 0.0 3.2e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU90470.2 - 0.033 15.0 0.0 0.064 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EAU90470.2 - 0.065 13.2 0.1 0.17 11.9 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 EAU90471.2 - 3.1e-56 190.4 0.0 6.1e-55 186.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU90471.2 - 3.9e-23 81.8 0.1 2.8e-18 65.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAU90471.2 - 0.00035 19.6 0.9 0.00093 18.2 0.1 2.1 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EAU90471.2 - 0.0038 17.7 0.7 0.0076 16.7 0.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 EAU90471.2 - 0.0079 15.2 0.1 0.022 13.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EAU90471.2 - 0.009 14.8 0.1 0.019 13.8 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.18 EAU90471.2 - 0.02 14.6 0.6 0.33 10.6 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EAU90471.2 - 0.072 12.4 1.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family DUF1712 PF08217.6 EAU90472.2 - 9e-19 67.1 0.0 1.4e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF4637 PF15470.1 EAU90472.2 - 3.6 7.1 7.7 8.9 5.8 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) UCH PF00443.24 EAU90473.2 - 5.5e-77 258.5 0.0 1e-76 257.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU90473.2 - 8.7e-21 74.6 0.0 8.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EAU90473.2 - 2.1e-15 56.8 0.0 5.5e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 EAU90473.2 - 0.0029 17.0 0.0 0.0061 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Dak1 PF02733.12 EAU90474.2 - 2.9e-115 384.3 0.9 4e-115 383.8 0.7 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EAU90474.2 - 1.3e-44 151.9 0.3 2.2e-44 151.2 0.2 1.3 1 0 0 1 1 1 1 DAK2 domain DUF4261 PF14080.1 EAU90474.2 - 0.056 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) Sugar_tr PF00083.19 EAU90475.1 - 1.3e-135 452.4 20.6 1.5e-135 452.2 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EAU90475.1 - 7.7e-22 77.4 26.4 7.7e-22 77.4 18.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Cyto_heme_lyase PF01265.12 EAU90476.1 - 6.1e-73 245.5 0.1 6.9e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Tim44 PF04280.10 EAU90477.1 - 7.7e-34 116.7 0.6 7.7e-34 116.7 0.4 1.9 2 0 0 2 2 2 1 Tim44-like domain DMPK_coil PF08826.5 EAU90477.1 - 0.023 14.5 0.2 0.023 14.5 0.1 2.7 3 0 0 3 3 3 0 DMPK coiled coil domain like Complex1_LYR_1 PF13232.1 EAU90477.1 - 0.16 12.1 2.5 1.8 8.7 1.7 2.8 1 1 0 1 1 1 0 Complex1_LYR-like PIF1 PF05970.9 EAU90478.2 - 7.2e-57 192.9 0.5 7.1e-45 153.5 0.2 2.2 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAU90478.2 - 2.3e-16 59.9 0.0 4.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EAU90478.2 - 7.9e-07 27.2 0.9 1.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 EAU90478.2 - 1e-05 25.7 0.0 2.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU90478.2 - 9.2e-05 22.1 0.2 0.00023 20.8 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EAU90478.2 - 0.00011 21.8 0.3 1.2 8.6 0.0 3.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EAU90478.2 - 0.00016 21.7 0.7 0.00069 19.7 0.0 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EAU90478.2 - 0.0052 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EAU90478.2 - 0.0052 16.3 0.0 3.3 7.2 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EAU90478.2 - 0.0067 16.1 0.2 0.068 12.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EAU90478.2 - 0.008 15.4 0.0 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EAU90478.2 - 0.015 14.2 0.0 0.075 11.9 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EAU90478.2 - 0.029 14.1 0.3 0.97 9.1 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA PF00004.24 EAU90478.2 - 0.029 14.5 0.1 0.064 13.4 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EAU90478.2 - 0.03 14.5 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EAU90478.2 - 0.033 13.8 0.2 0.076 12.6 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase Mg_chelatase PF01078.16 EAU90478.2 - 0.037 13.2 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TC1 PF15063.1 EAU90478.2 - 0.047 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Thyroid cancer protein 1 DUF2075 PF09848.4 EAU90478.2 - 0.05 12.5 0.2 0.11 11.4 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EAU90478.2 - 0.088 12.2 0.0 12 5.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF605 PF04652.11 EAU90479.1 - 7.5 5.8 13.8 9.8 5.4 9.5 1.2 1 0 0 1 1 1 0 Vta1 like Carb_kinase PF01256.12 EAU90481.2 - 3.1e-48 164.1 0.0 1.2e-36 126.1 0.0 2.0 1 1 1 2 2 2 2 Carbohydrate kinase PGM_PMM_I PF02878.11 EAU90482.2 - 9.8e-38 128.7 0.1 1.5e-37 128.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EAU90482.2 - 5.5e-25 87.6 0.0 1.3e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EAU90482.2 - 1.3e-13 51.1 0.0 3.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EAU90482.2 - 1.3e-07 31.5 0.0 3.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF2460 PF09343.5 EAU90482.2 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) CybS PF05328.7 EAU90482.2 - 0.082 12.5 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CybS DUF676 PF05057.9 EAU90483.2 - 9.4e-36 123.1 0.0 1.4e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EAU90483.2 - 2.7e-05 23.8 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EAU90483.2 - 0.0075 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAU90483.2 - 0.021 14.4 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.13 EAU90483.2 - 0.16 11.2 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family SIR2 PF02146.12 EAU90484.2 - 1.6e-28 99.6 0.0 2.7e-28 98.8 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Cript PF10235.4 EAU90487.1 - 8e-22 77.4 8.4 8e-22 77.4 5.8 1.5 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT stn_TNFRSF12A PF12191.3 EAU90487.1 - 0.51 10.3 3.4 0.84 9.6 2.4 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Gin PF10764.4 EAU90487.1 - 0.89 9.3 0.1 0.89 9.3 0.0 3.0 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin C1_1 PF00130.17 EAU90487.1 - 0.92 9.2 16.2 13 5.5 0.1 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2039 PF10217.4 EAU90487.1 - 3.1 7.8 16.1 1.2 9.2 7.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.6 EAU90487.1 - 3.4 7.6 10.3 3.2 7.6 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Sgf11 PF08209.6 EAU90487.1 - 7.3 5.9 10.1 26 4.2 0.0 3.4 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) SNF2_N PF00176.18 EAU90488.2 - 1e-24 86.9 0.1 2.8e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EAU90488.2 - 2e-14 53.5 1.6 5.2e-14 52.1 0.0 2.5 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 EAU90488.2 - 0.002 17.9 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IBR PF01485.16 EAU90488.2 - 0.01 15.7 15.7 0.3 11.0 1.2 2.7 2 0 0 2 2 2 0 IBR domain PAP2 PF01569.16 EAU90489.2 - 3.2e-21 75.3 0.4 3.2e-21 75.3 0.2 1.9 2 1 0 2 2 2 1 PAP2 superfamily CTD_bind PF04818.8 EAU90490.2 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase II-binding domain. PVL_ORF50 PF07768.6 EAU90491.1 - 0.024 14.6 3.4 0.027 14.4 2.4 1.1 1 0 0 1 1 1 0 PVL ORF-50-like family DUF4131 PF13567.1 EAU90491.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) ubiquitin PF00240.18 EAU90492.1 - 6.5e-35 118.3 0.7 1.4e-34 117.2 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EAU90492.1 - 4.5e-27 93.6 1.9 9.1e-27 92.6 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EAU90492.1 - 7e-20 70.4 0.7 1.5e-19 69.4 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAU90492.1 - 1.2e-05 25.4 0.5 5e-05 23.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAU90492.1 - 0.00022 20.9 0.1 0.00035 20.3 0.0 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAU90492.1 - 0.00028 20.7 0.5 0.0006 19.6 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2207 PF09972.4 EAU90492.1 - 0.003 16.1 0.8 0.0036 15.9 0.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2407 PF10302.4 EAU90492.1 - 0.0056 16.8 0.9 0.0075 16.4 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 EAU90492.1 - 0.022 15.1 0.1 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Plexin_cytopl PF08337.7 EAU90492.1 - 0.037 12.3 3.3 0.32 9.2 0.2 2.0 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain IBR PF01485.16 EAU90492.1 - 0.042 13.7 0.7 0.067 13.0 0.5 1.4 1 0 0 1 1 1 0 IBR domain Stig1 PF04885.8 EAU90492.1 - 0.058 13.5 0.1 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2870 PF11069.3 EAU90492.1 - 0.13 12.3 1.3 0.15 12.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Rep_fac_C PF08542.6 EAU90493.1 - 8.1e-20 70.6 0.0 2.2e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EAU90493.1 - 6.7e-18 65.1 0.0 1.2e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EAU90493.1 - 2e-16 60.0 0.0 1.7e-14 53.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EAU90493.1 - 3.6e-08 32.5 0.0 7.2e-06 24.9 0.0 2.3 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 EAU90493.1 - 5.3e-08 32.5 0.1 1e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EAU90493.1 - 8.9e-08 32.0 0.0 2.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU90493.1 - 1.3e-06 28.5 0.5 0.00068 19.7 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU90493.1 - 6.2e-06 25.8 0.0 1.8e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EAU90493.1 - 1.1e-05 24.6 0.0 0.00014 21.0 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EAU90493.1 - 2.2e-05 24.1 0.1 5.4e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EAU90493.1 - 2.4e-05 23.3 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EAU90493.1 - 2.8e-05 24.1 0.0 0.00026 21.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 EAU90493.1 - 3.9e-05 23.3 0.6 0.00046 19.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAU90493.1 - 0.0006 19.5 0.1 0.0053 16.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EAU90493.1 - 0.00078 19.0 0.0 0.0018 17.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EAU90493.1 - 0.00083 18.8 0.3 0.013 14.9 0.1 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.1 EAU90493.1 - 0.0022 17.6 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAU90493.1 - 0.0041 16.6 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EAU90493.1 - 0.0051 16.2 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EAU90493.1 - 0.0072 15.7 0.0 0.048 13.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain Methyltransf_31 PF13847.1 EAU90493.1 - 0.0076 15.8 0.4 0.079 12.5 0.1 2.0 1 1 0 2 2 2 1 Methyltransferase domain T2SE PF00437.15 EAU90493.1 - 0.0082 15.0 0.1 0.069 12.0 0.0 2.1 1 1 1 2 2 2 1 Type II/IV secretion system protein SNF2_N PF00176.18 EAU90493.1 - 0.013 14.3 0.2 0.037 12.8 0.1 1.8 1 1 0 1 1 1 0 SNF2 family N-terminal domain Arch_ATPase PF01637.13 EAU90493.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EAU90493.1 - 0.023 15.4 0.0 0.052 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EAU90493.1 - 0.026 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EAU90493.1 - 0.027 14.2 0.0 0.27 11.0 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EAU90493.1 - 0.037 13.1 0.0 0.3 10.2 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EAU90493.1 - 0.042 13.2 0.3 3.2 7.0 0.0 2.6 2 1 1 3 3 3 0 AAA-like domain CobA_CobO_BtuR PF02572.10 EAU90493.1 - 0.044 13.4 0.2 2.6 7.6 0.0 2.5 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PIF1 PF05970.9 EAU90493.1 - 0.077 11.9 0.2 1.2 7.9 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase DUF2075 PF09848.4 EAU90493.1 - 0.084 11.8 0.1 0.3 10.0 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_6 PF13174.1 EAU90493.1 - 0.087 13.3 2.0 2.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_33 PF13671.1 EAU90493.1 - 0.11 12.3 0.2 0.35 10.7 0.1 1.8 2 1 0 2 2 1 0 AAA domain MobB PF03205.9 EAU90493.1 - 0.13 11.9 0.0 0.42 10.3 0.0 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Fungal_trans PF04082.13 EAU90494.2 - 2e-05 23.5 0.0 3.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU90494.2 - 0.014 15.3 1.6 0.025 14.4 1.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Paralemmin PF03285.10 EAU90494.2 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Paralemmin Cation_efflux PF01545.16 EAU90495.1 - 1.2e-71 241.0 13.2 1.4e-71 240.8 9.1 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 EAU90495.1 - 0.0025 16.8 1.1 0.0025 16.8 0.7 2.3 3 0 0 3 3 3 1 Branched-chain amino acid transport system / permease component DUF3143 PF11341.3 EAU90495.1 - 0.038 13.8 0.2 6.2 6.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3143) DUF457 PF04307.9 EAU90495.1 - 1.3 8.3 7.4 0.62 9.3 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Zw10 PF06248.8 EAU90496.1 - 1.3e-22 79.6 3.3 7.7e-16 57.3 1.5 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EAU90496.1 - 1.5e-11 43.9 0.0 3.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Med9 PF07544.8 EAU90496.1 - 0.03 14.0 3.1 0.63 9.8 0.1 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 EAU90496.1 - 0.21 11.3 2.4 0.9 9.3 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EAU90498.1 - 4.8e-10 38.9 1.9 0.74 9.7 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat hGDE_N PF14699.1 EAU90499.1 - 0.049 13.4 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme DnaJ PF00226.26 EAU90500.2 - 1.1e-26 92.3 0.7 1.7e-26 91.6 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EAU90500.2 - 9.7e-15 54.7 0.0 4.1e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1977) F-box-like PF12937.2 EAU90501.1 - 1.2e-05 24.8 0.1 2.6e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU90501.1 - 1.7e-05 24.3 0.2 3.4e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 EAU90501.1 - 4e-05 23.3 3.8 0.00015 21.5 2.6 2.0 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EAU90501.1 - 0.027 14.3 0.1 0.085 12.8 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90501.1 - 0.049 13.2 0.7 0.11 12.2 0.5 1.6 1 0 0 1 1 1 0 TPR repeat MBOAT PF03062.14 EAU90502.2 - 5.3e-30 104.6 14.6 5.3e-30 104.6 10.1 2.7 2 2 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EAU90502.2 - 0.00036 20.5 5.5 0.00077 19.4 2.4 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family ORC4_C PF14629.1 EAU90502.2 - 0.04 13.2 0.2 0.083 12.2 0.2 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Levi_coat PF01819.12 EAU90502.2 - 0.18 11.3 0.3 0.34 10.4 0.2 1.4 1 0 0 1 1 1 0 Levivirus coat protein Clr2 PF10383.4 EAU90503.2 - 0.00077 19.4 0.0 0.25 11.3 0.0 4.1 4 1 0 4 4 4 1 Transcription-silencing protein Clr2 KAR9 PF08580.5 EAU90504.2 - 5.6e-08 31.5 0.0 5.6e-08 31.5 0.0 4.9 3 2 1 4 4 4 2 Yeast cortical protein KAR9 PAP2 PF01569.16 EAU90504.2 - 0.071 12.7 0.2 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 PAP2 superfamily MscS_porin PF12795.2 EAU90504.2 - 0.7 9.1 6.5 2.1 7.6 1.2 2.8 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain RIC3 PF15361.1 EAU90504.2 - 7.4 6.7 7.1 1.2 9.3 0.1 3.4 3 1 1 4 4 4 0 Resistance to inhibitors of cholinesterase homologue 3 TPR_19 PF14559.1 EAU90505.2 - 8e-11 42.1 3.4 2.3e-06 27.8 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90505.2 - 1.9e-10 40.2 1.6 6.1e-07 28.9 0.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 EAU90505.2 - 2.3e-10 40.1 5.0 0.017 15.7 0.0 4.8 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU90505.2 - 1.3e-09 38.4 2.9 3.4e-07 30.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90505.2 - 2.6e-07 30.0 0.3 0.011 15.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU90505.2 - 3.4e-07 29.5 0.2 0.051 13.3 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU90505.2 - 2.8e-06 26.6 0.4 0.11 12.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU90505.2 - 7.6e-05 22.5 0.7 0.0019 18.1 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAU90505.2 - 0.00013 21.8 0.2 0.041 14.0 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU90505.2 - 0.00037 20.5 0.0 0.031 14.3 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EAU90505.2 - 0.00075 19.0 0.0 0.29 10.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EAU90505.2 - 0.0011 18.1 0.7 0.0097 15.1 0.1 2.1 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_20 PF14561.1 EAU90505.2 - 0.0015 18.5 3.1 0.37 10.9 0.2 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 EAU90505.2 - 0.0019 18.1 4.1 0.15 11.9 1.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAU90505.2 - 0.002 17.9 2.8 0.15 12.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAU90505.2 - 0.0037 17.6 0.6 3.1 8.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EAU90505.2 - 0.027 14.8 2.6 46 4.8 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Tropomyosin_1 PF12718.2 EAU90506.1 - 2.7e-06 27.2 1.0 3.8e-06 26.8 0.7 1.1 1 0 0 1 1 1 1 Tropomyosin like APG17 PF04108.7 EAU90506.1 - 0.0005 19.0 0.1 0.00075 18.4 0.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg17 IncA PF04156.9 EAU90506.1 - 0.0051 16.4 3.4 0.01 15.4 2.4 1.5 1 1 0 1 1 1 1 IncA protein KxDL PF10241.4 EAU90506.1 - 0.0082 16.0 1.3 0.032 14.1 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein WEMBL PF05701.6 EAU90506.1 - 0.009 14.5 0.7 0.011 14.2 0.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 EAU90506.1 - 0.01 13.5 1.9 0.013 13.2 1.3 1.0 1 0 0 1 1 1 0 Myosin tail GAS PF13851.1 EAU90506.1 - 0.013 14.7 0.8 0.018 14.2 0.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EAU90506.1 - 0.03 14.1 1.1 0.2 11.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 EAU90506.1 - 0.036 13.7 3.3 0.1 12.3 2.3 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Rop-like PF05082.8 EAU90506.1 - 0.049 13.0 2.0 0.2 11.1 0.3 2.3 1 1 1 2 2 2 0 Rop-like MIF4G_like_2 PF09090.6 EAU90506.1 - 0.05 12.8 0.3 0.06 12.5 0.2 1.1 1 0 0 1 1 1 0 MIF4G like Seryl_tRNA_N PF02403.17 EAU90506.1 - 0.055 13.4 1.5 0.12 12.3 1.1 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.15 EAU90506.1 - 0.088 12.5 2.2 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit ApoLp-III PF07464.6 EAU90506.1 - 0.098 12.6 0.4 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Spc7 PF08317.6 EAU90506.1 - 0.1 11.2 0.9 0.13 10.9 0.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YlqD PF11068.3 EAU90506.1 - 0.13 12.3 1.1 0.2 11.7 0.8 1.2 1 0 0 1 1 1 0 YlqD protein Rootletin PF15035.1 EAU90506.1 - 0.13 12.1 3.7 0.38 10.6 2.6 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Tropomyosin PF00261.15 EAU90506.1 - 0.3 10.1 5.5 5.2 6.0 3.8 2.0 1 1 0 1 1 1 0 Tropomyosin Vps5 PF09325.5 EAU90507.2 - 3.5e-56 190.0 16.9 2.5e-54 184.0 11.7 2.2 1 1 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EAU90507.2 - 5.4e-25 87.3 0.1 6.3e-24 83.9 0.0 2.3 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 EAU90507.2 - 0.00024 20.4 0.9 0.0004 19.7 0.6 1.3 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein BAR PF03114.13 EAU90507.2 - 0.02 14.4 9.3 0.23 10.9 6.4 2.1 1 1 0 1 1 1 0 BAR domain Arfaptin PF06456.8 EAU90507.2 - 0.13 11.5 4.7 6.9 5.9 3.2 2.2 1 1 0 1 1 1 0 Arfaptin-like domain DNA_pack_N PF02500.10 EAU90507.2 - 0.81 9.1 3.5 1.1 8.7 1.1 1.9 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus DWNN PF08783.6 EAU90508.1 - 9.4e-26 89.5 1.1 1.3e-25 89.1 0.1 1.8 2 0 0 2 2 1 1 DWNN domain zf-CCHC_2 PF13696.1 EAU90508.1 - 1.2e-07 31.0 1.5 2.9e-07 29.8 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 EAU90508.1 - 5e-06 26.3 0.0 4.9e-05 23.2 0.0 2.5 1 1 1 2 2 2 1 U-box domain zf-CCHC PF00098.18 EAU90508.1 - 2.2e-05 24.1 2.0 2.2e-05 24.1 1.4 1.6 2 0 0 2 2 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EAU90508.1 - 0.00066 19.3 0.4 0.0018 17.9 0.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EAU90508.1 - 0.0016 18.4 9.2 0.0016 18.4 6.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CCDC-167 PF15188.1 EAU90508.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2361 PF10153.4 EAU90508.1 - 0.094 12.9 1.5 0.18 11.9 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) zf-C3HC4_3 PF13920.1 EAU90508.1 - 0.35 10.5 11.8 0.03 13.9 4.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 EAU90508.1 - 1.5 8.3 6.0 0.12 11.8 0.3 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-Nse PF11789.3 EAU90508.1 - 1.8 8.1 6.9 4.2 6.9 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EAU90508.1 - 2.2 8.1 15.3 0.048 13.4 5.9 1.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EAU90508.1 - 2.5 7.9 13.0 0.29 10.8 5.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU90508.1 - 2.6 7.8 9.5 5.8 6.6 6.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU90508.1 - 3.6 7.5 9.1 8.7 6.3 6.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ERG4_ERG24 PF01222.12 EAU90509.2 - 1.5e-125 419.1 28.2 1.7e-125 418.9 19.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EAU90509.2 - 2.3e-06 27.0 3.1 4.6e-06 26.0 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EAU90509.2 - 0.00026 21.1 0.2 0.00026 21.1 0.2 2.9 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FAT PF02259.18 EAU90510.2 - 2.9e-113 378.4 3.2 2.9e-113 378.4 2.2 2.6 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 EAU90510.2 - 1e-57 195.3 0.4 1.9e-57 194.4 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EAU90510.2 - 6.4e-48 162.7 1.6 7.5e-47 159.2 0.3 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EAU90510.2 - 3.5e-38 129.7 1.3 2.3e-37 127.1 0.0 3.2 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EAU90510.2 - 4.6e-22 78.1 11.3 0.011 15.9 0.1 10.7 8 3 2 10 10 10 4 HEAT repeats FATC PF02260.15 EAU90510.2 - 2.9e-16 58.6 0.4 7.1e-16 57.3 0.3 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EAU90510.2 - 4.3e-14 51.2 10.3 0.024 14.6 0.1 11.0 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EAU90510.2 - 1.2e-10 41.5 19.7 0.001 19.5 0.7 10.5 9 1 2 11 11 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EAU90510.2 - 4.2e-10 39.8 0.0 2.1 8.8 0.0 7.9 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region TPR_19 PF14559.1 EAU90510.2 - 2.5e-06 27.7 0.0 0.0085 16.4 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat CLASP_N PF12348.3 EAU90510.2 - 5.3e-05 22.6 2.8 0.16 11.3 0.0 5.0 5 0 0 5 5 5 2 CLASP N terminal TPR_7 PF13176.1 EAU90510.2 - 0.00038 20.0 1.7 0.1 12.4 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90510.2 - 0.00088 19.0 1.9 8.5 6.5 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU90510.2 - 0.0025 18.2 1.7 0.5 11.1 0.0 5.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90510.2 - 0.0028 17.2 4.1 0.064 12.9 0.0 4.1 4 0 0 4 4 4 1 TPR repeat TRI12 PF06609.8 EAU90510.2 - 0.21 9.7 0.0 0.43 8.7 0.0 1.4 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Actin PF00022.14 EAU90511.2 - 1.6e-30 105.8 0.0 2.5e-13 49.2 0.0 3.0 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 EAU90511.2 - 0.0032 16.1 0.1 0.065 11.8 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein zf-C2H2 PF00096.21 EAU90513.2 - 0.022 15.0 0.4 0.11 12.8 0.3 2.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type RCC1_2 PF13540.1 EAU90514.2 - 2e-15 55.8 21.5 1.4e-06 27.7 0.3 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EAU90514.2 - 3e-15 56.1 8.3 0.0018 18.4 0.0 6.5 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EAU90514.2 - 3.7e-06 26.5 0.8 8.4e-06 25.4 0.5 1.7 1 0 0 1 1 1 1 F-box-like DUF1921 PF09081.5 EAU90514.2 - 0.032 14.1 4.4 0.036 14.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1921) F-box PF00646.28 EAU90514.2 - 0.053 13.1 1.7 0.2 11.3 1.2 2.0 1 1 0 1 1 1 0 F-box domain Peptidase_M28 PF04389.12 EAU90516.1 - 4e-28 98.3 0.0 6.5e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAU90516.1 - 6.4e-09 35.5 0.0 8.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EAU90516.1 - 0.0051 15.6 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase FGGY_C PF02782.11 EAU90517.1 - 1.9e-26 92.9 0.1 8.8e-25 87.4 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EAU90517.1 - 2.7e-25 89.1 0.0 1.9e-16 60.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FYRC PF05965.9 EAU90517.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 F/Y rich C-terminus Polysacc_synt PF01943.12 EAU90519.1 - 0.052 12.7 0.3 0.081 12.1 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NUDIX PF00293.23 EAU90520.2 - 1.9e-07 30.7 0.0 4.7e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Aa_trans PF01490.13 EAU90521.2 - 2.1e-86 289.9 19.0 2.4e-86 289.7 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EAU90521.2 - 6.5e-05 21.9 14.9 6.5e-05 21.9 10.3 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family TspO_MBR PF03073.10 EAU90521.2 - 0.0046 16.4 0.3 0.0046 16.4 0.2 2.1 2 0 0 2 2 2 1 TspO/MBR family Internalin_N PF12354.3 EAU90521.2 - 0.47 10.1 3.3 1.8 8.2 0.5 3.0 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal SUZ PF12752.2 EAU90522.2 - 9.3e-16 58.1 1.3 9.3e-16 58.1 0.9 3.5 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EAU90522.2 - 0.0028 17.3 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 R3H domain RNA_pol_Rpb4 PF03874.11 EAU90524.1 - 1e-21 77.0 0.2 1.3e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2666 PF10869.3 EAU90524.1 - 0.046 13.7 0.1 0.15 12.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) PseudoU_synth_1 PF01416.15 EAU90525.1 - 1.7e-21 76.6 0.0 6.8e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase CDC27 PF09507.5 EAU90526.1 - 6.6e-34 117.8 87.0 3.3e-30 105.6 60.3 3.4 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 OTT_1508_deam PF14441.1 EAU90528.2 - 0.0028 17.4 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase SF3b1 PF08920.5 EAU90529.1 - 3.7e-22 78.9 13.4 9.5e-21 74.3 9.3 3.2 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EAU90529.1 - 5.6e-13 48.9 11.2 0.0001 22.4 0.0 7.8 4 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EAU90529.1 - 2.9e-10 40.3 10.7 0.0052 17.2 0.0 8.5 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 EAU90529.1 - 1.5e-09 37.0 12.9 0.0084 16.1 0.1 9.6 11 0 0 11 11 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EAU90529.1 - 6.8e-08 32.7 1.9 0.14 12.5 0.0 5.3 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EAU90529.1 - 4.1e-07 28.7 2.9 0.018 13.4 0.1 3.4 2 1 0 3 3 3 3 Adaptin N terminal region NUC173 PF08161.7 EAU90529.1 - 0.00025 20.4 0.5 7.1 5.9 0.0 4.7 4 1 1 5 5 5 2 NUC173 domain CLASP_N PF12348.3 EAU90529.1 - 0.0015 17.9 1.6 2.7 7.3 0.0 3.8 3 1 1 4 4 4 2 CLASP N terminal Cnd1 PF12717.2 EAU90529.1 - 0.057 13.2 5.9 41 3.9 0.0 5.2 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EAU90529.1 - 0.084 12.7 0.4 9.7 6.1 0.0 4.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2951 PF11166.3 EAU90529.1 - 0.36 10.7 5.2 1.2 8.9 3.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Adaptin_N PF01602.15 EAU90530.1 - 1.7e-142 475.4 9.0 2e-142 475.2 6.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EAU90530.1 - 2.4e-21 76.2 0.1 5.8e-21 74.9 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EAU90530.1 - 5.2e-07 29.8 2.5 0.37 11.1 0.0 4.7 3 2 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EAU90530.1 - 9.8e-05 22.2 4.1 0.017 14.9 0.8 3.1 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EAU90530.1 - 0.0011 18.8 6.0 8.4 6.7 0.1 6.1 6 0 0 6 6 6 1 HEAT repeat TIP120 PF08623.5 EAU90530.1 - 0.011 15.3 0.4 0.011 15.3 0.3 2.2 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Arm PF00514.18 EAU90530.1 - 0.35 10.7 3.7 90 3.1 0.0 5.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF805 PF05656.9 EAU90531.2 - 0.072 12.9 1.6 0.12 12.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Peptidase_S10 PF00450.17 EAU90532.2 - 1.7e-50 172.4 0.0 4.6e-50 170.9 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase GCFC PF07842.7 EAU90533.2 - 2.9e-80 269.5 11.1 4.8e-80 268.8 7.7 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EAU90533.2 - 4.7e-21 74.9 17.0 4.7e-21 74.9 11.8 3.0 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EAU90533.2 - 3.4e-13 49.1 2.4 3.4e-13 49.1 1.7 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EAU90533.2 - 1.3e-06 28.1 0.8 1.3e-06 28.1 0.5 3.2 2 1 0 2 2 2 1 DExH-box splicing factor binding site OmpH PF03938.9 EAU90533.2 - 0.48 10.3 13.5 2.4 8.0 0.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.27 EAU90534.2 - 5.7e-10 38.6 0.0 0.0074 16.1 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ELMO_CED12 PF04727.8 EAU90535.2 - 4.9e-28 97.7 0.0 8.4e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EAU90535.2 - 3.9e-16 59.1 0.2 6.2e-11 42.2 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3361) FERM_N PF09379.5 EAU90535.2 - 0.068 13.2 0.1 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 FERM N-terminal domain MTHFR PF02219.12 EAU90536.2 - 1.6e-108 362.1 0.0 2.2e-108 361.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF202 PF02656.10 EAU90537.1 - 6.4e-05 23.0 1.6 0.00021 21.4 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) CopD PF05425.8 EAU90537.1 - 0.011 15.8 3.4 0.024 14.8 0.1 2.0 2 0 0 2 2 2 0 Copper resistance protein D MttA_Hcf106 PF02416.11 EAU90537.1 - 0.08 12.0 1.0 2.8 7.1 0.2 2.6 3 0 0 3 3 3 0 mttA/Hcf106 family Pkinase PF00069.20 EAU90539.1 - 3.2e-74 249.3 0.0 4.8e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU90539.1 - 5e-37 127.3 0.0 1e-36 126.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU90539.1 - 0.0019 17.2 0.0 0.0049 15.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU90539.1 - 0.0077 15.3 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU90539.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4391 PF14335.1 EAU90539.1 - 0.12 11.7 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) Choline_kinase PF01633.15 EAU90539.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Dynein_light PF01221.13 EAU90540.2 - 6.4e-41 138.2 0.3 7.6e-41 138.0 0.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 EAU90540.2 - 0.13 12.5 0.1 0.21 11.8 0.0 1.4 1 1 0 1 1 1 0 Ground-like domain He_PIG PF05345.7 EAU90541.1 - 2.9e-11 43.2 13.8 2e-07 30.9 3.2 4.9 4 0 0 4 4 4 3 Putative Ig domain HEAT_EZ PF13513.1 EAU90542.2 - 3.5e-20 71.8 17.0 0.00035 20.9 0.0 11.6 10 2 3 13 13 13 4 HEAT-like repeat HEAT PF02985.17 EAU90542.2 - 1.9e-17 61.6 17.2 0.0004 20.2 0.0 9.6 12 0 0 12 12 9 3 HEAT repeat HEAT_2 PF13646.1 EAU90542.2 - 1.7e-15 57.0 11.2 0.0018 18.5 0.6 7.7 4 1 4 8 8 7 7 HEAT repeats IBN_N PF03810.14 EAU90542.2 - 2.4e-08 33.7 3.3 1.2e-07 31.4 0.3 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EAU90542.2 - 1.8e-06 26.5 0.1 0.086 11.1 0.0 3.7 3 1 0 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.3 EAU90542.2 - 1.8e-05 24.2 0.8 7.3 5.8 0.0 5.0 4 1 1 5 5 5 3 CLASP N terminal Ipi1_N PF12333.3 EAU90542.2 - 6.6e-05 22.8 0.0 2.3 8.2 0.0 4.9 4 1 1 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation Xpo1 PF08389.7 EAU90542.2 - 0.00031 20.6 0.0 1 9.2 0.0 4.5 4 1 0 4 4 4 1 Exportin 1-like protein Vac14_Fab1_bd PF12755.2 EAU90542.2 - 0.00061 20.1 0.1 1.2 9.5 0.0 5.2 6 1 1 7 7 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EAU90542.2 - 0.05 13.4 0.0 27 4.5 0.0 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 MOR2-PAG1_C PF14225.1 EAU90542.2 - 0.081 12.6 0.2 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Cell morphogenesis C-terminal UME PF08064.8 EAU90542.2 - 0.096 12.6 0.0 23 4.9 0.1 3.4 3 0 0 3 3 3 0 UME (NUC010) domain RasGEF_N_2 PF14663.1 EAU90542.2 - 0.16 11.8 0.5 20 5.1 0.2 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DHO_dh PF01180.16 EAU90543.1 - 3.4e-97 324.9 0.0 4.2e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 EAU90543.1 - 0.0012 18.0 0.1 0.0042 16.2 0.0 1.9 2 0 0 2 2 2 1 Nitronate monooxygenase BTB PF00651.26 EAU90544.2 - 8.5e-05 22.5 0.0 0.00026 20.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Herpes_IE2_3 PF03361.9 EAU90544.2 - 0.14 11.5 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Salp15 PF12115.3 EAU90545.1 - 0.49 10.6 3.7 4.5 7.5 0.3 2.3 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF2360 PF10152.4 EAU90545.1 - 1.2 9.3 6.7 1.7 8.8 0.5 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Sugar_tr PF00083.19 EAU90547.2 - 9.2e-92 307.9 13.1 4.7e-91 305.6 8.1 1.9 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EAU90547.2 - 3e-29 101.8 23.1 3.8e-29 101.5 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1156 PF06634.7 EAU90547.2 - 0.0068 16.1 0.4 1.9 8.2 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1156) AIP3 PF03915.8 EAU90549.2 - 2.4e-106 356.1 9.1 4.8e-106 355.1 6.3 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EAU90549.2 - 0.25 10.7 4.0 0.66 9.3 0.9 2.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 EAU90549.2 - 0.71 9.6 9.6 0.69 9.7 2.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EAU90549.2 - 0.74 10.2 13.8 4.7 7.6 0.1 4.5 4 1 1 5 5 5 0 Syntaxin 6, N-terminal Prominin PF05478.6 EAU90549.2 - 2.3 5.6 7.0 0.85 7.0 1.1 2.3 2 1 0 2 2 2 0 Prominin TBPIP PF07106.8 EAU90549.2 - 3.1 7.3 21.7 0.13 11.7 3.1 4.2 3 1 1 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Metallophos PF00149.23 EAU90550.2 - 5.8e-08 32.3 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU90550.2 - 1e-05 25.3 0.0 3.2e-05 23.8 0.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.15 EAU90551.1 - 5.9e-10 38.9 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Glucan_synthase PF02364.10 EAU90551.1 - 0.099 10.4 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Mac PF12464.3 EAU90551.1 - 0.69 9.9 4.6 3.2 7.8 0.2 3.8 3 2 0 3 3 3 0 Maltose acetyltransferase LRR_4 PF12799.2 EAU90552.1 - 3.7e-13 48.7 5.3 1.9e-08 33.7 0.8 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU90552.1 - 1.9e-06 27.5 3.0 1.4e-05 24.7 0.6 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EAU90552.1 - 2.8e-05 23.5 3.2 0.13 12.4 0.2 4.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EAU90552.1 - 0.00013 21.5 0.9 1.2 9.6 0.2 3.8 3 0 0 3 3 3 2 Leucine rich repeat zf-H2C2_2 PF13465.1 EAU90553.1 - 6.8e-25 86.0 39.1 2.4e-07 30.6 0.5 8.0 9 0 0 9 9 9 4 Zinc-finger double domain zf-C2H2 PF00096.21 EAU90553.1 - 6.1e-23 79.7 45.5 3.6e-06 26.9 1.4 8.5 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU90553.1 - 3e-16 58.4 36.7 0.00068 19.7 1.8 8.2 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EAU90553.1 - 1.3e-07 31.2 15.1 0.018 14.9 0.2 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU90553.1 - 5.8e-06 26.2 10.5 0.0074 16.4 0.3 5.0 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EAU90553.1 - 0.0061 16.2 1.9 0.0061 16.2 1.4 4.8 5 0 0 5 5 5 1 BED zinc finger zf-C2H2_2 PF12756.2 EAU90553.1 - 0.02 15.0 20.2 0.67 10.0 0.3 4.3 3 2 1 4 4 3 0 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 EAU90553.1 - 0.06 12.7 0.9 0.2 11.1 0.0 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.1 EAU90553.1 - 0.075 13.2 24.9 0.86 9.9 2.6 6.4 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-AN1 PF01428.11 EAU90553.1 - 0.11 12.3 6.7 5 7.0 0.3 3.6 2 1 0 2 2 2 0 AN1-like Zinc finger zf-met2 PF12907.2 EAU90553.1 - 0.13 12.2 6.1 1.7 8.6 2.5 3.2 2 0 0 2 2 2 0 Zinc-binding zf-met PF12874.2 EAU90553.1 - 0.26 11.5 21.3 0.71 10.1 1.1 5.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 EAU90553.1 - 0.71 9.4 9.1 0.095 12.2 2.7 2.3 2 0 0 2 2 2 0 InsA N-terminal domain zf-Di19 PF05605.7 EAU90553.1 - 7.6 6.7 22.6 0.24 11.5 0.5 4.7 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding CTP_transf_2 PF01467.21 EAU90554.2 - 3.9e-13 49.7 0.0 5.9e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase FAD_binding_3 PF01494.14 EAU90555.2 - 4.9e-32 111.3 0.0 6.8e-28 97.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 EAU90556.2 - 3.8e-39 134.7 0.0 8.5e-30 104.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EAU90556.2 - 1.1e-05 24.7 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EAU90556.2 - 1.4e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EAU90556.2 - 3e-05 24.3 0.0 0.00065 20.0 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU90556.2 - 3.8e-05 22.7 0.0 7.1e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAU90556.2 - 0.00025 20.0 0.1 0.00051 19.0 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EAU90556.2 - 0.0009 17.8 0.0 0.0013 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EAU90556.2 - 0.00098 19.0 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU90556.2 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EAU90556.2 - 0.026 13.4 0.1 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EAU90556.2 - 0.073 11.9 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EAU90556.2 - 0.078 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EAU90556.2 - 0.16 11.6 0.0 0.4 10.3 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EAU90557.2 - 6.6e-48 163.5 0.0 8.8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF2962 PF11176.3 EAU90558.2 - 1.4e-35 122.1 3.9 1.6e-35 121.9 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Death PF00531.17 EAU90558.2 - 0.012 15.4 0.3 0.026 14.2 0.0 1.7 2 0 0 2 2 2 0 Death domain MOZART1 PF12554.3 EAU90559.1 - 1.5e-23 82.0 0.4 1.8e-23 81.7 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 EAU90559.1 - 0.0024 17.4 0.0 0.0026 17.3 0.0 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Zds_C PF08632.5 EAU90560.2 - 3e-22 77.7 0.7 5.2e-22 77.0 0.5 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term P34-Arc PF04045.9 EAU90562.2 - 1.4e-103 345.4 0.0 1.6e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Sec6 PF06046.8 EAU90564.2 - 3.9e-148 494.0 7.2 5.6e-148 493.5 5.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Lipase_GDSL PF00657.17 EAU90564.2 - 0.15 11.8 0.1 0.61 9.8 0.0 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF1788 PF08747.6 EAU90564.2 - 2.8 7.8 6.3 27 4.6 0.1 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1788) TCTP PF00838.12 EAU90564.2 - 3.5 7.6 9.6 3.1 7.7 0.1 3.5 4 0 0 4 4 4 0 Translationally controlled tumour protein FAD_binding_3 PF01494.14 EAU90565.2 - 1.6e-16 60.3 0.0 2.9e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EAU90565.2 - 1.8e-05 23.7 0.0 3.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Turandot PF07240.6 EAU90567.2 - 0.0033 16.8 0.1 0.0075 15.7 0.1 1.5 1 0 0 1 1 1 1 Stress-inducible humoral factor Turandot Med9 PF07544.8 EAU90567.2 - 0.026 14.2 2.4 0.062 13.0 0.2 2.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EAU90567.2 - 0.03 13.9 4.1 0.13 11.8 0.4 2.3 2 0 0 2 2 2 0 IncA protein ApoO PF09769.4 EAU90567.2 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Apolipoprotein O COG2 PF06148.6 EAU90567.2 - 0.041 13.7 0.7 1 9.2 0.1 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 UBN2_2 PF14227.1 EAU90567.2 - 0.051 13.1 0.3 0.5 9.9 0.1 2.1 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF1664 PF07889.7 EAU90567.2 - 0.056 13.2 0.8 0.76 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.6 EAU90567.2 - 0.089 11.2 3.3 0.13 10.7 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Nif11 PF07862.6 EAU90567.2 - 0.12 12.2 0.5 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function DUF2659 PF10858.3 EAU90567.2 - 0.16 11.3 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) PIF1 PF05970.9 EAU90568.2 - 1.1e-71 241.7 0.0 7.9e-70 235.6 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EAU90568.2 - 4.5e-46 156.9 0.0 9.2e-46 155.8 0.0 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.1 EAU90568.2 - 1.4e-09 37.8 0.0 4.3e-09 36.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EAU90568.2 - 2.4e-06 27.2 0.3 5.7e-05 22.7 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain Herpes_Helicase PF02689.9 EAU90568.2 - 2.8e-05 22.0 0.0 0.021 12.6 0.0 2.1 2 0 0 2 2 2 2 Helicase Viral_helicase1 PF01443.13 EAU90568.2 - 2.9e-05 23.7 0.2 0.026 14.0 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EAU90568.2 - 0.00015 20.8 0.0 0.00059 18.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EAU90568.2 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU90568.2 - 0.0024 18.0 0.0 0.0064 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU90568.2 - 0.0039 18.0 0.6 0.026 15.3 0.0 2.8 3 0 0 3 3 1 1 AAA domain MobB PF03205.9 EAU90568.2 - 0.0043 16.7 0.1 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EAU90568.2 - 0.014 15.1 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EAU90568.2 - 0.015 15.4 0.1 0.054 13.6 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Phage_GPA PF05840.8 EAU90568.2 - 0.018 13.7 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) UvrD_C_2 PF13538.1 EAU90568.2 - 0.019 15.1 0.0 0.056 13.5 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 EAU90568.2 - 0.02 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EAU90568.2 - 0.044 13.6 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EAU90568.2 - 0.045 13.3 0.2 0.25 10.9 0.0 2.3 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EAU90568.2 - 0.048 13.3 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EAU90568.2 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 NTPase CbiA PF01656.18 EAU90568.2 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.1 EAU90568.2 - 0.087 13.1 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EAU90568.2 - 0.09 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.4 EAU90568.2 - 0.11 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EAU90568.2 - 0.12 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Thymidylate_kin PF02223.12 EAU90568.2 - 0.14 11.4 0.0 0.36 10.1 0.0 1.7 1 0 0 1 1 1 0 Thymidylate kinase Sigma54_activat PF00158.21 EAU90568.2 - 0.22 10.9 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EAU90568.2 - 0.26 10.8 0.1 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF605 PF04652.11 EAU90569.1 - 0.69 9.2 14.6 1.1 8.5 10.1 1.4 1 0 0 1 1 1 0 Vta1 like Mito_fiss_reg PF05308.6 EAU90576.2 - 0.0033 16.8 1.1 0.0033 16.8 0.8 4.7 3 1 2 5 5 5 1 Mitochondrial fission regulator DUF572 PF04502.8 EAU90576.2 - 0.017 14.3 0.4 0.026 13.7 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ELYS PF13934.1 EAU90577.2 - 2.4e-51 174.6 0.0 3.2e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Mito_carr PF00153.22 EAU90579.1 - 1.9e-33 114.0 7.2 2.1e-19 68.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4514 PF14986.1 EAU90579.1 - 0.025 14.4 0.2 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) DHBP_synthase PF00926.14 EAU90580.1 - 4.9e-78 260.8 0.1 5.6e-78 260.6 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase zf-RING_2 PF13639.1 EAU90581.2 - 2.6e-05 23.9 2.8 0.00078 19.2 0.4 2.5 2 0 0 2 2 2 1 Ring finger domain PQ-loop PF04193.9 EAU90581.2 - 0.0012 18.3 0.4 0.003 17.0 0.3 1.7 1 0 0 1 1 1 1 PQ loop repeat zf-rbx1 PF12678.2 EAU90581.2 - 0.049 13.7 3.9 0.24 11.5 2.7 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EAU90581.2 - 0.1 12.4 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EAU90581.2 - 0.12 12.0 3.1 0.093 12.4 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) EI24 PF07264.6 EAU90581.2 - 0.13 11.6 7.5 0.12 11.7 1.6 2.2 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) zf-C3HC4_2 PF13923.1 EAU90581.2 - 0.21 11.6 4.3 0.087 12.8 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EAU90581.2 - 0.23 11.4 2.4 0.91 9.5 0.5 2.5 3 0 0 3 3 3 0 FANCL C-terminal domain DUF805 PF05656.9 EAU90581.2 - 2.7 7.8 6.5 0.62 9.8 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Tyrosinase PF00264.15 EAU90582.2 - 3e-26 92.9 0.0 1.4e-25 90.7 0.0 1.9 1 1 1 2 2 2 1 Common central domain of tyrosinase Nnf1 PF03980.9 EAU90582.2 - 1.9e-10 40.7 3.7 4.9e-10 39.3 2.5 1.7 1 0 0 1 1 1 1 Nnf1 DUF904 PF06005.7 EAU90582.2 - 0.0046 17.2 2.9 0.0094 16.2 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) CENP-F_leu_zip PF10473.4 EAU90582.2 - 0.011 15.6 6.0 0.021 14.6 4.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_I PF06008.9 EAU90582.2 - 0.011 15.0 5.7 0.019 14.2 4.0 1.3 1 0 0 1 1 1 0 Laminin Domain I SNARE PF05739.14 EAU90582.2 - 0.034 13.8 5.2 0.027 14.1 2.3 1.8 2 0 0 2 2 1 0 SNARE domain CASP_C PF08172.7 EAU90582.2 - 0.057 12.4 2.5 0.089 11.7 1.8 1.2 1 0 0 1 1 1 0 CASP C terminal DUF948 PF06103.6 EAU90582.2 - 0.063 13.1 0.4 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2968 PF11180.3 EAU90582.2 - 0.076 12.3 3.5 0.14 11.5 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) V_ATPase_I PF01496.14 EAU90582.2 - 0.35 8.6 2.4 0.45 8.3 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family STAT_alpha PF01017.15 EAU90582.2 - 0.4 10.3 7.4 0.25 11.0 2.7 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF1664 PF07889.7 EAU90582.2 - 0.41 10.4 2.9 0.18 11.5 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EAU90582.2 - 0.45 10.0 5.1 0.69 9.4 3.5 1.3 1 0 0 1 1 1 0 IncA protein NTR2 PF15458.1 EAU90582.2 - 0.51 9.5 8.7 0.6 9.2 5.5 1.5 1 1 0 1 1 1 0 Nineteen complex-related protein 2 DUF972 PF06156.8 EAU90582.2 - 1.1 9.6 5.8 1.6 9.0 3.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Prefoldin PF02996.12 EAU90582.2 - 7.5 6.2 8.0 3.4 7.3 3.7 1.8 2 0 0 2 2 2 0 Prefoldin subunit DUF4556 PF15094.1 EAU90583.2 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Leo1 PF04004.8 EAU90584.2 - 3.5e-55 186.3 0.6 6.6e-55 185.4 0.4 1.5 1 0 0 1 1 1 1 Leo1-like protein Atx10homo_assoc PF09759.4 EAU90585.2 - 6.3e-09 35.4 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Ufd2P_core PF10408.4 EAU90585.2 - 0.017 13.4 0.0 0.022 13.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core GBV-C_env PF12786.2 EAU90585.2 - 0.15 10.5 1.3 0.22 9.9 0.1 1.7 2 0 0 2 2 2 0 GB virus C genotype envelope BRAP2 PF07576.7 EAU90587.2 - 5.4e-22 77.4 0.0 1.1e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EAU90587.2 - 4e-20 71.6 5.2 9.3e-20 70.5 3.6 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EAU90587.2 - 1.2e-08 34.6 9.8 1.2e-08 34.6 6.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EAU90587.2 - 1.1e-05 24.9 7.5 2.8e-05 23.6 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU90587.2 - 0.00014 21.4 6.7 0.00014 21.4 4.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EAU90587.2 - 0.00023 21.1 4.0 0.00023 21.1 2.8 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EAU90587.2 - 0.00059 19.8 9.3 0.00059 19.8 6.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90587.2 - 0.00059 19.5 6.6 0.00059 19.5 4.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EAU90587.2 - 0.0073 16.1 3.7 0.015 15.1 2.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_6 PF14259.1 EAU90587.2 - 0.035 14.0 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 EAU90587.2 - 0.11 12.0 6.2 0.26 10.8 4.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EAU90587.2 - 0.13 12.0 4.0 0.3 10.8 1.4 2.4 1 1 1 2 2 2 0 RING-type zinc-finger AAA_13 PF13166.1 EAU90587.2 - 0.48 8.8 12.6 0.68 8.3 8.7 1.1 1 0 0 1 1 1 0 AAA domain SGT1 PF07093.6 EAU90587.2 - 0.68 8.2 11.1 0.97 7.7 7.7 1.1 1 0 0 1 1 1 0 SGT1 protein DUF1664 PF07889.7 EAU90587.2 - 1.1 9.0 4.0 2.5 7.9 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TerY-C PF15616.1 EAU90587.2 - 9.5 6.1 15.0 0.32 10.9 3.0 2.5 1 1 1 2 2 2 0 TerY-C metal binding domain Polysacc_deac_1 PF01522.16 EAU90589.1 - 4.8e-20 71.4 0.2 1e-19 70.3 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase SH3_1 PF00018.23 EAU90591.1 - 1.6e-18 65.8 3.2 5.2e-09 35.3 0.1 2.9 2 1 0 2 2 2 2 SH3 domain SAM_1 PF00536.25 EAU90591.1 - 2.2e-15 56.5 0.1 4.8e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EAU90591.1 - 2.3e-14 52.9 0.0 4.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EAU90591.1 - 2.1e-13 49.6 2.5 2.1e-06 27.1 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EAU90591.1 - 4.4e-11 42.0 0.7 5.5e-09 35.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.18 EAU90591.1 - 2e-08 34.5 0.0 3.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.6 EAU90591.1 - 0.0061 16.7 4.0 0.48 10.6 0.3 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain SAM_PNT PF02198.11 EAU90591.1 - 0.0072 16.0 0.0 0.046 13.4 0.0 2.1 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain Glyco_hydro_43 PF04616.9 EAU90593.2 - 3.9e-46 157.4 1.3 4.6e-46 157.1 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DnaJ PF00226.26 EAU90594.2 - 3e-21 74.9 4.1 5.5e-21 74.0 2.8 1.5 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 EAU90595.2 - 3.5e-10 39.3 7.1 0.0024 17.6 0.7 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1192 PF06698.6 EAU90595.2 - 0.0095 15.7 0.1 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Nuc_N PF14448.1 EAU90595.2 - 0.07 12.6 0.1 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Nuclease N terminal RapA_C PF12137.3 EAU90595.2 - 0.09 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Coatomer_WDAD PF04053.9 EAU90595.2 - 0.14 10.9 0.1 0.53 9.0 0.0 1.9 2 1 1 3 3 3 0 Coatomer WD associated region IBR PF01485.16 EAU90596.1 - 1.2e-05 25.0 27.1 0.0017 18.1 2.6 3.7 2 2 0 3 3 3 2 IBR domain zf-RING_5 PF14634.1 EAU90596.1 - 0.0054 16.4 5.2 0.0054 16.4 3.6 3.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EAU90596.1 - 0.0059 16.4 6.3 0.0059 16.4 4.4 4.3 2 1 2 4 4 4 3 Ring finger domain GFA PF04828.9 EAU90596.1 - 0.042 13.8 0.1 0.042 13.8 0.1 4.3 2 1 1 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme zf-RING_UBOX PF13445.1 EAU90596.1 - 0.19 11.5 12.2 4.3 7.1 3.8 3.4 3 0 0 3 3 3 0 RING-type zinc-finger zf-TFIIB PF13453.1 EAU90596.1 - 3.2 7.0 13.9 0.39 9.9 0.5 3.8 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-C3HC4_4 PF15227.1 EAU90596.1 - 5.1 7.0 29.5 0.044 13.6 1.4 5.1 4 1 2 6 6 6 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EAU90597.1 - 9.3e-09 34.9 10.3 2.1e-08 33.8 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAU90597.1 - 2.9e-07 30.0 12.4 4e-07 29.5 7.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90597.1 - 1.8e-05 24.3 11.1 6.4e-05 22.5 7.7 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAU90597.1 - 3.4e-05 23.7 10.1 8e-05 22.5 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU90597.1 - 0.0091 15.8 7.4 0.033 14.0 5.1 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Di19 PF05605.7 EAU90597.1 - 0.041 14.0 1.1 0.041 14.0 0.8 2.5 2 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.1 EAU90597.1 - 0.05 13.3 7.0 0.11 12.2 4.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_IE-1 PF05290.6 EAU90597.1 - 0.056 13.1 2.5 0.082 12.6 1.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.1 EAU90597.1 - 0.1 12.3 3.8 0.2 11.4 2.4 1.7 2 1 0 2 2 2 0 Zinc-binding RING-finger V-set_CD47 PF08204.6 EAU90597.1 - 0.13 11.9 0.5 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain zf-rbx1 PF12678.2 EAU90597.1 - 0.34 11.0 9.0 0.75 9.9 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EAU90597.1 - 0.43 10.3 4.3 1.6 8.6 3.0 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein PHD PF00628.24 EAU90597.1 - 0.46 10.2 8.2 0.81 9.4 5.7 1.4 1 0 0 1 1 1 0 PHD-finger PQ-loop PF04193.9 EAU90598.2 - 1.5e-12 46.8 1.5 2.3e-12 46.2 1.1 1.3 1 0 0 1 1 1 1 PQ loop repeat L_HGMIC_fpl PF10242.4 EAU90598.2 - 0.013 15.4 0.5 0.025 14.5 0.4 1.4 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein NicO PF03824.11 EAU90598.2 - 0.042 13.1 0.7 0.11 11.7 0.2 1.8 1 1 1 2 2 2 0 High-affinity nickel-transport protein ER_lumen_recept PF00810.13 EAU90598.2 - 2 8.9 5.0 1 9.8 1.1 1.9 1 1 1 2 2 2 0 ER lumen protein retaining receptor Tmemb_14 PF03647.8 EAU90599.2 - 2.1e-16 60.0 5.4 2.6e-16 59.7 3.7 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C MtrC PF04211.8 EAU90599.2 - 0.49 9.3 3.6 0.5 9.3 2.5 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C SIR2 PF02146.12 EAU90600.2 - 1.6e-27 96.3 0.0 2.9e-27 95.5 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Kei1 PF08552.6 EAU90601.2 - 5.2e-14 52.3 2.6 5.2e-14 52.3 1.8 2.1 2 1 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 IF4E PF01652.13 EAU90602.1 - 4.2e-47 159.7 0.0 5.9e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SelR PF01641.13 EAU90603.1 - 7.2e-56 187.2 0.1 8.1e-56 187.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 EAU90603.1 - 0.0052 16.6 4.5 0.037 13.8 0.2 3.1 3 1 1 4 4 4 1 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.9 EAU90603.1 - 0.011 15.6 0.4 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_S27e PF01667.12 EAU90603.1 - 0.019 14.4 0.5 0.96 9.0 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 DZR PF12773.2 EAU90603.1 - 0.03 14.1 1.8 0.18 11.6 1.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon DUF678 PF05077.7 EAU90603.1 - 0.045 13.7 0.1 2.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) DNA_RNApol_7kD PF03604.8 EAU90603.1 - 0.1 12.1 3.2 3.3 7.2 0.2 2.8 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Yippee-Mis18 PF03226.9 EAU90603.1 - 0.1 12.6 0.7 0.58 10.2 0.5 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 EAU90603.1 - 0.12 11.5 3.1 7.7 5.8 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37e PF01907.14 EAU90603.1 - 0.27 11.0 4.9 1.8 8.4 0.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e DnaJ_CXXCXGXG PF00684.14 EAU90603.1 - 0.35 10.9 3.5 0.65 10.0 0.2 2.3 2 1 0 2 2 2 0 DnaJ central domain DUF2408 PF10303.4 EAU90605.2 - 4.6e-46 156.2 10.1 1.7e-27 96.1 0.5 5.2 4 1 1 5 5 5 5 Protein of unknown function (DUF2408) RPN7 PF10602.4 EAU90605.2 - 0.0086 15.4 0.2 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 V-SNARE PF05008.10 EAU90605.2 - 0.024 14.7 6.1 0.037 14.1 0.2 3.9 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Aida_N PF08910.5 EAU90605.2 - 0.096 12.9 0.2 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 Aida N-terminus Snapin_Pallidin PF14712.1 EAU90605.2 - 0.97 9.7 12.4 5.6 7.3 0.1 5.0 4 2 0 5 5 5 0 Snapin/Pallidin IncA PF04156.9 EAU90605.2 - 2.4 7.6 8.8 0.56 9.7 1.3 2.6 2 1 0 3 3 3 0 IncA protein Voltage_CLC PF00654.15 EAU90606.2 - 2.4e-13 49.8 20.5 5.4e-09 35.5 4.3 4.5 3 2 1 4 4 4 3 Voltage gated chloride channel CBS PF00571.23 EAU90606.2 - 2.1e-07 30.5 0.1 6.9e-07 28.9 0.0 1.9 2 0 0 2 2 2 1 CBS domain Med4 PF10018.4 EAU90607.2 - 1.4e-23 83.2 0.1 1.8e-23 82.9 0.1 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 FH2 PF02181.18 EAU90607.2 - 0.023 13.5 0.2 0.03 13.2 0.2 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain DSPc PF00782.15 EAU90608.1 - 2.9e-31 107.8 0.0 4.2e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAU90608.1 - 1.8e-06 27.4 0.2 2.7e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EAU90608.1 - 0.0027 16.6 0.1 0.0063 15.4 0.0 1.6 1 1 1 2 2 2 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 EAU90608.1 - 0.02 15.1 0.1 0.12 12.5 0.0 2.0 1 1 1 2 2 2 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EAU90608.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPn PF14671.1 EAU90608.1 - 0.061 13.3 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half NADH-u_ox-rdase PF10785.4 EAU90611.1 - 5.1e-35 119.5 1.4 7e-35 119.1 1.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EAU90611.1 - 4.2e-17 61.6 0.0 6.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF2530 PF10745.4 EAU90611.1 - 0.04 13.8 0.1 0.06 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF3943 PF13084.1 EAU90611.1 - 0.28 10.7 1.2 16 5.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) zf-RanBP PF00641.13 EAU90612.1 - 8.4e-08 31.1 36.3 7e-06 25.0 3.3 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Pkinase PF00069.20 EAU90613.1 - 2.6e-72 243.1 0.0 3e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU90613.1 - 4.1e-31 107.9 0.0 1.8e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EAU90613.1 - 0.0076 16.0 0.1 0.018 14.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU90613.1 - 0.099 11.5 0.0 0.58 9.0 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DnaJ PF00226.26 EAU90614.1 - 4.3e-20 71.2 2.3 6.6e-20 70.6 1.0 1.8 2 0 0 2 2 2 1 DnaJ domain Couple_hipA PF13657.1 EAU90614.1 - 0.13 12.6 0.2 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 HipA N-terminal domain Integrin_b_cyt PF08725.6 EAU90614.1 - 0.18 11.2 0.7 0.58 9.5 0.5 1.8 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain CCER1 PF15482.1 EAU90614.1 - 1.5 8.4 5.2 2.7 7.5 3.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 OHCU_decarbox PF09349.5 EAU90615.1 - 4.4e-31 108.3 0.0 5.4e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DUF2559 PF10832.3 EAU90615.1 - 0.087 12.6 0.0 7.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) GFO_IDH_MocA PF01408.17 EAU90616.1 - 2.2e-21 76.5 0.1 3.2e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF4010 PF13194.1 EAU90616.1 - 0.2 10.9 1.6 0.34 10.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) zf-RING_2 PF13639.1 EAU90619.2 - 2.4e-07 30.4 6.4 2.4e-07 30.4 4.4 3.8 2 1 1 3 3 3 1 Ring finger domain IBR PF01485.16 EAU90619.2 - 5.5e-07 29.3 26.6 1.2e-05 25.1 6.5 3.7 2 1 1 3 3 3 3 IBR domain zf-RING_5 PF14634.1 EAU90619.2 - 1.6e-06 27.7 4.9 1.6e-06 27.7 3.4 4.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU90619.2 - 2.5e-06 27.0 5.7 2.5e-06 27.0 4.0 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU90619.2 - 0.0001 22.2 6.8 0.0001 22.2 4.7 4.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU90619.2 - 0.00096 18.8 2.9 0.027 14.1 0.6 3.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAU90619.2 - 0.012 15.4 3.3 0.012 15.4 2.3 4.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EAU90620.2 - 0.00013 21.6 7.5 0.00026 20.6 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EAU90620.2 - 0.00092 18.8 6.7 0.0026 17.3 4.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU90620.2 - 0.0051 16.8 7.9 0.012 15.6 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU90620.2 - 0.0077 16.0 9.4 0.021 14.6 6.5 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU90620.2 - 3.9 7.4 9.0 0.16 11.8 2.1 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CHAT PF12770.2 EAU90623.1 - 2.1e-26 92.7 0.0 2.4e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 CHAT domain F-box-like PF12937.2 EAU90624.2 - 6.4e-07 29.0 1.8 0.014 15.1 0.1 3.0 2 0 0 2 2 2 2 F-box-like DUF960 PF06124.6 EAU90624.2 - 0.031 14.5 0.1 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Staphylococcal protein of unknown function (DUF960) DUF3420 PF11900.3 EAU90624.2 - 0.039 14.0 0.0 6 7.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3420) IL4Ra_N PF09238.5 EAU90624.2 - 0.082 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal F-box PF00646.28 EAU90624.2 - 0.17 11.5 2.0 1.5 8.5 0.2 2.9 2 0 0 2 2 2 0 F-box domain zf-MYND PF01753.13 EAU90625.1 - 6.2e-12 45.1 10.7 9.5e-12 44.5 7.4 1.3 1 0 0 1 1 1 1 MYND finger CBS PF00571.23 EAU90626.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 CBS domain Lipase_3 PF01764.20 EAU90628.1 - 7.2e-22 77.5 0.0 1.1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EAU90628.1 - 0.0017 18.1 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU90628.1 - 0.0073 16.2 0.2 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAU90628.1 - 0.014 14.9 0.2 0.018 14.6 0.1 1.1 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 EAU90628.1 - 0.029 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EAU90628.1 - 0.035 13.6 0.1 0.053 13.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EAU90628.1 - 0.11 11.8 0.6 0.18 11.1 0.4 1.2 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.3 EAU90628.1 - 0.14 11.4 0.3 0.25 10.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PAF-AH_p_II PF03403.8 EAU90628.1 - 0.22 9.7 0.2 0.3 9.3 0.1 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Syndecan PF01034.15 EAU90629.1 - 0.21 11.2 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain F-box-like PF12937.2 EAU90630.2 - 4.8e-10 38.9 2.7 1.5e-09 37.4 1.9 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU90632.2 - 2e-09 37.0 2.8 2.5e-09 36.6 0.7 2.1 2 0 0 2 2 2 1 F-box-like 4HBT_2 PF13279.1 EAU90634.2 - 3.3e-14 53.3 0.0 5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EAU90634.2 - 3.8e-07 30.1 0.0 7.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EAU90634.2 - 0.013 14.5 0.0 0.025 13.5 0.0 1.5 2 0 0 2 2 2 0 Acyl-ACP thioesterase AMP-binding PF00501.23 EAU90635.2 - 1.3e-43 148.9 0.0 2e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EAU90635.2 - 1.5e-10 41.1 0.2 3.6e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EAU90635.2 - 2.7e-10 41.0 0.0 0.00095 20.0 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Hexapep PF00132.19 EAU90635.2 - 2.8e-08 32.9 10.5 0.00026 20.3 0.0 6.3 7 0 0 7 7 7 3 Bacterial transferase hexapeptide (six repeats) zf-C3HC4_3 PF13920.1 EAU90635.2 - 0.0033 17.0 3.6 0.007 16.0 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU90635.2 - 0.0042 16.7 2.9 0.01 15.4 2.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90635.2 - 0.012 15.3 1.0 0.029 14.0 0.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EAU90635.2 - 0.013 15.5 2.6 0.03 14.3 1.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU90635.2 - 0.74 9.6 3.2 1.9 8.4 2.2 1.7 1 0 0 1 1 1 0 Ring finger domain CAP_GLY PF01302.20 EAU90638.1 - 2.8e-28 97.4 2.5 4.5e-28 96.7 1.7 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EAU90638.1 - 1.3e-26 92.6 0.0 2.2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EAU90638.1 - 0.00061 19.1 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family AAA PF00004.24 EAU90639.1 - 1.3e-96 319.7 0.0 4.9e-47 159.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EAU90639.1 - 9.9e-21 73.4 0.8 9.9e-20 70.2 0.2 2.6 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EAU90639.1 - 1.3e-13 51.2 0.0 1.3e-07 31.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EAU90639.1 - 1.6e-13 50.2 0.0 1.9e-05 23.8 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EAU90639.1 - 6.4e-13 48.7 0.0 1.2e-06 28.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EAU90639.1 - 8.1e-13 49.2 0.0 0.00014 22.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EAU90639.1 - 3.8e-12 46.1 0.3 7.6e-06 25.7 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU90639.1 - 2.7e-11 43.7 0.1 0.0018 18.4 0.0 4.1 2 2 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EAU90639.1 - 7.8e-11 41.4 0.0 1.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 EAU90639.1 - 1e-09 38.6 0.0 0.0025 17.8 0.0 3.4 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EAU90639.1 - 2.5e-09 36.3 0.1 0.0012 17.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EAU90639.1 - 4e-08 32.8 0.0 0.0044 16.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EAU90639.1 - 9.4e-08 32.0 0.0 0.0075 16.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EAU90639.1 - 1e-07 31.2 0.0 0.0093 15.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EAU90639.1 - 1.4e-07 31.1 3.2 0.022 14.1 0.0 3.8 2 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 EAU90639.1 - 3.3e-07 29.9 1.8 0.0093 15.6 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Mg_chelatase PF01078.16 EAU90639.1 - 3.9e-07 29.4 0.4 0.024 13.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EAU90639.1 - 1.2e-06 28.5 0.0 0.019 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.5 EAU90639.1 - 1.3e-06 28.1 0.2 1e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 EAU90639.1 - 1.7e-06 28.3 0.0 0.032 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EAU90639.1 - 3.3e-06 26.3 0.8 0.7 8.9 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_28 PF13521.1 EAU90639.1 - 5.4e-06 26.4 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EAU90639.1 - 9.6e-06 24.6 0.1 0.009 14.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 EAU90639.1 - 9.8e-06 25.5 0.0 0.0052 16.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EAU90639.1 - 2.3e-05 23.9 0.0 0.45 9.9 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EAU90639.1 - 3.1e-05 24.2 0.0 0.19 12.0 0.0 3.6 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 EAU90639.1 - 3.1e-05 23.6 0.1 0.099 12.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.8 EAU90639.1 - 4.2e-05 22.5 0.0 0.014 14.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EAU90639.1 - 5.6e-05 22.4 0.2 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EAU90639.1 - 7.9e-05 22.7 0.0 0.33 11.0 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 EAU90639.1 - 0.00012 21.8 0.0 0.52 9.9 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Arch_ATPase PF01637.13 EAU90639.1 - 0.00017 21.3 0.1 3 7.4 0.1 3.3 2 1 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 EAU90639.1 - 0.00021 20.9 0.0 0.56 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EAU90639.1 - 0.00034 20.2 0.0 0.74 9.3 0.0 2.5 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EAU90639.1 - 0.00062 19.4 0.1 0.68 9.5 0.0 3.4 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EAU90639.1 - 0.00087 18.3 0.0 0.4 9.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EAU90639.1 - 0.0015 18.1 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EAU90639.1 - 0.0018 17.2 0.0 0.12 11.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EAU90639.1 - 0.0019 17.7 0.0 0.23 10.9 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EAU90639.1 - 0.0051 15.7 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EAU90639.1 - 0.0058 16.3 0.3 1.9 8.1 0.0 3.4 3 0 0 3 3 3 1 NTPase KAP_NTPase PF07693.9 EAU90639.1 - 0.025 13.5 0.0 0.6 9.0 0.0 2.4 2 1 0 2 2 2 0 KAP family P-loop domain IPT PF01745.11 EAU90639.1 - 0.031 13.4 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase SKI PF01202.17 EAU90639.1 - 0.037 13.8 0.0 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EAU90639.1 - 0.044 13.4 0.1 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 EAU90639.1 - 0.046 13.2 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UFD1 PF03152.9 EAU90639.1 - 0.054 12.6 0.0 0.18 10.9 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Molydop_binding PF01568.16 EAU90639.1 - 0.091 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain PIF1 PF05970.9 EAU90639.1 - 0.092 11.6 0.0 7 5.4 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase KTI12 PF08433.5 EAU90639.1 - 0.096 11.8 0.0 12 5.0 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 EAU90639.1 - 0.12 11.7 1.8 7.1 5.9 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain Zot PF05707.7 EAU90639.1 - 0.21 11.0 0.1 28 4.1 0.1 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DAGAT PF03982.8 EAU90640.2 - 2.8e-102 341.3 0.0 3.7e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF3464 PF11947.3 EAU90640.2 - 0.19 11.2 1.2 0.39 10.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) F-box-like PF12937.2 EAU90641.1 - 0.0018 17.9 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like UPF0075 PF03702.9 EAU90641.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) F-box-like PF12937.2 EAU90642.1 - 0.00041 20.0 0.2 0.00041 20.0 0.2 2.4 3 0 0 3 3 3 1 F-box-like TRAPPC9-Trs120 PF08626.6 EAU90642.1 - 0.25 8.6 0.2 1.1 6.4 0.1 1.8 2 0 0 2 2 2 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit LRR_4 PF12799.2 EAU90642.1 - 5.3 6.7 7.5 12 5.6 0.6 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Lipase_3 PF01764.20 EAU90643.1 - 2e-24 85.8 0.0 3e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EAU90643.1 - 0.00047 20.0 1.7 0.0007 19.5 0.8 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU90643.1 - 0.00056 19.6 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAU90643.1 - 0.00099 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EAU90643.1 - 0.0015 18.1 0.2 0.0065 16.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 EAU90643.1 - 0.0024 17.2 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.3 EAU90643.1 - 0.0084 15.4 0.2 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_8 PF06259.7 EAU90643.1 - 0.034 13.6 0.1 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.15 EAU90643.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Pkinase PF00069.20 EAU90644.2 - 7.1e-06 25.3 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EAU90644.2 - 0.036 13.7 0.2 0.13 11.9 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family STT3 PF02516.9 EAU90645.1 - 7.1e-136 453.9 37.2 4.6e-133 444.7 25.8 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Med3 PF11593.3 EAU90645.1 - 0.094 11.9 3.8 0.13 11.4 2.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal p450 PF00067.17 EAU90649.2 - 3e-35 121.6 0.1 8.4e-22 77.3 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 Hirudin PF00713.12 EAU90649.2 - 0.045 13.8 0.1 0.12 12.5 0.1 1.7 1 0 0 1 1 1 0 Hirudin Ino80_Iec3 PF14612.1 EAU90652.2 - 0.0048 16.9 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling FAM212 PF15342.1 EAU90653.2 - 0.13 11.8 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 FAM212 family Podoplanin PF05808.6 EAU90654.2 - 0.017 14.6 1.0 0.031 13.8 0.7 1.5 1 1 0 1 1 1 0 Podoplanin Rick_17kDa_Anti PF05433.10 EAU90654.2 - 0.21 11.2 2.6 0.54 9.9 1.8 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain Lipase_3 PF01764.20 EAU90656.1 - 2.6e-21 75.7 0.0 3.5e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 EAU90656.1 - 8.1e-05 22.2 0.1 0.00022 20.8 0.1 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU90656.1 - 0.00016 21.6 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU90656.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EAU90656.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EAU90656.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Mt_ATP-synt_B PF05405.9 EAU90657.1 - 6.1e-44 149.3 10.5 7.3e-44 149.0 7.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2526 PF10735.4 EAU90657.1 - 0.016 15.1 0.7 0.044 13.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) DUF1539 PF07560.6 EAU90657.1 - 0.078 12.8 1.7 0.095 12.5 0.6 1.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) S-AdoMet_synt_N PF00438.15 EAU90657.1 - 0.14 12.3 2.6 0.46 10.7 0.6 2.6 1 1 2 3 3 3 0 S-adenosylmethionine synthetase, N-terminal domain RCC1 PF00415.13 EAU90663.2 - 1.2e-39 134.3 11.9 1.1e-10 41.5 0.0 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAU90663.2 - 9.6e-22 76.0 27.2 5.2e-07 29.1 0.3 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 EAU90663.2 - 5.7e-09 35.5 7.0 5.7e-09 35.5 4.8 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EAU90663.2 - 0.0023 17.5 3.0 0.008 15.8 2.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 Reg_prop PF07494.6 EAU90663.2 - 0.081 12.9 0.3 19 5.7 0.0 3.2 2 0 0 2 2 2 0 Two component regulator propeller PBP1_TM PF14812.1 EAU90663.2 - 0.71 10.2 9.2 1.4 9.2 6.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD_2 PF13831.1 EAU90663.2 - 1.1 8.6 8.2 0.45 9.8 0.3 3.1 3 0 0 3 3 3 0 PHD-finger MULE PF10551.4 EAU90664.2 - 2.8e-07 30.6 0.2 8.3e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain LEAP-2 PF07359.6 EAU90664.2 - 0.039 13.6 0.3 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) F-box PF00646.28 EAU90666.1 - 0.00024 20.6 0.6 0.41 10.3 0.0 2.9 2 1 0 2 2 2 2 F-box domain F-box-like PF12937.2 EAU90666.1 - 0.0011 18.6 0.2 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like Cu-oxidase PF00394.17 EAU90667.2 - 4.7e-44 150.1 0.1 3.1e-41 140.9 0.0 2.9 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU90667.2 - 1.8e-40 137.6 6.7 1.6e-37 128.0 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU90667.2 - 4.1e-35 120.0 0.2 5.6e-33 113.1 0.1 3.2 3 0 0 3 3 3 1 Multicopper oxidase tRNA_NucTransf2 PF09249.6 EAU90667.2 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain F-box-like PF12937.2 EAU90669.2 - 8.7e-08 31.7 2.3 9e-08 31.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EAU90669.2 - 1.8 8.2 13.1 14 5.4 0.1 5.0 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Cu-oxidase PF00394.17 EAU90671.2 - 5e-42 143.4 0.1 2.8e-39 134.5 0.0 2.9 2 1 1 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU90671.2 - 3.9e-32 110.6 5.0 3.5e-30 104.3 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU90671.2 - 4.1e-31 107.1 0.6 2e-30 104.9 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase GMC_oxred_N PF00732.14 EAU90672.2 - 5e-64 216.3 0.0 7.5e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU90672.2 - 3.4e-24 85.7 0.0 5.6e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU90672.2 - 0.0007 19.5 0.2 0.0084 16.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAU90672.2 - 0.00093 18.2 0.2 0.0013 17.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EAU90672.2 - 0.0026 16.6 0.5 0.21 10.3 0.2 2.1 2 0 0 2 2 2 2 FAD binding domain WD40 PF00400.27 EAU90674.2 - 9.9e-49 161.5 21.8 7.4e-10 38.3 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EAU90674.2 - 0.00015 20.0 3.4 0.21 9.6 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 F-box-like PF12937.2 EAU90674.2 - 0.0066 16.1 0.1 0.021 14.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like Nucleoporin_N PF08801.6 EAU90674.2 - 0.013 14.2 0.0 0.049 12.3 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like BBS2_Mid PF14783.1 EAU90674.2 - 0.022 14.5 0.0 0.26 11.0 0.0 2.7 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EAU90674.2 - 0.34 11.2 12.6 27 5.2 0.1 5.5 5 0 0 5 5 5 0 PQQ-like domain Methyltransf_15 PF09445.5 EAU90675.1 - 1.3e-37 128.8 0.0 5.9e-37 126.7 0.0 1.8 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EAU90675.1 - 8.4e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU90675.1 - 1.2e-08 35.4 0.0 2.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU90675.1 - 2.6e-05 23.8 0.0 5.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EAU90675.1 - 3e-05 23.6 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EAU90675.1 - 4e-05 23.2 0.0 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.1 EAU90675.1 - 5.6e-05 23.4 0.0 0.00021 21.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EAU90675.1 - 0.0018 17.7 0.0 0.012 14.9 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 EAU90675.1 - 0.0055 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EAU90675.1 - 0.0073 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.8 EAU90675.1 - 0.019 14.1 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.21 EAU90675.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GMC_oxred_N PF00732.14 EAU90676.2 - 1.4e-40 139.2 2.6 1.2e-27 96.8 0.1 2.4 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU90676.2 - 1.4e-24 87.0 0.0 2.9e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EAU90676.2 - 0.0093 15.9 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EAU90676.2 - 0.036 12.9 0.1 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Cu-oxidase PF00394.17 EAU90677.1 - 1.6e-47 161.3 0.0 9.3e-44 149.1 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU90677.1 - 5.9e-35 119.5 0.6 1.8e-33 114.7 0.0 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU90677.1 - 6e-35 119.7 5.5 7.5e-33 112.9 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase RRM_6 PF14259.1 EAU90678.2 - 6.4e-05 22.8 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU90678.2 - 0.0055 16.3 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EAU90679.2 - 5.1e-08 32.5 0.0 1.9e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EAU90679.2 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAD_binding_3 PF01494.14 EAU90680.2 - 1.9e-23 83.0 0.0 1.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EAU90680.2 - 0.00023 21.1 0.3 0.00063 19.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EAU90680.2 - 0.006 15.2 0.2 0.017 13.7 0.1 1.8 1 1 1 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EAU90680.2 - 0.021 13.9 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EAU90680.2 - 0.032 13.1 0.4 0.081 11.8 0.3 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 EAU90680.2 - 0.066 12.0 0.0 0.82 8.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Peptidase_M28 PF04389.12 EAU90683.2 - 2.7e-30 105.4 0.1 6.3e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 DUF4048 PF13257.1 EAU90683.2 - 1.2 8.6 6.2 0.15 11.6 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) DUF2664 PF10867.3 EAU90684.2 - 0.017 15.7 6.3 0.044 14.4 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) Aminotran_5 PF00266.14 EAU90685.1 - 2.8e-46 157.9 0.0 3.5e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EAU90685.1 - 0.0036 16.3 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II IBR PF01485.16 EAU90686.2 - 4.8e-15 55.1 34.5 3.6e-08 33.1 6.5 3.7 3 0 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EAU90686.2 - 5.4e-07 29.1 2.8 5.4e-07 29.1 1.9 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU90686.2 - 1e-06 28.6 4.7 1e-06 28.6 3.2 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU90686.2 - 3.4e-05 23.4 2.5 3.4e-05 23.4 1.7 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EAU90686.2 - 4.2e-05 23.2 5.3 4.2e-05 23.2 3.7 3.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU90686.2 - 6.4e-05 22.7 5.7 6.4e-05 22.7 4.0 3.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING RRM_1 PF00076.17 EAU90686.2 - 0.00052 19.6 0.1 3 7.5 0.0 4.2 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EAU90686.2 - 0.00053 19.6 1.7 0.0013 18.4 1.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_6 PF14259.1 EAU90686.2 - 0.0035 17.2 0.0 0.25 11.3 0.0 3.4 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 EAU90687.2 - 5.6e-53 177.2 2.8 3.6e-13 49.6 0.0 5.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90687.2 - 2e-33 112.5 1.4 8e-06 25.4 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EAU90687.2 - 2.1e-30 104.5 1.1 1.6e-07 31.6 0.0 6.6 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90687.2 - 6.9e-30 102.4 1.8 1.4e-06 28.3 0.0 6.2 5 1 1 6 6 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90687.2 - 8.4e-28 93.6 0.1 0.0014 18.7 0.0 8.3 7 0 0 7 7 7 5 Ankyrin repeat NACHT PF05729.7 EAU90687.2 - 4.3e-05 23.2 0.1 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EAU90687.2 - 0.00013 22.1 0.0 0.00043 20.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAU90687.2 - 0.00014 20.8 0.1 0.00027 19.8 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EAU90687.2 - 0.0072 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EAU90687.2 - 0.011 15.9 0.1 0.033 14.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAU90687.2 - 0.05 13.5 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EAU90687.2 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NapD PF03927.8 EAU90687.2 - 0.14 12.0 0.0 0.57 10.0 0.0 2.1 1 0 0 1 1 1 0 NapD protein TPR_11 PF13414.1 EAU90688.2 - 1.1e-44 149.9 5.5 1.3e-19 69.6 0.5 5.5 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EAU90688.2 - 5.8e-28 95.3 1.3 7e-06 25.4 0.0 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90688.2 - 2.7e-26 89.3 6.5 0.00082 19.1 0.0 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat DnaJ PF00226.26 EAU90688.2 - 2.3e-23 81.6 0.4 6e-23 80.3 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_9 PF13371.1 EAU90688.2 - 6.1e-22 77.2 3.7 1.5e-06 27.9 0.1 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAU90688.2 - 1.7e-19 69.9 12.3 2.2e-07 31.3 0.0 6.3 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EAU90688.2 - 3.3e-14 52.9 11.9 0.00035 20.8 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAU90688.2 - 3.5e-13 48.9 14.9 0.011 16.3 0.0 7.7 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EAU90688.2 - 3.2e-12 46.2 5.8 0.00096 19.0 0.0 6.4 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAU90688.2 - 2e-11 42.7 0.8 0.65 9.9 0.1 6.3 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EAU90688.2 - 1.4e-09 37.4 6.0 0.026 14.6 0.1 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 EAU90688.2 - 1.3e-07 31.5 0.5 0.25 11.8 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU90688.2 - 2.6e-05 24.2 0.1 0.0072 16.4 0.0 3.6 3 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EAU90688.2 - 4.7e-05 23.1 3.9 0.087 12.7 0.0 4.6 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EAU90688.2 - 0.0018 17.9 1.4 17 5.5 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 EAU90688.2 - 0.0062 16.4 5.0 2.2 8.2 0.1 4.4 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EAU90688.2 - 0.031 14.2 2.4 20 5.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF342 PF03961.8 EAU90688.2 - 0.093 11.1 3.4 0.054 11.9 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4398 PF14346.1 EAU90688.2 - 0.33 11.0 11.5 1.1 9.3 1.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) FadA PF09403.5 EAU90688.2 - 4.2 7.3 7.9 4.6 7.2 0.0 3.1 4 0 0 4 4 3 0 Adhesion protein FadA IncA PF04156.9 EAU90689.2 - 0.036 13.6 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 IncA protein DUF1510 PF07423.6 EAU90689.2 - 0.32 10.3 2.5 0.37 10.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF2749 PF10907.3 EAU90689.2 - 2.5 8.0 6.8 0.29 11.0 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) F-box-like PF12937.2 EAU90694.2 - 0.017 14.8 0.2 0.054 13.2 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EAU90694.2 - 0.16 11.6 1.4 0.76 9.5 0.9 2.2 1 1 0 1 1 1 0 F-box domain Ank PF00023.25 EAU90698.2 - 5.6e-11 41.6 1.0 0.0033 17.1 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EAU90698.2 - 4.3e-09 36.6 0.0 4.2e-08 33.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90698.2 - 5.8e-09 35.9 0.1 2.7e-06 27.4 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU90698.2 - 1.8e-08 34.5 0.0 7.6e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.7 EAU90698.2 - 1.9e-06 27.6 0.0 1.5e-05 24.7 0.0 2.4 2 1 0 3 3 3 1 NACHT domain Ank_3 PF13606.1 EAU90698.2 - 4.9e-05 23.1 1.7 0.029 14.5 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat NB-ARC PF00931.17 EAU90698.2 - 0.0074 15.1 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EAU90698.2 - 0.015 15.4 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EAU90698.2 - 0.088 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EAU90698.2 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IBR PF01485.16 EAU90699.2 - 1.7e-12 47.0 21.3 1.6e-09 37.5 4.3 3.6 3 0 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EAU90699.2 - 0.0023 17.8 5.3 0.0023 17.8 3.7 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU90699.2 - 0.0082 15.7 5.1 0.0082 15.7 3.5 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EAU90699.2 - 0.019 14.6 9.0 0.19 11.4 1.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EAU90699.2 - 0.031 13.8 0.1 12 5.6 0.0 2.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.21 EAU90699.2 - 0.045 13.9 0.3 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 Heavy-metal-associated domain Macoilin PF09726.4 EAU90699.2 - 0.11 10.7 16.2 0.18 10.0 11.2 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 EAU90699.2 - 0.56 9.1 15.4 1.4 7.8 10.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ycf1 PF05758.7 EAU90699.2 - 0.75 7.4 6.3 1.1 6.9 4.3 1.2 1 0 0 1 1 1 0 Ycf1 AAA_12 PF13087.1 EAU90702.2 - 5.4e-57 192.4 0.0 9.3e-57 191.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EAU90702.2 - 2.2e-24 86.3 0.4 3.8e-24 85.5 0.3 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU90702.2 - 3.6e-12 45.8 0.3 1.5e-11 43.8 0.3 2.0 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EAU90702.2 - 1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EAU90702.2 - 1.2e-05 24.9 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EAU90702.2 - 0.0026 17.2 0.1 2.6 7.5 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase CENP-Q PF13094.1 EAU90702.2 - 0.069 13.1 2.8 0.18 11.8 1.9 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ank_2 PF12796.2 EAU90705.2 - 7e-55 183.3 12.6 6.4e-13 48.8 0.0 5.9 2 2 5 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90705.2 - 2.3e-39 131.2 16.0 2.2e-07 30.3 0.0 10.3 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EAU90705.2 - 1.1e-29 102.1 9.2 4.7e-06 26.9 0.0 8.2 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90705.2 - 1.1e-22 79.5 11.2 6.7e-07 29.3 0.0 6.5 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90705.2 - 4.3e-21 72.8 1.4 0.036 14.2 0.1 8.8 9 0 0 9 9 9 5 Ankyrin repeat NACHT PF05729.7 EAU90705.2 - 0.00026 20.6 0.1 0.00082 19.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU90705.2 - 0.008 16.1 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU90705.2 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EAU90705.2 - 0.018 15.3 0.0 0.053 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EAU90705.2 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3820 PF12843.2 EAU90706.2 - 0.0031 17.0 0.2 0.0056 16.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3820) SET PF00856.23 EAU90707.1 - 6.6e-12 46.0 0.0 2.6e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 SET domain DUF2714 PF10896.3 EAU90707.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2714) Ank_2 PF12796.2 EAU90708.2 - 5e-59 196.6 9.8 8.5e-15 54.8 0.1 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAU90708.2 - 1.9e-48 159.9 7.6 3.6e-08 32.7 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EAU90708.2 - 2.3e-37 126.7 3.5 7.6e-08 32.6 0.0 8.3 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU90708.2 - 2.4e-27 94.3 6.7 1.2e-06 28.5 0.2 5.7 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU90708.2 - 1.2e-24 83.8 0.7 0.0015 18.5 0.0 8.5 8 0 0 8 8 8 5 Ankyrin repeat NapD PF03927.8 EAU90708.2 - 0.091 12.5 0.0 16 5.3 0.0 3.8 2 1 3 5 5 5 0 NapD protein SQS_PSY PF00494.14 EAU90709.2 - 2.6e-43 148.2 0.0 3.4e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Sensor PF13796.1 EAU90713.2 - 0.16 11.5 1.4 0.2 11.2 1.0 1.2 1 0 0 1 1 1 0 Putative sensor CAP_N PF01213.14 EAU90713.2 - 0.23 10.6 8.1 0.25 10.6 5.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM171 PF15471.1 EAU90713.2 - 7.4 5.2 6.3 9.1 4.9 4.4 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 SET PF00856.23 EAU90717.1 - 8e-09 36.0 0.0 3.3e-07 30.7 0.0 2.6 1 1 0 1 1 1 1 SET domain SE PF08491.5 EAU90718.1 - 9.1e-95 316.6 0.0 1.2e-94 316.1 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EAU90718.1 - 1.3e-13 50.6 0.3 1.7e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU90718.1 - 1.6e-09 37.2 0.8 3.7e-05 22.9 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 EAU90718.1 - 9e-07 28.0 0.5 0.011 14.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EAU90718.1 - 2.9e-05 23.1 0.2 0.007 15.3 0.1 3.0 2 1 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EAU90718.1 - 8e-05 22.6 0.6 0.00024 21.0 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EAU90718.1 - 0.00098 18.0 0.8 0.28 10.0 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.9 EAU90718.1 - 0.0024 16.5 0.4 1.8 7.0 0.0 2.6 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EAU90718.1 - 0.0046 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EAU90718.1 - 0.007 16.1 0.4 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 EAU90718.1 - 0.012 14.8 0.2 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.12 EAU90718.1 - 0.027 13.5 0.1 0.06 12.4 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EAU90718.1 - 0.034 14.5 0.0 3.2 8.2 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1467 PF07330.7 EAU90718.1 - 0.038 13.7 0.1 0.094 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) dCMP_cyt_deam_1 PF00383.17 EAU90719.2 - 1.3e-19 69.7 0.0 1.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EAU90719.2 - 2.7e-14 53.2 0.2 1.2e-11 44.7 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EAU90719.2 - 0.0017 17.7 2.3 0.035 13.5 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases ADH_N PF08240.7 EAU90719.2 - 0.055 13.2 0.1 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DnaJ PF00226.26 EAU90721.2 - 4.3e-10 39.1 0.0 8.4e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain F-box-like PF12937.2 EAU90722.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like Mg_chelatase_2 PF13335.1 EAU90722.1 - 0.094 13.1 0.0 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF3763 PF12592.3 EAU90722.1 - 0.11 12.0 0.2 1.9 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) Rootletin PF15035.1 EAU90725.2 - 0.017 15.1 0.9 0.088 12.7 0.1 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ArfGap PF01412.13 EAU90725.2 - 0.039 13.7 1.6 0.11 12.2 1.1 1.8 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf PepX_N PF09168.5 EAU90725.2 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Tet_JBP PF12851.2 EAU90730.2 - 1.3e-26 92.8 0.0 2.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EAU90730.2 - 0.075 13.5 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CHAT PF12770.2 EAU90732.2 - 6.5e-29 100.9 0.0 1.1e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU90732.2 - 7.6e-29 99.4 10.5 0.0017 18.2 0.0 14.4 3 2 11 15 15 15 9 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90732.2 - 1.8e-23 81.9 2.0 0.0082 15.7 0.0 12.7 3 3 10 14 14 14 5 TPR repeat TPR_10 PF13374.1 EAU90732.2 - 9.9e-17 60.2 18.8 0.21 11.5 0.0 13.5 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_17 PF13431.1 EAU90732.2 - 1.3e-07 31.2 1.7 14 6.1 0.0 8.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90732.2 - 5.5e-07 29.0 10.5 9.3 6.4 0.0 11.4 13 0 0 13 13 12 2 Tetratricopeptide repeat MIT PF04212.13 EAU90732.2 - 0.00025 20.8 0.1 22 4.9 0.0 6.3 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 EAU90732.2 - 0.0053 16.3 12.6 8.4 6.1 0.0 9.3 11 0 0 11 11 11 1 Tetratricopeptide repeat Flu_NS2 PF00601.14 EAU90732.2 - 0.023 14.8 0.3 62 3.8 0.0 4.9 3 1 1 4 4 3 0 Influenza non-structural protein (NS2) TrbM PF07424.6 EAU90732.2 - 0.063 13.2 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 TrbM L27_2 PF09045.5 EAU90732.2 - 0.093 12.2 1.3 0.58 9.7 0.2 3.1 2 0 0 2 2 2 0 L27_2 Mtf2_C PF14061.1 EAU90732.2 - 0.2 11.6 0.0 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Exonuc_VII_S PF02609.11 EAU90732.2 - 6.8 6.5 8.6 29 4.5 0.1 5.2 7 0 0 7 7 6 0 Exonuclease VII small subunit RCC1 PF00415.13 EAU90733.2 - 2.8e-24 85.0 0.7 5e-05 23.4 0.0 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EAU90733.2 - 2.7e-14 53.1 0.0 2e-05 24.5 0.0 3.4 2 1 1 3 3 3 2 BTB/POZ domain Ank_5 PF13857.1 EAU90733.2 - 1.4e-12 47.4 1.0 1.6e-06 28.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU90733.2 - 7.9e-10 38.9 0.3 3.2e-09 37.0 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EAU90733.2 - 2.6e-08 33.2 5.5 1.3e-07 30.9 0.0 4.7 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.2 EAU90733.2 - 6.9e-08 32.7 0.1 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EAU90733.2 - 1.4e-07 31.0 0.9 0.0046 17.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EAU90733.2 - 1.8e-05 24.3 0.4 0.17 11.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat CHAT PF12770.2 EAU90735.2 - 2.4e-27 95.8 0.0 5.7e-27 94.5 0.0 1.6 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EAU90735.2 - 2.6e-27 94.5 9.7 0.014 15.2 0.0 12.2 4 2 8 12 12 12 9 Tetratricopeptide repeat TPR_10 PF13374.1 EAU90735.2 - 2.9e-23 81.0 15.8 0.09 12.7 0.0 11.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90735.2 - 3.5e-13 48.9 11.8 2.1 8.0 0.2 9.8 4 1 7 11 11 11 6 TPR repeat TPR_17 PF13431.1 EAU90735.2 - 1.3e-09 37.5 1.0 0.98 9.7 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90735.2 - 0.00058 19.3 0.6 1e+02 2.7 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90735.2 - 0.0011 18.7 1.8 74 3.6 0.0 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Flu_NS2 PF00601.14 EAU90735.2 - 0.14 12.3 4.0 31 4.8 0.0 6.0 8 0 0 8 8 8 0 Influenza non-structural protein (NS2) DUF4398 PF14346.1 EAU90735.2 - 5.8 7.0 6.5 0.76 9.8 0.3 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4398) Dynamin_M PF01031.15 EAU90739.2 - 8.1e-111 369.5 0.0 1.3e-110 368.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EAU90739.2 - 5.5e-54 182.4 0.0 9.5e-54 181.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EAU90739.2 - 5.9e-31 106.2 3.7 9.8e-30 102.3 1.2 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAU90739.2 - 0.0022 17.9 0.1 0.011 15.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EAU90739.2 - 0.0043 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.11 EAU90739.2 - 0.013 14.6 0.1 4.3 6.3 0.0 2.4 2 0 0 2 2 2 0 AIG1 family Baculo_p74 PF04583.7 EAU90739.2 - 0.025 13.7 0.1 5.8 6.0 0.1 2.2 2 0 0 2 2 2 0 Baculoviridae p74 conserved region Condensin2nSMC PF12422.3 EAU90739.2 - 0.03 14.0 0.2 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit ABC_tran PF00005.22 EAU90739.2 - 0.048 13.9 0.0 8.5 6.6 0.0 3.2 3 0 0 3 3 3 0 ABC transporter Miro PF08477.8 EAU90739.2 - 0.07 13.6 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein TPR_12 PF13424.1 EAU90740.1 - 5.5e-23 80.6 3.0 0.018 14.9 0.0 11.1 4 1 9 13 13 13 8 Tetratricopeptide repeat CHAT PF12770.2 EAU90740.1 - 1.5e-22 80.1 0.0 2.5e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.1 EAU90740.1 - 1.6e-16 59.6 20.5 0.014 15.3 0.0 11.7 10 2 1 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90740.1 - 8.7e-12 44.5 4.6 0.079 12.6 0.0 8.7 4 2 6 10 10 10 3 TPR repeat TPR_17 PF13431.1 EAU90740.1 - 5.8e-08 32.3 0.3 8.6 6.8 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU90740.1 - 5.8e-05 23.6 14.9 0.0085 16.7 0.3 6.3 7 1 1 8 8 8 2 Tetratricopeptide repeat DnaB_bind PF10410.4 EAU90740.1 - 0.059 13.3 4.1 16 5.5 0.0 5.5 7 0 0 7 7 7 0 DnaB-helicase binding domain of primase BCS1_N PF08740.6 EAU90741.2 - 1.6e-29 102.8 0.4 1.6e-29 102.8 0.3 2.9 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 EAU90741.2 - 3.4e-15 56.4 0.0 1.5e-07 31.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAU90741.2 - 0.00096 19.0 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU90741.2 - 0.003 17.5 0.2 0.003 17.5 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 EAU90741.2 - 0.0072 15.4 0.0 0.39 9.7 0.0 2.6 3 0 0 3 3 3 1 KaiC AAA_17 PF13207.1 EAU90741.2 - 0.0083 16.9 0.0 0.0083 16.9 0.0 2.9 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EAU90741.2 - 0.0084 15.6 0.0 0.0084 15.6 0.0 2.0 2 1 0 2 2 1 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EAU90741.2 - 0.012 15.2 13.8 0.0044 16.6 7.6 1.8 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.7 EAU90741.2 - 0.053 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EAU90741.2 - 0.073 12.7 0.2 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.6 EAU90741.2 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNase_H2_suC PF08615.6 EAU90742.1 - 5.4e-23 81.3 0.1 8.5e-23 80.7 0.1 1.3 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MelC1 PF06236.6 EAU90742.1 - 0.22 11.5 1.8 0.29 11.1 0.3 1.9 1 1 1 2 2 2 0 Tyrosinase co-factor MelC1 Fib_succ_major PF09603.5 EAU90744.2 - 0.17 12.3 0.9 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 Fibrobacter succinogenes major domain (Fib_succ_major) CAF-1_p150 PF11600.3 EAU90744.2 - 0.44 9.8 11.9 0.84 8.9 8.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-Nse PF11789.3 EAU90745.1 - 0.12 11.9 0.1 0.67 9.5 0.0 2.3 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit GPI-anchored PF10342.4 EAU90746.1 - 9.4e-12 45.2 1.1 1.5e-11 44.5 0.7 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Nucleoplasmin PF03066.10 EAU90746.1 - 0.078 12.4 0.6 0.13 11.8 0.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EAU90746.1 - 0.34 11.2 4.0 0.57 10.5 2.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3246 PF11596.3 EAU90746.1 - 0.53 9.5 10.7 0.073 12.3 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Sigma70_ner PF04546.8 EAU90746.1 - 1.4 8.4 3.8 2.1 7.9 2.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BAF1_ABF1 PF04684.8 EAU90746.1 - 3 6.5 6.2 3.8 6.2 4.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4611 PF15387.1 EAU90746.1 - 4.9 7.3 9.4 8.9 6.5 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.9 EAU90746.1 - 5.2 4.9 5.5 7 4.5 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIE-A_C-term PF11521.3 EAU90746.1 - 8.4 6.4 11.1 17 5.4 7.7 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Ran_BP1 PF00638.13 EAU90747.2 - 0.00067 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain F-box-like PF12937.2 EAU90749.2 - 0.047 13.4 0.4 0.13 11.9 0.3 1.8 1 0 0 1 1 1 0 F-box-like CRISPR_Cse2 PF09485.5 EAU90750.2 - 0.0059 16.6 2.2 0.0061 16.6 0.0 2.2 3 0 0 3 3 3 1 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4544 PF15077.1 EAU90750.2 - 1.9 7.9 5.6 1 8.8 2.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4544) HPHLAWLY PF14925.1 EAU90751.1 - 0.032 12.2 5.2 0.05 11.5 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function DPPIV_N PF00930.16 EAU90752.2 - 6.5e-94 314.4 0.2 8.6e-94 314.0 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EAU90752.2 - 1.1e-44 152.2 0.7 1.8e-44 151.5 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EAU90752.2 - 2.9e-08 33.5 0.1 6.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EAU90752.2 - 3.4e-07 29.9 2.3 6.4e-07 29.0 1.0 1.8 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EAU90752.2 - 1.9e-06 27.9 0.0 8.2e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU90752.2 - 0.007 15.9 0.2 0.067 12.7 0.0 2.3 2 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EAU90752.2 - 0.023 14.1 0.0 0.62 9.4 0.0 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 EAU90752.2 - 0.1 11.0 0.1 1 7.7 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 EAU90752.2 - 0.12 11.6 0.1 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.9 EAU90752.2 - 0.17 11.0 0.6 0.4 9.8 0.1 1.7 2 0 0 2 2 2 0 Secretory lipase SYS1 PF09801.4 EAU90753.1 - 5.1e-24 84.9 2.9 1.2e-16 60.9 1.3 2.0 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Tol_Tol_Ttg2 PF05494.7 EAU90754.2 - 0.16 11.5 0.0 0.38 10.2 0.0 1.6 1 1 1 2 2 2 0 Toluene tolerance, Ttg2 MinE PF03776.9 EAU90757.1 - 0.051 13.0 0.5 0.086 12.3 0.4 1.3 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Med3 PF11593.3 EAU90757.1 - 1 8.5 6.2 1.4 8.1 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CHAT PF12770.2 EAU90758.2 - 2e-27 96.0 0.0 3.9e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU90758.2 - 1.5e-26 92.0 0.2 0.011 15.7 0.0 11.0 4 2 8 12 12 12 9 Tetratricopeptide repeat TPR_10 PF13374.1 EAU90758.2 - 6e-17 60.9 4.9 0.37 10.7 0.0 10.3 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90758.2 - 2.9e-16 58.8 2.3 0.19 11.3 0.0 9.4 4 2 5 10 10 10 5 TPR repeat TPR_1 PF00515.23 EAU90758.2 - 0.0053 16.3 0.6 24 4.7 0.1 7.1 9 0 0 9 9 9 1 Tetratricopeptide repeat CHAT PF12770.2 EAU90759.2 - 4.2e-27 95.0 0.0 8.3e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU90759.2 - 1.1e-23 82.8 2.5 0.083 12.8 0.0 10.3 3 2 7 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.1 EAU90759.2 - 1.4e-15 56.6 17.5 0.04 13.8 0.0 10.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90759.2 - 0.001 18.8 5.6 6.7 6.8 0.0 7.5 9 0 0 9 9 9 1 Tetratricopeptide repeat Flu_NS2 PF00601.14 EAU90759.2 - 0.18 12.0 3.7 86 3.4 0.0 5.7 8 0 0 8 8 8 0 Influenza non-structural protein (NS2) TPR_12 PF13424.1 EAU90760.2 - 1.4e-51 172.3 1.0 0.013 15.3 0.0 16.9 2 1 15 17 17 17 13 Tetratricopeptide repeat TPR_10 PF13374.1 EAU90760.2 - 5.9e-42 140.4 30.1 0.0014 18.5 0.0 16.6 18 0 0 18 18 18 10 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90760.2 - 7.1e-28 96.0 8.3 0.093 12.3 0.0 15.5 4 1 15 19 19 19 10 TPR repeat CHAT PF12770.2 EAU90760.2 - 3.2e-27 95.4 0.0 6.7e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.1 EAU90760.2 - 5.9e-22 75.9 3.3 9.4 6.7 0.0 14.2 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU90760.2 - 3.2e-10 40.4 0.9 5.5 7.7 0.0 10.6 8 2 3 11 11 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU90760.2 - 5.1e-08 32.2 16.1 17 5.6 0.0 14.2 19 0 0 19 19 18 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90760.2 - 0.00034 20.0 10.2 48 3.8 0.0 11.1 14 0 0 14 14 14 0 Tetratricopeptide repeat Flu_NS2 PF00601.14 EAU90760.2 - 0.0013 18.8 5.4 88 3.4 0.0 8.1 9 0 0 9 9 9 0 Influenza non-structural protein (NS2) MIT PF04212.13 EAU90760.2 - 0.0021 17.8 0.9 61 3.5 0.0 6.3 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain Coleoptericin PF06286.6 EAU90760.2 - 0.0025 17.7 0.0 15 5.4 0.0 4.6 4 0 0 4 4 4 0 Coleoptericin DnaB_bind PF10410.4 EAU90760.2 - 0.081 12.9 5.7 1.2e+02 2.7 0.0 6.8 8 0 0 8 8 7 0 DnaB-helicase binding domain of primase DeoC PF01791.4 EAU90761.2 - 3.9e-37 127.8 1.1 1.3e-36 126.0 0.8 1.7 1 1 0 1 1 1 1 DeoC/LacD family aldolase zf-HC5HC2H_2 PF13832.1 EAU90763.2 - 3.5e-33 113.8 4.8 3.5e-33 113.8 3.3 2.7 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EAU90763.2 - 8.8e-25 86.6 2.3 8.8e-25 86.6 1.6 3.6 4 0 0 4 4 4 1 PHD-like zinc-binding domain EPL1 PF10513.4 EAU90763.2 - 1.3e-21 77.5 3.1 1.3e-21 77.5 2.2 3.1 4 1 0 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.20 EAU90763.2 - 6.4e-17 61.2 0.2 1.3e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 EAU90763.2 - 3.2e-15 55.1 2.7 3.2e-15 55.1 1.9 3.0 3 0 0 3 3 3 2 PHD-finger PWWP PF00855.12 EAU90763.2 - 8.6e-15 54.7 1.4 3.8e-14 52.6 0.9 2.2 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 EAU90763.2 - 3.1e-10 39.5 23.0 1.2e-09 37.6 4.0 3.6 4 0 0 4 4 4 2 PHD-finger C1_1 PF00130.17 EAU90763.2 - 0.0084 15.8 0.3 0.0084 15.8 0.2 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EAU90763.2 - 3.5 7.7 22.1 1.6 8.8 4.4 3.4 2 1 1 3 3 3 0 RING-like domain FYVE_2 PF02318.11 EAU90763.2 - 9 6.2 11.0 0.068 13.0 1.0 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger APH PF01636.18 EAU90764.1 - 0.00034 20.4 4.9 0.41 10.3 0.6 3.5 2 2 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EAU90764.1 - 0.0021 17.4 0.0 0.5 9.6 0.0 2.9 3 0 0 3 3 3 2 RIO1 family Pkinase PF00069.20 EAU90764.1 - 0.079 12.1 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain Daxx PF03344.10 EAU90764.1 - 0.65 8.4 45.6 0.53 8.7 10.6 2.3 2 0 0 2 2 2 0 Daxx Family Histone PF00125.19 EAU90765.2 - 1.1e-20 73.5 0.1 2.1e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EAU90765.2 - 0.0012 18.8 0.1 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EAU90765.2 - 0.0039 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF1931 PF09123.6 EAU90765.2 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Mis12 PF05859.7 EAU90766.1 - 1.3e-24 86.6 0.0 1.9e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Mis12 protein Lzipper-MIP1 PF14389.1 EAU90766.1 - 0.003 17.6 2.5 0.003 17.6 1.8 1.8 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Tnp_P_element PF12017.3 EAU90766.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Transposase protein Syntaxin-6_N PF09177.6 EAU90766.1 - 0.049 14.0 0.1 13 6.2 0.0 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal EAP30 PF04157.11 EAU90766.1 - 0.065 12.3 0.6 0.16 11.1 0.4 1.6 2 0 0 2 2 2 0 EAP30/Vps36 family p450 PF00067.17 EAU90768.2 - 1.4e-44 152.3 0.1 1.9e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EAU90769.1 - 0.00078 19.1 0.4 0.0015 18.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like FMN_red PF03358.10 EAU90770.1 - 7.9e-10 38.4 0.1 1.1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EAU90770.1 - 1.8e-09 37.7 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EAU90770.1 - 0.0078 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold DUF1900 PF08954.6 EAU90771.1 - 3.6e-48 162.5 0.0 1.9e-47 160.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EAU90771.1 - 2.1e-26 91.3 0.1 3.7e-26 90.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EAU90771.1 - 2.7e-24 84.1 1.9 4e-07 29.6 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat CCDC144C PF14915.1 EAU90771.1 - 0.26 10.1 2.9 0.38 9.6 2.0 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region GCV_T PF01571.16 EAU90772.1 - 5.4e-65 218.7 0.0 6.8e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EAU90772.1 - 3.7e-27 94.1 0.2 9.2e-27 92.9 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EAU90772.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Sarcosine oxidase, gamma subunit family TPR_12 PF13424.1 EAU90774.2 - 1.1e-18 66.9 0.4 0.083 12.8 0.1 10.5 5 2 6 12 12 12 4 Tetratricopeptide repeat TPR_11 PF13414.1 EAU90774.2 - 1.3e-13 50.3 4.6 0.28 10.8 0.1 8.4 3 2 4 8 8 8 4 TPR repeat TPR_10 PF13374.1 EAU90774.2 - 8.7e-13 47.7 9.7 4.5e-05 23.2 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU90774.2 - 0.00019 20.9 0.3 16 5.5 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EAU90774.2 - 0.0012 18.3 4.0 7.9 6.2 0.0 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU90774.2 - 0.0054 17.3 0.2 29 5.4 0.0 6.1 5 2 0 5 5 5 0 Tetratricopeptide repeat ActA PF05058.7 EAU90774.2 - 0.03 12.3 0.3 6.9 4.5 0.0 3.0 3 0 0 3 3 3 0 ActA Protein ECM1 PF05782.6 EAU90774.2 - 0.031 12.9 0.0 0.062 12.0 0.0 1.4 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) TPR_2 PF07719.12 EAU90774.2 - 0.76 9.8 10.3 1.5e+02 2.6 0.0 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Zn_clus PF00172.13 EAU90780.2 - 3.3e-08 33.2 13.6 6.9e-08 32.2 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_3 PF07969.6 EAU90782.2 - 1.1e-47 163.1 0.0 5.4e-40 137.8 0.0 2.0 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 EAU90782.2 - 7e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family zf-RING_6 PF14835.1 EAU90783.1 - 0.095 12.4 0.4 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein NifW PF03206.9 EAU90783.1 - 0.099 12.7 0.1 23 5.1 0.0 2.5 2 0 0 2 2 2 0 Nitrogen fixation protein NifW HTH_OrfB_IS605 PF12323.3 EAU90783.1 - 0.12 11.6 0.0 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain GYF PF02213.11 EAU90783.1 - 0.16 11.5 2.5 11 5.6 0.0 2.6 2 0 0 2 2 2 0 GYF domain Senescence_reg PF04520.8 EAU90785.2 - 1.6 9.2 8.8 0.3 11.5 0.3 3.1 3 0 0 3 3 3 0 Senescence regulator Cu-oxidase PF00394.17 EAU90786.2 - 1.7e-46 158.0 0.0 3.5e-42 144.0 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU90786.2 - 2e-34 117.8 0.3 2.8e-33 114.1 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU90786.2 - 1.8e-33 114.9 6.7 2.7e-32 111.1 0.1 3.5 2 1 0 2 2 2 2 Multicopper oxidase Nab1 PF04902.7 EAU90788.1 - 0.41 10.1 2.7 1.2 8.5 0.2 2.2 2 0 0 2 2 2 0 Conserved region in Nab1 DUF2201_N PF13203.1 EAU90788.1 - 0.46 9.5 3.1 0.2 10.8 0.4 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain HSP70 PF00012.15 EAU90789.1 - 1.9e-155 518.2 17.7 1.7e-147 491.9 0.2 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EAU90789.1 - 2e-10 39.7 0.5 6.2e-10 38.1 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein HsbA PF12296.3 EAU90789.1 - 0.12 12.2 3.3 2 8.2 0.1 3.2 3 0 0 3 3 3 0 Hydrophobic surface binding protein A BTB PF00651.26 EAU90790.2 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Cu_amine_oxidN1 PF07833.6 EAU90790.2 - 0.095 13.0 0.0 1.6 9.1 0.0 2.4 1 1 1 2 2 2 0 Copper amine oxidase N-terminal domain BTB PF00651.26 EAU90792.2 - 9.7e-05 22.3 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3505 PF12013.3 EAU90794.1 - 0.026 14.7 3.5 0.059 13.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) E7 PF00527.13 EAU90794.1 - 1.5 8.9 4.3 0.69 10.1 0.4 2.2 2 0 0 2 2 2 0 E7 protein, Early protein YppG PF14179.1 EAU90794.1 - 4.7 7.8 17.5 0.68 10.5 8.8 1.9 2 0 0 2 2 2 0 YppG-like protein zf-C2H2_4 PF13894.1 EAU90794.1 - 6 7.4 9.5 1.8 9.0 1.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Trypan_PARP PF05887.6 EAU90794.1 - 7.6 6.3 40.2 0.045 13.5 3.8 3.4 3 1 1 4 4 4 0 Procyclic acidic repetitive protein (PARP) TGT_C2 PF14810.1 EAU90795.1 - 0.073 12.9 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase MFS_1 PF07690.11 EAU90796.2 - 2e-24 85.9 41.0 3.3e-24 85.2 25.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily G-alpha PF00503.15 EAU90798.2 - 7.4e-97 324.4 0.1 9.2e-97 324.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU90798.2 - 7e-14 51.4 1.1 3.5e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EAU90798.2 - 0.00039 20.8 0.0 0.31 11.5 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EAU90798.2 - 0.00084 18.5 0.8 0.15 11.2 0.0 2.7 3 0 0 3 3 3 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU90798.2 - 0.0093 15.9 0.0 4.7 7.2 0.0 2.3 1 1 1 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EAU90798.2 - 0.024 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EAU90798.2 - 0.091 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3796 PF12676.2 EAU90799.1 - 1.1 9.4 7.0 0.21 11.8 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) Vma12 PF11712.3 EAU90801.1 - 2.7 7.6 5.3 88 2.7 3.7 2.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PMP1_2 PF08114.6 EAU90802.2 - 0.0089 15.4 0.2 1.1 8.8 0.0 2.7 2 0 0 2 2 2 2 ATPase proteolipid family Beta-lactamase PF00144.19 EAU90805.1 - 1.7e-21 76.6 0.8 4.8e-21 75.1 0.5 1.7 1 0 0 1 1 1 1 Beta-lactamase DEAD PF00270.24 EAU90806.1 - 0.0029 17.1 0.0 0.0044 16.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU90806.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EAU90806.1 - 0.15 11.3 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain DUF3357 PF11837.3 EAU90809.2 - 0.06 13.2 0.1 5.2 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF1656 PF07869.7 EAU90809.2 - 0.99 9.2 8.3 0.98 9.2 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Pyr_redox_3 PF13738.1 EAU90810.2 - 2.7e-22 79.8 0.0 1.3e-21 77.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAU90810.2 - 9.1e-18 63.7 0.1 7.2e-13 47.5 0.2 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EAU90810.2 - 9.1e-10 37.9 0.1 1.6e-05 23.9 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EAU90810.2 - 1.1e-09 38.5 0.0 2.6e-08 33.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU90810.2 - 1e-07 32.2 0.1 0.00038 20.8 0.0 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU90810.2 - 8.2e-05 22.5 0.0 0.00052 19.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EAU90810.2 - 0.00063 18.8 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAU90810.2 - 0.0051 15.7 0.1 0.16 10.8 0.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EAU90810.2 - 0.0072 15.4 0.1 0.093 11.8 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EAU90810.2 - 0.028 12.8 0.0 0.086 11.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EAU90810.2 - 0.041 12.7 0.0 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EAU90810.2 - 0.088 11.6 0.0 0.31 9.8 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EAU90810.2 - 0.093 11.8 0.1 0.32 10.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EAU90810.2 - 0.11 11.3 0.1 0.21 10.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EAU90810.2 - 0.2 11.3 0.1 9.7 5.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EAU90811.1 - 6.9e-24 85.0 0.0 5.4e-23 82.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EAU90811.1 - 5e-19 67.8 0.0 3.8e-13 48.4 0.0 2.7 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EAU90811.1 - 1.8e-11 43.5 0.1 3.6e-06 26.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EAU90811.1 - 2.3e-11 43.9 0.0 6.9e-10 39.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EAU90811.1 - 2.8e-07 30.8 0.2 0.00039 20.7 0.0 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EAU90811.1 - 0.0001 22.2 0.0 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EAU90811.1 - 0.00074 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EAU90811.1 - 0.01 14.7 0.1 0.16 10.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EAU90811.1 - 0.012 14.7 0.0 0.096 11.8 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EAU90811.1 - 0.026 13.0 0.0 0.088 11.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EAU90811.1 - 0.047 12.6 0.0 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EAU90811.1 - 0.076 12.7 0.7 11 5.7 0.1 3.3 3 1 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EAU90811.1 - 0.081 11.7 0.1 0.21 10.3 0.1 1.7 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EAU90811.1 - 0.086 11.6 0.0 0.32 9.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EAU90811.1 - 0.093 11.8 0.1 0.33 9.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family RmuC PF02646.11 EAU90812.2 - 0.15 10.8 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 RmuC family PIG-P PF08510.7 EAU90813.2 - 0.013 15.0 6.0 0.041 13.5 4.2 1.8 1 0 0 1 1 1 0 PIG-P FAD_binding_4 PF01565.18 EAU90814.2 - 2.5e-29 101.5 3.5 3.9e-29 100.8 2.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU90814.2 - 2.1e-10 40.3 0.1 3.9e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EAU90815.1 - 4.5e-32 110.4 2.8 7.8e-32 109.6 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EAU90815.1 - 1.5e-16 60.0 1.3 2.6e-16 59.2 0.9 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EAU90815.1 - 0.049 12.7 0.1 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding H_lectin PF09458.5 EAU90816.2 - 1.5e-32 111.0 1.1 4.1e-15 55.1 0.0 4.2 4 0 0 4 4 4 3 H-type lectin domain zf-MYND PF01753.13 EAU90818.2 - 2.4e-08 33.6 10.4 5e-08 32.6 7.2 1.5 1 0 0 1 1 1 1 MYND finger Lipase_GDSL_2 PF13472.1 EAU90819.1 - 5.3e-18 65.7 0.5 9.1e-18 65.0 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU90819.1 - 7.9e-16 58.5 0.2 4.7e-15 56.0 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-MYND PF01753.13 EAU90821.1 - 1.4e-07 31.2 7.1 2.9e-07 30.2 4.9 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EAU90822.2 - 1.4e-08 34.4 9.1 3e-08 33.3 6.3 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EAU90823.2 - 1.7e-10 40.5 6.9 2.9e-10 39.8 4.8 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU90823.2 - 0.059 12.6 1.5 0.12 11.6 1.0 1.5 1 0 0 1 1 1 0 Life-span regulatory factor PWWP PF00855.12 EAU90824.1 - 2.2e-18 66.2 0.9 5.5e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 EAU90824.1 - 0.00013 21.3 0.0 0.00033 20.1 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain MIP-T3 PF10243.4 EAU90824.1 - 0.52 8.7 31.3 0.6 8.5 16.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 FLYWCH PF04500.11 EAU90825.2 - 0.12 12.2 2.5 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 FLYWCH zinc finger domain Tet_JBP PF12851.2 EAU90827.1 - 5e-06 25.9 0.0 7.3e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EAU90829.2 - 0.061 13.8 0.1 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Nop14 PF04147.7 EAU90833.1 - 0.11 10.3 4.3 0.14 10.0 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_UL43 PF05072.8 EAU90833.1 - 0.18 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL43 protein PBP1_TM PF14812.1 EAU90833.1 - 1.6 9.0 5.6 0.39 11.0 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM163 PF15069.1 EAU90833.1 - 2.6 8.6 5.9 1.7 9.1 0.0 2.7 1 1 2 3 3 3 0 FAM163 family DUF202 PF02656.10 EAU90834.2 - 2.7e-15 56.3 4.4 2.7e-15 56.3 3.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Claudin_2 PF13903.1 EAU90834.2 - 2.2 7.9 6.3 3.4 7.3 4.4 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Phage_integrase PF00589.17 EAU90846.1 - 1.3e-05 24.9 0.1 0.0002 21.0 0.1 2.7 2 1 0 2 2 2 1 Phage integrase family F-box PF00646.28 EAU90847.2 - 0.05 13.2 0.2 0.19 11.4 0.1 2.0 1 0 0 1 1 1 0 F-box domain PSK_trans_fac PF07704.6 EAU90848.1 - 0.48 11.1 4.8 0.77 10.4 0.6 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor F-box-like PF12937.2 EAU90849.2 - 0.0072 16.0 0.2 0.017 14.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU90849.2 - 0.025 14.2 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 F-box domain GATase_5 PF13507.1 EAU90850.2 - 3.4e-99 330.9 0.1 1.3e-98 329.0 0.0 2.0 3 0 0 3 3 3 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EAU90850.2 - 3.6e-47 160.1 1.7 9.2e-26 90.6 0.2 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EAU90850.2 - 5.8e-24 84.1 0.0 2.9e-23 81.9 0.0 2.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ETX_MTX2 PF03318.8 EAU90851.2 - 1.8e-08 34.2 6.7 2.8e-08 33.5 4.4 1.5 1 1 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 EAU90851.2 - 4.1e-08 32.5 0.6 1.4e-07 30.8 0.9 1.4 2 0 0 2 2 2 1 Aerolysin toxin F-box-like PF12937.2 EAU90852.1 - 0.0008 19.0 0.1 0.0022 17.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Use1 PF09753.4 EAU90853.1 - 1.3e-10 41.2 0.4 1.3e-10 41.2 0.3 1.5 2 0 0 2 2 2 1 Membrane fusion protein Use1 XhlA PF10779.4 EAU90853.1 - 1.5 8.7 5.1 2.1 8.3 0.5 2.6 2 0 0 2 2 2 0 Haemolysin XhlA GP41 PF00517.12 EAU90853.1 - 2.3 7.7 5.3 2 7.9 0.7 2.7 3 1 0 3 3 3 0 Retroviral envelope protein DUF3951 PF13131.1 EAU90853.1 - 9.5 6.0 6.9 15 5.4 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) zf-DBF PF07535.7 EAU90854.1 - 0.0082 15.8 0.2 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 DBF zinc finger F-box-like PF12937.2 EAU90855.2 - 0.31 10.8 6.8 0.14 11.9 0.4 3.2 3 0 0 3 3 3 0 F-box-like BUD22 PF09073.5 EAU90857.2 - 0.19 10.7 12.6 0.23 10.4 8.7 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.4 EAU90857.2 - 0.57 8.4 4.8 0.58 8.3 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein AF-4 PF05110.8 EAU90857.2 - 1.3 6.7 18.5 1.9 6.2 12.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.4 EAU90857.2 - 2 7.1 6.4 2.3 6.9 4.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.6 EAU90857.2 - 3.7 5.5 9.9 3.7 5.5 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nop14 PF04147.7 EAU90857.2 - 7.1 4.4 13.6 8.6 4.1 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family BTB PF00651.26 EAU90858.2 - 0.00019 21.3 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Baculo_DNA_bind PF04786.7 EAU90858.2 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 ssDNA binding protein Lipase_GDSL_2 PF13472.1 EAU90859.1 - 3.4e-17 63.1 0.2 5e-17 62.5 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU90859.1 - 1.3e-15 57.9 0.0 2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nucleoporin_FG PF13634.1 EAU90860.2 - 0.011 15.8 29.9 0.027 14.6 20.7 1.6 1 1 0 1 1 1 0 Nucleoporin FG repeat region bZIP_1 PF00170.16 EAU90862.2 - 5.1e-09 35.9 14.2 1.7e-08 34.3 6.9 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EAU90862.2 - 2.4e-08 33.6 11.2 2.4e-08 33.6 7.8 2.7 3 0 0 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.12 EAU90862.2 - 0.19 12.0 12.3 0.062 13.5 5.5 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor Arrestin_C PF02752.17 EAU90866.2 - 1e-12 48.3 0.2 4.5e-12 46.2 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EAU90866.2 - 4.2e-08 33.1 0.0 1.1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EAU90866.2 - 3.8e-05 23.2 0.0 6.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF3099 PF11298.3 EAU90868.1 - 2.8 7.7 8.7 0.36 10.5 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) DUF996 PF06195.8 EAU90868.1 - 7.4 6.5 12.6 1 9.3 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF996) Peptidase_M43 PF05572.8 EAU90870.1 - 6.6e-18 64.7 0.0 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU90870.1 - 5.5e-05 23.1 0.4 5.5e-05 23.1 0.3 1.5 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU90870.1 - 0.00043 19.8 0.1 0.0007 19.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU90870.1 - 0.00063 19.8 0.1 0.00088 19.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EAU90870.1 - 0.0018 17.2 0.5 0.0027 16.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.1 EAU90870.1 - 0.0048 17.4 0.1 0.011 16.2 0.1 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EAU90870.1 - 0.01 15.2 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EAU90870.1 - 0.1 12.3 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Matrixin HIT PF01230.18 EAU90870.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 HIT domain OCD_Mu_crystall PF02423.10 EAU90871.2 - 0.073 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Abhydrolase_6 PF12697.2 EAU90872.2 - 4e-14 53.0 0.2 6.7e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family peroxidase PF00141.18 EAU90873.1 - 2.4e-49 167.9 0.0 3.6e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase NACHT PF05729.7 EAU90874.1 - 1.2e-09 38.1 0.4 5.9e-09 35.8 0.3 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU90874.1 - 0.019 15.0 0.2 0.15 12.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EAU90874.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EAU90874.1 - 0.15 12.0 5.7 0.066 13.1 1.5 2.3 2 1 0 2 2 2 0 AAA ATPase domain DivIC PF04977.10 EAU90877.2 - 0.0044 16.4 0.7 0.11 12.0 0.1 2.2 1 1 1 2 2 2 2 Septum formation initiator DUF605 PF04652.11 EAU90877.2 - 2.2 7.5 9.3 2.9 7.1 6.4 1.2 1 0 0 1 1 1 0 Vta1 like EcKinase PF02958.15 EAU90878.2 - 0.0034 16.5 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DivIC PF04977.10 EAU90878.2 - 0.0034 16.8 0.7 0.096 12.1 0.1 2.2 1 1 1 2 2 2 2 Septum formation initiator DUF605 PF04652.11 EAU90878.2 - 4.3 6.6 5.6 5.7 6.2 3.9 1.2 1 0 0 1 1 1 0 Vta1 like zf-CCHC PF00098.18 EAU90882.1 - 1.3e-10 40.6 26.6 0.00087 19.1 0.8 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EAU90882.1 - 2.5e-08 33.2 15.9 0.0029 17.0 0.0 4.2 2 1 2 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 EAU90882.1 - 0.011 15.4 23.2 0.41 10.3 0.6 4.4 4 0 0 4 4 4 0 Zinc knuckle Amnionless PF14828.1 EAU90882.1 - 1.8 6.9 8.3 3.3 6.1 5.8 1.4 1 0 0 1 1 1 0 Amnionless GPCR_chapero_1 PF11904.3 EAU90882.1 - 6.5 5.7 11.1 7.8 5.5 6.4 1.8 2 0 0 2 2 2 0 GPCR-chaperone Proteasome PF00227.21 EAU90883.2 - 8e-54 181.8 0.0 1.4e-53 181.0 0.0 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAU90883.2 - 2.4e-14 52.3 0.2 4.1e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Sialidase PF02973.11 EAU90884.1 - 0.013 14.4 0.2 0.021 13.7 0.1 1.3 1 0 0 1 1 1 0 Sialidase, N-terminal domain HSP70 PF00012.15 EAU90884.1 - 0.18 9.6 0.3 0.53 8.1 0.2 1.7 1 1 0 1 1 1 0 Hsp70 protein DPBB_1 PF03330.13 EAU90886.1 - 0.003 17.5 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1998 PF09369.5 EAU90886.1 - 0.014 15.9 0.1 0.022 15.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1998) 4HBT_3 PF13622.1 EAU90886.1 - 3.1 7.4 12.2 1.5 8.5 6.7 1.7 2 0 0 2 2 2 0 Thioesterase-like superfamily SKI PF01202.17 EAU90887.1 - 1.5e-09 37.8 0.0 1.4e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.1 EAU90887.1 - 1.9e-08 34.6 0.0 4e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU90887.1 - 4e-07 30.0 0.0 2.5e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU90887.1 - 4.3e-06 27.5 0.0 5.9e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU90887.1 - 0.00011 22.2 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EAU90887.1 - 0.0039 16.1 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EAU90887.1 - 0.0053 17.0 0.0 0.0091 16.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EAU90887.1 - 0.0061 16.7 0.1 0.041 14.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EAU90887.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EAU90887.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.1 EAU90887.1 - 0.036 14.0 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EAU90887.1 - 0.047 13.2 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EAU90887.1 - 0.097 12.8 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 EAU90887.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Thymidylate_kin PF02223.12 EAU90887.1 - 0.12 11.7 0.1 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase RNA_helicase PF00910.17 EAU90887.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Fungal_trans PF04082.13 EAU90888.1 - 1.1e-24 86.6 0.0 2e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU90888.1 - 0.0021 17.9 1.3 0.0021 17.9 0.9 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps53_N PF04100.7 EAU90891.1 - 1e-94 317.4 7.8 1.9e-94 316.6 5.4 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EAU90891.1 - 1e-07 31.1 7.2 1e-07 31.1 5.0 1.7 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EAU90891.1 - 4.2e-05 23.3 5.6 0.00014 21.6 3.9 1.9 1 0 0 1 1 1 1 Exocyst complex component Sec5 Cob_adeno_trans PF01923.13 EAU90891.1 - 0.12 12.1 2.8 0.47 10.2 2.0 2.0 1 1 0 1 1 1 0 Cobalamin adenosyltransferase DUF1664 PF07889.7 EAU90891.1 - 0.13 12.0 9.8 0.18 11.5 3.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EAU90891.1 - 0.66 9.5 8.8 1.1 8.7 5.5 1.8 1 1 0 1 1 1 0 IncA protein Yippee-Mis18 PF03226.9 EAU90892.1 - 7.9e-17 61.0 0.0 1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ctr PF04145.10 EAU90893.2 - 9.6e-36 122.9 0.2 1.2e-35 122.7 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF747 PF05346.6 EAU90893.2 - 0.0048 15.9 0.1 0.006 15.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family HSP70 PF00012.15 EAU90894.2 - 0.12 10.2 0.0 0.93 7.3 0.0 2.0 2 0 0 2 2 2 0 Hsp70 protein TrwB_AAD_bind PF10412.4 EAU90894.2 - 0.15 10.6 0.2 0.67 8.5 0.0 2.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain IL31 PF15209.1 EAU90897.1 - 0.002 17.7 1.0 0.0046 16.5 0.7 1.6 1 0 0 1 1 1 1 Interleukin 31 Noelin-1 PF12308.3 EAU90897.1 - 0.078 12.7 0.5 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein APG6 PF04111.7 EAU90897.1 - 0.18 10.7 10.1 0.25 10.3 3.4 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF2408 PF10303.4 EAU90897.1 - 0.22 11.6 9.2 1.6 8.8 2.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) FlaC_arch PF05377.6 EAU90897.1 - 0.94 9.4 5.0 11 5.9 0.0 4.1 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) FliT PF05400.8 EAU90897.1 - 1.8 9.0 19.2 0.32 11.4 0.6 4.3 4 0 0 4 4 4 0 Flagellar protein FliT Med9 PF07544.8 EAU90897.1 - 4.3 7.1 12.5 2.4 7.9 1.3 3.5 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 COG5 PF10392.4 EAU90897.1 - 7 6.6 16.2 0.27 11.2 1.6 3.6 3 1 0 4 4 4 0 Golgi transport complex subunit 5 DUF342 PF03961.8 EAU90897.1 - 8.2 4.7 10.1 2.3 6.5 2.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Peptidase_S8 PF00082.17 EAU90898.2 - 8.4e-51 172.7 0.6 1.3e-50 172.2 0.4 1.2 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EAU90898.2 - 3.6e-12 46.6 0.1 7.2e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EAU90898.2 - 7.9e-08 31.9 0.0 5.3e-07 29.2 0.0 2.4 2 0 0 2 2 2 1 PA domain Peptidase_S8 PF00082.17 EAU90899.2 - 1.1e-54 185.5 0.7 1.1e-54 185.5 0.5 1.5 2 0 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 EAU90899.2 - 1.5e-11 44.6 0.1 5.5e-11 42.8 0.1 1.9 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EAU90899.2 - 1.9e-06 27.4 0.0 5.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 PA domain NPCBM_assoc PF10633.4 EAU90899.2 - 0.019 15.0 0.5 0.18 11.8 0.2 2.7 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase FixG_C PF11614.3 EAU90899.2 - 0.099 12.7 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Kelch_4 PF13418.1 EAU90900.2 - 4.8e-31 106.2 8.7 1.2e-08 34.5 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Muskelin_N PF06588.6 EAU90900.2 - 2.7e-26 92.5 0.0 4.4e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_3 PF13415.1 EAU90900.2 - 4e-24 84.1 13.5 1.5e-06 28.2 0.0 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EAU90900.2 - 6.5e-24 83.4 4.5 5.1e-07 29.5 0.0 6.3 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.20 EAU90900.2 - 7.7e-21 73.3 2.4 1.5e-06 27.6 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EAU90900.2 - 1.7e-19 69.0 7.0 0.00061 19.8 0.0 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.10 EAU90900.2 - 4.7e-09 35.6 0.7 0.00012 21.6 0.1 4.2 3 0 0 3 3 3 2 Kelch motif CLTH PF10607.4 EAU90900.2 - 0.042 13.5 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain RAG2 PF03089.9 EAU90900.2 - 0.063 12.0 0.0 21 3.6 0.0 3.2 3 0 0 3 3 3 0 Recombination activating protein 2 7tm_1 PF00001.16 EAU90901.2 - 2.6e-05 23.4 4.3 3.5e-05 23.0 3.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 EAU90901.2 - 0.00083 18.9 9.9 0.0023 17.5 6.8 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EAU90901.2 - 0.0071 16.0 0.2 0.0071 16.0 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term CHZ PF09649.5 EAU90904.1 - 2.4e-08 33.0 0.2 2.4e-08 33.0 0.2 2.8 2 1 0 2 2 1 1 Histone chaperone domain CHZ CDC27 PF09507.5 EAU90904.1 - 0.14 11.3 8.4 0.14 11.3 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM176 PF14851.1 EAU90904.1 - 0.23 11.1 9.7 0.14 11.7 5.7 1.5 1 1 0 1 1 1 0 FAM176 family Daxx PF03344.10 EAU90904.1 - 0.33 9.4 14.9 0.32 9.4 10.4 1.2 1 0 0 1 1 1 0 Daxx Family Paf1 PF03985.8 EAU90904.1 - 0.55 8.9 9.9 0.56 8.8 6.9 1.1 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.7 EAU90904.1 - 0.69 9.1 17.9 0.76 8.9 12.4 1.1 1 0 0 1 1 1 0 SDA1 PTRF_SDPR PF15237.1 EAU90904.1 - 0.84 8.9 3.6 0.9 8.8 2.5 1.1 1 0 0 1 1 1 0 PTRF/SDPR family DUF2890 PF11081.3 EAU90904.1 - 1.4 8.9 9.3 1.5 8.8 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Trypan_PARP PF05887.6 EAU90904.1 - 1.7 8.4 9.8 2.8 7.7 6.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ANAPC15 PF15243.1 EAU90904.1 - 2.5 8.2 21.7 7.8 6.6 12.2 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Tim54 PF11711.3 EAU90904.1 - 2.6 6.5 4.9 2.8 6.4 3.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.6 EAU90904.1 - 3.4 5.6 7.9 3.3 5.7 5.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VID27 PF08553.5 EAU90904.1 - 3.4 5.7 9.8 3.8 5.6 6.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 EAU90904.1 - 3.5 5.5 10.9 3.2 5.6 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 EAU90904.1 - 4.9 6.9 13.2 0.57 9.9 5.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EAU90904.1 - 5.3 6.5 22.7 1.7 8.1 12.5 2.0 2 0 0 2 2 2 0 Nucleoplasmin Prothymosin PF03247.9 EAU90904.1 - 5.6 7.1 28.1 0.82 9.8 14.8 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family P12 PF12669.2 EAU90905.1 - 0.013 15.7 0.5 0.026 14.7 0.0 1.8 1 1 1 2 2 2 0 Virus attachment protein p12 family DUF912 PF06024.7 EAU90905.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CD34_antigen PF06365.7 EAU90905.1 - 0.019 14.6 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Rpr2 PF04032.11 EAU90906.1 - 4.5e-18 64.8 1.2 7e-18 64.2 0.9 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_4 PF13717.1 EAU90906.1 - 0.17 11.5 2.2 0.59 9.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EAU90906.1 - 0.21 11.2 2.2 0.61 9.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain F-box-like PF12937.2 EAU90907.1 - 4.9e-09 35.7 0.0 1.3e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 F-box-like BRE1 PF08647.6 EAU90907.1 - 0.0046 16.8 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase Atg14 PF10186.4 EAU90907.1 - 0.026 13.4 0.1 0.037 12.9 0.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 F-box PF00646.28 EAU90907.1 - 0.46 10.2 4.5 0.22 11.2 0.6 2.5 2 0 0 2 2 2 0 F-box domain Mito_fiss_reg PF05308.6 EAU90908.2 - 0.057 12.7 3.8 0.063 12.6 2.7 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-LYAR PF08790.6 EAU90910.1 - 3.7e-13 48.9 1.0 9.3e-13 47.6 0.7 1.8 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Autophagy_N PF03986.8 EAU90911.2 - 5.8e-44 149.3 1.6 9.2e-43 145.5 1.1 2.5 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EAU90911.2 - 6.5e-26 90.2 0.5 1.5e-25 89.1 0.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EAU90911.2 - 4.4e-12 44.8 3.2 7.8e-12 44.0 2.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Mago_nashi PF02792.9 EAU90911.2 - 0.018 14.7 0.1 0.068 12.8 0.0 1.9 2 0 0 2 2 2 0 Mago nashi protein DUF3774 PF12609.3 EAU90911.2 - 0.41 11.5 4.2 0.44 11.4 0.2 2.8 2 1 1 3 3 3 0 Wound-induced protein GHMP_kinases_N PF00288.21 EAU90912.1 - 3.1e-07 30.3 2.7 6.8e-07 29.2 1.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Mito_fiss_reg PF05308.6 EAU90914.2 - 0.035 13.4 0.8 0.03 13.6 0.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator F-box-like PF12937.2 EAU90915.2 - 0.00012 21.7 1.2 0.00034 20.2 0.1 2.5 2 0 0 2 2 2 1 F-box-like Pyridoxal_deC PF00282.14 EAU90916.2 - 3.3e-15 55.4 0.0 6.6e-15 54.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EAU90916.2 - 3e-07 29.5 0.0 2.9e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EAU90916.2 - 8.4e-05 21.7 0.2 0.00014 21.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EAU90916.2 - 0.00017 20.6 0.0 0.00029 19.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MBOAT_2 PF13813.1 EAU90917.2 - 5.2e-19 68.1 6.8 5.2e-19 68.1 4.7 2.3 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family RNase_T PF00929.19 EAU90918.1 - 4e-16 59.7 0.0 9.2e-16 58.5 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DUF4407 PF14362.1 EAU90919.2 - 2 7.2 5.8 2.9 6.7 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC27 PF09507.5 EAU90919.2 - 4.3 6.4 34.2 7.7 5.6 23.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glyoxalase PF00903.20 EAU90920.2 - 1.6e-23 83.1 0.1 1.8e-23 82.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EAU90920.2 - 6.9e-16 58.8 0.0 9.1e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EAU90920.2 - 2.8e-07 30.5 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EAU90920.2 - 0.0092 15.8 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain SynMuv_product PF06047.6 EAU90922.2 - 6.2e-43 144.8 6.0 6.2e-43 144.8 4.1 2.4 2 1 0 2 2 2 1 Ras-induced vulval development antagonist Git3 PF11710.3 EAU90923.2 - 2.9e-08 33.5 9.5 2.5e-07 30.4 6.6 2.1 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EAU90923.2 - 2.5e-07 30.1 5.5 4.4e-07 29.2 3.8 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.4 EAU90923.2 - 0.00021 20.4 1.8 0.00036 19.7 1.3 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv Git3_C PF11970.3 EAU90923.2 - 0.034 13.9 0.4 0.034 13.9 0.3 2.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term FixQ PF05545.6 EAU90923.2 - 0.11 12.1 3.6 0.21 11.2 0.0 2.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Totivirus_coat PF05518.6 EAU90924.1 - 0.21 9.3 0.6 0.27 9.0 0.4 1.0 1 0 0 1 1 1 0 Totivirus coat protein tRNA-synt_2 PF00152.15 EAU90925.1 - 3.8e-88 295.4 0.0 5e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAU90925.1 - 2.8e-12 46.2 0.0 7.4e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EAU90925.1 - 2.3e-08 33.5 0.0 0.00022 20.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EAU90925.1 - 0.0095 15.5 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_60s PF00428.14 EAU90925.1 - 0.7 10.3 8.2 1.8 9.0 5.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein MBOAT_2 PF13813.1 EAU90926.2 - 1.9e-22 79.1 3.4 1.9e-22 79.1 2.3 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family F-box-like PF12937.2 EAU90927.2 - 3.1e-07 29.9 0.4 7.9e-07 28.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU90927.2 - 0.023 14.3 0.5 0.023 14.3 0.4 3.2 4 1 0 4 4 4 0 F-box domain LRR_8 PF13855.1 EAU90927.2 - 1.4 8.6 5.9 15 5.4 0.0 3.5 4 0 0 4 4 4 0 Leucine rich repeat IBR PF01485.16 EAU90928.1 - 6.2e-10 38.8 45.4 1.2e-09 37.9 11.4 4.8 3 2 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EAU90928.1 - 3e-05 23.9 5.5 3e-05 23.9 3.8 4.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU90928.1 - 0.00017 21.3 30.1 0.0011 18.7 3.8 3.2 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EAU90928.1 - 0.00018 21.0 32.7 0.00029 20.4 3.5 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU90928.1 - 0.016 14.9 3.5 0.016 14.9 2.4 3.4 3 1 0 3 3 3 0 zinc-RING finger domain zf-RING_6 PF14835.1 EAU90928.1 - 0.18 11.6 18.4 0.42 10.4 0.1 3.9 4 0 0 4 4 4 0 zf-RING of BARD1-type protein LRR_8 PF13855.1 EAU90929.1 - 0.037 13.7 10.8 4.9 6.9 0.4 4.7 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EAU90929.1 - 0.25 10.9 5.1 12 5.6 0.0 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) G-alpha PF00503.15 EAU90930.1 - 1.6e-113 379.3 0.0 1e-112 376.7 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU90930.1 - 1e-08 34.6 1.3 0.24 10.6 0.1 3.9 4 0 0 4 4 4 3 ADP-ribosylation factor family AAA_29 PF13555.1 EAU90930.1 - 0.0063 16.0 0.1 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EAU90930.1 - 0.045 12.9 1.4 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.7 EAU90930.1 - 0.081 12.5 0.0 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Na_H_Exchanger PF00999.16 EAU90931.2 - 9.9e-53 179.0 42.0 1.4e-52 178.5 29.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CDC45 PF02724.9 EAU90931.2 - 0.084 10.9 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.2 EAU90932.1 - 0.0014 18.2 4.4 0.014 15.0 3.1 2.4 1 1 0 1 1 1 1 F-box-like Transp_Tc5_C PF04236.10 EAU90932.1 - 0.1 12.8 2.1 0.14 12.3 0.2 2.1 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Sec34 PF04136.10 EAU90936.2 - 4e-29 101.3 0.7 9.3e-29 100.1 0.5 1.6 1 0 0 1 1 1 1 Sec34-like family POX PF07526.6 EAU90936.2 - 0.0065 16.7 3.2 0.53 10.5 0.0 3.6 4 0 0 4 4 4 1 Associated with HOX Pox_P4B PF03292.9 EAU90936.2 - 0.011 13.7 0.0 0.017 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P4B major core protein FAM176 PF14851.1 EAU90936.2 - 0.049 13.3 0.8 0.12 12.0 0.5 1.6 1 0 0 1 1 1 0 FAM176 family Tom37_C PF11801.3 EAU90936.2 - 0.058 13.2 0.5 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain F-box-like PF12937.2 EAU90939.1 - 3.3e-09 36.3 0.4 1.7e-08 34.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like Atg14 PF10186.4 EAU90939.1 - 0.02 13.8 1.5 0.036 13.0 1.0 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PspA_IM30 PF04012.7 EAU90939.1 - 0.023 14.0 1.0 0.036 13.4 0.7 1.2 1 0 0 1 1 1 0 PspA/IM30 family Spc7 PF08317.6 EAU90939.1 - 0.028 13.0 2.6 0.05 12.2 1.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 EAU90939.1 - 0.045 13.5 1.3 0.087 12.5 0.9 1.4 1 0 0 1 1 1 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EAU90939.1 - 0.073 12.8 1.5 0.16 11.7 1.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.6 EAU90939.1 - 0.086 11.3 2.1 0.13 10.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) bZIP_1 PF00170.16 EAU90939.1 - 0.87 9.5 9.4 0.22 11.5 3.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor OsmC PF02566.14 EAU90940.1 - 3e-13 49.8 0.0 4.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Toxin_50 PF15530.1 EAU90940.1 - 0.11 12.4 0.6 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 50 CPSF_A PF03178.10 EAU90941.1 - 3e-96 322.3 0.0 1.3e-95 320.2 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EAU90941.1 - 8.9e-79 264.9 0.0 2.3e-78 263.5 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term MFS_1 PF07690.11 EAU90942.1 - 1.9e-34 118.9 23.1 1.9e-34 118.9 16.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EAU90942.1 - 0.003 17.2 0.2 0.046 13.5 0.0 2.8 2 1 0 2 2 2 1 MFS_1 like family DUF2530 PF10745.4 EAU90942.1 - 0.0083 16.0 0.7 0.039 13.9 0.5 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) DUF1616 PF07760.6 EAU90942.1 - 0.033 13.3 0.5 0.062 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) F-box-like PF12937.2 EAU90943.2 - 0.00019 21.0 0.4 0.0005 19.7 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU90944.2 - 2e-07 30.6 0.2 6e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU90944.2 - 0.0026 17.3 0.0 0.012 15.2 0.0 2.2 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 EAU90945.1 - 3.5e-33 114.7 30.4 5.7e-33 114.0 21.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 EAU90945.1 - 0.019 14.1 1.4 0.034 13.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Topoisom_bac PF01131.15 EAU90946.2 - 1.6e-85 287.4 0.0 2.1e-85 286.9 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EAU90946.2 - 2.2e-19 69.2 0.0 4.5e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.7 EAU90946.2 - 7.4e-18 64.2 10.7 1.3e-14 53.7 3.7 3.0 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.18 EAU90946.2 - 2.7e-14 52.3 20.0 1.1e-05 25.0 1.4 3.9 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_3 PF13917.1 EAU90946.2 - 2.9e-05 23.7 7.7 0.049 13.3 0.1 3.8 3 0 0 3 3 3 3 Zinc knuckle DUF1253 PF06862.7 EAU90947.2 - 2.1e-139 464.7 0.0 2.8e-139 464.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) PC-Esterase PF13839.1 EAU90950.2 - 4.6e-05 23.3 1.0 0.32 10.7 0.0 2.5 3 0 0 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DEAD PF00270.24 EAU90951.1 - 0.00087 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU90951.1 - 0.067 13.0 0.1 0.11 12.3 0.0 1.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EAU90951.1 - 0.069 12.4 0.0 0.069 12.4 0.0 1.1 1 0 0 1 1 1 0 SecA DEAD-like domain LRR_4 PF12799.2 EAU90953.2 - 3e-54 179.9 64.8 5.5e-10 38.6 0.8 13.0 7 3 7 16 16 16 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU90953.2 - 2.7e-47 158.3 64.4 2e-15 56.2 2.0 10.8 5 2 6 11 11 11 8 Leucine rich repeat PP2C PF00481.16 EAU90953.2 - 4.1e-45 154.1 0.0 7e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EAU90953.2 - 9.5e-27 88.9 62.4 0.02 14.8 0.0 19.2 20 0 0 20 20 20 11 Leucine Rich Repeat Guanylate_cyc PF00211.15 EAU90953.2 - 6.2e-23 81.1 0.0 1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EAU90953.2 - 2.4e-15 53.9 58.5 0.16 12.2 0.0 17.1 17 0 0 17 17 17 5 Leucine rich repeat LRR_5 PF13306.1 EAU90953.2 - 5.7e-06 26.0 0.3 0.98 9.1 0.0 4.2 3 1 2 5 5 5 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EAU90953.2 - 0.00041 19.9 12.1 0.096 12.2 0.1 4.7 3 2 1 4 4 4 2 Leucine-rich repeat RA PF00788.18 EAU90953.2 - 0.0066 16.9 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 EAU90953.2 - 0.022 14.7 68.4 3.6 7.9 0.0 16.2 19 0 0 19 19 19 0 Leucine Rich repeat HSP20 PF00011.16 EAU90954.1 - 1.1e-24 86.2 0.1 1.4e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EAU90954.1 - 0.0026 17.3 0.1 0.004 16.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4097) BON PF04972.12 EAU90954.1 - 0.041 13.6 0.1 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 BON domain F-box-like PF12937.2 EAU90955.1 - 1.2e-05 24.8 0.3 3.1e-05 23.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EAU90955.1 - 0.014 15.0 4.2 8.8 6.0 0.5 5.1 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Totivirus_coat PF05518.6 EAU90957.1 - 0.027 12.3 1.9 0.035 11.9 1.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein Malate_synthase PF01274.17 EAU90958.2 - 5.8e-202 671.3 0.0 7.4e-202 670.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase CHD5 PF04420.9 EAU90959.1 - 2.5e-47 160.5 2.5 3.1e-47 160.2 1.8 1.1 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_6 PF01441.14 EAU90959.1 - 0.0042 16.9 0.5 0.0055 16.5 0.4 1.1 1 0 0 1 1 1 1 Lipoprotein DUF3384 PF11864.3 EAU90959.1 - 0.033 12.6 0.3 0.046 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Kinetochor_Ybp2 PF08568.5 EAU90959.1 - 0.1 10.8 0.4 0.13 10.4 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin F-box-like PF12937.2 EAU90960.2 - 6.9e-06 25.6 1.3 1e-05 25.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU90960.2 - 0.026 14.1 0.0 0.075 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EAU90961.2 - 1.7e-07 30.8 0.2 4.6e-07 29.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU90961.2 - 0.00063 19.3 0.4 0.0038 16.8 0.3 2.3 1 1 0 1 1 1 1 F-box domain Amidohydro_2 PF04909.9 EAU90963.1 - 1.2e-27 97.1 0.1 1.6e-27 96.7 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase FKBP_C PF00254.23 EAU90964.1 - 1e-30 105.5 0.0 1.3e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase F-box-like PF12937.2 EAU90965.1 - 1e-05 25.1 0.3 2.3e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU90966.2 - 8.7e-05 22.1 0.2 0.00063 19.4 0.1 2.6 2 0 0 2 2 2 1 F-box-like WD40 PF00400.27 EAU90967.1 - 0.35 10.8 10.5 29 4.7 0.1 5.0 5 0 0 5 5 5 0 WD domain, G-beta repeat PSCyt3 PF07627.6 EAU90968.1 - 0.13 12.1 2.5 0.23 11.3 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) Hex_IIIa PF02455.11 EAU90968.1 - 0.94 8.0 14.3 1.2 7.7 9.9 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF4407 PF14362.1 EAU90968.1 - 1 8.2 17.2 1.3 7.9 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ResIII PF04851.10 EAU90969.2 - 0.0064 16.3 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EAU90969.2 - 0.064 12.1 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 EAU90969.2 - 0.11 11.9 0.0 0.33 10.3 0.0 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family Mg_trans_NIPA PF05653.9 EAU90972.1 - 2.6e-82 276.1 28.0 3.4e-82 275.8 19.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EAU90972.1 - 2.8e-07 30.6 9.4 2.8e-07 30.6 6.5 3.6 3 1 1 4 4 4 1 EamA-like transporter family EmrE PF13536.1 EAU90972.1 - 1.6e-06 28.2 8.3 1.6e-06 28.2 5.8 3.4 2 2 1 3 3 3 1 Multidrug resistance efflux transporter Oxysterol_BP PF01237.13 EAU90972.1 - 0.088 11.2 6.9 0.13 10.6 4.8 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Arf PF00025.16 EAU90973.1 - 5.2e-29 100.6 0.0 8.7e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EAU90973.1 - 2.3e-10 39.9 0.0 4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EAU90973.1 - 3.5e-06 27.5 0.0 6.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EAU90973.1 - 9.6e-06 25.0 0.0 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EAU90973.1 - 3.7e-05 22.9 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Cytochrom_C1 PF02167.10 EAU90973.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family AAA_14 PF13173.1 EAU90973.1 - 0.079 12.8 0.0 0.93 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain PHD PF00628.24 EAU90975.2 - 0.0094 15.6 6.1 0.02 14.5 4.2 1.6 1 0 0 1 1 1 1 PHD-finger Nucleoplasmin PF03066.10 EAU90977.2 - 0.0034 16.8 2.0 0.038 13.5 0.8 2.5 2 0 0 2 2 2 1 Nucleoplasmin Imm18 PF15566.1 EAU90977.2 - 0.0043 16.3 0.1 0.012 14.9 0.1 1.7 1 0 0 1 1 1 1 Immunity protein 18 Sigma70_ner PF04546.8 EAU90977.2 - 0.44 10.1 2.7 0.43 10.1 0.4 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Nucleo_P87 PF07267.6 EAU90977.2 - 1.2 7.7 4.7 1.9 7.0 3.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MBOAT_2 PF13813.1 EAU90980.1 - 2.6e-09 37.0 0.1 2.6e-09 37.0 0.1 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.1 EAU90981.2 - 2e-23 82.2 0.7 2e-23 82.2 0.5 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Glyco_tranf_2_3 PF13641.1 EAU90982.2 - 2.5e-23 83.0 0.0 3.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EAU90982.2 - 1.4e-08 34.6 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAU90982.2 - 2.5e-08 33.4 0.0 7.7e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EAU90982.2 - 7.1e-06 25.8 4.1 1.2e-05 25.0 2.8 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 EAU90982.2 - 0.0013 17.2 0.4 0.0084 14.5 0.3 1.8 1 1 0 1 1 1 1 Chitin synthase APH PF01636.18 EAU90983.2 - 3.2e-08 33.5 0.1 4.8e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU90983.2 - 5.8e-08 32.5 0.0 9.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Peptidase_M24 PF00557.19 EAU90984.2 - 1.1e-29 103.4 0.7 3.9e-18 65.7 0.0 2.2 1 1 1 2 2 2 2 Metallopeptidase family M24 Creatinase_N PF01321.13 EAU90984.2 - 2.4e-21 76.6 0.1 6.8e-20 71.9 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain DXPR_C PF13288.1 EAU90985.2 - 0.13 12.2 0.0 0.8 9.7 0.0 2.0 2 0 0 2 2 2 0 DXP reductoisomerase C-terminal domain F-box-like PF12937.2 EAU90986.1 - 0.0032 17.1 0.1 0.0032 17.1 0.1 2.8 4 0 0 4 4 4 1 F-box-like MBOAT_2 PF13813.1 EAU90987.2 - 1.2e-23 83.0 3.4 2.8e-23 81.7 0.3 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RCC1 PF00415.13 EAU90988.1 - 9.7e-48 160.1 18.7 2.1e-09 37.4 0.4 8.1 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAU90988.1 - 1.5e-34 116.8 30.8 2.7e-07 29.9 0.7 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat DUF2413 PF10310.4 EAU90988.1 - 8.1 5.1 9.2 11 4.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Baculo_PEP_C PF04513.7 EAU90989.2 - 2 8.2 8.7 0.32 10.8 0.4 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EAU90989.2 - 2.3 8.5 7.2 32 4.8 0.0 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Peptidase_S8 PF00082.17 EAU90992.2 - 4.9e-52 176.8 1.2 6.8e-52 176.3 0.9 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EAU90992.2 - 6.1e-29 99.6 0.3 1.2e-28 98.6 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain ORC6 PF05460.8 EAU90992.2 - 0.0018 17.4 0.4 0.0026 16.9 0.3 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DIOX_N PF14226.1 EAU90993.1 - 6.9e-25 87.8 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAU90993.1 - 6.5e-19 68.0 0.0 1.1e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec2p PF06428.6 EAU90994.2 - 1.2e-08 34.7 17.2 1.2e-08 34.7 11.9 2.8 2 2 1 3 3 3 1 GDP/GTP exchange factor Sec2p HAUS6_N PF14661.1 EAU90994.2 - 0.049 12.9 6.5 0.12 11.6 4.5 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Myosin_tail_1 PF01576.14 EAU90994.2 - 0.13 9.9 27.9 0.012 13.3 11.7 2.1 2 0 0 2 2 2 0 Myosin tail Exonuc_VII_L PF02601.10 EAU90994.2 - 0.16 11.1 10.0 0.013 14.6 2.5 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4140 PF13600.1 EAU90994.2 - 2.5 8.5 17.8 0.25 11.8 0.4 3.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Lipase_GDSL PF00657.17 EAU90995.1 - 9e-14 51.8 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAU90995.1 - 1.9e-13 50.9 0.2 2.5e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4349 PF14257.1 EAU90997.1 - 1.6 7.9 5.7 0.23 10.6 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) F-box-like_2 PF13013.1 EAU90998.2 - 3.2e-06 26.8 0.4 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like domain PIH1 PF08190.7 EAU91001.1 - 3.2 7.0 11.2 4.7 6.5 7.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Sensor PF13796.1 EAU91004.2 - 3.7e-07 29.9 12.9 3.7e-07 29.9 8.9 3.0 2 1 1 3 3 3 2 Putative sensor BCS1_N PF08740.6 EAU91005.2 - 4.7e-18 65.4 4.4 4.7e-18 65.4 3.1 2.2 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EAU91005.2 - 2.9e-15 56.6 0.0 1.3e-06 28.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EAU91005.2 - 0.00014 21.9 1.3 0.00021 21.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EAU91005.2 - 0.0086 16.8 0.0 0.0086 16.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EAU91005.2 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAU91005.2 - 0.026 14.3 0.3 0.026 14.3 0.2 2.9 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EAU91005.2 - 0.027 14.2 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU91005.2 - 0.1 12.7 1.0 0.39 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EAU91005.2 - 0.45 10.8 5.5 0.77 10.0 0.0 2.7 2 0 0 2 2 2 0 ABC transporter adh_short_C2 PF13561.1 EAU91006.2 - 9.6e-26 91.0 0.0 1.2e-25 90.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU91006.2 - 1.7e-20 73.6 3.3 3e-20 72.7 2.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU91006.2 - 0.00041 20.0 0.2 0.0011 18.6 0.1 1.7 1 1 0 1 1 1 1 KR domain GST_N_3 PF13417.1 EAU91007.1 - 9.5e-06 25.7 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU91007.1 - 2.6e-05 24.1 0.0 5.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF1049 PF06305.6 EAU91009.2 - 0.84 9.1 5.1 0.77 9.2 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) R3H PF01424.17 EAU91010.2 - 1.6e-11 43.6 0.0 4.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EAU91010.2 - 6.1e-06 25.9 1.3 2.1e-05 24.1 0.9 2.0 1 0 0 1 1 1 1 G-patch domain DBR1 PF05011.8 EAU91012.1 - 3e-28 98.5 0.2 9.4e-20 70.9 0.0 2.9 2 1 0 2 2 2 2 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EAU91012.1 - 6.3e-09 35.5 0.7 9.3e-09 34.9 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU91012.1 - 0.00043 20.1 0.0 0.00072 19.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4199 PF13858.1 EAU91013.2 - 7.2 6.4 17.3 0.07 13.0 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) CD99L2 PF12301.3 EAU91018.2 - 0.0083 15.8 0.4 0.013 15.2 0.3 1.2 1 0 0 1 1 1 1 CD99 antigen like protein 2 MtaB PF12176.3 EAU91018.2 - 0.07 11.5 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit BAG PF02179.11 EAU91021.1 - 1.7e-13 50.4 0.4 2.3e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EAU91021.1 - 2.3e-06 26.9 0.0 4.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EAU91021.1 - 0.097 12.9 0.0 1.9 8.8 0.0 2.5 1 1 0 1 1 1 0 Ubiquitin-like domain zf-TRAF PF02176.13 EAU91022.2 - 1.4e-06 28.5 2.1 1.4e-06 28.5 1.4 2.0 2 0 0 2 2 2 1 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EAU91022.2 - 2.5e-05 24.1 0.4 2.5e-05 24.1 0.3 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EAU91022.2 - 0.00065 19.1 0.5 0.0018 17.7 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EAU91022.2 - 0.0007 19.3 0.8 0.0007 19.3 0.6 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EAU91022.2 - 0.00091 18.8 0.7 0.00091 18.8 0.5 2.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU91022.2 - 0.0026 17.4 0.1 0.0059 16.2 0.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EAU91022.2 - 0.005 16.5 1.0 0.005 16.5 0.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Sina PF03145.11 EAU91022.2 - 0.017 14.7 2.4 0.028 14.0 1.6 1.3 1 0 0 1 1 1 0 Seven in absentia protein family zf-C3HC4_4 PF15227.1 EAU91022.2 - 0.019 14.8 0.6 0.019 14.8 0.4 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DEAD PF00270.24 EAU91023.2 - 5e-35 120.4 0.0 8.9e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EAU91023.2 - 1.3e-18 66.2 0.3 2.4e-18 65.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EAU91023.2 - 1.8e-16 59.7 0.0 3.8e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nop14 PF04147.7 EAU91023.2 - 0.022 12.7 2.3 0.036 12.0 1.6 1.2 1 0 0 1 1 1 0 Nop14-like family ResIII PF04851.10 EAU91023.2 - 0.027 14.2 0.0 0.027 14.2 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CDC45 PF02724.9 EAU91023.2 - 0.03 12.3 0.0 0.053 11.5 0.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EAU91023.2 - 1.5 8.3 9.4 4.6 6.7 6.5 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EAU91023.2 - 1.7 8.1 9.5 4.3 6.8 6.6 1.6 1 0 0 1 1 1 0 Nucleoplasmin MOZ_SAS PF01853.13 EAU91024.2 - 2.9e-82 274.4 0.3 4.1e-82 273.9 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EAU91024.2 - 6.9e-19 67.3 0.0 1.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_Mga PF08280.6 EAU91024.2 - 0.0028 17.3 0.1 0.006 16.3 0.1 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_1 PF00583.19 EAU91024.2 - 0.039 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2 PF00096.21 EAU91024.2 - 2 8.9 5.6 0.89 10.0 1.9 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_pol_phi PF04931.8 EAU91025.2 - 0.11 10.2 0.0 0.15 9.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi LAG1-DNAbind PF09271.6 EAU91026.1 - 1.1e-34 119.8 0.1 2e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EAU91026.1 - 8.6e-23 80.8 0.0 1.5e-20 73.5 0.0 2.9 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4200 PF13863.1 EAU91028.2 - 0.11 12.4 3.8 0.17 11.8 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) bZIP_1 PF00170.16 EAU91028.2 - 1.2 9.1 10.0 2.2 8.2 6.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 EAU91028.2 - 4.3 7.2 9.8 9.5 6.1 6.8 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Put_Phosphatase PF06888.7 EAU91032.1 - 1.1e-51 175.2 0.0 1.2e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.2 EAU91032.1 - 0.00047 20.3 0.0 0.00064 19.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU91032.1 - 0.0023 18.3 0.0 0.0034 17.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EAU91032.1 - 0.0071 16.5 0.1 0.017 15.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 EAU91032.1 - 0.019 13.9 0.0 0.069 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Hydrolase_3 PF08282.7 EAU91032.1 - 0.07 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase BSD PF03909.12 EAU91033.1 - 1.5e-22 79.0 0.2 2.2e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EAU91033.1 - 6.3e-11 41.7 0.0 1.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Ribosomal_L19e PF01280.15 EAU91034.2 - 0.0063 16.2 7.9 0.0089 15.8 5.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L19e DUF4055 PF13264.1 EAU91034.2 - 1.1 9.3 3.8 2.1 8.4 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Ribosomal_S9 PF00380.14 EAU91037.2 - 2.3e-32 111.7 0.0 4.2e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 mRNA_triPase PF02940.10 EAU91037.2 - 0.025 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain BRE1 PF08647.6 EAU91038.2 - 5e-17 61.6 9.5 5e-17 61.6 6.6 7.3 5 3 3 8 8 8 1 BRE1 E3 ubiquitin ligase DUF1664 PF07889.7 EAU91038.2 - 0.0014 18.4 0.3 0.0014 18.4 0.2 5.5 4 2 2 7 7 7 1 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 EAU91038.2 - 0.0046 16.1 0.6 0.0046 16.1 0.4 4.3 3 1 1 4 4 4 2 Reovirus sigma C capsid protein GED PF02212.13 EAU91038.2 - 3.7 7.5 13.6 0.024 14.5 1.4 3.4 3 0 0 3 3 3 0 Dynamin GTPase effector domain Allantoicase PF03561.10 EAU91039.2 - 2e-92 306.5 0.0 3.6e-46 156.3 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 EAU91039.2 - 1.2e-41 141.8 0.0 1.7e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase F5_F8_type_C PF00754.20 EAU91039.2 - 0.0002 21.2 0.1 0.22 11.3 0.0 2.4 2 0 0 2 2 2 2 F5/8 type C domain Zn_clus PF00172.13 EAU91042.1 - 0.0011 18.8 12.4 0.002 18.0 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EAU91042.1 - 0.0033 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EAU91042.1 - 0.2 12.0 0.0 0.38 11.1 0.0 1.4 1 0 0 1 1 1 0 PAS domain PRA1 PF03208.14 EAU91043.2 - 5.6e-39 132.9 1.2 6.6e-39 132.7 0.9 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF3040 PF11239.3 EAU91043.2 - 0.54 10.3 3.9 4.1 7.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) YrhK PF14145.1 EAU91043.2 - 4.9 6.8 8.7 22 4.7 6.0 2.2 1 1 0 1 1 1 0 YrhK-like protein zf-DHHC PF01529.15 EAU91043.2 - 6.9 6.0 5.8 13 5.1 4.0 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase F-box-like PF12937.2 EAU91045.2 - 0.014 15.0 0.2 0.069 12.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like Rad9 PF04139.8 EAU91046.2 - 6.5e-16 58.2 0.1 9.1e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Rad9 DUF663 PF04950.7 EAU91047.2 - 8.6e-101 336.8 0.0 1.5e-100 336.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EAU91047.2 - 5.7e-19 67.4 0.0 2.6e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 AARP2CN (NUC121) domain CBM_5_12 PF02839.9 EAU91047.2 - 0.14 11.7 0.2 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain Voltage_CLC PF00654.15 EAU91049.2 - 8.7e-89 297.9 37.5 9.6e-89 297.8 25.1 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EAU91049.2 - 5.8e-15 54.8 0.5 6.5e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Septin PF00735.13 EAU91050.1 - 2.4e-107 358.1 0.5 3.1e-107 357.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EAU91050.1 - 0.0002 21.2 0.0 0.00045 20.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU91050.1 - 0.0011 18.8 3.1 0.42 10.4 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 EAU91050.1 - 0.0015 17.6 0.0 0.003 16.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_17 PF13207.1 EAU91050.1 - 0.0017 19.1 1.7 0.013 16.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EAU91050.1 - 0.0049 16.3 0.1 0.098 12.0 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EAU91050.1 - 0.0052 15.9 0.3 0.028 13.6 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EAU91050.1 - 0.016 14.6 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EAU91050.1 - 0.032 14.7 0.1 0.092 13.2 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein IIGP PF05049.8 EAU91050.1 - 0.051 12.3 0.1 0.12 11.1 0.1 1.6 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 EAU91050.1 - 0.13 12.3 0.2 0.72 9.9 0.0 2.3 2 2 0 2 2 2 0 AAA domain MobB PF03205.9 EAU91050.1 - 0.15 11.7 0.0 0.4 10.3 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3653 PF12375.3 EAU91050.1 - 0.38 10.9 2.6 0.55 10.4 0.8 2.1 2 0 0 2 2 2 0 Phage protein adh_short PF00106.20 EAU91051.1 - 1.7e-21 76.8 2.2 5.2e-21 75.2 1.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU91051.1 - 3.1e-06 26.9 0.9 3.4e-05 23.5 0.6 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EAU91051.1 - 3.5e-06 26.9 0.0 8e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1097 PF06496.6 EAU91053.2 - 0.068 12.9 3.7 0.094 12.5 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1097) DASH_Dad2 PF08654.5 EAU91054.1 - 0.14 12.1 1.6 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad2 Pro_isomerase PF00160.16 EAU91055.2 - 1.4e-47 161.7 0.5 2.1e-47 161.2 0.3 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DPBB_1 PF03330.13 EAU91056.1 - 1.2e-05 25.1 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Acetyltransf_7 PF13508.1 EAU91057.2 - 7.9e-09 35.5 0.4 1.5e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU91057.2 - 6.4e-06 26.1 0.1 1.4e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Bromodomain PF00439.20 EAU91057.2 - 7.9e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.1 EAU91057.2 - 0.0034 17.5 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAU91057.2 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein 2-Hacid_dh_C PF02826.14 EAU91058.2 - 1.8e-46 157.5 0.0 2.6e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAU91058.2 - 8.8e-19 67.2 0.0 1.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EAU91058.2 - 5.6e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase EXS PF03124.9 EAU91059.2 - 3.2e-87 292.7 4.4 3.7e-87 292.5 3.0 1.0 1 0 0 1 1 1 1 EXS family PalH PF08733.5 EAU91059.2 - 0.076 11.8 0.4 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 PalH/RIM21 zf-C2H2_jaz PF12171.3 EAU91060.2 - 1.6e-07 31.2 0.2 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU91060.2 - 1.6e-05 24.9 0.3 2.5e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EAU91060.2 - 0.00086 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF1777 PF08648.7 EAU91060.2 - 0.0033 17.1 5.8 0.0033 17.1 4.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) DUF572 PF04502.8 EAU91060.2 - 0.016 14.4 10.6 0.41 9.8 2.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) zf-C2H2 PF00096.21 EAU91060.2 - 0.047 14.0 0.4 0.079 13.3 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EAU91060.2 - 0.12 12.3 0.2 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3451 PF11933.3 EAU91060.2 - 4.2 7.1 8.9 0.32 10.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3451) Peptidase_S49_N PF08496.5 EAU91060.2 - 5.2 6.8 11.7 1.7 8.4 1.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Med19 PF10278.4 EAU91060.2 - 8.7 5.9 14.7 3.2 7.3 1.8 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 tRNA-synt_1 PF00133.17 EAU91061.2 - 2e-223 742.7 0.0 6.7e-223 741.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EAU91061.2 - 1.9e-27 95.9 0.3 3.4e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EAU91061.2 - 1.1e-17 63.8 0.3 2.1e-07 29.9 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EAU91061.2 - 0.017 14.2 0.0 0.063 12.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Arf PF00025.16 EAU91062.2 - 1.6e-34 118.6 0.0 2.2e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EAU91062.2 - 4.3e-13 48.7 0.0 3.3e-08 32.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EAU91062.2 - 6.3e-09 36.3 0.0 9.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EAU91062.2 - 7.8e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EAU91062.2 - 3e-06 26.5 0.0 5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EAU91062.2 - 3.7e-06 26.2 0.0 6.9e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EAU91062.2 - 4.6e-06 26.5 0.0 6.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EAU91062.2 - 0.0036 17.6 0.1 0.0066 16.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EAU91062.2 - 0.0047 17.0 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EAU91062.2 - 0.0054 16.2 0.0 0.14 11.6 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EAU91062.2 - 0.0075 15.7 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 EAU91062.2 - 0.013 15.8 0.4 0.017 15.4 0.3 1.3 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EAU91062.2 - 0.017 14.5 0.2 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 EAU91062.2 - 0.02 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EAU91062.2 - 0.047 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EAU91062.2 - 0.049 13.3 0.3 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EAU91062.2 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EAU91062.2 - 0.059 13.2 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU91062.2 - 0.063 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EAU91062.2 - 0.077 13.8 1.5 0.15 12.8 1.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EAU91062.2 - 0.087 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 EAU91062.2 - 0.096 12.6 0.1 0.1 12.5 0.1 1.3 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EAU91062.2 - 0.099 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MobB PF03205.9 EAU91062.2 - 0.17 11.6 0.4 0.32 10.7 0.1 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_C PF00137.16 EAU91063.2 - 4.2e-25 87.4 23.8 5.7e-16 58.1 5.8 2.8 4 0 0 4 4 4 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 EAU91063.2 - 0.052 13.7 2.3 1.2 9.3 0.5 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Oxidored_q2 PF00420.19 EAU91063.2 - 3.9 7.1 7.1 1.1 8.9 1.6 2.5 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CUE PF02845.11 EAU91064.2 - 3.5e-08 32.7 0.0 5.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain SET PF00856.23 EAU91065.1 - 1.9e-14 54.2 0.1 4.4e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 EAU91065.1 - 1.9e-09 37.5 0.0 6.5e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding CRS1_YhbY PF01985.16 EAU91065.1 - 0.097 12.6 0.1 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain DAP PF15228.1 EAU91065.1 - 0.75 10.5 12.1 0.071 13.8 0.7 3.5 3 1 0 3 3 3 0 Death-associated protein DNA_pol_phi PF04931.8 EAU91065.1 - 5.5 4.6 20.4 8.3 4.0 14.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Metallophos PF00149.23 EAU91066.2 - 6.1e-29 100.8 0.2 2.2e-28 99.0 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCCH PF00642.19 EAU91068.1 - 8.1e-09 34.9 2.5 1.8e-08 33.8 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EAU91068.1 - 2.4e-08 33.4 4.3 4.1e-08 32.7 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU91068.1 - 1.5e-07 31.3 9.9 2.5e-07 30.5 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU91068.1 - 1.6e-07 30.9 7.7 2.7e-07 30.1 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EAU91068.1 - 2.4e-05 24.0 6.8 4e-05 23.3 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EAU91068.1 - 3.7e-05 23.2 9.0 7.3e-05 22.3 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EAU91068.1 - 0.00096 18.8 5.3 0.0032 17.1 3.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAU91068.1 - 0.0022 17.8 7.2 0.005 16.6 5.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EAU91068.1 - 0.12 11.8 1.9 0.24 10.9 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_L34e PF01199.13 EAU91068.1 - 1 9.6 4.1 0.57 10.4 0.5 2.2 2 0 0 2 2 2 0 Ribosomal protein L34e zf-RanBP PF00641.13 EAU91068.1 - 2.3 7.4 7.8 0.05 12.7 0.8 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-rbx1 PF12678.2 EAU91068.1 - 4.3 7.5 6.2 16 5.7 4.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger bZIP_2 PF07716.10 EAU91069.1 - 3.6e-10 39.5 12.7 3.6e-10 39.5 8.8 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 EAU91069.1 - 0.00032 20.6 13.4 0.00032 20.6 9.3 2.8 2 1 0 2 2 2 1 bZIP transcription factor PAT1 PF09770.4 EAU91069.1 - 0.0039 15.5 25.7 0.0052 15.0 17.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 MAD PF05557.8 EAU91069.1 - 0.011 13.9 0.5 0.018 13.1 0.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein XhlA PF10779.4 EAU91069.1 - 0.029 14.2 0.1 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA CASP_C PF08172.7 EAU91069.1 - 0.067 12.2 4.6 0.14 11.2 3.2 1.4 1 0 0 1 1 1 0 CASP C terminal SR-25 PF10500.4 EAU91069.1 - 0.21 11.0 12.3 0.033 13.6 5.8 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein bZIP_Maf PF03131.12 EAU91069.1 - 7.8 6.8 11.2 0.43 10.9 2.5 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor LysM PF01476.15 EAU91071.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 LysM domain GLTP PF08718.6 EAU91073.1 - 2e-39 135.0 0.0 3.4e-39 134.2 0.0 1.4 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) tRNA-synt_1e PF01406.14 EAU91074.2 - 8.8e-119 396.0 0.0 1.3e-118 395.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EAU91074.2 - 2e-08 33.2 0.3 2e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EAU91074.2 - 6.2e-08 31.1 0.0 7.4e-07 27.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 EAU91074.2 - 0.0016 17.2 0.1 0.32 9.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) Gti1_Pac2 PF09729.4 EAU91075.2 - 2.4e-26 92.5 7.6 4.7e-22 78.6 0.9 2.9 2 1 1 3 3 3 2 Gti1/Pac2 family Corona_nucleoca PF00937.13 EAU91075.2 - 0.077 11.9 2.1 0.1 11.5 1.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Gti1_Pac2 PF09729.4 EAU91077.2 - 4.4e-15 55.9 8.1 3.4e-14 53.0 0.0 3.3 2 2 1 3 3 3 2 Gti1/Pac2 family TFIIA PF03153.8 EAU91078.2 - 3.8e-46 158.7 13.8 1.1e-33 117.6 0.8 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit ATP-synt_B PF00430.13 EAU91079.2 - 2.5 7.9 10.0 3.7 7.3 6.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) BRO1 PF03097.13 EAU91080.1 - 4.3e-17 61.9 0.0 6.3e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain PIG-U PF06728.8 EAU91081.2 - 2.4e-108 362.4 29.5 2.8e-108 362.1 20.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U PALP PF00291.20 EAU91082.2 - 1.7e-50 172.0 0.0 5.7e-25 88.1 0.0 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme CoA_binding_2 PF13380.1 EAU91083.1 - 9.9e-29 99.8 0.0 1.2e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EAU91083.1 - 0.019 15.4 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Glyco_hydro_18 PF00704.23 EAU91084.2 - 2.5e-46 158.6 0.0 2e-42 145.9 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 zf-C2H2 PF00096.21 EAU91085.1 - 1.8e-12 46.8 14.3 0.00023 21.2 0.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU91085.1 - 1.1e-08 34.7 14.9 0.013 15.7 0.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU91085.1 - 1e-05 25.5 9.6 0.00017 21.7 0.3 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EAU91085.1 - 0.00041 20.4 6.2 0.029 14.5 0.6 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAU91085.1 - 0.00048 20.1 9.0 0.11 12.6 0.6 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAU91085.1 - 0.067 13.1 11.0 0.73 9.8 0.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger BSP_II PF05432.6 EAU91085.1 - 0.94 8.7 18.4 0.083 12.1 8.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Zn_Tnp_IS1595 PF12760.2 EAU91085.1 - 1.3 8.8 5.8 3 7.7 4.0 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain C1_4 PF07975.7 EAU91085.1 - 2.2 8.3 5.0 2.2 8.3 1.4 2.3 1 1 0 1 1 1 0 TFIIH C1-like domain Mito_carr PF00153.22 EAU91086.1 - 6.2e-66 218.1 5.0 9.3e-23 79.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 EAU91087.2 - 1.1e-05 25.0 0.3 5.2e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EAU91087.2 - 0.053 13.1 0.3 8 6.2 0.0 2.6 2 0 0 2 2 2 0 F-box domain DUF3844 PF12955.2 EAU91088.1 - 1.7e-33 114.7 4.1 2.5e-33 114.2 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Sec3-PIP2_bind PF15277.1 EAU91088.1 - 0.065 13.1 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH EGF PF00008.22 EAU91088.1 - 2.2 8.3 7.1 3.7 7.5 4.9 1.3 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.8 EAU91088.1 - 8.2 6.6 10.5 20 5.4 7.3 1.6 1 0 0 1 1 1 0 EGF-like domain Gti1_Pac2 PF09729.4 EAU91089.2 - 4e-26 91.8 0.1 3.3e-22 79.1 0.0 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family Glutaredoxin PF00462.19 EAU91091.1 - 0.0018 18.2 0.0 0.0073 16.2 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin O-FucT PF10250.4 EAU91092.2 - 3.1e-09 36.4 0.0 0.0033 16.6 0.0 2.8 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.11 EAU91092.2 - 0.094 11.6 0.0 0.27 10.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 11 IGPD PF00475.13 EAU91092.2 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase O-FucT PF10250.4 EAU91093.2 - 8.3e-06 25.1 0.0 0.077 12.0 0.0 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.11 EAU91093.2 - 0.079 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 11 CMAS PF02353.15 EAU91094.2 - 2.7e-26 92.2 0.0 3.3e-25 88.6 0.0 2.2 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EAU91094.2 - 2.6e-12 46.5 0.0 4.4e-12 45.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU91094.2 - 3.1e-09 37.4 0.0 5.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU91094.2 - 6.2e-08 33.0 0.0 3.1e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU91094.2 - 1.2e-06 28.0 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EAU91094.2 - 1.9e-06 28.2 0.0 6.3e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU91094.2 - 4.5e-05 23.7 0.0 9.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAU91094.2 - 8.3e-05 21.7 0.0 0.00049 19.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.9 EAU91094.2 - 0.00012 21.3 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.6 EAU91094.2 - 0.00048 18.9 0.0 0.00072 18.3 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_23 PF13489.1 EAU91094.2 - 0.00075 19.2 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain GidB PF02527.10 EAU91094.2 - 0.0039 16.3 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NodS PF05401.6 EAU91094.2 - 0.04 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EAU91094.2 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EAU91094.2 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EAU91094.2 - 0.07 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EAU91094.2 - 0.13 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bax1-I PF01027.15 EAU91095.1 - 7.8e-49 166.0 25.2 9.1e-49 165.8 17.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4293 PF14126.1 EAU91095.1 - 4.3 7.2 8.2 28 4.5 5.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Sigma70_ner PF04546.8 EAU91096.2 - 0.11 12.1 1.4 0.21 11.1 1.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region HAD_2 PF13419.1 EAU91097.1 - 3e-19 69.8 0.0 4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU91097.1 - 6.4e-10 39.7 0.0 1e-09 39.1 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU91097.1 - 4.2e-07 29.5 0.0 1.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EAU91097.1 - 0.00081 19.2 0.0 0.067 13.0 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU91097.1 - 0.0035 17.5 0.0 0.0058 16.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EAU91097.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Glutaredoxin PF00462.19 EAU91098.2 - 8.8e-14 51.2 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EAU91098.2 - 0.0024 18.0 0.0 0.0048 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Esterase_phd PF10503.4 EAU91099.1 - 9.2e-22 77.3 0.4 1.2e-21 76.9 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EAU91099.1 - 4.5e-14 51.7 12.9 4.5e-14 51.7 8.9 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EAU91099.1 - 8.2e-09 34.9 0.2 1.3e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAU91099.1 - 7.8e-05 22.6 0.7 0.00015 21.7 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU91099.1 - 0.00065 19.4 0.1 0.00089 19.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU91099.1 - 0.00072 19.1 0.2 0.0018 17.8 0.0 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EAU91099.1 - 0.01 15.2 0.9 0.025 13.9 0.6 1.7 1 1 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 EAU91099.1 - 0.034 13.7 0.2 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EAU91099.1 - 0.05 13.0 0.1 0.096 12.1 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Toxin_7 PF05980.7 EAU91099.1 - 4.7 7.3 11.2 11 6.1 7.8 1.7 1 0 0 1 1 1 0 Toxin 7 TPR_2 PF07719.12 EAU91100.2 - 7.1e-31 103.6 32.7 0.0028 17.4 0.0 13.7 13 1 1 14 14 14 8 Tetratricopeptide repeat TPR_12 PF13424.1 EAU91100.2 - 1.6e-27 95.2 36.6 0.00082 19.2 0.0 11.0 8 3 2 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 EAU91100.2 - 1.9e-27 94.6 40.5 1.1e-07 31.3 0.0 11.0 7 4 6 13 13 13 8 TPR repeat TPR_19 PF14559.1 EAU91100.2 - 1.4e-25 89.4 33.3 0.00078 19.7 0.0 11.4 9 1 2 11 11 11 9 Tetratricopeptide repeat TPR_1 PF00515.23 EAU91100.2 - 5.7e-22 76.3 37.3 7.9e-05 22.0 0.0 13.3 15 1 1 16 16 15 6 Tetratricopeptide repeat TPR_8 PF13181.1 EAU91100.2 - 3.6e-19 67.0 17.0 0.0075 15.9 0.0 10.8 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_14 PF13428.1 EAU91100.2 - 5.8e-19 66.8 46.6 0.00094 19.6 0.0 14.6 11 4 5 16 16 14 6 Tetratricopeptide repeat TPR_6 PF13174.1 EAU91100.2 - 1.3e-17 62.9 27.6 0.00098 19.4 0.0 14.0 13 1 1 14 14 14 4 Tetratricopeptide repeat TPR_16 PF13432.1 EAU91100.2 - 2.3e-16 59.9 45.7 6.1e-06 26.7 0.0 11.2 11 1 2 13 13 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 EAU91100.2 - 1.1e-12 46.6 24.1 0.15 11.9 0.0 11.1 11 1 1 12 12 12 5 Tetratricopeptide repeat Apc3 PF12895.2 EAU91100.2 - 9.3e-10 38.5 23.7 0.11 12.7 0.0 6.6 6 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EAU91100.2 - 1.1e-06 28.3 16.5 5.5 7.4 0.0 11.5 12 1 2 14 14 14 1 Tetratricopeptide repeat TPR_4 PF07721.9 EAU91100.2 - 0.00057 20.0 12.6 3 8.5 2.6 7.1 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR_2 PF13041.1 EAU91100.2 - 0.12 12.4 1.3 12 5.9 0.0 3.6 3 0 0 3 3 2 0 PPR repeat family TPR_10 PF13374.1 EAU91100.2 - 0.49 10.3 0.0 0.49 10.3 0.0 10.7 14 0 0 14 14 10 0 Tetratricopeptide repeat Ribosomal_S2 PF00318.15 EAU91101.1 - 4.6e-47 159.9 0.1 1.7e-23 82.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 SGL PF08450.7 EAU91102.2 - 3.1e-08 33.3 0.1 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EAU91102.2 - 1.8e-05 24.6 0.0 5.7e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Arylesterase Peptidase_C1_2 PF03051.10 EAU91103.1 - 5.1e-153 509.6 0.0 6.1e-153 509.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EAU91103.1 - 2.5e-07 30.8 0.0 0.022 14.6 0.0 2.6 3 0 0 3 3 3 2 Papain family cysteine protease TauD PF02668.11 EAU91105.2 - 6.7e-57 193.0 0.1 8.1e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DnaJ PF00226.26 EAU91107.2 - 5.8e-15 54.7 0.2 1e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain ZF-HD_dimer PF04770.7 EAU91107.2 - 0.74 9.9 3.5 2.9 8.0 1.8 2.2 2 0 0 2 2 2 0 ZF-HD protein dimerisation region HlyIII PF03006.15 EAU91108.1 - 3.1e-39 134.6 24.8 1.4e-38 132.5 17.2 1.9 1 1 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.13 EAU91108.1 - 0.0023 17.5 3.8 0.044 13.2 2.8 2.7 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain Cupin_4 PF08007.7 EAU91108.1 - 0.039 13.1 0.2 2.2 7.4 0.1 2.2 1 1 1 2 2 2 0 Cupin superfamily protein DUF883 PF05957.8 EAU91108.1 - 0.11 12.8 0.3 5.1 7.5 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) TRP PF06011.7 EAU91109.2 - 6.2e-70 235.9 12.5 8.4e-70 235.5 8.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EAU91109.2 - 2.6e-24 85.8 0.1 4.9e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 ML-like domain OSCP PF00213.13 EAU91110.1 - 7.8e-42 143.0 2.5 9e-42 142.8 1.8 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Peptidase_S46 PF10459.4 EAU91110.1 - 0.00051 18.5 0.1 0.00056 18.4 0.1 1.0 1 0 0 1 1 1 1 Peptidase S46 DUF3035 PF11233.3 EAU91110.1 - 0.032 14.2 0.3 0.048 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) ICMT PF04140.9 EAU91111.1 - 9.1e-14 51.4 0.0 7.6e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EAU91111.1 - 7.9e-11 42.0 0.2 7.8e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EAU91111.1 - 1.3e-05 23.9 0.0 2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CopD PF05425.8 EAU91111.1 - 0.0092 16.1 0.4 3.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Copper resistance protein D Abhydrolase_2 PF02230.11 EAU91112.2 - 2.6e-34 118.5 0.0 1.2e-32 113.0 0.0 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EAU91112.2 - 1.5e-07 31.2 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU91112.2 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EAU91112.2 - 0.02 14.6 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EAU91112.2 - 0.03 13.9 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.8 EAU91112.2 - 0.14 11.5 0.0 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Asp PF00026.18 EAU91113.2 - 2e-66 224.4 0.0 2.6e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAU91113.2 - 9.9e-07 28.8 0.3 9.9e-06 25.5 0.2 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EAU91113.2 - 0.0043 17.5 0.1 0.0043 17.5 0.1 2.3 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EAU91113.2 - 0.013 15.0 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal GCC2_GCC3 PF07699.8 EAU91114.1 - 4e-16 58.3 38.3 4.5e-06 26.1 3.8 5.2 2 2 2 4 4 4 4 GCC2 and GCC3 NCD3G PF07562.9 EAU91114.1 - 2.2e-05 24.0 27.3 0.034 13.8 0.7 5.6 4 1 1 5 5 5 4 Nine Cysteines Domain of family 3 GPCR CUE PF02845.11 EAU91115.1 - 0.0011 18.3 0.1 0.0069 15.8 0.1 2.4 2 1 0 2 2 2 1 CUE domain ICA69 PF04629.9 EAU91115.1 - 0.021 14.7 1.3 0.033 14.1 0.1 1.9 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain Glyco_hydro_16 PF00722.16 EAU91116.1 - 1e-17 64.0 0.1 1.7e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DNase_NucA_NucB PF14040.1 EAU91117.2 - 1.1e-08 35.1 0.1 1.8e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB LRR_4 PF12799.2 EAU91118.1 - 0.031 13.9 0.5 10 5.8 0.0 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF4383 PF14325.1 EAU91118.1 - 0.15 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) Methyltransf_31 PF13847.1 EAU91119.2 - 2.3e-14 53.2 0.1 3.5e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAU91119.2 - 5.3e-12 45.4 0.0 8.3e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EAU91119.2 - 8.4e-12 45.6 0.0 1.7e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU91119.2 - 4.2e-10 39.9 0.0 9.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU91119.2 - 2.3e-09 37.3 0.0 5.6e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU91119.2 - 2e-08 33.8 0.0 3.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EAU91119.2 - 3.5e-08 33.3 0.0 7.4e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EAU91119.2 - 6e-08 31.7 0.0 8.4e-08 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 EAU91119.2 - 2.4e-07 30.0 0.0 3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EAU91119.2 - 3.2e-07 30.7 0.0 7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EAU91119.2 - 6e-07 28.8 0.0 8.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EAU91119.2 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EAU91119.2 - 4.9e-05 22.5 0.0 7.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EAU91119.2 - 0.00025 20.5 0.1 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EAU91119.2 - 0.00067 18.8 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EAU91119.2 - 0.0016 18.1 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAU91119.2 - 0.0016 18.4 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EAU91119.2 - 0.0019 17.7 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EAU91119.2 - 0.0027 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EAU91119.2 - 0.0084 16.9 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EAU91119.2 - 0.011 14.9 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Cons_hypoth95 PF03602.10 EAU91119.2 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.12 EAU91119.2 - 0.085 11.8 0.0 0.2 10.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DUF2367 PF10164.4 EAU91120.1 - 8.5e-08 31.9 2.1 1.9e-07 30.8 1.4 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) zf-HIT PF04438.11 EAU91120.1 - 0.088 12.4 1.0 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 HIT zinc finger Methyltransf_16 PF10294.4 EAU91121.1 - 2e-06 27.3 0.0 0.0015 18.0 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase DUF2456 PF10445.4 EAU91124.1 - 0.25 11.2 0.0 0.25 11.2 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2456) Na_Pi_cotrans PF02690.10 EAU91124.1 - 0.43 10.3 7.6 0.48 10.1 3.8 1.9 1 1 1 2 2 2 0 Na+/Pi-cotransporter RseC_MucC PF04246.7 EAU91124.1 - 1.3 8.5 5.6 0.81 9.2 1.9 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC CPSF73-100_C PF11718.3 EAU91125.2 - 2.3e-55 187.3 0.2 3.5e-55 186.6 0.2 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EAU91125.2 - 6.5e-32 110.1 0.0 1.5e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EAU91125.2 - 5.2e-13 49.0 0.3 5.2e-13 49.0 0.2 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EAU91125.2 - 7.3e-11 41.7 0.1 1.5e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EAU91125.2 - 9.2e-09 35.1 2.3 1.4e-08 34.5 0.4 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EAU91125.2 - 1.2e-05 25.0 3.4 2.4e-05 24.0 0.0 3.0 3 1 0 3 3 3 1 Beta-lactamase superfamily domain VPS11_C PF12451.3 EAU91126.1 - 0.31 10.9 3.9 4.4 7.2 2.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal TauD PF02668.11 EAU91128.2 - 9.5e-48 163.0 0.1 1.2e-47 162.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Lum_binding PF00677.12 EAU91128.2 - 0.063 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Lumazine binding domain SUR7 PF06687.7 EAU91129.2 - 1.9e-13 50.4 9.8 1.7e-12 47.3 6.8 2.0 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EAU91129.2 - 0.00043 20.0 8.5 0.00089 18.9 5.7 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF998 PF06197.8 EAU91129.2 - 0.004 16.4 17.2 0.063 12.5 7.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF998) Oxidored_q2 PF00420.19 EAU91129.2 - 0.0044 16.5 3.7 0.044 13.3 1.7 2.3 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PhyH PF05721.8 EAU91131.2 - 1.1e-47 162.8 0.0 1.4e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) BRCT PF00533.21 EAU91132.2 - 0.013 15.6 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Glyco_hydro_63 PF03200.11 EAU91136.1 - 9.7e-05 20.4 13.5 0.0001 20.3 0.6 4.1 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase RhoGAP PF00620.22 EAU91137.2 - 1.2e-28 99.6 0.0 2.2e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Mito_carr PF00153.22 EAU91139.1 - 1e-75 249.5 0.0 1e-26 92.4 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein VSP PF03302.8 EAU91142.2 - 0.006 15.2 0.2 0.0082 14.8 0.1 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mid1 PF12929.2 EAU91143.2 - 1.1e-91 307.7 0.0 1.3e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EAU91143.2 - 0.017 15.4 1.9 0.86 9.9 0.1 2.4 2 0 0 2 2 2 0 Fz domain Lipase_3 PF01764.20 EAU91144.2 - 2.7e-28 98.3 0.1 5.2e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EAU91144.2 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EAU91144.2 - 0.0033 16.7 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF2974 PF11187.3 EAU91144.2 - 0.0089 15.4 0.4 0.017 14.4 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EAU91144.2 - 0.0099 15.7 0.1 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EAU91144.2 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EAU91144.2 - 0.02 14.3 0.1 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF2048 PF09752.4 EAU91144.2 - 0.07 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) SWIRM PF04433.12 EAU91145.2 - 1.2e-16 60.5 0.0 3.4e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EAU91145.2 - 4.4e-10 39.4 0.1 1.1e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAU91145.2 - 0.00022 21.2 0.1 0.00083 19.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EAU91145.2 - 0.0023 17.4 8.8 0.0056 16.2 6.1 1.6 1 1 0 1 1 1 1 Zinc finger, ZZ type Ins_beta PF03488.9 EAU91145.2 - 0.29 10.9 2.8 0.69 9.7 1.9 1.6 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type DUF4235 PF14019.1 EAU91146.1 - 0.078 12.8 0.4 0.46 10.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Collagen_bind_2 PF12904.2 EAU91146.1 - 0.083 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase DUF2157 PF09925.4 EAU91147.2 - 0.00022 20.8 4.8 0.00022 20.8 3.3 2.5 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) DUF4386 PF14329.1 EAU91147.2 - 0.0022 17.4 4.3 0.0022 17.4 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4386) DUF4117 PF13491.1 EAU91147.2 - 0.054 12.9 6.6 0.15 11.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4117) 7tm_7 PF08395.7 EAU91147.2 - 0.055 12.4 1.0 0.19 10.7 0.1 2.1 2 1 0 2 2 2 0 7tm Chemosensory receptor PepSY_TM_2 PF13703.1 EAU91147.2 - 0.16 12.1 8.1 1.3 9.2 3.3 3.4 1 1 2 3 3 3 0 PepSY-associated TM helix DUF1129 PF06570.6 EAU91147.2 - 0.17 11.1 4.3 0.059 12.6 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1772 PF08592.6 EAU91147.2 - 0.23 11.2 6.2 0.2 11.3 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) FA_desaturase PF00487.19 EAU91147.2 - 0.46 9.8 6.9 0.044 13.2 1.5 1.7 2 0 0 2 2 2 0 Fatty acid desaturase TauE PF01925.14 EAU91147.2 - 0.47 9.8 9.4 0.16 11.3 2.4 2.2 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF998 PF06197.8 EAU91147.2 - 1.1 8.5 13.1 0.73 9.1 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF747 PF05346.6 EAU91148.2 - 4.6e-116 387.5 1.4 6e-116 387.1 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family HK PF02110.10 EAU91149.1 - 5e-76 255.1 2.8 1.3e-75 253.8 1.9 1.7 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EAU91149.1 - 7.1e-56 188.1 0.2 7.1e-56 188.1 0.2 2.0 2 1 1 3 3 3 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EAU91149.1 - 6.4e-05 22.2 0.0 0.00022 20.4 0.0 1.9 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase QRPTase_C PF01729.14 EAU91149.1 - 0.002 17.6 0.8 0.064 12.7 0.0 2.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain BTB PF00651.26 EAU91151.1 - 2.6e-05 24.1 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TP6A_N PF04406.9 EAU91152.2 - 1.5e-22 78.9 0.0 3.5e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase F-box-like PF12937.2 EAU91153.1 - 7.5e-05 22.3 0.1 7.5e-05 22.3 0.1 2.7 3 0 0 3 3 3 1 F-box-like RCR PF12273.3 EAU91154.2 - 0.00051 20.6 1.8 0.00075 20.0 0.1 2.1 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Shisa PF13908.1 EAU91154.2 - 0.00072 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1191 PF06697.7 EAU91154.2 - 0.013 14.2 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) FAM176 PF14851.1 EAU91154.2 - 0.016 14.8 0.0 6.9 6.3 0.0 2.8 3 0 0 3 3 3 0 FAM176 family EphA2_TM PF14575.1 EAU91154.2 - 0.055 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EAU91154.2 - 0.11 12.0 0.9 0.18 11.3 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 AAA_16 PF13191.1 EAU91155.1 - 4.7e-10 39.7 0.3 4.7e-10 39.7 0.2 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU91155.1 - 6.4e-10 39.2 0.1 6.4e-10 39.2 0.1 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EAU91155.1 - 1.9e-09 37.3 0.2 4.3e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EAU91155.1 - 5.4e-08 33.1 0.1 1.6e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAU91155.1 - 6.3e-06 26.0 0.0 2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase NB-ARC PF00931.17 EAU91155.1 - 1.2e-05 24.2 0.1 2.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.1 EAU91155.1 - 0.00047 19.7 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EAU91155.1 - 0.0012 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EAU91155.1 - 0.0013 17.9 0.0 0.0013 17.9 0.0 1.7 2 0 0 2 2 1 1 Zeta toxin DUF2075 PF09848.4 EAU91155.1 - 0.0018 17.3 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EAU91155.1 - 0.0024 17.5 0.1 0.0088 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EAU91155.1 - 0.0034 16.4 0.1 0.038 13.0 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EAU91155.1 - 0.0058 16.3 0.7 0.025 14.3 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain KAP_NTPase PF07693.9 EAU91155.1 - 0.0066 15.4 0.9 0.11 11.4 0.0 2.1 1 1 1 2 2 2 1 KAP family P-loop domain cobW PF02492.14 EAU91155.1 - 0.0085 15.5 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zot PF05707.7 EAU91155.1 - 0.0086 15.5 0.0 0.029 13.8 0.0 1.9 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) PIF1 PF05970.9 EAU91155.1 - 0.0087 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase IstB_IS21 PF01695.12 EAU91155.1 - 0.0097 15.3 1.7 2.8 7.3 0.1 2.6 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.1 EAU91155.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EAU91155.1 - 0.021 14.3 0.0 0.062 12.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EAU91155.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EAU91155.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 NTPase TIP49 PF06068.8 EAU91155.1 - 0.035 12.8 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus UvrD-helicase PF00580.16 EAU91155.1 - 0.05 12.8 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EAU91155.1 - 0.085 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Helicase Miro PF08477.8 EAU91155.1 - 0.09 13.2 0.2 0.22 12.0 0.2 1.7 1 1 0 1 1 1 0 Miro-like protein Torsin PF06309.6 EAU91155.1 - 0.095 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Torsin ResIII PF04851.10 EAU91155.1 - 0.14 12.0 0.1 0.45 10.3 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit WD40 PF00400.27 EAU91158.2 - 5.8e-21 73.5 18.5 2.6e-05 23.9 0.4 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EAU91158.2 - 0.032 13.7 0.0 10 5.7 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EAU91158.2 - 0.15 10.2 0.0 0.26 9.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) RrnaAD PF00398.15 EAU91159.1 - 7.3e-20 71.0 0.0 1.4e-19 70.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Git3 PF11710.3 EAU91160.2 - 1.3e-08 34.6 6.3 2.9e-08 33.5 4.3 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EAU91160.2 - 0.006 16.3 0.5 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EAU91160.2 - 0.011 14.8 5.4 0.013 14.6 2.3 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) RDD PF06271.7 EAU91160.2 - 0.78 9.6 11.2 0.3 10.9 4.4 2.5 1 1 1 2 2 2 0 RDD family RseC_MucC PF04246.7 EAU91160.2 - 1.1 8.8 4.2 1.9 8.0 0.1 2.7 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Glyoxal_oxid_N PF07250.6 EAU91161.1 - 1.3e-38 132.4 0.0 7.4e-36 123.4 0.0 3.4 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EAU91161.1 - 1.4e-22 79.6 0.0 2.4e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EAU91161.1 - 0.00013 21.6 6.1 0.088 12.5 0.1 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Pkinase PF00069.20 EAU91162.2 - 5e-23 81.5 0.0 1.2e-22 80.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91162.2 - 1.3e-14 53.9 0.0 1.1e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 EAU91162.2 - 0.036 13.4 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.2 EAU91163.1 - 4.5e-06 26.2 1.4 1.5e-05 24.6 1.0 2.0 1 0 0 1 1 1 1 F-box-like Glyco_hydro_92 PF07971.7 EAU91164.2 - 6.1e-121 404.5 0.2 8.1e-121 404.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF3528 PF12045.3 EAU91164.2 - 0.072 13.2 0.6 0.55 10.3 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3528) TrbI PF03743.9 EAU91165.2 - 0.068 12.6 0.2 11 5.4 0.1 2.8 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein GPI2 PF06432.6 EAU91169.2 - 1.2e-56 192.1 9.5 1.2e-46 159.3 2.7 2.4 2 1 1 3 3 3 2 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1345 PF07077.6 EAU91169.2 - 0.043 13.3 5.5 0.06 12.8 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1345) CAV_VP3 PF04771.7 EAU91169.2 - 0.06 13.3 0.3 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Chicken anaemia virus VP-3 protein DUF3357 PF11837.3 EAU91169.2 - 0.099 12.4 0.6 7.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) ILVD_EDD PF00920.16 EAU91170.2 - 1e-196 654.4 0.0 1.3e-196 654.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_11 PF13414.1 EAU91171.2 - 6.8e-22 76.9 3.6 4e-12 45.5 0.1 3.4 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EAU91171.2 - 7.7e-17 60.1 0.9 1.8e-05 24.0 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU91171.2 - 7.3e-16 56.7 1.4 0.00013 21.6 0.1 4.5 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU91171.2 - 7.2e-13 48.8 5.1 2.8e-10 40.5 0.1 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAU91171.2 - 3.7e-09 36.0 0.4 0.032 14.4 0.0 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU91171.2 - 2e-08 34.0 3.0 0.0005 19.9 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU91171.2 - 2.3e-07 30.1 0.1 0.78 9.6 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU91171.2 - 7.1e-07 29.3 11.9 0.01 16.3 0.0 5.8 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU91171.2 - 1.2e-06 28.7 3.9 0.047 14.0 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU91171.2 - 3.7e-06 26.3 0.8 0.2 11.5 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EAU91171.2 - 0.00024 21.3 0.3 1.9 9.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAU91171.2 - 0.00064 19.5 1.6 0.92 9.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.9 EAU91171.2 - 0.017 14.3 0.6 0.034 13.3 0.0 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_15 PF13429.1 EAU91171.2 - 0.044 12.8 6.0 0.054 12.5 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 EAU91174.2 - 3.8e-44 150.6 0.0 5.9e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Pheromone PF08015.6 EAU91176.2 - 1.5e-05 25.6 0.3 0.001 19.8 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone p450 PF00067.17 EAU91179.2 - 1.1e-62 212.1 0.0 5.4e-62 209.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 SHS2_Rpb7-N PF03876.12 EAU91180.1 - 8.4e-10 38.6 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pam16 PF03656.8 EAU91181.2 - 3.3e-14 52.7 0.0 7.5e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Pam16 DnaJ PF00226.26 EAU91181.2 - 0.095 12.4 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 DnaJ domain PALP PF00291.20 EAU91182.1 - 1.3e-64 218.3 0.3 1.5e-64 218.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.16 EAU91183.1 - 1.4e-77 258.9 0.0 1.6e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EAU91183.1 - 2.8e-13 49.5 0.0 3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EAU91183.1 - 8.9e-12 44.3 1.1 7.8e-08 31.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EAU91183.1 - 9.9e-12 44.4 0.0 1.2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EAU91183.1 - 7.1e-10 38.4 0.0 8.6e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EAU91183.1 - 1.8e-07 31.6 0.0 2.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAU91183.1 - 0.00014 21.7 0.1 0.00033 20.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EAU91183.1 - 0.012 14.7 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase L27 PF02828.11 EAU91183.1 - 0.072 12.7 0.3 0.17 11.5 0.1 1.7 2 0 0 2 2 2 0 L27 domain LRR_4 PF12799.2 EAU91184.1 - 9.3e-18 63.4 13.5 8.7e-07 28.4 0.0 5.1 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU91184.1 - 2e-12 46.6 12.7 4.1e-09 36.0 0.6 3.6 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EAU91184.1 - 1.4e-07 30.5 14.2 0.79 9.9 0.1 6.3 5 1 1 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EAU91184.1 - 0.26 11.6 13.0 15 6.3 0.0 5.4 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 EAU91184.1 - 2 8.7 15.6 8.3 6.8 0.8 5.2 5 1 1 6 6 6 0 Leucine Rich repeat Aldo_ket_red PF00248.16 EAU91187.1 - 1.2e-51 175.2 0.0 1.4e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family E1-E2_ATPase PF00122.15 EAU91188.2 - 1.4e-73 246.7 3.4 1.4e-73 246.7 2.3 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EAU91188.2 - 1.6e-38 132.0 2.0 3.9e-38 130.8 1.4 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EAU91188.2 - 2.2e-29 103.4 0.0 7.5e-29 101.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAU91188.2 - 2.8e-15 56.0 0.0 5.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EAU91188.2 - 1.2e-14 54.8 0.0 4.5e-14 53.0 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EAU91188.2 - 4.4e-14 51.6 0.0 3.6e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EAU91188.2 - 0.0003 20.4 3.6 0.0026 17.3 1.3 2.3 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 EAU91188.2 - 0.00057 19.4 0.1 0.00057 19.4 0.1 3.0 4 0 0 4 4 4 1 Positive regulator of sigma(E), RseC/MucC RhoGEF PF00621.15 EAU91189.2 - 5.5e-36 124.1 0.0 1.5e-35 122.7 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain Prominin PF05478.6 EAU91189.2 - 0.02 12.4 0.1 0.033 11.7 0.1 1.3 1 0 0 1 1 1 0 Prominin DASH_Dad2 PF08654.5 EAU91189.2 - 2.6 8.0 7.2 0.11 12.5 0.9 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 FAD_binding_4 PF01565.18 EAU91190.2 - 2.6e-09 36.6 0.3 0.00028 20.3 0.1 3.8 3 1 0 3 3 3 2 FAD binding domain BBE PF08031.7 EAU91190.2 - 1.9e-07 30.8 0.1 3.5e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EAU91190.2 - 0.00028 20.1 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding ALO PF04030.9 EAU91190.2 - 0.099 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Ank_2 PF12796.2 EAU91192.1 - 5.7e-22 77.8 0.2 1.3e-13 51.0 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EAU91192.1 - 3.6e-15 55.6 1.3 9.4e-07 28.8 0.1 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU91192.1 - 3.6e-14 51.4 1.1 2e-05 24.3 0.0 3.6 2 1 0 3 3 3 3 Ankyrin repeat Ank PF00023.25 EAU91192.1 - 4.5e-13 48.2 0.2 7.3e-07 28.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EAU91192.1 - 2.4e-11 43.8 2.7 0.0012 19.2 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) GntP_permease PF02447.11 EAU91193.2 - 0.48 8.8 3.9 1.3 7.3 1.5 2.2 2 0 0 2 2 2 0 GntP family permease zf-CHY PF05495.7 EAU91194.2 - 1.8e-16 60.0 20.0 2.3e-16 59.6 13.9 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.9 EAU91194.2 - 0.0089 15.6 1.3 0.03 13.9 0.9 1.9 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS C1_4 PF07975.7 EAU91194.2 - 0.047 13.7 4.4 0.047 13.7 3.0 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain Cys_rich_KTR PF14205.1 EAU91194.2 - 0.12 11.8 8.2 2.2 7.7 0.1 2.4 1 1 1 2 2 2 0 Cysteine-rich KTR Tmemb_55A PF09788.4 EAU91194.2 - 0.13 11.4 6.5 0.16 11.1 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_2 PF13240.1 EAU91194.2 - 0.16 11.5 7.6 0.16 11.4 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EAU91194.2 - 0.42 10.4 10.9 8.6 6.2 4.4 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain SIR2 PF02146.12 EAU91194.2 - 0.47 10.1 3.7 0.66 9.6 2.6 1.2 1 0 0 1 1 1 0 Sir2 family DZR PF12773.2 EAU91194.2 - 0.69 9.7 12.2 4.2 7.2 8.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon Cytochrome_C7 PF14522.1 EAU91194.2 - 0.82 9.3 10.9 1.5 8.4 7.5 1.5 1 0 0 1 1 1 0 Cytochrome c7 Zn-ribbon_8 PF09723.5 EAU91194.2 - 1.3 9.0 14.4 0.084 12.8 2.8 2.7 2 1 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 EAU91194.2 - 1.6 8.4 10.1 1.2 8.8 4.8 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EAU91194.2 - 1.7 7.9 7.9 20 4.5 5.5 2.6 1 1 0 1 1 1 0 zinc-ribbon domain LIM PF00412.17 EAU91194.2 - 2.1 8.4 14.2 4.1 7.5 8.2 2.2 1 1 1 2 2 2 0 LIM domain DNA_RNApol_7kD PF03604.8 EAU91194.2 - 3.5 7.1 7.6 30 4.1 3.5 3.0 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_3 PF14369.1 EAU91194.2 - 4.8 7.2 9.3 0.54 10.2 1.9 2.6 1 1 2 3 3 3 0 zinc-finger FCH PF00611.18 EAU91195.2 - 1.2e-17 63.8 0.0 3.3e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EAU91195.2 - 3.2e-11 42.4 0.1 5.4e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU91195.2 - 6.2e-09 35.3 0.0 1.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU91195.2 - 5.2e-05 22.6 0.0 9.3e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain IncA PF04156.9 EAU91195.2 - 1.1 8.8 9.1 1.6 8.3 4.8 2.4 1 1 0 2 2 2 0 IncA protein Clat_adaptor_s PF01217.15 EAU91197.1 - 1.9e-15 56.8 0.0 3.6e-15 55.9 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_tranf_2_3 PF13641.1 EAU91198.2 - 0.11 12.3 0.1 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 RRM_6 PF14259.1 EAU91199.1 - 6.7e-35 118.8 2.8 3.5e-10 39.7 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU91199.1 - 1e-30 105.1 3.7 1.4e-10 40.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU91199.1 - 1e-19 70.1 0.1 3.9e-05 23.4 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU91199.1 - 2.4e-05 24.1 0.1 0.093 12.5 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EAU91199.1 - 0.11 12.3 0.0 23 4.8 0.0 3.3 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif N2227 PF07942.7 EAU91201.1 - 2.8e-64 216.7 0.0 3.8e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EAU91201.1 - 0.00075 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU91201.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Tcp11 PF05794.8 EAU91202.2 - 1.7e-07 30.3 0.0 4.2e-06 25.7 0.0 2.6 2 1 0 2 2 2 1 T-complex protein 11 Lyase_aromatic PF00221.14 EAU91203.2 - 2e-157 524.4 4.5 2.6e-157 524.0 3.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase eIF2_C PF09173.6 EAU91203.2 - 5.5e-05 23.1 0.0 0.065 13.2 0.0 2.6 2 0 0 2 2 2 2 Initiation factor eIF2 gamma, C terminal Cation_efflux PF01545.16 EAU91204.2 - 2.2e-58 197.5 0.5 3e-58 197.1 0.4 1.2 1 0 0 1 1 1 1 Cation efflux family Fe-ADH PF00465.14 EAU91205.2 - 6.3e-68 229.0 0.0 7.7e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EAU91205.2 - 1e-17 64.2 0.0 1.7e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF770 PF05591.7 EAU91205.2 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF770) Flavin_Reduct PF01613.13 EAU91206.2 - 1.8e-17 63.6 0.1 2.8e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Amidohydro_1 PF01979.15 EAU91207.2 - 1.9e-26 93.5 0.0 6.8e-25 88.4 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EAU91207.2 - 1.3e-25 91.0 0.1 2.6e-25 90.0 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EAU91207.2 - 6.7e-12 45.0 0.1 1.7e-11 43.7 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EAU91207.2 - 4.7e-08 32.6 0.0 0.00062 19.0 0.0 2.6 2 1 1 3 3 3 2 Amidohydrolase family Aldo_ket_red PF00248.16 EAU91208.1 - 1.1e-64 217.9 0.0 1.3e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EAU91209.1 - 7.1e-61 205.4 0.1 8.2e-61 205.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-RING_2 PF13639.1 EAU91210.2 - 3.1e-13 49.2 8.0 5.5e-13 48.5 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EAU91210.2 - 2.9e-06 27.3 3.2 5.5e-06 26.3 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EAU91210.2 - 2.1e-05 24.2 1.7 3.8e-05 23.4 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EAU91210.2 - 9e-05 22.4 7.9 0.00018 21.4 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU91210.2 - 0.00017 21.2 6.0 0.00031 20.4 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EAU91210.2 - 0.00048 19.7 3.9 0.00096 18.7 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EAU91210.2 - 0.0012 18.7 3.5 0.0029 17.5 2.4 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 EAU91210.2 - 0.0045 16.5 5.5 0.0074 15.8 3.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.2 EAU91210.2 - 0.11 12.5 5.2 0.2 11.7 3.6 1.4 1 0 0 1 1 1 0 RING-variant domain zf-MIZ PF02891.15 EAU91210.2 - 0.54 9.8 11.4 2 8.0 7.9 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Josephin PF02099.12 EAU91211.1 - 7.5e-50 168.6 0.0 1.7e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 Josephin UIM PF02809.15 EAU91211.1 - 0.44 10.2 24.4 0.38 10.4 1.5 4.4 4 0 0 4 4 4 0 Ubiquitin interaction motif DUF572 PF04502.8 EAU91211.1 - 1.1 8.4 14.6 0.14 11.3 6.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) ATG27 PF09451.5 EAU91213.2 - 1.4e-42 145.7 0.0 1.9e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EAU91213.2 - 1.4e-05 24.2 0.0 3.8e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Mannose-6-phosphate receptor Cauli_VI PF01693.11 EAU91214.1 - 3.9e-14 52.3 0.1 3.7e-08 33.2 0.1 2.3 2 0 0 2 2 2 2 Caulimovirus viroplasmin PSD4 PF07631.6 EAU91215.2 - 0.1 12.9 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) DASH_Duo1 PF08651.5 EAU91217.2 - 1.2e-13 50.4 0.0 2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1510 PF07423.6 EAU91217.2 - 4 6.7 11.4 0.96 8.7 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DEAD PF00270.24 EAU91218.1 - 3.9e-37 127.3 0.0 8.1e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EAU91218.1 - 7.5e-22 76.9 2.8 4.9e-21 74.3 1.9 2.5 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EAU91218.1 - 2e-20 72.4 0.2 6.1e-20 70.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TGT PF01702.13 EAU91219.2 - 1.4e-85 286.4 0.0 1.7e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase TIM-br_sig_trns PF09370.5 EAU91219.2 - 0.11 11.5 0.0 6.3 5.7 0.0 2.2 2 0 0 2 2 2 0 TIM-barrel signal transduction protein EMP70 PF02990.11 EAU91220.2 - 4.5e-179 596.2 0.5 1e-177 591.7 0.4 2.0 1 1 0 1 1 1 1 Endomembrane protein 70 tRNA-synt_1b PF00579.20 EAU91221.1 - 1.5e-71 240.9 0.0 1.9e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosom_S12_S23 PF00164.20 EAU91222.1 - 1.3e-39 134.4 0.7 1.5e-39 134.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transglut_core PF01841.14 EAU91224.1 - 3.4e-10 40.1 0.0 8.9e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EAU91224.1 - 0.095 11.9 0.0 2.4 7.4 0.0 2.3 2 1 1 3 3 3 0 Transglutaminase-like domain CTP_transf_1 PF01148.15 EAU91225.1 - 1.5e-76 257.4 23.1 1.9e-76 257.1 16.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family SEEEED PF14797.1 EAU91225.1 - 0.69 10.0 10.5 1 9.5 7.3 1.1 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Topoisom_I_N PF02919.10 EAU91226.2 - 3.8e-98 327.0 6.3 3.8e-98 327.0 4.4 3.5 3 2 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EAU91226.2 - 5.1e-73 245.0 5.9 1.8e-72 243.2 4.1 2.0 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EAU91226.2 - 7e-32 108.9 0.1 2.9e-31 106.9 0.1 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EAU91226.2 - 0.0061 15.7 0.9 0.017 14.3 0.0 2.0 2 0 0 2 2 2 1 RolB/RolC glucosidase family HAD_2 PF13419.1 EAU91227.1 - 5.6e-30 104.8 0.1 1.2e-29 103.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU91227.1 - 0.0053 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like RE_AccI PF09545.5 EAU91227.1 - 0.025 13.1 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease Hydrolase PF00702.21 EAU91227.1 - 0.053 13.9 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PALP PF00291.20 EAU91228.2 - 2.2e-76 257.0 0.2 2.8e-76 256.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EAU91228.2 - 6.4e-45 150.6 0.0 1.3e-26 91.9 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF3301 PF11743.3 EAU91228.2 - 0.048 13.1 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) Vps8 PF12816.2 EAU91230.2 - 9.9e-69 230.5 0.0 3.6e-68 228.6 0.0 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EAU91230.2 - 6.4e-05 22.5 0.3 0.068 12.7 0.0 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 EAU91230.2 - 0.035 14.0 0.0 0.44 10.5 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Arc PF03869.9 EAU91230.2 - 0.039 13.5 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 Arc-like DNA binding domain Herpes_UL16 PF03044.9 EAU91230.2 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family COG2 PF06148.6 EAU91231.2 - 8.4e-30 103.3 4.5 8.4e-30 103.3 3.1 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 EAU91231.2 - 4e-19 68.9 0.2 2e-18 66.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 EAU91231.2 - 0.00022 20.9 1.0 0.0011 18.7 0.5 2.4 1 1 0 1 1 1 1 Vps51/Vps67 DUF2450 PF10475.4 EAU91231.2 - 0.0046 15.8 2.0 0.0083 15.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 EAU91231.2 - 0.0097 15.5 8.0 0.033 13.7 5.6 1.9 1 0 0 1 1 1 1 IncA protein Allexi_40kDa PF05549.6 EAU91231.2 - 0.025 13.8 0.5 0.064 12.5 0.3 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein GrpE PF01025.14 EAU91231.2 - 0.24 10.9 4.0 0.7 9.4 2.8 1.8 1 1 0 1 1 1 0 GrpE Hemerythrin PF01814.18 EAU91232.2 - 2.9e-17 63.0 8.0 3.8e-17 62.7 5.5 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Aminotran_5 PF00266.14 EAU91235.1 - 2.3e-30 105.5 0.0 2.5e-28 98.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EAU91235.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Uso1_p115_head PF04869.9 EAU91236.2 - 3.1e-43 147.7 0.0 2.3e-42 144.8 0.0 2.4 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EAU91236.2 - 7.2e-09 35.6 17.6 1.3e-08 34.8 12.2 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Cnd1 PF12717.2 EAU91236.2 - 0.018 14.9 0.6 0.045 13.5 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 FlxA PF14282.1 EAU91236.2 - 0.062 13.2 12.8 0.16 11.8 8.9 1.6 1 0 0 1 1 1 0 FlxA-like protein COMP PF11598.3 EAU91236.2 - 0.087 12.9 1.0 0.28 11.2 0.4 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.5 EAU91236.2 - 0.15 12.1 6.3 0.39 10.8 4.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 EAU91236.2 - 0.6 10.0 13.7 1.1 9.2 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) MerR-DNA-bind PF09278.6 EAU91236.2 - 1.1 9.6 6.9 10 6.6 0.1 3.3 3 0 0 3 3 3 0 MerR, DNA binding V_ATPase_I PF01496.14 EAU91236.2 - 1.2 6.8 6.7 1.6 6.5 4.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EAU91236.2 - 1.3 8.9 10.9 2.9 7.7 7.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EAU91236.2 - 3.7 6.5 8.9 6.1 5.8 6.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BTV_NS2 PF04514.7 EAU91236.2 - 7.9 5.2 14.0 11 4.8 9.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Clathrin_lg_ch PF01086.12 EAU91237.1 - 4.8e-44 150.9 7.7 4.6e-41 141.1 3.5 2.0 1 1 1 2 2 2 2 Clathrin light chain DUF4407 PF14362.1 EAU91237.1 - 0.28 10.1 8.1 0.36 9.7 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PGP_phosphatase PF09419.5 EAU91238.1 - 6e-35 120.0 0.0 1.2e-32 112.5 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EAU91238.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like Abhydrolase_6 PF12697.2 EAU91239.1 - 3.9e-23 82.5 0.0 4.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU91239.1 - 7.1e-20 71.2 0.0 1.3e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAU91239.1 - 1.1e-19 69.9 0.2 5.2e-19 67.8 0.1 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EAU91239.1 - 0.0001 21.6 0.0 0.056 12.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EAU91239.1 - 0.00014 21.4 0.3 0.0063 16.1 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EAU91239.1 - 0.0011 18.6 0.0 0.0034 16.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) AXE1 PF05448.7 EAU91239.1 - 0.0046 15.4 0.2 0.014 13.8 0.1 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EAU91239.1 - 0.0091 15.4 0.2 0.26 10.6 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 EAU91239.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 EAU91239.1 - 0.018 14.3 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.9 EAU91239.1 - 0.06 12.5 0.0 0.68 9.0 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase PAF-AH_p_II PF03403.8 EAU91239.1 - 0.1 10.8 0.3 6.5 4.9 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase_phd PF10503.4 EAU91239.1 - 0.13 11.4 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase ABC_membrane PF00664.18 EAU91240.2 - 1.1e-44 152.8 0.9 1.5e-44 152.4 0.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EAU91240.2 - 6.6e-32 110.6 0.0 1.5e-31 109.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EAU91240.2 - 0.00022 20.5 1.3 0.0046 16.2 0.0 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EAU91240.2 - 0.00024 21.1 0.0 0.033 14.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain SbcCD_C PF13558.1 EAU91240.2 - 0.011 15.5 0.3 0.047 13.6 0.2 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Tcp11 PF05794.8 EAU91240.2 - 0.065 11.9 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 T-complex protein 11 DUF258 PF03193.11 EAU91240.2 - 0.13 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Peptidase_S46 PF10459.4 EAU91241.2 - 0.02 13.3 1.6 0.022 13.1 1.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Sec15 PF04091.7 EAU91241.2 - 0.1 11.9 1.0 3.8 6.7 0.2 2.3 1 1 1 2 2 2 0 Exocyst complex subunit Sec15-like EcsC PF12787.2 EAU91241.2 - 0.94 8.8 3.3 1.6 8.0 0.3 2.1 2 0 0 2 2 2 0 EcsC protein family QCR10 PF09796.4 EAU91242.1 - 3.7e-12 45.7 0.1 4.6e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Nop16 PF09420.5 EAU91243.2 - 1.3e-34 119.7 2.6 1.4e-33 116.3 1.8 2.0 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 Rsa3 PF14615.1 EAU91243.2 - 0.097 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosome-assembly protein 3 NUDIX PF00293.23 EAU91244.1 - 9.3e-17 60.9 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EAU91244.1 - 1.9e-11 44.1 0.0 6.2e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EAU91244.1 - 0.0054 16.2 1.7 0.012 15.1 1.2 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NTF2 PF02136.15 EAU91245.1 - 3.8e-06 27.2 0.3 4.5e-06 27.0 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.2 EAU91245.1 - 1.4e-05 25.4 0.2 1.7e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EAU91245.1 - 0.0029 17.4 0.2 0.0034 17.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain ATG19_autophagy PF12744.2 EAU91245.1 - 0.094 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding DUF4440 PF14534.1 EAU91245.1 - 0.098 12.8 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EAU91246.1 - 2.7e-05 24.5 0.0 3.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2529 PF10740.4 EAU91246.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) Peptidase_S24 PF00717.18 EAU91246.1 - 0.098 12.3 0.2 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 Peptidase S24-like SnoaL_2 PF12680.2 EAU91249.2 - 0.00023 21.5 0.0 0.00034 20.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EAU91249.2 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EAU91250.1 - 0.0096 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EAU91250.1 - 0.036 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase DUF4440 PF14534.1 EAU91250.1 - 0.089 13.0 0.0 0.18 12.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) ubiquitin PF00240.18 EAU91252.2 - 1.4e-08 33.9 0.2 4.6e-08 32.3 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EAU91252.2 - 7.3e-07 29.3 0.1 2.5e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EAU91252.2 - 0.0033 17.0 0.0 0.03 13.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like USP7_ICP0_bdg PF12436.3 EAU91252.2 - 0.055 12.7 0.0 0.056 12.6 0.0 1.0 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 UN_NPL4 PF11543.3 EAU91252.2 - 0.14 12.4 0.0 0.15 12.3 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Gryzun PF07919.7 EAU91254.1 - 2.4e-79 267.1 0.2 3.1e-79 266.7 0.1 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EAU91254.1 - 3.5e-47 160.9 0.1 1e-45 156.1 0.0 2.6 2 1 0 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.1 EAU91254.1 - 3.5e-05 23.6 1.3 0.025 14.4 0.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TRAPPC10 PF12584.3 EAU91254.1 - 0.00016 21.1 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 EAU91254.1 - 0.00076 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_7 PF13176.1 EAU91254.1 - 0.072 12.9 1.5 0.2 11.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAU91254.1 - 0.11 12.8 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EAU91254.1 - 0.12 12.2 0.4 0.46 10.3 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2225 PF09986.4 EAU91254.1 - 0.18 11.2 0.1 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 EAU91254.1 - 0.36 10.8 6.1 0.22 11.5 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU91254.1 - 1 9.1 6.4 0.22 11.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat GST_N_3 PF13417.1 EAU91255.1 - 3.2e-24 84.9 0.0 6e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU91255.1 - 7.2e-18 64.3 0.0 1.7e-17 63.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAU91255.1 - 5.3e-08 32.9 0.1 8.9e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU91255.1 - 7.5e-08 32.1 0.1 2.3e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU91255.1 - 0.00016 21.5 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EAU91255.1 - 0.056 13.9 0.0 0.094 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M43 PF05572.8 EAU91256.1 - 7.4e-18 64.6 0.0 1.3e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EAU91256.1 - 1.1e-07 32.3 0.1 1.9e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU91256.1 - 4.6e-07 29.9 0.1 6.4e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAU91256.1 - 1e-06 28.9 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EAU91256.1 - 0.00042 19.6 0.1 0.00056 19.3 0.1 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 EAU91256.1 - 0.0029 17.1 0.1 0.0045 16.5 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU91256.1 - 0.0061 16.2 0.4 0.009 15.7 0.2 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EAU91256.1 - 0.046 12.5 0.1 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Abhydrolase_3 PF07859.8 EAU91257.2 - 5.2e-37 127.4 0.1 1.1e-32 113.2 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU91257.2 - 1.7e-08 33.5 0.0 2.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAU91257.2 - 6.1e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EAU91257.2 - 0.014 14.1 0.6 0.095 11.3 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family APH PF01636.18 EAU91258.1 - 3.1e-36 125.3 0.0 4.2e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU91258.1 - 3.6e-06 26.7 0.0 5.5e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 EAU91258.1 - 0.0011 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase HSP70 PF00012.15 EAU91259.1 - 1.4e-265 881.9 12.9 1.6e-265 881.7 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EAU91259.1 - 2.7e-13 49.2 6.2 2.2e-12 46.2 0.4 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 EAU91259.1 - 0.00014 21.6 6.9 0.65 9.8 0.0 4.7 4 1 0 4 4 4 2 Cell division protein FtsA DUF1748 PF08520.5 EAU91259.1 - 0.1 12.2 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) KfrA_N PF11740.3 EAU91259.1 - 2.3 8.7 8.4 15 6.0 0.3 2.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term F-box PF00646.28 EAU91260.2 - 4.6e-08 32.5 0.0 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU91260.2 - 0.0015 18.2 0.2 0.0031 17.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EAU91260.2 - 0.0033 17.1 0.2 0.006 16.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like domain Hexapep PF00132.19 EAU91261.1 - 2.4e-13 48.9 17.7 2e-08 33.3 1.6 4.3 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EAU91261.1 - 2e-08 33.6 12.5 5.9e-07 28.9 2.3 3.8 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EAU91261.1 - 0.002 16.7 0.1 0.0028 16.2 0.1 1.2 1 0 0 1 1 1 1 L-fucokinase DUF1301 PF06979.7 EAU91262.1 - 0.076 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) FMN_dh PF01070.13 EAU91264.2 - 3.4e-121 404.4 0.1 4.2e-121 404.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EAU91264.2 - 1.1e-23 82.7 0.0 2.7e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EAU91264.2 - 3.9e-05 22.7 0.0 6.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EAU91264.2 - 0.0012 17.8 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain PEP_mutase PF13714.1 EAU91265.1 - 1e-44 152.5 3.3 1.2e-44 152.3 2.3 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EAU91265.1 - 2.7e-19 68.8 0.6 3.6e-19 68.3 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family F-box PF00646.28 EAU91266.2 - 0.00039 19.9 0.1 0.0016 18.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU91266.2 - 0.00045 19.8 0.1 0.0016 18.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like Cas_Cas4 PF01930.12 EAU91267.1 - 0.005 16.7 0.3 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 EAU91267.1 - 0.044 13.1 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF1778 PF08681.6 EAU91267.1 - 0.078 12.8 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) DUF1128 PF06569.6 EAU91267.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) F-box-like PF12937.2 EAU91269.1 - 2.3e-06 27.2 0.2 2.3e-06 27.2 0.2 2.8 3 0 0 3 3 3 1 F-box-like DivIC PF04977.10 EAU91269.1 - 0.038 13.4 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF1470 PF07336.6 EAU91269.1 - 1.5 9.1 7.9 0.73 10.1 3.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1470) DUF221 PF02714.10 EAU91270.2 - 3.8e-80 269.1 16.2 3.8e-80 269.1 11.3 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAU91270.2 - 1.2e-36 125.6 1.9 2.4e-36 124.6 0.1 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EAU91270.2 - 4.2e-11 43.2 0.0 1.3e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF809 PF05663.6 EAU91270.2 - 1.8 8.5 3.0 2.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF809) APS_kinase PF01583.15 EAU91278.1 - 3.6e-71 237.9 0.0 4.4e-71 237.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EAU91278.1 - 1.8e-08 34.3 0.0 3.8e-08 33.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EAU91278.1 - 2.4e-06 28.3 0.0 6.2e-06 27.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EAU91278.1 - 9.7e-05 22.6 0.0 0.00015 22.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAU91278.1 - 0.0036 16.7 0.0 0.0062 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 EAU91278.1 - 0.0062 15.7 0.0 0.0073 15.5 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EAU91278.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EAU91278.1 - 0.12 11.8 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EAU91278.1 - 0.12 12.6 0.0 0.15 12.3 0.0 1.3 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 EAU91278.1 - 0.12 11.9 0.2 0.29 10.7 0.1 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Pkinase PF00069.20 EAU91279.2 - 1.1e-68 231.2 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91279.2 - 4.7e-49 166.8 0.0 6.3e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU91279.2 - 5.1e-05 22.3 0.0 8.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU91279.2 - 0.00027 20.0 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU91279.2 - 0.0046 16.7 0.0 0.59 9.8 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EAU91279.2 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Hexapep PF00132.19 EAU91280.1 - 1.2e-11 43.5 1.1 0.00014 21.1 1.0 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EAU91280.1 - 2e-07 31.2 0.0 3.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EAU91280.1 - 2.8e-07 30.0 0.0 1.5e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EAU91280.1 - 0.045 13.3 6.1 0.074 12.6 1.9 2.5 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase tRNA-synt_2c PF01411.14 EAU91282.2 - 4.6e-205 682.0 0.0 6e-205 681.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EAU91282.2 - 1.4e-16 60.0 0.2 3.1e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EAU91282.2 - 8.9e-08 31.7 0.5 3.9e-07 29.6 0.3 2.3 1 0 0 1 1 1 1 DHHA1 domain CLASP_N PF12348.3 EAU91283.2 - 6.2e-20 71.5 0.0 9.6e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 CLASP N terminal O-antigen_lig PF13425.1 EAU91284.1 - 0.098 12.6 0.2 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Asp PF00026.18 EAU91285.2 - 4.2e-60 203.6 0.2 5.4e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EAU91285.2 - 3e-06 27.2 0.7 8.8e-06 25.7 0.2 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal PTPLA PF04387.9 EAU91286.1 - 6.8e-54 181.7 5.6 1.2e-53 180.9 3.9 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA NIF PF03031.13 EAU91287.2 - 5.8e-41 139.7 0.0 1.1e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase bZIP_1 PF00170.16 EAU91288.2 - 9.7e-05 22.2 10.4 9.7e-05 22.2 7.2 3.2 2 1 1 3 3 3 1 bZIP transcription factor Dapper PF15268.1 EAU91288.2 - 1 8.1 28.2 1.6 7.4 19.6 1.3 1 0 0 1 1 1 0 Dapper DUF4110 PF13422.1 EAU91288.2 - 2.1 8.2 13.7 1.7 8.5 0.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) Poty_PP PF08440.5 EAU91288.2 - 8.6 5.3 16.8 4.9 6.1 7.4 2.0 2 0 0 2 2 2 0 Potyviridae polyprotein TPP1 PF10341.4 EAU91289.2 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD IncA PF04156.9 EAU91290.2 - 0.2 11.2 37.9 0.053 13.1 19.1 2.6 2 1 1 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 EAU91290.2 - 3 7.6 33.6 0.63 9.8 13.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 EAU91290.2 - 3.9 7.9 10.6 12 6.3 1.1 3.9 2 1 1 3 3 3 0 SlyX AAA_13 PF13166.1 EAU91290.2 - 4 5.7 20.8 7.1 4.9 14.4 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EAU91290.2 - 4.1 5.1 18.6 0.12 10.1 7.8 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Striatin PF08232.7 EAU91290.2 - 4.4 7.6 22.0 10 6.4 4.6 2.8 1 1 1 2 2 2 0 Striatin family DUF745 PF05335.8 EAU91290.2 - 5.9 6.3 17.4 0.32 10.4 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Borrelia_P83 PF05262.6 EAU91290.2 - 5.9 5.0 18.8 9.1 4.4 13.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein NIF PF03031.13 EAU91291.2 - 4e-53 179.3 0.5 5.9e-53 178.7 0.3 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TMF_DNA_bd PF12329.3 EAU91292.2 - 0.0076 16.0 15.6 0.0076 16.0 10.8 8.5 5 2 3 8 8 8 4 TATA element modulatory factor 1 DNA binding BTB PF00651.26 EAU91293.2 - 7.1e-12 45.3 0.0 8.9e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain CENP-T PF15511.1 EAU91293.2 - 0.0041 16.4 9.7 0.0044 16.3 5.5 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T RhoGAP PF00620.22 EAU91294.2 - 4e-41 140.1 0.1 1.3e-40 138.4 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EAU91294.2 - 4.6e-13 49.0 29.6 1.7e-08 34.4 5.7 3.4 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 EAU91294.2 - 1e-06 28.3 7.0 1e-06 28.3 4.8 4.1 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Paired_CXXCH_1 PF09699.5 EAU91294.2 - 0.015 14.8 7.5 0.2 11.1 2.9 2.8 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF972 PF06156.8 EAU91294.2 - 0.3 11.4 8.6 0.37 11.1 0.6 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF972) TMF_TATA_bd PF12325.3 EAU91294.2 - 0.8 9.4 8.4 0.31 10.7 2.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding RICH PF05062.7 EAU91294.2 - 1.2 9.3 4.2 2.2 8.4 0.6 2.7 2 0 0 2 2 2 0 RICH domain TPR_MLP1_2 PF07926.7 EAU91294.2 - 1.5 8.5 11.1 91 2.8 7.5 3.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.17 EAU91294.2 - 6 6.9 9.0 1.3 9.0 0.4 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain KTI12 PF08433.5 EAU91295.2 - 3.3e-78 262.6 0.0 3.9e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EAU91295.2 - 1.8e-11 44.1 0.0 2.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU91295.2 - 0.0094 16.7 0.0 0.015 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU91295.2 - 0.0096 16.2 0.0 0.023 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain CAF-1_p150 PF11600.3 EAU91296.2 - 0.00061 19.2 41.6 0.00061 19.2 28.8 5.6 5 2 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Helitron_like_N PF14214.1 EAU91301.2 - 2.2e-67 226.3 0.0 5.2e-67 225.1 0.0 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DNA_primase_S PF01896.14 EAU91312.2 - 1.8e-51 173.7 0.1 2.6e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit GrpE PF01025.14 EAU91313.2 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 GrpE Adaptin_N PF01602.15 EAU91314.2 - 5.7e-24 84.3 0.7 3.7e-22 78.3 0.0 2.6 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 EAU91314.2 - 2e-05 24.7 0.8 0.035 14.3 0.1 4.2 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EAU91314.2 - 0.0024 17.7 0.3 0.8 9.5 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Profilin PF00235.14 EAU91314.2 - 0.0077 16.3 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 Profilin RabGAP-TBC PF00566.13 EAU91315.1 - 4.6e-40 137.3 0.0 5.9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBF PF01758.11 EAU91316.2 - 6.6e-47 159.3 11.7 6.6e-47 159.3 8.1 2.8 3 0 0 3 3 3 1 Sodium Bile acid symporter family Col_cuticle_N PF01484.12 EAU91317.1 - 0.3 10.8 2.9 3.9 7.2 0.0 2.7 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain bZIP_1 PF00170.16 EAU91318.1 - 3.5e-06 26.8 6.8 7.6e-06 25.7 4.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAU91318.1 - 0.0071 16.1 7.2 0.014 15.2 5.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 EAU91318.1 - 0.0077 15.2 0.2 0.013 14.4 0.2 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ERM PF00769.14 EAU91318.1 - 0.018 14.6 0.7 0.023 14.2 0.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AA_permease PF00324.16 EAU91319.2 - 6.9e-49 166.4 15.3 8.8e-49 166.1 10.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAU91319.2 - 1e-12 47.3 15.8 1.3e-12 47.0 11.0 1.0 1 0 0 1 1 1 1 Amino acid permease IU_nuc_hydro PF01156.14 EAU91320.2 - 2.4e-33 115.7 0.0 3.3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase WD40 PF00400.27 EAU91321.1 - 8.6e-63 206.1 23.3 7.5e-12 44.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAU91321.1 - 7.3e-05 21.0 8.2 0.017 13.2 0.3 3.9 2 1 1 3 3 3 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 EAU91321.1 - 0.00028 19.8 0.0 0.19 10.6 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EAU91321.1 - 0.0037 15.6 0.1 0.38 8.9 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EAU91321.1 - 0.0078 15.8 0.3 16 5.2 0.0 4.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF1416 PF07210.7 EAU91321.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) R3H-assoc PF13902.1 EAU91322.2 - 0.055 13.4 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 R3H-associated N-terminal domain Got1 PF04178.7 EAU91323.2 - 4.3e-21 75.2 13.2 4.8e-21 75.0 9.1 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EAU91323.2 - 0.091 11.7 6.6 0.13 11.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Pkinase PF00069.20 EAU91327.2 - 2.1e-36 125.4 0.0 7.5e-35 120.3 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91327.2 - 1.8e-17 63.2 0.0 3.3e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU91327.2 - 0.029 13.3 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Cyclin PF08613.6 EAU91328.2 - 6.1e-18 65.6 0.1 1.1e-17 64.8 0.1 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EAU91328.2 - 0.0086 15.6 0.1 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.9 EAU91329.1 - 4.8e-18 64.3 0.0 7.3e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EAU91329.1 - 7.4e-13 48.4 0.5 1.3e-12 47.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pab87_oct PF13969.1 EAU91329.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Pab87 octamerisation domain Bacteriocin_IIc PF10439.4 EAU91330.2 - 0.27 11.4 2.7 6.5 6.9 0.5 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Antimicrobial10 PF08105.6 EAU91331.2 - 0.99 9.0 4.9 2.5 7.8 0.1 3.0 3 0 0 3 3 3 0 Metchnikowin family GET2 PF08690.5 EAU91334.1 - 1.2 8.2 5.7 2.2 7.4 3.9 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Palm_thioest PF02089.10 EAU91335.2 - 5.4e-56 189.5 0.0 1.5e-55 188.1 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 EAU91335.2 - 0.0019 17.8 0.0 0.008 15.7 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Nucleos_tra2_C PF07662.8 EAU91338.1 - 7.3e-66 221.6 8.3 7.3e-66 221.6 5.8 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EAU91338.1 - 1.4e-15 57.3 5.1 1.4e-15 57.3 3.5 3.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EAU91338.1 - 0.0015 18.4 6.1 0.0015 18.4 4.3 3.3 4 0 0 4 4 4 1 Nucleoside recognition CAAD PF14159.1 EAU91338.1 - 1.6 8.4 9.4 0.93 9.1 0.3 3.2 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase WD40 PF00400.27 EAU91339.1 - 1.8e-19 68.8 2.7 2.1e-06 27.3 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat MPC PF03650.8 EAU91342.1 - 4.2e-40 136.4 0.1 5.3e-40 136.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF3421 PF11901.3 EAU91343.1 - 1e-25 89.7 0.0 2.2e-13 49.9 0.0 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 EAU91343.1 - 5e-06 26.0 2.5 5e-06 26.0 1.8 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain CD99L2 PF12301.3 EAU91343.1 - 0.037 13.7 4.6 0.056 13.1 3.2 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF4366 PF14283.1 EAU91343.1 - 0.088 12.2 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tetraspannin PF00335.15 EAU91344.1 - 0.1 11.8 22.2 0.019 14.2 10.2 2.0 1 1 1 2 2 2 0 Tetraspanin family XPG_I PF00867.13 EAU91346.2 - 5.9e-19 67.9 0.0 1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EAU91346.2 - 0.033 14.4 0.0 0.099 12.9 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain Peptidase_M22 PF00814.20 EAU91347.1 - 8.9e-75 251.6 0.0 1e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PilM_2 PF11104.3 EAU91347.1 - 0.017 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; HbrB PF08539.6 EAU91348.2 - 1.2e-34 119.4 0.0 2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 HbrB-like DUF1880 PF08976.6 EAU91348.2 - 2.4 8.3 6.4 0.66 10.1 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1880) Amidohydro_3 PF07969.6 EAU91349.2 - 3.4e-63 214.2 0.0 1.2e-62 212.4 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EAU91349.2 - 3.8e-07 30.0 0.0 1e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EAU91349.2 - 1.6e-06 28.4 0.1 0.0063 16.5 0.0 2.7 2 1 1 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EAU91349.2 - 0.042 13.6 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase zf-rbx1 PF12678.2 EAU91350.2 - 4e-14 52.4 2.0 8e-14 51.5 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EAU91350.2 - 1.9e-11 43.6 6.2 1.9e-11 43.6 4.3 2.2 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EAU91350.2 - 5.1e-07 29.2 4.5 1.2e-06 28.0 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EAU91350.2 - 2.6e-06 27.1 0.6 6.5e-06 25.9 0.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EAU91350.2 - 1.8e-05 24.6 2.2 1.8e-05 24.6 1.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU91350.2 - 2e-05 24.2 3.3 4.6e-05 23.0 2.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAU91350.2 - 0.00027 20.6 3.6 0.00027 20.6 2.5 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EAU91350.2 - 0.00027 20.5 7.0 0.00027 20.5 4.9 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EAU91350.2 - 0.0094 15.8 1.9 0.024 14.4 1.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EAU91350.2 - 0.014 15.3 0.8 0.034 14.0 0.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EAU91350.2 - 1.4 8.5 3.9 0.5 9.9 0.7 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain YqeY PF09424.5 EAU91351.1 - 7.8e-26 90.6 1.9 8.9e-26 90.4 1.3 1.1 1 0 0 1 1 1 1 Yqey-like protein PriCT_1 PF08708.6 EAU91351.1 - 0.0093 15.7 0.1 0.034 13.9 0.1 2.1 1 1 0 1 1 1 1 Primase C terminal 1 (PriCT-1) Talin_middle PF09141.5 EAU91352.2 - 0.037 13.7 0.2 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Talin, middle domain NAD_kinase PF01513.16 EAU91353.1 - 1.7e-68 230.4 0.0 3.5e-68 229.4 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DUF3069 PF11269.3 EAU91353.1 - 0.019 15.0 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) RRM_1 PF00076.17 EAU91356.2 - 5.5e-24 83.5 0.0 6.8e-24 83.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU91356.2 - 1.2e-18 66.7 0.0 1.5e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU91356.2 - 7.5e-13 48.1 0.0 9.6e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 EAU91357.1 - 7.2e-16 58.2 0.2 7.2e-16 58.2 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU91357.1 - 7.4e-06 26.2 0.1 7.4e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 HMG-box domain ALS_ss_C PF10369.4 EAU91358.2 - 1.4e-21 75.9 0.0 1.6e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EAU91358.2 - 2.3e-12 46.0 0.1 4.2e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EAU91358.2 - 9.1e-09 35.0 0.0 1.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain Dynamitin PF04912.9 EAU91359.2 - 3.3e-25 88.7 1.9 7.8e-25 87.4 1.3 1.6 1 1 0 1 1 1 1 Dynamitin DUF3584 PF12128.3 EAU91359.2 - 0.0002 18.8 2.2 0.00036 18.0 1.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Syntaxin-6_N PF09177.6 EAU91359.2 - 0.00071 19.9 2.8 0.0075 16.6 0.2 3.3 3 1 0 3 3 3 1 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.3 EAU91359.2 - 0.0012 18.5 2.9 0.068 12.9 0.6 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 EAU91359.2 - 0.0073 16.1 9.9 0.25 11.1 4.5 2.7 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 EAU91359.2 - 0.014 15.2 7.7 0.083 12.7 0.9 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YPEB PF14620.1 EAU91359.2 - 0.045 12.7 1.4 0.066 12.2 0.1 1.8 2 1 0 2 2 2 0 YpeB sporulation Bcr-Abl_Oligo PF09036.5 EAU91359.2 - 0.075 13.0 0.1 0.25 11.3 0.0 2.0 2 0 0 2 2 1 0 Bcr-Abl oncoprotein oligomerisation domain Reo_sigmaC PF04582.7 EAU91359.2 - 0.11 11.6 1.5 0.48 9.5 0.1 2.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Spc24 PF08286.6 EAU91359.2 - 0.12 12.1 2.3 0.62 9.7 0.3 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Laminin_II PF06009.7 EAU91359.2 - 0.12 12.0 4.4 0.14 11.8 1.3 2.4 3 1 0 3 3 3 0 Laminin Domain II TPR_MLP1_2 PF07926.7 EAU91359.2 - 0.21 11.3 7.7 0.056 13.1 1.0 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 EAU91359.2 - 0.27 11.2 2.8 0.28 11.2 0.2 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG COG2 PF06148.6 EAU91359.2 - 0.96 9.3 6.1 1.1 9.1 0.4 3.3 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 EAU91359.2 - 1.6 8.8 8.4 0.16 12.0 1.0 2.9 3 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Utp12 PF04003.7 EAU91359.2 - 1.8 8.5 6.5 0.28 11.1 0.2 2.7 3 1 1 4 4 3 0 Dip2/Utp12 Family TBPIP PF07106.8 EAU91359.2 - 2.3 7.7 6.3 0.56 9.7 0.4 2.6 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NTR2 PF15458.1 EAU91359.2 - 8.4 5.5 9.9 0.7 9.0 1.2 2.8 3 1 1 4 4 4 0 Nineteen complex-related protein 2 STE3 PF02076.10 EAU91360.1 - 1.2e-94 316.6 13.8 1.4e-94 316.3 9.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mannosyl_trans2 PF04188.8 EAU91361.1 - 1.6e-59 201.9 18.4 2e-59 201.6 12.8 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Pex24p PF06398.6 EAU91362.1 - 5.7e-32 110.8 17.9 5.1e-31 107.7 12.4 2.2 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2109 PF09882.4 EAU91362.1 - 0.12 12.2 0.3 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) DUF3684 PF12449.3 EAU91364.2 - 0 1345.1 0.2 0 1344.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EAU91364.2 - 0.0023 17.6 0.0 0.0071 15.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EAU91364.2 - 0.049 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.10 EAU91365.2 - 7.5e-244 810.0 0.0 1e-243 809.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EAU91365.2 - 2.8e-15 56.7 0.0 3.9e-13 49.7 0.0 2.2 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EAU91365.2 - 8e-15 55.0 6.3 8e-15 55.0 4.4 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EAU91365.2 - 2.9e-07 30.1 0.0 6e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EAU91365.2 - 3.1e-05 23.3 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EAU91365.2 - 0.16 11.6 0.0 5 6.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 LETM1 PF07766.8 EAU91367.2 - 2.1e-20 72.9 1.5 7.6e-12 44.8 0.1 2.1 1 1 1 2 2 2 2 LETM1-like protein Med27 PF11571.3 EAU91368.2 - 1.4e-07 31.5 0.1 3.1e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 27 Endotoxin_N PF03945.9 EAU91368.2 - 0.0083 15.5 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 2 delta endotoxin, N-terminal domain DOCK-C2 PF14429.1 EAU91370.2 - 1.2e-45 155.4 0.0 2.8e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EAU91370.2 - 3.8e-34 117.5 0.2 1e-33 116.1 0.1 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis DASH_Spc34 PF08657.5 EAU91371.2 - 1.4e-05 24.8 3.0 0.035 13.7 0.0 3.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 IL11 PF07400.6 EAU91371.2 - 0.0012 18.4 0.5 0.0034 16.9 0.3 1.8 1 0 0 1 1 1 1 Interleukin 11 Spectrin PF00435.16 EAU91371.2 - 0.01 16.0 1.2 0.025 14.8 0.9 1.7 1 0 0 1 1 1 0 Spectrin repeat GAS PF13851.1 EAU91371.2 - 0.011 14.9 2.4 0.018 14.2 1.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.4 EAU91371.2 - 0.028 12.8 0.2 0.049 12.0 0.1 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.7 EAU91371.2 - 0.04 14.1 0.2 0.5 10.6 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FemAB PF02388.11 EAU91371.2 - 0.074 11.7 2.2 0.12 11.0 1.5 1.2 1 0 0 1 1 1 0 FemAB family DUF2130 PF09903.4 EAU91371.2 - 0.18 10.4 3.4 0.18 10.5 1.5 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) IncA PF04156.9 EAU91371.2 - 0.25 10.9 6.2 0.53 9.8 4.3 1.5 1 0 0 1 1 1 0 IncA protein DUF2802 PF10975.3 EAU91371.2 - 0.43 10.3 0.0 0.43 10.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) Swi5 PF07061.6 EAU91371.2 - 0.43 10.3 2.1 1.2 8.9 0.0 2.7 1 1 1 2 2 2 0 Swi5 DUF904 PF06005.7 EAU91371.2 - 2 8.7 6.2 6.6 7.1 0.4 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF904) DivIC PF04977.10 EAU91371.2 - 3 7.4 8.6 4.9 6.7 2.1 3.1 2 1 1 3 3 3 0 Septum formation initiator APG5 PF04106.7 EAU91372.1 - 4e-48 163.5 0.0 4.9e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Dfp1_Him1_M PF08630.5 EAU91373.2 - 2.3e-25 88.7 0.1 7e-25 87.2 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EAU91373.2 - 9.3e-21 73.2 0.2 2.2e-20 72.0 0.2 1.7 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EAU91373.2 - 5.3e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EAU91373.2 - 0.0058 16.4 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain tRNA_synt_1c_R2 PF04557.10 EAU91373.2 - 0.49 11.1 7.4 6.1 7.6 0.3 3.0 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SAM_decarbox PF01536.11 EAU91374.1 - 1.4e-84 283.6 0.0 2.9e-83 279.2 0.0 2.1 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1279 PF06916.8 EAU91375.1 - 1.6e-19 69.9 0.0 2.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Rax2 PF12768.2 EAU91377.1 - 7.3e-94 314.1 12.5 1.3e-74 250.9 1.6 5.3 4 1 1 5 5 5 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 EAU91377.1 - 8.2e-11 41.1 0.0 1.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU91377.1 - 2.5e-09 36.5 0.2 5.1e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kelch_6 PF13964.1 EAU91377.1 - 2.9e-06 27.2 7.4 0.54 10.5 0.0 7.0 8 0 0 8 8 8 2 Kelch motif Kelch_2 PF07646.10 EAU91377.1 - 4.1e-05 23.1 0.3 0.15 11.9 0.1 4.7 3 0 0 3 3 3 1 Kelch motif SH3_2 PF07653.12 EAU91377.1 - 0.00023 20.5 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Kelch_1 PF01344.20 EAU91377.1 - 0.00046 19.6 0.2 1.9 8.1 0.0 4.4 4 0 0 4 4 4 1 Kelch motif EphA2_TM PF14575.1 EAU91377.1 - 0.27 11.6 0.0 0.61 10.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Tmemb_9 PF05434.6 EAU91377.1 - 0.41 10.3 0.0 0.7 9.6 0.0 1.2 1 0 0 1 1 1 0 TMEM9 zf-C2H2_2 PF12756.2 EAU91378.1 - 2.2e-37 127.2 7.5 8.3e-31 106.1 0.1 3.2 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EAU91378.1 - 3.5e-11 42.8 3.0 1.8e-10 40.6 2.1 2.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAU91378.1 - 2.9e-08 33.6 2.8 2.9e-08 33.6 1.9 3.8 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 EAU91378.1 - 0.01 15.5 0.6 0.01 15.5 0.4 3.0 3 0 0 3 3 3 1 DBF zinc finger zf-C2H2_4 PF13894.1 EAU91378.1 - 0.035 14.4 0.4 0.035 14.4 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger DUF3449 PF11931.3 EAU91378.1 - 0.04 13.4 0.0 0.04 13.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) zf-C2H2 PF00096.21 EAU91378.1 - 0.068 13.5 1.2 0.068 13.5 0.8 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-FCS PF06467.9 EAU91378.1 - 0.069 12.7 2.1 9.5 5.9 0.0 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-LYAR PF08790.6 EAU91378.1 - 0.09 12.4 2.0 6 6.6 0.3 2.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF629 PF04780.7 EAU91378.1 - 0.098 11.1 1.2 3.8 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-UBP PF02148.14 EAU91378.1 - 0.26 11.4 4.0 2.3 8.3 0.1 3.2 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein AKAP95 PF04988.7 EAU91378.1 - 0.77 9.5 4.2 4.5 7.0 0.0 2.7 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-BED PF02892.10 EAU91378.1 - 0.89 9.3 9.8 0.046 13.4 0.8 2.7 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 EAU91378.1 - 2.5 8.1 7.3 2.1 8.3 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger HeH PF12949.2 EAU91379.1 - 1.1e-05 24.8 0.8 1.9e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.22 EAU91379.1 - 0.00036 19.9 1.1 0.0027 17.1 0.1 2.7 2 1 0 2 2 2 1 SAP domain Armet PF10208.4 EAU91379.1 - 0.045 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Vinculin PF01044.14 EAU91379.1 - 0.22 9.5 6.6 0.29 9.0 4.6 1.1 1 0 0 1 1 1 0 Vinculin family Herpes_DNAp_acc PF04929.7 EAU91379.1 - 1.8 7.4 9.5 0.73 8.7 5.4 1.3 1 1 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.9 EAU91379.1 - 6.1 4.7 7.0 7.1 4.5 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CBFB_NFYA PF02045.10 EAU91380.1 - 5e-28 97.4 6.3 5e-28 97.4 4.4 2.5 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CAP_N PF01213.14 EAU91380.1 - 4 6.6 9.1 8.6 5.5 6.3 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal tRNA_synt_1c_R2 PF04557.10 EAU91382.2 - 0.081 13.6 4.6 0.12 13.1 3.1 1.4 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 WWE PF02825.15 EAU91383.2 - 0.11 11.9 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 WWE domain Phage_int_SAM_1 PF02899.12 EAU91389.2 - 0.0024 18.0 0.7 1.2 9.3 0.0 3.2 2 1 1 3 3 3 2 Phage integrase, N-terminal SAM-like domain Abhydrolase_5 PF12695.2 EAU91389.2 - 0.06 13.0 0.0 0.49 10.1 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family RRM_2 PF04059.7 EAU91390.2 - 8e-34 115.5 0.6 1.4e-33 114.7 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EAU91390.2 - 4.3e-06 26.2 0.4 0.021 14.4 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU91390.2 - 1.5e-05 24.8 0.7 0.0013 18.6 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU91390.2 - 0.15 11.8 0.6 2.6 7.9 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_3 PF07859.8 EAU91391.2 - 1.4e-23 83.6 0.0 2.9e-23 82.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU91391.2 - 8.4e-09 34.5 0.0 2.3e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) StbA PF06406.6 EAU91391.2 - 0.089 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 StbA protein DUF2974 PF11187.3 EAU91391.2 - 0.2 11.0 0.1 0.32 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MCM PF00493.18 EAU91392.2 - 2.1e-138 460.6 0.2 3e-138 460.1 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EAU91392.2 - 3.7e-32 111.4 26.3 3.7e-32 111.4 18.2 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EAU91392.2 - 1.3e-16 61.1 0.0 4e-16 59.5 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAU91392.2 - 1.2e-07 31.0 0.0 3.5e-06 26.3 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAU91392.2 - 1.1e-05 25.2 0.1 3.5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EAU91392.2 - 0.00083 18.9 0.1 0.017 14.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EAU91392.2 - 0.0024 17.3 0.1 0.02 14.3 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain HHH_2 PF12826.2 EAU91392.2 - 0.0084 15.9 0.0 4.5 7.2 0.0 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif Yippee-Mis18 PF03226.9 EAU91392.2 - 0.036 14.0 0.1 0.09 12.8 0.1 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1250 PF06855.7 EAU91392.2 - 0.079 12.4 0.1 6.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Sorting_nexin PF03700.8 EAU91392.2 - 0.63 10.1 5.7 0.29 11.2 1.9 2.0 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain CHCH PF06747.8 EAU91393.2 - 1.6e-06 27.8 6.0 2.5e-06 27.2 4.1 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EAU91393.2 - 0.0021 18.1 3.0 0.0038 17.3 2.1 1.3 1 0 0 1 1 1 1 GCK domain Feld-I_B PF09252.5 EAU91393.2 - 0.047 13.6 0.2 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 Allergen Fel d I-B chain PRCC PF10253.4 EAU91393.2 - 4.5 7.9 10.3 0.082 13.6 1.4 1.9 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Sec7 PF01369.15 EAU91395.2 - 1.1e-25 90.3 0.0 1.9e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PC4 PF02229.11 EAU91397.1 - 8.3e-22 76.1 0.4 1.8e-21 75.1 0.3 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Ribosomal_L18e PF00828.14 EAU91397.1 - 0.0027 18.0 0.3 0.0042 17.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DUF4122 PF13498.1 EAU91397.1 - 0.0029 17.0 0.0 0.0053 16.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4122) DUF4236 PF14020.1 EAU91397.1 - 0.071 13.2 0.2 0.2 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) DUF2890 PF11081.3 EAU91397.1 - 0.18 11.8 7.9 0.21 11.6 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TFIIF_alpha PF05793.7 EAU91397.1 - 0.54 8.5 19.9 0.65 8.2 13.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sarcoglycan_2 PF05510.8 EAU91397.1 - 1.4 7.1 3.8 1.7 6.8 2.6 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Hid1 PF12722.2 EAU91397.1 - 6.3 4.3 7.4 6.8 4.2 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EAU91397.1 - 8.1 4.3 9.1 10 4.0 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MRI PF15325.1 EAU91397.1 - 9.5 7.2 15.5 20 6.1 10.7 1.6 1 1 0 1 1 1 0 Modulator of retrovirus infection HECT PF00632.20 EAU91398.2 - 9.2e-91 304.2 0.0 1.7e-90 303.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EAU91398.2 - 3.3e-80 269.6 0.0 3.3e-80 269.6 0.0 6.4 6 0 0 6 6 6 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EAU91398.2 - 2.7e-67 227.4 0.1 2.9e-66 224.0 0.0 2.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EAU91398.2 - 9e-31 105.9 7.9 9e-31 105.9 5.5 4.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4414) Arm PF00514.18 EAU91398.2 - 0.073 12.9 0.7 2.8 7.9 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ADH_zinc_N PF00107.21 EAU91399.2 - 1.2e-31 108.9 0.2 1.9e-31 108.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU91399.2 - 6.3e-11 43.2 0.0 1.3e-10 42.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU91399.2 - 8.8e-07 28.6 0.0 4.9e-06 26.2 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EAU91399.2 - 0.057 12.9 0.5 0.09 12.3 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Myb_DNA-binding PF00249.26 EAU91400.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF702 PF05142.7 EAU91400.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) AMP-binding PF00501.23 EAU91401.2 - 5.5e-94 314.9 0.0 6.9e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU91401.2 - 2.1e-13 51.0 0.3 5.3e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_A_bac PF01000.21 EAU91402.2 - 9.1e-29 99.8 0.0 1.6e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EAU91402.2 - 2.2e-10 39.5 0.0 3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EAU91402.2 - 0.096 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF22 MS_channel PF00924.13 EAU91403.1 - 2.9e-24 85.5 0.3 6.3e-24 84.4 0.2 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EAU91403.1 - 0.0059 15.8 0.1 0.014 14.6 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EAU91403.1 - 0.27 11.2 2.2 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain SNARE PF05739.14 EAU91404.2 - 8.6e-15 54.1 0.3 2.4e-14 52.7 0.2 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EAU91404.2 - 5.2e-12 45.8 0.2 7.1e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Syntaxin zf-FPG_IleRS PF06827.9 EAU91405.1 - 0.42 10.3 6.4 5.1 6.8 2.3 3.2 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-FCS PF06467.9 EAU91405.1 - 2.3 7.9 13.8 4.9 6.8 1.8 2.6 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif TF_Zn_Ribbon PF08271.7 EAU91405.1 - 6.1 6.2 7.3 30 4.0 5.1 2.3 1 1 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EAU91405.1 - 8.2 5.7 15.3 1.7 7.9 3.6 3.5 1 1 2 3 3 3 0 zinc-ribbon domain Fe_hyd_lg_C PF02906.9 EAU91406.1 - 4.3e-72 242.7 0.0 1.9e-71 240.6 0.0 1.9 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Aa_trans PF01490.13 EAU91408.2 - 2.4e-77 260.1 24.1 2.8e-77 259.9 16.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EAU91408.2 - 7.6e-06 24.9 3.5 7.6e-06 24.9 2.4 2.6 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Polysacc_synt_C PF14667.1 EAU91408.2 - 0.00017 21.4 1.9 0.00017 21.4 1.3 3.4 3 1 2 5 5 5 1 Polysaccharide biosynthesis C-terminal domain DUF2574 PF10836.3 EAU91408.2 - 0.064 12.9 0.4 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2574) DUF962 PF06127.6 EAU91408.2 - 0.11 12.3 1.0 0.46 10.4 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Ferrochelatase PF00762.14 EAU91411.1 - 5.2e-100 334.4 0.0 5.8e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.12 EAU91411.1 - 0.024 14.7 0.0 3.1 7.9 0.0 3.0 3 0 0 3 3 3 0 CbiX UNC-79 PF14776.1 EAU91411.1 - 0.064 11.6 0.0 0.088 11.1 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 WD40 PF00400.27 EAU91412.1 - 8e-32 107.9 4.2 1.3e-08 34.3 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EAU91412.1 - 0.00055 19.4 0.3 0.0023 17.4 0.2 2.0 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 EAU91412.1 - 0.015 14.8 0.3 11 5.7 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat Nup160 PF11715.3 EAU91412.1 - 0.016 13.3 0.9 7 4.6 0.0 3.7 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 EAU91412.1 - 0.041 12.5 0.0 0.21 10.1 0.0 1.9 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) WD40 PF00400.27 EAU91413.1 - 0.014 15.2 0.7 0.12 12.3 0.2 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Velvet PF11754.3 EAU91414.2 - 5.1e-31 107.8 0.0 8.3e-31 107.1 0.0 1.3 1 1 0 1 1 1 1 Velvet factor Ten1_2 PF15490.1 EAU91415.1 - 0.0011 18.5 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Ribosomal_S7 PF00177.16 EAU91418.1 - 1.6e-39 134.8 0.9 2e-39 134.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-C4_ClpX PF06689.8 EAU91420.1 - 0.026 14.0 0.4 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger Gelsolin PF00626.17 EAU91421.2 - 0.0013 18.3 0.1 0.015 14.9 0.0 2.5 2 0 0 2 2 2 1 Gelsolin repeat Disulph_isomer PF06491.6 EAU91421.2 - 0.066 13.0 0.0 0.31 10.9 0.0 2.2 1 0 0 1 1 1 0 Disulphide isomerase Nse4_C PF08743.5 EAU91422.2 - 8.7e-24 83.3 0.2 2.7e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EAU91422.2 - 4.1e-17 61.7 0.3 7.7e-17 60.8 0.2 1.5 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE KA1 PF02149.14 EAU91422.2 - 0.12 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase associated domain 1 SNF2_N PF00176.18 EAU91423.2 - 8.5e-66 221.7 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EAU91423.2 - 2e-17 63.0 0.0 5.2e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 EAU91423.2 - 4.4e-10 39.6 0.0 1.1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 EAU91423.2 - 2.2e-09 37.0 0.0 3e-08 33.3 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU91423.2 - 1.3e-05 25.0 0.0 2.6e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WW PF00397.21 EAU91423.2 - 0.14 12.0 0.6 0.32 10.9 0.4 1.7 1 0 0 1 1 1 0 WW domain Acetyltransf_3 PF13302.1 EAU91424.2 - 2.1e-15 57.1 0.0 2.7e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU91424.2 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EAU91424.2 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU91424.2 - 0.054 13.4 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ARPC4 PF05856.7 EAU91425.2 - 1.1e-77 259.2 5.1 1.2e-77 259.1 3.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.23 EAU91426.1 - 4.5e-33 113.1 0.1 4.5e-33 113.1 0.1 1.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Hex_IIIa PF02455.11 EAU91426.1 - 0.25 9.9 2.5 0.34 9.5 1.8 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) p450 PF00067.17 EAU91427.2 - 6.2e-60 203.0 0.0 8.7e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 EAU91428.1 - 3.1e-33 115.5 2.3 3.9e-33 115.1 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EAU91428.1 - 2.2e-25 89.4 3.4 3.1e-25 89.0 2.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EAU91428.1 - 9.7e-12 44.9 1.9 3.2e-11 43.2 1.3 1.7 1 1 0 1 1 1 1 KR domain ThiF PF00899.16 EAU91428.1 - 0.0035 17.1 0.1 0.01 15.6 0.1 1.7 1 1 0 1 1 1 1 ThiF family Methyltransf_25 PF13649.1 EAU91428.1 - 0.014 15.7 0.0 0.051 13.9 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain E1-E2_ATPase PF00122.15 EAU91429.2 - 4.7e-32 110.8 0.1 9.8e-32 109.8 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EAU91429.2 - 3.6e-23 82.7 0.0 6.7e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU91429.2 - 3.3e-22 79.9 0.0 6.3e-21 75.7 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EAU91429.2 - 7.2e-19 67.7 0.0 1.7e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase_like2 PF13246.1 EAU91429.2 - 5.6e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EAU91429.2 - 0.0033 16.8 0.0 0.0086 15.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EAU91429.2 - 0.0045 16.5 0.1 0.033 13.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sel1 PF08238.7 EAU91431.2 - 4.1e-31 106.7 41.3 1.7e-06 28.4 1.3 11.0 10 1 0 10 10 10 6 Sel1 repeat TPR_11 PF13414.1 EAU91431.2 - 0.00064 19.3 8.7 0.33 10.6 0.1 4.4 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.1 EAU91431.2 - 0.028 15.0 0.4 0.028 15.0 0.3 6.6 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU91431.2 - 0.073 13.5 12.6 5.3 7.7 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU91431.2 - 0.091 12.7 0.1 0.091 12.7 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2615 PF11027.3 EAU91431.2 - 0.21 11.5 0.0 0.49 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) TPR_14 PF13428.1 EAU91431.2 - 0.67 10.7 0.1 0.67 10.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU91431.2 - 5.8 6.9 9.0 1.2 9.1 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SWIB PF02201.13 EAU91432.1 - 1.3e-26 92.0 0.7 2.2e-26 91.3 0.1 1.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DUF572 PF04502.8 EAU91432.1 - 0.053 12.7 11.8 0.071 12.3 8.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DEK_C PF08766.6 EAU91432.1 - 0.13 12.0 0.2 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 DEK C terminal domain RNA_pol_Rpc82 PF05645.8 EAU91432.1 - 0.55 9.7 8.3 0.039 13.4 1.4 1.9 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 SRP-alpha_N PF04086.8 EAU91432.1 - 2.9 7.1 12.7 4.4 6.5 8.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Menin PF05053.8 EAU91432.1 - 4.5 5.3 6.7 5.9 4.9 4.7 1.3 1 0 0 1 1 1 0 Menin FlxA PF14282.1 EAU91432.1 - 5.8 6.9 10.5 0.046 13.6 1.2 2.0 3 0 0 3 3 3 0 FlxA-like protein Cut8_N PF14482.1 EAU91432.1 - 8.5 6.4 10.0 37 4.4 6.9 2.2 1 1 0 1 1 1 0 Cut8 proteasome-binding domain Aldo_ket_red PF00248.16 EAU91434.2 - 1.9e-72 243.4 0.0 2.1e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank PF00023.25 EAU91435.2 - 6.7e-13 47.7 0.1 2.7e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EAU91435.2 - 1e-12 48.1 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EAU91435.2 - 1.4e-11 44.2 0.0 4.3e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank_5 PF13857.1 EAU91435.2 - 3.1e-10 39.9 0.2 7e-08 32.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU91435.2 - 1.9e-08 33.7 0.1 0.0093 16.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EAU91435.2 - 2e-08 34.5 0.2 8.1e-08 32.5 0.2 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ran_BP1 PF00638.13 EAU91436.1 - 1.2e-10 41.4 0.4 2e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 EAU91436.1 - 1.4e-07 31.7 0.7 1.4e-07 31.7 0.5 7.6 7 2 2 9 9 9 1 NUP50 (Nucleoporin 50 kDa) PGA2 PF07543.7 EAU91437.1 - 6.6 6.5 14.6 20 4.9 10.1 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 Methyltransf_6 PF03737.10 EAU91438.2 - 3.4e-21 75.7 0.7 1.1e-19 70.7 0.5 2.3 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase VanZ PF04892.7 EAU91442.2 - 1.6e-07 31.3 1.2 3.1e-07 30.4 0.8 1.5 1 1 0 1 1 1 1 VanZ like family DUF1275 PF06912.6 EAU91442.2 - 0.056 12.6 2.1 0.076 12.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) TauE PF01925.14 EAU91442.2 - 0.18 11.1 1.0 0.29 10.5 0.4 1.5 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Amidohydro_4 PF13147.1 EAU91444.1 - 1.4e-22 81.0 7.6 5.7e-21 75.7 1.2 3.3 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EAU91444.1 - 2.2e-11 44.0 0.3 4.6e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EAU91444.1 - 1.8e-08 34.0 4.7 2.8e-07 30.2 0.2 3.5 3 1 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EAU91444.1 - 6.3e-07 28.9 1.3 1.3e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family Med1 PF10744.4 EAU91444.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Mucin PF01456.12 EAU91445.2 - 0.074 12.8 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2678 PF10856.3 EAU91445.2 - 6.5 6.5 10.4 0.8 9.4 3.8 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2678) AFG1_ATPase PF03969.11 EAU91446.2 - 1.2e-47 162.5 0.0 8.8e-47 159.6 0.0 2.0 1 1 0 1 1 1 1 AFG1-like ATPase AAA_29 PF13555.1 EAU91446.2 - 1.5e-05 24.4 0.0 3.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EAU91446.2 - 0.00033 20.5 0.0 0.00089 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU91446.2 - 0.0004 20.5 0.0 0.0028 17.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU91446.2 - 0.0018 18.3 0.0 0.0059 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EAU91446.2 - 0.034 13.5 0.2 2 7.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.1 EAU91446.2 - 0.046 13.4 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EAU91446.2 - 0.051 14.4 0.0 0.21 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EAU91446.2 - 0.14 12.3 0.0 0.88 9.7 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) HSP20 PF00011.16 EAU91448.2 - 0.0045 16.8 0.0 0.032 14.0 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family 2OG-FeII_Oxy_2 PF13532.1 EAU91450.2 - 1.9e-19 70.2 0.0 1e-18 67.8 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ATP-synt_DE_N PF02823.11 EAU91451.1 - 2.3e-21 75.3 0.2 3.2e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GCS PF03074.11 EAU91452.2 - 9.2e-166 551.4 0.0 9e-135 449.4 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 EAU91452.2 - 0.0015 17.6 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) S1 PF00575.18 EAU91452.2 - 0.064 13.3 0.2 0.26 11.3 0.0 2.2 3 0 0 3 3 3 0 S1 RNA binding domain APG6 PF04111.7 EAU91453.2 - 1.3e-115 385.8 1.9 1.6e-115 385.4 1.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Atg14 PF10186.4 EAU91453.2 - 2.8 6.7 12.9 5.6 5.8 8.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_C14 PF00656.17 EAU91454.1 - 1.4e-14 54.3 0.0 2.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain YcfA PF07927.7 EAU91457.1 - 1.6e-06 27.8 0.0 4.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 YcfA-like protein SKG6 PF08693.5 EAU91458.2 - 0.045 13.0 0.2 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.2 EAU91458.2 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VSP PF03302.8 EAU91458.2 - 0.17 10.5 0.8 0.24 10.0 0.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TMEM171 PF15471.1 EAU91458.2 - 0.73 8.5 4.9 1.7 7.3 3.4 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 Ank_2 PF12796.2 EAU91460.2 - 4.6e-06 26.8 0.0 0.026 14.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU91460.2 - 0.0022 18.4 1.1 8.6 7.0 0.0 5.3 5 1 2 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU91460.2 - 0.05 13.8 0.4 54 4.4 0.0 5.1 7 0 0 7 7 7 0 Ankyrin repeat Dimer_Tnp_hAT PF05699.9 EAU91460.2 - 5.3 6.7 10.6 21 4.8 0.0 4.6 4 2 1 5 5 5 0 hAT family C-terminal dimerisation region Glyco_transf_49 PF13896.1 EAU91462.2 - 4.6e-37 127.7 2.2 4.8e-29 101.4 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan BcrAD_BadFG PF01869.15 EAU91463.1 - 5.7e-21 75.0 0.0 8.6e-21 74.4 0.0 1.3 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Cornichon PF03311.9 EAU91464.2 - 1.4e-53 180.3 7.2 1.6e-53 180.2 5.0 1.0 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.9 EAU91465.2 - 4.9e-50 168.9 9.8 5.4e-50 168.8 6.8 1.0 1 0 0 1 1 1 1 Cornichon protein FliS PF02561.9 EAU91465.2 - 0.067 13.0 0.1 0.09 12.6 0.1 1.1 1 0 0 1 1 1 0 Flagellar protein FliS RRM_6 PF14259.1 EAU91466.2 - 0.00025 20.9 0.0 0.00059 19.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU91466.2 - 0.00055 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU91466.2 - 0.0015 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 EAU91466.2 - 0.028 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding RRM_3 PF08777.6 EAU91466.2 - 0.034 13.9 0.2 0.16 11.8 0.0 2.0 1 1 1 2 2 2 0 RNA binding motif AMP-binding PF00501.23 EAU91467.1 - 5.4e-90 301.7 0.0 7e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU91467.1 - 4e-11 43.6 0.6 2.9e-10 40.9 0.2 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Spore_III_AB PF09548.5 EAU91467.1 - 0.042 13.5 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Metallophos PF00149.23 EAU91469.2 - 1.1e-07 31.4 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EAU91469.2 - 0.064 12.4 0.0 0.25 10.4 0.0 1.8 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Scs3p PF10261.4 EAU91470.1 - 3.9e-39 134.1 12.6 3.4e-38 131.0 8.7 2.3 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 EAU91470.1 - 0.0059 16.2 0.3 0.0059 16.2 0.2 2.2 2 1 0 2 2 2 1 PAP2 superfamily ALAD PF00490.16 EAU91471.1 - 1.1e-117 392.5 0.0 1.3e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.20 EAU91472.2 - 1.2e-45 155.7 0.0 1.6e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91472.2 - 8.7e-30 103.6 0.0 1.6e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU91472.2 - 0.00027 19.9 0.0 0.00048 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU91472.2 - 0.024 14.3 0.4 0.069 12.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Homeobox PF00046.24 EAU91473.2 - 4.6e-18 64.5 3.0 7.9e-18 63.8 2.1 1.4 1 0 0 1 1 1 1 Homeobox domain FlaG PF03646.10 EAU91474.2 - 7.6 6.7 11.5 0.18 11.9 0.9 2.7 2 1 0 2 2 2 0 FlaG protein NAD_kinase PF01513.16 EAU91476.2 - 6.5e-57 192.4 0.0 8.5e-57 192.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EAU91476.2 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain XPG_I_2 PF12813.2 EAU91478.2 - 8.8e-06 25.3 0.0 2.3e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 XPG domain containing BSD PF03909.12 EAU91479.2 - 5.3e-12 45.2 0.5 1.5e-11 43.8 0.1 1.9 2 0 0 2 2 2 1 BSD domain DUF4456 PF14644.1 EAU91479.2 - 0.079 12.1 4.0 1.5 7.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4456) CENP-B_dimeris PF09026.5 EAU91479.2 - 0.4 10.9 7.4 0.66 10.2 4.2 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.8 EAU91479.2 - 8.3 4.0 9.9 13 3.3 6.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi CPSase_sm_chain PF00988.17 EAU91480.1 - 1.8e-44 150.4 0.0 2.7e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EAU91480.1 - 1.8e-35 122.1 0.0 2.6e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAU91480.1 - 1.4e-08 34.4 0.1 1.1e-07 31.4 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EAU91480.1 - 6.5e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family PB1 PF00564.19 EAU91481.2 - 0.072 12.7 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 PB1 domain NADH_B2 PF14813.1 EAU91482.1 - 0.0022 17.6 0.2 0.0023 17.5 0.2 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 SNARE_assoc PF09335.6 EAU91482.1 - 0.022 14.9 0.0 0.023 14.9 0.0 1.0 1 0 0 1 1 1 0 SNARE associated Golgi protein Metallophos PF00149.23 EAU91483.1 - 2.2e-16 59.8 2.1 3.7e-16 59.1 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EAU91483.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glycogen_syn PF05693.8 EAU91484.1 - 0 1097.7 0.0 0 1097.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 EAU91484.1 - 2.8e-08 33.5 0.1 7.6e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EAU91484.1 - 4.6e-08 32.6 0.0 0.00013 21.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAU91484.1 - 1.2e-06 28.7 0.1 3.5e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain DUF92 PF01940.11 EAU91485.2 - 5.2e-47 159.8 12.1 1.4e-46 158.4 8.4 1.6 1 1 0 1 1 1 1 Integral membrane protein DUF92 KH_1 PF00013.24 EAU91486.2 - 1.9e-69 229.1 36.3 6.1e-12 45.0 0.7 12.3 11 1 0 11 11 11 10 KH domain KH_3 PF13014.1 EAU91486.2 - 7.5e-49 162.6 24.6 8.7e-07 28.4 0.4 11.8 11 0 0 11 11 11 10 KH domain KH_2 PF07650.12 EAU91486.2 - 6.2e-09 35.2 23.3 0.065 12.7 0.1 7.1 7 1 0 7 7 7 4 KH domain SLS PF14611.1 EAU91486.2 - 3.3e-05 23.4 17.4 0.42 9.9 0.0 7.2 6 3 1 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EAU91486.2 - 0.0012 18.4 11.4 1.5 8.4 0.0 6.3 7 0 0 7 7 7 2 KH domain RRM_1 PF00076.17 EAU91487.2 - 1.9e-10 40.1 0.0 9.7e-07 28.3 0.0 3.5 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EAU91487.2 - 2.7e-08 33.3 0.1 5.6e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 EAU91487.2 - 8.3e-06 25.6 0.0 6.2e-05 22.8 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 EAU91488.1 - 8.4e-27 93.8 0.2 2.3e-25 89.1 0.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EAU91488.1 - 6e-23 80.2 15.8 1.4e-11 43.8 1.5 2.7 1 1 2 3 3 3 3 TPR repeat PPP5 PF08321.7 EAU91488.1 - 4.7e-17 61.7 0.0 9.4e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.23 EAU91488.1 - 1.5e-13 49.7 11.3 6e-08 31.9 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU91488.1 - 1.5e-09 37.2 4.4 0.0063 16.6 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU91488.1 - 7.7e-08 31.6 11.1 0.00093 18.9 0.2 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EAU91488.1 - 2.5e-06 27.2 0.4 0.0063 16.3 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU91488.1 - 3.4e-06 27.1 0.7 0.12 13.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU91488.1 - 2.1e-05 23.9 0.1 8.8e-05 22.0 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU91488.1 - 2.9e-05 24.5 4.8 0.00031 21.3 1.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU91488.1 - 0.00019 21.6 3.1 0.037 14.3 0.8 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU91488.1 - 0.018 15.1 4.0 0.14 12.3 2.8 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EAU91488.1 - 0.03 13.3 0.2 2.7 6.9 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Orthopox_F14 PF06076.7 EAU91488.1 - 0.057 13.4 0.2 0.69 10.0 0.1 2.2 2 0 0 2 2 2 0 Orthopoxvirus F14 protein TPR_6 PF13174.1 EAU91488.1 - 0.072 13.5 0.9 0.94 10.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU91488.1 - 0.081 12.8 1.1 0.19 11.6 0.7 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat SLT PF01464.15 EAU91489.2 - 2e-09 37.0 0.2 4.3e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Transglycosylase SLT domain DUF2360 PF10152.4 EAU91489.2 - 0.23 11.7 2.9 0.42 10.8 2.0 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Lamp PF01299.12 EAU91489.2 - 0.97 8.5 3.8 1.4 7.9 2.6 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Cyclin PF08613.6 EAU91491.2 - 7.4e-08 32.9 0.0 8.7e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 EAU91491.2 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Zn_clus PF00172.13 EAU91493.2 - 5.7e-08 32.5 8.3 1.2e-07 31.5 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EAU91494.2 - 3.6e-64 216.4 0.0 4.3e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91494.2 - 3.9e-43 147.4 0.0 4.9e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU91494.2 - 5.4e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EAU91494.2 - 0.033 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Acetyltransf_1 PF00583.19 EAU91495.1 - 2e-14 53.3 0.0 2.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EAU91495.1 - 1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAU91495.1 - 1.8e-09 37.5 0.1 4.6e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAU91495.1 - 2.2e-08 34.1 0.0 2.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAU91495.1 - 4.1e-05 23.6 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EAU91495.1 - 0.00031 20.9 0.0 0.00038 20.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Herpes_UL16 PF03044.9 EAU91495.1 - 0.0007 18.6 0.0 0.00089 18.3 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL16/UL94 family FR47 PF08445.5 EAU91495.1 - 0.026 14.2 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein DNA_ligase_A_M PF01068.16 EAU91496.2 - 2.2e-39 134.9 0.0 1.2e-36 126.0 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EAU91496.2 - 7.4e-39 133.3 0.0 1.7e-38 132.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EAU91496.2 - 5.8e-19 68.2 0.0 1.6e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Pyrid_oxidase_2 PF13883.1 EAU91497.1 - 4.4e-16 59.0 0.1 4.8e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BolA PF01722.13 EAU91499.2 - 1.9e-28 98.1 0.3 2.3e-28 97.9 0.2 1.1 1 0 0 1 1 1 1 BolA-like protein CPSF73-100_C PF11718.3 EAU91499.2 - 0.11 11.8 0.2 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term zf-C2H2 PF00096.21 EAU91500.2 - 3.4e-13 49.0 5.5 6.9e-07 29.2 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU91500.2 - 3.9e-10 39.5 8.0 6.3e-06 26.2 0.0 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU91500.2 - 3.8e-08 33.0 4.3 0.0024 18.0 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU91500.2 - 0.00019 21.4 1.0 0.00059 19.9 0.7 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EAU91500.2 - 0.0038 16.8 1.6 0.22 11.2 0.2 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.2 EAU91500.2 - 0.028 14.6 1.0 0.028 14.6 0.7 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EAU91500.2 - 0.033 14.1 0.9 2.5 8.1 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 EAU91500.2 - 0.2 11.4 4.1 0.15 11.8 0.5 2.2 2 0 0 2 2 2 0 BED zinc finger Pkinase PF00069.20 EAU91501.2 - 1.4e-31 109.6 0.4 2.7e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91501.2 - 2.5e-10 39.8 0.0 3.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EAU91501.2 - 0.0012 17.7 0.6 0.0018 17.1 0.4 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EAU91501.2 - 0.0074 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Homeobox PF00046.24 EAU91502.2 - 4e-16 58.3 4.6 6.9e-16 57.6 3.2 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAU91502.2 - 0.0011 18.6 0.2 0.0037 16.9 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Glyco_hydro_61 PF03443.9 EAU91503.2 - 3.7e-40 138.0 0.0 4.6e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Allantoicase PF03561.10 EAU91503.2 - 0.069 12.6 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Allantoicase repeat ABC_tran PF00005.22 EAU91504.2 - 3.2e-48 163.5 0.0 1.9e-27 96.2 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAU91504.2 - 8.6e-16 58.7 0.5 0.0049 16.8 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EAU91504.2 - 1.2e-13 50.8 0.0 2.9e-05 23.4 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EAU91504.2 - 1e-09 37.9 0.2 2.2e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 EAU91504.2 - 1.9e-07 31.6 0.1 0.00082 19.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain HEAT PF02985.17 EAU91504.2 - 2e-07 30.5 3.9 1.1 9.4 0.0 5.0 5 0 0 5 5 4 3 HEAT repeat AAA_29 PF13555.1 EAU91504.2 - 2.5e-06 26.9 1.9 0.045 13.2 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain Miro PF08477.8 EAU91504.2 - 4e-06 27.3 0.1 0.067 13.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EAU91504.2 - 8.4e-06 26.6 0.1 0.23 12.2 0.2 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EAU91504.2 - 1.2e-05 25.3 5.6 0.081 12.8 0.1 4.7 5 1 0 5 5 4 1 AAA ATPase domain HEAT_EZ PF13513.1 EAU91504.2 - 1.2e-05 25.6 1.5 0.035 14.5 0.0 4.1 3 0 0 3 3 3 1 HEAT-like repeat AAA_22 PF13401.1 EAU91504.2 - 2e-05 24.7 0.1 0.19 11.8 0.0 4.0 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EAU91504.2 - 3.4e-05 23.0 0.1 0.028 13.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EAU91504.2 - 3.5e-05 23.7 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase HEAT_2 PF13646.1 EAU91504.2 - 5.1e-05 23.4 6.6 0.091 13.0 0.5 4.1 1 1 1 2 2 2 1 HEAT repeats AAA_33 PF13671.1 EAU91504.2 - 0.00026 20.8 0.1 0.43 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EAU91504.2 - 0.00056 19.9 0.1 0.39 10.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EAU91504.2 - 0.00057 19.7 0.1 0.66 9.7 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EAU91504.2 - 0.00065 19.4 0.1 0.83 9.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EAU91504.2 - 0.0013 18.4 0.3 0.48 10.0 0.0 3.6 3 1 0 3 3 3 1 NACHT domain SbcCD_C PF13558.1 EAU91504.2 - 0.0015 18.4 0.0 1.4 8.8 0.0 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EAU91504.2 - 0.0017 17.8 1.0 1.7 8.0 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain Tudor-knot PF11717.3 EAU91504.2 - 0.0025 17.4 0.1 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain ArgK PF03308.11 EAU91504.2 - 0.0025 16.6 0.7 0.59 8.8 0.1 2.3 2 0 0 2 2 2 1 ArgK protein AAA_30 PF13604.1 EAU91504.2 - 0.0027 17.3 0.4 2.6 7.5 0.1 3.2 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.1 EAU91504.2 - 0.0036 16.7 0.1 11 5.3 0.0 3.9 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EAU91504.2 - 0.0064 16.6 0.1 4.5 7.4 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Adaptin_N PF01602.15 EAU91504.2 - 0.0079 14.5 0.4 1.8 6.7 0.1 2.8 1 1 1 2 2 2 1 Adaptin N terminal region AAA_18 PF13238.1 EAU91504.2 - 0.018 15.3 0.0 9.4 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EAU91504.2 - 0.018 14.9 0.1 3 7.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain CLASP_N PF12348.3 EAU91504.2 - 0.022 14.1 0.0 7.7 5.8 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal AAA_13 PF13166.1 EAU91504.2 - 0.022 13.2 0.0 1.1 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EAU91504.2 - 0.024 14.4 0.0 0.58 9.9 0.0 2.9 3 0 0 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EAU91504.2 - 0.032 13.9 0.3 19 4.8 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase Zeta_toxin PF06414.7 EAU91504.2 - 0.052 12.6 0.6 0.68 8.9 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 EAU91504.2 - 0.059 12.9 0.6 9.5 5.6 0.3 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 EAU91504.2 - 0.084 11.8 0.3 2.4 7.0 0.0 2.9 3 0 0 3 3 3 0 KAP family P-loop domain AAA PF00004.24 EAU91504.2 - 0.085 13.0 0.1 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 EAU91504.2 - 0.11 11.7 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 EAU91504.2 - 0.14 11.5 0.7 13 5.1 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MutS_V PF00488.16 EAU91504.2 - 0.16 11.3 0.2 11 5.2 0.0 2.4 2 0 0 2 2 2 0 MutS domain V AAA_15 PF13175.1 EAU91504.2 - 0.19 10.7 0.0 7.6 5.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain G-alpha PF00503.15 EAU91504.2 - 0.49 9.0 1.7 0.64 8.6 0.0 2.0 3 0 0 3 3 2 0 G-protein alpha subunit Acyltransferase PF01553.16 EAU91505.1 - 9.1e-10 38.0 0.0 2.1e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase NUC173 PF08161.7 EAU91507.2 - 3.5e-38 130.9 0.0 8.2e-37 126.4 0.0 2.4 2 0 0 2 2 2 1 NUC173 domain NLE PF08154.7 EAU91507.2 - 0.0047 16.9 0.1 4.8 7.2 0.0 2.7 2 0 0 2 2 2 2 NLE (NUC135) domain Cnd1 PF12717.2 EAU91507.2 - 0.086 12.6 0.8 0.42 10.4 0.4 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 zf-HC2 PF13490.1 EAU91507.2 - 0.19 11.7 0.0 5.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Putative zinc-finger PAC2 PF09754.4 EAU91508.1 - 3e-24 86.1 0.2 3.6e-24 85.8 0.1 1.4 1 1 0 1 1 1 1 PAC2 family Peptidase_C12 PF01088.16 EAU91509.1 - 3.4e-62 209.4 0.0 3.8e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ETF_alpha PF00766.14 EAU91510.1 - 5.7e-34 115.5 0.3 1.1e-33 114.6 0.2 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EAU91510.1 - 1.1e-32 113.0 1.3 1.1e-32 113.0 0.9 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain BMC PF00936.14 EAU91510.1 - 0.2 11.3 2.5 1.6 8.4 0.2 2.7 2 0 0 2 2 2 0 BMC domain Pardaxin PF07425.6 EAU91510.1 - 0.8 9.1 4.6 3.7 7.0 3.2 2.2 1 0 0 1 1 1 0 Pardaxin AAA_11 PF13086.1 EAU91511.2 - 7e-32 110.8 0.0 7.9e-31 107.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EAU91511.2 - 1.1e-12 47.7 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU91511.2 - 1.8e-07 30.7 0.1 5.4e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAU91511.2 - 4.4e-07 29.6 0.1 1.6e-05 24.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EAU91511.2 - 0.012 15.6 0.8 0.78 9.6 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 EAU91511.2 - 0.028 13.4 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EAU91511.2 - 0.051 13.3 0.0 0.23 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EAU91511.2 - 0.054 12.5 0.0 0.17 10.9 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 EAU91511.2 - 0.058 12.7 0.0 0.18 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EAU91511.2 - 0.13 11.4 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SLT PF01464.15 EAU91511.2 - 0.21 11.0 0.0 22 4.5 0.0 2.3 2 0 0 2 2 2 0 Transglycosylase SLT domain zf-RING_2 PF13639.1 EAU91512.2 - 0.1 12.4 0.0 0.1 12.4 0.0 3.8 4 0 0 4 4 4 0 Ring finger domain LCAT PF02450.10 EAU91513.2 - 4.7e-75 252.9 0.1 1.5e-74 251.3 0.1 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EAU91513.2 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EAU91513.2 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.13 EAU91513.2 - 0.041 13.1 0.1 0.16 11.2 0.1 1.9 1 1 0 1 1 1 0 Lipase (class 2) Abhydrolase_6 PF12697.2 EAU91513.2 - 0.098 12.5 0.0 0.25 11.2 0.0 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU91513.2 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DMPK_coil PF08826.5 EAU91513.2 - 0.21 11.5 1.2 0.35 10.7 0.1 1.8 2 0 0 2 2 2 0 DMPK coiled coil domain like ECSIT PF06239.6 EAU91514.1 - 0.095 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Trp_halogenase PF04820.9 EAU91515.2 - 6.2e-28 97.6 1.0 9.6e-16 57.4 0.0 2.9 2 1 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EAU91515.2 - 9.9e-11 41.2 0.0 2.2e-10 40.1 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EAU91515.2 - 3.7e-08 32.6 0.2 7.6e-06 25.0 0.1 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU91515.2 - 2.1e-06 27.6 0.8 7.7e-06 25.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU91515.2 - 2.9e-06 27.2 0.1 7.7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EAU91515.2 - 7.3e-06 24.7 0.2 3e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EAU91515.2 - 8.4e-06 25.1 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EAU91515.2 - 2.9e-05 23.1 0.1 4.4e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EAU91515.2 - 4.3e-05 23.8 0.0 0.00091 19.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EAU91515.2 - 7.2e-05 21.8 0.3 0.00014 20.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EAU91515.2 - 0.0054 15.8 0.2 0.043 12.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EAU91515.2 - 0.008 15.1 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EAU91515.2 - 0.029 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EAU91515.2 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EAU91515.2 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU91515.2 - 0.074 12.8 0.2 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 EAU91515.2 - 0.093 12.1 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EAU91515.2 - 0.18 11.6 0.3 0.46 10.3 0.2 1.7 1 0 0 1 1 1 0 ThiF family Solute_trans_a PF03619.11 EAU91516.2 - 2.1e-65 220.8 10.0 2.6e-65 220.4 7.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha IGPS PF00218.16 EAU91517.1 - 1.1e-91 306.4 0.0 2.7e-91 305.1 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EAU91517.1 - 5.6e-50 169.6 0.1 1.1e-45 155.6 0.0 2.3 1 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EAU91517.1 - 2.4e-48 164.1 0.0 3.9e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EAU91517.1 - 5.5e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EAU91517.1 - 0.23 10.9 1.7 0.92 9.0 0.0 2.7 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain Pkinase PF00069.20 EAU91518.2 - 3.9e-69 232.7 0.0 4.7e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91518.2 - 2.8e-29 102.0 0.0 3.7e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU91518.2 - 0.013 15.2 0.2 0.059 13.0 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EAU91518.2 - 0.081 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU91518.2 - 0.11 11.4 0.0 0.46 9.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Tetraspannin PF00335.15 EAU91519.1 - 4.5e-05 22.8 8.3 7.7e-05 22.0 5.8 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF4149 PF13664.1 EAU91519.1 - 4.2 7.4 9.6 1.7 8.7 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Ni_hydr_CYTB PF01292.15 EAU91519.1 - 5.1 6.4 11.8 4.8 6.5 4.4 2.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 E1-E2_ATPase PF00122.15 EAU91520.2 - 1.7e-19 69.8 0.0 3.4e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EAU91520.2 - 1.8e-18 67.4 0.0 3.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU91520.2 - 5e-15 56.4 2.2 1.3e-13 51.8 1.5 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EAU91520.2 - 7.2e-13 48.3 0.0 2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EAU91520.2 - 0.003 17.1 0.1 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydro_lipase PF04083.11 EAU91522.1 - 1.1e-23 82.3 0.1 2.3e-23 81.2 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EAU91522.1 - 4.5e-21 75.4 0.7 6.3e-21 74.9 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU91522.1 - 9.6e-11 41.9 0.4 1.7e-10 41.1 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU91522.1 - 2.1e-07 30.7 0.0 1.5e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glucosamine_iso PF01182.15 EAU91524.2 - 3.7e-22 79.0 0.0 5.9e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.7 EAU91524.2 - 0.031 14.1 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain zf-C2H2 PF00096.21 EAU91525.1 - 5.1e-24 83.1 77.1 0.00014 21.9 0.8 11.1 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU91525.1 - 1.8e-16 59.5 69.2 3.6e-06 26.9 0.8 11.7 11 1 0 11 11 11 6 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU91525.1 - 5e-14 51.5 70.6 0.024 14.9 1.9 10.4 10 0 0 10 10 10 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU91525.1 - 0.0099 16.0 1.1 0.0099 16.0 0.8 9.4 10 0 0 10 10 10 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAU91525.1 - 0.019 14.8 22.6 2.4 8.2 0.7 5.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-met PF12874.2 EAU91525.1 - 0.019 15.1 1.8 0.019 15.1 1.3 7.3 8 0 0 8 8 8 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 EAU91525.1 - 0.089 13.3 6.6 0.24 11.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (FYDLN_acid) GIT_SHD PF08518.6 EAU91529.2 - 2.2e-24 84.5 11.0 2.4e-13 49.1 0.5 3.6 4 0 0 4 4 4 2 Spa2 homology domain (SHD) of GIT AAA_13 PF13166.1 EAU91529.2 - 0.011 14.2 8.2 0.02 13.3 5.7 1.5 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 EAU91529.2 - 0.68 9.0 24.3 0.22 10.6 9.1 2.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 EAU91529.2 - 0.98 9.0 21.1 0.26 10.9 9.7 3.1 1 1 1 2 2 2 0 Mnd1 family FlaC_arch PF05377.6 EAU91529.2 - 4.4 7.2 11.8 12 5.8 2.3 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMCO5 PF14992.1 EAU91529.2 - 6.6 5.7 24.6 0.81 8.7 12.9 2.1 1 1 1 2 2 2 0 TMCO5 family adh_short PF00106.20 EAU91530.1 - 6.1e-20 71.7 0.2 7.8e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU91530.1 - 2e-07 31.0 0.0 2.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EAU91530.1 - 0.00088 19.3 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EAU91530.1 - 0.0013 18.4 0.1 0.0027 17.4 0.1 1.5 1 1 0 1 1 1 1 KR domain DUF1326 PF07040.6 EAU91530.1 - 0.061 13.0 0.1 0.087 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) 3HCDH_N PF02737.13 EAU91530.1 - 0.067 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyridoxal_deC PF00282.14 EAU91531.2 - 4.3e-115 384.1 0.0 5.2e-115 383.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.24 EAU91532.2 - 3.6e-57 192.2 0.0 1.1e-43 148.6 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EAU91532.2 - 1.4e-21 76.2 0.7 3.6e-21 74.9 0.5 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EAU91532.2 - 9.8e-13 48.4 6.3 7e-06 26.1 0.1 4.9 2 2 2 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EAU91532.2 - 1.1e-08 35.8 0.0 0.0078 17.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EAU91532.2 - 2.1e-08 34.3 0.2 0.028 14.5 0.0 4.6 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EAU91532.2 - 6.3e-07 29.2 0.0 0.014 15.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EAU91532.2 - 1.3e-06 28.3 0.0 0.061 13.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.13 EAU91532.2 - 1.9e-06 27.5 0.0 0.011 15.2 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 EAU91532.2 - 4.9e-06 26.4 0.0 0.067 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EAU91532.2 - 9.5e-06 25.3 0.1 0.15 11.6 0.0 4.0 3 1 0 3 3 3 1 NACHT domain AAA_25 PF13481.1 EAU91532.2 - 1.4e-05 24.5 0.7 2.2 7.6 0.1 4.3 2 2 2 4 4 4 1 AAA domain AAA_18 PF13238.1 EAU91532.2 - 1.6e-05 25.2 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EAU91532.2 - 2.2e-05 24.1 0.1 0.1 12.3 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain RuvB_N PF05496.7 EAU91532.2 - 2.9e-05 23.2 0.0 0.0025 16.8 0.0 3.1 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EAU91532.2 - 0.00032 20.3 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EAU91532.2 - 0.00034 19.7 0.0 0.5 9.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_2 PF07724.9 EAU91532.2 - 0.00064 19.6 0.0 0.045 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EAU91532.2 - 0.00076 19.6 0.0 0.8 9.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EAU91532.2 - 0.00077 18.6 0.0 0.58 9.2 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EAU91532.2 - 0.0008 18.2 0.0 0.068 11.8 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus NB-ARC PF00931.17 EAU91532.2 - 0.002 17.0 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain KTI12 PF08433.5 EAU91532.2 - 0.0026 16.9 0.1 0.048 12.8 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF2075 PF09848.4 EAU91532.2 - 0.0036 16.3 0.0 2.4 7.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EAU91532.2 - 0.0047 16.6 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 1 NTPase Arch_ATPase PF01637.13 EAU91532.2 - 0.0058 16.3 0.0 5.3 6.6 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EAU91532.2 - 0.0063 16.5 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.22 EAU91532.2 - 0.0072 16.6 0.0 1.9 8.8 0.0 2.8 2 0 0 2 2 2 1 ABC transporter DUF815 PF05673.8 EAU91532.2 - 0.0079 15.1 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SKI PF01202.17 EAU91532.2 - 0.016 15.0 0.5 0.44 10.4 0.0 2.7 3 0 0 3 3 2 0 Shikimate kinase IstB_IS21 PF01695.12 EAU91532.2 - 0.019 14.3 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_31 PF13614.1 EAU91532.2 - 0.023 14.6 0.4 3.6 7.4 0.0 3.4 4 0 0 4 4 3 0 AAA domain APS_kinase PF01583.15 EAU91532.2 - 0.023 14.3 0.0 0.38 10.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.1 EAU91532.2 - 0.038 13.9 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EAU91532.2 - 0.043 13.7 0.1 0.17 11.8 0.0 2.0 3 0 0 3 3 1 0 Cytidylate kinase-like family FtsK_SpoIIIE PF01580.13 EAU91532.2 - 0.051 13.0 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EAU91532.2 - 0.063 12.7 0.4 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EAU91532.2 - 0.072 12.6 0.1 0.94 9.0 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.10 EAU91532.2 - 0.079 11.6 0.0 0.66 8.5 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EAU91532.2 - 0.1 12.0 0.1 0.58 9.5 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain Mito_carr PF00153.22 EAU91535.1 - 7.6e-53 176.2 2.0 1.8e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TBPIP PF07106.8 EAU91536.2 - 5.2e-42 143.2 3.0 6.5e-42 142.9 2.1 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Penicillinase_R PF03965.11 EAU91536.2 - 6.4e-05 23.0 0.6 0.00024 21.1 0.1 2.1 1 1 1 2 2 2 1 Penicillinase repressor Cast PF10174.4 EAU91536.2 - 0.00079 17.6 4.3 0.00084 17.5 3.0 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DivIC PF04977.10 EAU91536.2 - 0.0046 16.4 5.5 0.036 13.5 0.5 2.6 1 1 1 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 EAU91536.2 - 0.0079 16.1 11.1 0.041 13.8 2.0 2.8 2 1 1 3 3 2 1 bZIP transcription factor Reo_sigmaC PF04582.7 EAU91536.2 - 0.0082 15.3 0.6 0.011 14.9 0.4 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF2051 PF09738.4 EAU91536.2 - 0.0086 15.3 1.7 0.011 15.0 1.2 1.1 1 0 0 1 1 1 1 Double stranded RNA binding protein (DUF2051) Mnd1 PF03962.10 EAU91536.2 - 0.011 15.3 3.4 0.016 14.9 2.3 1.2 1 0 0 1 1 1 0 Mnd1 family HTH_IclR PF09339.5 EAU91536.2 - 0.013 15.0 0.0 0.041 13.4 0.0 1.9 2 0 0 2 2 1 0 IclR helix-turn-helix domain DUF972 PF06156.8 EAU91536.2 - 0.02 15.2 6.0 0.4 11.0 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Herpes_BLRF2 PF05812.7 EAU91536.2 - 0.029 14.1 7.9 0.2 11.4 0.5 2.4 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein TrmB PF01978.14 EAU91536.2 - 0.033 13.8 0.0 0.078 12.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB YlqD PF11068.3 EAU91536.2 - 0.042 13.8 6.4 0.57 10.2 0.9 2.3 1 1 1 2 2 2 0 YlqD protein CtIP_N PF10482.4 EAU91536.2 - 0.054 13.2 0.2 0.054 13.2 0.2 2.3 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain LPP PF04728.8 EAU91536.2 - 0.059 13.1 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Lipoprotein leucine-zipper HALZ PF02183.13 EAU91536.2 - 0.075 12.7 5.8 2.2 8.0 0.6 2.9 1 1 0 2 2 2 0 Homeobox associated leucine zipper Mod_r PF07200.8 EAU91536.2 - 0.081 12.8 6.1 0.3 10.9 0.4 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nnf1 PF03980.9 EAU91536.2 - 0.09 12.7 9.9 0.54 10.2 0.6 2.6 2 1 1 3 3 2 0 Nnf1 APG6 PF04111.7 EAU91536.2 - 0.11 11.5 5.1 0.15 11.0 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3708 PF12501.3 EAU91536.2 - 0.11 12.2 1.1 0.17 11.6 0.5 1.5 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Bacillus_HBL PF05791.6 EAU91536.2 - 0.12 11.7 4.8 0.19 11.0 2.8 1.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) RraB PF06877.6 EAU91536.2 - 0.12 13.0 0.7 0.27 11.9 0.5 1.6 1 0 0 1 1 1 0 Regulator of ribonuclease activity B Phage_GP20 PF06810.6 EAU91536.2 - 0.14 11.5 7.3 0.035 13.5 2.7 1.7 2 0 0 2 2 1 0 Phage minor structural protein GP20 FlxA PF14282.1 EAU91536.2 - 0.15 12.0 7.7 0.2 11.5 4.9 1.6 1 1 0 1 1 1 0 FlxA-like protein Med4 PF10018.4 EAU91536.2 - 0.15 11.4 5.4 0.54 9.6 3.7 1.9 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 bZIP_2 PF07716.10 EAU91536.2 - 0.2 11.5 10.2 1.3 8.8 0.2 3.0 3 0 0 3 3 2 0 Basic region leucine zipper FlaC_arch PF05377.6 EAU91536.2 - 0.34 10.8 5.4 2.2 8.2 0.4 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EAU91536.2 - 0.43 10.1 10.6 1.4 8.4 7.2 1.8 1 1 0 1 1 1 0 IncA protein Ax_dynein_light PF10211.4 EAU91536.2 - 0.44 10.3 6.8 2.5 7.8 3.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain ATG16 PF08614.6 EAU91536.2 - 0.48 10.2 11.1 0.24 11.1 4.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EAU91536.2 - 0.5 10.2 10.6 1.2 8.9 7.1 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 EAU91536.2 - 0.51 10.0 8.3 7.8 6.2 2.4 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF904 PF06005.7 EAU91536.2 - 0.52 10.6 16.7 26 5.2 11.6 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TMF_TATA_bd PF12325.3 EAU91536.2 - 0.58 9.9 10.5 0.96 9.1 6.0 2.2 1 1 2 3 3 2 0 TATA element modulatory factor 1 TATA binding CCDC-167 PF15188.1 EAU91536.2 - 0.62 10.0 5.0 2 8.3 3.3 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1192 PF06698.6 EAU91536.2 - 0.74 9.6 3.5 10 5.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.2 EAU91536.2 - 0.89 9.3 10.4 3.2 7.6 7.3 1.9 1 1 0 1 1 1 0 Tropomyosin like Cep57_MT_bd PF06657.8 EAU91536.2 - 0.94 9.4 6.0 0.82 9.6 2.6 2.1 2 1 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 Striatin PF08232.7 EAU91536.2 - 1 9.6 7.2 6.7 7.0 5.0 2.3 1 1 0 1 1 1 0 Striatin family ADIP PF11559.3 EAU91536.2 - 1.1 9.1 9.3 0.82 9.5 1.3 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MbeD_MobD PF04899.7 EAU91536.2 - 2 8.3 6.2 8.1 6.4 0.8 3.1 2 1 1 3 3 3 0 MbeD/MobD like Seryl_tRNA_N PF02403.17 EAU91536.2 - 2.2 8.3 6.9 3.4 7.7 3.9 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CENP-H PF05837.7 EAU91536.2 - 2.3 8.4 10.8 2.6 8.2 4.2 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) IFP_35_N PF07334.8 EAU91536.2 - 2.5 8.1 6.3 1.1 9.2 0.6 3.0 1 1 2 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TSC22 PF01166.13 EAU91536.2 - 3.4 7.7 8.6 5.4 7.0 0.8 2.7 1 1 1 2 2 2 0 TSC-22/dip/bun family CENP-Q PF13094.1 EAU91536.2 - 3.4 7.6 11.8 15 5.5 5.1 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GrpE PF01025.14 EAU91536.2 - 3.5 7.1 9.6 23 4.4 1.2 3.2 1 1 2 3 3 2 0 GrpE Wbp11 PF09429.5 EAU91536.2 - 3.7 7.5 6.4 12 5.9 0.7 2.8 1 1 1 2 2 2 0 WW domain binding protein 11 DUF2681 PF10883.3 EAU91536.2 - 4.2 7.6 7.3 0.62 10.3 1.0 2.3 2 1 1 3 3 2 0 Protein of unknown function (DUF2681) Rootletin PF15035.1 EAU91536.2 - 6.2 6.7 11.2 2.6 7.9 2.0 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Prefoldin_2 PF01920.15 EAU91536.2 - 6.6 6.5 12.5 0.66 9.7 2.5 3.0 2 1 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EAU91536.2 - 9.7 6.0 14.4 18 5.2 7.5 3.0 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Ras PF00071.17 EAU91537.2 - 2.3e-49 166.8 0.0 2.7e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU91537.2 - 9.7e-18 64.7 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU91537.2 - 1.6e-05 24.2 0.0 3.5e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 EAU91537.2 - 0.013 14.7 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-patch_2 PF12656.2 EAU91540.2 - 1.8e-27 95.0 0.0 9.3e-27 92.6 0.0 2.3 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 EAU91540.2 - 0.00025 20.7 0.9 0.00075 19.2 0.6 1.9 1 0 0 1 1 1 1 G-patch domain AA_permease PF00324.16 EAU91543.2 - 3.8e-81 272.8 37.7 3e-69 233.5 19.6 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EAU91543.2 - 6.1e-18 64.5 30.0 6.1e-18 64.5 20.8 2.0 1 1 1 2 2 2 1 Amino acid permease NTP_transferase PF00483.18 EAU91544.1 - 7.3e-42 143.3 0.0 1.3e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EAU91544.1 - 9e-08 32.3 0.1 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 EAU91544.1 - 0.0002 21.0 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 EAU91544.1 - 0.007 15.8 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF364 PF04016.7 EAU91544.1 - 0.03 13.6 0.0 0.068 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF364) G-alpha PF00503.15 EAU91545.2 - 3e-117 391.6 0.0 3.9e-117 391.2 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU91545.2 - 5.7e-06 25.6 0.0 0.096 11.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EAU91545.2 - 0.005 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EAU91545.2 - 0.1 11.9 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EAU91546.2 - 4.7e-08 33.4 0.3 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EAU91546.2 - 3.7e-05 24.5 0.2 7.1e-05 23.6 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU91546.2 - 0.0023 17.8 0.0 0.023 14.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain PRK PF00485.13 EAU91546.2 - 0.042 13.4 0.2 0.41 10.1 0.0 2.1 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EAU91546.2 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.19 EAU91547.1 - 8.5e-89 298.2 1.0 1.3e-88 297.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EAU91547.1 - 5.8e-23 80.4 0.0 1.8e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EAU91547.1 - 2.4e-14 53.0 0.2 5.6e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU91547.1 - 7.3e-11 41.9 0.1 5.5e-10 39.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU91547.1 - 1.2e-10 41.6 0.4 2.9e-07 30.5 0.2 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAU91547.1 - 4e-09 36.0 0.6 9.6e-09 34.8 0.4 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EAU91547.1 - 2.6e-06 26.7 0.5 6e-06 25.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EAU91547.1 - 3.6e-06 26.0 3.2 8.1e-05 21.6 0.3 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EAU91547.1 - 5.3e-06 26.6 0.2 1.9e-05 24.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU91547.1 - 7.4e-06 25.8 0.1 1.9e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EAU91547.1 - 3.3e-05 22.5 6.7 4.9e-05 21.9 0.5 2.9 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EAU91547.1 - 3.7e-05 22.9 1.4 0.0059 15.7 0.2 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 EAU91547.1 - 0.0011 19.3 0.3 0.024 15.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EAU91547.1 - 0.002 17.3 0.3 0.008 15.3 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EAU91547.1 - 0.0048 15.8 0.1 0.0074 15.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EAU91547.1 - 0.019 15.1 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EAU91547.1 - 0.031 13.8 0.2 0.057 12.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EAU91547.1 - 0.074 12.7 0.1 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M19 PF01244.16 EAU91548.2 - 8.1e-103 343.7 0.0 9.8e-103 343.4 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) G-alpha PF00503.15 EAU91549.1 - 1.5e-114 382.6 0.1 1.9e-114 382.3 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU91549.1 - 5.7e-09 35.4 0.5 9.2e-06 24.9 0.0 2.7 2 1 0 3 3 3 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 EAU91549.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EAU91549.1 - 0.037 13.4 0.0 2.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EAU91549.1 - 0.09 12.9 0.0 0.29 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain SAM_1 PF00536.25 EAU91550.1 - 0.00015 21.8 0.0 0.00061 19.9 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EAU91550.1 - 0.00047 19.9 0.0 0.0014 18.4 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) O-FucT PF10250.4 EAU91551.1 - 7.1e-14 51.6 0.3 2.1e-10 40.2 0.3 3.1 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Hydrolase_6 PF13344.1 EAU91552.2 - 2.1e-24 85.3 0.0 3.6e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU91552.2 - 5.3e-24 83.7 0.0 2.3e-23 81.6 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EAU91552.2 - 0.00017 21.8 0.0 0.013 15.7 0.0 2.6 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU91552.2 - 0.022 15.2 0.0 0.38 11.1 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Git3 PF11710.3 EAU91554.2 - 0.78 9.2 21.3 0.029 13.9 10.6 1.6 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EAU91554.2 - 3.8 6.3 15.2 0.2 10.5 4.2 2.4 1 1 0 2 2 2 0 Slime mold cyclic AMP receptor Fungal_trans PF04082.13 EAU91555.2 - 2e-07 30.1 0.1 3.3e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU91555.2 - 5.4e-06 26.2 11.9 9.2e-06 25.4 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PgaD PF13994.1 EAU91555.2 - 0.0051 16.2 0.1 0.0089 15.5 0.1 1.4 1 0 0 1 1 1 1 PgaD-like protein TPT PF03151.11 EAU91556.2 - 4.8e-29 100.9 8.7 4.8e-29 100.9 6.0 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EAU91556.2 - 1.5e-10 40.4 16.2 2.5e-10 39.7 11.1 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EAU91556.2 - 5.8e-09 36.0 29.6 6.6e-07 29.4 6.7 2.7 2 1 1 3 3 3 2 EamA-like transporter family DUF2721 PF11026.3 EAU91556.2 - 3 7.4 16.0 0.45 10.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1129 PF06570.6 EAU91556.2 - 5.1 6.3 12.0 4.2 6.6 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Med31 PF05669.7 EAU91557.1 - 1.3e-34 117.9 6.3 1.7e-34 117.6 4.4 1.1 1 0 0 1 1 1 1 SOH1 Peptidase_C12 PF01088.16 EAU91558.1 - 1.1e-52 178.3 0.0 2.5e-52 177.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RhoGAP PF00620.22 EAU91559.2 - 8e-29 100.2 0.0 1.5e-28 99.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 EAU91559.2 - 9.4e-28 96.4 0.0 1.9e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.21 EAU91559.2 - 4.3e-08 32.8 8.3 3.2e-06 26.8 3.2 2.5 2 0 0 2 2 2 2 WW domain p450 PF00067.17 EAU91561.1 - 1e-75 255.0 0.0 1.9e-75 254.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 ECH PF00378.15 EAU91562.1 - 5.5e-77 258.1 1.1 6.9e-77 257.8 0.8 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EAU91562.1 - 0.00058 19.9 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region YCII PF03795.9 EAU91563.2 - 8.2e-06 25.9 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.9 EAU91564.1 - 2.3e-09 37.3 0.0 2.9e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.9 EAU91565.1 - 2.9e-10 40.1 0.0 3.9e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain BTB PF00651.26 EAU91566.2 - 4.6e-06 26.5 0.0 8.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain GlutR_N PF05201.10 EAU91566.2 - 0.085 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain zf-C3HC4 PF00097.20 EAU91567.2 - 4.6e-07 29.3 2.4 4.6e-07 29.3 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU91567.2 - 1.5e-06 28.0 3.4 1.5e-06 28.0 2.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU91567.2 - 2.2e-06 27.2 5.9 7.6e-06 25.5 1.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EAU91567.2 - 5.3e-06 26.1 0.4 5.3e-06 26.1 0.3 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EAU91567.2 - 3.6e-05 23.3 0.8 0.00011 21.8 0.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EAU91567.2 - 0.00021 21.0 10.9 0.0011 18.7 7.5 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU91567.2 - 0.00032 20.5 2.9 0.00032 20.5 2.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING ADIP PF11559.3 EAU91567.2 - 0.00068 19.5 1.2 0.00092 19.1 0.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding zf-C3HC4_3 PF13920.1 EAU91567.2 - 0.00069 19.2 5.1 0.016 14.8 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF948 PF06103.6 EAU91567.2 - 0.0046 16.7 0.7 0.0074 16.1 0.5 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Myosin_tail_1 PF01576.14 EAU91567.2 - 0.0055 14.5 0.7 0.0068 14.1 0.5 1.0 1 0 0 1 1 1 1 Myosin tail TMF_TATA_bd PF12325.3 EAU91567.2 - 0.0099 15.6 0.4 0.016 14.9 0.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Herpes_BLRF2 PF05812.7 EAU91567.2 - 0.017 14.9 0.8 0.027 14.2 0.5 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TBPIP PF07106.8 EAU91567.2 - 0.02 14.4 0.7 0.029 13.9 0.5 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UPF0547 PF10571.4 EAU91567.2 - 0.021 14.5 2.4 0.61 9.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 IncA PF04156.9 EAU91567.2 - 0.022 14.3 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EAU91567.2 - 0.027 14.2 1.1 0.04 13.7 0.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Baculo_IE-1 PF05290.6 EAU91567.2 - 0.032 13.9 0.5 0.032 13.9 0.3 1.5 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) DUF2051 PF09738.4 EAU91567.2 - 0.037 13.3 0.3 0.049 12.9 0.2 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) ATG16 PF08614.6 EAU91567.2 - 0.045 13.5 1.7 0.081 12.7 1.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EAU91567.2 - 0.053 13.8 0.1 0.08 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) PspA_IM30 PF04012.7 EAU91567.2 - 0.054 12.8 1.2 0.079 12.3 0.9 1.2 1 0 0 1 1 1 0 PspA/IM30 family Striatin PF08232.7 EAU91567.2 - 0.069 13.4 0.5 0.1 12.9 0.3 1.2 1 0 0 1 1 1 0 Striatin family DivIC PF04977.10 EAU91567.2 - 0.071 12.6 2.2 0.11 11.9 1.5 1.2 1 0 0 1 1 1 0 Septum formation initiator Atg14 PF10186.4 EAU91567.2 - 0.091 11.6 0.8 0.14 11.0 0.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EAU91567.2 - 0.1 12.3 1.7 0.15 11.8 1.1 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prominin PF05478.6 EAU91567.2 - 0.12 9.8 0.6 0.15 9.5 0.4 1.1 1 0 0 1 1 1 0 Prominin zf-rbx1 PF12678.2 EAU91567.2 - 0.14 12.3 5.5 0.34 11.0 2.2 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger Cluap1 PF10234.4 EAU91567.2 - 0.15 11.2 2.8 0.2 10.8 1.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.6 EAU91567.2 - 0.16 10.6 2.4 0.21 10.1 1.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4446 PF14584.1 EAU91567.2 - 0.2 11.5 0.4 0.28 11.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF904 PF06005.7 EAU91567.2 - 0.26 11.5 2.5 0.47 10.7 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) zf-MIZ PF02891.15 EAU91567.2 - 0.27 10.7 6.6 1.5 8.3 1.5 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EAU91567.2 - 0.36 10.6 3.9 0.41 10.5 0.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 EAU91567.2 - 4.1 7.3 6.6 27 4.7 3.1 2.6 2 1 0 2 2 2 0 IBR domain FANCL_C PF11793.3 EAU91567.2 - 5.4 7.0 11.0 1.8 8.5 3.1 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain DUF221 PF02714.10 EAU91569.2 - 5e-64 216.2 17.7 8.5e-35 120.1 0.4 3.3 2 1 1 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EAU91569.2 - 1.3e-37 128.7 2.0 3.3e-37 127.4 1.4 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EAU91569.2 - 4.3e-18 65.6 2.7 4.3e-18 65.6 1.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EAU91569.2 - 9.4e-16 57.4 0.2 2.7e-15 55.9 0.2 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein HEAT PF02985.17 EAU91570.2 - 7.2e-10 38.1 0.7 0.059 13.4 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EAU91570.2 - 7.5e-07 29.3 0.0 0.0052 17.0 0.0 3.4 3 1 0 3 3 3 2 HEAT repeats Pkinase PF00069.20 EAU91570.2 - 1.2e-05 24.6 0.0 2.6e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 EAU91570.2 - 0.00036 20.9 1.6 0.25 11.8 0.0 4.6 3 2 1 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.15 EAU91570.2 - 0.02 13.2 0.0 2.6 6.2 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region Kinase-like PF14531.1 EAU91570.2 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Med14 PF08638.6 EAU91571.2 - 3.5e-41 140.5 0.0 6.8e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 DUF2360 PF10152.4 EAU91571.2 - 0.091 13.0 0.8 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) RPN7 PF10602.4 EAU91571.2 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 zf-RING_2 PF13639.1 EAU91572.1 - 0.0018 18.0 3.5 0.0037 17.0 2.4 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EAU91572.1 - 0.039 13.9 1.5 0.076 12.9 1.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Acetyltransf_1 PF00583.19 EAU91573.2 - 3e-10 39.9 0.0 1.1e-05 25.2 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family FR47 PF08445.5 EAU91573.2 - 5.9e-06 25.9 0.0 0.07 12.9 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 EAU91573.2 - 0.00057 20.0 0.0 0.0074 16.4 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EAU91573.2 - 0.0055 16.8 0.0 0.069 13.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAU91573.2 - 0.0057 16.7 0.0 0.11 12.7 0.0 2.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EAU91573.2 - 0.022 14.6 0.0 0.75 9.7 0.0 2.6 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase PEPCK_ATP PF01293.15 EAU91574.2 - 4e-194 645.4 0.0 1.5e-192 640.3 0.0 2.0 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EAU91574.2 - 0.002 17.5 0.0 0.0051 16.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EAU91574.2 - 0.067 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Amidohydro_2 PF04909.9 EAU91576.2 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Yae1_N PF09811.4 EAU91576.2 - 0.00059 19.3 14.2 0.036 13.5 9.8 2.8 1 1 0 1 1 1 1 Essential protein Yae1, N terminal APG6 PF04111.7 EAU91576.2 - 0.19 10.7 16.2 0.28 10.1 11.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Snf7 PF03357.16 EAU91576.2 - 6.5 6.0 12.6 2.1 7.6 5.0 2.1 2 0 0 2 2 2 0 Snf7 IncA PF04156.9 EAU91576.2 - 8.1 5.9 19.9 16 5.0 13.8 1.5 1 1 0 1 1 1 0 IncA protein CR6_interact PF10147.4 EAU91578.2 - 0.0045 16.3 10.2 0.0081 15.5 7.1 1.4 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3636 PF12331.3 EAU91578.2 - 0.04 13.4 0.1 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3636) Phage_Nu1 PF07471.7 EAU91578.2 - 0.27 10.7 4.2 0.43 10.0 2.4 1.7 1 1 0 1 1 1 0 Phage DNA packaging protein Nu1 Ada3 PF10198.4 EAU91578.2 - 0.27 10.9 9.2 0.54 10.0 6.4 1.5 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 L_lactis_ph-MCP PF06673.6 EAU91578.2 - 0.82 8.3 3.1 1.4 7.6 2.1 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF342 PF03961.8 EAU91578.2 - 4.9 5.4 7.5 7.2 4.9 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SNase PF00565.12 EAU91580.2 - 2.4e-60 201.5 0.1 7.9e-21 74.3 0.0 5.8 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EAU91580.2 - 2.3e-22 79.0 0.0 4.1e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Peptidase_S41 PF03572.13 EAU91581.2 - 4.5e-06 26.1 0.0 1.7e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 Peptidase family S41 HAD_2 PF13419.1 EAU91582.1 - 8.7e-20 71.6 0.0 1.1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU91582.1 - 2.3e-12 46.4 0.0 1.3e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EAU91582.1 - 7.2e-11 42.9 0.0 1.2e-10 42.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EAU91582.1 - 0.0047 16.8 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EAU91582.1 - 0.008 16.3 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_S6 PF01250.12 EAU91583.1 - 6.9e-09 35.4 0.0 8.2e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 AAA_17 PF13207.1 EAU91584.2 - 4.8e-05 24.1 0.1 9e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EAU91584.2 - 0.0024 16.9 0.0 0.0055 15.8 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EAU91584.2 - 0.004 17.4 0.1 0.024 14.9 0.0 2.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EAU91584.2 - 0.0061 16.5 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EAU91584.2 - 0.047 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 EAU91584.2 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 EAU91584.2 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EAU91584.2 - 0.089 12.8 0.1 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Rer1 PF03248.8 EAU91585.2 - 2.5e-78 261.6 2.2 2.9e-78 261.5 1.5 1.0 1 0 0 1 1 1 1 Rer1 family EI24 PF07264.6 EAU91585.2 - 0.0006 19.3 3.6 0.00078 18.9 2.5 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Polysacc_synt_3 PF13440.1 EAU91585.2 - 0.0063 16.0 1.7 1.4 8.2 0.3 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein DUF457 PF04307.9 EAU91585.2 - 0.24 10.7 2.1 3.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Vps55 PF04133.9 EAU91585.2 - 0.65 9.7 6.2 0.11 12.2 0.7 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 55 BNR PF02012.15 EAU91586.2 - 7.2e-09 34.1 37.4 0.22 11.4 0.6 10.5 10 0 0 10 10 10 8 BNR/Asp-box repeat UPF0029 PF01205.14 EAU91587.1 - 9.2e-22 76.8 0.0 1.5e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 IPP-2 PF04979.9 EAU91587.1 - 0.091 13.0 0.2 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) YlbD_coat PF14071.1 EAU91587.1 - 0.1 12.6 0.4 0.5 10.4 0.2 2.0 1 1 1 2 2 2 0 Putative coat protein TMF_TATA_bd PF12325.3 EAU91587.1 - 0.47 10.1 3.5 9.2 6.0 0.1 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CPSase_L_D2 PF02786.12 EAU91591.1 - 2.9e-97 324.0 0.0 1.3e-75 253.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EAU91591.1 - 6.1e-41 139.0 0.7 1.2e-40 138.0 0.5 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EAU91591.1 - 5.7e-36 123.9 0.2 1.4e-19 70.5 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EAU91591.1 - 8.5e-35 119.1 0.0 7.6e-18 64.6 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EAU91591.1 - 5.1e-18 64.9 0.0 3.7e-09 35.7 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EAU91591.1 - 6.6e-16 58.1 0.0 1.1e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EAU91591.1 - 4.7e-12 45.7 0.1 8.4e-05 22.0 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EAU91591.1 - 2.7e-06 27.3 0.0 0.0067 16.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 EAU91591.1 - 1.5e-05 24.3 0.1 0.021 14.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EAU91591.1 - 1.8e-05 24.3 0.0 0.037 13.5 0.0 3.0 3 0 0 3 3 3 2 RimK-like ATP-grasp domain MGS PF02142.17 EAU91591.1 - 0.0028 17.5 0.0 0.015 15.2 0.0 2.4 1 1 0 1 1 1 1 MGS-like domain Epimerase PF01370.16 EAU91591.1 - 0.064 12.6 0.0 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNase_T PF00929.19 EAU91593.1 - 2e-24 86.7 0.0 2.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease PPTA PF01239.17 EAU91594.1 - 2.8e-06 26.4 12.4 0.03 13.6 0.4 4.9 6 0 0 6 6 6 3 Protein prenyltransferase alpha subunit repeat V-SNARE_C PF12352.3 EAU91598.2 - 2.7e-15 56.1 0.3 7.4e-15 54.7 0.2 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EAU91598.2 - 2.4e-05 23.9 0.3 9.8e-05 21.9 0.0 1.9 2 1 0 2 2 2 1 Sec20 FUSC PF04632.7 EAU91598.2 - 0.01 14.2 0.1 0.015 13.7 0.1 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF745 PF05335.8 EAU91598.2 - 0.031 13.8 5.3 0.026 14.0 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Nop25 PF09805.4 EAU91599.1 - 1.2e-20 73.9 30.1 1.2e-20 73.9 20.9 2.8 2 2 0 2 2 2 1 Nucleolar protein 12 (25kDa) FAM72 PF14976.1 EAU91600.2 - 1.7e-12 47.4 6.6 7.8e-11 42.0 4.6 2.1 1 1 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.9 EAU91600.2 - 0.02 14.9 2.3 0.02 14.9 1.6 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly E7 PF00527.13 EAU91600.2 - 2.5 8.3 8.4 68 3.7 5.8 2.3 1 1 0 1 1 1 0 E7 protein, Early protein ubiquitin PF00240.18 EAU91601.1 - 2.9e-137 446.2 22.0 5.2e-34 115.4 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EAU91601.1 - 7.8e-78 256.1 21.3 5.6e-19 67.6 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAU91601.1 - 2.1e-24 85.5 10.0 0.00016 21.8 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAU91601.1 - 2.8e-21 75.8 0.6 0.0017 18.0 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAU91601.1 - 4.9e-14 52.1 3.1 0.12 12.3 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAU91601.1 - 9e-14 51.4 1.9 0.11 12.6 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EAU91601.1 - 1.3e-10 41.2 0.0 1.5 8.8 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EAU91601.1 - 4.4e-07 29.5 5.1 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EAU91601.1 - 1.2e-06 27.8 0.7 1 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 EAU91601.1 - 5.4e-06 26.2 5.3 6.4 6.7 0.0 4.2 4 0 0 4 4 4 3 GLUT4 regulating protein TUG Big_3_3 PF13750.1 EAU91601.1 - 0.00051 19.5 0.0 18 4.6 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EAU91601.1 - 0.001 19.3 1.0 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Plexin_cytopl PF08337.7 EAU91601.1 - 0.0035 15.7 13.4 3.7 5.7 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 EAU91601.1 - 0.012 15.7 5.4 56 3.9 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EAU91601.1 - 0.026 14.4 14.7 6.7 6.6 0.3 4.6 1 1 3 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EAU91601.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EAU91601.1 - 0.048 13.6 7.2 47 4.0 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EAU91601.1 - 1.3 9.1 13.1 57 3.8 0.2 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EAU91601.1 - 1.8 8.5 7.2 1.2e+02 2.7 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 EAU91601.1 - 5.3 6.7 13.3 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 SET PF00856.23 EAU91602.1 - 1.2e-09 38.6 0.1 1.2e-09 38.6 0.1 3.8 2 2 0 2 2 2 1 SET domain Nucleoplasmin PF03066.10 EAU91602.1 - 0.018 14.5 0.6 0.018 14.5 0.4 3.9 3 1 0 3 3 3 0 Nucleoplasmin Cpn60_TCP1 PF00118.19 EAU91603.1 - 7.2e-151 503.0 0.0 9.4e-151 502.7 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA_22 PF13401.1 EAU91606.1 - 0.033 14.3 0.3 4.7 7.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain PAX PF00292.13 EAU91606.1 - 0.11 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain PHO4 PF01384.15 EAU91607.2 - 2.5e-101 338.5 13.7 3.1e-101 338.2 9.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family Drf_GBD PF06371.8 EAU91607.2 - 0.2 11.0 0.2 0.54 9.5 0.0 1.8 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Acetyltransf_3 PF13302.1 EAU91609.1 - 1e-13 51.6 0.0 1.6e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU91609.1 - 8.7e-07 28.8 0.0 1.5e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EAU91609.1 - 0.00055 19.8 0.0 0.0059 16.4 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU91609.1 - 0.00099 19.0 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Arrestin_C PF02752.17 EAU91611.1 - 3e-13 50.0 0.0 1.3e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EAU91611.1 - 8.3e-10 38.6 0.0 5.4e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Tim17 PF02466.14 EAU91612.2 - 8e-33 113.2 10.5 1e-32 112.8 7.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 EAU91612.2 - 0.053 13.4 0.6 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Glyco_hydro_16 PF00722.16 EAU91614.2 - 2.5e-07 30.1 0.0 5.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TrkH PF02386.11 EAU91616.2 - 8.7e-98 327.1 11.3 1.2e-93 313.5 4.6 2.1 2 0 0 2 2 2 2 Cation transport protein MIF4G PF02854.14 EAU91617.1 - 5.2e-59 199.1 0.6 1.3e-58 197.9 0.2 1.9 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 EAU91617.1 - 8.1e-17 60.8 0.0 4.7e-16 58.4 0.0 2.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 EAU91617.1 - 9e-09 35.0 0.2 3.5e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 MA3 domain AAA_16 PF13191.1 EAU91618.2 - 0.0039 17.2 0.6 0.013 15.4 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EAU91618.2 - 0.069 12.6 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DRAT PF07357.6 EAU91618.2 - 0.11 11.6 0.0 0.97 8.5 0.0 2.0 2 0 0 2 2 2 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) zf-CCCH_2 PF14608.1 EAU91619.2 - 1.3e-09 37.6 33.4 0.00067 19.5 2.6 4.3 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type DUF3086 PF11285.3 EAU91619.2 - 0.26 10.0 0.9 0.46 9.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) M PF02370.11 EAU91619.2 - 1.5 9.4 8.0 4.2 8.0 5.5 1.8 1 0 0 1 1 1 0 M protein repeat zf-C3H1 PF10650.4 EAU91619.2 - 5.4 6.5 14.8 7 6.2 0.6 3.7 4 0 0 4 4 4 0 Putative zinc-finger domain Cyclin_N PF00134.18 EAU91620.2 - 1.7e-10 40.5 0.0 2.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EAU91620.2 - 5.8e-08 33.2 0.0 8.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin Ribosomal_S5 PF00333.15 EAU91621.1 - 2.4e-28 97.6 1.3 5.7e-28 96.4 0.9 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EAU91621.1 - 2.1e-21 74.9 0.0 3.4e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ODC_AZ PF02100.12 EAU91622.2 - 9.3e-18 63.7 0.0 1.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1771 PF08590.5 EAU91623.1 - 1.8e-21 75.8 7.0 4.3e-21 74.6 4.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EAU91623.1 - 4.1e-15 55.7 0.2 1e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 Smr domain DUF4407 PF14362.1 EAU91623.1 - 0.053 12.4 1.1 0.064 12.2 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.13 EAU91623.1 - 0.23 11.2 4.7 0.18 11.6 1.5 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) PspA_IM30 PF04012.7 EAU91623.1 - 1.5 8.0 5.4 0.29 10.4 1.3 1.5 2 0 0 2 2 2 0 PspA/IM30 family PAT1 PF09770.4 EAU91623.1 - 1.9 6.6 10.3 2.5 6.2 7.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Afi1 PF07792.7 EAU91626.1 - 8.6e-35 119.8 0.0 2.2e-34 118.5 0.0 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EAU91626.1 - 5.1e-34 116.3 0.0 1e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EAU91626.1 - 0.0009 17.8 0.0 1.7 7.0 0.0 3.1 2 1 1 3 3 3 2 Transport protein Avl9 Fungal_trans PF04082.13 EAU91627.1 - 2e-09 36.7 0.1 3.1e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU91627.1 - 0.11 12.3 9.7 0.22 11.4 6.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Paralemmin PF03285.10 EAU91627.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Paralemmin Sigma_1_2 PF03084.9 EAU91628.1 - 0.029 13.0 0.1 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family CI-B14_5a PF07347.7 EAU91628.1 - 0.059 13.1 0.2 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) G_glu_transpept PF01019.16 EAU91631.2 - 2e-146 488.5 0.0 2.6e-146 488.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.13 EAU91632.1 - 2.9e-30 105.4 1.9 4.1e-30 104.9 1.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EAU91632.1 - 1.8e-13 49.9 14.5 6.2e-13 48.1 10.0 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 EAU91632.1 - 0.00011 22.5 0.0 0.00036 20.9 0.0 1.9 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EAU91632.1 - 0.00032 19.6 0.0 0.0008 18.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Toxin_7 PF05980.7 EAU91632.1 - 0.75 9.8 3.1 1.4 8.9 2.2 1.4 1 0 0 1 1 1 0 Toxin 7 Acyltransferase PF01553.16 EAU91635.2 - 3.8e-10 39.3 0.0 2.3e-09 36.8 0.0 2.0 1 1 1 2 2 2 1 Acyltransferase CobD_Cbib PF03186.8 EAU91635.2 - 0.065 12.3 0.3 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 CobD/Cbib protein Pkinase PF00069.20 EAU91637.1 - 3.4e-71 239.4 0.0 4.4e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91637.1 - 2e-38 131.9 0.0 2.6e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EAU91637.1 - 3.2e-17 62.4 0.6 5.6e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EAU91637.1 - 1.4e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU91637.1 - 0.00037 19.5 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU91637.1 - 0.0076 16.0 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family S-methyl_trans PF02574.11 EAU91638.1 - 1.4e-30 106.6 0.0 2.6e-16 59.8 0.0 2.1 1 1 1 2 2 2 2 Homocysteine S-methyltransferase Cytochrom_B561 PF03188.11 EAU91639.2 - 4.8e-13 49.1 3.3 7.6e-13 48.4 2.3 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EAU91639.2 - 5e-06 26.4 0.1 1.3e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 DOMON domain Cytochrom_B_N PF00033.14 EAU91639.2 - 5.8e-05 22.5 5.1 5.8e-05 22.5 3.5 1.7 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB DUF2427 PF10348.4 EAU91639.2 - 0.0001 21.8 2.7 0.00025 20.5 1.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.1 EAU91639.2 - 0.0041 17.1 7.7 0.017 15.1 5.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DUF4181 PF13789.1 EAU91639.2 - 0.013 15.4 0.3 0.037 13.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) DUF2306 PF10067.4 EAU91639.2 - 0.022 14.8 0.1 0.022 14.8 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) Tetraspannin PF00335.15 EAU91639.2 - 0.2 10.8 9.0 0.51 9.5 4.0 2.2 2 0 0 2 2 2 0 Tetraspanin family DUF998 PF06197.8 EAU91639.2 - 0.96 8.7 16.7 0.85 8.9 6.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF998) DUF202 PF02656.10 EAU91639.2 - 3.4 7.9 5.6 8.7 6.6 0.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) API5 PF05918.6 EAU91640.2 - 9.4e-14 50.8 0.1 1.3e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 EAU91640.2 - 2.3e-07 31.0 0.5 5.1e-06 26.6 0.1 3.2 3 1 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 EAU91640.2 - 0.026 12.8 0.2 0.051 11.9 0.1 1.5 1 0 0 1 1 1 0 Adaptin N terminal region HEAT PF02985.17 EAU91640.2 - 0.027 14.5 0.3 12 6.3 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Stanniocalcin PF03298.8 EAU91640.2 - 0.032 13.2 0.2 0.055 12.4 0.1 1.3 1 0 0 1 1 1 0 Stanniocalcin family DUF2388 PF09498.5 EAU91640.2 - 0.066 12.8 0.0 0.65 9.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) MmgE_PrpD PF03972.9 EAU91641.2 - 5.2e-161 535.7 0.0 6.6e-161 535.4 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family PI3_PI4_kinase PF00454.22 EAU91644.2 - 3.4e-26 92.1 0.0 5e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.17 EAU91645.1 - 1.1e-12 47.3 0.1 2.3e-06 27.1 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU91645.1 - 1.9e-10 40.5 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU91645.1 - 1.7e-06 27.7 0.1 1.2e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU91645.1 - 0.043 13.5 0.0 8.5 6.2 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EAU91645.1 - 0.085 12.6 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.20 EAU91647.2 - 5e-49 166.7 0.0 2.1e-35 122.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91647.2 - 1.1e-17 64.0 0.0 1.3e-16 60.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU91647.2 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU91647.2 - 0.0047 15.9 0.0 0.0074 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU91647.2 - 0.089 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mnd1 PF03962.10 EAU91651.2 - 5.2e-33 114.3 3.0 5.7e-33 114.1 2.1 1.0 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 EAU91651.2 - 0.034 13.7 3.0 0.045 13.3 2.0 1.2 1 0 0 1 1 1 0 IncA protein T2SM PF04612.7 EAU91651.2 - 0.08 12.7 2.0 0.11 12.2 1.4 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Ax_dynein_light PF10211.4 EAU91651.2 - 0.087 12.6 4.2 0.13 12.1 2.9 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DivIC PF04977.10 EAU91651.2 - 0.11 11.9 10.7 0.12 11.8 2.0 2.3 1 1 1 2 2 2 0 Septum formation initiator Phage_int_SAM_5 PF13102.1 EAU91651.2 - 0.33 10.9 2.7 0.46 10.4 1.8 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain Ribosomal_L29 PF00831.18 EAU91651.2 - 0.42 10.3 4.5 0.22 11.2 0.3 2.1 2 0 0 2 2 2 0 Ribosomal L29 protein NYD-SP28_assoc PF14775.1 EAU91651.2 - 0.53 10.0 4.4 1.2 8.9 0.2 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF4140 PF13600.1 EAU91651.2 - 1.5 9.2 5.2 3.1 8.2 3.6 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 EAU91651.2 - 2.5 8.4 10.3 0.71 10.2 5.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EAU91651.2 - 5 7.5 6.2 11 6.3 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIVA PF05103.8 EAU91651.2 - 9.2 6.3 14.1 12 5.9 5.7 2.6 1 1 1 2 2 2 0 DivIVA protein zf-MYND PF01753.13 EAU91652.2 - 0.03 14.1 8.5 0.061 13.2 5.9 1.5 1 0 0 1 1 1 0 MYND finger Orn_Arg_deC_N PF02784.11 EAU91652.2 - 0.09 11.9 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Fungal_trans PF04082.13 EAU91653.1 - 5.5e-09 35.2 0.0 1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EAU91653.1 - 2.8e-07 30.3 13.6 4.6e-07 29.6 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vac_Fusion PF02346.11 EAU91653.1 - 0.084 12.3 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus fusion protein W2 PF02020.13 EAU91654.2 - 1e-20 73.4 0.5 1e-20 73.4 0.4 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PP2C PF00481.16 EAU91655.2 - 5.2e-66 222.6 1.3 3.2e-50 170.8 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EAU91655.2 - 0.0001 22.0 0.8 0.0006 19.5 0.4 2.2 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) UPF0029 PF01205.14 EAU91655.2 - 0.052 13.2 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 Choline_transpo PF04515.7 EAU91656.1 - 6.1e-91 304.6 13.0 6.1e-91 304.6 9.0 2.0 1 1 1 2 2 2 1 Plasma-membrane choline transporter Amastin PF07344.6 EAU91657.1 - 0.014 15.0 3.4 0.019 14.5 0.3 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein SUR7 PF06687.7 EAU91657.1 - 0.15 11.6 2.6 9.7 5.6 0.0 2.9 3 0 0 3 3 3 0 SUR7/PalI family CcmD PF04995.9 EAU91657.1 - 5.1 6.9 17.5 3 7.6 1.8 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Cellulase PF00150.13 EAU91658.1 - 9.7e-10 38.1 1.6 1.2e-09 37.7 1.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EAU91658.1 - 0.049 12.7 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Cellulase-like PF12876.2 EAU91658.1 - 0.053 13.9 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Sugar-binding cellulase-like FUSC_2 PF13515.1 EAU91659.2 - 1.1e-19 70.6 11.7 1.1e-19 70.6 8.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EAU91659.2 - 3.4e-13 48.9 23.7 5.7e-12 44.8 7.8 4.2 4 0 0 4 4 4 3 Fusaric acid resistance protein family DUF2421 PF10334.4 EAU91659.2 - 2.9e-11 43.4 0.2 5.7e-10 39.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EAU91659.2 - 2.5e-09 36.2 9.9 4.3e-08 32.2 2.3 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF939 PF06081.6 EAU91659.2 - 0.0027 17.5 1.9 0.0027 17.5 1.3 3.3 3 1 0 3 3 3 1 Bacterial protein of unknown function (DUF939) Ribosomal_S8e PF01201.17 EAU91660.1 - 2.4e-51 173.3 0.5 3e-51 172.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-RING_2 PF13639.1 EAU91661.2 - 0.0019 18.0 0.2 0.57 10.0 0.0 2.4 2 0 0 2 2 2 2 Ring finger domain Atg14 PF10186.4 EAU91662.2 - 0.013 14.4 7.0 0.025 13.5 4.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EAU91662.2 - 4.3 5.6 8.2 6.4 5.0 5.7 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EAU91663.2 - 1.5e-21 76.7 0.0 2.6e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAU91663.2 - 1.1e-16 60.8 0.3 3.7e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAU91663.2 - 8.7e-09 35.3 0.7 8.7e-09 35.3 0.5 3.1 3 1 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EAU91663.2 - 0.00058 19.4 0.1 0.0019 17.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EAU91663.2 - 0.048 13.1 0.7 2.1 7.8 0.1 2.9 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EAU91663.2 - 0.08 12.9 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase FLILHELTA PF10306.4 EAU91664.2 - 1.3e-08 34.7 0.0 2.2e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EAU91664.2 - 0.0071 16.6 0.0 0.013 15.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L35Ae PF01247.13 EAU91666.1 - 3.4e-43 145.3 0.8 3.8e-43 145.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EAU91666.1 - 0.0036 17.1 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Acyl-CoA_dh_N PF02771.11 EAU91667.1 - 4.8e-28 97.9 0.0 9.5e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EAU91667.1 - 1.2e-26 93.6 0.4 3.6e-26 92.0 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EAU91667.1 - 2.9e-21 74.7 0.2 2e-20 72.0 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EAU91667.1 - 2.7e-06 27.6 0.5 6.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain bZIP_1 PF00170.16 EAU91668.2 - 2.2e-05 24.3 4.9 5.1e-05 23.1 3.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAU91668.2 - 0.0048 16.6 4.9 0.0084 15.9 3.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper HAP1_N PF04849.8 EAU91668.2 - 0.032 13.1 0.2 0.051 12.5 0.1 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region TSC22 PF01166.13 EAU91668.2 - 0.04 13.8 0.8 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Sds3 PF08598.6 EAU91668.2 - 0.059 12.8 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Sds3-like KIAA1430 PF13879.1 EAU91668.2 - 0.065 13.6 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 KIAA1430 homologue Kinetocho_Slk19 PF12709.2 EAU91668.2 - 0.088 12.9 0.4 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Central kinetochore-associated DNA_pol_B_palm PF14792.1 EAU91669.2 - 1.8e-17 63.4 0.0 8.9e-17 61.1 0.0 2.1 2 1 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EAU91669.2 - 2.7e-09 36.4 0.0 5.8e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EAU91669.2 - 2.1e-07 30.4 0.0 4.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EAU91669.2 - 0.00014 21.9 0.0 0.00078 19.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain CTP_transf_2 PF01467.21 EAU91670.2 - 2.3e-26 92.7 0.0 3.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase MFS_1 PF07690.11 EAU91671.2 - 0.0027 16.4 3.9 0.0027 16.4 2.7 2.2 2 1 1 3 3 3 1 Major Facilitator Superfamily DUF805 PF05656.9 EAU91671.2 - 0.23 11.3 3.0 1.2 9.0 2.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) MFS_1 PF07690.11 EAU91672.2 - 3.8e-37 127.8 20.4 5.7e-37 127.2 14.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.14 EAU91672.2 - 7.5 5.9 8.5 1.9 7.9 0.2 3.0 2 1 1 3 3 3 0 VIT family MerC PF03203.9 EAU91672.2 - 7.9 6.8 10.3 9.3 6.6 1.0 3.8 2 2 0 2 2 2 0 MerC mercury resistance protein DUF601 PF04642.7 EAU91673.2 - 0.0055 16.1 4.4 0.0055 16.1 3.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF601 HlyD PF00529.15 EAU91673.2 - 0.0095 15.2 8.2 0.014 14.6 5.7 1.2 1 0 0 1 1 1 1 HlyD family secretion protein bZIP_1 PF00170.16 EAU91673.2 - 0.06 13.3 16.7 0.16 11.9 9.8 2.3 1 1 1 2 2 2 0 bZIP transcription factor DUF3138 PF11336.3 EAU91673.2 - 0.12 10.4 0.6 0.23 9.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF904 PF06005.7 EAU91673.2 - 3.4 8.0 6.5 5.4 7.3 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EAU91673.2 - 4.7 7.1 20.3 0.9 9.4 7.5 2.7 2 1 0 2 2 2 0 Basic region leucine zipper MaoC_dehydrat_N PF13452.1 EAU91690.2 - 0.063 13.0 0.0 12 5.7 0.0 2.4 2 1 0 2 2 2 0 N-terminal half of MaoC dehydratase FAM209 PF15206.1 EAU91691.2 - 0.0011 18.7 0.0 0.0013 18.5 0.0 1.1 1 0 0 1 1 1 1 FAM209 family FUSC-like PF12805.2 EAU91691.2 - 0.004 16.1 1.1 0.005 15.8 0.8 1.1 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS DivIC PF04977.10 EAU91691.2 - 0.0058 16.0 2.9 0.0058 16.0 2.0 1.6 2 1 0 2 2 2 1 Septum formation initiator Nop25 PF09805.4 EAU91691.2 - 0.025 14.6 3.4 0.04 13.9 2.4 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) IncA PF04156.9 EAU91691.2 - 0.13 11.8 6.4 0.17 11.4 4.4 1.2 1 0 0 1 1 1 0 IncA protein DUF883 PF05957.8 EAU91691.2 - 0.14 12.5 6.6 0.68 10.3 2.9 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4201 PF13870.1 EAU91691.2 - 0.17 11.3 7.8 0.29 10.5 5.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF972 PF06156.8 EAU91691.2 - 0.28 11.5 4.0 0.54 10.6 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF2229 PF09989.4 EAU91691.2 - 0.33 10.3 1.7 0.42 10.0 1.2 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DivIVA PF05103.8 EAU91691.2 - 0.53 10.3 5.7 0.21 11.6 0.9 2.0 1 1 1 2 2 2 0 DivIVA protein Kri1 PF05178.7 EAU91691.2 - 0.7 10.2 6.0 2 8.7 4.2 1.7 1 1 0 1 1 1 0 KRI1-like family Med21 PF11221.3 EAU91691.2 - 0.91 9.4 6.2 0.67 9.9 3.1 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Spectrin PF00435.16 EAU91691.2 - 1.1 9.6 5.5 6.3 7.1 0.1 2.1 1 1 1 2 2 2 0 Spectrin repeat TMF_DNA_bd PF12329.3 EAU91691.2 - 1.9 8.3 6.4 5.1 6.9 4.5 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4404 PF14357.1 EAU91691.2 - 2.3 8.6 4.7 7.9 6.9 0.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) IATP PF04568.7 EAU91691.2 - 2.7 8.0 6.8 0.56 10.2 2.1 1.8 2 1 0 2 2 1 0 Mitochondrial ATPase inhibitor, IATP F-box PF00646.28 EAU91692.1 - 0.036 13.7 1.3 0.089 12.4 0.1 2.2 2 0 0 2 2 2 0 F-box domain DEAD PF00270.24 EAU91695.2 - 5.5e-14 52.0 0.0 1.1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU91695.2 - 1.7e-09 37.4 0.0 5.3e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU91695.2 - 0.0018 18.1 0.0 0.0052 16.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAU91697.2 - 9.8e-71 237.9 0.2 1.6e-70 237.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU91697.2 - 2.6e-06 27.1 0.2 3.9e-05 23.4 0.1 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU91697.2 - 7.4e-06 25.9 0.0 2.2e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAU91697.2 - 0.00015 21.2 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EAU91697.2 - 0.00068 18.5 0.0 0.15 10.8 0.0 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Flavi_DEAD PF07652.9 EAU91697.2 - 0.069 12.9 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 Flavivirus DEAD domain Pkinase PF00069.20 EAU91698.2 - 6.6e-71 238.5 0.0 7.8e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU91698.2 - 1.2e-36 126.0 0.0 1.7e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAU91698.2 - 0.026 13.5 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU91698.2 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SET PF00856.23 EAU91699.2 - 0.015 15.5 1.9 0.042 14.1 1.3 1.7 1 1 0 1 1 1 0 SET domain Spindle_Spc25 PF08234.7 EAU91699.2 - 0.13 12.2 0.1 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 FR47 PF08445.5 EAU91701.2 - 2.2e-09 36.9 0.0 4.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EAU91701.2 - 3.4e-09 36.6 0.0 7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAU91701.2 - 0.00011 22.2 0.0 0.00031 20.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EAU91701.2 - 0.00037 20.5 0.0 0.0063 16.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EAU91701.2 - 0.0049 16.7 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EAU91701.2 - 0.12 12.0 0.7 3.6 7.3 0.0 2.3 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Peptidase_S8 PF00082.17 EAU91702.1 - 1.4e-51 175.3 10.2 2.3e-51 174.5 7.1 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAU91702.1 - 1e-15 58.0 0.0 2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 3HCDH_N PF02737.13 EAU91705.2 - 6.9e-50 169.1 1.7 3.2e-49 167.0 1.2 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EAU91705.2 - 1.5e-33 115.0 0.0 2.8e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EAU91705.2 - 5.4e-05 23.0 0.2 0.00011 22.0 0.2 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EAU91705.2 - 0.004 16.9 0.2 0.012 15.3 0.1 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EAU91705.2 - 0.067 12.3 0.1 0.24 10.5 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain COesterase PF00135.23 EAU91706.1 - 1.6e-86 291.1 0.0 2.2e-78 264.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU91706.1 - 4.4e-08 32.9 0.0 7.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU91706.1 - 0.004 16.9 0.1 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU91706.1 - 0.019 14.8 0.1 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 EAU91706.1 - 0.027 13.7 0.2 0.052 12.7 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EAU91706.1 - 0.031 13.8 0.1 0.1 12.1 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold F-box-like PF12937.2 EAU91707.2 - 1.6e-10 40.5 0.3 8.5e-10 38.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU91707.2 - 0.05 13.2 0.4 13 5.5 0.1 3.1 2 0 0 2 2 2 0 F-box domain PRTP PF01366.13 EAU91707.2 - 0.17 9.8 0.0 0.25 9.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein F-box-like PF12937.2 EAU91708.2 - 6.4e-06 25.7 0.2 1.3e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF1771 PF08590.5 EAU91709.2 - 0.25 11.3 7.2 0.56 10.2 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) SNF2_N PF00176.18 EAU91710.2 - 3.5e-68 229.5 0.2 6e-68 228.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EAU91710.2 - 4.1e-26 91.1 1.4 8.1e-26 90.1 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EAU91710.2 - 1.7e-18 65.9 2.2 5.1e-11 42.0 0.0 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EAU91710.2 - 4.4e-14 52.1 0.0 9.6e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TBP PF00352.16 EAU91710.2 - 0.0031 16.8 0.0 0.0073 15.6 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) Tfb4 PF03850.9 EAU91711.2 - 7.4e-50 169.7 0.0 9.3e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EAU91711.2 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain SPDY PF03771.11 EAU91711.2 - 0.056 12.9 0.3 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Asparaginase_2 PF01112.13 EAU91712.2 - 3.7e-43 147.4 0.2 5.2e-43 146.9 0.2 1.2 1 0 0 1 1 1 1 Asparaginase IF-2B PF01008.12 EAU91713.2 - 6.3e-54 182.8 0.0 8.4e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Abhydrolase_3 PF07859.8 EAU91714.1 - 3.6e-30 105.1 0.0 6.4e-22 78.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU91714.1 - 0.022 13.4 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) zf-C2H2 PF00096.21 EAU91715.2 - 8.9e-05 22.6 16.3 0.0013 18.9 0.2 3.5 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU91715.2 - 0.00014 21.9 11.0 0.072 13.4 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU91715.2 - 0.00066 19.8 0.3 0.00066 19.8 0.2 4.0 3 2 1 4 4 4 1 Zinc-finger double domain DUF2894 PF11445.3 EAU91715.2 - 0.02 15.1 10.5 0.049 13.9 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) zf-C2H2_2 PF12756.2 EAU91715.2 - 0.15 12.1 2.3 0.34 11.0 1.6 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EAU91715.2 - 0.33 10.7 3.5 0.72 9.6 2.5 1.5 1 0 0 1 1 1 0 BED zinc finger Rtf2 PF04641.7 EAU91715.2 - 2.8 7.0 15.4 14 4.7 10.7 1.8 1 1 0 1 1 1 0 Rtf2 RING-finger IBR PF01485.16 EAU91715.2 - 3.5 7.5 9.0 58 3.6 6.2 2.3 1 1 0 1 1 1 0 IBR domain DUF4557 PF15101.1 EAU91715.2 - 4.6 7.0 10.8 8 6.2 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) zf-met PF12874.2 EAU91715.2 - 7.4 6.9 6.9 1.5 9.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type TPR_11 PF13414.1 EAU91716.1 - 2.1e-22 78.5 8.1 5.6e-12 45.1 0.9 3.8 2 2 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 EAU91716.1 - 3.8e-22 76.9 6.4 3.7e-06 26.3 0.2 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EAU91716.1 - 3.1e-18 64.1 10.3 0.00026 20.6 0.2 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EAU91716.1 - 6.2e-16 57.1 13.0 0.00034 20.5 0.5 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EAU91716.1 - 2.8e-13 49.2 10.6 0.00037 20.8 0.0 6.1 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAU91716.1 - 2.9e-12 46.3 10.1 2.1e-07 30.7 0.3 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EAU91716.1 - 2.8e-11 43.6 15.4 1.6e-08 34.7 0.7 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU91716.1 - 1.8e-10 39.8 3.3 0.0063 16.2 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU91716.1 - 1.2e-09 38.5 7.6 3.9e-07 30.5 0.2 4.4 3 2 1 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EAU91716.1 - 1e-06 28.7 3.7 0.00027 21.0 0.9 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EAU91716.1 - 1.6e-06 27.8 3.5 0.018 14.8 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 EAU91716.1 - 8.4e-05 22.6 9.8 0.54 10.4 0.3 5.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAU91716.1 - 0.00022 20.7 6.6 0.67 9.8 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EAU91716.1 - 0.017 15.0 14.8 0.74 9.8 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EAU91716.1 - 0.059 13.2 2.2 0.94 9.4 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EAU91716.1 - 0.086 12.7 1.6 2.4 8.1 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EAU91716.1 - 0.14 12.6 4.4 72 4.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Tim17 PF02466.14 EAU91717.1 - 8.5e-31 106.6 5.7 1.1e-30 106.3 4.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-4CXXC_R1 PF10497.4 EAU91718.2 - 0.00015 21.8 2.3 0.00033 20.7 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF3782 PF12644.2 EAU91718.2 - 0.028 14.2 1.2 0.25 11.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Methyltransf_26 PF13659.1 EAU91719.1 - 7.1e-13 48.6 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EAU91719.1 - 3.4e-12 46.3 0.0 5.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 EAU91719.1 - 0.0024 17.4 0.0 2.4 7.5 0.0 2.6 2 1 0 2 2 2 2 DNA methylase zf-MYND PF01753.13 EAU91720.1 - 0.17 11.7 3.8 0.1 12.4 1.2 1.8 2 0 0 2 2 2 0 MYND finger zf-MYND PF01753.13 EAU91721.2 - 2.1e-06 27.5 10.5 2.1e-06 27.5 7.2 1.8 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.13 EAU91722.2 - 1.2e-09 37.9 17.0 2.6e-09 36.7 11.8 1.6 1 0 0 1 1 1 1 MYND finger V-set PF07686.12 EAU91723.1 - 0.17 11.8 1.4 2.1 8.2 0.1 2.6 2 1 1 3 3 3 0 Immunoglobulin V-set domain SWIM PF04434.12 EAU91724.1 - 1e-06 28.0 0.8 1.7e-06 27.3 0.6 1.5 1 0 0 1 1 1 1 SWIM zinc finger MFS_1 PF07690.11 EAU91725.1 - 7.3e-18 64.4 33.9 1.1e-17 63.7 23.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-U1 PF06220.7 EAU91726.1 - 1.8e-10 40.1 3.2 2.7e-10 39.6 2.2 1.3 1 0 0 1 1 1 1 U1 zinc finger Herpes_capsid PF06112.6 EAU91726.1 - 2.4 8.2 7.9 3.7 7.5 0.2 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein zf-TRM13_CCCH PF11722.3 EAU91726.1 - 2.6 7.5 5.6 6.5 6.2 3.9 1.7 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein SURF2 PF05477.6 EAU91726.1 - 3.4 6.7 6.2 0.34 10.0 0.1 2.3 3 0 0 3 3 3 0 Surfeit locus protein 2 (SURF2) Chitin_synth_1 PF01644.12 EAU91728.1 - 6.8e-79 263.3 0.1 1.1e-78 262.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EAU91728.1 - 1.4e-25 88.7 0.2 3.4e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EAU91728.1 - 1.6e-24 86.1 1.5 1.7e-16 59.7 0.0 2.2 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EAU91728.1 - 9.1e-08 32.1 0.0 3.8e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EAU91728.1 - 1.1e-07 31.7 6.5 5.2e-07 29.5 4.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 R3H PF01424.17 EAU91729.2 - 0.024 14.3 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 R3H domain MDM31_MDM32 PF08118.6 EAU91730.2 - 8e-151 502.9 6.7 4.4e-150 500.4 4.6 1.8 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins UCR_Fe-S_N PF10399.4 EAU91730.2 - 0.13 11.4 3.2 3 7.1 0.0 2.9 3 0 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LIM PF00412.17 EAU91731.1 - 0.0039 17.2 0.8 0.0055 16.7 0.5 1.3 1 0 0 1 1 1 1 LIM domain Glyco_hydro_9 PF00759.14 EAU91732.2 - 0.12 11.2 0.8 0.24 10.2 0.6 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 BAR PF03114.13 EAU91733.2 - 4.1e-50 170.4 0.3 4.7e-50 170.2 0.2 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EAU91733.2 - 0.00044 19.6 1.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 Arfaptin-like domain Toxin_52 PF15605.1 EAU91733.2 - 0.011 15.6 1.1 0.062 13.1 0.0 2.2 2 0 0 2 2 2 0 Putative toxin 52 HD_3 PF13023.1 EAU91733.2 - 0.21 11.2 1.3 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 HD domain SYF2 PF08231.7 EAU91733.2 - 0.39 10.8 3.5 1.8 8.6 2.4 2.1 1 1 0 1 1 1 0 SYF2 splicing factor AAA PF00004.24 EAU91735.2 - 2.2e-13 50.5 0.0 5.2e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 EAU91735.2 - 2.4e-11 43.4 0.0 1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 BAH domain AAA_16 PF13191.1 EAU91735.2 - 6.9e-09 35.9 0.2 1.1e-07 32.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU91735.2 - 4.8e-08 33.2 0.0 9.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU91735.2 - 0.0017 18.0 0.1 0.0059 16.3 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Nop14 PF04147.7 EAU91735.2 - 0.0022 16.0 16.8 0.0022 16.0 11.6 1.6 2 0 0 2 2 2 1 Nop14-like family NACHT PF05729.7 EAU91735.2 - 0.0072 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EAU91735.2 - 0.008 15.1 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) YL1 PF05764.8 EAU91735.2 - 0.049 13.2 23.4 0.094 12.3 13.1 2.3 2 0 0 2 2 2 0 YL1 nuclear protein AAA_11 PF13086.1 EAU91735.2 - 0.061 12.8 1.4 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EAU91735.2 - 0.065 12.9 0.1 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 NTPase TIP49 PF06068.8 EAU91735.2 - 0.069 11.8 0.1 0.93 8.1 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus DUF605 PF04652.11 EAU91735.2 - 0.07 12.5 13.8 0.11 11.8 9.5 1.2 1 0 0 1 1 1 0 Vta1 like GTPase_Cys_C PF12631.2 EAU91735.2 - 0.12 12.7 0.2 0.34 11.3 0.1 1.7 1 0 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Acyl-CoA_dh_2 PF08028.6 EAU91735.2 - 0.23 11.7 2.1 0.35 11.1 0.3 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF2890 PF11081.3 EAU91735.2 - 4.5 7.2 18.7 5.1 7.1 10.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) Mlp PF03304.8 EAU91738.2 - 0.0094 15.9 7.7 0.017 15.0 5.4 1.4 1 0 0 1 1 1 1 Mlp lipoprotein family AAA_23 PF13476.1 EAU91738.2 - 1.8 8.8 11.2 3.6 7.8 7.7 1.4 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 EAU91738.2 - 9 4.4 16.0 14 3.7 11.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein BTB PF00651.26 EAU91739.2 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 EAU91740.1 - 1.2e-06 28.1 0.1 2.9e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU91741.2 - 2.6e-05 23.8 0.1 5.8e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like Saccharop_dh PF03435.13 EAU91742.1 - 4.4e-21 75.3 0.0 6e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EAU91742.1 - 6.7e-08 32.7 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EAU91742.1 - 1.4e-07 31.2 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EAU91742.1 - 2.3e-05 24.3 1.2 4.2e-05 23.5 0.1 1.9 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EAU91742.1 - 4.2e-05 23.2 0.1 4.2e-05 23.2 0.1 2.3 3 0 0 3 3 3 1 KR domain NmrA PF05368.8 EAU91742.1 - 0.00071 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EAU91742.1 - 0.00079 18.2 0.0 0.0026 16.5 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EAU91742.1 - 0.0048 17.2 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EAU91742.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus LAGLIDADG_3 PF14528.1 EAU91743.2 - 0.28 11.4 0.1 0.59 10.4 0.0 1.5 1 0 0 1 1 1 0 LAGLIDADG-like domain DUF2360 PF10152.4 EAU91744.2 - 0.15 12.3 0.1 0.15 12.3 0.1 2.6 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) BTB PF00651.26 EAU91745.2 - 8.4e-06 25.7 0.1 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EAU91746.2 - 0.0001 22.2 0.2 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain SET PF00856.23 EAU91747.1 - 7.5e-13 49.0 0.1 4e-11 43.4 0.1 2.3 1 1 0 1 1 1 1 SET domain Glyco_hydro_31 PF01055.21 EAU91748.1 - 3.3e-143 477.7 3.4 4.4e-143 477.2 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EAU91748.1 - 1.9e-15 56.4 0.0 6.2e-15 54.8 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like Gb3_synth PF04572.7 EAU91748.1 - 0.12 12.0 0.4 0.3 10.7 0.3 1.6 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region F-box-like PF12937.2 EAU91749.2 - 1.7e-07 30.8 0.7 4.4e-07 29.5 0.5 1.7 1 0 0 1 1 1 1 F-box-like GoLoco PF02188.12 EAU91749.2 - 0.49 9.8 5.8 0.36 10.2 0.2 2.8 3 0 0 3 3 3 0 GoLoco motif AMP-binding PF00501.23 EAU91754.2 - 1.2e-43 149.1 0.3 6.9e-36 123.5 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EAU91754.2 - 3e-05 24.8 0.0 6.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2957 PF11170.3 EAU91754.2 - 0.02 13.5 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) Aconitase_2_N PF06434.8 EAU91754.2 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus RHD3 PF05879.7 EAU91755.1 - 7.4e-255 847.4 7.2 2.7e-254 845.5 5.0 1.7 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EAU91755.1 - 8.2e-07 28.3 0.2 1.5e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EAU91755.1 - 1.3e-05 25.0 0.4 3.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EAU91755.1 - 2.6e-05 24.7 0.0 7.7e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EAU91755.1 - 3.8e-05 23.6 0.0 0.00012 22.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EAU91755.1 - 0.0013 18.7 0.4 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain GAPT PF11770.3 EAU91756.1 - 0.14 11.8 0.1 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) TMEM190 PF15431.1 EAU91756.1 - 0.24 11.3 0.7 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 190 Helicase_C PF00271.26 EAU91758.2 - 1.2e-09 37.8 0.1 8.4e-09 35.1 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU91758.2 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase F-box-like PF12937.2 EAU91760.2 - 0.013 15.1 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like SHS2_Rpb7-N PF03876.12 EAU91761.1 - 3e-15 56.1 0.0 4.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EAU91761.1 - 6.2e-12 45.4 1.0 1.4e-11 44.2 0.7 1.6 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EAU91761.1 - 0.0045 17.1 0.1 0.0086 16.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 EHN PF06441.7 EAU91762.2 - 3.5e-31 107.4 0.5 7.1e-31 106.4 0.3 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EAU91762.2 - 2.9e-06 27.3 0.0 7e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU91762.2 - 0.00061 19.4 0.0 0.00098 18.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EAU91762.2 - 0.16 10.3 0.0 0.99 7.8 0.0 1.9 2 0 0 2 2 2 0 Ndr family CPSF_A PF03178.10 EAU91763.2 - 7.4e-93 311.1 0.0 9e-92 307.5 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EAU91763.2 - 7.4e-66 222.3 0.0 1.7e-65 221.1 0.0 1.6 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Slu7 PF11708.3 EAU91764.1 - 9.3e-87 290.7 15.2 9.3e-87 290.7 10.6 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EAU91764.1 - 0.02 14.5 0.9 0.047 13.3 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle TRL PF13146.1 EAU91764.1 - 0.021 14.8 0.2 0.047 13.6 0.2 1.6 1 0 0 1 1 1 0 TRL-like protein family DUF3128 PF11326.3 EAU91764.1 - 4.5 7.4 7.4 0.36 10.9 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) UDPGP PF01704.13 EAU91766.1 - 8.7e-182 604.3 0.3 1e-181 604.0 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ERO1 PF04137.10 EAU91768.2 - 3.9e-116 387.9 0.0 4.8e-116 387.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ATP-sulfurylase PF01747.12 EAU91769.1 - 3.9e-87 291.0 0.2 5.8e-87 290.5 0.1 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EAU91769.1 - 5.5e-53 178.8 0.0 8.3e-53 178.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EAU91769.1 - 6.4e-53 178.4 0.0 1.1e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EAU91769.1 - 0.018 14.9 0.9 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EAU91769.1 - 0.052 12.7 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 EAU91769.1 - 0.086 12.4 0.0 0.52 9.9 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RNase_H2-Ydr279 PF09468.5 EAU91771.2 - 2.4e-45 155.0 0.0 2.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) CBM_1 PF00734.13 EAU91773.2 - 3.2e-13 49.0 13.2 3.2e-13 49.0 9.1 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU91773.2 - 0.0032 17.4 3.2 0.0032 17.4 1.4 1.6 2 0 0 2 2 2 1 Toxin 7 SKN1 PF03935.10 EAU91774.2 - 2.3e-130 435.0 3.8 4.4e-72 242.8 0.4 2.7 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Mg_trans_NIPA PF05653.9 EAU91775.2 - 1.3e-17 63.6 13.5 2.5e-09 36.5 2.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EAU91775.2 - 0.00034 20.7 4.9 0.00034 20.7 3.4 3.8 3 2 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EAU91775.2 - 0.00055 19.9 6.8 0.00055 19.9 4.7 3.3 3 1 0 3 3 3 2 EamA-like transporter family SieB PF14163.1 EAU91775.2 - 0.033 13.7 0.5 3.2 7.3 0.1 2.6 2 0 0 2 2 2 0 Superinfection exclusion protein B Ssl1 PF04056.9 EAU91776.2 - 5.7e-60 202.2 0.1 2.8e-59 199.9 0.0 2.0 2 1 0 2 2 2 1 Ssl1-like VWA_2 PF13519.1 EAU91776.2 - 1.7e-10 41.2 0.0 2.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EAU91776.2 - 1 8.5 6.7 6.3 5.9 4.3 2.2 2 0 0 2 2 2 0 Transcription factor Tfb4 Rad10 PF03834.9 EAU91778.2 - 1.3e-27 95.2 0.0 2.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EAU91778.2 - 9.6e-08 32.0 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EAU91778.2 - 0.0011 18.8 0.0 0.0062 16.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif ABC_tran PF00005.22 EAU91779.2 - 9.2e-18 64.8 0.0 5.5e-09 36.4 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAU91779.2 - 0.0027 17.7 0.0 1.1 9.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Amidohydro_4 PF13147.1 EAU91780.1 - 1.2e-18 68.1 0.3 6.7e-17 62.4 0.2 3.0 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EAU91780.1 - 1.5e-10 40.7 0.0 9.2e-10 38.2 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EAU91780.1 - 8.6e-08 32.2 0.6 9.2e-06 25.5 0.4 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EAU91780.1 - 0.00059 19.1 0.1 0.094 11.9 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Tetraspannin PF00335.15 EAU91782.1 - 5e-05 22.6 18.2 0.0012 18.1 12.9 2.1 1 1 0 1 1 1 1 Tetraspanin family STE2 PF02116.10 EAU91782.1 - 0.35 9.8 7.6 0.66 8.9 5.3 1.3 1 1 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DUF3487 PF11990.3 EAU91782.1 - 3.6 7.0 7.9 5.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) PAM2 PF07145.10 EAU91783.2 - 0.016 14.6 1.1 0.016 14.6 0.8 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF1746 PF08508.5 EAU91784.2 - 1.1e-06 28.5 2.9 3e-06 27.1 2.0 1.7 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) UPF0203 PF05254.7 EAU91785.1 - 0.0022 17.8 1.5 0.019 14.8 1.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EAU91785.1 - 0.011 15.5 0.8 0.038 13.7 0.5 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Fungal_trans PF04082.13 EAU91787.2 - 3e-21 75.4 0.0 4.9e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 EAU91787.2 - 0.067 13.1 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF1674 PF07896.7 EAU91788.1 - 1.6e-11 44.2 2.4 2.6e-11 43.5 1.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) LSM PF01423.17 EAU91789.1 - 2.6e-12 46.0 0.3 3.4e-12 45.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAU91789.1 - 0.052 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain TPR_1 PF00515.23 EAU91791.2 - 1.9e-29 100.0 16.3 7.1e-05 22.2 0.0 7.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EAU91791.2 - 8.1e-26 89.4 15.5 1.3e-09 37.5 2.6 6.0 3 1 4 7 7 7 6 TPR repeat APC8 PF04049.8 EAU91791.2 - 1.1e-24 86.7 0.0 3.1e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.12 EAU91791.2 - 2e-22 77.2 21.4 0.0014 18.4 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EAU91791.2 - 4.1e-21 73.5 8.7 0.0048 17.4 0.1 7.7 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 EAU91791.2 - 1.1e-17 62.3 9.3 0.00043 19.8 0.0 7.1 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EAU91791.2 - 1.3e-16 60.2 21.8 1.3e-06 28.2 0.1 5.8 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EAU91791.2 - 3.1e-16 59.5 17.7 8.9e-05 23.0 1.6 7.0 4 1 4 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 EAU91791.2 - 1.4e-11 43.2 18.8 0.007 16.0 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAU91791.2 - 5.8e-10 38.5 5.2 0.1 12.8 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU91791.2 - 3.1e-07 30.6 6.8 0.67 10.3 0.1 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EAU91791.2 - 3.3e-06 26.8 13.8 0.0011 18.7 0.7 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EAU91791.2 - 9.4e-06 25.6 23.7 0.0023 18.0 2.0 6.3 5 1 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EAU91791.2 - 0.00019 21.6 13.2 7.1 7.3 0.0 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_5 PF12688.2 EAU91791.2 - 0.0018 18.2 0.7 0.92 9.5 0.0 3.3 3 1 0 3 3 3 1 Tetratrico peptide repeat ChAPs PF09295.5 EAU91791.2 - 0.002 16.9 0.6 0.44 9.2 0.0 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 EAU91791.2 - 0.0027 17.5 0.3 0.6 10.0 0.1 2.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain FAT PF02259.18 EAU91791.2 - 0.0056 15.6 0.7 0.17 10.8 0.1 2.5 1 1 1 2 2 2 1 FAT domain TPR_15 PF13429.1 EAU91791.2 - 0.0067 15.5 9.7 0.069 12.1 3.1 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 EAU91791.2 - 0.21 11.4 2.1 2.9 7.7 0.0 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) BTAD PF03704.12 EAU91791.2 - 0.64 10.3 12.5 2 8.6 0.3 4.1 4 1 1 5 5 4 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 EAU91791.2 - 1.6 8.7 21.1 4.2 7.4 0.3 6.7 7 1 1 8 8 7 0 Tetratricopeptide repeat Alg14 PF08660.6 EAU91792.2 - 6.7e-43 146.6 0.0 8.8e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF4131 PF13567.1 EAU91792.2 - 0.099 12.0 2.7 0.078 12.3 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) zf-CCCH PF00642.19 EAU91793.1 - 6.1e-14 51.2 15.3 3.7e-07 29.6 1.7 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EAU91793.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU91793.1 - 0.031 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 EAU91793.1 - 1.7 8.6 4.5 9.2 6.3 0.5 2.7 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) Peptidase_S8 PF00082.17 EAU91794.1 - 1.6e-43 148.9 17.3 2.2e-43 148.4 12.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EAU91794.1 - 1.4e-07 31.9 0.0 2.7e-06 27.8 0.0 2.6 2 1 0 2 2 2 1 Peptidase inhibitor I9 Mito_carr PF00153.22 EAU91795.1 - 9.5e-17 60.5 0.0 4.8e-09 35.8 0.0 3.2 2 1 0 2 2 2 2 Mitochondrial carrier protein EphA2_TM PF14575.1 EAU91795.1 - 0.086 13.2 0.3 1.8 9.0 0.0 3.0 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain SNF2_N PF00176.18 EAU91796.2 - 2.7e-44 151.1 0.0 1.4e-36 125.8 0.1 3.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU91796.2 - 3e-15 55.8 0.0 8.6e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_3 PF12836.2 EAU91796.2 - 0.063 13.2 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sybindin PF04099.7 EAU91797.2 - 5.9e-17 61.6 0.0 7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EAU91797.2 - 0.012 15.5 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Yip1 PF04893.12 EAU91799.1 - 2.4e-06 27.1 15.0 3.7e-06 26.5 10.4 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1168 PF06658.7 EAU91800.1 - 7.3e-41 139.0 16.2 9.8e-41 138.5 11.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF4629 PF15442.1 EAU91800.1 - 0.066 13.3 10.5 0.095 12.8 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DUF1510 PF07423.6 EAU91800.1 - 1.1 8.5 10.1 1.6 8.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_H2-Ydr279 PF09468.5 EAU91800.1 - 1.4 8.0 7.3 1.6 7.8 5.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Vfa1 PF08432.5 EAU91800.1 - 4 7.4 13.6 6.2 6.8 9.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3987 PF13148.1 EAU91800.1 - 9.5 4.6 11.9 16 3.9 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PseudoU_synth_2 PF00849.17 EAU91801.1 - 5.1e-26 91.4 0.0 1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase ThiS PF02597.15 EAU91801.1 - 0.16 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 ThiS family Cwf_Cwc_15 PF04889.7 EAU91802.2 - 2.5e-69 233.6 25.5 3.1e-69 233.3 17.7 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.6 EAU91802.2 - 0.0053 15.2 19.2 0.0066 14.8 13.3 1.1 1 0 0 1 1 1 1 SGT1 protein Nop14 PF04147.7 EAU91802.2 - 0.017 13.1 27.2 0.019 12.8 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ufd2P_core PF10408.4 EAU91802.2 - 0.091 10.9 0.6 0.12 10.5 0.4 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core Glyco_tranf_2_4 PF13704.1 EAU91802.2 - 0.11 12.8 1.5 0.19 12.0 0.4 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 Daxx PF03344.10 EAU91802.2 - 0.76 8.1 26.5 0.92 7.9 18.4 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 EAU91802.2 - 1 7.8 9.7 1.2 7.7 6.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EAU91802.2 - 3 5.7 27.3 4.3 5.2 19.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF506 PF04720.7 EAU91802.2 - 5 6.7 9.8 9.1 5.8 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Sin_N PF04801.8 EAU91802.2 - 5.9 5.6 14.0 11 4.7 9.7 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region Sporozoite_P67 PF05642.6 EAU91802.2 - 7.3 4.3 11.1 10 3.8 7.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.2 EAU91802.2 - 7.5 4.1 9.8 8.3 3.9 6.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ebola_NP PF05505.7 EAU91802.2 - 7.7 4.4 14.4 9.4 4.1 10.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein FCH PF00611.18 EAU91803.1 - 6.6e-18 64.6 0.0 1.5e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EAU91803.1 - 2.5e-11 42.7 0.3 4.7e-11 41.8 0.2 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU91803.1 - 3.2e-09 36.2 0.1 6.8e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU91803.1 - 9.5e-06 25.0 0.0 1.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain VGCC_beta4Aa_N PF12052.3 EAU91803.1 - 0.16 11.8 0.7 0.53 10.1 0.5 1.9 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal IKI3 PF04762.7 EAU91804.2 - 5.3e-249 828.7 0.0 1.5e-246 820.6 0.0 2.1 1 1 0 1 1 1 1 IKI3 family RBD-FIP PF09457.5 EAU91804.2 - 0.04 13.7 0.7 17 5.2 0.7 2.7 2 0 0 2 2 2 0 FIP domain DUF2361 PF10153.4 EAU91805.1 - 1.1e-30 106.1 13.9 1.1e-30 106.1 9.6 2.1 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) TetR_C_2 PF08361.6 EAU91805.1 - 0.15 11.9 2.9 3.6 7.5 0.5 2.3 1 1 1 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region Nucleoplasmin PF03066.10 EAU91805.1 - 0.39 10.2 6.9 1.2 8.6 4.8 1.9 1 0 0 1 1 1 0 Nucleoplasmin PIF1 PF05970.9 EAU91812.2 - 1.9e-26 92.9 0.1 1.9e-23 82.9 0.0 2.5 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAU91812.2 - 4.4e-11 42.7 0.0 3e-10 40.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU91812.2 - 0.0082 15.8 0.4 0.03 14.0 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EAU91812.2 - 0.035 14.0 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EAU91812.2 - 0.037 14.1 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.7 EAU91816.2 - 0.0005 19.8 9.8 0.0005 19.8 6.8 2.4 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EAU91816.2 - 0.041 13.0 0.3 0.081 12.0 0.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF342 PF03961.8 EAU91816.2 - 0.24 9.7 3.8 0.41 9.0 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EAU91816.2 - 1.3 6.7 3.6 2.2 6.0 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 EAU91816.2 - 3.1 6.7 9.7 6 5.8 5.8 2.0 1 1 1 2 2 2 0 TMPIT-like protein ADIP PF11559.3 EAU91816.2 - 9.4 6.1 25.1 0.029 14.2 8.8 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3318 PF11780.3 EAU91817.2 - 0.0037 16.8 0.4 0.065 12.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3318) Phlebovirus_NSM PF07246.6 EAU91817.2 - 1.5 7.9 5.1 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Peptidase_M22 PF00814.20 EAU91818.1 - 0.027 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family HSP70 PF00012.15 EAU91819.2 - 0.0095 13.8 0.1 0.025 12.4 0.1 1.6 1 1 0 1 1 1 1 Hsp70 protein StbA PF06406.6 EAU91819.2 - 0.022 13.7 0.1 0.4 9.5 0.1 2.2 1 1 0 1 1 1 0 StbA protein Peptidase_M22 PF00814.20 EAU91819.2 - 0.031 13.7 0.0 0.071 12.5 0.0 1.7 1 1 0 1 1 1 0 Glycoprotease family DDR PF08841.5 EAU91819.2 - 0.033 13.0 0.1 0.88 8.3 0.0 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EAU91819.2 - 0.057 13.0 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Abhydrolase_5 PF12695.2 EAU91819.2 - 0.11 12.2 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydantoinase_A PF01968.13 EAU91819.2 - 0.14 11.2 0.2 0.63 9.0 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase HSP70 PF00012.15 EAU91820.1 - 3.3e-05 22.0 0.0 4.8e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.6 EAU91820.1 - 0.0051 15.7 0.0 0.03 13.2 0.0 1.9 1 1 0 2 2 2 1 StbA protein FGGY_C PF02782.11 EAU91820.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RNA_pol_A_bac PF01000.21 EAU91821.2 - 3.2e-23 82.0 0.0 5e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EAU91821.2 - 2.9e-09 35.8 0.0 3.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M28 PF04389.12 EAU91824.2 - 2.6e-23 82.7 0.1 4.2e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SR-25 PF10500.4 EAU91824.2 - 0.025 14.0 15.3 0.04 13.3 10.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M42 PF05343.9 EAU91824.2 - 0.059 12.1 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DUF4131 PF13567.1 EAU91824.2 - 4.1 6.7 13.9 4 6.8 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) AF-4 PF05110.8 EAU91824.2 - 4.6 4.9 16.1 6.6 4.4 11.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NPV_P10 PF05531.7 EAU91826.2 - 0.0085 16.3 0.7 0.017 15.3 0.5 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.1 EAU91826.2 - 0.13 12.6 0.9 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF2944 PF11161.3 EAU91827.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Sugar_tr PF00083.19 EAU91829.2 - 2.8e-72 243.7 23.6 4.2e-69 233.2 6.4 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EAU91829.2 - 2.7e-25 88.8 29.1 3.2e-24 85.3 15.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EAU91829.2 - 0.0025 16.5 0.2 0.0046 15.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) WD40 PF00400.27 EAU91830.2 - 9.6e-30 101.3 12.6 7.2e-07 28.8 0.0 6.5 5 1 1 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EAU91830.2 - 9e-07 28.7 0.6 0.003 17.3 0.2 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EAU91830.2 - 0.1 10.3 0.1 0.19 9.4 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Pinin_SDK_memA PF04696.8 EAU91835.1 - 5.7e-07 29.1 9.2 5.7e-07 29.1 6.3 3.2 2 1 1 3 3 3 2 pinin/SDK/memA/ protein conserved region Herpes_UL95 PF03038.9 EAU91835.1 - 0.0083 15.0 1.3 0.073 11.9 0.0 2.0 2 0 0 2 2 2 2 UL95 family MFS_1 PF07690.11 EAU91836.2 - 1.4e-11 43.6 40.9 3e-11 42.6 28.3 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Cellulase PF00150.13 EAU91838.2 - 1.4e-06 27.7 0.0 2.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 EAU91838.2 - 0.0022 17.8 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF1183 PF06682.7 EAU91838.2 - 0.0033 17.1 0.8 0.0044 16.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) DUF4366 PF14283.1 EAU91838.2 - 0.021 14.2 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF912 PF06024.7 EAU91838.2 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TEA PF01285.13 EAU91839.1 - 2.3e-12 46.8 0.2 3.8e-12 46.0 0.1 1.4 1 1 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EAU91839.1 - 0.075 13.1 0.4 0.72 9.9 0.2 2.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain Dynamin_M PF01031.15 EAU91841.2 - 1.5e-23 83.0 0.0 1.5e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EAU91841.2 - 7e-23 81.2 0.0 1.6e-22 80.1 0.0 1.6 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 EAU91841.2 - 3.5e-13 49.2 0.1 6.9e-12 45.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EAU91841.2 - 5.8e-05 23.0 0.0 0.00026 20.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hemerythrin PF01814.18 EAU91841.2 - 0.00097 19.3 0.8 0.078 13.1 0.0 3.0 3 0 0 3 3 3 1 Hemerythrin HHE cation binding domain Miro PF08477.8 EAU91841.2 - 0.0066 16.9 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EAU91841.2 - 0.019 15.2 0.0 0.1 12.8 0.0 2.2 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 EAU91841.2 - 0.03 13.8 0.2 0.067 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 EAU91841.2 - 0.032 14.2 0.0 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EAU91841.2 - 0.12 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EAU91841.2 - 0.18 11.0 0.0 0.86 8.8 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 EAU91841.2 - 0.24 11.7 0.6 2.3 8.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain polyprenyl_synt PF00348.12 EAU91842.1 - 7.3e-51 172.5 0.0 9e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase PHD PF00628.24 EAU91845.2 - 0.071 12.8 1.2 6.7 6.4 0.1 3.1 3 0 0 3 3 3 0 PHD-finger zf-Sec23_Sec24 PF04810.10 EAU91845.2 - 0.49 9.9 4.4 4.7 6.8 0.0 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger F-box-like PF12937.2 EAU91846.2 - 0.0017 18.0 0.2 0.0052 16.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like APH PF01636.18 EAU91847.2 - 0.00012 21.9 0.0 0.00045 20.0 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family zf-MYND PF01753.13 EAU91848.1 - 4.9e-07 29.5 15.9 8.8e-07 28.6 11.0 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EAU91849.1 - 7e-08 32.2 8.0 1.1e-07 31.5 5.6 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EAU91849.1 - 3.6 7.3 8.8 12 5.6 6.2 1.8 1 1 1 2 2 2 0 HIT zinc finger zf-MYND PF01753.13 EAU91850.1 - 1.9e-07 30.8 12.7 3.2e-07 30.1 8.8 1.4 1 0 0 1 1 1 1 MYND finger DRIM PF07539.7 EAU91851.2 - 4.8e-34 116.7 0.1 2.6e-33 114.3 0.0 2.4 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EAU91851.2 - 0.0034 17.3 2.4 27 5.1 0.0 5.4 4 0 0 4 4 4 2 HEAT repeat CoA_transf_3 PF02515.12 EAU91857.2 - 5.8e-44 149.6 0.0 7.6e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Lactonase PF10282.4 EAU91858.1 - 5.8e-52 176.8 0.0 7e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.6 EAU91858.1 - 0.15 10.9 0.0 0.79 8.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DUF3357 PF11837.3 EAU91859.2 - 0.0028 17.4 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) TMEM51 PF15345.1 EAU91859.2 - 0.0046 16.6 0.6 1.4 8.5 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein 51 Herpes_gE PF02480.11 EAU91859.2 - 0.031 12.5 0.0 0.055 11.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E P12 PF12669.2 EAU91859.2 - 0.042 14.0 0.3 0.071 13.3 0.2 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF1191 PF06697.7 EAU91859.2 - 0.1 11.4 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PrpF PF04303.8 EAU91860.1 - 5.2e-65 219.5 1.4 1.7e-62 211.3 1.0 3.4 1 1 0 1 1 1 1 PrpF protein DUF3554 PF12074.3 EAU91861.2 - 2.2e-37 129.2 0.1 3.5e-35 122.0 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EAU91861.2 - 1.4e-36 124.6 37.5 7.4e-08 32.5 0.0 14.8 10 3 8 19 19 19 12 HEAT repeats HEAT_EZ PF13513.1 EAU91861.2 - 3.4e-36 122.8 29.3 4.4e-05 23.8 0.1 19.5 18 3 5 23 23 21 11 HEAT-like repeat HEAT PF02985.17 EAU91861.2 - 1.1e-34 115.3 16.7 0.024 14.6 0.0 17.3 18 0 0 18 18 17 8 HEAT repeat CLASP_N PF12348.3 EAU91861.2 - 1.9e-11 43.7 0.0 4.9e-05 22.7 0.0 5.5 3 1 3 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EAU91861.2 - 2.7e-07 30.8 0.0 4.5 7.7 0.0 7.3 7 1 2 9 9 9 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EAU91861.2 - 1.9e-06 26.5 0.0 0.39 8.9 0.0 6.1 5 3 0 6 6 6 2 Adaptin N terminal region ParcG PF10274.4 EAU91861.2 - 0.00014 21.7 1.0 17 5.2 0.0 5.8 5 2 2 7 7 7 0 Parkin co-regulated protein Cnd1 PF12717.2 EAU91861.2 - 0.0053 16.6 0.0 78 3.0 0.0 5.9 6 2 2 8 8 8 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EAU91861.2 - 0.0074 16.2 5.9 1.9 8.5 0.3 4.9 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion UME PF08064.8 EAU91861.2 - 0.13 12.2 0.8 40 4.2 0.0 4.4 4 0 0 4 4 4 0 UME (NUC010) domain CTK3 PF12243.3 EAU91862.2 - 5.9e-43 145.8 0.1 1.6e-29 102.3 0.0 2.2 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EAU91862.2 - 6.3e-17 61.3 11.4 2.4e-14 53.1 0.9 2.4 1 1 1 2 2 2 2 CTD kinase subunit gamma CTK3 C-terminus zf-MYND PF01753.13 EAU91866.1 - 4.6e-07 29.5 15.0 7.9e-07 28.8 10.4 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 EAU91867.1 - 0.029 14.0 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like Phage_holin_3 PF05106.7 EAU91867.1 - 0.074 13.0 0.2 0.2 11.6 0.1 1.7 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) tRNA-synt_2 PF00152.15 EAU91868.1 - 5.9e-75 252.1 0.0 9.4e-75 251.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAU91868.1 - 9.6e-10 38.1 0.0 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_fac-A_3 PF08661.6 EAU91868.1 - 0.019 14.8 0.0 0.054 13.3 0.0 1.7 2 0 0 2 2 2 0 Replication factor A protein 3 Med19 PF10278.4 EAU91868.1 - 0.021 14.5 6.1 0.038 13.6 4.2 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Slu7 PF11708.3 EAU91868.1 - 0.022 14.5 7.4 0.034 13.9 5.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor PASTA PF03793.14 EAU91868.1 - 0.047 13.3 0.0 0.47 10.1 0.0 2.5 2 0 0 2 2 2 0 PASTA domain Sec62 PF03839.11 EAU91868.1 - 0.92 8.8 7.0 1.6 8.1 4.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Lge1 PF11488.3 EAU91871.1 - 0.049 13.8 1.2 0.082 13.1 0.1 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 GvpL_GvpF PF06386.6 EAU91871.1 - 0.11 12.0 1.9 0.11 12.0 0.8 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Borrelia_lipo_1 PF05714.6 EAU91871.1 - 0.32 10.0 2.7 3.2 6.8 0.4 2.0 2 0 0 2 2 2 0 Borrelia burgdorferi virulent strain associated lipoprotein TP_methylase PF00590.15 EAU91872.1 - 7.5e-21 74.8 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases F-box-like PF12937.2 EAU91873.2 - 6.5e-07 28.9 1.4 4.7e-06 26.2 0.2 2.4 2 0 0 2 2 2 1 F-box-like DUF1478 PF07349.6 EAU91873.2 - 0.0077 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1478) F-box-like PF12937.2 EAU91874.1 - 6.7e-05 22.5 1.5 0.00014 21.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EAU91875.2 - 7.4e-50 167.2 3.3 1.4e-48 163.1 2.3 2.4 1 1 0 1 1 1 1 F-box-like domain F-box PF00646.28 EAU91875.2 - 0.00028 20.4 3.0 0.00039 20.0 0.7 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAU91875.2 - 0.017 14.8 0.7 0.017 14.8 0.5 2.9 4 0 0 4 4 4 0 F-box-like DFF-C PF09033.5 EAU91876.1 - 0.041 13.7 0.1 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Phage_holin_3 PF05106.7 EAU91876.1 - 0.21 11.5 0.3 0.57 10.2 0.1 1.7 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) Glyco_hydro_10 PF00331.15 EAU91879.1 - 3.4e-109 364.7 0.0 3.9e-109 364.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 EAU91879.1 - 0.019 15.3 0.0 0.048 14.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 EAU91880.2 - 3.4e-102 341.7 0.0 4.1e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Cellulase-like PF12876.2 EAU91880.2 - 0.014 15.8 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF4339 PF14237.1 EAU91880.2 - 0.067 12.7 0.3 0.25 10.9 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) LSM PF01423.17 EAU91881.2 - 1.8e-15 56.2 0.0 3.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 LSM domain Evr1_Alr PF04777.8 EAU91882.2 - 5e-29 100.0 0.9 7.5e-29 99.4 0.2 1.5 2 0 0 2 2 2 1 Erv1 / Alr family Kri1_C PF12936.2 EAU91884.1 - 5.2e-28 96.8 0.7 5.2e-28 96.8 0.5 6.1 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 EAU91884.1 - 2.5e-21 75.8 11.9 2.5e-21 75.8 8.3 8.0 8 2 0 8 8 8 2 KRI1-like family SnoaL_2 PF12680.2 EAU91886.1 - 0.087 13.2 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain DUF4098 PF13345.1 EAU91888.1 - 0.00035 20.4 5.7 0.00073 19.4 0.1 3.6 3 1 1 4 4 4 2 Domain of unknown function (DUF4098) Glyco_hydro_71 PF03659.9 EAU91889.2 - 2.1e-91 306.2 2.7 2.7e-91 305.9 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Abhydrolase_1 PF00561.15 EAU91890.2 - 2.9e-09 36.8 0.0 4.5e-09 36.2 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU91890.2 - 2.6e-08 34.0 0.0 6e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU91890.2 - 1.1e-07 31.6 0.0 6.7e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAU91890.2 - 0.00051 19.8 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EAU91890.2 - 0.046 13.1 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase F-box-like_2 PF13013.1 EAU91891.1 - 2.7e-13 49.5 3.0 2.8e-13 49.5 0.6 2.2 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 EAU91891.1 - 1.9e-07 30.5 0.1 1.2e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAU91891.1 - 0.00089 18.9 0.0 0.0031 17.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EAU91891.1 - 2.9 8.2 12.7 0.21 11.7 0.2 4.9 6 0 0 6 6 6 0 Leucine Rich repeat BTB PF00651.26 EAU91892.2 - 9e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BRF1 PF07741.8 EAU91892.2 - 0.17 12.1 10.4 1.9 8.7 5.7 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF1515 PF07439.6 EAU91892.2 - 0.4 10.5 1.7 0.81 9.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) BTB PF00651.26 EAU91893.1 - 0.0008 19.3 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain DUF2335 PF10097.4 EAU91895.1 - 0.019 14.5 0.4 0.035 13.7 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) zf-MYND PF01753.13 EAU91896.1 - 1.2e-08 34.6 9.2 2.1e-08 33.8 6.4 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EAU91896.1 - 0.77 9.6 3.7 1.4 8.8 2.6 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 BTB PF00651.26 EAU91897.1 - 1.1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EAU91898.2 - 7.1e-12 45.3 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain HSP20 PF00011.16 EAU91899.1 - 9e-22 76.8 0.0 2.6e-21 75.3 0.0 1.6 1 1 1 2 2 2 1 Hsp20/alpha crystallin family BON PF04972.12 EAU91899.1 - 0.047 13.4 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 BON domain CS PF04969.11 EAU91899.1 - 0.12 12.9 0.0 2.3 8.8 0.0 2.1 2 0 0 2 2 2 0 CS domain HSP20 PF00011.16 EAU91901.1 - 1.1e-21 76.5 0.0 1.3e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EAU91901.1 - 0.075 13.5 0.0 0.89 10.1 0.0 2.0 2 0 0 2 2 2 0 CS domain BON PF04972.12 EAU91901.1 - 0.082 12.6 0.0 2.9 7.7 0.0 2.1 2 0 0 2 2 2 0 BON domain DUF4097 PF13349.1 EAU91901.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Citrate_synt PF00285.16 EAU91902.2 - 0.00081 18.2 0.0 0.03 13.0 0.0 2.0 1 1 0 2 2 2 2 Citrate synthase F-box-like_2 PF13013.1 EAU91903.2 - 7.6e-18 64.2 2.0 1.2e-17 63.5 0.8 1.8 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 EAU91903.2 - 0.00051 19.6 0.5 0.0015 18.1 0.3 1.9 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.1 EAU91903.2 - 0.0031 17.4 0.0 0.016 15.2 0.0 2.3 1 0 0 1 1 1 1 Leucine Rich repeat Init_tRNA_PT PF04179.7 EAU91904.2 - 5.7e-80 269.3 0.0 4.5e-74 249.9 0.0 2.6 1 1 1 2 2 2 2 Initiator tRNA phosphoribosyl transferase BTB PF00651.26 EAU91905.2 - 3.9e-15 55.7 0.0 5.5e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain HSP20 PF00011.16 EAU91906.1 - 9.5e-22 76.7 0.1 3e-21 75.1 0.0 1.7 1 1 1 2 2 2 1 Hsp20/alpha crystallin family DUF4097 PF13349.1 EAU91906.1 - 0.03 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) BON PF04972.12 EAU91906.1 - 0.038 13.7 0.1 6.9 6.5 0.0 2.2 2 0 0 2 2 2 0 BON domain Calpain_III PF01067.17 EAU91907.2 - 2.4e-25 88.8 0.0 1.5e-09 37.6 0.0 3.6 2 1 1 3 3 3 3 Calpain large subunit, domain III Peptidase_C2 PF00648.16 EAU91907.2 - 9e-15 54.4 0.0 3.8e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 EAU91907.2 - 1.4e-05 24.8 0.6 2.9e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 EAU91907.2 - 0.0074 15.8 1.0 0.021 14.4 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EAU91907.2 - 0.0091 15.6 0.2 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 TPR repeat BTB PF00651.26 EAU91908.2 - 2.1e-07 30.8 0.0 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EAU91909.2 - 0.00099 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 EAU91911.2 - 1.9e-08 33.8 0.6 4.5e-08 32.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like OPT PF03169.10 EAU91912.1 - 1.9e-192 641.0 40.3 2.2e-192 640.8 27.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BTB PF00651.26 EAU91913.2 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Cep57_MT_bd PF06657.8 EAU91913.2 - 0.43 10.5 12.2 0.21 11.5 4.6 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SpoIIIAH PF12685.2 EAU91913.2 - 4.1 6.8 13.9 6.5 6.2 9.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Macoilin PF09726.4 EAU91913.2 - 6.2 4.9 19.6 8.1 4.5 13.6 1.1 1 0 0 1 1 1 0 Transmembrane protein SlyX PF04102.7 EAU91913.2 - 10 6.6 7.9 57 4.1 0.1 3.4 1 1 2 3 3 3 0 SlyX F-box-like PF12937.2 EAU91914.1 - 4.1e-07 29.6 1.8 1.3e-06 28.0 1.3 1.9 1 0 0 1 1 1 1 F-box-like FBA_2 PF07735.12 EAU91914.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 F-box associated DED PF01335.16 EAU91914.1 - 0.1 12.7 0.1 0.29 11.2 0.1 1.8 2 0 0 2 2 2 0 Death effector domain DnaJ PF00226.26 EAU91917.1 - 7.6e-12 44.7 0.0 1.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain UPF0113 PF03657.8 EAU91917.1 - 0.026 14.1 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0113) Macoilin PF09726.4 EAU91921.2 - 3 6.0 4.9 4 5.6 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein ER_lumen_recept PF00810.13 EAU91922.2 - 1.2e-58 197.7 9.7 1.6e-58 197.4 6.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EAU91922.2 - 0.06 12.9 5.1 0.076 12.5 0.1 3.1 3 0 0 3 3 3 0 PQ loop repeat Arch_ATPase PF01637.13 EAU91924.2 - 0.00074 19.2 0.0 0.0024 17.6 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase ORC3_N PF07034.6 EAU91924.2 - 0.00084 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus AAA_16 PF13191.1 EAU91924.2 - 0.002 18.1 0.0 0.014 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EAU91924.2 - 0.0022 18.2 0.5 0.026 14.7 0.3 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EAU91924.2 - 0.003 16.6 0.0 0.0058 15.6 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 EAU91924.2 - 0.0033 17.1 0.8 0.096 12.3 0.5 2.6 1 1 0 1 1 1 1 NACHT domain DUF2057 PF09829.4 EAU91924.2 - 0.014 15.0 0.4 0.033 13.8 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) C2 PF00168.25 EAU91924.2 - 0.046 13.5 0.1 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 C2 domain RNA_helicase PF00910.17 EAU91924.2 - 0.092 12.9 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Lectin_leg-like PF03388.8 EAU91925.1 - 1.9e-61 207.1 0.4 2.6e-61 206.6 0.3 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EAU91925.1 - 0.0083 15.5 0.0 0.067 12.5 0.0 2.2 1 1 0 1 1 1 1 Legume lectin domain ATPase_gene1 PF09527.5 EAU91925.1 - 0.01 15.6 0.8 0.01 15.6 0.6 1.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF3836 PF12930.2 EAU91925.1 - 0.083 12.3 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF3836) HEAT_EZ PF13513.1 EAU91926.2 - 1.3e-24 85.9 23.7 1e-09 38.5 0.0 11.4 8 5 5 13 13 13 4 HEAT-like repeat HEAT PF02985.17 EAU91926.2 - 7.1e-23 78.5 15.7 2e-05 24.2 0.0 10.4 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.1 EAU91926.2 - 2.4e-22 79.0 0.1 2.9e-05 24.2 0.0 7.3 5 3 3 8 8 8 4 HEAT repeats Arm PF00514.18 EAU91926.2 - 1.8e-07 30.6 5.2 0.4 10.5 0.0 6.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EAU91926.2 - 4.9e-07 29.5 0.1 3.4e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EAU91926.2 - 7.1e-07 29.5 0.1 0.11 12.8 0.1 4.7 4 1 2 6 6 5 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EAU91926.2 - 1.2e-06 28.5 1.7 1.6 8.5 0.1 6.3 5 2 2 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 EAU91926.2 - 3.1e-06 27.0 0.1 0.031 14.2 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EAU91926.2 - 0.00066 18.1 0.6 1.9 6.6 0.2 3.6 2 1 1 3 3 3 1 Adaptin N terminal region DUF2454 PF10521.4 EAU91926.2 - 0.091 11.7 0.1 8.9 5.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) RIX1 PF08167.7 EAU91926.2 - 0.092 12.4 0.4 27 4.3 0.0 3.9 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis RasGEF_N_2 PF14663.1 EAU91926.2 - 0.12 12.3 0.4 4.7 7.1 0.0 3.4 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain FSH1 PF03959.8 EAU91927.2 - 2.4e-52 177.4 0.0 3.1e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EAU91927.2 - 4.5e-05 23.4 0.1 0.0001 22.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU91927.2 - 0.011 15.5 0.0 0.028 14.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mito_carr PF00153.22 EAU91928.2 - 8.1e-70 230.6 3.9 1.1e-22 79.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Homeobox PF00046.24 EAU91930.2 - 0.00011 21.7 0.1 0.0014 18.2 0.0 2.2 2 0 0 2 2 2 1 Homeobox domain Fic PF02661.13 EAU91937.1 - 2.6e-09 37.6 0.0 5.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Fic/DOC family Mod_r PF07200.8 EAU91940.1 - 0.00051 19.9 0.8 0.0012 18.7 0.6 1.6 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF2335 PF10097.4 EAU91940.1 - 0.0016 18.0 0.7 0.0032 17.0 0.5 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2335) HIGH_NTase1 PF05636.6 EAU91940.1 - 0.0093 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 HIGH Nucleotidyl Transferase zf-C4H2 PF10146.4 EAU91940.1 - 0.18 11.7 1.5 0.26 11.2 1.0 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Ank PF00023.25 EAU91941.2 - 2.6e-38 127.9 4.4 1.3e-05 24.7 0.0 9.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_2 PF12796.2 EAU91941.2 - 2.2e-35 120.8 1.3 2.5e-10 40.5 0.1 5.2 2 1 4 6 6 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU91941.2 - 1.5e-31 108.2 2.7 6.5e-09 36.0 0.0 6.9 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU91941.2 - 8.6e-24 81.2 0.1 0.0065 16.6 0.0 8.6 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 EAU91941.2 - 3.7e-23 81.0 11.0 6.7e-07 29.3 0.4 7.6 3 1 5 8 8 8 6 Ankyrin repeats (many copies) AAA_22 PF13401.1 EAU91941.2 - 3.8e-05 23.8 0.0 0.00015 21.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAU91941.2 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 EAU91941.2 - 0.013 15.7 0.0 0.053 13.8 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 EAU91941.2 - 0.023 14.7 0.1 0.12 12.3 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EAU91941.2 - 0.028 14.0 0.0 0.072 12.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 EAU91941.2 - 0.046 14.5 0.0 0.14 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EAU91941.2 - 0.12 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Waikav_capsid_1 PF12264.3 EAU91941.2 - 0.14 11.3 0.2 7.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Waikavirus capsid protein 1 Reo_sigmaC PF04582.7 EAU91942.2 - 0.0069 15.6 2.7 0.73 8.9 0.1 2.2 2 0 0 2 2 2 2 Reovirus sigma C capsid protein Laminin_II PF06009.7 EAU91942.2 - 0.0082 15.9 0.2 0.0082 15.9 0.1 3.5 3 1 0 3 3 3 1 Laminin Domain II DUF3584 PF12128.3 EAU91942.2 - 0.043 11.1 7.3 0.071 10.4 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 EAU91942.2 - 0.047 13.2 12.2 0.56 9.7 1.1 3.7 1 1 2 4 4 4 0 IncA protein DivIC PF04977.10 EAU91942.2 - 0.063 12.7 8.6 2.2 7.8 0.3 3.5 3 0 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.3 EAU91942.2 - 0.2 11.4 9.9 2.6 7.9 1.2 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.1 EAU91942.2 - 0.89 9.2 4.8 13 5.4 0.0 3.7 3 1 1 4 4 4 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.7 EAU91942.2 - 1.2 8.9 4.5 1.4 8.7 0.1 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EAU91942.2 - 1.3 8.8 6.4 1.3 8.8 0.0 3.3 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 EAU91942.2 - 6 6.9 10.2 2.1 8.4 0.5 3.3 4 0 0 4 4 4 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 EAU91942.2 - 6.6 7.0 9.5 0.35 11.1 0.4 3.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF3656 PF12392.3 EAU91943.1 - 0.035 14.1 0.5 0.073 13.1 0.4 1.5 1 0 0 1 1 1 0 Collagenase DUF4168 PF13767.1 EAU91943.1 - 0.089 13.4 0.1 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) TEX12 PF15219.1 EAU91943.1 - 0.09 12.7 0.4 0.29 11.1 0.1 2.0 2 1 0 2 2 2 0 Testis-expressed 12 Synaptobrevin PF00957.16 EAU91943.1 - 5.7 6.6 6.9 1.1 8.9 0.1 2.8 3 0 0 3 3 3 0 Synaptobrevin ARD PF03079.9 EAU91946.1 - 3.3e-46 157.1 0.0 3.9e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EAU91946.1 - 7.5e-10 38.1 0.0 1.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EAU91946.1 - 3.1e-06 26.9 0.0 4.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EAU91946.1 - 6.7e-05 22.3 0.0 9.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 EAU91946.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.7 EAU91946.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ARD PF03079.9 EAU91947.1 - 9e-38 129.6 0.4 1.1e-37 129.4 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EAU91947.1 - 6.9e-08 31.8 0.1 1.3e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EAU91947.1 - 6.1e-07 29.1 0.1 9.6e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Ribosomal_L33 PF00471.15 EAU91948.1 - 5.2e-09 36.1 0.0 6.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.3 EAU91948.1 - 0.034 13.6 0.1 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal PMT_C PF11647.3 EAU91954.1 - 0.075 12.6 0.1 0.21 11.2 0.1 1.8 1 1 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 DUF4404 PF14357.1 EAU91954.1 - 0.1 13.0 2.6 0.61 10.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HALZ PF02183.13 EAU91954.1 - 0.26 11.0 4.6 0.69 9.6 3.2 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pentapeptide PF00805.17 EAU91955.2 - 0.15 11.3 0.1 0.73 9.1 0.0 1.9 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Mito_carr PF00153.22 EAU91957.2 - 1e-46 156.5 1.5 4.3e-19 68.0 0.0 3.8 3 1 1 4 4 4 3 Mitochondrial carrier protein Tim17 PF02466.14 EAU91957.2 - 0.23 11.5 2.3 3 7.8 0.4 3.0 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RNase_T PF00929.19 EAU91958.1 - 5.7e-21 75.4 0.0 8.2e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EAU91958.1 - 0.0005 19.5 0.0 0.001 18.5 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease Alpha_kinase PF02816.13 EAU91960.2 - 1.2e-15 57.7 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family TMPIT PF07851.8 EAU91963.2 - 2.4 7.1 6.4 0.81 8.6 0.9 2.3 2 1 1 3 3 3 0 TMPIT-like protein IncA PF04156.9 EAU91963.2 - 3.7 7.0 11.5 9.7 5.7 8.0 1.7 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EAU91963.2 - 5.9 4.6 7.1 8.5 4.0 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APH PF01636.18 EAU91966.1 - 4.1e-14 52.8 0.8 6.4e-14 52.2 0.6 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU91966.1 - 7.1e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EAU91966.1 - 0.0023 17.3 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Cpn60_TCP1 PF00118.19 EAU91967.2 - 4.3e-124 414.8 0.0 5.2e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1996 PF09362.5 EAU91972.2 - 9.9e-45 153.0 0.0 1.3e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU91972.2 - 5e-12 45.2 14.8 1.3e-11 43.8 10.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1996 PF09362.5 EAU91973.2 - 2.7e-69 233.4 0.0 3.3e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU91973.2 - 2e-11 43.3 14.4 2e-11 43.3 10.0 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF1996 PF09362.5 EAU91974.2 - 3.8e-68 229.6 0.0 4.6e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU91974.2 - 2e-11 43.3 14.4 2e-11 43.3 10.0 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain FAD_binding_3 PF01494.14 EAU91975.1 - 1.7e-15 56.9 1.4 1.4e-07 30.9 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EAU91975.1 - 0.0061 15.4 0.0 0.014 14.2 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 EAU91975.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EAU91975.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DnaJ PF00226.26 EAU91976.2 - 4.5e-24 83.9 2.7 5.5e-24 83.6 1.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4491 PF14898.1 EAU91976.2 - 0.17 12.0 1.9 0.36 11.0 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Sigma70_ner PF04546.8 EAU91976.2 - 0.72 9.4 4.2 0.91 9.0 0.5 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Tic20 PF09685.5 EAU91977.1 - 0.00099 19.0 1.0 0.0015 18.4 0.7 1.2 1 0 0 1 1 1 1 Tic20-like protein YjgP_YjgQ PF03739.9 EAU91977.1 - 0.0092 14.7 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Ctr PF04145.10 EAU91977.1 - 0.019 15.0 1.9 0.051 13.6 0.1 2.2 2 1 0 2 2 2 0 Ctr copper transporter family FxsA PF04186.8 EAU91977.1 - 0.019 14.5 4.0 0.033 13.8 2.7 1.3 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Mem_trans PF03547.13 EAU91977.1 - 0.08 11.2 0.5 0.14 10.3 0.0 1.6 2 0 0 2 2 2 0 Membrane transport protein DUF2207 PF09972.4 EAU91977.1 - 0.19 10.2 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF912 PF06024.7 EAU91977.1 - 0.42 10.6 4.9 0.18 11.8 0.2 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_UL45 PF05473.7 EAU91977.1 - 0.55 9.6 3.2 0.22 10.8 0.1 1.9 2 0 0 2 2 2 0 UL45 protein Vma12 PF11712.3 EAU91977.1 - 2.4 7.8 5.7 0.88 9.2 1.2 2.2 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cu-oxidase PF00394.17 EAU91978.1 - 1.7e-44 151.4 0.1 6.3e-42 143.1 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU91978.1 - 2.1e-39 133.9 0.2 1.3e-38 131.3 0.1 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU91978.1 - 1e-36 125.5 1.3 4.5e-33 113.6 0.0 3.8 4 1 0 4 4 4 2 Multicopper oxidase CFEM PF05730.6 EAU91979.1 - 3.5e-11 42.7 14.2 5.4e-11 42.1 9.9 1.3 1 0 0 1 1 1 1 CFEM domain WSC PF01822.14 EAU91979.1 - 0.73 9.8 11.1 0.92 9.4 6.9 1.8 1 1 0 1 1 1 0 WSC domain CHAT PF12770.2 EAU91980.2 - 9.5e-32 110.2 0.0 2.8e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EAU91980.2 - 2.4e-08 33.7 13.7 0.12 12.3 0.8 8.3 5 2 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EAU91980.2 - 1.2e-05 25.5 8.7 0.89 10.3 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat Peptidase_S46 PF10459.4 EAU91980.2 - 0.022 13.1 0.0 0.037 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase S46 Peptidase_C25 PF01364.13 EAU91980.2 - 0.21 10.5 0.3 0.97 8.3 0.1 1.9 2 0 0 2 2 2 0 Peptidase family C25 DUF948 PF06103.6 EAU91980.2 - 0.22 11.4 0.9 0.93 9.3 0.0 2.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) TPR_10 PF13374.1 EAU91980.2 - 1.3 9.1 13.3 0.94 9.5 0.2 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat RhoGAP PF00620.22 EAU91983.1 - 3.9e-11 42.7 0.0 2e-10 40.5 0.0 2.2 1 1 0 1 1 1 1 RhoGAP domain Cwf_Cwc_15 PF04889.7 EAU91983.1 - 0.013 15.1 1.6 0.028 14.1 1.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YfhO PF09586.5 EAU91984.2 - 0.029 12.4 1.5 0.037 12.0 1.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Cu-oxidase PF00394.17 EAU91985.2 - 5.3e-44 149.9 0.0 1.1e-41 142.3 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU91985.2 - 6.3e-38 129.1 0.5 5.9e-36 122.7 0.2 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU91985.2 - 8.1e-37 125.8 2.5 5.6e-35 119.8 0.0 3.0 2 1 0 2 2 2 2 Multicopper oxidase Abhydrolase_5 PF12695.2 EAU91987.1 - 0.0011 18.7 0.0 0.0025 17.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAU91987.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_M22 PF00814.20 EAU91987.1 - 0.057 12.9 0.0 0.09 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family Abhydrolase_6 PF12697.2 EAU91987.1 - 0.081 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GMC_oxred_C PF05199.8 EAU91988.2 - 4.3e-27 95.1 1.2 1.2e-26 93.7 0.9 1.7 1 1 0 1 1 1 1 GMC oxidoreductase RNase_PH PF01138.16 EAU91989.2 - 2.9e-19 69.6 0.4 7e-19 68.4 0.2 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EAU91989.2 - 0.00086 19.1 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 F-box-like PF12937.2 EAU91990.1 - 1.4e-08 34.3 5.7 1.6e-08 34.1 1.5 2.8 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 EAU91990.1 - 0.028 14.1 2.1 0.2 11.4 1.4 2.4 1 1 0 1 1 1 0 F-box-like domain DUF4122 PF13498.1 EAU91991.2 - 0.3 10.4 1.9 0.64 9.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) zf-MYND PF01753.13 EAU91994.1 - 1.6e-11 43.8 12.5 2.3e-11 43.3 8.7 1.3 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.1 EAU91994.1 - 1.8e-05 24.2 0.1 0.16 11.6 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EAU91994.1 - 0.0013 18.6 0.2 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EAU91994.1 - 0.0031 17.2 0.4 2.8 8.0 0.5 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU91994.1 - 0.0074 16.8 0.5 5.4 7.9 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU91994.1 - 0.018 14.6 0.2 0.62 9.7 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAU91994.1 - 0.14 12.8 0.3 18 6.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat EphA2_TM PF14575.1 EAU91996.2 - 0.02 15.3 0.1 0.049 14.0 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EAU91996.2 - 0.021 13.1 0.0 0.035 12.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EAU91996.2 - 0.068 12.8 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family CcmD PF04995.9 EAU91996.2 - 0.11 12.2 1.5 0.24 11.1 1.0 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4381 PF14316.1 EAU91996.2 - 0.18 11.8 0.1 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) zf-MYND PF01753.13 EAU91997.1 - 2.8e-10 39.8 16.6 4.6e-10 39.2 11.5 1.4 1 0 0 1 1 1 1 MYND finger TPR_21 PF09976.4 EAU91997.1 - 0.036 13.9 0.1 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat PolC_DP2 PF03833.8 EAU91997.1 - 0.2 9.3 2.3 0.24 9.0 1.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-HIT PF04438.11 EAU91997.1 - 0.31 10.7 9.2 0.54 9.9 6.4 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.1 EAU91997.1 - 0.53 10.1 5.2 1.1 9.1 3.6 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 p450 PF00067.17 EAU91998.2 - 8.1e-54 182.8 0.0 1.3e-53 182.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 EAU92000.2 - 1.1e-91 307.5 0.0 6.2e-69 232.5 0.1 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family F-box PF00646.28 EAU92001.2 - 0.00012 21.6 0.2 0.00028 20.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92001.2 - 0.048 13.3 1.5 0.058 13.1 0.1 1.9 2 0 0 2 2 2 0 F-box-like EF-hand_1 PF00036.27 EAU92003.1 - 1.8e-19 67.4 1.2 1.2e-06 27.4 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EAU92003.1 - 2.9e-16 57.8 0.9 9.5e-07 28.2 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EAU92003.1 - 1.4e-15 57.1 0.1 5.9e-09 35.9 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EAU92003.1 - 1.7e-13 49.1 1.1 0.0009 18.4 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EAU92003.1 - 6.7e-12 44.8 2.1 3.3e-06 26.6 0.0 3.7 3 1 1 4 4 4 2 EF-hand domain pair F-box-like PF12937.2 EAU92004.2 - 2.1e-11 43.3 0.1 6.4e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92004.2 - 0.0061 16.1 0.1 0.031 13.9 0.0 2.3 2 0 0 2 2 2 1 F-box domain MMR_HSR1 PF01926.18 EAU92006.2 - 4.4e-11 42.7 0.1 7.8e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU92006.2 - 3.2e-07 29.6 0.1 3.2e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EAU92006.2 - 3.8e-07 30.0 0.0 8.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EAU92006.2 - 1.4e-06 28.7 0.1 3.9e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EAU92006.2 - 8e-06 25.3 0.1 3e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Ras family FtsK_SpoIIIE PF01580.13 EAU92006.2 - 1.4e-05 24.6 0.0 0.00078 18.9 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 EAU92006.2 - 8.9e-05 21.7 0.1 0.00015 21.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EAU92006.2 - 0.00063 18.6 0.0 0.00089 18.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.13 EAU92006.2 - 0.0022 17.0 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 EAU92006.2 - 0.0033 17.7 0.1 0.0073 16.5 0.1 1.5 1 1 0 1 1 1 1 ABC transporter FeoB_N PF02421.13 EAU92006.2 - 0.0052 16.0 0.1 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_10 PF12846.2 EAU92006.2 - 0.0063 15.9 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 EAU92006.2 - 0.016 15.4 0.0 0.062 13.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 EAU92006.2 - 0.022 14.8 0.3 0.075 13.1 0.2 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EAU92006.2 - 0.092 12.4 0.0 16 5.1 0.0 2.3 2 1 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EAU92006.2 - 0.25 11.6 2.9 0.91 9.8 2.0 2.2 1 1 0 1 1 1 0 AAA domain COesterase PF00135.23 EAU92008.2 - 3.2e-82 276.9 0.0 3.8e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU92008.2 - 4.3e-07 29.7 0.1 4.2e-06 26.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU92008.2 - 1.3e-05 24.9 0.0 2.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU92008.2 - 0.0045 16.2 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family F-box PF00646.28 EAU92009.2 - 4.1e-06 26.2 0.0 8.7e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92009.2 - 2e-05 24.1 0.1 5e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like Cu-oxidase PF00394.17 EAU92011.2 - 1.9e-41 141.6 0.0 7.6e-38 129.9 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU92011.2 - 1.2e-34 118.5 1.4 2.5e-33 114.3 0.6 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU92011.2 - 1.3e-34 118.6 7.4 2.6e-31 107.9 0.2 3.2 2 1 0 2 2 2 2 Multicopper oxidase F-box PF00646.28 EAU92013.2 - 1.9e-05 24.1 0.0 4.7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92013.2 - 2.1e-05 24.1 0.1 5.9e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like NAD_binding_5 PF07994.7 EAU92014.1 - 1.8e-108 362.4 0.0 2.3e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EAU92014.1 - 1.9e-43 146.8 0.1 4.4e-43 145.6 0.0 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Bromodomain PF00439.20 EAU92016.1 - 7.1e-22 77.1 0.3 1.6e-21 75.9 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EAU92016.1 - 7.9e-07 28.7 0.0 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated K_channel_TID PF07941.6 EAU92016.1 - 0.34 11.1 0.0 0.34 11.1 0.0 4.8 5 0 0 5 5 5 0 Potassium channel Kv1.4 tandem inactivation domain NIF PF03031.13 EAU92017.1 - 1.6e-37 128.5 0.0 2.5e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Foie-gras_1 PF11817.3 EAU92017.1 - 0.0035 16.8 0.4 0.0035 16.8 0.3 1.8 3 0 0 3 3 3 1 Foie gras liver health family 1 DUF1206 PF06724.6 EAU92017.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) KIAA1430 PF13879.1 EAU92017.1 - 0.048 14.0 0.5 0.12 12.7 0.4 1.6 1 0 0 1 1 1 0 KIAA1430 homologue Lipase_GDSL PF00657.17 EAU92018.1 - 6.8e-14 52.2 0.1 9.6e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EAU92018.1 - 8.1e-07 29.3 0.1 1.4e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.13 EAU92019.1 - 1.6e-08 34.0 1.4 2.7e-08 33.3 1.0 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain RibD_C PF01872.12 EAU92019.1 - 0.0062 16.1 0.9 1.4 8.4 0.0 2.9 1 1 1 2 2 2 2 RibD C-terminal domain CBM_1 PF00734.13 EAU92020.1 - 1.7e-07 30.7 5.4 2.6e-07 30.1 3.7 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_1 PF00734.13 EAU92021.1 - 2.2e-09 36.8 1.2 3.5e-09 36.1 0.9 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU92021.1 - 0.14 12.2 0.2 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Toxin 7 Collagen PF01391.13 EAU92021.1 - 0.3 10.6 6.4 0.045 13.3 1.7 1.7 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) CBM_1 PF00734.13 EAU92022.1 - 1.8e-10 40.3 1.3 3.2e-10 39.5 0.9 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain SOBP PF15279.1 EAU92022.1 - 8.4 6.6 9.4 7.9 6.7 6.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CBM_1 PF00734.13 EAU92023.2 - 8.7e-09 34.8 6.8 1.4e-08 34.2 4.7 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EAU92023.2 - 0.41 10.7 2.4 0.71 9.9 1.6 1.5 1 0 0 1 1 1 0 Toxin 7 DDE_3 PF13358.1 EAU92024.2 - 5.8e-13 48.8 0.0 2.5e-12 46.7 0.0 2.1 2 1 0 2 2 2 1 DDE superfamily endonuclease CBM_1 PF00734.13 EAU92025.1 - 9.5e-07 28.3 0.5 1.5e-06 27.7 0.3 1.3 1 0 0 1 1 1 1 Fungal cellulose binding domain F-box PF00646.28 EAU92026.1 - 0.0022 17.5 0.7 0.016 14.8 0.0 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EAU92026.1 - 0.014 15.1 0.1 0.074 12.7 0.0 2.2 2 0 0 2 2 2 0 F-box-like SR-25 PF10500.4 EAU92026.1 - 0.53 9.7 3.2 0.88 9.0 2.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CENP-B_dimeris PF09026.5 EAU92026.1 - 0.7 10.1 6.0 18 5.6 3.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RhoGAP PF00620.22 EAU92027.2 - 7.7e-42 142.4 0.0 2.2e-41 141.0 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 EAU92027.2 - 5.1e-12 45.8 0.0 9.5e-09 35.2 0.0 3.0 3 0 0 3 3 3 2 RasGEF domain PH PF00169.24 EAU92027.2 - 2.2e-06 27.8 0.0 0.0029 17.8 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EAU92027.2 - 4.1e-06 26.9 0.0 1.7e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain RasGEF_N PF00618.15 EAU92027.2 - 0.0066 16.5 0.0 0.083 13.0 0.0 3.0 2 1 0 2 2 2 1 RasGEF N-terminal motif Ribosomal_L37 PF08561.5 EAU92028.1 - 1.6e-20 72.4 0.1 2.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Tyrosinase PF00264.15 EAU92029.1 - 5.3e-36 124.8 0.0 7.5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyrosinase PF00264.15 EAU92030.2 - 2e-31 109.9 0.0 3.1e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.14 EAU92031.2 - 8e-13 48.1 0.4 3.9e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EAU92031.2 - 6.5e-09 35.1 6.8 2.5e-05 23.3 3.3 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU92031.2 - 1.7e-07 31.1 1.2 4.4e-07 29.8 0.8 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EAU92031.2 - 1.2e-06 27.2 0.2 3.7e-06 25.6 0.1 1.7 1 1 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EAU92031.2 - 2.7e-06 26.5 0.9 0.002 17.1 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Amino_oxidase PF01593.19 EAU92031.2 - 1.7e-05 24.0 1.2 0.12 11.4 0.3 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EAU92031.2 - 2.2e-05 23.2 1.7 0.031 12.9 1.5 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EAU92031.2 - 0.0001 22.6 1.9 0.00026 21.3 0.6 2.3 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU92031.2 - 0.00028 20.9 0.2 0.00078 19.5 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU92031.2 - 0.00041 20.2 1.1 0.00097 19.0 0.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EAU92031.2 - 0.00055 19.1 0.4 0.0011 18.0 0.3 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EAU92031.2 - 0.0013 17.7 2.6 0.0032 16.4 1.8 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EAU92031.2 - 0.0016 17.3 5.2 0.0029 16.4 3.6 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EAU92031.2 - 0.0031 16.6 0.4 0.0062 15.6 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EAU92031.2 - 0.014 15.0 2.0 0.23 11.1 0.8 2.6 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Rossmann-like PF10727.4 EAU92031.2 - 0.025 14.2 0.2 0.088 12.5 0.0 2.0 2 0 0 2 2 2 0 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EAU92031.2 - 0.055 12.8 0.9 0.099 12.0 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EAU92031.2 - 0.15 11.6 1.0 0.3 10.7 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cu-oxidase PF00394.17 EAU92032.2 - 2.2e-45 154.3 0.0 5.1e-41 140.2 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU92032.2 - 3.1e-40 136.5 1.5 1.8e-37 127.6 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU92032.2 - 6.8e-37 126.0 5.7 5.1e-34 116.7 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cyclin_N PF00134.18 EAU92037.2 - 7.9e-12 44.8 0.0 1.3e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EAU92037.2 - 0.0026 18.1 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin Dmrt1 PF12374.3 EAU92037.2 - 0.051 13.9 5.1 0.11 12.8 3.5 1.5 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 F-box PF00646.28 EAU92038.2 - 4.9e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92038.2 - 0.006 16.2 0.1 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF4568 PF15132.1 EAU92038.2 - 0.021 14.0 0.1 4.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4568) DUF4180 PF13788.1 EAU92039.2 - 0.1 12.2 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4180) Antimicrobial10 PF08105.6 EAU92040.2 - 0.023 14.3 0.2 0.065 12.8 0.1 1.7 1 0 0 1 1 1 0 Metchnikowin family KR PF08659.5 EAU92048.1 - 2.3e-07 30.6 0.0 5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EAU92048.1 - 2.4e-07 30.8 0.1 6.2e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Rtf2 PF04641.7 EAU92048.1 - 0.073 12.2 4.3 0.13 11.4 3.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Asp-B-Hydro_N PF05279.6 EAU92048.1 - 0.27 11.0 7.1 0.41 10.4 4.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PRA1 PF03208.14 EAU92048.1 - 0.31 10.3 1.2 9.2 5.5 0.2 2.4 2 0 0 2 2 2 0 PRA1 family protein RPEL PF02755.10 EAU92049.2 - 0.27 10.6 1.6 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 RPEL repeat IncA PF04156.9 EAU92050.1 - 0.0006 19.4 7.1 0.00083 19.0 4.1 1.8 2 0 0 2 2 1 1 IncA protein Spc7 PF08317.6 EAU92050.1 - 0.0031 16.2 4.0 0.0051 15.5 2.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EAU92050.1 - 0.0034 17.1 2.6 0.0066 16.1 1.8 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EAU92050.1 - 0.0044 16.2 2.4 0.0091 15.2 0.2 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EAU92050.1 - 0.0045 14.9 0.9 0.0061 14.4 0.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF869 PF05911.6 EAU92050.1 - 0.0078 14.5 3.3 0.012 13.8 2.3 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF1192 PF06698.6 EAU92050.1 - 0.0086 15.8 2.9 1.7 8.4 0.8 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1192) ERM PF00769.14 EAU92050.1 - 0.013 15.0 6.9 0.019 14.5 4.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PTRF_SDPR PF15237.1 EAU92050.1 - 0.013 14.8 1.2 0.025 13.9 0.3 1.8 1 1 0 1 1 1 0 PTRF/SDPR family MAD PF05557.8 EAU92050.1 - 0.015 13.4 6.2 0.024 12.7 4.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein APG6 PF04111.7 EAU92050.1 - 0.027 13.5 4.8 0.053 12.5 3.3 1.5 2 0 0 2 2 1 0 Autophagy protein Apg6 GAS PF13851.1 EAU92050.1 - 0.038 13.1 6.2 0.46 9.6 4.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2681 PF10883.3 EAU92050.1 - 0.047 13.9 0.3 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Tropomyosin_1 PF12718.2 EAU92050.1 - 0.05 13.4 7.9 0.092 12.5 5.5 1.4 1 0 0 1 1 1 0 Tropomyosin like Mnd1 PF03962.10 EAU92050.1 - 0.06 13.0 4.3 0.13 11.9 3.0 1.6 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.9 EAU92050.1 - 0.062 13.2 2.5 0.13 12.1 1.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TBPIP PF07106.8 EAU92050.1 - 0.079 12.5 4.2 0.28 10.7 2.5 1.9 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4200 PF13863.1 EAU92050.1 - 0.08 12.8 8.2 0.29 11.0 5.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 EAU92050.1 - 0.099 11.0 1.7 0.15 10.4 1.2 1.2 1 0 0 1 1 1 0 AAA domain DUF2353 PF09789.4 EAU92050.1 - 0.11 11.7 6.3 0.83 8.8 3.5 2.2 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.3 EAU92050.1 - 0.15 11.9 9.3 0.41 10.5 6.4 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EAU92050.1 - 0.17 11.7 3.5 0.18 11.6 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tht1 PF04163.7 EAU92050.1 - 0.17 10.2 0.3 0.26 9.6 0.2 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein CCDC155 PF14662.1 EAU92050.1 - 0.19 11.3 11.2 0.47 10.0 7.7 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF3552 PF12072.3 EAU92050.1 - 0.19 10.8 9.8 0.38 9.9 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DivIVA PF05103.8 EAU92050.1 - 0.21 11.6 4.9 3.3 7.7 4.1 2.3 2 0 0 2 2 2 0 DivIVA protein ATG16 PF08614.6 EAU92050.1 - 0.28 10.9 11.7 0.19 11.5 4.5 2.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EAU92050.1 - 0.3 10.9 10.5 0.54 10.1 5.6 2.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 EAU92050.1 - 0.44 8.9 1.8 0.76 8.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF724 PF05266.9 EAU92050.1 - 0.44 10.1 3.5 0.92 9.0 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.17 EAU92050.1 - 0.81 9.7 6.0 4.4 7.3 1.1 2.7 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 EAU92050.1 - 0.85 9.4 11.6 0.25 11.1 4.5 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.7 EAU92050.1 - 0.96 9.2 8.9 0.15 11.8 2.3 2.5 2 1 1 3 3 2 0 Plant protein of unknown function (DUF641) bZIP_2 PF07716.10 EAU92050.1 - 1 9.2 10.2 1.2 9.0 1.3 2.9 3 0 0 3 3 2 0 Basic region leucine zipper Fib_alpha PF08702.5 EAU92050.1 - 1.3 9.1 5.5 2.6 8.1 1.0 2.5 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family DMPK_coil PF08826.5 EAU92050.1 - 1.5 8.7 13.6 0.079 12.8 1.7 3.7 3 1 1 4 4 3 0 DMPK coiled coil domain like Prefoldin PF02996.12 EAU92050.1 - 1.8 8.2 6.6 3.3 7.3 0.3 3.0 2 1 1 3 3 3 0 Prefoldin subunit Nup88 PF10168.4 EAU92050.1 - 2 6.1 6.3 3.1 5.5 3.0 2.1 3 0 0 3 3 3 0 Nuclear pore component DUF904 PF06005.7 EAU92050.1 - 3.2 8.1 6.9 9.5 6.5 3.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Atg14 PF10186.4 EAU92050.1 - 5.1 5.9 10.9 4.2 6.2 6.1 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EAU92050.1 - 6.4 6.3 7.1 4.9 6.7 0.9 3.0 2 1 1 3 3 3 0 Septum formation initiator FlxA PF14282.1 EAU92050.1 - 6.7 6.7 11.1 0.43 10.5 3.5 2.1 3 0 0 3 3 2 0 FlxA-like protein CysG_dimeriser PF10414.4 EAU92052.2 - 8.2e-05 22.0 0.0 4 6.9 0.0 4.7 5 0 0 5 5 5 2 Sirohaem synthase dimerisation region DUF1323 PF07037.6 EAU92052.2 - 0.00085 19.4 0.2 23 5.1 0.0 4.2 2 2 3 5 5 5 2 Putative transcription regulator (DUF1323) DUF630 PF04783.7 EAU92052.2 - 0.16 11.9 0.0 91 3.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF630) DUF1691 PF07950.6 EAU92053.2 - 0.12 12.2 0.2 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Haemadin PF09065.5 EAU92055.1 - 1.9 8.1 5.3 0.84 9.2 1.1 2.3 2 0 0 2 2 2 0 Haemadin EphA2_TM PF14575.1 EAU92057.2 - 0.16 12.4 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ank PF00023.25 EAU92058.2 - 2.7e-36 121.5 0.1 0.00014 21.4 0.0 8.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 EAU92058.2 - 2.2e-35 119.8 1.7 1.2e-07 31.7 0.0 6.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU92058.2 - 6.5e-35 119.3 0.0 6.7e-15 55.2 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU92058.2 - 1.8e-31 107.9 0.5 7.1e-09 35.9 0.0 5.4 6 0 0 6 6 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU92058.2 - 1.3e-24 83.8 0.0 0.026 14.7 0.0 8.1 7 0 0 7 7 7 6 Ankyrin repeat NACHT PF05729.7 EAU92058.2 - 1.1e-05 25.1 0.1 2.8e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EAU92058.2 - 3.6e-05 23.8 0.1 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF463 PF04317.7 EAU92058.2 - 0.012 14.2 0.0 0.2 10.1 0.0 2.2 2 0 0 2 2 2 0 YcjX-like family, DUF463 Se-cys_synth_N PF12390.3 EAU92058.2 - 0.017 15.2 2.2 17 5.5 0.4 4.9 3 1 0 3 3 3 0 Selenocysteine synthase N terminal AAA_16 PF13191.1 EAU92058.2 - 0.02 14.9 0.1 0.069 13.1 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EAU92058.2 - 0.02 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAU92058.2 - 0.036 13.8 0.0 0.14 11.8 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EAU92058.2 - 0.044 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 EAU92058.2 - 0.054 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EAU92058.2 - 0.065 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EAU92058.2 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Keratin_matx PF04579.7 EAU92058.2 - 0.19 12.0 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein Ank_2 PF12796.2 EAU92059.2 - 1.8e-90 297.4 3.2 3.2e-15 56.2 0.0 7.3 2 1 4 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 EAU92059.2 - 1.3e-66 217.2 26.9 0.00066 19.3 0.0 16.9 14 3 3 17 17 17 14 Ankyrin repeat Ank_5 PF13857.1 EAU92059.2 - 1.4e-65 215.8 20.8 6.9e-07 29.3 0.0 15.4 2 1 13 15 15 15 15 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU92059.2 - 1.4e-59 192.0 1.7 0.013 15.6 0.0 16.4 16 0 0 16 16 16 13 Ankyrin repeat Ank_4 PF13637.1 EAU92059.2 - 4.1e-37 125.9 4.5 1.2e-07 32.0 0.0 11.2 9 2 0 11 11 11 8 Ankyrin repeats (many copies) Imm29 PF15575.1 EAU92059.2 - 0.0014 18.2 0.0 9.6 5.7 0.0 4.6 2 1 3 6 6 6 2 Immunity protein 29 E1_dh PF00676.15 EAU92059.2 - 0.057 12.1 9.0 8.9 4.9 0.0 5.2 3 1 3 6 6 6 0 Dehydrogenase E1 component NACHT PF05729.7 EAU92059.2 - 0.072 12.7 0.1 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Ank PF00023.25 EAU92062.2 - 4.2e-81 262.9 5.7 1.3e-06 27.8 0.0 13.5 13 0 0 13 13 13 11 Ankyrin repeat Ank_2 PF12796.2 EAU92062.2 - 3.1e-75 248.5 0.0 6.9e-14 51.9 0.0 7.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU92062.2 - 8.6e-74 242.7 0.6 1.5e-11 44.4 0.0 11.1 7 3 4 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU92062.2 - 2.2e-72 237.4 9.0 4.5e-11 42.6 0.0 13.2 3 1 10 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU92062.2 - 5.4e-62 199.5 0.1 0.00033 20.5 0.0 13.3 12 0 0 12 12 12 11 Ankyrin repeat NapD PF03927.8 EAU92062.2 - 7.3e-07 28.9 9.3 3.6 7.5 0.0 9.0 3 1 7 11 11 11 1 NapD protein NACHT PF05729.7 EAU92062.2 - 3.9e-06 26.6 0.1 1.4e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU92062.2 - 0.00016 21.7 0.2 0.00045 20.2 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EAU92062.2 - 0.00055 20.0 0.0 0.0022 18.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU92062.2 - 0.00089 18.9 0.7 0.087 12.5 0.0 3.8 4 0 0 4 4 3 1 Part of AAA domain AAA_14 PF13173.1 EAU92062.2 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EAU92062.2 - 0.021 14.2 0.1 0.089 12.2 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EAU92062.2 - 0.049 13.3 0.1 0.44 10.2 0.0 2.7 2 1 0 3 3 3 0 NTPase AAA_17 PF13207.1 EAU92062.2 - 0.075 13.8 0.1 0.29 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF503 PF04456.7 EAU92062.2 - 0.077 12.6 0.1 4.1 7.0 0.0 3.5 4 1 1 5 5 4 0 Protein of unknown function (DUF503) Fucokinase PF07959.7 EAU92062.2 - 0.089 11.3 0.0 4.4 5.7 0.0 3.2 4 0 0 4 4 4 0 L-fucokinase Arch_ATPase PF01637.13 EAU92062.2 - 0.16 11.6 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase DUF1070 PF06376.7 EAU92062.2 - 0.67 9.8 5.8 0.43 10.4 0.1 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF1070) Ribosomal_L16 PF00252.13 EAU92064.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e Voldacs PF03517.8 EAU92065.1 - 0.023 14.5 0.2 0.053 13.3 0.1 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Rep_4 PF05797.6 EAU92065.1 - 0.03 13.0 0.1 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Nucleoplasmin PF03066.10 EAU92065.1 - 0.3 10.6 7.8 0.59 9.6 5.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EAU92065.1 - 0.74 9.0 2.5 1.4 8.0 1.7 1.4 1 0 0 1 1 1 0 NOA36 protein DUF3813 PF12758.2 EAU92066.2 - 0.0017 18.4 3.0 0.36 10.9 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3813) DUF240 PF03086.9 EAU92068.2 - 0.01 15.4 0.1 6.2 6.4 0.0 2.4 2 0 0 2 2 2 0 MG032/MG096/MG288 family 2 HEAT_EZ PF13513.1 EAU92069.1 - 0.0001 22.6 0.2 0.098 13.1 0.0 4.4 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.17 EAU92069.1 - 0.00076 19.3 1.6 0.0018 18.2 0.0 2.6 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EAU92069.1 - 0.0045 17.2 0.1 0.028 14.6 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EAU92069.1 - 0.027 14.8 0.0 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region WLM PF08325.5 EAU92069.1 - 0.084 12.7 0.1 15 5.3 0.1 2.3 2 0 0 2 2 2 0 WLM domain HEAT PF02985.17 EAU92070.1 - 0.0024 17.7 0.0 3.4 7.9 0.0 3.3 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.1 EAU92070.1 - 0.3 11.6 4.5 0.38 11.3 0.1 3.4 5 0 0 5 5 5 0 HEAT-like repeat Peptidase_M43 PF05572.8 EAU92072.2 - 1.8e-16 60.1 0.0 2.9e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU92072.2 - 5.1e-09 36.3 1.6 9.7e-09 35.4 1.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU92072.2 - 3.9e-07 30.6 0.7 9.2e-07 29.4 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU92072.2 - 2.4e-05 24.4 0.8 4.6e-05 23.5 0.5 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU92072.2 - 0.015 14.8 2.8 0.053 13.0 1.9 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU92072.2 - 0.03 14.0 0.0 0.054 13.2 0.0 1.3 1 1 0 1 1 1 0 Matrixin Minor_capsid_3 PF12691.2 EAU92072.2 - 0.15 11.7 0.1 0.33 10.6 0.1 1.5 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Tyrosinase PF00264.15 EAU92074.2 - 1.3e-27 97.3 2.3 2.3e-27 96.6 1.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-MYND PF01753.13 EAU92074.2 - 2e-08 33.9 11.9 4.6e-08 32.7 8.3 1.6 1 0 0 1 1 1 1 MYND finger HpaB PF03241.8 EAU92074.2 - 0.14 11.0 0.3 0.26 10.1 0.0 1.5 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase C terminal zf-Mss51 PF13824.1 EAU92074.2 - 4.2 7.3 7.4 5.1 7.0 3.9 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Tyrosinase PF00264.15 EAU92075.1 - 2.3e-31 109.7 4.1 3.9e-31 108.9 2.6 1.4 1 1 0 1 1 1 1 Common central domain of tyrosinase Cmc1 PF08583.5 EAU92076.2 - 0.021 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Grp1_Fun34_YaaH PF01184.14 EAU92077.1 - 2e-40 138.3 12.7 2.3e-40 138.1 8.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BTB PF00651.26 EAU92079.1 - 0.0048 16.8 0.2 0.029 14.3 0.2 2.1 1 1 0 1 1 1 1 BTB/POZ domain DUF4335 PF14233.1 EAU92079.1 - 0.036 13.5 0.0 0.036 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Glyco_hydro_65m PF03632.10 EAU92083.1 - 0.031 12.9 0.1 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Cu-oxidase PF00394.17 EAU92088.2 - 6.8e-44 149.5 0.0 5.2e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU92088.2 - 1.5e-34 118.4 2.2 5.9e-33 113.2 0.0 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU92088.2 - 2.3e-32 111.1 0.1 8.8e-32 109.3 0.1 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EAU92090.2 - 4.7e-44 150.1 0.0 3.5e-42 143.9 0.0 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU92090.2 - 3.4e-37 126.7 0.1 1.4e-36 124.7 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU92090.2 - 2.1e-35 121.2 4.5 1.2e-33 115.5 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase zf-C2H2 PF00096.21 EAU92092.1 - 2.4e-05 24.4 0.9 0.17 12.2 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU92092.1 - 0.00058 20.0 1.4 0.18 12.2 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU92092.1 - 0.0023 18.0 1.5 0.12 12.5 0.1 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EAU92092.1 - 0.043 13.9 1.1 0.53 10.4 0.8 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Cu-oxidase PF00394.17 EAU92093.2 - 5e-50 169.5 0.0 2.8e-47 160.5 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU92093.2 - 1.6e-38 131.3 0.9 1.6e-36 124.8 0.1 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU92093.2 - 1.6e-26 92.3 0.1 6.5e-24 83.9 0.0 3.3 3 0 0 3 3 3 1 Multicopper oxidase PEMT PF04191.8 EAU92095.1 - 5.5e-12 45.7 1.2 3.4e-10 39.9 0.4 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EAU92095.1 - 6.8e-12 45.4 0.3 2.4e-11 43.6 0.1 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EAU92095.1 - 4.4e-05 22.1 0.7 6.5e-05 21.6 0.5 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1996 PF09362.5 EAU92096.2 - 3.1e-81 272.4 0.0 3.7e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) APH PF01636.18 EAU92097.2 - 0.0018 18.0 0.1 0.005 16.6 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAU92097.2 - 0.0026 16.9 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Glyco_transf_15 PF01793.11 EAU92099.2 - 1e-57 195.5 1.6 5.3e-40 137.3 0.0 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase PADR1 PF08063.7 EAU92101.2 - 0.017 14.5 4.8 0.5 9.8 0.0 3.0 3 0 0 3 3 3 0 PADR1 (NUC008) domain RecR PF02132.10 EAU92101.2 - 0.058 12.8 1.2 9 5.8 0.1 2.6 2 0 0 2 2 2 0 RecR protein zf-dskA_traR PF01258.12 EAU92101.2 - 0.44 10.3 5.4 0.51 10.1 0.3 3.0 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger OrfB_Zn_ribbon PF07282.6 EAU92101.2 - 2.8 7.6 9.7 8.2 6.1 0.1 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-HIT PF04438.11 EAU92101.2 - 5.9 6.6 6.8 26 4.5 0.1 3.1 3 0 0 3 3 3 0 HIT zinc finger Abhydrolase_6 PF12697.2 EAU92103.2 - 2e-29 103.1 1.2 2.5e-29 102.7 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU92103.2 - 5e-17 61.9 0.0 1.2e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU92103.2 - 1e-16 61.2 0.0 7.7e-12 45.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Ndr PF03096.9 EAU92103.2 - 4.6e-06 25.3 0.0 7.6e-06 24.6 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EAU92103.2 - 1.9e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 EAU92103.2 - 0.045 13.2 0.0 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 Serine hydrolase (FSH1) UPF0227 PF05728.7 EAU92103.2 - 0.082 12.6 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DLH PF01738.13 EAU92103.2 - 0.12 11.5 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family CFEM PF05730.6 EAU92108.1 - 5.4e-07 29.3 10.7 9.2e-07 28.6 7.4 1.3 1 0 0 1 1 1 1 CFEM domain AF-4 PF05110.8 EAU92108.1 - 0.061 11.2 18.7 0.08 10.8 12.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pol_alpha_B_N PF08418.5 EAU92108.1 - 5.6 6.4 7.8 7.7 5.9 5.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 EAU92108.1 - 7.7 5.8 13.7 9.1 5.5 9.5 1.1 1 0 0 1 1 1 0 Vta1 like F-box-like PF12937.2 EAU92111.1 - 2.5e-09 36.7 0.0 8.7e-05 22.1 0.0 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EAU92111.1 - 0.023 14.3 0.9 5.5 6.7 0.1 2.7 2 0 0 2 2 2 0 F-box domain DUF1996 PF09362.5 EAU92114.1 - 4e-84 281.9 0.0 5e-84 281.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EAU92114.1 - 1.5e-11 43.7 12.4 1.5e-11 43.7 8.6 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain F-box-like PF12937.2 EAU92117.2 - 0.00018 21.1 0.0 0.00084 19.0 0.0 2.2 1 1 0 1 1 1 1 F-box-like AhpC-TSA_2 PF13911.1 EAU92121.2 - 1.3e-22 79.8 0.0 2.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EAU92121.2 - 1.7e-07 30.9 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EAU92121.2 - 7.9e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF899 PF05988.7 EAU92121.2 - 5.6e-05 22.6 0.0 8.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) MIP-T3 PF10243.4 EAU92122.1 - 0.017 13.6 40.8 0.026 13.0 28.3 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1981 PF09324.5 EAU92122.1 - 0.024 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) DUF1930 PF09122.5 EAU92123.2 - 0.045 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) F-box-like PF12937.2 EAU92128.1 - 0.00082 19.0 0.0 0.0061 16.2 0.0 2.4 1 1 0 1 1 1 1 F-box-like Dus PF01207.12 EAU92129.1 - 1.9e-74 250.2 0.0 3e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 EAU92129.1 - 4.8e-05 22.5 0.0 0.0001 21.4 0.0 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOBP PF15279.1 EAU92129.1 - 0.0047 17.3 3.9 0.0084 16.5 2.7 1.3 1 0 0 1 1 1 1 Sine oculis-binding protein SOR_SNZ PF01680.12 EAU92129.1 - 0.0065 16.0 1.6 0.025 14.1 0.0 2.5 2 1 1 3 3 3 1 SOR/SNZ family His_biosynth PF00977.16 EAU92129.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein CAF-1_p150 PF11600.3 EAU92130.2 - 0.0086 15.4 42.7 0.012 14.9 29.6 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal NAAA-beta PF15508.1 EAU92130.2 - 0.056 13.7 0.1 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DNA_methylase PF00145.12 EAU92130.2 - 0.15 11.1 9.5 0.17 10.9 6.6 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Bacillus_HBL PF05791.6 EAU92130.2 - 0.2 10.9 4.0 0.36 10.1 2.8 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) GAGA_bind PF06217.7 EAU92130.2 - 1.7 8.5 14.4 2.6 7.9 10.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family SprA-related PF12118.3 EAU92130.2 - 1.7 7.8 17.8 2.4 7.4 12.4 1.2 1 0 0 1 1 1 0 SprA-related family ING PF12998.2 EAU92130.2 - 1.8 8.8 16.0 1.8 8.9 0.2 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Neur_chan_memb PF02932.11 EAU92130.2 - 3 7.6 10.4 4.1 7.2 7.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.8 EAU92130.2 - 6.6 5.8 30.9 11 5.1 21.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.6 EAU92130.2 - 7.6 6.2 29.0 11 5.8 20.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spc7 PF08317.6 EAU92130.2 - 8.6 4.9 31.4 2.3 6.8 12.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EAU92132.2 - 6.9 4.3 7.0 11 3.7 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tetraspannin PF00335.15 EAU92135.1 - 2.6e-15 56.3 8.1 3.6e-15 55.8 5.6 1.1 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 EAU92136.1 - 7.4e-08 32.3 10.8 7.4e-08 32.3 7.5 2.2 1 1 1 2 2 2 1 Membrane-associating domain Claudin_3 PF06653.6 EAU92136.1 - 0.023 14.4 1.2 0.023 14.4 0.8 2.1 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Cpn60_TCP1 PF00118.19 EAU92138.2 - 1.3e-137 459.3 2.4 1.6e-137 459.0 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F-box-like PF12937.2 EAU92139.1 - 2.5e-05 23.9 0.4 0.00027 20.6 0.0 2.9 3 1 0 3 3 3 1 F-box-like DUF3760 PF12586.3 EAU92139.1 - 0.085 12.7 0.1 0.7 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) F-box-like PF12937.2 EAU92140.2 - 0.0071 16.0 0.3 0.038 13.7 0.2 2.3 2 0 0 2 2 2 1 F-box-like GMC_oxred_N PF00732.14 EAU92145.2 - 1.3e-46 159.1 0.9 1.5e-45 155.6 0.7 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EAU92145.2 - 4.3e-33 114.6 0.0 9.8e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase CBM_21 PF03370.8 EAU92149.1 - 5e-17 61.9 1.2 2.7e-13 49.8 0.0 3.3 2 1 0 2 2 2 2 Putative phosphatase regulatory subunit DIOX_N PF14226.1 EAU92150.1 - 5e-16 59.2 0.0 7.8e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EAU92150.1 - 4.5e-14 52.5 0.0 7.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP11 PF06644.6 EAU92150.1 - 0.18 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein Bestrophin PF01062.16 EAU92151.2 - 5.9e-48 163.2 0.1 5.9e-28 97.6 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4598 PF15370.1 EAU92152.2 - 7.6e-12 45.5 7.2 3.1e-11 43.5 5.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) Macoilin PF09726.4 EAU92152.2 - 0.0094 14.2 8.1 0.0098 14.2 5.6 1.1 1 0 0 1 1 1 1 Transmembrane protein Flu_B_NS1 PF02942.9 EAU92152.2 - 0.12 11.2 0.1 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) RAP1 PF07218.6 EAU92152.2 - 0.13 10.3 10.5 0.16 10.0 7.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.8 EAU92152.2 - 0.3 8.8 22.6 0.02 12.7 11.8 1.8 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Apt1 PF10351.4 EAU92152.2 - 0.39 9.5 10.2 0.51 9.1 7.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dmrt1 PF12374.3 EAU92152.2 - 0.71 10.2 20.8 4.1 7.8 0.2 2.4 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 CDC45 PF02724.9 EAU92152.2 - 1.8 6.4 11.9 2.7 5.9 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Period_C PF12114.3 EAU92152.2 - 9.7 5.7 20.9 18 4.8 14.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Peptidase_C14 PF00656.17 EAU92153.2 - 9.5e-54 182.7 0.3 9.5e-54 182.7 0.2 1.8 2 1 0 2 2 2 1 Caspase domain TauD PF02668.11 EAU92154.1 - 1.6e-32 113.2 0.0 2.2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EAU92154.1 - 0.029 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 CsiD F-box PF00646.28 EAU92157.2 - 9.2e-09 34.7 0.6 1.9e-08 33.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92157.2 - 1.5e-06 27.8 2.0 4e-06 26.4 1.4 1.8 1 0 0 1 1 1 1 F-box-like DUF3796 PF12676.2 EAU92158.2 - 0.18 12.0 2.8 1.3 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) 60KD_IMP PF02096.15 EAU92158.2 - 0.21 11.2 3.1 0.7 9.5 1.8 2.1 2 1 0 2 2 2 0 60Kd inner membrane protein 5TM-5TMR_LYT PF07694.7 EAU92158.2 - 0.95 8.7 9.5 1.4 8.1 6.5 1.4 1 1 0 1 1 1 0 5TMR of 5TMR-LYT DctQ PF04290.7 EAU92158.2 - 1.8 8.3 11.6 0.15 11.8 0.6 2.6 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF983 PF06170.7 EAU92158.2 - 2.6 8.2 6.4 2.8 8.1 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Rifin_STEVOR PF02009.11 EAU92159.2 - 0.086 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family CDP-OH_P_transf PF01066.16 EAU92160.1 - 1.5e-16 60.5 1.4 1.5e-16 60.5 0.9 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase F-box PF00646.28 EAU92162.2 - 0.00089 18.8 5.4 0.0014 18.2 0.7 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EAU92162.2 - 1.1 9.0 11.2 0.64 9.7 1.4 2.8 2 1 0 2 2 2 0 F-box-like F-box PF00646.28 EAU92163.2 - 2.7e-05 23.6 0.6 5.7e-05 22.6 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92163.2 - 0.0066 16.1 2.2 0.013 15.2 1.5 1.5 1 0 0 1 1 1 1 F-box-like MARVEL PF01284.18 EAU92165.1 - 1.2e-09 38.1 21.3 1.4e-09 37.8 14.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain NKAIN PF05640.9 EAU92165.1 - 5.9 5.7 13.1 0.22 10.4 1.6 2.2 1 1 1 2 2 2 0 Na,K-Atpase Interacting protein Lipase_GDSL_2 PF13472.1 EAU92167.1 - 3.2e-18 66.5 3.8 1e-17 64.8 2.6 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU92167.1 - 9.4e-17 61.6 1.8 1.4e-16 61.0 1.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 EAU92167.1 - 1.5e-15 56.5 9.1 1.5e-15 56.5 6.3 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_GDSL_3 PF14606.1 EAU92167.1 - 0.00088 19.0 0.2 0.0053 16.5 0.1 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Abhydrolase_6 PF12697.2 EAU92171.2 - 1.2e-10 41.7 0.0 1.6e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box-like PF12937.2 EAU92172.2 - 9.5e-05 22.0 1.7 0.00022 20.8 1.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92172.2 - 0.0013 18.3 1.6 0.0029 17.2 1.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92173.2 - 6.5e-06 25.7 2.9 1.2e-05 24.8 2.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92173.2 - 0.0014 18.1 0.6 0.003 17.1 0.4 1.5 1 0 0 1 1 1 1 F-box domain Peptidase_C14 PF00656.17 EAU92175.2 - 2e-63 214.3 0.0 2.6e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Histone PF00125.19 EAU92176.1 - 4e-30 103.7 0.8 6.6e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU92176.1 - 1.3e-05 25.3 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAU92176.1 - 0.0008 19.4 1.7 0.0013 18.7 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EAU92176.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EAU92176.1 - 0.14 11.3 1.5 0.18 11.0 1.1 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T F-box-like PF12937.2 EAU92178.2 - 5.6e-07 29.1 2.2 1.1e-06 28.1 1.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92178.2 - 5.5e-05 22.6 2.4 0.00014 21.4 1.7 1.7 1 0 0 1 1 1 1 F-box domain DUF2849 PF11011.3 EAU92178.2 - 0.19 11.9 0.0 1 9.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2849) Fil_haemagg PF05594.9 EAU92179.1 - 9.3e-07 29.0 17.2 3.3e+02 1.6 11.9 4.4 1 1 0 1 1 1 0 Haemagluttinin repeat TruB_C PF09142.6 EAU92179.1 - 6.7e-06 25.6 0.2 51 3.6 0.0 7.3 2 2 8 10 10 10 0 tRNA Pseudouridine synthase II, C terminal Dockerin_1 PF00404.13 EAU92179.1 - 0.00036 20.0 18.8 4.4 7.1 0.1 8.7 9 0 0 9 9 9 1 Dockerin type I repeat Kelch_2 PF07646.10 EAU92179.1 - 0.0032 17.1 4.4 2.2e+02 1.8 0.0 7.3 9 0 0 9 9 9 0 Kelch motif DUF4035 PF13227.1 EAU92179.1 - 0.0064 15.8 0.7 2.7e+02 1.0 0.0 6.3 6 2 2 8 8 8 0 Protein of unknown function (DUF4035) YceI PF04264.8 EAU92179.1 - 0.03 14.2 0.1 6.6 6.6 0.0 2.8 1 1 2 3 3 3 0 YceI-like domain DUF4425 PF14466.1 EAU92179.1 - 0.38 10.8 5.2 22 5.2 0.1 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4425) HtaA PF04213.8 EAU92179.1 - 0.44 10.7 5.6 1.5e+02 2.5 3.1 3.7 1 1 1 2 2 2 0 Htaa Arteri_Gl PF00951.13 EAU92179.1 - 0.5 9.9 1.6 81 2.7 0.0 3.3 1 1 2 4 4 4 0 Arterivirus GL envelope glycoprotein MLANA PF14991.1 EAU92180.2 - 0.33 10.9 2.5 0.62 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein melan-A DUF1145 PF06611.7 EAU92180.2 - 0.36 10.4 11.1 0.91 9.2 1.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1145) F-box-like PF12937.2 EAU92183.1 - 1.7e-06 27.6 0.1 4.3e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92183.1 - 0.047 13.3 0.5 0.047 13.3 0.3 3.1 3 1 0 3 3 3 0 F-box domain AvrRpt-cleavage PF05627.6 EAU92183.1 - 0.13 11.2 0.2 0.86 8.7 0.0 2.2 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr HlyC PF02794.11 EAU92184.1 - 0.02 14.5 0.1 0.059 12.9 0.0 1.8 2 0 0 2 2 2 0 RTX toxin acyltransferase family DUF2992 PF11208.3 EAU92184.1 - 0.021 14.6 6.1 0.24 11.3 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) FlxA PF14282.1 EAU92184.1 - 4.6 7.2 13.1 0.47 10.4 1.4 2.5 2 0 0 2 2 2 0 FlxA-like protein DUF1777 PF08648.7 EAU92185.2 - 0.0025 17.5 32.0 0.0025 17.5 22.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) F-box PF00646.28 EAU92192.2 - 0.038 13.6 4.4 0.12 12.1 3.0 1.9 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EAU92192.2 - 1.1 9.0 6.1 0.17 11.6 1.2 2.1 2 0 0 2 2 2 0 F-box-like Rod-binding PF10135.4 EAU92197.1 - 0.0078 16.1 0.8 0.0078 16.1 0.6 1.9 2 1 0 2 2 2 1 Rod binding protein Ribosomal_L1 PF00687.16 EAU92198.2 - 2.2e-51 174.3 3.4 2.7e-51 174.0 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF848 PF05852.6 EAU92198.2 - 0.056 13.2 0.2 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) WSC PF01822.14 EAU92199.2 - 3.2e-40 135.9 19.7 5.3e-20 71.1 4.9 2.2 2 0 0 2 2 2 2 WSC domain Cauli_VI PF01693.11 EAU92203.1 - 1.1e-12 47.8 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Laps PF10169.4 EAU92203.1 - 0.03 14.5 0.3 0.043 14.0 0.2 1.2 1 0 0 1 1 1 0 Learning-associated protein F-box-like PF12937.2 EAU92205.1 - 0.00013 21.5 0.9 0.00028 20.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92205.1 - 0.00022 20.8 0.5 0.00047 19.7 0.3 1.6 1 0 0 1 1 1 1 F-box domain 3-alpha PF03475.9 EAU92205.1 - 0.099 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 3-alpha domain DUF676 PF05057.9 EAU92207.2 - 0.012 14.9 0.0 0.034 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.7 EAU92207.2 - 0.031 13.6 0.0 0.067 12.5 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.3 EAU92207.2 - 0.064 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) CBM_21 PF03370.8 EAU92208.2 - 6.1e-22 77.7 0.1 1.6e-20 73.1 0.1 2.2 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit Peptidase_M17 PF00883.16 EAU92210.2 - 2.9e-110 368.0 0.0 3.8e-110 367.6 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EAU92210.2 - 5.6e-14 51.9 0.2 1.1e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain CSTF2_hinge PF14327.1 EAU92212.2 - 6.8e-09 35.6 1.9 6.8e-09 35.6 1.3 2.5 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EAU92212.2 - 1.8e-05 23.9 0.1 1.8e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal DUF726 PF05277.7 EAU92213.2 - 1.7e-113 379.0 1.0 1.7e-113 379.0 0.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF726) VirJ PF06057.6 EAU92213.2 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) SRP14 PF02290.10 EAU92216.1 - 5e-24 84.0 0.0 1.2e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle 14kD protein TP_methylase PF00590.15 EAU92217.1 - 5.2e-40 137.4 0.3 8.9e-40 136.6 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EAU92217.1 - 7.7e-13 48.5 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EAU92217.1 - 2e-07 30.1 0.1 8.2e-06 25.0 0.0 2.4 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EAU92217.1 - 0.00014 20.7 0.1 0.00026 19.8 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF3328 PF11807.3 EAU92218.2 - 1.3e-17 64.1 0.1 1.7e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAT PF02259.18 EAU92222.1 - 0.017 14.1 0.1 0.097 11.6 0.0 2.0 2 0 0 2 2 2 0 FAT domain TPR_12 PF13424.1 EAU92222.1 - 0.17 11.8 6.2 3.3 7.7 0.4 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat OTT_1508_deam PF14441.1 EAU92223.2 - 9.5e-36 122.7 0.0 1.6e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase IRF PF00605.12 EAU92223.2 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor ubiquitin PF00240.18 EAU92224.1 - 6.3e-35 118.4 0.7 8.2e-35 118.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EAU92224.1 - 4.1e-31 106.3 8.4 6.5e-31 105.6 5.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EAU92224.1 - 5.9e-20 70.7 0.7 8.8e-20 70.1 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAU92224.1 - 8.1e-06 26.0 0.1 3e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAU92224.1 - 0.00018 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAU92224.1 - 0.008 16.0 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAU92224.1 - 0.017 15.3 0.1 0.017 15.2 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 EAU92224.1 - 0.22 11.3 1.6 0.84 9.4 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-DHHC PF01529.15 EAU92224.1 - 0.64 9.3 2.8 0.96 8.8 2.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Nop14 PF04147.7 EAU92225.1 - 0.47 8.3 9.2 0.66 7.8 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EAU92225.1 - 7.7 5.4 10.4 15 4.5 7.2 1.4 1 0 0 1 1 1 0 BUD22 COX5A PF02284.11 EAU92226.1 - 2.3e-40 136.9 0.2 3e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va bZIP_1 PF00170.16 EAU92227.1 - 5.1e-09 35.9 10.1 8.6e-09 35.2 7.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EAU92227.1 - 1.8e-07 30.8 13.1 3.5e-07 29.9 9.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EAU92227.1 - 0.014 15.6 6.9 0.014 15.6 4.8 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor OTT_1508_deam PF14441.1 EAU92228.2 - 8.4e-34 116.4 0.0 1.4e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase SelB-wing_3 PF09107.6 EAU92228.2 - 0.083 12.2 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix F-box-like PF12937.2 EAU92229.2 - 0.011 15.3 2.7 0.024 14.3 1.9 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EAU92229.2 - 0.03 14.0 2.3 0.065 12.9 1.6 1.6 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.20 EAU92231.2 - 2.2e-75 253.1 0.0 3e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92231.2 - 2.9e-39 134.7 0.0 4.3e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EAU92231.2 - 8.8e-06 25.1 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.6 EAU92231.2 - 8.8e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EAU92231.2 - 0.00012 21.1 0.0 0.00022 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU92231.2 - 0.0032 16.5 0.5 0.05 12.6 0.4 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.4 EAU92231.2 - 0.025 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EAU92231.2 - 0.084 12.5 3.6 0.18 11.5 0.3 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family TM231 PF10149.4 EAU92232.1 - 0.29 10.1 2.0 0.2 10.6 0.3 1.4 2 0 0 2 2 2 0 Transmembrane protein 231 BAF1_ABF1 PF04684.8 EAU92232.1 - 0.72 8.6 11.0 0.95 8.2 7.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2946 PF11162.3 EAU92232.1 - 5.2 7.2 10.3 9.2 6.4 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) F-box PF00646.28 EAU92233.2 - 1.7e-05 24.2 0.9 3.6e-05 23.2 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92233.2 - 0.00012 21.7 0.2 0.00025 20.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF3328 PF11807.3 EAU92235.2 - 7.4e-23 81.3 0.5 1.1e-22 80.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) F-box-like PF12937.2 EAU92236.2 - 1.9e-07 30.6 2.6 3.9e-07 29.7 1.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92236.2 - 1.4e-05 24.5 1.6 2.9e-05 23.5 1.1 1.5 1 0 0 1 1 1 1 F-box domain DUF1949 PF09186.6 EAU92237.2 - 0.02 14.4 1.0 0.19 11.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) DUF666 PF05006.7 EAU92237.2 - 0.064 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF666) Rota_NS6 PF04866.7 EAU92239.1 - 0.054 13.5 0.5 5.6 7.0 0.0 2.8 1 1 2 3 3 3 0 Rotavirus non-structural protein 6 FliJ PF02050.11 EAU92239.1 - 1.2 9.2 7.7 4.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2450 PF10475.4 EAU92241.2 - 0.015 14.2 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 EAU92241.2 - 0.023 14.2 1.0 0.045 13.3 0.7 1.4 1 0 0 1 1 1 0 IncA protein TPR_3 PF07720.7 EAU92244.2 - 1.5 8.7 3.2 13 5.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CK2S PF15011.1 EAU92251.1 - 0.061 13.1 0.8 3.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate HLH PF00010.21 EAU92254.2 - 3e-10 39.6 5.1 1.4e-09 37.4 1.5 2.5 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1192 PF06698.6 EAU92254.2 - 0.0044 16.8 0.5 0.0044 16.8 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF724 PF05266.9 EAU92254.2 - 0.039 13.5 0.6 0.059 12.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF342 PF03961.8 EAU92254.2 - 0.04 12.3 2.0 0.054 11.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EAU92254.2 - 0.055 12.9 0.6 0.055 12.9 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator IFP_35_N PF07334.8 EAU92254.2 - 0.11 12.5 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PV-1 PF06637.6 EAU92254.2 - 0.12 10.8 2.3 0.18 10.3 1.6 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) IncA PF04156.9 EAU92254.2 - 0.88 9.1 3.8 1.4 8.4 2.6 1.3 1 0 0 1 1 1 0 IncA protein DUF2919 PF11143.3 EAU92255.2 - 0.017 14.9 3.2 0.058 13.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF4234 PF14018.1 EAU92255.2 - 0.69 9.6 4.1 0.23 11.2 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) HLH PF00010.21 EAU92256.1 - 1.3e-10 40.7 1.4 1.3e-10 40.7 1.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain HlyD PF00529.15 EAU92256.1 - 0.55 9.4 5.9 0.78 8.9 4.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF4433 PF14487.1 EAU92257.2 - 0.1 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4433) TBCA PF02970.11 EAU92258.2 - 2.7e-22 78.6 2.8 3.3e-22 78.3 2.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A MotCF PF09158.5 EAU92258.2 - 0.06 13.0 0.3 0.079 12.6 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal DUF1875 PF08961.5 EAU92258.2 - 0.27 10.5 3.0 0.29 10.4 1.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) Het-C PF07217.6 EAU92260.1 - 8.8e-199 661.6 0.0 8.4e-198 658.3 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C LTV PF04180.9 EAU92261.1 - 5.6e-65 220.4 27.8 1.8e-61 208.9 12.1 3.2 2 1 0 2 2 2 2 Low temperature viability protein Bromodomain PF00439.20 EAU92262.2 - 1.5e-54 181.8 0.0 4.8e-18 64.8 0.0 3.7 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 EAU92262.2 - 8.3e-08 31.7 0.0 1.9e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M1 DUF1777 PF08648.7 EAU92262.2 - 0.00022 21.0 20.0 0.0006 19.5 13.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 EAU92262.2 - 0.43 11.1 30.4 1.3 9.6 21.1 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MRP-L28 PF09812.4 EAU92263.1 - 2.1e-10 40.6 5.2 1e-09 38.4 1.7 2.3 1 1 1 2 2 2 1 Mitochondrial ribosomal protein L28 PhoU PF01895.14 EAU92263.1 - 0.26 11.7 2.0 0.47 10.9 1.3 1.5 1 1 0 1 1 1 0 PhoU domain PCI PF01399.22 EAU92264.2 - 2.7e-20 72.6 0.3 6.7e-20 71.3 0.1 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EAU92264.2 - 1.4e-10 41.0 0.1 3.1e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Rsm22 PF09243.5 EAU92266.1 - 1.4e-42 145.6 0.0 7.5e-28 97.3 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.24 EAU92267.2 - 4.1e-28 98.2 0.0 5.5e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EAU92267.2 - 4e-11 42.8 0.2 7.3e-11 42.0 0.2 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein WD40 PF00400.27 EAU92269.2 - 1.8e-55 182.9 23.5 2.6e-09 36.6 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EAU92269.2 - 0.00094 18.9 0.0 0.33 10.6 0.0 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Myosin_tail_1 PF01576.14 EAU92270.1 - 3e-12 45.1 77.8 3e-12 45.1 53.9 2.3 1 1 1 2 2 2 1 Myosin tail IncA PF04156.9 EAU92270.1 - 1.7e-05 24.5 147.6 0.011 15.3 10.1 6.8 1 1 4 6 6 6 5 IncA protein Reo_sigmaC PF04582.7 EAU92270.1 - 2e-05 23.9 49.0 0.0031 16.7 5.4 5.9 1 1 3 5 5 5 3 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EAU92270.1 - 9.8e-05 21.5 7.8 9.8e-05 21.5 5.4 6.1 1 1 3 4 4 4 2 Tropomyosin ERM PF00769.14 EAU92270.1 - 0.00026 20.6 21.3 0.00026 20.6 14.7 6.6 2 1 4 6 6 5 2 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 EAU92270.1 - 0.00056 19.7 9.9 0.00056 19.7 6.9 7.9 2 1 3 6 6 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EAU92270.1 - 0.0017 18.2 18.8 0.0017 18.2 13.0 7.0 1 1 5 7 7 7 2 Tropomyosin like Fib_alpha PF08702.5 EAU92270.1 - 0.0021 18.2 7.9 0.0021 18.2 5.5 6.8 1 1 7 8 8 7 3 Fibrinogen alpha/beta chain family CALCOCO1 PF07888.6 EAU92270.1 - 0.0025 16.1 22.6 0.0025 16.1 15.7 4.2 1 1 3 4 4 4 2 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_13 PF13166.1 EAU92270.1 - 0.022 13.2 90.5 0.037 12.5 17.5 3.5 1 1 2 3 3 3 0 AAA domain Spc7 PF08317.6 EAU92270.1 - 0.46 9.0 109.6 0.038 12.6 10.1 5.9 1 1 3 5 5 5 0 Spc7 kinetochore protein AAA_27 PF13514.1 EAU92270.1 - 0.63 7.6 118.1 1.2 6.7 27.5 3.5 1 1 0 2 2 2 0 AAA domain Filament PF00038.16 EAU92270.1 - 0.73 9.2 114.5 1.9 7.8 4.9 5.8 2 1 4 6 6 6 0 Intermediate filament protein DUF869 PF05911.6 EAU92270.1 - 3 5.9 99.0 0.012 13.9 24.8 3.8 1 1 1 3 3 3 0 Plant protein of unknown function (DUF869) polyprenyl_synt PF00348.12 EAU92273.2 - 1.8e-20 72.8 0.0 2.8e-17 62.4 0.0 2.3 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EAU92273.2 - 0.082 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RRM_1 PF00076.17 EAU92275.2 - 1.4e-17 63.0 0.0 4.3e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU92275.2 - 4.4e-11 42.4 0.0 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU92275.2 - 1.3e-07 31.4 0.0 1.6e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU92275.2 - 0.0026 17.5 0.1 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Ras PF00071.17 EAU92276.2 - 2.4e-60 202.5 0.1 2.8e-60 202.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU92276.2 - 6.8e-20 71.7 0.0 9.9e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU92276.2 - 1.1e-14 54.0 0.1 1.3e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU92276.2 - 9e-08 31.7 0.0 1.7e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAU92276.2 - 2.6e-06 26.7 0.0 3.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU92276.2 - 8e-06 25.7 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EAU92276.2 - 0.035 14.2 0.0 0.41 10.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EAU92276.2 - 0.035 14.1 0.4 0.087 12.8 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EAU92276.2 - 0.04 13.1 0.3 0.14 11.3 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 DUF385 PF04075.9 EAU92276.2 - 0.056 13.4 0.1 0.095 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF385) G-alpha PF00503.15 EAU92276.2 - 0.089 11.4 0.4 6.1 5.4 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.13 EAU92276.2 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin RasGEF PF00617.14 EAU92277.2 - 8.7e-40 136.4 0.1 1.3e-39 135.9 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EAU92277.2 - 7e-18 64.6 0.0 1.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EAU92277.2 - 1.7e-11 43.3 0.1 3.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAU92277.2 - 5.1e-11 41.9 0.0 1.3e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EAU92277.2 - 5.2e-08 32.3 0.0 1.2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Ist1 PF03398.9 EAU92278.2 - 2.1e-55 186.6 0.8 3e-55 186.1 0.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Indigoidine_A PF04227.7 EAU92278.2 - 0.065 12.4 0.2 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 Indigoidine synthase A like protein Methyltransf_23 PF13489.1 EAU92279.1 - 7.1e-12 45.3 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU92279.1 - 2.1e-08 34.5 0.1 9.3e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU92279.1 - 9.4e-07 29.2 0.0 4.9e-06 26.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU92279.1 - 1.8e-06 28.4 0.3 6.6e-05 23.4 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU92279.1 - 2.1e-06 27.4 0.0 0.027 14.0 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.12 EAU92279.1 - 0.0036 16.3 0.0 0.039 12.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EAU92279.1 - 0.013 15.8 0.2 0.13 12.6 0.1 2.6 2 1 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 EAU92279.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EAU92279.1 - 0.034 14.1 0.1 0.3 11.1 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EAU92279.1 - 0.05 12.7 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.1 EAU92280.2 - 1.2e-12 47.7 0.0 2.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU92280.2 - 2e-11 43.7 0.0 3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU92280.2 - 4.8e-10 39.8 0.0 8.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU92280.2 - 6.9e-09 36.0 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU92280.2 - 1.1e-07 32.4 0.0 2.5e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAU92280.2 - 2.8e-07 29.9 0.0 3.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EAU92280.2 - 1.7e-06 27.2 0.0 4.9e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EAU92280.2 - 0.00028 20.9 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EAU92280.2 - 0.0012 19.2 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EAU92280.2 - 0.002 17.3 0.0 0.0074 15.4 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_29 PF03141.11 EAU92280.2 - 0.0084 14.4 0.0 0.55 8.4 0.0 2.1 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 EAU92280.2 - 0.0086 15.4 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EAU92280.2 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TFIIA PF03153.8 EAU92284.2 - 5.4 6.8 6.6 9.2 6.0 4.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 EAU92284.2 - 6.9 6.0 11.3 14 5.0 7.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 EAU92285.2 - 1e-26 91.7 18.9 1.1e-07 31.4 1.5 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EAU92285.2 - 0.022 12.9 0.0 0.27 9.3 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Sushi PF00084.15 EAU92285.2 - 0.12 12.7 0.4 10 6.5 0.1 2.6 2 0 0 2 2 2 0 Sushi domain (SCR repeat) WD40 PF00400.27 EAU92286.2 - 1e-39 132.9 8.6 9.9e-10 37.9 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Bax1-I PF01027.15 EAU92287.2 - 2e-35 122.3 8.8 2e-35 122.3 6.1 1.6 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Sec1 PF00995.18 EAU92288.1 - 2.3e-141 472.2 0.0 2.6e-141 472.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF221 PF02714.10 EAU92289.2 - 6.1e-18 64.7 18.2 9e-18 64.2 12.6 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EAU92289.2 - 1.6e-05 24.6 0.0 3.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EAU92289.2 - 0.0061 17.0 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4512 PF14975.1 EAU92290.1 - 0.044 14.6 0.0 0.052 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) PhzC-PhzF PF02567.11 EAU92291.1 - 1.2e-27 96.8 0.0 1.9e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Nrap PF03813.9 EAU92291.1 - 0.25 8.8 0.0 0.32 8.4 0.0 1.1 1 0 0 1 1 1 0 Nrap protein DUF4246 PF14033.1 EAU92292.2 - 8.1e-96 321.6 0.0 3e-94 316.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) Rotamase PF00639.16 EAU92294.1 - 2.8e-23 82.4 0.0 3.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EAU92294.1 - 4.8e-20 71.9 0.0 6.4e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EAU92294.1 - 4.1e-07 29.7 1.2 4.3e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EAU92294.1 - 0.00014 22.4 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF2414 PF10309.4 EAU92296.1 - 3.6e-07 29.7 0.0 6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EAU92296.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain RRM_6 PF14259.1 EAU92296.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.22 EAU92297.1 - 3.3e-63 212.5 0.2 4.8e-63 212.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EAU92297.1 - 5.7e-38 129.1 0.0 2.2e-37 127.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EAU92297.1 - 3.1e-22 78.2 0.0 6.4e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EAU92297.1 - 1.4e-13 50.4 0.0 4.7e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EAU92297.1 - 1.4e-12 47.5 0.0 8.3e-12 45.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAU92297.1 - 9.4e-06 25.5 0.1 1.9e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EAU92297.1 - 0.017 14.6 0.6 0.075 12.5 0.2 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FAD_binding_3 PF01494.14 EAU92298.1 - 1.7e-22 79.9 0.2 1.2e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EAU92298.1 - 7e-05 22.7 1.2 0.00018 21.4 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU92298.1 - 7.4e-05 21.8 3.3 0.00018 20.5 0.9 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EAU92298.1 - 0.00016 20.4 0.1 0.012 14.3 0.1 2.7 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EAU92298.1 - 0.00029 19.7 0.6 0.00056 18.8 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EAU92298.1 - 0.0003 21.1 1.2 0.00084 19.6 0.8 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EAU92298.1 - 0.0008 19.3 1.1 0.0016 18.3 0.7 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EAU92298.1 - 0.0023 17.0 1.0 0.0035 16.4 0.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EAU92298.1 - 0.0065 15.3 3.6 0.0095 14.8 2.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EAU92298.1 - 0.007 14.8 2.0 0.0099 14.3 1.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EAU92298.1 - 0.025 13.5 0.5 0.41 9.5 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EAU92298.1 - 0.041 12.9 0.4 0.041 12.9 0.3 1.5 2 0 0 2 2 2 0 Thi4 family SE PF08491.5 EAU92298.1 - 0.096 11.4 0.1 0.26 10.0 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 EAU92298.1 - 0.1 12.3 0.1 4 7.2 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EAU92298.1 - 0.23 11.0 0.8 0.49 10.0 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_3 PF13302.1 EAU92299.1 - 4.1e-21 75.6 0.0 6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU92299.1 - 1.5e-08 34.5 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU92299.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EAU92299.1 - 0.039 13.9 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAU92299.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 EAU92300.1 - 6.2e-22 78.2 0.0 8.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU92300.1 - 3.1e-05 23.8 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EAU92300.1 - 0.0054 16.8 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EAU92300.1 - 0.1 12.4 0.0 2.4 7.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SH3_1 PF00018.23 EAU92301.2 - 2.7e-11 42.6 0.1 4.5e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EAU92301.2 - 4.1e-09 35.7 0.0 8.1e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EAU92301.2 - 2e-08 33.6 0.0 3.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EAU92301.2 - 0.072 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain zf-C3HC4_2 PF13923.1 EAU92302.1 - 3.6e-10 39.6 10.6 6.3e-10 38.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EAU92302.1 - 1.4e-09 37.4 7.5 2.7e-09 36.5 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU92302.1 - 2.7e-08 33.5 10.0 4.7e-08 32.7 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EAU92302.1 - 4.9e-07 29.5 9.9 8.6e-07 28.7 6.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EAU92302.1 - 9.8e-07 28.3 6.0 1.7e-06 27.5 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU92302.1 - 2.9e-06 26.9 7.2 5.1e-06 26.1 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAU92302.1 - 0.00024 20.7 6.2 0.00087 18.9 4.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EAU92302.1 - 0.005 16.6 3.1 0.0093 15.7 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EAU92302.1 - 0.0068 15.9 5.4 0.019 14.4 3.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EAU92302.1 - 0.0072 16.4 3.9 0.017 15.2 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 EAU92302.1 - 0.24 10.9 9.1 0.46 10.0 6.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EAU92302.1 - 3.4 7.5 7.6 1.2 8.9 1.3 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DUF605 PF04652.11 EAU92302.1 - 5.7 6.2 12.0 1.2 8.4 1.4 2.4 2 0 0 2 2 2 0 Vta1 like NpwBP PF12622.2 EAU92303.2 - 1.4e-18 67.0 8.3 1.4e-18 67.0 5.8 7.9 3 1 2 5 5 5 1 mRNA biogenesis factor Wbp11 PF09429.5 EAU92303.2 - 4.8e-16 58.5 15.4 8.4e-16 57.7 10.6 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 V-SNARE PF05008.10 EAU92303.2 - 1.6 8.9 6.5 3.9 7.7 4.5 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus APG6 PF04111.7 EAU92303.2 - 3.7 6.5 9.3 4.9 6.0 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Cation_efflux PF01545.16 EAU92304.2 - 3.6e-19 68.9 2.8 2.6e-10 39.8 0.0 2.8 2 1 0 2 2 2 2 Cation efflux family Herpes_UL45 PF05473.7 EAU92306.2 - 0.007 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 UL45 protein MFS_1 PF07690.11 EAU92307.1 - 8.4e-21 74.0 16.5 1.4e-20 73.3 11.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3493 PF11998.3 EAU92307.1 - 0.14 12.0 2.8 17 5.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) PrgI PF12666.2 EAU92307.1 - 0.4 10.8 5.8 13 5.9 0.0 3.8 3 0 0 3 3 3 0 PrgI family protein Cpn60_TCP1 PF00118.19 EAU92308.1 - 2.2e-143 478.4 0.0 2.5e-143 478.2 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.18 EAU92309.2 - 3e-67 226.5 0.0 4e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU92309.2 - 2.7e-12 46.3 0.0 5.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EAU92309.2 - 3.4e-09 36.5 0.0 1.3e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 HIRAN domain DEAD PF00270.24 EAU92309.2 - 3.2e-08 33.2 0.0 8.5e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU92309.2 - 2e-06 27.7 0.0 7.5e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EAU92309.2 - 2.6e-06 27.0 12.6 4.6e-06 26.1 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU92309.2 - 2.5e-05 24.0 12.7 2.9e-05 23.7 7.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EAU92309.2 - 3e-05 23.5 8.1 5.1e-05 22.8 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU92309.2 - 4.7e-05 23.3 13.1 0.0001 22.2 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU92309.2 - 0.00027 20.5 11.0 0.00046 19.8 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EAU92309.2 - 0.02 14.7 14.3 0.037 13.9 9.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EAU92309.2 - 0.079 12.6 7.1 0.5 10.1 5.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-Nse PF11789.3 EAU92309.2 - 0.097 12.2 7.0 0.21 11.1 4.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 EAU92309.2 - 0.27 10.7 7.1 0.49 9.9 4.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Patched PF02460.13 EAU92309.2 - 0.52 8.1 0.1 0.78 7.5 0.1 1.1 1 0 0 1 1 1 0 Patched family RNase_H PF00075.19 EAU92310.2 - 3.4e-25 88.9 0.0 6.3e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EAU92310.2 - 4.8e-19 68.1 1.0 8.1e-19 67.3 0.7 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin F-box-like PF12937.2 EAU92311.1 - 5e-05 22.9 0.0 0.00018 21.1 0.0 1.9 1 1 0 1 1 1 1 F-box-like DUF837 PF05769.6 EAU92312.2 - 1.5e-09 37.6 13.7 8.6e-07 28.6 4.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF837) NYD-SP28_assoc PF14775.1 EAU92312.2 - 0.0086 15.7 15.8 0.16 11.6 1.8 3.3 3 0 0 3 3 3 2 Sperm tail C-terminal domain DUF3920 PF13058.1 EAU92312.2 - 0.093 12.5 0.5 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) Herpes_BLRF2 PF05812.7 EAU92312.2 - 0.71 9.6 8.0 2.8 7.7 0.6 2.5 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Rnk_N PF14760.1 EAU92312.2 - 1.8 8.6 0.0 1.8 8.6 0.0 3.8 5 0 0 5 5 5 0 Rnk N-terminus DUF972 PF06156.8 EAU92312.2 - 3.8 7.9 19.0 1 9.7 2.6 3.9 3 1 2 5 5 5 0 Protein of unknown function (DUF972) HALZ PF02183.13 EAU92312.2 - 7.3 6.4 10.7 7.9 6.2 0.6 3.9 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF874 PF05917.6 EAU92315.2 - 0.68 8.7 5.0 1.2 7.9 3.5 1.3 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) BSP PF04450.7 EAU92318.2 - 5e-64 215.5 0.0 6e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EAU92318.2 - 6.8e-07 29.3 0.1 3.3e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EAU92318.2 - 0.013 15.1 0.4 0.03 13.9 0.1 1.7 2 0 0 2 2 2 0 SprT-like family HLH PF00010.21 EAU92319.1 - 3.7e-06 26.5 0.0 7.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF605 PF04652.11 EAU92319.1 - 3.1 7.1 19.5 3.9 6.7 13.5 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EAU92319.1 - 3.5 5.7 16.6 4.5 5.3 11.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 EAU92320.2 - 1.1 9.0 8.6 1.2 8.9 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) F-box-like PF12937.2 EAU92321.2 - 0.021 14.5 0.1 0.06 13.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like HSV_VP16_C PF12149.3 EAU92321.2 - 0.024 14.3 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Herpes simplex virus virion protein 16 C terminal UCH PF00443.24 EAU92322.2 - 2.3e-50 171.2 0.0 3.3e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EAU92322.2 - 1.8e-22 80.1 0.0 3.8e-22 79.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MOSC_N PF03476.11 EAU92323.1 - 2.5e-18 65.9 0.0 4.9e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EAU92323.1 - 9.6e-15 54.2 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Methyltransf_16 PF10294.4 EAU92324.2 - 1e-16 60.8 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAU92324.2 - 0.025 15.1 0.0 0.73 10.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Bot1p PF12298.3 EAU92325.1 - 4.8e-46 156.8 1.0 8.1e-46 156.0 0.7 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 EAU92325.1 - 0.036 14.0 0.1 0.036 14.0 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 F5_F8_type_C PF00754.20 EAU92326.1 - 4.6e-06 26.5 0.3 7.4e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 F5/8 type C domain APC10 PF03256.11 EAU92326.1 - 0.0078 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) DUF1501 PF07394.7 EAU92326.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Y_phosphatase PF00102.22 EAU92327.1 - 2.1e-37 128.7 0.0 7.6e-22 77.7 0.0 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EAU92327.1 - 0.0042 17.1 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate ADH_zinc_N PF00107.21 EAU92328.2 - 6.4e-29 100.1 0.1 1e-28 99.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EAU92328.2 - 2.1e-12 48.0 0.0 6.7e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EAU92328.2 - 2e-06 27.5 0.0 7.1e-06 25.7 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 EAU92328.2 - 0.01 15.5 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 SIS domain UCH PF00443.24 EAU92329.1 - 1.6e-42 145.4 0.0 4.7e-42 143.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EAU92329.1 - 8.3e-26 89.1 1.0 5.1e-20 70.6 0.1 2.5 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EAU92329.1 - 2e-13 50.4 0.4 2.7e-07 30.3 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EAU92329.1 - 0.00017 21.2 0.2 0.00048 19.8 0.1 1.7 1 0 0 1 1 1 1 PUB domain Thiol-ester_cl PF10569.4 EAU92331.2 - 0.1 11.8 1.8 0.11 11.6 0.2 1.8 2 0 0 2 2 2 0 Alpha-macro-globulin thiol-ester bond-forming region F-box-like PF12937.2 EAU92332.1 - 0.0011 18.6 0.0 0.0038 16.9 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92332.1 - 0.0044 16.6 1.6 0.12 12.0 1.1 2.8 1 1 0 1 1 1 1 F-box domain HSP70 PF00012.15 EAU92333.2 - 0.016 13.1 0.0 0.023 12.6 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein Peptidase_M22 PF00814.20 EAU92333.2 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family efThoc1 PF11957.3 EAU92334.2 - 6.7e-98 328.3 3.6 9.1e-94 314.6 1.3 2.2 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Epimerase PF01370.16 EAU92334.2 - 1.2e-33 116.4 0.0 2.6e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EAU92334.2 - 3.8e-24 84.3 0.0 9.3e-24 83.1 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit adh_short PF00106.20 EAU92334.2 - 7.2e-05 22.7 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EAU92334.2 - 7.8e-05 21.7 0.0 0.00015 20.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EAU92334.2 - 9.8e-05 22.0 0.0 0.00044 19.9 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EAU92334.2 - 0.0017 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EAU92334.2 - 0.0042 16.0 0.0 0.0081 15.0 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Dus PF01207.12 EAU92337.1 - 2.6e-52 177.5 0.0 4.9e-52 176.6 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) CCDC32 PF14989.1 EAU92337.1 - 0.099 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing 32 TPR_11 PF13414.1 EAU92339.1 - 1e-21 76.3 17.4 1.6e-17 62.8 3.8 4.1 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 EAU92339.1 - 9.5e-13 47.1 17.2 0.00036 19.9 0.2 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU92339.1 - 4.1e-11 41.9 22.1 0.00033 20.3 0.2 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EAU92339.1 - 2.3e-07 30.4 11.1 0.00011 22.1 0.3 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU92339.1 - 0.0078 16.7 12.7 0.024 15.2 2.8 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU92339.1 - 0.062 13.9 15.7 0.41 11.3 0.8 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EAU92339.1 - 0.1 12.9 10.9 0.18 12.1 4.4 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DivIVA PF05103.8 EAU92339.1 - 0.37 10.8 5.0 0.075 13.0 0.4 2.0 2 0 0 2 2 2 0 DivIVA protein NSF PF02071.15 EAU92339.1 - 3.8 8.4 5.6 3.3 8.6 0.4 3.6 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.1 EAU92339.1 - 5 7.1 12.1 15 5.6 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU92339.1 - 7.5 6.5 18.1 21 5.1 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAU92340.1 - 1.1e-19 69.7 2.4 1.7e-15 56.4 1.0 3.0 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EAU92340.1 - 7.7e-13 47.3 3.2 0.00022 20.9 0.1 4.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EAU92340.1 - 3.5e-12 45.3 3.1 2.4e-05 23.7 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU92340.1 - 1.1e-08 35.4 0.1 0.01 16.5 0.0 4.0 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU92340.1 - 8.8e-06 25.9 3.6 0.022 15.3 0.0 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU92340.1 - 0.00012 21.5 0.0 5.4 7.0 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU92340.1 - 0.0028 17.5 2.5 0.41 10.6 0.3 3.3 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU92340.1 - 0.0034 17.6 0.1 0.022 15.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EAU92340.1 - 0.018 15.2 0.0 1.4 9.2 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAU92340.1 - 0.021 14.6 0.0 6.6 6.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EAU92340.1 - 0.042 12.6 0.1 0.067 11.9 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EAU92340.1 - 0.059 13.8 0.0 15 6.3 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat NETI PF14044.1 EAU92340.1 - 0.078 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 NETI protein TPR_11 PF13414.1 EAU92341.2 - 4.4e-25 87.1 3.0 2.4e-20 71.9 1.9 3.4 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EAU92341.2 - 7e-21 72.9 9.1 3.1e-07 29.7 0.5 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU92341.2 - 2.6e-17 61.2 13.7 2.7e-06 26.8 0.2 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EAU92341.2 - 5.5e-11 42.8 8.0 5.5e-09 36.4 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU92341.2 - 5.2e-08 32.8 1.0 0.0052 17.3 0.4 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU92341.2 - 1.9e-07 30.9 6.9 0.0061 16.4 0.7 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EAU92341.2 - 1.3e-06 27.7 2.9 0.019 14.7 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU92341.2 - 3.9e-06 26.6 6.4 0.047 13.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EAU92341.2 - 8e-05 22.8 1.9 0.00022 21.4 1.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU92341.2 - 0.00084 18.9 3.1 0.083 12.7 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EAU92341.2 - 0.006 16.8 0.8 0.22 11.8 0.1 2.8 2 1 0 3 3 2 1 Bacterial transcriptional activator domain Apc3 PF12895.2 EAU92341.2 - 0.023 14.8 1.2 0.082 13.0 0.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EAU92341.2 - 0.025 15.0 1.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EAU92341.2 - 0.17 11.8 4.6 0.38 10.6 0.7 3.2 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Prefoldin_2 PF01920.15 EAU92342.1 - 8.5e-17 60.8 6.8 1e-16 60.5 4.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 EAU92342.1 - 0.0022 17.8 2.6 0.0022 17.8 1.8 1.9 2 0 0 2 2 2 1 Tropomyosin like Phlebovirus_NSM PF07246.6 EAU92342.1 - 0.031 13.4 2.3 0.11 11.5 0.2 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M CorA PF01544.13 EAU92342.1 - 0.037 13.0 2.5 2.8 6.8 0.2 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FliD_C PF07195.7 EAU92342.1 - 0.067 12.4 3.4 0.31 10.3 2.3 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Seryl_tRNA_N PF02403.17 EAU92342.1 - 0.22 11.5 7.8 0.98 9.4 5.4 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 EAU92342.1 - 0.68 7.7 3.6 0.77 7.5 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF148 PF02520.12 EAU92342.1 - 4.5 7.1 8.2 1.4 8.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 XhlA PF10779.4 EAU92342.1 - 6.7 6.7 7.2 0.7 9.8 0.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA ABC2_membrane PF01061.19 EAU92343.2 - 8.1e-76 253.8 47.6 8.9e-41 139.3 13.9 2.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EAU92343.2 - 2.2e-33 115.4 0.0 3.4e-15 56.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EAU92343.2 - 7e-20 70.6 0.9 6.7e-16 57.8 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EAU92343.2 - 7.5e-09 35.5 1.5 1.1e-08 35.0 0.4 1.8 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EAU92343.2 - 1.5e-05 24.5 0.2 0.043 13.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EAU92343.2 - 1.8e-05 24.9 0.2 0.39 10.8 0.1 3.1 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 EAU92343.2 - 4.8e-05 22.8 0.0 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EAU92343.2 - 4.8e-05 23.2 0.1 0.11 12.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EAU92343.2 - 0.00037 21.3 0.0 0.32 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EAU92343.2 - 0.00047 19.6 0.1 0.042 13.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EAU92343.2 - 0.0012 18.8 0.3 0.31 11.0 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAU92343.2 - 0.0023 18.2 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU92343.2 - 0.0054 16.4 0.9 0.7 9.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 EAU92343.2 - 0.011 15.9 0.1 2.7 8.1 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EAU92343.2 - 0.017 14.7 0.2 5.5 6.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EAU92343.2 - 0.028 13.6 0.0 0.49 9.5 0.0 2.8 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EAU92343.2 - 0.031 13.4 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EAU92343.2 - 0.04 13.3 1.2 6.2 6.2 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 EAU92343.2 - 0.051 13.4 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EAU92343.2 - 0.055 13.4 0.0 17 5.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAU92343.2 - 0.074 13.0 4.9 0.53 10.2 0.2 3.3 3 1 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 EAU92343.2 - 0.14 12.4 0.7 4.5 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Glyco_hydro_cc PF11790.3 EAU92344.1 - 3.4e-65 219.8 0.2 4.3e-65 219.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF-hand_6 PF13405.1 EAU92345.1 - 7.1e-10 37.9 0.2 1.6e-05 24.3 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EAU92345.1 - 1.7e-07 30.2 1.2 0.00049 19.3 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EAU92345.1 - 5e-07 29.7 0.6 3.4e-06 27.1 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EAU92345.1 - 0.00016 20.6 0.2 0.074 12.3 0.0 2.7 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 EAU92345.1 - 0.02 14.9 3.7 0.85 9.6 0.1 2.7 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Dopey_N PF04118.9 EAU92346.2 - 9.1e-109 362.9 1.3 3.3e-108 361.1 0.0 2.6 2 0 0 2 2 2 1 Dopey, N-terminal ATP-synt_E PF05680.7 EAU92348.2 - 3e-21 75.1 0.6 3.3e-21 75.0 0.4 1.1 1 0 0 1 1 1 1 ATP synthase E chain Acylphosphatase PF00708.13 EAU92348.2 - 0.037 14.1 0.0 0.041 13.9 0.0 1.3 1 1 0 1 1 1 0 Acylphosphatase DUF3810 PF12725.2 EAU92348.2 - 0.062 12.1 0.2 0.066 12.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) AIF-MLS PF14962.1 EAU92348.2 - 0.084 12.5 0.1 0.089 12.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence WD40 PF00400.27 EAU92349.2 - 3e-37 125.1 7.9 3.9e-09 36.0 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EAU92349.2 - 5.1e-26 90.3 0.2 1.1e-25 89.2 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex RAMP4 PF06624.7 EAU92350.2 - 2.1e-09 36.8 0.0 2.8e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1104 PF06518.6 EAU92350.2 - 0.083 13.0 0.3 0.093 12.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) Na_K-ATPase PF00287.13 EAU92350.2 - 0.16 10.7 0.0 0.16 10.6 0.0 1.0 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain DUF2431 PF10354.4 EAU92351.1 - 2.4e-38 131.7 0.0 1.1e-37 129.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Fip1 PF05182.8 EAU92353.1 - 8.7e-20 69.7 1.6 1.5e-19 68.9 1.1 1.4 1 0 0 1 1 1 1 Fip1 motif Nop14 PF04147.7 EAU92353.1 - 0.28 9.0 3.6 0.38 8.6 2.5 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EAU92353.1 - 8 6.1 5.6 3.6 7.2 2.2 1.5 2 0 0 2 2 2 0 FAM176 family ING PF12998.2 EAU92354.1 - 4.9e-13 49.2 0.2 7.9e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EAU92354.1 - 2.6e-09 36.6 5.4 4.2e-09 35.9 3.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EAU92354.1 - 0.45 9.8 3.7 0.79 9.0 2.6 1.4 1 0 0 1 1 1 0 PHD-finger Serglycin PF04360.7 EAU92354.1 - 7.2 6.3 10.2 1.2 8.8 2.6 2.2 1 1 1 2 2 2 0 Serglycin Calcipressin PF04847.7 EAU92355.1 - 0.035 13.6 0.1 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 Calcipressin Nucleoporin_FG PF13634.1 EAU92355.1 - 0.11 12.7 9.3 0.17 12.1 6.5 1.3 1 1 0 1 1 1 0 Nucleoporin FG repeat region NAD_binding_1 PF00175.16 EAU92357.2 - 3.2e-26 92.0 0.0 5.7e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EAU92357.2 - 2.1e-17 63.0 0.0 4.6e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EAU92357.2 - 8.1e-08 32.3 0.1 4.8e-05 23.2 0.0 2.5 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EAU92357.2 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Pkinase PF00069.20 EAU92358.2 - 2.4e-71 239.9 0.0 2.9e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92358.2 - 3.4e-31 108.2 0.0 4.4e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EAU92358.2 - 0.00029 19.9 0.0 0.0008 18.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EAU92358.2 - 0.00045 20.0 0.0 0.00078 19.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU92358.2 - 0.0023 16.9 0.0 0.023 13.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EAU92358.2 - 0.0092 15.3 0.1 0.049 12.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family DUF1221 PF06760.6 EAU92359.2 - 0.076 12.2 1.0 0.11 11.7 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1221) DNA_methylase PF00145.12 EAU92360.2 - 6.7e-36 124.0 0.0 2.4e-34 118.9 0.0 2.9 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EAU92360.2 - 4.1e-14 52.3 0.1 9.6e-10 38.2 0.0 2.6 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EAU92360.2 - 6.2e-09 35.7 0.0 1.5e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Methyltransf_26 PF13659.1 EAU92360.2 - 0.039 14.0 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DnaJ PF00226.26 EAU92361.1 - 1.9e-16 59.5 0.5 3.3e-16 58.7 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EAU92361.1 - 6.4e-12 44.7 0.2 1.1e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger Dor1 PF04124.7 EAU92363.1 - 5.7e-47 159.8 1.0 4.2e-32 110.9 0.4 2.2 2 0 0 2 2 2 2 Dor1-like family Sec5 PF15469.1 EAU92363.1 - 7.7e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EAU92363.1 - 0.011 15.6 0.1 0.031 14.1 0.1 1.8 1 0 0 1 1 1 0 Vps51/Vps67 F-box-like PF12937.2 EAU92365.1 - 1e-05 25.1 0.3 2.3e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EAU92367.2 - 3.4e-07 29.8 0.1 8.9e-07 28.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92367.2 - 2e-06 27.2 0.1 6.6e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EAU92367.2 - 0.01 15.5 0.4 0.09 12.5 0.3 2.8 2 1 0 2 2 2 0 F-box-like domain IBN_N PF03810.14 EAU92368.2 - 3.1e-06 27.0 0.0 0.0046 16.8 0.0 4.5 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EAU92368.2 - 0.00018 21.7 2.5 0.029 14.6 0.0 5.2 4 2 2 6 6 6 2 HEAT repeats ParcG PF10274.4 EAU92368.2 - 0.0051 16.7 0.3 1.7 8.4 0.0 3.3 4 0 0 4 4 4 1 Parkin co-regulated protein RIX1 PF08167.7 EAU92368.2 - 0.0061 16.2 2.2 0.068 12.8 0.1 3.7 4 2 0 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.7 EAU92368.2 - 0.013 15.3 0.1 0.13 12.1 0.0 3.0 3 1 0 3 3 3 0 Exportin 1-like protein HEAT PF02985.17 EAU92368.2 - 0.034 14.2 3.3 0.25 11.5 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat DUF1956 PF09209.6 EAU92368.2 - 0.071 13.0 0.1 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1956) HEAT_EZ PF13513.1 EAU92368.2 - 0.082 13.4 7.0 68 4.1 0.0 6.8 7 0 0 7 7 7 0 HEAT-like repeat Adaptin_N PF01602.15 EAU92368.2 - 0.17 10.1 0.0 1.1 7.4 0.0 2.2 3 0 0 3 3 3 0 Adaptin N terminal region RabGAP-TBC PF00566.13 EAU92369.2 - 8.3e-42 143.0 0.0 1.3e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.2 EAU92371.1 - 1.3e-05 24.7 0.0 3.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 F-box-like Tyrosinase PF00264.15 EAU92372.2 - 4.1e-39 135.0 0.5 5.6e-39 134.5 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Ank_4 PF13637.1 EAU92374.1 - 2.2e-14 53.5 0.0 2.8e-07 30.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EAU92374.1 - 1.4e-13 50.9 0.2 1.1e-06 28.9 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EAU92374.1 - 1e-12 47.1 0.1 9.5e-05 22.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EAU92374.1 - 1.3e-12 47.4 0.5 3.9e-06 26.9 0.2 3.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU92374.1 - 7e-11 41.2 0.1 0.00026 20.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat SBP_bac_3 PF00497.15 EAU92374.1 - 0.1 11.8 0.0 0.84 8.8 0.0 2.1 2 1 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Pkinase PF00069.20 EAU92375.1 - 5e-36 124.1 0.0 5.3e-35 120.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92375.1 - 5.9e-18 64.8 0.0 8.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU92375.1 - 3.3e-06 26.2 0.0 5.1e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU92375.1 - 0.00015 21.6 0.0 0.0048 16.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EAU92375.1 - 0.0036 16.2 0.0 0.0051 15.6 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 EAU92375.1 - 0.0052 16.3 0.0 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EAU92375.1 - 0.0062 15.6 0.0 0.015 14.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Ask1 PF08655.5 EAU92376.1 - 6.7e-21 73.8 0.1 1.4e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 CENP-B_dimeris PF09026.5 EAU92377.1 - 0.024 14.8 3.1 0.024 14.8 2.1 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mus7 PF09462.5 EAU92377.1 - 0.082 11.7 0.2 0.092 11.5 0.1 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family BTK PF00779.14 EAU92377.1 - 0.82 9.3 5.1 0.24 11.0 1.2 1.8 2 0 0 2 2 2 0 BTK motif Voldacs PF03517.8 EAU92377.1 - 0.87 9.4 6.2 0.36 10.6 1.0 2.3 1 1 1 2 2 2 0 Regulator of volume decrease after cellular swelling Cu_amine_oxid PF01179.15 EAU92378.2 - 8.2e-151 502.4 0.0 1e-150 502.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EAU92378.2 - 7.6e-18 64.4 0.0 1.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EAU92378.2 - 1.8e-05 24.7 0.0 5.1e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TauD PF02668.11 EAU92379.2 - 2.8e-28 99.3 0.1 4.5e-28 98.6 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C2H2 PF00096.21 EAU92380.2 - 1.7e-12 46.9 39.5 0.0012 19.0 0.3 7.4 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU92380.2 - 7.3e-11 41.6 38.4 0.0011 19.0 0.1 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU92380.2 - 2.5e-09 36.9 30.6 0.00067 19.7 0.2 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EAU92380.2 - 1.4e-07 31.1 30.3 0.0025 17.6 0.1 7.3 6 1 1 7 7 7 3 C2H2-type zinc finger zf-met PF12874.2 EAU92380.2 - 1.4e-06 28.3 30.1 0.0088 16.2 0.1 6.9 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAU92380.2 - 0.012 15.6 23.6 0.05 13.7 8.3 4.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EAU92380.2 - 0.013 15.1 0.1 0.013 15.1 0.0 6.3 7 0 0 7 7 7 0 zinc-finger of a C2HC-type DUF4187 PF13821.1 EAU92380.2 - 0.2 11.2 11.3 2.6 7.7 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4187) DZR PF12773.2 EAU92380.2 - 0.34 10.7 20.6 6.5e+02 0.2 11.8 4.2 2 1 0 2 2 2 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.10 EAU92380.2 - 1.3 8.6 0.0 1.3 8.6 0.0 4.6 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger C1_4 PF07975.7 EAU92380.2 - 8.6 6.4 34.1 4.1 7.4 0.1 5.3 3 2 3 6 6 6 0 TFIIH C1-like domain zf-CCHC PF00098.18 EAU92381.1 - 3.4e-06 26.6 1.5 3.4e-06 26.6 1.0 1.9 2 0 0 2 2 2 1 Zinc knuckle dCMP_cyt_deam_2 PF08211.6 EAU92381.1 - 0.016 15.1 0.2 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2603 PF10788.4 EAU92385.1 - 0.0044 16.7 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2603) Seryl_tRNA_N PF02403.17 EAU92386.2 - 1.1 9.3 7.1 18 5.4 5.3 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain G10 PF01125.12 EAU92389.2 - 0.038 13.5 0.3 0.054 13.0 0.2 1.4 1 1 0 1 1 1 0 G10 protein zf-C2H2_2 PF12756.2 EAU92389.2 - 0.062 13.4 6.6 1.2 9.2 0.2 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) PTA_PTB PF01515.14 EAU92389.2 - 0.075 12.0 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase zf-C2H2_4 PF13894.1 EAU92389.2 - 6.8 7.2 7.5 3.9 8.0 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EAU92390.1 - 4.8e-12 45.2 38.0 0.011 15.9 0.8 8.2 9 0 0 9 9 9 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU92390.1 - 1.3e-11 44.2 35.3 6.9e-07 29.2 0.2 7.4 7 1 1 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU92390.1 - 2.5e-11 43.3 25.2 4.3e-06 26.7 0.3 6.1 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EAU92390.1 - 2.1e-10 40.3 46.8 0.08 13.3 1.5 7.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EAU92390.1 - 0.013 15.5 26.6 0.16 12.0 1.1 4.7 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EAU92390.1 - 0.56 10.5 0.0 0.56 10.5 0.0 7.1 7 0 0 7 7 7 0 Zinc-finger double domain GRAM PF02893.15 EAU92392.2 - 1.1e-14 53.7 0.0 2.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Homeobox PF00046.24 EAU92393.1 - 2.2e-16 59.2 5.5 4.3e-16 58.2 3.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAU92393.1 - 0.0028 17.3 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain MFS_1 PF07690.11 EAU92394.2 - 4.5e-24 84.8 25.2 4.5e-24 84.8 17.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Enolase_C PF00113.17 EAU92397.1 - 2.7e-145 482.8 0.0 3.6e-145 482.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EAU92397.1 - 4.2e-59 198.1 0.2 6.9e-59 197.5 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EAU92397.1 - 4.4e-05 23.4 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EAU92397.1 - 0.00099 18.1 0.1 0.0022 16.9 0.1 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EAU92397.1 - 0.022 15.2 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain NGP1NT PF08153.7 EAU92398.1 - 6.1e-47 158.8 0.0 1.7e-46 157.3 0.0 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EAU92398.1 - 5.3e-20 71.5 0.0 1.1e-15 57.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU92398.1 - 2e-05 23.9 0.2 0.00013 21.2 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EAU92398.1 - 4.5e-05 22.9 0.3 0.0088 15.4 0.1 3.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EAU92398.1 - 0.00062 18.9 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Nuc_deoxyrib_tr PF05014.10 EAU92398.1 - 0.0051 16.6 1.6 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase Arf PF00025.16 EAU92398.1 - 0.017 14.3 0.0 0.41 9.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Nop14 PF04147.7 EAU92398.1 - 8.1 4.2 33.2 13 3.4 23.0 1.2 1 0 0 1 1 1 0 Nop14-like family Inositol_P PF00459.20 EAU92401.1 - 1.1e-65 221.6 0.0 1.3e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Proteasome PF00227.21 EAU92402.1 - 9.9e-58 194.5 0.0 1.3e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EAU92402.1 - 2e-14 52.5 0.0 3.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribonuc_L-PSP PF01042.16 EAU92403.1 - 4.9e-44 148.9 0.1 5.6e-44 148.7 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP G-alpha PF00503.15 EAU92404.2 - 2.1e-101 339.4 0.0 9.6e-101 337.2 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU92404.2 - 1.1e-12 47.5 0.1 2e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EAU92404.2 - 0.0023 17.4 0.5 0.0074 15.7 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EAU92404.2 - 0.036 13.4 0.1 0.34 10.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EAU92404.2 - 0.047 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EAU92404.2 - 0.049 12.7 0.4 4.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DAP3 PF10236.4 EAU92404.2 - 0.1 11.4 0.3 0.16 10.8 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Herpes_gE PF02480.11 EAU92405.2 - 0.022 13.0 0.0 0.041 12.1 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EAU92405.2 - 0.17 11.5 0.3 0.42 10.2 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain Glyco_hydro_47 PF01532.15 EAU92406.2 - 3.1e-143 477.7 0.0 3.8e-143 477.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Prenylcys_lyase PF07156.9 EAU92408.1 - 0.21 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase Tyrosinase PF00264.15 EAU92409.1 - 2.2e-40 139.1 2.9 3.1e-40 138.6 2.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase BTB_2 PF02214.17 EAU92410.1 - 0.0004 20.5 0.0 0.026 14.7 0.0 3.0 3 0 0 3 3 3 1 BTB/POZ domain Na_trans_assoc PF06512.8 EAU92411.2 - 0.17 11.7 8.6 0.26 11.2 5.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.7 EAU92411.2 - 0.69 7.7 12.5 0.97 7.2 8.6 1.2 1 0 0 1 1 1 0 Nop14-like family Cation_efflux PF01545.16 EAU92411.2 - 0.72 8.8 7.4 2.6 7.0 5.1 1.9 1 1 0 1 1 1 0 Cation efflux family Peptidase_U4 PF03419.8 EAU92411.2 - 2.4 7.1 5.7 0.53 9.3 1.2 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Chitin_synth_2 PF03142.10 EAU92412.2 - 6.8e-278 922.3 0.0 1.1e-277 921.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EAU92412.2 - 3.5e-15 56.2 0.6 9.8e-15 54.7 0.4 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAU92412.2 - 1.2e-11 44.9 0.0 8.1e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EAU92412.2 - 9.8e-07 28.4 0.2 3.4e-05 23.5 0.1 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EAU92412.2 - 0.0002 20.6 0.0 0.0083 15.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EAU92412.2 - 0.0095 15.6 0.0 0.056 13.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Sec61_beta PF03911.11 EAU92412.2 - 0.68 9.7 4.1 1.8 8.4 2.9 1.8 1 0 0 1 1 1 0 Sec61beta family ABC_tran PF00005.22 EAU92413.1 - 1.3e-27 96.7 0.0 3.6e-27 95.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU92413.1 - 9.3e-14 52.0 0.5 6.7e-13 49.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EAU92413.1 - 2.1e-07 30.3 0.0 0.00045 19.3 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EAU92413.1 - 3e-06 26.6 0.0 0.0071 15.5 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAU92413.1 - 0.00037 19.9 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU92413.1 - 0.0018 18.3 1.1 0.0058 16.6 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 EAU92413.1 - 0.0022 18.3 0.0 0.0059 16.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EAU92413.1 - 0.023 14.8 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EAU92413.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain SbcCD_C PF13558.1 EAU92413.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EAU92413.1 - 0.047 12.8 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EAU92413.1 - 0.051 13.2 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 1 0 NACHT domain ATP-synt_ab PF00006.20 EAU92413.1 - 0.092 12.2 0.0 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Caprin-1_C PF12287.3 EAU92413.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term AAA_30 PF13604.1 EAU92413.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EAU92413.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.1 EAU92413.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAU92413.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin zf-C2H2_4 PF13894.1 EAU92414.2 - 2.9e-08 33.4 6.6 0.00038 20.5 2.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU92414.2 - 2.1e-05 24.5 11.4 0.0053 17.0 1.1 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EAU92414.2 - 0.00027 21.0 6.0 0.028 14.5 0.5 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EAU92414.2 - 0.049 13.7 0.4 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 EAU92414.2 - 0.07 13.4 1.0 0.07 13.4 0.7 3.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.2 EAU92414.2 - 0.11 12.7 0.2 14 6.0 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PfkB PF00294.19 EAU92415.1 - 9.3e-67 225.2 1.6 1e-66 225.1 1.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EAU92415.1 - 0.00033 19.9 0.0 0.007 15.5 0.0 2.3 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase COesterase PF00135.23 EAU92417.2 - 9.1e-97 324.9 0.1 1.4e-96 324.3 0.1 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EAU92417.2 - 0.00087 18.9 0.5 0.0087 15.6 0.4 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L28e PF01778.12 EAU92418.1 - 9.8e-31 106.5 0.0 1.2e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DAP PF15228.1 EAU92419.1 - 0.0028 18.3 7.8 0.0041 17.7 5.4 1.3 1 1 0 1 1 1 1 Death-associated protein VirC2 PF07181.6 EAU92419.1 - 0.17 11.2 1.4 0.2 11.0 1.0 1.1 1 0 0 1 1 1 0 VirC2 protein WBS_methylT PF12589.3 EAU92419.1 - 0.35 11.3 6.1 0.43 11.0 4.2 1.1 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome F-box-like PF12937.2 EAU92421.2 - 3.4e-06 26.6 0.3 9.2e-06 25.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92421.2 - 8.1e-05 22.1 0.1 0.00053 19.5 0.1 2.3 2 0 0 2 2 2 1 F-box domain DUF1795 PF08786.6 EAU92421.2 - 0.029 14.2 0.0 0.16 11.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1795) LysM PF01476.15 EAU92422.1 - 9.4e-11 41.4 0.0 1.5e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain Tyrosinase PF00264.15 EAU92423.1 - 7.1e-41 140.7 3.9 9.3e-41 140.4 2.7 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyridox_oxase_2 PF12766.2 EAU92424.1 - 3e-24 85.2 0.0 5e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EAU92424.1 - 0.00077 19.4 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Abhydrolase_6 PF12697.2 EAU92425.2 - 9.5e-27 94.3 0.0 1.6e-26 93.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU92425.2 - 3.1e-14 53.0 0.1 1.7e-12 47.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU92425.2 - 1e-08 35.0 0.0 4.3e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAU92425.2 - 0.00019 21.2 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EAU92426.2 - 9.7e-29 100.8 0.0 2.6e-28 99.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU92426.2 - 1.3e-16 60.8 0.0 1.7e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU92426.2 - 1.1e-10 41.3 0.0 3.9e-10 39.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAU92426.2 - 3e-05 23.7 0.0 6.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 EAU92426.2 - 0.17 11.1 0.0 0.35 10.1 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) PulG PF11773.3 EAU92428.2 - 0.047 13.4 2.0 29 4.4 0.0 3.6 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin WBP-1 PF11669.3 EAU92429.2 - 1 9.4 0.0 1 9.4 0.0 2.6 4 1 0 4 4 4 0 WW domain-binding protein 1 YukC PF10140.4 EAU92429.2 - 1.2 7.5 4.7 0.13 10.8 0.1 1.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC RdRP PF05183.7 EAU92432.2 - 6.9e-130 434.4 0.0 9.5e-130 434.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase LppC PF04348.8 EAU92432.2 - 0.0078 14.8 0.8 0.012 14.2 0.6 1.1 1 0 0 1 1 1 1 LppC putative lipoprotein EF-hand_1 PF00036.27 EAU92433.1 - 9.3e-27 90.2 17.5 8.1e-10 37.2 0.2 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EAU92433.1 - 2.8e-24 85.0 13.9 1.5e-12 47.4 2.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAU92433.1 - 1.6e-23 80.4 13.8 4.8e-09 35.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EAU92433.1 - 3.6e-16 57.6 10.2 0.00016 20.8 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EAU92433.1 - 6.8e-16 57.6 20.6 1e-10 41.0 1.2 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EAU92433.1 - 1.5e-11 44.0 1.4 9.6e-05 22.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EAU92433.1 - 2.8e-08 33.4 7.2 0.00037 20.2 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 EAU92433.1 - 0.0014 18.2 0.3 0.028 13.9 0.0 2.6 1 1 1 3 3 3 1 Caleosin related protein DUF150 PF02576.12 EAU92433.1 - 0.061 12.8 1.8 0.9 9.1 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised BCR, YhbC family COG0779 SPARC_Ca_bdg PF10591.4 EAU92433.1 - 0.062 13.3 3.7 0.71 9.9 0.5 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Adaptin_binding PF10199.4 EAU92433.1 - 0.092 13.0 2.9 0.078 13.2 1.2 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Relaxase PF03432.9 EAU92433.1 - 0.12 11.7 2.9 0.13 11.6 1.1 1.7 1 1 1 2 2 2 0 Relaxase/Mobilisation nuclease domain IF2_N PF04760.10 EAU92433.1 - 0.14 11.8 1.1 10 5.8 0.0 3.0 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TerB PF05099.8 EAU92433.1 - 0.46 10.2 4.8 0.73 9.5 0.1 2.9 1 1 2 3 3 3 0 Tellurite resistance protein TerB CCDC-167 PF15188.1 EAU92433.1 - 1.3 8.9 4.8 0.64 9.9 1.7 1.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.20 EAU92435.1 - 1.5e-59 201.2 0.0 1.8e-34 119.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92435.1 - 1.3e-26 93.2 0.0 2.7e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EAU92435.1 - 0.00014 22.3 3.8 0.00014 22.3 2.7 3.2 2 1 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 EAU92435.1 - 0.00047 19.2 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EAU92435.1 - 0.055 12.4 0.0 0.96 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Hs1pro-1_C PF07014.7 EAU92435.1 - 0.3 10.3 0.0 0.49 9.6 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Alpha_kinase PF02816.13 EAU92438.2 - 1.1e-13 51.2 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family TauD PF02668.11 EAU92439.1 - 2.7e-49 168.1 0.0 3.7e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EAU92439.1 - 0.065 13.7 0.1 5 7.6 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Ribosomal_L21e PF01157.13 EAU92440.1 - 1.9e-38 130.2 3.8 4.9e-38 128.9 2.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Surface_Ag_2 PF01617.12 EAU92440.1 - 0.041 13.0 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Surface antigen Ribosomal_S4 PF00163.14 EAU92441.1 - 1.9e-27 95.4 1.3 3.5e-27 94.6 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EAU92441.1 - 4.8e-12 45.1 1.7 4.8e-12 45.1 1.2 2.9 3 0 0 3 3 3 1 S4 domain HHH_8 PF14716.1 EAU92442.1 - 2e-11 43.8 0.4 5.7e-10 39.2 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 EAU92442.1 - 5.1e-10 38.8 0.0 1.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EAU92442.1 - 1.2e-09 38.2 0.0 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EAU92442.1 - 2.5e-06 26.9 0.0 4.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EAU92442.1 - 0.0006 19.9 0.3 0.0013 18.8 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 EAU92442.1 - 0.021 14.4 0.4 0.081 12.6 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Raptor_N PF14538.1 EAU92443.2 - 1.4e-62 210.1 0.0 7e-62 207.8 0.0 2.1 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EAU92443.2 - 2e-11 43.2 14.4 4.3e-07 29.5 0.3 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 EAU92443.2 - 3.6e-05 23.4 1.7 0.00058 19.7 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EAU92443.2 - 7.6e-05 23.0 1.6 0.013 15.9 0.1 3.9 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EAU92443.2 - 0.00071 19.8 0.0 0.0034 17.6 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats Cohesin_HEAT PF12765.2 EAU92443.2 - 0.015 15.2 0.6 1.7 8.6 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Peptidase_C14 PF00656.17 EAU92443.2 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Caspase domain Dynactin PF12455.3 EAU92444.2 - 3.5e-88 295.1 7.0 3.5e-88 295.1 4.9 2.8 3 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 EAU92444.2 - 1.7e-24 85.2 1.4 5.1e-24 83.7 1.0 1.8 2 0 0 2 2 2 1 CAP-Gly domain CorA PF01544.13 EAU92445.2 - 5.7e-12 45.2 4.1 5.6e-07 28.8 0.1 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF4050 PF13259.1 EAU92446.2 - 0.05 13.5 0.3 0.098 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) GST_C PF00043.20 EAU92447.1 - 1.7e-09 37.5 0.0 3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAU92447.1 - 1.9e-09 37.5 0.0 3.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EAU92447.1 - 4.6e-09 36.3 0.0 1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU92447.1 - 6.3e-08 32.5 0.2 2.8e-07 30.4 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU92447.1 - 3.2e-05 23.7 0.0 7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EAU92448.2 - 0.0052 16.4 0.2 0.016 14.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 EAU92449.2 - 3.1e-12 45.9 0.0 1.7e-10 40.3 0.0 2.6 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 EAU92449.2 - 2.5e-05 23.9 0.0 0.00032 20.4 0.0 2.9 3 0 0 3 3 3 1 UBA/TS-N domain TPR_2 PF07719.12 EAU92449.2 - 0.00076 19.2 0.0 0.13 12.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 EAU92449.2 - 0.025 14.2 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain TPR_1 PF00515.23 EAU92449.2 - 0.064 12.8 0.0 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CorA PF01544.13 EAU92450.2 - 1e-25 90.3 11.0 1.1e-17 64.0 0.3 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Mhr1 PF12829.2 EAU92450.2 - 0.027 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination PRAP PF15314.1 EAU92457.1 - 0.53 10.6 2.9 1.1 9.6 0.2 2.1 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine Polysacc_deac_1 PF01522.16 EAU92458.2 - 4.5e-05 23.0 0.1 0.00024 20.6 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase F-box-like PF12937.2 EAU92459.1 - 2.7e-07 30.1 0.6 7.1e-07 28.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU92459.1 - 2.7e-06 26.8 0.3 1.2e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 EAU92459.1 - 0.053 13.2 0.3 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain zf-C2H2 PF00096.21 EAU92460.1 - 1.3e-08 34.6 13.9 0.00018 21.6 2.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU92460.1 - 9.5e-06 25.6 12.0 0.0091 16.2 1.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU92460.1 - 0.00025 21.1 6.7 0.00025 21.1 4.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain Ogr_Delta PF04606.7 EAU92460.1 - 0.024 14.3 1.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger FANCL_C PF11793.3 EAU92460.1 - 0.12 12.2 1.0 0.22 11.5 0.7 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain MSA-2c PF12238.3 EAU92460.1 - 0.14 11.7 0.2 0.14 11.7 0.1 3.2 2 1 0 2 2 2 0 Merozoite surface antigen 2c MIP-T3 PF10243.4 EAU92460.1 - 1 7.7 17.4 1.3 7.4 12.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-C2H2_jaz PF12171.3 EAU92460.1 - 8 6.7 7.2 0.62 10.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_33 PF13671.1 EAU92461.1 - 7.2e-17 61.6 0.2 3.7e-15 56.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain RNA_ligase PF09414.5 EAU92461.1 - 2.1e-09 37.4 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 RNA ligase Y_phosphatase PF00102.22 EAU92461.1 - 2e-06 27.3 0.0 3.3e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EAU92461.1 - 5.9e-05 23.3 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EAU92461.1 - 0.00087 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA_17 PF13207.1 EAU92461.1 - 0.0025 18.6 0.0 0.0087 16.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EAU92461.1 - 0.0037 16.6 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DSPc PF00782.15 EAU92461.1 - 0.01 15.4 0.0 0.034 13.7 0.0 1.9 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Zeta_toxin PF06414.7 EAU92461.1 - 0.034 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EAU92461.1 - 0.043 13.9 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CDKN3 PF05706.7 EAU92461.1 - 0.09 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_11 PF13414.1 EAU92461.1 - 0.094 12.3 0.3 0.21 11.2 0.2 1.6 1 0 0 1 1 1 0 TPR repeat AAA_5 PF07728.9 EAU92461.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PTPlike_phytase PF14566.1 EAU92461.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate 6PF2K PF01591.13 EAU92461.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RCC1 PF00415.13 EAU92462.1 - 1.1e-29 102.3 22.3 2e-06 27.8 0.8 8.1 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EAU92462.1 - 1.5e-19 69.0 23.8 5.7e-06 25.8 0.3 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat ABC_tran PF00005.22 EAU92463.2 - 5.4e-52 175.7 0.0 1.5e-27 96.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EAU92463.2 - 1.1e-28 100.3 37.3 1e-15 57.6 12.1 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EAU92463.2 - 7e-22 78.7 0.3 4.9e-08 33.2 0.0 4.6 4 0 0 4 4 4 4 AAA domain AAA_23 PF13476.1 EAU92463.2 - 5e-08 33.5 2.0 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EAU92463.2 - 2.5e-06 26.8 0.4 0.066 12.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EAU92463.2 - 4.4e-06 26.1 0.0 0.038 13.2 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EAU92463.2 - 0.00027 20.0 0.0 0.031 13.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.1 EAU92463.2 - 0.00043 20.7 0.0 1.3 9.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) DUF258 PF03193.11 EAU92463.2 - 0.0013 17.9 0.3 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EAU92463.2 - 0.01 15.4 1.3 11 5.5 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EAU92463.2 - 0.018 15.2 1.0 9.5 6.3 0.0 3.4 2 2 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAU92463.2 - 0.022 13.8 0.1 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MukB PF04310.7 EAU92463.2 - 0.047 13.0 0.3 11 5.2 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_25 PF13481.1 EAU92463.2 - 0.14 11.5 0.2 15 4.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 EAU92463.2 - 0.18 11.2 3.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EAU92463.2 - 0.37 10.1 3.3 13 5.1 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain ABC2_membrane PF01061.19 EAU92463.2 - 2.6 7.1 47.6 0.088 11.9 9.7 4.1 4 1 0 4 4 4 0 ABC-2 type transporter CRAL_TRIO PF00650.15 EAU92465.1 - 5.7e-37 126.6 0.0 7.7e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EAU92465.1 - 7.1e-05 22.7 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EAU92465.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Cu-oxidase_3 PF07732.10 EAU92467.2 - 1.2e-33 115.3 0.0 2.3e-30 104.7 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EAU92467.2 - 2.9e-27 95.5 0.0 4.2e-26 91.7 0.0 2.6 2 1 1 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU92467.2 - 9.8e-24 83.4 0.8 3.2e-21 75.2 0.0 3.4 3 1 0 3 3 3 2 Multicopper oxidase VPS28 PF03997.7 EAU92468.1 - 0.038 13.5 4.3 0.052 13.1 2.8 1.4 1 1 0 1 1 1 0 VPS28 protein DUF4606 PF15379.1 EAU92468.1 - 0.16 12.0 3.1 0.077 13.0 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Thioredoxin PF00085.15 EAU92470.1 - 1.7e-28 98.3 0.0 2e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EAU92470.1 - 1.6e-09 37.9 0.1 1.5e-08 34.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EAU92470.1 - 8.8e-08 32.1 0.0 7.4e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EAU92470.1 - 7.3e-06 25.5 0.0 8.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EAU92470.1 - 1.4e-05 24.6 0.1 0.0014 18.1 0.0 2.1 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EAU92470.1 - 4e-05 23.2 0.1 0.0022 17.6 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family DUF2847 PF11009.3 EAU92470.1 - 0.00016 21.2 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_7 PF13899.1 EAU92470.1 - 0.0014 18.6 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Flagellin_D3 PF08884.6 EAU92470.1 - 0.038 14.1 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Flagellin D3 domain Glutaredoxin PF00462.19 EAU92470.1 - 0.046 13.7 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.6 EAU92470.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.1 EAU92470.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DUF713 PF05218.9 EAU92470.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Cu-oxidase PF00394.17 EAU92471.1 - 1.4e-43 148.5 0.5 9.5e-43 145.8 0.0 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EAU92471.1 - 1.1e-41 141.2 0.3 2.7e-39 133.5 0.1 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EAU92471.1 - 1e-26 93.1 4.8 3.5e-23 81.6 0.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase DUF4625 PF15418.1 EAU92471.1 - 0.095 12.8 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Methyltransf_16 PF10294.4 EAU92473.1 - 1.6e-20 73.2 0.0 2.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAU92473.1 - 1e-09 38.9 0.0 1.9e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU92473.1 - 1.1e-06 28.3 0.0 2.6e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU92473.1 - 2.4e-05 24.7 0.0 6.4e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU92473.1 - 3.7e-05 23.7 0.0 8.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EAU92473.1 - 0.00017 20.8 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EAU92473.1 - 0.00026 20.7 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU92473.1 - 0.0014 19.0 0.0 0.0036 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EAU92473.1 - 0.0022 17.5 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EAU92473.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EAU92473.1 - 0.056 13.8 0.0 0.096 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EAU92473.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L2_C PF03947.13 EAU92475.1 - 6.8e-49 164.9 0.3 1.2e-48 164.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EAU92475.1 - 4.3e-26 90.6 0.3 7.5e-26 89.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TIP49 PF06068.8 EAU92476.1 - 4e-178 592.1 1.8 4.7e-178 591.9 1.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EAU92476.1 - 2e-09 37.7 0.2 2.9e-06 27.5 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EAU92476.1 - 2e-07 30.3 1.3 0.00027 20.0 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EAU92476.1 - 4.8e-05 23.5 0.2 0.2 11.7 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EAU92476.1 - 6e-05 23.1 0.0 0.00023 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.10 EAU92476.1 - 0.00021 20.2 0.2 0.00036 19.5 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.1 EAU92476.1 - 0.00055 19.3 0.3 0.0014 18.0 0.2 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EAU92476.1 - 0.0045 16.1 1.3 0.067 12.3 0.2 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 EAU92476.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_5 PF07728.9 EAU92476.1 - 0.027 14.2 1.8 8.7 6.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Aldo_ket_red PF00248.16 EAU92477.1 - 1.8e-64 217.2 0.0 2.4e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PUF PF00806.14 EAU92478.1 - 3.3e-28 95.5 0.0 1.7e-07 30.3 0.0 6.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat SR-25 PF10500.4 EAU92479.1 - 0.0048 16.3 4.9 0.0048 16.3 3.4 2.8 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein Aldo_ket_red PF00248.16 EAU92482.1 - 4.2e-70 235.7 0.0 5.1e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UDG PF03167.14 EAU92482.1 - 0.077 12.4 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Fasciclin PF02469.17 EAU92483.1 - 2.9e-08 33.7 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Metallophos_2 PF12850.2 EAU92485.1 - 5.9e-06 26.1 0.0 1.4e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EAU92485.1 - 0.0002 20.8 1.3 0.0004 19.8 0.9 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_N PF01602.15 EAU92486.2 - 1.2e-88 297.7 7.6 1.2e-88 297.7 5.3 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EAU92486.2 - 3.6e-65 217.5 0.0 1e-64 216.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EAU92486.2 - 1.2e-58 196.7 0.0 3.1e-58 195.4 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EAU92486.2 - 2.1e-13 50.3 8.1 2.6e-05 24.4 0.0 5.3 3 2 3 6 6 6 3 HEAT repeats HEAT PF02985.17 EAU92486.2 - 1.1e-10 40.6 2.9 0.023 14.7 0.0 6.4 5 1 1 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EAU92486.2 - 8e-05 22.9 1.1 0.8 10.2 0.0 5.3 4 2 2 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 EAU92486.2 - 0.00016 21.5 11.8 0.06 13.1 0.0 4.1 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 TrpBP PF02081.10 EAU92486.2 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein ParcG PF10274.4 EAU92486.2 - 0.018 14.9 4.2 0.57 10.0 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein Nramp PF01566.13 EAU92488.2 - 3.8e-86 289.0 17.4 3.8e-86 289.0 12.1 2.3 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Adap_comp_sub PF00928.16 EAU92490.2 - 1.6e-22 79.9 0.0 2.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EAU92490.2 - 5.3e-09 35.9 0.1 9.3e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ank_2 PF12796.2 EAU92491.1 - 9.3e-40 134.8 0.4 2.9e-12 46.7 0.0 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EAU92491.1 - 4.8e-36 120.7 3.7 8e-08 31.7 0.0 10.7 11 0 0 11 11 11 5 Ankyrin repeat Ank_4 PF13637.1 EAU92491.1 - 1e-34 118.3 3.7 1.6e-06 28.4 0.0 8.9 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU92491.1 - 1.7e-31 107.4 3.2 1.6e-07 31.3 0.0 7.8 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU92491.1 - 3.9e-25 85.3 1.3 0.031 14.4 0.0 11.4 10 1 0 10 10 10 6 Ankyrin repeat AAA_22 PF13401.1 EAU92491.1 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EAU92491.1 - 0.001 17.9 0.0 0.0025 16.7 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.7 EAU92491.1 - 0.0051 16.4 0.0 0.018 14.7 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU92491.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Muted PF14942.1 EAU92491.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Annexin PF00191.15 EAU92492.1 - 8.7e-27 92.8 2.5 4.5e-08 32.8 0.0 3.7 3 0 0 3 3 3 3 Annexin Annexin PF00191.15 EAU92494.2 - 4.4e-44 148.2 6.3 6.5e-17 61.1 0.1 4.9 4 1 0 4 4 4 4 Annexin Annexin PF00191.15 EAU92495.2 - 5.5e-25 87.0 0.5 4.1e-10 39.4 0.1 4.3 4 1 0 4 4 4 3 Annexin OrfB_Zn_ribbon PF07282.6 EAU92496.2 - 0.37 10.4 2.2 0.85 9.3 1.5 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Meiotic_rec114 PF03525.9 EAU92497.1 - 0.1 11.0 0.6 0.16 10.4 0.4 1.2 1 0 0 1 1 1 0 Meiotic recombination protein rec114 GreA_GreB_N PF03449.10 EAU92499.1 - 0.13 12.3 0.3 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF1759 PF03564.10 EAU92500.1 - 0.084 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Ank_2 PF12796.2 EAU92501.2 - 1.4e-33 115.0 1.6 4.4e-11 42.9 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EAU92501.2 - 4.3e-32 108.3 10.9 7.1e-06 25.5 0.0 10.2 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 EAU92501.2 - 7.8e-30 102.2 6.8 2.2e-07 30.9 0.0 6.6 5 2 1 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EAU92501.2 - 4.4e-29 100.3 5.5 0.001 19.5 0.0 9.3 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU92501.2 - 2.9e-22 76.5 2.9 0.0083 16.2 0.0 10.8 11 0 0 11 11 11 5 Ankyrin repeat AAA_22 PF13401.1 EAU92501.2 - 0.00023 21.2 0.0 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EAU92501.2 - 0.00098 18.0 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EAU92501.2 - 0.0049 16.5 0.0 0.019 14.6 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU92501.2 - 0.023 14.6 0.0 0.078 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain UPF0203 PF05254.7 EAU92502.1 - 6.4e-19 67.5 2.3 1.9e-18 66.0 1.6 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EAU92502.1 - 0.041 13.8 2.4 2.8 7.9 0.4 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF19 PF01579.13 EAU92502.1 - 0.079 12.9 1.0 0.11 12.4 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF19) DUF4515 PF14988.1 EAU92502.1 - 0.089 12.4 1.3 0.1 12.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) COX6B PF02297.12 EAU92502.1 - 0.11 12.5 5.6 2 8.4 0.0 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF488 PF04343.8 EAU92502.1 - 0.11 12.8 0.3 0.14 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF488 CHCH PF06747.8 EAU92502.1 - 3.8 7.5 5.4 1.1 9.2 1.3 1.8 2 0 0 2 2 2 0 CHCH domain Gal-bind_lectin PF00337.17 EAU92504.1 - 1.5e-07 30.7 0.0 1.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Galactoside-binding lectin Nucleoplasmin PF03066.10 EAU92505.2 - 0.00069 19.1 3.1 0.0011 18.5 2.1 1.3 1 0 0 1 1 1 1 Nucleoplasmin Nop14 PF04147.7 EAU92505.2 - 0.053 11.4 7.0 0.083 10.8 4.8 1.2 1 0 0 1 1 1 0 Nop14-like family Man-6-P_recep PF02157.10 EAU92505.2 - 0.083 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Totivirus_coat PF05518.6 EAU92505.2 - 2.5 5.7 8.9 3.3 5.4 6.2 1.2 1 0 0 1 1 1 0 Totivirus coat protein Cwf_Cwc_15 PF04889.7 EAU92505.2 - 4.4 6.9 10.4 7.6 6.1 7.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 EAU92505.2 - 4.5 6.8 12.8 7.5 6.1 8.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 EAU92505.2 - 10 5.0 9.6 16 4.4 6.7 1.2 1 0 0 1 1 1 0 BUD22 Complex1_49kDa PF00346.14 EAU92506.2 - 2.1e-113 377.8 0.0 3e-113 377.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EAU92506.2 - 0.026 13.2 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Nickel-dependent hydrogenase NIF3 PF01784.13 EAU92507.2 - 2.3e-49 168.1 0.0 3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ETF PF01012.16 EAU92507.2 - 0.062 13.0 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Electron transfer flavoprotein domain TPX2 PF06886.6 EAU92509.1 - 2.4e-08 33.9 19.7 2.4e-08 33.9 13.6 2.1 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) ECH PF00378.15 EAU92510.1 - 1e-52 178.7 0.0 1.2e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Glutaredoxin PF00462.19 EAU92516.1 - 4.3e-18 65.0 0.1 6.3e-18 64.5 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EAU92516.1 - 0.0018 18.4 0.4 0.0072 16.5 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EAU92516.1 - 0.0047 16.4 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EAU92516.1 - 0.0056 16.6 0.1 0.0099 15.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EAU92516.1 - 0.025 14.4 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain DUF836 PF05768.9 EAU92516.1 - 0.032 14.5 0.1 0.038 14.2 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.1 EAU92516.1 - 0.034 14.3 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SIS PF01380.17 EAU92518.1 - 0.16 11.6 0.0 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 SIS domain Yae1_N PF09811.4 EAU92521.2 - 7.8e-11 41.3 6.7 1.2e-10 40.7 4.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF1115 PF06544.7 EAU92522.1 - 2.6e-10 40.0 0.0 6.3e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.13 EAU92522.1 - 0.081 13.0 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Acylphosphatase Aminotran_1_2 PF00155.16 EAU92523.2 - 1.8e-41 142.3 0.0 2.7e-41 141.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EAU92523.2 - 0.0059 15.6 0.1 0.012 14.7 0.1 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EAU92523.2 - 0.0076 14.5 0.0 0.016 13.4 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EAU92523.2 - 0.03 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 EAU92523.2 - 0.035 12.8 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V ZZ PF00569.12 EAU92526.1 - 5e-24 83.5 35.2 4.5e-09 35.7 3.1 3.3 3 0 0 3 3 3 3 Zinc finger, ZZ type PB1 PF00564.19 EAU92526.1 - 0.0075 15.9 0.0 0.032 13.8 0.0 2.2 2 1 0 2 2 2 1 PB1 domain C1_2 PF03107.11 EAU92526.1 - 4.2 7.5 43.0 5.7 7.1 9.0 3.4 3 0 0 3 3 3 0 C1 domain WD40 PF00400.27 EAU92527.1 - 5.7e-74 241.5 20.4 9.8e-09 34.7 0.2 10.9 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 EAU92527.1 - 2.9e-42 143.6 0.0 5.5e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 EAU92527.1 - 0.002 16.9 5.6 1.9 7.1 0.1 5.7 2 2 4 6 6 6 1 Nup133 N terminal like Fork_head PF00250.13 EAU92528.2 - 1.6e-19 69.7 0.0 2.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Fork head domain ATG16 PF08614.6 EAU92528.2 - 0.02 14.7 4.2 0.034 13.9 2.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Vac_Fusion PF02346.11 EAU92528.2 - 0.11 11.8 0.6 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Fungal_trans PF04082.13 EAU92529.2 - 2.2e-39 134.9 0.0 3.3e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NIPSNAP PF07978.8 EAU92530.1 - 5.5e-26 90.5 0.2 6.7e-26 90.2 0.1 1.1 1 0 0 1 1 1 1 NIPSNAP DUF953 PF06110.6 EAU92534.1 - 1.8e-18 66.1 0.0 2e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 EAU92534.1 - 0.00025 20.6 0.0 0.00046 19.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EAU92534.1 - 0.027 14.6 0.3 0.14 12.3 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EAU92534.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Dynactin_p22 PF07426.6 EAU92535.1 - 0.3 10.3 1.6 0.4 9.9 0.3 1.7 2 0 0 2 2 2 0 Dynactin subunit p22 Mito_carr PF00153.22 EAU92536.2 - 7.4e-69 227.5 1.1 3.3e-26 90.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EAU92536.2 - 1.4e-15 55.3 6.9 6.2e-07 28.2 0.1 5.8 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.1 EAU92536.2 - 1.5e-14 53.8 5.6 6.1e-05 23.0 0.4 5.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EAU92536.2 - 3.4e-14 51.3 6.1 3.5e-05 23.3 0.1 5.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 EAU92536.2 - 2.4e-11 43.0 1.4 0.0014 18.2 0.0 5.4 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EAU92536.2 - 1.3e-08 33.7 4.1 2.7e-05 23.2 0.0 3.8 3 0 0 3 3 3 2 EF hand Met_10 PF02475.11 EAU92537.2 - 2.8e-69 232.7 0.0 4.4e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EAU92537.2 - 3.1e-05 23.9 0.0 0.00078 19.4 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.10 EAU92537.2 - 0.00056 19.4 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.2 EAU92537.2 - 0.011 16.3 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 EAU92537.2 - 0.024 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TatD_DNase PF01026.16 EAU92538.1 - 5e-29 101.2 0.0 6.8e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Lgl_C PF08596.5 EAU92540.2 - 1.6e-34 119.0 0.0 3.1e-33 114.8 0.0 2.6 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EAU92540.2 - 1.5e-07 30.9 0.5 0.0012 18.6 0.1 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Myosin_tail_1 PF01576.14 EAU92541.2 - 4.3 4.9 222.2 0.026 12.2 36.2 6.3 2 1 5 7 7 7 0 Myosin tail DUF89 PF01937.14 EAU92542.1 - 9.7e-106 353.5 0.0 1.2e-105 353.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 zf-RING_2 PF13639.1 EAU92543.2 - 1.4e-12 47.2 5.4 1.4e-12 47.2 3.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EAU92543.2 - 2.5e-11 43.5 6.0 2.9e-11 43.3 0.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_3 PF14369.1 EAU92543.2 - 1.5e-06 28.0 4.1 2.5e-06 27.3 1.0 2.6 2 0 0 2 2 2 1 zinc-finger zf-C3HC4 PF00097.20 EAU92543.2 - 2.5e-06 27.0 6.3 2.5e-06 27.0 4.4 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU92543.2 - 4.9e-06 26.1 10.0 1.1e-05 25.0 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU92543.2 - 6.4e-06 25.8 4.1 6.4e-06 25.8 2.8 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EAU92543.2 - 2.9e-05 23.8 0.4 2.9e-05 23.8 0.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EAU92543.2 - 8.3e-05 22.5 6.4 8.3e-05 22.5 4.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EAU92543.2 - 0.15 12.0 4.8 0.75 9.7 3.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EAU92543.2 - 2.2 8.0 7.5 1.5 8.5 3.1 2.3 1 1 1 2 2 2 0 RING-type zinc-finger PHD PF00628.24 EAU92543.2 - 6.4 6.5 14.7 0.41 10.3 2.6 2.6 3 0 0 3 3 3 0 PHD-finger Gcd10p PF04189.8 EAU92549.2 - 1.3e-61 208.3 0.0 1.2e-58 198.5 0.0 2.1 1 1 1 2 2 2 2 Gcd10p family PXA PF02194.10 EAU92550.2 - 3.4e-50 170.1 0.1 9.8e-50 168.6 0.1 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EAU92550.2 - 1.5e-28 99.1 1.2 4e-28 97.7 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EAU92550.2 - 3.4e-15 55.8 0.0 1.6e-14 53.6 0.0 2.1 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EAU92550.2 - 2.8e-11 43.5 0.2 1.1e-10 41.5 0.2 2.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain IncA PF04156.9 EAU92550.2 - 0.63 9.6 13.3 0.91 9.0 0.4 2.6 2 0 0 2 2 2 0 IncA protein Mito_carr PF00153.22 EAU92551.2 - 6.1e-59 195.7 1.1 4.4e-20 71.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.13 EAU92552.1 - 3.1e-12 46.2 4.1 3.1e-12 46.2 2.8 1.7 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 EAU92553.1 - 2.2e-12 46.8 1.5 4.4e-12 45.7 0.0 2.1 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) UDPGP PF01704.13 EAU92554.1 - 1.2e-49 168.9 0.0 1.6e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EAU92554.1 - 0.0035 17.4 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Taxilin PF09728.4 EAU92555.1 - 2.7e-18 66.1 31.4 1.4e-10 40.7 2.3 2.7 2 1 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 EAU92555.1 - 7e-08 32.0 0.6 0.0033 17.0 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Cupin_6 PF12852.2 EAU92555.1 - 0.024 14.2 0.3 0.16 11.5 0.1 2.3 2 0 0 2 2 2 0 Cupin DUF3772 PF12607.3 EAU92555.1 - 0.18 11.4 4.2 0.8 9.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) Presenilin PF01080.12 EAU92555.1 - 3.1 6.5 6.1 6.1 5.5 4.2 1.4 1 0 0 1 1 1 0 Presenilin BRCA-2_OB1 PF09103.5 EAU92556.2 - 4.4e-32 110.2 0.0 7.9e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EAU92556.2 - 3.4e-05 23.4 0.1 6.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 BRCA2, helical DUF566 PF04484.7 EAU92557.2 - 1.7 8.0 9.6 2.2 7.7 6.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) PAT1 PF09770.4 EAU92557.2 - 8.4 4.4 12.1 11 4.1 8.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M16 PF00675.15 EAU92558.1 - 7.5e-38 129.6 0.0 1.5e-37 128.5 0.0 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EAU92558.1 - 1.1e-36 126.1 0.0 3.1e-36 124.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase M16 inactive domain Ceramidase PF05875.7 EAU92559.2 - 5.4e-60 202.7 0.4 6.8e-60 202.4 0.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF423 PF04241.10 EAU92559.2 - 0.6 10.0 5.4 3 7.8 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF423) EF_TS PF00889.14 EAU92560.1 - 2.2e-19 69.6 0.0 5.3e-18 65.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.26 EAU92560.1 - 8.1e-06 25.5 0.0 2.2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Hormone_1 PF00103.15 EAU92560.1 - 0.066 12.5 0.1 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Somatotropin hormone family Gar1 PF04410.9 EAU92561.1 - 2.1e-30 105.2 0.3 2.1e-30 105.2 0.2 2.9 3 1 0 3 3 3 1 Gar1/Naf1 RNA binding region Daxx PF03344.10 EAU92561.1 - 0.23 9.8 12.4 0.4 9.0 8.6 1.3 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 EAU92561.1 - 2.6 6.2 7.6 3.7 5.7 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein F-box-like PF12937.2 EAU92562.1 - 0.0014 18.3 0.2 0.0036 16.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like SAS4 PF15460.1 EAU92563.1 - 0.00027 20.7 4.6 0.00066 19.4 3.2 1.7 1 1 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 EAU92563.1 - 0.019 15.4 1.2 0.019 15.4 0.9 3.3 2 1 2 4 4 4 0 PEHE domain PCP_red PF08369.5 EAU92564.2 - 0.034 14.0 0.9 0.08 12.8 0.6 1.6 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Nucleo_P87 PF07267.6 EAU92564.2 - 3.6 6.1 5.7 4.4 5.8 4.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 zf-DHHC PF01529.15 EAU92565.2 - 1.5e-40 138.4 6.8 3e-40 137.4 4.7 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase TSNR_N PF04705.7 EAU92566.2 - 0.051 13.3 0.4 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus Vac_Fusion PF02346.11 EAU92566.2 - 0.19 11.1 4.2 0.31 10.4 0.3 2.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein RNase_HII PF01351.13 EAU92566.2 - 1.2 8.7 6.5 3.6 7.1 0.1 3.1 2 1 0 2 2 2 0 Ribonuclease HII DUF972 PF06156.8 EAU92566.2 - 1.6 9.1 9.7 2.5 8.4 3.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EAU92566.2 - 1.7 7.0 16.1 0.7 8.2 8.5 2.0 2 0 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 EAU92566.2 - 2.1 8.1 20.7 3 7.7 0.1 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.1 EAU92566.2 - 2.6 8.0 22.5 0.13 12.2 8.4 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.6 EAU92566.2 - 5.9 6.6 9.5 16 5.2 0.1 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 CutC PF03932.9 EAU92567.2 - 2.1e-39 134.9 0.0 2.7e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 CutC family FA_desaturase PF00487.19 EAU92568.2 - 3.9e-08 33.0 1.8 6.8e-08 32.2 1.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EAU92568.2 - 7.9e-05 22.3 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Methyltransf_23 PF13489.1 EAU92569.1 - 1.6e-08 34.4 0.0 2.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU92569.1 - 5.1e-08 33.4 0.3 5.2e-07 30.2 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU92569.1 - 4.9e-07 29.4 0.0 2.3e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU92569.1 - 6.5e-07 29.7 0.0 2.2e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU92569.1 - 1.3e-05 25.5 0.0 3.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EAU92569.1 - 0.00013 21.0 0.0 0.00036 19.6 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EAU92569.1 - 0.00056 20.2 0.0 0.0036 17.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAU92569.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EAU92569.1 - 0.017 14.2 0.0 4 6.4 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EAU92569.1 - 0.046 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EAU92569.1 - 0.062 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Adaptin_N PF01602.15 EAU92570.2 - 6.1e-107 358.1 3.0 9.7e-107 357.4 2.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EAU92570.2 - 7.8e-10 38.9 0.2 1.5e-05 25.1 0.0 5.0 5 1 1 6 6 6 3 HEAT repeats Cnd1 PF12717.2 EAU92570.2 - 8e-07 29.0 0.9 0.0021 17.9 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EAU92570.2 - 1.8e-06 27.5 4.3 0.016 15.2 0.1 5.6 5 0 0 5 5 5 1 HEAT repeat Nipped-B_C PF12830.2 EAU92570.2 - 0.0063 16.1 1.1 3.4 7.2 0.0 3.5 3 1 1 4 4 4 2 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.1 EAU92570.2 - 0.009 16.4 11.9 13 6.3 0.0 7.1 7 3 3 10 10 10 1 HEAT-like repeat Proteasom_PSMB PF10508.4 EAU92570.2 - 0.024 12.9 0.3 0.78 7.9 0.1 2.7 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 EAU92570.2 - 0.061 13.2 3.6 7.4 6.5 0.0 4.5 4 1 2 6 6 6 0 V-ATPase subunit H RasGEF_N_2 PF14663.1 EAU92570.2 - 0.085 12.8 3.0 0.35 10.8 0.0 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.18 EAU92570.2 - 0.74 9.7 4.3 29 4.6 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RhoGEF PF00621.15 EAU92571.2 - 1.5e-08 34.7 0.0 7.4e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 RhoGEF domain Vps51 PF08700.6 EAU92572.2 - 5.6e-17 61.3 2.2 1.6e-16 59.8 1.5 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EAU92572.2 - 2.5e-07 30.6 0.9 8e-07 29.0 0.6 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sel1 PF08238.7 EAU92573.2 - 2.8e-42 142.1 26.3 3.6e-08 33.7 0.2 8.0 8 0 0 8 8 8 7 Sel1 repeat Exo5 PF09810.4 EAU92574.2 - 5.4e-53 180.3 0.0 3.8e-44 151.2 0.0 2.9 1 1 1 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.15 EAU92574.2 - 0.16 11.6 5.4 1.1 8.9 1.6 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif DUF1349 PF07081.6 EAU92575.1 - 6e-17 61.5 0.0 7e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF1349 PF07081.6 EAU92576.1 - 1.9e-18 66.4 0.0 2.3e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Isochorismatase PF00857.15 EAU92579.1 - 2.2e-25 89.5 0.4 4.2e-25 88.6 0.3 1.4 1 1 0 1 1 1 1 Isochorismatase family AFOR_N PF02730.10 EAU92579.1 - 0.0033 16.7 0.0 0.0051 16.1 0.0 1.3 1 0 0 1 1 1 1 Aldehyde ferredoxin oxidoreductase, N-terminal domain OB_NTP_bind PF07717.11 EAU92580.2 - 3.3e-30 104.2 0.0 7.1e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EAU92580.2 - 2.8e-29 101.1 0.1 2.8e-29 101.1 0.1 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAU92580.2 - 1.5e-12 47.1 0.0 5.1e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EAU92580.2 - 1.2e-08 34.9 0.3 3.1e-08 33.6 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EAU92580.2 - 3.3e-06 26.7 0.0 7.4e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EAU92580.2 - 0.00014 20.8 0.0 0.00037 19.5 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EAU92580.2 - 0.00017 21.9 0.4 0.65 10.2 0.0 3.6 2 1 1 3 3 3 1 ABC transporter AAA_22 PF13401.1 EAU92580.2 - 0.00029 21.0 0.0 0.00094 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU92580.2 - 0.0011 18.6 0.2 0.0028 17.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EAU92580.2 - 0.0024 17.4 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zot PF05707.7 EAU92580.2 - 0.018 14.5 0.0 0.046 13.1 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_25 PF13481.1 EAU92580.2 - 0.046 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EAU92580.2 - 0.077 11.9 0.1 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Herpes_ori_bp PF02399.10 EAU92580.2 - 0.15 9.9 0.0 0.24 9.3 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein NTF2 PF02136.15 EAU92581.1 - 3.8e-12 46.6 0.0 5.9e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EAU92581.1 - 4.3e-10 39.6 0.0 5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Exo_endo_phos PF03372.18 EAU92582.2 - 6e-21 75.5 0.1 8e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1700 PF08006.6 EAU92582.2 - 0.1 11.8 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3285 PF11688.3 EAU92582.2 - 0.52 9.9 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) DUF2244 PF10003.4 EAU92582.2 - 0.99 8.7 3.7 1.9 7.8 2.6 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Abhydrolase_3 PF07859.8 EAU92583.1 - 1.8e-46 158.3 0.3 7.9e-46 156.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU92583.1 - 3.8e-16 58.7 0.0 9.5e-16 57.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAU92583.1 - 2.6e-05 23.9 0.0 4.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EAU92583.1 - 0.0033 16.2 0.0 1.4 7.5 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Ctr PF04145.10 EAU92588.2 - 1.5e-06 28.3 1.0 1.5e-06 28.3 0.7 1.6 2 0 0 2 2 2 1 Ctr copper transporter family Pkinase PF00069.20 EAU92589.2 - 2.3e-23 82.6 0.0 3.7e-15 55.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92589.2 - 1.1e-17 64.0 0.0 1.5e-09 37.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAU92589.2 - 0.068 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribonuc_L-PSP PF01042.16 EAU92592.1 - 4.4e-37 126.5 0.1 5e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP HEAT_2 PF13646.1 EAU92593.2 - 3.2e-05 24.1 0.1 0.047 13.9 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.18 EAU92593.2 - 0.00086 19.0 3.7 0.0065 16.2 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EAU92593.2 - 0.00089 19.6 0.7 1.2 9.7 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat RIX1 PF08167.7 EAU92593.2 - 0.019 14.6 0.0 0.08 12.6 0.0 2.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 EAU92593.2 - 0.46 8.6 2.8 5.9 5.0 0.0 2.6 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT PF02985.17 EAU92593.2 - 0.51 10.5 8.8 19 5.6 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat PAP2 PF01569.16 EAU92594.1 - 0.052 13.2 0.4 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 PAP2 superfamily Sugar_tr PF00083.19 EAU92594.1 - 0.054 12.0 0.3 0.081 11.4 0.2 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter PLAC8 PF04749.12 EAU92594.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 PLAC8 family PAH PF02671.16 EAU92595.2 - 2.1e-41 139.2 8.3 7.6e-15 54.2 0.0 4.3 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EAU92595.2 - 4.6e-37 125.8 0.0 1.1e-36 124.6 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor COX5A PF02284.11 EAU92595.2 - 0.019 14.9 0.1 3.8 7.5 0.0 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va Rsbr_N PF08678.5 EAU92596.2 - 0.0044 16.9 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Rsbr N terminal PAH PF02671.16 EAU92597.1 - 1.7e-06 27.5 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat PAH PF02671.16 EAU92598.1 - 3.9e-10 39.1 0.0 5.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat Utp21 PF04192.7 EAU92599.2 - 0.051 12.6 0.9 0.096 11.7 0.6 1.4 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain SUR7 PF06687.7 EAU92600.1 - 1.3e-15 57.5 17.4 1.7e-15 57.1 12.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Arginase PF00491.16 EAU92601.2 - 4.3e-64 216.4 0.0 6.2e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family Methyltransf_11 PF08241.7 EAU92602.2 - 1.6e-12 47.7 0.0 6.1e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU92602.2 - 8.3e-09 35.1 0.0 1.4e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU92602.2 - 2.6e-08 33.7 0.0 5.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU92602.2 - 3.6e-08 33.9 0.0 7.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU92602.2 - 8.2e-06 26.1 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU92602.2 - 1.2e-05 25.6 0.0 4.8e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EAU92602.2 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EAU92602.2 - 0.0031 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EAU92602.2 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EAU92602.2 - 0.0057 16.6 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EAU92602.2 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase HTH_8 PF02954.14 EAU92602.2 - 0.025 14.1 2.3 18 5.0 0.2 4.0 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family Methyltransf_32 PF13679.1 EAU92602.2 - 0.18 11.4 0.1 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain SF3b10 PF07189.6 EAU92603.2 - 6.6e-29 99.5 0.0 7.7e-29 99.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF1635 PF07795.6 EAU92604.2 - 0.031 13.6 2.1 0.046 13.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Nop14 PF04147.7 EAU92604.2 - 0.23 9.3 13.5 0.28 9.0 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.8 EAU92604.2 - 0.32 10.1 10.6 0.084 12.0 5.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) Sporozoite_P67 PF05642.6 EAU92604.2 - 0.77 7.5 10.4 0.92 7.2 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ebola_NP PF05505.7 EAU92604.2 - 5.2 5.0 9.8 6.8 4.6 6.8 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein LRR_6 PF13516.1 EAU92605.1 - 6.1e-07 28.8 11.7 0.39 10.9 0.1 7.5 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.2 EAU92605.1 - 2e-06 27.4 0.0 7.5e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EAU92605.1 - 0.0033 17.2 13.1 1.5 9.1 0.3 6.5 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.2 EAU92605.1 - 0.032 13.8 15.7 3.4 7.4 0.0 5.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EAU92605.1 - 0.046 13.3 0.1 0.046 13.3 0.1 3.0 3 0 0 3 3 3 0 F-box domain FAST_1 PF06743.10 EAU92605.1 - 0.051 13.2 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 LRR_7 PF13504.1 EAU92605.1 - 3 8.4 15.5 19 6.0 0.3 6.8 8 0 0 8 8 8 0 Leucine rich repeat YABBY PF04690.8 EAU92606.1 - 2e-08 34.6 0.2 2.2e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.14 EAU92606.1 - 3.6e-05 23.9 1.9 5.2e-05 23.4 1.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box DUF1014 PF06244.7 EAU92606.1 - 8.4e-05 22.7 1.4 9e-05 22.6 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box_2 PF09011.5 EAU92606.1 - 0.00033 20.9 0.4 0.00033 20.9 0.3 1.5 2 0 0 2 2 2 1 HMG-box domain Sec1 PF00995.18 EAU92607.2 - 8e-116 387.9 0.0 9.9e-116 387.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family cNMP_binding PF00027.24 EAU92608.1 - 2e-42 142.8 0.0 4.9e-17 61.5 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EAU92608.1 - 2.5e-19 70.0 3.1 1.4e-12 47.9 1.3 2.7 2 0 0 2 2 2 2 Patatin-like phospholipase ICL PF00463.16 EAU92609.2 - 1.9e-202 673.1 0.0 2.2e-202 672.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EAU92609.2 - 1.1e-11 44.4 0.1 3.1e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Homeobox PF00046.24 EAU92613.1 - 5.4e-46 154.0 13.0 7.2e-16 57.5 2.5 3.4 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 EAU92613.1 - 1.3e-15 56.8 2.7 2.6e-06 27.0 0.2 4.0 3 1 1 4 4 4 3 Homeobox KN domain HTH_3 PF01381.17 EAU92613.1 - 0.00013 21.7 0.3 0.68 9.8 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix HTH_26 PF13443.1 EAU92613.1 - 0.027 14.6 0.9 48 4.2 0.0 3.5 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain MafB19-deam PF14437.1 EAU92613.1 - 0.23 11.1 2.2 0.37 10.4 0.5 1.9 2 0 0 2 2 2 0 MafB19-like deaminase Fumble PF03630.9 EAU92614.1 - 9.2e-118 392.9 0.0 2.7e-89 299.3 0.0 3.0 3 0 0 3 3 3 3 Fumble Adaptin_N PF01602.15 EAU92615.1 - 1.6e-113 379.8 0.0 2.4e-113 379.2 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EAU92615.1 - 3.7e-59 198.8 1.6 8.5e-59 197.7 1.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EAU92615.1 - 2.7e-13 50.0 8.1 0.00021 21.4 0.0 6.3 3 2 4 7 7 7 3 HEAT repeats HEAT PF02985.17 EAU92615.1 - 0.00027 20.7 6.1 5.2 7.4 0.1 5.9 5 0 0 5 5 5 2 HEAT repeat HEAT_PBS PF03130.11 EAU92615.1 - 0.072 13.5 4.2 4.7 7.9 0.0 5.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EAU92615.1 - 1.8 9.1 9.5 7.5 7.1 0.2 4.0 3 1 1 4 4 4 0 HEAT-like repeat Pkinase PF00069.20 EAU92616.1 - 1e-37 129.7 0.0 1.3e-37 129.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92616.1 - 2.3e-13 49.8 0.0 3e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU92616.1 - 5.9e-05 22.9 0.0 0.0027 17.4 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EAU92616.1 - 0.015 14.1 0.1 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EAU92616.1 - 0.1 11.6 0.4 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chitin_synth_1 PF01644.12 EAU92617.2 - 1.2e-77 259.2 0.4 1.9e-77 258.6 0.3 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EAU92617.2 - 2e-25 88.2 0.0 5.1e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EAU92617.2 - 7.6e-24 83.9 0.1 5.8e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EAU92617.2 - 3.9e-08 33.2 0.7 3.9e-08 33.2 0.5 2.2 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EAU92617.2 - 1.2e-07 31.8 0.0 6.6e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Peptidase_M50 PF02163.17 EAU92617.2 - 0.082 11.8 0.7 3.2 6.6 0.0 2.9 3 1 0 3 3 3 0 Peptidase family M50 Glyco_hydro_16 PF00722.16 EAU92620.1 - 9.5e-07 28.2 0.3 1.9e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 BAG PF02179.11 EAU92621.1 - 6.7e-06 26.1 0.1 2.7e-05 24.1 0.1 2.0 1 0 0 1 1 1 1 BAG domain Nuf2 PF03800.9 EAU92622.2 - 1.9e-28 99.3 0.1 6.1e-28 97.6 0.1 1.9 1 0 0 1 1 1 1 Nuf2 family GTPase_Cys_C PF12631.2 EAU92622.2 - 0.38 11.1 9.9 14 6.1 3.3 3.8 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE GAS PF13851.1 EAU92622.2 - 0.78 8.8 52.7 0.11 11.6 11.6 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 EAU92622.2 - 2.3 5.4 50.9 0.087 10.1 14.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EAU92622.2 - 3.1 7.5 45.7 21 4.8 0.1 4.4 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EAU92622.2 - 5.5 5.9 50.7 7.3 5.5 7.8 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 Filament PF00038.16 EAU92622.2 - 6 6.2 53.2 0.6 9.5 29.3 2.4 1 1 1 2 2 2 0 Intermediate filament protein F-box PF00646.28 EAU92623.2 - 0.086 12.5 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 F-box domain GYF PF02213.11 EAU92624.1 - 2e-16 59.3 0.6 6e-16 57.7 0.3 2.0 2 0 0 2 2 2 1 GYF domain Acatn PF13000.2 EAU92625.1 - 1.5e-132 442.9 31.9 1.9e-64 218.1 11.8 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3139 PF11337.3 EAU92625.1 - 0.093 13.0 0.0 0.43 10.8 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) p450 PF00067.17 EAU92626.1 - 1.1e-56 192.3 0.0 1.4e-56 191.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RCR PF12273.3 EAU92627.2 - 0.058 13.9 0.1 0.13 12.8 0.1 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Syndecan PF01034.15 EAU92627.2 - 0.068 12.8 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain DUF4328 PF14219.1 EAU92627.2 - 0.071 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) ATP11 PF06644.6 EAU92629.2 - 4.8e-68 229.5 0.0 4.8e-68 229.5 0.0 2.0 1 1 1 2 2 2 1 ATP11 protein LMBR1 PF04791.11 EAU92629.2 - 0.28 9.7 0.3 0.36 9.3 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4551 PF15087.1 EAU92629.2 - 2.4 6.4 14.5 3.2 6.0 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BPL_LplA_LipB PF03099.14 EAU92630.2 - 1.2e-07 31.7 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ammonium_transp PF00909.16 EAU92631.2 - 1.3e-113 379.4 25.5 1.6e-113 379.2 17.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Prenylcys_lyase PF07156.9 EAU92632.2 - 1.4e-39 136.0 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EAU92632.2 - 1.7e-08 34.3 0.2 4.8e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EAU92632.2 - 1.5e-05 24.1 0.1 0.0043 16.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EAU92632.2 - 0.00056 19.7 0.0 0.0031 17.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EAU92632.2 - 0.0013 18.5 0.1 0.08 12.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU92632.2 - 0.0018 18.3 0.0 2.5 8.0 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EAU92632.2 - 0.0024 16.9 0.0 0.23 10.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DUF3576 PF12100.3 EAU92632.2 - 0.13 12.3 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3576) F-box-like PF12937.2 EAU92633.2 - 1.7e-05 24.4 0.4 1.7e-05 24.4 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU92633.2 - 5.8e-05 22.6 0.3 0.00018 21.0 0.2 1.9 1 0 0 1 1 1 1 F-box domain DLH PF01738.13 EAU92634.2 - 2.6e-13 49.7 0.0 3.1e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU92634.2 - 0.034 13.9 0.0 0.051 13.3 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family SARA PF11409.3 EAU92634.2 - 0.11 12.4 1.6 0.25 11.2 1.1 1.6 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) VirD1 PF07328.6 EAU92636.1 - 0.091 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Las1 PF04031.8 EAU92637.2 - 5e-44 149.6 0.1 1.1e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 Las1-like SprB PF13573.1 EAU92638.2 - 0.026 14.1 1.4 0.074 12.6 0.1 2.4 2 0 0 2 2 2 0 SprB repeat SKG6 PF08693.5 EAU92638.2 - 0.14 11.4 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF500 PF04366.7 EAU92639.2 - 2.6e-38 130.2 0.0 4.6e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_9 PF14604.1 EAU92639.2 - 0.0036 16.8 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EAU92639.2 - 0.026 14.0 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 0 Variant SH3 domain PIG-Y PF15159.1 EAU92639.2 - 0.092 12.9 0.1 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PIF1 PF05970.9 EAU92642.2 - 1.3e-57 195.3 0.0 1.5e-45 155.7 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EAU92642.2 - 3.2e-14 52.9 0.0 1.6e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU92642.2 - 5.8e-08 32.9 0.0 2e-07 31.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EAU92642.2 - 1.2e-05 25.0 0.2 2.7e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EAU92642.2 - 5.2e-05 23.3 0.0 0.00019 21.5 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EAU92642.2 - 0.00039 18.3 0.0 0.00072 17.4 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 EAU92642.2 - 0.00065 19.7 0.4 0.0026 17.7 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain PhoH PF02562.11 EAU92642.2 - 0.0012 18.0 0.2 0.0041 16.3 0.0 2.0 3 0 0 3 3 1 1 PhoH-like protein DAP3 PF10236.4 EAU92642.2 - 0.002 17.1 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 EAU92642.2 - 0.0048 16.5 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 EAU92642.2 - 0.0088 15.7 0.1 2.2 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 EAU92642.2 - 0.011 15.2 0.0 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase ABC_tran PF00005.22 EAU92642.2 - 0.012 15.9 0.6 0.035 14.3 0.1 2.1 2 0 0 2 2 1 0 ABC transporter T2SE PF00437.15 EAU92642.2 - 0.014 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EAU92642.2 - 0.019 15.1 0.2 0.069 13.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EAU92642.2 - 0.027 14.0 2.9 2.7 7.5 0.0 3.4 3 1 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.13 EAU92642.2 - 0.027 13.9 0.1 5.4 6.4 0.0 3.3 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EAU92642.2 - 0.03 13.7 0.3 0.1 12.0 0.0 2.0 3 0 0 3 3 3 0 AAA-like domain Helicase_RecD PF05127.9 EAU92642.2 - 0.038 13.6 0.1 0.18 11.4 0.1 2.1 1 1 0 1 1 1 0 Helicase AAA_29 PF13555.1 EAU92642.2 - 0.048 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EAU92642.2 - 0.061 12.7 0.1 0.58 9.5 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.4 EAU92642.2 - 0.067 11.7 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 EAU92642.2 - 0.07 12.8 0.3 0.25 10.9 0.0 2.0 2 1 0 2 2 1 0 Archaeal ATPase Mg_chelatase PF01078.16 EAU92642.2 - 0.075 12.1 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EAU92642.2 - 0.085 12.5 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 NTPase MMR_HSR1 PF01926.18 EAU92642.2 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EAU92642.2 - 0.11 12.2 0.1 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EAU92642.2 - 0.17 12.0 0.0 0.61 10.2 0.0 2.1 1 1 0 1 1 1 0 RNA helicase ABC_membrane PF00664.18 EAU92643.2 - 2.2e-41 142.0 24.3 2.1e-21 76.5 4.1 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EAU92643.2 - 8.1e-36 123.3 0.0 1.7e-17 64.0 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EAU92643.2 - 2.9e-09 37.3 0.5 0.052 13.4 0.1 3.5 2 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EAU92643.2 - 7.6e-09 35.2 0.0 0.00042 19.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EAU92643.2 - 3.9e-07 29.5 0.3 0.25 10.5 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EAU92643.2 - 1.1e-06 28.7 1.2 0.0058 16.6 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EAU92643.2 - 7.8e-06 25.3 0.2 0.19 11.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU92643.2 - 9.3e-06 26.1 0.1 0.0037 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EAU92643.2 - 9.9e-06 24.6 0.0 0.038 12.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 EAU92643.2 - 6.6e-05 22.6 0.2 0.056 13.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EAU92643.2 - 0.00012 22.5 0.0 0.61 10.5 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EAU92643.2 - 0.00016 21.2 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 EAU92643.2 - 0.00034 19.3 0.1 0.0022 16.6 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.18 EAU92643.2 - 0.00035 20.5 0.2 0.27 11.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EAU92643.2 - 0.00055 20.7 0.0 1.9 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EAU92643.2 - 0.00085 18.5 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EAU92643.2 - 0.0026 17.1 0.0 1.5 8.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF87 PF01935.12 EAU92643.2 - 0.0034 17.2 1.2 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 EAU92643.2 - 0.0042 16.8 0.0 0.78 9.5 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EAU92643.2 - 0.0043 17.2 0.0 0.3 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EAU92643.2 - 0.0052 16.5 0.8 6.4 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EAU92643.2 - 0.0053 17.0 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EAU92643.2 - 0.012 15.0 1.3 2.8 7.2 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain Dynamin_N PF00350.18 EAU92643.2 - 0.016 15.0 0.3 3.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DEAD PF00270.24 EAU92643.2 - 0.02 14.3 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Pox_A32 PF04665.7 EAU92643.2 - 0.027 13.7 0.5 4.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.7 EAU92643.2 - 0.028 13.4 0.0 2.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EAU92643.2 - 0.03 14.1 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EAU92643.2 - 0.039 13.4 0.0 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 EAU92643.2 - 0.097 12.3 1.4 0.9 9.1 0.1 2.3 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 EAU92643.2 - 0.13 11.9 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EAU92643.2 - 0.14 11.6 0.7 4.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EAU92643.2 - 0.15 11.4 1.1 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EAU92643.2 - 0.2 11.1 0.3 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RRM_1 PF00076.17 EAU92644.2 - 9.4e-15 54.0 0.1 1.3e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU92644.2 - 7.5e-11 41.8 0.0 1.1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU92644.2 - 4.8e-09 35.9 0.2 6.8e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EAU92644.2 - 6.9e-08 32.0 2.0 1.2e-07 31.3 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EAU92644.2 - 0.00098 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EAU92644.2 - 0.0016 18.0 0.1 0.0027 17.3 0.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EAU92644.2 - 0.0039 16.6 2.3 0.011 15.2 1.6 1.8 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger RNA_bind PF08675.6 EAU92644.2 - 0.0089 15.9 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.6 EAU92644.2 - 0.046 13.5 0.1 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA binding motif Glyco_transf_28 PF03033.15 EAU92646.2 - 1e-26 93.3 0.0 2.5e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EAU92646.2 - 5.5e-16 57.8 2.2 5e-10 38.7 0.1 3.5 3 0 0 3 3 3 3 GRAM domain PH PF00169.24 EAU92646.2 - 1.1e-12 48.0 1.4 4.4e-11 42.8 0.4 3.5 4 0 0 4 4 4 1 PH domain PH_6 PF15406.1 EAU92646.2 - 1.6e-06 28.1 0.0 3.4e-05 23.8 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 EAU92646.2 - 1.5e-05 23.7 0.1 3.6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 EAU92646.2 - 8e-05 22.8 1.7 0.0029 17.8 1.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EAU92646.2 - 0.0049 16.9 0.2 0.014 15.3 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain 2OG-FeII_Oxy PF03171.15 EAU92647.2 - 0.00068 19.8 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EAU92647.2 - 0.028 14.9 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal DUF2135 PF09906.4 EAU92647.2 - 0.086 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) MMR_HSR1 PF01926.18 EAU92651.2 - 3.8e-18 65.5 0.1 6.3e-18 64.8 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU92651.2 - 3.2e-11 42.7 0.0 6.8e-11 41.6 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EAU92651.2 - 0.00019 21.9 0.1 0.0013 19.2 0.0 2.2 1 1 1 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EAU92651.2 - 0.0041 16.9 0.1 0.19 11.5 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MCM PF00493.18 EAU92651.2 - 0.015 14.1 0.1 0.033 13.0 0.0 1.5 2 0 0 2 2 2 0 MCM2/3/5 family ArgK PF03308.11 EAU92651.2 - 0.026 13.3 0.1 0.06 12.1 0.0 1.7 2 0 0 2 2 2 0 ArgK protein Nucleoplasmin PF03066.10 EAU92654.2 - 0.28 10.7 2.2 0.49 9.8 1.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EAU92654.2 - 0.34 10.5 3.2 0.53 9.8 2.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region B-block_TFIIIC PF04182.7 EAU92655.2 - 6.4e-11 41.9 0.8 2.9e-07 30.2 0.0 3.4 4 0 0 4 4 4 2 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EAU92655.2 - 0.0012 18.2 0.2 0.35 10.3 0.0 4.1 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_27 PF13463.1 EAU92655.2 - 0.0033 17.6 0.3 0.043 14.1 0.0 3.2 3 0 0 3 3 3 1 Winged helix DNA-binding domain HTH_20 PF12840.2 EAU92655.2 - 0.02 14.6 0.1 1.4 8.7 0.0 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain Atg14 PF10186.4 EAU92655.2 - 0.59 9.0 6.3 1.6 7.6 4.4 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nucleo_P87 PF07267.6 EAU92655.2 - 1.3 7.5 3.0 3 6.4 2.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PRELI PF04707.9 EAU92656.1 - 1.5e-37 128.5 0.1 1.8e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF2071 PF09844.4 EAU92656.1 - 0.028 13.8 0.6 0.036 13.4 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) ABC_membrane_2 PF06472.10 EAU92657.2 - 3.5e-86 288.8 0.6 4.7e-86 288.4 0.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EAU92657.2 - 1.8e-16 60.6 0.0 3.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EAU92657.2 - 0.00034 20.6 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EAU92657.2 - 0.025 14.1 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU92657.2 - 0.036 14.3 0.0 0.036 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain SMC_N PF02463.14 EAU92657.2 - 0.038 13.2 0.0 0.096 11.9 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EAU92657.2 - 0.043 13.7 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EAU92657.2 - 0.081 13.1 0.2 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EAU92657.2 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 EAU92657.2 - 0.13 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF4258 PF14076.1 EAU92657.2 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Adeno_IVa2 PF02456.10 EAU92657.2 - 0.18 10.4 0.1 0.42 9.1 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein NT5C PF06941.7 EAU92658.2 - 1e-12 47.9 0.1 8.9e-12 44.9 0.1 2.2 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 EAU92658.2 - 8.5e-07 29.3 0.0 2.4e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EAU92658.2 - 0.00024 20.8 0.0 0.00074 19.2 0.0 1.8 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.2 EAU92658.2 - 0.0029 17.8 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU92658.2 - 0.018 15.4 0.0 0.047 14.0 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EAU92658.2 - 0.038 13.8 0.0 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pro_CA PF00484.14 EAU92659.1 - 7.6e-15 55.2 0.1 6.1e-13 49.0 0.0 2.0 1 1 1 2 2 2 2 Carbonic anhydrase RINT1_TIP1 PF04437.8 EAU92660.2 - 2.7e-83 280.1 0.0 6.8e-83 278.8 0.0 1.7 1 1 0 1 1 1 1 RINT-1 / TIP-1 family TRCF PF03461.10 EAU92660.2 - 0.079 12.9 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 TRCF domain DASH_Dad3 PF08656.5 EAU92660.2 - 8 6.2 8.6 28 4.4 1.3 3.6 2 1 2 4 4 4 0 DASH complex subunit Dad3 DUF4203 PF13886.1 EAU92662.1 - 1.2e-49 168.6 24.4 1.6e-49 168.2 16.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF2524 PF10732.4 EAU92664.1 - 0.057 13.5 0.4 0.078 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) PPR_2 PF13041.1 EAU92665.1 - 1.2e-36 124.3 0.0 8.8e-09 35.2 0.0 8.9 5 3 5 10 10 10 7 PPR repeat family PPR_3 PF13812.1 EAU92665.1 - 2.5e-21 74.0 15.3 6.1e-05 22.9 0.0 12.3 14 0 0 14 14 14 4 Pentatricopeptide repeat domain PPR PF01535.15 EAU92665.1 - 3.2e-20 70.6 8.5 0.014 15.3 0.0 11.4 13 0 0 13 13 13 5 PPR repeat PPR_1 PF12854.2 EAU92665.1 - 6.3e-12 44.7 4.8 0.42 10.1 0.0 7.8 9 0 0 9 9 9 5 PPR repeat Pro_isomerase PF00160.16 EAU92666.2 - 2.2e-43 148.1 0.0 3.6e-43 147.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EAU92666.2 - 0.00016 20.9 0.0 0.0004 19.6 0.0 1.6 1 0 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EAU92666.2 - 0.0087 15.9 0.3 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 U-box domain Snf7 PF03357.16 EAU92667.2 - 1.6e-21 76.4 4.7 1.8e-21 76.2 3.2 1.0 1 0 0 1 1 1 1 Snf7 PIG-S PF10510.4 EAU92667.2 - 0.13 10.9 1.4 0.14 10.7 1.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein PP2C PF00481.16 EAU92668.2 - 9.2e-36 123.5 0.0 1.8e-33 116.0 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C G_glu_transpept PF01019.16 EAU92669.2 - 7.1e-141 470.1 0.0 1.1e-140 469.5 0.0 1.3 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase Prefoldin_2 PF01920.15 EAU92670.1 - 3.6e-24 84.5 9.3 4.7e-24 84.1 6.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EAU92670.1 - 0.0013 18.4 2.5 0.0021 17.8 1.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit Glyco_hydro_10 PF00331.15 EAU92670.1 - 0.05 12.6 0.0 0.056 12.4 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 10 IncA PF04156.9 EAU92670.1 - 0.086 12.4 13.8 0.19 11.3 9.6 1.5 1 1 0 1 1 1 0 IncA protein FliD_C PF07195.7 EAU92670.1 - 0.14 11.4 4.3 0.18 11.0 3.0 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Tropomyosin_1 PF12718.2 EAU92670.1 - 0.18 11.6 12.4 0.46 10.3 1.4 2.2 2 0 0 2 2 2 0 Tropomyosin like APG6 PF04111.7 EAU92670.1 - 0.27 10.2 11.8 0.93 8.4 8.2 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4201 PF13870.1 EAU92670.1 - 0.3 10.5 6.7 0.65 9.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3166 PF11365.3 EAU92670.1 - 0.42 11.0 4.8 0.82 10.1 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) End3 PF12761.2 EAU92670.1 - 0.48 10.0 6.6 0.75 9.4 4.5 1.3 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TSC22 PF01166.13 EAU92670.1 - 0.51 10.3 4.0 4.6 7.2 0.1 2.7 2 1 1 3 3 3 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 EAU92670.1 - 0.52 10.1 12.6 1.6 8.5 2.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macoilin PF09726.4 EAU92670.1 - 0.58 8.3 7.6 0.66 8.1 5.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 EAU92670.1 - 0.76 8.6 9.6 0.036 13.0 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.7 EAU92670.1 - 1.8 8.8 9.2 0.57 10.4 3.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 EAU92670.1 - 2.1 8.8 9.2 2.6 8.5 1.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Occludin_ELL PF07303.8 EAU92670.1 - 2.8 8.7 6.4 5 7.9 0.5 2.1 1 1 0 2 2 2 0 Occludin homology domain TPR_MLP1_2 PF07926.7 EAU92670.1 - 2.9 7.6 14.2 2.3 7.9 3.2 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.6 EAU92670.1 - 4 7.4 10.6 6 6.9 1.7 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF972 PF06156.8 EAU92670.1 - 4.9 7.5 9.3 14 6.0 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ADIP PF11559.3 EAU92670.1 - 5 7.0 11.9 0.37 10.6 2.4 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EAU92670.1 - 5.6 6.0 12.6 4.8 6.3 2.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.1 EAU92670.1 - 5.8 7.2 10.4 1.7 9.0 1.8 2.3 2 1 0 2 2 2 0 Snapin/Pallidin COG2 PF06148.6 EAU92670.1 - 5.9 6.7 6.9 22 4.8 3.8 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YgaB PF14182.1 EAU92670.1 - 6.1 7.1 10.6 0.58 10.4 2.4 2.6 2 2 0 2 2 2 0 YgaB-like protein THOC7 PF05615.8 EAU92670.1 - 6.8 6.9 11.4 8.2 6.6 1.0 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 FlxA PF14282.1 EAU92670.1 - 6.9 6.6 18.5 0.62 10.0 6.8 2.2 2 0 0 2 2 2 0 FlxA-like protein AAA_13 PF13166.1 EAU92670.1 - 7.6 4.8 13.5 3.1 6.1 3.3 2.0 1 1 0 2 2 2 0 AAA domain Striatin PF08232.7 EAU92670.1 - 7.9 6.8 9.9 0.65 10.3 1.6 2.1 1 1 0 2 2 2 0 Striatin family TBPIP PF07106.8 EAU92670.1 - 8 5.9 12.9 3.9 6.9 2.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 EAU92670.1 - 8.5 6.1 10.4 8.5 6.1 1.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4404 PF14357.1 EAU92670.1 - 9.6 6.7 7.8 1.1 9.7 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) MFS_1 PF07690.11 EAU92671.2 - 1.7e-38 132.2 34.4 1.7e-38 132.2 23.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU92671.2 - 4.1e-12 45.4 3.8 4.1e-12 45.4 2.7 2.0 2 1 0 3 3 3 1 Sugar (and other) transporter Ribosomal_S17 PF00366.15 EAU92671.2 - 5.8e-12 45.4 0.8 5.8e-12 45.4 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 TRI12 PF06609.8 EAU92671.2 - 3.8e-09 35.2 0.4 3.8e-09 35.2 0.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FPN1 PF06963.7 EAU92671.2 - 0.007 14.8 0.0 0.012 14.0 0.0 1.3 1 0 0 1 1 1 1 Ferroportin1 (FPN1) WD40 PF00400.27 EAU92672.2 - 3.9e-07 29.6 17.8 0.00057 19.6 0.1 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Transglut_N PF00868.15 EAU92672.2 - 0.031 14.3 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family IKI3 PF04762.7 EAU92672.2 - 0.23 9.2 0.1 11 3.6 0.0 2.4 3 0 0 3 3 3 0 IKI3 family Peptidase_M41 PF01434.13 EAU92673.1 - 1.4e-73 246.9 0.0 1.9e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EAU92673.1 - 2.8e-42 144.0 0.0 6.4e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EAU92673.1 - 5.1e-09 36.2 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 EAU92673.1 - 0.0022 18.1 0.1 0.093 12.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU92673.1 - 0.0038 16.9 0.5 0.012 15.3 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EAU92673.1 - 0.0044 16.7 0.8 0.16 11.6 0.0 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EAU92673.1 - 0.0046 15.7 0.0 0.0081 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 EAU92673.1 - 0.0047 16.3 0.1 0.014 14.8 0.1 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EAU92673.1 - 0.0081 16.9 0.0 0.028 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EAU92673.1 - 0.017 14.5 0.0 0.057 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EAU92673.1 - 0.023 13.8 0.5 0.059 12.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_2 PF07724.9 EAU92673.1 - 0.023 14.6 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EAU92673.1 - 0.034 13.1 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EAU92673.1 - 0.05 13.5 3.4 0.11 12.4 0.1 2.9 2 1 1 3 3 3 0 AAA ATPase domain FUSC PF04632.7 EAU92673.1 - 0.19 10.0 0.8 5.3 5.3 0.2 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF4551 PF15087.1 EAU92673.1 - 9.8 4.4 9.4 15 3.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MFS_1 PF07690.11 EAU92674.2 - 3.1e-31 108.3 43.9 7.2e-26 90.7 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UreD PF01774.12 EAU92675.1 - 2.5e-53 180.6 0.1 3e-53 180.3 0.1 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Me-amine-dh_L PF02975.9 EAU92675.1 - 0.032 14.1 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain NRDE-2 PF08424.5 EAU92677.2 - 3.9e-55 186.9 0.8 3.9e-55 186.9 0.6 2.2 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 EAU92677.2 - 2.3e-06 28.1 1.8 0.0083 16.7 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat MIP-T3 PF10243.4 EAU92677.2 - 0.0001 20.9 12.8 0.00016 20.2 8.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF2731 PF10806.3 EAU92677.2 - 0.21 11.8 0.0 0.87 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2731) TPR_14 PF13428.1 EAU92677.2 - 0.36 11.5 19.2 2.2 9.1 0.0 8.1 7 3 3 10 10 10 0 Tetratricopeptide repeat UPF0113 PF03657.8 EAU92678.1 - 9.1e-10 38.4 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EAU92678.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.8 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis Sec39 PF08314.6 EAU92679.1 - 2.6e-65 220.7 0.0 4.8e-65 219.8 0.0 1.4 1 1 0 1 1 1 1 Secretory pathway protein Sec39 DUF4611 PF15387.1 EAU92679.1 - 0.18 11.9 1.1 0.55 10.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AIP3 PF03915.8 EAU92680.2 - 0.03 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 ERM PF00769.14 EAU92680.2 - 0.16 11.5 2.6 0.28 10.6 1.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TTKRSYEDQ PF10212.4 EAU92680.2 - 0.27 10.1 0.2 0.41 9.5 0.2 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Golgin_A5 PF09787.4 EAU92680.2 - 5.1 5.4 8.3 0.36 9.3 0.1 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Cgr1 PF03879.9 EAU92681.1 - 2.9e-20 72.4 19.6 3.2e-20 72.3 13.6 1.0 1 0 0 1 1 1 1 Cgr1 family PBP_sp32 PF07222.7 EAU92681.1 - 1.1 8.4 5.2 1.1 8.3 3.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 APG6 PF04111.7 EAU92681.1 - 6.9 5.6 8.6 8 5.4 6.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Pep3_Vps18 PF05131.9 EAU92682.2 - 2.1e-38 131.0 0.0 5e-38 129.8 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EAU92682.2 - 1.9e-08 34.0 8.2 0.0018 17.8 0.1 3.7 3 2 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 EAU92682.2 - 8.7e-05 22.6 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 EAU92682.2 - 0.0025 17.6 4.7 0.0039 16.9 1.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EAU92682.2 - 0.0045 16.6 3.1 0.0052 16.4 0.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain TPR_16 PF13432.1 EAU92682.2 - 0.027 15.1 6.1 0.12 13.0 4.3 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1664 PF07889.7 EAU92682.2 - 0.027 14.2 0.9 0.24 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GAD-like PF08887.6 EAU92682.2 - 0.17 11.9 0.4 28 4.8 0.0 2.7 3 0 0 3 3 3 0 GAD-like domain TPR_1 PF00515.23 EAU92682.2 - 0.37 10.4 9.7 3.8 7.2 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EAU92682.2 - 0.6 9.8 1.8 11 5.7 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Clathrin_H_link PF13838.1 EAU92682.2 - 1.7 8.5 4.9 5.5 6.9 0.2 2.7 1 1 1 2 2 2 0 Clathrin-H-link TPR_11 PF13414.1 EAU92682.2 - 4.3 7.0 8.3 25 4.6 1.6 3.2 2 1 1 3 3 3 0 TPR repeat GAS PF13851.1 EAU92683.2 - 0.00046 19.4 21.4 0.00046 19.4 14.9 7.4 1 1 5 7 7 7 3 Growth-arrest specific micro-tubule binding Filament PF00038.16 EAU92683.2 - 0.00061 19.3 123.9 0.34 10.3 19.8 6.0 1 1 3 5 5 5 3 Intermediate filament protein IncA PF04156.9 EAU92683.2 - 0.23 11.0 144.9 0.26 10.8 13.4 7.3 1 1 6 7 7 7 0 IncA protein WEMBL PF05701.6 EAU92683.2 - 0.86 7.9 163.5 0.011 14.2 26.7 4.4 1 1 3 4 4 4 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 EAU92683.2 - 0.97 6.6 138.2 0.23 8.7 36.7 3.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Mito_carr PF00153.22 EAU92684.1 - 3.4e-28 97.1 6.8 6.5e-13 48.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.7 EAU92685.1 - 8e-13 47.8 2.4 1.3e-12 47.1 1.7 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family SDF PF00375.13 EAU92685.1 - 0.00093 18.0 2.4 0.0015 17.3 1.6 1.3 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4229 PF14012.1 EAU92685.1 - 0.057 13.3 0.5 0.25 11.2 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) LCCL PF03815.14 EAU92688.1 - 5.3e-12 45.5 0.0 9.8e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.9 EAU92690.1 - 1.4e-17 63.9 0.1 1.2e-15 57.5 0.1 2.1 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) SH3BGR PF04908.10 EAU92691.2 - 1.1e-12 47.7 0.1 3.7e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein DDHD PF02862.12 EAU92691.2 - 0.57 9.9 2.3 0.99 9.1 1.6 1.3 1 0 0 1 1 1 0 DDHD domain LMWPc PF01451.16 EAU92692.1 - 3.7e-34 117.9 0.0 4.2e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase PTS_IIB PF02302.12 EAU92692.1 - 0.046 14.2 0.1 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIB subunit Aldedh PF00171.17 EAU92693.2 - 1.7e-129 432.1 0.0 2e-129 431.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EAU92693.2 - 0.0012 17.6 0.0 0.0018 17.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Rap1-DNA-bind PF09197.5 EAU92694.2 - 0.027 15.0 10.0 0.63 10.6 2.2 2.9 3 0 0 3 3 3 0 Rap1, DNA-binding RE_MjaI PF09568.5 EAU92694.2 - 5.5 6.4 9.4 2.2 7.7 1.3 2.7 3 0 0 3 3 3 0 MjaI restriction endonuclease GDI PF00996.13 EAU92695.2 - 1e-210 699.6 0.1 1.2e-210 699.4 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rav1p_C PF12234.3 EAU92696.1 - 1.3e-180 601.7 0.0 1.9e-180 601.1 0.0 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Fasciclin PF02469.17 EAU92697.2 - 7.7e-70 232.8 0.0 5.8e-17 61.8 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.22 EAU92697.2 - 9e-69 227.2 5.6 1.4e-23 82.4 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein CTDII PF01556.13 EAU92697.2 - 0.036 13.9 0.1 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 DnaJ C terminal domain DUF619 PF04768.8 EAU92698.1 - 1e-36 125.9 0.0 2.1e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF619) F-box-like PF12937.2 EAU92699.2 - 2.5e-07 30.2 0.6 6.2e-07 29.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92699.2 - 9.3e-07 28.3 1.0 2.7e-06 26.8 0.7 1.8 1 0 0 1 1 1 1 F-box domain UQ_con PF00179.21 EAU92700.2 - 7.5e-13 48.1 0.0 3.7e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme SURF1 PF02104.10 EAU92700.2 - 0.049 13.4 0.0 0.15 11.8 0.0 1.8 1 1 0 1 1 1 0 SURF1 family SKN1 PF03935.10 EAU92701.2 - 5.3e-185 615.3 0.4 6.1e-185 615.1 0.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SNAPc_SNAP43 PF09808.4 EAU92702.2 - 7.6e-05 22.4 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ima1_N PF09779.4 EAU92703.1 - 1.6e-16 60.9 1.1 2.5e-16 60.3 0.7 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Plasmodium_Vir PF05795.6 EAU92704.1 - 0.0028 16.9 0.4 0.0056 15.9 0.3 1.5 1 1 0 1 1 1 1 Plasmodium vivax Vir protein Gemini_mov PF01708.11 EAU92704.1 - 0.055 13.0 0.8 0.24 10.9 0.1 2.3 1 1 1 2 2 2 0 Geminivirus putative movement protein SOBP PF15279.1 EAU92704.1 - 0.055 13.8 2.0 0.063 13.6 1.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4366 PF14283.1 EAU92704.1 - 0.12 11.8 2.3 0.86 8.9 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) PgaD PF13994.1 EAU92704.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein Late_protein_L2 PF00513.13 EAU92704.1 - 2.7 6.7 11.7 3.6 6.3 8.1 1.1 1 0 0 1 1 1 0 Late Protein L2 Hepar_II_III PF07940.8 EAU92705.1 - 1.6e-09 37.6 0.6 1.6e-09 37.6 0.4 1.8 2 0 0 2 2 2 1 Heparinase II/III-like protein Homeobox PF00046.24 EAU92707.2 - 4.4e-07 29.4 0.2 8.3e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EAU92707.2 - 0.074 12.7 0.2 0.19 11.4 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain SR-25 PF10500.4 EAU92707.2 - 1.9 7.8 9.8 0.12 11.8 2.5 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sec3_C PF09763.4 EAU92708.2 - 4.8e-165 550.5 3.9 4.8e-165 550.5 2.7 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EAU92708.2 - 1.3e-19 69.7 0.0 5.2e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 EAU92708.2 - 0.00026 19.6 2.2 0.00076 18.1 1.5 1.8 1 0 0 1 1 1 1 Vps52 / Sac2 family WhiA_N PF10298.4 EAU92708.2 - 0.029 14.2 0.3 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain TB2_DP1_HVA22 PF03134.14 EAU92709.2 - 1.3e-25 88.8 7.3 1.9e-25 88.3 5.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family M20_dimer PF07687.9 EAU92709.2 - 0.037 13.7 0.4 0.076 12.7 0.3 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain Zn_clus PF00172.13 EAU92710.2 - 1.8e-07 30.9 10.9 3.3e-07 30.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EAU92710.2 - 2.5e-07 29.8 0.0 5.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1212 PF06738.7 EAU92711.2 - 8.4e-29 100.4 4.7 1.3e-28 99.7 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1212) DUF4574 PF15141.1 EAU92711.2 - 0.0088 15.7 0.0 0.34 10.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4574) Esterase PF00756.15 EAU92713.2 - 2.4e-43 148.3 0.0 2.8e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EAU92713.2 - 0.00025 20.8 0.1 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EAU92713.2 - 0.026 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EAU92713.2 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.4 EAU92713.2 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Ribonucleas_3_3 PF14622.1 EAU92714.2 - 4.2e-12 46.1 0.0 5.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EAU92714.2 - 2.7e-06 27.8 0.1 6.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EAU92714.2 - 2.1e-05 24.9 0.0 5.7e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain SNF2_N PF00176.18 EAU92715.2 - 5.5e-61 205.9 0.0 4.5e-31 107.7 0.0 3.0 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU92715.2 - 1.7e-10 40.5 0.0 3.5e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EAU92715.2 - 0.00036 20.1 5.1 0.00036 20.1 3.5 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Complex1_LYR PF05347.10 EAU92715.2 - 0.011 15.4 0.3 0.032 14.0 0.2 1.8 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EAU92715.2 - 0.086 13.0 0.2 0.24 11.6 0.2 1.8 1 0 0 1 1 1 0 Complex1_LYR-like zf-C3HC4 PF00097.20 EAU92715.2 - 0.51 10.0 10.2 0.99 9.1 6.1 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EAU92715.2 - 2.5 8.1 9.2 5.8 7.0 5.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec8_exocyst PF04048.9 EAU92716.2 - 3.7e-31 107.6 1.2 1e-30 106.2 0.8 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EAU92716.2 - 5.7e-09 35.3 2.5 1.5e-08 33.8 1.8 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EAU92716.2 - 1.2 8.9 6.0 3.8 7.3 0.5 3.8 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2305 PF10230.4 EAU92717.2 - 1.7e-49 168.6 0.0 2e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EAU92717.2 - 5.1e-11 42.8 0.5 6.7e-11 42.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU92717.2 - 6.6e-07 29.1 0.1 1e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU92717.2 - 0.00078 19.0 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.3 EAU92717.2 - 0.00099 18.3 0.0 0.0021 17.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3089) PGAP1 PF07819.8 EAU92717.2 - 0.0016 18.1 0.0 0.0037 16.8 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein DUF1749 PF08538.5 EAU92717.2 - 0.0051 15.7 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_8 PF06259.7 EAU92717.2 - 0.011 15.2 0.2 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Lipase_3 PF01764.20 EAU92717.2 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1694 PF07997.6 EAU92717.2 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) SNF2_N PF00176.18 EAU92718.2 - 7.1e-60 202.3 0.1 1e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU92718.2 - 2.7e-13 49.5 0.0 2.5e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EAU92718.2 - 3.2e-12 45.8 0.9 2e-07 30.1 0.2 2.5 1 1 1 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.1 EAU92718.2 - 4.1e-06 26.2 6.7 2.6e-05 23.5 2.1 2.5 1 1 1 2 2 2 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.19 EAU92718.2 - 0.0019 17.8 10.2 0.014 15.0 0.2 3.4 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EAU92718.2 - 0.18 11.4 12.1 0.26 10.9 0.0 4.2 4 0 0 4 4 4 0 PHD-finger PHD_2 PF13831.1 EAU92718.2 - 2 7.8 5.6 2 7.7 0.1 3.5 3 0 0 3 3 3 0 PHD-finger PGAP1 PF07819.8 EAU92719.1 - 1.6e-07 31.1 0.0 3.6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EAU92719.1 - 0.00019 21.3 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU92719.1 - 0.00068 19.4 0.0 0.002 17.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EAU92719.1 - 0.0023 17.2 0.1 0.0065 15.7 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EAU92719.1 - 0.0034 16.9 0.2 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold LCAT PF02450.10 EAU92719.1 - 0.012 14.5 0.1 0.025 13.5 0.0 1.4 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EAU92719.1 - 0.016 14.3 0.0 0.041 12.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EAU92719.1 - 0.05 13.2 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Kelch_3 PF13415.1 EAU92720.2 - 3.3e-29 100.3 12.3 4.3e-08 33.0 0.0 7.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EAU92720.2 - 7.7e-25 86.4 15.9 1.1e-06 28.3 0.0 7.2 3 2 2 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EAU92720.2 - 1.5e-21 75.5 4.4 5.8e-06 26.2 0.7 6.1 3 2 2 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EAU92720.2 - 3.7e-20 71.4 10.4 0.00029 20.7 0.0 6.5 5 1 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EAU92720.2 - 3.1e-19 68.2 6.2 8.4e-06 25.2 0.0 6.5 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EAU92720.2 - 7.2e-13 47.7 12.3 0.015 15.0 1.4 6.4 5 2 0 5 5 5 4 Kelch motif Reo_sigmaC PF04582.7 EAU92720.2 - 5.5 6.0 23.0 0.046 12.8 0.6 4.3 3 1 1 4 4 4 0 Reovirus sigma C capsid protein S1 PF00575.18 EAU92721.1 - 5.8e-61 202.5 29.5 5e-12 45.7 0.0 10.8 10 1 1 11 11 11 9 S1 RNA binding domain TPR_14 PF13428.1 EAU92721.1 - 3.5e-07 30.2 0.0 0.32 11.7 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EAU92721.1 - 9.3e-05 22.2 0.1 1.3 9.0 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EAU92721.1 - 0.00011 22.7 0.0 2.2 9.0 0.0 4.1 3 1 1 5 5 5 2 Tetratricopeptide repeat EXOSC1 PF10447.4 EAU92721.1 - 0.0003 20.6 9.5 0.91 9.5 1.3 6.2 5 1 0 5 5 5 1 Exosome component EXOSC1/CSL4 TPR_19 PF14559.1 EAU92721.1 - 0.00051 20.3 0.0 5.9 7.3 0.0 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EAU92721.1 - 0.0075 16.3 0.1 0.02 15.0 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_65C PF03633.10 EAU92721.1 - 0.023 14.7 0.0 0.06 13.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain TPR_15 PF13429.1 EAU92721.1 - 0.025 13.6 1.0 0.22 10.5 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EAU92721.1 - 0.028 14.8 0.1 30 5.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU92721.1 - 0.032 14.1 0.3 4.3 7.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat S1_2 PF13509.1 EAU92721.1 - 0.052 13.4 1.2 2.5 8.1 0.0 4.2 5 0 0 5 5 5 0 S1 domain Suf PF05843.9 EAU92721.1 - 0.055 13.1 0.1 0.055 13.1 0.0 4.8 4 1 1 5 5 5 0 Suppressor of forked protein (Suf) TPR_1 PF00515.23 EAU92721.1 - 0.2 11.3 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-met PF12874.2 EAU92722.1 - 1.5e-06 28.1 1.2 2.7e-06 27.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EAU92722.1 - 0.034 13.4 0.6 0.062 12.5 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pal1 PF08316.6 EAU92723.1 - 0.00032 21.1 0.1 0.00032 21.1 0.0 2.6 3 0 0 3 3 3 1 Pal1 cell morphology protein Drc1-Sld2 PF11719.3 EAU92725.1 - 3.4e-15 56.0 11.5 3.4e-15 56.0 8.0 3.2 1 1 1 2 2 2 1 DNA replication and checkpoint protein PCI PF01399.22 EAU92727.1 - 3.9e-20 72.1 0.1 1.8e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain LUC7 PF03194.10 EAU92727.1 - 0.02 14.4 0.4 0.02 14.4 0.3 1.6 2 0 0 2 2 2 0 LUC7 N_terminus MRP-S25 PF13741.1 EAU92728.1 - 3.1e-58 196.9 2.7 7.3e-57 192.4 1.9 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EAU92728.1 - 0.00083 19.2 0.7 0.002 18.0 0.5 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 AMP-binding PF00501.23 EAU92729.2 - 4.2e-82 275.7 0.0 5.5e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU92729.2 - 4.1e-15 56.4 1.1 9e-15 55.3 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pal1 PF08316.6 EAU92736.1 - 0.13 12.6 0.1 0.13 12.6 0.1 4.4 4 1 0 4 4 4 0 Pal1 cell morphology protein GARS_A PF01071.14 EAU92737.2 - 1.7e-79 265.9 0.0 2.7e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EAU92737.2 - 4.8e-33 113.5 0.1 2.7e-32 111.2 0.0 2.4 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EAU92737.2 - 1.1e-30 106.6 0.0 2.2e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EAU92737.2 - 2e-29 101.6 0.4 4.8e-29 100.3 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EAU92737.2 - 6.9e-19 67.8 1.7 1e-17 64.1 0.3 3.0 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EAU92737.2 - 2.9e-08 33.6 0.0 8.7e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EAU92737.2 - 3.3e-06 26.0 0.0 1.1e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EAU92737.2 - 0.00082 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CBM_5_12 PF02839.9 EAU92737.2 - 0.00084 18.8 0.6 0.56 9.8 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate binding domain CPSase_L_D2 PF02786.12 EAU92737.2 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EAU92737.2 - 0.085 12.3 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain UPF0150 PF03681.10 EAU92737.2 - 0.1 12.2 0.8 9.3 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) Ank_2 PF12796.2 EAU92738.2 - 7e-10 39.1 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAU92738.2 - 7.4e-09 34.9 0.0 4.2e-07 29.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EAU92738.2 - 1.1e-07 31.8 0.0 1.9e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU92738.2 - 1.5e-06 27.8 0.0 7.5e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EAU92738.2 - 3.6e-06 27.3 0.0 6.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH PF00642.19 EAU92738.2 - 1.8e-05 24.2 10.7 0.021 14.5 0.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAU92738.2 - 2.4e-05 24.1 17.7 0.00013 21.8 4.8 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type NAD_Gly3P_dh_C PF07479.9 EAU92739.2 - 2.7e-47 160.2 0.3 4e-47 159.6 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EAU92739.2 - 1.6e-33 115.6 0.0 2.9e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EAU92739.2 - 3e-09 36.4 0.0 4.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EAU92739.2 - 0.0007 19.9 0.0 0.0039 17.5 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EAU92739.2 - 0.0033 17.2 0.0 0.0083 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 EAU92739.2 - 0.01 16.2 0.0 0.81 10.1 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EAU92739.2 - 0.011 14.8 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EAU92739.2 - 0.031 14.2 0.0 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 EAU92739.2 - 0.058 13.5 0.0 0.35 10.9 0.0 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EAU92739.2 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Syntaxin PF00804.20 EAU92740.2 - 3.8e-16 59.1 6.0 3.8e-16 59.1 4.1 2.7 3 1 0 3 3 3 1 Syntaxin SNARE PF05739.14 EAU92740.2 - 2.3e-14 52.7 3.4 3.9e-14 52.0 0.4 2.6 2 0 0 2 2 2 1 SNARE domain Sed5p PF11416.3 EAU92740.2 - 4.4e-05 22.8 2.3 0.00011 21.5 1.6 1.7 1 0 0 1 1 1 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 EAU92740.2 - 0.0033 17.2 1.0 0.021 14.6 0.1 2.6 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Cluap1 PF10234.4 EAU92740.2 - 0.0046 16.1 1.9 0.46 9.6 0.6 2.2 2 0 0 2 2 2 2 Clusterin-associated protein-1 FliD_N PF02465.13 EAU92740.2 - 0.035 14.4 4.2 0.38 11.1 0.2 2.9 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ATG16 PF08614.6 EAU92740.2 - 0.037 13.8 5.7 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.7 EAU92740.2 - 0.071 13.4 9.0 1.4 9.3 0.8 3.0 2 2 0 2 2 2 0 SlyX zf-C4H2 PF10146.4 EAU92740.2 - 0.15 12.0 4.2 0.49 10.3 0.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein HrpB7 PF09486.5 EAU92740.2 - 0.51 10.2 8.9 0.46 10.3 1.0 2.9 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.6 EAU92740.2 - 0.53 10.2 4.7 3.3 7.6 0.0 3.8 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EAU92740.2 - 0.54 10.0 12.8 3 7.6 1.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 EAU92740.2 - 0.65 10.4 6.6 0.96 9.8 0.5 2.8 3 1 0 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EAU92740.2 - 1.9 8.8 15.4 0.54 10.5 0.8 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Osmo_CC PF08946.5 EAU92740.2 - 2.1 8.4 8.6 2 8.4 0.8 3.3 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Atg14 PF10186.4 EAU92740.2 - 2.4 7.0 9.9 3.4 6.5 0.3 2.5 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EAU92740.2 - 5.9 7.0 10.1 12 6.0 0.8 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RRM_6 PF14259.1 EAU92741.1 - 3.8e-08 33.1 0.0 6.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EAU92741.1 - 1e-07 31.4 0.0 1.1e-06 28.1 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU92741.1 - 0.077 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAPEG PF01124.13 EAU92743.1 - 2.2e-21 75.8 0.3 2.8e-21 75.4 0.2 1.1 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.13 EAU92744.2 - 1.4e-21 76.4 0.1 2.4e-21 75.7 0.0 1.4 1 1 0 1 1 1 1 MAPEG family COX6C PF02937.10 EAU92744.2 - 0.029 14.2 0.0 0.066 13.1 0.0 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc COX14 PF14880.1 EAU92744.2 - 0.057 13.0 0.9 0.2 11.3 0.6 2.0 1 1 0 1 1 1 0 Cytochrome oxidase c assembly WD40 PF00400.27 EAU92745.1 - 8.8e-26 88.8 8.7 6e-10 38.6 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EAU92745.1 - 3.7e-18 65.1 0.0 8.9e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex MAP1B_neuraxin PF00414.12 EAU92745.1 - 0.031 13.5 0.4 0.078 12.3 0.3 1.7 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat PA28_beta PF02252.13 EAU92746.2 - 1.1e-42 145.0 0.5 1.4e-42 144.6 0.3 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 EAU92746.2 - 0.01 15.9 0.1 0.026 14.6 0.1 1.7 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit zf-C2H2 PF00096.21 EAU92749.2 - 2.9e-08 33.5 20.1 0.00011 22.3 1.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU92749.2 - 9.4e-05 22.5 3.8 9.4e-05 22.5 2.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EAU92749.2 - 0.012 15.7 0.1 0.012 15.7 0.1 2.8 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EAU92749.2 - 0.019 15.0 0.4 0.019 15.0 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding EF-hand_7 PF13499.1 EAU92750.1 - 1.3e-13 50.8 2.2 3.5e-07 30.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EAU92750.1 - 5.2e-12 44.5 1.1 1.4e-05 24.5 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EAU92750.1 - 4.6e-11 41.1 5.5 4.1e-05 22.5 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 EAU92750.1 - 0.00036 19.7 1.3 0.14 11.6 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EAU92750.1 - 0.0056 16.5 0.0 1.6 8.7 0.0 3.1 2 1 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 EAU92750.1 - 0.048 13.6 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.8 EAU92750.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_8 PF13833.1 EAU92750.1 - 0.37 10.4 3.1 12 5.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair adh_short PF00106.20 EAU92751.2 - 3.1e-29 102.0 0.2 7.2e-29 100.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU92751.2 - 9.4e-20 71.4 0.1 1.2e-19 71.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU92751.2 - 1.1e-10 41.4 0.1 1.6e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EAU92751.2 - 3.6e-07 29.6 0.0 1.1e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EAU92751.2 - 1.7e-06 28.1 0.0 3.4e-06 27.1 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EAU92751.2 - 0.00024 20.5 0.1 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.10 EAU92751.2 - 0.014 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 EAU92751.2 - 0.014 14.6 0.0 0.052 12.8 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.12 EAU92751.2 - 0.029 13.2 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.13 EAU92751.2 - 0.046 13.7 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PI-PLC-X PF00388.14 EAU92752.2 - 0.04 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain DUF1586 PF07625.6 EAU92752.2 - 1 9.2 4.7 2.2 8.1 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) DMPK_coil PF08826.5 EAU92753.2 - 0.0017 18.2 1.9 0.0031 17.3 1.3 1.4 1 0 0 1 1 1 1 DMPK coiled coil domain like Spc42p PF11544.3 EAU92753.2 - 0.0056 16.5 0.1 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 Spindle pole body component Spc42p Nnf1 PF03980.9 EAU92753.2 - 0.029 14.3 1.3 0.029 14.3 0.9 1.7 2 0 0 2 2 2 0 Nnf1 Snapin_Pallidin PF14712.1 EAU92753.2 - 0.033 14.5 4.8 0.056 13.7 1.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Paralemmin PF03285.10 EAU92753.2 - 0.054 12.9 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Paralemmin Ribosomal_L29 PF00831.18 EAU92753.2 - 0.058 13.0 0.6 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein bZIP_2 PF07716.10 EAU92753.2 - 0.14 12.0 3.2 0.22 11.3 2.2 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF713 PF05218.9 EAU92753.2 - 0.22 11.2 0.9 8.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF713) DUF2130 PF09903.4 EAU92753.2 - 0.24 10.1 0.8 0.38 9.4 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) HAP1_N PF04849.8 EAU92753.2 - 0.31 9.9 2.4 0.22 10.4 0.7 1.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region bZIP_1 PF00170.16 EAU92753.2 - 0.46 10.4 4.2 0.19 11.7 0.6 1.9 2 0 0 2 2 2 0 bZIP transcription factor TMF_DNA_bd PF12329.3 EAU92753.2 - 0.51 10.1 6.2 0.076 12.8 1.5 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CASP_C PF08172.7 EAU92753.2 - 0.53 9.2 2.4 1.2 8.1 1.7 1.5 1 0 0 1 1 1 0 CASP C terminal TBPIP PF07106.8 EAU92753.2 - 0.64 9.5 3.8 1.2 8.6 0.6 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Herpes_capsid PF06112.6 EAU92753.2 - 0.65 10.0 3.9 1 9.4 2.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Utp11 PF03998.8 EAU92754.2 - 1.3e-58 198.7 25.7 1.9e-58 198.1 17.8 1.3 1 0 0 1 1 1 1 Utp11 protein MerR_2 PF13591.1 EAU92754.2 - 0.083 12.5 0.1 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 MerR HTH family regulatory protein PAT1 PF09770.4 EAU92755.1 - 0.033 12.4 48.7 0.049 11.8 33.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ino80_Iec3 PF14612.1 EAU92755.1 - 0.038 14.0 7.9 0.08 12.9 5.5 1.5 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling BLOC1_2 PF10046.4 EAU92755.1 - 0.33 11.1 7.5 0.74 9.9 5.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mlf1IP PF10248.4 EAU92755.1 - 0.43 10.1 10.8 1 8.9 7.5 1.6 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Adaptin_binding PF10199.4 EAU92755.1 - 0.47 10.7 7.5 1.3 9.2 5.2 1.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3573 PF12097.3 EAU92755.1 - 1 7.8 9.7 1.6 7.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RR_TM4-6 PF06459.7 EAU92755.1 - 1.4 8.7 9.7 2.9 7.7 6.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EAP30 PF04157.11 EAU92755.1 - 1.8 7.6 11.3 3.6 6.6 7.8 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family FAR1 PF03101.10 EAU92755.1 - 3.1 8.3 7.3 0.33 11.5 0.2 2.4 2 0 0 2 2 2 0 FAR1 DNA-binding domain VHS PF00790.14 EAU92756.1 - 4.6e-24 84.6 0.0 1.4e-23 83.1 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EAU92756.1 - 4.2e-06 26.6 2.7 9.6e-06 25.5 1.1 2.1 2 0 0 2 2 2 1 GAT domain tRNA-synt_2b PF00587.20 EAU92757.2 - 4.6e-32 110.9 0.0 8.7e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EAU92757.2 - 1.8e-09 37.5 8.0 1.8e-09 37.5 5.6 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain YPEB PF14620.1 EAU92757.2 - 0.00081 18.5 0.6 0.0012 17.9 0.4 1.2 1 0 0 1 1 1 1 YpeB sporulation CENP-Q PF13094.1 EAU92757.2 - 0.0079 16.2 5.7 0.018 15.0 3.9 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit LMBR1 PF04791.11 EAU92757.2 - 0.031 12.8 0.2 0.039 12.5 0.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2514 PF10721.4 EAU92757.2 - 0.04 13.6 6.2 0.076 12.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) tRNA-synt_2d PF01409.15 EAU92757.2 - 0.042 13.0 0.3 0.26 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) AAA_23 PF13476.1 EAU92757.2 - 0.052 13.8 0.8 0.079 13.2 0.6 1.2 1 0 0 1 1 1 0 AAA domain Glypican PF01153.14 EAU92757.2 - 0.092 11.3 1.0 0.13 10.8 0.7 1.1 1 0 0 1 1 1 0 Glypican bZIP_2 PF07716.10 EAU92757.2 - 0.11 12.3 6.8 0.29 10.9 4.7 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Mnd1 PF03962.10 EAU92757.2 - 0.21 11.2 7.4 0.41 10.2 5.1 1.4 1 0 0 1 1 1 0 Mnd1 family Surfac_D-trimer PF09006.6 EAU92757.2 - 0.47 10.2 8.0 0.13 11.9 2.3 2.6 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation DUF3573 PF12097.3 EAU92757.2 - 0.48 8.9 1.4 0.76 8.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) APG6 PF04111.7 EAU92757.2 - 1.3 8.0 7.2 2 7.3 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 EAU92757.2 - 2.6 8.5 12.5 10 6.6 0.5 2.8 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 EAU92757.2 - 6.1 5.7 10.8 11 4.8 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rep_fac_C PF08542.6 EAU92758.2 - 5.3e-23 80.8 0.0 1.2e-22 79.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EAU92758.2 - 9.7e-13 48.4 0.0 1.7e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EAU92758.2 - 2.3e-12 46.8 0.1 1.3e-10 41.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EAU92758.2 - 6.5e-08 32.5 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EAU92758.2 - 7.7e-07 29.2 0.0 1.8e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EAU92758.2 - 1.1e-06 28.8 0.1 0.0053 16.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EAU92758.2 - 1e-05 24.7 0.1 2.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EAU92758.2 - 1.8e-05 24.3 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EAU92758.2 - 0.00014 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EAU92758.2 - 0.00056 18.7 0.2 0.32 9.6 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 EAU92758.2 - 0.00088 18.4 0.0 0.011 14.9 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EAU92758.2 - 0.0017 18.0 0.1 0.016 14.9 0.0 2.1 1 1 1 2 2 2 1 NTPase AAA_10 PF12846.2 EAU92758.2 - 0.0017 17.8 0.0 0.25 10.7 0.0 2.4 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EAU92758.2 - 0.0033 17.1 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 EAU92758.2 - 0.0047 15.7 0.0 0.014 14.1 0.0 1.7 1 1 1 2 2 2 1 ArgK protein DNA_pol3_delta PF06144.8 EAU92758.2 - 0.015 14.7 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_11 PF13086.1 EAU92758.2 - 0.022 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EAU92758.2 - 0.051 13.7 0.1 0.25 11.5 0.0 2.2 1 1 0 1 1 1 0 RNA helicase FtsK_SpoIIIE PF01580.13 EAU92758.2 - 0.056 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DEAD PF00270.24 EAU92758.2 - 0.063 12.7 0.0 1.3 8.4 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.1 EAU92758.2 - 0.064 13.5 0.0 0.1 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EAU92758.2 - 0.069 12.8 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_31 PF13614.1 EAU92758.2 - 0.11 12.4 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EAU92758.2 - 0.14 12.4 0.1 0.44 10.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DAG1 PF05454.6 EAU92759.1 - 0.033 13.3 1.9 0.045 12.9 0.1 2.0 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Abhydrolase_6 PF12697.2 EAU92760.1 - 0.039 13.8 0.0 0.071 12.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family RRM_1 PF00076.17 EAU92761.2 - 3.1e-11 42.7 0.1 2e-07 30.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU92761.2 - 1.3e-10 40.9 0.0 0.00018 21.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU92761.2 - 9.3e-10 38.3 0.0 0.0001 22.1 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU92761.2 - 0.0088 15.8 0.0 0.62 9.9 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif RNA_pol_Rpb6 PF01192.17 EAU92762.2 - 6.2e-22 77.1 0.2 9.8e-22 76.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Rad51 PF08423.6 EAU92763.2 - 7.2e-108 359.3 0.2 2.6e-106 354.2 0.1 2.3 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EAU92763.2 - 1.7e-10 40.6 0.0 3.5e-10 39.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain HHH_5 PF14520.1 EAU92763.2 - 0.00012 22.1 0.1 0.00026 21.0 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EAU92763.2 - 0.0011 18.5 0.4 0.0067 16.0 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.10 EAU92763.2 - 0.0015 17.9 0.3 0.0029 17.0 0.2 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain AAA PF00004.24 EAU92763.2 - 0.0095 16.1 1.5 0.032 14.4 0.2 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HHH_3 PF12836.2 EAU92763.2 - 0.018 15.0 0.2 0.065 13.1 0.1 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.10 EAU92763.2 - 0.027 13.3 1.3 0.031 13.1 0.1 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.1 EAU92763.2 - 0.09 12.3 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain NIR_SIR_ferr PF03460.12 EAU92763.2 - 0.096 12.3 0.2 2.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain DUF1565 PF07602.6 EAU92763.2 - 0.099 11.7 0.2 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) CWC25 PF12542.3 EAU92764.2 - 4e-26 91.2 1.0 4e-26 91.2 0.7 4.2 4 0 0 4 4 4 2 Pre-mRNA splicing factor Cir_N PF10197.4 EAU92764.2 - 1.1e-12 47.7 15.0 1.1e-12 47.7 10.4 4.0 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Ion_trans PF00520.26 EAU92765.2 - 9.1e-05 21.7 1.3 9.1e-05 21.7 0.9 1.6 2 0 0 2 2 2 1 Ion transport protein ANTH PF07651.11 EAU92767.1 - 2.4e-69 233.1 0.0 2.4e-69 233.1 0.0 3.2 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EAU92767.1 - 9.6e-64 213.9 9.7 9.6e-64 213.9 6.7 5.7 4 3 3 7 7 7 1 I/LWEQ domain ENTH PF01417.15 EAU92767.1 - 2.3e-06 27.4 0.9 2.9e-05 23.9 0.0 3.4 4 0 0 4 4 4 1 ENTH domain TcdB_N PF12918.2 EAU92767.1 - 0.00022 21.2 2.4 0.00064 19.7 0.0 3.1 3 0 0 3 3 3 1 TcdB toxin N-terminal helical domain SURF1 PF02104.10 EAU92768.2 - 5.6e-59 199.5 0.0 6.9e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family GMP_synt_C PF00958.17 EAU92769.2 - 0.11 12.2 0.0 0.4 10.4 0.0 2.0 2 0 0 2 2 2 0 GMP synthase C terminal domain DUF211 PF02680.9 EAU92769.2 - 0.18 11.6 0.1 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 DUF4294 PF14127.1 EAU92769.2 - 0.3 10.6 2.3 0.93 9.0 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) Myb_DNA-binding PF00249.26 EAU92771.2 - 3.1e-10 39.9 0.0 2.5e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EAU92771.2 - 0.00023 21.2 0.1 0.00046 20.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RmlD_sub_bind PF04321.12 EAU92772.2 - 5.6e-11 41.8 0.0 6e-08 31.9 0.0 2.3 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 EAU92772.2 - 5.5e-10 39.5 0.0 7.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EAU92772.2 - 1.1e-09 37.3 0.0 3.9e-05 22.4 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EAU92772.2 - 1.9e-09 37.3 0.0 1.7e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EAU92772.2 - 0.00014 20.8 0.0 0.0016 17.4 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EAU92772.2 - 0.0019 17.2 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF849 PF05853.7 EAU92772.2 - 0.039 12.8 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) TrkA_N PF02254.13 EAU92772.2 - 0.052 13.5 0.0 0.15 12.0 0.0 1.7 1 1 1 2 2 2 0 TrkA-N domain Oxidored_FMN PF00724.15 EAU92773.2 - 7.3e-74 248.7 0.0 9.4e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EAU92773.2 - 0.04 12.7 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Fructosamin_kin PF03881.9 EAU92774.2 - 2.2e-61 207.3 0.0 2.7e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EAU92774.2 - 7.9e-14 51.9 0.0 1.2e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EAU92774.2 - 0.12 10.9 0.0 0.15 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EAU92774.2 - 0.15 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RNA_pol_Rpb2_6 PF00562.23 EAU92775.1 - 1.7e-126 422.0 0.1 2.9e-126 421.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EAU92775.1 - 2.4e-68 229.0 0.0 3.9e-68 228.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EAU92775.1 - 6.2e-48 162.7 0.1 1.3e-47 161.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EAU92775.1 - 9.1e-29 99.5 0.2 2.4e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EAU92775.1 - 1.6e-27 95.1 2.0 2.3e-27 94.5 0.5 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EAU92775.1 - 8.1e-24 83.1 0.1 1.8e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EAU92775.1 - 2.5e-22 78.5 1.6 5.4e-22 77.4 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Lung_7-TM_R PF06814.8 EAU92776.2 - 2.7e-55 187.3 12.2 3.7e-55 186.9 8.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3099 PF11298.3 EAU92776.2 - 0.016 14.9 0.7 0.091 12.5 0.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) PX PF00787.19 EAU92777.1 - 3.9e-19 68.4 0.4 2e-18 66.2 0.3 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EAU92777.1 - 2.2e-09 36.9 6.0 0.0001 21.6 0.0 2.3 1 1 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EAU92777.1 - 3.6e-05 23.3 1.2 0.026 14.0 0.1 3.0 3 0 0 3 3 3 2 BAR domain IncA PF04156.9 EAU92777.1 - 0.19 11.2 1.0 2.2 7.8 0.5 2.2 2 0 0 2 2 2 0 IncA protein NPV_P10 PF05531.7 EAU92777.1 - 0.4 10.9 1.6 7.2 6.9 0.1 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein HORMA PF02301.13 EAU92778.2 - 2.1e-19 69.8 0.2 2.5e-19 69.6 0.1 1.0 1 0 0 1 1 1 1 HORMA domain MTD PF01993.13 EAU92778.2 - 0.037 13.0 0.3 0.049 12.6 0.2 1.1 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase AceK PF06315.6 EAU92778.2 - 0.083 11.1 0.1 0.091 11.0 0.0 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) ABC1 PF03109.11 EAU92779.2 - 1.1e-22 80.2 0.0 6.7e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 EAU92779.2 - 0.094 12.4 0.0 0.27 10.9 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_transf_8 PF01501.15 EAU92780.1 - 2.4e-31 108.9 0.0 3.6e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EAU92780.1 - 0.0039 16.5 0.1 0.0068 15.7 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Zip PF02535.17 EAU92780.1 - 3.2 6.6 8.7 5.7 5.8 6.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3759 PF12585.3 EAU92782.2 - 0.0087 15.9 0.7 0.019 14.8 0.2 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3759) Mating_C PF12737.2 EAU92783.1 - 1.4e-124 416.2 30.0 1.4e-124 416.2 20.8 1.4 2 0 0 2 2 2 1 C-terminal domain of homeodomain 1 Mating_N PF12731.2 EAU92783.1 - 1.5e-21 76.0 0.1 2.7e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox_KN PF05920.6 EAU92783.1 - 4.3e-18 64.7 0.7 4.3e-18 64.7 0.5 3.1 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 EAU92783.1 - 0.0017 17.9 0.0 0.0057 16.2 0.0 1.9 1 0 0 1 1 1 1 Homeobox domain Mating_C PF12737.2 EAU92786.2 - 1.4e-154 514.9 33.3 1.4e-154 514.9 23.1 1.4 2 0 0 2 2 2 1 C-terminal domain of homeodomain 1 Mating_N PF12731.2 EAU92786.2 - 9.8e-31 105.5 1.6 2.9e-30 104.0 1.1 1.8 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox_KN PF05920.6 EAU92786.2 - 3e-18 65.2 1.2 3.6e-17 61.7 0.0 3.1 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 EAU92786.2 - 0.00042 19.8 0.0 0.0018 17.8 0.0 2.2 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 EAU92788.1 - 2.7e-13 49.3 1.6 2.7e-13 49.3 1.1 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EAU92788.1 - 0.00022 20.8 1.2 0.00058 19.5 0.8 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EAU92788.1 - 0.038 13.0 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Taxilin PF09728.4 EAU92788.1 - 0.05 12.6 1.3 0.071 12.1 0.9 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Kinetocho_Slk19 PF12709.2 EAU92788.1 - 0.069 13.2 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Central kinetochore-associated Ail_Lom PF06316.6 EAU92788.1 - 0.18 11.3 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein VPS28 PF03997.7 EAU92788.1 - 0.3 10.6 0.8 0.77 9.3 0.3 1.8 1 1 1 2 2 2 0 VPS28 protein Dzip-like_N PF13815.1 EAU92788.1 - 0.51 10.1 2.2 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Mating_C PF12737.2 EAU92789.1 - 1.1e-100 337.4 40.4 1.1e-100 337.4 28.0 2.1 2 1 1 3 3 3 1 C-terminal domain of homeodomain 1 Mating_N PF12731.2 EAU92789.1 - 9.8e-28 95.8 2.6 2.2e-27 94.7 1.8 1.6 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox_KN PF05920.6 EAU92789.1 - 6e-18 64.2 3.8 1.8e-17 62.7 0.6 2.8 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EAU92789.1 - 0.0025 17.3 0.1 0.0025 17.3 0.1 2.8 3 0 0 3 3 3 1 Homeobox domain Peptidase_M3 PF01432.15 EAU92790.2 - 7.6e-137 457.0 0.0 1.1e-136 456.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF1754 PF08555.5 EAU92792.1 - 2.3e-16 60.1 8.9 2.3e-16 60.1 6.2 1.5 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.1 EAU92792.1 - 0.004 16.2 0.1 0.0061 15.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) PP2C_C PF07830.8 EAU92792.1 - 0.0077 16.3 2.4 0.07 13.2 0.0 2.7 3 0 0 3 3 3 1 Protein serine/threonine phosphatase 2C, C-terminal domain BNIP3 PF06553.7 EAU92792.1 - 0.025 13.9 8.4 0.032 13.6 5.8 1.1 1 0 0 1 1 1 0 BNIP3 FAM60A PF15396.1 EAU92792.1 - 0.054 13.2 6.1 0.06 13.0 4.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Herpes_LP PF03363.8 EAU92792.1 - 0.066 12.7 1.0 0.082 12.4 0.7 1.1 1 0 0 1 1 1 0 Herpesvirus leader protein CTF_NFI PF00859.13 EAU92792.1 - 0.19 11.4 3.0 0.21 11.3 2.1 1.0 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region SR-25 PF10500.4 EAU92792.1 - 0.27 10.6 20.1 0.41 10.0 13.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1751 PF08551.5 EAU92793.2 - 3.9e-25 88.0 5.2 6.7e-25 87.2 3.6 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EAU92793.2 - 0.63 10.0 10.3 2.7 8.0 7.1 2.0 1 1 0 1 1 1 0 Rhomboid family Vps51 PF08700.6 EAU92794.2 - 2.7e-14 52.7 0.3 2.7e-14 52.7 0.2 2.5 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 EAU92794.2 - 0.14 11.8 0.5 1.4 8.6 0.0 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec5 2TM PF13239.1 EAU92795.2 - 0.32 11.0 3.8 17 5.5 0.0 3.4 3 0 0 3 3 3 0 2TM domain Sdh_cyt PF01127.17 EAU92795.2 - 1 9.1 7.4 0.15 11.9 1.9 2.0 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SecE PF00584.15 EAU92796.1 - 3.9e-16 58.3 0.1 4.5e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF2976 PF11190.3 EAU92796.1 - 0.07 12.6 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Mit_proteolip PF08039.6 EAU92796.1 - 0.077 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial proteolipid PPR_3 PF13812.1 EAU92797.2 - 2.9e-07 30.2 0.0 0.004 17.3 0.0 5.3 5 1 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EAU92797.2 - 1.8e-06 27.8 0.1 0.13 12.2 0.0 5.3 6 0 0 6 6 6 1 PPR repeat family PPR PF01535.15 EAU92797.2 - 2.4e-06 27.1 0.2 0.21 11.6 0.0 6.2 8 0 0 8 8 8 1 PPR repeat PPR_1 PF12854.2 EAU92797.2 - 7.4e-05 22.1 0.1 0.009 15.4 0.1 3.2 3 0 0 3 3 3 1 PPR repeat IFN-gamma PF00714.12 EAU92797.2 - 0.098 12.4 0.3 0.7 9.7 0.0 2.3 2 0 0 2 2 2 0 Interferon gamma GDC-P PF02347.11 EAU92798.1 - 4.3e-185 615.4 0.2 1.2e-173 577.7 0.0 2.9 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EAU92798.1 - 5.6e-06 25.7 0.0 1.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EAU92798.1 - 0.00015 20.6 0.4 0.00079 18.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V YccV-like PF08755.6 EAU92800.2 - 3.8e-20 71.6 0.0 7.8e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EAU92800.2 - 1.8e-08 34.0 0.0 4.5e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.2 EAU92800.2 - 0.0072 16.0 1.5 0.023 14.3 1.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU92800.2 - 0.057 13.0 0.5 0.16 11.6 0.4 1.9 1 0 0 1 1 1 0 F-box domain Nop52 PF05997.7 EAU92801.1 - 3.1e-72 242.5 0.0 4.1e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 EAU92801.1 - 0.00015 21.1 0.0 0.00049 19.4 0.0 1.8 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II UQ_con PF00179.21 EAU92802.1 - 3.7e-39 133.3 0.1 4.8e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EAU92802.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EAU92802.1 - 0.063 13.1 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain Podovirus_Gp16 PF05894.7 EAU92802.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 1 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) 2OG-FeII_Oxy PF03171.15 EAU92803.2 - 0.00017 21.8 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EAU92803.2 - 0.009 16.5 0.0 0.026 15.0 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Chorismate_bind PF00425.13 EAU92804.1 - 4.2e-67 226.1 0.0 5.6e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EAU92804.1 - 2.4e-34 118.4 0.0 3.9e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EAU92804.1 - 5.8e-19 68.5 0.0 1.6e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EAU92804.1 - 1.6e-06 27.7 0.2 3.1e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 Proteasom_PSMB PF10508.4 EAU92805.1 - 0.12 10.5 0.1 0.29 9.3 0.1 1.5 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit dCMP_cyt_deam_1 PF00383.17 EAU92806.2 - 7.1e-06 25.6 0.0 1.5e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region RNase_P_pop3 PF08228.6 EAU92807.2 - 1.7e-16 60.4 0.0 1.8e-11 44.1 0.0 2.4 2 1 0 2 2 2 2 RNase P subunit Pop3 DUF605 PF04652.11 EAU92808.2 - 8.1e-87 292.0 0.4 1e-86 291.7 0.3 1.1 1 0 0 1 1 1 1 Vta1 like BsuBI_PstI_RE PF06616.6 EAU92808.2 - 0.16 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus Lipase_GDSL_2 PF13472.1 EAU92810.2 - 8.9e-11 42.2 0.8 1.1e-10 41.8 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EAU92810.2 - 1.6e-10 41.2 0.3 2.8e-10 40.4 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MMR_HSR1 PF01926.18 EAU92811.2 - 3.3e-15 56.0 0.0 3.3e-14 52.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU92811.2 - 5.1e-07 29.0 0.0 1.5e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EAU92811.2 - 0.00028 20.1 0.0 0.00051 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EAU92811.2 - 0.0037 16.7 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EAU92811.2 - 0.0091 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EAU92811.2 - 0.038 13.8 0.1 0.038 13.8 0.1 3.2 3 1 1 4 4 4 0 Dynamin family AIG1 PF04548.11 EAU92811.2 - 0.075 12.1 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 AIG1 family SURF2 PF05477.6 EAU92811.2 - 0.38 9.8 7.6 0.83 8.7 5.3 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop14 PF04147.7 EAU92811.2 - 7.9 4.2 8.6 12 3.6 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 EAU92813.1 - 1.4e-15 56.4 9.3 0.014 15.2 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat F-box-like PF12937.2 EAU92814.1 - 4.1e-09 36.0 1.7 9.6e-08 31.6 0.4 2.5 2 0 0 2 2 2 2 F-box-like PB1 PF00564.19 EAU92815.2 - 5.8e-13 48.3 0.0 1.4e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain TAF1D PF15333.1 EAU92815.2 - 0.0083 15.9 2.8 0.016 14.9 1.9 1.4 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D TMEM247 PF15444.1 EAU92815.2 - 0.3 10.8 0.6 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 DUF4337 PF14235.1 EAU92815.2 - 0.51 10.1 3.6 1.2 8.9 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ApbA_C PF08546.6 EAU92816.1 - 1.5e-37 128.3 0.1 2.4e-37 127.7 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EAU92816.1 - 5.7e-23 81.0 0.0 1.9e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Xol-1_GHMP-like PF09109.5 EAU92816.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like TPT PF03151.11 EAU92818.1 - 6e-07 29.2 9.9 6e-07 29.2 6.9 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EAU92818.1 - 5.1e-05 23.3 28.1 0.0092 16.0 6.9 2.5 2 1 0 2 2 2 2 EamA-like transporter family COPI_assoc PF08507.5 EAU92818.1 - 0.0015 18.1 5.4 0.002 17.8 0.0 3.2 3 1 0 3 3 3 1 COPI associated protein EmrE PF13536.1 EAU92818.1 - 0.013 15.6 10.1 0.013 15.6 7.0 3.5 4 0 0 4 4 4 0 Multidrug resistance efflux transporter UAA PF08449.6 EAU92818.1 - 0.46 9.3 15.3 0.59 9.0 10.6 1.1 1 0 0 1 1 1 0 UAA transporter family AATase PF07247.7 EAU92819.2 - 1.7e-06 26.8 0.0 2.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase RabGAP-TBC PF00566.13 EAU92821.2 - 2.3e-25 89.3 0.0 4.9e-25 88.2 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Spc97_Spc98 PF04130.8 EAU92822.2 - 1.5e-66 224.9 0.1 3e-66 223.8 0.0 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family Pyrophosphatase PF00719.14 EAU92823.1 - 7.6e-55 184.6 0.2 1e-54 184.2 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Nucleoplasmin PF03066.10 EAU92824.2 - 0.00065 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin ANAPC15 PF15243.1 EAU92824.2 - 0.069 13.2 3.6 0.14 12.2 2.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 I-set PF07679.11 EAU92824.2 - 0.082 12.7 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Immunoglobulin I-set domain Sigma70_ner PF04546.8 EAU92824.2 - 0.78 9.3 2.4 1.3 8.5 1.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EAU92824.2 - 2.9 8.2 5.1 2.6 8.3 2.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal dsrm PF00035.20 EAU92825.2 - 1.3e-09 38.4 0.0 3.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EAU92825.2 - 0.0089 15.9 0.0 0.034 14.1 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EAU92825.2 - 0.097 13.1 0.1 6.1 7.3 0.1 2.4 1 1 0 1 1 1 0 Ribonuclease III domain Thioredoxin PF00085.15 EAU92826.2 - 2.2e-21 75.4 0.0 1e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EAU92826.2 - 0.0023 18.0 0.1 5 7.3 0.1 3.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EAU92826.2 - 0.0061 16.7 0.2 0.031 14.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Actino_peptide PF14408.1 EAU92826.2 - 0.13 12.2 0.4 0.25 11.2 0.3 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes AhpC-TSA PF00578.16 EAU92826.2 - 0.15 11.7 0.1 0.55 9.9 0.0 1.9 1 1 1 2 2 2 0 AhpC/TSA family Glyco_transf_22 PF03901.12 EAU92828.2 - 2.1e-77 260.9 12.4 3.9e-77 260.0 8.6 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family F-box PF00646.28 EAU92830.1 - 9.8e-05 21.9 0.1 0.00021 20.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU92830.1 - 0.00048 19.7 0.4 0.0013 18.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like TEA PF01285.13 EAU92830.1 - 0.096 11.8 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 TEA/ATTS domain family adh_short PF00106.20 EAU92831.1 - 2e-28 99.4 0.5 2.5e-28 99.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU92831.1 - 3.5e-28 98.9 0.1 4.2e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU92831.1 - 3.2e-12 46.5 0.1 4.4e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EAU92831.1 - 0.00099 18.8 0.2 0.0023 17.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EAU92831.1 - 0.0054 16.1 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EAU92831.1 - 0.0087 15.2 0.0 0.017 14.2 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RibD_C PF01872.12 EAU92832.1 - 6e-34 117.4 0.0 7.5e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain BTB PF00651.26 EAU92834.1 - 0.026 14.5 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Smac_DIABLO PF09057.5 EAU92834.1 - 0.035 13.2 0.1 0.067 12.2 0.1 1.5 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Peptidase_M22 PF00814.20 EAU92835.2 - 7.8e-82 274.7 0.0 9.1e-82 274.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Radical_SAM PF04055.16 EAU92837.1 - 1.1e-14 54.9 0.0 2.2e-14 53.9 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Cmc1 PF08583.5 EAU92838.2 - 4.1e-13 48.8 1.5 4.6e-13 48.7 1.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EAU92838.2 - 0.2 11.5 2.9 11 6.0 0.1 2.2 2 0 0 2 2 2 0 CHCH domain COX17 PF05051.8 EAU92838.2 - 0.34 10.9 2.3 6.6 6.8 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) PEX11 PF05648.9 EAU92839.1 - 8.7e-54 182.1 0.5 9.8e-54 181.9 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Lyase_1 PF00206.15 EAU92840.2 - 1.1e-119 399.2 0.0 1.4e-119 398.9 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EAU92840.2 - 2.2e-20 72.4 0.0 5e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EAU92840.2 - 0.036 13.8 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain SNF2_N PF00176.18 EAU92841.2 - 1.2e-71 241.0 2.6 2.1e-71 240.1 1.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EAU92841.2 - 1.8e-49 167.3 20.6 5.2e-49 165.8 14.3 1.8 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.26 EAU92841.2 - 7.2e-13 48.1 0.0 2.1e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EAU92841.2 - 1.4e-07 30.6 0.0 3.2e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DKCLD PF08068.7 EAU92842.1 - 3.1e-30 103.8 0.1 1.4e-29 101.7 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EAU92842.1 - 2.4e-21 76.4 9.0 5.1e-20 72.1 0.2 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EAU92842.1 - 6.8e-21 73.7 1.2 1.7e-20 72.5 0.8 1.7 1 0 0 1 1 1 1 PUA domain CDC27 PF09507.5 EAU92842.1 - 0.00019 20.7 28.7 0.00025 20.4 19.9 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Parvo_coat PF00740.13 EAU92842.1 - 5.3 5.8 5.8 7.2 5.4 4.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CAF-1_p150 PF11600.3 EAU92842.1 - 5.4 6.3 52.2 8.2 5.7 36.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_L22e PF01776.12 EAU92843.2 - 6e-47 158.2 0.5 7.3e-47 158.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family HA2 PF04408.18 EAU92844.2 - 2.6e-19 69.1 0.0 6.9e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAU92844.2 - 1e-12 47.7 0.2 2.1e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EAU92844.2 - 3.5e-11 42.9 0.0 7.6e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EAU92844.2 - 2e-08 33.8 0.0 3.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU92844.2 - 2.5e-07 30.8 0.0 9e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EAU92844.2 - 0.021 15.1 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 1 0 ABC transporter T2SE PF00437.15 EAU92844.2 - 0.035 12.9 0.0 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EAU92844.2 - 0.037 13.5 0.1 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EAU92844.2 - 0.063 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EAU92844.2 - 0.077 12.6 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain MHC_I_2 PF14586.1 EAU92844.2 - 0.17 11.4 0.0 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 DUF258 PF03193.11 EAU92844.2 - 0.27 10.4 0.0 0.69 9.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF72 PF01904.13 EAU92845.2 - 0.048 13.3 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF72 Pkinase PF00069.20 EAU92846.2 - 2.3e-66 223.6 0.0 2.8e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92846.2 - 2.5e-26 92.3 0.0 5e-26 91.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU92846.2 - 6.1e-06 25.4 0.0 9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU92846.2 - 0.04 13.6 0.3 0.1 12.3 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family S_100 PF01023.14 EAU92846.2 - 0.052 12.8 0.3 0.22 10.8 0.1 2.1 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain RIO1 PF01163.17 EAU92846.2 - 0.088 12.1 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family IncA PF04156.9 EAU92847.2 - 2.2e-06 27.3 0.7 4.6e-06 26.3 0.5 1.5 1 0 0 1 1 1 1 IncA protein TPR_MLP1_2 PF07926.7 EAU92847.2 - 0.016 14.9 8.3 0.033 13.9 5.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Taxilin PF09728.4 EAU92847.2 - 0.02 13.9 7.6 0.042 12.9 5.3 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF848 PF05852.6 EAU92847.2 - 0.026 14.3 3.0 0.045 13.5 2.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4515 PF14988.1 EAU92847.2 - 0.037 13.7 7.5 0.064 12.9 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Phage_GP20 PF06810.6 EAU92847.2 - 0.047 13.1 5.3 0.086 12.2 3.7 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 SAP PF02037.22 EAU92847.2 - 0.049 13.1 0.5 0.24 10.9 0.3 2.3 1 0 0 1 1 1 0 SAP domain DUF342 PF03961.8 EAU92847.2 - 0.065 11.6 3.7 0.12 10.7 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 EAU92847.2 - 0.13 10.6 4.5 0.1 11.0 1.1 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain RmuC PF02646.11 EAU92847.2 - 0.15 10.8 4.7 0.21 10.3 3.3 1.2 1 0 0 1 1 1 0 RmuC family BLOC1_2 PF10046.4 EAU92847.2 - 0.16 12.1 3.0 0.29 11.2 2.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 EAU92847.2 - 0.2 9.4 0.3 0.31 8.8 0.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EAU92847.2 - 0.25 11.6 1.8 13 6.1 0.4 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EAU92847.2 - 0.27 10.3 8.5 0.45 9.6 5.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pox_A11 PF05061.8 EAU92847.2 - 0.33 9.9 1.1 0.56 9.2 0.8 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein Cauli_AT PF03233.8 EAU92847.2 - 0.37 10.4 2.0 0.5 10.0 0.7 1.6 2 0 0 2 2 1 0 Aphid transmission protein Spc7 PF08317.6 EAU92847.2 - 0.65 8.5 6.4 1.1 7.9 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FlxA PF14282.1 EAU92847.2 - 0.8 9.6 4.7 2.4 8.1 3.3 1.8 1 0 0 1 1 1 0 FlxA-like protein DUF972 PF06156.8 EAU92847.2 - 0.87 9.9 6.1 2.3 8.5 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EAU92847.2 - 1.2 8.6 11.6 6 6.4 3.9 2.4 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.6 EAU92847.2 - 1.5 8.8 4.9 21 5.0 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 EAU92847.2 - 3.6 6.5 6.9 6.4 5.7 4.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 EAU92847.2 - 6.3 6.3 8.8 24 4.4 6.1 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FMN_dh PF01070.13 EAU92848.2 - 8.5e-105 350.4 0.1 1.5e-104 349.6 0.0 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EAU92848.2 - 9.3e-22 76.6 0.1 2.6e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EAU92848.2 - 6.3e-07 28.6 0.0 1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EAU92848.2 - 0.00018 20.5 1.1 0.0018 17.2 0.2 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EAU92848.2 - 0.00053 19.2 0.2 0.0012 18.0 0.0 1.6 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 EAU92848.2 - 0.027 13.5 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG LIM PF00412.17 EAU92849.2 - 1.3e-10 41.1 33.0 2e-06 27.7 4.1 4.9 5 0 0 5 5 5 3 LIM domain EPO_TPO PF00758.13 EAU92849.2 - 0.31 10.6 0.8 0.85 9.2 0.2 1.8 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin DnaJ PF00226.26 EAU92851.1 - 9.9e-22 76.4 2.4 2e-21 75.4 1.7 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EAU92851.1 - 0.051 13.6 1.1 0.08 12.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 EAU92851.1 - 0.55 10.3 2.9 1.1 9.3 2.0 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 EAU92851.1 - 0.98 9.1 5.0 10 5.8 0.1 2.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EAU92851.1 - 2.7 7.5 5.9 11 5.6 4.1 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EAU92851.1 - 3 7.5 5.2 0.93 9.1 1.3 1.9 2 1 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EAU92851.1 - 3.7 7.2 6.2 10 5.8 4.3 1.8 1 1 0 1 1 1 0 Glycine zipper Sin_N PF04801.8 EAU92854.1 - 1.2e-22 80.3 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region AAA_18 PF13238.1 EAU92856.1 - 4.5e-24 85.1 0.0 5.6e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EAU92856.1 - 1.8e-14 54.5 0.0 2.1e-14 54.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EAU92856.1 - 5.4e-06 26.6 0.0 6.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EAU92856.1 - 2.2e-05 24.3 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EAU92856.1 - 4.2e-05 23.5 0.0 5.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EAU92856.1 - 0.00023 21.2 0.0 0.00026 21.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU92856.1 - 0.00054 19.6 0.2 0.00089 18.9 0.2 1.3 1 0 0 1 1 1 1 Part of AAA domain Cytidylate_kin2 PF13189.1 EAU92856.1 - 0.001 19.0 0.0 0.017 14.9 0.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_14 PF13173.1 EAU92856.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 EAU92856.1 - 0.0016 18.3 0.0 0.0047 16.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.5 EAU92856.1 - 0.0016 17.6 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 EAU92856.1 - 0.0051 17.1 0.0 0.0058 16.9 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EAU92856.1 - 0.012 15.6 0.1 0.015 15.2 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain SKI PF01202.17 EAU92856.1 - 0.014 15.3 0.0 0.066 13.0 0.0 1.8 1 1 0 1 1 1 0 Shikimate kinase RNA_helicase PF00910.17 EAU92856.1 - 0.019 15.1 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 RNA helicase Thymidylate_kin PF02223.12 EAU92856.1 - 0.024 13.9 0.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.13 EAU92856.1 - 0.033 13.7 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EAU92856.1 - 0.034 13.5 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EAU92856.1 - 0.036 13.0 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 EAU92856.1 - 0.043 12.6 0.1 0.057 12.1 0.1 1.2 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 EAU92856.1 - 0.049 12.6 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EAU92856.1 - 0.054 13.2 0.4 0.092 12.4 0.2 1.5 1 1 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 EAU92856.1 - 0.054 12.5 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 EAU92856.1 - 0.056 12.9 0.2 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 EAU92856.1 - 0.059 12.9 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.10 EAU92856.1 - 0.066 11.8 0.0 0.072 11.7 0.0 1.0 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Sigma54_activat PF00158.21 EAU92856.1 - 0.067 12.6 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EAU92856.1 - 0.085 12.4 0.5 0.15 11.6 0.1 1.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EAU92856.1 - 0.087 11.9 0.3 0.11 11.5 0.2 1.3 1 1 0 1 1 1 0 KaiC AAA_10 PF12846.2 EAU92856.1 - 0.087 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 EAU92856.1 - 0.12 12.0 0.1 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Cyclin_N PF00134.18 EAU92858.1 - 7.9e-13 48.0 0.1 1.6e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Lant_dehyd_N PF04737.8 EAU92858.1 - 0.06 13.3 0.7 0.51 10.3 0.1 2.5 2 0 0 2 2 2 0 Lantibiotic dehydratase, N terminus FCH PF00611.18 EAU92859.1 - 2.4e-07 30.8 0.3 3.3e-07 30.4 0.2 1.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EAU92860.2 - 3.6e-42 143.5 0.0 6.9e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF1764 PF08576.5 EAU92861.2 - 2.6e-06 28.1 18.4 3.6e-06 27.6 5.6 2.2 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Mitofilin PF09731.4 EAU92861.2 - 0.0036 16.0 2.6 0.0033 16.1 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4661 PF15576.1 EAU92861.2 - 6.1 6.4 8.8 9.6 5.7 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) ARID PF01388.16 EAU92862.2 - 1.6e-10 40.7 0.0 3.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3518 PF12031.3 EAU92862.2 - 0.18 10.5 0.0 0.56 8.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Arrestin_C PF02752.17 EAU92863.1 - 3.7e-05 23.8 0.0 9.9e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EAU92863.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Ras PF00071.17 EAU92864.1 - 4e-55 185.6 0.0 5e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU92864.1 - 3.2e-18 66.3 0.0 4.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU92864.1 - 1.2e-14 53.8 0.0 7.2e-14 51.3 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU92864.1 - 2.6e-08 33.3 0.0 2.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EAU92864.1 - 3.2e-05 23.4 0.0 4.8e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EAU92864.1 - 0.00042 20.2 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase APC_basic PF05956.6 EAU92864.1 - 0.0082 15.3 0.5 0.011 14.8 0.4 1.3 1 0 0 1 1 1 1 APC basic domain TCP PF03634.8 EAU92864.1 - 0.08 13.3 1.1 0.16 12.3 0.8 1.4 1 0 0 1 1 1 0 TCP family transcription factor AAA_16 PF13191.1 EAU92864.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MRI PF15325.1 EAU92864.1 - 0.12 13.3 2.1 0.26 12.2 1.5 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection Rad21_Rec8_N PF04825.8 EAU92865.2 - 2e-24 85.6 0.4 4e-24 84.6 0.1 1.7 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Peptidase_M28 PF04389.12 EAU92866.1 - 8.3e-32 110.3 0.0 1.6e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EAU92866.1 - 2.5e-06 27.1 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EAU92866.1 - 0.0025 16.6 0.0 0.15 10.8 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Alginate_lyase PF05426.7 EAU92867.2 - 3.8e-43 147.8 0.0 6.1e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Alginate lyase AMP-binding PF00501.23 EAU92868.2 - 2.8e-64 217.0 0.0 3.5e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EAU92868.2 - 3.6e-17 63.0 0.1 9.5e-17 61.7 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GYF PF02213.11 EAU92869.2 - 1.6e-14 53.2 0.0 3.1e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 GYF domain FAD-oxidase_C PF02913.14 EAU92870.2 - 1.2e-53 182.0 0.0 1.7e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EAU92870.2 - 6.8e-18 64.4 0.1 2.6e-17 62.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Methyltransf_14 PF08484.6 EAU92870.2 - 0.042 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Myb_DNA-bind_2 PF08914.6 EAU92871.2 - 7.5e-10 38.4 1.8 1.9e-09 37.1 1.2 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EAU92871.2 - 0.011 16.2 3.7 0.21 12.1 1.5 3.1 3 1 0 3 3 3 0 Rap1, DNA-binding Pkinase PF00069.20 EAU92872.2 - 1.6e-62 210.9 0.0 3.3e-62 209.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92872.2 - 4.6e-20 71.7 0.0 4.5e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU92872.2 - 0.00097 18.1 0.0 0.033 13.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DDA1 PF10172.4 EAU92872.2 - 0.11 12.3 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase DUF3717 PF12512.3 EAU92872.2 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) TTL PF03133.10 EAU92873.1 - 7.3e-46 156.4 0.0 1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EAU92873.1 - 9.1e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RhoGAP PF00620.22 EAU92873.1 - 0.065 12.8 0.2 0.31 10.6 0.0 1.9 1 1 0 2 2 2 0 RhoGAP domain DUF2404 PF10296.4 EAU92874.1 - 0.002 18.2 0.0 0.0047 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Abhydrolase_5 PF12695.2 EAU92875.2 - 0.00031 20.5 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family RNA_pol_Rpb8 PF03870.10 EAU92876.1 - 1.4e-42 145.1 0.1 1.6e-42 144.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Porin_OmpG PF09381.5 EAU92876.1 - 0.022 13.8 0.2 0.047 12.7 0.0 1.6 2 0 0 2 2 2 0 Outer membrane protein G (OmpG) Sec7 PF01369.15 EAU92878.2 - 2.2e-36 125.3 0.0 3.6e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EAU92878.2 - 1.3e-11 44.6 0.0 2.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EAU92878.2 - 3.5e-08 33.5 0.0 7.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Pescadillo_N PF06732.6 EAU92879.1 - 4.5e-118 393.5 0.1 4.5e-118 393.5 0.0 2.3 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EAU92879.1 - 1.7e-09 37.7 0.0 3.8e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LSM PF01423.17 EAU92880.1 - 3e-15 55.5 0.3 5.9e-15 54.5 0.2 1.5 1 1 0 1 1 1 1 LSM domain RdRP PF05183.7 EAU92881.1 - 3.5e-155 517.9 0.0 4.5e-155 517.6 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Cyclin_N PF00134.18 EAU92883.1 - 2.4e-39 133.7 1.2 1.2e-38 131.5 0.3 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EAU92883.1 - 2e-11 43.8 0.1 4.3e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.17 EAU92884.2 - 4.1e-13 49.8 0.5 2.1e-12 47.6 0.3 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EAU92884.2 - 0.025 14.3 0.0 0.09 12.5 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding_2 PF13380.1 EAU92884.2 - 0.049 13.7 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain WAC_Acf1_DNA_bd PF10537.4 EAU92885.2 - 3.8e-36 123.3 0.6 1e-35 121.9 0.4 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EAU92885.2 - 3.3e-14 52.4 0.1 1e-13 50.8 0.1 1.9 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.1 EAU92885.2 - 0.00018 21.2 0.1 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM2 PF15613.1 EAU92885.2 - 0.00023 20.9 0.2 0.00077 19.3 0.2 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EAU92885.2 - 0.0014 18.3 0.1 0.0039 16.9 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 DUF948 PF06103.6 EAU92885.2 - 0.046 13.5 0.8 0.72 9.7 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Aa_trans PF01490.13 EAU92886.2 - 6e-48 163.3 10.9 7.7e-48 162.9 7.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EAU92886.2 - 1.8e-06 27.0 9.8 2.6e-06 26.5 6.8 1.2 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family PCI_Csn8 PF10075.4 EAU92887.1 - 5.4e-23 81.3 0.0 9.4e-23 80.5 0.0 1.4 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EAU92887.1 - 2e-21 76.4 0.2 2.7e-21 76.0 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family WD40 PF00400.27 EAU92888.2 - 5.8e-70 228.8 18.4 6.5e-13 48.0 0.1 7.4 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EAU92888.2 - 7e-10 38.9 0.0 0.0003 20.5 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EAU92888.2 - 7.2e-06 24.4 1.3 1.8 6.6 0.1 4.1 1 1 1 4 4 4 4 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EAU92888.2 - 0.00017 20.5 0.0 0.2 10.4 0.0 2.9 2 1 1 3 3 3 2 Coatomer WD associated region Hira PF07569.6 EAU92888.2 - 0.0053 15.9 0.2 3.6 6.7 0.0 3.1 2 1 2 4 4 4 2 TUP1-like enhancer of split Nucleoporin_N PF08801.6 EAU92888.2 - 0.0059 15.3 6.1 0.55 8.9 0.1 4.1 2 2 2 4 4 4 1 Nup133 N terminal like PQQ_2 PF13360.1 EAU92888.2 - 0.006 16.0 0.2 0.64 9.4 0.1 2.8 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.1 EAU92888.2 - 0.0088 16.2 0.2 3.7 7.9 0.0 3.6 2 1 1 3 3 3 1 PQQ-like domain IKI3 PF04762.7 EAU92888.2 - 0.045 11.5 0.0 0.22 9.2 0.0 1.9 2 0 0 2 2 2 0 IKI3 family DUF4221 PF13970.1 EAU92888.2 - 0.059 12.6 0.0 2.9 7.1 0.0 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4221) DUF1513 PF07433.6 EAU92888.2 - 0.06 12.2 0.1 5.2 5.8 0.0 3.2 1 1 0 3 3 3 0 Protein of unknown function (DUF1513) ubiquitin PF00240.18 EAU92889.1 - 9.8e-138 447.7 21.2 5.2e-34 115.4 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EAU92889.1 - 6.7e-78 256.3 20.9 5.8e-19 67.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EAU92889.1 - 1.6e-24 85.9 9.4 0.00017 21.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EAU92889.1 - 2.4e-21 76.0 0.6 0.0014 18.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EAU92889.1 - 3.7e-14 52.5 2.9 0.12 12.3 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EAU92889.1 - 1.1e-13 51.2 1.7 0.15 12.2 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EAU92889.1 - 1.1e-10 41.3 0.0 1.5 8.8 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EAU92889.1 - 2e-07 30.6 4.9 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EAU92889.1 - 8.7e-07 28.2 0.6 1 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 EAU92889.1 - 3.1e-06 27.0 4.8 6.4 6.7 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG ACT_4 PF13291.1 EAU92889.1 - 0.00081 19.6 1.2 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 EAU92889.1 - 0.0014 18.0 0.0 50 3.2 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EAU92889.1 - 0.0033 15.8 13.1 3.9 5.6 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 EAU92889.1 - 0.012 15.6 5.3 65 3.7 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EAU92889.1 - 0.022 14.6 13.9 8.8 6.3 0.2 4.6 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EAU92889.1 - 0.027 14.4 29.1 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EAU92889.1 - 0.045 13.7 7.0 53 3.9 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EAU92889.1 - 1.4 9.0 12.6 86 3.2 0.1 5.8 4 4 0 4 4 4 0 FERM N-terminal domain CDC48_2 PF02933.12 EAU92889.1 - 1.6 8.4 13.0 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 DUF3781 PF12636.2 EAU92889.1 - 2.2 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Fcf1 PF04900.7 EAU92890.2 - 8.1e-27 93.2 0.2 8.1e-27 93.2 0.1 1.6 2 0 0 2 2 2 1 Fcf1 DUF2012 PF09430.5 EAU92891.1 - 9.9e-24 83.5 0.0 1.4e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EAU92891.1 - 0.0044 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.1 EAU92891.1 - 0.025 14.7 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II ComX PF05952.7 EAU92891.1 - 0.056 12.9 0.1 0.81 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacillus competence pheromone ComX DUF4480 PF13715.1 EAU92891.1 - 0.064 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) CAP PF00188.21 EAU92893.1 - 8.7e-18 64.9 0.0 1.3e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.6 EAU92893.1 - 0.39 10.5 33.1 1.1 9.0 23.0 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF605 PF04652.11 EAU92893.1 - 8.9 5.5 32.5 13 5.0 22.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF3112 PF11309.3 EAU92894.2 - 0.022 14.5 0.6 0.03 14.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Xol-1_N PF09108.5 EAU92894.2 - 0.032 13.9 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal ABC2_membrane_4 PF12730.2 EAU92894.2 - 0.04 13.0 1.2 0.15 11.2 1.5 1.3 2 0 0 2 2 2 0 ABC-2 family transporter protein Colicin_V PF02674.11 EAU92894.2 - 0.11 12.3 3.0 0.15 11.8 2.1 1.2 1 0 0 1 1 1 0 Colicin V production protein FAD_binding_6 PF00970.19 EAU92895.1 - 1.4e-30 105.3 0.0 2.1e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EAU92895.1 - 8.8e-27 93.8 0.0 1.3e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EAU92895.1 - 2.2e-05 24.4 0.0 0.00081 19.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EAU92895.1 - 4.4e-05 23.4 0.0 0.00013 21.9 0.0 1.8 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DSPc PF00782.15 EAU92896.1 - 1.3e-19 70.0 0.0 1e-17 63.9 0.0 2.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EAU92896.1 - 0.00042 19.7 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TFIIF_alpha PF05793.7 EAU92896.1 - 5.1 5.3 18.3 0.029 12.7 5.9 1.8 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.1 EAU92896.1 - 5.5 7.3 10.6 20 5.6 7.4 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF846 PF05832.7 EAU92897.2 - 3.1e-54 182.5 8.2 3.8e-54 182.2 5.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Pkinase PF00069.20 EAU92900.2 - 0.17 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain MDFI PF15316.1 EAU92900.2 - 7.8 6.4 5.3 3.3 7.6 1.2 2.0 2 0 0 2 2 2 0 MyoD family inhibitor AA_permease PF00324.16 EAU92901.2 - 2.3e-121 405.4 30.9 2.7e-121 405.2 21.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EAU92901.2 - 3.9e-38 131.1 36.6 4.7e-38 130.8 25.4 1.0 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.15 EAU92902.2 - 5.7e-42 143.6 0.0 9.6e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EAU92902.2 - 5.7e-11 41.7 2.7 0.00017 21.1 0.1 3.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU92902.2 - 9.2e-10 38.1 2.1 0.0001 21.9 0.3 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EAU92902.2 - 0.0018 18.0 4.0 3.9 7.8 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EAU92902.2 - 0.061 13.5 2.5 39 5.0 0.1 4.3 5 0 0 5 5 5 0 Leucine rich repeat PAXNEB PF05625.6 EAU92903.2 - 2.7e-49 167.9 0.0 7.1e-49 166.5 0.0 1.6 1 1 0 1 1 1 1 PAXNEB protein Peptidase_S24 PF00717.18 EAU92904.2 - 3.2e-07 29.8 0.0 4.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EAU92904.2 - 1.6e-06 27.7 0.0 0.00026 20.5 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TPR_11 PF13414.1 EAU92905.2 - 2.5e-08 33.4 7.6 0.00038 20.0 0.3 3.2 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAU92905.2 - 0.00021 20.9 2.2 0.78 9.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU92905.2 - 0.0032 16.9 1.5 0.64 9.7 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EAU92905.2 - 0.005 17.3 2.7 0.1 13.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU92905.2 - 0.0062 16.2 0.2 0.8 9.6 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat EcoRI PF02963.11 EAU92905.2 - 0.033 12.9 0.1 0.05 12.3 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease EcoRI DUF2400 PF09674.5 EAU92905.2 - 0.1 12.2 0.2 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) TPR_16 PF13432.1 EAU92905.2 - 0.24 12.1 2.3 7.4 7.3 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S64 PF08192.6 EAU92905.2 - 0.54 8.5 3.9 0.71 8.1 2.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 tRNA-synt_His PF13393.1 EAU92905.2 - 3 6.8 5.9 1.3 7.9 2.4 1.5 2 0 0 2 2 2 0 Histidyl-tRNA synthetase AlaDh_PNT_N PF05222.10 EAU92906.1 - 2.2e-29 102.1 0.0 3.2e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EAU92906.1 - 1.2e-12 47.7 0.0 2.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Acyltransferase PF01553.16 EAU92909.2 - 5.8e-15 54.8 0.0 9e-15 54.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Abhydrolase_6 PF12697.2 EAU92911.1 - 6.2e-16 58.9 0.1 2.3e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EAU92911.1 - 3.3e-07 30.1 0.1 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU92911.1 - 0.00029 20.4 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SAPS PF04499.10 EAU92912.2 - 8.3 4.9 7.1 11 4.5 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIT PF04212.13 EAU92913.2 - 0.005 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3543 PF12063.3 EAU92913.2 - 0.046 12.9 0.9 0.086 12.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Septin PF00735.13 EAU92914.2 - 2.9e-110 367.7 0.5 4e-110 367.2 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EAU92914.2 - 9.3e-06 25.5 0.0 3.3e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU92914.2 - 0.0011 18.0 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EAU92914.2 - 0.0016 18.2 3.1 0.11 12.3 0.0 3.0 2 1 0 3 3 3 1 Dynamin family DUF258 PF03193.11 EAU92914.2 - 0.0063 15.7 0.3 0.025 13.7 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EAU92914.2 - 0.01 15.3 0.1 0.13 11.6 0.0 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EAU92914.2 - 0.013 16.3 1.8 0.048 14.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EAU92914.2 - 0.021 14.3 0.1 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EAU92914.2 - 0.037 14.5 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EAU92914.2 - 0.045 13.8 0.2 0.42 10.7 0.0 2.5 3 1 0 3 3 3 0 AAA domain IIGP PF05049.8 EAU92914.2 - 0.061 12.1 0.2 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MutS_V PF00488.16 EAU92915.2 - 2.2e-81 272.7 0.0 3.3e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EAU92915.2 - 6e-36 124.1 1.1 9.2e-36 123.5 0.7 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EAU92915.2 - 5e-22 78.0 0.0 1e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EAU92915.2 - 9.4e-13 48.3 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EAU92915.2 - 0.00089 18.7 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EAU92915.2 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EAU92915.2 - 0.13 12.1 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Integrase_DNA PF02920.10 EAU92915.2 - 0.21 10.9 0.0 0.43 10.0 0.0 1.4 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Oxysterol_BP PF01237.13 EAU92917.2 - 3e-107 358.1 0.0 4.5e-107 357.5 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EAU92917.2 - 1.3e-17 63.6 1.5 1.2e-16 60.4 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.1 EAU92917.2 - 0.035 14.3 1.7 0.086 13.0 0.1 2.5 3 1 0 3 3 3 0 Pleckstrin homology domain PH PF00169.24 EAU92917.2 - 0.035 14.2 1.1 0.43 10.7 0.7 2.5 1 1 0 1 1 1 0 PH domain 6PGD PF00393.14 EAU92918.1 - 4.7e-133 442.8 0.0 5.8e-133 442.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EAU92918.1 - 9.2e-52 175.1 0.0 1.3e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EAU92918.1 - 0.00071 19.9 0.2 0.0014 19.0 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EAU92918.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.11 EAU92918.1 - 0.01 15.2 0.1 0.02 14.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EAU92918.1 - 0.12 11.5 0.1 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Asn_synthase PF00733.16 EAU92919.2 - 5.5e-47 160.4 0.0 5.1e-46 157.2 0.0 2.0 1 1 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EAU92919.2 - 0.081 12.1 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Band_7 PF01145.20 EAU92920.1 - 7.8e-25 87.8 2.8 9.8e-25 87.4 0.9 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family RRM_1 PF00076.17 EAU92921.2 - 7e-54 179.3 0.0 7.5e-19 67.1 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EAU92921.2 - 7.6e-42 141.1 0.0 3.5e-13 49.3 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU92921.2 - 1.6e-26 91.9 0.0 1e-08 34.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EAU92921.2 - 0.00018 21.1 0.0 0.33 10.7 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EAU92921.2 - 0.0026 17.6 0.0 3.9 7.4 0.0 2.7 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) ATG16 PF08614.6 EAU92922.1 - 2.8e-42 144.7 24.0 2.8e-42 144.7 16.6 1.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF2828 PF11443.3 EAU92922.1 - 0.032 12.4 6.6 0.039 12.1 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EzrA PF06160.7 EAU92922.1 - 0.29 9.2 17.6 0.16 10.1 10.6 1.7 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 EAU92922.1 - 0.32 11.3 20.7 0.066 13.5 2.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4094 PF13334.1 EAU92922.1 - 0.34 11.3 11.0 2.6 8.4 2.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Snapin_Pallidin PF14712.1 EAU92922.1 - 0.55 10.5 15.6 1 9.7 4.9 2.6 1 1 1 2 2 2 0 Snapin/Pallidin USP8_interact PF08941.5 EAU92922.1 - 0.57 9.4 5.0 0.32 10.2 1.6 1.9 1 1 1 2 2 2 0 USP8 interacting IncA PF04156.9 EAU92922.1 - 0.64 9.5 26.5 3.6 7.1 7.0 2.6 1 1 0 2 2 2 0 IncA protein DUF1664 PF07889.7 EAU92922.1 - 0.75 9.5 9.0 1.8 8.4 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 EAU92922.1 - 1 8.5 23.6 0.98 8.5 12.5 2.6 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlxA PF14282.1 EAU92922.1 - 1.8 8.5 20.0 0.45 10.4 1.7 3.2 2 1 1 3 3 3 0 FlxA-like protein Filament PF00038.16 EAU92922.1 - 1.8 7.9 23.4 21 4.4 16.2 2.4 1 1 0 1 1 1 0 Intermediate filament protein XhlA PF10779.4 EAU92922.1 - 2.5 8.0 10.2 2.6 8.0 2.9 3.3 3 1 0 3 3 3 0 Haemolysin XhlA DUF3573 PF12097.3 EAU92922.1 - 4.3 5.8 7.5 4.6 5.7 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3573) TMF_TATA_bd PF12325.3 EAU92922.1 - 4.8 6.9 25.0 0.4 10.4 8.0 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Ras PF00071.17 EAU92923.1 - 8.6e-58 194.2 0.1 1e-57 194.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU92923.1 - 6.2e-19 68.6 0.1 1.6e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EAU92923.1 - 1.6e-13 50.2 0.0 2.1e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EAU92923.1 - 1.3e-07 30.9 0.0 1.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU92923.1 - 4.4e-07 29.8 0.0 7.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU92923.1 - 1.3e-06 27.9 0.0 2.7e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EAU92923.1 - 0.00045 20.3 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EAU92923.1 - 0.00071 19.1 0.2 0.058 12.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.13 EAU92923.1 - 0.00082 18.4 0.2 0.036 13.0 0.0 2.3 2 1 0 2 2 2 1 Septin DUF258 PF03193.11 EAU92923.1 - 0.0013 17.9 0.1 0.0026 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EAU92923.1 - 0.0022 17.4 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EAU92923.1 - 0.0038 16.6 0.0 0.01 15.2 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EAU92923.1 - 0.0049 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EAU92923.1 - 0.0052 16.0 0.0 0.0088 15.2 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EAU92923.1 - 0.0054 16.4 0.1 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 NTPase Arch_ATPase PF01637.13 EAU92923.1 - 0.0058 16.3 0.1 0.011 15.4 0.0 1.4 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EAU92923.1 - 0.0081 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EAU92923.1 - 0.0092 15.7 0.0 0.04 13.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EAU92923.1 - 0.014 14.8 0.1 0.027 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EAU92923.1 - 0.014 15.4 0.1 0.021 14.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EAU92923.1 - 0.052 13.2 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EAU92923.1 - 0.078 12.8 0.0 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.15 EAU92926.2 - 1.7e-49 167.2 0.1 1.9e-49 167.0 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3232 PF11554.3 EAU92926.2 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) Glucosamine_iso PF01182.15 EAU92927.1 - 2.5e-66 223.1 0.0 3e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PXA PF02194.10 EAU92928.2 - 1.5e-31 109.4 0.0 6.5e-31 107.3 0.0 1.9 2 0 0 2 2 2 1 PXA domain UPF0052 PF01933.13 EAU92930.2 - 1e-48 166.2 0.0 1.3e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Chorismate_synt PF01264.16 EAU92931.1 - 4.9e-132 439.6 0.0 8.5e-132 438.8 0.0 1.3 1 1 0 1 1 1 1 Chorismate synthase SAP30_Sin3_bdg PF13867.1 EAU92932.1 - 0.0032 17.2 0.2 0.0098 15.7 0.0 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Octopine_DH PF02317.12 EAU92932.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain SKG6 PF08693.5 EAU92934.2 - 0.011 15.0 1.6 0.011 15.0 1.1 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ABC_tran PF00005.22 EAU92935.2 - 2.1e-42 144.6 0.1 4.1e-23 82.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EAU92935.2 - 1.2e-21 76.3 3.8 1.2e-21 76.3 2.6 3.4 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 EAU92935.2 - 3.5e-17 63.3 6.4 0.00012 22.1 0.0 5.3 5 1 1 6 6 5 4 AAA domain SMC_N PF02463.14 EAU92935.2 - 2.6e-08 33.3 0.0 0.0048 16.1 0.0 3.9 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EAU92935.2 - 8.1e-07 28.4 0.1 0.01 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EAU92935.2 - 1.3e-06 28.8 0.0 0.053 14.0 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 EAU92935.2 - 1.4e-06 28.3 0.5 0.11 12.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EAU92935.2 - 3e-06 27.0 0.0 0.1 12.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EAU92935.2 - 4.4e-06 26.6 0.1 0.024 14.5 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EAU92935.2 - 4.4e-06 25.9 0.1 0.032 13.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EAU92935.2 - 2.5e-05 25.0 2.9 0.14 12.9 0.0 3.8 4 0 0 4 4 3 2 AAA domain ArgK PF03308.11 EAU92935.2 - 8e-05 21.5 0.2 0.023 13.4 0.0 2.5 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 EAU92935.2 - 0.00026 20.5 3.5 1.4 8.2 0.0 4.2 4 1 0 4 4 4 2 AAA-like domain AAA_16 PF13191.1 EAU92935.2 - 0.00043 20.3 11.5 0.019 14.9 0.3 3.6 3 1 0 3 3 3 2 AAA ATPase domain MobB PF03205.9 EAU92935.2 - 0.00069 19.3 0.1 0.39 10.4 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EAU92935.2 - 0.0014 18.8 6.1 0.19 11.8 0.0 4.2 3 3 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EAU92935.2 - 0.0025 17.6 2.1 0.11 12.3 0.0 3.8 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EAU92935.2 - 0.0027 17.1 0.0 0.98 8.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EAU92935.2 - 0.0033 17.7 2.3 2.6 8.3 0.0 4.3 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.1 EAU92935.2 - 0.0065 16.3 0.1 1.3 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EAU92935.2 - 0.0066 16.6 0.0 3.5 7.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 EAU92935.2 - 0.0078 15.1 0.2 0.39 9.6 0.0 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EAU92935.2 - 0.011 15.5 0.0 11 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EAU92935.2 - 0.013 15.3 4.6 0.56 10.0 0.0 3.5 4 2 0 4 4 3 0 Dynamin family FtsK_SpoIIIE PF01580.13 EAU92935.2 - 0.013 14.9 1.8 0.11 11.8 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 EAU92935.2 - 0.037 13.8 0.1 0.037 13.8 0.1 3.8 4 0 0 4 4 3 0 Domain of unknown function DUF87 AAA PF00004.24 EAU92935.2 - 0.046 13.9 1.0 14 5.8 0.1 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EAU92935.2 - 0.052 13.2 0.0 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 EAU92935.2 - 0.054 12.9 0.0 3.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EAU92935.2 - 0.075 12.4 0.1 15 4.9 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EAU92935.2 - 0.13 12.5 0.0 0.13 12.5 0.0 5.0 5 0 0 5 5 5 0 AAA domain AAA_15 PF13175.1 EAU92935.2 - 0.45 9.4 16.0 1.1 8.2 0.0 4.8 4 2 1 6 6 6 0 AAA ATPase domain DNA_topoisoIV PF00521.15 EAU92936.2 - 4.4e-120 401.3 0.5 1e-119 400.1 0.4 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EAU92936.2 - 5e-36 123.5 2.1 1.2e-35 122.3 1.5 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EAU92936.2 - 5.3e-15 55.2 0.1 5.3e-14 52.0 0.0 2.7 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EAU92936.2 - 2.7e-08 33.4 0.0 6.6e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Y_phosphatase PF00102.22 EAU92937.2 - 1.3e-38 132.6 0.0 2.7e-23 82.5 0.0 4.3 2 1 1 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 EAU92937.2 - 4.4e-08 33.4 0.0 1.6e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EAU92937.2 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EAU92937.2 - 0.017 14.6 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain WW PF00397.21 EAU92938.2 - 0.0013 18.5 0.6 0.0033 17.2 0.4 1.8 1 0 0 1 1 1 1 WW domain Fe-S_biosyn PF01521.15 EAU92939.2 - 5.4e-21 74.6 0.0 7.1e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis BAR PF03114.13 EAU92940.1 - 8e-40 136.7 2.5 1e-39 136.3 1.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EAU92940.1 - 4e-16 58.1 0.1 6.6e-16 57.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EAU92940.1 - 8.2e-16 57.3 0.1 1.4e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EAU92940.1 - 1e-11 44.1 0.0 1.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EAU92940.1 - 0.00024 20.4 2.5 0.00052 19.3 1.7 1.5 1 1 0 1 1 1 1 Vps5 C terminal like DUF1451 PF07295.6 EAU92940.1 - 0.011 15.4 1.2 2.5 7.8 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) FAM92 PF06730.6 EAU92940.1 - 0.04 13.2 3.9 0.055 12.8 2.5 1.4 1 1 0 1 1 1 0 FAM92 protein DUF605 PF04652.11 EAU92940.1 - 1.2 8.4 17.7 1.9 7.7 12.3 1.3 1 0 0 1 1 1 0 Vta1 like SBDS_C PF09377.5 EAU92941.1 - 4.5e-39 132.9 1.3 4.5e-39 132.9 0.9 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EAU92941.1 - 3e-34 116.6 1.9 5.5e-34 115.8 1.3 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EAU92941.1 - 0.035 13.8 0.2 0.13 11.9 0.1 1.9 1 1 1 2 2 2 0 Phage XkdN-like protein Glyco_trans_1_4 PF13692.1 EAU92942.2 - 5.6e-19 68.6 0.0 1.2e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EAU92942.2 - 2.1e-07 31.2 1.7 2.6e-07 30.9 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EAU92942.2 - 0.00024 21.3 0.0 0.00047 20.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EAU92942.2 - 0.00024 20.5 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Nfu_N PF08712.6 EAU92943.2 - 1.8e-30 104.3 0.0 4.6e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EAU92943.2 - 5.4e-23 80.5 0.1 1.1e-22 79.5 0.1 1.6 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 EAU92943.2 - 0.0014 18.4 0.2 0.0027 17.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Copper-fist PF00649.13 EAU92944.2 - 1.6e-19 68.7 1.9 1.6e-19 68.7 1.3 3.0 2 1 0 2 2 2 1 Copper fist DNA binding domain UQ_con PF00179.21 EAU92945.2 - 8.4e-28 96.5 0.0 1e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EAU92945.2 - 1e-05 25.2 0.0 0.00041 20.1 0.0 2.0 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EAU92945.2 - 0.0065 16.3 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EAU92945.2 - 0.037 13.7 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 UEV domain Wzt_C PF14524.1 EAU92945.2 - 0.099 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain Ricin_B_lectin PF00652.17 EAU92946.2 - 1.8e-09 37.6 0.0 0.57 10.2 0.0 4.4 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 EAU92946.2 - 8.4e-05 21.9 2.7 3.4 7.0 0.1 4.4 4 0 0 4 4 4 3 Cytolethal distending toxin A/C family Glyoxalase_3 PF13468.1 EAU92946.2 - 0.0055 16.6 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain CLTH PF10607.4 EAU92947.2 - 7.9e-23 80.7 0.0 1.4e-22 79.9 0.0 1.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EAU92947.2 - 8.1e-16 58.2 0.2 1.4e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EAU92947.2 - 5.8e-05 22.7 0.8 0.0001 21.8 0.0 1.9 2 0 0 2 2 2 1 LisH Lyase_8 PF02278.13 EAU92947.2 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, super-sandwich domain UMP1 PF05348.6 EAU92948.1 - 3.4e-21 75.5 0.1 4.2e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Prp19_bind PF06991.6 EAU92949.2 - 6.8e-63 212.5 35.7 6.8e-63 212.5 24.8 2.4 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain NAD_binding_8 PF13450.1 EAU92949.2 - 2.8e-15 56.0 0.3 1.1e-13 51.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain zf-CCHC PF00098.18 EAU92949.2 - 0.086 12.8 3.5 0.24 11.4 2.4 1.8 1 1 0 1 1 1 0 Zinc knuckle Thi4 PF01946.12 EAU92949.2 - 0.29 10.1 0.0 0.57 9.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF913 PF06025.7 EAU92949.2 - 1.5 7.4 5.6 2.9 6.5 3.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SprT-like PF10263.4 EAU92950.2 - 1e-38 132.4 1.2 1.8e-38 131.6 0.8 1.4 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EAU92950.2 - 0.036 14.0 1.7 0.077 12.9 1.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Mucin PF01456.12 EAU92950.2 - 0.57 9.9 10.1 1.1 9.0 7.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.17 EAU92951.1 - 4.4e-59 200.2 0.0 6.9e-34 117.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Ribosomal_S14 PF00253.16 EAU92952.2 - 1.4e-17 62.7 3.5 1.5e-17 62.7 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PUF PF00806.14 EAU92953.2 - 4.2e-60 195.9 12.4 8e-08 31.3 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EAU92953.2 - 0.033 14.4 0.2 0.3 11.3 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function DUF260 Cullin PF00888.17 EAU92956.1 - 5e-08 31.9 0.0 6.1e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Sen15 PF09631.5 EAU92956.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Sen15 protein HMG_box PF00505.14 EAU92957.2 - 1.3e-13 51.0 2.3 2.6e-13 50.0 1.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EAU92957.2 - 9.3e-06 25.9 0.6 2e-05 24.8 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EAU92957.2 - 0.15 11.8 1.7 0.27 11.0 1.1 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DHO_dh PF01180.16 EAU92958.1 - 6.4e-15 54.8 0.0 1.2e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase TRAPP PF04051.11 EAU92959.2 - 9.4e-40 135.6 0.0 1.1e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BTB PF00651.26 EAU92960.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EAU92961.2 - 3.5e-47 156.6 2.6 2e-09 36.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EAU92961.2 - 6.1e-10 37.8 0.1 0.00084 17.5 0.0 3.5 3 0 0 3 3 3 3 Nucleoporin Nup120/160 APG6 PF04111.7 EAU92961.2 - 1.4 7.8 5.5 2.2 7.2 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CS PF04969.11 EAU92963.1 - 3.3e-08 33.9 0.0 4.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 CS domain PLDc_3 PF13918.1 EAU92963.1 - 0.048 13.0 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 PLD-like domain CBM_19 PF03427.8 EAU92965.2 - 0.0013 18.4 0.9 0.0042 16.8 0.6 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) HAD_2 PF13419.1 EAU92966.2 - 2.6e-20 73.3 0.0 3.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EAU92966.2 - 1.6e-13 51.6 0.0 7.1e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EAU92966.2 - 1.2e-10 40.9 0.0 2.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EAU92966.2 - 4.4e-05 23.7 0.0 5.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EAU92966.2 - 0.006 16.4 0.1 0.083 12.7 0.1 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Romo1 PF10247.4 EAU92967.2 - 2.3e-17 62.9 10.3 2.7e-11 43.4 0.3 2.2 1 1 1 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Dynein_heavy PF03028.10 EAU92970.2 - 8.8e-181 602.5 0.0 2.7e-180 600.9 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EAU92970.2 - 5e-132 440.2 7.9 5e-132 440.2 5.5 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EAU92970.2 - 1.1e-77 260.7 0.0 5.9e-77 258.2 0.0 2.3 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 EAU92970.2 - 1.6e-46 158.4 0.2 2.4e-45 154.6 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 EAU92970.2 - 3.2e-45 153.7 0.1 1.3e-44 151.8 0.1 2.0 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 EAU92970.2 - 9.8e-39 133.0 7.6 1.8e-38 132.2 5.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EAU92970.2 - 5.8e-29 100.5 0.0 7.5e-13 48.3 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EAU92970.2 - 3.6e-20 72.1 0.0 1.6e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 EAU92970.2 - 5.8e-13 49.1 0.4 0.0022 18.2 0.0 5.1 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU92970.2 - 8.4e-13 48.6 0.0 0.027 14.5 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EAU92970.2 - 2.5e-11 43.6 3.3 0.11 12.3 0.0 6.0 6 0 0 6 6 5 3 AAA domain AAA_17 PF13207.1 EAU92970.2 - 5e-09 37.0 0.2 0.14 12.9 0.0 6.1 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.1 EAU92970.2 - 2.6e-08 34.0 5.9 0.14 12.1 0.0 6.3 6 1 1 7 7 5 2 AAA ATPase domain AAA_18 PF13238.1 EAU92970.2 - 2.8e-07 30.8 1.2 0.19 12.0 0.0 5.9 6 0 0 6 6 5 1 AAA domain AAA_19 PF13245.1 EAU92970.2 - 4.5e-07 29.5 0.1 0.88 9.3 0.0 4.9 4 0 0 4 4 4 1 Part of AAA domain T2SE PF00437.15 EAU92970.2 - 1.5e-06 27.3 0.0 0.071 12.0 0.0 3.8 4 0 0 4 4 3 2 Type II/IV secretion system protein AAA_14 PF13173.1 EAU92970.2 - 2e-06 27.7 0.0 0.72 9.7 0.0 5.4 5 0 0 5 5 4 2 AAA domain Mg_chelatase PF01078.16 EAU92970.2 - 3.2e-06 26.4 0.4 0.49 9.5 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EAU92970.2 - 9.2e-06 25.2 0.0 0.93 8.9 0.0 4.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.1 EAU92970.2 - 0.0001 21.7 0.0 0.69 9.4 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EAU92970.2 - 0.00015 21.2 1.1 0.36 10.2 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EAU92970.2 - 0.0022 17.1 0.1 2.3 7.2 0.0 4.2 4 0 0 4 4 4 1 Zeta toxin ABC_tran PF00005.22 EAU92970.2 - 0.0043 17.3 2.6 11 6.3 0.0 4.7 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.1 EAU92970.2 - 0.0043 16.4 0.3 1.8 7.9 0.0 4.2 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 EAU92970.2 - 0.0081 16.3 0.0 21 5.3 0.0 4.4 4 0 0 4 4 4 0 RNA helicase ResIII PF04851.10 EAU92970.2 - 0.013 15.3 1.3 2.8 7.7 0.0 4.1 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit LOH1CR12 PF10158.4 EAU92970.2 - 0.015 15.0 15.2 0.077 12.7 0.3 4.1 4 0 0 4 4 2 0 Tumour suppressor protein Phostensin_N PF13916.1 EAU92970.2 - 0.021 14.8 0.2 0.076 13.0 0.0 2.1 2 0 0 2 2 1 0 PP1-regulatory protein, Phostensin N-terminal PduV-EutP PF10662.4 EAU92970.2 - 0.024 14.1 0.2 7.6 6.0 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EAU92970.2 - 0.028 14.1 0.1 24 4.6 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PLRV_ORF5 PF01690.12 EAU92970.2 - 3 6.8 2.0 6.4 5.7 1.4 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GHMP_kinases_N PF00288.21 EAU92971.1 - 3.8e-12 46.0 0.0 7.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EAU92971.1 - 0.00073 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF3512 PF12024.3 EAU92972.1 - 0.15 11.3 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.11 EAU92973.1 - 2.6e-09 36.6 0.1 4.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MFS_1 PF07690.11 EAU92977.2 - 1.1e-13 50.7 7.0 2.6e-13 49.4 0.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Fapy_DNA_glyco PF01149.19 EAU92978.2 - 3.4e-23 82.2 0.1 5.5e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EAU92978.2 - 1.7e-22 78.9 0.0 3.4e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EAU92978.2 - 0.0049 15.4 0.0 0.012 14.1 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.17 EAU92978.2 - 0.069 13.6 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Amelogenin PF02948.10 EAU92978.2 - 0.1 13.2 0.2 3.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Amelogenin Utp12 PF04003.7 EAU92979.1 - 3e-12 46.4 0.4 1.5e-11 44.1 0.3 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 EAU92979.1 - 0.0081 16.0 5.1 0.86 9.5 0.6 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase PF00069.20 EAU92980.2 - 4.4e-76 255.4 0.3 2.6e-75 252.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU92980.2 - 8.4e-37 126.6 1.0 1.3e-36 126.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU92980.2 - 3.4e-06 26.2 0.0 8e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EAU92980.2 - 0.0066 16.2 1.7 0.08 12.6 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3535 PF12054.3 EAU92980.2 - 0.14 10.7 5.2 0.22 10.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) HEAT_EZ PF13513.1 EAU92980.2 - 0.21 12.1 0.4 0.57 10.7 0.3 1.7 1 0 0 1 1 1 0 HEAT-like repeat Suf PF05843.9 EAU92980.2 - 0.5 10.0 9.5 0.68 9.6 6.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 EAU92980.2 - 1.1 8.1 2.7 1.5 7.7 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF605 PF04652.11 EAU92980.2 - 4.7 6.4 21.0 6.3 6.0 14.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF4557 PF15101.1 EAU92980.2 - 4.8 6.9 12.5 7.5 6.3 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DEAD PF00270.24 EAU92983.1 - 1.6e-36 125.3 0.1 3e-36 124.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU92983.1 - 1.3e-25 89.0 0.0 6.3e-24 83.6 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU92983.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit VWA_3 PF13768.1 EAU92984.1 - 5.4e-20 71.6 0.0 1.2e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EAU92984.1 - 1.6e-16 60.0 0.0 3.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EAU92984.1 - 2.2e-11 44.1 0.0 3.9e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EAU92984.1 - 1.5e-09 37.8 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EAU92984.1 - 0.00045 20.0 0.0 0.0066 16.2 0.0 2.4 3 0 0 3 3 3 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 EAU92984.1 - 0.0034 16.5 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.1 EAU92984.1 - 0.0035 16.7 0.0 0.0073 15.7 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Prenyltrans_2 PF13249.1 EAU92984.1 - 0.034 14.5 0.0 0.74 10.2 0.0 2.5 2 0 0 2 2 2 0 Prenyltransferase-like Mito_carr PF00153.22 EAU92985.2 - 3.2e-58 193.4 0.7 1.8e-20 72.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_43 PF04616.9 EAU92986.2 - 1.3e-16 60.5 2.3 2.1e-16 59.8 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EAU92986.2 - 0.057 13.5 3.6 0.19 11.9 2.5 1.9 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) DRP PF06044.7 EAU92986.2 - 0.18 10.7 0.1 1.7 7.5 0.0 2.0 2 0 0 2 2 2 0 Dam-replacing family DEAD PF00270.24 EAU92987.1 - 1.6e-40 138.3 0.3 3e-40 137.4 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU92987.1 - 3e-24 84.6 0.1 5.6e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU92987.1 - 1.1e-06 28.6 0.5 2.5e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EAU92987.1 - 0.00015 20.6 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EAU92987.1 - 0.03 12.7 0.0 1 7.6 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EAU92987.1 - 0.2 11.7 0.9 0.8 9.8 0.6 1.9 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 EAU92987.1 - 2.5 7.0 6.8 3.7 6.5 0.0 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PolyA_pol PF01743.15 EAU92989.2 - 3.7e-16 59.4 0.1 1.5e-15 57.5 0.0 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EAU92989.2 - 1.6e-05 24.3 0.0 3.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A AGTRAP PF06396.6 EAU92991.2 - 4e-07 29.8 1.8 1e-06 28.5 1.3 1.7 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Pex24p PF06398.6 EAU92995.2 - 3e-10 39.4 4.1 4.6e-10 38.8 2.8 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin UPF0175 PF03683.8 EAU92995.2 - 0.022 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HSCB_C PF07743.8 EAU92996.2 - 1.1e-16 60.9 5.1 1.2e-16 60.9 2.5 1.7 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EAU92996.2 - 3.5e-08 33.0 0.1 5.3e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain Herpes_UL14 PF03580.9 EAU92996.2 - 0.012 15.3 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DZR PF12773.2 EAU92996.2 - 0.023 14.4 0.4 0.042 13.6 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.3 EAU92996.2 - 0.067 13.1 2.8 0.21 11.5 1.9 1.9 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ribbon_3 PF13248.1 EAU92996.2 - 0.29 10.3 4.6 0.51 9.6 3.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Rad50_zn_hook PF04423.9 EAU92996.2 - 1.3 8.5 3.9 0.79 9.2 0.7 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF349 PF03993.7 EAU92996.2 - 2.7 8.2 7.3 4.2 7.6 2.1 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) zinc_ribbon_2 PF13240.1 EAU92996.2 - 3.5 7.2 5.7 6.1 6.4 4.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S24e PF01282.14 EAU92997.2 - 2.7e-34 116.8 0.0 5.2e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e HA2 PF04408.18 EAU92997.2 - 1.9e-18 66.3 0.0 5.4e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EAU92997.2 - 2e-11 43.5 0.0 4.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.20 EAU92997.2 - 1.9e-09 37.9 0.0 2.2e-05 24.9 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.24 EAU92997.2 - 3.1e-06 26.7 0.0 7.6e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EAU92997.2 - 0.00031 20.5 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF4095 PF13338.1 EAU92997.2 - 0.026 14.6 0.0 0.96 9.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) ResIII PF04851.10 EAU92997.2 - 0.072 12.9 0.0 0.66 9.7 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EAU92997.2 - 0.076 13.1 0.1 0.41 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain Actin PF00022.14 EAU92998.2 - 8.6e-116 386.5 0.0 1e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 Actin WLM PF08325.5 EAU93000.2 - 0.28 11.0 3.1 0.5 10.1 2.1 1.5 1 1 0 1 1 1 0 WLM domain DEAD PF00270.24 EAU93002.1 - 2.3e-49 167.1 0.0 1.8e-46 157.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU93002.1 - 1.1e-25 89.3 0.0 3.5e-25 87.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MscS_TM PF12794.2 EAU93002.1 - 2.8 6.4 3.4 5.6 5.4 2.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RasGEF PF00617.14 EAU93003.2 - 7.8e-27 94.2 0.1 1.3e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EAU93003.2 - 3e-11 43.3 0.0 7.6e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EAU93003.2 - 2.8e-06 27.8 0.0 8.8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EAU93003.2 - 1.1e-05 24.9 0.0 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 1 Ras family Arf PF00025.16 EAU93003.2 - 0.004 16.4 0.0 0.0077 15.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family SurE PF01975.12 EAU93004.2 - 3.8e-39 134.0 0.0 5.2e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Ribosomal_L15e PF00827.12 EAU93005.2 - 1.3e-91 305.3 10.8 1.8e-91 304.9 7.5 1.1 1 0 0 1 1 1 1 Ribosomal L15 MFS_1 PF07690.11 EAU93006.2 - 5.4e-12 45.0 11.2 6.6e-12 44.8 7.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MARVEL PF01284.18 EAU93007.1 - 0.0072 16.1 2.1 0.0096 15.7 1.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain ATPase_gene1 PF09527.5 EAU93007.1 - 0.24 11.2 5.1 0.4 10.5 3.5 1.4 1 1 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF4481 PF14800.1 EAU93007.1 - 0.76 8.6 2.5 0.88 8.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) SAD_SRA PF02182.12 EAU93010.2 - 9.4e-47 158.1 0.0 1.5e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain SNARE PF05739.14 EAU93011.1 - 4.2e-08 32.7 1.2 4.2e-08 32.7 0.9 3.0 2 1 0 3 3 3 1 SNARE domain DUF1664 PF07889.7 EAU93011.1 - 0.89 9.3 7.2 2.7 7.7 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) V-SNARE_C PF12352.3 EAU93011.1 - 0.98 9.5 5.7 5.4 7.1 0.7 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Laminin_II PF06009.7 EAU93011.1 - 2.8 7.6 7.9 13 5.5 0.1 3.0 2 1 2 4 4 4 0 Laminin Domain II BLOC1_2 PF10046.4 EAU93011.1 - 3.7 7.7 7.6 1.6 8.9 0.2 3.2 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mpp10 PF04006.7 EAU93012.1 - 2e-108 363.3 53.8 2e-108 363.3 37.3 1.7 2 0 0 2 2 2 1 Mpp10 protein Nexin_C PF08628.7 EAU93012.1 - 0.25 11.4 1.5 0.75 9.9 0.1 2.4 2 0 0 2 2 2 0 Sorting nexin C terminal DUF4064 PF13273.1 EAU93013.1 - 0.63 10.1 9.2 1.3 9.1 1.5 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Lyase_8 PF02278.13 EAU93014.2 - 1.9e-33 115.9 0.0 3.1e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 EAU93014.2 - 6.3e-22 77.8 0.0 9.5e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.12 EAU93014.2 - 6.8e-07 29.2 1.5 1.5e-06 28.1 1.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain dUTPase PF00692.14 EAU93014.2 - 0.038 13.4 0.2 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 dUTPase Ribosomal_L32p PF01783.18 EAU93016.2 - 5.5e-14 52.0 4.7 5.5e-14 52.0 3.3 1.6 1 1 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.1 EAU93016.2 - 0.012 15.2 2.1 0.026 14.2 1.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.5 EAU93016.2 - 0.045 13.6 0.9 1.4 8.9 0.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EAU93016.2 - 0.067 13.0 1.9 0.16 11.7 1.2 1.5 1 1 0 1 1 1 0 Double zinc ribbon GFA PF04828.9 EAU93016.2 - 0.071 13.0 1.8 1.9 8.4 1.3 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_2 PF13923.1 EAU93016.2 - 0.086 12.8 1.1 0.15 12.1 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF164 PF02591.10 EAU93016.2 - 0.087 12.6 0.2 7.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-ribbon_3 PF13248.1 EAU93016.2 - 0.28 10.4 3.1 0.4 9.9 2.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain ETC_C1_NDUFA5 PF04716.9 EAU93017.1 - 1.5e-20 72.4 0.1 2.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region LSM PF01423.17 EAU93018.2 - 5.7e-15 54.6 0.1 8.2e-15 54.1 0.1 1.3 1 0 0 1 1 1 1 LSM domain CCDC66 PF15236.1 EAU93018.2 - 0.049 13.2 0.1 0.063 12.8 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Herpes_ICP4_C PF03585.9 EAU93018.2 - 0.17 10.5 0.0 0.18 10.4 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region PHD PF00628.24 EAU93019.2 - 4.8e-10 38.9 8.2 4.8e-10 38.9 5.7 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EAU93019.2 - 0.3 10.8 5.5 0.73 9.6 3.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HABP4_PAI-RBP1 PF04774.10 EAU93020.1 - 5.4e-07 30.0 8.2 5.4e-07 30.0 5.7 3.1 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.17 EAU93021.1 - 4.3e-23 82.1 0.0 6.1e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.20 EAU93023.2 - 2.3e-44 151.4 0.0 2.6e-41 141.4 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93023.2 - 1.6e-15 56.9 0.0 4.4e-14 52.1 0.0 2.9 2 2 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EAU93023.2 - 0.00037 20.3 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EAU93023.2 - 0.0068 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU93023.2 - 0.0081 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAT1 PF09770.4 EAU93023.2 - 0.032 12.4 3.1 0.045 12.0 2.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.9 EAU93023.2 - 0.24 10.7 4.1 0.35 10.2 2.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 EAU93023.2 - 1.6 7.7 4.3 2.4 7.0 3.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GTP_EFTU PF00009.22 EAU93024.1 - 3.3e-56 189.7 0.0 4.7e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAU93024.1 - 4.7e-37 126.1 0.0 1.3e-36 124.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAU93024.1 - 3.2e-16 59.1 0.9 1.1e-15 57.5 0.6 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAU93024.1 - 0.00089 19.2 0.1 0.0026 17.6 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EAU93024.1 - 0.0012 18.3 0.4 0.0012 18.3 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 EAU93024.1 - 0.055 13.3 0.2 0.79 9.5 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain DLH PF01738.13 EAU93025.2 - 2.5e-15 56.3 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2305 PF10230.4 EAU93025.2 - 0.0012 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Elong_Iki1 PF10483.4 EAU93026.2 - 2.6e-10 40.1 0.0 1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Elongator subunit Iki1 Aminotran_1_2 PF00155.16 EAU93028.2 - 1.8e-85 287.0 0.0 2.1e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.15 EAU93029.1 - 3.8e-78 262.6 0.0 5.8e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EAU93029.1 - 1.6e-07 31.0 0.1 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EAU93029.1 - 0.011 14.9 0.3 1.6 7.8 0.0 2.6 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SPRY PF00622.23 EAU93031.2 - 5.5e-18 65.2 0.0 8.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain CBS PF00571.23 EAU93032.2 - 5.7e-22 77.2 1.4 8.8e-11 41.4 0.1 4.7 4 1 0 4 4 4 4 CBS domain PX PF00787.19 EAU93034.1 - 7.7e-16 57.8 0.0 1.7e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EAU93034.1 - 4.8e-10 38.9 4.5 1.3e-09 37.6 3.1 1.8 1 0 0 1 1 1 1 SNARE domain Laminin_II PF06009.7 EAU93034.1 - 3.7 7.3 6.0 8.4 6.1 1.6 2.2 2 0 0 2 2 2 0 Laminin Domain II Mito_carr PF00153.22 EAU93035.1 - 8.7e-59 195.2 0.1 1e-18 66.8 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein IF4E PF01652.13 EAU93036.1 - 6e-50 168.9 0.0 7.7e-50 168.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pil1 PF13805.1 EAU93037.1 - 4.2e-20 72.0 0.6 8.3e-20 71.0 0.4 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 APG6 PF04111.7 EAU93037.1 - 4.8 6.1 11.5 0.13 11.3 2.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Acetyltransf_7 PF13508.1 EAU93039.2 - 6e-10 39.1 0.2 7.3e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EAU93039.2 - 1.2e-09 38.0 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EAU93039.2 - 0.00012 22.2 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EAU93039.2 - 0.00045 19.9 0.0 0.00069 19.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EAU93039.2 - 0.008 16.0 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EAU93039.2 - 0.011 15.7 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ESSS PF10183.4 EAU93040.1 - 4.3e-28 97.7 0.5 5.9e-28 97.3 0.3 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GCV_H PF01597.14 EAU93041.1 - 2.2e-40 137.1 0.1 2.6e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EAU93041.1 - 2.5e-05 23.9 0.1 3.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EAU93041.1 - 7.5e-05 22.2 0.1 0.00013 21.5 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Peptidase_M23 PF01551.17 EAU93041.1 - 0.086 12.8 0.7 1.6 8.8 0.1 2.4 1 1 1 2 2 2 0 Peptidase family M23 Biotin_lipoyl_2 PF13533.1 EAU93041.1 - 0.16 11.6 0.6 4.4 7.0 0.0 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like GTP_EFTU PF00009.22 EAU93042.2 - 2.7e-59 199.7 0.1 4e-59 199.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EAU93042.2 - 5.3e-26 90.6 0.1 4.3e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EAU93042.2 - 5.3e-16 58.4 1.4 1.4e-15 57.1 1.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EAU93042.2 - 3.6e-05 23.6 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EAU93042.2 - 0.0002 20.8 0.1 0.00048 19.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EAU93042.2 - 0.00085 19.8 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DisA_N PF02457.11 EAU93042.2 - 0.062 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding cobW PF02492.14 EAU93042.2 - 0.064 12.7 0.3 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EAU93042.2 - 0.11 11.9 0.2 8.8 5.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ANTH PF07651.11 EAU93046.2 - 0.073 11.7 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 ANTH domain Cation_efflux PF01545.16 EAU93048.2 - 3e-73 246.3 0.8 4.3e-73 245.8 0.6 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EAU93048.2 - 0.021 13.8 4.1 0.052 12.5 2.9 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter Ipi1_N PF12333.3 EAU93050.2 - 6.1e-13 48.6 0.1 2.6e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Cellulase PF00150.13 EAU93051.1 - 4.5e-23 81.8 4.3 6.4e-23 81.3 3.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 EAU93051.1 - 3.6e-06 26.5 0.8 6e-06 25.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.10 EAU93051.1 - 0.0044 16.2 1.4 0.043 12.9 0.6 2.6 1 1 1 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 EAU93051.1 - 0.0063 16.9 0.0 0.028 14.8 0.0 2.2 1 1 0 1 1 1 1 Sugar-binding cellulase-like E1_DerP2_DerF2 PF02221.10 EAU93053.1 - 4.3e-20 72.3 0.1 5.1e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EAU93053.1 - 0.00012 22.1 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 ML-like domain Tetraspannin PF00335.15 EAU93054.2 - 6.4e-05 22.3 3.7 0.00019 20.7 2.5 1.9 1 1 0 1 1 1 1 Tetraspanin family Zip PF02535.17 EAU93054.2 - 0.00016 20.8 0.0 0.00022 20.3 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2839 PF10999.3 EAU93054.2 - 0.031 14.3 0.0 0.12 12.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Bax1-I PF01027.15 EAU93054.2 - 6.7 6.2 12.6 2.6 7.5 6.6 1.7 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Ribosomal_L17 PF01196.14 EAU93056.1 - 6.8e-35 119.5 0.7 1.9e-34 118.0 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L17 TAF1D PF15333.1 EAU93056.1 - 0.12 12.0 0.1 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D PP-binding PF00550.20 EAU93057.2 - 8.7e-15 54.7 0.2 1e-14 54.4 0.2 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EAU93057.2 - 1.7e-06 27.9 0.1 2.3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EAU93057.2 - 0.033 14.2 0.1 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L50 PF10501.4 EAU93057.2 - 0.1 12.5 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S Ribosomal_L13 PF00572.13 EAU93058.1 - 1.1e-26 93.3 0.0 1.7e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 KH_1 PF00013.24 EAU93059.1 - 9.7e-41 137.2 9.7 4e-15 55.2 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EAU93059.1 - 7e-28 95.7 10.1 1.5e-09 37.3 0.7 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EAU93059.1 - 3.4e-10 39.4 0.1 0.015 14.9 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EAU93059.1 - 2.9e-09 36.3 5.7 0.012 15.2 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EAU93059.1 - 0.00019 21.1 3.5 0.3 10.9 0.0 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EAU93059.1 - 0.00028 20.3 0.4 0.1 12.0 0.0 2.6 3 0 0 3 3 3 2 dUTPase NUFIP1 PF10453.4 EAU93060.1 - 1.2e-16 59.9 0.1 2.3e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Peptidase_M16_C PF05193.16 EAU93061.2 - 7.7e-13 48.5 0.0 5.6e-06 26.1 0.0 3.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EAU93061.2 - 2e-10 40.6 0.1 9e-09 35.2 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF433 PF04255.9 EAU93061.2 - 0.068 12.6 0.2 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Exo_endo_phos PF03372.18 EAU93062.2 - 5.9e-19 68.9 0.0 1.1e-18 68.0 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EAU93062.2 - 0.16 11.5 0.0 10 5.7 0.0 2.5 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase RhoGEF PF00621.15 EAU93063.1 - 3.8e-19 69.2 0.0 5.8e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain IL11 PF07400.6 EAU93064.1 - 0.11 11.9 1.7 0.21 11.1 1.2 1.4 1 0 0 1 1 1 0 Interleukin 11 Gemini_mov PF01708.11 EAU93064.1 - 0.29 10.7 4.4 8.4 6.0 1.5 2.7 2 0 0 2 2 2 0 Geminivirus putative movement protein Gly-zipper_Omp PF13488.1 EAU93064.1 - 0.5 10.0 3.0 1.1 8.9 2.1 1.5 1 1 0 1 1 1 0 Glycine zipper Fungal_trans PF04082.13 EAU93065.2 - 1.7e-10 40.2 0.0 2.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3563 PF12086.3 EAU93065.2 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) UPF0047 PF01894.12 EAU93066.2 - 1.2e-40 137.9 0.1 1.4e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 p450 PF00067.17 EAU93067.2 - 4.9e-51 173.6 0.0 2.5e-50 171.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EAU93068.2 - 8.5e-10 37.9 0.6 1.5e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Ras PF00071.17 EAU93070.2 - 1.5e-54 183.7 0.0 1.7e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU93070.2 - 2.7e-17 63.3 0.0 3.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU93070.2 - 2e-06 27.1 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU93070.2 - 0.002 17.6 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain CDK5_activator PF03261.10 EAU93071.2 - 2.7 7.2 6.7 4.3 6.5 4.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF423 PF04241.10 EAU93072.1 - 0.003 17.4 0.0 0.071 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF423) Spb1_C PF07780.7 EAU93073.1 - 6.6e-69 231.6 29.2 6.6e-69 231.6 20.2 3.7 3 1 2 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.14 EAU93073.1 - 1.1e-53 181.8 0.0 6.5e-53 179.4 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EAU93073.1 - 1.7e-48 164.1 4.4 1.7e-48 164.1 3.1 5.7 4 2 3 7 7 7 1 Domain of unknown function (DUF3381) Miro PF08477.8 EAU93073.1 - 0.17 12.3 0.1 0.17 12.3 0.1 2.4 3 0 0 3 3 3 0 Miro-like protein zf-DHHC PF01529.15 EAU93074.2 - 4.6e-38 130.3 0.2 7.6e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1858 PF08984.6 EAU93074.2 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1858) DZR PF12773.2 EAU93074.2 - 1.7 8.5 9.0 2.9 7.8 6.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon SLS PF14611.1 EAU93075.2 - 5.3e-06 25.9 0.2 1.4e-05 24.6 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator RNase_E_G PF10150.4 EAU93075.2 - 0.22 10.7 1.0 0.41 9.8 0.7 1.4 1 0 0 1 1 1 0 Ribonuclease E/G family PPR_2 PF13041.1 EAU93077.1 - 6.8e-30 102.7 0.0 1.3e-08 34.6 0.0 7.8 7 1 0 7 7 7 5 PPR repeat family PPR_3 PF13812.1 EAU93077.1 - 1.8e-20 71.4 5.5 2e-06 27.6 0.0 8.8 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 EAU93077.1 - 1e-18 65.9 0.8 5.7e-09 35.3 0.0 7.4 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 EAU93077.1 - 1.1e-13 50.4 0.0 7.9e-06 25.2 0.0 6.6 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 EAU93077.1 - 3.8e-05 23.9 4.7 2.6 8.9 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat Clathrin PF00637.15 EAU93077.1 - 0.018 14.6 0.1 0.47 10.0 0.1 2.9 3 0 0 3 3 3 0 Region in Clathrin and VPS B12-binding_2 PF02607.12 EAU93077.1 - 0.084 12.9 0.0 0.84 9.7 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain AAA_25 PF13481.1 EAU93078.1 - 0.0067 15.8 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain TSC22 PF01166.13 EAU93079.2 - 0.18 11.8 15.2 1.8 8.5 0.0 4.3 4 0 0 4 4 4 0 TSC-22/dip/bun family Macoilin PF09726.4 EAU93079.2 - 0.54 8.4 23.9 0.029 12.6 7.2 2.6 3 0 0 3 3 3 0 Transmembrane protein Myosin_tail_1 PF01576.14 EAU93079.2 - 1.7 6.2 30.6 0.0064 14.2 12.9 2.7 3 0 0 3 3 3 0 Myosin tail DUF972 PF06156.8 EAU93079.2 - 2.6 8.4 20.2 14 6.1 0.1 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF972) IncA PF04156.9 EAU93079.2 - 5.2 6.6 32.4 9.4 5.7 0.3 4.0 2 1 0 3 3 3 0 IncA protein DivIC PF04977.10 EAU93079.2 - 9.4 5.8 31.2 3.7 7.0 1.8 6.0 4 1 1 5 5 5 0 Septum formation initiator APG6 PF04111.7 EAU93079.2 - 9.7 5.1 26.3 4.7 6.1 12.9 3.1 3 0 0 3 3 3 0 Autophagy protein Apg6 Nefa_Nip30_N PF10187.4 EAU93082.1 - 1e-25 89.8 16.4 1e-25 89.8 11.3 1.6 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Es2 PF09751.4 EAU93083.1 - 7.5e-81 272.6 10.7 1.2e-80 272.0 7.4 1.3 1 1 0 1 1 1 1 Nuclear protein Es2 Tegument_dsDNA PF12818.2 EAU93083.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein NUDE_C PF04880.8 EAU93084.2 - 8e-09 36.0 9.1 8e-09 36.0 6.3 2.8 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region ERM PF00769.14 EAU93084.2 - 0.049 13.1 33.5 0.038 13.5 12.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.3 EAU93084.2 - 0.13 12.1 33.9 0.027 14.3 3.4 3.6 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EAU93084.2 - 0.29 10.1 35.6 0.051 12.6 9.0 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 Myb_DNA-bind_3 PF12776.2 EAU93084.2 - 0.62 10.7 4.0 0.42 11.2 0.8 2.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain GAS PF13851.1 EAU93084.2 - 1.1 8.4 32.6 1.7 7.8 13.0 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 EAU93084.2 - 1.1 7.5 21.6 0.15 10.4 5.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) HAUS6_N PF14661.1 EAU93084.2 - 5.4 6.2 25.9 3.3 6.9 5.8 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.8 EAU93084.2 - 9 5.2 12.4 11 5.0 0.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein TPR_MLP1_2 PF07926.7 EAU93084.2 - 9.2 6.0 36.0 11 5.7 10.2 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein EXOSC1 PF10447.4 EAU93085.1 - 3.9e-21 74.7 0.0 7.4e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EAU93085.1 - 0.00025 20.2 0.0 0.0007 18.8 0.0 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region 2-oxoacid_dh PF00198.18 EAU93086.1 - 1.5e-82 276.3 0.0 1.9e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EAU93086.1 - 1.8e-20 72.3 0.6 5e-20 70.9 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EAU93086.1 - 1.3e-15 56.7 0.3 3.3e-15 55.4 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EAU93086.1 - 4.4e-05 23.0 1.0 0.21 11.2 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_2 PF12700.2 EAU93086.1 - 0.16 11.1 0.1 2.2 7.3 0.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein DUF3123 PF11321.3 EAU93086.1 - 0.48 10.7 9.1 0.23 11.7 1.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) DUF904 PF06005.7 EAU93087.2 - 6.7e-05 23.0 28.5 0.069 13.4 2.4 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF904) APG6 PF04111.7 EAU93087.2 - 0.00057 19.0 27.1 0.028 13.4 10.6 2.3 2 0 0 2 2 2 2 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EAU93087.2 - 0.17 11.7 33.5 0.28 11.0 4.2 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 EAU93087.2 - 0.2 11.1 40.7 0.028 13.9 4.9 3.7 3 1 1 4 4 4 0 Ezrin/radixin/moesin family DUF3446 PF11928.3 EAU93087.2 - 0.28 11.3 9.7 0.92 9.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF4201 PF13870.1 EAU93087.2 - 0.61 9.5 27.7 2 7.8 1.7 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) Rab5-bind PF09311.6 EAU93087.2 - 0.64 9.8 33.1 0.028 14.3 3.9 2.7 2 1 0 2 2 2 0 Rabaptin-like protein Filament PF00038.16 EAU93087.2 - 0.65 9.3 29.5 0.058 12.8 2.5 3.1 2 1 1 3 3 3 0 Intermediate filament protein DivIC PF04977.10 EAU93087.2 - 1 8.8 31.5 1.3 8.5 3.4 3.7 3 1 0 3 3 3 0 Septum formation initiator Seryl_tRNA_N PF02403.17 EAU93087.2 - 1.3 9.0 28.3 1 9.3 9.3 3.7 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 EAU93087.2 - 1.4 8.6 34.8 5.2 6.8 5.6 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein COG5 PF10392.4 EAU93087.2 - 1.5 8.7 17.4 0.077 12.9 4.0 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 IncA PF04156.9 EAU93087.2 - 1.6 8.3 37.1 1.3 8.5 3.9 3.2 2 1 0 2 2 2 0 IncA protein DUF972 PF06156.8 EAU93087.2 - 2.5 8.5 28.8 3.8 7.8 2.0 4.2 3 1 2 5 5 4 0 Protein of unknown function (DUF972) DUF3584 PF12128.3 EAU93087.2 - 2.7 5.2 32.4 4.5 4.4 22.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.16 EAU93087.2 - 2.9 7.8 24.3 3.4 7.6 2.8 4.0 3 1 0 3 3 3 0 bZIP transcription factor Herpes_capsid PF06112.6 EAU93087.2 - 7.6 6.5 18.1 1.4 8.9 8.3 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ADIP PF11559.3 EAU93087.2 - 8.5 6.2 36.8 1.4 8.7 6.2 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2263 PF10021.4 EAU93088.1 - 1.3e-23 83.5 0.0 1.7e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) DUF2263 PF10021.4 EAU93089.1 - 2.4e-30 105.4 0.0 2.1e-29 102.4 0.0 2.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Ribosomal_S17 PF00366.15 EAU93093.1 - 9.4e-30 102.4 2.1 1.7e-29 101.6 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DNA_ligase_A_M PF01068.16 EAU93094.2 - 3.5e-63 212.6 0.2 5.8e-63 211.9 0.2 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EAU93094.2 - 1.5e-36 125.8 0.4 3.2e-36 124.7 0.3 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EAU93094.2 - 2.3e-26 92.0 0.0 7e-26 90.4 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EAU93094.2 - 0.0045 16.6 0.1 0.97 9.1 0.0 2.6 2 0 0 2 2 2 1 DNA ligase OB-like domain Virulence_fact PF13769.1 EAU93094.2 - 0.036 13.9 0.3 0.18 11.7 0.2 2.2 1 0 0 1 1 1 0 Virulence factor ORC6 PF05460.8 EAU93094.2 - 0.15 11.1 11.1 0.27 10.3 7.7 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Herpes_TAF50 PF03326.8 EAU93094.2 - 0.38 9.6 7.9 0.59 9.0 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) MPC PF03650.8 EAU93095.1 - 4.3e-37 126.6 0.3 5.1e-37 126.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) NUDIX PF00293.23 EAU93097.1 - 3e-29 101.3 0.0 4.1e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Rad21_Rec8_N PF04825.8 EAU93098.2 - 4.7e-17 61.9 0.0 2.3e-16 59.7 0.0 2.0 1 1 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EAU93098.2 - 0.0029 16.7 0.0 0.0063 15.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3292 PF11696.3 EAU93099.2 - 3.2e-06 25.3 0.7 0.016 13.1 0.3 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3292) GRAM PF02893.15 EAU93099.2 - 7.5e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain PRT_C PF08372.5 EAU93099.2 - 0.0038 16.7 0.1 0.0067 15.9 0.1 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal INCENP_ARK-bind PF03941.10 EAU93100.2 - 3.7e-16 58.7 0.4 1.4e-15 56.8 0.3 2.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region PXPV PF12778.2 EAU93100.2 - 0.007 16.0 7.2 0.007 16.0 5.0 3.0 4 0 0 4 4 4 1 PXPV repeat (3 copies) DCP2 PF05026.8 EAU93101.2 - 1.4e-34 117.8 1.2 2.5e-34 117.0 0.9 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EAU93101.2 - 2.4e-12 46.6 0.0 5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Pribosyltran_N PF13793.1 EAU93102.2 - 5.3e-45 151.8 0.5 3.5e-43 146.0 0.0 2.6 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EAU93102.2 - 3.7e-40 137.6 2.3 3.7e-34 118.0 0.3 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EAU93102.2 - 1.1e-11 44.5 0.7 4.6e-11 42.5 0.3 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EAU93102.2 - 0.0088 15.2 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RdRP PF05183.7 EAU93102.2 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Pkinase PF00069.20 EAU93103.2 - 1.5e-55 188.1 0.0 3.9e-55 186.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93103.2 - 4.9e-24 84.7 0.0 1.1e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CHCC PF10276.4 EAU93104.2 - 4.5e-17 61.5 1.4 6.5e-17 61.1 1.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain AAA_2 PF07724.9 EAU93105.1 - 1.3e-51 174.9 0.0 6e-47 159.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EAU93105.1 - 6e-26 91.1 0.0 2.2e-13 50.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EAU93105.1 - 1.2e-22 79.5 0.1 5.9e-22 77.3 0.1 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EAU93105.1 - 9.4e-20 70.2 3.6 1.2e-12 47.5 0.4 4.3 4 0 0 4 4 4 3 Clp amino terminal domain AAA_5 PF07728.9 EAU93105.1 - 3.9e-15 55.8 0.0 2.8e-08 33.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EAU93105.1 - 7.6e-12 45.5 0.8 0.00012 22.1 0.0 4.3 4 1 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 EAU93105.1 - 1.9e-09 37.7 0.0 0.0056 16.8 0.0 3.8 2 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EAU93105.1 - 3.4e-09 36.3 0.0 4.6e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EAU93105.1 - 4.7e-08 32.6 0.0 0.00045 19.6 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EAU93105.1 - 5.1e-07 29.0 0.0 0.0013 17.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EAU93105.1 - 6.4e-06 26.4 2.2 0.0028 17.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 EAU93105.1 - 9.2e-06 24.6 3.1 0.14 10.8 0.0 3.9 3 1 1 4 4 4 2 TIP49 C-terminus AAA_19 PF13245.1 EAU93105.1 - 2.4e-05 24.0 0.1 0.1 12.3 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 EAU93105.1 - 3.4e-05 23.0 0.5 0.0073 15.4 0.0 3.2 3 1 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EAU93105.1 - 9.9e-05 22.4 0.0 0.55 10.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.1 EAU93105.1 - 0.00012 21.7 0.0 0.023 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EAU93105.1 - 0.00032 19.8 0.4 0.35 9.8 0.0 3.3 4 0 0 4 4 3 1 Holliday junction DNA helicase ruvB N-terminus Laminin_II PF06009.7 EAU93105.1 - 0.00032 20.4 2.2 0.00088 19.0 1.5 1.7 1 0 0 1 1 1 1 Laminin Domain II NACHT PF05729.7 EAU93105.1 - 0.00043 19.9 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 EAU93105.1 - 0.00049 20.9 12.4 1 10.2 3.8 4.5 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EAU93105.1 - 0.001 18.9 0.0 0.34 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EAU93105.1 - 0.0012 18.2 3.1 9.4 5.5 0.0 4.2 3 1 1 4 4 4 0 AAA domain PhoH PF02562.11 EAU93105.1 - 0.002 17.4 0.0 0.51 9.5 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EAU93105.1 - 0.0057 15.5 0.0 0.072 11.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.6 EAU93105.1 - 0.0059 16.2 0.0 31 4.1 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EAU93105.1 - 0.0059 16.4 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 1 Torsin AAA_23 PF13476.1 EAU93105.1 - 0.013 15.8 10.7 7.6 6.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EAU93105.1 - 0.017 15.0 1.4 2.2 8.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.10 EAU93105.1 - 0.021 13.7 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ResIII PF04851.10 EAU93105.1 - 0.022 14.6 0.0 2.3 8.0 0.0 3.0 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit MobB PF03205.9 EAU93105.1 - 0.062 12.9 0.0 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EAU93105.1 - 0.066 12.3 2.0 2.3 7.2 0.0 3.8 4 1 0 4 4 4 0 KaiC AAA_29 PF13555.1 EAU93105.1 - 0.067 12.7 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EAU93105.1 - 0.086 12.4 0.0 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IncA PF04156.9 EAU93105.1 - 0.087 12.4 11.5 0.24 10.9 8.0 1.7 1 0 0 1 1 1 0 IncA protein AAA_10 PF12846.2 EAU93105.1 - 0.12 11.8 0.9 12 5.2 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain ABC_tran PF00005.22 EAU93105.1 - 0.13 12.5 1.9 12 6.2 0.0 3.4 3 0 0 3 3 3 0 ABC transporter Arch_ATPase PF01637.13 EAU93105.1 - 0.2 11.3 6.3 2 8.0 0.0 4.3 4 1 0 4 4 3 0 Archaeal ATPase EMP24_GP25L PF01105.19 EAU93106.2 - 0.0009 18.9 11.1 0.13 11.9 1.0 3.1 2 1 1 3 3 3 2 emp24/gp25L/p24 family/GOLD CCDC155 PF14662.1 EAU93106.2 - 0.00096 18.7 9.4 0.00096 18.7 6.5 2.1 2 1 1 3 3 3 1 Coiled-coil region of CCDC155 IncA PF04156.9 EAU93106.2 - 0.0088 15.6 16.4 4.8 6.7 10.5 2.7 2 1 0 2 2 2 1 IncA protein DUF3584 PF12128.3 EAU93106.2 - 0.0094 13.3 15.6 0.015 12.6 10.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) DUF4201 PF13870.1 EAU93106.2 - 0.011 15.2 11.3 0.011 15.2 7.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) AAA_13 PF13166.1 EAU93106.2 - 0.026 12.9 7.5 0.037 12.5 5.2 1.2 1 0 0 1 1 1 0 AAA domain Tox-GHH PF15636.1 EAU93106.2 - 0.034 13.7 2.2 0.1 12.2 1.5 1.8 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Transposase_22 PF02994.9 EAU93106.2 - 0.04 12.3 8.6 0.031 12.7 5.0 1.4 2 0 0 2 2 2 0 L1 transposable element V_ATPase_I PF01496.14 EAU93106.2 - 0.048 11.5 5.0 0.073 10.9 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EAU93106.2 - 0.057 13.5 9.5 0.075 13.1 4.3 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family US2 PF02476.10 EAU93106.2 - 0.12 12.8 1.8 0.77 10.2 0.6 2.4 3 0 0 3 3 3 0 US2 family DALR_2 PF09190.6 EAU93106.2 - 0.16 12.2 0.6 11 6.3 0.1 3.4 3 0 0 3 3 3 0 DALR domain NPV_P10 PF05531.7 EAU93106.2 - 0.24 11.6 2.8 11 6.3 0.4 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EAU93106.2 - 0.37 9.9 19.8 0.5 9.5 9.7 2.4 2 1 1 3 3 2 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.8 EAU93106.2 - 0.82 8.6 8.0 0.055 12.5 2.2 1.5 2 0 0 2 2 2 0 TMPIT-like protein DUF972 PF06156.8 EAU93106.2 - 0.84 10.0 14.4 1.8 8.9 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EAU93106.2 - 0.92 9.2 12.8 0.44 10.2 2.0 2.7 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 EAU93106.2 - 1.2 8.9 11.5 0.099 12.4 0.4 3.2 3 1 0 3 3 3 0 Prefoldin subunit DUF4472 PF14739.1 EAU93106.2 - 1.2 9.6 13.3 1.4 9.4 1.6 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4472) Nup54 PF13874.1 EAU93106.2 - 1.4 8.5 15.6 0.17 11.5 2.8 2.8 2 1 0 3 3 3 0 Nucleoporin complex subunit 54 Ax_dynein_light PF10211.4 EAU93106.2 - 1.5 8.6 14.8 0.079 12.7 0.8 2.6 3 0 0 3 3 3 0 Axonemal dynein light chain CENP-F_leu_zip PF10473.4 EAU93106.2 - 1.5 8.6 14.9 1.1 9.1 5.1 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EAU93106.2 - 3.2 7.6 15.5 50 3.7 1.2 3.1 2 1 1 3 3 3 0 Tropomyosin like Rootletin PF15035.1 EAU93106.2 - 5.7 6.8 19.3 73 3.2 13.2 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Vac_Fusion PF02346.11 EAU93106.2 - 5.8 6.4 8.7 0.79 9.1 1.3 2.9 3 1 0 3 3 3 0 Chordopoxvirus fusion protein BLOC1_2 PF10046.4 EAU93106.2 - 6.6 6.9 12.0 46 4.2 0.5 3.6 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF904 PF06005.7 EAU93106.2 - 8.6 6.7 15.0 1.6 9.0 0.7 3.0 3 1 0 3 3 2 0 Protein of unknown function (DUF904) Mg_trans_NIPA PF05653.9 EAU93108.2 - 1.3e-20 73.5 13.5 3.1e-10 39.5 2.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DENN PF02141.16 EAU93109.1 - 2.9e-19 69.5 0.0 5.9e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain ADIP PF11559.3 EAU93109.1 - 0.0047 16.8 8.9 0.0047 16.8 6.2 2.4 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding IFT57 PF10498.4 EAU93109.1 - 0.086 11.5 10.3 0.19 10.4 7.2 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMCO5 PF14992.1 EAU93109.1 - 0.74 8.8 12.8 1.3 8.1 8.9 1.4 1 0 0 1 1 1 0 TMCO5 family DUF342 PF03961.8 EAU93109.1 - 0.77 8.1 5.5 1.6 7.0 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4200 PF13863.1 EAU93109.1 - 1.8 8.5 16.6 9.5 6.1 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1162 PF06650.7 EAU93110.2 - 4.8e-58 196.5 0.0 1.9e-53 181.4 0.0 4.1 3 1 1 4 4 4 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EAU93110.2 - 2.2e-31 107.8 0.3 7.2e-31 106.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EAU93110.2 - 3.4e-07 30.3 0.0 2.9e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain ELO PF01151.13 EAU93111.2 - 1.1e-59 201.8 20.5 1.2e-59 201.6 14.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2231 PF09990.4 EAU93111.2 - 0.84 10.0 9.6 0.65 10.3 0.3 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) RasGAP PF00616.14 EAU93112.2 - 8.6e-38 129.9 0.0 1.4e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PI3K_C2 PF00792.19 EAU93112.2 - 0.052 13.3 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 TraH_2 PF06871.6 EAU93112.2 - 0.12 11.8 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 TraH_2 Adaptin_N PF01602.15 EAU93113.2 - 1.1e-108 363.9 5.7 1.7e-108 363.2 3.9 1.3 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EAU93113.2 - 7.1e-37 125.8 0.0 1.7e-36 124.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EAU93113.2 - 5.7e-18 65.3 0.1 1.1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.17 EAU93113.2 - 0.11 12.5 0.3 9.9 6.5 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat HEAT PF02985.17 EAU93116.2 - 9.8e-39 127.9 12.2 0.00095 19.0 0.0 13.0 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.1 EAU93116.2 - 1.6e-29 101.9 6.4 9.2e-09 35.4 0.0 6.5 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EAU93116.2 - 3.9e-09 36.7 16.2 1.3 9.5 0.1 9.2 7 2 3 10 10 10 4 HEAT-like repeat Arm PF00514.18 EAU93116.2 - 2e-07 30.5 1.2 0.29 11.0 0.0 5.4 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EAU93116.2 - 0.14 12.7 2.0 32 5.3 0.0 5.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Aldose_epim PF01263.15 EAU93117.1 - 5.2e-32 111.1 0.0 5.9e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase EmrE PF13536.1 EAU93120.2 - 4.7e-11 42.8 8.2 4.7e-11 42.8 5.7 3.2 2 2 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EAU93120.2 - 0.00027 20.9 8.8 0.00027 20.9 6.1 3.8 2 2 1 3 3 3 1 EamA-like transporter family Metallophos PF00149.23 EAU93121.2 - 2.2e-41 141.4 0.2 3.3e-41 140.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ICE2 PF08426.5 EAU93122.2 - 1.3e-25 89.9 15.3 3.4e-14 52.2 3.1 3.0 1 1 2 3 3 3 3 ICE2 TctB PF07331.6 EAU93122.2 - 0.011 15.4 3.9 0.027 14.1 2.7 1.7 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family SNAP PF14938.1 EAU93124.1 - 5.3e-104 347.3 17.5 6e-104 347.1 12.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 EAU93124.1 - 0.0001 21.8 8.4 0.019 14.7 0.1 4.9 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU93124.1 - 0.00063 19.6 14.3 0.0017 18.2 2.9 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU93124.1 - 0.0007 19.1 13.3 0.098 12.3 3.0 3.9 3 1 1 4 4 4 3 TPR repeat Spatacsin_C PF14649.1 EAU93124.1 - 0.0045 15.8 2.7 0.016 14.1 1.9 1.8 1 1 0 1 1 1 1 Spatacsin C-terminus Clathrin PF00637.15 EAU93124.1 - 0.0087 15.6 1.8 0.023 14.3 0.1 2.4 3 1 0 3 3 3 1 Region in Clathrin and VPS TPR_6 PF13174.1 EAU93124.1 - 0.013 15.8 14.3 1.8 9.2 0.1 5.7 4 2 3 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU93124.1 - 0.096 12.6 2.0 17 5.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EAU93124.1 - 0.39 11.4 0.2 0.39 11.4 0.1 5.0 5 2 1 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EAU93124.1 - 1.7 8.4 10.4 1.3 8.7 0.2 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat NSF PF02071.15 EAU93124.1 - 3.1 8.7 15.5 2.8 8.8 0.1 6.3 7 1 0 7 7 5 0 Aromatic-di-Alanine (AdAR) repeat DUF2235 PF09994.4 EAU93126.2 - 8.1e-70 235.3 0.1 1e-69 234.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EAU93126.2 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EAU93127.2 - 5.4e-21 74.6 35.9 1.5e-13 50.1 13.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1228 PF06779.9 EAU93127.2 - 0.00062 19.7 2.5 0.29 11.1 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) Galactosyl_T PF01762.16 EAU93132.2 - 1.2e-08 34.7 0.0 0.00053 19.6 0.0 2.6 2 1 0 2 2 2 2 Galactosyltransferase GST_N_3 PF13417.1 EAU93133.1 - 4.3e-14 52.4 0.1 8.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU93133.1 - 4.1e-09 36.2 0.0 8.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EAU93133.1 - 3.4e-06 27.1 0.0 1.3e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EAU93133.1 - 6.7e-05 22.6 0.1 0.00014 21.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU93133.1 - 0.0001 22.1 0.0 0.00052 19.9 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain SGS PF05002.10 EAU93134.1 - 1.5e-30 104.7 3.7 2.2e-30 104.2 2.6 1.2 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EAU93134.1 - 4.3e-06 27.1 0.0 6.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 CS domain DHFR_1 PF00186.14 EAU93135.2 - 1.8e-23 82.8 0.3 1.9e-20 73.0 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase MoaE PF02391.12 EAU93137.1 - 2e-31 108.2 0.0 3.1e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 MoaE protein Rieske PF00355.21 EAU93138.2 - 1.9e-17 62.6 0.0 4.9e-17 61.2 0.0 1.8 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EAU93138.2 - 8.3e-17 61.1 0.9 2e-16 59.9 0.6 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region EF-hand_9 PF14658.1 EAU93138.2 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 EF-hand domain DUF4149 PF13664.1 EAU93139.2 - 7.8e-23 80.4 4.3 7.8e-23 80.4 3.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) LRR_9 PF14580.1 EAU93140.1 - 2.2e-61 206.4 0.5 3.1e-61 205.9 0.4 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EAU93140.1 - 2.5e-11 42.9 12.9 1.3e-06 27.9 3.3 3.3 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EAU93140.1 - 9e-10 38.1 5.8 5.3e-09 35.7 3.6 2.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EAU93140.1 - 2.6e-05 23.6 6.0 1.3 9.3 0.2 4.7 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EAU93140.1 - 0.0005 19.8 6.4 6.7 7.3 0.1 4.8 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EAU93140.1 - 0.21 11.7 6.2 22 5.5 1.4 4.1 3 1 1 4 4 4 0 Leucine Rich repeat Syja_N PF02383.13 EAU93141.1 - 2.1e-87 292.9 0.0 2.8e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF3829 PF12889.2 EAU93141.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) NAP PF00956.13 EAU93142.1 - 2e-34 118.7 8.0 5.1e-34 117.4 5.6 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Myc_N PF01056.13 EAU93142.1 - 0.35 9.9 3.5 0.69 9.0 2.5 1.4 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 EAU93142.1 - 3.9 7.7 13.3 0.56 10.4 5.5 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Polysacc_deac_1 PF01522.16 EAU93143.2 - 8.3e-27 93.2 0.0 1.4e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pertussis_S2S3 PF02918.10 EAU93144.2 - 0.012 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Pkinase PF00069.20 EAU93145.2 - 3e-62 210.1 0.0 4.4e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93145.2 - 2.5e-40 138.1 0.0 4e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU93145.2 - 1.3e-08 34.1 0.0 4.8e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EAU93145.2 - 0.028 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EAU93145.2 - 0.06 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CLTH PF10607.4 EAU93146.1 - 6.3e-37 126.4 0.0 7.6e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EAU93146.1 - 5.9e-06 25.8 0.2 1.3e-05 24.7 0.2 1.6 1 0 0 1 1 1 1 LisH TPR_16 PF13432.1 EAU93146.1 - 0.15 12.7 1.2 19 6.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Rrp15p PF07890.7 EAU93147.1 - 1.6e-18 67.0 11.6 1.6e-18 67.0 8.0 2.5 1 1 1 2 2 2 1 Rrp15p Hid1 PF12722.2 EAU93147.1 - 0.45 8.1 6.1 0.54 7.8 4.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DIL PF01843.14 EAU93148.1 - 3.1e-21 75.2 0.1 5.3e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.2 EAU93148.1 - 2.4e-08 34.2 0.0 6.9e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EAU93148.1 - 9e-07 28.4 0.0 0.013 15.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EAU93148.1 - 4.4e-05 23.8 0.1 0.0022 18.4 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU93148.1 - 8.5e-05 22.6 0.1 0.00099 19.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU93148.1 - 0.00033 20.5 0.1 0.024 14.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Zip PF02535.17 EAU93148.1 - 0.2 10.6 0.3 0.29 10.1 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Rhomboid PF01694.17 EAU93149.2 - 3.8e-37 127.5 15.6 2.7e-36 124.7 10.2 2.2 2 0 0 2 2 2 1 Rhomboid family DUF1426 PF07234.6 EAU93149.2 - 0.098 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) ATP1G1_PLM_MAT8 PF02038.11 EAU93149.2 - 0.12 11.3 0.0 0.37 9.8 0.0 1.8 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Cas1_AcylT PF07779.7 EAU93150.2 - 9.4e-175 581.7 14.3 2.2e-174 580.5 9.9 1.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EAU93150.2 - 3e-35 122.3 0.0 4.4e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Cut8_C PF08559.5 EAU93151.2 - 0.049 13.4 4.3 2.5 7.8 3.0 2.9 1 1 0 1 1 1 0 Cut8 six-helix bundle Mito_carr PF00153.22 EAU93153.2 - 1.9e-35 120.4 0.4 1.6e-13 50.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MHC2-interact PF09307.5 EAU93154.2 - 0.029 14.1 0.1 0.056 13.2 0.1 1.5 1 1 0 1 1 1 0 CLIP, MHC2 interacting Nucleoporin_C PF03177.9 EAU93155.2 - 6.6e-78 262.6 3.6 9.4e-78 262.1 2.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EAU93155.2 - 4.8e-58 196.8 0.1 7e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 EAU93156.2 - 6.6e-67 225.3 0.0 8.6e-67 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93156.2 - 4.3e-42 143.9 0.0 6.2e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU93156.2 - 1.6e-08 33.8 0.0 1.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EAU93156.2 - 0.0096 15.6 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EAU93156.2 - 0.01 14.9 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_6 PF08030.7 EAU93157.1 - 2.8e-25 89.0 0.0 5.9e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EAU93157.1 - 3.2e-21 75.1 0.0 6.9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EAU93157.1 - 1.6e-16 60.5 10.0 1.6e-16 60.5 6.9 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EAU93157.1 - 0.00014 21.9 0.0 0.00043 20.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EAU93157.1 - 0.0019 18.7 0.0 0.14 12.7 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain HORMA PF02301.13 EAU93158.2 - 5.8e-36 123.9 0.0 6.8e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EAU93158.2 - 0.047 13.1 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Autophagy-related protein 13 WD40 PF00400.27 EAU93159.2 - 9.1e-60 196.5 15.6 5.2e-12 45.1 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EAU93159.2 - 1.3e-32 112.7 0.0 5.2e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit LisH PF08513.6 EAU93159.2 - 0.0011 18.6 0.2 0.021 14.6 0.0 2.4 2 0 0 2 2 2 1 LisH Cytochrom_D1 PF02239.11 EAU93159.2 - 0.15 10.3 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain EphA2_TM PF14575.1 EAU93162.2 - 0.023 15.0 0.0 0.075 13.4 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 EAU93163.1 - 0.02 15.0 1.0 0.02 15.0 0.7 2.4 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DcuC PF03606.10 EAU93163.1 - 0.099 10.8 0.1 0.14 10.3 0.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier OAD_gamma PF04277.8 EAU93163.1 - 0.8 10.1 2.9 7.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Meth_synt_2 PF01717.13 EAU93164.2 - 2.5e-25 89.1 0.0 8e-25 87.4 0.0 1.8 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EAU93164.2 - 2.4e-08 33.6 0.0 0.012 14.8 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.13 EAU93165.1 - 3.8e-65 218.6 4.4 5.8e-65 218.1 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e FA_desaturase PF00487.19 EAU93166.1 - 3.4e-33 115.1 28.1 5.4e-33 114.5 19.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EAU93166.1 - 1.2e-09 37.7 0.0 5.3e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pal1 PF08316.6 EAU93167.1 - 5.9e-16 59.1 0.6 5.9e-16 59.1 0.4 2.2 2 0 0 2 2 2 1 Pal1 cell morphology protein His_biosynth PF00977.16 EAU93168.1 - 4.7e-42 143.8 0.1 4.3e-41 140.6 0.0 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EAU93168.1 - 8.5e-28 97.1 0.0 1.3e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EAU93168.1 - 1.3e-08 34.5 0.0 2.7e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EAU93168.1 - 1.2e-07 31.5 0.0 1.8e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 EAU93168.1 - 0.0054 16.1 0.0 0.4 10.0 0.0 2.6 3 0 0 3 3 3 1 Peptidase C26 Peptidase_S51 PF03575.12 EAU93168.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 2-Hacid_dh_C PF02826.14 EAU93169.1 - 9.7e-53 177.9 0.0 1.8e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EAU93169.1 - 1.5e-33 115.1 0.0 2.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EAU93169.1 - 0.00066 19.5 0.1 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2597 PF10772.4 EAU93169.1 - 0.0067 16.3 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2597) AdoHcyase_NAD PF00670.16 EAU93169.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Nitro_FeMo-Co PF02579.12 EAU93169.1 - 0.01 15.9 0.0 0.52 10.4 0.0 2.7 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor Rad51 PF08423.6 EAU93170.1 - 6.7e-135 447.9 0.0 8.3e-135 447.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EAU93170.1 - 7e-13 48.4 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EAU93170.1 - 5.3e-09 36.1 0.7 1.6e-08 34.6 0.5 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EAU93170.1 - 2e-07 30.4 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EAU93170.1 - 6.2e-06 25.4 0.0 1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 EAU93170.1 - 0.18 10.5 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 PAXNEB protein Ribosomal_L4 PF00573.17 EAU93171.1 - 3.9e-58 196.0 0.0 4.8e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 EAU93172.2 - 2.4e-39 134.3 0.3 2.7e-39 134.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRCT PF00533.21 EAU93173.2 - 0.0012 18.9 0.0 0.082 13.0 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Tim17 PF02466.14 EAU93174.1 - 1.4e-13 51.0 10.3 1.7e-13 50.7 7.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EAU93174.1 - 0.0012 18.9 2.6 0.0012 18.9 1.8 2.3 2 1 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide DUF1183 PF06682.7 EAU93174.1 - 0.12 11.9 0.5 0.12 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) WD40 PF00400.27 EAU93175.2 - 1.1e-14 53.6 5.2 6.4e-06 25.8 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Toprim_N PF08275.6 EAU93177.1 - 0.066 13.1 1.0 97 2.9 0.0 3.8 1 1 1 4 4 4 0 DNA primase catalytic core, N-terminal domain MdcG PF10620.4 EAU93177.1 - 0.22 11.0 2.3 3.4 7.1 0.1 2.3 1 1 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG SoxY PF13501.1 EAU93177.1 - 0.48 10.4 12.2 36 4.4 0.2 4.3 1 1 3 4 4 4 0 Sulfur oxidation protein SoxY NUC153 PF08159.7 EAU93178.1 - 7.8e-14 50.9 0.6 7.8e-14 50.9 0.4 3.4 3 0 0 3 3 3 2 NUC153 domain CS PF04969.11 EAU93179.1 - 3.5e-20 72.3 0.1 5.3e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 CS domain PHTB1_N PF14727.1 EAU93179.1 - 0.073 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 PTHB1 N-terminus DUF4404 PF14357.1 EAU93179.1 - 0.54 10.7 2.9 0.8 10.1 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) PINIT PF14324.1 EAU93180.2 - 7.1e-43 146.1 1.2 1.3e-42 145.3 0.8 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EAU93180.2 - 3.6e-15 55.2 6.6 7.4e-15 54.1 4.6 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EAU93180.2 - 1.1e-06 28.0 2.5 2.9e-06 26.6 1.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EAU93180.2 - 0.0042 16.5 0.5 0.023 14.2 0.0 2.4 2 0 0 2 2 2 1 SAP domain PAT1 PF09770.4 EAU93180.2 - 1.3 7.2 10.7 2 6.5 7.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 EAU93181.2 - 4.2e-66 218.7 6.2 5.3e-23 80.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.8 EAU93181.2 - 0.08 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 ResIII PF04851.10 EAU93182.2 - 3.3e-16 59.6 0.0 9.4e-16 58.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EAU93182.2 - 3.7e-15 55.8 0.0 6.5e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU93182.2 - 1e-14 54.0 0.0 2.4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 EAU93182.2 - 0.0002 20.4 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EAU93182.2 - 0.0041 17.2 0.0 0.011 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EAU93182.2 - 0.037 12.8 0.0 0.071 11.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain T2SE PF00437.15 EAU93182.2 - 0.08 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD_2 PF06733.10 EAU93182.2 - 0.13 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 NUDIX PF00293.23 EAU93184.2 - 2.2e-10 40.3 0.0 4.7e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain NPL4 PF05021.10 EAU93185.2 - 1.6e-94 316.5 0.0 2e-94 316.2 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EAU93185.2 - 3.9e-63 211.5 0.1 7.2e-63 210.6 0.1 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EAU93185.2 - 4.7e-05 23.5 0.0 9.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 bZIP_2 PF07716.10 EAU93186.2 - 4.4e-10 39.2 9.0 1e-09 38.0 6.2 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EAU93186.2 - 1.6e-05 24.7 9.7 0.00016 21.5 6.7 2.2 1 1 0 1 1 1 1 bZIP transcription factor PAT1 PF09770.4 EAU93186.2 - 0.007 14.6 1.8 0.0088 14.3 1.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 bZIP_Maf PF03131.12 EAU93186.2 - 0.013 15.7 3.5 0.032 14.5 2.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2216 PF10226.4 EAU93186.2 - 0.03 13.8 0.5 0.059 12.8 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) CHCH PF06747.8 EAU93187.1 - 4.7e-06 26.3 0.2 6.4e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EAU93187.1 - 0.061 13.3 0.3 0.085 12.9 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 GDPD PF03009.12 EAU93188.2 - 7.5e-28 97.7 0.0 2.9e-20 72.8 0.0 2.1 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EAU93188.2 - 1.5e-08 34.5 2.0 1e-07 31.9 0.5 2.5 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family ThiG PF05690.9 EAU93188.2 - 0.043 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG UPF0121 PF03661.8 EAU93190.2 - 1.7e-21 76.5 0.1 2.3e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Hpre_diP_synt_I PF07456.6 EAU93190.2 - 1.5 8.6 6.1 0.52 10.1 1.0 2.2 2 1 0 2 2 2 0 Heptaprenyl diphosphate synthase component I PTH2 PF01981.11 EAU93191.2 - 7e-43 145.0 0.0 9.3e-43 144.6 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF4552 PF15089.1 EAU93191.2 - 0.18 10.6 0.5 0.24 10.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Pkinase PF00069.20 EAU93192.1 - 3.7e-42 144.2 0.0 9e-22 77.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93192.1 - 3e-12 46.1 0.0 2e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF947 PF06102.7 EAU93194.2 - 9.9e-31 106.8 8.8 9.9e-31 106.8 6.1 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF947) Bcr-Abl_Oligo PF09036.5 EAU93194.2 - 0.37 10.7 6.9 0.085 12.8 2.1 1.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain CorA PF01544.13 EAU93195.2 - 2.2e-19 69.5 1.9 2.7e-08 33.2 0.0 3.5 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein Dynamitin PF04912.9 EAU93196.1 - 0.022 13.5 1.2 0.043 12.6 0.9 1.4 1 0 0 1 1 1 0 Dynamitin Baculo_PEP_C PF04513.7 EAU93196.1 - 0.031 14.0 0.2 0.052 13.3 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 EAU93196.1 - 0.19 10.7 4.5 0.28 10.1 3.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EAU93196.1 - 1.2 8.7 4.1 2.4 7.7 2.8 1.4 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EAU93196.1 - 1.8 8.9 4.3 1.3 9.4 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pex16 PF08610.5 EAU93197.2 - 2.4e-71 240.4 1.1 3e-71 240.1 0.7 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF866 PF05907.8 EAU93199.2 - 3.2e-48 163.2 0.3 3.5e-48 163.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) SprT-like PF10263.4 EAU93199.2 - 0.077 12.6 0.3 0.11 12.2 0.2 1.4 1 1 0 1 1 1 0 SprT-like family Lar_restr_allev PF14354.1 EAU93199.2 - 0.51 10.6 3.1 2.4 8.5 0.2 2.8 1 1 3 4 4 4 0 Restriction alleviation protein Lar MRP-S28 PF10213.4 EAU93200.2 - 5e-28 97.7 0.0 1e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Septin PF00735.13 EAU93202.1 - 2.7e-123 410.4 0.0 2.7e-123 410.4 0.0 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EAU93202.1 - 1.9e-07 31.0 0.0 4.3e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAU93202.1 - 2e-05 23.8 0.1 0.00011 21.4 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EAU93202.1 - 2.4e-05 23.8 1.6 0.0047 16.3 0.0 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EAU93202.1 - 0.00085 19.4 0.1 0.01 16.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.18 EAU93202.1 - 0.0027 17.5 4.4 0.97 9.2 0.1 3.2 2 1 0 3 3 3 2 Dynamin family AAA_10 PF12846.2 EAU93202.1 - 0.0028 17.1 0.0 0.0095 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EAU93202.1 - 0.0031 17.5 0.2 0.016 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.17 EAU93202.1 - 0.004 16.5 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EAU93202.1 - 0.0041 17.6 0.4 0.087 13.3 0.0 2.7 3 1 0 3 3 2 1 Miro-like protein AIG1 PF04548.11 EAU93202.1 - 0.0042 16.2 0.4 0.015 14.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 EAU93202.1 - 0.005 17.1 6.6 0.065 13.5 0.8 2.8 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EAU93202.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 EAU93202.1 - 0.062 13.1 1.5 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Strep_SA_rep PF06696.6 EAU93202.1 - 0.063 13.0 2.7 0.08 12.7 1.0 1.9 1 1 0 1 1 1 0 Streptococcal surface antigen repeat PduV-EutP PF10662.4 EAU93202.1 - 0.097 12.1 0.1 9.9 5.6 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Phage_GPO PF05929.6 EAU93202.1 - 0.13 11.4 4.1 0.24 10.6 2.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ATP_bind_1 PF03029.12 EAU93202.1 - 0.18 11.2 5.0 2.2 7.7 0.0 3.1 3 1 0 3 3 2 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 EAU93202.1 - 0.21 10.7 5.5 0.45 9.6 3.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit FtsK_SpoIIIE PF01580.13 EAU93202.1 - 0.3 10.5 2.6 0.3 10.5 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_24 PF13479.1 EAU93202.1 - 0.46 10.0 2.5 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EAU93202.1 - 0.56 9.7 6.1 1 8.9 4.2 1.4 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 EAU93202.1 - 8 6.7 13.0 4.4e+02 1.0 9.0 2.4 1 1 0 1 1 1 0 AAA domain Xpo1 PF08389.7 EAU93203.1 - 4.8e-21 75.2 0.0 7.8e-20 71.2 0.0 3.1 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EAU93203.1 - 8.1e-08 32.0 0.1 2.2e-06 27.4 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 EAU93203.1 - 0.00028 20.7 0.6 0.14 12.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EAU93203.1 - 0.0027 17.9 1.1 0.12 12.6 0.0 3.9 3 1 0 3 3 3 1 HEAT repeats EST1_DNA_bind PF10373.4 EAU93203.1 - 0.061 12.5 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain CoA_binding PF02629.14 EAU93204.2 - 1.7e-28 98.9 0.1 1.7e-28 98.9 0.1 2.4 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 EAU93204.2 - 4e-24 84.9 0.2 6.1e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EAU93204.2 - 1.7e-09 37.4 0.1 5.5e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EAU93204.2 - 1.1e-05 25.5 0.2 9.6e-05 22.5 0.0 2.5 3 0 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 EAU93204.2 - 9.6e-05 22.8 0.0 0.00033 21.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ACBP PF00887.14 EAU93205.1 - 1e-20 73.1 0.0 1.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.25 EAU93205.1 - 2.1e-16 58.8 0.0 3.7e-12 45.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EAU93205.1 - 2.6e-16 59.7 0.0 3.5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EAU93205.1 - 6.6e-16 58.3 0.1 1.4e-08 35.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EAU93205.1 - 9.4e-15 54.3 0.0 7.7e-14 51.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EAU93205.1 - 7.3e-11 41.2 0.0 3e-08 33.1 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat DUF1035 PF06281.7 EAU93205.1 - 0.062 13.0 0.6 0.097 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Ribosomal_S16 PF00886.14 EAU93206.1 - 8.7e-16 57.3 0.1 1.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 LSM PF01423.17 EAU93207.1 - 8.9e-21 73.2 0.2 1e-20 73.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EAU93207.1 - 0.018 14.9 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Arm PF00514.18 EAU93208.1 - 1.8e-92 300.3 10.7 2.8e-13 49.1 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EAU93208.1 - 4e-24 84.4 3.2 1.7e-09 37.8 0.0 5.5 5 0 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.1 EAU93208.1 - 1.2e-23 83.2 0.0 2.7e-08 33.9 0.0 5.9 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.17 EAU93208.1 - 1.3e-19 68.4 0.1 4.7e-05 23.1 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat IBB PF01749.15 EAU93208.1 - 1.9e-19 69.6 2.4 3.3e-19 68.8 1.7 1.3 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 EAU93208.1 - 4.9e-06 25.8 0.0 0.49 9.4 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EAU93208.1 - 5e-06 25.1 0.0 0.00025 19.5 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region RICTOR_V PF14668.1 EAU93208.1 - 5.5e-06 26.2 1.8 0.031 14.2 0.0 4.2 3 2 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 EAU93208.1 - 0.00017 21.7 1.2 0.57 10.8 0.0 4.5 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EAU93208.1 - 0.00056 19.8 0.0 0.63 9.9 0.0 4.5 4 2 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EAU93208.1 - 0.0096 14.2 0.0 0.79 7.9 0.0 2.6 3 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit COX6A PF02046.10 EAU93210.1 - 1.7e-29 102.0 0.3 2.2e-29 101.7 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ESSS PF10183.4 EAU93210.1 - 0.087 13.2 0.1 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ribul_P_3_epim PF00834.14 EAU93213.2 - 3.1e-64 215.7 0.0 3.8e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 EAU93213.2 - 0.00026 20.1 0.2 0.00034 19.7 0.1 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PG_binding_3 PF09374.5 EAU93213.2 - 0.038 13.9 0.1 0.098 12.6 0.1 1.7 1 1 0 1 1 1 0 Predicted Peptidoglycan domain OMPdecase PF00215.19 EAU93213.2 - 0.053 12.9 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Gly_transf_sug PF04488.10 EAU93214.2 - 0.00012 22.3 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EAU93214.2 - 0.017 14.3 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PK PF00224.16 EAU93215.1 - 2.4e-164 546.0 1.1 3.6e-164 545.4 0.7 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EAU93215.1 - 1.9e-32 111.2 0.1 8e-32 109.2 0.0 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EAU93215.1 - 4.7e-05 22.3 1.8 8.8e-05 21.4 0.7 1.9 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EAU93215.1 - 0.0011 17.9 0.2 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain MCM PF00493.18 EAU93216.1 - 5.9e-127 423.0 0.2 9.7e-127 422.3 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAU93216.1 - 9.3e-25 87.4 0.0 2.3e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAU93216.1 - 6e-08 32.0 0.1 1.6e-06 27.4 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EAU93216.1 - 0.0039 16.7 0.0 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF416 PF04222.7 EAU93216.1 - 0.0095 15.0 0.2 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF416) Sigma54_activat PF00158.21 EAU93216.1 - 0.015 14.7 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain WD40 PF00400.27 EAU93218.2 - 2.6e-42 141.2 10.9 4.5e-10 39.0 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EAU93218.2 - 0.00062 19.3 0.0 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 EAU93218.2 - 0.0016 16.8 0.0 0.64 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EAU93218.2 - 0.0093 14.1 0.6 0.6 8.1 0.1 2.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Myb_DNA-bind_6 PF13921.1 EAU93219.2 - 1.3e-20 73.2 0.0 4e-15 55.6 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EAU93219.2 - 2.8e-20 72.0 0.1 2.7e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain zf-C2H2 PF00096.21 EAU93219.2 - 0.00087 19.4 3.2 0.16 12.3 0.2 3.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EAU93219.2 - 0.0013 18.8 8.3 0.78 10.2 0.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger TPR_1 PF00515.23 EAU93220.2 - 1.6e-15 55.9 0.0 7e-09 34.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EAU93220.2 - 1.3e-14 53.5 0.2 2.6e-06 26.9 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EAU93220.2 - 5.1e-12 44.7 0.0 3.1e-06 26.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EAU93220.2 - 1.3e-07 31.2 0.8 0.017 15.2 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU93220.2 - 1.1e-06 28.6 0.4 0.00071 19.9 0.0 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EAU93220.2 - 2.1e-06 27.0 0.0 5.5e-05 22.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EAU93220.2 - 8.5e-06 25.6 0.0 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EAU93220.2 - 9.4e-06 25.0 0.0 0.00075 19.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EAU93220.2 - 4.8e-05 23.6 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU93220.2 - 0.00014 22.4 0.3 0.00033 21.2 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EAU93220.2 - 0.0054 16.5 0.1 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EAU93220.2 - 0.11 13.0 0.7 0.47 11.0 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat Prp19 PF08606.6 EAU93221.1 - 2.6e-28 97.5 2.4 4.6e-28 96.7 1.7 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EAU93221.1 - 1e-16 60.0 0.4 9.9e-05 22.0 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat U-box PF04564.10 EAU93221.1 - 0.00013 21.8 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 U-box domain Rtf2 PF04641.7 EAU93221.1 - 0.0012 18.1 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EAU93221.1 - 0.0035 16.8 0.0 0.0073 15.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 EAU93221.1 - 0.005 15.1 0.0 0.0092 14.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) OPT PF03169.10 EAU93222.2 - 8.3e-182 605.8 58.8 9.5e-182 605.7 40.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TauD PF02668.11 EAU93223.2 - 1.6e-54 185.3 0.8 2e-54 184.9 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0128 PF03673.8 EAU93223.2 - 0.042 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) F-box-like PF12937.2 EAU93224.2 - 1.3e-05 24.7 2.3 2.9e-05 23.7 1.0 2.1 2 0 0 2 2 2 1 F-box-like Spc7 PF08317.6 EAU93226.1 - 2.6e-46 157.7 9.9 2.6e-46 157.7 6.9 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EAU93226.1 - 0.0093 15.1 3.1 0.014 14.5 0.2 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Spc7_C2 PF15577.1 EAU93226.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 1 Spc7_C2 Fib_alpha PF08702.5 EAU93226.1 - 0.031 14.4 6.0 0.054 13.6 3.7 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family MAD PF05557.8 EAU93226.1 - 0.11 10.5 18.5 0.18 9.8 12.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF87 PF01935.12 EAU93226.1 - 0.39 10.5 5.8 0.13 12.0 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 Atg14 PF10186.4 EAU93226.1 - 1.8 7.4 10.2 3.7 6.3 7.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 EAU93226.1 - 2.1 8.3 17.2 0.25 11.3 8.4 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 EAU93226.1 - 2.5 5.8 6.9 3.9 5.2 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.4 EAU93226.1 - 8 5.0 20.4 0.042 12.6 6.3 2.5 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 Kinesin PF00225.18 EAU93227.2 - 1.3e-81 273.9 0.0 2.6e-81 272.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Nop14 PF04147.7 EAU93227.2 - 0.00042 18.3 36.4 0.00074 17.5 25.2 1.3 1 0 0 1 1 1 1 Nop14-like family NOA36 PF06524.7 EAU93227.2 - 0.5 9.5 13.8 1.1 8.4 9.6 1.6 1 0 0 1 1 1 0 NOA36 protein UDG PF03167.14 EAU93228.2 - 2.4e-17 62.8 0.0 3.8e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2808 PF10989.3 EAU93228.2 - 0.017 14.7 0.4 0.028 14.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Methyltransf_26 PF13659.1 EAU93229.2 - 1.7e-13 50.6 0.0 2.5e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU93229.2 - 6.3e-09 35.4 0.0 9.8e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EAU93229.2 - 8.1e-06 25.5 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU93229.2 - 1.5e-05 25.3 0.0 4.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU93229.2 - 0.00014 22.3 0.0 0.00025 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EAU93229.2 - 0.00028 21.2 0.0 0.0006 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EAU93229.2 - 0.01 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_18 PF12847.2 EAU93229.2 - 0.016 15.7 0.0 0.035 14.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EAU93229.2 - 0.081 13.7 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.5 EAU93229.2 - 0.1 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N6_Mtase PF02384.11 EAU93229.2 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase C2 PF00168.25 EAU93230.2 - 4.6e-74 244.3 8.0 7.6e-16 57.7 0.0 5.4 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EAU93230.2 - 0.054 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Mito_carr PF00153.22 EAU93231.2 - 4.1e-16 58.4 0.0 0.011 15.3 0.0 5.1 5 0 0 5 5 5 5 Mitochondrial carrier protein Mei4 PF13971.1 EAU93233.2 - 0.036 13.0 0.0 0.075 11.9 0.0 1.5 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 PHD PF00628.24 EAU93234.2 - 4.6e-11 42.2 8.6 7.9e-11 41.4 6.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EAU93234.2 - 0.00018 20.7 4.0 0.00032 19.9 2.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 EAU93234.2 - 0.0037 16.9 2.0 0.0084 15.7 1.4 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger Prok-RING_1 PF14446.1 EAU93234.2 - 0.059 13.1 6.5 0.027 14.2 2.7 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EAU93234.2 - 0.093 12.0 3.2 0.1 11.8 0.8 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain UvrD_C PF13361.1 EAU93235.2 - 1.7e-13 50.7 0.2 3.5e-10 39.8 0.0 3.2 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EAU93235.2 - 1.4e-06 27.8 0.1 1.4e-06 27.8 0.0 3.5 5 0 0 5 5 5 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EAU93235.2 - 7.5e-06 26.0 0.1 0.00016 21.7 0.0 3.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.1 EAU93235.2 - 0.0084 15.5 0.0 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAU93235.2 - 0.013 15.6 0.1 0.17 12.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.1 EAU93235.2 - 0.049 13.5 4.2 0.24 11.3 0.3 3.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EAU93235.2 - 0.053 13.3 2.4 1 9.3 0.5 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAU93235.2 - 0.075 12.6 13.3 0.93 9.1 0.2 4.3 4 1 0 4 4 4 0 TPR repeat TPR_1 PF00515.23 EAU93235.2 - 0.38 10.4 7.3 2.5 7.8 0.7 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EAU93235.2 - 2.3 9.0 12.2 11 6.8 0.9 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Spindle_Spc25 PF08234.7 EAU93236.2 - 1.2e-22 79.6 0.0 2.7e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Nup54 PF13874.1 EAU93236.2 - 0.0021 17.6 8.5 0.0031 17.1 5.9 1.2 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 APG6 PF04111.7 EAU93236.2 - 0.0063 15.6 11.4 0.0091 15.0 7.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 RTBV_P46 PF06216.6 EAU93236.2 - 0.013 14.3 2.4 0.017 13.9 1.7 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF4200 PF13863.1 EAU93236.2 - 0.021 14.7 11.7 0.039 13.9 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Phage_B PF02304.10 EAU93236.2 - 0.071 13.3 6.4 0.1 12.8 3.4 1.9 1 1 1 2 2 2 0 Scaffold protein B IncA PF04156.9 EAU93236.2 - 0.98 8.9 7.8 1.3 8.5 5.4 1.3 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EAU93236.2 - 5.3 7.4 9.9 8.2 6.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) LNP1 PF15419.1 EAU93236.2 - 8.9 6.3 10.8 64 3.5 6.9 2.0 1 1 1 2 2 2 0 Leukemia NUP98 fusion partner 1 bZIP_Maf PF03131.12 EAU93236.2 - 9.9 6.5 12.9 16 5.8 4.3 2.7 1 1 1 2 2 2 0 bZIP Maf transcription factor UPF0197 PF05251.7 EAU93240.1 - 1.7e-05 24.9 5.7 2.9e-05 24.2 3.9 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) Virul_fac_BrkB PF03631.10 EAU93240.1 - 0.064 12.5 4.0 0.072 12.4 2.8 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF4131 PF13567.1 EAU93240.1 - 0.66 9.3 5.1 0.79 9.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) QCR10 PF09796.4 EAU93240.1 - 1.3 8.7 4.6 9.4 5.9 0.5 2.1 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) TB2_DP1_HVA22 PF03134.14 EAU93241.1 - 1.4e-27 95.2 4.8 2.1e-27 94.6 3.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MFS_1 PF07690.11 EAU93242.2 - 4.8e-21 74.8 32.6 7.2e-21 74.2 22.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EAU93242.2 - 2.4e-13 49.8 7.7 2.4e-13 49.8 5.4 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 HAD_2 PF13419.1 EAU93243.1 - 9.3e-32 110.6 0.1 1.4e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 EAU93243.1 - 2.6e-06 27.7 0.0 0.0016 18.8 0.0 2.4 2 0 0 2 2 2 2 Prenyltransferase-like Hydrolase_like PF13242.1 EAU93243.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF3094 PF11293.3 EAU93243.1 - 0.067 12.6 0.5 0.14 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Prenyltrans PF00432.16 EAU93243.1 - 0.076 12.5 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat ArfGap PF01412.13 EAU93244.1 - 7.7e-43 144.9 0.2 1.2e-42 144.4 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DAO PF01266.19 EAU93246.1 - 7.4e-39 133.6 0.0 1.4e-38 132.7 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EAU93246.1 - 0.039 13.9 2.0 0.055 13.5 0.1 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EAU93246.1 - 0.06 13.2 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EAU93246.1 - 0.16 12.0 0.0 5 7.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EAU93246.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding RNA_pol_Rpb1_1 PF04997.7 EAU93247.2 - 8.7e-118 393.4 0.0 1.2e-117 392.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EAU93247.2 - 1.6e-103 345.8 0.0 2.5e-103 345.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EAU93247.2 - 1.2e-68 230.2 0.0 3.8e-68 228.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EAU93247.2 - 2.2e-68 229.6 0.3 4.2e-68 228.7 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EAU93247.2 - 1.1e-51 174.7 0.0 3.4e-51 173.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EAU93247.2 - 4e-44 149.5 0.4 1e-43 148.2 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EAU93247.2 - 1.9e-37 127.2 0.1 3.9e-37 126.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EAU93247.2 - 0.0052 16.8 173.9 0.017 15.1 2.8 12.9 8 2 2 12 12 12 9 RNA polymerase Rpb1 C-terminal repeat DUF4360 PF14273.1 EAU93248.2 - 5.8e-34 117.3 0.7 6.5e-20 71.5 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4360) DUF3515 PF12028.3 EAU93248.2 - 0.033 13.4 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) AMP-binding PF00501.23 EAU93249.2 - 6e-77 258.7 0.0 9.6e-77 258.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme CCER1 PF15482.1 EAU93249.2 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 D-ser_dehydrat PF14031.1 EAU93252.2 - 3.5e-15 55.9 0.0 2e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EAU93252.2 - 1.7e-13 50.6 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ras PF00071.17 EAU93253.2 - 4.5e-32 110.6 0.1 6.9e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EAU93253.2 - 2.4e-09 37.6 0.0 8.3e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EAU93253.2 - 0.036 14.2 0.0 0.06 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EAU93253.2 - 0.043 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 KaiC Chibby PF14645.1 EAU93253.2 - 0.057 13.3 0.4 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Chibby family Methyltransf_25 PF13649.1 EAU93253.2 - 0.075 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA_16 PF13191.1 EAU93253.2 - 0.085 12.8 0.7 0.17 11.8 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain SKG6 PF08693.5 EAU93254.2 - 0.23 10.8 0.5 0.55 9.6 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Nop14 PF04147.7 EAU93265.2 - 0.0029 15.6 19.2 0.0041 15.1 13.3 1.2 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EAU93265.2 - 0.014 14.7 18.4 0.025 13.8 12.8 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EAU93265.2 - 0.075 11.0 16.3 0.097 10.6 11.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Med14 PF08638.6 EAU93265.2 - 0.16 11.2 0.9 1.4 8.1 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit MED14 Med21 PF11221.3 EAU93265.2 - 0.65 9.9 0.0 0.65 9.9 0.0 3.9 3 1 1 4 4 4 0 Subunit 21 of Mediator complex RRN3 PF05327.6 EAU93265.2 - 0.97 7.4 10.2 1.3 7.0 7.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 EAU93265.2 - 1.4 7.8 11.9 2.1 7.3 8.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ndc1_Nup PF09531.5 EAU93265.2 - 2.9 6.1 5.9 3.8 5.8 4.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMS19_N PF14500.1 EAU93267.2 - 0.052 12.8 0.1 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II HMG_box_2 PF09011.5 EAU93267.2 - 1.6 9.1 5.7 1.1 9.6 0.2 2.9 2 0 0 2 2 2 0 HMG-box domain DUF4101 PF13355.1 EAU93268.2 - 0.049 14.0 1.8 0.14 12.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) Glycos_transf_2 PF00535.21 EAU93273.2 - 2.1e-32 112.1 0.0 2.8e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EAU93273.2 - 3.8e-13 49.7 0.0 5.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EAU93273.2 - 7.3e-09 35.1 0.0 9.4e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EAU93273.2 - 0.01 16.1 0.0 0.033 14.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EAU93273.2 - 0.11 11.7 0.0 0.21 10.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 F-box PF00646.28 EAU93274.2 - 2.1e-08 33.5 0.2 3.5e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU93274.2 - 4e-08 32.8 0.3 9e-08 31.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.6 EAU93274.2 - 6.3 7.2 7.6 2.2 8.7 2.3 2.2 2 1 1 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Sel1 PF08238.7 EAU93275.2 - 2.4e-23 82.0 5.7 2.4e-07 31.1 0.6 4.1 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.1 EAU93275.2 - 0.031 14.9 0.0 0.081 13.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU93275.2 - 0.082 12.8 1.8 11 6.2 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HA2 PF04408.18 EAU93276.2 - 8e-29 99.6 0.1 6e-28 96.8 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EAU93276.2 - 2e-24 85.5 0.0 6.6e-24 83.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EAU93276.2 - 9.1e-13 47.8 0.0 2.2e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EAU93276.2 - 5.1e-09 35.8 0.0 1.6e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EAU93276.2 - 2.5e-06 27.6 0.1 6.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EAU93276.2 - 0.0015 18.3 0.0 2.1 8.1 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EAU93276.2 - 0.0026 16.7 0.0 0.0054 15.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 EAU93276.2 - 0.0061 16.0 0.1 7.2 5.9 0.0 3.4 3 0 0 3 3 3 1 AAA-like domain DUF2075 PF09848.4 EAU93276.2 - 0.0064 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EAU93276.2 - 0.0097 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_14 PF13173.1 EAU93276.2 - 0.011 15.5 0.1 0.082 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EAU93276.2 - 0.013 15.2 0.1 0.056 13.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EAU93276.2 - 0.037 13.6 0.1 0.32 10.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EAU93276.2 - 0.044 14.0 0.0 0.19 12.0 0.0 2.1 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 EAU93276.2 - 0.061 12.5 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.17 EAU93276.2 - 0.065 12.6 0.2 0.18 11.1 0.1 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EAU93276.2 - 0.11 11.2 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 EAU93276.2 - 0.56 10.4 0.0 0.56 10.4 0.0 3.0 2 1 1 3 3 3 0 AAA domain L51_S25_CI-B8 PF05047.11 EAU93277.1 - 1.7e-06 27.6 0.0 2.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1895 PF08988.5 EAU93277.1 - 1.7 8.7 4.3 0.73 9.9 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1895) GET2 PF08690.5 EAU93278.2 - 0.00038 19.8 0.2 0.0011 18.2 0.0 1.8 2 0 0 2 2 2 1 GET complex subunit GET2 CAML PF14963.1 EAU93278.2 - 0.0029 16.9 2.2 0.38 10.0 0.1 2.2 2 0 0 2 2 2 2 Calcium signal-modulating cyclophilin ligand Vps35 PF03635.12 EAU93279.2 - 0 1026.1 0.0 0 1025.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 MFS_1 PF07690.11 EAU93280.1 - 9.6e-20 70.5 31.0 9.6e-20 70.5 21.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily BCIP PF13862.1 EAU93281.1 - 1.8e-64 216.8 0.0 2.7e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF4250 PF14056.1 EAU93281.1 - 0.057 13.1 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) DUF4360 PF14273.1 EAU93282.2 - 9.2e-16 58.0 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Nic96 PF04097.9 EAU93284.1 - 4.9e-134 447.7 0.0 6.7e-134 447.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ST7 PF04184.7 EAU93284.1 - 0.079 11.1 0.5 0.12 10.5 0.3 1.2 1 0 0 1 1 1 0 ST7 protein Actin PF00022.14 EAU93285.1 - 7e-46 156.4 0.0 1.4e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Actin Atrophin-1 PF03154.10 EAU93285.1 - 0.63 8.1 14.1 1.1 7.2 9.8 1.3 1 0 0 1 1 1 0 Atrophin-1 family IFP_35_N PF07334.8 EAU93285.1 - 2.5 8.1 6.4 0.18 11.7 0.4 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Ras PF00071.17 EAU93286.1 - 1.1e-64 216.7 0.0 1.3e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU93286.1 - 7.4e-20 71.6 0.0 1e-19 71.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EAU93286.1 - 1.4e-14 53.6 0.1 1.9e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EAU93286.1 - 6.6e-06 25.6 0.0 1.6e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EAU93286.1 - 1.4e-05 24.3 0.0 1.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EAU93286.1 - 0.00025 20.9 0.0 0.00042 20.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EAU93286.1 - 0.0078 15.5 0.0 0.4 9.9 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.1 EAU93286.1 - 0.032 14.2 0.1 0.047 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 EAU93286.1 - 0.034 13.3 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EAU93286.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EAU93286.1 - 0.049 13.7 0.0 0.098 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EAU93286.1 - 0.055 13.6 0.0 0.48 10.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EAU93286.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EAU93286.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 EAU93286.1 - 0.094 11.7 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Septin DUF4360 PF14273.1 EAU93296.2 - 5e-36 124.0 0.5 7e-36 123.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.11 EAU93297.2 - 9.1e-13 47.6 46.3 8.1e-07 28.0 12.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily YL1 PF05764.8 EAU93298.2 - 1.1e-19 71.0 28.3 1.1e-19 71.0 19.6 1.7 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EAU93298.2 - 4.6e-11 42.0 0.0 7.1e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain HrpB2 PF09487.5 EAU93298.2 - 1.5 9.0 5.1 23 5.1 0.4 2.6 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) DUF4360 PF14273.1 EAU93299.2 - 4.5e-46 156.8 0.9 5.2e-46 156.6 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DNA_methylase PF00145.12 EAU93300.2 - 3.7e-20 72.3 0.0 4.6e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Thiolase_N PF00108.18 EAU93301.1 - 1.6e-08 33.8 0.1 4.7e-07 29.0 0.0 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EAU93301.1 - 2e-07 30.4 0.1 2.3e-06 27.0 0.0 2.6 3 0 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EAU93301.1 - 0.00013 21.5 0.0 0.18 11.5 0.0 2.7 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EAU93301.1 - 0.00037 20.0 1.0 1.2 8.5 0.0 3.2 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain VHS PF00790.14 EAU93302.2 - 1e-43 148.3 3.9 1.7e-43 147.6 0.0 2.6 3 0 0 3 3 3 1 VHS domain FYVE PF01363.16 EAU93302.2 - 3e-17 62.2 6.1 5.4e-17 61.4 4.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EAU93302.2 - 0.00012 21.3 13.9 0.0044 16.4 2.7 3.1 3 0 0 3 3 3 2 Ubiquitin interaction motif DZR PF12773.2 EAU93302.2 - 0.84 9.5 7.5 9.2 6.1 2.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon Pro_dh PF01619.13 EAU93303.2 - 1.8e-34 119.1 0.0 1.4e-28 99.8 0.0 3.4 2 1 0 2 2 2 2 Proline dehydrogenase DUF4360 PF14273.1 EAU93304.1 - 1.5e-44 151.8 0.3 1.7e-44 151.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DEAD PF00270.24 EAU93305.2 - 4.7e-09 35.9 0.0 2e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU93305.2 - 1.8e-08 34.4 0.0 5.7e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pilus_CpaD PF09476.5 EAU93305.2 - 0.16 11.4 0.2 0.31 10.5 0.1 1.4 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) G-patch PF01585.18 EAU93306.2 - 4.6e-11 42.3 0.2 1.5e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 G-patch domain zf-C2H2_jaz PF12171.3 EAU93306.2 - 2.2e-06 27.6 6.2 3.6e-06 26.9 4.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.2 EAU93306.2 - 8.2e-06 25.5 0.0 8.2e-06 25.5 0.0 2.7 4 0 0 4 4 4 1 DExH-box splicing factor binding site zf-met PF12874.2 EAU93306.2 - 1.7e-05 24.8 2.2 2.8e-05 24.1 1.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EAU93306.2 - 0.0092 16.0 0.4 0.016 15.3 0.3 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EAU93306.2 - 0.044 14.0 1.2 0.083 13.2 0.8 1.4 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2 PF00096.21 EAU93306.2 - 0.45 10.9 2.5 0.83 10.1 1.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type PBP1_TM PF14812.1 EAU93308.1 - 0.24 11.7 4.7 0.49 10.7 3.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Frataxin_Cyay PF01491.11 EAU93309.1 - 2e-35 120.8 0.0 2.3e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain NACHT PF05729.7 EAU93311.2 - 1.8e-10 40.7 0.0 4.7e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU93311.2 - 0.00074 19.5 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EAU93311.2 - 0.001 19.2 0.0 0.0026 17.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAU93311.2 - 0.0034 17.1 0.0 0.0076 15.9 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EAU93311.2 - 0.012 15.7 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EAU93311.2 - 0.031 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EAU93311.2 - 0.033 13.0 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_PrkA PF08298.6 EAU93311.2 - 0.064 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RuvB_N PF05496.7 EAU93311.2 - 0.096 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EAU93311.2 - 0.1 11.4 0.0 0.51 9.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EAU93311.2 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Trypsin_2 PF13365.1 EAU93312.2 - 1.2e-08 34.9 0.0 4.1e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 EAU93312.2 - 0.19 11.2 0.7 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Trypsin Zip PF02535.17 EAU93313.1 - 0.0035 16.4 1.1 0.004 16.2 0.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 EAU93313.1 - 0.0061 15.9 5.1 0.0091 15.4 3.5 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region DUF2796 PF10986.3 EAU93313.1 - 0.13 12.2 22.3 0.2 11.5 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF2457 PF10446.4 EAU93313.1 - 0.22 10.2 5.6 0.28 9.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2946 PF11162.3 EAU93313.1 - 0.45 10.7 7.3 0.24 11.6 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) NOA36 PF06524.7 EAU93313.1 - 3 7.0 6.9 4.4 6.4 4.8 1.2 1 0 0 1 1 1 0 NOA36 protein Rhodanese PF00581.15 EAU93314.1 - 6.9e-19 68.2 0.0 1.3e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain NACHT PF05729.7 EAU93315.2 - 2.7e-13 49.9 0.0 4.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EAU93315.2 - 2.4e-05 24.4 0.0 9.8e-05 22.4 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EAU93315.2 - 2.9e-05 24.2 0.0 8.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EAU93315.2 - 0.00029 20.5 0.0 0.00071 19.3 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EAU93315.2 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EAU93315.2 - 0.0027 17.4 0.0 0.0065 16.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EAU93315.2 - 0.008 15.0 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain UPF0079 PF02367.12 EAU93315.2 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EAU93315.2 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 EAU93315.2 - 0.026 14.6 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EAU93315.2 - 0.027 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 EAU93315.2 - 0.029 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AFG1_ATPase PF03969.11 EAU93315.2 - 0.039 12.7 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase KAP_NTPase PF07693.9 EAU93315.2 - 0.041 12.8 0.1 0.26 10.2 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain RuvB_N PF05496.7 EAU93315.2 - 0.047 12.7 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EAU93315.2 - 0.05 12.2 0.0 0.07 11.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EAU93315.2 - 0.12 13.2 0.0 0.43 11.4 0.0 2.2 2 1 0 2 2 1 0 AAA domain Urb2 PF10441.4 EAU93316.2 - 2.4e-36 125.4 8.0 2.6e-36 125.3 0.1 3.7 3 0 0 3 3 3 1 Urb2/Npa2 family NST1 PF13945.1 EAU93316.2 - 0.69 9.9 3.4 5.4 7.0 0.1 3.1 3 0 0 3 3 3 0 Salt tolerance down-regulator KH_1 PF00013.24 EAU93319.1 - 2.4e-37 126.3 1.7 1.2e-08 34.4 0.0 6.8 7 0 0 7 7 7 4 KH domain KH_3 PF13014.1 EAU93319.1 - 1.6e-24 85.0 5.3 6.4e-06 25.6 0.0 6.8 7 0 0 7 7 7 4 KH domain Ku PF02735.11 EAU93320.2 - 7e-25 87.6 0.0 1.4e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EAU93320.2 - 2e-12 47.0 0.0 4.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 EAU93320.2 - 4.8e-10 39.2 0.0 1.4e-06 27.8 0.0 2.6 1 1 1 2 2 2 2 Ku70/Ku80 N-terminal alpha/beta domain SNF2_N PF00176.18 EAU93321.2 - 6.2e-83 278.0 1.5 6.2e-83 278.0 1.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EAU93321.2 - 4.8e-23 80.8 0.1 2e-22 78.8 0.0 2.1 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EAU93321.2 - 1.9e-18 66.0 0.3 1.4e-15 56.9 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain QLQ PF08880.6 EAU93321.2 - 1.5e-12 46.6 0.4 1.5e-12 46.6 0.3 2.1 2 0 0 2 2 2 1 QLQ HSA PF07529.8 EAU93321.2 - 4e-12 45.7 8.0 4e-12 45.7 5.5 3.8 3 0 0 3 3 3 1 HSA SnAC PF14619.1 EAU93321.2 - 1.7e-11 44.0 1.7 1.7e-11 44.0 1.2 3.8 2 1 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex bZIP_1 PF00170.16 EAU93322.2 - 1.3e-10 41.1 15.6 2.2e-10 40.3 10.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.5 EAU93322.2 - 2.1e-08 34.2 0.0 2.1e-08 34.2 0.0 4.1 1 1 1 3 3 1 1 Transcription factor PAP1 bZIP_2 PF07716.10 EAU93322.2 - 5.7e-05 22.8 16.3 5.7e-05 22.8 11.3 2.1 1 1 1 2 2 2 1 Basic region leucine zipper Zwint PF15556.1 EAU93322.2 - 0.012 14.9 5.5 0.019 14.2 3.8 1.4 1 0 0 1 1 1 0 ZW10 interactor Glutaredoxin2_C PF04399.8 EAU93322.2 - 0.021 14.4 1.9 0.041 13.4 1.3 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TSC22 PF01166.13 EAU93322.2 - 0.06 13.3 4.2 0.22 11.5 2.9 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 EAU93322.2 - 0.12 11.9 3.9 0.26 10.8 2.7 1.6 1 0 0 1 1 1 0 Septum formation initiator V_ATPase_I PF01496.14 EAU93322.2 - 0.16 9.7 4.7 0.22 9.3 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vac_Fusion PF02346.11 EAU93322.2 - 0.19 11.1 1.4 3.6 7.0 0.4 2.4 2 0 0 2 2 2 0 Chordopoxvirus fusion protein NICE-3 PF07406.6 EAU93322.2 - 0.31 10.4 1.3 0.53 9.7 0.9 1.2 1 0 0 1 1 1 0 NICE-3 protein DUF972 PF06156.8 EAU93322.2 - 3.1 8.1 7.0 1.7 9.0 3.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) TPR_11 PF13414.1 EAU93324.2 - 6.1e-51 169.9 29.7 3.3e-10 39.4 0.1 5.7 1 1 6 8 8 8 8 TPR repeat TPR_1 PF00515.23 EAU93324.2 - 2.5e-49 162.9 26.3 6.7e-08 31.8 0.0 9.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 EAU93324.2 - 8.7e-46 150.1 17.9 1.4e-05 24.6 0.1 9.7 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 EAU93324.2 - 1e-34 115.6 16.1 0.0012 18.4 1.8 9.3 7 1 2 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EAU93324.2 - 3.3e-31 107.0 16.0 1.4e-07 31.3 0.0 6.6 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EAU93324.2 - 2.6e-29 101.2 9.7 1.1e-05 25.9 0.2 6.2 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 EAU93324.2 - 1.3e-27 93.5 15.2 0.00011 22.1 0.2 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EAU93324.2 - 1.5e-27 93.5 5.7 0.015 15.8 0.0 9.1 2 2 7 9 9 9 8 Tetratricopeptide repeat TPR_7 PF13176.1 EAU93324.2 - 2.4e-25 86.2 11.0 0.025 14.3 0.2 8.6 7 1 1 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 EAU93324.2 - 2e-24 85.6 12.9 3e-06 27.4 0.5 5.9 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_6 PF13174.1 EAU93324.2 - 2.7e-20 71.3 13.1 0.037 14.5 0.0 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EAU93324.2 - 2.1e-15 56.6 9.4 5.6e-06 26.4 1.0 3.7 4 0 0 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EAU93324.2 - 5.3e-12 45.4 10.3 0.013 15.3 0.0 5.3 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_21 PF09976.4 EAU93324.2 - 3.6e-05 23.7 6.7 0.29 11.0 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EAU93324.2 - 3.6e-05 23.7 0.1 0.0042 17.1 0.1 3.6 2 2 2 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 EAU93324.2 - 0.00074 19.0 0.5 0.35 10.2 0.0 3.0 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 EAU93324.2 - 0.00093 18.4 9.1 2.4 7.2 0.0 4.5 2 2 2 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 EAU93324.2 - 0.0051 16.6 14.0 6.5 6.8 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 EAU93324.2 - 0.09 12.1 2.7 4 6.7 0.0 3.6 4 1 0 4 4 4 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 EAU93324.2 - 0.12 12.3 1.6 28 4.7 0.0 4.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EAU93324.2 - 3.6 7.4 28.4 2.2 8.1 0.4 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Brr6_like_C_C PF10104.4 EAU93327.2 - 4.2e-40 136.3 0.7 5.3e-40 136.0 0.5 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Ctr PF04145.10 EAU93327.2 - 0.014 15.4 0.0 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 Ctr copper transporter family DUF3328 PF11807.3 EAU93327.2 - 0.1 12.2 0.8 1.2 8.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) CLP_protease PF00574.18 EAU93328.2 - 6.8e-72 240.9 0.0 8.7e-72 240.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease Reprolysin_5 PF13688.1 EAU93329.2 - 1.9e-44 151.9 0.3 1.9e-44 151.9 0.2 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EAU93329.2 - 3.4e-38 131.4 1.5 8.2e-38 130.1 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EAU93329.2 - 7.5e-37 126.8 0.6 1.3e-36 126.0 0.0 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EAU93329.2 - 6.2e-19 68.7 0.0 1.6e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EAU93329.2 - 6.3e-17 61.5 20.8 6.3e-17 61.5 14.4 4.4 3 1 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 EAU93329.2 - 4e-07 29.8 3.7 4e-06 26.5 2.6 2.5 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EAU93329.2 - 0.00012 21.9 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Myc_target_1 PF15179.1 EAU93329.2 - 0.0083 15.7 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 Myc target protein 1 DEAD PF00270.24 EAU93330.1 - 1.3e-43 148.4 1.5 4.2e-42 143.4 0.0 3.2 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EAU93330.1 - 1.3e-28 98.6 0.0 1.2e-26 92.3 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EAU93330.1 - 0.00072 18.0 0.0 0.00072 18.0 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) MIP-T3 PF10243.4 EAU93330.1 - 0.0022 16.5 49.6 0.0034 15.9 34.4 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CMS1 PF14617.1 EAU93330.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 4.4 2 1 2 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit LytR_C PF13399.1 EAU93330.1 - 0.033 14.5 3.2 11 6.4 0.0 4.1 4 0 0 4 4 4 0 LytR cell envelope-related transcriptional attenuator Porph_ging PF09697.5 EAU93330.1 - 0.46 10.6 0.0 0.46 10.6 0.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (Porph_ging) Oxysterol_BP PF01237.13 EAU93331.2 - 1.6e-83 280.1 0.0 2.3e-83 279.6 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein NACHT PF05729.7 EAU93332.2 - 2.2e-10 40.4 0.0 4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 EAU93332.2 - 0.0003 20.9 0.0 0.00081 19.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EAU93332.2 - 0.00093 19.3 0.0 0.027 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU93332.2 - 0.0062 16.5 0.0 0.045 13.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EAU93332.2 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EAU93332.2 - 0.16 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EAU93332.2 - 0.23 10.2 0.0 0.37 9.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PAM2 PF07145.10 EAU93335.2 - 0.0046 16.3 1.9 3.4 7.3 0.1 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region Reo_sigmaC PF04582.7 EAU93335.2 - 0.67 9.0 34.0 0.31 10.1 1.7 4.6 2 1 3 5 5 5 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EAU93335.2 - 9.4 6.0 61.0 0.0077 16.0 12.7 4.8 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Aminotran_4 PF01063.14 EAU93336.2 - 3.6e-25 88.7 0.0 1.2e-24 87.1 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class IV RRM_6 PF14259.1 EAU93337.2 - 1e-13 51.0 0.0 6.5e-10 38.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EAU93337.2 - 1.9e-09 37.2 0.0 7.5e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EAU93337.2 - 2.5e-08 33.9 0.0 5.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 EAU93337.2 - 9.5e-06 25.1 6.3 1.7e-05 24.3 4.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EAU93337.2 - 0.00013 21.5 0.0 0.00089 18.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EAU93337.2 - 0.00024 20.9 2.6 0.017 14.9 0.0 2.7 3 0 0 3 3 3 2 RNA binding motif DUF3584 PF12128.3 EAU93337.2 - 0.6 7.3 5.0 0.83 6.8 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4613 PF15390.1 EAU93337.2 - 1.3 7.0 3.8 1.9 6.5 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Rhodanese PF00581.15 EAU93339.2 - 1.2e-19 70.7 0.0 3.9e-10 40.0 0.0 2.3 2 1 0 2 2 2 2 Rhodanese-like domain ACP_syn_III_C PF08541.5 EAU93339.2 - 0.087 12.8 0.1 9.9 6.2 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal V-ATPase_C PF03223.10 EAU93340.2 - 4.6e-114 381.1 0.1 5.5e-114 380.9 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit C TPR_10 PF13374.1 EAU93341.1 - 0.0015 18.3 0.8 1.3 9.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EAU93341.1 - 0.054 13.6 3.3 0.28 11.3 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ArsA_ATPase PF02374.10 EAU93342.1 - 4.7e-111 370.6 0.9 5.4e-111 370.4 0.6 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EAU93342.1 - 4.1e-15 55.6 0.0 6.2e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EAU93342.1 - 6.2e-09 35.9 0.0 1.4e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EAU93342.1 - 1.3e-05 24.5 0.1 3.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EAU93342.1 - 7.1e-05 22.3 0.5 0.0017 17.8 0.1 2.4 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 EAU93342.1 - 0.0009 18.6 0.0 0.0016 17.8 0.0 1.4 1 1 0 1 1 1 1 YhjQ protein MipZ PF09140.6 EAU93342.1 - 0.0083 15.2 0.1 0.025 13.6 0.0 1.7 1 1 1 2 2 2 1 ATPase MipZ AAA_25 PF13481.1 EAU93342.1 - 0.0091 15.4 0.3 0.041 13.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EAU93342.1 - 0.012 15.3 0.0 0.094 12.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 EAU93342.1 - 0.03 13.5 0.0 0.073 12.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein VirC1 PF07015.6 EAU93342.1 - 0.05 12.6 0.1 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 VirC1 protein IstB_IS21 PF01695.12 EAU93342.1 - 0.052 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DNA_pol_A PF00476.15 EAU93343.2 - 1.3e-94 317.0 0.0 1.8e-94 316.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EAU93343.2 - 0.0059 16.0 0.0 0.25 10.8 0.0 2.5 2 0 0 2 2 2 1 3'-5' exonuclease DltD_C PF04914.7 EAU93343.2 - 0.058 13.2 0.1 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 DltD C-terminal region MitoNEET_N PF10660.4 EAU93343.2 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Mnd1 PF03962.10 EAU93343.2 - 0.2 11.2 2.7 0.49 10.0 1.9 1.6 1 0 0 1 1 1 0 Mnd1 family UvrD_C PF13361.1 EAU93344.2 - 2.9e-13 50.0 0.0 2.4e-09 37.1 0.0 3.4 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EAU93344.2 - 2.6e-08 33.5 4.8 7.4e-08 32.0 0.1 3.2 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EAU93344.2 - 4.2e-05 23.6 0.0 0.001 19.1 0.0 2.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain SNAP PF14938.1 EAU93344.2 - 0.00042 19.5 7.6 0.00042 19.5 5.3 1.7 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP AAA_22 PF13401.1 EAU93344.2 - 0.0019 18.3 2.2 0.04 14.0 0.1 3.7 3 0 0 3 3 3 1 AAA domain Apc3 PF12895.2 EAU93344.2 - 0.0065 16.5 7.6 0.09 12.9 0.4 3.8 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_12 PF13087.1 EAU93344.2 - 0.01 15.2 0.0 0.031 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.1 EAU93344.2 - 1.2 9.0 8.3 15 5.6 0.6 3.6 2 1 0 2 2 2 0 Tetratricopeptide repeat DOT1 PF08123.8 EAU93345.2 - 1.8e-64 216.8 0.0 2.3e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EAU93345.2 - 0.00011 22.7 0.0 0.00019 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU93345.2 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF3398 PF11878.3 EAU93345.2 - 0.042 13.6 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) CMAS PF02353.15 EAU93345.2 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PBD PF00786.23 EAU93346.1 - 6.6e-20 71.2 1.1 8.1e-11 42.1 0.1 2.6 2 0 0 2 2 2 2 P21-Rho-binding domain PH PF00169.24 EAU93346.1 - 8.5e-11 41.9 0.1 3.9e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 PH domain Chs3p PF12271.3 EAU93347.1 - 5.8e-116 386.5 21.2 6.8e-116 386.3 14.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Cyclin PF08613.6 EAU93350.2 - 1.8e-18 67.3 0.0 5e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EAU93350.2 - 2.4e-10 40.0 0.0 4.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain SPO22 PF08631.5 EAU93351.2 - 5e-22 78.2 0.7 1.4e-13 50.5 0.1 3.2 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 EAU93351.2 - 0.0092 16.3 0.3 27 5.2 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EAU93351.2 - 0.02 15.0 3.0 1.2 9.3 0.8 3.6 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EAU93351.2 - 0.02 14.7 1.7 25 4.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EAU93351.2 - 0.048 13.3 0.0 0.4 10.3 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EAU93351.2 - 0.28 11.9 5.3 45 5.0 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EAU93351.2 - 2.9 8.0 4.8 54 4.0 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1793 PF08760.6 EAU93352.2 - 4.4e-17 62.4 0.1 6.8e-17 61.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Syndecan PF01034.15 EAU93352.2 - 0.0053 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain TRAPP PF04051.11 EAU93354.1 - 1.4e-29 102.5 0.0 1.9e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SR-25 PF10500.4 EAU93355.1 - 0.0011 18.4 1.8 0.0017 17.9 1.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Host_attach PF10116.4 EAU93355.1 - 0.043 14.0 1.3 0.071 13.3 0.9 1.3 1 0 0 1 1 1 0 Protein required for attachment to host cells Ndc1_Nup PF09531.5 EAU93355.1 - 0.57 8.5 2.1 0.64 8.3 1.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4360 PF14273.1 EAU93357.1 - 5.7e-25 88.0 2.1 6.9e-25 87.7 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF4360 PF14273.1 EAU93358.1 - 9.1e-19 67.8 0.1 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PCI PF01399.22 EAU93360.2 - 1.8e-07 31.4 0.7 4.4e-07 30.1 0.5 1.7 1 1 0 1 1 1 1 PCI domain DUF3407 PF11887.3 EAU93360.2 - 0.0068 15.7 0.5 0.0095 15.2 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3407) PSP1 PF04468.7 EAU93361.2 - 6.4e-33 112.6 0.3 1.2e-32 111.6 0.2 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-Apc11 PF12861.2 EAU93362.1 - 4.9e-40 135.2 13.0 6.2e-40 134.9 9.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EAU93362.1 - 1.6e-32 111.4 13.5 2.1e-32 111.0 9.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EAU93362.1 - 2.8e-06 27.0 15.7 1.5e-05 24.7 10.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAU93362.1 - 0.00092 19.1 5.6 0.00092 19.1 3.9 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EAU93362.1 - 0.011 15.3 13.1 0.081 12.6 8.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EAU93362.1 - 0.22 11.2 5.2 0.48 10.1 3.6 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 EAU93362.1 - 0.24 11.0 15.1 1.3 8.7 10.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EAU93362.1 - 0.32 10.5 3.7 0.55 9.7 2.6 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 EAU93362.1 - 0.66 9.6 6.9 1.2 8.8 4.8 1.5 1 0 0 1 1 1 0 HIT zinc finger FANCL_C PF11793.3 EAU93362.1 - 2.2 8.2 17.0 17 5.4 11.8 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Glyco_transf_25 PF01755.12 EAU93363.1 - 4.7e-10 39.4 0.0 9e-06 25.4 0.0 2.8 3 1 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) FKBP_C PF00254.23 EAU93364.2 - 1.4e-19 69.8 0.0 1.8e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Mem_trans PF03547.13 EAU93365.2 - 1.7e-34 118.7 12.2 1.6e-27 95.8 2.3 3.7 2 1 0 2 2 2 2 Membrane transport protein Methyltransf_31 PF13847.1 EAU93366.1 - 3.4e-17 62.4 0.0 4.4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EAU93366.1 - 4.3e-17 62.3 0.3 1.4e-16 60.6 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EAU93366.1 - 1.3e-12 47.9 0.0 2.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EAU93366.1 - 3.2e-12 47.0 0.0 4.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU93366.1 - 3.7e-12 46.5 0.0 6.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU93366.1 - 1.3e-08 34.8 0.0 2.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EAU93366.1 - 1.7e-08 34.0 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EAU93366.1 - 9.4e-08 32.3 0.0 1.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EAU93366.1 - 0.00012 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EAU93366.1 - 0.00013 21.2 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 EAU93366.1 - 0.0095 15.3 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.6 EAU93366.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 EAU93366.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EAU93366.1 - 0.074 12.3 0.0 2.2 7.5 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.7 EAU93366.1 - 0.095 12.2 0.0 0.18 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) APH PF01636.18 EAU93367.2 - 0.00045 20.0 0.3 0.0087 15.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAU93367.2 - 0.0012 18.0 0.0 0.0079 15.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain DUF605 PF04652.11 EAU93367.2 - 0.014 14.8 19.7 0.023 14.0 13.7 1.3 1 0 0 1 1 1 0 Vta1 like Choline_kinase PF01633.15 EAU93367.2 - 0.044 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2413 PF10310.4 EAU93367.2 - 0.51 9.0 9.8 0.96 8.1 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PAT1 PF09770.4 EAU93367.2 - 1.4 7.0 14.1 2.3 6.3 9.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 EAU93367.2 - 3 6.1 4.3 4.5 5.5 3.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup adh_short PF00106.20 EAU93368.2 - 1.3e-29 103.3 0.1 1.7e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EAU93368.2 - 6.7e-22 78.4 0.0 1.3e-21 77.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EAU93368.2 - 1.7e-14 53.8 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EAU93368.2 - 0.015 14.9 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GYD PF08734.6 EAU93368.2 - 0.015 14.9 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 GYD domain Caleosin PF05042.8 EAU93369.2 - 4.4e-35 120.7 0.0 5.8e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein APH PF01636.18 EAU93371.2 - 0.0025 17.6 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EAU93371.2 - 0.0042 16.2 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EAU93371.2 - 0.03 13.9 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF605 PF04652.11 EAU93371.2 - 0.1 11.9 11.9 0.16 11.3 8.2 1.3 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 EAU93371.2 - 0.84 9.6 6.1 7.5 6.6 4.5 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.2 EAU93371.2 - 1.3 6.6 3.0 1.7 6.1 2.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 EAU93371.2 - 1.9 8.1 6.0 3.2 7.3 4.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Gluconate_2-dh3 PF13618.1 EAU93372.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 N6-adenineMlase PF10237.4 EAU93373.1 - 1.8e-39 134.9 0.1 2.7e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_26 PF13659.1 EAU93373.1 - 0.0026 17.7 0.0 0.0072 16.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EAU93373.1 - 0.011 15.1 0.2 0.028 13.7 0.0 1.8 2 1 0 2 2 2 0 Conserved hypothetical protein 95 UPF0020 PF01170.13 EAU93373.1 - 0.068 12.7 0.0 0.4 10.2 0.0 2.0 1 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EAU93373.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Formyl_trans_N PF00551.14 EAU93374.2 - 3.6e-41 140.7 0.1 5.2e-20 71.7 0.0 2.0 2 0 0 2 2 2 2 Formyl transferase MannoseP_isomer PF01050.13 EAU93374.2 - 0.085 12.4 0.3 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Usp PF00582.21 EAU93374.2 - 0.12 12.5 0.6 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Universal stress protein family Pkinase PF00069.20 EAU93375.2 - 1e-30 106.7 0.0 1.4e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93375.2 - 6.9e-14 51.5 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU93375.2 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EAU93375.2 - 0.097 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L19e PF01280.15 EAU93376.1 - 2.7e-59 199.1 13.1 2.7e-59 199.1 9.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 EAU93376.1 - 0.01 15.2 0.0 0.035 13.5 0.0 1.9 1 0 0 1 1 1 0 S4 domain DUF3049 PF11250.3 EAU93376.1 - 0.039 13.7 1.2 0.43 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3049) Pkinase PF00069.20 EAU93377.2 - 7.8e-63 212.0 0.0 9.8e-63 211.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93377.2 - 1.7e-22 79.7 0.0 2.1e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU93377.2 - 4.4e-05 22.5 0.0 7.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EAU93378.2 - 3.4e-38 131.2 0.0 5.9e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93378.2 - 7.5e-17 61.2 0.0 1.4e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU93378.2 - 1.1e-06 27.8 0.0 1.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SYF2 PF08231.7 EAU93378.2 - 1.8 8.6 7.9 0.65 10.1 3.3 1.8 2 0 0 2 2 2 0 SYF2 splicing factor DUF4470 PF14737.1 EAU93379.1 - 1.1e-15 57.2 0.0 2.2e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EAU93379.1 - 1.4e-08 34.2 1.8 1.4e-07 31.0 0.7 2.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EAU93379.1 - 2.3e-05 23.9 2.1 0.0093 15.8 0.7 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EAU93379.1 - 0.084 12.5 1.8 1.9 8.2 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EAU93379.1 - 0.17 11.8 2.1 1 9.3 0.4 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF936 PF06075.7 EAU93380.1 - 0.36 9.7 30.9 0.47 9.3 21.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Rgp1 PF08737.5 EAU93381.2 - 2.3e-54 185.0 0.1 5.2e-54 183.9 0.1 1.5 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EAU93381.2 - 0.012 15.4 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EAU93381.2 - 0.017 15.2 0.0 0.73 9.9 0.0 2.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 EAU93381.2 - 0.32 10.3 0.0 0.6 9.4 0.0 1.3 1 0 0 1 1 1 0 SpoOM protein PLRV_ORF5 PF01690.12 EAU93383.1 - 0.56 9.2 10.6 0.72 8.9 7.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DEC-1_N PF04625.8 EAU93383.1 - 3 6.4 9.5 4.5 5.8 6.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Trm112p PF03966.11 EAU93388.1 - 7.5e-21 74.2 0.1 8.8e-21 74.0 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-NADH-PPase PF09297.6 EAU93388.1 - 0.0035 16.8 0.1 0.006 16.0 0.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 EAU93388.1 - 0.0038 16.9 0.2 0.0074 16.0 0.1 1.5 1 0 0 1 1 1 1 PhnA Zinc-Ribbon zf-RING_4 PF14570.1 EAU93388.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Gluconate_2-dh3 PF13618.1 EAU93389.1 - 0.1 12.7 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Pkinase PF00069.20 EAU93390.2 - 0.0038 16.4 0.0 0.0099 15.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EAU93390.2 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4218 PF13960.1 EAU93390.2 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Choline_kinase PF01633.15 EAU93390.2 - 0.16 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MOZ_SAS PF01853.13 EAU93391.2 - 6e-60 201.7 0.4 1.1e-59 200.8 0.2 1.4 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EAU93391.2 - 6.3e-06 25.8 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain F-box-like PF12937.2 EAU93396.1 - 1.6e-05 24.5 1.5 3.8e-05 23.3 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU93396.1 - 0.023 14.3 0.2 0.07 12.8 0.1 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EAU93397.1 - 6.8e-07 28.9 0.7 4.9e-06 26.1 0.2 2.7 2 0 0 2 2 2 1 F-box-like Pox_A_type_inc PF04508.7 EAU93397.1 - 0.6 10.0 2.5 1.9 8.4 1.7 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Mpv17_PMP22 PF04117.7 EAU93398.1 - 4.7e-25 87.0 0.1 9.5e-25 86.0 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Cas1_AcylT PF07779.7 EAU93399.1 - 0.022 13.2 0.9 0.032 12.6 0.6 1.2 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p SpoV PF08183.6 EAU93399.1 - 0.32 10.7 3.4 0.65 9.7 2.3 1.6 1 0 0 1 1 1 0 Stage V sporulation protein family DUF3020 PF11223.3 EAU93399.1 - 0.82 10.1 11.2 1.4 9.4 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3020) DDHD PF02862.12 EAU93399.1 - 6.4 6.5 8.0 9 6.0 5.5 1.2 1 0 0 1 1 1 0 DDHD domain DUF1700 PF08006.6 EAU93399.1 - 8.2 5.6 8.1 13 4.9 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) F-box-like PF12937.2 EAU93400.2 - 5.3e-08 32.4 1.4 2.7e-07 30.2 0.9 2.3 1 1 0 1 1 1 1 F-box-like EBV-NA3 PF05009.7 EAU93400.2 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) F-box PF00646.28 EAU93400.2 - 8.5 6.1 6.8 1.6 8.5 0.5 2.9 3 0 0 3 3 3 0 F-box domain CBS PF00571.23 EAU93401.2 - 1.6e-37 127.0 9.4 1.4e-09 37.5 0.0 5.3 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EAU93401.2 - 6.9e-08 32.0 0.0 1.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 PB1 domain DUF2992 PF11208.3 EAU93401.2 - 1.3 8.8 5.6 7.3 6.5 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2992) Pkinase PF00069.20 EAU93402.1 - 8.6e-54 182.4 0.0 2e-30 105.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93402.1 - 1.6e-38 132.2 0.0 5.8e-23 81.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EAU93402.1 - 0.0034 16.4 0.0 0.009 14.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAU93402.1 - 0.079 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF515 PF04415.7 EAU93402.1 - 8.8 4.4 11.6 14 3.7 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MitMem_reg PF13012.1 EAU93403.2 - 2.3e-21 76.0 0.0 3.3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EAU93403.2 - 6.8e-12 45.1 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MCM PF00493.18 EAU93404.1 - 1.8e-141 470.7 0.6 2.3e-141 470.4 0.4 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EAU93404.1 - 1.6e-20 73.7 0.3 4.8e-20 72.2 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EAU93404.1 - 7.9e-07 28.4 0.0 0.00024 20.3 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EAU93404.1 - 4e-05 23.3 0.0 9.7e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EAU93404.1 - 0.00069 19.2 0.1 0.0038 16.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EAU93404.1 - 0.012 15.9 0.6 0.17 12.3 0.2 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EAU93404.1 - 0.077 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNase_T PF00929.19 EAU93405.2 - 3.2e-09 37.2 0.0 5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease BATS PF06968.8 EAU93406.2 - 3.4e-30 103.7 0.0 8.9e-30 102.3 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EAU93406.2 - 2.4e-17 63.5 0.0 4.5e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF1509 PF07420.6 EAU93407.1 - 0.16 11.2 2.8 0.16 11.1 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) NP1-WLL PF11733.3 EAU93407.1 - 0.67 10.2 7.1 0.62 10.3 4.3 1.4 1 1 0 1 1 1 0 Non-capsid protein NP1 BTG PF07742.7 EAU93408.1 - 7.1e-11 41.6 0.0 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 BTG family RAP1 PF07218.6 EAU93408.1 - 1.5 6.8 7.9 2.2 6.2 5.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S27e PF01667.12 EAU93409.1 - 1.3e-29 101.4 5.3 1.6e-29 101.2 3.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EAU93409.1 - 0.00032 20.4 1.9 0.00038 20.2 1.3 1.2 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EAU93409.1 - 0.032 13.5 2.2 0.046 13.0 1.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding PhnA_Zn_Ribbon PF08274.7 EAU93409.1 - 0.049 13.4 0.3 0.084 12.6 0.2 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-C2H2_4 PF13894.1 EAU93411.1 - 6.5e-09 35.5 10.5 9.9e-05 22.4 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EAU93411.1 - 1.1e-08 34.8 19.6 5.6e-06 26.3 0.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU93411.1 - 0.00014 21.9 13.7 0.002 18.3 1.5 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EAU93411.1 - 0.0038 17.3 7.0 0.015 15.4 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU93411.1 - 0.58 10.4 7.6 0.7 10.1 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EAU93411.1 - 4.1 7.2 12.0 2.7 7.8 0.9 3.3 2 1 1 3 3 3 0 BED zinc finger zf-H2C2_5 PF13909.1 EAU93411.1 - 6.4 7.2 7.2 2 8.8 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Med6 PF04934.9 EAU93412.2 - 2.1e-37 127.8 0.2 2.9e-37 127.3 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Clat_adaptor_s PF01217.15 EAU93413.1 - 2e-38 131.2 0.0 1.5e-32 112.2 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain SGT1 PF07093.6 EAU93414.2 - 1.1e-125 420.3 17.5 1.3e-118 396.9 0.0 2.7 2 1 1 3 3 3 2 SGT1 protein ATP-synt_F PF01990.12 EAU93415.1 - 3.9e-31 107.2 0.2 4.5e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 EAU93415.1 - 0.051 12.5 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TIM21 PF08294.6 EAU93416.2 - 2.5e-21 75.8 0.0 1.9e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 TIM21 DUF1180 PF06679.7 EAU93416.2 - 1.4 8.7 4.6 6.6 6.5 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Histone PF00125.19 EAU93417.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EAU93417.1 - 1.3e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EAU93417.1 - 0.00068 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EAU93417.1 - 0.016 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EAU93417.1 - 0.092 11.9 1.2 0.1 11.8 0.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PhyH PF05721.8 EAU93418.2 - 0.00012 22.1 0.1 0.003 17.6 0.1 2.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Chalcone PF02431.10 EAU93419.1 - 5.9e-28 97.6 0.0 1e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone-flavanone isomerase zf-CCCH PF00642.19 EAU93423.1 - 1.1e-19 69.6 14.0 3e-11 42.7 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EAU93423.1 - 0.013 15.4 9.8 0.018 15.0 0.3 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Choline_kinase PF01633.15 EAU93424.2 - 4.1e-51 173.5 0.0 6e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EAU93424.2 - 3.4e-13 49.8 0.0 5.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EAU93424.2 - 0.0083 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase MFS_1 PF07690.11 EAU93425.2 - 8.3e-39 133.2 53.5 1.3e-37 129.3 37.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU93425.2 - 3.5e-11 42.3 8.2 3.5e-11 42.3 5.7 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter CTDII PF01556.13 EAU93426.2 - 1.8e-29 101.4 0.3 3.4e-22 78.1 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EAU93426.2 - 1e-24 85.9 2.5 1.6e-24 85.4 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EAU93426.2 - 1.2e-08 34.8 18.9 1.2e-08 34.8 13.1 1.9 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EAU93426.2 - 4.4 7.0 8.7 5.7 6.6 1.0 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family MSSP PF03940.8 EAU93426.2 - 7.2 6.0 18.9 5.8 6.3 4.7 2.6 2 0 0 2 2 2 0 Male specific sperm protein Pkinase PF00069.20 EAU93427.2 - 7e-58 195.7 0.1 9.4e-58 195.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93427.2 - 1.2e-20 73.6 0.0 1.8e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EAU93427.2 - 7.8e-07 29.0 0.1 8e-05 22.4 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EAU93427.2 - 0.014 14.9 0.1 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase KicB PF03882.9 EAU93427.2 - 0.077 11.6 0.1 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 KicB killing factor CBM_5_12 PF02839.9 EAU93428.2 - 2.1e-17 62.4 23.7 3.8e-10 39.1 5.2 3.9 3 0 0 3 3 3 2 Carbohydrate binding domain CBM_5_12_2 PF14600.1 EAU93428.2 - 9.1e-05 22.0 15.0 0.018 14.6 2.0 2.8 2 0 0 2 2 2 2 Cellulose-binding domain Mito_fiss_reg PF05308.6 EAU93428.2 - 0.027 13.8 3.2 0.043 13.1 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Mucin PF01456.12 EAU93428.2 - 0.052 13.3 22.5 0.099 12.4 15.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EAU93428.2 - 4.7 5.0 19.9 7.8 4.3 13.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DNA_pol_A_exo1 PF01612.15 EAU93429.2 - 3.5e-16 59.1 0.0 5.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease zf-C3HC4 PF00097.20 EAU93431.2 - 4.8e-05 22.9 3.6 4.8e-05 22.9 2.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EAU93431.2 - 5.2e-05 22.8 3.8 5.2e-05 22.8 2.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EAU93431.2 - 0.0004 20.1 7.5 0.0004 20.1 5.2 2.0 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EAU93431.2 - 0.00061 19.7 7.0 0.00061 19.7 4.9 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EAU93431.2 - 0.0011 18.5 2.1 0.0011 18.5 1.4 1.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EAU93431.2 - 0.0015 18.2 3.0 0.0015 18.2 2.1 2.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-UDP PF14569.1 EAU93431.2 - 0.0034 17.0 0.1 0.0083 15.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger DZR PF12773.2 EAU93431.2 - 0.031 14.1 2.6 0.031 14.1 1.8 2.1 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.1 EAU93431.2 - 0.4 10.4 4.9 0.27 10.9 1.5 2.2 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EAU93431.2 - 0.8 9.6 5.2 2.2 8.2 3.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PQQ PF01011.16 EAU93432.1 - 0.11 12.1 0.1 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat DcpS_C PF11969.3 EAU93435.2 - 0.00019 21.6 0.8 0.00055 20.1 0.6 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2413 PF10310.4 EAU93439.1 - 2.5e-78 263.8 14.1 1.1e-77 261.7 9.8 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) Complex1_30kDa PF00329.14 EAU93440.2 - 9e-36 122.2 0.1 1.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.6 EAU93441.1 - 1.4e-68 230.7 6.7 1.5e-68 230.5 4.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.4 EAU93441.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor APG6 PF04111.7 EAU93441.1 - 2.9 6.8 10.7 1.7 7.6 6.2 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 NARP1 PF12569.3 EAU93442.2 - 1.4 7.6 8.4 2.2 6.9 5.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3987 PF13148.1 EAU93442.2 - 9 4.7 14.3 21 3.5 9.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) 4HBT_3 PF13622.1 EAU93444.2 - 1.8e-23 83.6 0.0 2.4e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EAU93444.2 - 7.5e-17 61.2 0.0 3.5e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 Acyl-CoA thioesterase ATP-grasp_2 PF08442.5 EAU93446.2 - 1.1e-73 246.9 0.5 2e-73 246.1 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EAU93446.2 - 3.6e-27 94.8 0.1 9.3e-27 93.5 0.1 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EAU93446.2 - 1.6e-13 50.4 0.6 1.1e-12 47.6 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EAU93446.2 - 0.00011 21.7 0.1 0.0003 20.3 0.1 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EAU93446.2 - 0.00034 20.3 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PASTA PF03793.14 EAU93446.2 - 0.016 14.8 0.1 8 6.1 0.0 2.9 2 0 0 2 2 2 0 PASTA domain DinB_2 PF12867.2 EAU93447.2 - 2.4e-06 27.9 0.3 3.2e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 DinB superfamily TraC_F_IV PF11130.3 EAU93447.2 - 0.041 13.3 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer Rogdi_lz PF10259.4 EAU93447.2 - 0.12 11.4 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Hist_deacetyl PF00850.14 EAU93448.2 - 1.2e-82 277.7 0.0 1.6e-82 277.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Tim17 PF02466.14 EAU93449.1 - 6.4e-25 87.6 0.1 1e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ras PF00071.17 EAU93451.2 - 8e-44 148.8 0.1 1.2e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EAU93451.2 - 9.3e-13 48.7 0.0 2e-12 47.6 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EAU93451.2 - 7.2e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EAU93451.2 - 0.0024 17.1 0.1 0.074 12.3 0.0 2.5 1 1 2 3 3 3 1 Ferrous iron transport protein B AAA_24 PF13479.1 EAU93451.2 - 0.04 13.4 0.1 0.086 12.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EAU93451.2 - 0.063 12.1 0.0 0.84 8.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.11 EAU93451.2 - 0.074 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Yippee-Mis18 PF03226.9 EAU93453.2 - 1.1e-15 57.4 1.0 1.6e-15 56.8 0.7 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EAU93453.2 - 0.048 13.5 2.9 0.67 9.9 0.2 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EAU93453.2 - 0.23 11.2 1.3 0.61 9.9 0.1 2.2 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 EAU93453.2 - 0.25 10.8 1.4 0.32 10.5 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S27 PhoU_div PF01865.11 EAU93454.1 - 0.018 14.2 0.0 0.02 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF47 Peptidase_C48 PF02902.14 EAU93455.2 - 8.7e-34 117.0 0.1 1.5e-33 116.3 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LacI PF00356.16 EAU93455.2 - 0.078 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family 4HBT_3 PF13622.1 EAU93458.1 - 3.4e-44 151.4 1.2 4e-44 151.2 0.8 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Beta_elim_lyase PF01212.16 EAU93459.1 - 1.8e-73 247.2 0.0 3e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EAU93459.1 - 8.3e-06 24.9 0.0 1.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EAU93459.1 - 0.0026 16.0 0.0 0.0034 15.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EAU93459.1 - 0.0083 15.2 0.0 0.037 13.0 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.15 EAU93459.1 - 0.046 12.2 0.2 0.068 11.7 0.1 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain zf-met2 PF12907.2 EAU93460.1 - 6.7e-17 61.1 2.2 8.9e-17 60.7 1.5 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EAU93460.1 - 1e-07 32.5 8.5 1e-07 32.5 5.9 1.8 2 0 0 2 2 2 1 4F5 protein family WD40 PF00400.27 EAU93462.1 - 4.3e-14 51.7 20.7 0.0038 17.0 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF2632 PF10943.3 EAU93462.1 - 0.24 10.8 0.1 0.44 10.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) Sigma70_ner PF04546.8 EAU93462.1 - 8.8 5.8 11.3 2.1 7.9 0.1 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region F-box-like PF12937.2 EAU93463.1 - 2.6e-10 39.8 0.3 5.7e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU93463.1 - 0.0048 16.5 2.4 0.17 11.6 0.2 2.6 2 0 0 2 2 2 2 F-box domain F-box-like_2 PF13013.1 EAU93463.1 - 1.9 8.2 5.2 2.7 7.7 2.1 2.5 2 1 0 2 2 2 0 F-box-like domain zf-C2H2_3 PF13878.1 EAU93464.2 - 8.1 6.1 7.7 11 5.6 0.1 3.2 2 1 1 3 3 3 0 zinc-finger of acetyl-transferase ESCO 2-oxoacid_dh PF00198.18 EAU93468.1 - 2e-38 131.9 0.0 1.4e-37 129.2 0.0 2.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EAU93468.1 - 1e-19 69.8 0.3 3.1e-19 68.3 0.1 1.9 1 1 1 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EAU93468.1 - 2e-06 27.3 0.1 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EAU93468.1 - 0.023 14.3 0.2 0.13 11.9 0.2 2.3 1 1 1 2 2 2 0 Biotin-lipoyl like Med21 PF11221.3 EAU93470.1 - 1.2e-24 86.9 5.2 1.6e-24 86.5 3.6 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF3391 PF11871.3 EAU93470.1 - 0.05 13.8 2.3 0.33 11.1 1.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DEAD PF00270.24 EAU93471.1 - 3e-13 49.6 0.0 3.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EAU93471.1 - 0.0029 17.4 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ifi-6-16 PF06140.8 EAU93472.1 - 0.0062 16.2 19.0 0.015 15.0 13.2 1.7 1 1 0 1 1 1 1 Interferon-induced 6-16 family Glyco_trans_2_3 PF13632.1 EAU93472.1 - 0.4 10.3 3.2 0.48 10.1 2.1 1.4 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Ifi-6-16 PF06140.8 EAU93473.1 - 0.0012 18.5 9.3 0.0012 18.5 6.4 2.2 1 1 1 2 2 2 1 Interferon-induced 6-16 family DUF883 PF05957.8 EAU93474.1 - 2.7 8.4 11.3 1 9.8 3.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ifi-6-16 PF06140.8 EAU93475.1 - 0.00066 19.4 19.3 0.00066 19.4 13.4 3.6 4 0 0 4 4 4 1 Interferon-induced 6-16 family VirionAssem_T7 PF11653.3 EAU93475.1 - 0.037 14.7 2.7 0.037 14.7 1.9 3.5 2 1 2 4 4 4 0 Bacteriophage T7 virion assembly protein Apolipoprotein PF01442.13 EAU93475.1 - 0.045 13.2 1.1 0.79 9.1 0.8 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain WD40 PF00400.27 EAU93477.2 - 0.0027 17.5 2.9 2.5 8.1 0.0 5.2 7 0 0 7 7 7 1 WD domain, G-beta repeat DUF2415 PF10313.4 EAU93477.2 - 0.03 13.9 0.0 0.086 12.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Rtf2 PF04641.7 EAU93478.2 - 5.6e-71 238.7 4.3 6.9e-71 238.4 3.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger BRF1 PF07741.8 EAU93478.2 - 1.8 8.8 11.2 0.28 11.4 0.7 2.6 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Herpes_DNAp_acc PF04929.7 EAU93478.2 - 6.4 5.6 8.0 8.5 5.2 5.5 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MMR_HSR1 PF01926.18 EAU93479.1 - 1.4e-08 34.6 0.0 2.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EAU93479.1 - 0.00017 20.8 0.0 0.00064 18.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EAU93479.1 - 0.00018 20.7 0.0 0.0011 18.0 0.0 2.0 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EAU93479.1 - 0.001 18.9 0.0 0.36 10.6 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_33 PF13671.1 EAU93479.1 - 0.0076 16.1 0.0 0.021 14.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain FAM74 PF15026.1 EAU93479.1 - 0.0078 15.8 0.1 0.03 13.9 0.1 1.9 2 0 0 2 2 2 1 FAM74 protein AAA_22 PF13401.1 EAU93479.1 - 0.0092 16.1 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EAU93479.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_10 PF12846.2 EAU93479.1 - 0.089 12.2 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Pollen_allerg_2 PF01620.11 EAU93480.2 - 0.047 14.0 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) YopD PF05844.7 EAU93480.2 - 0.11 11.4 0.1 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 YopD protein MMR_HSR1 PF01926.18 EAU93481.2 - 6.7e-09 35.7 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU93481.2 - 1.3e-06 28.3 0.1 0.00014 21.7 0.0 2.3 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 EAU93481.2 - 6.1e-05 22.2 0.0 0.00018 20.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EAU93481.2 - 0.0011 19.0 0.0 0.0033 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EAU93481.2 - 0.0012 19.3 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EAU93481.2 - 0.0028 16.5 0.0 0.0066 15.3 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EAU93481.2 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_33 PF13671.1 EAU93481.2 - 0.019 14.8 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EAU93481.2 - 0.021 14.2 0.0 0.075 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Septin PF00735.13 EAU93481.2 - 0.024 13.6 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Septin DUF732 PF05305.9 EAU93481.2 - 0.032 14.2 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF732) ABC_tran PF00005.22 EAU93481.2 - 0.051 13.8 0.1 0.077 13.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.7 EAU93481.2 - 0.075 12.6 0.4 6.8 6.3 0.1 2.7 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.1 EAU93481.2 - 0.21 12.4 0.9 0.52 11.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EAU93481.2 - 0.28 10.9 0.6 0.59 9.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EAU93483.1 - 3.5e-09 36.6 0.0 9.7e-09 35.1 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.13 EAU93483.1 - 5.7e-06 25.5 0.0 1.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Septin AAA_22 PF13401.1 EAU93483.1 - 7.5e-06 26.1 0.1 1.8e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EAU93483.1 - 1.2e-05 24.5 0.0 2.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EAU93483.1 - 0.00034 21.1 0.3 0.005 17.3 0.0 2.5 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EAU93483.1 - 0.00045 20.0 2.8 0.029 14.1 0.0 2.8 1 1 2 3 3 3 1 Dynamin family AAA_33 PF13671.1 EAU93483.1 - 0.00055 19.8 0.1 0.0016 18.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.11 EAU93483.1 - 0.00086 18.4 0.6 0.0016 17.6 0.0 1.6 1 1 1 2 2 2 1 AIG1 family SRPRB PF09439.5 EAU93483.1 - 0.0014 17.8 2.0 0.0017 17.6 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EAU93483.1 - 0.0015 18.8 2.7 0.5 10.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU93483.1 - 0.0023 17.9 0.2 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.17 EAU93483.1 - 0.0024 17.2 0.8 0.018 14.4 0.5 2.1 1 1 0 1 1 1 1 Ras family ATP_bind_1 PF03029.12 EAU93483.1 - 0.003 17.1 2.3 0.38 10.2 0.1 2.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein KaiC PF06745.8 EAU93483.1 - 0.0092 15.1 0.3 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 KaiC Rad17 PF03215.10 EAU93483.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein VirE PF05272.6 EAU93483.1 - 0.014 14.8 1.6 0.23 10.9 0.0 2.6 3 0 0 3 3 3 0 Virulence-associated protein E NACHT PF05729.7 EAU93483.1 - 0.015 14.9 0.3 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_17 PF13207.1 EAU93483.1 - 0.018 15.8 2.5 0.071 13.9 1.5 2.3 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EAU93483.1 - 0.019 14.0 0.8 0.045 12.8 0.1 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EAU93483.1 - 0.022 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EAU93483.1 - 0.025 14.8 0.6 0.13 12.5 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 EAU93483.1 - 0.029 14.2 0.1 0.19 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EAU93483.1 - 0.042 12.7 0.0 0.089 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 EAU93483.1 - 0.051 13.2 0.1 0.16 11.6 0.1 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EAU93483.1 - 0.066 13.3 0.3 0.22 11.7 0.2 2.0 1 1 0 1 1 1 0 RNA helicase HALZ PF02183.13 EAU93483.1 - 0.22 11.2 3.3 7 6.4 0.0 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper AAA_18 PF13238.1 EAU93483.1 - 0.29 11.4 5.2 0.32 11.3 0.0 2.6 2 2 1 3 3 3 0 AAA domain AAA_10 PF12846.2 EAU93483.1 - 0.35 10.2 0.1 0.35 10.2 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain OmpH PF03938.9 EAU93483.1 - 3.4 7.5 6.1 7.2 6.5 4.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MMR_HSR1 PF01926.18 EAU93484.2 - 5.5e-10 39.2 0.0 8.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU93484.2 - 1.4e-07 31.4 0.1 0.0032 17.3 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EAU93484.2 - 6.7e-07 28.6 0.0 8.7e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 EAU93484.2 - 1.4e-05 24.3 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 EAU93484.2 - 0.00031 19.9 0.0 0.00059 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EAU93484.2 - 0.0097 16.3 0.0 0.028 14.9 0.0 1.7 1 1 1 2 2 2 1 Miro-like protein KaiC PF06745.8 EAU93484.2 - 0.013 14.6 0.1 0.027 13.5 0.1 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 EAU93484.2 - 0.044 14.0 0.0 0.076 13.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter GBP PF02263.14 EAU93484.2 - 0.053 12.5 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain IIGP PF05049.8 EAU93484.2 - 0.079 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.5 EAU93484.2 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 EAU93484.2 - 0.12 11.8 0.1 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Spore_IV_A PF09547.5 EAU93484.2 - 0.12 11.0 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) MMR_HSR1 PF01926.18 EAU93485.2 - 3.7e-09 36.5 0.0 9.7e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU93485.2 - 6.5e-06 25.4 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 EAU93485.2 - 3.2e-05 23.1 0.0 5.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 EAU93485.2 - 6.4e-05 22.8 0.0 0.65 9.8 0.0 2.9 3 1 0 3 3 3 2 Dynamin family DUF258 PF03193.11 EAU93485.2 - 0.00013 21.1 0.0 0.00079 18.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EAU93485.2 - 0.00043 19.1 0.0 0.00064 18.6 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EAU93485.2 - 0.0013 19.0 0.1 0.0035 17.6 0.0 1.8 2 1 0 2 2 2 1 ABC transporter KAP_NTPase PF07693.9 EAU93485.2 - 0.0097 14.9 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain Gtr1_RagA PF04670.7 EAU93485.2 - 0.023 13.8 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 EAU93485.2 - 0.031 13.7 0.4 0.14 11.5 0.3 2.0 1 1 0 1 1 1 0 AAA-like domain Spore_IV_A PF09547.5 EAU93485.2 - 0.037 12.7 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_29 PF13555.1 EAU93485.2 - 0.042 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EAU93485.2 - 0.045 13.7 0.1 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain GBP PF02263.14 EAU93485.2 - 0.05 12.6 0.0 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain T2SE PF00437.15 EAU93485.2 - 0.054 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SRPRB PF09439.5 EAU93485.2 - 0.06 12.5 0.0 0.099 11.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EAU93485.2 - 0.07 13.2 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EAU93485.2 - 0.1 13.1 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF87 PF01935.12 EAU93485.2 - 0.1 12.3 0.6 0.27 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 Sigma54_activat PF00158.21 EAU93485.2 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 EAU93485.2 - 0.38 11.0 3.9 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain FlxA PF14282.1 EAU93485.2 - 2 8.3 4.3 13 5.7 3.0 2.1 1 1 0 1 1 1 0 FlxA-like protein MMR_HSR1 PF01926.18 EAU93486.2 - 4.1e-12 46.0 1.1 6.1e-07 29.3 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EAU93486.2 - 2.2e-08 34.1 5.1 0.036 13.8 0.0 4.2 4 0 0 4 4 4 2 Dynamin family DUF258 PF03193.11 EAU93486.2 - 1.4e-07 30.8 0.4 0.0021 17.2 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function, DUF258 Septin PF00735.13 EAU93486.2 - 6.3e-06 25.4 0.1 0.00043 19.3 0.0 2.2 2 0 0 2 2 2 1 Septin ABC_tran PF00005.22 EAU93486.2 - 1.8e-05 25.0 0.0 0.0034 17.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 EAU93486.2 - 1.9e-05 23.8 4.7 0.0051 15.9 0.0 3.5 4 0 0 4 4 4 2 AIG1 family AAA_29 PF13555.1 EAU93486.2 - 3.2e-05 23.3 0.0 0.11 12.0 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EAU93486.2 - 8.6e-05 22.0 0.5 0.11 11.9 0.0 3.6 3 2 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 EAU93486.2 - 0.00094 19.5 0.2 0.015 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EAU93486.2 - 0.0013 18.9 0.0 0.23 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EAU93486.2 - 0.0014 18.6 0.0 0.14 12.1 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain T2SE PF00437.15 EAU93486.2 - 0.0015 17.4 0.0 0.083 11.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Adeno_IVa2 PF02456.10 EAU93486.2 - 0.0081 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_30 PF13604.1 EAU93486.2 - 0.01 15.4 0.6 8.8 5.8 0.0 3.2 2 1 1 3 3 3 0 AAA domain NB-ARC PF00931.17 EAU93486.2 - 0.011 14.6 0.1 0.079 11.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 EAU93486.2 - 0.011 14.8 0.3 1.6 7.7 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.1 EAU93486.2 - 0.012 15.8 0.9 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EAU93486.2 - 0.015 14.7 4.0 1.6 8.0 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain Sigma54_activat PF00158.21 EAU93486.2 - 0.1 12.0 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EAU93486.2 - 0.13 11.7 0.4 0.65 9.3 0.0 2.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.1 EAU93486.2 - 0.16 11.8 0.6 21 4.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 EAU93486.2 - 0.21 10.3 0.5 0.67 8.7 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 EAU93486.2 - 0.39 11.5 11.5 0.38 11.5 0.5 2.9 3 1 0 3 3 2 0 AAA domain SRP54 PF00448.17 EAU93486.2 - 0.96 8.8 4.5 29 4.0 0.2 3.6 2 2 1 4 4 4 0 SRP54-type protein, GTPase domain AAA PF00004.24 EAU93486.2 - 2.8 8.1 5.1 0.53 10.4 0.2 2.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EAU93487.1 - 1.9e-10 40.6 0.0 3.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EAU93487.1 - 1.8e-09 37.0 0.0 3e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EAU93487.1 - 7.6e-07 29.0 0.1 0.007 16.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 EAU93487.1 - 1.7e-06 27.2 0.0 4e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EAU93487.1 - 5.4e-05 23.6 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EAU93487.1 - 0.00012 21.2 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Septin IIGP PF05049.8 EAU93487.1 - 0.00019 20.3 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EAU93487.1 - 0.00032 21.0 0.0 0.00068 19.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EAU93487.1 - 0.0069 16.5 0.0 0.06 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EAU93487.1 - 0.012 15.7 0.0 0.051 13.7 0.0 2.0 1 1 0 2 2 2 0 RNA helicase Gtr1_RagA PF04670.7 EAU93487.1 - 0.048 12.7 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 EAU93487.1 - 0.066 12.6 0.1 0.18 11.2 0.0 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EAU93487.1 - 0.082 12.3 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EAU93487.1 - 0.083 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EAU93487.1 - 0.093 11.6 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-C2H2_jaz PF12171.3 EAU93488.2 - 2.1e-23 81.7 32.3 7.5e-07 29.1 0.2 6.9 7 0 0 7 7 7 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU93488.2 - 2.2e-22 78.4 33.6 0.00021 21.3 0.1 7.2 7 0 0 7 7 7 6 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EAU93488.2 - 3.5e-16 58.4 36.8 0.00049 20.2 0.1 7.6 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EAU93488.2 - 2e-14 52.9 25.6 0.0093 15.8 0.1 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EAU93488.2 - 8.8e-14 50.7 32.2 0.01 16.1 0.1 7.6 7 0 0 7 7 7 7 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EAU93488.2 - 6.6e-05 23.0 31.0 0.66 10.3 0.2 7.5 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_2 PF12756.2 EAU93488.2 - 0.0015 18.5 31.5 0.042 13.9 0.4 6.3 2 2 5 7 7 7 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EAU93488.2 - 0.51 10.0 14.2 2 8.1 0.0 5.4 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Acetyltransf_7 PF13508.1 EAU93492.1 - 0.0035 17.4 0.0 0.012 15.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4574 PF15141.1 EAU93492.1 - 0.055 13.2 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) Acetyltransf_9 PF13527.1 EAU93492.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.17 EAU93493.2 - 1.5e-05 24.3 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EAU93493.2 - 0.056 13.3 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 EAU93494.2 - 4.1e-181 581.2 66.6 6.5e-14 51.1 0.2 20.7 21 0 0 21 21 21 20 WD domain, G-beta repeat NACHT PF05729.7 EAU93494.2 - 2.6e-08 33.7 0.0 4.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EAU93494.2 - 7.1e-08 31.9 3.7 81 3.0 0.0 9.1 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EAU93494.2 - 3.7e-06 27.0 0.2 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Nbas_N PF15492.1 EAU93494.2 - 0.0032 16.6 9.1 14 4.6 0.0 7.5 7 2 2 9 9 9 1 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.1 EAU93494.2 - 0.053 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EAU93494.2 - 0.071 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Arch_ATPase PF01637.13 EAU93494.2 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 EAU93494.2 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF4208 PF13907.1 EAU93494.2 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Peptidase_S10 PF00450.17 EAU93495.1 - 7e-103 344.9 0.0 8.9e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EAU93495.1 - 1e-05 25.5 0.0 0.00023 21.1 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Pox_A9 PF04835.7 EAU93495.1 - 0.13 12.2 1.8 0.16 11.9 0.0 2.0 3 0 0 3 3 3 0 A9 protein conserved region Abhydrolase_1 PF00561.15 EAU93496.1 - 4e-37 127.9 0.0 8.2e-37 126.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EAU93496.1 - 4e-11 43.2 0.5 2.3e-10 40.7 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EAU93496.1 - 0.003 17.4 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein p450 PF00067.17 EAU93497.1 - 8.3e-80 268.5 0.0 9.7e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.11 EAU93499.2 - 5.1e-140 466.1 11.6 6.2e-140 465.8 8.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase AAA_33 PF13671.1 EAU93500.2 - 0.0071 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EAU93500.2 - 0.022 15.2 0.0 0.036 14.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 EAU93500.2 - 0.073 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.18 EAU93500.2 - 0.11 12.4 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EAU93500.2 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aminotran_4 PF01063.14 EAU93503.2 - 1.1e-20 74.0 0.0 2.1e-20 73.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV NUDIX PF00293.23 EAU93504.2 - 1.2e-05 24.9 0.0 3.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain CSTF2_hinge PF14327.1 EAU93504.2 - 0.0093 16.0 0.9 0.017 15.1 0.2 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 TMEM154 PF15102.1 EAU93510.2 - 0.00023 20.9 1.9 0.00044 19.9 1.3 1.3 1 0 0 1 1 1 1 TMEM154 protein family GRP PF07172.6 EAU93510.2 - 0.001 19.5 3.6 0.001 19.5 2.5 2.6 2 0 0 2 2 2 1 Glycine rich protein family Herpes_gE PF02480.11 EAU93510.2 - 0.018 13.3 0.1 0.029 12.6 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E gpUL132 PF11359.3 EAU93510.2 - 0.024 13.9 1.2 0.048 12.9 0.8 1.4 1 0 0 1 1 1 0 Glycoprotein UL132 SSP160 PF06933.6 EAU93510.2 - 0.12 10.3 7.8 0.18 9.7 5.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PAT1 PF09770.4 EAU93510.2 - 2.5 6.2 5.6 3.7 5.6 3.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tyrosinase PF00264.15 EAU93514.2 - 3e-39 135.4 0.0 4.2e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Fumarate_red_D PF02313.12 EAU93515.1 - 0.00017 21.4 0.0 2.4 8.0 0.0 3.2 3 0 0 3 3 3 3 Fumarate reductase subunit D Ribonuc_L-PSP PF01042.16 EAU93517.1 - 2.4e-20 72.5 0.0 2.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP NP1-WLL PF11733.3 EAU93518.2 - 0.07 13.4 0.5 0.14 12.3 0.3 1.5 1 0 0 1 1 1 0 Non-capsid protein NP1 DUF2457 PF10446.4 EAU93519.1 - 2.4 6.7 9.7 4.7 5.8 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-MYND PF01753.13 EAU93520.2 - 2.4e-10 40.1 8.0 4.8e-10 39.1 5.6 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EAU93520.2 - 0.017 14.4 2.1 0.048 12.9 1.4 1.7 1 0 0 1 1 1 0 Life-span regulatory factor zf-Mss51 PF13824.1 EAU93520.2 - 0.12 12.3 4.2 0.25 11.2 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4449 PF14613.1 EAU93522.1 - 3.8e-22 78.9 1.0 3.8e-22 78.9 0.7 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) MitMem_reg PF13012.1 EAU93522.1 - 0.022 14.8 0.9 0.048 13.7 0.0 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function SNN_cytoplasm PF09051.5 EAU93524.1 - 0.057 13.1 3.2 1.3 8.8 0.1 3.0 3 0 0 3 3 3 0 Stannin cytoplasmic DUF1491 PF07372.7 EAU93527.1 - 0.018 14.9 0.0 0.28 11.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1491) Staph_haemo PF05480.6 EAU93527.1 - 0.11 12.2 2.4 5.3 6.8 0.2 2.4 2 0 0 2 2 2 0 Staphylococcus haemolytic protein Tyrosinase PF00264.15 EAU93528.2 - 1.1e-38 133.6 0.0 1.4e-38 133.2 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Spc7_N PF15402.1 EAU93529.2 - 1.1 7.1 5.0 1.5 6.7 3.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PP2C PF00481.16 EAU93530.2 - 1.5e-18 67.1 0.0 4.7e-12 45.8 0.0 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.7 EAU93530.2 - 0.01 15.5 0.0 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF1390 PF07150.6 EAU93531.1 - 0.064 12.6 1.7 0.072 12.4 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) PP_M1 PF03012.9 EAU93531.1 - 0.24 10.7 1.1 7.2 5.8 0.2 2.0 2 0 0 2 2 2 0 Phosphoprotein P68HR PF08061.6 EAU93532.1 - 0.083 12.6 0.2 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 P68HR (NUC004) repeat DUF1470 PF07336.6 EAU93536.2 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) Metalloenzyme PF01676.13 EAU93538.2 - 3.8e-77 259.0 0.0 8.1e-77 257.9 0.0 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EAU93538.2 - 1.4e-70 237.1 0.0 6e-70 235.0 0.0 1.9 1 1 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EAU93538.2 - 5.7e-08 32.4 0.0 9.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EAU93538.2 - 8.8e-06 25.1 0.1 3.6e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 EAU93538.2 - 0.011 14.4 0.2 0.029 13.0 0.1 1.7 2 0 0 2 2 2 0 Alkaline phosphatase PglZ PF08665.7 EAU93538.2 - 0.031 13.9 0.1 0.078 12.6 0.1 1.6 2 0 0 2 2 2 0 PglZ domain Methyltransf_31 PF13847.1 EAU93538.2 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HALZ PF02183.13 EAU93540.2 - 0.0021 17.7 2.5 0.17 11.5 0.1 2.6 2 0 0 2 2 2 2 Homeobox associated leucine zipper Transposase_22 PF02994.9 EAU93540.2 - 0.0048 15.4 0.7 0.0091 14.5 0.5 1.4 1 0 0 1 1 1 1 L1 transposable element Spc7 PF08317.6 EAU93540.2 - 0.013 14.2 4.1 0.031 12.9 2.8 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.6 EAU93540.2 - 0.013 15.3 3.3 0.3 10.9 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.17 EAU93540.2 - 0.023 14.7 5.2 0.8 9.7 0.3 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Microtub_assoc PF07989.6 EAU93540.2 - 0.056 13.2 0.2 0.056 13.2 0.1 2.8 3 0 0 3 3 3 0 Microtubule associated DivIC PF04977.10 EAU93540.2 - 0.13 11.7 5.4 0.046 13.2 0.5 2.4 2 0 0 2 2 2 0 Septum formation initiator ATG16 PF08614.6 EAU93540.2 - 1.5 8.6 9.3 0.038 13.8 1.2 2.3 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) JmjN PF02375.12 EAU93541.2 - 0.11 12.0 0.4 0.26 10.8 0.3 1.7 1 0 0 1 1 1 0 jmjN domain DUF605 PF04652.11 EAU93543.2 - 9 5.5 27.5 14 4.9 19.1 1.2 1 0 0 1 1 1 0 Vta1 like GST_C_2 PF13410.1 EAU93547.2 - 0.076 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EAU93548.2 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like Rotavirus_VP7 PF05868.6 EAU93549.1 - 0.052 12.7 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 V-ATPase_G PF03179.10 EAU93549.1 - 0.076 13.3 5.3 0.099 12.9 3.7 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF4337 PF14235.1 EAU93549.1 - 0.49 10.2 5.1 0.72 9.6 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ATP_bind_2 PF03668.10 EAU93551.1 - 0.072 12.1 0.1 0.077 12.0 0.1 1.1 1 0 0 1 1 1 0 P-loop ATPase protein family F-box-like PF12937.2 EAU93552.1 - 0.0013 18.4 0.4 0.0058 16.3 0.2 2.3 1 1 0 1 1 1 1 F-box-like Pyrophosphatase PF00719.14 EAU93555.1 - 0.059 12.8 1.9 0.081 12.3 1.3 1.2 1 0 0 1 1 1 0 Inorganic pyrophosphatase DUF4337 PF14235.1 EAU93555.1 - 0.25 11.1 3.6 0.42 10.4 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Bap31 PF05529.7 EAU93555.1 - 0.59 9.5 2.8 0.81 9.1 1.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pyrophosphatase PF00719.14 EAU93556.2 - 0.027 13.9 1.7 0.036 13.5 1.2 1.2 1 0 0 1 1 1 0 Inorganic pyrophosphatase DUF4337 PF14235.1 EAU93556.2 - 0.092 12.5 2.6 0.12 12.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF342 PF03961.8 EAU93556.2 - 0.15 10.4 0.7 0.17 10.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Bap31 PF05529.7 EAU93556.2 - 0.29 10.5 2.5 0.35 10.2 1.8 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like F-box PF00646.28 EAU93557.1 - 7.3e-06 25.5 0.0 1.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EAU93557.1 - 0.00031 20.4 0.0 0.00071 19.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like ERCC4 PF02732.10 EAU93561.2 - 2e-09 37.3 0.0 0.0018 18.0 0.0 2.9 1 1 1 2 2 2 2 ERCC4 domain DUF4456 PF14644.1 EAU93562.2 - 0.064 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) F-box-like PF12937.2 EAU93564.1 - 4e-07 29.6 0.2 9.6e-07 28.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EAU93564.1 - 7.9e-06 25.3 1.5 5.3e-05 22.7 0.1 2.7 2 0 0 2 2 2 1 F-box domain DUF1814 PF08843.6 EAU93569.1 - 0.00059 19.7 0.1 0.00075 19.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF21 PF01595.15 EAU93571.2 - 1.3e-24 86.5 0.5 1.9e-24 85.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EAU93571.2 - 7.3e-07 28.8 0.0 0.094 12.5 0.0 3.4 3 0 0 3 3 3 2 CBS domain DUF4401 PF14351.1 EAU93571.2 - 0.0088 15.0 5.8 0.013 14.4 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) F-box-like PF12937.2 EAU93572.1 - 1.1e-07 31.4 0.6 2.9e-07 30.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like CHAT PF12770.2 EAU93574.2 - 4.6e-30 104.7 0.0 2.8e-29 102.1 0.0 2.1 2 0 0 2 2 2 1 CHAT domain TPR_12 PF13424.1 EAU93574.2 - 8.8e-21 73.6 6.4 0.046 13.6 0.0 9.5 5 2 3 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.1 EAU93574.2 - 4.3e-06 26.4 13.7 0.44 10.5 0.0 9.4 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EAU93574.2 - 0.00022 20.8 5.2 0.43 10.4 0.0 7.3 10 0 0 10 10 10 1 Tetratricopeptide repeat FolB PF02152.13 EAU93574.2 - 0.079 13.1 0.0 0.69 10.0 0.0 2.6 2 1 1 3 3 3 0 Dihydroneopterin aldolase Sel1 PF08238.7 EAU93574.2 - 0.15 12.7 0.1 3.9 8.2 0.1 3.2 3 0 0 3 3 3 0 Sel1 repeat MIT PF04212.13 EAU93574.2 - 0.21 11.4 1.0 16 5.4 0.0 3.5 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain AAA PF00004.24 EAU93575.1 - 6.4e-15 55.5 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EAU93575.1 - 0.0046 17.2 0.0 0.23 11.7 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EAU93575.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EAU93575.1 - 0.0067 16.5 0.6 0.19 11.8 0.0 2.7 1 1 1 2 2 2 1 AAA domain FTZ PF03867.9 EAU93575.1 - 0.019 14.2 0.3 0.039 13.2 0.2 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region AAA_17 PF13207.1 EAU93575.1 - 0.049 14.4 0.0 0.22 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EAU93575.1 - 0.059 13.3 0.3 0.38 10.7 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain RD3 PF14473.1 EAU93576.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 RD3 protein DUF3603 PF12227.3 EAU93576.1 - 0.15 11.1 0.0 0.39 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) DUF3967 PF13152.1 EAU93576.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3967) Pkinase PF00069.20 EAU93577.2 - 3.2e-53 180.5 5.9 1e-27 96.9 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.2 EAU93577.2 - 6.4e-26 91.1 0.0 6.4e-26 91.1 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 EAU93577.2 - 1e-25 90.3 0.1 2.1e-08 33.5 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EAU93577.2 - 6.9e-16 58.1 0.1 2.2e-15 56.5 0.1 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EAU93577.2 - 4.5e-09 35.7 0.0 1.2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Toxin_43 PF15604.1 EAU93577.2 - 1.9 8.5 9.6 4.2 7.4 0.0 2.8 2 0 0 2 2 2 0 Putative toxin 43 ChaC PF04752.7 EAU93578.2 - 1.2e-37 129.6 0.0 3.7e-32 111.6 0.0 2.0 1 1 1 2 2 2 2 ChaC-like protein tRNA_U5-meth_tr PF05958.6 EAU93579.1 - 2.6e-18 65.8 0.0 3e-17 62.3 0.0 2.6 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 EAU93579.1 - 6.4e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 EAU93579.1 - 7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EAU93579.1 - 4.3e-05 22.9 0.0 8.7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 EAU93579.1 - 7.1e-05 23.3 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EAU93579.1 - 0.0034 16.9 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 EAU93579.1 - 0.042 12.9 0.1 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NADH_dh_m_C1 PF15088.1 EAU93579.1 - 0.072 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DLH PF01738.13 EAU93580.2 - 1.5e-20 73.4 0.0 1.8e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU93580.2 - 7.7e-08 32.2 0.0 9.5e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU93580.2 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EAU93580.2 - 0.0053 16.6 0.1 0.21 11.4 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU93580.2 - 0.0074 15.8 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EAU93581.2 - 3.9e-24 85.1 0.0 4.4e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EAU93581.2 - 4.5e-09 36.1 0.0 6.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EAU93581.2 - 0.00048 20.0 0.3 0.36 10.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EAU93581.2 - 0.0024 17.1 0.1 0.0048 16.1 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EAU93581.2 - 0.003 17.1 0.0 0.17 11.4 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2607 PF10795.4 EAU93581.2 - 0.15 11.9 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Pkinase PF00069.20 EAU93582.1 - 1.1e-61 208.2 0.0 1.5e-61 207.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EAU93582.1 - 1.6e-28 99.5 0.0 2.1e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EAU93582.1 - 1.9e-07 30.3 0.0 5.9e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EAU93582.1 - 0.041 13.6 0.1 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EAU93582.1 - 0.07 12.1 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 EAU93583.2 - 2.2e-69 234.1 0.1 1.4e-68 231.4 0.1 2.0 1 1 0 1 1 1 1 Cytochrome P450 4HBT PF03061.17 EAU93587.1 - 4.8e-11 42.6 0.0 7.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily CHAT PF12770.2 EAU93588.2 - 8.5e-29 100.5 0.0 1.8e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EAU93588.2 - 1.6e-20 72.8 15.8 0.02 14.7 0.0 12.3 8 3 5 14 14 14 6 Tetratricopeptide repeat TPR_11 PF13414.1 EAU93588.2 - 1.3e-12 47.1 22.9 0.012 15.2 0.0 11.7 4 3 8 14 14 14 5 TPR repeat TPR_17 PF13431.1 EAU93588.2 - 1.4e-09 37.4 3.4 12 6.4 0.0 11.4 14 0 0 14 14 14 1 Tetratricopeptide repeat Sel1 PF08238.7 EAU93588.2 - 0.1 13.2 0.0 42 4.9 0.0 4.2 4 0 0 4 4 4 0 Sel1 repeat Methyltransf_16 PF10294.4 EAU93589.2 - 4.2e-14 52.3 0.0 6.9e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EAU93589.2 - 6e-05 23.5 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EAU93589.2 - 0.0027 17.6 0.0 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EAU93589.2 - 0.0053 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EAU93589.2 - 0.039 13.5 0.0 0.087 12.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EAU93589.2 - 0.15 11.3 0.4 1.4 8.2 0.1 2.4 2 1 1 3 3 3 0 Methyltransferase small domain TPR_11 PF13414.1 EAU93591.1 - 5.7e-12 45.1 0.3 4.6e-05 22.9 0.0 3.8 2 2 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EAU93591.1 - 1.5e-10 40.1 0.5 0.011 15.3 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EAU93591.1 - 4e-10 38.8 0.1 0.069 13.0 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EAU93591.1 - 1.3e-07 31.3 3.4 0.0019 18.0 0.1 4.3 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EAU93591.1 - 3.6e-07 30.2 2.6 5.8 7.8 0.0 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EAU93591.1 - 1.5e-05 24.4 3.5 5.1 7.1 0.0 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EAU93591.1 - 3.4e-05 23.3 0.0 7.5 6.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EAU93591.1 - 0.00082 19.9 4.4 0.73 10.5 0.1 4.2 2 1 4 6 6 6 3 Tetratricopeptide repeat MIT PF04212.13 EAU93591.1 - 0.00096 18.9 0.0 0.75 9.7 0.0 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 EAU93591.1 - 0.0022 18.3 0.4 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M43 PF05572.8 EAU93594.2 - 3.9e-11 42.7 0.0 7.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EAU93594.2 - 0.041 13.8 0.0 0.093 12.6 0.0 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EAU93594.2 - 0.32 11.5 3.3 3.4 8.2 1.1 2.6 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.8 EAU93595.1 - 8.8e-14 51.3 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EAU93595.1 - 3.7e-06 27.4 0.1 7.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EAU93595.1 - 2.5e-05 24.4 0.0 4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EAU93595.1 - 8e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EAU93595.1 - 0.012 15.1 0.3 0.032 13.7 0.2 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EAU93595.1 - 0.043 13.5 0.9 0.1 12.2 0.6 1.8 1 1 0 1 1 1 0 Matrixin CDC27 PF09507.5 EAU93596.1 - 0.092 11.9 43.5 0.13 11.4 30.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 EAU93596.1 - 0.45 8.9 34.3 0.57 8.6 23.8 1.2 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 EAU93596.1 - 2.9 5.9 42.8 3.7 5.5 29.7 1.0 1 0 0 1 1 1 0 Utp14 protein DUF605 PF04652.11 EAU93596.1 - 5.2 6.3 28.7 0.28 10.5 10.9 2.1 1 1 0 2 2 2 0 Vta1 like zf-LITAF-like PF10601.4 EAU93598.1 - 7e-05 22.6 0.2 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zinc_ribbon_5 PF13719.1 EAU93598.1 - 0.16 11.5 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain zf-LITAF-like PF10601.4 EAU93599.2 - 0.00073 19.3 0.1 0.0011 18.7 0.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DUF2348 PF09807.4 EAU93602.2 - 1.8e-06 27.2 0.0 1.9e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Ribosomal_L7Ae PF01248.21 EAU93603.2 - 3e-21 74.7 0.8 5.6e-21 73.8 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Metallophos PF00149.23 EAU93605.2 - 3e-10 39.8 1.4 5.7e-10 38.9 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.2 EAU93606.1 - 2.8e-12 46.1 1.0 6.9e-12 44.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EAU93606.1 - 0.31 10.7 2.6 1 9.1 0.1 3.3 3 1 0 3 3 3 0 F-box domain Alpha-amylase PF00128.19 EAU93608.2 - 9.7e-101 337.2 0.3 1.7e-100 336.4 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DSPc PF00782.15 EAU93609.1 - 6e-07 29.1 0.0 8.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EAU93609.1 - 1.9e-05 24.7 0.1 5.5e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate CDKN3 PF05706.7 EAU93609.1 - 0.0017 17.8 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 EAU93609.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EAU93609.1 - 0.0063 16.7 0.2 0.81 9.9 0.1 2.2 1 1 1 2 2 2 2 Tyrosine phosphatase family Cullin PF00888.17 EAU93610.2 - 2.7e-44 151.7 0.0 4.1e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EAU93610.2 - 1.5e-09 37.9 0.0 6.7e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 GST_N_3 PF13417.1 EAU93612.1 - 5.4e-12 45.7 0.0 2e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EAU93612.1 - 4.1e-10 39.5 0.0 8.5e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EAU93612.1 - 4.1e-05 24.0 0.2 0.00011 22.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EAU93612.1 - 0.00016 21.5 0.0 0.00047 19.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EAU93612.1 - 0.00046 20.1 0.1 0.001 18.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EAU93612.1 - 0.048 13.8 0.0 0.3 11.3 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain peroxidase PF00141.18 EAU93612.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Peroxidase p450 PF00067.17 EAU93613.1 - 1.4e-76 257.8 0.0 1.6e-76 257.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3039 PF11238.3 EAU93613.1 - 0.12 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) F-box-like PF12937.2 EAU93614.2 - 1e-09 37.9 0.4 7.5e-09 35.1 0.0 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EAU93614.2 - 0.022 14.3 0.3 0.11 12.2 0.1 2.2 2 0 0 2 2 2 0 F-box domain Metallophos PF00149.23 EAU93615.2 - 3.1e-08 33.2 2.2 4.8e-05 22.8 0.1 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Peptidase_C14 PF00656.17 EAU93616.2 - 3.6e-52 177.5 0.0 5.9e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.13 EAU93616.2 - 0.075 12.3 0.1 2.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Peptidase C13 family SOG2 PF10428.4 EAU93616.2 - 8.3 4.9 18.9 12 4.4 13.1 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase_Tyr PF07714.12 EAU93617.2 - 3.8e-25 88.4 0.0 4.7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EAU93617.2 - 1.3e-21 76.8 0.0 1.8e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain AAA_17 PF13207.1 EAU93618.1 - 4.4e-06 27.5 0.0 1.2e-05 26.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EAU93618.1 - 0.00012 22.0 0.2 0.0016 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EAU93618.1 - 0.00035 20.8 0.1 0.0011 19.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EAU93618.1 - 0.00084 18.9 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 EAU93618.1 - 0.0078 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 ArgK protein KTI12 PF08433.5 EAU93618.1 - 0.019 14.1 0.0 0.036 13.2 0.0 1.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 OapA_N PF08525.6 EAU93618.1 - 0.023 14.4 0.1 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif AAA_14 PF13173.1 EAU93618.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EAU93618.1 - 0.15 11.1 0.1 0.32 10.0 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin zf-C2H2 PF00096.21 EAU93620.2 - 3.5e-10 39.6 9.7 6.2e-05 23.0 0.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EAU93620.2 - 2.9e-09 36.7 7.3 9.9e-07 28.7 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EAU93620.2 - 1.8e-07 31.0 8.5 0.0014 18.8 2.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EAU93620.2 - 6.8e-05 22.8 0.7 0.47 10.6 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EAU93620.2 - 0.0015 18.6 1.8 0.15 12.2 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EAU93620.2 - 0.0068 16.0 1.6 0.0068 16.0 1.1 2.7 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-CHY PF05495.7 EAU93620.2 - 0.026 14.6 1.9 0.043 13.9 1.3 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-BED PF02892.10 EAU93620.2 - 0.11 12.2 8.7 2.6 7.8 0.4 2.4 1 1 1 2 2 2 0 BED zinc finger RRN7 PF11781.3 EAU93620.2 - 0.15 11.5 0.8 3.4 7.2 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_2 PF12756.2 EAU93620.2 - 0.4 10.8 3.2 2.6 8.1 0.7 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Bromodomain PF00439.20 EAU93621.2 - 1.2e-21 76.3 0.4 1.1e-16 60.5 0.0 2.9 3 0 0 3 3 3 2 Bromodomain BAH PF01426.13 EAU93621.2 - 2.3e-09 37.0 0.0 4.7e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 BAH domain A_deaminase PF00962.17 EAU93623.1 - 5.2e-22 78.2 0.0 6.5e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase MGC-24 PF05283.6 EAU93624.1 - 0.19 11.4 0.1 0.19 11.4 0.0 3.5 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24) Beta_helix PF13229.1 EAU93625.1 - 2.9e-06 27.1 22.0 6.6e-05 22.7 11.3 3.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 EAU93625.1 - 0.00065 18.9 6.4 0.044 12.9 4.2 2.2 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) SKG6 PF08693.5 EAU93625.1 - 0.0074 15.5 0.7 0.019 14.2 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EAU93625.1 - 0.17 11.4 1.5 0.29 10.6 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Arm PF00514.18 EAU93626.2 - 6.8e-06 25.7 15.2 0.32 10.8 0.2 7.7 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EAU93626.2 - 7.8e-05 22.8 15.5 0.71 10.1 0.3 6.3 4 2 2 6 6 6 4 HEAT repeats Ric8 PF10165.4 EAU93626.2 - 0.0014 17.5 0.0 0.017 13.9 0.0 2.6 4 0 0 4 4 4 1 Guanine nucleotide exchange factor synembryn DUF3636 PF12331.3 EAU93626.2 - 0.026 14.1 0.0 0.45 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) ImpE PF07024.8 EAU93628.2 - 0.068 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 ImpE protein Cellulase PF00150.13 EAU93630.1 - 1.1e-14 54.3 0.0 1.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EAU93630.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 2 0 0 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EAU93630.1 - 0.0025 16.9 0.0 0.012 14.7 0.0 2.0 1 1 0 1 1 1 1 Beta-galactosidase DUF973 PF06157.6 EAU93633.1 - 0.027 13.4 0.7 0.027 13.4 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Aminotran_1_2 PF00155.16 EAU93634.2 - 6.8e-16 58.1 0.0 9.1e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EAU93638.1 - 0.051 12.5 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Abhydrolase_6 PF12697.2 EAU93639.1 - 2.7e-22 79.7 0.0 3.4e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EAU93639.1 - 1.3e-09 37.9 0.0 0.0014 18.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EAU93639.1 - 9.4e-09 35.1 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EAU93639.1 - 0.0025 17.6 0.0 0.0047 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase AMP-binding PF00501.23 EAU93640.1 - 5.2e-32 110.7 0.0 6.8e-30 103.7 0.0 2.8 3 0 0 3 3 3 3 AMP-binding enzyme PS_Dcarbxylase PF02666.10 EAU93641.1 - 9.7e-73 243.7 0.0 2.7e-71 239.0 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase WD40 PF00400.27 EAU93642.2 - 1.1e-12 47.2 15.6 1.4e-05 24.7 0.3 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Menin PF05053.8 EAU93642.2 - 1.8 6.6 3.4 2.9 5.9 2.3 1.2 1 0 0 1 1 1 0 Menin DUF1793 PF08760.6 EAU93643.2 - 0.00038 20.3 0.2 0.0011 18.8 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1793) SKG6 PF08693.5 EAU93643.2 - 0.057 12.7 0.5 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GD_AH_C PF04295.8 EAU93643.2 - 0.086 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus AMP-binding PF00501.23 EAU93644.2 - 0.0012 17.3 0.0 0.0012 17.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme G-alpha PF00503.15 EAU93646.2 - 1e-106 356.9 0.1 1.2e-106 356.6 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EAU93646.2 - 7.9e-12 44.7 3.3 2e-07 30.3 0.4 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EAU93646.2 - 0.00084 19.8 0.1 0.21 12.0 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein DUF2951 PF11166.3 EAU93646.2 - 0.029 14.2 0.5 0.077 12.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) MMR_HSR1 PF01926.18 EAU93646.2 - 0.034 14.0 0.0 7.1 6.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EAU93646.2 - 0.038 13.4 0.1 2.8 7.3 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EAU93646.2 - 0.039 13.4 0.2 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EAU93646.2 - 0.05 12.7 5.3 0.76 8.8 0.1 2.7 3 1 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EAU93646.2 - 0.052 13.0 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Tenui_N PF05733.6 EAU93646.2 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein Sigma54_activat PF00158.21 EAU93646.2 - 0.066 12.6 0.4 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.4 EAU93646.2 - 0.16 10.8 1.1 0.26 10.1 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Dimer_Tnp_hAT PF05699.9 EAU93647.2 - 5.7e-11 41.8 0.0 1.4e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EAU93647.2 - 0.047 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Med3 PF11593.3 EAU93647.2 - 7.2 5.7 8.0 13 4.8 5.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SR-25 PF10500.4 EAU93647.2 - 9.3 5.6 13.8 0.41 10.0 0.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein tRNA-synt_1c PF00749.16 EAU93648.2 - 6.9e-71 238.4 0.0 1.1e-70 237.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-UBR PF02207.15 EAU93649.2 - 4.1e-17 61.6 15.1 4.1e-17 61.6 10.4 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EAU93649.2 - 0.0074 15.9 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS UPF0300 PF08594.5 EAU93649.2 - 0.17 10.8 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) Alpha-amylase PF00128.19 EAU93650.1 - 2.5e-81 273.5 5.2 3.4e-80 269.7 1.2 2.6 2 1 0 2 2 2 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 EAU93650.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) p450 PF00067.17 EAU93651.2 - 9.3e-66 222.2 0.0 5.5e-50 170.2 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 SNF2_N PF00176.18 EAU93652.2 - 3.1e-22 78.7 0.1 4.7e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU93652.2 - 4.5e-13 48.8 0.0 1e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU93652.2 - 4.3e-06 26.6 0.0 1.4e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit LYTB PF02401.13 EAU93652.2 - 0.25 10.2 1.3 8.9 5.1 0.4 2.2 2 0 0 2 2 2 0 LytB protein SNF2_N PF00176.18 EAU93653.2 - 1.9e-27 95.8 0.1 3.1e-27 95.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EAU93653.2 - 6.9e-12 45.0 0.0 1.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EAU93653.2 - 3.9e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Abhydrolase_3 PF07859.8 EAU93656.1 - 2.5e-16 59.8 0.0 3.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EAU93656.1 - 1.7e-10 40.1 0.0 6e-10 38.2 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EAU93656.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family CHD5 PF04420.9 EAU93656.1 - 0.048 13.3 0.1 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 CHD5-like protein Cullin PF00888.17 EAU93657.2 - 6.8e-109 365.0 3.2 9.6e-109 364.5 2.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EAU93657.2 - 5.9e-22 77.2 1.2 5.9e-22 77.2 0.9 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_27 PF13463.1 EAU93657.2 - 0.07 13.4 0.2 32 4.9 0.0 3.2 3 0 0 3 3 3 0 Winged helix DNA-binding domain TPR_12 PF13424.1 EAU93658.2 - 3.9e-21 74.7 13.9 0.024 14.5 0.0 12.5 2 1 10 13 13 13 6 Tetratricopeptide repeat TPR_11 PF13414.1 EAU93658.2 - 2.3e-18 65.5 13.1 0.011 15.3 0.1 9.9 5 3 8 13 13 13 7 TPR repeat TPR_17 PF13431.1 EAU93658.2 - 4e-07 29.7 4.8 4.9 7.6 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 EAU93658.2 - 0.00011 21.7 5.4 91 3.3 0.0 8.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.1 EAU93658.2 - 0.00014 21.6 45.2 0.034 14.0 0.1 12.1 12 3 0 12 12 12 3 Tetratricopeptide repeat Syntaxin-6_N PF09177.6 EAU93658.2 - 0.0016 18.8 0.5 5.9 7.3 0.0 4.6 4 1 0 4 4 4 1 Syntaxin 6, N-terminal TPR_14 PF13428.1 EAU93658.2 - 0.54 11.0 12.0 21 6.1 0.0 7.3 6 2 3 9 9 9 0 Tetratricopeptide repeat Syntaxin-6_N PF09177.6 EAU93665.1 - 0.67 10.4 0.1 0.67 10.4 0.0 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal AT_hook PF02178.14 EAU93667.2 - 0.0012 18.3 0.7 0.0036 16.7 0.5 1.9 1 0 0 1 1 1 1 AT hook motif MSSP PF03940.8 EAU93675.1 - 0.064 12.6 8.5 0.13 11.6 5.9 1.4 1 0 0 1 1 1 0 Male specific sperm protein SBP_bac_7 PF03480.8 EAU93676.2 - 0.046 12.8 2.3 0.088 11.8 1.6 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Occludin_ELL PF07303.8 EAU93676.2 - 0.13 13.0 4.1 6.4 7.5 0.0 2.8 2 0 0 2 2 2 0 Occludin homology domain Phe_tRNA-synt_N PF02912.13 EAU93676.2 - 0.34 10.6 3.0 7.7 6.3 0.1 2.9 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain HA PF03457.9 EAU93676.2 - 0.48 10.5 7.6 0.19 11.8 0.5 3.3 3 0 0 3 3 3 0 Helicase associated domain DivIC PF04977.10 EAU93676.2 - 0.66 9.4 3.6 0.35 10.3 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator LPP PF04728.8 EAU93676.2 - 2.4 7.9 5.9 2.3 8.0 0.6 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper F-box-like PF12937.2 EAU93679.2 - 0.0057 16.3 0.2 0.023 14.4 0.0 2.2 2 1 0 2 2 2 1 F-box-like TAF4 PF05236.9 EAU93679.2 - 0.26 10.5 4.2 0.69 9.1 2.9 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BTB PF00651.26 EAU93681.1 - 0.0066 16.4 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain zf-MYND PF01753.13 EAU93684.2 - 5.9e-08 32.4 9.0 5.9e-08 32.4 6.2 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EAU93684.2 - 6.9 6.4 10.4 1.6 8.4 4.5 2.0 2 0 0 2 2 2 0 HIT zinc finger PRY PF13765.1 EAU93686.2 - 0.049 13.1 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 SPRY-associated domain MFS_1 PF07690.11 EAU93687.1 - 8.4e-18 64.2 45.2 1.1e-11 44.0 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EAU93687.1 - 0.0001 21.0 16.8 0.0001 21.0 11.7 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Peptidase_C48 PF02902.14 EAU93688.2 - 1.2e-05 25.1 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SBP_bac_7 PF03480.8 EAU93688.2 - 0.09 11.8 2.2 0.16 11.0 1.5 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 HA PF03457.9 EAU93688.2 - 2.4 8.3 7.5 0.43 10.7 0.5 3.0 2 0 0 2 2 2 0 Helicase associated domain ODR4-like PF14778.1 EAU93690.2 - 0.24 10.0 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 Olfactory receptor 4-like NADHdh PF00146.16 EFI26508.1 - 5.4e-112 373.8 24.7 6.6e-112 373.5 17.1 1.0 1 0 0 1 1 1 1 NADH dehydrogenase Oxidored_q1 PF00361.15 EFI26509.1 - 2.6e-65 220.4 19.9 2.6e-65 220.4 13.8 3.5 2 1 1 3 3 3 1 NADH-Ubiquinone/plastoquinone (complex I), various chains NADH5_C PF06455.6 EFI26509.1 - 4.2e-14 52.3 31.6 3.2e-08 33.1 6.2 5.1 3 2 0 4 4 4 2 NADH dehydrogenase subunit 5 C-terminus Oxidored_q1_C PF01010.14 EFI26509.1 - 7.2e-05 22.4 13.4 0.00014 21.4 9.3 1.4 1 0 0 1 1 1 1 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus DUF3995 PF13160.1 EFI26509.1 - 6.4 6.8 8.8 0.23 11.5 0.2 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3995) Oxidored_q2 PF00420.19 EFI26510.1 - 3.1e-21 74.7 12.0 3.3e-21 74.6 8.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4022 PF13214.1 EFI26510.1 - 0.047 13.7 9.0 0.081 13.0 6.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4022) DUF3098 PF11297.3 EFI26510.1 - 0.31 10.7 6.5 0.49 10.1 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) XK-related PF09815.4 EFI26510.1 - 0.37 9.7 4.2 0.42 9.5 2.9 1.1 1 0 0 1 1 1 0 XK-related protein DUF843 PF05814.6 EFI26510.1 - 2.8 7.7 9.4 4.1 7.2 6.5 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) SK_channel PF03530.9 EFI26510.1 - 5.7 6.7 7.2 10 6.0 4.9 1.5 1 1 0 1 1 1 0 Calcium-activated SK potassium channel Herpes_LMP1 PF05297.6 EFI26510.1 - 9.8 4.9 11.7 11 4.8 8.1 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ATP-synt_C PF00137.16 EFI26511.1 - 1.7e-19 69.4 13.0 1.9e-19 69.3 9.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit C Oxidored_q3 PF00499.15 EFI26512.1 - 2.8e-25 88.8 36.9 2.1e-24 85.9 25.6 2.0 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 NTPase_P4 PF11602.3 EFI26512.1 - 0.097 11.6 0.2 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 ATP-synt_A PF00119.15 EFI26513.1 - 2.5e-51 174.2 26.7 3.3e-51 173.8 18.5 1.1 1 0 0 1 1 1 1 ATP synthase A chain Cytochrom_B_N_2 PF13631.1 EFI26514.1 - 9.7e-43 145.8 19.8 4.9e-35 120.8 4.9 3.7 4 1 0 4 4 4 2 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.12 EFI26514.1 - 6.9e-41 138.6 3.2 6.9e-41 138.6 2.2 3.4 2 1 3 5 5 5 1 Cytochrome b(C-terminal)/b6/petD Cytochrom_B_N PF00033.14 EFI26514.1 - 2.8e-15 56.1 13.2 2.8e-15 56.1 9.1 2.8 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 EFI26514.1 - 5.6e-05 22.5 29.6 0.0024 17.2 2.3 3.3 2 1 1 3 3 3 3 Prokaryotic cytochrome b561 COX3 PF00510.13 EFI26515.1 - 6.2e-116 386.3 24.7 7.1e-116 386.1 17.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III Oxidored_q1 PF00361.15 EFI26516.1 - 6.9e-64 215.7 29.7 6.9e-64 215.7 20.6 3.3 3 1 1 4 4 4 1 NADH-Ubiquinone/plastoquinone (complex I), various chains COX1 PF00115.15 EFI26517.1 - 1.9e-172 573.9 51.0 2.4e-172 573.5 35.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I DNA_pol_B_2 PF03175.8 EFI26518.1 - 1.1e-58 199.0 50.4 8.1e-34 117.0 6.4 4.3 3 2 1 4 4 4 3 DNA polymerase type B, organellar and viral Oxidored_q4 PF00507.14 EFI26519.1 - 1.6e-22 79.2 8.6 2.3e-22 78.7 6.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF3671 PF12420.3 EFI26519.1 - 9 6.3 10.8 1.6 8.7 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function Oxidored_q1 PF00361.15 EFI26520.1 - 6.6e-55 186.2 39.9 1.6e-29 102.9 12.1 4.1 3 1 1 4 4 4 2 NADH-Ubiquinone/plastoquinone (complex I), various chains Fun_ATP-synt_8 PF05933.8 EFI26522.1 - 2.1e-17 62.8 13.7 2.3e-17 62.7 9.5 1.0 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) DUF1440 PF07274.7 EFI26522.1 - 0.22 11.5 1.5 0.23 11.4 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) ATP-synt_8 PF00895.15 EFI26522.1 - 2.1 8.6 6.1 2.9 8.1 4.3 1.5 1 1 0 1 1 1 0 ATP synthase protein 8 YMF19 PF02326.10 EFI26522.1 - 2.1 8.9 11.1 2.2 8.8 7.7 1.1 1 0 0 1 1 1 0 Plant ATP synthase F0 COX2 PF00116.15 EFI26523.1 - 1.1e-53 180.1 0.0 1.9e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.10 EFI26523.1 - 1.7e-26 91.9 0.7 3.1e-26 91.1 0.5 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain DUF1352 PF07086.7 EFI26523.1 - 0.14 11.7 3.2 0.22 11.1 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) BBE PF08031.7 EFI26524.1 - 1.2e-11 44.3 0.1 2.7e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EFI26524.1 - 8.3e-09 35.0 0.5 1.6e-08 34.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Dehydratase_MU PF02288.10 EFI26525.1 - 0.062 13.0 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Dehydratase medium subunit Retrotrans_gag PF03732.12 EFI26526.1 - 0.0046 16.9 0.2 0.0046 16.9 0.1 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 EFI26526.1 - 0.72 9.8 6.3 1.4 8.9 4.4 1.5 1 0 0 1 1 1 0 Zinc knuckle IncA PF04156.9 EFI26526.1 - 1.2 8.7 2.3 2.3 7.7 1.6 1.4 1 0 0 1 1 1 0 IncA protein GST_N_3 PF13417.1 EFI26528.1 - 1.3e-12 47.7 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EFI26528.1 - 6.2e-11 42.3 0.0 9.4e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EFI26528.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EFI26528.1 - 0.026 14.4 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EFI26528.1 - 0.1 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EFI26529.1 - 2.4e-13 50.0 0.0 4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EFI26529.1 - 1.5e-12 47.5 0.0 3.6e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EFI26529.1 - 6.9e-09 35.5 0.0 1.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Helitron_like_N PF14214.1 EFI26531.1 - 1e-59 201.4 0.0 1.2e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF3296 PF11726.3 EFI26531.1 - 4.5e-05 23.1 0.1 7.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3296) Phage_GPA PF05840.8 EFI26531.1 - 0.2 10.3 0.6 0.41 9.3 0.4 1.7 1 1 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Mgr1 PF08602.5 EFI26534.1 - 0.0032 16.5 0.0 0.0034 16.4 0.0 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Vac_Fusion PF02346.11 EFI26534.1 - 0.0042 16.4 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 Chordopoxvirus fusion protein COG5 PF10392.4 EFI26534.1 - 0.056 13.4 0.1 0.073 13.0 0.1 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3931 PF13082.1 EFI26536.1 - 0.049 13.4 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) Ion_trans PF00520.26 EFI26538.1 - 0.0077 15.4 1.2 0.47 9.6 0.0 2.2 1 1 1 2 2 2 2 Ion transport protein DUF1319 PF07028.6 EFI26539.1 - 0.15 12.2 1.7 0.27 11.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) F-box-like PF12937.2 EFI26541.1 - 3.5e-07 29.8 0.1 1.3e-06 28.0 0.1 2.0 1 1 0 1 1 1 1 F-box-like DUF1996 PF09362.5 EFI26543.1 - 7.8e-05 22.4 0.3 9e-05 22.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EFI26544.1 - 7.6e-70 235.2 0.0 1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EFI26545.1 - 0.004 16.8 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fasciclin PF02469.17 EFI26546.1 - 1.2e-28 99.7 0.0 5.9e-20 71.5 0.1 2.6 2 0 0 2 2 2 2 Fasciclin domain HEAT_2 PF13646.1 EFI26546.1 - 2.6e-09 37.2 20.0 0.00025 21.2 0.1 8.1 7 3 2 9 9 9 3 HEAT repeats HEAT PF02985.17 EFI26546.1 - 0.0021 18.0 14.9 0.75 10.0 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 EFI26546.1 - 0.13 12.1 5.0 70 3.4 0.1 5.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DctQ PF04290.7 EFI26547.1 - 0.013 15.2 1.7 0.06 13.0 1.1 2.0 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3859 PF12975.2 EFI26548.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3859) DUF1418 PF07214.7 EFI26549.1 - 0.19 11.3 1.6 0.57 9.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) DUF1772 PF08592.6 EFI26549.1 - 4 7.1 9.4 5.8 6.6 1.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF1772) Glycoprotein_B PF00606.13 EFI26550.1 - 1.1 7.1 0.1 1.8 6.4 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Med4 PF10018.4 EFI26551.1 - 0.041 13.2 0.4 0.078 12.3 0.3 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3439 PF11921.3 EFI26560.1 - 0.013 15.2 15.5 0.34 10.6 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Gamma-thionin PF00304.15 EFI26562.1 - 0.022 14.7 2.5 0.04 13.9 1.7 1.4 1 0 0 1 1 1 0 Gamma-thionin family Toxin_38 PF14866.1 EFI26562.1 - 0.078 13.0 1.2 0.15 12.1 0.8 1.4 1 0 0 1 1 1 0 Potassium channel toxin DUF605 PF04652.11 EFI26562.1 - 0.38 10.1 8.0 0.47 9.7 5.5 1.2 1 0 0 1 1 1 0 Vta1 like CAF-1_p150 PF11600.3 EFI26562.1 - 8 5.7 6.6 10 5.3 4.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FTSW_RODA_SPOVE PF01098.14 EFI26566.1 - 2.4 6.8 5.5 2.9 6.5 3.8 1.1 1 0 0 1 1 1 0 Cell cycle protein Robl_LC7 PF03259.12 EFI26568.1 - 1.7e-06 27.4 0.1 0.00039 19.9 0.0 2.5 2 1 0 2 2 2 2 Roadblock/LC7 domain DUF4243 PF14027.1 EFI26569.1 - 1.5e-81 274.4 0.0 2.1e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) FHA PF00498.21 EFI26570.1 - 2.3e-11 43.6 0.1 7.2e-11 42.0 0.1 1.9 1 0 0 1 1 1 1 FHA domain NACHT PF05729.7 EFI26570.1 - 1.7e-10 40.7 0.0 4.4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EFI26570.1 - 0.0065 16.4 3.5 0.0074 16.2 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EFI26570.1 - 0.012 15.7 0.0 0.12 12.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EFI26570.1 - 0.03 13.7 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Reo_sigmaC PF04582.7 EFI26570.1 - 0.037 13.2 5.1 0.08 12.1 3.5 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EFI26570.1 - 0.063 13.1 7.4 0.17 11.7 1.8 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 EFI26570.1 - 0.16 12.1 9.6 2.1 8.5 3.7 2.9 2 1 0 2 2 2 0 Syntaxin SPX PF03105.14 EFI26570.1 - 0.66 9.6 10.7 63 3.2 7.4 2.6 1 1 0 1 1 1 0 SPX domain TBPIP PF07106.8 EFI26570.1 - 0.75 9.3 7.2 1.4 8.4 1.2 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EFI26570.1 - 2.2 8.5 9.7 70 3.7 0.3 3.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.8 EFI26570.1 - 3.3 8.1 8.7 4.6 7.6 0.8 3.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.8 EFI26570.1 - 3.9 6.4 9.0 0.91 8.5 0.9 2.1 1 1 1 2 2 2 0 TMPIT-like protein Phage_GPO PF05929.6 EFI26570.1 - 6.2 5.9 8.6 12 5.0 3.8 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase SAC3_GANP PF03399.11 EFI26573.1 - 4e-24 85.3 0.1 7.3e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Phage_lambda_P PF06992.6 EFI26573.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Replication protein P API5 PF05918.6 EFI26573.1 - 1.7 7.0 6.1 2.8 6.3 4.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MFS_1 PF07690.11 EFI26574.1 - 1.2e-40 139.2 45.0 1.4e-38 132.5 33.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EFI26574.1 - 2.3e-05 22.7 16.4 0.0005 18.3 11.3 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rad60-SLD PF11976.3 EFI26577.1 - 1.2e-11 44.1 0.0 1.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EFI26577.1 - 0.00014 21.1 0.0 0.00019 20.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family PB1 PF00564.19 EFI26577.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 PB1 domain TUG-UBL1 PF11470.3 EFI26577.1 - 0.046 13.6 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Abhydrolase_3 PF07859.8 EFI26578.1 - 3.6e-18 65.9 0.0 6e-18 65.1 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EFI26578.1 - 3.9e-09 36.3 0.0 5.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EFI26578.1 - 2.4e-07 29.8 0.0 0.0007 18.4 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.2 EFI26578.1 - 1.9e-05 24.6 0.2 2.9e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EFI26578.1 - 0.006 15.4 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF1749 PF08538.5 EFI26578.1 - 0.0092 14.9 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF2424 PF10340.4 EFI26578.1 - 0.12 10.9 0.0 0.2 10.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) Zip PF02535.17 EFI26579.1 - 1.1e-42 146.2 33.0 7.1e-33 113.9 0.4 3.5 2 1 1 3 3 3 2 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EFI26579.1 - 0.0067 15.3 5.8 0.0067 15.3 4.0 2.2 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor DUF3357 PF11837.3 EFI26579.1 - 0.063 13.1 0.2 4.2 7.2 0.0 3.8 4 2 1 5 5 5 0 Domain of unknown function (DUF3357) CbtA PF09490.5 EFI26579.1 - 0.078 12.2 4.0 0.34 10.1 0.8 2.7 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) NACHT PF05729.7 EFI26580.1 - 0.00026 20.6 0.5 0.23 11.1 0.0 2.1 1 1 1 2 2 2 2 NACHT domain AAA_24 PF13479.1 EFI26580.1 - 0.0043 16.6 0.2 0.016 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EFI26580.1 - 0.0063 16.5 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EFI26580.1 - 0.0097 16.1 0.0 0.016 15.4 0.0 1.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EFI26580.1 - 0.071 12.4 0.2 4.3 6.6 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 EFI26580.1 - 0.09 12.9 0.0 0.14 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EFI26580.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein UPF0079 PF02367.12 EFI26580.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 zf-C2H2 PF00096.21 EFI26581.1 - 4.8e-10 39.1 12.5 4.6e-05 23.5 0.2 4.3 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EFI26581.1 - 2.2e-07 30.8 7.8 7.4e-07 29.1 0.1 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EFI26581.1 - 3.7e-06 26.8 16.3 0.001 19.2 0.2 4.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EFI26581.1 - 5.6e-05 22.8 0.3 0.17 11.8 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EFI26581.1 - 0.031 14.4 2.0 3.9 7.8 0.0 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EFI26581.1 - 0.04 14.0 3.1 4.7 7.4 0.4 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EFI26581.1 - 0.2 11.8 3.7 2.5 8.3 0.0 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Surp PF01805.15 EFI26583.1 - 0.0057 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Surp module AAA_22 PF13401.1 EFI26583.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EFI26583.1 - 0.28 11.1 4.3 3.7 7.4 3.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain DRY_EERY PF09750.4 EFI26583.1 - 0.89 9.6 0.0 0.89 9.6 0.0 2.9 2 1 0 2 2 2 0 Alternative splicing regulator HlyD PF00529.15 EFI26583.1 - 1.5 8.0 5.9 2.1 7.5 0.7 2.3 2 0 0 2 2 2 0 HlyD family secretion protein Lactamase_B PF00753.22 EFI26584.1 - 2.2e-07 30.7 0.2 4.9e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EFI26584.1 - 2.9e-05 23.6 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CAF-1_p150 PF11600.3 EFI26587.1 - 0.013 14.8 42.3 0.013 14.8 19.4 4.3 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FHA PF00498.21 EFI26588.1 - 0.0065 16.5 0.2 0.032 14.3 0.1 2.0 1 1 0 1 1 1 1 FHA domain ABC1 PF03109.11 EFI26591.1 - 2.2e-24 85.7 1.8 5.6e-24 84.3 1.2 1.7 1 1 0 1 1 1 1 ABC1 family APH PF01636.18 EFI26591.1 - 0.0061 16.3 0.0 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RepB-RCR_reg PF10723.4 EFI26591.1 - 0.056 13.1 1.8 0.12 12.0 1.3 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB Saccharop_dh PF03435.13 EFI26592.1 - 1.9e-67 227.9 0.0 7.2e-67 226.0 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 EFI26592.1 - 5.4e-12 45.8 0.0 3.8e-11 43.1 0.0 2.3 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EFI26592.1 - 6.5e-12 45.3 0.0 1.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EFI26592.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EFI26592.1 - 0.012 15.8 0.1 0.039 14.2 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EFI26592.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RAP1 PF07218.6 EFI26592.1 - 1.4 6.8 5.8 2.2 6.2 4.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-AN1 PF01428.11 EFI26595.1 - 4.1 7.3 14.2 2.4 8.0 6.5 2.1 1 1 1 2 2 2 0 AN1-like Zinc finger FtsX PF02687.16 EFI26597.1 - 0.0057 16.4 0.7 0.0057 16.4 0.5 2.7 3 0 0 3 3 3 1 FtsX-like permease family DUF4218 PF13960.1 EFI26599.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) FAM216B PF15107.1 EFI26600.1 - 0.089 12.6 0.0 2.7 7.8 0.0 2.3 1 1 1 2 2 2 0 FAM216B protein family Ferritin PF00210.19 EFI26600.1 - 0.13 12.0 0.0 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 Ferritin-like domain Rabaptin PF03528.10 EFI26601.1 - 0.045 13.6 0.2 0.05 13.5 0.1 1.1 1 0 0 1 1 1 0 Rabaptin Claudin_2 PF13903.1 EFI26603.1 - 0.035 13.8 0.9 0.043 13.4 0.7 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1673 PF07895.6 EFI26603.1 - 0.069 12.6 0.6 0.091 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) MHYT PF03707.11 EFI26603.1 - 0.08 13.0 0.6 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat AT_hook PF02178.14 EFI26605.1 - 0.00096 18.5 11.9 0.031 13.9 1.5 2.4 2 0 0 2 2 2 2 AT hook motif Fasciclin PF02469.17 EFI26608.1 - 2.4e-25 88.9 0.4 1e-14 54.6 0.1 3.2 3 0 0 3 3 3 2 Fasciclin domain Ubiq_cyt_C_chap PF03981.7 EFI26612.1 - 0.062 13.1 0.0 0.065 13.0 0.0 1.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone GMC_oxred_N PF00732.14 EFI26614.1 - 8.4e-53 179.4 0.0 1.3e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EFI26614.1 - 4.9e-34 117.6 0.1 7.9e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EFI26614.1 - 1.4e-06 27.4 1.1 0.00051 19.0 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EFI26614.1 - 2.8e-05 23.1 0.3 0.00018 20.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EFI26614.1 - 0.00011 22.1 0.4 0.00031 20.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EFI26614.1 - 0.0002 20.4 0.0 0.00036 19.5 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EFI26614.1 - 0.00036 20.6 0.1 0.028 14.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EFI26614.1 - 0.0024 17.7 0.0 0.0092 15.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EFI26614.1 - 0.028 13.4 0.2 0.053 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EFI26614.1 - 0.071 12.8 0.2 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EFI26614.1 - 0.087 11.6 0.2 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EFI26614.1 - 0.17 10.3 1.0 0.37 9.2 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF4391 PF14335.1 EFI26615.1 - 0.081 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF2334 PF10096.4 EFI26616.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) p450 PF00067.17 EFI26618.1 - 1.3e-65 221.7 0.0 1.7e-65 221.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_halogenase PF04820.9 EFI26619.1 - 1.3e-28 99.8 0.2 1.9e-14 53.1 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EFI26619.1 - 4.9e-14 52.1 0.0 1.5e-13 50.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EFI26619.1 - 2.9e-09 36.2 0.0 4.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EFI26619.1 - 6.1e-07 29.5 0.0 1.5e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EFI26619.1 - 1e-06 28.1 0.0 2.7e-06 26.7 0.0 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EFI26619.1 - 1.1e-06 28.5 0.2 4.1e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EFI26619.1 - 7.2e-05 21.8 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EFI26619.1 - 9.1e-05 22.7 0.1 0.001 19.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EFI26619.1 - 0.00022 19.8 0.0 0.00036 19.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EFI26619.1 - 0.00034 19.5 0.1 0.0007 18.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EFI26619.1 - 0.0076 15.3 0.0 0.076 12.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_10 PF13460.1 EFI26619.1 - 0.015 15.3 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EFI26619.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EFI26619.1 - 0.028 13.8 0.1 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PUD PF03714.9 EFI26619.1 - 0.06 13.4 0.3 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Bacterial pullanase-associated domain NAD_Gly3P_dh_N PF01210.18 EFI26619.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 EFI26619.1 - 0.078 12.5 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EFI26619.1 - 0.09 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EFI26619.1 - 0.097 11.5 0.0 0.24 10.2 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Sad1_UNC PF07738.8 EFI26622.1 - 6.8e-05 22.6 0.0 0.00019 21.2 0.0 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Patched PF02460.13 EFI26623.1 - 0.1 10.4 0.0 0.13 10.1 0.0 1.1 1 0 0 1 1 1 0 Patched family GldM_C PF12080.3 EFI26624.1 - 0.035 14.0 0.6 0.039 13.8 0.4 1.1 1 0 0 1 1 1 0 GldM C-terminal domain Seryl_tRNA_N PF02403.17 EFI26624.1 - 0.16 11.9 4.4 0.2 11.6 3.0 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UXS1_N PF11803.3 EFI26624.1 - 0.26 11.0 2.1 0.63 9.8 0.1 2.2 2 1 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal FlgN PF05130.7 EFI26624.1 - 0.26 11.5 5.0 0.32 11.2 3.5 1.1 1 0 0 1 1 1 0 FlgN protein FlxA PF14282.1 EFI26624.1 - 0.29 11.0 2.7 0.39 10.6 1.9 1.3 1 0 0 1 1 1 0 FlxA-like protein EssA PF10661.4 EFI26624.1 - 0.57 9.8 4.1 0.45 10.1 2.1 1.4 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF1451 PF07295.6 EFI26624.1 - 0.65 9.7 3.0 0.74 9.5 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF4404 PF14357.1 EFI26624.1 - 0.71 10.3 4.1 8 6.9 2.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) BatA PF07584.6 EFI26624.1 - 1.4 9.1 4.2 3.8 7.7 2.8 1.9 1 1 1 2 2 2 0 Aerotolerance regulator N-terminal XPG_I PF00867.13 EFI26625.1 - 3.9e-14 52.4 0.0 1.3e-13 50.8 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EFI26625.1 - 0.00014 22.0 0.0 0.00082 19.5 0.0 2.3 2 1 0 2 2 2 1 XPG N-terminal domain SET PF00856.23 EFI26627.1 - 2.4e-10 40.9 1.4 6.3e-09 36.3 0.0 3.2 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 EFI26627.1 - 1.1e-07 31.9 11.9 7.7e-07 29.3 5.9 3.0 2 1 0 2 2 2 1 Pre-SET motif DUF1908 PF08926.6 EFI26629.1 - 0.0012 17.6 0.1 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) DUF1136 PF06582.7 EFI26632.1 - 0.02 14.5 0.0 0.061 13.0 0.0 1.8 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) Alveol-reg_P311 PF11092.3 EFI26632.1 - 0.08 12.9 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Neuronal protein 3.1 (p311) Bac_transf PF02397.11 EFI26633.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial sugar transferase UQ_con PF00179.21 EFI26637.1 - 1e-35 122.2 0.0 2.9e-34 117.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.1 EFI26638.1 - 8e-14 51.1 6.2 1.2e-13 50.5 4.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EFI26638.1 - 3e-08 33.6 1.5 5.1e-08 32.9 1.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EFI26638.1 - 1.8e-07 30.7 3.8 2.7e-07 30.1 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EFI26638.1 - 5.3e-07 29.1 5.3 8.3e-07 28.5 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EFI26638.1 - 6.7e-07 29.2 5.2 1.1e-06 28.6 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EFI26638.1 - 8.2e-07 28.6 3.3 1.2e-06 28.0 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EFI26638.1 - 0.00028 20.6 1.4 0.0005 19.8 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EFI26638.1 - 0.00048 20.1 3.3 0.00078 19.4 2.3 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 EFI26638.1 - 0.0033 16.9 2.0 0.0065 15.9 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EFI26638.1 - 0.02 14.4 4.8 0.042 13.4 3.3 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EFI26638.1 - 0.1 12.3 8.1 0.032 13.9 0.5 2.4 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EFI26638.1 - 0.19 11.6 5.2 0.98 9.4 3.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Rtf2 PF04641.7 EFI26638.1 - 0.2 10.8 0.2 0.42 9.7 0.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger PHD PF00628.24 EFI26638.1 - 0.59 9.8 3.9 1 9.1 2.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-P11 PF03854.9 EFI26638.1 - 2.2 7.8 4.7 0.99 8.9 0.8 1.9 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_1 PF14446.1 EFI26638.1 - 3.4 7.4 5.1 35 4.2 3.6 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 GMC_oxred_N PF00732.14 EFI26641.1 - 4.7e-66 222.9 0.0 5.9e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EFI26641.1 - 3.7e-08 33.7 0.0 9e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EFI26641.1 - 1.6e-06 28.0 0.0 0.00024 21.0 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EFI26641.1 - 4.3e-05 22.5 0.0 6.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EFI26641.1 - 4.7e-05 22.4 0.0 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EFI26641.1 - 6.3e-05 22.0 0.0 0.026 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EFI26641.1 - 0.0012 18.8 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EFI26641.1 - 0.015 13.9 0.3 0.04 12.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EFI26641.1 - 0.048 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EFI26641.1 - 0.085 12.9 0.0 3.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EFI26642.1 - 7.9e-61 205.7 0.0 1.4e-60 205.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EFI26642.1 - 5.7e-31 107.7 0.1 1.2e-30 106.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EFI26642.1 - 0.0051 16.8 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Cyt-b5 PF00173.23 EFI26645.1 - 3e-15 55.7 0.0 5.4e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EFI26645.1 - 0.0014 18.1 6.4 0.0021 17.5 4.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase tRNA-synt_2b PF00587.20 EFI26646.1 - 4.9e-51 172.7 0.0 8.7e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EFI26646.1 - 3.1e-19 68.6 0.0 8.5e-19 67.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Muted PF14942.1 EFI26650.1 - 0.14 12.0 2.4 0.43 10.4 1.7 1.8 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Oxidored_q2 PF00420.19 EFI26651.1 - 0.049 13.2 0.3 0.049 13.2 0.2 1.0 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L EphA2_TM PF14575.1 EFI26651.1 - 0.61 10.5 3.4 0.6 10.5 2.4 1.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain P12 PF12669.2 EFI26651.1 - 1.4 9.1 5.6 1.4 9.1 3.9 1.1 1 0 0 1 1 1 0 Virus attachment protein p12 family MacB_PCD PF12704.2 EFI26651.1 - 2.4 7.6 4.6 2.5 7.6 3.2 1.0 1 0 0 1 1 1 0 MacB-like periplasmic core domain Protocadherin PF08374.6 EFI26651.1 - 4.2 6.9 5.2 3.8 7.0 3.6 1.0 1 0 0 1 1 1 0 Protocadherin DUF2970 PF11174.3 EFI26651.1 - 5 6.7 9.8 5 6.7 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF515 PF04415.7 EFI26651.1 - 5.5 5.1 5.8 4.8 5.2 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Synaptobrevin PF00957.16 EFI26651.1 - 7.9 6.1 9.7 8.5 6.0 6.7 1.0 1 0 0 1 1 1 0 Synaptobrevin Synaptobrevin PF00957.16 EFI26652.1 - 5.5e-22 77.1 0.3 7.8e-22 76.6 0.2 1.2 1 0 0 1 1 1 1 Synaptobrevin Pkinase PF00069.20 EFI26653.1 - 4.7e-59 199.6 0.0 7e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI26653.1 - 1.1e-28 100.0 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI26653.1 - 4.3e-11 42.3 0.0 6.4e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EFI26653.1 - 0.017 14.1 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GAS PF13851.1 EFI26654.1 - 0.12 11.5 2.2 0.49 9.5 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HR1 PF02185.11 EFI26654.1 - 0.25 11.0 0.2 0.25 11.0 0.1 2.1 2 0 0 2 2 2 0 Hr1 repeat CCDC-167 PF15188.1 EFI26654.1 - 0.4 10.6 3.8 0.25 11.2 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TMF_DNA_bd PF12329.3 EFI26654.1 - 0.43 10.4 6.5 0.073 12.8 1.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.15 EFI26654.1 - 0.49 10.1 5.9 4.4 7.1 1.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EFI26654.1 - 2.2 7.8 5.2 1.4 8.5 0.3 2.6 2 1 0 3 3 3 0 Septum formation initiator Pox_A_type_inc PF04508.7 EFI26654.1 - 2.4 8.1 8.9 0.66 9.9 0.4 3.2 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat DUF4140 PF13600.1 EFI26654.1 - 4 7.9 7.2 13 6.3 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Amino_oxidase PF01593.19 EFI26657.1 - 1.3e-35 123.3 0.1 3.8e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EFI26657.1 - 1.9e-12 46.9 0.7 5.5e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EFI26657.1 - 0.0004 19.5 1.3 0.00059 18.9 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EFI26657.1 - 0.0051 15.7 0.3 0.0082 15.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EFI26657.1 - 0.04 13.8 0.4 0.081 12.7 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EFI26657.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EFI26657.1 - 0.089 11.2 0.3 0.13 10.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EFI26657.1 - 0.19 10.7 0.2 0.58 9.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 EFI26657.1 - 0.31 10.0 0.6 0.55 9.2 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EFI26657.1 - 0.32 9.7 0.1 0.48 9.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Ank PF00023.25 EFI26658.1 - 4.3e-64 209.3 6.1 3.8e-06 26.4 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_2 PF12796.2 EFI26658.1 - 6.2e-57 189.9 7.0 6.6e-14 52.0 0.1 6.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EFI26658.1 - 1.4e-48 162.3 6.3 4.5e-08 33.3 0.0 7.4 5 2 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EFI26658.1 - 3.8e-43 141.1 0.4 0.00016 21.5 0.0 11.9 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 EFI26658.1 - 2.2e-38 129.3 12.4 1.3e-06 28.3 0.1 10.1 1 1 9 10 10 10 10 Ankyrin repeats (many copies) NapD PF03927.8 EFI26658.1 - 0.055 13.3 0.3 13 5.6 0.0 4.4 2 1 2 4 4 4 0 NapD protein Pyridox_oxidase PF01243.15 EFI26661.1 - 5.4e-05 23.1 0.0 0.061 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 EFI26662.1 - 2.7e-26 92.2 0.0 1.9e-25 89.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI26662.1 - 1.5e-08 34.0 0.0 1e-05 24.7 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RRM_5 PF13893.1 EFI26663.1 - 2.6e-10 39.9 0.0 5.8e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EFI26663.1 - 6.2e-10 38.5 0.0 1.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI26663.1 - 1.9e-09 37.3 0.0 3.4e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mito_fiss_reg PF05308.6 EFI26663.1 - 9.6 5.4 8.6 1 8.6 2.7 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Spc97_Spc98 PF04130.8 EFI26669.1 - 1.1e-123 413.3 0.1 1.4e-123 413.0 0.1 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family CUE PF02845.11 EFI26670.1 - 1.1e-10 40.7 0.0 1.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain SUZ PF12752.2 EFI26670.1 - 0.036 14.5 0.0 4.7 7.8 0.0 2.5 1 1 1 2 2 2 0 SUZ domain Peptidase_S46 PF10459.4 EFI26674.1 - 0.78 8.0 3.0 1 7.6 2.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Nucleoplasmin PF03066.10 EFI26675.1 - 0.053 13.0 3.0 0.087 12.3 2.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EFI26675.1 - 3.8 7.7 9.2 0.93 9.6 1.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pox_RNA_Pol_19 PF05320.7 EFI26675.1 - 9.6 5.9 9.3 1.1 9.0 2.2 2.4 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit zf-RING_5 PF14634.1 EFI26676.1 - 4.7e-08 32.6 8.5 4.7e-08 32.6 5.9 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EFI26676.1 - 2.3e-07 30.5 9.9 4.8e-07 29.5 6.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EFI26676.1 - 5.3e-05 22.8 3.3 5.3e-05 22.8 2.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EFI26676.1 - 0.00011 22.1 11.5 0.00021 21.2 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EFI26676.1 - 0.00021 20.8 9.9 0.00049 19.6 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EFI26676.1 - 0.00061 19.6 8.8 0.0099 15.7 6.5 2.4 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EFI26676.1 - 0.0057 16.2 8.7 0.011 15.3 6.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 EFI26676.1 - 0.01 15.0 0.6 0.01 15.0 0.4 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger IBR PF01485.16 EFI26676.1 - 0.021 14.7 5.7 0.064 13.1 3.9 1.8 1 1 0 1 1 1 0 IBR domain HALZ PF02183.13 EFI26676.1 - 0.047 13.4 2.9 0.1 12.3 2.0 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DDRGK PF09756.4 EFI26676.1 - 0.064 12.6 3.8 0.096 12.0 2.6 1.1 1 0 0 1 1 1 0 DDRGK domain FYVE PF01363.16 EFI26676.1 - 0.3 11.0 8.9 1.5 8.7 6.1 2.5 1 1 0 1 1 1 0 FYVE zinc finger DUF1311 PF07007.7 EFI26676.1 - 0.32 11.1 6.7 0.67 10.0 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) IncA PF04156.9 EFI26676.1 - 0.41 10.2 6.5 0.55 9.7 4.5 1.1 1 0 0 1 1 1 0 IncA protein DUF3039 PF11238.3 EFI26676.1 - 0.43 10.0 5.0 1.2 8.6 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Bestrophin PF01062.16 EFI26676.1 - 0.58 9.0 2.0 0.86 8.4 1.4 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel zf-rbx1 PF12678.2 EFI26676.1 - 0.69 10.0 6.6 0.46 10.6 3.0 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_6 PF14835.1 EFI26676.1 - 0.73 9.6 7.9 2.2 8.1 5.5 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DUF1272 PF06906.6 EFI26676.1 - 0.73 9.7 7.7 2.1 8.2 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF349 PF03993.7 EFI26676.1 - 1.7 8.8 9.3 3.5 7.8 6.1 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) Mnd1 PF03962.10 EFI26676.1 - 3.3 7.3 10.0 2.9 7.4 6.3 1.3 1 1 0 1 1 1 0 Mnd1 family Pheromone PF08015.6 EFI26679.1 - 0.022 15.6 2.9 0.032 15.0 0.2 1.9 1 1 1 2 2 2 0 Fungal mating-type pheromone Abhydrolase_6 PF12697.2 EFI26682.1 - 4.2e-17 62.7 0.8 8.4e-17 61.8 0.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EFI26682.1 - 9.8e-17 61.0 0.0 1.9e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EFI26682.1 - 3.8e-08 33.1 0.0 5.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EFI26682.1 - 6.8e-08 32.3 0.0 3.2e-07 30.1 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EFI26682.1 - 0.00021 20.9 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.3 EFI26682.1 - 0.0012 18.6 0.1 0.0026 17.5 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EFI26682.1 - 0.0015 17.8 0.2 0.0043 16.2 0.1 1.8 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF3089 PF11288.3 EFI26682.1 - 0.012 14.7 0.0 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.11 EFI26682.1 - 0.013 14.9 0.1 0.6 9.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF818 PF05677.7 EFI26682.1 - 0.015 14.0 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Lipase PF00151.14 EFI26682.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipase Thioesterase PF00975.15 EFI26682.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 EFI26682.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.8 EFI26682.1 - 0.079 12.5 0.2 0.6 9.6 0.1 2.0 1 1 0 1 1 1 0 PGAP1-like protein COesterase PF00135.23 EFI26682.1 - 0.094 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family ABC_membrane PF00664.18 EFI26686.1 - 7.2e-16 58.4 7.0 1.3e-15 57.5 4.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EFI26687.1 - 5.1e-42 143.4 0.0 1.9e-29 102.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EFI26687.1 - 1.2e-29 103.5 15.1 1.8e-29 103.0 10.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EFI26687.1 - 1.1e-07 31.3 0.8 0.0011 18.2 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EFI26687.1 - 2.8e-05 24.2 0.0 1.8 8.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EFI26687.1 - 0.0011 18.9 0.7 0.0044 17.0 0.2 2.2 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EFI26687.1 - 0.0042 17.0 0.1 0.013 15.4 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EFI26687.1 - 0.0055 17.2 0.1 0.014 15.8 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein SbcCD_C PF13558.1 EFI26687.1 - 0.006 16.4 1.7 0.61 10.0 0.1 3.7 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EFI26687.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EFI26687.1 - 0.036 14.2 0.1 0.33 11.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EFI26687.1 - 0.054 12.4 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ArgK PF03308.11 EFI26687.1 - 0.056 12.2 0.2 0.092 11.5 0.1 1.2 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 EFI26687.1 - 0.11 11.6 0.1 0.23 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EFI26687.1 - 0.13 12.1 0.2 0.32 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EFI26687.1 - 0.13 11.3 0.1 0.34 9.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin zf-C2H2 PF00096.21 EFI26689.1 - 7 7.2 6.6 1.8 9.0 1.9 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type SAE2 PF08573.5 EFI26691.1 - 2.4e-17 63.4 1.6 2.4e-17 63.4 1.1 2.7 3 1 0 3 3 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus bZIP_1 PF00170.16 EFI26691.1 - 0.00038 20.3 6.0 0.034 14.0 0.6 2.7 2 0 0 2 2 2 2 bZIP transcription factor Rootletin PF15035.1 EFI26691.1 - 0.0012 18.8 12.1 0.0019 18.2 5.1 2.5 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion GAS PF13851.1 EFI26691.1 - 0.0019 17.4 3.4 0.0019 17.4 2.4 2.4 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EFI26691.1 - 0.026 14.8 6.4 0.047 14.0 1.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EFI26691.1 - 0.2 11.9 4.6 1.7 8.9 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ING PF12998.2 EFI26691.1 - 0.26 11.5 6.8 1 9.6 1.4 2.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Spectrin PF00435.16 EFI26691.1 - 0.43 10.8 5.4 0.76 10.0 0.4 3.1 3 0 0 3 3 3 0 Spectrin repeat IncA PF04156.9 EFI26691.1 - 0.48 10.0 18.4 0.018 14.6 4.8 3.2 3 1 0 4 4 4 0 IncA protein BRCA-2_OB3 PF09104.5 EFI26691.1 - 0.58 9.9 1.6 31 4.3 0.1 2.4 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 Nup54 PF13874.1 EFI26691.1 - 0.67 9.6 10.8 0.46 10.1 0.1 3.3 4 0 0 4 4 3 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.6 EFI26691.1 - 0.84 9.5 3.2 12 5.8 0.1 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TBPIP PF07106.8 EFI26691.1 - 0.94 9.0 6.4 2.4 7.6 0.4 2.6 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 EFI26691.1 - 2.6 5.7 7.1 3.8 5.2 4.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 EFI26691.1 - 3.9 7.3 10.8 10 6.0 1.8 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EFI26691.1 - 4 6.9 8.8 9.7 5.7 0.6 3.3 3 1 1 4 4 4 0 Septum formation initiator CCDC155 PF14662.1 EFI26691.1 - 9.4 5.7 13.4 13 5.3 2.4 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 Gp37_Gp68 PF07505.6 EFI26693.1 - 0.01 15.0 0.1 0.019 14.1 0.1 1.3 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Ndc1_Nup PF09531.5 EFI26696.1 - 5.3e-50 170.4 0.0 7.1e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup SKN1 PF03935.10 EFI26697.1 - 9.1e-181 601.3 3.8 1.9e-179 597.0 2.7 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) MIP-T3 PF10243.4 EFI26700.1 - 0.00073 18.1 40.1 0.00073 18.1 27.8 2.4 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 SKN1 PF03935.10 EFI26700.1 - 0.0012 17.0 0.0 0.0012 17.0 0.0 2.4 2 1 1 3 3 3 1 Beta-glucan synthesis-associated protein (SKN1) RR_TM4-6 PF06459.7 EFI26700.1 - 5.5 6.8 31.1 0.89 9.3 16.8 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.6 EFI26700.1 - 9.5 4.3 27.5 17 3.5 19.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.20 EFI26704.1 - 4.5e-35 121.0 0.0 6.2e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI26704.1 - 1.4e-08 34.1 0.0 3.7e-07 29.4 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EFI26704.1 - 0.027 13.2 0.1 0.039 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2312 PF10073.4 EFI26704.1 - 0.13 11.6 0.1 0.32 10.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) F-box PF00646.28 EFI26705.1 - 0.0036 16.9 0.4 0.0093 15.5 0.3 1.8 1 0 0 1 1 1 1 F-box domain IncA PF04156.9 EFI26709.1 - 0.0005 19.7 1.8 0.00058 19.5 1.3 1.1 1 0 0 1 1 1 1 IncA protein Nup54 PF13874.1 EFI26709.1 - 0.001 18.7 0.9 0.0015 18.2 0.6 1.2 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Docking PF08990.6 EFI26709.1 - 0.0011 18.1 0.4 0.011 14.9 0.0 2.5 2 0 0 2 2 2 1 Erythronolide synthase docking DUF4254 PF14063.1 EFI26709.1 - 0.0034 16.9 0.2 0.0043 16.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) TPR_MLP1_2 PF07926.7 EFI26709.1 - 0.0077 15.9 2.8 0.01 15.5 1.9 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 EFI26709.1 - 0.01 15.4 0.9 0.013 15.0 0.6 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V-SNARE PF05008.10 EFI26709.1 - 0.012 15.7 1.9 0.017 15.2 1.3 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus TroA PF01297.12 EFI26709.1 - 0.013 14.8 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Periplasmic solute binding protein family Spc7 PF08317.6 EFI26709.1 - 0.013 14.1 2.3 0.017 13.8 1.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 EFI26709.1 - 0.014 14.8 1.3 0.019 14.4 0.9 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Laminin_II PF06009.7 EFI26709.1 - 0.014 15.1 0.9 0.019 14.7 0.6 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF4200 PF13863.1 EFI26709.1 - 0.015 15.2 7.8 0.021 14.7 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Med4 PF10018.4 EFI26709.1 - 0.017 14.5 0.5 0.022 14.1 0.3 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HemX PF04375.9 EFI26709.1 - 0.021 13.4 0.5 0.025 13.1 0.4 1.1 1 0 0 1 1 1 0 HemX IFT57 PF10498.4 EFI26709.1 - 0.027 13.2 3.4 0.036 12.8 2.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 RasGAP_C PF03836.10 EFI26709.1 - 0.027 14.1 0.3 0.033 13.8 0.2 1.1 1 0 0 1 1 1 0 RasGAP C-terminus COG2 PF06148.6 EFI26709.1 - 0.031 14.1 2.0 0.051 13.4 1.4 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CotH PF08757.6 EFI26709.1 - 0.032 13.4 0.2 0.041 13.1 0.2 1.1 1 0 0 1 1 1 0 CotH protein Vps5 PF09325.5 EFI26709.1 - 0.036 13.3 3.1 0.048 12.9 2.2 1.1 1 0 0 1 1 1 0 Vps5 C terminal like DUF3584 PF12128.3 EFI26709.1 - 0.036 11.3 1.0 0.043 11.1 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BicD PF09730.4 EFI26709.1 - 0.038 12.3 3.7 0.047 12.0 2.6 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Cluap1 PF10234.4 EFI26709.1 - 0.041 13.0 0.5 0.05 12.8 0.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 zf-C4H2 PF10146.4 EFI26709.1 - 0.043 13.8 0.3 0.054 13.5 0.2 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein AAA_13 PF13166.1 EFI26709.1 - 0.044 12.2 0.4 0.054 11.9 0.3 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EFI26709.1 - 0.049 12.5 5.4 0.065 12.1 3.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2937 PF11157.3 EFI26709.1 - 0.066 12.5 0.5 0.079 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) IMD PF08397.6 EFI26709.1 - 0.082 12.2 0.5 0.11 11.7 0.4 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain ATG16 PF08614.6 EFI26709.1 - 0.085 12.6 4.8 0.12 12.2 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2130 PF09903.4 EFI26709.1 - 0.093 11.4 0.5 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Mnd1 PF03962.10 EFI26709.1 - 0.095 12.3 1.5 0.13 11.9 1.0 1.1 1 0 0 1 1 1 0 Mnd1 family FemAB PF02388.11 EFI26709.1 - 0.1 11.2 0.5 0.12 10.9 0.3 1.1 1 0 0 1 1 1 0 FemAB family APG6 PF04111.7 EFI26709.1 - 0.12 11.4 1.0 0.13 11.2 0.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Paramyxo_P PF01806.12 EFI26709.1 - 0.12 11.5 1.4 0.17 11.1 1.0 1.2 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region FlaC_arch PF05377.6 EFI26709.1 - 0.13 12.2 0.9 0.19 11.6 0.4 1.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) H-kinase_dim PF02895.9 EFI26709.1 - 0.14 12.4 2.9 0.25 11.7 2.0 1.4 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain EzrA PF06160.7 EFI26709.1 - 0.15 10.2 4.3 0.2 9.8 3.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GrpE PF01025.14 EFI26709.1 - 0.15 11.6 4.6 0.2 11.1 3.2 1.1 1 0 0 1 1 1 0 GrpE DDE_Tnp_IS66 PF03050.9 EFI26709.1 - 0.22 10.6 2.1 0.34 10.1 1.5 1.3 1 1 0 1 1 1 0 Transposase IS66 family Sugarporin_N PF11471.3 EFI26709.1 - 0.24 11.1 7.4 3.7 7.2 1.3 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension ADIP PF11559.3 EFI26709.1 - 0.24 11.2 6.8 0.34 10.8 4.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Vps51 PF08700.6 EFI26709.1 - 0.25 11.2 2.9 0.65 9.8 2.0 1.8 1 1 0 1 1 1 0 Vps51/Vps67 Sec8_exocyst PF04048.9 EFI26709.1 - 0.32 10.6 2.7 0.87 9.2 1.5 1.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF1043 PF06295.7 EFI26709.1 - 2.6 7.7 5.4 20 4.8 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) CobN-Mg_chel PF02514.11 EFI26710.1 - 0.0088 13.4 0.5 0.0083 13.5 0.3 1.0 1 0 0 1 1 1 1 CobN/Magnesium Chelatase Cytochrom_B562 PF07361.6 EFI26710.1 - 0.051 13.9 0.3 0.085 13.2 0.2 1.6 1 1 0 1 1 1 0 Cytochrome b562 DUF2419 PF10343.4 EFI26710.1 - 0.059 12.6 0.0 0.063 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2419) NPH3 PF03000.9 EFI26710.1 - 0.067 12.7 0.1 0.072 12.6 0.1 1.1 1 0 0 1 1 1 0 NPH3 family V-SNARE PF05008.10 EFI26710.1 - 0.069 13.3 0.2 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus HeLo PF14479.1 EFI26710.1 - 0.24 11.0 2.5 3.3 7.3 1.7 2.0 1 1 0 1 1 1 0 Prion-inhibition and propagation HisKA_3 PF07730.8 EFI26710.1 - 0.42 10.9 2.0 2.3 8.6 1.4 2.1 1 1 0 1 1 1 0 Histidine kinase RIH_assoc PF08454.6 EFI26716.1 - 0.051 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 RyR and IP3R Homology associated DNase_NucA_NucB PF14040.1 EFI26717.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB zf-CCHC_5 PF14787.1 EFI26718.1 - 0.32 10.5 5.1 0.82 9.2 3.5 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CFEM PF05730.6 EFI26722.1 - 2.2e-05 24.2 3.5 2.2e-05 24.2 2.5 2.6 2 1 0 2 2 2 1 CFEM domain DUF1996 PF09362.5 EFI26723.1 - 1.6e-44 152.3 0.0 2.7e-31 109.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) ABC_tran PF00005.22 EFI26724.1 - 5.4e-44 149.8 0.9 5e-25 88.3 0.0 4.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EFI26724.1 - 2.2e-12 47.5 0.0 0.0065 16.4 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EFI26724.1 - 7.3e-10 38.4 0.2 7.6e-07 28.5 0.0 3.7 3 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EFI26724.1 - 1.5e-08 34.8 0.7 0.0017 18.3 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EFI26724.1 - 1.3e-07 30.9 0.1 0.0041 16.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_tran_2 PF12848.2 EFI26724.1 - 1.5e-07 31.1 4.2 1.5e-07 31.1 2.9 3.2 3 0 0 3 3 2 1 ABC transporter AAA_29 PF13555.1 EFI26724.1 - 4.1e-07 29.4 0.0 0.002 17.6 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 EFI26724.1 - 3.5e-05 23.9 0.0 0.1 12.8 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EFI26724.1 - 6.2e-05 22.7 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 EFI26724.1 - 6.5e-05 23.3 0.2 0.078 13.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EFI26724.1 - 8.5e-05 22.4 0.1 0.082 12.8 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EFI26724.1 - 0.00019 22.2 0.5 0.19 12.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EFI26724.1 - 0.00021 21.0 0.1 0.45 10.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EFI26724.1 - 0.00024 20.6 2.6 0.43 10.0 0.0 3.7 4 0 0 4 4 4 2 FtsK/SpoIIIE family AAA PF00004.24 EFI26724.1 - 0.00045 20.4 0.0 0.87 9.7 0.0 3.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EFI26724.1 - 0.00046 20.0 0.0 1.3 8.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EFI26724.1 - 0.00047 19.6 0.0 0.3 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EFI26724.1 - 0.00059 19.4 0.1 0.11 12.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EFI26724.1 - 0.0017 17.8 0.1 0.22 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 EFI26724.1 - 0.0025 17.9 0.1 1.3 9.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EFI26724.1 - 0.0039 17.1 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EFI26724.1 - 0.0075 15.4 0.5 0.71 9.0 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_15 PF13175.1 EFI26724.1 - 0.0096 15.0 0.2 7.4 5.5 0.0 3.5 4 0 0 4 4 3 0 AAA ATPase domain DAP3 PF10236.4 EFI26724.1 - 0.0097 14.8 3.7 0.81 8.5 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.13 EFI26724.1 - 0.014 14.6 1.1 0.26 10.5 0.0 2.8 3 1 0 3 3 2 0 Ferrous iron transport protein B Miro PF08477.8 EFI26724.1 - 0.024 15.1 0.0 3.3 8.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 EFI26724.1 - 0.025 14.3 0.0 0.98 9.0 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EFI26724.1 - 0.048 13.9 4.4 4.8 7.5 0.0 3.5 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.10 EFI26724.1 - 0.071 11.7 0.0 0.21 10.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Tom22 PF04281.8 EFI26724.1 - 0.078 12.5 0.0 0.078 12.5 0.0 2.9 4 0 0 4 4 2 0 Mitochondrial import receptor subunit Tom22 PAP1 PF08601.5 EFI26724.1 - 0.13 11.9 8.4 0.016 14.8 1.8 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 FAD_binding_4 PF01565.18 EFI26725.1 - 3e-11 42.9 0.2 5e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Haemolytic PF01809.13 EFI26730.1 - 0.27 10.8 2.0 8.2 6.1 1.1 2.7 2 1 0 2 2 2 0 Haemolytic domain eIF3g PF12353.3 EFI26731.1 - 9.7e-42 141.9 2.8 1.3e-41 141.4 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EFI26731.1 - 2.2e-17 62.4 0.1 4e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI26731.1 - 3.3e-15 55.8 0.0 6.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI26731.1 - 9.9e-09 34.9 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pox_A14 PF05767.7 EFI26734.1 - 0.038 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Pox_I5 PF04713.7 EFI26736.1 - 0.092 12.4 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Poxvirus protein I5 HUN PF08729.5 EFI26747.1 - 1.5e-05 24.7 1.7 3.5e-05 23.5 1.2 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Vps5 PF09325.5 EFI26752.1 - 1.3e-05 24.5 1.5 0.027 13.7 0.1 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Glycoprotein_B PF00606.13 EFI26752.1 - 0.013 13.5 0.1 2.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B SseB_C PF14581.1 EFI26752.1 - 0.017 14.9 0.1 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 SseB protein C-terminal domain Glyco_hydro_67N PF03648.9 EFI26752.1 - 0.025 14.6 0.5 0.79 9.7 0.0 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 N-terminus Rad60-SLD_2 PF13881.1 EFI26752.1 - 0.049 13.5 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like SelB-wing_1 PF09105.5 EFI26752.1 - 0.087 12.5 3.4 6.2 6.5 0.0 2.8 3 0 0 3 3 3 0 Elongation factor SelB, winged helix TFIIA_gamma_N PF02268.11 EFI26757.1 - 3.7e-26 90.4 0.1 5.2e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EFI26757.1 - 2.6e-24 84.7 0.6 3.6e-24 84.3 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Mito_fiss_reg PF05308.6 EFI26758.1 - 0.14 11.4 2.3 0.19 11.0 1.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EFI26758.1 - 0.45 9.7 2.5 0.48 9.6 1.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Polysacc_deac_1 PF01522.16 EFI26760.1 - 3e-31 107.6 0.0 5e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Pkinase PF00069.20 EFI26761.1 - 2.1e-41 141.8 0.0 9.1e-28 97.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI26761.1 - 2.4e-22 79.2 0.0 3.7e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EFI26761.1 - 0.025 14.3 0.3 0.072 12.8 0.2 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family NPP PF08384.5 EFI26763.1 - 0.15 11.7 0.9 0.41 10.3 0.1 1.9 1 1 1 2 2 2 0 Pro-opiomelanocortin, N-terminal region HhH-GPD PF00730.20 EFI26765.1 - 1.4e-12 47.7 0.0 6.5e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EFI26765.1 - 6.1e-08 32.0 0.3 4.3e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 NUDIX domain HHH PF00633.18 EFI26765.1 - 0.0047 16.5 0.0 0.016 14.9 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif Glyco_hydro_4C PF11975.3 EFI26765.1 - 0.055 13.2 0.2 0.6 9.8 0.2 2.4 2 1 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain DUF3395 PF11875.3 EFI26766.1 - 5.8e-30 103.9 0.0 1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EFI26766.1 - 4e-18 64.9 0.2 9e-18 63.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Cyt-b5 PF00173.23 EFI26769.1 - 6.1e-21 74.0 0.2 1.4e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EFI26769.1 - 1.6e-09 38.1 17.3 1.6e-09 38.1 12.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AMP-binding PF00501.23 EFI26771.1 - 1.6e-70 237.6 0.0 2.2e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EFI26771.1 - 3.9e-62 209.4 0.0 7.6e-62 208.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EFI26771.1 - 1.4e-13 50.8 0.0 3.5e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EFI26771.1 - 2.2e-07 31.7 0.0 8.3e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EFI26771.1 - 2.4e-07 30.4 0.0 5.5e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.15 EFI26771.1 - 0.0029 16.5 0.3 0.0099 14.7 0.0 2.0 2 1 0 2 2 2 1 Condensation domain 3Beta_HSD PF01073.14 EFI26771.1 - 0.027 13.1 0.0 1.2 7.7 0.0 2.7 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NARP1 PF12569.3 EFI26772.1 - 1.2e-165 552.2 5.2 1.2e-165 552.2 3.6 2.4 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 EFI26772.1 - 1.3e-18 65.3 4.3 0.0056 16.5 0.0 10.0 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 EFI26772.1 - 1e-17 63.5 12.5 0.00017 21.1 0.0 7.3 6 2 1 7 7 7 5 TPR repeat TPR_14 PF13428.1 EFI26772.1 - 2.5e-14 52.4 9.4 0.0062 17.0 0.0 9.2 8 4 4 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EFI26772.1 - 1.5e-13 51.0 21.1 0.00065 20.2 0.4 7.8 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 EFI26772.1 - 8.8e-12 44.7 7.5 0.0018 18.2 0.1 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EFI26772.1 - 1.2e-10 41.5 11.6 0.0018 18.5 0.0 6.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EFI26772.1 - 1.1e-08 34.3 7.9 0.0025 17.3 0.1 7.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EFI26772.1 - 3.9e-07 29.3 5.0 0.22 11.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EFI26772.1 - 4.6e-06 26.6 6.8 0.013 15.5 0.6 4.4 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EFI26772.1 - 5.9e-06 26.0 0.6 0.58 10.4 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EFI26772.1 - 8.9e-06 25.8 6.0 1.1 9.8 0.1 7.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EFI26772.1 - 2.1e-05 24.5 5.3 2.3 8.8 0.0 5.0 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EFI26772.1 - 0.00051 19.6 3.4 0.23 11.3 0.0 5.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EFI26772.1 - 0.0024 17.6 6.6 6.7 6.6 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EFI26772.1 - 0.018 14.9 5.7 16 5.5 0.1 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EFI26772.1 - 0.12 12.2 0.0 0.12 12.2 0.0 4.5 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 EFI26772.1 - 0.21 11.8 10.9 0.16 12.2 1.3 4.1 3 1 0 4 4 4 0 Bacterial transcriptional activator domain R3H PF01424.17 EFI26774.1 - 4.5e-08 32.6 0.1 7.9e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EFI26774.1 - 0.00016 21.5 57.3 0.001 18.9 6.8 14.1 14 1 0 14 14 14 8 NF-X1 type zinc finger SIN1 PF05422.7 EFI26775.1 - 5.5e-29 101.0 0.0 2.3e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RA PF00788.18 EFI26775.1 - 0.00026 21.4 0.0 0.0043 17.4 0.0 2.3 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain RBD PF02196.10 EFI26775.1 - 0.018 14.7 0.1 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 Raf-like Ras-binding domain TUG-UBL1 PF11470.3 EFI26775.1 - 0.072 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG SIN1 PF05422.7 EFI26776.1 - 1.7e-07 30.1 0.2 2.1e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) p450 PF00067.17 EFI26777.1 - 1.3e-62 211.8 0.0 2e-43 148.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 TEBP_beta PF07404.6 EFI26779.1 - 0.065 12.3 1.1 0.068 12.2 0.7 1.0 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) p450 PF00067.17 EFI26780.1 - 2e-58 198.0 0.0 6.8e-55 186.4 0.0 2.6 1 1 1 2 2 2 2 Cytochrome P450 GxGYxYP PF14323.1 EFI26780.1 - 0.11 11.1 0.0 0.23 10.1 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function FA_desaturase PF00487.19 EFI26781.1 - 6.9e-16 58.4 22.7 1.3e-15 57.5 15.7 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EFI26781.1 - 9.2e-14 51.0 0.0 2.2e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nbl1_Borealin_N PF10444.4 EFI26782.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal DUF1768 PF08719.6 EFI26783.1 - 9.1e-39 132.7 0.0 2.3e-38 131.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) La PF05383.12 EFI26783.1 - 4.9e-16 58.2 0.0 8.2e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 La domain DUF399 PF04187.8 EFI26784.1 - 0.073 12.5 0.4 0.086 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF399 S1-P1_nuclease PF02265.11 EFI26787.1 - 2.3e-15 56.9 0.0 1.4e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 S1/P1 Nuclease Pmp3 PF01679.12 EFI26790.1 - 9.5e-20 70.0 7.5 1.2e-19 69.7 5.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4173 PF13777.1 EFI26791.1 - 6.2 6.0 7.7 38 3.4 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) PIGA PF08288.7 EFI26801.1 - 2.8e-37 126.9 0.2 8.3e-37 125.4 0.1 1.9 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EFI26801.1 - 7e-28 97.1 0.0 1.1e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EFI26801.1 - 2.1e-13 50.5 0.0 4.1e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EFI26801.1 - 5.5e-09 35.9 0.3 3e-08 33.5 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EFI26801.1 - 6.5e-08 32.8 0.1 1.8e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EFI26801.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DAO PF01266.19 EFI26802.1 - 3.5e-19 68.9 1.7 2e-18 66.4 1.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GST_N_2 PF13409.1 EFI26802.1 - 0.057 13.4 0.0 4.1 7.4 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain NAD_binding_8 PF13450.1 EFI26802.1 - 0.083 12.9 5.5 0.14 12.2 0.6 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain ChAPs PF09295.5 EFI26804.1 - 3.4e-107 358.6 3.8 2e-95 319.8 0.1 3.3 3 0 0 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EFI26804.1 - 6.7e-06 25.6 0.1 0.032 13.8 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 EFI26804.1 - 1.3e-05 25.6 0.0 0.045 14.4 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EFI26804.1 - 1.7e-05 25.0 0.6 0.00079 19.7 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EFI26804.1 - 0.0002 21.0 5.5 6.7 6.9 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EFI26804.1 - 0.00047 20.0 0.3 6.8 6.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EFI26804.1 - 0.0017 18.0 0.6 0.8 9.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EFI26804.1 - 0.0028 18.1 4.3 15 6.5 0.0 6.0 4 2 3 7 7 7 1 Tetratricopeptide repeat ChAPs PF09295.5 EFI26806.1 - 5.5e-149 496.2 0.0 7.3e-147 489.2 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EFI26806.1 - 5.6e-08 32.3 0.3 0.00049 19.6 0.0 3.7 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.1 EFI26806.1 - 1.5e-07 31.8 0.0 0.029 15.0 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EFI26806.1 - 3.1e-07 30.6 2.0 0.00051 20.3 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EFI26806.1 - 8.5e-07 28.4 3.8 4.4 7.4 0.2 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EFI26806.1 - 1.7e-06 27.8 0.4 0.084 12.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EFI26806.1 - 1.3e-05 24.6 0.7 0.53 10.2 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EFI26806.1 - 6.4e-05 23.2 8.7 11 6.9 0.0 7.7 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EFI26806.1 - 0.0054 16.4 1.1 5.7 7.0 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EFI26806.1 - 0.035 12.8 0.1 0.77 8.4 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 BTAD PF03704.12 EFI26806.1 - 0.062 13.5 2.1 0.53 10.5 0.0 3.1 4 0 0 4 4 3 0 Bacterial transcriptional activator domain TPR_1 PF00515.23 EFI26806.1 - 0.12 11.9 6.8 37 4.1 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat F-box PF00646.28 EFI26808.1 - 3.4e-13 48.8 7.0 5e-06 26.0 0.4 2.7 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 EFI26808.1 - 4e-09 36.0 10.5 0.00034 20.2 1.3 3.0 2 0 0 2 2 2 2 F-box-like OKR_DC_1_C PF03711.10 EFI26808.1 - 0.011 15.7 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain hEGF PF12661.2 EFI26808.1 - 0.23 11.6 6.9 7.3 6.9 0.5 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF p450 PF00067.17 EFI26809.1 - 1.1e-65 221.9 0.0 1.6e-48 165.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TPMT PF05724.6 EFI26810.1 - 9.5e-33 113.4 0.0 1.1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EFI26810.1 - 2.3e-09 37.7 0.0 4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI26810.1 - 8.5e-09 35.1 0.0 1.1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EFI26810.1 - 1.4e-08 34.8 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EFI26810.1 - 1e-07 32.3 0.0 1.4e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EFI26810.1 - 2.9e-07 30.8 0.0 5.5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EFI26810.1 - 4.8e-07 30.0 0.0 6.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EFI26810.1 - 1.5e-05 24.8 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EFI26810.1 - 0.021 13.9 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB LRR_4 PF12799.2 EFI26811.1 - 0.015 14.8 0.1 1.7 8.3 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EFI26811.1 - 0.025 14.2 1.1 0.065 12.9 0.1 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EFI26811.1 - 0.064 12.9 0.1 0.064 12.9 0.1 2.5 3 0 0 3 3 3 0 F-box domain Epimerase PF01370.16 EFI26813.1 - 3.8e-33 114.8 0.0 6.2e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glycos_transf_2 PF00535.21 EFI26813.1 - 6.1e-14 52.0 0.4 1.6e-13 50.7 0.1 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EFI26813.1 - 1.1e-10 41.7 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 3Beta_HSD PF01073.14 EFI26813.1 - 1.4e-10 40.3 0.0 2.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EFI26813.1 - 3.3e-08 32.7 0.0 5.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EFI26813.1 - 4.5e-05 23.5 0.0 8.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Glyco_tranf_2_2 PF10111.4 EFI26813.1 - 7.6e-05 21.9 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Polysacc_synt_2 PF02719.10 EFI26813.1 - 0.00016 20.6 0.0 0.00037 19.4 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EFI26813.1 - 0.03 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_tranf_2_5 PF13712.1 EFI26813.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family NmrA PF05368.8 EFI26813.1 - 0.2 10.8 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family HLH PF00010.21 EFI26814.1 - 1.1e-19 69.8 0.0 3.8e-19 68.1 0.0 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain DEAD PF00270.24 EFI26818.1 - 8.5e-16 57.9 0.0 1.9e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EFI26818.1 - 5e-08 32.6 0.0 0.00054 19.7 0.0 3.3 2 1 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EFI26818.1 - 1.2e-05 25.0 0.4 7.7e-05 22.3 0.3 2.2 1 1 0 1 1 1 1 RQC domain Guanylate_cyc_2 PF09778.4 EFI26822.1 - 0.061 12.4 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Guanylylate cyclase H_lectin PF09458.5 EFI26824.1 - 4.5e-34 115.9 0.1 2.9e-13 49.2 0.0 4.1 4 0 0 4 4 4 3 H-type lectin domain Fumarate_red_C PF02300.12 EFI26828.1 - 0.027 14.3 0.7 0.094 12.5 0.5 2.0 1 1 0 1 1 1 0 Fumarate reductase subunit C DUF3995 PF13160.1 EFI26829.1 - 0.069 13.1 0.3 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) PHD PF00628.24 EFI26830.1 - 1.1e-07 31.4 10.4 2.1e-07 30.5 7.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EFI26830.1 - 2.7 7.3 7.9 5.2 6.4 5.5 1.5 1 0 0 1 1 1 0 PHD-finger CFEM PF05730.6 EFI26831.1 - 5.8e-05 22.8 6.9 8.1e-05 22.3 4.8 1.2 1 0 0 1 1 1 1 CFEM domain HpaP PF09483.5 EFI26831.1 - 0.15 12.0 4.5 0.18 11.7 3.1 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) zf-MYND PF01753.13 EFI26834.1 - 2.3e-09 36.9 10.2 4.7e-09 35.9 7.1 1.5 1 0 0 1 1 1 1 MYND finger DUF2421 PF10334.4 EFI26834.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) Hydrophobin PF01185.13 EFI26839.1 - 6.3e-06 26.5 0.1 9.1e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Fungal hydrophobin DUF1996 PF09362.5 EFI26842.1 - 2.7e-68 230.1 0.0 3.3e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EFI26843.1 - 0.00071 19.3 0.1 0.00091 18.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NAD_binding_4 PF07993.7 EFI26844.1 - 1.3e-29 102.9 0.0 2.2e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein ABA_GPCR PF12430.3 EFI26844.1 - 1.7e-17 63.1 0.8 3e-17 62.4 0.5 1.3 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor Epimerase PF01370.16 EFI26844.1 - 8.3e-09 35.2 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EFI26844.1 - 0.0019 16.9 0.0 0.018 13.7 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EFI26844.1 - 0.0068 15.3 0.1 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Peptidase_C33 PF05412.7 EFI26844.1 - 0.034 13.9 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase F-protein PF00469.15 EFI26844.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef ACOX PF01756.14 EFI26847.1 - 3.2e-31 108.1 0.0 9.3e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EFI26847.1 - 9.8e-20 71.1 0.1 2.4e-19 69.8 0.1 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EFI26847.1 - 4.4e-08 32.5 0.9 9.5e-08 31.4 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EFI26847.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain APH PF01636.18 EFI26848.1 - 2.3e-10 40.6 0.0 1.9e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EFI26848.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase F-box PF00646.28 EFI26849.1 - 1.2e-06 28.0 1.1 3.7e-06 26.4 0.8 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EFI26849.1 - 0.00014 21.5 0.2 0.00038 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EFI26849.1 - 0.00086 19.0 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain MFS_1 PF07690.11 EFI26850.1 - 1.1e-20 73.7 11.5 2.5e-20 72.4 8.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily THDPS_N_2 PF14805.1 EFI26852.1 - 0.019 14.8 0.1 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Zea_mays_MuDR PF05928.6 EFI26852.1 - 0.063 12.6 0.0 10 5.5 0.0 2.3 2 1 0 2 2 2 0 Zea mays MURB-like protein (MuDR) Glyco_hydro_62 PF03664.8 EFI26857.1 - 1.6e-71 240.6 2.9 2e-71 240.3 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 EFI26857.1 - 5.4e-07 29.1 5.5 7.4e-05 22.3 0.5 2.7 2 0 0 2 2 2 2 Fungal cellulose binding domain ADAM_CR PF08516.7 EFI26860.1 - 0.059 13.4 0.4 0.17 11.9 0.0 1.9 1 1 1 2 2 2 0 ADAM cysteine-rich Peptidase_M43 PF05572.8 EFI26865.1 - 1.7e-18 66.6 0.0 2.5e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EFI26865.1 - 1.9e-06 27.9 0.1 4.9e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EFI26865.1 - 1.1e-05 26.0 0.4 9.8e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EFI26865.1 - 1.9e-05 24.7 1.2 3.1e-05 24.1 0.8 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EFI26865.1 - 0.003 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EFI26865.1 - 0.0038 16.5 0.5 0.0071 15.6 0.1 1.6 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 EFI26865.1 - 0.019 13.8 0.6 0.03 13.2 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.19 EFI26865.1 - 0.031 14.0 0.1 0.046 13.4 0.1 1.5 1 1 0 1 1 1 0 Matrixin DUF3748 PF12566.3 EFI26868.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) TPR_11 PF13414.1 EFI26870.1 - 5.4e-11 41.9 1.0 0.00013 21.5 0.0 3.0 1 1 2 3 3 3 2 TPR repeat TPR_2 PF07719.12 EFI26870.1 - 9.9e-11 40.7 1.7 0.026 14.4 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EFI26870.1 - 1.3e-10 40.3 0.2 0.028 14.0 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EFI26870.1 - 7.6e-08 32.1 4.0 0.0003 20.6 0.2 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EFI26870.1 - 3.2e-07 30.8 3.0 2.8e-05 24.6 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EFI26870.1 - 4.1e-06 26.1 5.8 0.38 10.6 0.1 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EFI26870.1 - 1.7e-05 24.6 0.0 0.095 12.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EFI26870.1 - 5.4e-05 23.4 10.1 0.14 12.8 0.1 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EFI26870.1 - 0.00012 21.5 0.0 1.4 8.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EFI26870.1 - 0.0003 21.0 6.1 0.55 10.5 0.0 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EFI26870.1 - 0.0014 18.9 1.7 5.9 7.5 0.0 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.13 EFI26870.1 - 0.023 14.5 0.8 8.1 6.4 0.0 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain HEAT_PBS PF03130.11 EFI26870.1 - 0.045 14.2 2.3 25 5.7 0.3 3.6 2 1 0 2 2 2 0 PBS lyase HEAT-like repeat Apc3 PF12895.2 EFI26870.1 - 0.055 13.6 0.0 3.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EFI26870.1 - 0.089 12.7 15.2 5.4 7.0 0.0 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EFI26870.1 - 0.52 9.6 5.3 42 3.5 0.0 3.9 4 0 0 4 4 4 0 SHNi-TPR UCH PF00443.24 EFI26871.1 - 7.3e-43 146.6 0.0 9.4e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EFI26871.1 - 1e-17 64.5 0.0 2.1e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EFI26871.1 - 5.5e-05 22.4 0.0 0.00015 21.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EFI26871.1 - 0.082 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain RRM_1 PF00076.17 EFI26874.1 - 2.7e-13 49.3 0.0 3.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI26874.1 - 3.7e-09 36.4 0.0 5.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI26874.1 - 7.3e-07 28.9 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EFI26874.1 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3552 PF12072.3 EFI26874.1 - 6.5 5.9 9.6 8.4 5.5 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Acetyltransf_8 PF13523.1 EFI26875.1 - 8.7e-40 136.0 0.1 1.4e-39 135.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EFI26875.1 - 6.3e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Helitron_like_N PF14214.1 EFI26879.1 - 1.8e-10 40.8 0.0 7.4e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF202 PF02656.10 EFI26882.1 - 0.0025 17.9 4.0 0.0025 17.9 2.8 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF202) MFS_1 PF07690.11 EFI26882.1 - 0.008 14.9 0.3 0.01 14.5 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2721 PF11026.3 EFI26882.1 - 0.018 14.6 0.2 0.018 14.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MadL PF03817.8 EFI26882.1 - 0.042 13.7 0.2 0.086 12.6 0.2 1.5 1 0 0 1 1 1 0 Malonate transporter MadL subunit Claudin_2 PF13903.1 EFI26882.1 - 0.093 12.4 0.2 0.24 11.0 0.1 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction VPEP PF07589.6 EFI26882.1 - 0.92 9.4 5.1 3.9 7.5 3.5 2.1 1 0 0 1 1 1 0 PEP-CTERM motif SdpI PF13630.1 EFI26882.1 - 1.7 8.3 6.5 6 6.6 1.8 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family zf-CCHC PF00098.18 EFI26884.1 - 1.1e-09 37.6 3.1 0.0011 18.8 0.2 2.7 2 0 0 2 2 2 2 Zinc knuckle Asp_protease_2 PF13650.1 EFI26884.1 - 2.1e-08 34.5 0.0 0.0029 18.0 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease zf-CCHC_6 PF15288.1 EFI26884.1 - 6.9e-05 22.4 5.6 0.12 12.0 0.4 2.5 2 0 0 2 2 2 2 Zinc knuckle RVP_2 PF08284.6 EFI26884.1 - 0.00014 21.8 0.1 0.014 15.2 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF4414 PF14377.1 EFI26884.1 - 0.00058 19.7 0.2 1.1 9.2 0.0 3.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) DZR PF12773.2 EFI26884.1 - 0.079 12.7 3.4 7 6.5 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF3603 PF12227.3 EFI26884.1 - 0.13 11.4 0.5 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) zf-CCHC_4 PF14392.1 EFI26884.1 - 3.7 7.2 4.4 35 4.1 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle COX16 PF14138.1 EFI26885.1 - 0.071 13.2 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Microtub_assoc PF07989.6 EFI26886.1 - 5.6e-21 74.1 11.7 5.6e-21 74.1 8.1 11.3 9 4 2 13 13 13 1 Microtubule associated DUF3584 PF12128.3 EFI26886.1 - 8.1e-06 23.4 56.9 8.1e-06 23.4 39.4 3.7 2 1 0 3 3 3 2 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EFI26886.1 - 6.8e-05 21.5 112.4 0.0028 16.2 13.0 5.6 2 1 4 6 6 6 4 AAA domain GAS PF13851.1 EFI26886.1 - 0.0023 17.1 17.4 0.0023 17.1 12.0 8.1 3 3 4 8 8 8 3 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 EFI26886.1 - 0.003 17.4 0.9 0.003 17.4 0.6 15.1 10 6 7 18 18 18 2 bZIP transcription factor Mto2_bdg PF12808.2 EFI26886.1 - 0.0067 16.5 11.3 0.0067 16.5 7.8 14.1 13 3 1 14 14 14 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 EFI26886.1 - 0.0084 15.3 47.7 0.11 11.5 1.4 7.5 3 2 5 9 9 9 5 Reovirus sigma C capsid protein Flavodoxin_1 PF00258.20 EFI26889.1 - 1.8e-29 102.5 0.0 2.8e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EFI26889.1 - 3.7e-22 78.8 0.1 1.6e-16 60.4 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Flavodoxin_5 PF12724.2 EFI26889.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin domain TPR_11 PF13414.1 EFI26890.1 - 1e-11 44.3 0.1 1.9e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 TPR repeat DUF4470 PF14737.1 EFI26890.1 - 2.3e-10 40.0 0.0 4.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_2 PF07719.12 EFI26890.1 - 0.053 13.4 0.4 0.5 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SUI1 PF01253.17 EFI26892.1 - 1.1e-09 37.9 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 EFI26892.1 - 0.00041 20.0 0.0 0.00085 19.0 0.0 1.6 1 0 0 1 1 1 1 PUA domain SWIB PF02201.13 EFI26892.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain PAP_assoc PF03828.14 EFI26896.1 - 8e-14 51.3 0.2 1.8e-13 50.2 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EFI26896.1 - 1.7e-05 25.0 0.0 3.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIA PF03153.8 EFI26897.1 - 2.4 7.9 12.0 2.9 7.7 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.1 EFI26898.1 - 1e-09 38.1 10.1 6.3e-08 32.5 0.2 3.2 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EFI26898.1 - 2.8e-08 33.5 8.0 0.00021 21.4 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EFI26898.1 - 1.7e-05 24.8 9.7 0.017 15.4 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EFI26898.1 - 0.021 14.9 2.1 0.021 14.9 1.4 2.3 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 EFI26898.1 - 0.13 12.1 2.4 0.28 11.0 1.7 1.6 1 1 0 1 1 1 0 IBR domain zf-C2HC_2 PF13913.1 EFI26898.1 - 0.14 11.8 0.6 0.38 10.4 0.4 1.9 1 1 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EFI26898.1 - 0.15 12.0 0.4 0.15 12.0 0.3 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EFI26898.1 - 0.31 11.3 4.8 3.5 8.0 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Sina PF03145.11 EFI26898.1 - 0.4 10.3 2.9 0.62 9.6 2.0 1.2 1 0 0 1 1 1 0 Seven in absentia protein family NADH-G_4Fe-4S_3 PF10588.4 EFI26898.1 - 0.4 9.9 1.9 0.81 8.9 1.3 1.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Gp_dh_N PF00044.19 EFI26902.1 - 0.00019 21.4 0.1 0.00028 20.8 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pkinase PF00069.20 EFI26903.1 - 1.1e-36 126.3 0.0 2.3e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI26903.1 - 7.6e-27 93.9 0.0 1.5e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EFI26903.1 - 1.9e-06 28.1 0.2 1.1e-05 25.7 0.1 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EFI26903.1 - 1.4e-05 24.1 0.0 2.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EFI26903.1 - 0.17 10.7 0.1 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Asp_protease_2 PF13650.1 EFI26905.1 - 0.023 15.1 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease SAP PF02037.22 EFI26909.1 - 6.6e-06 25.4 0.4 1.1e-05 24.7 0.3 1.4 1 0 0 1 1 1 1 SAP domain Rft-1 PF04506.8 EFI26910.1 - 2.8e-84 283.4 6.6 3.6e-84 283.1 4.6 1.2 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.1 EFI26910.1 - 3.9e-05 23.2 5.0 3.9e-05 23.2 3.5 3.6 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein MAD PF05557.8 EFI26913.1 - 0.022 12.8 4.3 0.032 12.3 3.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein AIG1 PF04548.11 EFI26917.1 - 0.0055 15.8 3.4 0.053 12.6 0.0 2.6 1 1 2 3 3 3 1 AIG1 family TMF_TATA_bd PF12325.3 EFI26917.1 - 0.014 15.1 1.5 0.026 14.2 1.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MMR_HSR1 PF01926.18 EFI26917.1 - 0.034 14.1 0.0 0.079 12.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EFI26917.1 - 0.067 12.6 0.1 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HSP70 PF00012.15 EFI26918.1 - 0.00082 17.4 0.0 0.57 8.0 0.0 2.4 2 1 0 2 2 2 2 Hsp70 protein Baculo_DNA_bind PF04786.7 EFI26918.1 - 0.0044 16.1 0.1 0.0066 15.6 0.1 1.2 1 0 0 1 1 1 1 ssDNA binding protein Peptidase_M22 PF00814.20 EFI26918.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family DUF1052 PF06319.7 EFI26918.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1052) Rap_GAP PF02145.10 EFI26920.1 - 5.2e-47 159.6 0.0 9e-47 158.8 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EFI26920.1 - 1e-25 90.6 0.8 1.7e-25 89.8 0.1 1.6 2 0 0 2 2 2 1 Tuberin Ank_2 PF12796.2 EFI26923.1 - 2.2e-38 130.4 0.2 2e-12 47.2 0.0 4.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EFI26923.1 - 5e-33 111.2 4.2 1.1e-05 24.9 0.0 7.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 EFI26923.1 - 3.6e-30 103.2 3.1 2.9e-08 33.6 0.1 5.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EFI26923.1 - 2.1e-25 88.5 0.0 1.1e-07 32.1 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EFI26923.1 - 5.6e-21 72.5 0.0 0.0067 16.5 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Got1 PF04178.7 EFI26924.1 - 5.4e-12 45.8 0.5 1.7e-09 37.8 0.1 2.0 1 1 1 2 2 2 2 Got1/Sft2-like family DUF4179 PF13786.1 EFI26925.1 - 0.14 12.4 0.4 0.26 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Dicty_REP PF05086.7 EFI26925.1 - 1 7.0 4.8 0.088 10.5 0.2 1.4 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Plasmodium_Vir PF05795.6 EFI26925.1 - 5 6.2 9.7 8.3 5.5 6.2 1.6 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF2363 PF10155.4 EFI26928.1 - 8.9e-08 32.1 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) PQQ_2 PF13360.1 EFI26931.1 - 3.7e-17 62.5 7.3 2.4e-07 30.4 0.2 3.4 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 EFI26931.1 - 6.3e-09 34.9 4.1 0.00021 20.6 0.0 4.9 6 0 0 6 6 6 2 PQQ enzyme repeat DUF1620 PF07774.8 EFI26932.1 - 5.7e-61 205.5 0.0 7.1e-61 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) FRQ PF09421.5 EFI26932.1 - 0.068 10.9 0.0 0.091 10.5 0.0 1.1 1 0 0 1 1 1 0 Frequency clock protein COG6 PF06419.6 EFI26934.1 - 4.6e-151 504.0 0.7 6.7e-151 503.4 0.5 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Laminin_I PF06008.9 EFI26934.1 - 0.0032 16.8 6.8 0.0076 15.5 4.7 1.6 1 0 0 1 1 1 1 Laminin Domain I NPV_P10 PF05531.7 EFI26934.1 - 0.084 13.1 0.9 0.95 9.7 0.5 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TFIIA PF03153.8 EFI26934.1 - 1.5 8.6 11.2 0.52 10.1 2.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 EFI26934.1 - 4.7 6.2 19.5 0.011 14.8 5.4 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Peptidase_S9 PF00326.16 EFI26935.1 - 1.6e-27 96.1 0.0 1.7e-15 56.8 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EFI26935.1 - 5.9e-13 49.2 1.2 1.1e-12 48.3 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EFI26935.1 - 5.3e-10 39.2 0.1 2.4e-09 37.0 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EFI26935.1 - 2.8e-05 23.8 0.0 6.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EFI26935.1 - 0.0004 20.0 0.0 0.0013 18.3 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EFI26935.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EFI26935.1 - 0.22 10.9 0.0 7.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase STE3 PF02076.10 EFI26937.1 - 2.4e-99 332.0 16.0 2.9e-99 331.7 11.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EFI26938.1 - 5.3e-76 255.4 8.9 6.2e-76 255.1 6.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.6 EFI26940.1 - 6.4e-15 55.7 0.6 7.1e-15 55.6 0.4 1.0 1 0 0 1 1 1 1 Fungal mating-type pheromone MFS_1 PF07690.11 EFI26941.1 - 5.3e-20 71.4 35.2 9.5e-11 40.9 4.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EFI26941.1 - 1e-13 50.7 16.2 4.2e-12 45.3 4.3 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EFI26942.1 - 3.4e-22 78.6 47.4 9.1e-20 70.6 20.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EFI26942.1 - 1.2e-14 53.8 15.3 2.2e-14 52.9 10.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1708 PF08101.6 EFI26947.1 - 4.7e-15 55.3 0.0 1.7e-14 53.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 EFI26947.1 - 0.0013 18.3 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M43 PF05572.8 EFI26949.1 - 6.3e-19 68.0 0.0 8.8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EFI26949.1 - 6.7e-07 29.4 0.0 1.4e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EFI26949.1 - 1.3e-05 25.3 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EFI26949.1 - 1.6e-05 25.3 0.0 2.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EFI26949.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EFI26949.1 - 0.01 15.1 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EFI26949.1 - 0.048 13.3 0.1 0.065 12.9 0.1 1.4 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 EFI26949.1 - 0.067 12.0 0.7 0.1 11.4 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M7 PF02031.11 EFI26949.1 - 0.073 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M43 PF05572.8 EFI26950.1 - 1.4e-18 66.9 0.0 2.3e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EFI26950.1 - 2.3e-07 30.9 0.0 3.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EFI26950.1 - 3.8e-06 27.4 0.0 6.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EFI26950.1 - 8.7e-05 21.9 0.1 0.00013 21.3 0.1 1.2 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_2 PF13574.1 EFI26950.1 - 0.00015 21.8 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EFI26950.1 - 0.0042 16.6 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EFI26950.1 - 0.016 14.9 0.1 0.026 14.2 0.0 1.3 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 EFI26950.1 - 0.074 11.9 0.5 0.11 11.3 0.3 1.2 1 0 0 1 1 1 0 Peptidase M66 zf-C2H2 PF00096.21 EFI26951.1 - 0.0015 18.7 0.3 0.0015 18.7 0.2 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EFI26951.1 - 0.18 12.1 2.2 1.7 9.1 0.5 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Helicase_C_2 PF13307.1 EFI26952.1 - 0.096 12.6 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain KcnmB2_inactiv PF09303.5 EFI26958.1 - 0.47 10.2 3.2 0.49 10.2 1.3 1.8 2 0 0 2 2 2 0 KCNMB2, ball and chain domain ENOD40 PF08247.6 EFI26959.1 - 7.9 6.5 7.0 14 5.7 1.0 2.5 2 0 0 2 2 2 0 ENOD40 protein DUF4071 PF13281.1 EFI26962.1 - 0.4 9.4 2.2 0.63 8.8 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) MarC PF01914.12 EFI26963.1 - 1.6 7.8 3.2 2.5 7.1 2.2 1.3 1 0 0 1 1 1 0 MarC family integral membrane protein Cauli_AT PF03233.8 EFI26968.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Aphid transmission protein Pro-MCH PF05824.7 EFI26969.1 - 0.096 12.1 0.0 9.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) Peptidase_C14 PF00656.17 EFI26977.1 - 1.6e-12 47.7 0.0 3.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Caspase domain Pkinase PF00069.20 EFI26983.1 - 2.3e-05 23.6 0.0 4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3386 PF11866.3 EFI26984.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3386) Pkinase PF00069.20 EFI26986.1 - 6.7e-07 28.7 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EFI26989.1 - 3.7e-07 29.5 0.0 6.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI26989.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EFI26991.1 - 0.0022 17.1 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EFI26992.1 - 1.4e-07 30.9 0.0 2.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EFI26993.1 - 3.7e-05 22.9 0.0 7.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF791 PF05631.9 EFI26999.1 - 2.5e-66 223.7 4.5 3.5e-66 223.2 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EFI26999.1 - 2.4e-20 72.5 28.5 3.4e-20 72.0 19.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PCMT PF01135.14 EFI27000.1 - 7.2e-74 247.8 0.0 8.5e-74 247.6 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EFI27000.1 - 4e-10 40.2 0.0 6.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EFI27000.1 - 7.8e-07 29.1 0.0 1.7e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI27000.1 - 9.7e-07 28.4 0.0 4.1e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EFI27000.1 - 2.3e-06 27.4 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EFI27000.1 - 0.00064 19.4 0.0 0.00098 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EFI27000.1 - 0.0036 17.7 0.0 0.0074 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EFI27000.1 - 0.0057 16.1 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 EFI27000.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 EFI27000.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 EFI27000.1 - 0.11 11.6 0.0 0.24 10.4 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EFI27000.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EFI27000.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pkinase PF00069.20 EFI27001.1 - 1.5e-05 24.2 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EFI27002.1 - 1.5e-06 27.5 0.0 2.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27002.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EFI27005.1 - 4.5e-05 22.7 0.0 8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EFI27006.1 - 4.5e-07 29.2 0.0 7.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RabGAP-TBC PF00566.13 EFI27009.1 - 2.4e-05 23.9 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box PF00646.28 EFI27011.1 - 4.6e-05 22.9 3.0 0.00013 21.5 0.5 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EFI27011.1 - 0.00033 20.3 0.1 0.00069 19.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like Peptidase_S28 PF05577.7 EFI27013.1 - 1.8e-16 59.7 14.5 3.5e-08 32.4 0.0 4.9 3 2 1 5 5 5 4 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EFI27013.1 - 0.00018 20.8 0.1 0.00031 20.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BMP2K_C PF15282.1 EFI27015.1 - 0.0037 17.4 0.1 0.0049 17.0 0.0 1.1 1 0 0 1 1 1 1 BMP-2-inducible protein kinase C-terminus Acetyltransf_3 PF13302.1 EFI27016.1 - 5.3e-17 62.2 0.0 6.9e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EFI27016.1 - 5.5e-06 26.3 0.0 5.1e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EFI27016.1 - 8.3e-05 22.2 0.0 0.0028 17.3 0.0 2.2 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 EFI27016.1 - 0.00037 20.3 0.0 0.79 9.5 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EFI27016.1 - 0.045 13.9 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EFI27016.1 - 0.073 13.0 0.0 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_C14 PF00656.17 EFI27017.1 - 5.1e-14 52.5 0.0 7.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Aminotran_1_2 PF00155.16 EFI27018.1 - 7.4e-11 41.5 0.0 1.3e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DSPc PF00782.15 EFI27019.1 - 5.2e-29 100.4 0.0 7.9e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EFI27019.1 - 7.8e-05 22.1 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EFI27019.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EFI27019.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Chorion_2 PF03964.10 EFI27019.1 - 0.15 12.6 3.6 0.87 10.1 0.2 2.6 2 0 0 2 2 2 0 Chorion family 2 zinc_ribbon_5 PF13719.1 EFI27019.1 - 1.6 8.3 4.3 1.9 8.1 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EFI27019.1 - 2.4 7.8 5.0 2.2 8.0 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain KaiB PF07689.7 EFI27021.1 - 0.063 12.7 0.1 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 KaiB domain DUF3319 PF11782.3 EFI27021.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) DUF1331 PF07048.6 EFI27021.1 - 0.13 11.6 0.1 0.3 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Filament PF00038.16 EFI27024.1 - 4.8e-05 22.9 2.4 4.8e-05 22.9 1.7 2.2 1 1 1 2 2 2 1 Intermediate filament protein Reo_sigmaC PF04582.7 EFI27024.1 - 0.00053 19.2 0.4 0.0033 16.6 0.0 1.9 1 1 1 2 2 2 1 Reovirus sigma C capsid protein EzrA PF06160.7 EFI27024.1 - 0.00055 18.2 7.8 0.0011 17.2 5.1 1.7 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA IncA PF04156.9 EFI27024.1 - 0.0016 18.0 3.2 0.0016 18.0 2.2 3.1 2 1 1 3 3 3 1 IncA protein COG2 PF06148.6 EFI27024.1 - 0.0017 18.2 5.3 0.0019 18.0 0.1 3.0 1 1 2 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 EFI27024.1 - 0.003 17.1 2.0 0.003 17.1 1.4 2.6 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 EFI27024.1 - 0.0041 16.9 6.3 0.012 15.4 0.2 3.4 1 1 3 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.7 EFI27024.1 - 0.0054 16.4 1.6 0.0054 16.4 1.1 3.2 2 2 1 3 3 3 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EFI27024.1 - 0.043 13.6 3.9 1.1 9.0 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG5 PF10392.4 EFI27024.1 - 0.055 13.4 1.5 3.5 7.5 0.0 3.6 1 1 3 4 4 4 0 Golgi transport complex subunit 5 Bacillus_HBL PF05791.6 EFI27024.1 - 0.1 11.9 2.2 0.36 10.1 0.1 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Med9 PF07544.8 EFI27024.1 - 0.13 11.9 5.0 0.092 12.4 0.4 2.8 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.6 EFI27024.1 - 0.16 11.8 5.1 1.4 8.8 0.0 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FH2 PF02181.18 EFI27024.1 - 0.28 10.0 6.1 0.29 9.9 0.6 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF2730 PF10805.3 EFI27024.1 - 0.29 10.8 4.5 0.55 9.9 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.14 EFI27024.1 - 0.38 8.5 3.6 0.65 7.7 2.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.6 EFI27024.1 - 0.5 7.8 1.1 0.83 7.1 0.8 1.3 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.7 EFI27024.1 - 0.54 10.0 5.6 1.8 8.3 0.7 2.7 1 1 1 2 2 2 0 Laminin Domain II Mitofilin PF09731.4 EFI27024.1 - 0.7 8.4 27.3 2.8 6.5 18.8 2.0 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Atg14 PF10186.4 EFI27024.1 - 0.81 8.5 4.5 1 8.2 2.2 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NPV_P10 PF05531.7 EFI27024.1 - 0.86 9.9 7.8 0.95 9.7 0.1 4.1 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Hemagglutinin PF00509.13 EFI27024.1 - 1.2 7.1 3.2 0.9 7.5 0.2 2.1 2 1 1 3 3 3 0 Haemagglutinin AAA_13 PF13166.1 EFI27024.1 - 1.9 6.8 15.6 0.0062 15.0 3.6 2.1 2 1 0 2 2 1 0 AAA domain Fzo_mitofusin PF04799.8 EFI27024.1 - 1.9 7.8 5.5 1.2 8.4 0.8 2.5 3 0 0 3 3 2 0 fzo-like conserved region Fib_alpha PF08702.5 EFI27024.1 - 1.9 8.6 6.5 6.8 6.8 2.3 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family LINES_C PF14695.1 EFI27026.1 - 0.015 14.4 0.5 0.05 12.8 0.1 2.0 2 0 0 2 2 2 0 Lines C-terminus CobN-Mg_chel PF02514.11 EFI27026.1 - 2.3 5.4 4.7 3.1 5.0 3.2 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Seryl_tRNA_N PF02403.17 EFI27028.1 - 0.015 15.2 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1192 PF06698.6 EFI27028.1 - 0.062 13.1 0.7 0.1 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Utp12 PF04003.7 EFI27028.1 - 0.11 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Dip2/Utp12 Family Ferric_reduct PF01794.14 EFI27032.1 - 4e-20 72.1 3.0 4e-20 72.1 2.1 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EFI27032.1 - 2.1e-10 40.4 0.0 4.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EFI27032.1 - 3.5e-09 36.7 0.0 1.1e-08 35.0 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ni_hydr_CYTB PF01292.15 EFI27032.1 - 0.84 8.9 5.7 0.98 8.7 0.2 2.3 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4181 PF13789.1 EFI27032.1 - 2.4 8.1 7.5 38 4.2 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) p450 PF00067.17 EFI27033.1 - 1.3e-31 109.6 0.0 6.1e-11 41.4 0.0 3.1 2 1 1 3 3 3 3 Cytochrome P450 XH PF03469.9 EFI27034.1 - 0.009 15.6 1.9 0.01 15.4 0.1 1.9 2 0 0 2 2 2 1 XH domain Menin PF05053.8 EFI27034.1 - 0.096 10.8 3.0 0.11 10.6 2.1 1.1 1 0 0 1 1 1 0 Menin FAA_hydrolase PF01557.13 EFI27036.1 - 5.4e-06 26.0 0.1 7.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PNRC PF15365.1 EFI27040.1 - 0.023 14.6 0.3 0.023 14.6 0.2 2.6 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator Cyclin PF08613.6 EFI27043.1 - 0.015 15.6 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin Pkinase_Tyr PF07714.12 EFI27044.1 - 5.6e-34 117.3 0.0 8.8e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EFI27044.1 - 4.5e-33 114.5 0.0 7.3e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MMR_HSR1 PF01926.18 EFI27044.1 - 3.3e-09 36.7 0.0 1.3e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EFI27044.1 - 1.2e-07 31.1 0.0 1.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EFI27044.1 - 3.9e-05 23.5 0.0 0.042 13.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 EFI27044.1 - 4.3e-05 22.7 0.0 9.7e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 APH PF01636.18 EFI27044.1 - 0.00015 21.5 0.6 0.00096 18.9 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Septin PF00735.13 EFI27044.1 - 0.0059 15.6 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 EFI27044.1 - 0.0061 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EFI27044.1 - 0.016 14.7 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EFI27044.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.8 EFI27044.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 EFI27044.1 - 0.026 14.6 0.0 0.073 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain GBP PF02263.14 EFI27044.1 - 0.028 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_33 PF13671.1 EFI27044.1 - 0.038 13.8 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EFI27044.1 - 0.051 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EFI27044.1 - 0.058 13.3 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain ABC1 PF03109.11 EFI27044.1 - 0.091 12.7 0.0 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 ABC1 family AAA_10 PF12846.2 EFI27044.1 - 0.095 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EFI27044.1 - 0.11 12.8 0.1 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.10 EFI27044.1 - 0.14 10.7 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_17 PF13207.1 EFI27044.1 - 0.49 11.2 1.7 0.75 10.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 EFI27045.1 - 5.8e-27 94.4 0.0 2.8e-26 92.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27045.1 - 4.2e-20 71.8 0.0 5.6e-19 68.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AIG1 PF04548.11 EFI27045.1 - 6e-11 41.8 0.0 8.9e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EFI27045.1 - 2.2e-07 30.8 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EFI27045.1 - 2.5e-06 26.7 0.0 5.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EFI27045.1 - 7.1e-05 22.6 0.1 0.1 12.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family GBP PF02263.14 EFI27045.1 - 0.00038 19.6 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain IstB_IS21 PF01695.12 EFI27045.1 - 0.0011 18.4 0.0 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein IIGP PF05049.8 EFI27045.1 - 0.0054 15.5 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EFI27045.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Septin PF00735.13 EFI27045.1 - 0.033 13.2 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_33 PF13671.1 EFI27045.1 - 0.033 14.0 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EFI27045.1 - 0.045 13.2 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EFI27045.1 - 0.05 13.0 0.5 2.9 7.2 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 EFI27045.1 - 0.12 12.7 0.1 0.2 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Spore_IV_A PF09547.5 EFI27045.1 - 0.16 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) T2SE PF00437.15 EFI27045.1 - 0.18 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 EFI27045.1 - 0.18 12.6 2.0 1 10.2 0.2 2.9 3 1 0 3 3 3 0 AAA domain MAPEG PF01124.13 EFI27052.1 - 1.5e-14 53.6 2.5 1.9e-14 53.3 1.7 1.2 1 0 0 1 1 1 1 MAPEG family Methyltransf_16 PF10294.4 EFI27055.1 - 2.3e-10 40.1 0.0 2.9e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Gag_p10 PF02337.12 EFI27057.1 - 0.043 13.5 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein PCI PF01399.22 EFI27059.1 - 9.3e-24 83.7 0.3 1.4e-22 79.9 0.0 3.0 5 0 0 5 5 5 1 PCI domain Rpn3_C PF08375.6 EFI27059.1 - 3e-17 62.7 6.9 5.5e-17 61.9 0.1 3.0 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 EFI27059.1 - 0.0022 17.7 0.9 0.043 13.7 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EFI27059.1 - 0.0061 16.3 0.2 0.88 9.3 0.0 2.6 2 0 0 2 2 2 2 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EFI27059.1 - 1.8 8.5 13.9 4 7.4 0.3 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat Myc_N PF01056.13 EFI27060.1 - 0.051 12.7 5.0 0.06 12.4 2.0 1.7 1 1 1 2 2 2 0 Myc amino-terminal region NOA36 PF06524.7 EFI27060.1 - 0.097 11.9 10.1 0.2 10.8 7.0 1.5 1 1 0 1 1 1 0 NOA36 protein Transpos_assoc PF13963.1 EFI27060.1 - 0.2 11.6 3.7 0.96 9.4 0.3 2.6 1 1 1 2 2 2 0 Transposase-associated domain Vfa1 PF08432.5 EFI27060.1 - 0.56 10.2 5.1 0.86 9.6 3.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 S-antigen PF05756.6 EFI27060.1 - 2.6 8.0 5.5 0.36 10.8 1.0 1.7 2 0 0 2 2 2 0 S-antigen protein Upf2 PF04050.9 EFI27060.1 - 3.7 7.3 16.0 5.6 6.7 11.1 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DNA_pol_phi PF04931.8 EFI27060.1 - 4.5 4.9 12.2 6 4.5 8.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.1 EFI27060.1 - 6.7 7.0 15.7 0.33 11.2 4.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.3 EFI27060.1 - 7 7.3 20.2 18 6.0 14.0 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal LIM PF00412.17 EFI27061.1 - 8.2e-31 105.8 28.5 9.6e-15 54.4 2.4 4.4 4 0 0 4 4 4 3 LIM domain CLTH PF10607.4 EFI27062.1 - 7e-35 119.8 0.1 1.5e-34 118.8 0.1 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain MscS_porin PF12795.2 EFI27062.1 - 0.016 14.4 0.2 0.03 13.6 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain zf-RING_UBOX PF13445.1 EFI27062.1 - 0.026 14.2 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Orthopox_A5L PF06193.6 EFI27062.1 - 0.027 14.4 0.7 0.063 13.2 0.5 1.6 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like CENP-F_leu_zip PF10473.4 EFI27062.1 - 0.029 14.2 0.6 0.077 12.8 0.4 1.7 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CK2S PF15011.1 EFI27062.1 - 0.038 13.7 0.3 0.093 12.5 0.2 1.6 1 0 0 1 1 1 0 Casein Kinase 2 substrate ACCA PF03255.9 EFI27062.1 - 0.054 13.0 2.3 0.59 9.6 0.1 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pkinase PF00069.20 EFI27063.1 - 4.7e-52 176.7 0.0 5.6e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27063.1 - 1.8e-25 89.5 0.0 2.2e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI27063.1 - 1.6e-05 24.0 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EFI27063.1 - 0.0019 17.2 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HlyIII PF03006.15 EFI27064.1 - 1.1e-61 208.1 20.5 1.3e-61 207.8 14.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Lig_chan PF00060.21 EFI27064.1 - 0.025 14.2 0.9 0.061 13.0 0.6 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel DUF2628 PF10947.3 EFI27064.1 - 2.1 8.1 8.0 0.49 10.2 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2628) UNC-93 PF05978.11 EFI27064.1 - 6.1 6.3 10.2 0.18 11.2 1.2 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 gpW PF02831.10 EFI27066.1 - 0.071 12.6 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 gpW DUF4149 PF13664.1 EFI27067.1 - 4.1 7.5 11.6 10 6.2 4.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) PX PF00787.19 EFI27068.1 - 9e-20 70.5 0.1 2.5e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.4 EFI27068.1 - 2.1e-13 50.0 0.4 5.1e-13 48.8 0.3 1.6 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 EFI27068.1 - 6.5e-07 28.6 0.0 1.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EFI27068.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Glyco_hydro_12 PF01670.11 EFI27071.1 - 7.9e-17 61.4 1.6 7.9e-17 61.4 1.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 Ripply PF14998.1 EFI27073.1 - 0.074 13.1 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription Regulator Transp_cyt_pur PF02133.10 EFI27075.1 - 6.9e-25 87.4 38.2 1.9e-23 82.7 26.5 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin M20_dimer PF07687.9 EFI27076.1 - 0.016 14.9 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase dimerisation domain E1-E2_ATPase PF00122.15 EFI27078.1 - 4.4e-57 192.7 0.3 4.4e-57 192.7 0.2 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EFI27078.1 - 2.3e-22 80.4 0.0 6.5e-22 79.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EFI27078.1 - 1.4e-13 50.1 0.0 3.6e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EFI27078.1 - 1.8e-13 51.1 0.1 4.8e-13 49.7 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EFI27078.1 - 0.00028 20.5 0.0 0.0018 17.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_61 PF03443.9 EFI27081.1 - 4.5e-05 23.3 0.0 5.2e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 BCDHK_Adom3 PF10436.4 EFI27083.1 - 2.7e-61 205.8 0.1 2e-40 137.9 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EFI27083.1 - 1.5e-17 63.3 0.0 3.6e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EFI27083.1 - 0.0012 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ig_3 PF13927.1 EFI27084.1 - 0.079 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin domain PSP PF04046.11 EFI27086.1 - 0.26 10.6 6.8 0.36 10.2 0.1 2.8 2 1 1 3 3 3 0 PSP Agglutinin PF07468.6 EFI27088.1 - 0.0022 17.9 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 Agglutinin DUF1996 PF09362.5 EFI27094.1 - 0.0008 19.1 0.1 0.0011 18.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.5 EFI27095.1 - 1.2e-40 139.6 0.2 1.6e-40 139.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HNH_2 PF13391.1 EFI27097.1 - 0.017 14.8 0.1 0.04 13.6 0.0 1.8 2 1 0 2 2 2 0 HNH endonuclease ADH_zinc_N PF00107.21 EFI27105.1 - 2.1e-23 82.3 0.0 3.3e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EFI27105.1 - 9.6e-06 26.5 0.1 1.7e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2132 PF09905.4 EFI27106.1 - 0.037 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) DUF4131 PF13567.1 EFI27106.1 - 0.086 12.2 0.8 0.13 11.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3583 PF12126.3 EFI27108.1 - 0.011 14.8 0.1 0.012 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Fungal_trans PF04082.13 EFI27111.1 - 6.4e-23 80.9 1.3 1.1e-22 80.1 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EFI27111.1 - 9.3e-08 31.8 8.9 9.3e-08 31.8 6.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 EFI27111.1 - 4.2e-06 26.7 2.6 4.2e-06 26.7 1.8 3.8 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EFI27111.1 - 0.00043 20.4 23.7 0.00055 20.0 2.4 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EFI27111.1 - 0.0049 17.1 22.1 0.036 14.4 1.9 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.2 EFI27111.1 - 0.019 15.1 5.1 0.043 14.0 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EFI27111.1 - 0.64 10.0 10.0 0.036 13.9 1.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EFI27111.1 - 2.5 8.3 8.0 3.9 7.7 0.5 2.9 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding F-box PF00646.28 EFI27112.1 - 1e-06 28.2 3.7 2.8e-06 26.8 2.4 2.0 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 EFI27112.1 - 1.2e-06 28.0 2.7 2.8e-06 26.9 1.9 1.7 1 0 0 1 1 1 1 F-box-like Slx4 PF09494.5 EFI27112.1 - 0.036 13.8 0.1 0.083 12.6 0.1 1.6 1 0 0 1 1 1 0 Slx4 endonuclease Cauli_DNA-bind PF03310.8 EFI27113.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DUF4246 PF14033.1 EFI27114.1 - 9.2e-146 486.3 0.2 5.8e-122 407.8 0.0 3.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EFI27114.1 - 0.017 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EFI27114.1 - 0.11 12.9 0.1 0.38 11.2 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily F-box PF00646.28 EFI27115.1 - 3e-08 33.0 4.1 4e-08 32.7 2.6 1.4 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 EFI27115.1 - 1.1e-06 28.1 2.3 1.6e-06 27.6 1.6 1.3 1 0 0 1 1 1 1 F-box-like Slx4 PF09494.5 EFI27116.1 - 0.0024 17.5 0.5 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Slx4 endonuclease Mit_KHE1 PF10173.4 EFI27117.1 - 1.7e-50 171.4 0.0 2.4e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Peptidase_M43 PF05572.8 EFI27118.1 - 4.2e-20 71.8 0.0 8.7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EFI27118.1 - 1.1e-05 25.4 0.1 2.7e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EFI27118.1 - 4.1e-05 23.6 0.1 7.4e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EFI27118.1 - 0.0019 17.7 0.1 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EFI27118.1 - 0.0048 17.4 2.2 0.018 15.5 1.5 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 EFI27118.1 - 0.026 14.2 0.1 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.19 EFI27118.1 - 0.033 13.9 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Matrixin PPP4R2 PF09184.6 EFI27118.1 - 0.042 13.3 4.8 0.068 12.7 3.3 1.2 1 0 0 1 1 1 0 PPP4R2 MSP1_C PF07462.6 EFI27118.1 - 0.12 10.7 2.8 0.18 10.1 1.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Daxx PF03344.10 EFI27118.1 - 0.78 8.1 5.6 1.1 7.6 3.9 1.1 1 0 0 1 1 1 0 Daxx Family TPR_12 PF13424.1 EFI27119.1 - 6.4e-34 115.7 6.3 0.0092 15.8 0.0 13.9 6 2 8 14 14 14 10 Tetratricopeptide repeat CHAT PF12770.2 EFI27119.1 - 6.5e-27 94.3 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_17 PF13431.1 EFI27119.1 - 8.1e-17 59.9 3.1 2.3 8.6 0.0 12.4 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_11 PF13414.1 EFI27119.1 - 4.1e-13 48.7 15.3 0.25 11.0 0.1 10.5 4 3 7 11 11 11 4 TPR repeat TPR_10 PF13374.1 EFI27119.1 - 6.9e-11 41.7 38.5 0.0065 16.3 0.0 12.9 15 2 1 16 16 16 4 Tetratricopeptide repeat TPR_2 PF07719.12 EFI27119.1 - 0.00029 20.5 1.1 3.8 7.6 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat Peptidase_C25 PF01364.13 EFI27119.1 - 0.042 12.8 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 TPR_1 PF00515.23 EFI27119.1 - 0.067 12.8 10.7 2.2 8.0 0.0 8.3 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.1 EFI27119.1 - 1.9 9.3 13.1 11 6.9 0.0 8.2 10 3 2 12 12 12 0 Tetratricopeptide repeat Flavoprotein PF02441.14 EFI27120.1 - 1.6e-40 137.7 0.1 2e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein DUF4246 PF14033.1 EFI27122.1 - 3.7e-172 573.4 0.4 3.3e-164 547.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EFI27122.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase ATP-grasp_3 PF02655.9 EFI27122.1 - 0.18 11.6 0.0 3.8 7.3 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain F-box-like PF12937.2 EFI27124.1 - 7.2e-06 25.6 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EFI27124.1 - 0.04 13.5 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 F-box domain PGAP1 PF07819.8 EFI27126.1 - 0.00019 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EFI27126.1 - 0.0012 18.8 0.6 0.007 16.2 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EFI27126.1 - 0.0053 15.7 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EFI27126.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EFI27126.1 - 0.037 13.3 0.0 0.084 12.1 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Vezatin PF12632.2 EFI27127.1 - 0.066 12.2 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Steroid_dh PF02544.11 EFI27128.1 - 3e-29 101.7 5.3 3.2e-10 39.9 0.3 3.5 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EFI27128.1 - 2.1e-07 30.5 0.0 3.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TPR_12 PF13424.1 EFI27129.1 - 4.8e-43 144.9 8.4 6.9e-06 25.9 0.1 14.2 2 2 10 14 14 14 12 Tetratricopeptide repeat TPR_11 PF13414.1 EFI27129.1 - 9.5e-25 86.0 10.2 0.025 14.2 0.5 12.1 4 2 9 15 15 15 10 TPR repeat CHAT PF12770.2 EFI27129.1 - 4.3e-23 81.8 0.0 1.2e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 CHAT domain TPR_10 PF13374.1 EFI27129.1 - 8.9e-22 76.3 21.8 0.26 11.2 0.0 14.4 16 0 0 16 16 16 7 Tetratricopeptide repeat TPR_17 PF13431.1 EFI27129.1 - 1.3e-12 46.7 1.0 0.73 10.1 0.0 11.0 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_16 PF13432.1 EFI27129.1 - 3.6e-08 33.8 16.2 2.4 8.9 0.1 9.6 8 3 4 12 12 12 1 Tetratricopeptide repeat TPR_2 PF07719.12 EFI27129.1 - 1.2e-07 31.0 16.5 7.9 6.6 0.2 12.3 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_8 PF13181.1 EFI27129.1 - 6.3e-06 25.6 0.6 0.31 10.9 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EFI27129.1 - 2.3e-05 23.7 19.5 1.5 8.5 0.1 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat Reo_sigmaC PF04582.7 EFI27129.1 - 0.002 17.3 2.7 3.5 6.7 0.0 3.6 3 0 0 3 3 3 2 Reovirus sigma C capsid protein 7tm_6 PF02949.15 EFI27129.1 - 0.015 14.2 1.5 18 4.0 0.0 4.9 5 1 0 5 5 5 0 7tm Odorant receptor MHC2-interact PF09307.5 EFI27129.1 - 0.031 14.0 0.0 5.6 6.7 0.0 3.9 4 0 0 4 4 4 0 CLIP, MHC2 interacting p450 PF00067.17 EFI27130.1 - 3.1e-46 157.8 0.0 1.4e-45 155.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EFI27131.1 - 2e-54 184.8 0.0 1.4e-28 99.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ABC2_membrane PF01061.19 EFI27137.1 - 0.055 12.6 0.6 0.071 12.2 0.4 1.1 1 0 0 1 1 1 0 ABC-2 type transporter PetL PF05115.9 EFI27138.1 - 0.13 12.2 1.5 0.35 10.8 1.0 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Ebp2 PF05890.7 EFI27140.1 - 1.3e-73 247.6 17.8 1.3e-73 247.6 12.3 2.5 3 0 0 3 3 3 1 Eukaryotic rRNA processing protein EBP2 HrpA_pilin PF09589.5 EFI27140.1 - 0.00096 19.5 0.0 0.062 13.7 0.0 3.0 2 2 0 2 2 2 1 HrpA pilus formation protein GMC_oxred_N PF00732.14 EFI27141.1 - 1.1e-67 228.3 0.0 1.5e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EFI27141.1 - 8.2e-32 110.4 0.0 1.6e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EFI27141.1 - 5.6e-06 26.2 0.0 0.00052 19.9 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EFI27141.1 - 2.1e-05 23.6 0.0 3.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EFI27141.1 - 0.00024 20.1 0.0 0.00043 19.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EFI27141.1 - 0.0029 16.5 0.0 0.0053 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EFI27141.1 - 0.0086 15.1 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EFI27141.1 - 0.028 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EFI27141.1 - 0.16 10.3 0.0 0.27 9.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein BTB PF00651.26 EFI27142.1 - 0.00019 21.4 0.1 0.0007 19.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Transposase_21 PF02992.9 EFI27144.1 - 2.2e-35 121.8 0.0 4.8e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EFI27144.1 - 0.024 14.0 0.0 0.11 11.9 0.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4218) PDZ_2 PF13180.1 EFI27144.1 - 0.093 12.6 0.0 8.4 6.3 0.0 2.6 2 0 0 2 2 2 0 PDZ domain PcfK PF14058.1 EFI27144.1 - 0.24 11.5 0.1 0.52 10.4 0.1 1.4 1 0 0 1 1 1 0 PcfK-like protein Upf2 PF04050.9 EFI27144.1 - 1.5 8.5 6.4 2.6 7.8 4.4 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 YniB PF14002.1 EFI27148.1 - 0.0014 18.1 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 2 YniB-like protein HHA PF05321.6 EFI27148.1 - 0.5 10.5 3.3 5.7 7.1 0.2 2.7 3 0 0 3 3 3 0 Haemolysin expression modulating protein DUF1049 PF06305.6 EFI27150.1 - 0.0074 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) MASE1 PF05231.9 EFI27150.1 - 0.018 14.0 0.1 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 MASE1 Imm10 PF15562.1 EFI27150.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 10 SKG6 PF08693.5 EFI27150.1 - 0.11 11.8 0.5 0.19 11.0 0.4 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF883 PF05957.8 EFI27150.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) P12 PF12669.2 EFI27150.1 - 0.18 12.0 0.5 0.33 11.1 0.3 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family PGAP1 PF07819.8 EFI27151.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EFI27151.1 - 0.0014 18.5 0.4 0.0047 16.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EFI27151.1 - 0.0046 16.7 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EFI27151.1 - 0.079 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3605 PF12239.3 EFI27152.1 - 3.8e-29 101.5 2.5 6.1e-21 74.9 0.7 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3605) DUF2540 PF10802.3 EFI27152.1 - 0.00022 20.8 0.0 0.039 13.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2540) HIT PF01230.18 EFI27152.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 HIT domain adh_short PF00106.20 EFI27153.1 - 2e-24 86.3 2.6 1.6e-23 83.4 1.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EFI27153.1 - 1.5e-13 51.0 0.0 2.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EFI27153.1 - 2e-08 34.1 1.7 5.7e-07 29.3 1.2 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EFI27153.1 - 1.4e-06 28.4 0.1 2.1e-06 27.8 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EFI27153.1 - 6.1e-06 25.8 0.3 1.2e-05 24.9 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EFI27153.1 - 0.008 15.1 0.6 0.036 12.9 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EFI27153.1 - 0.029 13.0 0.1 0.052 12.2 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EFI27153.1 - 0.045 13.7 0.2 1.3 8.9 0.0 2.6 1 1 2 3 3 3 0 TrkA-N domain NmrA PF05368.8 EFI27153.1 - 0.064 12.4 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family MutS_V PF00488.16 EFI27156.1 - 5.1e-57 192.9 0.1 6.7e-57 192.5 0.0 1.1 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EFI27156.1 - 4.9e-06 26.4 1.1 1.2e-05 25.2 0.3 1.9 2 1 0 2 2 2 1 MutS domain III AAA_22 PF13401.1 EFI27156.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MutS_III PF05192.13 EFI27157.1 - 8.4e-28 97.5 0.1 1.2e-27 97.0 0.1 1.2 1 0 0 1 1 1 1 MutS domain III FG-GAP PF01839.18 EFI27157.1 - 0.057 13.1 0.4 0.13 11.9 0.3 1.6 1 0 0 1 1 1 0 FG-GAP repeat SET PF00856.23 EFI27159.1 - 6.9e-15 55.7 0.0 4.4e-14 53.1 0.0 2.2 1 1 0 1 1 1 1 SET domain SHOCT PF09851.4 EFI27160.1 - 0.055 12.9 2.0 5 6.7 0.0 2.6 2 0 0 2 2 2 0 Short C-terminal domain zf-C3H1 PF10650.4 EFI27161.1 - 0.03 13.8 0.4 0.03 13.8 0.3 2.2 2 0 0 2 2 2 0 Putative zinc-finger domain RICTOR_N PF14664.1 EFI27163.1 - 7.9e-90 301.1 3.2 7.9e-90 301.1 2.2 2.2 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EFI27163.1 - 3.3e-83 278.1 4.3 8e-82 273.6 0.6 3.9 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EFI27163.1 - 6.4e-33 113.1 0.1 1.2e-31 109.0 0.0 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ribosomal_L22 PF00237.14 EFI27163.1 - 3.5e-29 100.8 0.1 1.4e-28 98.8 0.1 2.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e RICTOR_V PF14668.1 EFI27163.1 - 1.1e-28 98.9 0.1 1.9e-26 91.7 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EFI27163.1 - 4.3e-06 26.9 0.6 0.12 12.6 0.0 5.4 5 1 1 6 6 6 2 HEAT repeats HR1 PF02185.11 EFI27163.1 - 0.0075 15.9 8.6 0.031 14.0 5.9 2.2 1 0 0 1 1 1 1 Hr1 repeat HEAT_EZ PF13513.1 EFI27163.1 - 0.037 14.5 0.9 1.5 9.4 0.0 4.0 5 0 0 5 5 5 0 HEAT-like repeat GRIN_C PF15235.1 EFI27163.1 - 0.066 13.2 2.3 0.11 12.5 0.7 2.2 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus DASH_Dad1 PF08649.5 EFI27168.1 - 2.6e-15 55.8 0.2 3.3e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.5 EFI27168.1 - 0.031 14.1 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pap_E4 PF02711.9 EFI27169.1 - 0.25 12.2 2.3 0.29 11.9 1.6 1.1 1 0 0 1 1 1 0 E4 protein Methyltransf_33 PF10017.4 EFI27170.1 - 1.5e-11 44.3 0.2 2.3e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Aminotran_1_2 PF00155.16 EFI27171.1 - 2e-19 69.7 0.0 2.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II F-box PF00646.28 EFI27174.1 - 0.0064 16.1 0.1 0.014 14.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EFI27174.1 - 0.0088 15.7 0.6 0.019 14.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EFI27174.1 - 0.047 13.4 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain Peptidase_M20 PF01546.23 EFI27177.1 - 3.1e-27 95.3 0.0 5.5e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EFI27177.1 - 5.6e-24 83.0 8.2 2e-08 33.8 0.1 8.1 8 0 0 8 8 8 4 WD domain, G-beta repeat M20_dimer PF07687.9 EFI27177.1 - 2.5e-13 49.7 0.0 4.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 EFI27177.1 - 0.0009 17.4 0.3 0.16 10.0 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EFI27177.1 - 0.074 13.3 0.0 0.66 10.3 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Peptidase_M28 PF04389.12 EFI27177.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Mon1 PF03164.9 EFI27178.1 - 9.5e-50 169.4 0.0 3.5e-17 62.1 0.0 3.0 2 1 1 3 3 3 3 Trafficking protein Mon1 IGR PF09597.5 EFI27178.1 - 1.9e-14 53.3 0.0 3.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif F-box-like PF12937.2 EFI27179.1 - 0.076 12.7 0.1 0.076 12.7 0.1 3.5 4 0 0 4 4 4 0 F-box-like F-box PF00646.28 EFI27179.1 - 0.25 11.0 4.0 0.84 9.3 0.1 3.4 3 1 0 3 3 3 0 F-box domain Scm3 PF10384.4 EFI27180.1 - 1.6e-14 53.0 0.6 3.3e-14 52.0 0.4 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 HSP20 PF00011.16 EFI27181.1 - 4.6e-15 55.3 0.2 4.5e-13 48.9 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 EFI27181.1 - 0.071 12.7 0.1 1.7 8.2 0.0 2.1 1 1 1 2 2 2 0 GvpH CS PF04969.11 EFI27181.1 - 0.12 12.8 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 CS domain DUF1325 PF07039.6 EFI27182.1 - 9.4e-31 106.1 0.0 1.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain RasGEF PF00617.14 EFI27185.1 - 4.6e-58 196.0 0.2 8.1e-58 195.2 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EFI27185.1 - 9.6e-20 70.6 0.0 2.9e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif HIT PF01230.18 EFI27185.1 - 1.8e-19 70.0 0.1 4.1e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 HIT domain SH3_1 PF00018.23 EFI27185.1 - 2e-12 46.2 0.2 4.7e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 SH3 domain DcpS_C PF11969.3 EFI27185.1 - 3.3e-12 46.6 0.0 8.3e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SH3_2 PF07653.12 EFI27185.1 - 1.7e-11 43.4 0.0 3.4e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EFI27185.1 - 1.5e-10 40.5 0.2 2.9e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain CwfJ_C_1 PF04677.10 EFI27185.1 - 1.2e-08 34.6 0.0 2.8e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SH3_3 PF08239.6 EFI27185.1 - 0.11 12.7 0.5 0.24 11.5 0.4 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain She9_MDM33 PF05546.6 EFI27186.1 - 5.6e-71 238.3 11.6 6.5e-71 238.1 7.6 1.4 1 1 0 1 1 1 1 She9 / Mdm33 family Phage_glycop_gL PF11108.3 EFI27186.1 - 0.022 14.6 0.0 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 Viral glycoprotein L MbeB_N PF04837.7 EFI27186.1 - 0.44 10.6 4.7 12 6.0 0.2 4.0 3 0 0 3 3 3 0 MbeB-like, N-term conserved region FAD_binding_1 PF00667.15 EFI27187.1 - 5.8e-53 179.5 0.0 3.8e-52 176.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EFI27187.1 - 9.7e-31 106.6 2.0 9.8e-31 106.6 0.3 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EFI27187.1 - 1.2e-20 74.0 0.0 5.1e-20 72.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EFI27187.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain DDE_Tnp_1_4 PF13701.1 EFI27187.1 - 0.2 9.8 0.0 0.27 9.3 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 HVSL PF09749.4 EFI27189.1 - 1.9e-45 154.7 0.1 3.7e-45 153.8 0.1 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 EFI27189.1 - 2.5e-06 27.3 3.0 2.9e-06 27.0 0.8 1.8 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily DUF4080 PF13311.1 EFI27189.1 - 0.044 13.8 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) CMV_US PF08001.6 EFI27189.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 CMV US DUF3446 PF11928.3 EFI27190.1 - 0.033 14.3 1.3 0.033 14.3 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Kelch_6 PF13964.1 EFI27190.1 - 0.072 13.2 0.3 7 7.0 0.0 2.7 2 0 0 2 2 2 0 Kelch motif DUF563 PF04577.9 EFI27191.1 - 3.2e-22 79.4 0.1 6e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TEX13 PF15186.1 EFI27192.1 - 0.11 12.0 0.6 0.15 11.6 0.4 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Hpt PF01627.18 EFI27193.1 - 4e-12 45.9 0.8 5.6e-12 45.4 0.5 1.2 1 0 0 1 1 1 1 Hpt domain Muted PF14942.1 EFI27193.1 - 0.083 12.7 0.7 0.14 12.0 0.5 1.3 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein CoA_transf_3 PF02515.12 EFI27194.1 - 8.9e-66 220.7 0.0 2.5e-65 219.3 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III DUF4436 PF14494.1 EFI27197.1 - 1.9e-10 40.5 0.1 7.4e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4436) OppC_N PF12911.2 EFI27197.1 - 1.9 7.9 5.2 9.6 5.6 2.2 2.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C zf-MYND PF01753.13 EFI27198.1 - 1.1e-08 34.8 14.6 2.2e-08 33.8 10.1 1.5 1 0 0 1 1 1 1 MYND finger SET PF00856.23 EFI27198.1 - 1.6e-08 34.9 0.3 7.7e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 SET domain DUF3561 PF12084.3 EFI27200.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) SQS_PSY PF00494.14 EFI27201.1 - 2.9e-52 177.6 0.0 3.6e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Mit_ribos_Mrp51 PF11709.3 EFI27201.1 - 0.12 11.5 0.3 0.21 10.7 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Sugar_tr PF00083.19 EFI27205.1 - 3.1e-49 167.7 11.1 1.4e-25 89.8 0.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EFI27205.1 - 3e-12 45.9 16.2 1.7e-07 30.2 2.5 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.7 EFI27205.1 - 0.17 11.7 1.3 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) COPIIcoated_ERV PF07970.7 EFI27208.1 - 1.7e-66 224.0 0.0 2.3e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EFI27208.1 - 7.1e-31 106.0 0.3 7.1e-31 106.0 0.2 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sec1 PF00995.18 EFI27209.1 - 7.7e-140 467.1 0.0 8.8e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family adh_short PF00106.20 EFI27211.1 - 1.1e-10 41.7 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EFI27211.1 - 3e-07 30.2 0.0 4.1e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EFI27211.1 - 0.0027 17.7 0.1 0.0042 17.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EFI27211.1 - 0.0043 17.1 0.0 0.0059 16.7 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EFI27211.1 - 0.038 13.4 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EFI27211.1 - 0.17 10.7 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3530 PF12048.3 EFI27213.1 - 0.02 13.8 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF810 PF05664.6 EFI27213.1 - 0.05 11.8 0.0 0.067 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF810) SLAC1 PF03595.12 EFI27215.1 - 4.8e-33 114.1 39.1 6.5e-33 113.7 27.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Shisa PF13908.1 EFI27215.1 - 0.0065 16.6 0.1 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RPAP1_C PF08620.5 EFI27216.1 - 6.2e-19 67.6 0.0 1.3e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EFI27216.1 - 4.5e-09 35.7 2.2 1.1e-08 34.5 1.6 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal Peptidase_M16 PF00675.15 EFI27217.1 - 1.2e-54 184.0 1.0 4.4e-54 182.2 0.4 2.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EFI27217.1 - 4.7e-45 153.5 0.0 1.9e-42 145.0 0.0 3.1 3 0 0 3 3 3 1 Peptidase M16 inactive domain adh_short PF00106.20 EFI27217.1 - 9.6e-22 77.6 0.3 7.3e-21 74.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EFI27217.1 - 6.8e-09 35.6 0.2 5.6e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EFI27217.1 - 1.3e-05 24.7 0.0 2.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EFI27217.1 - 1.9e-05 24.5 0.1 5.1e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EFI27217.1 - 0.00068 19.6 0.2 0.0021 18.0 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EFI27217.1 - 0.11 11.3 0.0 0.24 10.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PRP1_N PF06424.7 EFI27219.1 - 0.035 14.4 0.3 0.043 14.1 0.2 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF4139 PF13598.1 EFI27220.1 - 2.3e-82 276.8 4.9 1.3e-54 185.6 0.1 3.2 1 1 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EFI27220.1 - 8.5e-22 77.5 1.9 1.7e-21 76.6 0.0 2.5 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) DUF4064 PF13273.1 EFI27222.1 - 0.35 10.9 0.1 0.35 10.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Mito_carr PF00153.22 EFI27223.1 - 2.9e-70 232.0 2.4 2.8e-24 84.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 EFI27224.1 - 0.00073 19.4 18.2 0.0013 18.5 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EFI27225.1 - 6.7e-15 54.6 0.0 1.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain C1_1 PF00130.17 EFI27226.1 - 1.5e-12 47.0 5.9 2.6e-12 46.2 4.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.18 EFI27226.1 - 1.5e-11 44.2 0.1 6.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EFI27226.1 - 5.7e-10 38.6 0.0 1.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EFI27226.1 - 2.5e-09 36.3 0.0 4.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EFI27226.1 - 3.7e-05 23.1 0.0 9.9e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain DUF663 PF04950.7 EFI27230.1 - 2e-90 302.7 0.0 2e-90 302.7 0.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EFI27230.1 - 6.8e-30 102.4 0.0 3.6e-29 100.1 0.0 2.2 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EFI27230.1 - 5.2e-06 26.0 3.6 0.00025 20.5 0.0 2.7 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EFI27230.1 - 1.2e-05 25.5 0.0 3.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EFI27230.1 - 2.5e-05 25.0 0.0 2.5e-05 25.0 0.0 4.2 4 2 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EFI27230.1 - 5e-05 23.3 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Rtf2 PF04641.7 EFI27230.1 - 0.00016 20.9 5.4 0.00016 20.9 3.7 3.8 4 0 0 4 4 3 1 Rtf2 RING-finger MobB PF03205.9 EFI27230.1 - 0.00042 20.0 0.4 0.0012 18.5 0.3 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EFI27230.1 - 0.00053 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EFI27230.1 - 0.00084 18.8 0.1 0.0023 17.4 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EFI27230.1 - 0.001 19.4 0.0 0.001 19.4 0.0 2.4 2 0 0 2 2 1 1 ABC transporter NACHT PF05729.7 EFI27230.1 - 0.001 18.7 0.1 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 EFI27230.1 - 0.0012 18.7 0.1 0.0064 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EFI27230.1 - 0.0012 18.7 0.2 0.004 17.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 EFI27230.1 - 0.0018 17.8 0.1 0.0053 16.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EFI27230.1 - 0.0021 18.5 0.0 0.0059 17.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_19 PF13245.1 EFI27230.1 - 0.0028 17.3 0.2 0.007 16.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EFI27230.1 - 0.0029 17.8 0.1 0.0029 17.8 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_14 PF13173.1 EFI27230.1 - 0.005 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EFI27230.1 - 0.0051 16.2 0.0 0.016 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EFI27230.1 - 0.0063 16.6 0.0 0.018 15.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EFI27230.1 - 0.0075 16.2 0.1 0.0075 16.2 0.1 2.2 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 EFI27230.1 - 0.0088 15.5 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain NTPase_1 PF03266.10 EFI27230.1 - 0.011 15.4 0.5 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.17 EFI27230.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.14 EFI27230.1 - 0.016 14.6 0.2 0.033 13.6 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EFI27230.1 - 0.018 14.7 0.1 0.05 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EFI27230.1 - 0.038 13.1 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 EFI27230.1 - 0.49 9.9 9.5 2.1 7.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 EFI27231.1 - 6.6e-40 137.1 0.1 2.9e-39 135.0 0.1 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EFI27231.1 - 2e-12 47.1 0.0 1.7e-10 40.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EFI27231.1 - 6.9e-07 28.9 0.1 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EFI27231.1 - 0.0057 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EFI27231.1 - 0.0077 16.3 0.1 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EFI27231.1 - 0.058 13.3 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EFI27231.1 - 0.064 13.5 0.2 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA PF00004.24 EFI27231.1 - 0.088 13.0 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EFI27231.1 - 0.098 12.6 2.2 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EFI27231.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 NTPase SMC_N PF02463.14 EFI27235.1 - 2.9e-68 229.3 1.3 3.8e-68 229.0 0.9 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EFI27235.1 - 6.6e-29 100.3 0.0 2.8e-28 98.2 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EFI27235.1 - 8.1e-13 48.9 7.9 2.3e-06 27.7 0.0 3.6 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EFI27235.1 - 1.3e-12 48.4 26.7 1.3e-12 48.4 18.5 5.9 2 2 1 3 3 2 1 AAA domain Reo_sigmaC PF04582.7 EFI27235.1 - 6.1e-05 22.3 14.4 0.23 10.6 1.7 5.2 3 1 0 5 5 5 2 Reovirus sigma C capsid protein AAA_29 PF13555.1 EFI27235.1 - 0.00068 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EFI27235.1 - 0.0011 16.4 13.3 0.0011 16.4 9.2 4.4 2 2 0 3 3 3 1 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EFI27235.1 - 0.054 11.9 71.1 0.081 11.3 4.5 6.2 3 2 1 5 5 5 0 AAA domain ABC_tran PF00005.22 EFI27235.1 - 0.14 12.4 23.3 0.83 9.9 0.4 5.3 3 2 0 3 3 3 0 ABC transporter Baculo_PEP_C PF04513.7 EFI27235.1 - 1.2 8.9 15.0 2.6 7.8 1.0 5.7 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EFI27235.1 - 5.6 6.8 27.0 0.026 14.3 1.6 6.3 6 1 0 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF346 PF03984.8 EFI27237.1 - 0.12 11.8 1.3 6.7 6.2 0.2 2.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) ubiquitin PF00240.18 EFI27242.1 - 1.4e-18 65.9 0.6 2.4e-18 65.2 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EFI27242.1 - 2e-10 40.1 0.7 3.2e-10 39.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EFI27242.1 - 7.2e-10 38.4 0.0 7.2e-10 38.4 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 EFI27242.1 - 3.8e-06 26.9 0.0 6.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EFI27242.1 - 0.11 12.4 0.1 0.27 11.1 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Serglycin PF04360.7 EFI27242.1 - 0.16 11.7 0.1 0.16 11.7 0.1 3.5 4 0 0 4 4 4 0 Serglycin zf-H2C2_5 PF13909.1 EFI27243.1 - 4.4e-06 26.5 29.2 0.1 12.8 1.2 6.7 7 0 0 7 7 7 4 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EFI27243.1 - 0.0019 18.4 35.4 0.26 11.6 0.2 6.6 7 0 0 7 7 7 4 C2H2-type zinc finger IBR PF01485.16 EFI27243.1 - 0.019 14.8 9.7 8.9 6.2 0.3 4.9 1 1 4 5 5 5 0 IBR domain DUF1069 PF06370.6 EFI27243.1 - 0.14 11.5 1.4 6.7 6.0 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1069) AMA-1 PF02430.10 EFI27243.1 - 0.14 10.9 1.1 0.16 10.7 0.7 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 DUF3505 PF12013.3 EFI27243.1 - 0.15 12.2 16.0 12 6.2 0.0 4.9 2 2 4 6 6 6 0 Protein of unknown function (DUF3505) DUF2719 PF10891.3 EFI27243.1 - 0.95 9.1 4.7 4.5 7.0 0.4 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2719) zf-C2H2 PF00096.21 EFI27243.1 - 2.7 8.4 28.5 2.6 8.5 2.0 5.6 6 0 0 6 6 6 0 Zinc finger, C2H2 type Zip PF02535.17 EFI27244.1 - 0.23 10.4 3.4 0.34 9.8 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.3 EFI27244.1 - 0.46 9.9 4.6 1.9 7.9 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) zf-C2H2_4 PF13894.1 EFI27246.1 - 1.5e-06 28.0 19.8 0.47 10.9 0.3 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EFI27246.1 - 1.6e-05 24.9 33.0 0.29 11.5 0.2 5.5 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EFI27246.1 - 0.00029 20.8 21.6 0.79 10.0 0.3 5.3 5 0 0 5 5 5 4 C2H2-type zinc-finger domain DUF4442 PF14539.1 EFI27246.1 - 0.01 15.8 0.0 11 6.0 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4442) Pentapeptide_4 PF13599.1 EFI27246.1 - 0.095 12.5 0.4 18 5.2 0.3 3.7 1 1 0 1 1 1 0 Pentapeptide repeats (9 copies) Toxin_65 PF15543.1 EFI27246.1 - 0.11 12.1 0.0 9.4 5.8 0.0 3.1 1 1 3 4 4 4 0 Putative toxin 65 THAP PF05485.7 EFI27246.1 - 0.17 12.0 9.5 41 4.4 0.1 4.5 2 1 3 5 5 5 0 THAP domain zf-C4_Topoisom PF01396.14 EFI27246.1 - 6.8 6.2 14.5 35 4.0 0.1 4.9 5 0 0 5 5 5 0 Topoisomerase DNA binding C4 zinc finger DUF202 PF02656.10 EFI27248.1 - 3e-16 59.3 4.4 3e-16 59.3 3.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MFS_1 PF07690.11 EFI27249.1 - 3.5e-49 167.4 47.1 7.2e-44 149.9 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EFI27249.1 - 0.005 14.9 4.7 0.037 12.1 3.0 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Ion_trans_2 PF07885.11 EFI27251.1 - 5.2e-26 90.1 25.3 3.3e-16 58.7 6.0 3.2 3 0 0 3 3 3 2 Ion channel 7tm_6 PF02949.15 EFI27251.1 - 0.0029 16.5 0.0 0.0072 15.2 0.0 1.6 1 0 0 1 1 1 1 7tm Odorant receptor TMEM125 PF15109.1 EFI27251.1 - 0.11 12.5 1.4 0.35 11.0 0.2 2.3 2 0 0 2 2 2 0 TMEM125 protein family SpoIIAA-like PF11964.3 EFI27252.1 - 0.1 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 SpoIIAA-like PCYCGC PF13798.1 EFI27253.1 - 0.091 12.4 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif WD40 PF00400.27 EFI27256.1 - 1.5e-72 237.0 65.2 1.4e-11 43.7 0.3 15.0 12 2 3 15 15 15 14 WD domain, G-beta repeat NACHT PF05729.7 EFI27256.1 - 8.2e-09 35.3 0.1 2.2e-08 33.9 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EFI27256.1 - 0.0013 18.7 0.2 0.0071 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EFI27256.1 - 0.0025 17.9 0.0 0.55 10.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 EFI27256.1 - 0.027 14.6 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EFI27256.1 - 0.03 14.2 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EFI27256.1 - 0.035 14.9 0.1 0.13 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain TrbL PF04610.9 EFI27256.1 - 0.044 13.4 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Acetyltransf_1 PF00583.19 EFI27267.1 - 0.13 12.3 0.2 0.22 11.5 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Ras PF00071.17 EFI27268.1 - 4e-21 75.0 0.0 1.9e-20 72.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EFI27268.1 - 0.00038 20.9 0.0 0.006 17.0 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EFI27268.1 - 0.0031 16.7 0.1 0.029 13.5 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EFI27268.1 - 0.045 13.1 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.17 EFI27269.1 - 2.6e-20 72.4 0.0 2.9e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EFI27269.1 - 0.0007 20.0 0.0 0.00095 19.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein DUF3060 PF11259.3 EFI27270.1 - 0.18 11.4 0.8 0.31 10.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) DUF995 PF06191.7 EFI27272.1 - 0.0086 15.4 3.9 0.45 9.8 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF995) MVL PF12151.3 EFI27272.1 - 0.27 10.9 10.3 2.6 7.7 0.1 4.0 3 1 1 4 4 4 0 Mannan-binding protein Mst1_SARAH PF11629.3 EFI27273.1 - 0.094 12.5 0.6 7 6.5 0.1 2.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 OCC1 PF15506.1 EFI27275.1 - 0.088 12.7 0.1 0.099 12.5 0.1 1.1 1 0 0 1 1 1 0 OCC1 family PNPase PF03726.9 EFI27278.1 - 0.07 13.4 1.0 2.9 8.2 0.2 2.1 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PIF1 PF05970.9 EFI27280.1 - 2e-25 89.5 0.0 5.3e-25 88.1 0.0 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EFI27280.1 - 1.3e-09 37.8 0.0 1.6e-08 34.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EFI27280.1 - 0.0018 17.9 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 EFI27280.1 - 0.0025 16.5 0.0 0.0045 15.6 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain ArgK PF03308.11 EFI27280.1 - 0.043 12.5 0.0 0.094 11.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein DUF947 PF06102.7 EFI27282.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF947) PRANC PF09372.5 EFI27284.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 PRANC domain F-box-like PF12937.2 EFI27284.1 - 0.42 10.3 3.6 1.2 8.8 0.0 2.9 3 1 0 3 3 3 0 F-box-like Paxillin PF03535.8 EFI27286.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Paxillin family Tet_JBP PF12851.2 EFI27290.1 - 1.4e-18 66.7 0.0 2.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.2 EFI27291.1 - 6.7e-18 64.5 0.0 1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF4254 PF14063.1 EFI27292.1 - 0.0063 16.1 0.1 0.0084 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4254) IncA PF04156.9 EFI27292.1 - 0.032 13.8 1.1 0.046 13.3 0.8 1.2 1 0 0 1 1 1 0 IncA protein COG2 PF06148.6 EFI27292.1 - 0.034 14.0 0.9 0.05 13.4 0.7 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.1 EFI27292.1 - 0.036 13.9 4.9 0.049 13.5 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DDE_Tnp_IS66 PF03050.9 EFI27292.1 - 0.052 12.7 1.4 0.11 11.6 1.0 1.4 1 1 0 1 1 1 0 Transposase IS66 family AAA_13 PF13166.1 EFI27292.1 - 0.066 11.6 0.2 0.082 11.3 0.1 1.0 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.6 EFI27292.1 - 0.078 12.4 0.5 0.1 11.9 0.4 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 zf-C4H2 PF10146.4 EFI27292.1 - 0.078 12.9 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein IFT57 PF10498.4 EFI27292.1 - 0.094 11.4 1.8 0.13 10.9 1.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Atg14 PF10186.4 EFI27292.1 - 0.25 10.2 3.8 0.34 9.8 2.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 EFI27292.1 - 0.32 10.6 3.1 0.43 10.2 2.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 EFI27294.1 - 0.046 13.7 18.2 0.15 12.0 7.3 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EFI27294.1 - 0.76 9.3 30.3 0.25 10.9 6.4 2.9 1 1 2 3 3 3 0 IncA protein Mu-like_Pro PF10123.4 EFI27294.1 - 7.9 5.8 15.0 8.2 5.7 9.6 1.5 1 1 0 1 1 1 0 Mu-like prophage I protein Reo_sigmaC PF04582.7 EFI27295.1 - 0.45 9.6 27.0 0.88 8.6 0.6 3.9 1 1 1 4 4 4 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EFI27295.1 - 1.9 8.2 75.4 0.043 13.6 10.8 4.9 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EFI27295.1 - 4.2 6.9 94.8 0.016 14.7 9.8 5.5 1 1 1 3 3 3 0 IncA protein Filament PF00038.16 EFI27295.1 - 4.3 6.6 71.4 0.019 14.4 6.0 5.6 1 1 5 6 6 6 0 Intermediate filament protein Fer2_3 PF13085.1 EFI27297.1 - 0.059 13.2 0.5 0.065 13.0 0.4 1.2 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain VPS28 PF03997.7 EFI27300.1 - 8.4e-60 201.6 0.0 9.7e-60 201.4 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Ank_2 PF12796.2 EFI27301.1 - 3.2e-15 56.2 0.2 7.4e-07 29.4 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EFI27301.1 - 2.5e-13 50.1 0.6 0.17 12.4 0.0 6.4 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EFI27301.1 - 2.5e-10 40.2 2.4 0.007 16.5 0.1 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EFI27301.1 - 1.5e-09 37.2 0.1 9.6e-05 22.0 0.0 4.7 4 0 0 4 4 3 2 Ankyrin repeat Ank_3 PF13606.1 EFI27301.1 - 2e-06 27.5 1.3 0.68 10.3 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat NACHT PF05729.7 EFI27301.1 - 4.1e-05 23.3 0.0 0.00012 21.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EFI27301.1 - 0.00086 18.2 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EFI27301.1 - 0.0018 18.3 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EFI27301.1 - 0.019 14.9 0.0 0.047 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EFI27301.1 - 0.039 14.7 0.2 0.14 13.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EFI27301.1 - 0.19 12.0 1.7 0.62 10.3 1.0 2.0 1 1 0 1 1 1 0 AAA domain F-box-like PF12937.2 EFI27304.1 - 0.0024 17.5 0.2 0.0044 16.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like DUF2854 PF11016.3 EFI27308.1 - 0.052 13.0 0.4 0.12 11.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Cortex-I_coil PF09304.5 EFI27309.1 - 0.02 14.9 0.2 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil AAA_2 PF07724.9 EFI27311.1 - 1.2e-47 161.9 0.0 3.3e-46 157.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EFI27311.1 - 1.6e-21 76.8 0.2 1.6e-11 44.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EFI27311.1 - 5.1e-21 74.3 3.3 8.3e-21 73.6 0.2 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EFI27311.1 - 8.9e-16 57.8 0.0 6.9e-11 42.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EFI27311.1 - 4.5e-09 36.5 0.1 0.00051 20.1 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EFI27311.1 - 2.8e-08 33.9 1.7 0.0016 18.4 0.0 4.3 3 2 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EFI27311.1 - 3.9e-08 34.1 4.3 0.0015 19.3 0.0 3.6 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EFI27311.1 - 2.1e-07 30.5 0.0 2e-06 27.3 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EFI27311.1 - 1.7e-06 27.9 0.0 0.091 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EFI27311.1 - 1.7e-06 28.3 1.5 0.049 13.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain RuvB_N PF05496.7 EFI27311.1 - 0.00013 21.0 0.6 0.47 9.4 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 EFI27311.1 - 0.00014 21.5 0.0 0.032 13.9 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EFI27311.1 - 0.00021 20.5 0.1 0.37 9.9 0.0 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EFI27311.1 - 0.00029 20.9 0.0 0.51 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EFI27311.1 - 0.00034 20.5 0.6 1.9 8.4 0.0 4.1 4 1 0 4 4 3 1 AAA domain AAA_23 PF13476.1 EFI27311.1 - 0.00039 20.7 7.4 0.033 14.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EFI27311.1 - 0.00044 19.7 0.1 0.16 11.3 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 EFI27311.1 - 0.00052 19.7 0.0 0.43 10.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EFI27311.1 - 0.0015 18.7 1.3 0.058 13.6 0.0 3.2 3 0 0 3 3 3 1 ABC transporter NTPase_1 PF03266.10 EFI27311.1 - 0.0025 17.5 1.7 5.1 6.7 0.0 4.1 4 1 0 4 4 4 0 NTPase DNA_pol3_delta2 PF13177.1 EFI27311.1 - 0.0065 16.1 0.1 0.032 13.8 0.0 2.2 2 1 0 2 2 1 1 DNA polymerase III, delta subunit AAA_3 PF07726.6 EFI27311.1 - 0.0086 15.6 0.1 4.3 6.9 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EFI27311.1 - 0.0094 15.5 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein T2SE PF00437.15 EFI27311.1 - 0.012 14.5 0.0 0.027 13.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EFI27311.1 - 0.013 14.6 0.3 0.27 10.2 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.1 EFI27311.1 - 0.016 14.6 0.1 2.1 7.6 0.1 3.0 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EFI27311.1 - 0.027 14.3 0.0 4.7 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EFI27311.1 - 0.028 14.0 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EFI27311.1 - 0.029 13.8 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 EFI27311.1 - 0.031 14.2 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 EFI27311.1 - 0.044 13.4 0.0 4.6 6.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 EFI27311.1 - 0.059 12.9 0.0 0.75 9.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 EFI27311.1 - 0.071 12.6 0.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EFI27311.1 - 0.078 12.1 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 EFI27311.1 - 0.15 11.8 1.4 4.8 6.9 0.0 3.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EFI27311.1 - 0.16 11.6 7.1 4.2 6.9 0.0 3.9 3 2 0 3 3 3 0 Archaeal ATPase Seryl_tRNA_N PF02403.17 EFI27311.1 - 2 8.4 9.9 11 6.1 6.8 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EFI27311.1 - 2.3 7.2 6.9 4.2 6.3 4.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EFI27311.1 - 6 6.4 9.9 16 5.0 6.9 1.7 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EFI27313.1 - 6.4e-09 34.9 38.4 7.2e-06 24.9 8.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 EFI27313.1 - 0.063 13.4 4.0 3.7 7.6 0.1 3.0 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding MFS_1 PF07690.11 EFI27314.1 - 5.8e-14 51.5 12.5 7.5e-14 51.2 8.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MGC-24 PF05283.6 EFI27318.1 - 0.38 10.5 4.6 0.67 9.7 3.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) BacteriocIIc_cy PF12173.3 EFI27319.1 - 0.12 12.4 2.9 0.45 10.5 0.0 2.7 2 1 1 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like DUF2976 PF11190.3 EFI27319.1 - 6.4 6.3 6.6 4.7 6.8 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2976) Thioredoxin PF00085.15 EFI27320.1 - 1.1e-21 76.5 0.0 2.4e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EFI27320.1 - 4.1e-05 23.7 0.2 0.00018 21.6 0.1 2.0 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EFI27320.1 - 0.00018 21.5 0.0 0.0095 16.0 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EFI27320.1 - 0.00068 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EFI27320.1 - 0.018 14.7 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family ERp29_N PF07912.8 EFI27320.1 - 0.057 13.3 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 EFI27320.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like F-box-like PF12937.2 EFI27322.1 - 5.5e-10 38.8 3.1 5.5e-10 38.8 2.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EFI27322.1 - 0.0063 16.2 4.5 0.036 13.7 0.2 3.6 5 1 0 5 5 5 1 Leucine rich repeat F-box PF00646.28 EFI27322.1 - 0.036 13.7 8.3 4.9 6.9 0.1 3.9 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 EFI27323.1 - 0.0017 18.0 0.4 0.0017 18.0 0.3 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EFI27323.1 - 0.01 15.5 1.2 0.52 10.0 0.0 2.8 3 0 0 3 3 3 0 Leucine rich repeat COesterase PF00135.23 EFI27324.1 - 1.4e-58 198.9 0.0 2e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EFI27324.1 - 6.6e-05 22.5 0.6 0.00032 20.3 0.4 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold SH3_9 PF14604.1 EFI27325.1 - 9.1e-32 108.4 2.7 5.3e-16 57.9 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EFI27325.1 - 2.1e-25 87.8 3.7 3.1e-13 48.8 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EFI27325.1 - 5.4e-19 67.4 0.3 4e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EFI27325.1 - 2.8e-15 56.3 0.0 4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.4 EFI27325.1 - 0.18 11.5 0.1 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme PmbA_TldD PF01523.11 EFI27325.1 - 0.81 8.8 0.0 0.81 8.8 0.0 3.9 3 1 0 3 3 3 0 Putative modulator of DNA gyrase F-box-like PF12937.2 EFI27331.1 - 1.8e-09 37.1 0.2 3.5e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like ESCRT-II PF05871.7 EFI27334.1 - 4.3e-21 75.2 0.3 1.1e-20 74.0 0.2 1.6 1 0 0 1 1 1 1 ESCRT-II complex subunit FAD_binding_3 PF01494.14 EFI27335.1 - 7.4e-86 288.3 0.0 4.3e-85 285.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EFI27335.1 - 8.9e-19 67.7 0.0 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EFI27335.1 - 4.3e-06 25.4 0.1 6.7e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EFI27335.1 - 5.2e-06 25.5 0.4 8.6e-06 24.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EFI27335.1 - 7.6e-06 25.8 0.0 2.1e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EFI27335.1 - 1.2e-05 24.5 0.0 2.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EFI27335.1 - 1.9e-05 24.6 0.2 7.4e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EFI27335.1 - 0.00013 21.1 0.1 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EFI27335.1 - 0.00017 21.9 0.1 0.00074 19.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EFI27335.1 - 0.00018 20.5 0.1 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EFI27335.1 - 0.00034 20.2 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EFI27335.1 - 0.00035 19.5 0.2 0.00054 18.9 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EFI27335.1 - 0.0024 16.8 0.3 0.0053 15.7 0.2 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EFI27335.1 - 0.01 14.4 0.0 0.018 13.6 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EFI27335.1 - 0.011 15.8 0.1 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EFI27335.1 - 0.016 14.9 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.1 EFI27335.1 - 0.078 13.2 0.0 0.21 11.9 0.0 1.7 2 0 0 2 2 1 0 XdhC Rossmann domain CPSase_L_chain PF00289.17 EFI27335.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Shikimate_DH PF01488.15 EFI27335.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EFI27336.1 - 5.7e-82 275.6 0.0 1.1e-81 274.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EFI27336.1 - 1.9e-16 60.1 0.0 3.5e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EFI27336.1 - 1.3e-06 27.5 0.3 2.3e-06 26.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EFI27336.1 - 2.8e-06 27.2 0.0 7.7e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EFI27336.1 - 2.9e-06 26.0 0.2 4.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EFI27336.1 - 1.8e-05 24.3 0.0 3.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EFI27336.1 - 6.1e-05 22.9 0.0 0.00021 21.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EFI27336.1 - 9.6e-05 22.7 0.0 0.00093 19.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EFI27336.1 - 0.00017 20.8 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EFI27336.1 - 0.00018 20.7 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EFI27336.1 - 0.00021 20.2 0.2 0.00066 18.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EFI27336.1 - 0.00023 20.1 0.9 0.00036 19.5 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EFI27336.1 - 0.00043 19.2 0.2 0.00068 18.5 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EFI27336.1 - 0.0026 17.8 0.1 0.0069 16.4 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EFI27336.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain NAD_binding_9 PF13454.1 EFI27336.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding CPSase_L_chain PF00289.17 EFI27336.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 EFI27336.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain SE PF08491.5 EFI27336.1 - 0.049 12.4 0.0 7.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase UDPG_MGDP_dh_N PF03721.9 EFI27336.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EFI27336.1 - 0.088 12.9 0.1 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EFI27336.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EFI27336.1 - 0.11 12.3 0.2 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 ThiF family DNA_pol_delta_4 PF04081.8 EFI27337.1 - 9e-18 64.7 4.2 2.7e-17 63.2 2.9 1.9 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Adeno_PIX PF03955.9 EFI27337.1 - 0.31 11.5 5.8 6.2 7.3 0.4 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF572 PF04502.8 EFI27337.1 - 5.3 6.1 13.0 6.9 5.7 9.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) WLM PF08325.5 EFI27338.1 - 3.7e-39 134.5 0.8 2e-38 132.1 0.0 1.9 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.18 EFI27338.1 - 1.7e-08 33.7 0.0 3.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EFI27338.1 - 0.0029 17.8 0.0 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Peptidase_MA_2 PF13485.1 EFI27338.1 - 0.013 15.5 0.2 0.025 14.6 0.2 1.6 1 1 0 1 1 1 0 Peptidase MA superfamily DUF45 PF01863.12 EFI27338.1 - 0.13 12.0 1.2 0.21 11.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 Ytp1 PF10355.4 EFI27340.1 - 1.2e-71 241.0 8.1 2e-71 240.4 5.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EFI27340.1 - 1e-24 86.1 0.2 1e-24 86.1 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Rxt3 PF08642.5 EFI27340.1 - 0.0011 19.2 2.6 0.0023 18.1 0.0 2.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Tic20 PF09685.5 EFI27340.1 - 1.5 8.8 3.7 0.74 9.8 0.1 2.3 2 0 0 2 2 2 0 Tic20-like protein FHIPEP PF00771.15 EFI27340.1 - 5.7 5.1 0.6 12 4.0 0.4 1.5 1 0 0 1 1 1 0 FHIPEP family Lactamase_B_2 PF12706.2 EFI27341.1 - 2e-17 63.3 0.0 3.3e-16 59.4 0.0 2.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EFI27341.1 - 2.8e-08 33.0 0.0 2.9e-07 29.8 0.0 2.5 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.22 EFI27341.1 - 0.004 16.8 0.0 0.6 9.7 0.0 3.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Ion_trans PF00520.26 EFI27342.1 - 8.2e-19 67.6 16.5 8.2e-19 67.6 11.4 1.5 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EFI27342.1 - 2.3e-11 43.2 7.3 2.3e-11 43.2 5.0 2.7 2 2 0 2 2 2 1 Ion channel Lig_chan PF00060.21 EFI27342.1 - 0.0021 17.8 1.1 0.0021 17.8 0.7 2.1 2 0 0 2 2 2 1 Ligand-gated ion channel Cytochrom_C1 PF02167.10 EFI27342.1 - 0.14 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C1 family EVC2_like PF12297.3 EFI27342.1 - 0.18 10.3 0.6 8.5 4.8 0.6 2.3 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein CDP-OH_P_transf PF01066.16 EFI27343.1 - 2.7e-18 66.1 4.0 5.2e-18 65.2 2.8 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Glyco_hydro_61 PF03443.9 EFI27344.1 - 1.6e-30 106.5 0.0 2.2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 KH_1 PF00013.24 EFI27345.1 - 3.4e-08 33.0 0.1 5.2e-07 29.2 0.1 2.2 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EFI27345.1 - 1.4e-05 24.5 2.0 4.9e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 KH domain DUF1191 PF06697.7 EFI27346.1 - 0.1 11.3 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) VPS9 PF02204.13 EFI27347.1 - 6.9e-31 106.3 0.1 1.1e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EFI27347.1 - 1.1e-07 31.1 0.1 3.4e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 CUE domain DMA PF03474.9 EFI27347.1 - 0.0052 16.6 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif Sdh5 PF03937.11 EFI27349.1 - 2.6e-27 94.2 0.3 3.6e-27 93.8 0.2 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase ADH_N PF08240.7 EFI27350.1 - 1.5e-30 105.1 0.2 2.9e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EFI27350.1 - 4.7e-13 48.8 0.1 1.9e-09 37.1 0.0 2.7 3 0 0 3 3 3 2 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EFI27350.1 - 0.00029 20.4 0.0 0.00052 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI27350.1 - 0.017 15.7 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EFI27350.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 EFI27350.1 - 0.046 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FANCL_C PF11793.3 EFI27350.1 - 0.055 13.4 0.4 0.097 12.6 0.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Bd3614-deam PF14439.1 EFI27350.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase DUF4098 PF13345.1 EFI27352.1 - 0.096 12.6 0.5 2.1 8.3 0.4 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4098) WD40 PF00400.27 EFI27353.1 - 1.7e-42 141.8 13.1 1.8e-09 37.1 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EFI27353.1 - 0.01 14.5 0.0 0.23 10.1 0.0 2.3 3 0 0 3 3 3 0 Nup133 N terminal like Methyltransf_16 PF10294.4 EFI27354.1 - 4.2e-16 58.8 0.0 6.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EFI27354.1 - 2.9e-05 24.5 0.0 4.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI27354.1 - 0.05 13.1 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RED_N PF07808.8 EFI27355.1 - 7.4e-16 58.0 7.5 7.4e-16 58.0 5.2 2.4 3 0 0 3 3 3 1 RED-like protein N-terminal region GST_N_3 PF13417.1 EFI27356.1 - 1.1e-15 57.6 0.1 3.1e-15 56.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EFI27356.1 - 4.5e-13 48.9 0.0 9.8e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EFI27356.1 - 3.3e-06 27.0 0.0 7.4e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EFI27356.1 - 5e-05 23.0 0.0 0.00017 21.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EFI27356.1 - 0.0092 16.4 0.1 0.022 15.2 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EFI27356.1 - 0.01 15.9 0.0 0.052 13.7 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Fer4_20 PF14691.1 EFI27357.1 - 0.064 12.8 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DNA_ligase_A_M PF01068.16 EFI27358.1 - 2.7e-54 183.5 0.0 8.2e-54 182.0 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EFI27358.1 - 1.2e-37 129.3 0.1 2.1e-37 128.6 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 EFI27358.1 - 4e-12 46.1 1.0 1.1e-05 25.4 0.1 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 EFI27358.1 - 6.5e-10 39.2 0.0 2.9e-08 33.9 0.0 2.8 1 1 0 1 1 1 1 ATP dependent DNA ligase C terminal region PTCB-BRCT PF12738.2 EFI27358.1 - 0.014 15.1 0.1 6 6.8 0.0 2.9 3 0 0 3 3 3 0 twin BRCT domain Fork_head PF00250.13 EFI27359.1 - 8.3e-21 73.8 0.0 1.6e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain BRF1 PF07741.8 EFI27359.1 - 1.1 9.5 10.5 1.6 9.0 3.5 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CBM_5_12 PF02839.9 EFI27360.1 - 0.0063 16.0 0.0 0.032 13.8 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain ACC_central PF08326.7 EFI27362.1 - 1e-211 704.8 0.0 1.3e-211 704.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EFI27362.1 - 7.1e-169 562.2 0.0 9.7e-169 561.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EFI27362.1 - 8.2e-53 178.8 0.1 3.9e-52 176.5 0.0 2.1 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EFI27362.1 - 1.5e-25 89.3 0.1 3.5e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EFI27362.1 - 2.7e-21 75.5 0.0 5.1e-20 71.4 0.0 3.0 4 0 0 4 4 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EFI27362.1 - 1.2e-16 60.1 0.1 2.6e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EFI27362.1 - 7.2e-11 42.1 0.0 1.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EFI27362.1 - 1.9e-08 33.4 0.0 0.00078 18.2 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EFI27362.1 - 9.5e-05 21.8 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EFI27362.1 - 0.0004 20.2 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EFI27362.1 - 0.0024 17.5 0.0 0.0074 15.9 0.0 1.8 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp PF02222.17 EFI27362.1 - 0.048 13.0 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DUF1436 PF07262.6 EFI27362.1 - 0.24 10.8 0.0 0.79 9.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) NAD_synthase PF02540.12 EFI27363.1 - 4.9e-23 81.2 0.0 2.4e-22 79.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EFI27363.1 - 6.4e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 EFI27363.1 - 0.017 14.6 0.0 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 Asparagine synthase Mqo PF06039.10 EFI27363.1 - 0.041 12.0 0.0 0.074 11.2 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) zf-C2H2 PF00096.21 EFI27364.1 - 0.0073 16.5 0.1 0.017 15.4 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type Tropomyosin_1 PF12718.2 EFI27367.1 - 1.5e-31 109.2 38.2 1.5e-31 109.2 26.5 1.6 2 0 0 2 2 2 1 Tropomyosin like Tropomyosin PF00261.15 EFI27367.1 - 1.1e-06 27.8 43.9 2.2e-05 23.6 17.4 2.7 2 1 1 3 3 3 2 Tropomyosin TMF_DNA_bd PF12329.3 EFI27367.1 - 0.015 15.1 20.1 0.015 15.1 13.9 4.0 3 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 EFI27367.1 - 0.13 11.1 35.7 0.05 12.5 13.5 3.0 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EFI27367.1 - 0.79 8.7 44.1 0.01 14.9 16.5 2.7 2 1 1 3 3 3 0 Autophagy protein Apg6 GAS PF13851.1 EFI27367.1 - 1.8 7.7 41.7 13 4.9 14.9 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EFI27367.1 - 3.7 5.9 30.8 2.1 6.7 18.2 2.0 1 1 0 2 2 2 0 AAA domain DUF2125 PF09898.4 EFI27367.1 - 5.7 6.1 9.2 2 7.6 4.1 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) Effector_1 PF04518.7 EFI27367.1 - 6 5.7 16.4 1.2 8.0 1.1 2.4 1 1 1 2 2 2 0 Effector from type III secretion system Reo_sigmaC PF04582.7 EFI27367.1 - 7.9 5.5 6.7 15 4.6 0.4 2.8 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EFI27367.1 - 7.9 6.2 18.2 0.42 10.4 5.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 EFI27367.1 - 9 6.3 19.0 5.3 7.1 1.4 4.4 2 1 2 4 4 4 0 Proteins of 100 residues with WXG Synaptobrevin PF00957.16 EFI27367.1 - 9.3 5.9 17.9 0.11 12.1 0.3 3.5 3 1 1 4 4 4 0 Synaptobrevin Tropomyosin PF00261.15 EFI27368.1 - 7.4e-07 28.4 16.4 3.7e-06 26.2 11.3 1.8 1 1 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.2 EFI27368.1 - 5e-05 23.1 16.0 0.01 15.6 2.7 2.1 1 1 1 2 2 2 2 Tropomyosin like ERM PF00769.14 EFI27368.1 - 0.00023 20.7 14.3 0.0003 20.4 2.5 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DUF4201 PF13870.1 EFI27368.1 - 0.00024 20.6 15.3 0.00064 19.2 3.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Laminin_II PF06009.7 EFI27368.1 - 0.0016 18.1 8.3 0.0031 17.2 4.9 2.0 1 1 0 1 1 1 1 Laminin Domain II Filament PF00038.16 EFI27368.1 - 0.0024 17.4 10.4 0.12 11.8 2.2 2.0 1 1 1 2 2 2 2 Intermediate filament protein ATG16 PF08614.6 EFI27368.1 - 0.0036 17.1 17.1 0.0045 16.8 4.8 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) AAA_27 PF13514.1 EFI27368.1 - 0.0072 14.0 12.1 0.0083 13.8 8.4 1.0 1 0 0 1 1 1 1 AAA domain Cortex-I_coil PF09304.5 EFI27368.1 - 0.0079 16.2 14.3 0.15 12.1 9.3 2.2 1 1 0 1 1 1 1 Cortexillin I, coiled coil Cast PF10174.4 EFI27368.1 - 0.0089 14.1 16.0 0.016 13.2 11.1 1.4 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone CCDC155 PF14662.1 EFI27368.1 - 0.013 15.0 14.0 0.07 12.7 9.7 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Myosin_tail_1 PF01576.14 EFI27368.1 - 0.015 13.0 14.7 0.021 12.5 10.2 1.2 1 0 0 1 1 1 0 Myosin tail Prefoldin_2 PF01920.15 EFI27368.1 - 0.016 14.9 15.3 0.19 11.4 3.2 2.9 1 1 2 3 3 3 0 Prefoldin subunit EzrA PF06160.7 EFI27368.1 - 0.021 13.0 11.9 3.5 5.7 8.3 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 EFI27368.1 - 0.035 14.2 7.2 0.055 13.5 5.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EFI27368.1 - 0.037 13.6 14.1 0.35 10.4 9.8 1.9 1 1 0 1 1 1 0 IncA protein AAA_13 PF13166.1 EFI27368.1 - 0.039 12.4 8.7 0.045 12.2 6.1 1.1 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 EFI27368.1 - 0.043 14.1 11.0 0.19 12.0 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Matrilin_ccoil PF10393.4 EFI27368.1 - 0.044 13.1 4.2 0.15 11.4 0.4 3.4 1 1 2 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Nup54 PF13874.1 EFI27368.1 - 0.054 13.1 9.6 0.15 11.6 1.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 EFI27368.1 - 0.064 13.0 15.6 0.9 9.2 10.8 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EFI27368.1 - 0.064 13.3 9.0 1.4 9.1 5.6 2.2 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PilJ PF13675.1 EFI27368.1 - 0.067 13.5 2.9 0.21 11.9 1.3 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Tektin PF03148.9 EFI27368.1 - 0.073 11.6 10.1 0.36 9.3 1.1 2.2 2 0 0 2 2 2 0 Tektin family PspA_IM30 PF04012.7 EFI27368.1 - 0.087 12.1 12.5 0.16 11.3 8.6 1.4 1 1 0 1 1 1 0 PspA/IM30 family Mnd1 PF03962.10 EFI27368.1 - 0.093 12.3 13.5 0.28 10.8 2.6 2.0 1 1 1 2 2 2 0 Mnd1 family Vps5 PF09325.5 EFI27368.1 - 0.094 11.9 8.1 0.028 13.6 0.9 2.0 1 1 1 2 2 2 0 Vps5 C terminal like GAS PF13851.1 EFI27368.1 - 0.12 11.5 14.2 0.32 10.1 10.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 EFI27368.1 - 0.13 12.2 15.9 0.14 12.1 3.1 2.7 1 1 3 4 4 3 0 bZIP transcription factor Spc7 PF08317.6 EFI27368.1 - 0.14 10.8 13.4 0.15 10.6 9.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.3 EFI27368.1 - 0.19 9.0 11.9 0.31 8.3 8.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EFI27368.1 - 0.21 10.5 13.2 0.37 9.8 9.2 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 Vac_Fusion PF02346.11 EFI27368.1 - 0.22 10.9 3.7 4 6.9 0.3 3.0 2 1 1 3 3 3 0 Chordopoxvirus fusion protein CALCOCO1 PF07888.6 EFI27368.1 - 0.22 9.7 11.1 0.26 9.5 2.4 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.3 EFI27368.1 - 0.22 11.3 15.1 0.31 10.9 2.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EFI27368.1 - 0.28 10.3 1.2 0.6 9.2 0.7 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein MIF4G_like_2 PF09090.6 EFI27368.1 - 0.3 10.2 5.8 0.36 10.0 4.0 1.1 1 0 0 1 1 1 0 MIF4G like Baculo_PEP_C PF04513.7 EFI27368.1 - 0.3 10.9 3.4 0.42 10.4 0.4 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 EFI27368.1 - 0.3 10.9 18.2 2.2 8.1 3.8 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Bacillus_HBL PF05791.6 EFI27368.1 - 0.31 10.3 6.3 0.22 10.8 3.0 1.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) LKAAEAR PF15478.1 EFI27368.1 - 0.35 11.1 4.6 0.98 9.6 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function with LKAAEAR motif DUF3847 PF12958.2 EFI27368.1 - 0.35 10.6 12.7 0.19 11.5 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3847) STAT_alpha PF01017.15 EFI27368.1 - 0.37 10.5 8.5 1.5 8.5 1.9 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain DUF1664 PF07889.7 EFI27368.1 - 0.38 10.5 8.4 1.3 8.7 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4315 PF14193.1 EFI27368.1 - 0.38 10.7 9.8 2.3 8.2 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) GreA_GreB_N PF03449.10 EFI27368.1 - 0.39 10.8 0.2 0.39 10.8 0.1 3.7 3 1 2 5 5 5 0 Transcription elongation factor, N-terminal DUF2408 PF10303.4 EFI27368.1 - 0.42 10.7 8.2 0.31 11.1 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DASH_Dam1 PF08653.5 EFI27368.1 - 0.43 10.3 2.0 1.2 9.0 0.2 2.2 2 1 0 2 2 2 0 DASH complex subunit Dam1 MutS_III PF05192.13 EFI27368.1 - 0.46 10.2 3.8 0.57 9.9 2.7 1.1 1 0 0 1 1 1 0 MutS domain III DUF4200 PF13863.1 EFI27368.1 - 0.46 10.4 16.6 37 4.2 11.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Uds1 PF15456.1 EFI27368.1 - 0.47 10.4 11.8 1.4 8.9 6.8 2.1 1 1 1 2 2 2 0 Up-regulated During Septation Ax_dynein_light PF10211.4 EFI27368.1 - 0.51 10.1 12.1 0.77 9.5 1.7 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4472 PF14739.1 EFI27368.1 - 0.54 10.7 10.1 0.32 11.4 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF812 PF05667.6 EFI27368.1 - 0.66 8.4 10.6 4.5 5.6 7.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Sec34 PF04136.10 EFI27368.1 - 0.78 9.4 5.9 3.5 7.3 0.9 2.0 1 1 1 2 2 2 0 Sec34-like family UPF0449 PF15136.1 EFI27368.1 - 0.83 9.8 8.8 22 5.3 6.1 2.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 THOC7 PF05615.8 EFI27368.1 - 0.84 9.9 13.9 0.27 11.4 3.1 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4140 PF13600.1 EFI27368.1 - 1.1 9.7 11.9 5.6e+02 1.0 0.0 3.0 1 1 1 2 2 1 0 N-terminal domain of unknown function (DUF4140) DUF489 PF04356.7 EFI27368.1 - 1.1 8.8 4.6 4.2 6.9 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) DUF2730 PF10805.3 EFI27368.1 - 1.1 9.0 5.7 31 4.3 3.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.10 EFI27368.1 - 1.2 8.6 18.0 1.5 8.4 2.4 3.5 1 1 2 3 3 3 0 Septum formation initiator Prefoldin PF02996.12 EFI27368.1 - 1.3 8.7 13.5 1.2 8.7 1.2 2.8 1 1 2 3 3 3 0 Prefoldin subunit TBPIP PF07106.8 EFI27368.1 - 1.3 8.5 13.1 3.7 7.0 3.8 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3053 PF11254.3 EFI27368.1 - 1.4 8.1 7.1 5.5 6.1 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) NPV_P10 PF05531.7 EFI27368.1 - 1.6 9.0 5.9 95 3.3 4.1 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 EFI27368.1 - 1.6 6.4 11.7 1.6 6.4 2.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family XhlA PF10779.4 EFI27368.1 - 1.8 8.5 14.1 2.1 8.3 1.8 2.8 1 1 2 3 3 3 0 Haemolysin XhlA Macoilin PF09726.4 EFI27368.1 - 2.2 6.4 13.2 2.6 6.2 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Cluap1 PF10234.4 EFI27368.1 - 2.3 7.3 13.1 3 6.9 1.7 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF904 PF06005.7 EFI27368.1 - 2.4 8.5 16.2 6.7 7.0 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) UPF0184 PF03670.8 EFI27368.1 - 2.7 8.2 7.4 1.4 9.1 0.2 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Cep57_MT_bd PF06657.8 EFI27368.1 - 2.7 7.9 8.8 2.3 8.2 1.4 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 EFI27368.1 - 2.9 8.1 12.4 4.9e+02 0.9 8.6 2.5 1 1 0 1 1 1 0 Syntaxin DUF4337 PF14235.1 EFI27368.1 - 3 7.6 9.6 2.9 7.7 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF3373 PF11853.3 EFI27368.1 - 3 6.2 9.7 0.77 8.2 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) COG2 PF06148.6 EFI27368.1 - 4.1 7.2 8.8 1.9 8.3 1.5 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.7 EFI27368.1 - 4.3 7.7 10.8 6.8 7.1 1.6 3.1 1 1 2 3 3 3 0 SlyX FemAB PF02388.11 EFI27368.1 - 4.3 5.9 8.3 4.5 5.8 0.9 2.0 1 1 1 2 2 2 0 FemAB family Phage_GP20 PF06810.6 EFI27368.1 - 5 6.5 13.5 3.8 6.9 3.8 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF4164 PF13747.1 EFI27368.1 - 5.2 7.2 16.7 5.7 7.1 3.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Nsp1_C PF05064.8 EFI27368.1 - 5.2 6.7 8.4 16 5.1 3.9 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region PspB PF06667.7 EFI27368.1 - 5.7 6.9 6.5 11 6.0 0.2 2.8 1 1 2 3 3 3 0 Phage shock protein B DUF342 PF03961.8 EFI27368.1 - 6.4 5.0 10.7 17 3.6 7.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 EFI27368.1 - 6.5 5.6 13.4 11 4.8 9.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Kinetocho_Slk19 PF12709.2 EFI27368.1 - 9.7 6.3 12.6 1.8 8.6 0.6 3.3 1 1 2 3 3 3 0 Central kinetochore-associated zf-DHHC PF01529.15 EFI27369.1 - 1e-21 77.0 0.1 1e-21 77.0 0.0 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DsbB PF02600.11 EFI27369.1 - 0.23 11.2 4.5 0.06 13.1 0.6 1.9 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB TctB PF07331.6 EFI27369.1 - 5.1 6.7 11.7 0.33 10.5 4.0 1.9 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Glyco_hydro_47 PF01532.15 EFI27370.1 - 3.4e-128 428.1 0.0 4e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.8 EFI27371.1 - 1.8e-30 104.7 0.1 3.9e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Erv1 / Alr family SHNi-TPR PF10516.4 EFI27373.1 - 8.6e-17 60.1 0.1 4.2e-14 51.5 0.0 2.5 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.1 EFI27373.1 - 9.1e-15 54.3 5.7 1.1e-06 28.5 0.6 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EFI27373.1 - 2.7e-14 52.5 0.3 1.1e-06 28.1 0.2 2.6 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EFI27373.1 - 1.5e-07 30.7 0.3 0.019 14.5 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EFI27373.1 - 2.7e-07 29.9 5.1 0.017 14.9 0.6 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EFI27373.1 - 2.7e-06 27.8 14.4 0.00063 20.3 0.9 3.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EFI27373.1 - 0.00021 21.5 9.1 0.59 10.5 0.2 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EFI27373.1 - 0.002 17.9 1.1 0.23 11.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EFI27373.1 - 0.0024 17.5 3.3 2.4 8.1 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EFI27373.1 - 0.0058 16.3 5.0 1.3 9.0 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EFI27373.1 - 0.0066 16.9 7.6 11 7.0 0.4 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Sec5 PF15469.1 EFI27373.1 - 0.01 15.5 2.1 0.31 10.7 0.2 2.5 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF1664 PF07889.7 EFI27373.1 - 0.046 13.5 0.2 0.13 12.0 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) MIT PF04212.13 EFI27373.1 - 0.18 11.6 7.7 1.3 8.9 0.6 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain FUSC PF04632.7 EFI27373.1 - 0.23 9.8 1.2 0.39 9.0 0.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rox3 PF08633.5 EFI27373.1 - 0.36 11.1 6.8 0.39 10.9 3.2 2.1 2 1 0 2 2 2 0 Rox3 mediator complex subunit NYD-SP12_N PF15015.1 EFI27373.1 - 8.1 4.5 9.7 0.43 8.7 0.1 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal KorB PF08535.5 EFI27374.1 - 0.082 13.0 0.0 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 KorB domain CNH PF00780.17 EFI27376.1 - 1.2e-77 261.0 0.0 1.8e-77 260.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EFI27376.1 - 2.7e-38 130.9 0.1 5.6e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EFI27376.1 - 8.3e-33 113.7 0.0 2e-32 112.4 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EFI27376.1 - 1.7e-12 46.9 0.2 4.2e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.16 EFI27377.1 - 1.4e-52 178.5 2.9 9.8e-33 113.4 1.3 2.0 2 0 0 2 2 2 2 Cation efflux family EamA PF00892.15 EFI27378.1 - 0.029 14.4 4.3 0.058 13.4 2.7 1.7 1 1 1 2 2 2 0 EamA-like transporter family CHCH PF06747.8 EFI27381.1 - 2.1e-06 27.5 3.5 2.8e-06 27.0 2.5 1.2 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.12 EFI27381.1 - 0.00026 20.9 3.5 0.00035 20.5 2.4 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DUF1903 PF08991.5 EFI27381.1 - 0.00054 20.0 2.5 0.00075 19.6 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Pet191_N PF10203.4 EFI27381.1 - 0.022 14.7 1.8 0.03 14.3 1.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 EFI27381.1 - 0.036 13.8 2.7 0.097 12.5 1.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Nitroreductase PF00881.19 EFI27382.1 - 1.1e-25 90.4 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Ctr PF04145.10 EFI27383.1 - 1.3e-28 99.8 0.0 1.6e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Pheromone PF08015.6 EFI27384.1 - 5.8e-06 27.0 1.3 0.00032 21.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Ank PF00023.25 EFI27385.1 - 5.3e-21 73.3 0.2 4.3e-05 23.0 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EFI27385.1 - 2.2e-20 72.7 0.0 2.2e-12 47.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EFI27385.1 - 3.3e-13 49.4 0.1 5.6e-08 32.7 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EFI27385.1 - 6.8e-12 44.4 0.0 0.025 14.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EFI27385.1 - 7.2e-12 45.4 0.0 1.1e-07 32.1 0.0 2.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.9 EFI27389.1 - 2.2e-15 57.0 0.1 2.9e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EFI27389.1 - 5.1e-13 49.2 1.3 1e-09 38.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EFI27389.1 - 7.3e-07 29.0 0.1 0.18 11.5 0.0 3.4 3 0 0 3 3 3 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EFI27389.1 - 1.7e-06 28.2 0.0 0.001 19.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EFI27389.1 - 3.7e-05 23.9 0.2 0.073 13.3 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding DAO PF01266.19 EFI27389.1 - 0.00097 18.1 10.4 0.86 8.4 0.4 4.0 2 2 1 4 4 4 3 FAD dependent oxidoreductase TrkA_N PF02254.13 EFI27389.1 - 0.0014 18.6 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain K_oxygenase PF13434.1 EFI27389.1 - 0.0029 16.5 0.0 0.77 8.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EFI27389.1 - 0.15 10.6 0.9 3.5 6.1 0.1 2.9 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 EFI27389.1 - 6.8 5.4 7.6 13 4.5 0.0 3.3 5 0 0 5 5 5 0 Glucose inhibited division protein A AAA PF00004.24 EFI27390.1 - 8.7e-43 145.6 0.0 4.1e-16 59.3 0.0 5.4 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EFI27390.1 - 5.9e-34 117.1 0.0 3.7e-33 114.6 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EFI27390.1 - 1.8e-32 112.7 15.8 1.2e-26 93.7 0.0 6.5 6 0 0 6 6 5 3 AAA domain AAA_19 PF13245.1 EFI27390.1 - 1e-19 70.0 2.3 1.2e-05 24.9 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_17 PF13207.1 EFI27390.1 - 6.2e-15 56.0 19.8 0.0034 18.1 0.0 7.3 8 0 0 8 8 5 4 AAA domain AAA_22 PF13401.1 EFI27390.1 - 1.2e-14 54.5 7.5 0.0072 16.4 0.0 7.7 6 2 0 6 6 5 4 AAA domain AAA_5 PF07728.9 EFI27390.1 - 1.1e-13 51.1 0.4 0.042 13.5 0.0 5.1 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EFI27390.1 - 3.7e-11 42.5 0.0 0.026 13.5 0.0 4.9 4 1 0 4 4 4 3 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EFI27390.1 - 4.3e-11 42.8 3.0 0.059 13.2 0.0 5.2 4 0 0 4 4 4 3 AAA domain IstB_IS21 PF01695.12 EFI27390.1 - 7.7e-11 41.7 0.1 0.074 12.4 0.0 4.7 4 0 0 4 4 4 3 IstB-like ATP binding protein AAA_18 PF13238.1 EFI27390.1 - 1.3e-10 41.7 10.5 0.094 13.0 0.1 5.8 5 0 0 5 5 4 4 AAA domain Mg_chelatase PF01078.16 EFI27390.1 - 1.3e-10 40.7 0.1 0.11 11.6 0.0 4.6 4 0 0 4 4 4 3 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EFI27390.1 - 4.3e-10 39.7 0.1 0.86 9.8 0.0 5.2 4 0 0 4 4 4 3 RNA helicase Viral_helicase1 PF01443.13 EFI27390.1 - 5.1e-10 39.2 0.1 0.1 12.0 0.0 6.2 5 1 0 5 5 5 3 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EFI27390.1 - 3.9e-09 36.7 24.0 0.035 14.0 0.0 6.4 7 0 0 7 7 4 4 AAA ATPase domain AAA_25 PF13481.1 EFI27390.1 - 2.7e-08 33.4 8.8 0.066 12.6 0.0 5.3 5 0 0 5 5 4 2 AAA domain PhoH PF02562.11 EFI27390.1 - 4.8e-07 29.2 0.6 2.4 7.3 0.0 5.3 5 0 0 5 5 5 1 PhoH-like protein AAA_24 PF13479.1 EFI27390.1 - 1.6e-06 27.9 5.0 1.3 8.5 0.1 5.2 5 0 0 5 5 5 2 AAA domain Torsin PF06309.6 EFI27390.1 - 1e-05 25.4 0.1 13 5.6 0.0 5.3 5 0 0 5 5 5 0 Torsin AAA_14 PF13173.1 EFI27390.1 - 1.2e-05 25.1 0.0 0.57 10.0 0.0 4.9 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.21 EFI27390.1 - 1.4e-05 24.6 0.0 4.5 6.7 0.0 4.9 4 1 0 4 4 4 0 Sigma-54 interaction domain VirE PF05272.6 EFI27390.1 - 0.0001 21.8 0.0 0.00052 19.5 0.0 2.2 2 0 0 2 2 1 1 Virulence-associated protein E KTI12 PF08433.5 EFI27390.1 - 0.00033 19.9 0.8 4.8 6.3 0.0 4.2 4 0 0 4 4 4 0 Chromatin associated protein KTI12 NACHT PF05729.7 EFI27390.1 - 0.00047 19.8 0.5 12 5.5 0.0 4.5 4 0 0 4 4 4 0 NACHT domain Sigma54_activ_2 PF14532.1 EFI27390.1 - 0.00065 19.7 0.1 14 5.6 0.0 4.7 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_28 PF13521.1 EFI27390.1 - 0.00071 19.5 26.4 0.05 13.5 0.0 6.8 7 1 1 8 8 6 3 AAA domain AAA_29 PF13555.1 EFI27390.1 - 0.0011 18.4 0.5 7.7 6.1 0.0 4.4 4 0 0 4 4 4 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EFI27390.1 - 0.0023 17.6 5.1 0.59 9.8 0.0 4.4 5 0 0 5 5 4 1 NTPase MobB PF03205.9 EFI27390.1 - 0.0029 17.3 0.1 19 4.9 0.0 4.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 EFI27390.1 - 0.0038 16.2 26.8 0.0069 15.3 0.0 7.5 7 1 0 7 7 5 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EFI27390.1 - 0.015 14.7 14.1 3.4 7.0 0.1 6.7 6 1 0 7 7 6 0 AAA-like domain ADK PF00406.17 EFI27390.1 - 0.018 14.8 2.1 33 4.3 0.1 4.0 3 0 0 3 3 3 0 Adenylate kinase PIF1 PF05970.9 EFI27390.1 - 0.02 13.8 0.0 0.42 9.4 0.0 2.8 2 0 0 2 2 2 0 PIF1-like helicase 6PF2K PF01591.13 EFI27390.1 - 0.02 13.9 0.0 2.8 6.9 0.0 3.1 3 0 0 3 3 3 0 6-phosphofructo-2-kinase Parvo_NS1 PF01057.12 EFI27390.1 - 0.033 13.0 0.0 3.1 6.5 0.0 3.5 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 SRP54 PF00448.17 EFI27390.1 - 0.037 13.4 0.0 0.037 13.4 0.0 4.9 6 0 0 6 6 4 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EFI27390.1 - 0.12 11.4 9.8 5.5 6.0 0.0 4.7 5 0 0 5 5 4 0 KaiC cobW PF02492.14 EFI27390.1 - 0.3 10.4 4.5 19 4.6 0.0 4.6 5 0 0 5 5 4 0 CobW/HypB/UreG, nucleotide-binding domain ADH_zinc_N PF00107.21 EFI27391.1 - 4.6e-14 52.0 0.0 1.2e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EFI27391.1 - 0.00031 21.6 0.0 0.00089 20.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EFI27391.1 - 0.0082 15.8 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NmrA PF05368.8 EFI27391.1 - 0.04 13.1 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EFI27391.1 - 0.072 13.0 0.1 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase DNA_ligase_A_M PF01068.16 EFI27392.1 - 4.9e-22 78.2 0.0 9.7e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EFI27392.1 - 3.8e-15 56.1 0.0 7.3e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus Pkinase PF00069.20 EFI27394.1 - 7.2e-52 176.1 0.0 1.2e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27394.1 - 5.4e-20 71.5 0.0 2.4e-19 69.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EFI27394.1 - 0.036 13.8 3.0 0.14 11.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family MCPVI PF02993.9 EFI27394.1 - 3 7.9 6.9 5.5 7.0 4.8 1.3 1 0 0 1 1 1 0 Minor capsid protein VI NTF2 PF02136.15 EFI27396.1 - 0.047 14.0 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain ZZ PF00569.12 EFI27397.1 - 7.3e-19 67.0 48.2 4.7e-08 32.4 1.2 6.4 6 0 0 6 6 6 5 Zinc finger, ZZ type PB1 PF00564.19 EFI27397.1 - 7.9e-08 31.8 0.0 2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PHF5 PF03660.9 EFI27398.1 - 3.8e-33 113.7 2.1 5.1e-33 113.3 1.4 1.1 1 0 0 1 1 1 1 PHF5-like protein PHD PF00628.24 EFI27398.1 - 0.1 12.3 1.9 0.19 11.4 1.3 1.5 1 0 0 1 1 1 0 PHD-finger DZR PF12773.2 EFI27398.1 - 0.4 10.5 6.4 0.46 10.3 3.5 1.8 1 1 0 1 1 1 0 Double zinc ribbon PolC_DP2 PF03833.8 EFI27398.1 - 0.87 7.1 2.4 1 6.9 1.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 C1_3 PF07649.7 EFI27398.1 - 1 9.4 9.1 1.5 8.9 2.8 2.4 2 0 0 2 2 2 0 C1-like domain Tnp_zf-ribbon_2 PF13842.1 EFI27398.1 - 5.3 7.5 6.0 1.7 9.1 1.0 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon LMBR1 PF04791.11 EFI27399.1 - 0.0024 16.5 6.0 0.0029 16.2 4.1 1.2 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF2231 PF09990.4 EFI27399.1 - 0.28 11.5 1.8 0.52 10.6 0.5 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) Abhydrolase_9_N PF15420.1 EFI27399.1 - 0.57 9.9 4.4 0.68 9.6 3.1 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Aminotran_3 PF00202.16 EFI27400.1 - 1.1e-74 251.2 0.0 1.6e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HECT PF00632.20 EFI27401.1 - 2.6e-83 279.8 0.0 3.8e-83 279.2 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EFI27401.1 - 0.05 13.4 1.8 0.77 9.6 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat SDH_alpha PF03313.10 EFI27403.1 - 1.3e-74 250.8 1.6 7.6e-47 159.6 0.0 2.3 2 0 0 2 2 2 2 Serine dehydratase alpha chain SDH_beta PF03315.10 EFI27403.1 - 4.9e-57 192.4 0.0 9.3e-57 191.5 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain Peptidase_M20 PF01546.23 EFI27408.1 - 1.6e-28 99.4 0.0 2.4e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EFI27408.1 - 1.8e-11 43.7 0.0 3.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EFI27408.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Ribosomal_L37ae PF01780.14 EFI27409.1 - 2.9e-17 62.3 0.9 3.2e-17 62.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1364 PF07102.7 EFI27409.1 - 0.0067 16.2 0.6 0.0074 16.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) AAA_33 PF13671.1 EFI27411.1 - 3.5e-08 33.4 0.0 2.5e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain Velvet PF11754.3 EFI27412.1 - 5.5e-11 42.4 0.0 7.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Pheromone PF08015.6 EFI27413.1 - 5.8e-06 27.0 1.3 0.00032 21.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI27414.1 - 2.4e-05 25.0 1.4 0.0013 19.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone HAUS6_N PF14661.1 EFI27419.1 - 5.3e-07 29.2 0.0 0.00035 20.0 0.0 2.5 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 6 N-terminus RINGv PF12906.2 EFI27420.1 - 5.9e-16 58.2 7.9 1.1e-15 57.4 5.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EFI27420.1 - 0.1 12.4 8.7 0.2 11.5 6.0 1.5 1 0 0 1 1 1 0 Ring finger domain HEAT_EZ PF13513.1 EFI27424.1 - 0.0035 17.7 0.2 0.0066 16.9 0.1 1.4 1 0 0 1 1 1 1 HEAT-like repeat Anoctamin PF04547.7 EFI27426.1 - 3.9e-97 325.7 0.3 5.3e-97 325.3 0.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel p450 PF00067.17 EFI27427.1 - 1.1e-15 57.1 0.0 1.1e-15 57.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EFI27428.1 - 7.7e-07 27.9 0.0 9.3e-07 27.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EFI27429.1 - 6.3e-40 136.9 28.0 8.7e-40 136.5 19.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EFI27429.1 - 0.00063 17.9 3.3 0.0037 15.3 2.3 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EFI27429.1 - 0.00093 18.9 0.6 0.0036 17.0 0.4 2.1 1 0 0 1 1 1 1 MFS_1 like family Metallothio_2 PF01439.13 EFI27430.1 - 0.00098 19.6 8.4 0.00098 19.6 5.8 2.4 2 0 0 2 2 2 1 Metallothionein Metallothio_PEC PF02068.11 EFI27430.1 - 0.12 12.7 33.2 0.26 11.6 23.0 1.6 1 1 0 1 1 1 0 Plant PEC family metallothionein Metallothio_Euk PF12749.2 EFI27430.1 - 0.27 11.3 34.0 0.34 10.9 23.6 1.2 1 0 0 1 1 1 0 Eukaryotic metallothionein Metallothio PF00131.15 EFI27430.1 - 2.3 8.1 41.1 7.7 6.4 28.5 1.8 1 1 0 1 1 1 0 Metallothionein PC-Esterase PF13839.1 EFI27431.1 - 3.5e-09 36.8 2.7 2.3e-08 34.2 1.3 2.4 2 1 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p ZZ PF00569.12 EFI27432.1 - 0.00064 19.2 13.2 0.00064 19.2 9.1 2.5 2 0 0 2 2 2 1 Zinc finger, ZZ type DUF2201_N PF13203.1 EFI27432.1 - 0.016 14.3 0.1 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Pro_isomerase PF00160.16 EFI27439.1 - 1e-19 71.3 0.0 1.1e-19 71.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ank_2 PF12796.2 EFI27440.1 - 3e-32 110.7 0.1 1.2e-10 41.5 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EFI27440.1 - 1.2e-15 56.4 6.1 0.00011 21.8 0.1 6.2 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EFI27440.1 - 1.4e-15 56.9 1.1 4.5e-07 29.9 0.0 4.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EFI27440.1 - 1.2e-11 43.6 0.6 0.013 15.6 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EFI27440.1 - 2.8e-10 40.4 1.4 0.00036 20.9 0.0 4.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Bac_chlorC PF02043.12 EFI27448.1 - 0.055 13.2 0.1 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein PROL5-SMR PF15621.1 EFI27448.1 - 0.31 11.5 3.3 3.2 8.2 3.0 1.8 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Polysacc_deac_1 PF01522.16 EFI27453.1 - 9.9e-28 96.2 0.0 1.7e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase ICMT PF04140.9 EFI27454.1 - 1.3e-07 31.6 1.8 3.9e-07 30.1 0.4 2.0 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EFI27454.1 - 5.1e-05 23.3 1.6 0.00026 21.0 0.1 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EFI27454.1 - 0.0015 17.1 0.1 0.0094 14.5 0.1 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EFI27454.1 - 0.13 11.4 0.0 1.5 8.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) DUF4472 PF14739.1 EFI27456.1 - 0.074 13.5 0.6 0.9 10.0 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF2730 PF10805.3 EFI27456.1 - 0.092 12.4 0.8 1.7 8.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Tet_JBP PF12851.2 EFI27457.1 - 1.1e-12 47.5 0.0 2.2e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EFI27457.1 - 0.046 14.2 0.1 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF2527 PF10736.4 EFI27459.1 - 0.04 13.5 0.2 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) BCL_N PF04714.8 EFI27461.1 - 1.7 8.2 5.7 0.86 9.2 1.4 2.2 2 0 0 2 2 2 0 BCL7, N-terminal conserver region CcmD PF04995.9 EFI27462.1 - 1.4 8.7 4.0 2.5 7.9 2.8 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) MGC-24 PF05283.6 EFI27463.1 - 0.021 14.6 0.2 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) EphA2_TM PF14575.1 EFI27464.1 - 0.0046 17.3 0.1 0.0088 16.4 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 EFI27464.1 - 0.0068 16.0 0.1 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Protocadherin TMEM154 PF15102.1 EFI27464.1 - 0.035 13.8 0.2 0.087 12.5 0.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 EFI27464.1 - 0.11 12.0 1.2 0.2 11.2 0.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 IncA PF04156.9 EFI27464.1 - 0.17 11.4 0.3 0.26 10.8 0.2 1.1 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 EFI27464.1 - 0.28 9.3 2.2 0.76 7.9 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF2464 PF10240.4 EFI27464.1 - 8.5 5.6 6.4 16 4.7 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) Alpha_GJ PF03229.8 EFI27466.1 - 0.15 12.3 4.3 0.25 11.6 1.3 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J TMEM154 PF15102.1 EFI27467.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Big_2 PF02368.13 EFI27467.1 - 2.2 8.2 12.7 3.7 7.4 0.4 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Adap_comp_sub PF00928.16 EFI27469.1 - 9.5e-89 296.9 0.0 1.4e-88 296.4 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EFI27469.1 - 2.9e-07 30.3 0.3 4.9e-07 29.5 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 EFI27469.1 - 0.0087 14.7 0.0 0.012 14.1 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 SH3_5 PF08460.5 EFI27469.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain Dyp_perox PF04261.7 EFI27470.1 - 2.4e-07 29.8 0.0 1e-06 27.7 0.0 2.1 2 1 0 2 2 2 1 Dyp-type peroxidase family PDH PF02153.12 EFI27473.1 - 2.7e-14 52.6 0.0 3.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EFI27473.1 - 5.6e-08 33.1 0.0 1.4e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EFI27473.1 - 2.4e-06 27.5 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EFI27473.1 - 0.00016 21.8 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EFI27473.1 - 0.00077 19.2 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family ApbA PF02558.11 EFI27473.1 - 0.0016 17.8 0.0 0.0038 16.6 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EFI27473.1 - 0.0042 16.2 0.0 0.0082 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EFI27473.1 - 0.0047 16.6 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EFI27473.1 - 0.02 14.5 0.1 0.2 11.2 0.0 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EFI27473.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F-box-like PF12937.2 EFI27474.1 - 2.8e-06 26.9 1.1 2.8e-06 26.9 0.7 2.1 2 0 0 2 2 2 1 F-box-like PadR PF03551.9 EFI27475.1 - 8.8e-06 25.3 0.1 0.11 12.2 0.0 2.1 1 1 0 2 2 2 2 Transcriptional regulator PadR-like family fn1 PF00039.13 EFI27475.1 - 0.005 16.6 0.0 4.1 7.2 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type I domain HTH_29 PF13551.1 EFI27475.1 - 0.014 15.5 0.0 1.9 8.6 0.0 2.0 1 1 1 2 2 2 0 Winged helix-turn helix HTH_28 PF13518.1 EFI27475.1 - 0.016 15.2 0.0 7.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain CENP_C_N PF15622.1 EFI27475.1 - 0.02 14.1 1.1 2.6 7.2 0.1 2.1 1 1 1 2 2 2 0 Kinetochore assembly subunit CENP-C N-terminal Nefa_Nip30_N PF10187.4 EFI27475.1 - 0.023 14.8 1.0 1.4 9.1 0.2 2.1 1 1 1 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 GSIII_N PF12437.3 EFI27475.1 - 0.031 13.6 0.0 6 6.2 0.0 2.1 1 1 1 2 2 2 0 Glutamine synthetase type III N terminal DIL PF01843.14 EFI27475.1 - 0.043 13.7 0.9 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 DIL domain DUF3261 PF11659.3 EFI27475.1 - 0.053 13.1 0.1 3.1 7.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3261) UAE_UbL PF14732.1 EFI27475.1 - 0.06 13.4 0.0 8.6 6.5 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DUF480 PF04337.7 EFI27475.1 - 0.07 12.9 1.0 10 5.9 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function, DUF480 FUR PF01475.14 EFI27475.1 - 0.073 12.9 0.1 13 5.7 0.0 2.1 1 1 1 2 2 2 0 Ferric uptake regulator family Mhr1 PF12829.2 EFI27475.1 - 0.08 12.7 0.3 11 5.8 0.0 2.1 1 1 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination ABC_tran PF00005.22 EFI27478.1 - 7e-16 58.7 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AA_permease_N PF08403.5 EFI27478.1 - 0.099 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal Miro PF08477.8 EFI27479.1 - 0.018 15.5 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein Microvir_lysis PF04517.7 EFI27480.1 - 0.19 11.5 2.1 1.8 8.3 0.6 2.3 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus F-box-like PF12937.2 EFI27483.1 - 0.0001 21.9 0.1 0.65 9.7 0.0 2.6 2 0 0 2 2 2 2 F-box-like Tet_JBP PF12851.2 EFI27488.1 - 6.8e-06 25.4 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HMGL-like PF00682.14 EFI27490.1 - 1.4e-47 162.3 0.0 3.5e-47 161.0 0.0 1.7 1 0 0 1 1 1 1 HMGL-like DnaJ PF00226.26 EFI27490.1 - 1.1e-17 63.4 0.3 8.2e-17 60.7 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain Abhydrolase_6 PF12697.2 EFI27490.1 - 2e-12 47.4 0.0 2.8e-05 24.1 0.0 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EFI27490.1 - 0.0012 18.6 0.0 0.13 12.0 0.0 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Borrelia_P83 PF05262.6 EFI27490.1 - 0.011 14.0 18.1 0.017 13.4 12.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RRN9 PF10680.4 EFI27491.1 - 0.53 10.0 2.8 0.75 9.5 1.9 1.5 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Methyltrn_RNA_4 PF09936.4 EFI27492.1 - 0.053 13.0 1.8 0.12 11.8 1.2 1.6 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Met_asp_mut_E PF06368.6 EFI27496.1 - 0.069 11.3 0.0 0.081 11.0 0.0 1.1 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) NYN PF01936.13 EFI27498.1 - 7.6e-06 26.2 0.0 2.3e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 NYN domain NYN PF01936.13 EFI27499.1 - 3.5e-14 53.2 0.0 6.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 NYN domain Nop14 PF04147.7 EFI27499.1 - 0.0066 14.4 9.9 0.0082 14.1 6.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EFI27499.1 - 0.32 10.2 10.0 0.53 9.5 6.9 1.3 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.11 EFI27499.1 - 1.1 8.2 4.4 1.8 7.4 3.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SPX PF03105.14 EFI27499.1 - 2 8.1 12.3 4.8 6.8 8.5 1.7 1 1 0 1 1 1 0 SPX domain Ebola_NP PF05505.7 EFI27499.1 - 2.6 5.9 9.7 3.6 5.5 6.7 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein SET PF00856.23 EFI27500.1 - 4.2e-26 92.1 0.0 4.2e-26 92.1 0.0 3.7 4 1 0 4 4 4 1 SET domain N-SET PF11764.3 EFI27500.1 - 1.4e-13 51.1 0.2 1.4e-13 51.1 0.1 3.3 2 2 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.17 EFI27500.1 - 1.2e-11 44.0 0.0 3e-09 36.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI27500.1 - 5.8e-07 29.3 0.0 8.3e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EFI27500.1 - 0.0017 18.1 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif NYN PF01936.13 EFI27501.1 - 2.5e-10 40.7 0.0 3.8e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 NYN domain Pkinase PF00069.20 EFI27502.1 - 7.2e-31 107.2 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27502.1 - 3.7e-13 49.1 0.0 1.9e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EFI27502.1 - 0.058 12.4 1.4 0.07 12.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med9 PF07544.8 EFI27502.1 - 2.2 8.0 5.4 13 5.5 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SNF5 PF04855.7 EFI27504.1 - 5.2e-74 248.7 0.8 5.2e-74 248.7 0.6 2.4 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EFI27504.1 - 0.58 9.5 5.7 1.5 8.2 4.0 1.7 1 0 0 1 1 1 0 GATA zinc finger Hid1 PF12722.2 EFI27504.1 - 3.4 5.2 7.3 8.1 3.9 5.0 1.6 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.27 EFI27506.1 - 8.4e-05 22.2 5.0 0.2 11.6 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1834 PF08873.6 EFI27508.1 - 0.076 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) MHYT PF03707.11 EFI27510.1 - 0.6 10.2 0.1 0.6 10.2 0.1 3.7 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Utp12 PF04003.7 EFI27512.1 - 0.12 12.2 0.1 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family BPL_N PF09825.4 EFI27513.1 - 9.8e-18 64.0 0.0 2.2e-10 39.9 0.1 2.7 2 1 0 2 2 2 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EFI27513.1 - 1.2e-11 44.6 0.0 4.8e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family P_C PF06640.6 EFI27515.1 - 0.03 14.3 3.6 0.053 13.5 2.5 1.3 1 0 0 1 1 1 0 P protein C-terminus MaoC_dehydratas PF01575.14 EFI27517.1 - 1.5e-27 95.4 0.0 2.9e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EFI27517.1 - 6.4e-07 29.2 0.0 5.1e-05 23.0 0.0 2.5 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase TauD PF02668.11 EFI27518.1 - 2.3e-56 191.3 0.2 3.2e-56 190.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EFI27518.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 CsiD SNF2_N PF00176.18 EFI27519.1 - 1.2e-74 250.8 0.4 1.7e-74 250.3 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EFI27519.1 - 4.6e-17 61.6 0.0 1.2e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EFI27519.1 - 0.0002 21.2 0.1 0.00049 19.9 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EFI27519.1 - 0.00075 18.4 0.1 0.015 14.0 0.0 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Pterin_bind PF00809.17 EFI27520.1 - 6.1e-45 153.1 0.0 9.2e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EFI27520.1 - 1.4e-32 112.0 0.0 1.5e-28 99.0 0.0 2.4 2 0 0 2 2 2 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EFI27520.1 - 1.4e-16 60.6 0.0 3.3e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Dihydroneopterin aldolase Thaumatin PF00314.12 EFI27520.1 - 1.4e-09 37.7 7.2 2.3e-09 37.0 5.0 1.3 1 0 0 1 1 1 1 Thaumatin family ThiF PF00899.16 EFI27522.1 - 1.3e-36 125.4 0.2 1.9e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 EFI27522.1 - 0.0015 18.7 0.1 0.0038 17.4 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 EFI27522.1 - 0.0028 16.7 0.5 0.012 14.6 0.3 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 EFI27522.1 - 0.016 14.0 0.2 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EFI27522.1 - 0.027 14.1 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTS PF05175.9 EFI27522.1 - 0.063 12.6 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Shikimate_DH PF01488.15 EFI27522.1 - 0.18 11.8 0.9 0.46 10.5 0.2 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EFI27522.1 - 0.22 10.5 0.5 0.35 9.8 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_3 PF01596.12 EFI27523.1 - 3.7e-43 146.9 0.0 4.5e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EFI27523.1 - 4.9e-18 65.9 0.0 7.8e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI27523.1 - 3.9e-12 46.7 0.0 6.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI27523.1 - 7.3e-10 38.6 0.0 9.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EFI27523.1 - 8.6e-08 31.9 0.0 9.9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EFI27523.1 - 3.5e-07 30.2 0.0 7.8e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EFI27523.1 - 0.00023 21.6 0.0 0.0023 18.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EFI27523.1 - 0.00056 19.0 0.0 0.001 18.2 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 EFI27523.1 - 0.00071 19.0 0.0 0.00096 18.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 EFI27523.1 - 0.0029 16.7 0.0 0.0041 16.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.5 EFI27523.1 - 0.026 14.0 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit RseA_C PF03873.8 EFI27524.1 - 7.8 6.4 6.3 33 4.4 4.4 1.9 1 1 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain DUF4200 PF13863.1 EFI27526.1 - 0.003 17.4 0.2 0.005 16.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) IncA PF04156.9 EFI27526.1 - 0.022 14.3 0.1 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EFI27526.1 - 0.04 13.7 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EFI27526.1 - 0.041 12.8 0.1 0.058 12.3 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 EFI27526.1 - 0.043 13.5 0.1 0.07 12.8 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.1 EFI27526.1 - 0.14 11.6 1.0 0.17 11.2 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HrpB7 PF09486.5 EFI27526.1 - 0.19 11.6 3.6 0.34 10.8 1.8 1.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Pox_A_type_inc PF04508.7 EFI27526.1 - 1.9 8.4 4.4 0.53 10.2 0.6 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Gp58 PF07902.6 EFI27528.1 - 0.0076 14.5 0.6 0.011 14.0 0.5 1.1 1 0 0 1 1 1 1 gp58-like protein Cor1 PF04803.7 EFI27528.1 - 0.094 12.4 0.3 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region ApoLp-III PF07464.6 EFI27528.1 - 5 7.1 8.9 11 5.9 5.1 2.2 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) zf-B_box PF00643.19 EFI27530.1 - 3.6 7.5 12.6 1.4 8.8 6.3 2.2 2 0 0 2 2 2 0 B-box zinc finger SET PF00856.23 EFI27533.1 - 2.9e-12 47.1 2.1 5.4e-12 46.3 0.0 2.4 2 2 0 2 2 2 1 SET domain Pheromone PF08015.6 EFI27534.1 - 6.6 7.6 8.4 44 5.0 0.5 4.1 1 1 3 4 4 4 0 Fungal mating-type pheromone BAH PF01426.13 EFI27536.1 - 1.2e-09 37.9 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EFI27536.1 - 0.12 12.0 5.4 0.2 11.4 2.1 2.2 2 0 0 2 2 2 0 PHD-finger CDC45 PF02724.9 EFI27537.1 - 0.69 7.8 9.0 0.94 7.4 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.10 EFI27537.1 - 0.7 9.0 9.5 1.2 8.2 6.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 EFI27537.1 - 9.2 4.5 6.6 13 4.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fungal_trans PF04082.13 EFI27538.1 - 1.6e-06 27.1 0.1 2.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EFI27538.1 - 4.8e-05 23.1 14.0 8e-05 22.4 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC3_N PF07034.6 EFI27540.1 - 1.4e-29 103.1 0.0 5.4e-26 91.3 0.0 2.3 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus MSA-2c PF12238.3 EFI27540.1 - 0.036 13.7 1.1 0.072 12.7 0.8 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c BRO1 PF03097.13 EFI27542.1 - 3.7e-114 381.4 0.2 1.6e-113 379.3 0.0 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EFI27542.1 - 1.1e-58 198.5 8.1 2e-58 197.7 5.6 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Sec2p PF06428.6 EFI27542.1 - 1.7 8.5 11.8 1 9.2 0.1 4.1 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p Epimerase PF01370.16 EFI27543.1 - 2.1e-20 73.1 0.0 2.8e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EFI27543.1 - 5.3e-15 54.8 0.0 9.2e-15 54.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EFI27543.1 - 2e-14 54.0 0.0 4.6e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EFI27543.1 - 6.2e-08 31.8 0.0 1.5e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EFI27543.1 - 5.6e-06 25.7 0.0 7.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EFI27543.1 - 0.0002 21.2 0.0 0.00088 19.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EFI27543.1 - 0.0032 17.1 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EFI27543.1 - 0.023 13.5 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Trs65 PF12735.2 EFI27544.1 - 9.6e-30 103.9 6.0 5.6e-27 94.8 0.0 3.5 3 0 0 3 3 3 2 TRAPP trafficking subunit Trs65 GFA PF04828.9 EFI27548.1 - 1.2e-21 76.3 0.3 2e-21 75.7 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ank_5 PF13857.1 EFI27550.1 - 1.8e-07 31.1 0.0 2.8e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EFI27550.1 - 9.2e-06 25.9 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EFI27550.1 - 2.8e-05 24.5 0.0 0.045 14.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EFI27550.1 - 0.00014 21.5 0.0 0.00058 19.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.20 EFI27551.1 - 4.2e-07 29.3 0.0 7.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27551.1 - 0.00082 18.5 0.1 0.0023 17.0 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EFI27553.1 - 6.6e-09 35.2 0.1 6e-08 32.1 0.1 2.0 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27553.1 - 7.3e-06 25.2 0.2 1.7e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EFI27554.1 - 3e-12 46.2 0.0 8.7e-12 44.7 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27554.1 - 3.4e-05 23.0 0.0 5.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4219 PF13961.1 EFI27554.1 - 0.11 11.9 0.1 0.34 10.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Pkinase PF00069.20 EFI27555.1 - 8.1e-11 41.5 0.0 2.8e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27555.1 - 6e-06 25.5 0.1 1.2e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EFI27556.1 - 2.6e-63 213.6 0.0 3.9e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27556.1 - 1.8e-46 158.3 0.0 3.2e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 EFI27556.1 - 2e-16 59.9 0.0 3.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 EFI27556.1 - 1.5e-05 24.1 0.0 3.2e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EFI27556.1 - 0.00047 19.9 2.3 0.0092 15.7 0.1 3.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Glyco_transf_90 PF05686.7 EFI27557.1 - 1.5e-14 53.5 0.4 2.7e-12 46.1 0.2 3.4 3 1 0 3 3 3 1 Glycosyl transferase family 90 Tetraspannin PF00335.15 EFI27557.1 - 0.12 11.5 1.3 0.29 10.3 0.5 1.9 2 0 0 2 2 2 0 Tetraspanin family RasGEF PF00617.14 EFI27560.1 - 2e-06 27.6 0.5 2.6e-06 27.3 0.1 1.5 2 0 0 2 2 2 1 RasGEF domain F-box-like PF12937.2 EFI27561.1 - 0.019 14.7 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 F-box-like adh_short PF00106.20 EFI27564.1 - 3.6e-28 98.5 0.1 5.3e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EFI27564.1 - 3.9e-28 98.8 0.3 5.5e-28 98.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EFI27564.1 - 8.9e-15 54.8 0.0 1.8e-14 53.8 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EFI27564.1 - 0.0053 16.2 0.2 0.0075 15.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EFI27564.1 - 0.011 14.7 0.3 0.091 11.7 0.1 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EFI27564.1 - 0.1 12.2 0.0 1.2 8.7 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GHMP_kinases_C PF08544.8 EFI27564.1 - 0.13 12.4 0.1 0.4 10.8 0.1 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal DUF3235 PF11574.3 EFI27564.1 - 0.3 11.3 1.9 4 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) zf-CCHC PF00098.18 EFI27569.1 - 0.0024 17.7 0.9 0.0035 17.1 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle NADH_u_ox_C PF12853.2 EFI27570.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit ABC2_membrane PF01061.19 EFI27571.1 - 3e-72 242.1 57.3 1.1e-40 139.0 12.0 2.4 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EFI27571.1 - 3.9e-29 100.3 0.0 1.1e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.22 EFI27571.1 - 4.8e-29 101.4 0.0 5.2e-17 62.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EFI27571.1 - 2e-06 27.0 19.8 2e-06 27.0 13.7 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EFI27571.1 - 4.1e-06 26.0 0.0 4.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EFI27571.1 - 0.00032 21.0 0.0 0.093 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EFI27571.1 - 0.00046 19.6 0.0 0.0028 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EFI27571.1 - 0.00057 20.6 0.0 0.24 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EFI27571.1 - 0.0031 17.6 0.0 0.02 15.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EFI27571.1 - 0.0068 15.8 0.4 0.016 14.6 0.1 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EFI27571.1 - 0.01 15.8 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 EFI27571.1 - 0.011 15.7 0.0 0.76 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EFI27571.1 - 0.018 14.5 0.1 0.052 13.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EFI27571.1 - 0.033 14.0 0.1 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EFI27571.1 - 0.091 12.4 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 EFI27571.1 - 0.16 11.5 0.2 0.43 10.2 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EFI27571.1 - 0.2 11.5 1.1 5.3 7.0 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EFI27571.1 - 0.62 9.0 0.0 1 8.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 EFI27577.1 - 0.0001 21.5 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ABC_membrane PF00664.18 EFI27578.1 - 7.7e-28 97.6 6.7 1.1e-27 97.1 4.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EFI27578.1 - 4e-27 95.1 0.0 7.9e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EFI27578.1 - 4.7e-06 26.7 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EFI27578.1 - 0.00072 20.3 0.0 0.0021 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EFI27578.1 - 0.0012 18.8 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EFI27578.1 - 0.0013 18.8 0.2 0.013 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EFI27578.1 - 0.0021 17.8 0.0 0.01 15.5 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EFI27578.1 - 0.0022 17.8 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EFI27578.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EFI27578.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EFI27578.1 - 0.043 13.0 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EFI27578.1 - 0.085 12.2 0.0 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EFI27578.1 - 0.11 11.1 0.0 0.24 10.0 0.0 1.4 2 0 0 2 2 2 0 G-protein alpha subunit PBP1_TM PF14812.1 EFI27578.1 - 3.6 7.9 10.9 6.8 7.0 4.1 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_membrane PF00664.18 EFI27579.1 - 4.1e-40 137.9 6.3 1.2e-39 136.3 4.4 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EFI27579.1 - 9.5e-10 38.9 0.1 1e-05 25.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_17 PF13207.1 EFI27579.1 - 0.00067 20.4 0.0 0.0015 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EFI27579.1 - 0.0048 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EFI27579.1 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EFI27579.1 - 0.025 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EFI27579.1 - 0.027 13.8 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EFI27579.1 - 0.031 14.5 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EFI27579.1 - 0.034 14.2 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EFI27579.1 - 0.039 13.9 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 EFI27579.1 - 0.12 11.8 0.0 0.86 9.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EFI27579.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EFI27579.1 - 0.16 11.3 0.2 0.28 10.5 0.2 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EFI27579.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EFI27582.1 - 8.3e-06 25.1 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EFI27583.1 - 0.00017 20.8 0.0 0.00034 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PEARLI-4 PF05278.7 EFI27585.1 - 0.0044 16.4 0.5 0.0062 15.9 0.3 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF641 PF04859.7 EFI27585.1 - 0.024 14.3 1.1 0.035 13.8 0.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ADIP PF11559.3 EFI27585.1 - 0.025 14.4 1.7 0.033 14.1 1.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.6 EFI27585.1 - 0.03 14.1 2.9 0.042 13.6 2.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.4 EFI27585.1 - 0.075 13.0 0.7 0.11 12.5 0.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_DNA_bd PF12329.3 EFI27585.1 - 0.097 12.4 3.1 0.14 11.9 0.6 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Prok-E2_D PF14460.1 EFI27587.1 - 0.023 14.1 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family D APG17 PF04108.7 EFI27589.1 - 0.0051 15.6 0.1 0.0061 15.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 MEA1 PF06910.6 EFI27589.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) THOC7 PF05615.8 EFI27589.1 - 0.056 13.7 0.2 0.063 13.5 0.1 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 DUF2457 PF10446.4 EFI27591.1 - 0.63 8.7 9.7 0.69 8.5 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tet_JBP PF12851.2 EFI27592.1 - 5.2e-17 61.6 0.0 8.3e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Tet_JBP PF12851.2 EFI27593.1 - 1.2e-16 60.4 0.0 1.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DLH PF01738.13 EFI27598.1 - 3.8e-15 55.7 0.0 5.3e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EFI27598.1 - 4.5e-06 26.4 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EFI27598.1 - 0.029 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GRA6 PF05084.8 EFI27600.1 - 0.027 13.9 0.4 0.068 12.6 0.0 1.8 2 0 0 2 2 2 0 Granule antigen protein (GRA6) Na_Ca_ex PF01699.19 EFI27600.1 - 0.092 12.3 12.2 4.5 6.8 0.2 3.7 3 1 0 3 3 3 0 Sodium/calcium exchanger protein TctB PF07331.6 EFI27600.1 - 0.17 11.5 14.3 22 4.6 0.1 3.9 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family TFIIA PF03153.8 EFI27601.1 - 0.0025 17.7 7.9 0.0025 17.7 5.5 3.3 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF1399 PF07173.7 EFI27606.1 - 4.3e-15 56.1 0.0 1.8e-14 54.1 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1399) F-box-like PF12937.2 EFI27607.1 - 3.6e-05 23.3 0.4 3.6e-05 23.3 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EFI27607.1 - 0.022 14.4 1.8 0.053 13.1 0.4 2.4 2 0 0 2 2 2 0 F-box domain SH3_9 PF14604.1 EFI27612.1 - 0.0039 16.7 0.1 0.34 10.5 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain Nop14 PF04147.7 EFI27612.1 - 0.022 12.7 0.2 0.034 12.0 0.2 1.2 1 0 0 1 1 1 0 Nop14-like family SH3_2 PF07653.12 EFI27612.1 - 0.026 14.0 2.1 0.32 10.5 0.1 2.9 3 0 0 3 3 3 0 Variant SH3 domain UB2H PF14814.1 EFI27612.1 - 0.089 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain OTT_1508_deam PF14441.1 EFI27613.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase UPF0154 PF03672.8 EFI27615.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) MEDS PF14417.1 EFI27615.1 - 0.044 12.8 0.1 0.08 11.9 0.1 1.5 1 1 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Abhydrolase_1 PF00561.15 EFI27616.1 - 1.5e-15 57.4 0.0 1.3e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EFI27616.1 - 8.8e-13 48.0 0.0 2.7e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EFI27616.1 - 4.9e-07 29.8 0.4 1e-06 28.8 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EFI27617.1 - 1.1e-32 113.2 0.3 1e-30 106.7 0.4 2.8 2 1 0 2 2 2 2 Cytochrome P450 Helicase_C PF00271.26 EFI27619.1 - 2e-09 37.1 0.0 8.8e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EFI27619.1 - 2.7e-09 36.7 0.0 5.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_4 PF12799.2 EFI27620.1 - 1.5e-28 97.9 25.6 1e-09 37.7 0.9 9.1 6 2 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EFI27620.1 - 7.6e-20 68.7 12.2 0.97 9.7 0.1 10.8 11 0 0 11 11 11 7 Leucine Rich repeat LRR_1 PF00560.28 EFI27620.1 - 1.8e-19 66.7 22.1 0.065 13.2 0.0 10.7 10 1 1 11 11 11 7 Leucine Rich Repeat LRR_7 PF13504.1 EFI27620.1 - 7.8e-16 55.4 16.2 0.39 11.1 0.1 10.6 11 1 1 12 12 12 6 Leucine rich repeat LRR_8 PF13855.1 EFI27620.1 - 3.4e-15 55.5 20.4 6.1e-07 29.0 1.1 8.3 6 2 1 8 8 8 6 Leucine rich repeat Ank PF00023.25 EFI27622.1 - 0.0003 20.4 0.4 0.0011 18.7 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EFI27622.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EFI27622.1 - 0.032 14.7 0.1 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPR_12 PF13424.1 EFI27623.1 - 6.4e-26 90.1 12.1 0.0051 16.7 0.3 12.5 4 3 10 14 14 14 10 Tetratricopeptide repeat CHAT PF12770.2 EFI27623.1 - 6.6e-22 77.9 0.0 1.3e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EFI27623.1 - 2.3e-15 55.9 7.5 0.0066 16.0 0.0 9.0 5 4 5 11 11 11 3 TPR repeat TPR_17 PF13431.1 EFI27623.1 - 4.5e-11 42.0 3.7 1.1 9.6 0.0 9.7 10 0 0 10 10 9 1 Tetratricopeptide repeat Ank_2 PF12796.2 EFI27623.1 - 6.2e-10 39.2 0.3 2.8e-06 27.5 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EFI27623.1 - 1.1e-09 38.5 0.1 7.4e-06 26.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) TPR_10 PF13374.1 EFI27623.1 - 6.9e-07 28.9 33.4 0.28 11.1 0.3 12.1 15 0 0 15 15 15 3 Tetratricopeptide repeat Ank PF00023.25 EFI27623.1 - 7.5e-07 28.6 0.7 0.015 15.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EFI27623.1 - 5.1e-05 23.3 1.1 0.057 13.6 0.0 3.6 4 0 0 4 4 3 1 Ankyrin repeats (many copies) TPR_1 PF00515.23 EFI27623.1 - 5.7e-05 22.5 4.1 63 3.4 0.0 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat Ank_3 PF13606.1 EFI27623.1 - 0.00061 19.7 0.1 3.3 8.2 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat TPR_2 PF07719.12 EFI27623.1 - 0.0063 16.3 5.5 56 4.0 0.0 7.4 10 0 0 10 10 6 0 Tetratricopeptide repeat RuvB_C PF05491.8 EFI27623.1 - 0.039 13.5 0.0 1.6 8.3 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB C-terminus Complex1_LYR PF05347.10 EFI27623.1 - 0.064 13.0 0.0 0.68 9.7 0.0 2.9 2 0 0 2 2 2 0 Complex 1 protein (LYR family) LRS4 PF10422.4 EFI27625.1 - 0.14 11.4 1.7 0.2 10.9 1.2 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF1431 PF07248.7 EFI27625.1 - 0.52 10.2 6.9 0.19 11.6 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1431) Transferase PF02458.10 EFI27626.1 - 0.00012 20.6 0.0 0.0031 16.0 0.0 2.6 2 1 0 2 2 2 1 Transferase family MIS13 PF08202.6 EFI27627.1 - 0.081 11.9 0.1 0.085 11.9 0.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family F-box PF00646.28 EFI27628.1 - 7.9e-05 22.2 0.2 0.00021 20.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EFI27628.1 - 0.0001 21.9 0.1 0.00025 20.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like Cyclin PF08613.6 EFI27629.1 - 6e-35 120.8 4.1 1.7e-23 83.6 0.0 4.2 5 1 0 5 5 5 2 Cyclin DUF2454 PF10521.4 EFI27638.1 - 3.3e-22 78.8 0.0 6.4e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) DUF2414 PF10309.4 EFI27639.1 - 3.9e-06 26.4 0.0 6.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 EFI27639.1 - 0.006 17.0 9.6 0.006 17.0 6.6 4.2 4 1 0 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 dCMP_cyt_deam_1 PF00383.17 EFI27640.1 - 8.3e-22 76.7 0.2 1.2e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EFI27640.1 - 0.0019 17.8 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 EFI27640.1 - 0.0029 17.4 1.2 0.028 14.2 0.9 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase AA_permease_2 PF13520.1 EFI27643.1 - 1.1e-46 159.2 53.4 1.4e-46 158.8 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EFI27643.1 - 2.2e-25 88.9 45.0 2.8e-25 88.6 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease PGM_PMM_III PF02880.11 EFI27643.1 - 0.051 13.6 0.4 0.58 10.2 0.1 2.3 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III GTP_EFTU PF00009.22 EFI27644.1 - 3.4e-32 111.4 0.0 1.5e-31 109.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EFI27644.1 - 1.4e-18 66.7 0.0 3.5e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EFI27644.1 - 2.3e-14 53.2 4.7 6.7e-10 38.9 0.0 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EFI27644.1 - 2.1e-07 30.9 0.0 5.6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EFI27644.1 - 0.0073 16.4 0.1 0.025 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EFI27644.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ras PF00071.17 EFI27644.1 - 0.017 14.5 0.1 0.081 12.3 0.0 2.2 1 1 0 1 1 1 0 Ras family Arf PF00025.16 EFI27645.1 - 1.5e-66 222.9 0.1 5.8e-65 217.7 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EFI27645.1 - 1.5e-12 46.9 0.8 1.8e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EFI27645.1 - 1.4e-09 37.4 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EFI27645.1 - 1.8e-07 31.1 0.0 3.7e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EFI27645.1 - 2.2e-07 30.4 0.0 2.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EFI27645.1 - 8.7e-07 28.3 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EFI27645.1 - 1.2e-06 28.9 0.0 1.9e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EFI27645.1 - 0.00016 21.1 0.0 0.0011 18.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EFI27645.1 - 0.0035 16.8 0.0 0.045 13.2 0.0 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EFI27645.1 - 0.079 12.6 0.2 0.36 10.4 0.1 1.9 1 1 0 1 1 1 0 NACHT domain RAMP PF04901.8 EFI27649.1 - 0.074 12.8 0.7 0.12 12.1 0.5 1.3 1 0 0 1 1 1 0 Receptor activity modifying family zf-NPL4 PF05020.10 EFI27649.1 - 0.26 10.9 3.2 0.38 10.3 2.2 1.2 1 0 0 1 1 1 0 NPL4 family, putative zinc binding region Cyclin_N PF00134.18 EFI27651.1 - 0.033 13.7 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF2618 PF10940.3 EFI27651.1 - 0.089 12.5 0.4 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) GAS2 PF02187.12 EFI27652.1 - 2e-08 33.8 0.1 4.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain EzrA PF06160.7 EFI27653.1 - 0.015 13.4 1.7 0.02 13.1 1.2 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DivIVA PF05103.8 EFI27653.1 - 0.47 10.5 6.4 0.15 12.1 2.2 1.8 2 1 0 2 2 2 0 DivIVA protein NUDE_C PF04880.8 EFI27653.1 - 1.2 9.5 5.3 0.86 9.9 0.7 2.3 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region GrpE PF01025.14 EFI27653.1 - 1.3 8.5 6.7 2.3 7.7 2.4 2.1 1 1 1 2 2 2 0 GrpE APG6 PF04111.7 EFI27653.1 - 2.8 6.9 6.0 5.4 5.9 4.2 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 EFI27653.1 - 3.2 7.5 9.2 1.6 8.4 4.8 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 EFI27653.1 - 4.9 7.5 9.8 0.52 10.6 2.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF904) ThiF PF00899.16 EFI27654.1 - 3.5e-50 169.3 0.0 1.5e-28 99.2 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EFI27654.1 - 1.2e-46 157.8 0.6 2.6e-46 156.8 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EFI27654.1 - 8.3e-42 140.6 1.9 7.8e-28 95.8 0.1 3.8 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EFI27654.1 - 5.5e-23 80.0 0.6 3.4e-19 67.9 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Aminotran_3 PF00202.16 EFI27655.1 - 3.4e-92 308.9 0.0 4.4e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EFI27655.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EFI27655.1 - 0.049 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Alpha_kinase PF02816.13 EFI27656.1 - 0.0006 19.5 0.0 0.00078 19.1 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family MT-A70 PF05063.9 EFI27657.1 - 1.5e-54 184.2 0.1 3e-54 183.2 0.0 1.5 1 1 0 1 1 1 1 MT-A70 RRM_1 PF00076.17 EFI27660.1 - 8.5e-18 63.7 0.0 1.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI27660.1 - 4.8e-16 58.5 0.0 1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI27660.1 - 2.4e-08 33.7 0.0 4.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.15 EFI27661.1 - 3.8e-20 71.7 0.0 5.5e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Tau95 PF09734.4 EFI27662.1 - 8.9e-66 222.3 1.0 1.9e-65 221.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit EAF PF09816.4 EFI27662.1 - 0.052 13.5 0.1 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription elongation factor Ribosomal_L29e PF01779.12 EFI27663.1 - 3.4e-23 81.2 12.6 4.4e-23 80.8 8.7 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family DUF4451 PF14616.1 EFI27664.1 - 1.1e-31 109.1 1.7 1.7e-31 108.5 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Vfa1 PF08432.5 EFI27665.1 - 7.9e-38 130.2 8.4 9.5e-38 130.0 5.8 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 EFI27665.1 - 0.0075 15.6 7.4 0.0095 15.3 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4407 PF14362.1 EFI27665.1 - 0.081 11.8 0.7 0.084 11.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.3 EFI27665.1 - 0.11 11.2 9.5 0.14 10.8 6.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pex14_N PF04695.8 EFI27665.1 - 0.21 11.6 6.0 0.34 10.9 4.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3987 PF13148.1 EFI27665.1 - 0.27 9.7 11.2 0.45 9.0 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ycf1 PF05758.7 EFI27665.1 - 0.32 8.6 3.5 0.32 8.6 2.4 1.0 1 0 0 1 1 1 0 Ycf1 Packaging_FI PF14000.1 EFI27665.1 - 0.37 10.9 6.2 0.57 10.3 4.3 1.2 1 0 0 1 1 1 0 DNA packaging protein FI APC_CDC26 PF10471.4 EFI27665.1 - 0.53 11.0 8.2 1.4 9.6 4.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Pox_Ag35 PF03286.9 EFI27665.1 - 0.85 9.1 12.1 1.2 8.5 8.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein U79_P34 PF03064.11 EFI27665.1 - 1 8.8 8.5 1.2 8.5 5.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Hid1 PF12722.2 EFI27665.1 - 1.7 6.2 6.6 1.9 6.0 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 EFI27665.1 - 2.6 7.8 12.0 3.1 7.6 8.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.9 EFI27665.1 - 2.8 7.2 6.2 4.2 6.6 4.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Uds1 PF15456.1 EFI27665.1 - 2.9 7.8 10.6 4.4 7.3 7.3 1.3 1 1 0 1 1 1 0 Up-regulated During Septation DUF3513 PF12026.3 EFI27665.1 - 3.4 7.1 8.0 4.7 6.6 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) FancD2 PF14631.1 EFI27665.1 - 3.4 4.6 4.8 4.3 4.2 3.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CDC45 PF02724.9 EFI27665.1 - 3.8 5.4 8.5 4.4 5.2 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.6 EFI27665.1 - 4.3 5.5 11.9 4.9 5.2 8.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Proteasome PF00227.21 EFI27666.1 - 8.8e-54 181.6 0.0 1.2e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EFI27666.1 - 2.8e-12 45.7 0.0 2.8e-12 45.7 0.0 2.2 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature GTP_EFTU PF00009.22 EFI27667.1 - 2.2e-33 115.2 0.0 3.1e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EFI27667.1 - 7.1e-10 38.9 0.0 2.9e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EFI27667.1 - 2.5e-07 30.6 0.1 4.7e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EFI27667.1 - 5.3e-06 25.9 0.0 1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EFI27667.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EFI27667.1 - 0.13 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HBS1_N PF08938.5 EFI27668.1 - 3.4e-09 36.7 0.5 7.6e-09 35.5 0.4 1.6 1 0 0 1 1 1 1 HBS1 N-terminus Arf PF00025.16 EFI27668.1 - 0.21 10.8 0.6 0.35 10.0 0.4 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family SSB PF00436.20 EFI27669.1 - 1.9e-17 62.9 0.0 2.6e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.20 EFI27669.1 - 0.046 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNB PF00773.14 EFI27670.1 - 1.5e-91 307.0 0.0 2.1e-91 306.6 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EFI27670.1 - 3.6e-06 27.1 0.0 9.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 EFI27670.1 - 0.0087 15.5 2.1 0.015 14.7 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain DSPc PF00782.15 EFI27671.1 - 3.4e-30 104.3 0.0 4.3e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EFI27671.1 - 0.00037 19.9 0.1 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EFI27671.1 - 0.089 11.6 0.0 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase OppC_N PF12911.2 EFI27673.1 - 0.082 12.2 0.2 0.082 12.2 0.1 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C BBP1_C PF15272.1 EFI27674.1 - 1.4 8.4 17.0 0.062 12.8 4.8 2.3 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal RNA_pol_Rpb1_5 PF04998.12 EFI27675.1 - 2.2e-88 296.1 0.0 5.5e-88 294.8 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EFI27675.1 - 5.2e-51 172.8 0.1 1.1e-50 171.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EFI27675.1 - 8.6e-38 129.5 0.0 2.1e-37 128.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EFI27675.1 - 1.1e-28 100.4 9.3 3.9e-24 85.5 0.0 3.8 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EFI27675.1 - 9.6e-21 73.5 0.0 2.6e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Lactamase_B_2 PF12706.2 EFI27678.1 - 6.1e-21 74.8 0.0 9.8e-21 74.1 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EFI27678.1 - 7.8e-09 35.4 0.0 2e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EFI27678.1 - 5.8e-06 25.6 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.10 EFI27678.1 - 0.019 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Pex14_N PF04695.8 EFI27679.1 - 7.4e-10 39.0 8.7 6.8e-09 35.8 0.0 2.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 EFI27681.1 - 3.3e-64 216.5 0.0 2.2e-41 141.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27681.1 - 7.5e-28 97.3 0.0 5.7e-23 81.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EFI27681.1 - 7.2e-13 48.5 0.0 1.3e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EFI27681.1 - 5.5e-07 28.8 0.1 0.00014 20.9 0.0 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EFI27681.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EFI27681.1 - 0.018 14.1 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EFI27681.1 - 0.02 14.2 0.1 0.048 13.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EFI27681.1 - 0.062 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 VMA21 PF09446.5 EFI27682.1 - 6.6e-06 25.9 1.6 7.5e-06 25.7 1.1 1.1 1 0 0 1 1 1 1 VMA21-like domain TGS PF02824.16 EFI27683.1 - 5.6e-24 83.7 0.1 1e-23 82.9 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EFI27683.1 - 2.6e-17 62.8 0.0 5.5e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EFI27683.1 - 3.5e-08 32.8 0.2 1e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EFI27683.1 - 0.0048 16.7 0.3 2 8.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EFI27683.1 - 0.0065 15.2 0.7 0.018 13.8 0.1 1.9 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 EFI27683.1 - 0.039 13.4 0.3 10 5.5 0.1 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EFI27683.1 - 0.16 11.1 0.8 4.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATE_C PF04377.10 EFI27684.1 - 7.6e-41 139.1 0.4 2.1e-40 137.7 0.3 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus Brix PF04427.13 EFI27685.1 - 8.8e-42 142.9 0.3 1.2e-41 142.5 0.2 1.2 1 0 0 1 1 1 1 Brix domain Cys_Met_Meta_PP PF01053.15 EFI27686.1 - 4.5e-60 202.9 0.0 8.3e-60 202.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RRM_6 PF14259.1 EFI27687.1 - 1.3e-15 57.1 0.0 5.2e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EFI27687.1 - 3.2e-15 55.4 0.0 6.3e-08 32.1 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI27687.1 - 8.9e-12 44.6 0.0 2.7e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AhpC-TSA PF00578.16 EFI27688.1 - 7.9e-34 116.0 0.0 1e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EFI27688.1 - 5.6e-13 48.6 0.0 7.4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EFI27688.1 - 1.2e-10 40.8 0.0 2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PS_Dcarbxylase PF02666.10 EFI27688.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase Proteasome PF00227.21 EFI27689.1 - 4.6e-29 101.0 0.1 1.8e-24 86.1 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit Aldedh PF00171.17 EFI27690.1 - 5.3e-157 522.8 1.8 3.8e-77 259.5 0.0 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family Thiolase_N PF00108.18 EFI27691.1 - 2.3e-89 298.8 0.2 3.4e-89 298.3 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EFI27691.1 - 1.2e-38 131.2 0.9 3e-38 129.9 0.6 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain Autophagy_act_C PF03987.10 EFI27691.1 - 5.4e-08 32.8 0.1 1.6e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain ketoacyl-synt PF00109.21 EFI27691.1 - 0.00019 20.9 0.5 0.0005 19.6 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF1640 PF07798.6 EFI27692.1 - 5.8e-15 55.7 4.8 7.7e-15 55.3 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GST_N PF02798.15 EFI27692.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EFI27692.1 - 5.7e-06 26.4 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EFI27692.1 - 2.2e-05 24.3 0.0 5.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lipoprotein_7 PF01540.11 EFI27692.1 - 0.0053 15.8 1.6 0.0073 15.4 1.1 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein BNIP2 PF12496.3 EFI27692.1 - 0.12 12.4 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Fzo_mitofusin PF04799.8 EFI27692.1 - 0.64 9.3 4.4 1 8.7 2.2 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF1843 PF08898.5 EFI27692.1 - 1.3 9.0 7.3 9.4 6.3 0.1 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF1843) DUF1451 PF07295.6 EFI27692.1 - 1.6 8.4 4.5 2.5 7.8 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DEAD PF00270.24 EFI27693.1 - 8e-15 54.7 0.0 1.7e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EFI27693.1 - 8.6e-08 31.9 0.0 2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 EFI27693.1 - 0.00013 21.4 0.1 0.043 13.4 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI27693.1 - 0.00021 21.2 0.0 0.00062 19.6 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI27693.1 - 0.069 13.0 0.1 0.69 9.8 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gastrin PF00918.12 EFI27693.1 - 0.4 11.5 1.3 1.2 9.9 0.9 1.8 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Sua5_yciO_yrdC PF01300.13 EFI27694.1 - 2e-53 180.2 0.0 4.2e-53 179.2 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EFI27694.1 - 5.9e-28 97.4 0.0 3e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding Complex1_LYR_2 PF13233.1 EFI27694.1 - 1.4e-09 38.3 0.2 2.7e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EFI27694.1 - 0.013 15.7 0.7 0.03 14.5 0.5 1.6 1 0 0 1 1 1 0 Complex1_LYR-like MFS_1 PF07690.11 EFI27695.1 - 6.3e-40 136.9 26.5 7.7e-40 136.6 18.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TraU PF06834.6 EFI27696.1 - 0.02 14.0 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 TraU protein Sedlin_N PF04628.8 EFI27697.1 - 1.7e-27 95.9 0.1 2e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Mito_carr PF00153.22 EFI27698.1 - 1.1e-51 172.5 10.5 1.2e-18 66.5 0.4 3.5 3 1 1 4 4 4 3 Mitochondrial carrier protein Repressor_Mnt PF11423.3 EFI27698.1 - 0.038 13.2 0.0 8.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Regulatory protein Mnt FF PF01846.14 EFI27699.1 - 3.3e-42 142.2 17.1 7.6e-13 48.1 0.0 6.7 6 0 0 6 6 6 6 FF domain WW PF00397.21 EFI27699.1 - 1e-12 47.6 5.7 2.8e-06 27.0 0.9 2.9 2 0 0 2 2 2 2 WW domain HSP90 PF00183.13 EFI27700.1 - 1.8e-122 409.4 7.3 2.2e-122 409.1 5.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EFI27700.1 - 2.2e-08 33.8 1.1 3.9e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EFI27700.1 - 1.1e-05 25.1 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Yos1 PF08571.5 EFI27701.1 - 3.7e-19 68.6 0.0 5.5e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Yos1-like TFIIF_alpha PF05793.7 EFI27702.1 - 1.7e-11 43.1 32.5 0.00018 20.0 16.4 3.4 3 0 0 3 3 3 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.10 EFI27702.1 - 0.074 12.3 8.3 0.14 11.4 5.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HLH PF00010.21 EFI27703.1 - 4.1e-16 58.4 0.6 8.1e-16 57.4 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NYD-SP28_assoc PF14775.1 EFI27703.1 - 0.021 14.4 0.3 0.039 13.6 0.2 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4106 PF13388.1 EFI27703.1 - 0.066 12.1 1.4 0.11 11.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CAF-1_p150 PF11600.3 EFI27703.1 - 4 6.7 10.7 6.1 6.1 7.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cupin_8 PF13621.1 EFI27704.1 - 2.7e-53 181.0 0.0 4.7e-53 180.2 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EFI27704.1 - 0.0043 17.2 0.0 0.045 14.0 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EFI27704.1 - 0.019 14.2 0.0 0.049 12.8 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_2 PF07883.6 EFI27704.1 - 0.091 12.2 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Cupin domain UPF0184 PF03670.8 EFI27706.1 - 0.28 11.3 16.2 0.088 12.9 0.5 4.2 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0184) NPV_P10 PF05531.7 EFI27706.1 - 1.6 9.0 14.5 2.7 8.2 0.5 4.3 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF3818 PF12825.2 EFI27707.1 - 9.4e-112 373.0 0.0 1.3e-111 372.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EFI27707.1 - 3.1e-29 101.3 0.1 8.5e-29 99.9 0.1 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EFI27707.1 - 8.5e-10 38.4 0.2 6.3e-09 35.6 0.0 2.6 2 0 0 2 2 2 1 PX domain RNB PF00773.14 EFI27707.1 - 0.0021 17.4 0.1 0.0051 16.1 0.0 1.6 2 0 0 2 2 2 1 RNB domain Zip PF02535.17 EFI27707.1 - 2.3 7.1 9.0 4 6.3 6.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter LON PF02190.11 EFI27708.1 - 8.1e-11 41.9 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EFI27708.1 - 6.1e-07 29.3 30.4 0.0012 18.8 9.7 3.3 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EFI27708.1 - 1.4e-06 28.0 25.9 2.9e-05 23.8 3.1 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EFI27708.1 - 6.4e-06 25.7 27.6 0.0028 17.3 9.6 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EFI27708.1 - 0.0018 17.9 29.8 0.048 13.3 10.3 3.1 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EFI27708.1 - 0.0042 16.8 16.1 0.0042 16.8 11.1 3.0 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EFI27708.1 - 0.0061 16.2 32.4 0.39 10.4 5.6 3.1 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_6 PF14835.1 EFI27708.1 - 0.13 12.1 12.3 1.3 8.8 2.6 2.8 3 0 0 3 3 3 0 zf-RING of BARD1-type protein ORC6 PF05460.8 EFI27708.1 - 0.21 10.6 4.1 0.074 12.1 0.2 1.8 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF35_N PF12172.3 EFI27708.1 - 0.31 11.0 0.0 0.31 11.0 0.0 3.2 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-RING_4 PF14570.1 EFI27708.1 - 1.8 8.2 12.2 0.057 13.0 1.2 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain PG_binding_1 PF01471.13 EFI27709.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain WD40 PF00400.27 EFI27711.1 - 1.6e-26 91.1 3.3 2.9e-09 36.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat SDA1 PF05285.7 EFI27711.1 - 0.15 11.3 6.3 0.22 10.7 4.4 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.7 EFI27711.1 - 1.1 8.9 10.7 1.7 8.2 7.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EFI27711.1 - 1.5 6.7 5.5 2.2 6.2 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EFI27711.1 - 4.6 6.7 9.1 8.4 5.9 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EFI27711.1 - 7 5.0 12.6 9.8 4.5 8.7 1.1 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 EFI27713.1 - 3e-75 252.7 0.0 3.8e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27713.1 - 8.3e-39 133.2 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI27713.1 - 3.7e-07 29.4 0.0 5.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EFI27713.1 - 0.028 13.4 0.1 0.062 12.3 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bromodomain PF00439.20 EFI27714.1 - 9.6e-23 79.9 0.0 1.8e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF3336 PF11815.3 EFI27715.1 - 6.9e-44 148.8 1.7 1.2e-43 148.1 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EFI27715.1 - 1.6e-20 73.8 0.1 3e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Borrelia_P83 PF05262.6 EFI27716.1 - 0.082 11.1 2.2 0.11 10.7 1.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein WH2 PF02205.15 EFI27717.1 - 2.6e-09 36.3 1.5 7.8e-09 34.8 0.5 2.1 2 0 0 2 2 2 1 WH2 motif Gln-synt_C PF00120.19 EFI27718.1 - 2e-62 210.6 0.0 2.4e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EFI27718.1 - 2.6e-18 65.3 0.0 4.5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF2036 PF09724.4 EFI27719.1 - 7.5e-57 192.9 0.1 8.8e-57 192.6 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RNase_P_Rpp14 PF01900.14 EFI27719.1 - 0.024 14.5 0.0 0.14 12.0 0.0 2.1 1 1 1 2 2 2 0 Rpp14/Pop5 family DUF721 PF05258.7 EFI27719.1 - 0.1 12.8 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF721) Mito_carr PF00153.22 EFI27720.1 - 8.1e-65 214.5 2.3 3.4e-22 77.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EFI27720.1 - 7.1e-05 22.8 3.4 7.1e-05 22.8 2.4 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EFI27720.1 - 0.00052 19.1 1.4 0.0019 17.3 0.4 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EFI27720.1 - 0.00073 18.7 1.1 0.00073 18.7 0.8 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EFI27720.1 - 0.0032 17.2 1.6 0.015 15.1 0.9 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EFI27720.1 - 0.091 12.3 0.8 1.4 8.5 0.4 3.1 3 1 0 3 3 3 0 EF-hand domain pair Apt1 PF10351.4 EFI27721.1 - 1.6e-66 225.0 0.0 2.9e-66 224.2 0.0 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EFI27721.1 - 3.6e-61 207.0 0.0 8.7e-61 205.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EFI27721.1 - 1.2e-39 135.7 0.1 2.3e-39 134.8 0.1 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EFI27721.1 - 1.6e-24 86.4 0.0 1e-23 83.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EFI27721.1 - 2.3e-13 50.4 0.0 6.4e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain PIN_4 PF13638.1 EFI27722.1 - 8.7e-22 77.6 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 PIN domain PIN PF01850.16 EFI27722.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PIN domain DUF2985 PF11204.3 EFI27723.1 - 1.7e-24 85.3 2.8 2.7e-24 84.7 2.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) CTD_bind PF04818.8 EFI27724.1 - 8e-05 22.7 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DAP3 PF10236.4 EFI27724.1 - 0.091 11.6 0.0 0.42 9.5 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 zf-C2H2_4 PF13894.1 EFI27724.1 - 0.12 12.7 1.8 6.5 7.3 0.0 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger FAD_binding_7 PF03441.9 EFI27726.1 - 1.2e-83 280.4 0.1 3.5e-83 278.9 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EFI27726.1 - 4.7e-33 114.2 0.0 9e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.21 EFI27726.1 - 0.088 13.0 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Universal stress protein family Herpes_UL49_5 PF05702.6 EFI27728.1 - 0.066 13.0 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein DUF2370 PF10176.4 EFI27730.1 - 1.8e-66 223.8 0.0 1.8e-66 223.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) Acetyltransf_1 PF00583.19 EFI27731.1 - 7.2e-12 45.1 0.4 1.5e-11 44.1 0.3 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EFI27731.1 - 8.9e-07 28.9 0.1 2.3e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EFI27731.1 - 3.2e-05 24.0 0.0 7.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EFI27731.1 - 4.7e-05 23.3 0.0 6.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EFI27731.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EFI27731.1 - 0.00027 21.1 0.1 0.00079 19.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EFI27731.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EFI27731.1 - 0.098 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase WW PF00397.21 EFI27732.1 - 0.013 15.3 0.1 0.013 15.3 0.1 2.1 2 0 0 2 2 2 0 WW domain DUF952 PF06108.7 EFI27733.1 - 7.4e-23 80.2 0.0 1.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) UbiA PF01040.13 EFI27734.1 - 6.5e-34 117.3 16.4 9.4e-34 116.7 11.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Rho_GDI PF02115.12 EFI27735.1 - 1.2e-51 175.0 0.0 1.3e-51 174.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.10 EFI27735.1 - 0.034 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain E1_DerP2_DerF2 PF02221.10 EFI27735.1 - 0.15 12.3 0.2 0.54 10.5 0.2 2.0 1 1 0 1 1 1 0 ML domain Adap_comp_sub PF00928.16 EFI27737.1 - 3.2e-53 180.5 0.0 4.2e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EFI27737.1 - 0.00017 21.2 0.1 0.00031 20.4 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MS_channel PF00924.13 EFI27738.1 - 9.1e-15 54.5 0.2 1.4e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 EFI27738.1 - 0.0059 16.7 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EFI27738.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 EFI27738.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair C2 PF00168.25 EFI27740.1 - 3.5e-12 46.0 0.0 8.2e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Inh PF02974.9 EFI27742.1 - 0.024 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Protease inhibitor Inh Pkinase PF00069.20 EFI27744.1 - 3.5e-68 229.5 0.0 4.9e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27744.1 - 2.6e-32 111.8 0.0 4.3e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI27744.1 - 0.00047 19.2 0.8 0.89 8.4 0.0 3.3 4 0 0 4 4 4 2 Kinase-like AMMECR1 PF01871.12 EFI27745.1 - 1.3e-39 135.0 0.0 2.2e-38 131.0 0.0 2.0 1 1 0 1 1 1 1 AMMECR1 Ribosomal_S7e PF01251.13 EFI27746.1 - 6.2e-85 283.4 4.3 1.1e-84 282.6 3.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_11 PF13414.1 EFI27746.1 - 7e-18 64.0 2.1 4e-17 61.6 0.1 2.4 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 EFI27746.1 - 3.7e-10 38.9 6.1 0.00014 21.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EFI27746.1 - 2.8e-06 26.8 4.4 0.021 14.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EFI27746.1 - 0.0028 17.7 2.8 0.012 15.7 1.8 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EFI27746.1 - 0.031 14.6 0.7 14 6.1 0.7 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EFI27746.1 - 0.21 11.8 1.3 34 4.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_cyclohydroI PF01227.17 EFI27749.1 - 2.2e-64 216.0 0.0 2.8e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EFI27749.1 - 0.00061 19.6 0.0 0.0035 17.2 0.0 2.0 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 EFI27749.1 - 0.033 13.9 0.1 0.061 13.1 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Tho2 PF11262.3 EFI27750.1 - 1.9e-49 168.3 0.0 4.3e-49 167.1 0.0 1.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EFI27750.1 - 3.2e-25 87.7 0.0 8.1e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Glyco_hydro_3_C PF01915.17 EFI27751.1 - 3.7e-64 216.3 0.0 1.3e-63 214.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EFI27751.1 - 2.1e-61 207.5 0.0 3e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EFI27751.1 - 1.1e-20 73.3 2.2 1.8e-20 72.6 0.8 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EFI27751.1 - 0.0031 17.1 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 EFI27751.1 - 0.014 15.4 0.3 0.13 12.3 0.0 2.5 3 0 0 3 3 3 0 CARDB fn3 PF00041.16 EFI27751.1 - 0.037 14.1 0.8 0.26 11.4 0.0 2.6 3 0 0 3 3 3 0 Fibronectin type III domain MutL_C PF08676.6 EFI27752.1 - 4.5e-07 29.5 0.1 1.8e-05 24.3 0.1 3.2 1 1 0 1 1 1 1 MutL C terminal dimerisation domain TusA PF01206.12 EFI27752.1 - 0.097 12.2 0.0 0.45 10.1 0.0 2.2 1 0 0 1 1 1 0 Sulfurtransferase TusA HATPase_c_3 PF13589.1 EFI27753.1 - 1.9e-08 34.0 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EFI27753.1 - 2.4e-07 30.4 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EFI27753.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain Carboxyl_trans PF01039.17 EFI27754.1 - 2.1e-138 461.7 0.2 2.6e-138 461.4 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain SKN1 PF03935.10 EFI27755.1 - 1.3e-172 574.5 7.9 5e-166 552.7 5.3 3.0 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EFI27755.1 - 1.6e-07 30.7 0.2 5.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 RhoGEF PF00621.15 EFI27757.1 - 3.2e-36 124.9 0.1 9e-36 123.4 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain Nucleoporin2 PF04096.9 EFI27761.1 - 4.7e-44 149.6 0.0 7.1e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EFI27761.1 - 7.1e-31 106.7 328.6 1.4e-08 34.9 37.6 9.4 4 2 4 8 8 8 5 Nucleoporin FG repeat region HIG_1_N PF04588.8 EFI27762.1 - 0.00042 19.9 0.6 0.00042 19.9 0.4 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF3510 PF12022.3 EFI27763.1 - 0.032 14.3 0.7 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) PGAP1 PF07819.8 EFI27764.1 - 2.5e-50 171.1 0.0 3.7e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EFI27764.1 - 6.7e-11 42.1 0.2 3.5e-10 39.8 0.2 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EFI27764.1 - 9.4e-08 32.2 0.7 2.4e-07 30.8 0.5 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EFI27764.1 - 0.00064 19.3 0.2 0.046 13.3 0.1 2.3 1 1 1 2 2 2 1 Lipase (class 3) DUF915 PF06028.6 EFI27764.1 - 0.01 14.9 0.0 0.067 12.2 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 EFI27764.1 - 0.017 14.7 0.0 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2235 PF09994.4 EFI27764.1 - 0.27 10.5 0.0 0.46 9.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) TFIIB PF00382.14 EFI27766.1 - 9.1e-37 124.7 0.1 4.5e-21 74.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EFI27766.1 - 5.5e-15 54.4 1.8 9.9e-15 53.5 1.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EFI27766.1 - 0.057 12.9 0.1 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain UNC45-central PF11701.3 EFI27766.1 - 0.1 12.2 0.1 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central HTH_23 PF13384.1 EFI27766.1 - 0.11 12.2 0.0 0.97 9.1 0.0 2.5 3 0 0 3 3 3 0 Homeodomain-like domain HTH_5 PF01022.15 EFI27766.1 - 0.12 12.0 0.0 20 4.9 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Guanylin PF02058.10 EFI27766.1 - 0.14 12.2 2.0 11 6.1 0.1 2.9 1 1 2 3 3 3 0 Guanylin precursor Abhydrolase_6 PF12697.2 EFI27767.1 - 2e-32 112.8 0.0 2.8e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EFI27767.1 - 5.2e-23 81.8 0.0 4.4e-17 62.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EFI27767.1 - 4e-12 46.1 0.0 8e-12 45.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EFI27767.1 - 3.8e-07 28.8 0.0 7.4e-07 27.9 0.0 1.4 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EFI27767.1 - 0.041 13.7 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Amidase_2 PF01510.20 EFI27767.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase CDC14 PF08045.6 EFI27768.1 - 9.8e-34 116.6 0.0 2.4e-29 102.2 0.0 2.1 2 0 0 2 2 2 2 Cell division control protein 14, SIN component DUF605 PF04652.11 EFI27768.1 - 7.7 5.8 23.2 13 5.0 16.1 1.4 1 0 0 1 1 1 0 Vta1 like MRP-L47 PF06984.8 EFI27769.1 - 0.042 13.7 0.1 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Zn_clus PF00172.13 EFI27772.1 - 7.6e-06 25.7 2.7 1.3e-05 25.0 1.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pacs-1 PF10254.4 EFI27775.1 - 0.05 12.2 1.0 0.065 11.8 0.7 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein DNA_ligase_OB_2 PF14743.1 EFI27777.1 - 0.083 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 DNA ligase OB-like domain 2OG-FeII_Oxy_3 PF13640.1 EFI27778.1 - 2e-10 41.0 0.1 3.2e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EFI27778.1 - 0.022 14.3 0.4 0.097 12.3 0.1 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 EFI27778.1 - 0.042 13.8 0.1 0.43 10.5 0.1 2.5 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Tet_JBP PF12851.2 EFI27778.1 - 0.096 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EFI27779.1 - 2.1e-10 41.0 0.0 3.7e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EFI27779.1 - 0.00046 19.7 0.1 0.0027 17.3 0.0 2.3 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily GatB_N PF02934.10 EFI27780.1 - 1e-102 342.9 0.0 1.4e-102 342.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EFI27780.1 - 3.1e-29 101.5 0.8 3.2e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 GatB domain Ndc1_Nup PF09531.5 EFI27780.1 - 0.083 11.3 0.3 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF262 PF03235.9 EFI27781.1 - 1.6e-16 60.9 0.9 6.9e-16 58.8 0.1 2.4 1 1 0 1 1 1 1 Protein of unknown function DUF262 4HBT PF03061.17 EFI27782.1 - 6.5e-07 29.3 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily F-box PF00646.28 EFI27784.1 - 0.013 15.1 0.1 0.033 13.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain Vps53_N PF04100.7 EFI27784.1 - 0.2 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal F-box-like PF12937.2 EFI27785.1 - 3.8e-21 74.5 19.1 1.6e-10 40.4 1.2 4.0 3 0 0 3 3 3 3 F-box-like LRR_4 PF12799.2 EFI27785.1 - 4.1e-05 23.0 8.7 6 6.6 0.0 8.4 7 2 2 9 9 9 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EFI27785.1 - 0.0021 17.7 9.6 0.44 10.3 0.1 7.0 8 1 0 8 8 8 1 Leucine rich repeat DUF3469 PF11952.3 EFI27785.1 - 0.076 12.7 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) DUF1834 PF08873.6 EFI27785.1 - 0.22 11.0 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1834) FlxA PF14282.1 EFI27785.1 - 0.94 9.4 0.9 1.7 8.6 0.6 1.3 1 0 0 1 1 1 0 FlxA-like protein Dicty_REP PF05086.7 EFI27786.1 - 3.7 5.1 11.2 5.4 4.6 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M24 PF00557.19 EFI27787.1 - 3.9e-46 157.2 0.0 4.7e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 MoCF_biosynth PF00994.19 EFI27789.1 - 7.3e-61 203.7 0.3 2.9e-30 104.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EFI27789.1 - 1.5e-34 118.7 0.4 2.5e-34 117.9 0.2 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EFI27789.1 - 5.9e-10 38.9 0.1 2.3e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) RasGAP PF00616.14 EFI27794.1 - 4.2e-26 91.8 0.0 1.9e-15 57.0 0.0 2.5 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EFI27794.1 - 1.8e-05 24.6 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 EFI27794.1 - 9.5e-05 22.2 0.9 0.00033 20.4 0.1 2.3 2 0 0 2 2 2 1 Cell morphogenesis C-terminal SecIII_SopE_N PF05364.9 EFI27794.1 - 0.016 15.0 0.5 0.052 13.3 0.3 1.8 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus F-box-like PF12937.2 EFI27799.1 - 7.7e-10 38.3 0.6 1.6e-09 37.2 0.3 1.7 2 0 0 2 2 2 1 F-box-like FlxA PF14282.1 EFI27799.1 - 0.096 12.6 0.2 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF1843 PF08898.5 EFI27799.1 - 0.23 11.5 1.0 0.37 10.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DEAD PF00270.24 EFI27802.1 - 8.6e-19 67.6 0.0 2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EFI27802.1 - 1.4e-08 34.8 0.0 1.6e-07 31.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EFI27802.1 - 6.4e-08 32.3 0.2 2.5e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.11 EFI27802.1 - 0.089 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein F-box-like PF12937.2 EFI27803.1 - 8.5e-08 31.8 2.3 1.3e-07 31.2 0.7 2.1 2 0 0 2 2 2 1 F-box-like DivIC PF04977.10 EFI27803.1 - 0.0021 17.5 0.9 0.0038 16.6 0.6 1.4 1 0 0 1 1 1 1 Septum formation initiator WD40_alt PF14077.1 EFI27803.1 - 0.04 13.5 0.1 0.086 12.4 0.1 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif CASP_C PF08172.7 EFI27803.1 - 0.11 11.4 0.7 0.21 10.5 0.5 1.3 1 0 0 1 1 1 0 CASP C terminal MerR-DNA-bind PF09278.6 EFI27803.1 - 0.19 12.1 2.5 0.45 10.9 1.7 1.6 1 0 0 1 1 1 0 MerR, DNA binding AT_hook PF02178.14 EFI27810.1 - 0.0039 16.6 23.3 0.18 11.5 4.5 3.2 2 0 0 2 2 2 2 AT hook motif DUF605 PF04652.11 EFI27810.1 - 6.9 5.9 20.3 10 5.3 14.1 1.2 1 0 0 1 1 1 0 Vta1 like GATA PF00320.22 EFI27811.1 - 2.7e-13 48.9 3.7 2.7e-13 48.9 2.6 2.3 3 0 0 3 3 3 1 GATA zinc finger Coatomer_WDAD PF04053.9 EFI27813.1 - 3.3e-25 88.8 0.0 4.3e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region RNA_pol_3_Rpc31 PF11705.3 EFI27813.1 - 0.017 15.0 15.5 0.021 14.7 10.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 EFI27813.1 - 0.065 11.9 25.7 0.077 11.7 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EFI27813.1 - 0.58 9.7 15.0 0.8 9.2 10.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 EFI27813.1 - 1.2 6.9 6.7 1.4 6.7 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BTV_NS2 PF04514.7 EFI27813.1 - 1.5 7.6 5.3 1.7 7.4 3.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RXT2_N PF08595.6 EFI27813.1 - 5 6.9 11.9 6.4 6.5 8.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Coatomer_WDAD PF04053.9 EFI27814.1 - 1.4e-06 27.3 0.0 1.6e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Coatomer WD associated region DUF4401 PF14351.1 EFI27815.1 - 0.00066 18.7 0.7 0.0008 18.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) AmoA PF05145.7 EFI27815.1 - 0.019 14.0 0.9 0.022 13.8 0.6 1.0 1 0 0 1 1 1 0 Putative ammonia monooxygenase CD20 PF04103.10 EFI27815.1 - 0.032 14.1 1.5 0.04 13.8 1.0 1.2 1 0 0 1 1 1 0 CD20-like family DUF3649 PF12365.3 EFI27815.1 - 0.041 13.3 0.2 0.041 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) COX4_pro PF03626.9 EFI27815.1 - 0.081 13.0 2.1 0.13 12.3 1.5 1.2 1 0 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV VIT1 PF01988.14 EFI27815.1 - 0.081 12.3 1.0 0.1 12.0 0.7 1.0 1 0 0 1 1 1 0 VIT family NACHT PF05729.7 EFI27817.1 - 9e-05 22.1 0.0 0.47 10.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 EFI27817.1 - 0.0056 16.6 1.1 0.058 13.3 0.7 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EFI27817.1 - 0.017 15.2 0.2 2.1 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 EFI27817.1 - 0.018 15.2 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EFI27817.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EFI27817.1 - 0.17 12.0 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF1996 PF09362.5 EFI27818.1 - 1.9e-69 233.9 0.0 2.5e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) JAB PF01398.16 EFI27819.1 - 7.7e-12 44.9 0.0 9.6e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EFI27819.1 - 0.00081 18.9 0.0 0.00087 18.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3081 PF11280.3 EFI27819.1 - 0.096 12.2 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) Aldo_ket_red PF00248.16 EFI27822.1 - 1.1e-61 208.1 0.0 1.7e-61 207.5 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Peptidase_S9 PF00326.16 EFI27825.1 - 3.1e-39 134.4 0.0 4.3e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EFI27825.1 - 1.1e-10 41.4 0.0 2.5e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EFI27825.1 - 7.1e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 EFI27825.1 - 7.7e-06 24.6 0.7 0.0034 15.9 0.1 3.6 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EFI27825.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EFI27825.1 - 2.1e-05 24.2 0.0 4.5e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EFI27825.1 - 0.00015 21.7 0.0 0.00036 20.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EFI27825.1 - 0.0012 18.5 0.0 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EFI27825.1 - 0.0032 16.9 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EFI27825.1 - 0.018 14.6 0.0 0.15 11.5 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.9 EFI27825.1 - 0.022 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Peptidase_S15 PF02129.13 EFI27825.1 - 0.03 13.7 0.0 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF829 PF05705.9 EFI27825.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) MFS_1 PF07690.11 EFI27826.1 - 1.1e-24 86.8 24.2 2.7e-24 85.5 16.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MTP18 PF10558.4 EFI27826.1 - 0.051 13.4 0.2 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) DUF1772 PF08592.6 EFI27826.1 - 0.12 12.1 4.1 4.8 6.9 1.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Pkinase PF00069.20 EFI27827.1 - 3.7e-13 49.2 0.0 5.6e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27827.1 - 0.00014 21.0 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EFI27827.1 - 0.00023 20.9 0.2 0.13 11.9 0.1 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EFI27828.1 - 2.2e-05 23.7 0.0 3.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI27828.1 - 0.05 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase F-box-like PF12937.2 EFI27829.1 - 3.7e-05 23.3 2.1 8.1e-05 22.2 1.5 1.6 1 0 0 1 1 1 1 F-box-like ALIX_LYPXL_bnd PF13949.1 EFI27829.1 - 0.042 12.8 0.2 0.07 12.0 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV TMF_TATA_bd PF12325.3 EFI27829.1 - 0.044 13.5 0.3 0.078 12.7 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EFI27829.1 - 0.064 12.8 0.4 0.1 12.1 0.3 1.2 1 0 0 1 1 1 0 IncA protein F-box-like_2 PF13013.1 EFI27829.1 - 0.069 12.8 0.2 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain Syntaxin PF00804.20 EFI27829.1 - 0.1 12.7 0.4 0.19 11.8 0.3 1.4 1 0 0 1 1 1 0 Syntaxin Lectin_N PF03954.9 EFI27829.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Atg14 PF10186.4 EFI27829.1 - 0.13 11.1 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EFI27829.1 - 0.32 10.5 1.7 0.76 9.3 0.5 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3584 PF12128.3 EFI27829.1 - 0.46 7.7 0.9 0.65 7.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF730 PF05325.6 EFI27830.1 - 0.052 13.3 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF730) DUF21 PF01595.15 EFI27832.1 - 1.3e-30 106.0 1.1 2e-30 105.4 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EFI27832.1 - 0.00024 20.8 0.0 0.084 12.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain CopD PF05425.8 EFI27832.1 - 0.96 9.6 6.9 3.3 7.9 1.1 3.1 3 0 0 3 3 3 0 Copper resistance protein D WD40 PF00400.27 EFI27834.1 - 4e-54 178.6 17.9 7e-09 35.2 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EFI27834.1 - 0.00088 18.1 0.1 0.081 11.6 0.0 2.5 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EFI27834.1 - 0.0097 14.0 1.9 2.5 6.1 0.6 3.9 1 1 2 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EFI27834.1 - 0.053 13.3 0.2 12 5.7 0.0 3.5 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 EFI27834.1 - 0.081 12.3 0.7 2.1 7.7 0.5 2.6 1 1 0 1 1 1 0 PQQ-like domain Shisa PF13908.1 EFI27835.1 - 0.03 14.4 1.2 0.032 14.4 0.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF2668 PF10873.3 EFI27835.1 - 3 7.9 6.2 3 8.0 3.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) PCNA_N PF00705.13 EFI27836.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain TPR_14 PF13428.1 EFI27841.1 - 6.8e-11 41.7 11.9 4.5e-05 23.7 0.1 4.9 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EFI27841.1 - 3.2e-09 36.0 9.1 0.00017 21.2 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EFI27841.1 - 8.3e-09 34.9 2.5 6.4e-05 22.5 0.0 3.6 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.1 EFI27841.1 - 1.3e-08 35.0 2.3 2.6e-05 24.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EFI27841.1 - 9.4e-07 28.1 7.5 0.0007 19.0 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EFI27841.1 - 1.1e-06 27.9 0.1 0.23 11.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EFI27841.1 - 3.4e-06 26.8 0.4 3.7 7.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EFI27841.1 - 4e-05 23.4 4.7 0.0035 17.2 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EFI27841.1 - 5.7e-05 23.6 11.8 0.00093 19.8 0.5 4.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EFI27841.1 - 0.00028 20.4 1.4 0.44 10.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EFI27841.1 - 0.0006 19.8 0.5 0.034 14.2 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EFI27841.1 - 0.003 16.6 0.2 0.27 10.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EFI27841.1 - 0.051 14.0 0.3 0.051 14.0 0.2 4.3 3 0 0 3 3 2 0 Tetratricopeptide repeat Peptidase_M24 PF00557.19 EFI27842.1 - 5.8e-57 192.6 0.0 7.5e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EFI27842.1 - 1.2e-16 60.3 0.0 2.3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TC1 PF15063.1 EFI27844.1 - 0.058 12.9 0.5 0.2 11.2 0.3 1.9 1 0 0 1 1 1 0 Thyroid cancer protein 1 CIAPIN1 PF05093.8 EFI27844.1 - 0.084 12.9 8.9 0.15 12.1 0.1 3.0 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis IncA PF04156.9 EFI27846.1 - 0.06 12.9 2.2 0.13 11.8 1.5 1.6 1 0 0 1 1 1 0 IncA protein Haem_bd PF14376.1 EFI27850.1 - 0.17 11.6 0.8 15 5.2 0.1 2.2 2 0 0 2 2 2 0 Haem-binding domain IL12p40_C PF10420.4 EFI27850.1 - 0.44 10.6 3.0 15 5.7 0.4 2.4 2 1 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus DUF883 PF05957.8 EFI27851.1 - 0.08 13.3 0.2 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Streptin-Immun PF11083.3 EFI27851.1 - 0.11 12.5 0.6 4.8 7.2 0.0 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein p450 PF00067.17 EFI27854.1 - 1.1e-29 103.3 0.0 1.9e-19 69.5 0.0 3.4 2 2 0 2 2 2 2 Cytochrome P450 Metallothio_PEC PF02068.11 EFI27858.1 - 1.8 9.0 6.4 1.6 9.1 3.1 2.0 1 1 0 1 1 1 0 Plant PEC family metallothionein FlaC_arch PF05377.6 EFI27861.1 - 0.068 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.1 EFI27861.1 - 0.12 12.4 0.1 8.3 6.5 0.0 2.7 2 1 0 2 2 2 0 Syntaxin-like protein AT_hook PF02178.14 EFI27862.1 - 0.00096 18.5 0.7 0.0033 16.9 0.5 2.0 1 0 0 1 1 1 1 AT hook motif DivIC PF04977.10 EFI27864.1 - 1.1 8.8 3.3 0.71 9.3 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.2 EFI27865.1 - 5.6e-06 25.9 0.5 2.1e-05 24.1 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EFI27866.1 - 0.038 13.7 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 F-box-like Cpn60_TCP1 PF00118.19 EFI27869.1 - 2.8e-142 474.7 0.5 3.2e-142 474.5 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BAP PF06639.6 EFI27869.1 - 0.02 14.5 0.4 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) Metallophos PF00149.23 EFI27870.1 - 1.4e-42 145.3 1.1 1.8e-42 145.0 0.8 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 EFI27870.1 - 0.26 11.1 0.9 0.55 10.1 0.6 1.5 1 0 0 1 1 1 0 cwf21 domain TRAP-gamma PF07074.7 EFI27871.1 - 0.17 11.3 0.7 0.29 10.6 0.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) CRAL_TRIO PF00650.15 EFI27874.1 - 6.4e-23 80.9 0.0 1.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EFI27874.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain SspB PF04386.8 EFI27874.1 - 0.26 10.9 1.8 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Stringent starvation protein B Abhydrolase_1 PF00561.15 EFI27876.1 - 1.9e-30 106.1 0.0 1.8e-29 102.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EFI27876.1 - 6.5e-28 98.1 0.0 9e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EFI27876.1 - 4.2e-14 52.5 0.0 2.1e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EFI27876.1 - 0.017 14.9 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 EFI27876.1 - 0.017 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.9 EFI27876.1 - 0.066 11.6 0.0 0.096 11.1 0.0 1.2 1 0 0 1 1 1 0 Ndr family Peptidase_S28 PF05577.7 EFI27876.1 - 0.079 11.5 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Sad1_UNC PF07738.8 EFI27877.1 - 2.3e-24 85.7 0.0 2.7e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DivIC PF04977.10 EFI27877.1 - 0.027 13.9 0.9 0.087 12.3 0.6 1.8 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EFI27877.1 - 0.03 13.9 0.8 0.3 10.6 0.6 2.3 1 1 0 1 1 1 0 IncA protein Atg14 PF10186.4 EFI27877.1 - 0.14 11.1 3.9 0.26 10.1 2.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Adeno_GP19K PF04881.8 EFI27878.1 - 0.092 12.4 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Adenovirus GP19K eIF-5_eIF-2B PF01873.12 EFI27879.1 - 4.4e-41 139.4 0.1 7.2e-41 138.7 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EFI27879.1 - 1.2e-29 102.1 0.3 3.8e-29 100.4 0.0 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NUDIX PF00293.23 EFI27880.1 - 4.1e-14 52.3 0.3 5.4e-14 51.9 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain zf-C2H2 PF00096.21 EFI27882.1 - 7.5e-06 25.9 9.4 0.00018 21.6 1.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type IBR PF01485.16 EFI27882.1 - 0.00069 19.4 4.0 0.33 10.8 0.1 3.3 2 1 1 3 3 3 2 IBR domain zf-C2H2_4 PF13894.1 EFI27882.1 - 0.00085 19.4 9.0 0.25 11.7 0.0 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EFI27882.1 - 0.039 13.8 0.2 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EFI27882.1 - 0.091 13.0 11.2 0.58 10.5 1.7 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Inhibitor_I67 PF11405.3 EFI27882.1 - 2.7 8.1 7.2 6.3 6.9 0.4 2.8 3 0 0 3 3 3 0 Bromelain inhibitor VI NPR3 PF03666.8 EFI27887.1 - 2.7e-63 214.0 0.5 3.6e-63 213.6 0.0 1.4 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Ras PF00071.17 EFI27889.1 - 3.1e-47 159.9 0.0 3.7e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EFI27889.1 - 2.1e-22 79.8 0.1 3.1e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EFI27889.1 - 1.4e-05 24.9 0.2 2.7e-05 24.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EFI27889.1 - 1.6e-05 24.2 0.1 1.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EFI27889.1 - 9.2e-05 21.9 0.0 0.00021 20.8 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KTI12 PF08433.5 EFI27889.1 - 0.038 13.2 0.6 0.4 9.8 0.0 2.4 2 1 1 3 3 3 0 Chromatin associated protein KTI12 FeoB_N PF02421.13 EFI27889.1 - 0.045 13.0 0.0 0.094 11.9 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.1 EFI27889.1 - 0.049 13.6 0.3 0.1 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EFI27889.1 - 0.059 12.5 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.1 EFI27889.1 - 0.072 13.0 0.1 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EFI27889.1 - 0.14 12.2 0.2 1.4 9.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 EFI27890.1 - 4.9e-49 166.0 0.0 2.6e-47 160.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EFI27890.1 - 5e-10 39.0 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EFI27890.1 - 4.2e-05 23.4 0.0 0.00017 21.5 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EFI27890.1 - 0.0099 15.4 0.0 0.081 12.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EFI27890.1 - 0.018 15.2 0.0 3.6 7.8 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_5 PF12695.2 EFI27891.1 - 1.4e-10 41.1 0.4 2.1e-10 40.5 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EFI27891.1 - 9.5e-10 38.7 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EFI27891.1 - 1.9e-06 27.2 0.0 3.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Helicase_C PF00271.26 EFI27891.1 - 1.1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoPQ_related PF10142.4 EFI27891.1 - 0.014 13.9 0.0 0.017 13.6 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein RAM PF15320.1 EFI27891.1 - 0.47 10.7 3.8 0.96 9.7 2.6 1.4 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein MARVEL PF01284.18 EFI27892.1 - 5.6e-09 35.9 7.2 8.3e-09 35.4 5.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3112 PF11309.3 EFI27892.1 - 0.67 9.7 4.8 2.8 7.7 3.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) PMT PF02366.13 EFI27892.1 - 1.7 7.9 10.7 0.093 12.0 3.2 1.9 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Podoplanin PF05808.6 EFI27893.1 - 0.0012 18.3 4.8 0.0027 17.2 3.3 1.6 1 1 0 1 1 1 1 Podoplanin VSP PF03302.8 EFI27893.1 - 0.12 10.9 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-CCHC PF00098.18 EFI27894.1 - 0.029 14.2 3.5 0.029 14.2 2.4 2.9 1 1 2 3 3 3 0 Zinc knuckle Zn_Tnp_IS1595 PF12760.2 EFI27894.1 - 0.08 12.7 8.9 0.12 12.1 6.2 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-CCHC_6 PF15288.1 EFI27894.1 - 0.086 12.5 0.6 0.086 12.5 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Zn-ribbon_8 PF09723.5 EFI27894.1 - 0.36 10.8 4.1 2.9 7.9 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 EFI27894.1 - 0.44 9.9 4.5 1.6 8.2 0.3 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain YhfH PF14149.1 EFI27894.1 - 0.63 9.8 5.4 1.1 9.0 3.8 1.4 1 0 0 1 1 1 0 YhfH-like protein zf-CCHC_3 PF13917.1 EFI27894.1 - 0.89 9.3 12.4 4 7.2 8.6 2.0 1 1 0 1 1 1 0 Zinc knuckle zf-Mss51 PF13824.1 EFI27894.1 - 3.4 7.5 8.3 16 5.4 5.7 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4413 PF14372.1 EFI27895.1 - 0.027 14.4 0.2 0.1 12.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.9 EFI27895.1 - 0.03 13.9 0.0 0.089 12.4 0.0 1.8 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Complex1_LYR PF05347.10 EFI27898.1 - 1.3e-11 44.0 0.7 1.3e-11 44.0 0.5 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EFI27898.1 - 6.7e-11 42.2 1.7 1.2e-10 41.4 1.2 1.6 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EFI27898.1 - 0.0061 17.0 0.8 0.0074 16.7 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_18 PF12847.2 EFI27899.1 - 2e-11 44.4 0.0 3.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI27899.1 - 2.6e-09 36.8 0.0 5.6e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EFI27899.1 - 0.00043 20.3 0.0 0.0016 18.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EFI27899.1 - 0.00084 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EFI27899.1 - 0.0086 16.5 0.1 1.4 9.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain DUF1422 PF07226.6 EFI27899.1 - 0.029 14.1 0.2 0.063 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Methyltransf_12 PF08242.7 EFI27899.1 - 0.057 13.8 0.2 0.26 11.8 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Aconitase PF00330.15 EFI27900.1 - 8.4e-69 232.2 1.3 3.8e-40 137.7 0.1 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EFI27900.1 - 4.5e-19 68.8 0.1 1e-18 67.7 0.1 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain AIG2 PF06094.7 EFI27900.1 - 2.6e-11 43.9 0.0 5.8e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 AIG2-like family DUF2392 PF10288.4 EFI27902.1 - 1.1e-05 25.6 0.0 0.00015 22.0 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2392) DUF2616 PF11077.3 EFI27902.1 - 0.0025 17.3 0.5 0.0042 16.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2616) Coatomer_E PF04733.9 EFI27902.1 - 0.0065 15.7 0.0 0.0097 15.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit zf-C3HC4_3 PF13920.1 EFI27902.1 - 0.28 10.9 5.1 0.11 12.1 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EFI27902.1 - 1 9.2 5.2 33 4.4 1.0 2.6 2 1 1 3 3 3 0 Double zinc ribbon Cytochrome_C7 PF14522.1 EFI27902.1 - 2 8.1 4.4 42 3.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c7 adh_short PF00106.20 EFI27903.1 - 1.1e-12 48.1 0.4 2e-12 47.3 0.2 1.4 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EFI27903.1 - 5.7e-11 42.3 0.1 8e-11 41.9 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EFI27903.1 - 1.5e-05 25.0 0.4 3.3e-05 23.9 0.2 1.6 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EFI27903.1 - 0.00036 20.0 0.0 0.00045 19.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EFI27903.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EFI27903.1 - 0.0038 16.5 0.0 0.0047 16.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EFI27903.1 - 0.02 13.8 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EFI27903.1 - 0.096 12.6 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UvrD_C PF13361.1 EFI27904.1 - 1.9e-67 228.1 0.1 7.2e-67 226.3 0.1 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EFI27904.1 - 2.8e-61 207.5 0.2 1.4e-60 205.2 0.0 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EFI27904.1 - 1.8e-15 56.9 0.0 4.2e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EFI27904.1 - 3.8e-14 52.1 0.2 5.7e-13 48.4 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EFI27904.1 - 1.1e-10 41.4 0.3 0.0019 17.7 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 EFI27904.1 - 0.0011 18.4 0.1 0.0067 15.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain Vac14_Fab1_bd PF12755.2 EFI27904.1 - 0.17 12.2 0.1 0.82 10.0 0.0 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region OPT PF03169.10 EFI27905.1 - 1.7e-140 469.3 18.7 2e-140 469.2 12.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1183 PF06682.7 EFI27906.1 - 6.8e-63 213.1 1.5 2.9e-62 211.1 1.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) Citrate_synt PF00285.16 EFI27910.1 - 6.6e-79 265.2 0.0 8.4e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Sugar_tr PF00083.19 EFI27912.1 - 1.9e-38 132.2 32.6 1e-23 83.6 7.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EFI27912.1 - 1.4e-17 63.4 44.5 5.7e-13 48.3 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EFI27912.1 - 0.00017 20.1 27.1 0.0078 14.6 1.8 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein DUF1182 PF06681.8 EFI27912.1 - 0.68 9.1 5.4 0.5 9.5 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1182) Transgly_assoc PF04226.8 EFI27912.1 - 3 8.0 12.4 0.17 11.9 0.9 3.8 3 0 0 3 3 3 0 Transglycosylase associated protein WD40 PF00400.27 EFI27913.1 - 1.9e-23 81.4 8.1 8.2e-07 28.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EFI27913.1 - 0.11 10.5 0.5 0.84 7.6 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CDC45 PF02724.9 EFI27913.1 - 8.1 4.3 9.0 12 3.8 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.6 EFI27918.1 - 0.25 10.6 14.4 0.37 10.0 10.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 EFI27918.1 - 0.7 7.7 11.1 0.93 7.3 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EFI27918.1 - 1.4 7.3 12.0 1.8 6.9 8.3 1.1 1 0 0 1 1 1 0 Daxx Family Vfa1 PF08432.5 EFI27918.1 - 8 6.4 10.0 13 5.8 7.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EFI27918.1 - 8.4 4.2 8.7 11 3.9 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C14 PF00656.17 EFI27919.1 - 2.8e-20 73.0 0.0 4.2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EFI27920.1 - 3.4e-09 36.7 0.2 5.5e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Caspase domain ThiS PF02597.15 EFI27921.1 - 3.2e-05 24.2 0.0 4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 ThiS family PRMT5 PF05185.11 EFI27922.1 - 3.1e-142 474.6 0.0 1.1e-128 429.9 0.0 2.2 1 1 1 2 2 2 2 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EFI27922.1 - 0.0094 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GPI-anchored PF10342.4 EFI27923.1 - 0.081 13.4 0.4 0.081 13.4 0.3 1.8 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Adeno_PX PF05829.7 EFI27923.1 - 0.28 10.7 12.1 0.048 13.1 4.2 2.6 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) DUF4112 PF13430.1 EFI27926.1 - 4.6e-32 110.1 0.2 6e-32 109.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) APG17 PF04108.7 EFI27927.1 - 5.9e-39 134.0 22.2 5.6e-32 111.0 11.8 2.7 2 1 0 2 2 2 2 Autophagy protein Apg17 DinB_2 PF12867.2 EFI27927.1 - 0.11 12.7 3.7 8.6 6.7 0.4 3.1 2 1 1 3 3 3 0 DinB superfamily DUF1664 PF07889.7 EFI27927.1 - 0.37 10.5 11.8 0.79 9.5 0.4 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 EFI27927.1 - 0.49 10.2 7.5 8.1 6.3 0.4 3.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 EFI27927.1 - 3.1 6.7 17.9 1.3 8.0 5.3 2.9 2 1 0 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 EFI27927.1 - 3.5 6.7 23.6 2.5 7.2 1.7 4.0 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding Adeno_PIX PF03955.9 EFI27927.1 - 4.1 7.9 11.9 8.8 6.8 0.1 4.4 1 1 5 6 6 6 0 Adenovirus hexon-associated protein (IX) DUF4164 PF13747.1 EFI27927.1 - 4.4 7.5 16.8 0.098 12.8 2.1 4.0 2 2 0 3 3 3 0 Domain of unknown function (DUF4164) Nsp1_C PF05064.8 EFI27927.1 - 7.8 6.1 12.5 1.9 8.1 0.3 4.2 4 1 0 4 4 4 0 Nsp1-like C-terminal region MOZ_SAS PF01853.13 EFI27928.1 - 5e-77 257.4 0.0 7.9e-77 256.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EFI27928.1 - 1.4e-14 53.4 21.3 9e-10 38.1 1.2 3.6 3 1 0 3 3 3 2 PHD-finger Methyltransf_32 PF13679.1 EFI27928.1 - 4.2e-13 49.1 0.0 8.2e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI27928.1 - 0.0001 22.8 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI27928.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EFI27928.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EFI27928.1 - 0.038 13.3 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EFI27928.1 - 0.15 12.5 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Elf1 PF05129.8 EFI27928.1 - 0.32 10.7 4.3 1.2 8.8 3.0 2.1 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like RrnaAD PF00398.15 EFI27928.1 - 0.51 9.3 0.0 0.86 8.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF221 PF02714.10 EFI27929.1 - 1.3e-105 352.8 18.5 1.9e-105 352.3 12.8 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EFI27929.1 - 4e-35 120.7 0.5 1e-34 119.3 0.4 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EFI27929.1 - 1.5e-18 67.0 0.1 3.8e-18 65.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EFI27929.1 - 8.9e-16 57.5 0.0 1.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein 2TM PF13239.1 EFI27930.1 - 0.26 11.3 7.5 0.69 10.0 0.3 3.5 3 0 0 3 3 3 0 2TM domain Response_reg PF00072.19 EFI27931.1 - 1.4e-19 70.1 0.0 3.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EFI27931.1 - 4.6e-18 64.9 0.0 9e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EFI27931.1 - 6.2e-15 54.9 0.1 2.8e-14 52.8 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EFI27931.1 - 0.00011 22.3 0.0 0.062 13.4 0.0 2.7 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 EFI27931.1 - 0.0038 17.3 0.0 2.1 8.4 0.0 3.4 2 2 1 3 3 3 1 GAF domain Herpes_U5 PF05999.6 EFI27931.1 - 0.24 9.9 0.0 0.36 9.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus U5-like family DUF1115 PF06544.7 EFI27932.1 - 7.9e-09 35.2 0.0 1.2e-08 34.7 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Ferric_reduct PF01794.14 EFI27933.1 - 5.8e-16 58.7 13.4 5.8e-16 58.7 9.3 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EFI27933.1 - 0.0002 21.1 0.3 0.0064 16.3 0.0 3.0 3 0 0 3 3 3 1 FAD-binding domain DUF2427 PF10348.4 EFI27933.1 - 0.0021 17.6 2.5 0.0059 16.1 1.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) NAD_binding_1 PF00175.16 EFI27933.1 - 0.0068 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EFI27933.1 - 0.061 13.2 0.1 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PFK PF00365.15 EFI27934.1 - 1.4e-156 519.6 3.1 2.1e-89 299.2 0.0 3.1 3 0 0 3 3 3 3 Phosphofructokinase Yip1 PF04893.12 EFI27937.1 - 1.8e-13 50.3 15.7 2.8e-13 49.7 10.9 1.3 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 EFI27937.1 - 0.01 15.7 2.4 0.01 15.7 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1282 PF06930.7 EFI27937.1 - 0.83 9.2 11.2 1.3 8.7 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) ABC_tran PF00005.22 EFI27939.1 - 9e-38 129.6 0.1 3.9e-27 95.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EFI27939.1 - 4.3e-27 95.2 25.6 2.7e-16 59.7 1.0 3.3 2 1 1 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EFI27939.1 - 4.1e-08 33.5 0.1 0.0026 17.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EFI27939.1 - 7.9e-07 28.5 0.6 0.00051 19.3 0.0 3.0 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EFI27939.1 - 0.0057 16.6 0.5 0.017 15.0 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EFI27939.1 - 0.0077 16.1 0.3 1.2 9.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EFI27939.1 - 0.022 15.2 0.2 0.062 13.7 0.1 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EFI27939.1 - 0.052 13.0 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EFI27939.1 - 0.053 13.5 0.7 1.2 9.1 0.2 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EFI27939.1 - 0.32 11.8 1.1 1.2 10.0 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EFI27939.1 - 0.47 8.8 0.1 0.82 8.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Polysacc_deac_1 PF01522.16 EFI27941.1 - 1.1e-31 109.0 0.0 1.7e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DASH_Dad2 PF08654.5 EFI27941.1 - 0.00039 20.3 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 Ribosomal_L18e PF00828.14 EFI27942.1 - 0.016 15.5 0.0 0.017 15.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L18e/L15 Baculo_PEP_C PF04513.7 EFI27943.1 - 1.6 8.5 12.6 0.59 9.9 0.1 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EFI27943.1 - 3.1 6.9 9.5 0.93 8.6 1.1 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Noc2 PF03715.8 EFI27943.1 - 6.1 5.6 9.2 1.4 7.6 3.3 2.0 2 0 0 2 2 2 0 Noc2p family Alpha-amylase PF00128.19 EFI27944.1 - 9.5e-29 100.7 0.0 3.2e-28 99.0 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EFI27944.1 - 2.7e-07 28.7 0.6 0.15 9.8 0.1 3.7 2 1 1 3 3 3 3 Glycosyl hydrolase family 70 Fra10Ac1 PF09725.4 EFI27946.1 - 3.6e-09 36.7 3.8 6.9e-06 26.1 0.1 2.5 1 1 1 2 2 2 2 Folate-sensitive fragile site protein Fra10Ac1 Glyco_trans_1_3 PF13528.1 EFI27947.1 - 4.8e-05 22.7 0.0 0.00036 19.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 1 HTH_Tnp_ISL3 PF13542.1 EFI27947.1 - 0.13 11.4 0.1 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Aa_trans PF01490.13 EFI27948.1 - 7.2e-83 278.3 26.5 8.5e-83 278.1 18.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1656 PF07869.7 EFI27948.1 - 2.6 7.8 7.7 4.8 7.0 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Cellulase PF00150.13 EFI27950.1 - 1.9e-10 40.3 0.0 3.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apolipoprotein PF01442.13 EFI27952.1 - 0.071 12.6 1.2 0.11 11.9 0.9 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EFI27952.1 - 0.11 12.9 6.9 0.24 11.8 0.4 3.6 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Cullin PF00888.17 EFI27953.1 - 2.6e-133 445.6 0.0 6.4e-75 252.8 0.0 2.1 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 EFI27953.1 - 2.6e-28 97.6 1.0 8.7e-28 95.9 0.7 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 EFI27953.1 - 0.034 14.2 0.0 0.096 12.7 0.0 1.8 1 0 0 1 1 1 0 Penicillinase repressor DUF2533 PF10752.4 EFI27953.1 - 0.25 11.6 2.6 1.7 8.9 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2533) Antimicrobial10 PF08105.6 EFI27954.1 - 0.64 9.6 3.3 8.5 6.0 2.3 2.1 1 1 0 1 1 1 0 Metchnikowin family DnaJ PF00226.26 EFI27955.1 - 4.3e-16 58.3 0.1 7.4e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain SR-25 PF10500.4 EFI27955.1 - 2.3 7.6 9.4 3.2 7.1 6.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CTDII PF01556.13 EFI27956.1 - 2.9e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DUF1571 PF07608.6 EFI27956.1 - 0.032 13.3 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) DUF3104 PF11302.3 EFI27957.1 - 0.099 12.0 2.0 5.9 6.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3104) Pheromone PF08015.6 EFI27958.1 - 0.00016 22.4 0.8 0.23 12.3 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Foamy_BEL PF03274.9 EFI27960.1 - 0.12 11.6 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein DUF544 PF04424.8 EFI27969.1 - 1.1e-07 31.6 0.0 2.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Pheromone PF08015.6 EFI27970.1 - 0.00032 21.4 3.8 0.015 16.1 0.2 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI27971.1 - 0.04 14.7 3.8 0.53 11.1 2.6 2.3 1 1 0 1 1 1 0 Fungal mating-type pheromone CARD PF00619.16 EFI27972.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Caspase recruitment domain Dopey_N PF04118.9 EFI27975.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal F-box-like PF12937.2 EFI27977.1 - 0.00023 20.8 0.1 0.00053 19.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like UCH PF00443.24 EFI27979.1 - 2.7e-49 167.7 0.1 3.5e-29 101.7 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EFI27979.1 - 3.9e-20 72.4 0.2 9.6e-12 44.9 0.4 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SoxZ PF08770.6 EFI27979.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ RF-1 PF00472.15 EFI27981.1 - 2e-16 59.7 0.2 3.8e-16 58.9 0.1 1.4 1 1 0 1 1 1 1 RF-1 domain Lipase_3 PF01764.20 EFI27982.1 - 3.3e-13 49.4 0.0 8.2e-13 48.1 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Esterase PF00756.15 EFI27982.1 - 0.0049 16.3 0.0 0.0073 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EFI27982.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EFI27982.1 - 0.075 12.5 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein LRR_4 PF12799.2 EFI27983.1 - 0.003 17.1 1.5 0.32 10.6 0.1 3.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) Phage_lysozyme PF00959.14 EFI27985.1 - 1e-15 57.9 0.0 2.3e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Phage lysozyme DUF2360 PF10152.4 EFI27985.1 - 5 7.3 5.4 8.9 6.5 3.7 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) PIG-X PF08320.7 EFI27986.1 - 1.8e-16 60.0 0.0 2.2e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 Pheromone PF08015.6 EFI27987.1 - 3.6e-05 24.5 1.4 0.0012 19.5 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI27988.1 - 0.0001 23.0 2.0 0.0012 19.6 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI27989.1 - 1.1e-05 26.1 1.5 0.001 19.8 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI27991.1 - 1.6e-05 25.6 1.6 0.0014 19.3 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI27992.1 - 3.2e-05 24.6 1.2 0.002 18.9 0.8 2.0 1 1 0 1 1 1 1 Fungal mating-type pheromone Pheromone PF08015.6 EFI27993.1 - 1.4e-05 25.7 1.7 0.002 18.9 0.2 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone WaaY PF06176.6 EFI27995.1 - 0.05 12.8 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Peptidase_S49_N PF08496.5 EFI27995.1 - 2.5 7.8 6.4 3.6 7.3 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3886 PF13025.1 EFI27995.1 - 7.6 6.5 16.6 17 5.4 11.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Pkinase PF00069.20 EFI27999.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain CENP-B_dimeris PF09026.5 EFI28001.1 - 0.37 11.0 11.6 1.2 9.4 1.2 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_C48 PF02902.14 EFI28012.1 - 3e-05 23.7 0.1 5.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain AT_hook PF02178.14 EFI28012.1 - 0.1 12.3 20.1 0.13 12.0 4.1 3.0 2 0 0 2 2 2 0 AT hook motif SipA PF09052.5 EFI28012.1 - 1.5 7.1 6.6 2.3 6.5 4.6 1.2 1 0 0 1 1 1 0 Salmonella invasion protein A DUF897 PF05982.7 EFI28013.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF897) Kinesin-relat_1 PF12711.2 EFI28014.1 - 0.1 13.0 0.1 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinesin motor Pheromone PF08015.6 EFI28015.1 - 0.0033 18.2 0.9 0.052 14.3 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI28016.1 - 8.9e-06 26.4 1.4 5.6e-05 23.8 0.1 1.9 1 1 1 2 2 2 1 Fungal mating-type pheromone Pheromone PF08015.6 EFI28017.1 - 0.0007 20.3 3.7 0.018 15.8 0.1 2.3 1 1 1 2 2 2 2 Fungal mating-type pheromone PT PF04886.7 EFI28017.1 - 0.035 13.4 9.8 0.073 12.4 6.8 1.4 1 0 0 1 1 1 0 PT repeat Pheromone PF08015.6 EFI28018.1 - 0.0056 17.4 4.8 0.05 14.4 3.4 2.4 1 1 0 1 1 1 1 Fungal mating-type pheromone GvpL_GvpF PF06386.6 EFI28021.1 - 0.24 10.9 1.7 0.24 10.9 1.2 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF AT_hook PF02178.14 EFI28022.1 - 2 8.3 6.7 1.1 9.1 0.1 3.1 3 0 0 3 3 3 0 AT hook motif Tet_JBP PF12851.2 EFI28023.1 - 2.3e-14 53.0 0.0 3.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EFI28023.1 - 0.0076 16.7 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4164 PF13747.1 EFI28024.1 - 0.0028 17.7 2.7 0.067 13.3 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4164) FlgN PF05130.7 EFI28024.1 - 0.0037 17.5 0.1 0.0063 16.7 0.1 1.4 1 0 0 1 1 1 1 FlgN protein IncA PF04156.9 EFI28024.1 - 0.13 11.8 0.2 0.16 11.5 0.2 1.2 1 0 0 1 1 1 0 IncA protein DUF3670 PF12419.3 EFI28024.1 - 0.16 11.3 2.2 1.5 8.2 0.2 2.2 1 1 1 2 2 2 0 SNF2 Helicase protein Seryl_tRNA_N PF02403.17 EFI28024.1 - 0.6 10.1 3.7 0.6 10.1 0.2 2.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cauli_VI PF01693.11 EFI28025.1 - 9.8e-09 35.1 0.0 3e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 Caulimovirus viroplasmin F-box-like PF12937.2 EFI28027.1 - 0.00048 19.8 0.1 0.00083 19.0 0.1 1.4 1 0 0 1 1 1 1 F-box-like G-alpha PF00503.15 EFI28030.1 - 5.4e-121 403.9 0.1 1.9e-115 385.6 0.0 2.0 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EFI28030.1 - 1.3e-10 40.8 0.3 8.1e-09 34.9 0.0 2.7 3 0 0 3 3 3 2 ADP-ribosylation factor family DAHP_synth_2 PF01474.11 EFI28031.1 - 3.7e-92 308.9 0.0 4.3e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DAHP_synth_2 PF01474.11 EFI28032.1 - 8.4e-20 70.5 0.1 1.2e-18 66.6 0.0 2.7 1 1 2 3 3 3 3 Class-II DAHP synthetase family IBR PF01485.16 EFI28034.1 - 2.4e-11 43.3 18.1 8.4e-07 28.7 4.8 2.4 2 0 0 2 2 2 2 IBR domain zf-RING_3 PF14369.1 EFI28034.1 - 7.1 6.7 13.6 3.9 7.5 0.0 4.5 2 1 2 4 4 4 0 zinc-finger APH PF01636.18 EFI28035.1 - 0.0089 15.7 0.1 0.016 14.9 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1996 PF09362.5 EFI28038.1 - 8.4e-83 277.6 0.1 1e-82 277.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CBM_1 PF00734.13 EFI28038.1 - 2.3e-11 43.1 14.4 2.3e-11 43.1 10.0 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Helicase_C PF00271.26 EFI28041.1 - 1.7e-16 59.8 0.0 4.8e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EFI28041.1 - 7.9e-11 41.7 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Bestrophin PF01062.16 EFI28043.1 - 1.7e-16 60.0 0.1 4e-15 55.5 0.3 2.3 3 0 0 3 3 3 2 Bestrophin, RFP-TM, chloride channel CBM_19 PF03427.8 EFI28044.1 - 0.0073 16.0 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 19) IncA PF04156.9 EFI28046.1 - 0.0043 16.6 11.4 0.008 15.7 7.9 1.3 1 0 0 1 1 1 1 IncA protein HOOK PF05622.7 EFI28046.1 - 0.01 13.6 7.6 0.015 13.1 5.2 1.2 1 0 0 1 1 1 0 HOOK protein Leu_zip PF15294.1 EFI28046.1 - 0.019 14.1 5.0 0.032 13.3 3.5 1.3 1 0 0 1 1 1 0 Leucine zipper ERM PF00769.14 EFI28046.1 - 0.26 10.7 13.2 0.5 9.8 9.2 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UPF0242 PF06785.6 EFI28046.1 - 0.28 9.7 6.2 0.47 9.0 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) GAS PF13851.1 EFI28046.1 - 1.1 8.4 10.0 2.1 7.4 6.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 EFI28046.1 - 2.5 8.0 12.1 5 7.0 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 EFI28046.1 - 2.9 6.7 7.8 5.7 5.7 5.4 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EFI28046.1 - 3.4 6.6 7.6 5.1 6.0 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 EFI28046.1 - 4.5 7.2 17.8 2.9e+03 -1.8 12.3 3.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 F-box PF00646.28 EFI28049.1 - 4.2e-07 29.4 0.1 1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EFI28049.1 - 1.3e-05 24.8 0.0 2.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like Methyltransf_29 PF03141.11 EFI28049.1 - 0.088 11.1 0.0 2.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CBM_1 PF00734.13 EFI28051.1 - 1.3e-05 24.7 3.2 2.3e-05 23.9 2.2 1.4 1 0 0 1 1 1 1 Fungal cellulose binding domain PIF1 PF05970.9 EFI28054.1 - 2.2e-24 86.1 0.0 5.2e-24 84.8 0.0 1.6 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EFI28054.1 - 4.8e-07 29.5 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EFI28054.1 - 0.00025 20.7 0.0 0.00064 19.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EFI28054.1 - 0.002 17.7 0.1 0.3 10.6 0.0 2.9 2 1 1 3 3 3 2 AAA domain Peptidase_M22 PF00814.20 EFI28055.1 - 0.16 11.4 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 Glycoprotease family NACHT PF05729.7 EFI28061.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EFI28061.1 - 0.042 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EFI28061.1 - 0.045 13.1 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EFI28061.1 - 0.047 13.8 0.0 0.082 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EFI28061.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EFI28061.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.16 EFI28061.1 - 0.15 11.1 0.0 2.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ank PF00023.25 EFI28062.1 - 2.9e-25 86.7 1.3 5.7e-05 22.7 0.0 7.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_2 PF12796.2 EFI28062.1 - 4.2e-23 81.4 0.0 1.1e-08 35.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EFI28062.1 - 7e-23 80.1 2.1 1.3e-10 41.1 0.0 5.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EFI28062.1 - 4e-20 71.7 0.3 3.1e-06 27.5 0.1 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EFI28062.1 - 3.9e-17 60.6 0.1 0.0028 17.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Tropomyosin_1 PF12718.2 EFI28064.1 - 1.6e-07 31.2 33.9 0.00016 21.5 11.7 3.0 1 1 1 2 2 2 2 Tropomyosin like Cep57_CLD_2 PF14197.1 EFI28064.1 - 0.0053 16.6 4.8 0.0053 16.6 3.3 4.6 2 1 3 5 5 5 1 Centrosome localisation domain of PPC89 Macoilin PF09726.4 EFI28064.1 - 0.015 13.5 27.2 0.027 12.8 18.8 1.3 1 0 0 1 1 1 0 Transmembrane protein CALCOCO1 PF07888.6 EFI28064.1 - 0.018 13.3 31.2 0.065 11.5 21.4 1.7 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sipho_Gp157 PF05565.6 EFI28064.1 - 0.046 13.3 9.8 1.6 8.2 3.8 2.9 1 1 2 3 3 3 0 Siphovirus Gp157 DivIVA PF05103.8 EFI28064.1 - 0.05 13.6 35.5 0.026 14.5 11.8 3.2 1 1 1 2 2 2 0 DivIVA protein CENP-F_leu_zip PF10473.4 EFI28064.1 - 0.051 13.4 31.0 0.31 10.8 3.3 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EFI28064.1 - 0.074 12.2 32.2 0.52 9.4 0.9 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EFI28064.1 - 0.079 11.6 26.7 0.27 9.8 6.6 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein bZIP_2 PF07716.10 EFI28064.1 - 0.08 12.7 34.0 0.1 12.4 3.7 4.7 4 0 0 4 4 4 0 Basic region leucine zipper Prefoldin_2 PF01920.15 EFI28064.1 - 0.1 12.4 35.1 0.71 9.6 1.0 4.4 2 1 1 4 4 4 0 Prefoldin subunit Herpes_UL6 PF01763.11 EFI28064.1 - 0.1 10.7 23.9 0.089 10.9 4.1 2.6 1 1 1 2 2 2 0 Herpesvirus UL6 like CCDC155 PF14662.1 EFI28064.1 - 0.16 11.5 36.7 0.043 13.3 18.5 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 ERM PF00769.14 EFI28064.1 - 0.21 11.1 40.6 0.055 12.9 3.9 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 EFI28064.1 - 0.35 10.6 41.1 0.32 10.7 17.2 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4600 PF15372.1 EFI28064.1 - 0.36 11.0 24.3 0.087 13.0 5.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Ax_dynein_light PF10211.4 EFI28064.1 - 0.61 9.9 27.6 0.2 11.4 6.2 3.3 1 1 2 3 3 3 0 Axonemal dynein light chain IFT57 PF10498.4 EFI28064.1 - 0.62 8.7 27.3 0.85 8.2 8.9 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ADIP PF11559.3 EFI28064.1 - 0.67 9.8 45.3 0.11 12.3 4.2 3.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EFI28064.1 - 1.9 7.4 34.4 0.12 11.4 15.6 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Phlebovirus_NSM PF07246.6 EFI28064.1 - 1.9 7.5 15.7 0.43 9.7 7.7 1.9 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M Bacillus_HBL PF05791.6 EFI28064.1 - 2.6 7.4 17.2 0.036 13.4 1.3 2.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF342 PF03961.8 EFI28064.1 - 2.7 6.3 20.6 0.81 8.0 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Filament PF00038.16 EFI28064.1 - 3.4 7.0 38.7 0.77 9.1 7.1 3.0 2 1 0 3 3 3 0 Intermediate filament protein THOC7 PF05615.8 EFI28064.1 - 5.4 7.2 33.4 0.5 10.6 8.9 3.4 1 1 2 3 3 3 0 Tho complex subunit 7 bZIP_1 PF00170.16 EFI28064.1 - 6.1 6.8 20.0 1.4 8.9 1.1 4.2 3 1 1 4 4 4 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 EFI28064.1 - 8.1 6.5 23.7 17 5.4 0.1 3.5 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 EFI28064.1 - 8.4 5.9 34.2 0.26 10.7 5.0 4.4 3 1 1 4 4 4 0 Septum formation initiator DUF972 PF06156.8 EFI28064.1 - 8.6 6.7 26.2 4 7.8 5.2 4.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) YlqD PF11068.3 EFI28064.1 - 8.9 6.3 36.0 15 5.6 6.6 3.0 1 1 2 3 3 3 0 YlqD protein TMF_DNA_bd PF12329.3 EFI28064.1 - 9.4 6.1 31.1 0.86 9.4 1.7 4.4 2 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EFI28064.1 - 9.9 4.4 23.9 28 3.0 16.2 1.7 1 1 0 1 1 1 0 AAA domain Abhydrolase_5 PF12695.2 EFI28066.1 - 0.13 12.0 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family SpoVS PF04232.7 EFI28066.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) Abhydrolase_5 PF12695.2 EFI28067.1 - 0.097 12.4 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family MbeB_N PF04837.7 EFI28071.1 - 0.13 12.3 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 MbeB-like, N-term conserved region Kdo PF06293.9 EFI28072.1 - 3.5e-06 26.2 0.0 6.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EFI28072.1 - 0.0023 17.3 0.1 0.0055 16.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EFI28072.1 - 0.0032 17.2 0.4 0.11 12.2 0.1 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family APH_6_hur PF04655.9 EFI28072.1 - 0.015 14.4 0.0 0.071 12.2 0.0 2.0 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Choline_kinase PF01633.15 EFI28072.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2828 PF11443.3 EFI28073.1 - 1.2e-154 515.5 0.1 1.4e-154 515.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) His_Phos_2 PF00328.17 EFI28074.1 - 0.035 13.4 0.0 0.083 12.2 0.0 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) SRP72 PF08492.7 EFI28075.1 - 7.4e-10 39.0 0.4 7.4e-10 39.0 0.3 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_16 PF13432.1 EFI28075.1 - 4.1e-08 33.6 7.4 0.0056 17.3 3.6 2.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EFI28075.1 - 5.8e-08 32.9 7.5 7.5e-06 26.2 0.2 3.0 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EFI28075.1 - 6.1e-07 28.9 4.7 0.27 10.8 0.3 3.2 3 0 0 3 3 3 3 TPR repeat TPR_14 PF13428.1 EFI28075.1 - 1.2e-05 25.5 5.8 0.24 12.1 0.0 4.3 1 1 3 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EFI28075.1 - 2.8e-05 24.1 6.6 0.00084 19.4 0.9 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EFI28075.1 - 0.00011 21.9 6.9 0.0044 16.8 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EFI28075.1 - 0.00016 21.3 7.4 0.88 9.6 0.2 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EFI28075.1 - 0.0023 18.2 4.3 0.83 10.2 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EFI28075.1 - 0.026 14.1 3.1 1.1 8.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EFI28075.1 - 0.035 13.9 0.3 6.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EFI28075.1 - 0.052 13.4 6.7 0.57 10.1 0.4 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat Ceramidase_alk PF04734.8 EFI28077.1 - 3.3e-259 861.3 0.0 3.8e-259 861.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Fumarate_red_C PF02300.12 EFI28083.1 - 0.17 11.7 2.3 0.31 10.9 1.6 1.4 1 0 0 1 1 1 0 Fumarate reductase subunit C DUF4582 PF15189.1 EFI28085.1 - 0.033 13.4 2.2 0.059 12.6 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) Git3 PF11710.3 EFI28086.1 - 1.3e-08 34.7 6.0 3.4e-08 33.3 4.2 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EFI28086.1 - 6.9e-05 21.8 3.2 6.9e-05 21.8 2.2 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DUF912 PF06024.7 EFI28086.1 - 0.05 13.6 1.5 0.76 9.8 0.0 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CcmH PF03918.9 EFI28086.1 - 6.4 5.7 5.9 6 5.8 0.3 2.5 3 0 0 3 3 3 0 Cytochrome C biogenesis protein TMEM192 PF14802.1 EFI28086.1 - 7 5.4 7.5 1e+02 1.5 4.6 2.6 2 1 0 2 2 2 0 TMEM192 family F-box-like_2 PF13013.1 EFI28088.1 - 5.3e-16 58.2 0.2 9.7e-16 57.4 0.2 1.4 1 0 0 1 1 1 1 F-box-like domain LRR_4 PF12799.2 EFI28088.1 - 2.1e-05 24.0 1.1 0.76 9.4 0.1 4.3 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.28 EFI28088.1 - 0.0087 15.6 1.9 0.0097 15.5 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 EFI28089.1 - 5.7e-17 61.4 0.5 1.4e-16 60.1 0.3 1.6 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 EFI28089.1 - 0.00013 21.4 0.5 0.00044 19.8 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EFI28089.1 - 0.00022 20.8 0.3 0.00061 19.4 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EFI28090.1 - 0.027 14.1 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 EFI28091.1 - 1.5e-09 37.5 0.3 4.4e-09 36.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 EFI28091.1 - 0.0016 18.0 0.1 0.0052 16.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain Glyco_transf_8 PF01501.15 EFI28092.1 - 3.1e-08 33.2 0.0 6.5e-05 22.3 0.0 2.3 2 1 0 2 2 2 2 Glycosyl transferase family 8 OPT PF03169.10 EFI28093.1 - 4.2e-194 646.5 39.2 5e-194 646.2 27.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MSC PF09402.5 EFI28093.1 - 9.4 4.8 5.9 18 3.8 4.1 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain HUN PF08729.5 EFI28095.1 - 6.8e-07 29.0 0.3 1.5e-06 27.9 0.2 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF4482 PF14818.1 EFI28095.1 - 0.67 10.5 5.1 1.3 9.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) TMEM151 PF14857.1 EFI28097.1 - 0.012 14.2 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 0 TMEM151 family Mito_carr PF00153.22 EFI28098.1 - 5.4e-38 128.5 0.3 1.4e-11 43.8 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein F-box-like PF12937.2 EFI28099.1 - 8.9e-07 28.5 0.3 2.6e-06 27.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like Smr PF01713.16 EFI28101.1 - 1.9e-14 53.5 0.0 2.4e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Smr domain HEAT_2 PF13646.1 EFI28101.1 - 0.01 16.0 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 HEAT repeats DUF4265 PF14085.1 EFI28101.1 - 0.097 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) UvdE PF03851.9 EFI28105.1 - 1.6e-77 260.2 0.0 2.1e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE GAGA_bind PF06217.7 EFI28105.1 - 6 6.7 8.8 4.3 7.2 2.3 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family COG7 PF10191.4 EFI28106.1 - 8.8e-87 291.7 13.6 3.6e-55 187.2 2.2 3.0 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) Hist_deacetyl PF00850.14 EFI28108.1 - 2.6e-96 322.5 0.0 4.5e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EFI28108.1 - 1.2e-22 80.1 0.1 2.1e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain Voltage_CLC PF00654.15 EFI28110.1 - 3.8e-92 309.0 20.1 3.8e-92 309.0 13.9 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EFI28110.1 - 0.0023 17.6 0.0 0.0063 16.2 0.0 1.8 1 0 0 1 1 1 1 CBS domain GLTSCR1 PF15249.1 EFI28111.1 - 5.9e-24 84.2 0.2 1.1e-23 83.3 0.2 1.5 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region CCDC-167 PF15188.1 EFI28111.1 - 0.059 13.3 4.1 0.052 13.5 1.6 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Ank_4 PF13637.1 EFI28112.1 - 3.4e-10 40.1 0.0 3.2e-05 24.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EFI28112.1 - 4.7e-09 36.4 0.0 1.5e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EFI28112.1 - 5.8e-05 22.9 0.1 0.0011 18.9 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 EFI28112.1 - 6.3e-05 22.5 0.0 0.00022 20.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EFI28112.1 - 0.00018 21.6 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ribosomal_S8e PF01201.17 EFI28113.1 - 2.8e-40 137.4 4.1 9.5e-40 135.7 2.9 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 EFI28113.1 - 0.066 13.1 1.5 0.089 12.7 0.7 1.5 1 1 0 1 1 1 0 Mer2 PigN PF04987.9 EFI28115.1 - 0.0087 14.7 1.2 0.014 14.0 0.8 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) DUF2668 PF10873.3 EFI28115.1 - 0.18 11.9 0.5 0.89 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Defensin_beta_2 PF13841.1 EFI28116.1 - 0.05 13.9 3.1 0.05 13.9 2.1 2.8 2 1 1 3 3 3 0 Beta defensin EB PF01683.13 EFI28116.1 - 0.12 12.4 28.9 0.27 11.3 1.9 4.1 3 2 0 3 3 3 0 EB module Defensin_beta PF00711.14 EFI28116.1 - 4.5 7.2 10.1 3.8 7.5 0.2 3.7 3 1 0 3 3 3 0 Beta defensin GATA PF00320.22 EFI28118.1 - 1e-18 66.3 1.6 2.1e-18 65.3 1.1 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EFI28118.1 - 5.2e-13 48.3 2.8 1.2e-12 47.1 2.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SNURF PF07192.6 EFI28118.1 - 0.18 11.6 2.2 4.4 7.2 0.3 3.0 3 0 0 3 3 3 0 SNURF/RPN4 protein Sec7 PF01369.15 EFI28119.1 - 9.5e-39 133.0 0.0 2.8e-38 131.4 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EFI28119.1 - 1e-29 103.1 0.0 2.1e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 EFI28119.1 - 0.012 15.6 3.7 0.028 14.5 1.5 2.5 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PH PF00169.24 EFI28119.1 - 0.013 15.7 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 PH domain SLAC1 PF03595.12 EFI28120.1 - 1.9e-66 223.9 55.0 2.2e-66 223.7 38.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SLAC1 PF03595.12 EFI28121.1 - 4.4e-39 134.0 25.5 4.9e-39 133.8 17.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel UDPGP PF01704.13 EFI28122.1 - 4.2e-125 417.5 0.0 3.1e-102 342.2 0.0 2.0 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase HhH-GPD PF00730.20 EFI28123.1 - 2.9e-18 66.1 0.0 5.2e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Oxidored_q6 PF01058.17 EFI28124.1 - 1.8e-22 79.3 0.1 2.9e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Amidohydro_4 PF13147.1 EFI28127.1 - 1.7e-07 31.5 0.1 2.4e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EFI28127.1 - 0.00097 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EFI28127.1 - 0.015 15.0 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family MRP-S33 PF08293.6 EFI28128.1 - 3e-25 88.0 0.2 3.9e-25 87.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Astro_capsid_p PF12226.3 EFI28128.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein F-box-like PF12937.2 EFI28129.1 - 2.3e-07 30.4 0.4 1e-06 28.3 0.3 2.2 1 0 0 1 1 1 1 F-box-like Acetyltransf_1 PF00583.19 EFI28130.1 - 2.5e-06 27.4 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EFI28130.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EFI28130.1 - 0.0041 17.0 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EFI28130.1 - 0.0055 16.8 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EFI28130.1 - 0.014 15.5 0.0 0.052 13.6 0.0 1.8 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EFI28130.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fcf1 PF04900.7 EFI28132.1 - 2.3e-40 136.7 0.7 2.3e-40 136.7 0.5 1.6 2 0 0 2 2 2 1 Fcf1 Lyase_aromatic PF00221.14 EFI28134.1 - 1.3e-157 525.0 0.7 1.7e-157 524.6 0.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase DAO PF01266.19 EFI28135.1 - 1.8e-31 109.3 0.0 2.7e-31 108.7 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EFI28135.1 - 1.3e-07 31.6 0.1 0.0025 17.7 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EFI28135.1 - 1.6e-05 23.9 0.1 0.0017 17.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EFI28135.1 - 5.6e-05 22.1 0.0 0.0081 15.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EFI28135.1 - 0.00022 21.1 0.0 0.00087 19.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EFI28135.1 - 0.00055 19.7 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EFI28135.1 - 0.0047 15.4 0.0 0.59 8.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EFI28135.1 - 0.0054 16.8 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EFI28135.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.13 EFI28135.1 - 0.036 14.0 0.0 0.16 12.0 0.0 2.0 2 1 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 EFI28135.1 - 0.052 12.4 0.1 1.1 8.1 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EFI28135.1 - 0.059 12.4 0.0 0.49 9.4 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 EFI28135.1 - 0.064 13.3 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EFI28135.1 - 0.086 11.7 0.0 0.71 8.7 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DNA_RNApol_7kD PF03604.8 EFI28135.1 - 0.095 12.1 1.2 0.22 11.0 0.8 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit 3HCDH_N PF02737.13 EFI28135.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tyrosinase PF00264.15 EFI28136.1 - 9.1e-55 186.2 1.7 1.3e-54 185.7 0.5 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Glyco_transf_8 PF01501.15 EFI28137.1 - 2.2e-12 46.8 0.0 1.1e-11 44.5 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 8 DUF1917 PF08939.5 EFI28138.1 - 1.1e-31 110.4 0.1 1.1e-31 110.4 0.1 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1917) SAP PF02037.22 EFI28138.1 - 0.057 12.9 0.6 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 SAP domain ComK PF06338.6 EFI28138.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 ComK protein F-box-like PF12937.2 EFI28139.1 - 0.0011 18.6 1.6 0.012 15.3 1.1 2.4 1 1 0 1 1 1 1 F-box-like Nop14 PF04147.7 EFI28139.1 - 0.003 15.5 15.0 0.0045 14.9 10.4 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 EFI28139.1 - 0.064 11.7 14.9 0.092 11.2 10.3 1.1 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 EFI28139.1 - 0.27 11.0 14.3 0.43 10.4 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.7 EFI28139.1 - 0.42 9.8 17.4 0.8 8.9 12.1 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EFI28139.1 - 2.8 5.8 14.2 4.3 5.2 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EFI28139.1 - 6 4.8 10.0 9.2 4.2 7.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ifi-6-16 PF06140.8 EFI28140.1 - 0.0069 16.1 2.5 0.014 15.2 1.7 1.5 1 0 0 1 1 1 1 Interferon-induced 6-16 family Rrn6 PF10214.4 EFI28140.1 - 0.027 12.5 0.4 0.034 12.2 0.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EI24 PF07264.6 EFI28140.1 - 0.1 12.0 6.5 1 8.7 0.3 2.3 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF2884 PF11101.3 EFI28140.1 - 0.16 11.3 0.7 0.23 10.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Ifi-6-16 PF06140.8 EFI28141.1 - 0.012 15.3 0.7 0.03 14.1 0.5 1.6 1 0 0 1 1 1 0 Interferon-induced 6-16 family Cytochrom_B562 PF07361.6 EFI28141.1 - 0.042 14.2 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b562 MIF4G PF02854.14 EFI28143.1 - 6e-47 159.7 11.3 6.9e-28 97.5 0.0 3.7 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 EFI28143.1 - 7e-23 81.2 8.7 7e-23 81.2 6.0 3.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 DUF3810 PF12725.2 EFI28143.1 - 0.43 9.4 9.0 0.06 12.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) Pkinase PF00069.20 EFI28144.1 - 2.7e-46 157.8 0.0 5.7e-46 156.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28144.1 - 2.4e-23 82.5 0.0 5.2e-19 68.3 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EFI28144.1 - 8.7e-08 32.1 0.0 0.0012 18.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EFI28144.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EFI28144.1 - 0.0014 17.9 0.1 0.0027 17.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EFI28144.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EFI28144.1 - 0.028 13.0 0.0 0.11 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EFI28144.1 - 0.057 12.5 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Ecdysteroid kinase CHZ PF09649.5 EFI28144.1 - 0.8 8.9 2.5 9.2 5.5 0.0 2.4 2 0 0 2 2 2 0 Histone chaperone domain CHZ RabGAP-TBC PF00566.13 EFI28145.1 - 1.2e-53 181.7 0.2 1.2e-53 181.7 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF2935 PF11155.3 EFI28145.1 - 0.02 14.9 1.0 0.044 13.8 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DivIVA PF05103.8 EFI28145.1 - 0.2 11.6 6.6 3.5 7.6 4.7 2.9 2 1 0 2 2 2 0 DivIVA protein DUF3492 PF11997.3 EFI28145.1 - 0.38 10.2 2.7 0.23 10.9 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3492) Scaffolding_pro PF11418.3 EFI28145.1 - 0.44 10.9 5.7 0.55 10.5 0.3 3.4 2 1 1 4 4 4 0 Phi29 scaffolding protein DUF2937 PF11157.3 EFI28145.1 - 1.2 8.4 4.1 1.4 8.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DivIC PF04977.10 EFI28145.1 - 1.4 8.4 11.1 0.43 10.0 0.7 3.0 2 1 1 3 3 3 0 Septum formation initiator APG6 PF04111.7 EFI28145.1 - 2.5 7.0 11.8 0.023 13.7 2.6 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EFI28145.1 - 6.4 6.3 12.1 0.26 10.8 4.0 1.9 2 0 0 2 2 2 0 IncA protein ABC1 PF03109.11 EFI28146.1 - 1.3e-32 112.2 0.0 2.7e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EFI28146.1 - 0.0002 20.7 0.1 0.001 18.4 0.0 2.0 2 0 0 2 2 2 1 RIO1 family GHMP_kinases_N PF00288.21 EFI28147.1 - 1.6e-13 50.5 0.5 3.8e-13 49.2 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EFI28147.1 - 6.6e-07 29.4 0.0 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal LSM PF01423.17 EFI28148.1 - 1.5e-07 30.8 0.1 2.1e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF1461 PF07314.6 EFI28148.1 - 0.096 12.4 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) RabGAP-TBC PF00566.13 EFI28151.1 - 5.6e-46 156.6 0.1 8.7e-46 156.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3731 PF12531.3 EFI28152.1 - 0.01 15.4 2.5 0.012 15.1 1.8 1.1 1 0 0 1 1 1 0 DNA-K related protein Lzipper-MIP1 PF14389.1 EFI28152.1 - 0.012 15.7 0.2 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 IMS PF00817.15 EFI28154.1 - 8.8e-47 158.6 0.0 2e-46 157.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EFI28154.1 - 2.8e-15 56.3 0.3 9.5e-15 54.6 0.2 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EFI28154.1 - 1.8e-06 27.6 0.0 3.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-C2HC_2 PF13913.1 EFI28154.1 - 0.11 12.2 0.3 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Papilloma_E5 PF03025.9 EFI28155.1 - 0.86 9.5 8.0 2.7 8.0 5.5 1.9 1 1 0 1 1 1 0 Papillomavirus E5 ATP_transf PF09830.4 EFI28156.1 - 6.4e-18 64.3 0.0 1e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EFI28156.1 - 0.0024 18.3 0.1 0.024 15.1 0.0 2.2 2 0 0 2 2 2 1 HIT domain Propep_M14 PF02244.11 EFI28157.1 - 0.065 12.9 1.0 0.22 11.2 0.7 2.0 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Prominin PF05478.6 EFI28157.1 - 2.1 5.7 9.2 4.3 4.7 6.4 1.4 1 1 0 1 1 1 0 Prominin 2-Hacid_dh_C PF02826.14 EFI28158.1 - 6.7e-51 171.9 0.0 8.9e-51 171.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EFI28158.1 - 6.6e-15 54.7 0.0 8.7e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EFI28158.1 - 0.00023 21.0 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EFI28158.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase zf-C2H2_4 PF13894.1 EFI28160.1 - 3.4e-10 39.5 4.6 0.00035 20.6 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EFI28160.1 - 7.4e-10 38.5 7.0 7.9e-05 22.7 0.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EFI28160.1 - 5.8e-08 32.6 9.5 6.6e-07 29.3 0.6 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EFI28160.1 - 0.00032 20.7 2.0 0.051 13.7 0.2 3.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EFI28160.1 - 0.0025 17.9 0.6 1.4 9.2 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EFI28160.1 - 0.12 12.6 2.0 0.51 10.6 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain TPR_11 PF13414.1 EFI28161.1 - 3.4e-16 58.6 7.7 1.1e-08 34.5 0.1 3.8 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EFI28161.1 - 1.7e-15 55.8 1.9 0.00017 21.0 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EFI28161.1 - 2.1e-12 45.9 3.8 0.0035 17.1 0.4 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 EFI28161.1 - 7e-12 44.8 0.0 1.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.1 EFI28161.1 - 2.7e-10 40.0 8.2 9.5e-07 28.6 0.3 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EFI28161.1 - 2.3e-09 36.3 0.3 0.00021 20.8 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EFI28161.1 - 0.00082 19.3 0.2 0.33 11.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EFI28161.1 - 0.001 18.6 7.1 0.11 12.3 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EFI28161.1 - 0.0013 19.0 1.9 67 4.2 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EFI28161.1 - 0.013 15.4 0.2 0.85 9.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EFI28161.1 - 0.017 15.8 4.4 0.079 13.6 0.2 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EFI28161.1 - 0.019 15.3 2.6 0.24 11.7 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Ycf1 PF05758.7 EFI28162.1 - 0.72 7.4 34.2 0.99 7.0 8.4 2.1 2 0 0 2 2 2 0 Ycf1 Pro_CA PF00484.14 EFI28164.1 - 1.3e-30 106.4 0.0 1.9e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF2407_C PF13373.1 EFI28165.1 - 3.8e-19 68.9 3.0 7.2e-19 68.0 1.1 2.1 2 1 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EFI28165.1 - 6.7e-10 39.0 0.0 6e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2855 PF11017.3 EFI28166.1 - 4.5e-66 223.1 0.0 6e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) An_peroxidase PF03098.10 EFI28166.1 - 0.089 11.1 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Animal haem peroxidase Sirohm_synth_M PF14824.1 EFI28166.1 - 0.67 8.9 2.1 12 4.9 0.1 2.9 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central FGE-sulfatase PF03781.11 EFI28167.1 - 6.4e-23 81.4 0.4 1.7e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EFI28167.1 - 2.5e-08 34.2 0.3 5.1e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 DinB superfamily DUF2275 PF10039.4 EFI28167.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Ank_2 PF12796.2 EFI28169.1 - 4.9e-24 84.4 0.4 1.5e-11 44.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EFI28169.1 - 5.2e-20 70.1 3.6 7.2e-08 31.8 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EFI28169.1 - 5.9e-16 56.9 0.3 0.0004 20.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EFI28169.1 - 1.9e-15 56.8 0.1 2.4e-07 31.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EFI28169.1 - 2.3e-15 56.2 1.5 4.5e-06 26.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Fe-S_biosyn PF01521.15 EFI28170.1 - 3.5e-13 49.4 0.0 5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MAD PF05557.8 EFI28171.1 - 0.24 9.4 15.3 0.34 8.9 10.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF218 PF02698.12 EFI28173.1 - 3e-07 30.0 0.0 4.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Herpes_UL7 PF01677.11 EFI28176.1 - 0.08 12.2 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus UL7 like Med12 PF09497.5 EFI28177.1 - 1.3e-24 85.9 0.1 4.3e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DASH_Dad2 PF08654.5 EFI28178.1 - 1.4e-09 37.8 0.3 2e-09 37.3 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Peptidase_C25 PF01364.13 EFI28178.1 - 0.15 10.9 0.0 0.18 10.7 0.0 1.0 1 0 0 1 1 1 0 Peptidase family C25 DUF1330 PF07045.6 EFI28179.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1330) GIY-YIG PF01541.19 EFI28179.1 - 0.067 13.5 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain HSP70 PF00012.15 EFI28180.1 - 3.9e-240 797.9 5.1 4.7e-240 797.6 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EFI28180.1 - 4e-21 74.9 1.3 2.3e-20 72.4 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 EFI28180.1 - 3.7e-05 22.8 0.0 7.2e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 StbA protein FtsA PF14450.1 EFI28180.1 - 0.0016 18.2 5.8 1.5 8.6 0.2 3.7 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 EFI28180.1 - 0.022 14.3 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EFI28180.1 - 0.036 12.9 2.8 1.8 7.2 0.0 3.2 4 0 0 4 4 4 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EFI28180.1 - 0.31 10.0 5.4 0.38 9.8 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase U3_assoc_6 PF08640.6 EFI28182.1 - 2.5e-26 91.2 5.2 6.5e-26 89.9 3.3 1.9 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EFI28182.1 - 0.00038 20.8 0.8 1.1 10.0 0.0 5.1 4 1 2 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EFI28182.1 - 0.0064 15.4 0.9 0.68 8.7 0.0 3.1 3 1 1 4 4 4 2 NRDE-2, necessary for RNA interference Suf PF05843.9 EFI28182.1 - 0.053 13.2 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EFI28182.1 - 0.062 13.5 0.0 11 6.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Med1 PF10744.4 EFI28184.1 - 0.0002 20.2 0.0 0.73 8.5 0.0 3.2 3 1 0 3 3 3 3 Mediator of RNA polymerase II transcription subunit 1 MS_channel PF00924.13 EFI28185.1 - 1.7e-18 66.7 1.8 2.9e-18 65.9 1.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EFI28185.1 - 3.9e-06 25.7 0.1 1.2e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EFI28185.1 - 2.9e-05 23.5 0.0 9.1e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EFI28185.1 - 0.00087 19.3 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EFI28185.1 - 0.0042 16.3 0.2 0.016 14.5 0.1 2.0 1 0 0 1 1 1 1 EF hand PBP1_TM PF14812.1 EFI28185.1 - 0.017 15.4 0.2 0.043 14.1 0.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DltD_C PF04914.7 EFI28185.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 DltD C-terminal region DUF1515 PF07439.6 EFI28186.1 - 0.076 12.8 0.5 0.15 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) tRNA-synt_1e PF01406.14 EFI28187.1 - 3e-112 374.6 0.0 5.4e-112 373.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EFI28187.1 - 1.6e-08 33.6 0.5 0.0007 18.3 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EFI28187.1 - 0.032 14.4 0.0 0.032 14.4 0.0 2.1 2 0 0 2 2 2 0 DALR domain Metallophos PF00149.23 EFI28188.1 - 0.0025 17.2 1.3 0.023 14.1 0.9 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SNF2_N PF00176.18 EFI28190.1 - 1.5e-56 191.3 0.0 2.2e-56 190.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EFI28190.1 - 1.1e-12 47.6 0.0 2.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EFI28190.1 - 6.6e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EFI28190.1 - 2.7e-05 24.0 0.0 8.7e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EFI28190.1 - 5.5e-05 22.1 0.0 0.00022 20.1 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.4 EFI28190.1 - 0.0015 18.6 3.0 0.73 10.0 0.2 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF2439) DUF2075 PF09848.4 EFI28190.1 - 0.02 13.9 0.0 0.04 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AChE_tetra PF08674.5 EFI28190.1 - 0.19 11.2 1.6 0.59 9.7 1.1 1.8 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain HTH_WhiA PF02650.9 EFI28191.1 - 0.022 15.1 0.3 0.21 11.9 0.1 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain ABC_tran PF00005.22 EFI28192.1 - 1.2e-33 116.3 0.0 2.1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EFI28192.1 - 4.7e-26 91.8 3.7 9.8e-26 90.7 2.5 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EFI28192.1 - 4.1e-07 30.2 0.1 0.00012 22.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EFI28192.1 - 3e-06 27.3 0.0 7.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EFI28192.1 - 2.6e-05 23.5 0.5 0.00046 19.4 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EFI28192.1 - 0.0017 17.8 0.1 0.0037 16.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.15 EFI28192.1 - 0.0074 15.9 0.1 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF258 PF03193.11 EFI28192.1 - 0.0076 15.4 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EFI28192.1 - 0.0081 16.3 0.2 0.042 13.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EFI28192.1 - 0.053 14.3 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EFI28192.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EFI28192.1 - 0.094 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EFI28192.1 - 0.097 12.5 0.5 1.8 8.5 0.3 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit G-alpha PF00503.15 EFI28192.1 - 0.15 10.7 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_15 PF13175.1 EFI28192.1 - 0.46 9.4 0.0 0.84 8.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RseC_MucC PF04246.7 EFI28192.1 - 3.2 7.3 6.4 18 4.9 0.6 2.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC COG5 PF10392.4 EFI28193.1 - 2.3e-07 30.8 0.0 3.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DSPc PF00782.15 EFI28194.1 - 2.5e-07 30.3 0.1 8.4e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EFI28194.1 - 0.00039 19.8 0.2 0.0075 15.6 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EFI28194.1 - 0.0062 15.9 0.1 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EFI28194.1 - 0.0078 16.2 0.0 0.019 15.0 0.0 1.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EFI28194.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TPR_11 PF13414.1 EFI28195.1 - 8.7e-37 124.6 33.3 1.3e-07 31.1 0.1 13.7 13 2 2 15 15 14 9 TPR repeat TPR_2 PF07719.12 EFI28195.1 - 1.2e-24 84.1 43.4 0.00067 19.3 0.0 18.6 21 0 0 21 21 20 5 Tetratricopeptide repeat TPR_16 PF13432.1 EFI28195.1 - 5.6e-23 81.0 64.8 3.1e-06 27.7 1.3 14.3 10 4 6 16 16 16 6 Tetratricopeptide repeat TPR_14 PF13428.1 EFI28195.1 - 6e-23 79.2 62.3 0.00034 20.9 0.1 18.5 13 6 7 20 20 17 4 Tetratricopeptide repeat TPR_1 PF00515.23 EFI28195.1 - 6e-23 79.4 24.1 0.0002 20.7 0.0 13.5 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_17 PF13431.1 EFI28195.1 - 6.9e-23 78.8 7.8 0.0026 17.7 0.0 10.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EFI28195.1 - 6.7e-20 71.2 45.6 4.1e-05 23.8 0.4 12.9 12 3 2 14 14 13 5 Tetratricopeptide repeat TPR_8 PF13181.1 EFI28195.1 - 7.5e-19 66.0 7.8 0.016 14.9 0.0 12.6 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_12 PF13424.1 EFI28195.1 - 8.3e-15 54.4 44.1 0.013 15.4 0.1 13.8 8 5 7 16 16 16 6 Tetratricopeptide repeat Apc3 PF12895.2 EFI28195.1 - 1.7e-11 44.1 11.8 0.12 12.5 0.0 8.4 7 1 1 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EFI28195.1 - 1.1e-06 28.4 22.1 0.44 10.4 0.0 8.1 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EFI28195.1 - 7.1e-06 25.4 27.8 0.028 14.1 0.1 10.6 11 1 2 13 13 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EFI28195.1 - 0.00027 21.1 29.4 2.2 8.8 0.1 12.3 13 0 0 13 13 11 1 Tetratricopeptide repeat RPN7 PF10602.4 EFI28195.1 - 0.00038 19.8 3.0 0.82 9.0 0.0 5.9 6 2 0 6 6 6 1 26S proteasome subunit RPN7 FAT PF02259.18 EFI28195.1 - 0.002 17.1 0.3 5.6 5.8 0.0 4.9 4 3 2 6 6 6 1 FAT domain Coatomer_WDAD PF04053.9 EFI28195.1 - 0.002 16.9 3.8 0.33 9.6 0.0 3.9 4 0 0 4 4 4 1 Coatomer WD associated region PPR_3 PF13812.1 EFI28195.1 - 0.0035 17.4 2.4 13 6.3 0.0 5.6 5 0 0 5 5 4 0 Pentatricopeptide repeat domain NARP1 PF12569.3 EFI28195.1 - 0.0065 15.2 5.5 7.4 5.1 0.0 4.3 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 HemY_N PF07219.8 EFI28195.1 - 0.0083 15.6 4.0 0.042 13.4 0.0 3.5 4 0 0 4 4 2 1 HemY protein N-terminus PPR PF01535.15 EFI28195.1 - 0.033 14.1 0.0 96 3.3 0.0 4.5 4 0 0 4 4 4 0 PPR repeat TPR_20 PF14561.1 EFI28195.1 - 0.041 13.9 0.2 0.041 13.9 0.1 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat V_ATPase_I PF01496.14 EFI28195.1 - 0.23 9.3 0.2 0.35 8.6 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Apc5 PF12862.2 EFI28195.1 - 0.46 10.3 6.6 4 7.3 0.0 4.6 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.1 EFI28195.1 - 1.4 8.8 9.8 5.1 7.0 0.0 5.0 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat eIF-3c_N PF05470.7 EFI28197.1 - 1.2e-175 585.0 25.7 2.8e-145 484.7 4.9 2.1 1 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EFI28197.1 - 4.6e-14 52.6 0.1 2.7e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain Myc_N PF01056.13 EFI28197.1 - 0.015 14.5 3.9 0.027 13.6 2.7 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 EFI28197.1 - 0.065 12.8 13.2 0.016 14.8 2.4 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region Peptidase_S7 PF00949.16 EFI28197.1 - 0.1 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease CENP-B_dimeris PF09026.5 EFI28197.1 - 0.16 12.2 13.1 0.36 11.0 9.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EFI28197.1 - 2.2 7.4 7.0 4 6.6 4.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2029 PF09594.5 EFI28198.1 - 0.064 12.7 5.1 0.12 11.8 3.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2029) CAP_GLY PF01302.20 EFI28199.1 - 8.2e-19 67.0 1.0 1.6e-18 66.1 0.7 1.5 1 0 0 1 1 1 1 CAP-Gly domain Tropomyosin_1 PF12718.2 EFI28199.1 - 4.4e-05 23.3 5.9 4.4e-05 23.3 4.1 7.7 2 2 5 8 8 8 3 Tropomyosin like TMF_DNA_bd PF12329.3 EFI28199.1 - 0.00024 20.8 12.1 0.00024 20.8 8.4 8.7 6 2 3 9 9 9 4 TATA element modulatory factor 1 DNA binding ERM PF00769.14 EFI28199.1 - 0.0018 17.8 1.0 0.0018 17.8 0.7 5.5 2 1 2 4 4 4 2 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EFI28199.1 - 0.052 12.7 34.1 0.41 9.7 0.6 4.9 1 1 4 6 6 6 0 Reovirus sigma C capsid protein zf-CCHC_4 PF14392.1 EFI28199.1 - 0.45 10.2 4.9 7.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_S13 PF00416.17 EFI28200.1 - 1.4e-41 141.2 1.3 1.7e-41 140.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EFI28200.1 - 0.003 16.1 0.0 0.0031 16.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EFI28200.1 - 0.045 13.8 0.1 0.12 12.4 0.1 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif PP28 PF10252.4 EFI28200.1 - 0.15 12.1 0.3 0.3 11.1 0.2 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Period_C PF12114.3 EFI28200.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Ribosomal_L34 PF00468.12 EFI28201.1 - 3.5e-18 64.9 8.1 5.8e-18 64.2 5.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 UBA PF00627.26 EFI28203.1 - 2.1e-25 87.8 1.0 2.1e-12 46.4 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EFI28203.1 - 1.2e-18 66.2 0.9 1.8e-18 65.6 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 EFI28203.1 - 1.4e-13 50.0 7.9 1.4e-13 50.0 5.5 1.8 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.3 EFI28203.1 - 4e-07 29.6 0.7 6.5e-07 28.9 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2999 PF11212.3 EFI28203.1 - 0.0016 18.4 1.2 0.041 13.9 0.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2999) Rad60-SLD_2 PF13881.1 EFI28203.1 - 0.0051 16.6 0.1 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EFI28203.1 - 0.0071 15.8 0.0 1.3 8.6 0.0 2.8 2 1 0 2 2 2 1 CUE domain UBA_3 PF09288.5 EFI28203.1 - 0.0091 15.5 0.0 0.28 10.8 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Ubiquitin_2 PF14560.1 EFI28203.1 - 0.016 15.4 0.2 0.028 14.6 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.4 EFI28203.1 - 0.034 14.3 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain WIYLD PF10440.4 EFI28203.1 - 0.055 13.4 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Rap1_C PF11626.3 EFI28203.1 - 0.098 12.5 0.0 6 6.8 0.0 2.6 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PRCC PF10253.4 EFI28203.1 - 0.21 12.2 9.9 0.61 10.7 1.8 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting PLA2_B PF01735.13 EFI28204.1 - 1.8e-97 326.5 0.0 2.3e-97 326.2 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF2207 PF09972.4 EFI28204.1 - 0.039 12.5 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Yippee-Mis18 PF03226.9 EFI28205.1 - 6.7e-11 42.0 0.0 1.1e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GPI-anchored PF10342.4 EFI28206.1 - 0.0002 21.7 0.0 0.00026 21.3 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NDUF_B12 PF08122.7 EFI28207.1 - 2.5e-22 78.3 0.3 3e-22 78.1 0.2 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family MipZ PF09140.6 EFI28207.1 - 0.018 14.1 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 ATPase MipZ Cation_ATPase_C PF00689.16 EFI28207.1 - 0.027 13.9 0.0 0.03 13.8 0.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus PHD PF00628.24 EFI28208.1 - 3.8e-11 42.4 9.8 6.3e-11 41.8 6.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EFI28208.1 - 0.0022 17.3 3.8 0.0049 16.1 2.7 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EFI28208.1 - 0.48 9.7 7.5 0.85 8.9 5.2 1.3 1 0 0 1 1 1 0 PHD-finger AAA_12 PF13087.1 EFI28211.1 - 7.5e-17 61.3 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EFI28211.1 - 5.2e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain LCM PF04072.9 EFI28212.1 - 6.3e-13 48.6 0.0 3.8e-11 42.8 0.0 2.5 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase APG6 PF04111.7 EFI28213.1 - 1.2 8.1 4.5 1.7 7.6 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PH PF00169.24 EFI28214.1 - 4.2e-08 33.3 0.0 9.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Pheromone PF08015.6 EFI28215.1 - 2.7e-05 24.8 0.9 0.00089 20.0 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pkinase PF00069.20 EFI28216.1 - 5.3e-45 153.5 0.0 3.2e-30 105.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28216.1 - 3e-30 105.1 0.0 3.8e-28 98.2 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI28216.1 - 0.02 13.8 0.0 0.24 10.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pheromone PF08015.6 EFI28217.1 - 1.2e-06 29.2 1.0 2.2e-05 25.1 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI28218.1 - 7e-07 29.9 1.7 2e-05 25.3 0.1 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pkinase PF00069.20 EFI28220.1 - 6.5e-55 186.0 0.0 1e-54 185.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28220.1 - 1e-21 77.2 0.0 1.6e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EFI28220.1 - 7.5e-05 22.5 0.0 7.5e-05 22.5 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EFI28220.1 - 0.0032 16.8 0.4 0.0059 15.9 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EFI28220.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase CASP_C PF08172.7 EFI28221.1 - 2.8e-69 232.9 1.4 2.8e-69 232.9 1.0 4.4 2 1 2 4 4 4 1 CASP C terminal DivIVA PF05103.8 EFI28221.1 - 0.047 13.7 67.3 0.067 13.2 8.0 6.4 3 2 3 6 6 6 0 DivIVA protein CENP-Q PF13094.1 EFI28221.1 - 0.064 13.2 0.2 0.064 13.2 0.1 4.6 2 1 2 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 EFI28221.1 - 3.8 7.3 33.3 6.2 6.6 0.1 5.2 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) DUF4618 PF15397.1 EFI28221.1 - 4.1 6.6 50.9 0.089 12.1 0.3 4.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) UXS1_N PF11803.3 EFI28221.1 - 7.1 6.4 9.4 0.98 9.2 1.0 3.7 4 1 0 4 4 4 0 UDP-glucuronate decarboxylase N-terminal GAS PF13851.1 EFI28221.1 - 8.7 5.4 72.8 0.87 8.7 6.4 4.8 4 1 1 5 5 5 0 Growth-arrest specific micro-tubule binding Methyltransf_26 PF13659.1 EFI28223.1 - 7.1e-10 38.9 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI28223.1 - 3.3e-09 37.3 0.0 4.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI28223.1 - 1.1e-07 31.5 0.0 8e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EFI28223.1 - 9.1e-05 21.7 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EFI28223.1 - 0.0002 20.7 0.1 0.00084 18.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EFI28223.1 - 0.0012 19.1 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EFI28223.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EFI28223.1 - 0.039 14.4 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.11 EFI28223.1 - 0.05 12.6 0.0 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase UPF0020 PF01170.13 EFI28223.1 - 0.054 13.0 0.0 0.36 10.3 0.0 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF4355 PF14265.1 EFI28224.1 - 0.0056 16.6 0.3 0.0066 16.3 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) DUF924 PF06041.6 EFI28224.1 - 0.094 12.4 0.2 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) Pyridox_oxidase PF01243.15 EFI28225.1 - 9.6e-13 47.9 0.0 7.3e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase CRAL_TRIO PF00650.15 EFI28227.1 - 1.9e-10 40.4 0.0 2.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain HALZ PF02183.13 EFI28227.1 - 0.007 16.0 1.8 0.013 15.2 1.3 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Spc97_Spc98 PF04130.8 EFI28230.1 - 2.6e-46 158.0 0.0 7e-46 156.6 0.0 1.6 1 1 0 1 1 1 1 Spc97 / Spc98 family Flu_PB2 PF00604.12 EFI28230.1 - 0.39 8.5 0.0 0.59 7.9 0.0 1.2 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 Peptidase_M36 PF02128.10 EFI28231.1 - 3.4e-91 305.9 0.1 4.2e-91 305.6 0.1 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EFI28231.1 - 6.1e-06 25.6 0.0 1.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EFI28231.1 - 0.011 15.8 0.0 0.043 13.8 0.0 2.1 1 0 0 1 1 1 0 Peptidase MA superfamily PepSY PF03413.14 EFI28231.1 - 0.042 14.4 0.0 0.093 13.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain RhoGEF PF00621.15 EFI28234.1 - 2.2e-33 115.6 0.2 3.6e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EFI28234.1 - 4.5e-31 107.4 0.0 1.1e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 EFI28234.1 - 1.2e-16 60.0 0.0 2.6e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 EFI28234.1 - 1.6e-08 34.4 0.1 2.9e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 CDC24 Calponin GCC2_GCC3 PF07699.8 EFI28235.1 - 2.9e-07 29.9 41.6 0.0009 18.7 6.4 4.9 3 2 2 5 5 5 3 GCC2 and GCC3 NCD3G PF07562.9 EFI28235.1 - 0.25 11.0 31.4 0.14 11.9 8.9 4.1 4 1 1 5 5 5 0 Nine Cysteines Domain of family 3 GPCR DUF3435 PF11917.3 EFI28236.1 - 0.094 11.4 3.1 0.14 10.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) SPATA25 PF15218.1 EFI28240.1 - 0.038 13.4 0.4 0.046 13.1 0.3 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 25 Gram_pos_anchor PF00746.16 EFI28241.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Gram positive anchor YesK PF14150.1 EFI28246.1 - 2.6 8.2 7.5 1.1 9.3 1.8 2.4 2 0 0 2 2 2 0 YesK-like protein SCPU PF05229.10 EFI28247.1 - 0.0029 17.7 0.3 0.0038 17.3 0.2 1.1 1 0 0 1 1 1 1 Spore Coat Protein U domain HSP70 PF00012.15 EFI28249.1 - 2e-05 22.7 0.0 3.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein DDR PF08841.5 EFI28249.1 - 0.028 13.2 0.2 6 5.5 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Peptidase_M22 PF00814.20 EFI28249.1 - 0.04 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family MreB_Mbl PF06723.8 EFI28249.1 - 0.12 10.9 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein Exo_endo_phos PF03372.18 EFI28250.1 - 1.1e-24 87.6 0.2 1.7e-24 87.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EFI28250.1 - 1.4e-17 62.8 7.1 2e-09 36.8 1.9 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EFI28250.1 - 1.6e-12 46.9 17.9 3.1e-07 30.0 2.5 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EFI28250.1 - 2.2e-08 33.0 7.4 0.063 13.3 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EFI28250.1 - 8.4e-08 31.2 4.6 0.25 11.6 0.3 4.8 4 0 0 4 4 4 2 Leucine rich repeat SPATA24 PF15175.1 EFI28250.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 LRR_6 PF13516.1 EFI28250.1 - 0.4 10.9 5.3 7 7.0 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat MBOAT_2 PF13813.1 EFI28251.1 - 2e-24 85.4 4.9 4.7e-24 84.2 3.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family YhhN PF07947.9 EFI28251.1 - 0.1 11.9 5.8 1.5 8.1 0.5 2.9 3 0 0 3 3 3 0 YhhN-like protein Ribosomal_L39 PF00832.15 EFI28255.1 - 4.8e-23 80.3 9.5 5.5e-23 80.1 6.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein REV PF00424.13 EFI28255.1 - 0.21 11.5 4.0 0.21 11.4 2.8 1.1 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF2316 PF10078.4 EFI28256.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Ank_2 PF12796.2 EFI28257.1 - 2.2e-68 226.6 13.3 1.1e-13 51.3 0.1 8.6 1 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EFI28257.1 - 8.1e-68 221.0 34.6 3.9e-06 26.4 0.0 16.4 16 0 0 16 16 16 16 Ankyrin repeat Ank_4 PF13637.1 EFI28257.1 - 1.1e-44 150.0 19.4 5.1e-07 30.0 0.1 10.9 3 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EFI28257.1 - 2.1e-42 142.1 31.4 1.4e-08 34.6 0.1 11.5 4 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EFI28257.1 - 3.7e-40 131.9 16.3 0.079 13.2 0.0 16.1 16 0 0 16 16 16 12 Ankyrin repeat SchA_CurD PF04486.7 EFI28257.1 - 1.4e-05 24.8 9.6 0.98 9.2 0.1 5.9 4 2 1 5 5 5 3 SchA/CurD like domain DUF348 PF03990.9 EFI28257.1 - 0.0049 16.4 0.4 0.94 9.1 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF348) NOG1 PF06858.9 EFI28261.1 - 3.9e-29 100.2 0.3 7.7e-29 99.3 0.2 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EFI28261.1 - 1.6e-26 91.7 0.8 4.4e-26 90.3 0.5 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EFI28261.1 - 2.6e-17 62.8 0.0 6.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EFI28261.1 - 8e-11 41.4 0.0 2.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EFI28261.1 - 9.9e-05 22.8 0.0 0.00026 21.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EFI28261.1 - 0.004 16.3 0.0 0.045 12.9 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EFI28261.1 - 0.02 14.7 1.0 2.7 7.7 0.0 3.0 2 1 1 3 3 3 0 Dynamin family AIG1 PF04548.11 EFI28261.1 - 0.071 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family RRN3 PF05327.6 EFI28261.1 - 0.75 7.8 3.9 1.2 7.2 2.7 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3049 PF11250.3 EFI28265.1 - 0.16 11.7 1.7 4.1 7.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3049) CDC73 PF05179.9 EFI28266.1 - 0.024 13.9 2.6 0.031 13.6 1.8 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family TRAP_alpha PF03896.11 EFI28266.1 - 0.069 12.1 4.1 0.086 11.8 2.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HisK_N PF09385.5 EFI28266.1 - 0.12 12.0 0.9 0.15 11.6 0.6 1.2 1 0 0 1 1 1 0 Histidine kinase N terminal Rrn6 PF10214.4 EFI28266.1 - 0.23 9.4 3.2 0.25 9.3 2.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.9 EFI28266.1 - 0.24 9.3 8.7 0.26 9.2 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Caldesmon PF02029.10 EFI28266.1 - 0.27 9.6 23.3 0.3 9.4 16.2 1.1 1 0 0 1 1 1 0 Caldesmon RdRP_4 PF02123.11 EFI28266.1 - 0.32 9.6 2.3 0.37 9.4 1.6 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase RNase_H2-Ydr279 PF09468.5 EFI28266.1 - 0.4 9.8 3.4 0.48 9.5 2.4 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF1510 PF07423.6 EFI28266.1 - 0.49 9.7 10.8 0.58 9.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 EFI28266.1 - 0.57 9.6 10.6 0.71 9.3 7.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ATP11 PF06644.6 EFI28266.1 - 0.65 9.4 5.0 0.83 9.0 3.4 1.1 1 0 0 1 1 1 0 ATP11 protein Endonuc_Holl PF10107.4 EFI28266.1 - 0.86 9.2 6.6 1.3 8.7 4.6 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF1266 PF06889.6 EFI28266.1 - 1.8 8.3 11.7 3.9 7.2 7.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Vfa1 PF08432.5 EFI28266.1 - 2.2 8.3 9.6 3.2 7.7 6.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 OmpH PF03938.9 EFI28266.1 - 2.3 8.1 10.0 3.1 7.7 6.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Adeno_VII PF03228.9 EFI28266.1 - 2.4 8.7 8.0 3.7 8.1 5.5 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII DDHD PF02862.12 EFI28266.1 - 3.8 7.2 8.9 5.1 6.8 6.1 1.1 1 0 0 1 1 1 0 DDHD domain MIP-T3 PF10243.4 EFI28266.1 - 6 5.2 21.5 7.5 4.8 14.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DinB PF05163.7 EFI28266.1 - 6 6.5 10.6 16 5.1 7.3 1.6 1 1 0 1 1 1 0 DinB family Ycf1 PF05758.7 EFI28266.1 - 6.9 4.2 7.7 6.7 4.2 5.3 1.0 1 0 0 1 1 1 0 Ycf1 YqfQ PF14181.1 EFI28266.1 - 7.2 6.6 7.1 9.5 6.2 4.9 1.3 1 0 0 1 1 1 0 YqfQ-like protein Macoilin PF09726.4 EFI28266.1 - 7.6 4.6 14.1 8.7 4.4 9.8 1.0 1 0 0 1 1 1 0 Transmembrane protein KfrA_N PF11740.3 EFI28266.1 - 8.9 6.7 23.6 13 6.2 16.4 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Spore_coat_CotO PF14153.1 EFI28266.1 - 9.5 5.6 16.7 14 5.0 11.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO rve PF00665.21 EFI28269.1 - 7.9e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain HTH_23 PF13384.1 EFI28269.1 - 0.0063 16.1 0.6 0.07 12.8 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain VD10_N PF08476.5 EFI28269.1 - 0.028 13.8 0.1 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Viral D10 N-terminal HTH_33 PF13592.1 EFI28269.1 - 0.069 12.6 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 Winged helix-turn helix HTH_11 PF08279.7 EFI28269.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 HTH domain PX PF00787.19 EFI28271.1 - 1.2e-24 86.2 0.0 1.3e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 PX domain DUF1286 PF06939.6 EFI28273.1 - 0.18 12.0 0.0 0.63 10.2 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1286) RNA_pol_3_Rpc31 PF11705.3 EFI28273.1 - 4.9 7.0 8.4 0.34 10.8 2.3 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1286 PF06939.6 EFI28274.1 - 0.18 12.0 0.0 0.63 10.2 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1286) RNA_pol_3_Rpc31 PF11705.3 EFI28274.1 - 4.9 7.0 8.4 0.34 10.8 2.3 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Alpha_kinase PF02816.13 EFI28277.1 - 5.2e-12 45.8 0.0 9.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family FYDLN_acid PF09538.5 EFI28277.1 - 0.16 12.5 0.5 0.37 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RPA_C PF08784.6 EFI28278.1 - 0.095 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal SDA1 PF05285.7 EFI28280.1 - 5.5 6.1 8.1 6.7 5.8 5.6 1.1 1 0 0 1 1 1 0 SDA1 CFEM PF05730.6 EFI28284.1 - 1.6e-07 31.0 21.3 7.7e-06 25.6 4.1 3.5 4 1 0 4 4 4 2 CFEM domain DUF740 PF05340.7 EFI28285.1 - 0.0025 16.2 9.6 0.0028 16.0 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF740) Plasmodium_Vir PF05795.6 EFI28285.1 - 3.4 6.7 6.7 4.8 6.2 4.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HMG14_17 PF01101.13 EFI28285.1 - 6.2 7.5 23.4 4.9 7.9 5.8 2.2 2 0 0 2 2 2 0 HMG14 and HMG17 BTV_NS2 PF04514.7 EFI28285.1 - 8.7 5.1 12.0 14 4.4 8.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AP_endonuc_2 PF01261.19 EFI28286.1 - 5.4e-20 71.5 0.0 8.4e-11 41.5 0.0 2.1 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel ATP-synt_Eps PF04627.8 EFI28288.1 - 1.5e-18 66.0 5.4 4.7e-18 64.4 2.0 2.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain TPR_12 PF13424.1 EFI28288.1 - 4.1e-17 61.8 14.9 0.0025 17.7 0.0 10.1 3 2 8 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 EFI28288.1 - 7.8e-10 38.2 8.8 0.055 13.1 0.0 8.0 2 1 5 9 9 9 3 TPR repeat NACHT PF05729.7 EFI28288.1 - 6.7e-08 32.3 0.0 2.6e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EFI28288.1 - 6.6e-05 22.9 0.0 0.00061 19.8 0.0 2.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.1 EFI28288.1 - 0.00064 19.7 0.3 85 3.7 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EFI28288.1 - 0.0021 18.5 23.1 16 6.4 0.0 10.0 9 2 2 11 11 8 0 Tetratricopeptide repeat TPR_7 PF13176.1 EFI28288.1 - 0.0033 17.1 10.5 4.8 7.2 0.0 7.6 9 0 0 9 9 8 1 Tetratricopeptide repeat NB-ARC PF00931.17 EFI28288.1 - 0.0036 16.2 0.0 0.0081 15.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain ArgK PF03308.11 EFI28288.1 - 0.0036 16.1 0.1 0.014 14.2 0.0 1.9 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EFI28288.1 - 0.0098 16.0 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 EFI28288.1 - 0.03 14.0 0.0 0.43 10.3 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EFI28288.1 - 0.04 14.1 0.1 1.1 9.4 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.11 EFI28289.1 - 3.3e-06 26.0 47.9 2.2e-05 23.3 19.3 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EFI28289.1 - 0.0038 16.9 6.0 0.018 14.8 0.4 3.5 3 0 0 3 3 3 1 MFS_1 like family DUF1146 PF06612.6 EFI28291.1 - 0.085 12.7 2.5 0.13 12.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) Hydrophobin PF01185.13 EFI28293.1 - 1.6e-13 50.8 11.3 3.4e-13 49.8 7.8 1.5 1 0 0 1 1 1 1 Fungal hydrophobin LDB19 PF13002.2 EFI28293.1 - 9.8e-06 25.1 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EFI28293.1 - 0.00017 21.4 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain F-box-like PF12937.2 EFI28293.1 - 0.00053 19.6 1.7 0.00053 19.6 1.1 2.0 2 0 0 2 2 2 1 F-box-like FTA4 PF13093.1 EFI28293.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Takusan PF04822.8 EFI28293.1 - 0.72 9.6 0.1 1.7 8.4 0.1 1.5 1 0 0 1 1 1 0 Takusan Syndecan PF01034.15 EFI28295.1 - 0.00052 19.6 0.1 0.00092 18.8 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain DUF1191 PF06697.7 EFI28295.1 - 0.0087 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) SlyX PF04102.7 EFI28295.1 - 0.34 11.3 5.5 0.37 11.2 0.1 2.4 2 0 0 2 2 2 0 SlyX Phage_GPO PF05929.6 EFI28295.1 - 0.41 9.8 2.9 0.68 9.1 2.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SOG2 PF10428.4 EFI28295.1 - 0.77 8.3 8.3 0.62 8.6 1.2 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Mnd1 PF03962.10 EFI28295.1 - 7.6 6.1 6.8 11 5.6 4.7 1.1 1 0 0 1 1 1 0 Mnd1 family Di19_C PF14571.1 EFI28296.1 - 0.02 15.1 0.2 0.023 15.0 0.2 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal MpPF26 PF07666.6 EFI28297.1 - 0.031 14.1 0.9 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 M penetrans paralogue family 26 DUF3529 PF12046.3 EFI28299.1 - 0.041 12.9 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) F-box-like PF12937.2 EFI28300.1 - 0.0011 18.6 0.1 0.0043 16.7 0.1 2.1 1 0 0 1 1 1 1 F-box-like Spore_coat_CotO PF14153.1 EFI28301.1 - 2.1 7.7 10.5 4 6.8 7.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO PAP_assoc PF03828.14 EFI28302.1 - 3e-17 62.3 0.9 8.2e-17 60.9 0.1 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EFI28302.1 - 2.2e-08 34.3 0.0 6e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain BssC_TutF PF08201.6 EFI28302.1 - 0.22 11.0 1.4 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 BssC/TutF protein Trypan_PARP PF05887.6 EFI28314.1 - 8.8 6.1 12.5 1.1 9.0 2.1 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF1191 PF06697.7 EFI28315.1 - 0.06 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Gram_pos_anchor PF00746.16 EFI28315.1 - 1 9.2 5.8 3.8 7.4 4.0 1.9 1 1 0 1 1 1 0 Gram positive anchor AAA_2 PF07724.9 EFI28317.1 - 3.4e-10 40.0 0.0 6.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EFI28317.1 - 1e-09 38.2 0.0 2.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EFI28317.1 - 5.9e-05 23.1 0.0 0.00072 19.5 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 EFI28317.1 - 6e-05 23.2 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.2 EFI28317.1 - 0.00085 19.6 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_22 PF13401.1 EFI28317.1 - 0.0043 17.2 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EFI28317.1 - 0.027 14.6 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EFI28317.1 - 0.028 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EFI28317.1 - 0.085 12.0 0.0 0.69 9.0 0.0 2.1 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 EFI28317.1 - 0.12 11.0 0.0 0.23 10.0 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain AAA_33 PF13671.1 EFI28317.1 - 0.19 11.6 0.0 0.88 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EFI28317.1 - 0.86 9.0 0.0 1.5 8.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain SH3_1 PF00018.23 EFI28319.1 - 1.7e-07 30.5 0.0 3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EFI28319.1 - 6.4e-06 25.6 0.0 1.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EFI28319.1 - 1.4e-05 24.5 0.0 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.1 EFI28319.1 - 0.028 14.4 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain HAMP PF00672.20 EFI28319.1 - 0.12 12.5 2.3 9.3 6.5 0.3 2.4 2 0 0 2 2 2 0 HAMP domain Glyco_hydro_85 PF03644.8 EFI28323.1 - 5.1e-63 213.0 0.0 7.2e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Memo PF01875.12 EFI28324.1 - 0.0097 14.7 0.2 4.2 6.1 0.0 2.4 2 0 0 2 2 2 2 Memo-like protein Proteasome PF00227.21 EFI28325.1 - 2.3e-51 173.8 0.1 2.8e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit NUDE_C PF04880.8 EFI28327.1 - 5.8 7.2 8.1 8.5 6.7 5.6 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Syja_N PF02383.13 EFI28328.1 - 8.1e-77 258.1 0.0 1e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EFI28328.1 - 8.7e-09 34.7 0.2 3.6e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Inositol phosphatase MFS_1 PF07690.11 EFI28330.1 - 1e-40 139.5 73.1 1.3e-18 66.8 13.0 4.1 4 0 0 4 4 4 4 Major Facilitator Superfamily WD40 PF00400.27 EFI28331.1 - 1.1e-47 158.2 22.4 9.8e-09 34.7 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EFI28331.1 - 2.1e-06 26.1 10.3 0.0013 17.0 0.3 4.7 2 2 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EFI28331.1 - 9.8e-05 21.2 2.1 0.21 10.2 0.0 4.6 2 2 2 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 EFI28331.1 - 0.00012 21.6 5.2 0.26 10.7 0.6 3.2 2 1 1 3 3 3 3 PQQ-like domain Tyr_Deacylase PF02580.11 EFI28332.1 - 1.5e-51 174.2 0.1 1.7e-51 174.0 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Tim54 PF11711.3 EFI28335.1 - 4.2e-72 242.8 2.7 1e-71 241.5 1.9 1.7 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Remorin_C PF03763.8 EFI28335.1 - 1.3 8.5 9.5 0.059 12.9 2.2 2.1 2 1 0 2 2 2 0 Remorin, C-terminal region Peptidase_M22 PF00814.20 EFI28336.1 - 0.0041 16.6 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family HSP70 PF00012.15 EFI28336.1 - 0.13 10.1 0.8 0.66 7.8 0.5 2.1 1 1 0 1 1 1 0 Hsp70 protein SKIP_SNW PF02731.10 EFI28337.1 - 2.3e-67 225.3 1.3 2.3e-67 225.3 0.9 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Spt5_N PF11942.3 EFI28337.1 - 7 7.3 24.1 0.37 11.4 6.4 3.1 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Abhydrolase_6 PF12697.2 EFI28338.1 - 1.1e-20 74.4 0.0 1.6e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EFI28338.1 - 7.2e-12 45.2 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EFI28338.1 - 4.4e-10 39.5 0.1 2.5e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EFI28338.1 - 0.0001 21.9 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 EFI28338.1 - 0.0036 16.7 0.0 0.42 10.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1100 PF06500.6 EFI28338.1 - 0.011 14.3 0.1 0.017 13.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.3 EFI28338.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF2048 PF09752.4 EFI28338.1 - 0.016 14.0 0.1 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) FSH1 PF03959.8 EFI28338.1 - 0.11 11.9 0.0 0.7 9.3 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF676 PF05057.9 EFI28338.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_2 PF01674.13 EFI28338.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) SIN1 PF05422.7 EFI28338.1 - 0.22 9.9 0.0 0.31 9.4 0.0 1.1 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Glyco_transf_22 PF03901.12 EFI28339.1 - 8.6e-59 199.5 12.7 1.1e-58 199.2 8.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_hydro_44 PF12891.2 EFI28340.1 - 1.5e-44 152.3 2.9 2.6e-44 151.5 2.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 44 Trp_syntA PF00290.15 EFI28341.1 - 1.1e-84 283.0 0.4 1.7e-84 282.4 0.3 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EFI28341.1 - 2.8e-43 148.3 0.1 4.1e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 EFI28341.1 - 5.8e-05 22.4 0.1 0.00014 21.2 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PA PF02225.17 EFI28341.1 - 0.0018 17.9 0.9 2.8 7.6 0.0 3.3 3 0 0 3 3 3 2 PA domain PcrB PF01884.12 EFI28341.1 - 0.037 13.2 0.2 0.099 11.8 0.1 1.6 2 0 0 2 2 2 0 PcrB family ThiG PF05690.9 EFI28341.1 - 0.091 11.8 0.2 0.35 9.9 0.1 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF3377 PF11857.3 EFI28342.1 - 0.76 9.4 6.0 0.9 9.2 4.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3377) Sulf_transp PF04143.9 EFI28343.1 - 4.1e-15 55.5 22.1 2.3e-11 43.5 1.5 4.2 4 1 1 5 5 5 2 Sulphur transport DUF4341 PF14241.1 EFI28343.1 - 2.4e-09 36.7 6.7 2.4e-09 36.7 4.6 3.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4341) DUF726 PF05277.7 EFI28344.1 - 8.7e-85 284.6 1.2 1.1e-84 284.2 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EFI28344.1 - 0.016 15.1 0.4 0.045 13.6 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 EFI28344.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase JmjC PF02373.17 EFI28345.1 - 7.9e-13 48.6 0.0 1.7e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 EFI28345.1 - 0.13 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Pyr_redox_3 PF13738.1 EFI28346.1 - 6.6e-15 55.7 0.0 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EFI28346.1 - 7.9e-11 40.8 0.1 4.9e-10 38.2 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EFI28346.1 - 9.7e-11 41.1 0.0 4.3e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Flag1_repress PF03614.8 EFI28346.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Sec63 PF02889.11 EFI28348.1 - 0.19 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Sec63 Brl domain FRG1 PF06229.7 EFI28349.1 - 5.7e-28 97.6 0.1 5.7e-28 97.6 0.1 1.5 2 0 0 2 2 2 1 FRG1-like family Fascin PF06268.8 EFI28349.1 - 0.00018 21.5 0.0 0.00044 20.3 0.0 1.8 2 0 0 2 2 2 1 Fascin domain DUF1754 PF08555.5 EFI28349.1 - 0.001 19.6 8.9 0.13 12.8 0.2 2.5 2 1 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) UCH PF00443.24 EFI28350.1 - 5.1e-17 61.8 0.2 6.1e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EFI28350.1 - 1.3e-12 47.7 0.1 1.7e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2296 PF10058.4 EFI28350.1 - 0.11 12.3 0.2 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) SAICAR_synt PF01259.13 EFI28351.1 - 0.028 13.5 0.3 0.044 12.8 0.2 1.3 1 1 0 1 1 1 0 SAICAR synthetase DUF2470 PF10615.4 EFI28351.1 - 0.075 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) RdRP PF05183.7 EFI28352.1 - 5.7e-154 514.0 0.0 8e-154 513.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Na_Ca_ex PF01699.19 EFI28352.1 - 5.9e-44 149.0 29.1 1.4e-23 83.0 6.5 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Spore_GerAC PF05504.6 EFI28352.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal PI3_PI4_kinase PF00454.22 EFI28353.1 - 1.6e-27 96.5 0.0 1.5e-26 93.3 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EFI28353.1 - 3e-20 72.1 0.0 8.4e-20 70.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF3161 PF11362.3 EFI28354.1 - 0.024 14.5 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Thioredoxin PF00085.15 EFI28356.1 - 4.3e-25 87.3 0.0 5.5e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EFI28356.1 - 2.3e-09 37.4 0.0 8.2e-09 35.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EFI28356.1 - 6.4e-08 32.6 0.0 5.5e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 EFI28356.1 - 7.7e-05 22.2 0.1 0.00044 19.8 0.0 1.8 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 EFI28356.1 - 0.0013 18.7 0.1 0.0036 17.2 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EFI28356.1 - 0.0032 17.1 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family ERp29_N PF07912.8 EFI28356.1 - 0.0098 15.8 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 EFI28356.1 - 0.01 15.3 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.1 EFI28356.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Pox_Ag35 PF03286.9 EFI28357.1 - 0.75 9.2 6.5 0.11 11.9 0.6 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein gag-asp_proteas PF13975.1 EFI28358.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease TPK_catalytic PF04263.11 EFI28359.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain DUF77 PF01910.12 EFI28360.1 - 1.8e-29 101.2 0.0 2.2e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EFI28360.1 - 0.026 14.6 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 YKOF-related Family PIF1 PF05970.9 EFI28361.1 - 1.1e-23 83.8 0.0 8.6e-23 80.8 0.0 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EFI28361.1 - 2.6e-07 30.4 0.0 6.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain HUN PF08729.5 EFI28361.1 - 0.0011 18.7 2.5 0.0044 16.8 1.7 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain AAA_19 PF13245.1 EFI28361.1 - 0.012 15.4 0.1 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain LRR_1 PF00560.28 EFI28364.1 - 0.077 13.0 0.2 8 6.9 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat Rrn6 PF10214.4 EFI28365.1 - 3.4e-07 28.7 6.5 1.1e-05 23.7 0.5 3.1 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor DUF1324 PF07038.6 EFI28365.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1324) Mito_carr PF00153.22 EFI28366.1 - 4.4e-47 157.7 2.6 1.1e-14 53.8 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DAGK_cat PF00781.19 EFI28368.1 - 1.4e-25 89.1 0.1 3.2e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.3 EFI28368.1 - 0.0001 21.0 0.0 0.00019 20.1 0.0 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nucleoporin_C PF03177.9 EFI28369.1 - 2e-58 198.3 3.4 3.1e-58 197.7 2.3 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EFI28369.1 - 3e-21 75.6 0.1 4.1e-21 75.2 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Methyltransf_11 PF08241.7 EFI28369.1 - 7.6e-14 51.9 0.0 2.1e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EFI28369.1 - 8.9e-07 28.7 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EFI28369.1 - 8e-06 26.2 0.0 2.4e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EFI28369.1 - 1.3e-05 25.2 0.0 3.8e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI28369.1 - 6.8e-05 23.4 0.0 0.00044 20.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EFI28369.1 - 0.0007 18.7 0.0 0.0017 17.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EFI28369.1 - 0.0099 15.4 0.0 0.091 12.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EFI28369.1 - 0.12 12.8 0.0 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain RPA_C PF08784.6 EFI28370.1 - 4.6e-15 55.8 0.2 1.1e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EFI28370.1 - 3.8e-06 26.6 0.1 6.7e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 EFI28370.1 - 0.0039 17.0 0.1 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti-codon PF01336.20 EFI28371.1 - 1.8e-07 30.9 0.1 3.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 EFI28371.1 - 3.2e-07 30.7 0.3 1.6e-06 28.4 0.2 2.1 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti_2 PF13742.1 EFI28371.1 - 3.8e-05 23.4 0.1 8.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF605 PF04652.11 EFI28371.1 - 0.25 10.6 14.1 0.3 10.4 9.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF390 PF04094.9 EFI28371.1 - 0.3 9.0 6.1 0.4 8.6 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF1589 PF07628.6 EFI28373.1 - 0.0093 15.8 1.1 0.012 15.4 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1589) DUF4537 PF15057.1 EFI28374.1 - 7.6e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.5 EFI28374.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding 53-BP1_Tudor PF09038.5 EFI28374.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Planc_extracel PF07595.7 EFI28375.1 - 1.1 9.0 3.6 1.6 8.5 2.5 1.3 1 0 0 1 1 1 0 Planctomycete extracellular FTHFS PF01268.14 EFI28376.1 - 7.6e-259 859.3 0.0 9.7e-259 859.0 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EFI28376.1 - 3.3e-68 227.8 0.3 8.5e-68 226.4 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EFI28376.1 - 7.6e-35 119.4 0.0 1.9e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SpoIIE PF07228.7 EFI28377.1 - 9.5e-11 41.7 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EFI28377.1 - 0.059 12.7 0.1 4.9 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.3 EFI28377.1 - 0.064 13.0 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III PP2C_2 PF13672.1 EFI28377.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Peptidase_M49 PF03571.10 EFI28378.1 - 2.1e-179 597.1 0.0 2.9e-165 550.5 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M49 Cas_Cmr5 PF09701.5 EFI28378.1 - 0.14 12.3 0.3 7.2 6.8 0.0 3.0 3 1 1 4 4 4 0 CRISPR-associated protein (Cas_Cmr5) TPR_12 PF13424.1 EFI28379.1 - 0.0035 17.2 7.7 0.61 10.0 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EFI28379.1 - 0.0052 16.6 0.4 15 5.7 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EFI28379.1 - 0.0055 16.3 0.3 0.098 12.3 0.1 2.8 2 0 0 2 2 2 1 TPR repeat DUF2225 PF09986.4 EFI28379.1 - 0.016 14.6 0.1 0.43 10.0 0.0 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_1 PF00515.23 EFI28379.1 - 0.042 13.4 0.6 5 6.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 EFI28379.1 - 1.1 9.9 6.5 11 6.8 0.5 3.5 3 0 0 3 3 3 0 Sel1 repeat TPR_16 PF13432.1 EFI28379.1 - 9.4 7.0 11.1 5.2 7.8 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat CLASP_N PF12348.3 EFI28381.1 - 5.8e-35 120.6 0.7 4e-10 39.4 0.0 5.2 5 0 0 5 5 5 4 CLASP N terminal HEAT PF02985.17 EFI28381.1 - 1.7e-13 49.3 11.1 0.0029 17.5 0.0 10.9 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 EFI28381.1 - 2.4e-13 50.1 20.3 0.0005 20.3 0.0 10.4 10 2 2 12 12 12 3 HEAT repeats HEAT_EZ PF13513.1 EFI28381.1 - 2.5e-05 24.6 20.6 0.57 10.7 0.1 9.3 10 1 0 10 10 9 2 HEAT-like repeat TAN PF11640.3 EFI28381.1 - 0.00012 21.8 1.1 0.075 12.7 0.1 4.9 7 0 0 7 7 7 1 Telomere-length maintenance and DNA damage repair Adaptin_N PF01602.15 EFI28381.1 - 0.00041 18.8 2.8 0.22 9.7 0.0 4.5 4 1 0 4 4 4 1 Adaptin N terminal region Nipped-B_C PF12830.2 EFI28381.1 - 0.00051 19.7 0.0 0.47 10.0 0.0 3.1 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus VHS PF00790.14 EFI28381.1 - 0.019 14.5 0.1 15 5.2 0.0 3.5 3 0 0 3 3 3 0 VHS domain Cnd1 PF12717.2 EFI28381.1 - 0.021 14.6 0.1 8.1 6.2 0.0 4.8 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF3077 PF11275.3 EFI28381.1 - 0.083 12.8 1.6 0.36 10.8 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3077) Arm PF00514.18 EFI28381.1 - 0.16 11.8 2.8 0.38 10.6 0.0 3.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 EFI28381.1 - 0.39 10.6 0.1 6.3 6.7 0.0 3.1 3 0 0 3 3 3 0 V-ATPase subunit H Apc5 PF12862.2 EFI28382.1 - 3.4e-08 33.2 1.6 1.1e-07 31.5 0.1 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 EFI28382.1 - 0.098 12.4 0.2 0.56 10.1 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat 2OG-FeII_Oxy_2 PF13532.1 EFI28383.1 - 1e-35 123.3 0.0 1.1e-32 113.4 0.0 2.2 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Ribosomal_S21e PF01249.13 EFI28383.1 - 4.4e-35 119.4 0.0 8e-35 118.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S21e RabGAP-TBC PF00566.13 EFI28384.1 - 1e-39 136.2 7.0 6.8e-38 130.2 1.1 2.2 1 1 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 EFI28384.1 - 9.2e-08 31.6 0.0 0.022 14.0 0.0 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3548) RhoGEF PF00621.15 EFI28387.1 - 1.7e-16 60.6 0.2 6.9e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain HSP70 PF00012.15 EFI28390.1 - 7.1e-274 909.3 4.1 8e-274 909.1 2.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EFI28390.1 - 7.8e-16 57.5 0.1 8e-15 54.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EFI28390.1 - 0.0018 17.9 0.0 0.0043 16.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EFI28390.1 - 0.0041 16.2 0.1 0.023 13.8 0.0 2.1 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase UCH_1 PF13423.1 EFI28391.1 - 1.5e-42 146.1 0.0 2.2e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EFI28391.1 - 4.3e-25 88.8 0.0 7.6e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.27 EFI28391.1 - 2.6e-07 30.2 6.2 0.14 12.0 0.0 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat UCH PF00443.24 EFI28391.1 - 0.00017 20.8 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3535 PF12054.3 EFI28392.1 - 6.5e-93 311.7 0.3 6.6e-92 308.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EFI28392.1 - 7.7e-75 251.4 0.0 1.1e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EFI28392.1 - 5.5e-13 48.5 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EFI28392.1 - 1.2e-09 37.4 13.5 0.6 10.3 0.1 9.3 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EFI28392.1 - 9.1e-05 22.7 0.0 0.51 10.7 0.0 3.1 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EFI28392.1 - 0.005 16.2 0.0 0.066 12.5 0.0 2.7 2 0 0 2 2 2 1 CLASP N terminal Dopey_N PF04118.9 EFI28392.1 - 0.014 14.1 0.1 0.061 12.0 0.0 2.0 3 0 0 3 3 3 0 Dopey, N-terminal DUF1546 PF07571.8 EFI28392.1 - 0.075 13.1 0.0 0.7 10.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EFI28392.1 - 0.087 13.3 16.5 45 4.6 0.2 7.9 7 2 2 9 9 9 0 HEAT-like repeat Cupin_8 PF13621.1 EFI28393.1 - 1.7e-07 31.0 0.1 1.9e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain SOG2 PF10428.4 EFI28395.1 - 3.7e-29 101.6 1.1 3.7e-29 101.6 0.8 2.3 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EFI28395.1 - 6.6e-05 22.4 0.0 0.00025 20.5 0.0 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) FYVE PF01363.16 EFI28396.1 - 9e-16 57.5 2.9 9e-16 57.5 2.0 2.0 2 0 0 2 2 2 1 FYVE zinc finger Rbsn PF11464.3 EFI28396.1 - 0.0006 19.3 2.0 0.0012 18.3 1.4 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.8 EFI28396.1 - 0.00075 19.2 2.4 0.00075 19.2 1.6 2.0 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type FYVE_2 PF02318.11 EFI28396.1 - 0.042 13.7 0.7 0.042 13.7 0.5 2.4 4 0 0 4 4 4 0 FYVE-type zinc finger Glu_synthase PF01645.12 EFI28399.1 - 1.8e-158 527.2 0.0 3.2e-158 526.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EFI28399.1 - 3.2e-133 443.8 0.0 4.4e-133 443.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EFI28399.1 - 5e-115 383.7 0.0 7.8e-115 383.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EFI28399.1 - 4.8e-69 231.4 2.8 9.2e-69 230.4 2.0 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EFI28399.1 - 4e-23 81.1 0.1 9.5e-23 79.9 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EFI28399.1 - 4e-19 69.2 0.0 1e-18 67.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EFI28399.1 - 8.2e-10 39.0 0.1 0.00034 20.7 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EFI28399.1 - 7.7e-08 32.2 0.0 3.1e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EFI28399.1 - 2.2e-07 31.1 0.1 0.00016 22.0 0.0 3.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EFI28399.1 - 7.1e-06 25.1 0.1 0.0011 17.9 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EFI28399.1 - 1.2e-05 23.9 1.0 3.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EFI28399.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EFI28399.1 - 0.0016 18.6 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EFI28399.1 - 0.004 16.0 0.0 0.004 16.0 0.0 2.8 4 0 0 4 4 4 1 FAD binding domain AdoHcyase_NAD PF00670.16 EFI28399.1 - 0.005 16.7 0.3 1.9 8.2 0.0 2.8 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.13 EFI28399.1 - 0.0051 15.7 0.8 0.028 13.2 0.6 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.18 EFI28399.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EFI28399.1 - 0.011 14.8 0.3 0.057 12.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EFI28399.1 - 0.019 14.0 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.16 EFI28399.1 - 0.035 13.6 0.1 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EFI28399.1 - 0.063 12.1 1.5 0.55 9.0 0.1 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 EFI28399.1 - 0.12 11.5 0.0 0.94 8.6 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EFI28399.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EFI28399.1 - 0.17 11.2 0.0 0.42 9.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EFI28399.1 - 0.23 11.0 0.0 0.58 9.7 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 EFI28399.1 - 0.32 9.1 0.0 4.3 5.4 0.0 2.6 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like Peptidase_M13_N PF05649.8 EFI28400.1 - 2.4e-90 303.3 0.0 3.6e-90 302.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EFI28400.1 - 1.4e-60 203.9 0.0 2.6e-60 203.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Mucin PF01456.12 EFI28400.1 - 0.0038 17.0 5.1 0.0065 16.2 3.6 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF4157 PF13699.1 EFI28400.1 - 0.13 12.4 0.4 22 5.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) 2OG-FeII_Oxy_2 PF13532.1 EFI28401.1 - 1.8e-09 37.7 0.0 1.9e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ORC5_C PF14630.1 EFI28402.1 - 1.1e-38 133.2 0.0 1.6e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AMP-binding PF00501.23 EFI28403.1 - 9.3e-83 277.9 0.0 1.3e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EFI28403.1 - 0.016 16.1 0.5 0.045 14.6 0.3 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF1785 PF08699.5 EFI28408.1 - 1e-06 27.9 0.0 2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Ank PF00023.25 EFI28408.1 - 0.048 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat Piwi PF02171.12 EFI28409.1 - 1.1e-54 185.5 0.0 9e-54 182.4 0.0 2.0 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 EFI28409.1 - 1.1e-10 40.9 0.0 2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Cyclin_N PF00134.18 EFI28411.1 - 6.3e-08 32.2 0.0 2.4e-07 30.3 0.0 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain SRP54 PF00448.17 EFI28412.1 - 2.1e-45 154.6 0.1 1.3e-44 152.0 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EFI28412.1 - 4.2e-45 154.2 0.4 1.1e-44 152.8 0.3 1.6 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 EFI28412.1 - 8.5e-08 32.1 0.0 2.5e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EFI28412.1 - 2.9e-07 30.0 0.0 8.3e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EFI28412.1 - 7.6e-05 21.6 0.1 0.00031 19.5 0.1 1.9 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 EFI28412.1 - 0.003 17.2 0.0 0.0095 15.6 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EFI28412.1 - 0.03 13.9 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EFI28412.1 - 0.034 14.2 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArsA_ATPase PF02374.10 EFI28412.1 - 0.052 12.5 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Anion-transporting ATPase Fer4_NifH PF00142.13 EFI28412.1 - 0.068 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family EndIII_4Fe-2S PF10576.4 EFI28413.1 - 0.018 15.2 0.3 0.039 14.1 0.2 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HOOK PF05622.7 EFI28414.1 - 2.3e-53 181.0 71.4 3.6e-52 177.1 32.0 3.2 1 1 1 2 2 2 2 HOOK protein TPR_MLP1_2 PF07926.7 EFI28414.1 - 0.00045 19.9 12.8 0.00045 19.9 8.8 7.0 4 2 2 7 7 7 2 TPR/MLP1/MLP2-like protein DUF3618 PF12277.3 EFI28414.1 - 0.031 14.3 6.1 0.3 11.1 0.6 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) Sec20 PF03908.8 EFI28414.1 - 0.33 10.6 13.7 0.14 11.8 2.3 3.7 3 1 0 3 3 3 0 Sec20 TraF_2 PF13729.1 EFI28414.1 - 1 8.1 6.4 1.8 7.2 1.0 2.8 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Reo_sigmaC PF04582.7 EFI28414.1 - 7.2 5.6 15.6 0.93 8.6 0.5 3.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein EI24 PF07264.6 EFI28415.1 - 5.6e-05 22.6 7.3 0.00018 21.0 5.0 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) RNA12 PF10443.4 EFI28416.1 - 7e-115 383.9 0.0 2.5e-114 382.1 0.0 1.8 1 1 0 1 1 1 1 RNA12 protein AAA_16 PF13191.1 EFI28416.1 - 2.4e-07 30.9 0.0 7.4e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EFI28416.1 - 1e-05 25.3 0.0 0.00034 20.3 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EFI28416.1 - 1.7e-05 24.9 0.1 8.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EFI28416.1 - 0.00027 19.9 0.0 0.00045 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EFI28416.1 - 0.00039 20.3 0.0 0.00095 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EFI28416.1 - 0.0006 19.6 0.0 0.0019 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EFI28416.1 - 0.0015 18.7 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RRM_1 PF00076.17 EFI28416.1 - 0.0029 17.2 0.0 0.0092 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF258 PF03193.11 EFI28416.1 - 0.0055 15.9 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EFI28416.1 - 0.0071 16.0 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EFI28416.1 - 0.009 16.3 0.0 0.032 14.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 EFI28416.1 - 0.012 15.2 0.0 0.05 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) RRM_5 PF13893.1 EFI28416.1 - 0.014 15.2 0.0 0.051 13.4 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_17 PF13207.1 EFI28416.1 - 0.016 16.0 0.0 0.1 13.4 0.0 2.4 2 0 0 2 2 1 0 AAA domain DUF3939 PF13075.1 EFI28416.1 - 0.025 14.2 0.0 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) Zeta_toxin PF06414.7 EFI28416.1 - 0.054 12.5 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 EFI28416.1 - 0.07 12.6 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EFI28416.1 - 0.077 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RRM_6 PF14259.1 EFI28416.1 - 0.081 12.9 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NACHT PF05729.7 EFI28416.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Metallophos PF00149.23 EFI28418.1 - 0.056 12.8 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase AAA PF00004.24 EFI28421.1 - 1.8e-41 141.4 0.0 3.7e-41 140.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EFI28421.1 - 5.5e-06 26.5 0.0 0.00042 20.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EFI28421.1 - 2.6e-05 23.9 0.0 0.00013 21.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EFI28421.1 - 0.00012 22.0 0.0 0.00038 20.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EFI28421.1 - 0.00014 21.8 0.0 0.00043 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EFI28421.1 - 0.00043 19.3 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EFI28421.1 - 0.0014 19.4 1.2 0.0029 18.4 0.1 2.3 2 1 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 EFI28421.1 - 0.0028 17.3 1.1 4.2 6.9 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 EFI28421.1 - 0.0047 16.6 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EFI28421.1 - 0.0049 15.9 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EFI28421.1 - 0.0091 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EFI28421.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EFI28421.1 - 0.013 15.7 0.7 0.049 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EFI28421.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EFI28421.1 - 0.023 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EFI28421.1 - 0.025 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EFI28421.1 - 0.027 13.8 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EFI28421.1 - 0.027 14.0 0.0 0.068 12.7 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EFI28421.1 - 0.04 13.0 0.0 0.099 11.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EFI28421.1 - 0.04 13.9 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 EFI28421.1 - 0.042 12.5 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 EFI28421.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EFI28421.1 - 0.093 12.1 0.1 0.33 10.3 0.0 1.9 1 1 0 2 2 2 0 AAA domain T2SE PF00437.15 EFI28421.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 EFI28421.1 - 0.13 11.7 0.0 0.34 10.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain BCDHK_Adom3 PF10436.4 EFI28422.1 - 1.8e-23 82.8 0.0 8.1e-13 48.2 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EFI28422.1 - 4.3e-15 55.3 0.0 2.4e-13 49.7 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EFI28422.1 - 8.7e-05 22.2 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 EFI28423.1 - 7.8e-36 123.5 0.7 9.7e-28 97.0 1.4 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28423.1 - 6.1e-12 45.1 0.8 1.1e-11 44.2 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EFI28423.1 - 0.0028 17.4 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EFI28423.1 - 0.14 11.6 0.2 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aa_trans PF01490.13 EFI28423.1 - 0.95 7.8 0.0 1.4 7.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein Pkinase PF00069.20 EFI28424.1 - 2.9e-39 134.7 0.0 8.8e-39 133.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28424.1 - 3.2e-39 134.5 0.0 5.4e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI28424.1 - 0.015 14.2 0.0 0.031 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 EFI28424.1 - 0.037 13.3 0.0 0.097 11.9 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF4567 PF15131.1 EFI28424.1 - 0.092 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) ATP-synt_Eps PF04627.8 EFI28425.1 - 0.33 10.5 4.0 0.97 9.0 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase epsilon chain Metal_resist PF13801.1 EFI28425.1 - 0.5 10.3 3.3 2.1 8.3 1.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance PRCC PF10253.4 EFI28426.1 - 1.5 9.4 7.7 0.41 11.3 0.8 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3484 PF11983.3 EFI28426.1 - 4.6 8.1 5.6 2 9.3 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Pkinase PF00069.20 EFI28427.1 - 3.9e-46 157.3 0.0 7.5e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28427.1 - 1.6e-42 145.3 0.0 7.3e-42 143.2 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase RasGEF PF00617.14 EFI28427.1 - 7.9e-13 48.5 0.3 3.4e-06 26.9 0.0 2.8 2 1 1 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 EFI28427.1 - 6e-09 35.9 0.1 2.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif Kinase-like PF14531.1 EFI28427.1 - 2.3e-05 23.5 0.0 4.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MFS_1 PF07690.11 EFI28428.1 - 2.1e-38 131.9 32.4 2.1e-38 131.9 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EFI28428.1 - 1.1e-06 27.5 10.6 1.1e-06 27.5 7.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EFI28428.1 - 1.1e-06 27.1 1.1 1.1e-06 27.1 0.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) RRM_1 PF00076.17 EFI28429.1 - 5.4e-26 90.0 0.0 2e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EFI28429.1 - 9.3e-22 75.2 0.0 2.7e-05 23.3 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 EFI28429.1 - 4.1e-18 65.1 0.0 4.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI28429.1 - 2.1e-14 53.1 0.0 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3517 PF12030.3 EFI28429.1 - 0.58 8.6 0.0 0.95 7.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Glyco_hydro_61 PF03443.9 EFI28431.1 - 1e-24 87.5 0.0 1.3e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 EFI28431.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Wzt C-terminal domain NYN PF01936.13 EFI28432.1 - 5.2e-35 120.8 0.0 9.2e-19 68.1 0.0 2.6 2 0 0 2 2 2 2 NYN domain eRF1_2 PF03464.10 EFI28435.1 - 1e-43 148.8 0.2 2.1e-43 147.8 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EFI28435.1 - 3.1e-40 136.9 0.4 6.9e-40 135.8 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EFI28435.1 - 7.1e-26 90.3 0.0 1.4e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 KorB PF08535.5 EFI28436.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 KorB domain Cmc1 PF08583.5 EFI28436.1 - 0.019 14.6 2.1 0.026 14.2 1.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like FTR PF01913.13 EFI28437.1 - 0.09 12.5 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Linker_histone PF00538.14 EFI28439.1 - 1.1e-14 54.2 0.0 2.9e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family EI24 PF07264.6 EFI28440.1 - 8e-34 116.9 15.1 1.2e-33 116.4 10.5 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) ADH_zinc_N_2 PF13602.1 EFI28441.1 - 9.1e-22 78.2 0.0 2.2e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EFI28441.1 - 1.5e-12 47.2 0.0 2.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EFI28441.1 - 0.00032 20.4 0.0 0.024 14.3 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 EFI28441.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) ELFV_dehydrog PF00208.16 EFI28441.1 - 0.096 12.2 0.7 0.31 10.5 0.3 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.1 EFI28442.1 - 2.2e-15 57.6 0.0 4.8e-15 56.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EFI28442.1 - 7.4e-06 25.5 0.1 0.00015 21.3 0.0 2.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EFI28442.1 - 0.015 15.0 0.0 0.05 13.3 0.0 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EFI28442.1 - 0.1 12.1 1.1 0.15 11.6 0.1 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PriCT_2 PF08707.6 EFI28443.1 - 0.02 14.7 0.1 52 3.8 0.0 4.0 3 1 1 4 4 4 0 Primase C terminal 2 (PriCT-2) NADase_NGA PF07461.6 EFI28443.1 - 1.4 7.4 11.6 11 4.5 0.1 4.5 2 2 5 7 7 7 0 Nicotine adenine dinucleotide glycohydrolase (NADase) UPF0081 PF03652.10 EFI28443.1 - 5.4 7.1 7.9 85 3.2 0.1 4.2 1 1 3 5 5 5 0 Uncharacterised protein family (UPF0081) DUF3318 PF11780.3 EFI28443.1 - 7.6 6.0 9.0 6.2 6.3 0.8 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3318) 2OG-FeII_Oxy_4 PF13661.1 EFI28444.1 - 1.9e-08 33.8 0.0 3.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EFI28444.1 - 9.2e-08 32.5 0.0 1.6e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EFI28444.1 - 0.0056 16.9 0.0 0.011 16.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF4058 PF13267.1 EFI28444.1 - 0.066 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) ALG3 PF05208.8 EFI28445.1 - 3.9e-123 411.3 17.9 4.5e-123 411.1 12.4 1.0 1 0 0 1 1 1 1 ALG3 protein GshA PF08886.6 EFI28448.1 - 0.091 11.0 0.0 0.1 10.8 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase HSP70 PF00012.15 EFI28449.1 - 8.1e-246 816.6 5.6 1e-245 816.3 3.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EFI28449.1 - 2.2e-17 62.6 0.2 3.3e-16 58.7 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein BcrAD_BadFG PF01869.15 EFI28449.1 - 0.0032 16.8 0.1 0.35 10.1 0.0 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family DUF1539 PF07560.6 EFI28449.1 - 0.03 14.2 0.1 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) FGGY_C PF02782.11 EFI28449.1 - 0.044 13.3 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EFI28449.1 - 0.048 12.7 0.2 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.6 EFI28449.1 - 0.072 12.0 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 StbA protein QRPTase_N PF02749.11 EFI28449.1 - 0.1 12.3 0.2 9.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Granin PF01271.12 EFI28450.1 - 0.21 10.2 2.5 0.26 9.9 1.7 1.0 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) CMD PF02627.15 EFI28454.1 - 8.5e-06 25.5 0.0 0.00027 20.7 0.0 2.5 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Ribonuclease_3 PF00636.21 EFI28455.1 - 2.5e-45 153.5 0.0 7.4e-23 81.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EFI28455.1 - 3.7e-31 107.7 0.0 1.3e-16 60.6 0.0 3.4 2 2 0 2 2 2 2 Ribonuclease-III-like DEAD PF00270.24 EFI28455.1 - 1.9e-16 60.0 0.0 3.6e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EFI28455.1 - 6.4e-14 51.5 0.0 3.1e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EFI28455.1 - 1.9e-13 50.6 0.0 3.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.9 EFI28455.1 - 1.3e-10 40.8 0.0 2.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain SNF2_N PF00176.18 EFI28455.1 - 3.5e-08 32.6 0.0 5.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3326 PF11805.3 EFI28456.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) PsbK PF02533.10 EFI28457.1 - 0.033 14.1 0.2 0.033 14.1 0.2 2.0 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component DUF2306 PF10067.4 EFI28457.1 - 0.91 9.6 3.9 2.8 8.1 0.0 3.2 3 1 1 4 4 4 0 Predicted membrane protein (DUF2306) COX17 PF05051.8 EFI28458.1 - 3.8e-18 65.2 4.1 5.5e-18 64.7 2.9 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) F-box PF00646.28 EFI28459.1 - 0.066 12.8 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 F-box domain Lactamase_B PF00753.22 EFI28460.1 - 6.3e-23 81.4 0.3 9.2e-23 80.8 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EFI28460.1 - 1.8e-05 24.4 0.7 2.7e-05 23.7 0.3 1.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EFI28460.1 - 0.096 12.3 0.2 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase superfamily domain HMG_box PF00505.14 EFI28461.1 - 4.1e-07 30.1 3.8 4.6e-06 26.8 2.6 2.2 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EFI28461.1 - 0.0028 17.9 0.6 0.0055 17.0 0.4 1.5 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.2 EFI28462.1 - 2.8e-07 30.1 0.0 1e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 F-box-like Hist_deacetyl PF00850.14 EFI28465.1 - 1.9e-75 254.0 0.1 2.6e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyoxalase_3 PF13468.1 EFI28467.1 - 5.4e-27 94.8 0.0 7.9e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Polysacc_lyase PF14099.1 EFI28468.1 - 0.04 13.5 0.0 0.13 11.9 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide lyase Methyltransf_23 PF13489.1 EFI28471.1 - 3.1e-10 40.0 0.0 5.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EFI28471.1 - 8e-10 39.0 0.1 1.1e-05 25.7 0.0 2.6 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EFI28471.1 - 3.1e-08 33.9 0.0 1.5e-06 28.5 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI28471.1 - 2e-07 31.5 0.0 4.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI28471.1 - 1.6e-06 27.8 0.0 2e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EFI28471.1 - 0.00012 21.3 0.0 0.00028 20.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EFI28471.1 - 0.00034 20.9 0.0 0.00073 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EFI28471.1 - 0.0022 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 EFI28471.1 - 0.0047 16.3 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EFI28471.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EFI28471.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_7 PF03492.10 EFI28471.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DREV PF05219.7 EFI28471.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase WD40 PF00400.27 EFI28472.1 - 2.5e-55 182.4 20.5 5.9e-12 44.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EFI28472.1 - 1.8e-08 34.3 0.2 0.00048 19.8 0.0 3.2 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EFI28472.1 - 0.00019 20.8 0.0 0.033 13.7 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3312 PF11768.3 EFI28472.1 - 0.04 12.1 0.0 0.13 10.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) Det1 PF09737.4 EFI28472.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Nbas_N PF15492.1 EFI28472.1 - 0.13 11.3 0.2 7.9 5.4 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EFI28472.1 - 0.16 9.7 0.0 0.53 8.0 0.0 1.3 1 1 0 1 1 1 0 IKI3 family Pheromone PF08015.6 EFI28474.1 - 5.8e-06 27.0 1.3 0.00032 21.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI28475.1 - 5.8e-06 27.0 1.3 0.00032 21.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI28477.1 - 5.8e-06 27.0 1.3 0.00032 21.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone Pheromone PF08015.6 EFI28478.1 - 5.8e-06 27.0 1.3 0.00032 21.4 0.0 2.0 1 1 1 2 2 2 2 Fungal mating-type pheromone p450 PF00067.17 EFI28479.1 - 1e-45 156.1 0.4 7.6e-24 84.0 0.0 3.3 3 0 0 3 3 3 3 Cytochrome P450 p450 PF00067.17 EFI28480.1 - 3.2e-10 39.1 0.1 3.8e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EFI28481.1 - 1.5e-57 195.1 0.0 1.7e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF929 PF06053.6 EFI28483.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF929) Dscam_C PF12355.3 EFI28488.1 - 0.52 10.5 2.9 0.62 10.3 2.0 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Tet_JBP PF12851.2 EFI28489.1 - 2.9e-06 26.6 0.0 4.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily IncA PF04156.9 EFI28489.1 - 0.24 10.9 2.2 0.44 10.1 1.5 1.3 1 0 0 1 1 1 0 IncA protein DUF446 PF04287.7 EFI28490.1 - 0.02 14.6 0.2 0.066 13.0 0.2 1.9 1 0 0 1 1 1 0 tRNA pseudouridine synthase C CAF1A PF12253.3 EFI28494.1 - 0.12 12.5 0.3 0.12 12.5 0.2 1.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A GAGA_bind PF06217.7 EFI28497.1 - 1 9.2 18.5 1.6 8.6 12.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family FTP PF07504.8 EFI28498.1 - 0.0014 18.0 0.5 0.0058 16.0 0.0 2.2 2 2 1 3 3 3 1 Fungalysin/Thermolysin Propeptide Motif LRR_6 PF13516.1 EFI28499.1 - 2.9e-08 32.9 2.6 1.6 9.0 0.1 6.4 9 0 0 9 9 9 3 Leucine Rich repeat eIF3_subunit PF08597.5 EFI28499.1 - 0.0017 17.9 10.1 0.0017 17.9 7.0 1.7 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit CENP-T PF15511.1 EFI28499.1 - 0.0034 16.6 19.0 0.0053 16.0 13.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T LRR_7 PF13504.1 EFI28499.1 - 0.043 14.0 5.0 54 4.6 0.0 6.3 8 0 0 8 8 8 0 Leucine rich repeat Mitofilin PF09731.4 EFI28499.1 - 0.24 10.0 9.2 0.33 9.5 6.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hex_IIIa PF02455.11 EFI28499.1 - 7 5.2 8.3 12 4.4 5.7 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) NOA36 PF06524.7 EFI28500.1 - 7.7 5.6 7.9 11 5.1 5.5 1.3 1 0 0 1 1 1 0 NOA36 protein Chromate_transp PF02417.10 EFI28502.1 - 2.7e-53 180.0 33.0 5e-29 101.0 9.9 2.2 2 0 0 2 2 2 2 Chromate transporter CcmH PF03918.9 EFI28502.1 - 0.4 9.6 3.7 1 8.3 0.1 2.7 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF1180 PF06679.7 EFI28503.1 - 0.089 12.6 13.3 0.018 14.9 6.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Transposase_21 PF02992.9 EFI28504.1 - 3.7e-08 32.7 0.0 9e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EFI28504.1 - 0.00043 19.7 0.1 0.0011 18.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RAM PF15320.1 EFI28506.1 - 0.12 12.6 2.8 0.12 12.6 1.9 1.0 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein SK_channel PF03530.9 EFI28508.1 - 0.015 15.1 0.3 0.023 14.5 0.0 1.4 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Mucin PF01456.12 EFI28510.1 - 8.1 6.2 11.3 9.7 5.9 7.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-MYND PF01753.13 EFI28513.1 - 2.2e-09 37.0 7.0 5.1e-09 35.8 4.9 1.6 1 0 0 1 1 1 1 MYND finger MCRS_N PF13325.1 EFI28513.1 - 0.06 12.8 0.1 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein DUF3966 PF13110.1 EFI28514.1 - 0.12 12.2 0.5 1.2 9.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3966) Skp1 PF01466.14 EFI28518.1 - 4.2e-08 33.1 0.0 6.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EFI28518.1 - 0.00049 20.1 0.0 0.00079 19.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain MCPVI PF02993.9 EFI28522.1 - 0.64 10.1 3.8 0.85 9.7 2.6 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Peptidase_C48 PF02902.14 EFI28528.1 - 0.00022 20.8 0.1 0.00046 19.8 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C5 PF00770.13 EFI28528.1 - 0.12 11.9 0.1 0.71 9.3 0.1 2.0 2 0 0 2 2 2 0 Adenovirus endoprotease DUF1996 PF09362.5 EFI28535.1 - 4.2e-70 236.0 0.0 5.7e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BTB PF00651.26 EFI28538.1 - 8.4e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Cir_N PF10197.4 EFI28539.1 - 0.023 14.7 0.0 0.023 14.7 0.0 2.9 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF1814 PF08843.6 EFI28541.1 - 0.0076 16.0 0.1 0.012 15.4 0.1 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) Runt PF00853.14 EFI28541.1 - 0.052 13.0 0.1 0.071 12.5 0.1 1.2 1 0 0 1 1 1 0 Runt domain zf-MYND PF01753.13 EFI28542.1 - 1.1e-08 34.8 7.2 1.9e-08 34.0 5.0 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EFI28542.1 - 0.05 12.8 0.8 0.11 11.8 0.5 1.6 1 0 0 1 1 1 0 Life-span regulatory factor DUF21 PF01595.15 EFI28543.1 - 3.7e-30 104.5 0.2 6.6e-30 103.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EFI28543.1 - 4.6e-06 26.3 0.1 0.079 12.7 0.0 2.9 3 0 0 3 3 3 2 CBS domain Pkinase PF00069.20 EFI28544.1 - 2.5e-17 62.8 0.0 2.9e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28544.1 - 2e-08 33.6 0.0 0.0061 15.6 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Epimerase PF01370.16 EFI28545.1 - 1e-22 80.7 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EFI28545.1 - 6.4e-16 57.8 0.0 1.2e-15 57.0 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EFI28545.1 - 2.1e-14 53.9 0.1 3.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EFI28545.1 - 2.6e-08 33.1 0.0 6.4e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EFI28545.1 - 1.9e-06 27.3 0.0 2.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EFI28545.1 - 0.00011 22.1 0.0 0.0011 18.9 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase zf-LITAF-like PF10601.4 EFI28546.1 - 2.4e-23 81.7 4.8 3.7e-23 81.1 3.4 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 EFI28546.1 - 0.0025 17.7 0.4 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 Zinc ribbon domain Cu2_monooxygen PF01082.15 EFI28546.1 - 0.013 15.4 0.1 0.028 14.4 0.0 1.5 1 1 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain zf-ISL3 PF14690.1 EFI28546.1 - 0.035 14.1 1.3 0.98 9.4 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.1 EFI28546.1 - 0.046 13.2 1.4 8.1 6.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain MTP18 PF10558.4 EFI28546.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) zf-ribbon_3 PF13248.1 EFI28546.1 - 0.17 11.1 2.5 2.1 7.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EFI28546.1 - 0.29 10.9 6.0 9.5 6.1 4.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon Ogr_Delta PF04606.7 EFI28546.1 - 0.82 9.3 4.5 1.5 8.5 0.1 2.5 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger NOB1_Zn_bind PF08772.6 EFI28546.1 - 3.6 7.4 6.8 9.8 6.0 0.1 2.5 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF605 PF04652.11 EFI28546.1 - 4.2 6.6 9.1 5 6.4 6.3 1.0 1 0 0 1 1 1 0 Vta1 like Asparaginase_2 PF01112.13 EFI28547.1 - 9.9e-56 188.7 0.0 5.5e-40 137.0 0.0 2.5 2 1 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.16 EFI28547.1 - 0.0082 14.6 0.3 0.055 11.9 0.4 1.9 2 0 0 2 2 2 1 Gamma-glutamyltranspeptidase TPR_12 PF13424.1 EFI28548.1 - 1.1e-32 111.8 18.7 0.028 14.3 0.0 14.4 3 3 11 15 15 15 10 Tetratricopeptide repeat TPR_11 PF13414.1 EFI28548.1 - 1.5e-32 111.0 7.6 0.00063 19.3 0.0 13.0 3 2 9 14 14 14 10 TPR repeat CHAT PF12770.2 EFI28548.1 - 1.2e-25 90.2 0.0 3e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.1 EFI28548.1 - 9.9e-21 72.9 47.8 0.0093 15.8 0.1 15.8 16 1 0 16 16 16 7 Tetratricopeptide repeat TPR_17 PF13431.1 EFI28548.1 - 4.1e-16 57.7 0.1 1.8 8.9 0.0 12.8 14 0 0 14 14 12 1 Tetratricopeptide repeat TPR_16 PF13432.1 EFI28548.1 - 1.2e-11 44.9 13.6 0.32 11.7 0.0 9.6 6 1 4 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 EFI28548.1 - 5.7e-11 41.4 26.3 1 9.4 0.0 14.1 16 0 0 16 16 16 2 Tetratricopeptide repeat TPR_1 PF00515.23 EFI28548.1 - 9e-08 31.4 22.1 0.9 9.2 0.0 12.4 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_8 PF13181.1 EFI28548.1 - 4.7e-06 26.0 0.0 7.9 6.5 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat MIT PF04212.13 EFI28548.1 - 7.2e-05 22.5 12.0 2.3 8.1 0.6 9.8 12 0 0 12 12 12 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 EFI28548.1 - 0.0033 17.1 9.0 41 4.3 0.1 10.2 13 0 0 13 13 13 0 Tetratricopeptide repeat Coleoptericin PF06286.6 EFI28548.1 - 0.0098 15.7 0.0 8 6.3 0.0 4.1 3 1 1 5 5 5 1 Coleoptericin Peptidase_C25 PF01364.13 EFI28548.1 - 0.46 9.3 0.0 0.76 8.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 DUF835 PF05763.7 EFI28550.1 - 0.083 12.4 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF835) zf-MYND PF01753.13 EFI28551.1 - 0.04 13.8 5.3 0.12 12.2 3.7 1.8 1 0 0 1 1 1 0 MYND finger Dimer_Tnp_hAT PF05699.9 EFI28552.1 - 0.07 12.7 0.2 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Ifi-6-16 PF06140.8 EFI28552.1 - 0.1 12.3 9.6 0.19 11.5 6.6 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family Phage_holin_2 PF04550.7 EFI28552.1 - 0.23 11.5 3.4 0.43 10.7 2.3 1.4 1 0 0 1 1 1 0 Phage holin family 2 ACP_syn_III PF08545.5 EFI28553.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.20 EFI28555.1 - 0.0035 17.2 1.5 0.065 13.1 1.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 EFI28555.1 - 0.12 11.4 0.2 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DHC_N1 PF08385.7 EFI28556.1 - 2.7e-192 640.2 1.8 2.7e-192 640.2 1.2 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 PMC2NT PF08066.7 EFI28556.1 - 0.064 13.5 1.5 15 5.9 0.1 3.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain HsbA PF12296.3 EFI28556.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.2 5 0 0 5 5 5 0 Hydrophobic surface binding protein A AATase PF07247.7 EFI28561.1 - 0.034 12.7 0.0 0.047 12.2 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase Glyco_transf_22 PF03901.12 EFI28562.1 - 0.0052 15.8 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SLAC1 PF03595.12 EFI28562.1 - 0.012 14.3 0.1 0.012 14.3 0.1 1.6 2 0 0 2 2 2 0 Voltage-dependent anion channel O-antigen_lig PF13425.1 EFI28562.1 - 0.031 14.2 0.2 0.031 14.2 0.2 1.7 2 0 0 2 2 2 0 O-antigen ligase like membrane protein MARVEL PF01284.18 EFI28562.1 - 0.12 12.1 4.0 0.093 12.5 0.5 2.0 2 0 0 2 2 2 0 Membrane-associating domain DUF1212 PF06738.7 EFI28562.1 - 0.24 10.8 0.1 0.24 10.8 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1212) RNase_PH PF01138.16 EFI28564.1 - 3.1e-10 40.4 0.0 4.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Med9 PF07544.8 EFI28565.1 - 4e-05 23.2 0.3 5.9e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_3 PF13758.1 EFI28565.1 - 0.036 13.8 0.2 0.052 13.3 0.2 1.3 1 0 0 1 1 1 0 Prefoldin subunit TPR_11 PF13414.1 EFI28566.1 - 2e-09 36.9 0.4 4.6e-09 35.7 0.3 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EFI28566.1 - 0.0068 16.2 1.9 0.58 10.2 1.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EFI28566.1 - 0.032 14.9 0.2 0.065 13.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EFI28566.1 - 0.039 13.9 0.2 1.7 8.6 0.3 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF4470 PF14737.1 EFI28567.1 - 9.4e-19 67.0 0.0 1.8e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.1 EFI28567.1 - 5.1e-10 38.8 2.1 8.1e-10 38.2 0.3 2.3 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EFI28567.1 - 3.5e-06 26.5 2.3 0.016 15.0 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EFI28567.1 - 0.0077 16.1 0.5 0.043 13.7 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EFI28567.1 - 0.6 9.8 7.0 1.6 8.4 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 EFI28570.1 - 5.3e-41 139.9 0.0 9e-41 139.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EFI28570.1 - 1.8e-27 95.0 0.1 8.2e-27 92.8 0.1 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EFI28570.1 - 5.9e-22 77.3 5.2 5.9e-22 77.3 3.6 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EFI28570.1 - 4.4e-07 30.1 1.3 7e-05 22.9 0.2 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EFI28570.1 - 7.7e-06 25.1 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EFI28570.1 - 8.4e-06 25.3 0.0 2.6e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EFI28570.1 - 2.1e-05 25.2 0.1 8.3e-05 23.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EFI28570.1 - 5e-05 23.3 0.2 0.0021 18.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EFI28570.1 - 5.8e-05 22.8 0.0 0.00019 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EFI28570.1 - 6e-05 22.9 0.2 0.00014 21.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EFI28570.1 - 0.00015 21.2 0.2 0.2 11.0 0.1 2.6 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EFI28570.1 - 0.00034 19.6 0.0 0.00092 18.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EFI28570.1 - 0.00048 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EFI28570.1 - 0.0011 17.7 0.0 0.0023 16.7 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 EFI28570.1 - 0.0031 17.1 0.0 0.0073 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EFI28570.1 - 0.0032 17.6 0.0 0.0096 16.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EFI28570.1 - 0.0044 17.3 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EFI28570.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) KaiC PF06745.8 EFI28570.1 - 0.0089 15.1 0.1 1.6 7.8 0.0 2.3 1 1 1 2 2 2 1 KaiC NACHT PF05729.7 EFI28570.1 - 0.013 15.1 0.0 0.34 10.5 0.0 2.5 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 EFI28570.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EFI28570.1 - 0.017 14.8 1.2 0.36 10.4 0.0 2.4 2 1 1 3 3 2 0 Archaeal ATPase Zeta_toxin PF06414.7 EFI28570.1 - 0.019 14.0 0.1 0.22 10.5 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EFI28570.1 - 0.025 14.3 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EFI28570.1 - 0.031 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.9 EFI28570.1 - 0.031 13.2 0.1 2.5 7.0 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 EFI28570.1 - 0.036 14.1 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EFI28570.1 - 0.047 12.9 1.9 0.066 12.4 0.1 2.2 2 1 0 2 2 2 0 PhoH-like protein Torsin PF06309.6 EFI28570.1 - 0.057 13.3 0.0 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.12 EFI28570.1 - 0.058 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EFI28570.1 - 0.12 11.8 0.0 0.5 9.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF4398 PF14346.1 EFI28570.1 - 0.6 10.1 6.1 0.078 13.0 1.1 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4398) BLVR PF06375.6 EFI28572.1 - 0.028 14.2 7.7 0.029 14.2 5.3 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) NST1 PF13945.1 EFI28572.1 - 0.22 11.5 6.2 0.21 11.6 4.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF1754 PF08555.5 EFI28572.1 - 0.43 11.2 14.2 0.57 10.8 9.8 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF3437 PF11919.3 EFI28574.1 - 3.5e-32 109.9 1.1 5.1e-31 106.2 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EFI28574.1 - 0.0033 17.3 0.4 0.07 13.2 0.1 3.6 2 0 0 2 2 2 1 HEAT repeat DUF1546 PF07571.8 EFI28574.1 - 0.0038 17.2 0.2 0.11 12.6 0.1 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) HEAT_2 PF13646.1 EFI28574.1 - 0.0039 17.4 2.6 0.035 14.3 0.0 3.7 5 0 0 5 5 5 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EFI28574.1 - 0.01 16.2 0.0 0.053 13.9 0.0 2.3 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EFI28574.1 - 0.031 14.1 1.4 7.8 6.2 0.1 4.0 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Translin PF01997.11 EFI28575.1 - 9.1e-27 93.9 0.1 2.2e-19 69.8 0.0 2.1 1 1 1 2 2 2 2 Translin family DUF3437 PF11919.3 EFI28576.1 - 1.2e-31 108.2 0.1 7.2e-31 105.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EFI28576.1 - 1.1e-08 34.4 6.0 0.011 15.7 0.1 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EFI28576.1 - 4.3e-06 26.9 0.8 0.00066 19.9 0.1 4.2 4 0 0 4 4 4 1 HEAT repeats XPA_C PF05181.7 EFI28577.1 - 5e-27 93.2 2.4 9.8e-27 92.3 1.6 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EFI28577.1 - 0.12 12.0 7.0 0.16 11.7 1.8 2.4 2 0 0 2 2 2 0 XPA protein N-terminal OrfB_Zn_ribbon PF07282.6 EFI28577.1 - 0.2 11.3 8.9 0.26 10.9 2.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EFI28577.1 - 2 7.7 5.5 16 4.8 0.0 2.5 2 1 0 2 2 2 0 zinc-ribbon domain PTH2 PF01981.11 EFI28579.1 - 2.3e-30 104.6 0.4 1.8e-29 101.7 0.3 2.0 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2760 PF10816.3 EFI28579.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) DUF2000 PF09391.5 EFI28579.1 - 0.13 11.9 0.0 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2000) Bromodomain PF00439.20 EFI28580.1 - 3.2e-41 139.1 0.1 8.8e-22 76.8 0.0 2.7 2 0 0 2 2 2 2 Bromodomain CENP-Q PF13094.1 EFI28580.1 - 0.044 13.8 4.9 0.1 12.6 3.4 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40 PF00400.27 EFI28581.1 - 1.1e-21 75.8 10.8 6e-09 35.4 0.3 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat UPF0270 PF06794.7 EFI28581.1 - 0.049 13.3 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) Ctr PF04145.10 EFI28582.1 - 3.6e-31 108.1 0.0 4.8e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family RWD PF05773.17 EFI28584.1 - 2.3e-15 56.4 1.4 7.7e-15 54.7 0.0 2.2 2 0 0 2 2 2 1 RWD domain IBR PF01485.16 EFI28584.1 - 2.8e-09 36.7 4.3 2.8e-09 36.7 3.0 3.2 3 1 0 3 3 3 2 IBR domain NinE PF05322.6 EFI28586.1 - 0.08 12.7 0.6 0.17 11.6 0.0 1.9 1 1 1 2 2 2 0 NINE Protein DUF4360 PF14273.1 EFI28588.1 - 6.3e-15 55.2 0.0 7.6e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MutS_V PF00488.16 EFI28589.1 - 3.3e-69 232.8 0.0 7.9e-69 231.6 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EFI28589.1 - 7e-30 104.3 3.3 7e-30 104.3 2.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EFI28589.1 - 7.6e-09 35.6 0.1 2.4e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EFI28589.1 - 0.024 14.6 0.1 0.23 11.5 0.1 2.6 1 1 0 1 1 1 0 MutS domain II Pkinase PF00069.20 EFI28591.1 - 7.8e-57 192.3 0.0 2.7e-56 190.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28591.1 - 2.7e-28 98.7 0.0 1.3e-19 70.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EFI28591.1 - 2.7e-05 23.2 0.1 0.00082 18.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EFI28591.1 - 0.0025 16.9 0.0 0.024 13.7 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EFI28591.1 - 0.0033 17.1 0.1 0.041 13.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family TFIIS_C PF01096.13 EFI28592.1 - 3.3e-18 65.0 11.3 4.6e-18 64.5 0.9 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EFI28592.1 - 1.3e-07 31.2 5.0 7e-06 25.6 0.3 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.1 EFI28592.1 - 1.2e-06 27.4 6.2 0.017 14.3 0.1 3.9 4 0 0 4 4 4 2 zinc-ribbon domain DZR PF12773.2 EFI28592.1 - 0.00015 21.4 8.7 0.0013 18.4 0.2 2.8 2 1 0 2 2 2 1 Double zinc ribbon Terminase_GpA PF05876.7 EFI28592.1 - 0.00025 19.5 0.7 0.00025 19.5 0.5 1.8 1 1 2 3 3 3 1 Phage terminase large subunit (GpA) IBR PF01485.16 EFI28592.1 - 0.00054 19.7 7.5 0.0089 15.8 0.2 2.5 2 1 0 2 2 2 1 IBR domain DUF2387 PF09526.5 EFI28592.1 - 0.00057 19.7 3.5 0.22 11.4 0.1 2.4 2 0 0 2 2 2 2 Probable metal-binding protein (DUF2387) Baculo_LEF5_C PF11792.3 EFI28592.1 - 0.0013 18.0 0.5 0.0013 18.0 0.4 2.6 3 0 0 3 3 2 1 Baculoviridae late expression factor 5 C-terminal domain PhnA_Zn_Ribbon PF08274.7 EFI28592.1 - 0.0017 18.1 10.9 0.11 12.2 0.0 3.3 2 2 1 3 3 3 1 PhnA Zinc-Ribbon PHD PF00628.24 EFI28592.1 - 0.0021 17.6 7.9 0.18 11.5 0.4 2.5 2 1 1 3 3 3 2 PHD-finger DUF523 PF04463.7 EFI28592.1 - 0.0025 17.6 0.2 0.0028 17.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) Zn_Tnp_IS1595 PF12760.2 EFI28592.1 - 0.0091 15.7 2.7 0.0091 15.7 1.9 3.3 2 2 1 3 3 3 1 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EFI28592.1 - 0.016 14.7 13.6 0.26 10.9 1.1 3.8 3 1 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.1 EFI28592.1 - 0.028 14.4 8.9 0.66 9.9 0.6 3.7 2 1 0 3 3 3 0 CpXC protein Cytochrom_CIII PF02085.11 EFI28592.1 - 0.028 14.4 8.2 0.049 13.7 5.0 1.9 1 1 1 2 2 2 0 Class III cytochrome C family DUF164 PF02591.10 EFI28592.1 - 0.034 13.9 8.1 3.5 7.5 0.1 3.8 3 1 1 4 4 4 0 Putative zinc ribbon domain UPF0547 PF10571.4 EFI28592.1 - 0.041 13.5 12.2 0.19 11.4 0.1 3.2 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 Cytochrome_C554 PF13435.1 EFI28592.1 - 0.048 13.7 6.9 0.098 12.7 4.9 1.4 1 1 0 1 1 1 0 Cytochrome c554 and c-prime zinc-ribbons_6 PF07191.7 EFI28592.1 - 0.05 13.3 5.5 0.74 9.6 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2296 PF10058.4 EFI28592.1 - 0.064 13.0 5.9 17 5.2 0.0 4.0 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) Zn-ribbon_8 PF09723.5 EFI28592.1 - 0.07 13.1 10.9 10 6.1 0.1 4.0 3 1 1 4 4 4 0 Zinc ribbon domain zf-RING_3 PF14369.1 EFI28592.1 - 0.078 12.9 7.3 25 4.9 0.0 3.9 3 1 1 4 4 4 0 zinc-finger zinc_ribbon_4 PF13717.1 EFI28592.1 - 0.084 12.5 13.9 0.74 9.5 1.5 3.9 3 1 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EFI28592.1 - 0.15 11.7 8.7 0.44 10.2 0.2 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 EFI28592.1 - 0.15 12.3 8.2 0.83 10.0 0.1 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-C4pol PF14260.1 EFI28592.1 - 0.16 11.9 3.7 1.8 8.5 1.2 2.4 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DNA_ligase_ZBD PF03119.11 EFI28592.1 - 0.19 11.4 6.9 1.7 8.3 0.2 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DNA_RNApol_7kD PF03604.8 EFI28592.1 - 0.24 10.8 11.1 1 8.8 1.0 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF35_N PF12172.3 EFI28592.1 - 0.28 11.1 7.9 0.59 10.1 0.0 3.0 4 0 0 4 4 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Cytochrome_C7 PF14522.1 EFI28592.1 - 0.5 10.0 9.7 53 3.5 6.9 2.4 1 1 0 1 1 1 0 Cytochrome c7 zinc_ribbon_2 PF13240.1 EFI28592.1 - 0.53 9.8 17.8 3 7.4 4.5 3.7 3 1 0 3 3 3 0 zinc-ribbon domain DUF1451 PF07295.6 EFI28592.1 - 0.56 9.9 8.1 0.56 9.9 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) Zn_ribbon_recom PF13408.1 EFI28592.1 - 0.59 10.4 7.2 10 6.4 1.1 2.8 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain Rpr2 PF04032.11 EFI28592.1 - 0.88 9.4 9.1 2.1 8.2 0.4 3.3 2 2 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HypA PF01155.14 EFI28592.1 - 0.92 9.2 7.5 4.1 7.1 2.4 2.6 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C4_Topoisom PF01396.14 EFI28592.1 - 0.96 9.0 12.2 1.5 8.3 1.4 3.9 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Spt4 PF06093.8 EFI28592.1 - 1.5 8.7 5.4 2.8 7.8 0.2 2.6 2 2 0 2 2 2 0 Spt4/RpoE2 zinc finger A2L_zn_ribbon PF08792.5 EFI28592.1 - 1.7 8.2 10.5 4.1 6.9 0.1 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain Auto_anti-p27 PF06677.7 EFI28592.1 - 2.8 7.7 13.4 4.7 7.0 1.6 3.2 3 1 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TF_Zn_Ribbon PF08271.7 EFI28592.1 - 3 7.2 13.7 0.47 9.8 1.0 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding Cys_rich_CPCC PF14206.1 EFI28592.1 - 3.4 7.2 7.0 2.7 7.5 0.1 2.4 2 1 0 2 2 2 0 Cysteine-rich CPCC Nudix_N_2 PF14803.1 EFI28592.1 - 3.6 7.3 13.4 13 5.5 3.2 3.9 3 1 0 3 3 3 0 Nudix N-terminal Prok-RING_1 PF14446.1 EFI28592.1 - 4.1 7.2 10.0 2 8.2 1.6 3.2 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 GFA PF04828.9 EFI28592.1 - 4.7 7.2 8.7 9.4 6.2 0.1 2.8 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-DNA_Pol PF08996.5 EFI28592.1 - 4.8 6.5 7.2 0.53 9.6 0.3 2.3 2 1 0 2 2 2 0 DNA Polymerase alpha zinc finger FdhE PF04216.7 EFI28592.1 - 6.3 6.4 8.6 0.29 10.7 0.3 2.2 2 1 0 2 2 2 0 Protein involved in formate dehydrogenase formation RecR PF02132.10 EFI28592.1 - 6.6 6.2 10.8 14 5.2 0.3 3.5 4 0 0 4 4 3 0 RecR protein TIP120 PF08623.5 EFI28594.1 - 2.9e-50 170.1 0.2 2.9e-50 170.1 0.1 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EFI28594.1 - 3.2e-18 65.8 14.9 0.00019 21.6 0.5 9.5 7 3 2 10 10 10 5 HEAT repeats HEAT PF02985.17 EFI28594.1 - 4.1e-18 63.7 20.2 0.0026 17.6 0.0 12.3 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 EFI28594.1 - 3.4e-16 59.1 24.6 0.0097 16.3 0.1 12.5 11 2 2 13 13 13 5 HEAT-like repeat Cnd1 PF12717.2 EFI28594.1 - 7.7e-11 42.1 1.9 0.1 12.4 0.0 5.7 4 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EFI28594.1 - 4.8e-08 32.6 5.5 0.11 11.8 0.0 7.0 6 2 2 9 9 9 2 CLASP N terminal UME PF08064.8 EFI28594.1 - 1.9e-07 30.9 1.0 0.0037 17.1 0.0 4.3 4 0 0 4 4 4 1 UME (NUC010) domain ParcG PF10274.4 EFI28594.1 - 7.4e-06 25.9 3.2 0.88 9.4 0.0 5.5 6 0 0 6 6 6 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 EFI28594.1 - 1.5e-05 25.3 1.1 12 6.4 0.0 6.9 7 0 0 7 7 7 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EFI28594.1 - 0.00046 18.6 6.8 3.4 5.8 0.0 5.3 5 0 0 5 5 5 2 Adaptin N terminal region DUF2435 PF10363.4 EFI28594.1 - 0.0082 16.0 0.5 0.41 10.5 0.0 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF3385 PF11865.3 EFI28594.1 - 0.0091 15.9 1.1 0.42 10.5 0.0 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) V-ATPase_H_C PF11698.3 EFI28594.1 - 0.03 14.2 0.1 3.9 7.4 0.1 4.0 4 0 0 4 4 3 0 V-ATPase subunit H MMS19_C PF12460.3 EFI28594.1 - 1.3 7.6 31.6 0.75 8.4 0.6 6.4 6 1 1 7 7 7 0 RNAPII transcription regulator C-terminal DUF2457 PF10446.4 EFI28594.1 - 1.7 7.3 9.8 2.7 6.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EFI28594.1 - 2.6 7.5 7.0 5.6 6.4 4.8 1.5 1 0 0 1 1 1 0 Nucleoplasmin RRM_1 PF00076.17 EFI28595.1 - 3.5e-42 141.8 0.2 2.7e-20 71.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI28595.1 - 6e-32 109.4 0.1 3.9e-15 55.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI28595.1 - 1.3e-25 88.9 0.1 3.8e-10 39.4 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EFI28595.1 - 1.4e-22 79.6 0.2 3.4e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EFI28595.1 - 2.7e-05 23.9 0.2 0.0012 18.6 0.0 2.7 2 1 0 2 2 2 1 RNA binding motif Ribonuc_L-PSP PF01042.16 EFI28596.1 - 1.1e-35 121.9 0.3 1.3e-35 121.7 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP C2 PF00168.25 EFI28597.1 - 2.4e-16 59.3 0.6 3.3e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain DUF1469 PF07332.6 EFI28597.1 - 0.0092 15.7 0.1 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) IncA PF04156.9 EFI28597.1 - 0.4 10.2 2.9 0.63 9.6 0.0 2.2 2 0 0 2 2 2 0 IncA protein DUF866 PF05907.8 EFI28598.1 - 1.9 7.9 5.3 0.95 8.9 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) RNase_H2-Ydr279 PF09468.5 EFI28599.1 - 0.27 10.4 2.1 0.49 9.5 1.4 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_C37 PF05416.7 EFI28599.1 - 1.6 6.9 1.9 2.8 6.1 1.3 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase 2-Hacid_dh_C PF02826.14 EFI28600.1 - 1.6e-56 190.2 0.0 1.4e-54 183.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EFI28600.1 - 4.2e-09 35.9 0.0 9.9e-09 34.7 0.0 1.6 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EFI28600.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EFI28600.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain PC_rep PF01851.17 EFI28601.1 - 9.9e-34 113.6 26.0 5.2e-09 35.8 0.0 9.5 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EFI28601.1 - 9.3e-24 83.5 7.8 8.6e-11 41.9 0.0 4.7 2 1 4 6 6 6 5 HEAT repeats HEAT PF02985.17 EFI28601.1 - 9.8e-07 28.3 0.4 3 8.1 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EFI28601.1 - 1.1e-05 25.7 8.4 0.011 16.1 0.0 5.1 4 0 0 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.11 EFI28601.1 - 6.9 7.4 7.1 1.9e+02 3.0 0.0 5.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Crp PF00325.15 EFI28603.1 - 0.0081 15.6 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory proteins, crp family Myosin_N PF02736.14 EFI28603.1 - 0.19 11.4 2.9 1.2 8.8 0.2 2.7 2 1 0 2 2 2 0 Myosin N-terminal SH3-like domain DIE2_ALG10 PF04922.7 EFI28605.1 - 9.6e-84 281.5 6.8 1.5e-83 280.9 4.7 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family CstA PF02554.9 EFI28605.1 - 0.062 11.9 5.8 1.3 7.6 3.6 2.4 2 0 0 2 2 2 0 Carbon starvation protein CstA Filament PF00038.16 EFI28606.1 - 0.00027 20.5 12.3 0.00043 19.8 8.5 1.2 1 0 0 1 1 1 1 Intermediate filament protein FMO-like PF00743.14 EFI28607.1 - 2.1e-33 115.3 0.0 1e-22 80.0 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EFI28607.1 - 3.1e-15 56.7 0.0 5.5e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EFI28607.1 - 2e-05 24.3 0.2 0.0024 17.6 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EFI28607.1 - 3.8e-05 22.7 0.3 0.0032 16.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EFI28607.1 - 0.00021 21.2 0.0 0.036 13.9 0.0 2.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EFI28607.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EFI28607.1 - 0.09 11.6 0.2 2.2 7.1 0.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase RNase_T PF00929.19 EFI28608.1 - 1.2e-07 32.1 0.0 1.6e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Indigoidine_A PF04227.7 EFI28609.1 - 2.1e-109 365.2 0.0 6.6e-109 363.6 0.0 1.8 1 1 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EFI28609.1 - 5.6e-17 61.8 4.1 2e-10 40.3 0.3 3.3 2 1 1 3 3 3 2 pfkB family carbohydrate kinase Antimicrobial12 PF08107.6 EFI28609.1 - 0.06 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Pleurocidin family GATase_4 PF13230.1 EFI28610.1 - 1.9e-20 72.6 0.0 3.5e-20 71.8 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EFI28610.1 - 8.7e-09 35.4 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EFI28610.1 - 1.5e-08 33.8 0.0 7e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II RNA_pol_L PF01193.19 EFI28610.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain PGM_PMM_I PF02878.11 EFI28611.1 - 8.7e-19 67.3 0.1 3e-08 33.2 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EFI28611.1 - 4.9e-15 55.7 0.0 2.2e-14 53.6 0.0 2.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EFI28611.1 - 2.6e-10 40.1 0.1 8.8e-10 38.4 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EFI28611.1 - 0.025 14.6 0.1 0.056 13.4 0.0 1.7 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ATP1G1_PLM_MAT8 PF02038.11 EFI28611.1 - 0.033 13.1 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Herpes_gE PF02480.11 EFI28612.1 - 0.015 13.6 0.0 0.059 11.6 0.0 2.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 EFI28612.1 - 0.04 13.7 0.0 0.04 13.7 0.0 7.2 4 2 2 6 6 6 0 Protein of unknown function (DUF1180) DUF302 PF03625.9 EFI28612.1 - 0.18 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF302 DUF3681 PF12442.3 EFI28612.1 - 0.86 9.8 6.5 0.84 9.8 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) DUF1921 PF09081.5 EFI28613.1 - 0.019 14.9 1.6 0.034 14.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) DNA_pol_B PF00136.16 EFI28614.1 - 7.3e-89 298.6 0.0 1e-88 298.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EFI28614.1 - 3.9e-18 65.4 0.0 6.7e-10 38.3 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EFI28614.1 - 1.2e-12 47.6 3.5 2.6e-12 46.5 2.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta WD40 PF00400.27 EFI28615.1 - 2.7e-07 30.2 15.7 0.0044 16.8 0.5 5.7 6 1 0 6 6 6 3 WD domain, G-beta repeat bZIP_1 PF00170.16 EFI28616.1 - 0.0011 18.8 6.5 0.0027 17.6 4.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor Apc4 PF12896.2 EFI28617.1 - 3.2e-40 137.7 0.0 5.8e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PD40 PF07676.7 EFI28617.1 - 0.038 13.6 0.2 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cerato-platanin PF07249.7 EFI28617.1 - 0.041 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 Cerato-platanin UPF0160 PF03690.8 EFI28618.1 - 7e-112 373.9 0.0 1.3e-110 369.7 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF1467 PF07330.7 EFI28619.1 - 0.0049 16.6 0.2 0.014 15.1 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1467) DUF2782 PF11191.3 EFI28619.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Ribosomal_S3_C PF00189.15 EFI28620.1 - 3.8e-16 59.0 0.0 7.3e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EFI28620.1 - 2.1e-12 46.4 0.0 3.7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EFI28620.1 - 0.036 14.3 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Thiolase_N PF00108.18 EFI28621.1 - 7.3e-68 228.4 0.0 1.4e-67 227.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EFI28621.1 - 1.6e-39 134.0 2.2 2.4e-39 133.5 0.2 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EFI28621.1 - 0.0092 15.6 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EFI28621.1 - 0.1 12.0 2.4 0.1 12.0 0.2 2.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Memo PF01875.12 EFI28622.1 - 2.3e-77 259.5 0.0 2.7e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.13 EFI28623.1 - 1.2e-48 163.7 1.7 1.4e-48 163.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Methyltransf_23 PF13489.1 EFI28624.1 - 0.00042 20.0 0.0 0.0016 18.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI28624.1 - 0.018 15.5 0.0 0.05 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EFI28624.1 - 0.046 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SMN PF06003.7 EFI28625.1 - 9.8e-08 31.4 8.7 1.8e-07 30.5 6.0 1.4 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 EFI28625.1 - 3.3e-06 26.9 0.2 8.3e-06 25.6 0.0 1.7 2 1 0 2 2 2 1 Tudor domain Relaxase PF03432.9 EFI28625.1 - 0.0011 18.3 3.1 0.0019 17.6 2.1 1.4 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain RP-C_C PF11800.3 EFI28625.1 - 0.052 13.2 6.8 0.093 12.4 0.2 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region POP1 PF06978.6 EFI28625.1 - 0.1 12.2 6.4 1.3 8.6 1.9 2.1 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Rtf2 PF04641.7 EFI28625.1 - 1.2 8.2 12.0 0.54 9.4 4.4 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3682 PF12446.3 EFI28625.1 - 1.8 8.8 11.7 0.96 9.7 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) RNase_H2-Ydr279 PF09468.5 EFI28625.1 - 5.3 6.1 19.3 4 6.5 8.1 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) RIO1 PF01163.17 EFI28626.1 - 3.5e-49 166.7 0.0 6.4e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EFI28626.1 - 1.2e-33 114.9 0.1 2.4e-33 114.0 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EFI28626.1 - 2.9e-10 40.2 0.0 0.00058 19.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EFI28626.1 - 1.4e-06 27.5 0.0 5.4e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Daxx PF03344.10 EFI28626.1 - 0.29 9.5 24.5 0.39 9.1 17.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EFI28626.1 - 0.9 8.1 21.7 1.3 7.6 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EFI28626.1 - 2.3 7.4 7.7 3.9 6.6 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.5 EFI28626.1 - 3.2 6.7 23.9 4.8 6.1 16.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EFI28626.1 - 4.1 5.1 20.4 5.7 4.7 14.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EFI28626.1 - 6.9 4.5 18.0 10 3.9 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.8 EFI28627.1 - 3.2e-19 69.3 6.6 7.1e-16 58.5 0.3 7.2 6 3 1 7 7 7 2 Peroxisomal membrane anchor protein (Pex14p) conserved region GRIP PF01465.15 EFI28627.1 - 7.7e-18 63.7 0.9 7.7e-18 63.7 0.6 2.4 3 0 0 3 3 3 1 GRIP domain Laminin_II PF06009.7 EFI28627.1 - 0.0025 17.5 1.4 0.0025 17.5 1.0 6.6 4 2 4 8 8 8 3 Laminin Domain II LEDGF PF11467.3 EFI28628.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) JAB PF01398.16 EFI28629.1 - 5.6e-12 45.4 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.8 EFI28629.1 - 0.057 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DPBB_1 PF03330.13 EFI28630.1 - 4.2e-09 36.2 0.3 1e-08 35.0 0.2 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EFI28630.1 - 0.1 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Cerato-platanin SGL PF08450.7 EFI28631.1 - 9.2e-71 238.0 0.0 1.2e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EFI28631.1 - 0.00037 20.4 0.0 0.0021 18.0 0.0 2.0 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.11 EFI28631.1 - 0.00083 19.3 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Strictosidine synthase Lactonase PF10282.4 EFI28631.1 - 0.039 13.0 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller zf-CCCH PF00642.19 EFI28632.1 - 1.1e-16 60.0 23.5 4.3e-05 23.0 0.4 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EFI28632.1 - 0.075 13.0 0.6 0.075 13.0 0.4 5.6 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHC PF00098.18 EFI28632.1 - 0.17 11.8 2.5 0.83 9.6 1.7 2.3 1 0 0 1 1 1 0 Zinc knuckle PDT PF00800.13 EFI28633.1 - 1.8e-51 174.2 0.0 2e-49 167.6 0.0 2.1 1 1 0 1 1 1 1 Prephenate dehydratase eIF2A PF08662.6 EFI28634.1 - 4.8e-44 150.3 0.5 1.2e-39 136.0 0.1 4.4 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EFI28634.1 - 2.8e-07 30.0 0.0 7.6e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EFI28634.1 - 3.3e-06 26.7 2.2 0.11 12.4 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat RRM_6 PF14259.1 EFI28634.1 - 4.4e-06 26.5 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI28634.1 - 0.00034 20.3 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBM_2 PF00553.14 EFI28634.1 - 0.072 13.1 0.8 0.17 11.9 0.6 1.6 1 0 0 1 1 1 0 Cellulose binding domain P4Ha_N PF08336.6 EFI28634.1 - 0.44 10.3 3.8 0.82 9.4 2.6 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Hap4_Hap_bind PF10297.4 EFI28635.1 - 2.7e-07 30.2 4.9 2.7e-07 30.2 3.4 2.4 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EFI28635.1 - 5.9e-05 22.9 14.3 5.9e-05 22.9 9.9 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EFI28635.1 - 0.011 15.5 16.8 0.092 12.5 2.6 2.7 2 1 0 2 2 2 0 Basic region leucine zipper DUF972 PF06156.8 EFI28635.1 - 0.04 14.2 5.8 0.08 13.3 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HALZ PF02183.13 EFI28635.1 - 0.28 10.9 5.2 0.38 10.5 2.6 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3275 PF11679.3 EFI28635.1 - 1.5 8.3 10.2 0.26 10.9 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) ADIP PF11559.3 EFI28635.1 - 5.2 6.9 15.9 8.7 6.2 11.0 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SLX9 PF15341.1 EFI28636.1 - 1.5e-24 86.7 10.0 1.9e-24 86.3 6.9 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF1168 PF06658.7 EFI28636.1 - 0.44 10.0 7.0 0.54 9.7 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) DUF914 PF06027.7 EFI28637.1 - 2.1e-08 33.4 2.4 3.2e-06 26.2 0.2 2.5 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EFI28637.1 - 4.6e-07 29.9 4.0 4.6e-07 29.9 2.8 3.1 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EFI28637.1 - 1.4e-05 25.2 3.5 1.4e-05 25.2 2.4 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EFI28637.1 - 0.00013 21.0 1.7 0.00015 20.8 0.2 1.7 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.11 EFI28637.1 - 0.0014 18.3 0.8 0.0014 18.3 0.5 2.8 3 0 0 3 3 3 1 Triose-phosphate Transporter family Glyco_transf_8 PF01501.15 EFI28638.1 - 2.8e-32 112.0 0.0 3.9e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EFI28638.1 - 0.0039 16.5 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Ribosomal_S28e PF01200.13 EFI28639.1 - 1.8e-34 117.2 1.9 2e-34 117.1 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_L11_N PF03946.9 EFI28641.1 - 0.065 12.7 0.2 0.13 11.7 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Aconitase PF00330.15 EFI28644.1 - 8.1e-161 535.6 0.0 8.4e-160 532.2 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EFI28644.1 - 3.2e-39 134.0 0.0 5.7e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_hydro_3 PF00933.16 EFI28645.1 - 3.5e-64 216.6 0.0 6.5e-64 215.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EFI28645.1 - 9.9e-45 152.8 3.2 3e-39 134.8 0.1 3.3 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EFI28645.1 - 1e-20 73.4 0.0 2.2e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 EFI28645.1 - 2.3e-14 52.7 10.7 6.8e-14 51.2 7.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Chromo PF00385.19 EFI28646.1 - 1.3e-08 34.3 5.6 3.8e-08 32.8 3.9 1.9 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Oxidored_q2 PF00420.19 EFI28647.1 - 0.072 12.6 0.3 0.12 12.0 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Atg14 PF10186.4 EFI28649.1 - 6.4e-15 54.8 0.0 2.6e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 DUF1319 PF07028.6 EFI28649.1 - 0.09 12.9 3.9 0.073 13.2 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Pex2_Pex12 PF04757.9 EFI28650.1 - 1.3e-28 99.9 3.4 2.9e-28 98.8 2.4 1.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 EFI28650.1 - 2.1e-09 36.9 4.4 2.9e-09 36.4 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EFI28650.1 - 4.1e-09 35.9 6.6 6.2e-09 35.3 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EFI28650.1 - 5.7e-09 35.8 8.1 8.8e-09 35.2 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EFI28650.1 - 1.1e-08 34.7 8.4 2.4e-08 33.6 5.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EFI28650.1 - 5.7e-07 29.1 6.2 9e-07 28.5 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EFI28650.1 - 4.9e-05 23.3 1.3 0.0001 22.3 0.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EFI28650.1 - 0.0046 16.6 3.3 0.0054 16.4 1.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EFI28650.1 - 0.0048 16.7 7.1 0.01 15.6 4.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EFI28650.1 - 0.016 14.9 1.8 0.032 14.0 1.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 EFI28650.1 - 0.018 15.0 1.0 0.029 14.2 0.7 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.1 EFI28650.1 - 0.047 13.4 2.6 0.088 12.6 1.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EFI28650.1 - 0.083 12.4 4.7 0.18 11.3 3.2 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EFI28650.1 - 0.23 11.0 5.2 0.38 10.3 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ECIST_Cterm PF14784.1 EFI28650.1 - 0.31 11.0 1.3 2.5 8.0 0.0 2.7 3 0 0 3 3 3 0 C-terminal domain of the ECSIT protein IBR PF01485.16 EFI28650.1 - 4 7.3 8.0 9.8 6.1 5.2 1.8 1 1 0 1 1 1 0 IBR domain LSM PF01423.17 EFI28651.1 - 2.4e-14 52.5 0.8 3.3e-14 52.1 0.5 1.2 1 0 0 1 1 1 1 LSM domain HATPase_c PF02518.21 EFI28652.1 - 1e-29 102.4 0.1 2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EFI28652.1 - 1.6e-21 76.4 0.0 7.3e-18 64.6 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain AAA_16 PF13191.1 EFI28652.1 - 8.2e-20 71.5 1.8 1.9e-18 67.1 0.5 3.0 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.20 EFI28652.1 - 3.7e-16 58.8 0.1 1.5e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EFI28652.1 - 4.6e-09 36.9 0.0 1.7e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EFI28652.1 - 2.6e-08 33.3 0.0 2.7e-07 30.0 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain GAF_3 PF13492.1 EFI28652.1 - 4.1e-08 33.3 0.0 1.3e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 EFI28652.1 - 0.0022 17.6 0.1 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.12 EFI28652.1 - 0.0038 16.3 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EFI28652.1 - 0.0042 16.9 6.1 0.071 13.0 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 EFI28652.1 - 0.0052 16.9 0.4 0.43 10.7 0.1 3.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EFI28652.1 - 0.017 14.8 2.4 0.065 12.8 1.7 2.1 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EFI28652.1 - 0.018 14.7 0.1 9.4 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EFI28652.1 - 0.36 10.5 0.3 22 4.6 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase HMG_box PF00505.14 EFI28653.1 - 2.4e-13 50.1 0.1 4.9e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EFI28653.1 - 1.1e-05 25.6 0.1 2.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain DUF4558 PF15104.1 EFI28653.1 - 0.063 13.2 1.4 0.12 12.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) DUF1950 PF09187.5 EFI28653.1 - 0.1 12.7 0.9 0.49 10.5 0.6 2.1 1 1 0 1 1 1 0 Domain of unknown function(DUF1950) Arm PF00514.18 EFI28654.1 - 5.9e-61 200.3 33.2 3.6e-13 48.7 0.1 11.4 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EFI28654.1 - 8e-23 80.5 7.1 0.00034 20.8 0.0 7.4 2 2 5 7 7 7 7 HEAT repeats HEAT PF02985.17 EFI28654.1 - 9.8e-17 59.4 13.4 0.013 15.5 0.0 9.5 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EFI28654.1 - 5.7e-13 48.9 11.1 0.031 14.7 0.1 8.2 5 2 4 9 9 9 5 HEAT-like repeat Arm_2 PF04826.8 EFI28654.1 - 1.4e-10 40.7 10.1 1.5e-07 30.8 1.1 3.1 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.15 EFI28654.1 - 1.5e-10 40.0 9.8 3.5e-08 32.2 0.1 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 EFI28654.1 - 2.4e-08 32.3 2.2 4.4e-08 31.5 1.5 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EFI28654.1 - 3.3e-07 29.7 7.1 0.00065 18.9 2.0 4.1 2 1 2 4 4 4 3 V-ATPase subunit H HEAT_PBS PF03130.11 EFI28654.1 - 0.0025 18.1 3.0 1.2e+02 3.5 0.0 6.6 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EFI28654.1 - 0.0075 16.1 3.1 9.2 6.2 0.0 4.2 2 1 2 4 4 4 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EFI28654.1 - 0.022 15.1 0.0 11 6.4 0.0 3.4 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region PIF1 PF05970.9 EFI28655.1 - 4.6e-61 206.7 0.0 5.7e-45 153.8 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase Cauli_VI PF01693.11 EFI28655.1 - 3.4e-15 55.7 0.4 7.7e-15 54.6 0.3 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_30 PF13604.1 EFI28655.1 - 6.6e-14 51.9 0.0 2.9e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 EFI28655.1 - 1.6e-05 22.9 0.9 0.00014 19.8 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EFI28655.1 - 0.00012 22.1 0.0 0.00085 19.4 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EFI28655.1 - 0.00019 21.5 0.0 0.00074 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EFI28655.1 - 0.00036 20.5 3.0 0.016 15.2 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 EFI28655.1 - 0.00064 19.3 0.5 0.75 9.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EFI28655.1 - 0.0015 17.8 0.1 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EFI28655.1 - 0.013 15.2 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Helicase_RecD PF05127.9 EFI28655.1 - 0.014 15.0 0.2 2.5 7.6 0.0 3.0 2 1 0 2 2 2 0 Helicase ABC_tran PF00005.22 EFI28655.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EFI28655.1 - 0.073 12.8 0.2 0.95 9.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EFI28655.1 - 0.077 12.4 0.0 2.9 7.2 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.1 EFI28655.1 - 0.1 12.1 0.1 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EFI28655.1 - 0.92 9.0 4.4 1.5 8.3 0.1 2.9 3 2 0 3 3 3 0 AAA domain Glyco_hydro_72 PF03198.9 EFI28656.1 - 2e-94 316.1 0.0 2.7e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EFI28656.1 - 3.4e-16 59.4 0.1 8.7e-16 58.1 0.1 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EFI28656.1 - 0.0075 15.4 0.0 0.018 14.2 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SUR7 PF06687.7 EFI28657.1 - 1.1e-16 61.0 5.0 1.4e-16 60.7 3.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF805 PF05656.9 EFI28657.1 - 0.1 12.4 6.1 0.042 13.6 1.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF2721 PF11026.3 EFI28657.1 - 1.9 8.1 8.3 6.7 6.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RIC1 PF07064.8 EFI28658.1 - 4.5e-72 242.5 1.0 6.3e-72 242.1 0.7 1.2 1 0 0 1 1 1 1 RIC1 IKI3 PF04762.7 EFI28658.1 - 0.16 9.7 0.0 14 3.3 0.0 2.7 3 0 0 3 3 3 0 IKI3 family PRELI PF04707.9 EFI28659.1 - 1.7e-33 115.3 0.0 2.2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Lactamase_B_2 PF12706.2 EFI28660.1 - 6.9e-12 45.3 0.0 2.1e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EFI28660.1 - 3.3e-10 39.9 0.3 6.6e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PIN PF01850.16 EFI28660.1 - 0.037 14.3 0.0 0.21 11.9 0.0 1.9 1 1 1 2 2 2 0 PIN domain Lactamase_B_3 PF13483.1 EFI28660.1 - 0.064 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pkinase PF00069.20 EFI28661.1 - 5.5e-64 215.8 0.0 1e-63 214.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28661.1 - 1.7e-34 119.0 0.0 1.8e-33 115.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI28661.1 - 6.6e-08 31.8 0.0 2e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EFI28661.1 - 0.0002 21.1 0.0 0.0067 16.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EFI28661.1 - 0.0017 17.2 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 BTD PF09270.5 EFI28662.1 - 9.1e-26 90.4 0.0 1.9e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain LAG1-DNAbind PF09271.6 EFI28662.1 - 1.5e-25 90.2 0.0 3.8e-24 85.7 0.0 2.3 1 1 0 1 1 1 1 LAG1, DNA binding DEAD PF00270.24 EFI28664.1 - 5.8e-14 51.9 0.0 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EFI28664.1 - 7.7e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.19 EFI28665.1 - 2.9e-102 342.5 13.6 3.3e-102 342.3 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EFI28665.1 - 2.8e-27 95.3 26.5 8.6e-22 77.3 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EFI28665.1 - 1.5e-07 30.1 14.3 0.0001 20.8 2.2 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein TRAPPC-Trs85 PF12739.2 EFI28666.1 - 1.5e-33 116.0 0.0 3.4e-28 98.4 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 EFI28666.1 - 1.2e-07 29.5 0.0 1.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_14 PF13428.1 EFI28666.1 - 0.1 13.3 0.1 60 4.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat WW PF00397.21 EFI28667.1 - 0.025 14.4 0.1 0.025 14.4 0.1 1.8 2 0 0 2 2 2 0 WW domain DUF2076 PF09849.4 EFI28667.1 - 0.11 12.4 7.3 0.14 12.2 4.1 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) TatD_DNase PF01026.16 EFI28668.1 - 3.9e-32 111.4 0.0 2.3e-29 102.3 0.0 2.1 1 1 1 2 2 2 2 TatD related DNase Glyco_transf_21 PF13506.1 EFI28669.1 - 6.1e-26 90.7 0.5 3.5e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EFI28669.1 - 3e-19 69.7 0.1 4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EFI28669.1 - 6.6e-11 42.2 2.0 6.6e-11 42.2 1.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EFI28669.1 - 6.9e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 MMR_HSR1 PF01926.18 EFI28670.1 - 7.1e-16 58.2 0.1 1.3e-14 54.1 0.0 2.9 4 0 0 4 4 4 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EFI28670.1 - 4.1e-05 22.9 0.0 0.00022 20.5 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EFI28670.1 - 0.0001 21.5 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EFI28670.1 - 0.00024 20.2 0.8 0.0004 19.5 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EFI28670.1 - 0.04 13.7 0.1 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Dynamin family Miro PF08477.8 EFI28670.1 - 0.12 12.8 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Pkinase PF00069.20 EFI28671.1 - 2.3e-19 69.5 0.1 4.6e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28671.1 - 4.4e-10 39.0 0.0 4.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4125 PF13526.1 EFI28671.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) Med7 PF05983.6 EFI28672.1 - 3.7e-27 95.0 0.1 6.1e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 MED7 protein Hs1pro-1_N PF07231.7 EFI28672.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Hs1pro-1 N-terminus nsp8 PF08717.5 EFI28672.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 nsp8 replicase AMP-binding PF00501.23 EFI28673.1 - 4.3e-81 272.4 0.0 8.5e-81 271.4 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EFI28673.1 - 1e-11 45.5 0.7 3.7e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF3353 PF11833.3 EFI28674.1 - 1.8 7.9 6.5 3.6 7.0 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF3591 PF12157.3 EFI28675.1 - 1.7e-168 560.7 1.9 3.1e-168 559.8 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EFI28675.1 - 0.00013 21.5 2.2 0.00028 20.4 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle ParA PF10609.4 EFI28676.1 - 8.6e-33 112.0 0.1 1.6e-32 111.1 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EFI28676.1 - 1.4e-13 50.6 0.0 2.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EFI28676.1 - 4e-06 26.8 0.0 3.9e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EFI28676.1 - 1.4e-05 24.2 0.3 0.0006 18.9 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EFI28676.1 - 7.7e-05 21.8 0.0 0.0045 16.1 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.1 EFI28676.1 - 0.013 15.0 0.2 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EFI28676.1 - 0.033 13.3 0.1 0.056 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Desulfoferrod_N PF06397.7 EFI28676.1 - 0.047 13.0 1.0 0.11 11.8 0.7 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain AAA_25 PF13481.1 EFI28676.1 - 0.049 13.0 0.2 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EFI28676.1 - 0.05 13.3 0.1 0.56 9.9 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain Homeobox PF00046.24 EFI28677.1 - 7.5e-17 60.7 2.7 1.9e-16 59.4 1.9 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EFI28677.1 - 2.9e-08 33.2 0.8 1e-07 31.4 0.5 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EFI28677.1 - 0.00011 21.2 0.1 0.00025 20.0 0.1 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF1741 PF08427.5 EFI28678.1 - 0.025 14.0 0.1 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) zf-C2H2_4 PF13894.1 EFI28679.1 - 6.3 7.3 5.8 12 6.5 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Transthyretin PF00576.16 EFI28680.1 - 2.1e-28 98.4 0.2 5.3e-28 97.1 0.1 1.6 1 1 0 1 1 1 1 HIUase/Transthyretin family Methyltransf_23 PF13489.1 EFI28681.1 - 4.6e-07 29.6 0.0 5.8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EFI28681.1 - 6.7e-06 26.6 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EFI28681.1 - 5.1e-05 22.8 0.0 7.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EFI28681.1 - 9.5e-05 21.5 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EFI28681.1 - 0.00066 19.6 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EFI28681.1 - 0.0045 16.3 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EFI28681.1 - 0.0068 16.4 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EFI28681.1 - 0.019 14.1 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_12 PF08242.7 EFI28681.1 - 0.024 15.0 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EFI28681.1 - 0.033 14.6 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EFI28681.1 - 0.054 13.8 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EFI28681.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) BEX PF04538.7 EFI28682.1 - 0.18 12.0 1.1 1.7 8.8 0.8 2.3 1 1 0 1 1 1 0 Brain expressed X-linked like family RhoGEF PF00621.15 EFI28683.1 - 3.9e-07 30.1 0.0 6.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain HTH_38 PF13936.1 EFI28683.1 - 0.1 12.1 0.6 3 7.4 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Aminotran_4 PF01063.14 EFI28684.1 - 5.6e-24 84.8 0.0 7.2e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV NIPSNAP PF07978.8 EFI28685.1 - 0.017 15.0 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 NIPSNAP MLTD_N PF06474.7 EFI28685.1 - 0.23 11.6 1.1 0.39 10.9 0.7 1.3 1 0 0 1 1 1 0 MltD lipid attachment motif Proteasome PF00227.21 EFI28686.1 - 4.8e-36 123.8 0.0 5.5e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MoaC PF01967.16 EFI28687.1 - 2e-41 140.8 0.2 2.8e-36 124.1 0.4 2.4 1 1 1 2 2 2 2 MoaC family Mob_synth_C PF06463.8 EFI28687.1 - 2.9e-37 127.1 0.0 5e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EFI28687.1 - 2.8e-24 86.1 0.0 4.3e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EFI28687.1 - 1.3e-06 28.5 0.0 3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EFI28687.1 - 9.8e-05 22.3 0.0 0.00035 20.5 0.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain V-SNARE_C PF12352.3 EFI28688.1 - 5.9e-15 55.0 2.6 5.9e-15 55.0 1.8 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Ax_dynein_light PF10211.4 EFI28688.1 - 0.0089 15.8 0.8 0.016 15.0 0.5 1.5 1 0 0 1 1 1 1 Axonemal dynein light chain AAA_27 PF13514.1 EFI28688.1 - 0.016 12.9 7.2 0.019 12.6 5.0 1.0 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 EFI28688.1 - 0.023 14.2 3.6 0.022 14.3 0.9 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spectrin PF00435.16 EFI28688.1 - 0.032 14.5 4.3 0.92 9.8 0.2 2.6 1 1 1 2 2 2 0 Spectrin repeat V_ATPase_I PF01496.14 EFI28688.1 - 0.07 10.9 0.6 0.071 10.9 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec20 PF03908.8 EFI28688.1 - 0.081 12.6 1.4 0.8 9.4 0.0 2.6 2 1 1 3 3 3 0 Sec20 AAA_13 PF13166.1 EFI28688.1 - 0.083 11.3 1.8 0.13 10.6 0.9 1.4 1 1 0 1 1 1 0 AAA domain Vip3A_N PF12495.3 EFI28688.1 - 0.12 12.0 0.8 5.4 6.6 0.5 2.2 1 1 0 1 1 1 0 Vegetative insecticide protein 3A N terminal CDC37_N PF03234.9 EFI28688.1 - 0.13 12.6 2.8 0.17 12.2 1.9 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Sugarporin_N PF11471.3 EFI28688.1 - 0.45 10.2 2.9 0.64 9.7 0.4 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Occludin_ELL PF07303.8 EFI28688.1 - 0.63 10.8 2.6 4.7 7.9 0.3 2.9 1 1 2 3 3 3 0 Occludin homology domain APG6 PF04111.7 EFI28688.1 - 0.66 8.9 5.2 0.4 9.6 2.4 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EFI28688.1 - 1.2 8.9 8.9 0.47 10.3 1.9 2.5 1 1 2 3 3 3 0 Tropomyosin like Nup54 PF13874.1 EFI28688.1 - 1.3 8.6 5.8 0.62 9.7 0.6 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF2358 PF10184.4 EFI28689.1 - 0.00047 20.0 0.0 0.00064 19.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.2 EFI28689.1 - 0.069 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DUF2358 PF10184.4 EFI28690.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.2 EFI28690.1 - 0.029 14.7 0.0 0.11 12.8 0.0 1.9 1 1 0 2 2 2 0 SnoaL-like domain ABC_membrane PF00664.18 EFI28691.1 - 3.4e-49 167.7 11.5 1.3e-29 103.5 0.5 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EFI28691.1 - 7.1e-47 159.1 1.5 6.5e-30 104.2 0.1 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EFI28691.1 - 7.5e-11 42.5 0.6 0.14 12.1 0.0 4.4 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EFI28691.1 - 2.8e-10 39.8 6.0 6.8e-05 22.2 0.1 4.4 5 0 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EFI28691.1 - 5.7e-09 35.3 1.5 0.0031 16.9 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EFI28691.1 - 2.5e-08 33.1 0.1 0.0017 17.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EFI28691.1 - 8.6e-07 28.5 0.0 0.029 13.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EFI28691.1 - 5.7e-06 26.8 1.1 0.0039 17.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EFI28691.1 - 7.4e-06 26.4 0.1 0.21 12.1 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EFI28691.1 - 1.7e-05 24.3 0.1 0.2 11.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 EFI28691.1 - 1.8e-05 24.9 2.0 0.3 11.2 0.7 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EFI28691.1 - 2.4e-05 24.4 0.1 0.35 10.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EFI28691.1 - 4e-05 23.5 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EFI28691.1 - 0.00021 21.5 1.6 0.32 11.2 0.1 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EFI28691.1 - 0.00022 22.0 1.0 0.36 11.6 0.4 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EFI28691.1 - 0.00025 20.9 0.0 0.44 10.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EFI28691.1 - 0.00027 20.8 3.5 0.0063 16.3 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 EFI28691.1 - 0.00034 19.8 0.0 0.79 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EFI28691.1 - 0.00036 20.4 1.9 0.13 12.1 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_10 PF12846.2 EFI28691.1 - 0.00047 19.6 1.0 0.9 8.9 0.1 2.8 2 1 1 3 3 3 2 AAA-like domain Zeta_toxin PF06414.7 EFI28691.1 - 0.00054 19.1 0.3 0.4 9.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin cobW PF02492.14 EFI28691.1 - 0.0006 19.3 0.3 0.33 10.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EFI28691.1 - 0.0024 17.7 0.0 1.8 8.4 0.0 3.1 2 1 1 3 3 3 1 AAA domain Adeno_IVa2 PF02456.10 EFI28691.1 - 0.0064 15.1 0.1 1.1 7.8 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.4 EFI28691.1 - 0.011 14.4 1.0 1.6 7.2 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 EFI28691.1 - 0.014 14.8 0.1 4 6.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EFI28691.1 - 0.015 15.0 1.7 0.41 10.3 0.1 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EFI28691.1 - 0.017 14.0 0.2 1.5 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EFI28691.1 - 0.02 14.5 0.0 4.1 7.0 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EFI28691.1 - 0.04 13.5 2.2 3.1 7.4 0.0 3.0 2 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 EFI28691.1 - 0.041 13.4 0.2 4 6.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EFI28691.1 - 0.093 11.4 0.6 0.62 8.7 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 EFI28691.1 - 0.15 11.8 0.4 13 5.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EFI28691.1 - 0.18 11.9 0.1 19 5.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.4 EFI28691.1 - 0.25 10.2 1.0 4.7 6.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EFI28691.1 - 0.29 10.8 3.1 2.1 8.0 0.1 3.2 3 0 0 3 3 3 0 NTPase Lum_binding PF00677.12 EFI28692.1 - 4.9e-36 122.4 0.0 2e-18 66.0 0.0 2.4 2 0 0 2 2 2 2 Lumazine binding domain Myosin_head PF00063.16 EFI28693.1 - 7.2e-213 708.4 0.3 6.9e-211 701.9 0.2 2.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EFI28693.1 - 5.8e-46 156.3 0.0 1e-45 155.4 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_9 PF14604.1 EFI28693.1 - 1.6e-07 30.8 0.4 3.6e-07 29.6 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EFI28693.1 - 1.7e-07 30.5 1.2 3.5e-07 29.4 0.8 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EFI28693.1 - 7.8e-07 28.4 0.0 1.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain UNC45-central PF11701.3 EFI28693.1 - 3.2e-06 26.8 0.2 7.8e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central SH3_3 PF08239.6 EFI28693.1 - 0.0032 17.6 0.7 0.0081 16.3 0.5 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Hpr_kinase_C PF07475.7 EFI28693.1 - 0.012 14.9 0.5 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 EFI28693.1 - 0.016 15.3 0.0 0.053 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EFI28693.1 - 0.026 13.5 0.0 0.083 11.9 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EFI28693.1 - 0.054 14.3 0.1 0.24 12.2 0.0 2.3 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EFI28693.1 - 0.1 12.2 0.2 0.52 9.9 0.1 2.2 2 0 0 2 2 2 0 NACHT domain ACT_7 PF13840.1 EFI28694.1 - 2.1e-18 65.5 0.0 3.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 ACT domain Peptidase_M24 PF00557.19 EFI28695.1 - 2.8e-43 147.9 0.1 4.2e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Bromodomain PF00439.20 EFI28695.1 - 2.5e-37 126.6 0.7 9.2e-19 67.1 0.0 2.8 2 0 0 2 2 2 2 Bromodomain Nop53 PF07767.6 EFI28695.1 - 0.084 11.8 17.3 0.04 12.9 0.8 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Pkinase PF00069.20 EFI28696.1 - 4.1e-72 242.4 0.0 6.1e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EFI28696.1 - 7.9e-53 179.1 0.0 1.1e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EFI28696.1 - 1.2e-05 24.4 0.0 0.00027 19.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 EFI28696.1 - 0.0011 18.2 0.4 0.0023 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) NAD_binding_2 PF03446.10 EFI28697.1 - 8.2e-21 74.5 0.0 3.9e-20 72.3 0.0 1.9 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EFI28697.1 - 1.5e-10 41.2 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EFI28697.1 - 6e-08 33.0 0.1 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EFI28697.1 - 7.6e-07 29.3 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EFI28697.1 - 0.00012 21.3 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EFI28697.1 - 0.00022 20.9 0.2 0.00043 20.0 0.1 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_3 PF03447.11 EFI28697.1 - 0.0073 16.6 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EFI28697.1 - 0.014 15.8 0.1 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ThiF PF00899.16 EFI28697.1 - 0.055 13.2 1.1 0.31 10.8 0.7 2.1 1 1 0 1 1 1 0 ThiF family IlvN PF07991.7 EFI28697.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain PAH PF02671.16 EFI28698.1 - 9.7e-18 63.5 1.8 2e-12 46.5 0.1 3.1 3 1 0 3 3 3 2 Paired amphipathic helix repeat UQ_con PF00179.21 EFI28700.1 - 1.7e-25 89.0 0.0 2.1e-24 85.5 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EFI28700.1 - 0.00024 20.7 0.0 0.00066 19.3 0.0 1.8 1 0 0 1 1 1 1 UEV domain FoP_duplication PF13865.1 EFI28700.1 - 9.5 6.7 7.0 15 6.1 0.2 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 PIP5K PF01504.13 EFI28703.1 - 1.4e-66 224.1 0.1 2.6e-66 223.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EFI28703.1 - 1.5e-24 86.5 0.0 2.5e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EFI28703.1 - 1.1e-17 63.6 9.4 1.9e-17 62.8 5.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.16 EFI28703.1 - 0.26 11.1 8.5 0.3 10.9 3.2 2.5 2 0 0 2 2 2 0 IBR domain AAA_23 PF13476.1 EFI28703.1 - 5.8 7.1 5.6 14 5.9 3.9 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L1 PF00687.16 EFI28704.1 - 4e-15 55.7 0.1 3.5e-09 36.3 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family dsrm PF00035.20 EFI28705.1 - 4.9e-12 46.2 0.0 5.9e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EFI28705.1 - 0.13 12.5 0.0 0.21 11.9 0.0 1.4 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 EGF_3 PF12947.2 EFI28705.1 - 0.13 12.2 0.3 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 EGF domain DUF2404 PF10296.4 EFI28706.1 - 1.6e-28 98.6 0.0 3.8e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DSHCT PF08148.7 EFI28708.1 - 1.4e-59 200.3 0.3 3.3e-59 199.1 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EFI28708.1 - 1.5e-19 70.1 0.1 7.7e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EFI28708.1 - 6.2e-07 28.8 0.0 9.5e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EFI28708.1 - 1.9e-05 24.4 0.0 4.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3391 PF11871.3 EFI28709.1 - 0.033 14.3 0.1 0.038 14.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) WLM PF08325.5 EFI28710.1 - 4.5e-44 150.5 0.0 6.9e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EFI28710.1 - 4.7e-05 22.4 2.1 4.7e-05 22.4 1.5 3.2 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EFI28710.1 - 0.00034 20.4 0.1 0.0024 17.6 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF45 DZR PF12773.2 EFI28710.1 - 0.0057 16.4 7.8 0.013 15.3 5.4 1.6 1 0 0 1 1 1 1 Double zinc ribbon zf-piccolo PF05715.8 EFI28710.1 - 0.069 13.1 1.9 0.18 11.8 1.3 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger OrfB_Zn_ribbon PF07282.6 EFI28710.1 - 1.6 8.4 7.9 0.49 10.0 0.8 3.1 1 1 2 3 3 3 0 Putative transposase DNA-binding domain RicinB_lectin_2 PF14200.1 EFI28711.1 - 0.0057 17.0 0.0 0.021 15.2 0.0 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EFI28711.1 - 0.14 12.1 0.0 0.57 10.2 0.0 1.9 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain NIF PF03031.13 EFI28712.1 - 3e-25 88.7 0.0 3.7e-22 78.7 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Inositol_P PF00459.20 EFI28714.1 - 5.3e-53 180.0 0.6 1.3e-52 178.8 0.4 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family CPSase_L_D2 PF02786.12 EFI28715.1 - 4.1e-72 241.8 0.0 7.7e-72 240.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EFI28715.1 - 4.5e-44 149.0 0.5 2.1e-43 146.8 0.0 2.4 3 0 0 3 3 3 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EFI28715.1 - 7.9e-32 109.4 0.0 1.9e-31 108.1 0.0 1.7 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain ADH_zinc_N PF00107.21 EFI28715.1 - 3.4e-17 62.1 0.2 2.1e-16 59.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Biotin_lipoyl PF00364.17 EFI28715.1 - 2.5e-16 59.0 1.9 7.7e-16 57.5 1.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EFI28715.1 - 2.6e-14 52.7 0.0 8.6e-14 51.0 0.0 1.8 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EFI28715.1 - 2.7e-11 43.5 0.0 1.2e-10 41.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ADH_N PF08240.7 EFI28715.1 - 1.1e-08 34.7 0.0 7e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Biotin_lipoyl_2 PF13533.1 EFI28715.1 - 1e-07 31.4 1.3 0.00012 21.7 0.1 3.1 2 1 1 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EFI28715.1 - 3.6e-06 26.5 0.0 1.1e-05 24.9 0.0 1.8 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus RnfC_N PF13375.1 EFI28715.1 - 0.0004 20.0 0.3 0.06 13.0 0.2 2.7 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 EFI28715.1 - 0.0011 18.3 1.3 0.1 11.8 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EFI28715.1 - 0.0013 19.0 0.2 2.1 8.7 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 EFI28715.1 - 0.031 13.9 0.7 0.063 12.9 0.5 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Toxin_59 PF15537.1 EFI28715.1 - 0.095 12.7 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Putative toxin 59 NQRA PF05896.6 EFI28715.1 - 0.096 11.8 0.3 0.17 11.0 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 EFI28715.1 - 0.25 10.4 1.1 5.8 5.9 0.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Calreticulin PF00262.13 EFI28716.1 - 3.5e-152 506.3 11.2 5e-152 505.7 7.8 1.2 1 0 0 1 1 1 1 Calreticulin family SAM_PNT PF02198.11 EFI28716.1 - 0.077 12.7 0.1 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain GTP_EFTU PF00009.22 EFI28717.1 - 1.8e-41 141.6 0.0 3.4e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EFI28717.1 - 1.4e-26 92.3 0.0 3.2e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EFI28717.1 - 2.2e-20 72.3 0.0 4.7e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EFI28717.1 - 4.8e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EFI28717.1 - 1.9e-06 27.8 0.1 4.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EFI28717.1 - 1.2e-05 25.0 0.0 3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EFI28717.1 - 1.7e-05 25.3 0.1 3.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EFI28717.1 - 0.0072 15.5 0.1 0.023 13.8 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EFI28717.1 - 0.016 15.0 0.1 5.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.13 EFI28717.1 - 0.031 13.5 0.1 0.074 12.3 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B GBP PF02263.14 EFI28717.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain GFA PF04828.9 EFI28718.1 - 2.4e-16 59.4 0.5 3.3e-16 58.9 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sgf11 PF08209.6 EFI28718.1 - 0.16 11.2 4.6 4.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CDC45 PF02724.9 EFI28720.1 - 0.49 8.3 2.9 0.67 7.9 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.2 EFI28722.1 - 0.00051 19.6 0.9 0.0019 17.8 0.6 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EFI28722.1 - 4.8 6.9 7.1 17 5.2 0.3 3.2 3 0 0 3 3 3 0 F-box domain DP PF08781.5 EFI28723.1 - 0.11 12.2 0.1 1.8 8.2 0.0 2.3 2 1 0 2 2 2 0 Transcription factor DP zf-C2H2_jaz PF12171.3 EFI28724.1 - 5.6e-16 58.1 32.1 9.9e-05 22.3 2.4 5.2 5 0 0 5 5 5 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EFI28724.1 - 1.6e-08 34.2 27.5 0.015 15.6 0.4 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EFI28724.1 - 3.5e-08 33.3 25.6 0.024 14.9 1.1 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-met PF12874.2 EFI28724.1 - 1.5e-05 25.0 12.9 0.13 12.5 0.1 4.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EFI28724.1 - 0.00039 20.4 15.0 0.086 12.9 6.2 3.3 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) Ecl1 PF12855.2 EFI28724.1 - 0.00098 18.3 20.3 1.9 7.8 0.1 5.1 4 1 1 5 5 5 4 Life-span regulatory factor DZR PF12773.2 EFI28724.1 - 0.023 14.5 13.9 3.1 7.6 4.1 3.4 1 1 1 2 2 2 0 Double zinc ribbon DUF4187 PF13821.1 EFI28724.1 - 0.05 13.2 26.0 0.096 12.2 0.3 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4187) FYVE PF01363.16 EFI28724.1 - 0.51 10.2 19.4 41 4.1 2.2 3.4 1 1 1 2 2 2 0 FYVE zinc finger DUF3795 PF12675.2 EFI28724.1 - 2.2 8.5 11.7 5.1 7.3 1.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3795) zinc-ribbons_6 PF07191.7 EFI28724.1 - 6 6.7 18.5 16 5.4 0.4 4.5 1 1 2 3 3 3 0 zinc-ribbons Thioredoxin_7 PF13899.1 EFI28724.1 - 6.1 6.9 7.4 23 5.0 0.2 3.0 2 1 0 2 2 2 0 Thioredoxin-like DUF2151 PF10221.4 EFI28730.1 - 5.2 5.1 6.8 5.5 5.0 4.7 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF605 PF04652.11 EFI28730.1 - 7.5 5.8 9.4 8 5.7 6.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF3413 PF11893.3 EFI28731.1 - 0.021 13.7 0.1 0.021 13.7 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3413) DUF3172 PF11371.3 EFI28731.1 - 0.15 11.5 0.2 3.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) zf-C2H2_4 PF13894.1 EFI28735.1 - 1.3e-06 28.2 6.8 0.0039 17.4 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EFI28735.1 - 1.9e-06 27.8 3.3 1.9e-06 27.8 2.3 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EFI28735.1 - 8.1e-06 25.8 18.9 0.00044 20.4 1.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EFI28735.1 - 0.0029 17.4 0.3 0.0071 16.2 0.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger GTP_cyclohydroI PF01227.17 EFI28736.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 GTP cyclohydrolase I SMC_hinge PF06470.8 EFI28737.1 - 8.3e-29 99.9 0.2 4.3e-28 97.6 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 EFI28737.1 - 1.1e-25 90.1 37.7 2.5e-25 89.0 26.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EFI28737.1 - 5.2e-06 26.6 0.1 5.2e-06 26.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 EFI28737.1 - 0.00034 19.9 15.4 0.02 14.0 1.3 3.8 2 2 0 3 3 3 3 Reovirus sigma C capsid protein DUF911 PF06023.7 EFI28737.1 - 0.44 9.7 11.0 0.03 13.5 1.6 2.8 3 0 0 3 3 3 0 Archaeal protein of unknown function (DUF911) AAA_13 PF13166.1 EFI28737.1 - 4.3 5.6 89.4 0.044 12.2 13.3 4.7 3 2 2 5 5 5 0 AAA domain Imm42 PF15601.1 EFI28737.1 - 5.1 6.5 14.0 0.39 10.1 1.3 3.7 3 2 1 4 4 4 0 Immunity protein 42 SMC_N PF02463.14 EFI28738.1 - 1.3e-39 135.7 0.0 2.8e-39 134.6 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EFI28738.1 - 1e-16 61.9 0.7 2.1e-16 60.8 0.5 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EFI28738.1 - 2.4e-07 31.0 0.5 5.5e-07 29.8 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EFI28738.1 - 2.6e-07 30.0 0.0 5e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EFI28738.1 - 0.0016 17.5 0.1 0.0024 16.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EFI28738.1 - 0.013 15.8 2.4 0.14 12.4 1.6 2.4 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 EFI28738.1 - 0.029 14.3 0.0 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase APG6 PF04111.7 EFI28738.1 - 0.14 11.1 3.8 0.25 10.3 2.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF87 PF01935.12 EFI28738.1 - 0.77 9.5 3.9 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Nop10p PF04135.7 EFI28739.1 - 1.4e-21 75.9 0.2 1.6e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Senescence_reg PF04520.8 EFI28740.1 - 0.081 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Senescence regulator PRANC PF09372.5 EFI28741.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Utp14 PF04615.8 EFI28742.1 - 7e-150 500.5 98.7 7e-150 500.5 68.4 3.7 1 1 2 3 3 3 1 Utp14 protein Lectin_legB PF00139.14 EFI28745.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Legume lectin domain RRM_1 PF00076.17 EFI28746.1 - 8.2e-19 67.0 0.0 1.2e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EFI28746.1 - 8.1e-15 54.5 0.0 1.2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EFI28746.1 - 2.9e-10 39.8 0.0 4.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EFI28746.1 - 0.00014 21.6 9.8 0.00014 21.6 6.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) UBA_e1_thiolCys PF10585.4 EFI28748.1 - 0.05 12.9 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Glyco_hydro_108 PF05838.7 EFI28751.1 - 0.12 12.4 0.1 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase 108 Peptidase_M76 PF09768.4 EFI28753.1 - 4e-67 225.0 4.1 4.7e-67 224.7 2.9 1.1 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.1 EFI28753.1 - 0.014 14.9 0.2 0.018 14.5 0.2 1.1 1 0 0 1 1 1 0 Metallopeptidase toxin 2 GPI-anchored PF10342.4 EFI28754.1 - 2.7e-10 40.5 0.0 2.7e-10 40.5 0.0 2.3 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Serglycin PF04360.7 EFI28754.1 - 5.4 6.7 8.4 19 4.9 5.8 1.8 1 1 0 1 1 1 0 Serglycin Zn_clus PF00172.13 EFI28756.1 - 8.7e-05 22.3 12.7 0.00014 21.7 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EFI28757.1 - 2.7e-24 85.4 0.7 4.1e-24 84.8 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CDC37_C PF08564.5 EFI28760.1 - 0.069 12.9 1.5 0.074 12.9 1.0 1.0 1 0 0 1 1 1 0 Cdc37 C terminal domain Nucleoplasmin PF03066.10 EFI28760.1 - 1.7 8.1 6.5 1.8 8.0 4.5 1.0 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EFI28760.1 - 1.9 8.8 5.8 2 8.6 4.0 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain But2 PF09792.4 EFI28761.1 - 8e-08 32.1 0.0 2e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Acetyltransf_1 PF00583.19 EFI28762.1 - 6.5e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EFI28762.1 - 0.00012 22.1 0.1 0.0012 19.0 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EFI28762.1 - 0.00047 19.9 0.0 0.06 13.2 0.0 2.8 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EFI28762.1 - 0.001 19.1 0.0 0.0081 16.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MR_MLE_N PF02746.11 EFI28764.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TAF8_C PF10406.4 EFI28764.1 - 0.088 12.8 0.6 4.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term NblA PF04485.7 EFI28764.1 - 1 9.2 3.8 1.1 9.1 1.8 1.6 2 0 0 2 2 2 0 Phycobilisome degradation protein nblA PRC PF05239.11 EFI28765.1 - 0.0079 16.0 0.9 2.1 8.2 0.1 2.4 1 1 1 2 2 2 2 PRC-barrel domain Cache_3 PF14827.1 EFI28765.1 - 0.1 12.5 0.1 18 5.2 0.0 2.4 1 1 1 2 2 2 0 Sensory domain of two-component sensor kinase PGG PF13962.1 EFI28766.1 - 0.11 12.0 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function CbiC PF02570.10 EFI28769.1 - 0.033 13.5 1.4 0.036 13.4 1.0 1.0 1 0 0 1 1 1 0 Precorrin-8X methylmutase GHL6 PF14871.1 EFI28769.1 - 0.041 13.9 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 TrbC PF04956.8 EFI28769.1 - 0.071 13.1 1.7 0.086 12.8 1.1 1.1 1 0 0 1 1 1 0 TrbC/VIRB2 family Podoplanin PF05808.6 EFI28769.1 - 0.081 12.4 0.9 0.14 11.7 0.6 1.4 1 1 0 1 1 1 0 Podoplanin PepSY_2 PF13670.1 EFI28769.1 - 7.3 6.5 7.8 13 5.8 5.4 1.4 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain F-box PF00646.28 EFI28771.1 - 1.4e-11 43.7 12.1 1.5e-05 24.4 1.5 2.6 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 EFI28771.1 - 1.7e-09 37.2 7.3 2.5e-05 23.8 0.8 2.5 2 0 0 2 2 2 2 F-box-like F-box-like_2 PF13013.1 EFI28771.1 - 0.21 11.3 4.1 0.34 10.6 0.8 2.2 2 0 0 2 2 2 0 F-box-like domain F-box PF00646.28 EFI28772.1 - 9.1e-06 25.1 4.3 1.7e-05 24.3 3.0 1.5 1 0 0 1 1 1 1 F-box domain tRNA-synt_His PF13393.1 EFI28773.1 - 1.7e-36 125.8 0.0 7.7e-33 113.8 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EFI28773.1 - 9.2e-19 67.6 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EFI28773.1 - 1.2e-09 37.9 0.1 4.5e-09 36.1 0.1 2.0 1 1 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.15 EFI28773.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EFI28773.1 - 0.021 13.5 0.0 1.5 7.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) F-box PF00646.28 EFI28774.1 - 0.00031 20.3 4.8 0.00031 20.3 3.3 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EFI28774.1 - 0.0057 16.3 1.3 0.014 15.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like IL11 PF07400.6 EFI28774.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Interleukin 11 F-box PF00646.28 EFI28777.1 - 0.00019 21.0 0.2 0.00019 21.0 0.2 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EFI28777.1 - 0.0023 17.5 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EFI28777.1 - 0.14 12.1 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 PRANC domain DUF1685 PF07939.6 EFI28779.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) SKG6 PF08693.5 EFI28783.1 - 3.7 6.9 8.2 13 5.1 5.7 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.6 EFI28784.1 - 0.0032 17.0 3.2 0.0056 16.2 2.2 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.1 EFI28784.1 - 0.0034 17.0 0.1 0.0067 16.1 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family Shisa PF13908.1 EFI28784.1 - 0.0038 17.4 0.1 0.0038 17.4 0.1 2.8 2 1 0 3 3 3 1 Wnt and FGF inhibitory regulator DUF1191 PF06697.7 EFI28784.1 - 0.0038 16.0 0.2 0.006 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Flocculin PF00624.13 EFI28784.1 - 0.036 13.8 1.3 0.12 12.2 0.9 1.9 1 0 0 1 1 1 0 Flocculin repeat Rax2 PF12768.2 EFI28784.1 - 0.047 12.9 0.1 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2668 PF10873.3 EFI28784.1 - 0.096 12.8 0.1 0.096 12.8 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2668) Adeno_E3_CR2 PF02439.10 EFI28784.1 - 0.098 12.2 2.1 0.23 11.0 1.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EFI28784.1 - 0.14 12.5 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EVC2_like PF12297.3 EFI28784.1 - 0.2 10.2 0.1 0.28 9.7 0.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein GMC_oxred_N PF00732.14 EFI28785.1 - 1.3e-63 214.8 0.0 1.8e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EFI28785.1 - 5.3e-35 120.8 0.0 9.2e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EFI28785.1 - 4.7e-05 22.4 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EFI28785.1 - 9.6e-05 22.3 0.0 0.00055 19.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EFI28785.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EFI28785.1 - 0.00043 19.2 0.0 0.0017 17.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EFI28785.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EFI28785.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EFI28785.1 - 0.071 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.14 EFI28786.1 - 1.4e-59 201.7 0.0 1.9e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EFI28786.1 - 6.7e-36 123.7 0.0 1.3e-35 122.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EFI28786.1 - 0.00041 20.3 0.1 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EFI28786.1 - 0.0044 15.9 0.1 0.0068 15.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EFI28786.1 - 0.0055 15.6 0.1 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EFI28786.1 - 0.0093 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EFI28786.1 - 0.047 12.5 0.1 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EFI28786.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Atg14 PF10186.4 EFI28787.1 - 5e-40 137.3 4.1 5.9e-26 91.1 0.0 3.0 2 1 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Med9 PF07544.8 EFI28787.1 - 0.034 13.8 0.1 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Sec8_exocyst PF04048.9 EFI28787.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain